Saccharomyces cerevisiae S288C chromosome X, complete sequence.
type: Entry
definition: Saccharomyces cerevisiae S288C chromosome X, complete sequence.
sequence version: NC_001142.9
sequence date: 2023-01-18
sequence: sequence
division: CON
label: NC_001142.9
type: RefSeq
SIO_000068: refseq
dblink: PRJNA128
keyword: RefSeq
source: Saccharomyces cerevisiae S288C
organism: Saccharomyces cerevisiae S288C
taxonomy: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
reference: 1
references: 34897464
reference: 2
references: 8849441
reference: 3
references: 8641269
reference: 4
reference: 5
reference: 6
reference: 7
comment: REVIEWED REFSEQ: This record has been curated by SGD. The reference\nsequence is identical to BK006943.\n\nOn Apr 26, 2011 this sequence version replaced NC_001142.8.\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: SGD\nAnnotation Status :: Full Annotation\nAnnotation Version :: R64-3-1\nURL :: http://www.yeastgenome.org/\n##Genome-Annotation-Data-END##\nCOMPLETENESS: full length.

sequence
subclass of: SO_0000340
sequence length: 745751
topology: linear
so has quality: SO_0000987
location: 1..745751
location: region:1-745751:1
RO_0002162: 559292

NC_001142
type: RefSeq
SIO_000068: refseq

PRJNA128
type: BioProject
SIO_000068: bioproject

1
title: New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources
author: Engel, S.R.
author: Wong, E.D.
author: Nash, R.S.
author: Aleksander, S.
author: Alexander, M.
author: Douglass, E.
author: Karra, K.
author: Miyasato, S.R.
author: Simison, M.
author: Skrzypek, M.S.
author: Weng, S.
author: Cherry, J.M.
journal: Genetics 220 (4) (2022)
pubmed: 34897464

34897464
type: PubMed
SIO_000068: pubmed

2
title: Life with 6000 genes
author: Goffeau, A.
author: Barrell, B.G.
author: Bussey, H.
author: Davis, R.W.
author: Dujon, B.
author: Feldmann, H.
author: Galibert, F.
author: Hoheisel, J.D.
author: Jacq, C.
author: Johnston, M.
author: Louis, E.J.
author: Mewes, H.W.
author: Murakami, Y.
author: Philippsen, P.
author: Tettelin, H.
author: Oliver, S.G.
journal: Science 274 (5287), 546 (1996)
pubmed: 8849441

8849441
type: PubMed
SIO_000068: pubmed

3
title: Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X
author: Galibert, F.
author: Alexandraki, D.
author: Baur, A.
author: Boles, E.
author: Chalwatzis, N.
author: Chuat, J.C.
author: Coster, F.
author: Cziepluch, C.
author: De Haan, M.
author: Domdey, H.
author: Durand, P.
author: Entian, K.D.
author: Gatius, M.
author: Goffeau, A.
author: Grivell, L.A.
author: Hennemann, A.
author: Herbert, C.J.
author: Heumann, K.
author: Hilger, F.
author: Hollenberg, C.P.
author: Huang, M.E.
author: Jacq, C.
author: Jauniaux, J.C.
author: Katsoulou, C.
author: Karpfinger-Hartl, L. et al.
journal: EMBO J.
volume: 15
issue: 9
pages: 2031-2049
year: 1996
pubmed: 8641269

8641269
type: PubMed
SIO_000068: pubmed

4
title: Direct Submission
journal: Submitted (13-JAN-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA

5
title: Direct Submission
journal: Submitted (04-MAY-2012) Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA
comments: Protein update by submitter

6
title: Direct Submission
journal: Submitted (12-APR-2011) Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA
comments: Sequence update by submitter

7
title: Direct Submission
journal: Submitted (14-DEC-2009) Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA

position:1:1
position: 1
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:745751:1
position: 745751
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

feature:1-745751:1:source
so part of: sequence
organism: Saccharomyces cerevisiae S288C
mol type: genomic DNA
strain: S288C
chromosome: X

559292
type: Taxonomy
SIO_000068: taxonomy

telomere
type: Telomere
subclass of: SO_0000624
RO_0002162: 559292
note: TEL10L; Telomeric region on the left arm of Chromosome X; composed of an X element core sequence, X element combinatorial repeats, a long Y' element, and a short terminal stretch of telomeric repeats
so part of: sequence
location: complement(1..7767)
location: region:1-7767:-1
so has part: feature:1-7767:-1:region

S000028901
type: SGD
SIO_000068: sgd

position:1:-1
position: 1
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:7767:-1
position: 7767
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:1-7767:-1:region

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1001; Autonomously Replicating Sequence
so part of: sequence
location: 65..577
location: region:65-577:1
so has part: feature:65-577:1:region

S000028438
type: SGD
SIO_000068: sgd

position:65:1
position: 65
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:577:1
position: 577
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:65-577:1:region

YJL225C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJL225C
so part of: sequence
location: complement(<466..>6130)
location: region:466-6130:-1
so has part: feature:466-6130:-1:exon
subclass of: SO_0000010

853231
type: Gene
SIO_000068: ncbigene

position:466:-1
position: 466
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:6130:-1
position: 6130
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:466-6130:-1:exon

YJL225C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJL225C
product: Y' element ATP-dependent helicase
transcript id: NM_001181657.1
SIO_010081: YJL225C
subclass of: SO_0000673
so part of: YJL225C
location: complement(join(<466..4581,4970..>6130))
location: region:466-6130:-1
so has part: feature:4970-6130:-1:exon
so has part: feature:466-4581:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:4970-6130:-1:exon

position:4970:-1
position: 4970
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:466-4581:-1:exon

position:4581:-1
position: 4581
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YJL225C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJL225C
EC number: 3.6.4.12
note: Putative Y' element ATP-dependent helicase
codon start: 1
product: Y' element ATP-dependent helicase
translation: MKVSDRRKFEKANFDEFESALNNKNDLVHCPSITLFESIPTEVRSFYEDEKSGLIKVVKFRTGAMDRKRSFEKVVISVMVGKNVKKFLTFVEDEPDFQGGPIPSKYLIPKKINLMVYTLFQVHTLKFNRKDYDTLSLFYLNRGYYNELSFRVLERCHEIASARPNDSSTMRTFTDFVSGAPIVRSLQKSTIRKYGYNLAPYMFLLLHVDELSIFSAYQASLPGEKKVDTERLKRDLCPRKPIEIKYFSQICNDMMNKKDRLGDILHIILRACALNFGAGPRGGAGDEEDRSITNEEPIIPSVDEHGLKVCKLRSPNTPRRLRKTLDAVKALLVSSCACTARDLDIFDDNNGVAMWKWIKILYHEVAQETTLKDSYRITLVPSSDGISLLAFAGPQRNVYVDDTTRRIQLYTDYNKNGSSEPRLKTLDGLTSDYVFYFVTVLRQMQICALGNSYDAFNHDPWMDVVGFEDPNQVTNRDISRIVLYSYMFLNTAKGCLVEYATFRQYMRELPKNAPQKLNFREMRQGLIALGRHCVGSRFETDLYESATSELMANHSVQTGRNIYGVDSFSLTSVSGTTATLLQERASERWIQWLGLESDYHCSFSSTRNAEDVVAGEAASSNHHQKISRVTRKRPREPKSTNDILVAGQKLFGSSFEFRDLHQLRLCYEIYMADTPSVAVQAPPGYGKTELFHLPLIALASKGDVEYVSFLFVPYTVLLANCMIRLGRRGCLNVAPVRNFIEEGYDGVTDLYVGIYDDLASTNFTDRIAAWENIVECTFRTNNVKLGYLIVDEFHNFETEVYRQSQFGGITNLDFDAFEKAIFLSGTAPEAVADAALQRIGLTGLAKKSMDINELKRSEDLSRGLSSYPTRMFNLIKEKSEVPLGHVHKIRKKVESQPEEALKLLLALFESEPESKAIVVASTTNEVEELACSWRKYFRVVWIHGKLGAAEKVSRTKEFVTDGSMQVLIGTKLVTEGIDIKQLMMVIMLDNRLNIIELIQGVGRLRDGGLCYLLSRKNSWAARNRKGELPPIKEGCITEQVREFYGLESKKGKKGQHVGCCGSRTDLSADTVELIERMDRLAEKQATASMSIVALPSSFQESNSSDRYRKYCSSDEDSNTCIHGSANASTNASTNAITTASTNVRTNATTNASTNATTNASTNASTNATTNASTNATTNSSTNATTTASTNVRTSATTTASINVRTSATTTESTNSSTNATTTESTNSSTNATTTESTNSNTSATTTASINVRTSATTTESTNSSTSATTTASINVRTSATTTKSINSSTNATTTESTNSNTNATTTESTNSSTNATTTESTNSSTNATTTESTNSNTSAATTESTNSNTSATTTESTNASAKEDANKDGNAEDNRFHPVTDINKESYKRKGSQMVLLERKKLKAQFPNTSENMNVLQFLGFRSDEIKHLFLYGIDIYFCPEGVFTQYGLCKGCQKMFELCVCWAGQKVSYRRIAWEALAVERMLRNDEEYKEYLEDIEPYHGDPVGYLKYFSVKRREIYSQIQRNYAWYLAITRRRETISVLDSTRGKQGSQVFRMSGRQIKELYFKVWSNLRESKTEVLQYFLNWDEKKCQEEWEAKDDTVVVEALEKGGVFQRLRSMTSAGLQGPQYVKLQFSRHHRQLRSRYELSLGMHLRDQIALGVTPSKVPHWTAFLSMLIGLFYNKTFRQKLEYLLEQISEVWLLPHWLDLANVEVLAADDTRVPLYMLMVAVHKELDSDDVPDGRFDILLCRDSSREVGE
SIO_010081: YJL225C
subclass of: SO_0000673
so part of: YJL225C
location: complement(join(466..4581,4970..6130))
location: region:466-6130:-1
so has part: feature:4970-6130:-1:exon
so has part: feature:466-4581:-1:exon

NP_012311.1
type: Protein
SIO_000068: ncbiprotein

S000003760
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:4970-6130:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:466-4581:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1002; Autonomously Replicating Sequence
so part of: sequence
location: 7445..7943
location: region:7445-7943:1
so has part: feature:7445-7943:1:region

S000028439
type: SGD
SIO_000068: sgd

position:7445:1
position: 7445
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:7943:1
position: 7943
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:7445-7943:1:region

YJL223C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PAU1
locus tag: YJL223C
so part of: sequence
location: complement(<8776..>9138)
location: region:8776-9138:-1
so has part: feature:8776-9138:-1:exon
subclass of: SO_0000010

853232
type: Gene
SIO_000068: ncbigene

position:8776:-1
position: 8776
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:9138:-1
position: 9138
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:8776-9138:-1:exon

YJL223C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PAU1
locus tag: YJL223C
product: seripauperin PAU1
transcript id: NM_001181656.1
SIO_010081: YJL223C
subclass of: SO_0000673
so part of: YJL223C
location: complement(<8776..>9138)
location: region:8776-9138:-1
so has part: feature:8776-9138:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:8776-9138:-1:exon

YJL223C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PAU1
locus tag: YJL223C
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
note: Member of the seripauperin multigene family; encoded mainly in subtelomeric regions; SWAT-GFP and mCherry fusion proteins localize to the vacuole; active during alcoholic fermentation; regulated by anaerobiosis, negatively regulated by oxygen; repressed by heme; identical to Pau14p
codon start: 1
product: seripauperin PAU1
translation: MVKLTSIAAGVAAIAATASATTTLAQSDERVNLVELGVYVSDIRAHLAQYYMFQAAHPTETYPVEVAEAVFNYGDFTTMLTGISPDQVTRMITGVPWYSSRLKPAISSALSKDGIYTIAN
SIO_010081: YJL223C
subclass of: SO_0000673
so part of: YJL223C
location: complement(8776..9138)
location: region:8776-9138:-1
so has part: feature:8776-9138:-1:exon

NP_012312.1
type: Protein
SIO_000068: ncbiprotein

S000003759
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:8776-9138:-1:exon

YJL222W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: VTH2
locus tag: YJL222W
so part of: sequence
location: <11475..>16124
location: region:11475-16124:1
so has part: feature:11475-16124:1:exon
subclass of: SO_0000010

853233
type: Gene
SIO_000068: ncbigene

position:11475:1
position: 11475
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:16124:1
position: 16124
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:11475-16124:1:exon

YJL222W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: VTH2
locus tag: YJL222W
product: signal sequence-binding protein
transcript id: NM_001181655.1
SIO_010081: YJL222W
subclass of: SO_0000673
so part of: YJL222W
location: <11475..>16124
location: region:11475-16124:1
so has part: feature:11475-16124:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:11475-16124:1:exon

YJL222W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: VTH2
locus tag: YJL222W
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0005048 signal sequence binding [PMID:8636229]
experiment: EXISTENCE:genetic interaction:GO:0006623 protein targeting to vacuole [PMID:8636229]
experiment: EXISTENCE:genetic interaction:GO:0006896 Golgi to vacuole transport [PMID:8662642]
note: Putative membrane glycoprotein; has strong similarity to Vth1p and Pep1p/Vps10p; may be involved in vacuolar protein sorting
codon start: 1
product: signal sequence-binding protein
translation: MALFRALYIIWVFLLIPLSNAEEFTPKVTRTLSRYVFDIVNFDDSNTLIRAEEDSVEISFDAGENWKTIDEIEEPIESFVVDPFRGHDRAFAFVKTAPKFYVTDDQGKSWRPLTIPISEKASNYFCDVTTHPIKKKHLIIRCDLLTIKNSGLMYVGREIYTTNDGVSFSQVKPSFGKIDGHISTARCDFIKSSEDSDLGGNDASILCLFRNTEYIESTGSTIDKSELILSADGGETFKELVQFKDKVVSRYEILKHHVIVLTQDDMYNEMSSTNIWISNDVSTFQVARTPTKIRHVNMGQIHEDSIGRIVLPVSRERDDEDSNQPGAAEVLISDSEGLKFLPINWIPNNQFGYINVAYPGFLKGTFFGSFHPFIEYSDRKRKYSRQKVREETKVSVDNGLTWTNLKVVDRENVDLFGCDVTKPERCSLQTHFYDLRNLNPSAGIMMISGIVGDGSAYNWKEEKTFISRDSGLTWRLVHNSTGLYTTGDLGNIIMYIPYRSNENGDVPSKFYYSLDQGKTWGEYDLIMPIYPYRLVSTISDGSGSKFILTGTSITEDPIFITYSIDFSAVFDYKSCEEGDFEDWNLADGKCVNGAKYKYRRRKQDAQCLVKKAFKDLSLDETPCNSCTGSDYECSFEFVRDAKGDCIPDYNLIALSDICDKSKGKSVLVKPLQLIKGDKCKTPMKIESVDIPCDEIPKEGSSDKEIVTTENKFDFEIKFYQYFDTVADESLVMLNSIGDAYISHDGGQTIKRFDTDGEKIVEIVFNPYFNSSAYLFGSKGNIFLTHDRGYSFMIAKLPEARQLGMPLDFSAKAQDTFIYYGGKNCESILSPECHAVAYLTKDGGETFTEMLDNAIHCEFAGTLFKYPSNDDMVMCQVKEKFSQTRSLVSSTDFFQDDRKTVFENIIGYLSTGGYIIVAVPHEDNELRAYVTNDGAEFTEAKFPYDEDIGKQDAFTILGSEEGSIFLHLATNLESGHDFGNLLKSNSNGTSFVTLEHAVNRNTFGYVDFEKVQGLEGIIITNIVSNSEKVGENKEDEQLKTKITFNDGSDWNFLKPPKKDSEGKKFPCDSVSLDKCSLHLHGYTERKDIRDTYSSGSALGMMFGVGNVGDRLLPYEECSTFLTTDGGETWTEVKKGPHQWEYGDHGGVLVLVPENAETDSISYSTDFGKTWKDYKFCGDKVLVKDIITVPRDSALRFLLFGEAKNMGSGSFRTYTIDFRNIFERQCEFDITGRKRADFKYSPLGSRTGCLFGHKTEFLRKTDEKCFIGNIPLSEFSRNVKNCPCTRQDFECDYNFYKASDGTCKLVKGLSSANGADICKKEPDLIEYYDSSGYRKIPLSTCKGGLKLDAHLAPHPCPGKEKAFREKYSINTGAYALVFVTILLVIFFVAWFVYDRGIRRNGGFSRFEEIRLGDDGLIENNRTDRVVNIIVRLGLCISLITKSAFQRAKAGTAQLSSKFRARFGNKKGATYSSLLHDQLSDEPDGFHEDSNDLSSFRGQGSNSEIEQEDVDTSQQEHTSRTDLLGASNIPDALPARSASHESDLAAARSEDK
SIO_010081: YJL222W
subclass of: SO_0000673
so part of: YJL222W
location: 11475..16124
location: region:11475-16124:1
so has part: feature:11475-16124:1:exon

NP_012313.1
type: Protein
SIO_000068: ncbiprotein

S000003758
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:11475-16124:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1003; Autonomously Replicating Sequence
so part of: sequence
location: 16124..16762
location: region:16124-16762:1
so has part: feature:16124-16762:1:region

S000028440
type: SGD
SIO_000068: sgd

position:16762:1
position: 16762
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:16124-16762:1:region

YJL221C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: FSP2
gene: IMA4
locus tag: YJL221C
gene synonym: FSP2
so part of: sequence
location: complement(<16767..>18536)
location: region:16767-18536:-1
so has part: feature:16767-18536:-1:exon
subclass of: SO_0000010

853235
type: Gene
SIO_000068: ncbigene

position:16767:-1
position: 16767
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:18536:-1
position: 18536
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:16767-18536:-1:exon

YJL221C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: FSP2
gene: IMA4
locus tag: YJL221C
gene synonym: FSP2
product: oligo-1,6-glucosidase IMA4
transcript id: NM_001181654.1
SIO_010081: YJL221C
subclass of: SO_0000673
so part of: YJL221C
location: complement(<16767..>18536)
location: region:16767-18536:-1
so has part: feature:16767-18536:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:16767-18536:-1:exon

YJL221C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: FSP2
gene: IMA4
locus tag: YJL221C
gene synonym: FSP2
EC number: 3.2.1.10
experiment: EXISTENCE:genetic interaction:GO:0046352 disaccharide catabolic process [PMID:20562106]
experiment: EXISTENCE:mutant phenotype:GO:0004574 oligo-1,6-glucosidase activity [PMID:20562106]
note: Alpha-glucosidase; weak, but broad substrate specificity for alpha-1,4- and alpha-1,6-glucosides; member of IMA isomaltase family; not required for isomaltose utilization, but Ima4p overexpression allows the ima1 null mutant to grow on isomaltose; identical to IMA3
codon start: 1
product: oligo-1,6-glucosidase IMA4
translation: MTISSAHPETEPKWWKEATIYQIYPASFKDSNNDGWGDMKGIASKLEYIKELGTDAIWISPFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWRSYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVAGLPDAPVIDENSKWQLSDPFTMNGPRIHEFHQEMNKFIRNRVKDGREIMTVGEMRHATDETKRLYTSASRHELSELFNFSHTDVGTSPKFRQNLIPYELKDWKVALAELFRYVNGTDCWSTIYLENHDQPRSITRFGDDSPKNRVISGKLLSVLLVSLSGTLYVYQGQELGEINFKNWPIEKYEDVEVRNNYDAIKEEHGENSKEMKRFLEAIALISRDHARTPMQWSREEPNAGFSGPNAKPWFYLNESFREGINAEDESKDPNSVLNFWKEALRFRKAHKDITVYGYDFEFIDLDNKKLFSFTKKYDNKTLFAALNFSSDSIDFTIPNNSSSFKLEFGNYPRSEVDASSRTLKPWEGRIYISE
SIO_010081: YJL221C
subclass of: SO_0000673
so part of: YJL221C
location: complement(16767..18536)
location: region:16767-18536:-1
so has part: feature:16767-18536:-1:exon

NP_012314.1
type: Protein
SIO_000068: ncbiprotein

S000003757
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:16767-18536:-1:exon

YJL219W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HXT9
locus tag: YJL219W
so part of: sequence
location: <19497..>21200
location: region:19497-21200:1
so has part: feature:19497-21200:1:exon
subclass of: SO_0000010

853236
type: Gene
SIO_000068: ncbigene

position:19497:1
position: 19497
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:21200:1
position: 21200
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:19497-21200:1:exon

YJL219W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HXT9
locus tag: YJL219W
product: hexose transporter HXT9
transcript id: NM_001181652.1
SIO_010081: YJL219W
subclass of: SO_0000673
so part of: YJL219W
location: <19497..>21200
location: region:19497-21200:1
so has part: feature:19497-21200:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:19497-21200:1:exon

YJL219W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: HXT9
locus tag: YJL219W
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0005353 fructose transmembrane transporter activity [PMID:10618490]
experiment: EXISTENCE:mutant phenotype:GO:0005354 galactose transmembrane transporter activity [PMID:10618490]
experiment: EXISTENCE:mutant phenotype:GO:0005355 glucose transmembrane transporter activity [PMID:10618490]
experiment: EXISTENCE:mutant phenotype:GO:0008645 hexose transmembrane transport [PMID:10618490]
experiment: EXISTENCE:mutant phenotype:GO:0015578 mannose transmembrane transporter activity [PMID:10618490]
note: Putative hexose transporter that is nearly identical to Hxt11p; has similarity to major facilitator superfamily (MFS) transporters, expression of HXT9 is regulated by transcription factors Pdr1p and Pdr3p
codon start: 1
product: hexose transporter HXT9
translation: MSGVNNTSANDLSTTESNSNSVANAPSVKTEHNDSKNSLNLDATEPPIDLPQKPLSAYTTVAILCLMIAFGGFIFGWDTGTISGFVNLSDFIRRFGQKNDKGTYYLSKVRMGLIVSIFNIGCAIGGIVLSKVGDIYGRRIGLITVTAIYVVGILIQITSINKWYQYFIGRIISGLGVGGIAVLSPMLISEVAPKQIRGTLVQLYQLMCTMGIFLGYCTNYGTKNYHNATQWRVGLGLCFAWTTFMVSGMMFVPESPRYLIEVGKDEEAKRSLSKSNKVSVDDPALLAEYDTIKAGIELEKLAGNASWSELLSTKTKVFQRVLMGVMIQSLQQLTGDNYFFYYGTTIFKSVGLKDSFQTSIIIGVVNFFSSFIAVYTIERFGRRTCLLWGAASMLCCFAVFASVGVTKLWPQGSSHQDITSQGAGNCMIVFTMFFIFSFATTWAGGCYVIVSETFPLRVKSRGMAIATAANWMWGFLISFFTPFITGAINFYYGYVFLGCLVFAYFYVFFFVPETKGLTLEEVNTMWLEGVPAWKSASWVPPERRTADYDADAIDHDDRPIYKRFFSS
SIO_010081: YJL219W
subclass of: SO_0000673
so part of: YJL219W
location: 19497..21200
location: region:19497-21200:1
so has part: feature:19497-21200:1:exon

NP_012316.1
type: Protein
SIO_000068: ncbiprotein

S000003755
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:19497-21200:1:exon

YJL218W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJL218W
so part of: sequence
location: <21973..>22563
location: region:21973-22563:1
so has part: feature:21973-22563:1:exon
subclass of: SO_0000010

853237
type: Gene
SIO_000068: ncbigene

position:21973:1
position: 21973
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:22563:1
position: 22563
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:21973-22563:1:exon

YJL218W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJL218W
product: acetyltransferase
transcript id: NM_001181651.1
SIO_010081: YJL218W
subclass of: SO_0000673
so part of: YJL218W
location: <21973..>22563
location: region:21973-22563:1
so has part: feature:21973-22563:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:21973-22563:1:exon

YJL218W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJL218W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:31945465]
note: Mitochondrial protein, putative acetyltransferase; similar to bacterial galactoside O-acetyltransferases; induced by oleate in OAF1/PIP2-dependent manner; promoter contains oleate response element consensus sequence; mutation decreases salt tolerance; non-essential gene
codon start: 1
product: acetyltransferase
translation: MGVLENIVPGELYDANYDPDLLKIRKETKIKLHEYNTLSPADENKKSQVIRELLGSCTDNFIIEPPFYCDYGSNIYIGDNFYANHNLVILDGAKVVIGDNVFIAPNVGIYTAGHPIDVERRLQGLEYAMPVTIGDNVWIGGGVSIIPGVNIGKNSVIAAGSVVIRDIPENVVAAGNPCKVIRKITEKDSTTTNYRK
SIO_010081: YJL218W
subclass of: SO_0000673
so part of: YJL218W
location: 21973..22563
location: region:21973-22563:1
so has part: feature:21973-22563:1:exon

NP_012317.1
type: Protein
SIO_000068: ncbiprotein

S000003754
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:21973-22563:1:exon

YJL217W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: REE1
locus tag: YJL217W
so part of: sequence
location: <23133..>23729
location: region:23133-23729:1
so has part: feature:23133-23729:1:exon
subclass of: SO_0000010

853238
type: Gene
SIO_000068: ncbigene

position:23133:1
position: 23133
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:23729:1
position: 23729
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:23133-23729:1:exon

YJL217W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: REE1
locus tag: YJL217W
product: Ree1p
transcript id: NM_001181650.1
SIO_010081: YJL217W
subclass of: SO_0000673
so part of: YJL217W
location: <23133..>23729
location: region:23133-23729:1
so has part: feature:23133-23729:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:23133-23729:1:exon

YJL217W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: REE1
locus tag: YJL217W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
note: Cytoplasmic protein involved in the regulation of enolase (ENO1); mRNA expression is induced by calcium shortage, copper deficiency (via Mac1p) and the presence of galactose (via Gal4p); mRNA expression is also regulated by the cell cycle
codon start: 1
product: Ree1p
translation: MVESKNTELSQGTWLNKPKSVFQEAGKVTLETDEKTDFWRETFYGFTRDSGHFLGVETGSAFTAQVRVQGSYESLYDQAGIMVRIDDGHWLKAGIEISDGHAMLSSVLTNGKSDWSTAVYGGNARDFWLRVTVEKGVLRIQVSSDKKTWPLVRLAPFPTSDHYLVGPMACTPERGGLKVTFSEWSLTAPLGKALHDLS
SIO_010081: YJL217W
subclass of: SO_0000673
so part of: YJL217W
location: 23133..23729
location: region:23133-23729:1
so has part: feature:23133-23729:1:exon

NP_012318.1
type: Protein
SIO_000068: ncbiprotein

S000003753
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:23133-23729:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1004; Autonomously Replicating Sequence
so part of: sequence
location: 23662..24158
location: region:23662-24158:1
so has part: feature:23662-24158:1:region

S000028441
type: SGD
SIO_000068: sgd

position:23662:1
position: 23662
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:24158:1
position: 24158
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:23662-24158:1:region

YJL216C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: IMA5
locus tag: YJL216C
so part of: sequence
location: complement(<24341..>26086)
location: region:24341-26086:-1
so has part: feature:24341-26086:-1:exon
subclass of: SO_0000010

853214
type: Gene
SIO_000068: ncbigene

position:24341:-1
position: 24341
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:26086:-1
position: 26086
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:24341-26086:-1:exon

YJL216C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: IMA5
locus tag: YJL216C
product: oligo-1,6-glucosidase IMA5
transcript id: NM_001181649.1
SIO_010081: YJL216C
subclass of: SO_0000673
so part of: YJL216C
location: complement(<24341..>26086)
location: region:24341-26086:-1
so has part: feature:24341-26086:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:24341-26086:-1:exon

YJL216C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: IMA5
locus tag: YJL216C
EC number: 3.2.1.10
experiment: EXISTENCE:direct assay:GO:0004574 oligo-1,6-glucosidase activity [PMID:20471265]
experiment: EXISTENCE:genetic interaction:GO:0046352 disaccharide catabolic process [PMID:20562106|PMID:20471265]
experiment: EXISTENCE:mutant phenotype:GO:0004574 oligo-1,6-glucosidase activity [PMID:20562106]
note: Alpha-glucosidase; specificity for isomaltose, maltose, and palatinose, but not alpha-methylglucoside; most distant member of the IMA isomaltase family, but with similar catalytic properties as Ima1p and Ima2p; not required for isomaltose utilization, but Ima5p overexpression allows the ima1 null mutant to grow on isomaltose; can cleave alpha-1,3 linkage of nigerose and turanose and alpha-1,5 linkage of leucrose and is very sensitive to temperature in vitro
codon start: 1
product: oligo-1,6-glucosidase IMA5
translation: MTIIHNPKWWKEATVYQIYPASFKDSNNDGWGDLAGITSKLDYVKELGVDAIWVCPFYDSPQEDMGYDIANYEKVWPRYGTNEDCFQMIEEAHKRGIKVIVDLVINHCSEEHEWFKESRSSKANPKRDWFFWRPPKGYDEKGNPIPPNNWRSFFGGSAWRYDEKTGEFFLHVFALGQPDFNWENEECRKAIYDSSVGYWLRHNVDGFRIDVGSMYSKVEGLPDAPITDPTVPYQKGTEFFINGPRIHEYHKEMHNYMLSQVPEGKEIMTVGEVGIGNEDDFRVYTSAKEGELNMMFNFKHTSVGENPKCKYELIPFTLKDFKLALAESFLFIENTDCWSTIYLENHDQPRSVSRFGSDSPKWREISSKMLATLIISLTGTVFIYQGQELGMPNFKNRKIEQIKCVEGTGTYAAIKRDYGEDSEKMKKFFEALALISRDHGRTPFPWSADEPSAGFSKDAKPWIDMNESFRDGINAEAELKDKNSVFFFWKKALQVRKEHKDILVYGHNFQFIDLDNDKLFMFTKDTDNKKMFAVFNFSSDNTDFSVPDNEASYTMFFGNYANSNGDSRTLQPWEGRLYLLK
SIO_010081: YJL216C
subclass of: SO_0000673
so part of: YJL216C
location: complement(24341..26086)
location: region:24341-26086:-1
so has part: feature:24341-26086:-1:exon

NP_012319.1
type: Protein
SIO_000068: ncbiprotein

S000003752
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:24341-26086:-1:exon

YJL214W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HXT8
locus tag: YJL214W
so part of: sequence
location: <26887..>28596
location: region:26887-28596:1
so has part: feature:26887-28596:1:exon
subclass of: SO_0000010

853216
type: Gene
SIO_000068: ncbigene

position:26887:1
position: 26887
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:28596:1
position: 28596
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:26887-28596:1:exon

YJL214W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HXT8
locus tag: YJL214W
product: hexose transporter HXT8
transcript id: NM_001181647.1
SIO_010081: YJL214W
subclass of: SO_0000673
so part of: YJL214W
location: <26887..>28596
location: region:26887-28596:1
so has part: feature:26887-28596:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:26887-28596:1:exon

YJL214W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: HXT8
locus tag: YJL214W
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0005353 fructose transmembrane transporter activity [PMID:10618490]
experiment: EXISTENCE:mutant phenotype:GO:0005355 glucose transmembrane transporter activity [PMID:10618490]
experiment: EXISTENCE:mutant phenotype:GO:0008645 hexose transmembrane transport [PMID:10618490]
experiment: EXISTENCE:mutant phenotype:GO:0015578 mannose transmembrane transporter activity [PMID:10618490]
note: hypothetical protein with similarity to hexose transporters; expression is induced by low levels of glucose and repressed by high levels of glucose
codon start: 1
product: hexose transporter HXT8
translation: MTDRKTNLPEEPIFEEAEDDGCPSIENSSHLSVPTVEENKDFSEYNGEEAEEVVVPEKPASAYATVSIMCLCMAFGGFMSGWDTGTISGFVNQTDFLRRFGNYSHSKNTYYLSNVRTGLIVSIFNVGSAIGCLFLSKLGDIYGRCMGLIIVIVVYMVGIVIQIASIDKWYQYFIGRIIAGIGAGSISVLAPMLISETAPKHIRGTLLACWQLMVTFAIFLGYCTNYGTKTYSNSVQWRVPLGLCFAWAIIMIGGMTFVPESPRFLVQVGKIEQAKASFAKSNKLSVDDPAVVAEIDLLVAGVEAEEAMGTASWKELFSRKTKVFQRLTMTVMINSLQQLTGDNYFFYYGTTIFKSVGMNDSFETSIVLGIVNFASCFFSLYSVDKLGRRRCLLLGAATMTACMVIYASVGVTRLYPNGKSEPSSKGAGNCTIVFTCFYIFCFSCTWGPVCYVIISETFPLRVRSKCMSVATAANLLWGFLIGFFTPFITSAINFYYGYVFMGCLAFSYFYVFFFVPETKGLTLEEVDEMWMDGVLPWKSESWVPASRRDGDYDNEKLQHDEKPFYKRMF
SIO_010081: YJL214W
subclass of: SO_0000673
so part of: YJL214W
location: 26887..28596
location: region:26887-28596:1
so has part: feature:26887-28596:1:exon

NP_012321.1
type: Protein
SIO_000068: ncbiprotein

S000003750
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:26887-28596:1:exon

YJL213W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJL213W
so part of: sequence
location: <32163..>33158
location: region:32163-33158:1
so has part: feature:32163-33158:1:exon
subclass of: SO_0000010

853217
type: Gene
SIO_000068: ncbigene

position:32163:1
position: 32163
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:33158:1
position: 33158
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:32163-33158:1:exon

YJL213W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJL213W
product: uncharacterized protein
transcript id: NM_001181646.1
SIO_010081: YJL213W
subclass of: SO_0000673
so part of: YJL213W
location: <32163..>33158
location: region:32163-33158:1
so has part: feature:32163-33158:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:32163-33158:1:exon

YJL213W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJL213W
note: hypothetical protein that may interact with ribosomes; periodically expressed during the yeast metabolic cycle; phosphorylated in vitro by the mitotic exit network (MEN) kinase complex, Dbf2p/Mob1p
codon start: 1
product: uncharacterized protein
translation: MLMPKSVALLRIRYTLEAALARGFTTVRDCGGAEGFLKAEIRQGSLNGPRLITCGHAISQTGGHGDLRSGALPASAFDSCSCHFGQVGVVADGVPECYKAAREEFRRGADFIKIMGGGGVASPTDKISNKQFCDDEIKALVDVANSYHTYVTAHAYTAEAIQNCIKLGVKGIEHGNLLDERTAELMAELGCYLTPTLVTYKVMGSDQFSAFLGPENSRKNTEVLYKGIDAMKIAQKKKVKICFGSDLLGPLYGYQTQEFRIRGKVQTTQEILLSATVTPAEMNGLGDKLGQIKPGFIADLLMMKSNPLDDITILDEPESNILFVMKEGRIY
SIO_010081: YJL213W
subclass of: SO_0000673
so part of: YJL213W
location: 32163..33158
location: region:32163-33158:1
so has part: feature:32163-33158:1:exon

NP_012322.1
type: Protein
SIO_000068: ncbiprotein

S000003749
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:32163-33158:1:exon

YJL212C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: DUG4
alternative label: GSH11
alternative label: HGT1
gene: OPT1
locus tag: YJL212C
gene synonym: DUG4; GSH11; HGT1
so part of: sequence
location: complement(<33850..>36249)
location: region:33850-36249:-1
so has part: feature:33850-36249:-1:exon
subclass of: SO_0000010

853218
type: Gene
SIO_000068: ncbigene

position:33850:-1
position: 33850
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:36249:-1
position: 36249
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:33850-36249:-1:exon

YJL212C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: DUG4
alternative label: GSH11
alternative label: HGT1
gene: OPT1
locus tag: YJL212C
gene synonym: DUG4; GSH11; HGT1
product: oligopeptide transporter OPT1
transcript id: NM_001181645.1
SIO_010081: YJL212C
subclass of: SO_0000673
so part of: YJL212C
location: complement(<33850..>36249)
location: region:33850-36249:-1
so has part: feature:33850-36249:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:33850-36249:-1:exon

YJL212C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: DUG4
alternative label: GSH11
alternative label: HGT1
gene: OPT1
locus tag: YJL212C
gene synonym: DUG4; GSH11; HGT1
experiment: EXISTENCE:direct assay:GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity [PMID:16149917]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:19496824]
experiment: EXISTENCE:direct assay:GO:0006857 oligopeptide transport [PMID:16149917]
experiment: EXISTENCE:mutant phenotype:GO:0005886 plasma membrane [PMID:10788431]
experiment: EXISTENCE:mutant phenotype:GO:0035673 oligopeptide transmembrane transporter activity [PMID:10652283]
note: Proton-coupled oligopeptide transporter of the plasma membrane; also transports glutathione and phytochelatin; member of the OPT family
codon start: 1
product: oligopeptide transporter OPT1
translation: MSTIYRESDSLESEPSPTPTTIPIQINMEEEKKDAFVKNIDEDVNNLTATTDEEDRDPESQKFDRHSIQEEGLVWKGDPTYLPNSPYPEVRSAVSIEDDPTIRLNHWRTWFLTTVFVVVFAGVNQFFSLRYPSLEINFLVAQVVCYPIGRILALLPDWKCSKVPFFDLNPGPFTKKEHAVVTIAVALTSSTAYAMYILNAQGSFYNMKLNVGYQFLLVWTSQMIGYGAAGLTRRWVVNPASSIWPQTLISVSLFDSLHSRKVEKTVANGWTMPRYRFFLIVLIGSFIWYWVPGFLFTGLSYFNVILWGSKTRHNFIANTIFGTQSGLGALPITFDYTQVSQAMSGSVFATPFYVSANTYASVLIFFVIVLPCLYFTNTWYAKYMPVISGSTYDNTQNKYNVTKILNEDYSINLEKYKEYSPVFVPFSYLLSYALNFAAVIAVFVHCILYHGKDIVAKFKDRKNGGTDIHMRIYSKNYKDCPDWWYLLLQIVMIGLGFVAVCCFDTKFPAWAFVIAILISLVNFIPQGILEAMTNQHVGLNIITELICGYMLPLRPMANLLFKLYGFIVMRQGLNLSRDLKLAMYMKVSPRLIFAVQIYATIISGMVNVGVQEWMMHNIDGLCTTDQPNGFTCANGRTVFNASIIWSLPKYLFSSGRIYNPLMWFFLIGLLFPLAVYAVQWKFPKFKFAKHIHTPVFFTGPGNIPPSTPYNYSLFFAMSFCLNLIRKRWRAWFNKYNFVMGAGVEAGVAISVVIIFLCVQYPGGKLSWWGNNVWKRTYDNDYKKFYTLKKGETFGYDKWW
SIO_010081: YJL212C
subclass of: SO_0000673
so part of: YJL212C
location: complement(33850..36249)
location: region:33850-36249:-1
so has part: feature:33850-36249:-1:exon

NP_012323.1
type: Protein
SIO_000068: ncbiprotein

S000003748
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:33850-36249:-1:exon

YJL210W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CRT1
alternative label: PAS5
gene: PEX2
locus tag: YJL210W
gene synonym: CRT1; PAS5
so part of: sequence
location: <36919..>37734
location: region:36919-37734:1
so has part: feature:36919-37734:1:exon
subclass of: SO_0000010

853219
type: Gene
SIO_000068: ncbigene

position:36919:1
position: 36919
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:37734:1
position: 37734
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:36919-37734:1:exon

YJL210W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CRT1
alternative label: PAS5
gene: PEX2
locus tag: YJL210W
gene synonym: CRT1; PAS5
product: ubiquitin-protein ligase peroxin 2
transcript id: NM_001181643.1
SIO_010081: YJL210W
subclass of: SO_0000673
so part of: YJL210W
location: <36919..>37734
location: region:36919-37734:1
so has part: feature:36919-37734:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:36919-37734:1:exon

YJL210W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CRT1
alternative label: PAS5
gene: PEX2
locus tag: YJL210W
gene synonym: CRT1; PAS5
experiment: EXISTENCE:direct assay:GO:0000209 protein polyubiquitination [PMID:24034674]
experiment: EXISTENCE:direct assay:GO:0005778 peroxisomal membrane [PMID:12876220]
experiment: EXISTENCE:direct assay:GO:0061630 ubiquitin protein ligase activity [PMID:19687296|PMID:22471590]
experiment: EXISTENCE:direct assay:GO:1990429 peroxisomal importomer complex [PMID:22375831]
experiment: EXISTENCE:mutant phenotype:GO:0016558 protein import into peroxisome matrix [PMID:15536088]
note: RING-finger peroxin and E3 ubiquitin ligase; peroxisomal membrane protein with a C-terminal zinc-binding RING domain, forms translocation subcomplex with Pex10p and Pex12p which functions in peroxisomal matrix protein import
codon start: 1
product: ubiquitin-protein ligase peroxin 2
translation: MSRVAQLDSIALDKELYGQFWSEFNAAFNTSEHKEEWELALNTVVFMCATRFLPHYGSSCTYGSALSGVVFQCRKRTLYVVTVLAGYVWKKITHIIFNGPHCGNQMMWLKLYKWVNLLYHGCDVTNFLRFLAAEGPNARAFLSPLYRAFNVHSTRLIRDGSAIASEFYSNSVFAGLEYQNRQLLWNALLELFSNTLLTKRGLLTFVKKPPRSRSTTTYKTVCPRCGGFPTNPYQIACCRANYCYVCVVKALEWSMCDACGSSGRLTASPVY
SIO_010081: YJL210W
subclass of: SO_0000673
so part of: YJL210W
location: 36919..37734
location: region:36919-37734:1
so has part: feature:36919-37734:1:exon

NP_012325.1
type: Protein
SIO_000068: ncbiprotein

S000003746
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:36919-37734:1:exon

YJL209W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CBP1
locus tag: YJL209W
so part of: sequence
location: <38005..>39969
location: region:38005-39969:1
so has part: feature:38005-39969:1:exon
subclass of: SO_0000010

853221
type: Gene
SIO_000068: ncbigene

position:38005:1
position: 38005
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:39969:1
position: 39969
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:38005-39969:1:exon

YJL209W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CBP1
locus tag: YJL209W
product: Cbp1p
transcript id: NM_001181642.1
SIO_010081: YJL209W
subclass of: SO_0000673
so part of: YJL209W
location: <38005..>39969
location: region:38005-39969:1
so has part: feature:38005-39969:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:38005-39969:1:exon

YJL209W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CBP1
locus tag: YJL209W
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:9343381]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:2104848|PMID:22842922]
experiment: EXISTENCE:mutant phenotype:GO:0000958 mitochondrial mRNA catabolic process [PMID:9343381]
experiment: EXISTENCE:mutant phenotype:GO:0009060 aerobic respiration [PMID:9343381]
note: Mitochondrial protein, regulator of COB mRNA stability and translation; interacts with the 5'-untranslated region of the COB mRNA; found in a complex at the inner membrane along with Pet309p; localizes to mitochondrial foci upon DNA replication stress
codon start: 1
product: Cbp1p
translation: MFLPRLVRYRTERFIKMVPTRTLRRINHSSRDPIQKQVLALIKANANLNDNDKLKIRKYWSDMADYKSLRKQENSLLESSILHEVKIEDFISFINRTKTSSMTTRGIYRRECLYQCKKNLDLVNQVVSQVSSVRHQKPLTTQLDTMRWCVDDAIGTGDIVMAADLFLLYYRLFTDDKKLDEQYAKKIISVLAYPNPLHDHVHLVKYLQLNSLFESITGGGIKLTRFQLETLSNKALGLSNEAPQLCKAILNKLMNINYSLTNDLKLRDDQVLLAYKSIDENYRRGNVASVYSIWNKIKEHYVSISAHDSRIIYKVFKICTHNRAYRSICSEMFWQLTPEYYCNNPLILPAIIDFITKQDSLTMAKELMQNINRYTLPENHHIVWLNKRCLSSLLRMHLKFNDSNGVDRVLKQITTNFRALSQENYQAIIIHLFKTQNLDHIAKAVKLLDTIPPGQAMLAYGSIINEVVDWKLASKVKFTDNLMALVNDLLTKAHDFDPDHRNSLWNVVSALYIKKLCHYKKRDGKFVANAKKDIDLAKLLYINAAKRSKTYWTKSNCNPFIASSPCDVKLKVNNQNRFTILRNIALSALQIGRTDIFLWACAELYQNGMTIEELKLDWNFILKHQIRNSEFKTNKEIIQDIKKHGVSAVKRYLR
SIO_010081: YJL209W
subclass of: SO_0000673
so part of: YJL209W
location: 38005..39969
location: region:38005-39969:1
so has part: feature:38005-39969:1:exon

NP_012326.1
type: Protein
SIO_000068: ncbiprotein

S000003745
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:38005-39969:1:exon

YJL208C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: NUC1
locus tag: YJL208C
so part of: sequence
location: complement(<40194..>41183)
location: region:40194-41183:-1
so has part: feature:40194-41183:-1:exon
subclass of: SO_0000010

853222
type: Gene
SIO_000068: ncbigene

position:40194:-1
position: 40194
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:41183:-1
position: 41183
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:40194-41183:-1:exon

YJL208C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: NUC1
locus tag: YJL208C
product: ribonuclease
transcript id: NM_001181641.1
SIO_010081: YJL208C
subclass of: SO_0000673
so part of: YJL208C
location: complement(<40194..>41183)
location: region:40194-41183:-1
so has part: feature:40194-41183:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:40194-41183:-1:exon

YJL208C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: NUC1
locus tag: YJL208C
experiment: EXISTENCE:direct assay:GO:0004520 endodeoxyribonuclease activity [PMID:3286639]
experiment: EXISTENCE:direct assay:GO:0004529 exodeoxyribonuclease activity [PMID:3286639]
experiment: EXISTENCE:direct assay:GO:0004540 ribonuclease activity [PMID:3286639]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:17244531]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005743 mitochondrial inner membrane [PMID:17244531|PMID:3286639]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:31266891]
experiment: EXISTENCE:direct assay:GO:0006308 DNA catabolic process [PMID:3286639]
experiment: EXISTENCE:direct assay:GO:0006401 RNA catabolic process [PMID:3286639]
experiment: EXISTENCE:direct assay:GO:0051607 defense response to virus [PMID:31266891]
experiment: EXISTENCE:mutant phenotype:GO:0006309 apoptotic DNA fragmentation [PMID:22727375]
experiment: EXISTENCE:mutant phenotype:GO:0006310 DNA recombination [PMID:8087883]
experiment: EXISTENCE:mutant phenotype:GO:0006915 apoptotic process [PMID:17244531]
note: Major mitochondrial nuclease; has RNAse and DNA endo- and exonucleolytic activities; roles in mitochondrial recombination, apoptosis and maintenance of polyploidy; involved in fragmentation of genomic DNA during PND (programmed nuclear destruction); encodes ortholog of mammalian endoG
codon start: 1
product: ribonuclease
translation: MCSRILLSGLVGLGAGTGLTYLLLNKHSPTQIIETPYPPTQKPNSNIQSHSFNVDPSGFFKYGFPGPIHDLQNREEFISCYNRQTQNPYWVLEHITPESLAARNADRKNSFFKEDEVIPEKFRGKLRDYFRSGYDRGHQAPAADAKFSQQAMDDTFYLSNMCPQVGEGFNRDYWAHLEYFCRGLTKKYKSVRIVTGPLYLPKKDPIDNKFRVNYEVIGNPPSIAVPTHFFKLIVAEAPTANPAREDIAVAAFVLPNEPISNETKLTDFEVPIDALERSTGLELLQKVPPSKKKALCKEVNCQIVVRDFSNAAIKQSKDVKLLPPPKKRN
SIO_010081: YJL208C
subclass of: SO_0000673
so part of: YJL208C
location: complement(40194..41183)
location: region:40194-41183:-1
so has part: feature:40194-41183:-1:exon

NP_012327.1
type: Protein
SIO_000068: ncbiprotein

S000003744
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:40194-41183:-1:exon

YJL207C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: LAA1
locus tag: YJL207C
so part of: sequence
location: complement(<41389..>47433)
location: region:41389-47433:-1
so has part: feature:41389-47433:-1:exon
subclass of: SO_0000010

853223
type: Gene
SIO_000068: ncbigene

position:41389:-1
position: 41389
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:47433:-1
position: 47433
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:41389-47433:-1:exon

YJL207C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: LAA1
locus tag: YJL207C
product: Laa1p
transcript id: NM_001181640.1
SIO_010081: YJL207C
subclass of: SO_0000673
so part of: YJL207C
location: complement(<41389..>47433)
location: region:41389-47433:-1
so has part: feature:41389-47433:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:41389-47433:-1:exon

YJL207C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: LAA1
locus tag: YJL207C
experiment: EXISTENCE:direct assay:GO:0030136 clathrin-coated vesicle [PMID:14562095]
experiment: EXISTENCE:genetic interaction:GO:0042147 retrograde transport, endosome to Golgi [PMID:16687571]
experiment: EXISTENCE:mutant phenotype:GO:0008104 protein localization [PMID:16687571]
experiment: EXISTENCE:mutant phenotype:GO:0035653 clathrin-coated vesicle cargo loading, AP-1-mediated [PMID:30523155]
experiment: EXISTENCE:mutant phenotype:GO:0042147 retrograde transport, endosome to Golgi [PMID:16687571]
note: AP-1 accessory protein; colocalizes with clathrin to the late-Golgi apparatus; involved in TGN-endosome transport; physically interacts with AP-1; similar to the mammalian p200; may interact with ribosomes; YJL207C is a non-essential gene
codon start: 1
product: Laa1p
translation: MANRSLKKVIETSSNNGHDLLTWITTNLEKLICLKEVNDNEIQEVKEIHTQLDEFVRYISVLENTDDLELHSVFISLSQLYTISIWRLKDEYPGVVFDSAAFLTNVLCEEDVSIDDGDTDPNQKKKKKKSSTKKKKYIYSPAKDIACTILVQLFENFGSSISSLIPLLFNAIFKNLKKIMEKSKYYHATFMTTLLQLFNAILRNSNNDDKILDPATYAKFSKLSKTVFDSISTDEKDFSVTFVSVLIECWTAHFKQTNFIREHSHDIIETIYSRFTEGEIGVYGFANDETRIFTAKSLAEILFDYYFSKNILTLQEVWSIYVKIFLNCDTRDVESGCFESIIHLINLNLLADNTFLSNSKYLDIVLSLSGVFSSYEVNNRSMNTLSRYLRYFQHMHEVILPHLNDSAKTQMLYYILGCSDTYQSSSKSDSASNFKYSIDAKPETQWLTLLQLDFTYVLISDLGSTFTTEENTVKEIRDKLVDLATCEIFTIRVHTVEILKVFLNNCPEYLSETIENSLRALSTDFKSTGKFIFHKNHGHAFIIANLIKGAESDYISYELIMRITVFSTSFIKNNTTSTSSNLYFKGLLCWILLIGLMNYKDEQYLKLQIPQLFLFWKVLLTHTYTYHDEDELYKNLEIRNHALTCLLTYLSNTTIDKEMAKQVSYLLTKCSNFNHSIDLKSKNIDNALLHNENRILQVYLKLEKYINSDFNSSLLILIVKNFSDPNLYTESSSSVLGSLKDIGNRKVSNKDDMESNIVLESSINTLLRQNNGFAFGLSSKITGDRIVNLSMSSAYKYDESISGSWPSKDYNWYNIFEVEVSKPISPILSLDSLILLYGSGSYSQIDRYAPQVTTSLIDSSMELFSSVFPFLNSKIQYSIMETLNLSMFSKMTTPLRSVAVAANVCSALHNALRIMQENNLELDYSVGQLIIESIKKIQFFNDIFLTKIKADCVGLLTAAIARTLGDEERQKFLTEQSRIFIKNVADMDEPYLRMFHVLSLATIFKYNSQYANFEEYFDVIFALMRDPHPVVHSWSLKAMHILLEKHLVIDLKTAALLLSSMEELLVQDKYGIYGRSTLRCNYNRDFNSHVAIGEISRTLTETVGPNFLELNTKVLDSFRNITLSMLISNNILNSITSIKMFENIATFKMKNILNYEIFILASKSIIKSSIVTGIGSSYFDTTFTGSNELISRTSSLKGAFENFDLLTLLYKLQMEEFFMKEMENLSWRYLALFPNSGSVKNYFTEWILHTFKRDNHWFDKLYSIFNMSLGRLFQSYNRDVSALLEVNGLKKSSEKEIKGEEEESIANVNQLTDTDAGGLDSENLQWKSRQIILNLILMLCLESEKYENLLLALSNKIADLIKISFRGSTVRNEGMKLTGLHILNFVLKNYSTMRDPQVPGSSILEQQEAQITSALMPAFSKGSSPTVMSFAITVAAEVLASNIMPPDKLGRISQLLIDLLGNFKDPNSGIRIGEAIIVTPKAKRKIELAVLDAWAEVVQRSITSSNDALFSFTRKYWSILVPLWIISLREYMMIKYNDNDSTVQVKNDSKENSLIEPRSTKIELYEPVWLNFVEALGCTLDSDVQVILASLNDEELEYFLFILFSQCLEAIVKNIDDHSVKMQVLPALHNVLKSNLCIKSIFEDDIITEVVEIMDRLISTGDSKEEFLLVDIISDLIIGYSKCNATPETFLQDIDKLYELLRLLMTIISERLPFIKYNVLTSEEDDNEIKISPTDISLLKKTFIAFESNISNFDNMFKVDLYSCLLFIIGKIYECSHREVIIPIILPLFKALVKALTESEDEKNIVLLEIFYGSIKDVIYHKLDSKNKVATILILLSNGYSKLSFQELNQCANILSEALNNPATQPIALQGFKRIISNIFKYPLLQYFMKLVIKRFFQDIQTNDSLSQASIKTKLIIQFSEEVIKQDHQKASLSIALCLSFFAAYHSAYTEKIDNEVASGIVALAKLDKNSFKEAISSTISPQQKAIIGSVMEAYVKSQS…
SIO_010081: YJL207C
subclass of: SO_0000673
so part of: YJL207C
location: complement(41389..47433)
location: region:41389-47433:-1
so has part: feature:41389-47433:-1:exon

NP_012328.1
type: Protein
SIO_000068: ncbiprotein

S000003743
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:41389-47433:-1:exon

YJL206C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJL206C
so part of: sequence
location: complement(<47659..>49935)
location: region:47659-49935:-1
so has part: feature:47659-49935:-1:exon
subclass of: SO_0000010

853224
type: Gene
SIO_000068: ncbigene

position:47659:-1
position: 47659
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:49935:-1
position: 49935
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:47659-49935:-1:exon

YJL206C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJL206C
product: uncharacterized protein
transcript id: NM_001181638.1
SIO_010081: YJL206C
subclass of: SO_0000673
so part of: YJL206C
location: complement(<47659..>49935)
location: region:47659-49935:-1
so has part: feature:47659-49935:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:47659-49935:-1:exon

YJL206C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJL206C
note: hypothetical protein; similar to transcriptional regulators from the Zn[2]-Cys[6] binuclear cluster protein family; mRNA is weakly cell cycle regulated, peaking in S phase; induced rapidly upon MMS treatment
codon start: 1
product: uncharacterized protein
translation: MTPKESGKPISCAMKKLKGKRSKILVLSRDAGTNELKPTKGRAHRACIACRKRKVRCSGNIPCRLCQTNSYECKYDRPPRNSSVFDREVSDDSSLYAQRASHEREDSKGPISSIDYKKVVETIFPPETLRQILASSSFNSQNFLDTIKTCLLQGQLNVNQVIRQSLPKDTPWHMQTSVPLPPREIALKFIQKTWDCACVLFRFYHRPTIISILDSIYEAEKHGKQYTPEQVKTQPLIYSVLAVGALFSKEDLSKDSKATREFYTDEGYRYFLEAKNSLDFSNITDIYSIQAIFMMTIFLQCSANLKACYSFIGIALRAALKEGLHRRSSIVGPTPIQDETKKRLFWSVYKLDLYMNCILGFPSGIDESDIDQEFPLDVDDENISTIGIKFQDWRTISSCGMNNKHTKLILIMSRIYKLMYSLRRKPLEEDSRTQIVSLNDQLDNWYAQLPDILKVDTIRYRQTQPPLTVSANDTSSPYTKPKKLLYLDFLLSKIVLYKPFYHYISIDPLDIPEFQFQIHMAENCIEVAKKVIQLSYEMITQNLLSGSYWFSIHTIFFSVACLKFYVYQTEKGLIRNGKVDSDIHNATQLGSEILSLLKGASNASKRTFEVLNQLFKEFNEKTSVLSEQLLNIVKLQRQESSGALVPQLQTNNNFTKCQGELHHGQQHHQTPATSLRSILNLPQGEADLKFQNTNNESHTTTAAQEEYLDKLLAEFEEFDYSINRVLPDVIDFSALIGQDSSANNQIFSSEFSSDPTVN
SIO_010081: YJL206C
subclass of: SO_0000673
so part of: YJL206C
location: complement(47659..49935)
location: region:47659-49935:-1
so has part: feature:47659-49935:-1:exon

NP_012329.1
type: Protein
SIO_000068: ncbiprotein

S000003741
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:47659-49935:-1:exon

YJL205C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: NCE1
alternative label: YJL205C-A
alternative label: YJL206C-A
gene: NCE101
locus tag: YJL205C
gene synonym: NCE1; YJL205C-A; YJL206C-A
so part of: sequence
location: complement(<50139..>50443)
location: region:50139-50443:-1
so has part: feature:50139-50443:-1:exon
subclass of: SO_0000010

853225
type: Gene
SIO_000068: ncbigene

position:50139:-1
position: 50139
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:50443:-1
position: 50443
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:50139-50443:-1:exon

YJL205C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: NCE1
alternative label: YJL205C-A
alternative label: YJL206C-A
gene: NCE101
locus tag: YJL205C
gene synonym: NCE1; YJL205C-A; YJL206C-A
product: Nce101p
transcript id: NM_001181639.1
SIO_010081: YJL205C
subclass of: SO_0000673
so part of: YJL205C
location: complement(join(<50139..50268,50412..>50443))
location: region:50139-50443:-1
so has part: feature:50412-50443:-1:exon
so has part: feature:50139-50268:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:50412-50443:-1:exon

position:50412:-1
position: 50412
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:50139-50268:-1:exon

position:50268:-1
position: 50268
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YJL205C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: NCE1
alternative label: YJL205C-A
alternative label: YJL206C-A
gene: NCE101
locus tag: YJL205C
gene synonym: NCE1; YJL205C-A; YJL206C-A
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0009306 protein secretion [PMID:8655575]
note: hypothetical protein; involved in secretion of proteins that lack classical secretory signal sequences; SWAT-GFP and mCherry fusion proteins localize to the cytosol
codon start: 1
product: Nce101p
translation: MVQYAPFLLGKFSDPLLAIMVGCLSYYVYERKMGRPQGHHLHELIKKRWDDRK
SIO_010081: YJL205C
subclass of: SO_0000673
so part of: YJL205C
location: complement(join(50139..50268,50412..50443))
location: region:50139-50443:-1
so has part: feature:50412-50443:-1:exon
so has part: feature:50139-50268:-1:exon

NP_012330.1
type: Protein
SIO_000068: ncbiprotein

S000003742
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:50412-50443:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:50139-50268:-1:exon

YJL204C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RCY1
locus tag: YJL204C
so part of: sequence
location: complement(<50629..>53151)
location: region:50629-53151:-1
so has part: feature:50629-53151:-1:exon
subclass of: SO_0000010

853226
type: Gene
SIO_000068: ncbigene

position:50629:-1
position: 50629
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:53151:-1
position: 53151
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:50629-53151:-1:exon

YJL204C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RCY1
locus tag: YJL204C
product: Rcy1p
transcript id: NM_001181637.1
SIO_010081: YJL204C
subclass of: SO_0000673
so part of: YJL204C
location: complement(<50629..>53151)
location: region:50629-53151:-1
so has part: feature:50629-53151:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:50629-53151:-1:exon

YJL204C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RCY1
locus tag: YJL204C
experiment: EXISTENCE:direct assay:GO:0005768 endosome [PMID:15537705]
experiment: EXISTENCE:direct assay:GO:0005794 Golgi apparatus [PMID:15537705]
experiment: EXISTENCE:direct assay:GO:0005933 cellular bud [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0030427 site of polarized growth [PMID:11287615]
experiment: EXISTENCE:mutant phenotype:GO:0000149 SNARE binding [PMID:11287615]
experiment: EXISTENCE:mutant phenotype:GO:0006897 endocytosis [PMID:10769031|PMID:11378903]
experiment: EXISTENCE:mutant phenotype:GO:0032456 endocytic recycling [PMID:24272750]
experiment: EXISTENCE:mutant phenotype:GO:0034498 early endosome to Golgi transport [PMID:15537705]
note: F-box protein involved in recycling endocytosed proteins; involved in recycling plasma membrane proteins internalized by endocytosis; localized to sites of polarized growth; direct interaction with C-terminal cytoplasmic region of Drs2p plays an important role for Drs2p function in endocytic recycling pathway; required for turnover of histone H3 variant Cse4p
codon start: 1
product: Rcy1p
translation: MDDLLKVPEIVTNIASYLSTVDYLSFQQVNKRVYAIINGKNDSKYWSLKLTRMGLQQVHSNEEEEITLLDENDNQNSLRIFEIYKSFTAQNSKKIFVKFYRCYNSYARKLYNNNLANFFPTSYSNDPLKQTRILNFIKKYNFSNKNDIETFTRIETNFNILREIFINSVLKESELNYQSNNLAAVARFMKILLISNEESNAIEFFKSKADLPPSLTVLPSNDELFWAEQPREEDSGGSTVIFNSKNLDTFLNQLRDFLNEKIKLADILFKDEFPVILQFIESFIQDILLDILNNILLSYSEFLKENGKDSKANYECVPELYFTFIKKFDTELNDSVNAGANFRKVVRDLLNLYLEPFVVNYMNQTTRVFESLINSQLANYDTQVQDKQREQNAKIYNTLKDQTDASSASNNELPNDLSIITETSKTVPEADSKPSTIHQSVHSTDISNDKLDFLSSFTKIFKFSNNENQRLKQQLQLAYNLNLISNNLQNIKSLISLDLCYKILQETSEKTDQIYKFHTIESLLPLIKLRCQEIFKILITQLNKNHVKPAFEKAILLLQKYNPNEIEQIEIKFNSLSPANTQVEPLVQFTELINIGDIILQMISIFYKNELIPKKIIDKNKDFLNDVIQLKKNFETSIDDFVAEGLNIGINKLMDEISFVFKTLQLPDDYNPPPPSRNSPIRDIKPTKCAIRVVELLSNHCFLLTGATDKGTIDVYQQEIGERFFNEIVKHLKKCFISTEGAIWLICDLNYFYDFIANKLKQKNVVPYFVGLKSIGQLYIISGKDSKELGKLISDLGKFNGIFTQEEIYEFVQRRSDWVRVRKDVEKVMYGLGIRDCCIM
SIO_010081: YJL204C
subclass of: SO_0000673
so part of: YJL204C
location: complement(50629..53151)
location: region:50629-53151:-1
so has part: feature:50629-53151:-1:exon

NP_012331.1
type: Protein
SIO_000068: ncbiprotein

S000003740
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:50629-53151:-1:exon

YJL203W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SPP91
gene: PRP21
locus tag: YJL203W
gene synonym: SPP91
so part of: sequence
location: <53341..>54183
location: region:53341-54183:1
so has part: feature:53341-54183:1:exon
subclass of: SO_0000010

853227
type: Gene
SIO_000068: ncbigene

position:53341:1
position: 53341
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:54183:1
position: 54183
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:53341-54183:1:exon

YJL203W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SPP91
gene: PRP21
locus tag: YJL203W
gene synonym: SPP91
product: Prp21p
transcript id: NM_001181636.1
SIO_010081: YJL203W
subclass of: SO_0000673
so part of: YJL203W
location: <53341..>54183
location: region:53341-54183:1
so has part: feature:53341-54183:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:53341-54183:1:exon

YJL203W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SPP91
gene: PRP21
locus tag: YJL203W
gene synonym: SPP91
experiment: EXISTENCE:direct assay:GO:0000398 mRNA splicing, via spliceosome [PMID:8969185]
experiment: EXISTENCE:direct assay:GO:0003723 RNA binding [PMID:8065365]
experiment: EXISTENCE:direct assay:GO:0071004 U2-type prespliceosome [PMID:16618970]
note: Subunit of the SF3a splicing factor complex; required for spliceosome assembly
codon start: 1
product: Prp21p
translation: MEPEDTQLKEDIKTTVNYIKQHGVEFENKLLEDERFSFIKKDDPLHEYYTKLMNEPTDTVSGEDNDRKSEREIARPPDFLFSQYDTGISRRDMEVIKLTARYYAKDKSIVEQMISKDGEARLNFMNSSHPLHKTFTDFVAQYKRVYSFTGQEIKKSKRTILDNCFERTQYWEFEKDKDREHDKLVELCKIQFAAIPWDKFTQVAKFSIPEDTEIFEGSLDLEQMRLRRVQTGIKLFDSIKPTNEEEKIVSDQGKQKGGDSKGKKRKIRAVGETRLKKSKK
SIO_010081: YJL203W
subclass of: SO_0000673
so part of: YJL203W
location: 53341..54183
location: region:53341-54183:1
so has part: feature:53341-54183:1:exon

NP_012332.1
type: Protein
SIO_000068: ncbiprotein

S000003739
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:53341-54183:1:exon

YJL201W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ECM25
locus tag: YJL201W
so part of: sequence
location: <54379..>56178
location: region:54379-56178:1
so has part: feature:54379-56178:1:exon
subclass of: SO_0000010

853229
type: Gene
SIO_000068: ncbigene

position:54379:1
position: 54379
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:56178:1
position: 56178
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:54379-56178:1:exon

YJL201W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ECM25
locus tag: YJL201W
product: Ecm25p
transcript id: NM_001181634.1
SIO_010081: YJL201W
subclass of: SO_0000673
so part of: YJL201W
location: <54379..>56178
location: region:54379-56178:1
so has part: feature:54379-56178:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:54379-56178:1:exon

YJL201W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ECM25
locus tag: YJL201W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0042805 actinin binding [PMID:34010635]
experiment: EXISTENCE:mutant phenotype:GO:0051510 regulation of unidimensional cell growth [PMID:34010635]
experiment: EXISTENCE:mutant phenotype:GO:0080135 regulation of cellular response to stress [PMID:34010635]
note: Endocytic site protein required for stress-induced cell elongation; may link the polarization signal with the endocytic machinery to facilitate adaptive morphogenesis under conditions of stress; interacts with the polarity regulator Cdc42p, the SH3 domains of actin patch components and actin filaments; contains a Rho-GAP domain lacking the catalytic arginine finger, PXXP motifs and an xACT (F-actin binding) motif; promoter contains a consensus binding sequence for transcription factor Abf1p
codon start: 1
product: Ecm25p
translation: MIDINVNNIFFRSYSVDPNSGHAIYVFDSTYLPASDEIGDKQVYDLLINALMDRLVMKLPQAPYSLVIFSSGFSQRKISWVYGIKMFAKLPKETKFYLQKIFIVHESFFVRSVYQVISNAMNFNFLDSKDSQHDFPSLVHVLDLTSLSELIDITRLRISLNVYLYDYQIREHINVPEEYYNRLTPLAIRQYRQLVFDKIFKKLQNDALLCELIFQKPGNYKKVNIFLDIIKRNNYIDLSQWDIYSLASVWLNYFIKNKAKPLIPIELIPLPIVDDLKFTSETFRKIIKFNQYQDLFMVIIPFFNRIIAHGESTKHDSRTLSKALTPALCKEKLSMMTNDRLAIGSRYIKNLLDFFPEIAKEISSPPSSVSSSSTIPVLPKPRKSSPTRYSELGCLTLPRSRSPSPQRSVTSPTYTPVALQNTPVLKPKSSSRNVSSPSFNAKPPLPIKAVTRPQLSLTSNSNTDLALASSSTDTLSSPTKTPSADSLPLSNSSTDLTISDNIKEMVKDEPAKDKNSVETDIFVQQFESLTLVQNAKIKKFDKELQEKKKKNETTSKTADKFSQKGYSDIKASNKVSRLAALYEERLQGLQVMNEMKQRW
SIO_010081: YJL201W
subclass of: SO_0000673
so part of: YJL201W
location: 54379..56178
location: region:54379-56178:1
so has part: feature:54379-56178:1:exon

NP_012334.1
type: Protein
SIO_000068: ncbiprotein

S000003737
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:54379-56178:1:exon

YJL200C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ACO2
locus tag: YJL200C
so part of: sequence
location: complement(<56444..>58813)
location: region:56444-58813:-1
so has part: feature:56444-58813:-1:exon
subclass of: SO_0000010

853230
type: Gene
SIO_000068: ncbigene

position:56444:-1
position: 56444
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:58813:-1
position: 58813
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:56444-58813:-1:exon

YJL200C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ACO2
locus tag: YJL200C
product: aconitate hydratase ACO2
transcript id: NM_001181633.1
SIO_010081: YJL200C
subclass of: SO_0000673
so part of: YJL200C
location: complement(<56444..>58813)
location: region:56444-58813:-1
so has part: feature:56444-58813:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:56444-58813:-1:exon

YJL200C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ACO2
locus tag: YJL200C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:14562095|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:mutant phenotype:GO:0006099 tricarboxylic acid cycle [PMID:30834327]
note: Putative mitochondrial aconitase isozyme; similarity to Aco1p, an aconitase required for the TCA cycle; expression induced during growth on glucose, by amino acid starvation via Gcn4p, and repressed on ethanol
codon start: 1
product: aconitate hydratase ACO2
translation: MLSSANRFYIKRHLATHANMFPSVSKNFQTKVPPYAKLLTNLDKIKQITNNAPLTLAEKILYSHLCDPEESITSSDLSTIRGNKYLKLNPDRVAMQDASAQMALLQFMTTGLNQTSVPASIHCDHLIVGKDGETKDLPSSIATNQEVFDFLESCAKRYGIQFWGPGSGIIHQIVLENFSAPGLMMLGTDSHTPNAGGLGAIAIGVGGADAVDALTGTPWELKAPKILGVKLTGKLNGWSTPKDVITKLAGLLTVRGGTGYIVEYFGEGVSTLSCTGMATICNMGAEIGATTSTFPYQEAHKRYLQATNRAEVAEAADVALNKFNFLRADKDAQYDKVIEIDLSAIEPHVNGPFTPDLSTPISQYAEKSLKENWPQKVSAGLIGSCTNSSYQDMSRVVDLVKQASKAGLKPRIPFFVTPGSEQIRATLERDGIIDIFQENGAKVLANACGPCIGQWNREDVSKTSKETNTIFTSFNRNFRARNDGNRNTMNFLTSPEIVTAMSYSGDAQFNPLTDSIKLPNGKDFKFQPPKGDELPKRGFEHGRDKFYPEMDPKPDSNVEIKVDPNSDRLQLLEPFKPWNGKELKTNVLLKVEGKCTTDHISAAGVWLKYKGHLENISYNTLIGAQNKETGEVNKAYDLDGTEYDIPGLMMKWKSDGRPWTVIAEHNYGEGSAREHAALSPRFLGGEILLVKSFARIHETNLKKQGVLPLTFANESDYDKISSGDVLETLNLVDMIAKDGNNGGEIDVKITKPNGESFTIKAKHTMSKDQIDFFKAGSAINYIGNIRRNE
SIO_010081: YJL200C
subclass of: SO_0000673
so part of: YJL200C
location: complement(56444..58813)
location: region:56444-58813:-1
so has part: feature:56444-58813:-1:exon

NP_012335.1
type: Protein
SIO_000068: ncbiprotein

S000003736
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:56444-58813:-1:exon

YNCJ0001C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCJ0001C
so part of: sequence
location: complement(59100..59172)
location: region:59100-59172:-1
so has part: feature:59100-59172:-1:exon
subclass of: SO_0000663

853239
type: Gene
SIO_000068: ncbigene

position:59100:-1
position: 59100
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:59172:-1
position: 59172
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:59100-59172:-1:exon

YNCJ0001C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCJ0001C
product: tRNA-Thr
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Threonine tRNA (tRNA-Thr), predicted by tRNAscan-SE analysis
SIO_010081: YNCJ0001C
subclass of: SO_0000673
so part of: YNCJ0001C
location: complement(59100..59172)
location: region:59100-59172:-1
so has part: feature:59100-59172:-1:exon

S000006743
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:59100-59172:-1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 59505..59784
location: region:59505-59784:1
so has part: feature:59505-59784:1:region

S000007027
type: SGD
SIO_000068: sgd

position:59505:1
position: 59505
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:59784:1
position: 59784
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:59505-59784:1:region

YJL199C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MBB1
locus tag: YJL199C
so part of: sequence
location: complement(<59856..>60182)
location: region:59856-60182:-1
so has part: feature:59856-60182:-1:exon
subclass of: SO_0000010

853240
type: Gene
SIO_000068: ncbigene

position:59856:-1
position: 59856
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:60182:-1
position: 60182
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:59856-60182:-1:exon

YJL199C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MBB1
locus tag: YJL199C
product: Mbb1p
transcript id: NM_001348846.1
SIO_010081: YJL199C
subclass of: SO_0000673
so part of: YJL199C
location: complement(<59856..>60182)
location: region:59856-60182:-1
so has part: feature:59856-60182:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:59856-60182:-1:exon

YJL199C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MBB1
locus tag: YJL199C
note: hypothetical protein; conserved among S. cerevisiae strains, not conserved in closely related Saccharomyces species; protein detected via large-scale protein-protein interaction studies and enrichment-based proteogenomics; YJL199C is not an essential gene
codon start: 1
product: Mbb1p
translation: MYKVSACGVRIMSGISEIWIGELRDYKYALRLDREEYPAVLVYEYDSSSTRNYLFTIKYSDQRPNWQLITRDAALTAYDLLNRGGEFTTLSFPGATIHRSVSELSRLH
SIO_010081: YJL199C
subclass of: SO_0000673
so part of: YJL199C
location: complement(59856..60182)
location: region:59856-60182:-1
so has part: feature:59856-60182:-1:exon

NP_001335786.1
type: Protein
SIO_000068: ncbiprotein

S000003735
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:59856-60182:-1:exon

YJL198W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PHO90
locus tag: YJL198W
so part of: sequence
location: <60844..>63489
location: region:60844-63489:1
so has part: feature:60844-63489:1:exon
subclass of: SO_0000010

853241
type: Gene
SIO_000068: ncbigene

position:60844:1
position: 60844
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:63489:1
position: 63489
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:60844-63489:1:exon

YJL198W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PHO90
locus tag: YJL198W
product: SPX domain-containing inorganic phosphate transporter
transcript id: NM_001181631.1
SIO_010081: YJL198W
subclass of: SO_0000673
so part of: YJL198W
location: <60844..>63489
location: region:60844-63489:1
so has part: feature:60844-63489:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:60844-63489:1:exon

YJL198W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PHO90
locus tag: YJL198W
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:21143198]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0005315 inorganic phosphate transmembrane transporter activity [PMID:11779791]
experiment: EXISTENCE:genetic interaction:GO:0006817 phosphate ion transport [PMID:11779791]
experiment: EXISTENCE:genetic interaction:GO:2000185 regulation of phosphate transmembrane transport [PMID:12821119]
experiment: EXISTENCE:mutant phenotype:GO:0005315 inorganic phosphate transmembrane transporter activity [PMID:12581367]
experiment: EXISTENCE:mutant phenotype:GO:0006797 polyphosphate metabolic process [PMID:17804816]
note: Low-affinity phosphate transporter; acts upstream of Pho81p in regulation of the PHO pathway; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth; PHO90 has a paralog, PHO87, that arose from the whole genome duplication
codon start: 1
product: SPX domain-containing inorganic phosphate transporter
translation: MRFSHFLKYNAVPEWQNHYMDYSELKNLIYTLQTDELQVGDNEEGFGAGKSSNITDRFKNKFSFKNAKEDTSSGMNKDAGIVEETIELRELPTAQTVAAKPSPFRRMKEKIFYKRRSSSASSVSSTANENLQLDTYDTFVGDLTAEKQKVDDFYKRTEAKFYDKFDALVKDLKKIGVIEYDIDDDTLFNEPIASTNDEVPPLDLDDDEDDDEFYDDQSNIEDNTALLHHSQYNIKSQKKSLLKKSIVNLYIDLCQLKSFIELNRIGFAKITKKSDKVLHLNTRTELIESEQFFKDTYAFQAETIELLNSKISQLVTFYARITDRPHNISHSKQELKSYLHDHIVWERSNTWKDMLGLLSQADELTPKETEYNANKLVGKLDLEYYRWPLPRPINLKFTSINNVALPKLFFTKKAYKIYFIILVTGLLLGIKTFNDAAQHRCMALVECVAFLWASEAIPLHITAFLVPLLVVLFKVLKTSDGAIMSAASASSEILAAMWSSTIMILLAGFTLGEVLAQYNIAKVLASWLLAFAGCKPRNVLLMAMCVVFFLSMWISNVAAPVLTYSLLSPLLDAMDADSPFAQALVLGVALAANIGGMSSPISSPQNIISMSYLKPYGIGWGQFFAVALPSGILAMLLVWILLFTTFKMNKTKLEKFKPIKTKFTVKQYYIITVTVATILLWCVESQIEGAFGSSGQIAIIPIVLFFGTGLLSTQDLNAFPWSIVILAMGGIALGKAVSSSGLLSTIAKALQKKIENDGVFAILCIFGILMLVVGTFVSHTVSAIIIIPLVQEVGDKLGNPKAAPILVFGCALLSSCGMGLASSGFPNVTAISKVDRKGDRYLSVMTFLTRGVPASILAFLCVITLGYGIMASVVKGNATSA
SIO_010081: YJL198W
subclass of: SO_0000673
so part of: YJL198W
location: 60844..63489
location: region:60844-63489:1
so has part: feature:60844-63489:1:exon

NP_012337.1
type: Protein
SIO_000068: ncbiprotein

S000003734
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:60844-63489:1:exon

YJL197W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: UBP12
locus tag: YJL197W
so part of: sequence
location: <63805..>67569
location: region:63805-67569:1
so has part: feature:63805-67569:1:exon
subclass of: SO_0000010

853242
type: Gene
SIO_000068: ncbigene

position:63805:1
position: 63805
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:67569:1
position: 67569
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:63805-67569:1:exon

YJL197W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: UBP12
locus tag: YJL197W
product: putative ubiquitin-specific protease UBP12
transcript id: NM_001181630.1
SIO_010081: YJL197W
subclass of: SO_0000673
so part of: YJL197W
location: <63805..>67569
location: region:63805-67569:1
so has part: feature:63805-67569:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:63805-67569:1:exon

YJL197W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: UBP12
locus tag: YJL197W
EC number: 3.4.19.12
experiment: EXISTENCE:direct assay:GO:0004843 cysteine-type deubiquitinase activity [PMID:29309037]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0043596 nuclear replication fork [PMID:31665643]
experiment: EXISTENCE:genetic interaction:GO:0016579 protein deubiquitination [PMID:31665643]
experiment: EXISTENCE:genetic interaction:GO:2001020 regulation of response to DNA damage stimulus [PMID:31665643]
experiment: EXISTENCE:mutant phenotype:GO:0010637 negative regulation of mitochondrial fusion [PMID:23317502]
experiment: EXISTENCE:mutant phenotype:GO:0016579 protein deubiquitination [PMID:23317502|PMID:29309037]
note: Ubiquitin-specific protease; cleaves ubiquitin from ubiquitinated proteins; present in the nucleus and cytoplasm
codon start: 1
product: putative ubiquitin-specific protease UBP12
translation: MGSSDVSSRECSLVYNEDPDFTDGTTPCDRLGVDLMNVLDDKDEIKQESVPVSDREIEDTESDASAVSSFASANELIAEPHAASETNLGTNGQDGRNVLEQQRDVVARLIEENKETQKEGDKVCIVPKVWYDKFFDPDVTDPEDIGPINTRMICRDFENFVLEDYNRCPYLSIAEPVFNFLSEIYGMTSGSYPVVTNLVINQTTGELETEYNKWFFRLHYLTEKQDGRKRRHGQDDSIMYLSMSALNLVRDLVEKSMNLFFEKADHLDVNAVDFKIWFVSEGSDIATDSNVSTFLNSSYEITPLQFLELPIKKLLIPDMFENRLDKITSNPSDLVIEIKPIEGNHHWPSNYFAYNKLEPASGTTGLVNLGNTCYMNSALQCLVHIPQLRDYFLYDGYEDEINEENPLGYHGYVARAFSDLVQKLFQNRMSIMQRNAAFPPSMFKSTIGHFNSMFSGYMQQDSQEFLAFLLDSLHEDLNRIIKKEYTEKPSLSPGDDVNDWNVVKKLADDTWEMHLKRNCSVITDLFVGMYKSTLYCPECQNVSITFDPYNDVTLPLPVDTVWDKTIKIFPMNSPPLLLEVELSKSSTYMDLKNYVGKMSGLDPNTLFGCEIFSNQIYVNYESTESNAQFLTLQELIKPADDVIFYELPVTNDNEVIVPVLNTRIEKGYKNAMLFGVPFFITLKEDELNNPGAIRMKLQNRFVHLSGGYIPFPEPVGNRTDFADAFPLLVEKYPDVEFEQYKDILQYTSIKVTDKDKSFFSIKILSVEKEQQFASNNRTGPNFWTPISQLNLDKATDIDDKLEDVVKDIYNYSSLVDCAEGVLMQVDDEGDTEGSEAKNFSKPFQSGDDEENKETVTNNENVNNTNDRDEDMELTDDVEEDASTEPELTDKPEALDKIKDSLTSTPFAILSMNDIIVCEWSELGSNEAFSDDKIYNWENPATLPNKELENAKLERSNAKERTITLDDCLQLFSKPEILGLTDSWYCPTCKEHRQATKQIQLWNTPDILLIHLKRFESQRSFSDKIDATVNFPITDLDLSRYVVYKDDPRGLIYDLYAVDNHYGGLGGGHYTAYVKNFADNKWYYFDDSRVTETAPENSIAGSAYLLFYIRRHKDGNGLGSSKLQEIIQKSRHGYDERIKKIYDEQMKLYEFNKTDEEEDVSDDMIECNEDVQAPEYSNRSLEVGHIETQDCNDEDDNDDGERTNSGRRKLRLLKKVYKNNSGLGSSSTSEISEGCPENEVADLNLKNGVTLESPE
SIO_010081: YJL197W
subclass of: SO_0000673
so part of: YJL197W
location: 63805..67569
location: region:63805-67569:1
so has part: feature:63805-67569:1:exon

NP_012338.1
type: Protein
SIO_000068: ncbiprotein

S000003733
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:63805-67569:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1005; Autonomously Replicating Sequence
so part of: sequence
location: 67663..67736
location: region:67663-67736:1
so has part: feature:67663-67736:1:region

S000028442
type: SGD
SIO_000068: sgd

position:67663:1
position: 67663
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:67736:1
position: 67736
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:67663-67736:1:region

YJL196C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ELO1
locus tag: YJL196C
so part of: sequence
location: complement(<67850..>68782)
location: region:67850-68782:-1
so has part: feature:67850-68782:-1:exon
subclass of: SO_0000010

853243
type: Gene
SIO_000068: ncbigene

position:67850:-1
position: 67850
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:68782:-1
position: 68782
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:67850-68782:-1:exon

YJL196C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ELO1
locus tag: YJL196C
product: fatty acid elongase ELO1
transcript id: NM_001181629.1
SIO_010081: YJL196C
subclass of: SO_0000673
so part of: YJL196C
location: complement(<67850..>68782)
location: region:67850-68782:-1
so has part: feature:67850-68782:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:67850-68782:-1:exon

YJL196C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ELO1
locus tag: YJL196C
EC number: 2.3.1.199
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0009922 fatty acid elongase activity [PMID:12684876]
experiment: EXISTENCE:mutant phenotype:GO:0019368 fatty acid elongation, unsaturated fatty acid [PMID:10850979]
note: Elongase I, medium-chain acyl elongase; catalyzes carboxy-terminal elongation of unsaturated C12-C16 fatty acyl-CoAs to C16-C18 fatty acids; ELO1 has a paralog, ELO2, that arose from the whole genome duplication
codon start: 1
product: fatty acid elongase ELO1
translation: MVSDWKNFCLEKASRFRPTIDRPFFNIYLWDYFNRAVGWATAGRFQPKDFEFTVGKQPLSEPRPVLLFIAMYYVVIFGGRSLVKSCKPLKLRFISQVHNLMLTSVSFLWLILMVEQMLPIVYRHGLYFAVCNVESWTQPMETLYYLNYMTKFVEFADTVLMVLKHRKLTFLHTYHHGATALLCYNQLVGYTAVTWVPVTLNLAVHVLMYWYYFLSASGIRVWWKAWVTRLQIVQFMLDLIVVYYVLYQKIVAAYFKNACTPQCEDCLGSMTAIAAGAAILTSYLFLFISFYIEVYKRGSASGKKKINKNN
SIO_010081: YJL196C
subclass of: SO_0000673
so part of: YJL196C
location: complement(67850..68782)
location: region:67850-68782:-1
so has part: feature:67850-68782:-1:exon

NP_012339.1
type: Protein
SIO_000068: ncbiprotein

S000003732
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:67850-68782:-1:exon

YJL194W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CDC6
locus tag: YJL194W
so part of: sequence
location: <69338..>70879
location: region:69338-70879:1
so has part: feature:69338-70879:1:exon
subclass of: SO_0000010

853244
type: Gene
SIO_000068: ncbigene

position:69338:1
position: 69338
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:70879:1
position: 70879
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:69338-70879:1:exon

YJL194W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CDC6
locus tag: YJL194W
product: AAA family ATPase CDC6
transcript id: NM_001181627.1
SIO_010081: YJL194W
subclass of: SO_0000673
so part of: YJL194W
location: <69338..>70879
location: region:69338-70879:1
so has part: feature:69338-70879:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:69338-70879:1:exon

YJL194W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CDC6
locus tag: YJL194W
experiment: EXISTENCE:direct assay:GO:0003682 chromatin binding [PMID:9159120|PMID:9288745]
experiment: EXISTENCE:direct assay:GO:0003688 DNA replication origin binding [PMID:16824194|PMID:9288745]
experiment: EXISTENCE:direct assay:GO:0003924 GTPase activity [PMID:8083240]
experiment: EXISTENCE:direct assay:GO:0005524 ATP binding [PMID:8083240]
experiment: EXISTENCE:direct assay:GO:0005525 GTP binding [PMID:8083240]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005656 nuclear pre-replicative complex [PMID:16824194]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication [PMID:16824194]
experiment: EXISTENCE:direct assay:GO:0016887 ATP hydrolysis activity [PMID:8083240]
experiment: EXISTENCE:direct assay:GO:0031261 DNA replication preinitiation complex [PMID:9554851]
experiment: EXISTENCE:mutant phenotype:GO:0000082 G1/S transition of mitotic cell cycle [PMID:10075735]
experiment: EXISTENCE:mutant phenotype:GO:0003682 chromatin binding [PMID:10075735]
experiment: EXISTENCE:mutant phenotype:GO:0005524 ATP binding [PMID:10075735]
experiment: EXISTENCE:mutant phenotype:GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication [PMID:10075735|PMID:23376927|PMID:8538771|PMID:9335335]
experiment: EXISTENCE:mutant phenotype:GO:0030174 regulation of DNA-templated DNA replication initiation [PMID:9990508]
experiment: EXISTENCE:mutant phenotype:GO:0140530 MCM complex loading [PMID:29795547]
experiment: EXISTENCE:physical interaction:GO:0005515 protein binding [PMID:10075735|PMID:9312054]
note: Essential ATP-binding protein required for DNA replication; component of the pre-replicative complex (pre-RC) which requires ORC to associate with chromatin and is in turn required for Mcm2-7p DNA association; dual role as a mitotic cyclin-dependent kinase inhibitor, that binds to and inhibits Cdc28p/Clb2p along with Sic1p, contributing to mitotic exit; homologous to S. pombe Cdc18p; relocalizes from nucleus to cytoplasm upon DNA replication stress; degraded in response to plasma membrane stress
codon start: 1
product: AAA family ATPase CDC6
translation: MSAIPITPTKRIRRNLFDDAPATPPRPLKRKKLQFTDVTPESSPEKLQFGSQSIFLRTKALLQKSSELVNLNSSDGALPARTAEYEQVMNFLAKAISEHRSDSLYITGPPGTGKTAQLDMIIRQKFQSLPLSLSTPRSKDVLRHTNPNLQNLSWFELPDGRLESVAVTSINCISLGEPSSIFQKIFDSFQDLNGPTLQIKNMQHLQKFLEPYHKKTTFVVVLDEMDRLLHANTSETQSVRTILELFLLAKLPTVSFVLIGMANSLDMKDRFLSRLNLDRGLLPQTIVFQPYTAEQMYEIVIQKMSSLPTIIFQPMAIKFAAKKCAGNTGDLRKLFDVLRGSIEIYELEKRFLLSPTRGSLNSAQVPLTPTTSPVKKSYPEPQGKIGLNYIAKVFSKFVNNNSTRTRIAKLNIQQKLILCTIIQSLKLNSDATIDESFDHYIKAITKTDTLAPLQRNEFLEICTILETCGLVSIKKTKCKGKTKRFVDKIDVDLDMREFYDEMTKISILKPFLH
SIO_010081: YJL194W
subclass of: SO_0000673
so part of: YJL194W
location: 69338..70879
location: region:69338-70879:1
so has part: feature:69338-70879:1:exon

NP_012341.1
type: Protein
SIO_000068: ncbiprotein

S000003730
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:69338-70879:1:exon

YJL193W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJL193W
so part of: sequence
location: <71366..>72574
location: region:71366-72574:1
so has part: feature:71366-72574:1:exon
subclass of: SO_0000010

853246
type: Gene
SIO_000068: ncbigene

position:71366:1
position: 71366
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:72574:1
position: 72574
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:71366-72574:1:exon

YJL193W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJL193W
product: uncharacterized protein
transcript id: NM_001181626.1
SIO_010081: YJL193W
subclass of: SO_0000673
so part of: YJL193W
location: <71366..>72574
location: region:71366-72574:1
so has part: feature:71366-72574:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:71366-72574:1:exon

YJL193W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJL193W
note: hypothetical protein; predicted to encode a triose phosphate transporter subfamily member based on phylogenetic analysis; similar to YOR307C/SLY41; deletion mutant has a respiratory growth defect
codon start: 1
product: uncharacterized protein
translation: MFQQLSASIRHNAHIIFLCISWYFISSLASQVTKQVLTVCPLPLFLGEFQFIYTAVLAWFTCYIAYSFPGFYRIFPNGTFPEYYIDDRETSRAARKESKLSSLIIPPSKPILQTVLPLGLFQFVGKYFGHTATSLVPVSTVASIKTLSPMFILLLQKILKISTLKITLTLIFSLCTLVLGVWIIVQEDNRSPASSNELREFSKYGVICAMISMFIFVLQNIYGKTVFTYRSQTDESQSNSGFSRQESPLPLYEKLDEKLVAKKKPKSYDKLTLMIYISLVGFCLSFGWFITLEFPVLFRYFFQINSSSTVIKAFPVSLFLLNGTFHFIQAMITFHLLGEVSTLTYSIANLMKRFAIIAVSWVFIGRRITWLQVFGLVLNTLGLFLYERCTSQSKIKAKIRPE
SIO_010081: YJL193W
subclass of: SO_0000673
so part of: YJL193W
location: 71366..72574
location: region:71366-72574:1
so has part: feature:71366-72574:1:exon

NP_012342.1
type: Protein
SIO_000068: ncbiprotein

S000003729
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:71366-72574:1:exon

YJL192C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: EMC7
gene: SOP4
locus tag: YJL192C
gene synonym: EMC7
so part of: sequence
location: complement(<72710..>73414)
location: region:72710-73414:-1
so has part: feature:72710-73414:-1:exon
subclass of: SO_0000010

853247
type: Gene
SIO_000068: ncbigene

position:72710:-1
position: 72710
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:73414:-1
position: 73414
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:72710-73414:-1:exon

YJL192C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: EMC7
gene: SOP4
locus tag: YJL192C
gene synonym: EMC7
product: Sop4p
transcript id: NM_001181625.1
SIO_010081: YJL192C
subclass of: SO_0000673
so part of: YJL192C
location: complement(<72710..>73414)
location: region:72710-73414:-1
so has part: feature:72710-73414:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:72710-73414:-1:exon

YJL192C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: EMC7
gene: SOP4
locus tag: YJL192C
gene synonym: EMC7
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:12230471|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0016020 membrane [PMID:12230471]
experiment: EXISTENCE:mutant phenotype:GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport [PMID:12230471]
note: ER-membrane protein; subunit of evolutionarily conserved EMC (Endoplasmic Reticulum Membrane Complex) implicated in ERAD (ER-associated degradation) and proper assembly of multi-pass transmembrane (TM) proteins; EMC acts in yeast as an ER-mitochondria tether that interacts with outer membrane protein Tom5 of TOM (Translocase of the Mitochondrial Outer Membrane) complex; suppressor of pma1-7, deletion of SOP4 slows down export of wild-type Pma1p and Pma1-7 from the ER
codon start: 1
product: Sop4p
translation: MFSQIVLLLSAFIYVASATARRGTIKGRLDLAASNITGFVSTRTSFKLYQIGNFSTEYPYTSTTMFQDDEGNFEFANLPLNDGVNETTYYVMYPASMDFNLKPNRILIEFKNLENGTLQLNAFKNFFGREYFPSKDITYPEKLQSMKVHPYITVELLHKAPIRSYLQARNVSIFSTGIVGNILNSRWKLAGVITLIALVVFPIIVEKLDPETARAIREEAKRKQREKYAAVASK
SIO_010081: YJL192C
subclass of: SO_0000673
so part of: YJL192C
location: complement(72710..73414)
location: region:72710-73414:-1
so has part: feature:72710-73414:-1:exon

NP_012343.1
type: Protein
SIO_000068: ncbiprotein

S000003728
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:72710-73414:-1:exon

YJL191W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CRY2
gene: RPS14B
locus tag: YJL191W
gene synonym: CRY2
so part of: sequence
location: <73787..>74611
location: region:73787-74611:1
so has part: feature:73787-74611:1:exon
subclass of: SO_0000010

853248
type: Gene
SIO_000068: ncbigene

position:73787:1
position: 73787
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:74611:1
position: 74611
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:73787-74611:1:exon

YJL191W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CRY2
gene: RPS14B
locus tag: YJL191W
gene synonym: CRY2
product: ribosomal 40S subunit protein S14B
transcript id: NM_001181624.1
SIO_010081: YJL191W
subclass of: SO_0000673
so part of: YJL191W
location: join(<73787..73796,74205..>74611)
location: region:73787-74611:1
so has part: feature:73787-73796:1:exon
so has part: feature:74205-74611:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:73787-73796:1:exon

position:73796:1
position: 73796
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:74205-74611:1:exon

position:74205:1
position: 74205
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YJL191W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CRY2
gene: RPS14B
locus tag: YJL191W
gene synonym: CRY2
experiment: EXISTENCE:direct assay:GO:0032040 small-subunit processome [PMID:15590835]
experiment: EXISTENCE:direct assay:GO:0070181 small ribosomal subunit rRNA binding [PMID:9858605]
experiment: EXISTENCE:genetic interaction:GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:16246728]
experiment: EXISTENCE:mutant phenotype:GO:0000028 ribosomal small subunit assembly [PMID:2277060]
experiment: EXISTENCE:mutant phenotype:GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:15125836]
note: Protein component of the small (40S) ribosomal subunit; required for ribosome assembly and 20S pre-rRNA processing; mutations confer cryptopleurine resistance; homologous to mammalian ribosomal protein S14 and bacterial S11; RPS14B has a paralog, RPS14A, that arose from the whole genome duplication
codon start: 1
product: ribosomal 40S subunit protein S14B
translation: MANDLVQARDNSQVFGVARIYASFNDTFVHVTDLSGKETIARVTGGMKVKADRDESSPYAAMLAAQDVAAKCKEVGITAVHVKIRATGGTRTKTPGPGGQAALRALARSGLRIGRIEDVTPVPSDSTRKKGGRRGRRL
SIO_010081: YJL191W
subclass of: SO_0000673
so part of: YJL191W
location: join(73787..73796,74205..74611)
location: region:73787-74611:1
so has part: feature:73787-73796:1:exon
so has part: feature:74205-74611:1:exon

NP_012344.1
type: Protein
SIO_000068: ncbiprotein

S000003727
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:73787-73796:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:74205-74611:1:exon

YJL190C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RPS24
gene: RPS22A
locus tag: YJL190C
gene synonym: RPS24
so part of: sequence
location: complement(<74910..>75302)
location: region:74910-75302:-1
so has part: feature:74910-75302:-1:exon
subclass of: SO_0000010

853249
type: Gene
SIO_000068: ncbigene

position:74910:-1
position: 74910
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:75302:-1
position: 75302
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:74910-75302:-1:exon

YJL190C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RPS24
gene: RPS22A
locus tag: YJL190C
gene synonym: RPS24
product: ribosomal 40S subunit protein S22A
transcript id: NM_001181623.1
SIO_010081: YJL190C
subclass of: SO_0000673
so part of: YJL190C
location: complement(<74910..>75302)
location: region:74910-75302:-1
so has part: feature:74910-75302:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:74910-75302:-1:exon

YJL190C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RPS24
gene: RPS22A
locus tag: YJL190C
gene synonym: RPS24
experiment: EXISTENCE:curator inference:GO:0002181 cytoplasmic translation [PMID:6814480]
experiment: EXISTENCE:direct assay:GO:0003735 structural constituent of ribosome [PMID:6814480]
experiment: EXISTENCE:direct assay:GO:0022627 cytosolic small ribosomal subunit [PMID:6814480]
note: Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S15A and bacterial S8; RPS22A has a paralog, RPS22B, that arose from the whole genome duplication
codon start: 1
product: ribosomal 40S subunit protein S22A
translation: MTRSSVLADALNAINNAEKTGKRQVLIRPSSKVIIKFLQVMQKHGYIGEFEYIDDHRSGKIVVQLNGRLNKCGVISPRFNVKIGDIEKWTANLLPARQFGYVILTTSAGIMDHEEARRKHVSGKILGFVY
SIO_010081: YJL190C
subclass of: SO_0000673
so part of: YJL190C
location: complement(74910..75302)
location: region:74910-75302:-1
so has part: feature:74910-75302:-1:exon

NP_012345.1
type: Protein
SIO_000068: ncbiprotein

S000003726
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:74910-75302:-1:exon

YJL189W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RPL46
alternative label: SPB2
gene: RPL39
locus tag: YJL189W
gene synonym: RPL46; SPB2
so part of: sequence
location: <75933..>76474
location: region:75933-76474:1
so has part: feature:75933-76474:1:exon
subclass of: SO_0000010

853250
type: Gene
SIO_000068: ncbigene

position:75933:1
position: 75933
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:76474:1
position: 76474
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:75933-76474:1:exon

YJL189W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RPL46
alternative label: SPB2
gene: RPL39
locus tag: YJL189W
gene synonym: RPL46; SPB2
product: ribosomal 60S subunit protein L39
transcript id: NM_001181622.1
SIO_010081: YJL189W
subclass of: SO_0000673
so part of: YJL189W
location: join(<75933..75938,76325..>76474)
location: region:75933-76474:1
so has part: feature:75933-75938:1:exon
so has part: feature:76325-76474:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:75933-75938:1:exon

position:75938:1
position: 75938
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:76325-76474:1:exon

position:76325:1
position: 76325
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YJL189W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RPL46
alternative label: SPB2
gene: RPL39
locus tag: YJL189W
gene synonym: RPL46; SPB2
experiment: EXISTENCE:curator inference:GO:0002181 cytoplasmic translation [PMID:11983894]
experiment: EXISTENCE:curator inference:GO:0003735 structural constituent of ribosome [PMID:11983894]
experiment: EXISTENCE:direct assay:GO:0022625 cytosolic large ribosomal subunit [PMID:11983894]
note: Ribosomal 60S subunit protein L39; required for ribosome biogenesis; loss of both Rpl31p and Rpl39p confers lethality; also exhibits genetic interactions with SIS1 and PAB1; homologous to mammalian ribosomal protein L39, no bacterial homolog
codon start: 1
product: ribosomal 60S subunit protein L39
translation: MAAQKSFRIKQKMAKAKKQNRPLPQWIRLRTNNTIRYNAKRRNWRRTKMNI
SIO_010081: YJL189W
subclass of: SO_0000673
so part of: YJL189W
location: join(75933..75938,76325..76474)
location: region:75933-76474:1
so has part: feature:75933-75938:1:exon
so has part: feature:76325-76474:1:exon

NP_012346.1
type: Protein
SIO_000068: ncbiprotein

S000003725
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:75933-75938:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:76325-76474:1:exon

YJL187C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: WEE1
gene: SWE1
locus tag: YJL187C
gene synonym: WEE1
so part of: sequence
location: complement(<76803..>79262)
location: region:76803-79262:-1
so has part: feature:76803-79262:-1:exon
subclass of: SO_0000010

853252
type: Gene
SIO_000068: ncbigene

position:76803:-1
position: 76803
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:79262:-1
position: 79262
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:76803-79262:-1:exon

YJL187C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: WEE1
gene: SWE1
locus tag: YJL187C
gene synonym: WEE1
product: tyrosine protein kinase SWE1
transcript id: NM_001181620.1
SIO_010081: YJL187C
subclass of: SO_0000673
so part of: YJL187C
location: complement(<76803..>79262)
location: region:76803-79262:-1
so has part: feature:76803-79262:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:76803-79262:-1:exon

YJL187C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: WEE1
gene: SWE1
locus tag: YJL187C
gene synonym: WEE1
EC number: 2.7.11.1
experiment: EXISTENCE:direct assay:GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity [PMID:8253069]
experiment: EXISTENCE:direct assay:GO:0000086 G2/M transition of mitotic cell cycle [PMID:8253069]
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:16319894]
experiment: EXISTENCE:direct assay:GO:0004713 protein tyrosine kinase activity [PMID:8253069]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:10805747|PMID:15282802]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:10805747|PMID:15282802]
experiment: EXISTENCE:direct assay:GO:0044879 mitotic morphogenesis checkpoint signaling [PMID:8930890]
experiment: EXISTENCE:genetic interaction:GO:0000320 re-entry into mitotic cell cycle [PMID:15107621]
experiment: EXISTENCE:genetic interaction:GO:0010697 negative regulation of mitotic spindle pole body separation [PMID:8887667]
experiment: EXISTENCE:genetic interaction:GO:0090154 positive regulation of sphingolipid biosynthetic process [PMID:26634277]
experiment: EXISTENCE:mutant phenotype:GO:0000086 G2/M transition of mitotic cell cycle [PMID:8253069]
experiment: EXISTENCE:mutant phenotype:GO:0008361 regulation of cell size [PMID:12089449]
experiment: EXISTENCE:mutant phenotype:GO:0010697 negative regulation of mitotic spindle pole body separation [PMID:8887667]
experiment: EXISTENCE:mutant phenotype:GO:0040020 regulation of meiotic nuclear division [PMID:10619027]
experiment: EXISTENCE:mutant phenotype:GO:0044879 mitotic morphogenesis checkpoint signaling [PMID:9744879]
experiment: EXISTENCE:mutant phenotype:GO:0090154 positive regulation of sphingolipid biosynthetic process [PMID:26634277]
note: Protein kinase that regulates the G2/M transition; negative regulator of the Cdc28p kinase; morphogenesis checkpoint kinase; positive regulator of sphingolipid biosynthesis via Orm2p; phosphorylates a tyrosine residue in the N-terminus of Hsp90 in a cell-cycle associated manner, thus modulating the ability of Hsp90 to chaperone a selected clientele; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate
codon start: 1
product: tyrosine protein kinase SWE1
translation: MSSLDEDEEDFEMLDTENLQFMGKKMFGKQAGEDESDDFAIGGSTPTNKLKFYPYSNNKLTRSTGTLNLSLSNTALSEANSKFLGKIEEEEEEEEEGKDEESVDSRIKRWSPFHENESVTTPITKRSAEKTNSPISLKQWNQRWFPKNDARTENTSSSSSYSVAKPNQSAFTSSGLVSKMSMDTSLYPAKLRIPETPVKKSPLVEGRDHKHVHLSSSKNASSSLSVSPLNFVEDNNLQEDLLFSDSPSSKALPSIHVPTIDSSPLSEAKYHAHDRHNNQTNILSPTNSLVTNSSPQTLHSNKFKKIKRARNSVILKNRELTNSLQQFKDDLYGTDENFPPPIIISSHHSTRKNPQPYQFRGRYDNDTDEEISTPTRRKSIIGATSQTHRESRPLSLSSAIVTNTTSAETHSISSTDSSPLNSKRRLISSNKLSANPDSHLFEKFTNVHSIGKGQFSTVYQVTFAQTNKKYAIKAIKPNKYNSLKRILLEIKILNEVTNQITMDQEGKEYIIDYISSWKFQNSYYIMTELCENGNLDGFLQEQVIAKKKRLEDWRIWKIIVELSLALRFIHDSCHIVHLDLKPANVMITFEGNLKLGDFGMATHLPLEDKSFENEGDREYIAPEIISDCTYDYKADIFSLGLMIVEIAANVVLPDNGNAWHKLRSGDLSDAGRLSSTDIHSESLFSDITKVDTNDLFDFERDNISGNSNNAGTSTVHNNSNINNPNMNNGNDNNNVNTAATKNRLILHKSSKIPAWVPKFLIDGESLERIVRWMIEPNYERRPTANQILQTEECLYVEMTRNAGAIIQEDDFGPKPKFFI
SIO_010081: YJL187C
subclass of: SO_0000673
so part of: YJL187C
location: complement(76803..79262)
location: region:76803-79262:-1
so has part: feature:76803-79262:-1:exon

NP_012348.1
type: Protein
SIO_000068: ncbiprotein

S000003723
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:76803-79262:-1:exon

YJL186W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MNN5
locus tag: YJL186W
so part of: sequence
location: <80155..>81915
location: region:80155-81915:1
so has part: feature:80155-81915:1:exon
subclass of: SO_0000010

853253
type: Gene
SIO_000068: ncbigene

position:80155:1
position: 80155
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:81915:1
position: 81915
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:80155-81915:1:exon

YJL186W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MNN5
locus tag: YJL186W
product: alpha-1,2-mannosyltransferase MNN5
transcript id: NM_001181619.2
SIO_010081: YJL186W
subclass of: SO_0000673
so part of: YJL186W
location: <80155..>81915
location: region:80155-81915:1
so has part: feature:80155-81915:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:80155-81915:1:exon

YJL186W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MNN5
locus tag: YJL186W
experiment: EXISTENCE:direct assay:GO:0005794 Golgi apparatus [PMID:9756928]
experiment: EXISTENCE:mutant phenotype:GO:0000026 alpha-1,2-mannosyltransferase activity [PMID:9756928]
experiment: EXISTENCE:mutant phenotype:GO:0006486 protein glycosylation [PMID:9756928]
note: Alpha-1,2-mannosyltransferase; responsible for addition of the second alpha-1,2-linked mannose of the branches on the mannan backbone of oligosaccharides, localizes to an early Golgi compartment
codon start: 1
product: alpha-1,2-mannosyltransferase MNN5
translation: MLIRLKKRKILQVIVSAVVLILFFCSVHNDVSSSWLYGKKLRLPVLTRSNLKNNFYTTLVQAIVENKPADSSPDLSKLHGAEGCSFANNVAAHDSGHDSDLSYESLSKCYNLNKTVQESLREVHSKFTDTLSGKLNFSIPQREALFSGSEGIVTIGGGKYSVLAYTMIKKLRDTGTTLPIEVIIPPQDEGEDDFCKNWLPKFNGKCIYFSDIVPSKPLSDLKLTHFQLKVFGLIISSFKRIIFLDADNYAVKNLDLAFNTTSFNDTGLILWPDFWRRVTPPAFYNIIGSSINIGKRVRFVSDDISPVSRYDPFVSNSNDYTPKERQEHFLKHVPLHDLDGTMPDLSSESGQMVIDKIRHFNTLLLALYYNVYGPTWYYKMISQGTAGEGDKDTFVAAAHALNMPYYQVRTNFEFDGFFYQKDDYKGLALLQHDFEQDYKQYQKAQQKVKANIEEFSKLDPDYTLDNGFLKTLMVNDDGSDLDIMFIHASFYKADPWTLYHENRFIGPNGEQVRGFRKPHRYGMDFELFLFNDMRGSFCTTPKSQVIKFKYFTDKVNTPEWDAMCEYLTNHVNYLESTHKEAMGEKN
SIO_010081: YJL186W
subclass of: SO_0000673
so part of: YJL186W
location: 80155..81915
location: region:80155-81915:1
so has part: feature:80155-81915:1:exon

NP_012349.2
type: Protein
SIO_000068: ncbiprotein

S000003722
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:80155-81915:1:exon

YJL185C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ATG36
locus tag: YJL185C
so part of: sequence
location: complement(<82095..>82976)
location: region:82095-82976:-1
so has part: feature:82095-82976:-1:exon
subclass of: SO_0000010

853254
type: Gene
SIO_000068: ncbigene

position:82095:-1
position: 82095
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:82976:-1
position: 82976
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:82095-82976:-1:exon

YJL185C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ATG36
locus tag: YJL185C
product: Atg36p
transcript id: NM_001181618.1
SIO_010081: YJL185C
subclass of: SO_0000673
so part of: YJL185C
location: complement(<82095..>82976)
location: region:82095-82976:-1
so has part: feature:82095-82976:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:82095-82976:-1:exon

YJL185C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ATG36
locus tag: YJL185C
experiment: EXISTENCE:direct assay:GO:0005777 peroxisome [PMID:22643220]
experiment: EXISTENCE:mutant phenotype:GO:0000423 mitophagy [PMID:29673596]
experiment: EXISTENCE:mutant phenotype:GO:0030242 autophagy of peroxisome [PMID:22643220]
experiment: EXISTENCE:physical interaction:GO:0030242 autophagy of peroxisome [PMID:22643220]
note: Pex3p interacting protein, required for pexophagy; interacts with Atg8p and Atg11p; mRNA is weakly cell cycle regulated, peaking in G2 phase; YJL185C is a non-essential gene
codon start: 1
product: Atg36p
translation: MASVNNYQVDCGSRSARIQPRINNGIHDEESLFEVLELSEEEFELDFHRLKSFNDVRVINNPDLSPECTNTAISRDETLESASSAFEVPSDEIAILSISSDSNKNSPPSEQPAPALRNIRSSSNSDRIDEWCLGSHLFNELHQNVPQSSDGVNHGFPVYSFKERELYTSAKLKKLTNAQRIAVQKLSRDLYPILRTCYREKTRRQLLTYHHERIFDDIPSFFPQRDFIFNYYSMPLEFDRLSDVDIDSSSRSRFTDESTGETLNRSPSAASSSLENTSWFGWTLLSRFLDREW
SIO_010081: YJL185C
subclass of: SO_0000673
so part of: YJL185C
location: complement(82095..82976)
location: region:82095-82976:-1
so has part: feature:82095-82976:-1:exon

NP_012350.1
type: Protein
SIO_000068: ncbiprotein

S000003721
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:82095-82976:-1:exon

YJL184W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LDB6
alternative label: PCC2
gene: GON7
locus tag: YJL184W
gene synonym: LDB6; PCC2
so part of: sequence
location: <83448..>83819
location: region:83448-83819:1
so has part: feature:83448-83819:1:exon
subclass of: SO_0000010

853255
type: Gene
SIO_000068: ncbigene

position:83448:1
position: 83448
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:83819:1
position: 83819
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:83448-83819:1:exon

YJL184W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LDB6
alternative label: PCC2
gene: GON7
locus tag: YJL184W
gene synonym: LDB6; PCC2
product: chromatin DNA-binding EKC/KEOPS complex subunit GON7
transcript id: NM_001181617.1
SIO_010081: YJL184W
subclass of: SO_0000673
so part of: YJL184W
location: <83448..>83819
location: region:83448-83819:1
so has part: feature:83448-83819:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:83448-83819:1:exon

YJL184W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LDB6
alternative label: PCC2
gene: GON7
locus tag: YJL184W
gene synonym: LDB6; PCC2
experiment: EXISTENCE:direct assay:GO:0000408 EKC/KEOPS complex [PMID:16564010|PMID:16874308]
experiment: EXISTENCE:direct assay:GO:0000785 chromatin [PMID:16874308]
experiment: EXISTENCE:direct assay:GO:0031490 chromatin DNA binding [PMID:16874308]
experiment: EXISTENCE:genetic interaction:GO:0000722 telomere maintenance via recombination [PMID:23390378]
experiment: EXISTENCE:mutant phenotype:GO:0000032 cell wall mannoprotein biosynthetic process [PMID:14734024]
experiment: EXISTENCE:mutant phenotype:GO:0000723 telomere maintenance [PMID:16564010]
experiment: EXISTENCE:physical interaction:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:16874308]
note: Component of the EKC/KEOPS protein complex; EKC/KEOPS complex is required for t6A tRNA modification and telomeric TG1-3 recombination; may have role in transcription; implicated in osmotic stress response; other complex members are Kae1p, Cgi121p, Pcc1p, and Bud32p
codon start: 1
product: chromatin DNA-binding EKC/KEOPS complex subunit GON7
translation: MKLPVAQYSAPDGVEKSFAPIRDDPRYMTTEGRTTGPSDHVLNAGQIDRDKPSEPERTKDGSQLTYLGQLRTQLTGLQDDINEFLTGRMELAKNKKKAGADEKRIQEEINQLLDGGDGDEDAV
SIO_010081: YJL184W
subclass of: SO_0000673
so part of: YJL184W
location: 83448..83819
location: region:83448-83819:1
so has part: feature:83448-83819:1:exon

NP_012351.1
type: Protein
SIO_000068: ncbiprotein

S000003720
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:83448-83819:1:exon

YJL183W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MNN11
locus tag: YJL183W
so part of: sequence
location: <84068..>85336
location: region:84068-85336:1
so has part: feature:84068-85336:1:exon
subclass of: SO_0000010

853256
type: Gene
SIO_000068: ncbigene

position:84068:1
position: 84068
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:85336:1
position: 85336
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:84068-85336:1:exon

YJL183W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MNN11
locus tag: YJL183W
product: alpha-1,6-mannosyltransferase
transcript id: NM_001181616.2
SIO_010081: YJL183W
subclass of: SO_0000673
so part of: YJL183W
location: <84068..>85336
location: region:84068-85336:1
so has part: feature:84068-85336:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:84068-85336:1:exon

YJL183W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MNN11
locus tag: YJL183W
experiment: EXISTENCE:direct assay:GO:0000009 alpha-1,6-mannosyltransferase activity [PMID:10635561]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0006486 protein glycosylation [PMID:10635561]
experiment: EXISTENCE:mutant phenotype:GO:0006486 protein glycosylation [PMID:10635561]
experiment: EXISTENCE:mutant phenotype:GO:0006487 protein N-linked glycosylation [PMID:23210626]
experiment: EXISTENCE:physical interaction:GO:0000136 mannan polymerase complex [PMID:9430634]
note: Subunit of a Golgi mannosyltransferase complex; this complex also contains Anp1p, Mnn9p, Mnn10p, and Hoc1p, and mediates elongation of the polysaccharide mannan backbone; has homology to Mnn10p
codon start: 1
product: alpha-1,6-mannosyltransferase
translation: MAIKPRTKGKTYSSRSVGSQWFNRLGFKQNKYGTCKFLSIITAFVFILYFFSNRFYPISRSAGASYSPSHGLYINEIPASSRLIYPHVEHVPVLKQMTVRGLYITRLEVDGSKRLILKPEENALTDEEKKKTTDQILLVKHSFLDHGKLVYRKSNDAPEVVVVTLIDFENYELETIIQIVQNRVDYAQKHQYGVYIRWIQEFLPVLENQNLAESYEFIKPLVIRAAMHAFPTAKYIHFVDQDALLMNLDLSLQKYLLDPKIMDLALLKNVPVVANSNIKTYNHFEYSSAKIIIPHDADGNIDASSFVIANDFYGKALIDYLNDPLLRNFPWDNTGDKLSAAIGHILQWHPTLLGKTAIVIPKVLASQYDASLDQEGESGNGASNGDVYHYNEGDLAASFKGCRSRGTCASEIGHMYQKIKKS
SIO_010081: YJL183W
subclass of: SO_0000673
so part of: YJL183W
location: 84068..85336
location: region:84068-85336:1
so has part: feature:84068-85336:1:exon

NP_012352.2
type: Protein
SIO_000068: ncbiprotein

S000003719
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:84068-85336:1:exon

YJL181W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RBH1
locus tag: YJL181W
so part of: sequence
location: <85660..>87495
location: region:85660-87495:1
so has part: feature:85660-87495:1:exon
subclass of: SO_0000010

853257
type: Gene
SIO_000068: ncbigene

position:85660:1
position: 85660
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:87495:1
position: 87495
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:85660-87495:1:exon

YJL181W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RBH1
locus tag: YJL181W
product: Rbh1p
transcript id: NM_001181614.1
SIO_010081: YJL181W
subclass of: SO_0000673
so part of: YJL181W
location: <85660..>87495
location: region:85660-87495:1
so has part: feature:85660-87495:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:85660-87495:1:exon

YJL181W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RBH1
locus tag: YJL181W
note: hypothetical protein; expression is cell-cycle regulated as shown by microarray analysis; potential regulatory target of Mbp1p, which binds to the YJL181W promoter region; contains a PH-like domain; RBH1 has a paralog, RBH2, that arose from the whole genome duplication
codon start: 1
product: Rbh1p
translation: MEIFKEEEEEAFSAIEGIIYACEVYDPVPRHLHKSKTKIINAAKLIIETHLSYYTILNNISDIQAYLSTWLRDLGTTGPYQTILSESISLMFDRTVSIFRKCTIEGGFPHLIARLYLRLKSYQKLLNDAGLKNFFSSYDYAFGVAYNLVNCSEYRYDEVHYISNGTYSLVASMKIDPAEVIKREHFRLTIPKFNISNILIEIFHLLDGLAFFKVNPDSLSISTASAETIFRSISEGNHQVLELGRSLMFPLLRTGDFEICRIDDAGAVITFTEAKDVKLEIISLDEVSWVMQWKSCLQNYERRAANDSSFIKTHLQFKKANNFNEDNNGLGLIVDRNIPTDDFTLASTNRQSPPPSNTGCSLHRSKPLHIPLSSVIREDFYDSSLNERISKDGDSSCESFSGAESILSDYDFHDNEFFNNQSPHYFSEHIDNNSREVVITDENTIISLENTQVSRWSNYSWQKISPHQLQVSIIQLRMGNFIVAYDSDYNLHQFKIRLCDDIKCIQSTEQDIQIRVPLGAIMCSVTGILNIRTKDADKLLRVLSFYTTDHTEAVSHSNNQDATASPLSSVSSAMDLKHSLQKCSSTIMPQELTQDVIGSKSDLISNIRQKI
SIO_010081: YJL181W
subclass of: SO_0000673
so part of: YJL181W
location: 85660..87495
location: region:85660-87495:1
so has part: feature:85660-87495:1:exon

NP_012354.1
type: Protein
SIO_000068: ncbiprotein

S000003717
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:85660-87495:1:exon

YJL180C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ATP12
locus tag: YJL180C
so part of: sequence
location: complement(<87583..>88560)
location: region:87583-88560:-1
so has part: feature:87583-88560:-1:exon
subclass of: SO_0000010

853259
type: Gene
SIO_000068: ncbigene

position:87583:-1
position: 87583
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:88560:-1
position: 88560
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:87583-88560:-1:exon

YJL180C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ATP12
locus tag: YJL180C
product: ATP synthase complex assembly protein ATP12
transcript id: NM_001181613.1
SIO_010081: YJL180C
subclass of: SO_0000673
so part of: YJL180C
location: complement(<87583..>88560)
location: region:87583-88560:-1
so has part: feature:87583-88560:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:87583-88560:-1:exon

YJL180C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ATP12
locus tag: YJL180C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:1826907|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:mutant phenotype:GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly [PMID:2142305]
experiment: EXISTENCE:physical interaction:GO:0019904 protein domain specific binding [PMID:10747017]
experiment: EXISTENCE:physical interaction:GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly [PMID:10747017]
note: Assembly factor for F1 sector of mitochondrial F1F0 ATP synthase; conserved protein; required for assembly of alpha and beta subunits into F1 sector of mitochondrial F1F0 ATP synthase; human homolog ATPAF2 can complement yeast atp12 mutant; mutation of human homolog reduces active ATP synthase levels and is associated with the disorder ATPAF2 deficiency
codon start: 1
product: ATP synthase complex assembly protein ATP12
translation: MLPSLRKGCFIVNSIRLKLPRFYSLNAQPLGTDNTIENNTPTETNRLSKTSQKFWEKVSLNRDVEKGKIALQLDGRTIKTPLGNGIIVDNAKSLLAYLLKLEWSSLSSLSIKTHSLPLTSLVARCIDLQMTNEPGCDPQLVAKIGGNSDVIKNQLLRYLDTDTLLVFSPMNEFEGRLRNAQNELYIPIIKGMEEFLRNFSSESNIRLQILDADIHGLRGNQQSDIVKNAAKKYMSSLSPWDLAILEKTVLTTKSFICGVLLLENKKDTANLIPALKTDMDNIVRAATLETIFQVEKWGEVEDTHDVDKRDIRRKIHTAAIAAFKQ
SIO_010081: YJL180C
subclass of: SO_0000673
so part of: YJL180C
location: complement(87583..88560)
location: region:87583-88560:-1
so has part: feature:87583-88560:-1:exon

NP_012355.1
type: Protein
SIO_000068: ncbiprotein

S000003716
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:87583-88560:-1:exon

YJL179W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: GIM6
gene: PFD1
locus tag: YJL179W
gene synonym: GIM6
so part of: sequence
location: <88787..>89116
location: region:88787-89116:1
so has part: feature:88787-89116:1:exon
subclass of: SO_0000010

853260
type: Gene
SIO_000068: ncbigene

position:88787:1
position: 88787
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:89116:1
position: 89116
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:88787-89116:1:exon

YJL179W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: GIM6
gene: PFD1
locus tag: YJL179W
gene synonym: GIM6
product: prefolding complex chaperone subunit
transcript id: NM_001181612.2
SIO_010081: YJL179W
subclass of: SO_0000673
so part of: YJL179W
location: <88787..>89116
location: region:88787-89116:1
so has part: feature:88787-89116:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:88787-89116:1:exon

YJL179W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: GIM6
gene: PFD1
locus tag: YJL179W
gene synonym: GIM6
experiment: EXISTENCE:genetic interaction:GO:0032968 positive regulation of transcription elongation by RNA polymerase II [PMID:24068951]
experiment: EXISTENCE:mutant phenotype:GO:0006457 protein folding [PMID:9630229]
experiment: EXISTENCE:mutant phenotype:GO:0007010 cytoskeleton organization [PMID:9630229]
experiment: EXISTENCE:mutant phenotype:GO:0016272 prefoldin complex [PMID:9630229]
experiment: EXISTENCE:mutant phenotype:GO:0032968 positive regulation of transcription elongation by RNA polymerase II [PMID:24068951]
experiment: EXISTENCE:mutant phenotype:GO:0051082 unfolded protein binding [PMID:9630229]
note: Subunit of heterohexameric prefoldin; prefoldin binds cytosolic chaperonin and transfers target proteins to it; involved in the biogenesis of actin and of alpha- and gamma-tubulin; prefoldin complex also localizes to chromatin of actively transcribed genes in the nucleus and facilitates transcriptional elongation
codon start: 1
product: prefolding complex chaperone subunit
translation: MSQIAQEMTVSLRNARTQLDMVNQQLAYLDRQEKLAELTKKELESYPTDKVWRSCGKSFILQDKSKYVNDLSHDETVLLDQRKTLKIKKNYLETTVEKTIDNLKALMKN
SIO_010081: YJL179W
subclass of: SO_0000673
so part of: YJL179W
location: 88787..89116
location: region:88787-89116:1
so has part: feature:88787-89116:1:exon

NP_012356.2
type: Protein
SIO_000068: ncbiprotein

S000003715
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:88787-89116:1:exon

YJL178C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ETF1
gene: ATG27
locus tag: YJL178C
gene synonym: ETF1
so part of: sequence
location: complement(<89282..>90097)
location: region:89282-90097:-1
so has part: feature:89282-90097:-1:exon
subclass of: SO_0000010

853261
type: Gene
SIO_000068: ncbigene

position:89282:-1
position: 89282
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:90097:-1
position: 90097
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:89282-90097:-1:exon

YJL178C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ETF1
gene: ATG27
locus tag: YJL178C
gene synonym: ETF1
product: Atg27p
transcript id: NM_001181611.1
SIO_010081: YJL178C
subclass of: SO_0000673
so part of: YJL178C
location: complement(<89282..>90097)
location: region:89282-90097:-1
so has part: feature:89282-90097:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:89282-90097:-1:exon

YJL178C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ETF1
gene: ATG27
locus tag: YJL178C
gene synonym: ETF1
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0000407 phagophore assembly site [PMID:17135291]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:17135291]
experiment: EXISTENCE:direct assay:GO:0005774 vacuolar membrane [PMID:25557545]
experiment: EXISTENCE:direct assay:GO:0005802 trans-Golgi network [PMID:16107716]
experiment: EXISTENCE:direct assay:GO:0016020 membrane [PMID:12186856]
experiment: EXISTENCE:direct assay:GO:0016236 macroautophagy [PMID:25557545]
experiment: EXISTENCE:direct assay:GO:0032266 phosphatidylinositol-3-phosphate binding [PMID:12186856]
experiment: EXISTENCE:mutant phenotype:GO:0000045 autophagosome assembly [PMID:17135291]
experiment: EXISTENCE:mutant phenotype:GO:0016050 vesicle organization [PMID:12186856]
experiment: EXISTENCE:mutant phenotype:GO:0030242 autophagy of peroxisome [PMID:17135291]
experiment: EXISTENCE:mutant phenotype:GO:0032258 cytoplasm to vacuole transport by the Cvt pathway [PMID:17135291]
experiment: EXISTENCE:mutant phenotype:GO:0034497 protein localization to phagophore assembly site [PMID:17135291]
note: Type I membrane protein involved in autophagy and the Cvt pathway; targeted to vacuole via AP-3 pathway
codon start: 1
product: Atg27p
translation: MVSKTWICGFISIITVVQALSCEKHDVLKKYQVGKFSSLTSTERDTPPSTTIEKWWINVCEEHNVEPPEECKKNDMLCGLTDVILPGKDAITTQIIDFDKNIGFNVEETESALTLTLKGATWGANSFDAKLEFQCNDNMKQDELTSHTWADKSIQLTLKGPSGCLKSKDDDKKNGDGDNGKDGDSEGKKPAKKAGGTSWFTWLFLYALLFTLIYLMVVSFLNTRGGSFQDFRAEFIQRSTQFLTSLPEFCKEVVSRILGRSTAQRGGYSAV
SIO_010081: YJL178C
subclass of: SO_0000673
so part of: YJL178C
location: complement(89282..90097)
location: region:89282-90097:-1
so has part: feature:89282-90097:-1:exon

NP_012357.2
type: Protein
SIO_000068: ncbiprotein

S000003714
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:89282-90097:-1:exon

YJL177W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RPL17B
locus tag: YJL177W
so part of: sequence
location: <90786..>91657
location: region:90786-91657:1
so has part: feature:90786-91657:1:exon
subclass of: SO_0000010

853262
type: Gene
SIO_000068: ncbigene

position:90786:1
position: 90786
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:91657:1
position: 91657
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:90786-91657:1:exon

YJL177W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RPL17B
locus tag: YJL177W
product: ribosomal 60S subunit protein L17B
transcript id: NM_001181610.1
SIO_010081: YJL177W
subclass of: SO_0000673
so part of: YJL177W
location: join(<90786..91094,91412..>91657)
location: region:90786-91657:1
so has part: feature:90786-91094:1:exon
so has part: feature:91412-91657:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:90786-91094:1:exon

position:91094:1
position: 91094
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:91412-91657:1:exon

position:91412:1
position: 91412
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YJL177W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RPL17B
locus tag: YJL177W
experiment: EXISTENCE:direct assay:GO:0002181 cytoplasmic translation [PMID:18782943]
experiment: EXISTENCE:direct assay:GO:0003735 structural constituent of ribosome [PMID:18782943]
experiment: EXISTENCE:direct assay:GO:0022625 cytosolic large ribosomal subunit [PMID:18782943]
experiment: EXISTENCE:direct assay:GO:0030687 preribosome, large subunit precursor [PMID:23268442]
experiment: EXISTENCE:genetic interaction:GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:23268442]
note: Ribosomal 60S subunit protein L17B; required for processing of 27SB pre-rRNA and formation of stable 66S assembly intermediates; homologous to mammalian ribosomal protein L17 and bacterial L22; RPL17B has a paralog, RPL17A, that arose from the whole genome duplication
codon start: 1
product: ribosomal 60S subunit protein L17B
translation: MARYGATSTNPAKSASARGSYLRVSFKNTRETAQAINGWELTKAQKYLDQVLDHQRAIPFRRFNSSIGRTAQGKEFGVTKARWPAKSVKFVQGLLQNAAANAEAKGLDATKLYVSHIQVNQAPKQRRRTYRAHGRINKYESSPSHIELVVTEKEEAVAKAAEKKVVRLTSRQRGRIAAQKRISA
SIO_010081: YJL177W
subclass of: SO_0000673
so part of: YJL177W
location: join(90786..91094,91412..91657)
location: region:90786-91657:1
so has part: feature:90786-91094:1:exon
so has part: feature:91412-91657:1:exon

NP_012358.1
type: Protein
SIO_000068: ncbiprotein

S000003713
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:90786-91094:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:91412-91657:1:exon

YJL176C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: HAF2
alternative label: TYE2
gene: SWI3
locus tag: YJL176C
gene synonym: HAF2; TYE2
so part of: sequence
location: complement(<92053..>94530)
location: region:92053-94530:-1
so has part: feature:92053-94530:-1:exon
subclass of: SO_0000010

853264
type: Gene
SIO_000068: ncbigene

position:92053:-1
position: 92053
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:94530:-1
position: 94530
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:92053-94530:-1:exon

YJL176C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: HAF2
alternative label: TYE2
gene: SWI3
locus tag: YJL176C
gene synonym: HAF2; TYE2
product: Swi3p
transcript id: NM_001181609.1
SIO_010081: YJL176C
subclass of: SO_0000673
so part of: YJL176C
location: complement(<92053..>94530)
location: region:92053-94530:-1
so has part: feature:92053-94530:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:92053-94530:-1:exon

YJL176C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: HAF2
alternative label: TYE2
gene: SWI3
locus tag: YJL176C
gene synonym: HAF2; TYE2
experiment: EXISTENCE:direct assay:GO:0003677 DNA binding [PMID:16461455]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:1339306|PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0006338 chromatin remodeling [PMID:8016655]
experiment: EXISTENCE:direct assay:GO:0016514 SWI/SNF complex [PMID:18644858|PMID:8016655|PMID:8127913|PMID:8159677]
experiment: EXISTENCE:mutant phenotype:GO:0000436 carbon catabolite activation of transcription from RNA polymerase II promoter [PMID:8221926]
experiment: EXISTENCE:mutant phenotype:GO:0003677 DNA binding [PMID:16461455]
experiment: EXISTENCE:mutant phenotype:GO:0016514 SWI/SNF complex [PMID:8159677]
experiment: EXISTENCE:mutant phenotype:GO:0031496 positive regulation of mating type switching [PMID:6436497]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:1339306|PMID:3542227]
experiment: EXISTENCE:physical interaction:GO:0042393 histone binding [PMID:17496903]
note: Subunit of the SWI/SNF chromatin remodeling complex; SWI/SNF regulates transcription by remodeling chromosomes; contains SANT domain that is required for SWI/SNF assembly; is essential for displacement of histone H2A-H2B dimers during ATP-dependent remodeling; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2; relocates to the cytosol under hypoxic conditions
codon start: 1
product: Swi3p
translation: MENTLGEGSTVNASVDVDQHGNDNNSDSNANAAVAGVANTDTAGEESQQQDESLKDEATVPNTRDAESEAITVTAKQQPTMQANKLDSQETPSTEESRAQNVFGQDNEDSDNLFGETESSVSNNEANTPSIPTNPVDNENNKPAIKEDSTIQDSNGDVKNMEDVKIQKEEEPENNTVIEGVKEESQPDENTKEMDEVEEDDEDDDQPMISPDNSIFGDTKSESKQLGNTSSVANTPSEIPDAHKAEQEDIIEKTESVDKKVDSGEERNEQEREIMNDHSKSANPKKTTITRVEPETFEIPQAHEIVIPSYSKWFNLEKIHSIEVQSLPEFFTNRIPSKTPEVYMRYRNFMVNSYRLNPNEYFSVTTARRNVSGDAAALFRLHKFLTKWGLINYQVDSKLLPKNIEPPLTSQYSTRHDAPRGLFPFESYKPSVQLPDMAKLKKMMNTSDSESTLYKYLKESKRKYDEITHPPSTTDDENGDKNDNGGKMNNEVSTSTSMTGDANLLEEGETSRPLKKVKILEQIDENWSKEDLQKLLKGIQEFGADWYKVAKNVGNKSPEQCILRFLQLPIEDKFLYGDGNGKGDNDNGLGPLKYAPHLPFSKSENPVLSTIAFLVGLVNPKTVQSMTQRAIQSAESIKSQKEEISDQKPIEHIKEGSEIAISSLGYRSHIFATNEERQMNFLTNELIRLQMEKLDAKLNHLKKLEKFMELERKTLERQQENLLIQRLNFNQNSSKIVNVLSKCLNLISDSNINNSSVAEKEEIRSQIDHFKSMLSKPETLSIGKNPFNKPNIETGENHNGQSISNENDVKPISIEAPQFYRYWSA
SIO_010081: YJL176C
subclass of: SO_0000673
so part of: YJL176C
location: complement(92053..94530)
location: region:92053-94530:-1
so has part: feature:92053-94530:-1:exon

NP_012359.1
type: Protein
SIO_000068: ncbiprotein

S000003712
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:92053-94530:-1:exon

YJL174W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: KRE9
locus tag: YJL174W
so part of: sequence
location: <95092..>95922
location: region:95092-95922:1
so has part: feature:95092-95922:1:exon
subclass of: SO_0000010

853265
type: Gene
SIO_000068: ncbigene

position:95092:1
position: 95092
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:95922:1
position: 95922
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:95092-95922:1:exon

YJL174W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: KRE9
locus tag: YJL174W
product: Kre9p
transcript id: NM_001181607.1
SIO_010081: YJL174W
subclass of: SO_0000673
so part of: YJL174W
location: <95092..>95922
location: region:95092-95922:1
so has part: feature:95092-95922:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:95092-95922:1:exon

YJL174W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: KRE9
locus tag: YJL174W
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005576 extracellular region [PMID:8413233]
experiment: EXISTENCE:mutant phenotype:GO:0006077 (1->6)-beta-D-glucan metabolic process [PMID:8413233]
experiment: EXISTENCE:mutant phenotype:GO:0031505 fungal-type cell wall organization [PMID:8413233]
note: Glycoprotein involved in cell wall beta-glucan assembly; null mutation leads to severe growth defects, aberrant multibudded morphology, and mating defects
codon start: 1
product: Kre9p
translation: MRLQRNSIICALVFLVSFVLGDVNIVSPSSKATFSPSGGTVSVPVEWMDNGAYPSLSKISTFTFSLCTGPNNNIDCVAVLASKITPSELTQDDKVYSYTAEFASTLTGNGQYYIQVFAQVDGQGYTIHYTPRFQLTSMGGVTAYTYSATTEPTPQTSIQTTTTNNAQATTIDSRSFTVPYTKQTGTSRFAPMQMQPNTKVTATTWTRKFATSAVTYYSTFGSLPEQATTITPGWSYTISSGVNYATPASMPSDNGGWYKPSKRLSLSARKINMRKV
SIO_010081: YJL174W
subclass of: SO_0000673
so part of: YJL174W
location: 95092..95922
location: region:95092-95922:1
so has part: feature:95092-95922:1:exon

NP_012361.1
type: Protein
SIO_000068: ncbiprotein

S000003710
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:95092-95922:1:exon

YJL173C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RPA14
alternative label: RPA3
gene: RFA3
locus tag: YJL173C
gene synonym: RPA14; RPA3
so part of: sequence
location: complement(<96161..>96529)
location: region:96161-96529:-1
so has part: feature:96161-96529:-1:exon
subclass of: SO_0000010

853266
type: Gene
SIO_000068: ncbigene

position:96161:-1
position: 96161
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:96529:-1
position: 96529
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:96161-96529:-1:exon

YJL173C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RPA14
alternative label: RPA3
gene: RFA3
locus tag: YJL173C
gene synonym: RPA14; RPA3
product: Rfa3p
transcript id: NM_001181606.1
SIO_010081: YJL173C
subclass of: SO_0000673
so part of: YJL173C
location: complement(<96161..>96529)
location: region:96161-96529:-1
so has part: feature:96161-96529:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:96161-96529:-1:exon

YJL173C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RPA14
alternative label: RPA3
gene: RFA3
locus tag: YJL173C
gene synonym: RPA14; RPA3
experiment: EXISTENCE:direct assay:GO:0000794 condensed nuclear chromosome [PMID:9679065]
experiment: EXISTENCE:direct assay:GO:0003690 double-stranded DNA binding [PMID:7761422]
experiment: EXISTENCE:direct assay:GO:0005662 DNA replication factor A complex [PMID:2554144]
experiment: EXISTENCE:direct assay:GO:0006265 DNA topological change [PMID:22885009]
experiment: EXISTENCE:direct assay:GO:0006268 DNA unwinding involved in DNA replication [PMID:2554144]
experiment: EXISTENCE:direct assay:GO:0006289 nucleotide-excision repair [PMID:8910442]
experiment: EXISTENCE:direct assay:GO:0030491 heteroduplex formation [PMID:12226081]
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:7761422]
experiment: EXISTENCE:genetic interaction:GO:0000724 double-strand break repair via homologous recombination [PMID:9679065]
experiment: EXISTENCE:mutant phenotype:GO:0000781 chromosome, telomeric region [PMID:14702040]
experiment: EXISTENCE:mutant phenotype:GO:0006260 DNA replication [PMID:9093844]
experiment: EXISTENCE:mutant phenotype:GO:0006281 DNA repair [PMID:9093844]
experiment: EXISTENCE:mutant phenotype:GO:0010833 telomere maintenance via telomere lengthening [PMID:22354040]
experiment: EXISTENCE:physical interaction:GO:0000722 telomere maintenance via recombination [PMID:2554144]
experiment: EXISTENCE:physical interaction:GO:0006312 mitotic recombination [PMID:2554144]
experiment: EXISTENCE:physical interaction:GO:0007004 telomere maintenance via telomerase [PMID:2554144]
experiment: EXISTENCE:physical interaction:GO:0007131 reciprocal meiotic recombination [PMID:2554144]
experiment: EXISTENCE:physical interaction:GO:0016567 protein ubiquitination [PMID:18342608]
experiment: EXISTENCE:physical interaction:GO:0045184 establishment of protein localization [PMID:2554144]
note: Subunit of heterotrimeric Replication Protein A (RPA); RPA is a highly conserved single-stranded DNA binding protein complex involved in DNA replication, repair, recombination; RPA protects against inappropriate telomere recombination, and upon telomere uncapping, prevents cell proliferation by a checkpoint-independent pathway; with Sgs1p-Top2p-Rmi1p, stimulates DNA catenation/decatenation activity of Top3p; protein abundance increases in response to DNA replication stress
codon start: 1
product: Rfa3p
translation: MASETPRVDPTEISNVNAPVFRIIAQIKSQPTESQLILQSPTISSKNGSEVEMITLNNIRVSMNKTFEIDSWYEFVCRNNDDGELGFLILDAVLCKFKENEDLSLNGVVALQRLCKKYPEIY
SIO_010081: YJL173C
subclass of: SO_0000673
so part of: YJL173C
location: complement(96161..96529)
location: region:96161-96529:-1
so has part: feature:96161-96529:-1:exon

NP_012362.1
type: Protein
SIO_000068: ncbiprotein

S000003709
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:96161-96529:-1:exon

YJL172W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CPS1
locus tag: YJL172W
so part of: sequence
location: <97737..>99467
location: region:97737-99467:1
so has part: feature:97737-99467:1:exon
subclass of: SO_0000010

853267
type: Gene
SIO_000068: ncbigene

position:97737:1
position: 97737
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:99467:1
position: 99467
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:97737-99467:1:exon

YJL172W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CPS1
locus tag: YJL172W
product: Gly-Xaa carboxypeptidase
transcript id: NM_001181605.1
SIO_010081: YJL172W
subclass of: SO_0000673
so part of: YJL172W
location: <97737..>99467
location: region:97737-99467:1
so has part: feature:97737-99467:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:97737-99467:1:exon

YJL172W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CPS1
locus tag: YJL172W
EC number: 3.4.17.4
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0000328 fungal-type vacuole lumen [PMID:1569061]
experiment: EXISTENCE:mutant phenotype:GO:0004180 carboxypeptidase activity [PMID:2026161]
experiment: EXISTENCE:mutant phenotype:GO:0006807 nitrogen compound metabolic process [PMID:2026161]
experiment: EXISTENCE:mutant phenotype:GO:0051603 proteolysis involved in protein catabolic process [PMID:2026161]
note: Vacuolar carboxypeptidase S; targeted to vacuole via Vps10p-dependent endosomal vacuolar protein sorting pathway and via AP-3 pathway; expression induced under low-nitrogen conditions
codon start: 1
product: Gly-Xaa carboxypeptidase
translation: MIALPVEKAPRKSLWQRHRAFISGIVALIIIGTFFLTSGLHPAPPHEAKRPHHGKGPMHSPKCEKIEPLSPSFKHSVDTILHDPAFRNSSIEKLSNAVRIPTVVQDKNPNPADDPDFYKHFYELHDYFEKTFPNIHKHLKLEKVNELGLLYTWEGSDPDLKPLLLMAHQDVVPVNNETLSSWKFPPFSGHYDPETDFVWGRGSNDCKNLLIAEFEAIEQLLIDGFKPNRTIVMSLGFDEEASGTLGAASLASFLHERYGDDGIYSIIDEGEGIMEVDKDVFVATPINAEKGYVDFEVSILGHGGHSSVPPDHTTIGIASELITEFEANPFDYEFEFDNPIYGLLTCAAEHSKSLSKDVKKTILGAPFCPRRKDKLVEYISNQSHLRSLIRTTQAVDIINGGVKANALPETTRFLINHRINLHSSVAEVFERNIEYAKKIAEKYGYGLSKNGDDYIIPETELGHIDITLLRELEPAPLSPSSGPVWDILAGTIQDVFENGVLQNNEEFYVTTGLFSGNTDTKYYWNLSKNIYRFVGSIIDIDLLKTLHSVNEHVDVPGHLSAIAFVYEYIVNVNEYA
SIO_010081: YJL172W
subclass of: SO_0000673
so part of: YJL172W
location: 97737..99467
location: region:97737-99467:1
so has part: feature:97737-99467:1:exon

NP_012363.1
type: Protein
SIO_000068: ncbiprotein

S000003708
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:97737-99467:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1006; Autonomously Replicating Sequence
so part of: sequence
location: 99458..99678
location: region:99458-99678:1
so has part: feature:99458-99678:1:region

S000028443
type: SGD
SIO_000068: sgd

position:99458:1
position: 99458
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:99678:1
position: 99678
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:99458-99678:1:region

YJL171C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TOH1
locus tag: YJL171C
so part of: sequence
location: complement(<99704..>100894)
location: region:99704-100894:-1
so has part: feature:99704-100894:-1:exon
subclass of: SO_0000010

853268
type: Gene
SIO_000068: ncbigene

position:99704:-1
position: 99704
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:100894:-1
position: 100894
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:99704-100894:-1:exon

YJL171C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TOH1
locus tag: YJL171C
product: Toh1p
transcript id: NM_001181604.2
SIO_010081: YJL171C
subclass of: SO_0000673
so part of: YJL171C
location: complement(<99704..>100894)
location: region:99704-100894:-1
so has part: feature:99704-100894:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:99704-100894:-1:exon

YJL171C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TOH1
locus tag: YJL171C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:16622836]
experiment: EXISTENCE:direct assay:GO:0009277 fungal-type cell wall [PMID:10383953]
note: GPI-anchored cell wall hypothetical protein; induced in response to cell wall damaging agents and by mutations in genes involved in cell wall biogenesis; sequence similarity to YBR162C/TOS1, a covalently bound cell wall protein; protein abundance increases in response to DNA replication stress
codon start: 1
product: Toh1p
translation: MLQSIVLSVCMFMLHTVAASGPQSYQKLDFTNVGFTGSYVDVNKFKDITNNESCTCEVGDRVWFSGKNAPLADYLSVHFRGPLKLKQFAFYTSPGFTVNNSRSSSDWNRLAYYESSSKTADNVTFLNHGGEASPCLGNALSYASSNGTGSASEATVLADGTLISSDQEYIIYSNVSCPKSGYDKGCGVYRSGIPAYYGYGGTTKMFLFEFEMPTETEKNSSSIGYYDLPAIWLLNDHIARTSQYPTNANCSCWASGCGEYDIFEAMNGTEKNHLYSTFHTFQGIEDLGTGIQSYGYITRNTTGTMKGGVVFDSSGNVVSFISDATPFNGTVSADTVNDLLAAIPENETYSSQLMSISATAPSTTSKSNGVALTKMQNGVWYYILAIFTAFTQVVLI
SIO_010081: YJL171C
subclass of: SO_0000673
so part of: YJL171C
location: complement(99704..100894)
location: region:99704-100894:-1
so has part: feature:99704-100894:-1:exon

NP_012364.2
type: Protein
SIO_000068: ncbiprotein

S000003707
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:99704-100894:-1:exon

YJL170C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ASG7
locus tag: YJL170C
so part of: sequence
location: complement(<101150..>101779)
location: region:101150-101779:-1
so has part: feature:101150-101779:-1:exon
subclass of: SO_0000010

853269
type: Gene
SIO_000068: ncbigene

position:101150:-1
position: 101150
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:101779:-1
position: 101779
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:101150-101779:-1:exon

YJL170C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ASG7
locus tag: YJL170C
product: Asg7p
transcript id: NM_001181603.1
SIO_010081: YJL170C
subclass of: SO_0000673
so part of: YJL170C
location: complement(<101150..>101779)
location: region:101150-101779:-1
so has part: feature:101150-101779:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:101150-101779:-1:exon

YJL170C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ASG7
locus tag: YJL170C
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:11073983]
experiment: EXISTENCE:expression pattern:GO:0000747 conjugation with cellular fusion [PMID:10568744]
note: Protein that regulates signaling from G protein beta subunit Ste4p; contributes to relocalization of Ste4p within the cell; specific to a-cells and induced by alpha-factor
codon start: 1
product: Asg7p
translation: MTTLASSIEHKTKHLAAPFENDENPWMKKYCCQCKSCKMSVPVQPWLPRFFVFGILCPVFWLVNLLAWWFLQYWQPHELEFHDLQEDEYPGFYEYEAITKRTVIPIKEEVLQEIRVMQNFSDSNSEEYYESKDGMPSSFLNVNTEQVEDENDTLKKYRYAFLKKVAHDVLESHDLLRKTFRDWNLRSLLGLLIDSILIIFVVLLCKKSR
SIO_010081: YJL170C
subclass of: SO_0000673
so part of: YJL170C
location: complement(101150..101779)
location: region:101150-101779:-1
so has part: feature:101150-101779:-1:exon

NP_012365.2
type: Protein
SIO_000068: ncbiprotein

S000003706
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:101150-101779:-1:exon

YJL168C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: EZL1
alternative label: KMT3
gene: SET2
locus tag: YJL168C
gene synonym: EZL1; KMT3
so part of: sequence
location: complement(<102227..>104428)
location: region:102227-104428:-1
so has part: feature:102227-104428:-1:exon
subclass of: SO_0000010

853271
type: Gene
SIO_000068: ncbigene

position:102227:-1
position: 102227
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:104428:-1
position: 104428
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:102227-104428:-1:exon

YJL168C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: EZL1
alternative label: KMT3
gene: SET2
locus tag: YJL168C
gene synonym: EZL1; KMT3
product: histone methyltransferase SET2
transcript id: NM_001181601.2
SIO_010081: YJL168C
subclass of: SO_0000673
so part of: YJL168C
location: complement(<102227..>104428)
location: region:102227-104428:-1
so has part: feature:102227-104428:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:102227-104428:-1:exon

YJL168C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: EZL1
alternative label: KMT3
gene: SET2
locus tag: YJL168C
gene synonym: EZL1; KMT3
EC number: 2.1.1.359
experiment: EXISTENCE:direct assay:GO:0003723 RNA binding [PMID:28483910]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0006354 DNA-templated transcription elongation [PMID:12736296]
experiment: EXISTENCE:direct assay:GO:0006355 regulation of DNA-templated transcription [PMID:11839797]
experiment: EXISTENCE:direct assay:GO:0046975 histone H3K36 methyltransferase activity [PMID:11839797]
experiment: EXISTENCE:mutant phenotype:GO:0006283 transcription-coupled nucleotide-excision repair [PMID:35263330]
experiment: EXISTENCE:mutant phenotype:GO:0006353 DNA-templated transcription termination [PMID:23109428]
experiment: EXISTENCE:mutant phenotype:GO:0006355 regulation of DNA-templated transcription [PMID:11839797]
experiment: EXISTENCE:mutant phenotype:GO:0030174 regulation of DNA-templated DNA replication initiation [PMID:19417103]
experiment: EXISTENCE:mutant phenotype:GO:0030437 ascospore formation [PMID:17150765]
experiment: EXISTENCE:mutant phenotype:GO:0045128 negative regulation of reciprocal meiotic recombination [PMID:18515193]
experiment: EXISTENCE:mutant phenotype:GO:0046975 histone H3K36 methyltransferase activity [PMID:11839797]
experiment: EXISTENCE:mutant phenotype:GO:0060195 negative regulation of antisense RNA transcription [PMID:21248844]
note: Histone methyltransferase with a role in transcriptional elongation; methylates H3 lysine 36 (H3K36), which suppresses incorporation of acetylated histones and signals for their deacetylation within transcribed genes; involved in transcription coupled-nucleotide excision repair; associates with C-terminal domain (CTD) of Rpo21p; H3K36me3 (trimethylation) requires Spt6p, proline 38 on H3, CTD of Rpo21p, Ctk1p, and C-terminal SRI domain of Ste2p; relocalizes to cytosol in response to hypoxia
codon start: 1
product: histone methyltransferase SET2
translation: MSKNQSVSASEDEKEILNNNAEGHKPQRLFDQEPDLTEEALTKFENLDDCIYANKRIGTFKNNDFMECDCYEEFSDGVNHACDEDSDCINRLTLIECVNDLCSSCGNDCQNQRFQKKQYAPIAIFKTKHKGYGVRAEQDIEANQFIYEYKGEVIEEMEFRDRLIDYDQRHFKHFYFMMLQNGEFIDATIKGSLARFCNHSCSPNAYVNKWVVKDKLRMGIFAQRKILKGEEITFDYNVDRYGAQAQKCYCEEPNCIGFLGGKTQTDAASLLPQNIADALGVTVSMEKKWLKLKKLSGEPIIKNENENINIEFLQSLEVQPIDSPVDVTKIMSVLLQQDNKIIASKLLKRLFTIDDDSLRHQAIKLHGYTCFSKMLKLFITEQPQVDGKGNETEEDDIKFIKGILDFLLELPKTTRNGIESSQIDNVVKTLPAKFPFLKPNCDELLEKWSKFETYKRITKKDINVAASKMIDLRRVRLPPGWEIIHENGRPLYYNAEQKTKLHYPPSGSSKVFSSRSNTQVNSPSSSGIPKTPGALDSKKHKLSDEEYERKKQKRLEYERIALERAKQEELESLKQKLKLENERKSVLEDIIAEANKQKELQKEEAKKLVEAKEAKRLKRKTVSQSQRLEHNWNKFFASFVPNLIKKNPQSKQFDHENIKQCAKDIVKILTTKELKKDSSRAPPDDLTKGKRHKVKEFINSYMDKIILKKKQKKALALSSASTRMSSPPPSTSS
SIO_010081: YJL168C
subclass of: SO_0000673
so part of: YJL168C
location: complement(102227..104428)
location: region:102227-104428:-1
so has part: feature:102227-104428:-1:exon

NP_012367.2
type: Protein
SIO_000068: ncbiprotein

S000003704
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:102227-104428:-1:exon

YJL167W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: BOT3
alternative label: FDS1
alternative label: FPP1
gene: ERG20
locus tag: YJL167W
gene synonym: BOT3; FDS1; FPP1
so part of: sequence
location: <105014..>106072
location: region:105014-106072:1
so has part: feature:105014-106072:1:exon
subclass of: SO_0000010

853272
type: Gene
SIO_000068: ncbigene

position:105014:1
position: 105014
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:106072:1
position: 106072
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:105014-106072:1:exon

YJL167W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: BOT3
alternative label: FDS1
alternative label: FPP1
gene: ERG20
locus tag: YJL167W
gene synonym: BOT3; FDS1; FPP1
product: bifunctional (2E,6E)-farnesyl diphosphate synthase/dimethylallyltranstransferase
transcript id: NM_001181600.1
SIO_010081: YJL167W
subclass of: SO_0000673
so part of: YJL167W
location: <105014..>106072
location: region:105014-106072:1
so has part: feature:105014-106072:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:105014-106072:1:exon

YJL167W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: BOT3
alternative label: FDS1
alternative label: FPP1
gene: ERG20
locus tag: YJL167W
gene synonym: BOT3; FDS1; FPP1
EC number: 2.5.1.1
EC number: 2.5.1.10
experiment: EXISTENCE:direct assay:GO:0004161 dimethylallyltranstransferase activity [PMID:2681213]
experiment: EXISTENCE:direct assay:GO:0004337 geranyltranstransferase activity [PMID:2681213]
experiment: EXISTENCE:direct assay:GO:0004452 isopentenyl-diphosphate delta-isomerase activity [PMID:7908830]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:19416104]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:19416104]
experiment: EXISTENCE:direct assay:GO:0006696 ergosterol biosynthetic process [PMID:7908830]
experiment: EXISTENCE:direct assay:GO:0008299 isoprenoid biosynthetic process [PMID:2681213]
experiment: EXISTENCE:direct assay:GO:0045337 farnesyl diphosphate biosynthetic process [PMID:2681213]
experiment: EXISTENCE:mutant phenotype:GO:0006696 ergosterol biosynthetic process [PMID:1779710]
note: Farnesyl pyrophosphate synthetase; has both dimethylallyltranstransferase and geranyltranstransferase activities; catalyzes the formation of C15 farnesyl pyrophosphate units for isoprenoid and sterol biosynthesis
codon start: 1
product: bifunctional (2E,6E)-farnesyl diphosphate synthase/dimethylallyltranstransferase
translation: MASEKEIRRERFLNVFPKLVEELNASLLAYGMPKEACDWYAHSLNYNTPGGKLNRGLSVVDTYAILSNKTVEQLGQEEYEKVAILGWCIELLQAYFLVADDMMDKSITRRGQPCWYKVPEVGEIAINDAFMLEAAIYKLLKSHFRNEKYYIDITELFHEVTFQTELGQLMDLITAPEDKVDLSKFSLKKHSFIVTFKTAYYSFYLPVALAMYVAGITDEKDLKQARDVLIPLGEYFQIQDDYLDCFGTPEQIGKIGTDIQDNKCSWVINKALELASAEQRKTLDENYGKKDSVAEAKCKKIFNDLKIEQLYHEYEESIAKDLKAKISQVDESRGFKADVLTAFLNKVYKRSK
SIO_010081: YJL167W
subclass of: SO_0000673
so part of: YJL167W
location: 105014..106072
location: region:105014-106072:1
so has part: feature:105014-106072:1:exon

NP_012368.1
type: Protein
SIO_000068: ncbiprotein

S000003703
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:105014-106072:1:exon

YJL166W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: COR5
gene: QCR8
locus tag: YJL166W
gene synonym: COR5
so part of: sequence
location: <106434..>106718
location: region:106434-106718:1
so has part: feature:106434-106718:1:exon
subclass of: SO_0000010

853273
type: Gene
SIO_000068: ncbigene

position:106434:1
position: 106434
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:106718:1
position: 106718
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:106434-106718:1:exon

YJL166W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: COR5
gene: QCR8
locus tag: YJL166W
gene synonym: COR5
product: ubiquinol--cytochrome-c reductase subunit 8
transcript id: NM_001181599.1
SIO_010081: YJL166W
subclass of: SO_0000673
so part of: YJL166W
location: <106434..>106718
location: region:106434-106718:1
so has part: feature:106434-106718:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:106434-106718:1:exon

YJL166W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: COR5
gene: QCR8
locus tag: YJL166W
gene synonym: COR5
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005750 mitochondrial respiratory chain complex III [PMID:10873857]
experiment: EXISTENCE:mutant phenotype:GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c [PMID:8394810]
experiment: EXISTENCE:mutant phenotype:GO:0008121 ubiquinol-cytochrome-c reductase activity [PMID:8786239]
experiment: EXISTENCE:mutant phenotype:GO:0009060 aerobic respiration [PMID:8394810]
note: Subunit 8 of ubiquinol cytochrome-c reductase (Complex III); Complex III is a component of the mitochondrial inner membrane electron transport chain; oriented facing the intermembrane space; expression is regulated by Abf1p and Cpf1p
codon start: 1
product: ubiquinol--cytochrome-c reductase subunit 8
translation: MGPPSGKTYMGWWGHMGGPKQKGITSYAVSPYAQKPLQGIFHNAVFNSFRRFKSQFLYVLIPAGIYWYWWKNGNEYNEFLYSKAGREELERVNV
SIO_010081: YJL166W
subclass of: SO_0000673
so part of: YJL166W
location: 106434..106718
location: region:106434-106718:1
so has part: feature:106434-106718:1:exon

NP_012369.1
type: Protein
SIO_000068: ncbiprotein

S000003702
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:106434-106718:1:exon

YJL165C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HAL5
locus tag: YJL165C
so part of: sequence
location: complement(<106894..>109461)
location: region:106894-109461:-1
so has part: feature:106894-109461:-1:exon
subclass of: SO_0000010

853274
type: Gene
SIO_000068: ncbigene

position:106894:-1
position: 106894
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:109461:-1
position: 109461
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:106894-109461:-1:exon

YJL165C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HAL5
locus tag: YJL165C
product: protein kinase HAL5
transcript id: NM_001181598.1
SIO_010081: YJL165C
subclass of: SO_0000673
so part of: YJL165C
location: complement(<106894..>109461)
location: region:106894-109461:-1
so has part: feature:106894-109461:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:106894-109461:-1:exon

YJL165C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: HAL5
locus tag: YJL165C
EC number: 2.7.11.1
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:16319894]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:32191698]
experiment: EXISTENCE:genetic interaction:GO:0008104 protein localization [PMID:21237705]
experiment: EXISTENCE:mutant phenotype:GO:0030003 cellular cation homeostasis [PMID:10207057]
experiment: EXISTENCE:mutant phenotype:GO:0045807 positive regulation of endocytosis [PMID:32191698]
note: Snf1p-related nutrient-responsive protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake, suggesting a role in regulation of Trk1p and/or Trk2p transporters; HAL5 has a paralog, KKQ8, that arose from the whole genome duplication
codon start: 1
product: protein kinase HAL5
translation: MGDEKLSRHTSLKRARSLSESIKGLFKPSGISGSNNAAAPSSRPGQDQAHSHQTARIITSNVSSPSISPVHSPVLQAAPKHHKLGVPNIAKLSLSPSREPSLNSENEMFSQESFISEKDEDEANLLEREDLQNKKEEKARAKHVRSKEAYVPHHRYTVGSDEVERQPRERLKNFPQNAGSSNPANSNANHVLDQENNFSIDAMLDYDEESKLRRRNSLGVRNHSNRTRSRKNSLSTPRSPPMKNGNGGMNSNATNNVGNGTGNRIYMRGRNHSDSISASSLPKFQEIECKCILDLGHFKVFENGYHEHSLRVLPIITNNKNVDSGDEKDADASVNSGDDGDNDSEANMHKQKSVFSLSGLFKSHKDGNQQQQQQQQQEENGEQINLEKAFSIIPSQRFIKSQTLKKSRTSNLKNGNNDELMKNDGKNIPQIVNPNAAVGVEELKLINALSEKIRKGLKSENTKGNNGEGRSNSNKQEDSDDTEGKAGTTNDDTSHKPCSQKYGKSIGVVGAGAYGVVKICARCKTAKDVLPYSTYSNGKKLFFAVKELKPKPGDQIDKFCTRLTSEFIIGHSLSHPHFEANAMIAGNVSRTTPPKHVFNAPNILKILDLMEYSNSFVEVMEFCASGDLYSLLTRNNISNESNNGSSRLIQTVKEGSGSPLHPLEADCFMKQLLNGVQYMHDHGIAHCDLKPENILFQPNGLLKICDFGTSSVFQTAWEKHVHFQSGAMGSEPYVAPEEFIRDAEYDPRLVDCWSCGIVYCTMVMGQYLWKIAIPEKDSLFKSFLSEIKDDGQFYLFEELRHVSSELNRLRKIALYRTFQVDPTKRITIEQLLQSSWMRKTKCCVVYRHLHTKVSK
SIO_010081: YJL165C
subclass of: SO_0000673
so part of: YJL165C
location: complement(106894..109461)
location: region:106894-109461:-1
so has part: feature:106894-109461:-1:exon

NP_012370.1
type: Protein
SIO_000068: ncbiprotein

S000003701
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:106894-109461:-1:exon

YJL164C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PKA1
alternative label: SRA3
gene: TPK1
locus tag: YJL164C
gene synonym: PKA1; SRA3
so part of: sequence
location: complement(<109966..>111159)
location: region:109966-111159:-1
so has part: feature:109966-111159:-1:exon
subclass of: SO_0000010

853275
type: Gene
SIO_000068: ncbigene

position:109966:-1
position: 109966
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:111159:-1
position: 111159
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:109966-111159:-1:exon

YJL164C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PKA1
alternative label: SRA3
gene: TPK1
locus tag: YJL164C
gene synonym: PKA1; SRA3
product: cAMP-dependent protein kinase catalytic subunit TPK1
transcript id: NM_001181597.2
SIO_010081: YJL164C
subclass of: SO_0000673
so part of: YJL164C
location: complement(<109966..>111159)
location: region:109966-111159:-1
so has part: feature:109966-111159:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:109966-111159:-1:exon

YJL164C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PKA1
alternative label: SRA3
gene: TPK1
locus tag: YJL164C
gene synonym: PKA1; SRA3
EC number: 2.7.11.11
experiment: EXISTENCE:direct assay:GO:0000785 chromatin [PMID:26403272]
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:16319894]
experiment: EXISTENCE:direct assay:GO:0004691 cAMP-dependent protein kinase activity [PMID:3036373|PMID:34244791]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:10625697]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:10625697]
experiment: EXISTENCE:direct assay:GO:0005952 cAMP-dependent protein kinase complex [PMID:12024012]
experiment: EXISTENCE:direct assay:GO:0018105 peptidyl-serine phosphorylation [PMID:34244791]
experiment: EXISTENCE:genetic interaction:GO:0004691 cAMP-dependent protein kinase activity [PMID:3036373]
experiment: EXISTENCE:genetic interaction:GO:0005952 cAMP-dependent protein kinase complex [PMID:3036373]
experiment: EXISTENCE:genetic interaction:GO:0006303 double-strand break repair via nonhomologous end joining [PMID:34244791|PMID:33008596]
experiment: EXISTENCE:genetic interaction:GO:0007265 Ras protein signal transduction [PMID:3036373]
experiment: EXISTENCE:genetic interaction:GO:0010607 negative regulation of cytoplasmic mRNA processing body assembly [PMID:21925385]
experiment: EXISTENCE:genetic interaction:GO:0010737 protein kinase A signaling [PMID:20133652]
experiment: EXISTENCE:mutant phenotype:GO:0004691 cAMP-dependent protein kinase activity [PMID:3036373]
experiment: EXISTENCE:mutant phenotype:GO:0006303 double-strand break repair via nonhomologous end joining [PMID:34244791|PMID:33008596]
experiment: EXISTENCE:mutant phenotype:GO:0006606 protein import into nucleus [PMID:34244791]
experiment: EXISTENCE:mutant phenotype:GO:0007265 Ras protein signal transduction [PMID:2823100]
experiment: EXISTENCE:mutant phenotype:GO:0016241 regulation of macroautophagy [PMID:15016820]
experiment: EXISTENCE:mutant phenotype:GO:0018105 peptidyl-serine phosphorylation [PMID:34244791]
experiment: EXISTENCE:physical interaction:GO:0005952 cAMP-dependent protein kinase complex [PMID:12024012]
note: cAMP-dependent protein kinase catalytic subunit; role in nutrient-stimulated growth via Ras-cAMP signaling; inhibited by regulatory subunit Bcy1p in cAMPs absence; phosphorylates and inhibits Whi3p to promote G1/S phase passage; phosphorylates Nej1p to regulate nonhomologous end joining (NHEJ); impairs mitochondrial import of pre-Tom40p via phosphorylation under non-respiratory conditions; partially redundant with Tpk2p and Tpk3p; human homolog PRKACB regulates NHEJ via NHEJ1 phosphorylation
codon start: 1
product: cAMP-dependent protein kinase catalytic subunit TPK1
translation: MSTEEQNGGGQKSLDDRQGEESQKGETSERETTATESGNESKSVEKEGGETQEKPKQPHVTYYNEEQYKQFIAQARVTSGKYSLQDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNEDVKDLLSRLITRDLSQRLGNLQNGTEDVKNHPWFKEVVWEKLLSRNIETPYEPPIQQGQGDTSQFDKYPEEDINYGVQGEDPYADLFRDF
SIO_010081: YJL164C
subclass of: SO_0000673
so part of: YJL164C
location: complement(109966..111159)
location: region:109966-111159:-1
so has part: feature:109966-111159:-1:exon

NP_012371.2
type: Protein
SIO_000068: ncbiprotein

S000003700
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:109966-111159:-1:exon

YJL163C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJL163C
so part of: sequence
location: complement(<111666..>113333)
location: region:111666-113333:-1
so has part: feature:111666-113333:-1:exon
subclass of: SO_0000010

853276
type: Gene
SIO_000068: ncbigene

position:111666:-1
position: 111666
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:113333:-1
position: 113333
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:111666-113333:-1:exon

YJL163C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJL163C
product: uncharacterized protein
transcript id: NM_001181596.1
SIO_010081: YJL163C
subclass of: SO_0000673
so part of: YJL163C
location: complement(<111666..>113333)
location: region:111666-113333:-1
so has part: feature:111666-113333:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:111666-113333:-1:exon

YJL163C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJL163C
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:26928762]
codon start: 1
product: uncharacterized protein
translation: MSNEDETTRLMSSDEMDYLLETAGINALEEIISQNDSTGINLDTNETAQDSSYDSIRRSPSILSVAKSVEGEHGRRKLLCLYGLVMIICIAESISMTATIPLVMDKVAEGISDENGHYDSVAVQTIVSSISSSTMMIAGAISIFMAGKWGELSDRIGRVRVFKYMSGIRVIGLLTHVFTLSSKMKYHKWAIVLTACIVPSFGGLFALVANGNSYVSDIVKTEHRMVTIGIMMSCIYATMGVGPMFGSFLVKWTHGNGFIPIYTSIAFVILALIICETIMVEPRHETQMAHSQSTYTKRREKLRSQSGSDDARNYQSVTYGKFQIMRLMDLLAPVKKLWLKPDSAGSLVPRHTVILLIVLDILFVCGTTSCMPALILFSTYEYKWHAVELGYFISILGIGRGVVLLVVSPTLLYTLKRIYQHLNHSIDKIDIFCIQFSMIVITLSLFVMIRFGEKTPTSMIIFALLQALSAFCSPTLQSGIIKYTSKKHTGEMFGAMALVRSCVMLVIPPILLKLYGSTVSVNPSLFMYIPFSTSIVAILLTFFLRIYKNPPLDGP
SIO_010081: YJL163C
subclass of: SO_0000673
so part of: YJL163C
location: complement(111666..113333)
location: region:111666-113333:-1
so has part: feature:111666-113333:-1:exon

NP_012372.1
type: Protein
SIO_000068: ncbiprotein

S000003699
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:111666-113333:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1007; Autonomously Replicating Sequence
so part of: sequence
location: 113678..113749
location: region:113678-113749:1
so has part: feature:113678-113749:1:region

S000028444
type: SGD
SIO_000068: sgd

position:113678:1
position: 113678
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:113749:1
position: 113749
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:113678-113749:1:region

YJL162C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: JJJ2
locus tag: YJL162C
so part of: sequence
location: complement(<113878..>115629)
location: region:113878-115629:-1
so has part: feature:113878-115629:-1:exon
subclass of: SO_0000010

853277
type: Gene
SIO_000068: ncbigene

position:113878:-1
position: 113878
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:115629:-1
position: 115629
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:113878-115629:-1:exon

YJL162C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: JJJ2
locus tag: YJL162C
product: Jjj2p
transcript id: NM_001181595.1
SIO_010081: YJL162C
subclass of: SO_0000673
so part of: YJL162C
location: complement(<113878..>115629)
location: region:113878-115629:-1
so has part: feature:113878-115629:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:113878-115629:-1:exon

YJL162C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: JJJ2
locus tag: YJL162C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
note: hypothetical protein; contains a J-domain, which is a region with homology to the E. coli DnaJ protein
codon start: 1
product: Jjj2p
translation: MSQVIEPQLDRTTYYSILGLTSNATSSEVHKSYLKLARLLHPDKTKSDKSEELFKAVVHAHSILTDEDQKLRYDRDLKIKGLHTYQPKKNCHIFKTKAKESQGASPTLGQSEAYHRQNKPYEQQPYGFGVGKKMTSSSKSKVPIFKSFNLKSYQRNHYYSSKKERKHGSPDIDSLFHETNGASKVRMTDAGKMDTNSQFQEIWEILGKNAYTHKSYSEDPNSCLGSALSDHEEEEEAGKQQQQQQQQQQQQQHYGMTSKSSSPDEEKKNNKEPKRESRVSPEENGEEETGHKQFKLPKTSTFSSGSHDSNLQSPFYNHEYRHYARSKFECKNQFRKSVSPIKEIPATTSANEGWNILRDIIEKLNISNVDDRNKDLLFRRDEIGDKNHSDSIDIENLSIKEPKGMKRRKKDDISLEELFQSLPREKDYFMMDAINDSLESINLFKKPKTTQSHEQGGTFAQAESNRAKFKPLLEQCGITPEILDLEIPEIPEFDAVADLETLKLNVQLFNNQCNKLKETIHQVSLQRLRADTQFSDMLTQKQSIMVWKTYLEFDKSLMDKLNILQERQMQVIKIFSERCDGKV
SIO_010081: YJL162C
subclass of: SO_0000673
so part of: YJL162C
location: complement(113878..115629)
location: region:113878-115629:-1
so has part: feature:113878-115629:-1:exon

NP_012373.2
type: Protein
SIO_000068: ncbiprotein

S000003698
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:113878-115629:-1:exon

YNCJ0002C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCJ0002C
so part of: sequence
location: complement(115939..116010)
location: region:115939-116010:-1
so has part: feature:115939-116010:-1:exon
subclass of: SO_0000663

853278
type: Gene
SIO_000068: ncbigene

position:115939:-1
position: 115939
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:116010:-1
position: 116010
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:115939-116010:-1:exon

YNCJ0002C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCJ0002C
product: tRNA-Glu
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Glutamate tRNA (tRNA-Glu), predicted by tRNAscan-SE analysis; thiolation of uridine at wobble position (34) requires Ncs6p; target of K. lactis zymocin
SIO_010081: YNCJ0002C
subclass of: SO_0000673
so part of: YNCJ0002C
location: complement(115939..116010)
location: region:115939-116010:-1
so has part: feature:115939-116010:-1:exon

S000006557
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:115939-116010:-1:exon

YJL161W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FMP33
locus tag: YJL161W
so part of: sequence
location: <117245..>117787
location: region:117245-117787:1
so has part: feature:117245-117787:1:exon
subclass of: SO_0000010

853279
type: Gene
SIO_000068: ncbigene

position:117245:1
position: 117245
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:117787:1
position: 117787
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:117245-117787:1:exon

YJL161W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FMP33
locus tag: YJL161W
product: Fmp33p
transcript id: NM_001181594.1
SIO_010081: YJL161W
subclass of: SO_0000673
so part of: YJL161W
location: <117245..>117787
location: region:117245-117787:1
so has part: feature:117245-117787:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:117245-117787:1:exon

YJL161W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FMP33
locus tag: YJL161W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095|PMID:14576278|PMID:16823961]
note: hypothetical protein; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
codon start: 1
product: Fmp33p
translation: MLYTRLLRHNSQFTKFSGTSPNLGSKPLFSKGNLYTSLLVTTLYGTGLACLYLESNSLNKSKEQEDPHAIAEDDIVNIVHDAPNRIFKPALDTYQEKELDLQKSDLHKVLHSLTYSDVSQFSIVWGFLIQLSSLIGNSTLGKKSILYKGSVVSVLGFPPLIYMALKLRMKQLEKAGVRFE
SIO_010081: YJL161W
subclass of: SO_0000673
so part of: YJL161W
location: 117245..117787
location: region:117245-117787:1
so has part: feature:117245-117787:1:exon

NP_012374.1
type: Protein
SIO_000068: ncbiprotein

S000003697
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:117245-117787:1:exon

YJL160C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PIR5
locus tag: YJL160C
so part of: sequence
location: complement(<117962..>118825)
location: region:117962-118825:-1
so has part: feature:117962-118825:-1:exon
subclass of: SO_0000010

853280
type: Gene
SIO_000068: ncbigene

position:117962:-1
position: 117962
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:118825:-1
position: 118825
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:117962-118825:-1:exon

YJL160C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PIR5
locus tag: YJL160C
product: beta-1,3-glucan linked protein
transcript id: NM_001181593.1
SIO_010081: YJL160C
subclass of: SO_0000673
so part of: YJL160C
location: complement(<117962..>118825)
location: region:117962-118825:-1
so has part: feature:117962-118825:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:117962-118825:-1:exon

YJL160C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PIR5
locus tag: YJL160C
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
note: hypothetical protein; member of the PIR (Proteins with Internal Repeats) family of cell wall proteins; SWAT-GFP fusion protein localizes to the endoplasmic reticulum and vacuole, and mCherry fusion localizes to the vacuole; non-essential gene that is required for sporulation; mRNA is weakly cell cycle regulated, peaking in mitosis; YJL160C has a paralog, PIR1, that arose from the whole genome duplication
codon start: 1
product: beta-1,3-glucan linked protein
translation: MHYKKAFLASLLSSIALTAYAPPEPWATLTPSSKMDGGTTEYRTSFGLAVIPFTVTESKVKRNVISQINDGQVQVTTQKLPHPVSQIGDGQIQVTTQKVPPVVSHIVSQIGDGQLQITTAKNVVTKSTIAVPSKTVTATATSTATAVSQIHDGQVQVTISSASSSSVLSKSKLEPTKKPNNEKVIKVQACKSSGTLAITLQGGVLIDSSGRIGSIVANRQFQFDGPPPQAGAIYAGGWSITKHGTLAIGDNDVFYQCLSGTFYNLYDQSIGGQCNPVHLQTVGLVDC
SIO_010081: YJL160C
subclass of: SO_0000673
so part of: YJL160C
location: complement(117962..118825)
location: region:117962-118825:-1
so has part: feature:117962-118825:-1:exon

NP_012375.2
type: Protein
SIO_000068: ncbiprotein

S000003696
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:117962-118825:-1:exon

YJL159W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CCW7
alternative label: ORE1
alternative label: PIR2
gene: HSP150
locus tag: YJL159W
gene synonym: CCW7; ORE1; PIR2
so part of: sequence
location: <120449..>121690
location: region:120449-121690:1
so has part: feature:120449-121690:1:exon
subclass of: SO_0000010

853281
type: Gene
SIO_000068: ncbigene

position:120449:1
position: 120449
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:121690:1
position: 121690
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:120449-121690:1:exon

YJL159W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CCW7
alternative label: ORE1
alternative label: PIR2
gene: HSP150
locus tag: YJL159W
gene synonym: CCW7; ORE1; PIR2
product: heat shock protein HSP150
transcript id: NM_001181592.1
SIO_010081: YJL159W
subclass of: SO_0000673
so part of: YJL159W
location: <120449..>121690
location: region:120449-121690:1
so has part: feature:120449-121690:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:120449-121690:1:exon

YJL159W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CCW7
alternative label: ORE1
alternative label: PIR2
gene: HSP150
locus tag: YJL159W
gene synonym: CCW7; ORE1; PIR2
experiment: EXISTENCE:direct assay:GO:0005199 structural constituent of cell wall [PMID:10209754]
experiment: EXISTENCE:direct assay:GO:0005576 extracellular region [PMID:19129178]
experiment: EXISTENCE:direct assay:GO:0005621 cellular bud scar [PMID:16278454]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0009277 fungal-type cell wall [PMID:10209754|PMID:15781460|PMID:9192695]
experiment: EXISTENCE:direct assay:GO:0016887 ATP hydrolysis activity [PMID:21446055]
experiment: EXISTENCE:mutant phenotype:GO:0016887 ATP hydrolysis activity [PMID:21446055]
experiment: EXISTENCE:mutant phenotype:GO:0031505 fungal-type cell wall organization [PMID:10407261]
note: O-mannosylated heat shock protein; secreted and covalently attached to the cell wall via beta-1,3-glucan and disulfide bridges; required for cell wall stability; induced by heat shock, oxidative stress, and nitrogen limitation; HSP150 has a paralog, PIR3, that arose from the whole genome duplication
codon start: 1
product: heat shock protein HSP150
translation: MQYKKTLVASALAATTLAAYAPSEPWSTLTPTATYSGGVTDYASTFGIAVQPISTTSSASSAATTASSKAKRAASQIGDGQVQAATTTASVSTKSTAAAVSQIGDGQIQATTKTTAAAVSQIGDGQIQATTKTTSAKTTAAAVSQISDGQIQATTTTLAPKSTAAAVSQIGDGQVQATTTTLAPKSTAAAVSQIGDGQVQATTKTTAAAVSQIGDGQVQATTKTTAAAVSQIGDGQVQATTKTTAAAVSQIGDGQVQATTKTTAAAVSQITDGQVQATTKTTQAASQVSDGQVQATTATSASAAATSTDPVDAVSCKTSGTLEMNLKGGILTDGKGRIGSIVANRQFQFDGPPPQAGAIYAAGWSITPDGNLAIGDNDVFYQCLSGTFYNLYDEHIGSQCTPVHLEAIDLIDC
SIO_010081: YJL159W
subclass of: SO_0000673
so part of: YJL159W
location: 120449..121690
location: region:120449-121690:1
so has part: feature:120449-121690:1:exon

NP_012376.3
type: Protein
SIO_000068: ncbiprotein

S000003695
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:120449-121690:1:exon

YJL158C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CCW11
alternative label: CCW5
alternative label: PIR4
alternative label: SCW8
gene: CIS3
locus tag: YJL158C
gene synonym: CCW11; CCW5; PIR4; SCW8
so part of: sequence
location: complement(<122265..>122948)
location: region:122265-122948:-1
so has part: feature:122265-122948:-1:exon
subclass of: SO_0000010

853282
type: Gene
SIO_000068: ncbigene

position:122265:-1
position: 122265
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:122948:-1
position: 122948
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:122265-122948:-1:exon

YJL158C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CCW11
alternative label: CCW5
alternative label: PIR4
alternative label: SCW8
gene: CIS3
locus tag: YJL158C
gene synonym: CCW11; CCW5; PIR4; SCW8
product: Cis3p
transcript id: NM_001181591.1
SIO_010081: YJL158C
subclass of: SO_0000673
so part of: YJL158C
location: complement(<122265..>122948)
location: region:122265-122948:-1
so has part: feature:122265-122948:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:122265-122948:-1:exon

YJL158C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CCW11
alternative label: CCW5
alternative label: PIR4
alternative label: SCW8
gene: CIS3
locus tag: YJL158C
gene synonym: CCW11; CCW5; PIR4; SCW8
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005576 extracellular region [PMID:12702350|PMID:19129178]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005934 cellular bud tip [PMID:10438739]
experiment: EXISTENCE:direct assay:GO:0009277 fungal-type cell wall [PMID:10438739|PMID:15781460]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0031505 fungal-type cell wall organization [PMID:10407261]
note: Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family
codon start: 1
product: Cis3p
translation: MQFKNVALAASVAALSATASAEGYTPGEPWSTLTPTGSISCGAAEYTTTFGIAVQAITSSKAKRDVISQIGDGQVQATSAATAQATDSQAQATTTATPTSSEKISSSASKTSTNATSSSCATPSLKDSSCKNSGTLELTLKDGVLTDAKGRIGSIVANRQFQFDGPPPQAGAIYAAGWSITEDGYLALGDSDVFYQCLSGNFYNLYDQNVAEQCSAIHLEAVSLVDC
SIO_010081: YJL158C
subclass of: SO_0000673
so part of: YJL158C
location: complement(122265..122948)
location: region:122265-122948:-1
so has part: feature:122265-122948:-1:exon

NP_012377.1
type: Protein
SIO_000068: ncbiprotein

S000003694
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:122265-122948:-1:exon

YJL157C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FAR1
locus tag: YJL157C
so part of: sequence
location: complement(<123836..>126328)
location: region:123836-126328:-1
so has part: feature:123836-126328:-1:exon
subclass of: SO_0000010

853283
type: Gene
SIO_000068: ncbigene

position:123836:-1
position: 123836
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:126328:-1
position: 126328
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:123836-126328:-1:exon

YJL157C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FAR1
locus tag: YJL157C
product: cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1
transcript id: NM_001181590.1
SIO_010081: YJL157C
subclass of: SO_0000673
so part of: YJL157C
location: complement(<123836..>126328)
location: region:123836-126328:-1
so has part: feature:123836-126328:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:123836-126328:-1:exon

YJL157C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FAR1
locus tag: YJL157C
experiment: EXISTENCE:direct assay:GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity [PMID:8066461]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:9822386|PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:9822386|PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:14988725]
experiment: EXISTENCE:direct assay:GO:0120171 Cdc24p-Far1p-Gbetagamma complex [PMID:10087263]
experiment: EXISTENCE:mutant phenotype:GO:0000751 mitotic cell cycle G1 arrest in response to pheromone [PMID:2147873]
experiment: EXISTENCE:mutant phenotype:GO:0043577 chemotropism [PMID:10087263|PMID:7490290]
experiment: EXISTENCE:mutant phenotype:GO:0051457 maintenance of protein location in nucleus [PMID:10655592]
experiment: EXISTENCE:physical interaction:GO:0120171 Cdc24p-Far1p-Gbetagamma complex [PMID:10087263]
note: CDK inhibitor and nuclear anchor; during the cell cycle Far1p sequesters the GEF Cdc24p in the nucleus; phosphorylation by Cdc28p-Cln results in SCFCdc4 complex-mediated ubiquitin-dependent degradation, releasing Cdc24p for export and activation of GTPase Cdc42p; in response to pheromone, phosphorylation of Far1p by MAPK Fus3p results in association with, and inhibition of Cdc28p-Cln, as well as Msn5p mediated nuclear export of Far1p-Cdc24p, targeting Cdc24p to polarity sites
codon start: 1
product: cyclin-dependent protein serine/threonine kinase inhibiting protein FAR1
translation: MKTPTRVSFEKKIHTPPSGDRDAERSPPKKFLRGLSGKVFRKTPEFKKQQMPTFGYIEESQFTPNLGLMMSKRGNIPKPLNLSKPISPPPSLKKTAGSVASGFSKTGQLSALQSPVNITSSNKYNIKATNLTTSLLRESISDSTTMCDTLSDINLTVMDEDYRIDGDSYYEEDSPTFMISLERNIKKCNSQFSPKRYIGEKCLICEESISSTFTGEKVVESTCSHTSHYNCYLMLFETLYFQGKFPECKICGEVSKPKDKDIVPEMVSKLLTGAGAHDDGPSSNMQQQWIDLKTARSFTGEFPQFTPQEQLIRTADISCDGFRTPRLSNSNQFEAVSYLDSPFLNSPFVNKMATTDPFDLSDDEKLDCDDEIDESAAEVWFSKTGGEHVMVSVKFQEMRTSDDLGVLQDVNHVDHEELEEREKEWKKKIDQYIETNVDKDSEFGSLILFDKLMYSDDGEQWVDNNLVILFSKFLVLFDFEEMKILGKIPRDQFYQVIKFNEDVLLCSLKSTNIPEIYLRFNENCEKWLLPKWKYCLENSSLETLPLSEIVSTVKELSHVNIIGALGAPPDVISAQSHDSRLPWKRLHSDTPLKLIVCLNLSHADGELYRKRVLKSVHQILDGLNTDDLLGIVVVGRDGSGVVGPFGTFIGMINKNWDGWTTFLDNLEVVNPNVFRDEKQQYKVTLQTCERLASTSAYVDTDDHIATGYAKQILVLNGSDVVDIEHDQKLKKAFDQLSYHWRYEISQRRMTPLNASIKQFLEELHTKRYLDVTLRLPQATFEQVYLGDMAAGEQKTRLIMDEHPHSSLIEIEYFDLVKQQRIHQTLEVPNL
SIO_010081: YJL157C
subclass of: SO_0000673
so part of: YJL157C
location: complement(123836..126328)
location: region:123836-126328:-1
so has part: feature:123836-126328:-1:exon

NP_012378.1
type: Protein
SIO_000068: ncbiprotein

S000003693
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:123836-126328:-1:exon

YJL156C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RAA3
gene: SSY5
locus tag: YJL156C
gene synonym: RAA3
so part of: sequence
location: complement(<126853..>128952)
location: region:126853-128952:-1
so has part: feature:126853-128952:-1:exon
subclass of: SO_0000010

853285
type: Gene
SIO_000068: ncbigene

position:126853:-1
position: 126853
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:128952:-1
position: 128952
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:126853-128952:-1:exon

YJL156C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RAA3
gene: SSY5
locus tag: YJL156C
gene synonym: RAA3
product: Ssy5p
transcript id: NM_001181589.1
SIO_010081: YJL156C
subclass of: SO_0000673
so part of: YJL156C
location: complement(<126853..>128952)
location: region:126853-128952:-1
so has part: feature:126853-128952:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:126853-128952:-1:exon

YJL156C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RAA3
gene: SSY5
locus tag: YJL156C
gene synonym: RAA3
experiment: EXISTENCE:direct assay:GO:0004252 serine-type endopeptidase activity [PMID:29661936|PMID:16778074]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:11154269]
experiment: EXISTENCE:direct assay:GO:0016485 protein processing [PMID:16778074]
experiment: EXISTENCE:genetic interaction:GO:0043200 response to amino acid [PMID:11154269]
experiment: EXISTENCE:mutant phenotype:GO:0004252 serine-type endopeptidase activity [PMID:16524914]
experiment: EXISTENCE:mutant phenotype:GO:0016485 protein processing [PMID:16524914]
experiment: EXISTENCE:mutant phenotype:GO:0016540 protein autoprocessing [PMID:29661936]
experiment: EXISTENCE:mutant phenotype:GO:0043200 response to amino acid [PMID:11154269]
note: Serine protease of SPS plasma membrane amino acid sensor system; contains an inhibitory domain that dissociates in response to extracellular amino acids, freeing a catalytic domain to activate transcription factor Stp1p; other members are Ssy1p and Ptr3p
codon start: 1
product: Ssy5p
translation: MVRFFGLNKKKNEEKENTDLPADNEQNAAETSSSNVSGNEERIDPNSHDTNPENANNDDASTTFGSSIQSSSIFSRGRMTYGTGASSSMATSEMRSHSSGHSGSKNSKNLQGFKDVGKPLRAVSFLSPVKEEESQDTQNTLDVSSSTSSTLATSENARENSFTSRRSITLEYIHKSLSELEENLVDIMDDIHQDVISISKAVIEAIEYFKEFLPTTRDRIPYRISLEKSSSLRKINKIVLHFLDNLLVSDAFSNSRSILLRRFYFFLKKLNLITDDDLISESGVLPCLSVFCIGSHCNLPSMDKLGMILDELTKMDSSIISDQEGAFIAPILRGITPKSSILTIMFGLPNLQHEHYEMIKVLYSLFPDVHMYCVKDYIKKAASAVGSIPSHTAATIDTIAPTKFQFSPPYAVSENPLELPISMSLSTETSAKITGTLGGYLFPQTGSDKKFSQFASCSFAITCAHVVLSEKQDYPNVMVPSNVLQTSYKKVLTKESDRYPDGSVEKTAFLEEVQRIDQNLNWQKSNKFGQVVWGERAIVDHRLSDFAIIKVNSSFKCQNTLGNGLKSFPDPTLRFQNLHVKRKIFKMKPGMKVFKIGASTGYTSGELNSTKLVYWADGKLQSSEFVVASPTPLFASAGDSGAWILTKLEDRLGLGLVGMLHSYDGEQRQFGLFTPIGDILERLHAVTKIQWDIDPQLDG
SIO_010081: YJL156C
subclass of: SO_0000673
so part of: YJL156C
location: complement(126853..128952)
location: region:126853-128952:-1
so has part: feature:126853-128952:-1:exon

NP_012379.2
type: Protein
SIO_000068: ncbiprotein

S000003692
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:126853-128952:-1:exon

YJL155C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FBP26
locus tag: YJL155C
so part of: sequence
location: complement(<129285..>130643)
location: region:129285-130643:-1
so has part: feature:129285-130643:-1:exon
subclass of: SO_0000010

853286
type: Gene
SIO_000068: ncbigene

position:129285:-1
position: 129285
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:130643:-1
position: 130643
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:129285-130643:-1:exon

YJL155C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FBP26
locus tag: YJL155C
product: fructose-2,6-bisphosphatase
transcript id: NM_001181588.1
SIO_010081: YJL155C
subclass of: SO_0000673
so part of: YJL155C
location: complement(<129285..>130643)
location: region:129285-130643:-1
so has part: feature:129285-130643:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:129285-130643:-1:exon

YJL155C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FBP26
locus tag: YJL155C
EC number: 3.1.3.46
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity [PMID:1322693]
experiment: EXISTENCE:mutant phenotype:GO:0006006 glucose metabolic process [PMID:1322693]
note: Fructose-2,6-bisphosphatase, required for glucose metabolism; protein abundance increases in response to DNA replication stress
codon start: 1
product: fructose-2,6-bisphosphatase
translation: MGYSTISNDNDIKVCVIMVGLPARGKSFISQKIIRYLSWLSIKAKCFNVGNYRRDVSGNVPMDAEFFNFENTDNFKLRELAAQNAIKDIVNFFTKEDGSVAVFDATNSTRKRRKWLKDICEKNNIQPMFLESWSNDHELIINNAKDIGSTSPDYENSEPHVAEADFLERIRQYERFYEPLDPQKDKDMTFIKLVNIIEEVVINKIRTYLESRIVFYVMNIRPKPKYIWLSRHGESIYNVEKKIGGDSSLSERGFQYAKKLEQLVKESAGEINLTVWTSTLKRTQQTANYLPYKKLQWKALDELDAGVCDGMTYEEIEKEYPEDFKARDNDKYEYRYRGGESYRDVVIRLEPVIMELERQENVLIITHQAVLRCIYAYFMNVPQEESPWMSIPLHTLIKLEPRAYGTKVTKIKANIPAVSTYKEKGTSQVGELSQSSTKLHQLLNDSPLEDKF
SIO_010081: YJL155C
subclass of: SO_0000673
so part of: YJL155C
location: complement(129285..130643)
location: region:129285-130643:-1
so has part: feature:129285-130643:-1:exon

NP_012380.1
type: Protein
SIO_000068: ncbiprotein

S000003691
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:129285-130643:-1:exon

YJL154C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ENV1
alternative label: GRD9
alternative label: VPT7
gene: VPS35
locus tag: YJL154C
gene synonym: ENV1; GRD9; VPT7
so part of: sequence
location: complement(<131101..>133935)
location: region:131101-133935:-1
so has part: feature:131101-133935:-1:exon
subclass of: SO_0000010

853287
type: Gene
SIO_000068: ncbigene

position:131101:-1
position: 131101
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:133935:-1
position: 133935
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:131101-133935:-1:exon

YJL154C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ENV1
alternative label: GRD9
alternative label: VPT7
gene: VPS35
locus tag: YJL154C
gene synonym: ENV1; GRD9; VPT7
product: retromer subunit VPS35
transcript id: NM_001181587.1
SIO_010081: YJL154C
subclass of: SO_0000673
so part of: YJL154C
location: complement(<131101..>133935)
location: region:131101-133935:-1
so has part: feature:131101-133935:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:131101-133935:-1:exon

YJL154C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ENV1
alternative label: GRD9
alternative label: VPT7
gene: VPS35
locus tag: YJL154C
gene synonym: ENV1; GRD9; VPT7
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:22593205]
experiment: EXISTENCE:mutant phenotype:GO:0030904 retromer complex [PMID:9700157]
experiment: EXISTENCE:mutant phenotype:GO:0045053 protein retention in Golgi apparatus [PMID:8649377]
experiment: EXISTENCE:mutant phenotype:GO:0140312 cargo adaptor activity [PMID:9700157]
experiment: EXISTENCE:physical interaction:GO:0005768 endosome [PMID:9700157]
experiment: EXISTENCE:physical interaction:GO:0030906 retromer, cargo-selective complex [PMID:9700157]
experiment: EXISTENCE:physical interaction:GO:0042147 retrograde transport, endosome to Golgi [PMID:9700157]
experiment: EXISTENCE:physical interaction:GO:0140312 cargo adaptor activity [PMID:9700157]
note: Endosomal subunit of membrane-associated retromer complex; required for retrograde transport; receptor that recognizes retrieval signals on cargo proteins, forms subcomplex with Vps26p and Vps29p that selects cargo proteins for retrieval; interacts with Ypt7p; overexpression of wild-type human VPS35 or Parkinson's-associated vps35-D686N or vps35-P299S variants complements Ni2+ resistance and Cd2+ sensitivity of yeast vps35 null mutant
codon start: 1
product: retromer subunit VPS35
translation: MAYADSPENAIAVIKQRTALMNRCLSQHKLMESLQHTSIMLTELRNPNLSPKKYYELYVIIFDSLTNLSTYLIENHPQNHHLADLYELVQYTGNVVPRLYLMITVGTSYLTFNEAPKKEILKDMIEMCRGVQNPIRGLFLRYYLSQRTKELLPEDDPSFNSQFIMNNFIEMNKLWVRLQHQGPLRERETRTRERKELQILVGSQLVRLSQIIDDNFQMYKQDILPTILEQVIQCRDLVSQEYLLDVICQVFADEFHLKTLDTLLQTTLHLNPDVSINKIVLTLVDRLNDYVTRQLEDDPNATSTNAYLDMDVFGTFWDYLTVLNHERPDLSLQQFIPLVESVIVLSLKWYPNNFDNLNKLFELVLQKTKDYGQKNISLESEHLFLVLLSFQNSKLQLTSSTTAPPNSPVTSKKHFIFQLISQCQAYKNILALQSISLQKKVVNEIIDILMDREVEEMADNDSESKLHPPGHSAYLVIEDKLQVQRLLSICEPLIISRSGPPANVASSDTNVDEVFFNRHDEEESWILDPIQEKLAHLIHWIMNTTSRKQTMKNKIQFSLEAQLEILLLIKSSFIKGGINVKYTFPAIITNFWKLMRKCRMIQEYLLKKRPDNKTLLSHYSNLLKQMFKFVSRCINDIFNSCNNSCTDLILKLNLQCAILADQLQLNEISYDFFSQAFTIFEESLSDSKTQLQALIYIAQSLQKTRSLYKEAYYDSLIVRCTLHGSKLLKKQDQCRAVYLCSHLWWATEISNIGEEEGITDNFYRDGKRVLECLQRSLRVADSIMDNEQSCELMVEILNRCLYYFIHGDESETHISIKYINGLIELIKTNLKSLKLEDNSASMITNSISDLHITGENNVKASSNADDGSVITDKESNVAIGSDGTYIQLNTLNGSSTLIRGVVATASGSKLLHQLKYIPIHHFRRTCEYIESQREVDDRFKVIYV
SIO_010081: YJL154C
subclass of: SO_0000673
so part of: YJL154C
location: complement(131101..133935)
location: region:131101-133935:-1
so has part: feature:131101-133935:-1:exon

NP_012381.1
type: Protein
SIO_000068: ncbiprotein

S000003690
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:131101-133935:-1:exon

YJL153C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: APR1
gene: INO1
locus tag: YJL153C
gene synonym: APR1
so part of: sequence
location: complement(<134332..>135933)
location: region:134332-135933:-1
so has part: feature:134332-135933:-1:exon
subclass of: SO_0000010

853288
type: Gene
SIO_000068: ncbigene

position:134332:-1
position: 134332
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:135933:-1
position: 135933
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:134332-135933:-1:exon

YJL153C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: APR1
gene: INO1
locus tag: YJL153C
gene synonym: APR1
product: inositol-3-phosphate synthase INO1
transcript id: NM_001181586.1
SIO_010081: YJL153C
subclass of: SO_0000673
so part of: YJL153C
location: complement(<134332..>135933)
location: region:134332-135933:-1
so has part: feature:134332-135933:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:134332-135933:-1:exon

YJL153C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: APR1
gene: INO1
locus tag: YJL153C
gene synonym: APR1
EC number: 5.5.1.4
experiment: EXISTENCE:direct assay:GO:0004512 inositol-3-phosphate synthase activity [PMID:7016881]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0006021 inositol biosynthetic process [PMID:7016881]
note: Inositol-3-phosphate synthase; involved in synthesis of inositol phosphates and inositol-containing phospholipids; transcription is coregulated with other phospholipid biosynthetic genes by Ino2p and Ino4p, which bind the UASINO DNA element
codon start: 1
product: inositol-3-phosphate synthase INO1
translation: MTEDNIAPITSVKVVTDKCTYKDNELLTKYSYENAVVTKTASGRFDVTPTVQDYVFKLDLKKPEKLGIMLIGLGGNNGSTLVASVLANKHNVEFQTKEGVKQPNYFGSMTQCSTLKLGIDAEGNDVYAPFNSLLPMVSPNDFVVSGWDINNADLYEAMQRSQVLEYDLQQRLKAKMSLVKPLPSIYYPDFIAANQDERANNCINLDEKGNVTTRGKWTHLQRIRRDIQNFKEENALDKVIVLWTANTERYVEVSPGVNDTMENLLQSIKNDHEEIAPSTIFAAASILEGVPYINGSPQNTFVPGLVQLAEHEGTFIAGDDLKSGQTKLKSVLAQFLVDAGIKPVSIASYNHLGNNDGYNLSAPKQFRSKEISKSSVIDDIIASNDILYNDKLGKKVDHCIVIKYMKPVGDSKVAMDEYYSELMLGGHNRISIHNVCEDSLLATPLIIDLLVMTEFCTRVSYKKVDPVKEDAGKFENFYPVLTFLSYWLKAPLTRPGFHPVNGLNKQRTALENFLRLLIGLPSQNELRFEERLL
SIO_010081: YJL153C
subclass of: SO_0000673
so part of: YJL153C
location: complement(134332..135933)
location: region:134332-135933:-1
so has part: feature:134332-135933:-1:exon

NP_012382.2
type: Protein
SIO_000068: ncbiprotein

S000003689
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:134332-135933:-1:exon

YJL151C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SNA3
locus tag: YJL151C
so part of: sequence
location: complement(<136372..>136773)
location: region:136372-136773:-1
so has part: feature:136372-136773:-1:exon
subclass of: SO_0000010

853290
type: Gene
SIO_000068: ncbigene

position:136372:-1
position: 136372
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:136773:-1
position: 136773
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:136372-136773:-1:exon

YJL151C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SNA3
locus tag: YJL151C
product: Sna3p
transcript id: NM_001181584.1
SIO_010081: YJL151C
subclass of: SO_0000673
so part of: YJL151C
location: complement(<136372..>136773)
location: region:136372-136773:-1
so has part: feature:136372-136773:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:136372-136773:-1:exon

YJL151C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SNA3
locus tag: YJL151C
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:22761830|PMID:23708375]
experiment: EXISTENCE:direct assay:GO:0000328 fungal-type vacuole lumen [PMID:12499386|PMID:17182850]
experiment: EXISTENCE:direct assay:GO:0031625 ubiquitin protein ligase binding [PMID:17182849|PMID:17332499]
experiment: EXISTENCE:mutant phenotype:GO:0030163 protein catabolic process [PMID:19944104]
experiment: EXISTENCE:mutant phenotype:GO:0031625 ubiquitin protein ligase binding [PMID:17182849|PMID:17332499]
experiment: EXISTENCE:mutant phenotype:GO:0032509 endosome transport via multivesicular body sorting pathway [PMID:22212814]
experiment: EXISTENCE:physical interaction:GO:0031625 ubiquitin protein ligase binding [PMID:17182849|PMID:17332499]
note: Protein involved in efficient MVB sorting of proteins to the vacuole; may function as an RSP5 adapter protein for MVB cargos; integral membrane protein localized to vacuolar intralumenal vesicles
codon start: 1
product: Sna3p
translation: MDRDHINDHDHRMSYSINKDDLLLMVLAVFIPPVAVWKRKGMFNRDTLLNLLLFLLLFFPAIIHACYVVYETSSERSYDLSRRHATAPAVDRDLEAHPAEESQAQPPAYDEDDEAGADVPLMDNKQQLSSGRT
SIO_010081: YJL151C
subclass of: SO_0000673
so part of: YJL151C
location: complement(136372..136773)
location: region:136372-136773:-1
so has part: feature:136372-136773:-1:exon

NP_012384.1
type: Protein
SIO_000068: ncbiprotein

S000003687
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:136372-136773:-1:exon

YJL149W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: DUH1
gene: DAS1
locus tag: YJL149W
gene synonym: DUH1
so part of: sequence
location: <137379..>139370
location: region:137379-139370:1
so has part: feature:137379-139370:1:exon
subclass of: SO_0000010

853292
type: Gene
SIO_000068: ncbigene

position:137379:1
position: 137379
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:139370:1
position: 139370
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:137379-139370:1:exon

YJL149W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: DUH1
gene: DAS1
locus tag: YJL149W
gene synonym: DUH1
product: SCF ubiquitin ligase complex subunit DAS1
transcript id: NM_001181582.1
SIO_010081: YJL149W
subclass of: SO_0000673
so part of: YJL149W
location: <137379..>139370
location: region:137379-139370:1
so has part: feature:137379-139370:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:137379-139370:1:exon

YJL149W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: DUH1
gene: DAS1
locus tag: YJL149W
gene synonym: DUH1
experiment: EXISTENCE:direct assay:GO:0019005 SCF ubiquitin ligase complex [PMID:11283612|PMID:14747994]
experiment: EXISTENCE:physical interaction:GO:0019005 SCF ubiquitin ligase complex [PMID:14747994]
note: Putative SCF ubiquitin ligase F-box protein; interacts physically with both Cdc53p and Skp1 and genetically with CDC34; similar to putative F-box protein YDR131C
codon start: 1
product: SCF ubiquitin ligase complex subunit DAS1
translation: MPFQDYFQKKKAAFINRNNKSNADASALRDINDININFAAKSKNYVFPLTKLPDELMQEVFSHLPQPDRLQLCLVNKRLNKIATKLLYRRIYLNDSNVVKSDFMHLAINWTLLNLPSSLKEEESRDIANCKLKKLIETLQNNIHITEVIQWIRINWDLDSTLQRSILSILCNQGKSLQRLENVTDPACNDIISNGHFSRSNVSSFDMAPPNSLPEMVVPENYIPNLTKYLSQRISSRLSHMTLFIDPLKLFNYLYPLDIKLQIIDLKLHWRREFYNNDYFVKKIRPGNPLTKLSEVFDKRTLKILTIISWNDTLLKRETEMLKDFKEFENLEDLSLISIKQDVHILVDLFSSLTNLKRLKMDFLEEYVPEPTNPHIFLSILLACSKLQFIDLRYDGLIPQIINIQENKFQLNQQCNCTNCQIVFSDILKGKIFMFPEDYYIHDLQDIAAKDIFKMMKYLSLLPYSKACDAYPSVRTQPMNLTNFVTKMNRNLLEYRNSKSQLVPKIVNNPHQHSTVTSTSTAHMSEPEMIIIDDDDDDDEINAAIPPSSDDTAATISTDLELPHESLTKRDIIMCYHALIHHFKSIYVTFLKSFPHLRFLMLNDIPTIVMEENNERIFEPVFYHYDYKSNLYGWSKESNKNLENDSNNNNNNSDTIARIATVM
SIO_010081: YJL149W
subclass of: SO_0000673
so part of: YJL149W
location: 137379..139370
location: region:137379-139370:1
so has part: feature:137379-139370:1:exon

NP_012386.1
type: Protein
SIO_000068: ncbiprotein

S000003685
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:137379-139370:1:exon

YNCJ0003C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SNR128
locus tag: YNCJ0003C
so part of: sequence
location: complement(139566..139691)
location: region:139566-139691:-1
so has part: feature:139566-139691:-1:exon
subclass of: SO_0000578

9164909
type: Gene
SIO_000068: ncbigene

position:139566:-1
position: 139566
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:139691:-1
position: 139691
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:139566-139691:-1:exon

YNCJ0003C
type: Non Coding RNA
subclass of: SO_0000655
RO_0002162: 559292
nc RNA class: snoRNA
gene: SNR128
locus tag: YNCJ0003C
product: SNR128
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:2850487]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22266655|PMID:31804585]
experiment: EXISTENCE:direct assay:GO:0031428 box C/D RNP complex [PMID:10094313]
experiment: EXISTENCE:genetic interaction:GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:7557394]
experiment: EXISTENCE:genetic interaction:GO:0019843 rRNA binding [PMID:7557394]
experiment: EXISTENCE:mutant phenotype:GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:2406561|PMID:7557394]
experiment: EXISTENCE:mutant phenotype:GO:0019843 rRNA binding [PMID:7557394]
experiment: EXISTENCE:physical interaction:GO:0031428 box C/D RNP complex [PMID:10733567|PMID:11081632]
note: C/D box small nucleolar RNA (snoRNA); referred to as U14; essential gene required for cleavage of 35S primary rRNA transcript to release the precursor to the 18S rRNA; guides 2'-O-methylation of small subunit (SSU) rRNA at position C414
transcript id: NR_132193.1
SIO_010081: YNCJ0003C
subclass of: SO_0000673
so part of: YNCJ0003C
location: complement(139566..139691)
location: region:139566-139691:-1
so has part: feature:139566-139691:-1:exon

S000006508
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:139566-139691:-1:exon

YNCJ0004C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SNR190
locus tag: YNCJ0004C
so part of: sequence
location: complement(139761..139950)
location: region:139761-139950:-1
so has part: feature:139761-139950:-1:exon
subclass of: SO_0000578

9164910
type: Gene
SIO_000068: ncbigene

position:139761:-1
position: 139761
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:139950:-1
position: 139950
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:139761-139950:-1:exon

YNCJ0004C
type: Non Coding RNA
subclass of: SO_0000655
RO_0002162: 559292
nc RNA class: snoRNA
gene: SNR190
locus tag: YNCJ0004C
product: SNR190
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:2850487]
experiment: EXISTENCE:direct assay:GO:0031428 box C/D RNP complex [PMID:10094313]
experiment: EXISTENCE:physical interaction:GO:0031428 box C/D RNP complex [PMID:10733567|PMID:11081632]
note: C/D box small nucleolar RNA (snoRNA); predicted to guide 2'-O-methylation of large subunit (LSU) rRNA at position G2395; not shown to be active
transcript id: NR_132194.1
SIO_010081: YNCJ0004C
subclass of: SO_0000673
so part of: YNCJ0004C
location: complement(139761..139950)
location: region:139761-139950:-1
so has part: feature:139761-139950:-1:exon

S000006509
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:139761-139950:-1:exon

YJL148W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CST21
gene: RPA34
locus tag: YJL148W
gene synonym: CST21
so part of: sequence
location: <140437..>141138
location: region:140437-141138:1
so has part: feature:140437-141138:1:exon
subclass of: SO_0000010

853293
type: Gene
SIO_000068: ncbigene

position:140437:1
position: 140437
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:141138:1
position: 141138
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:140437-141138:1:exon

YJL148W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CST21
gene: RPA34
locus tag: YJL148W
gene synonym: CST21
product: DNA-directed RNA polymerase I subunit RPA34
transcript id: NM_001181581.1
SIO_010081: YJL148W
subclass of: SO_0000673
so part of: YJL148W
location: <140437..>141138
location: region:140437-141138:1
so has part: feature:140437-141138:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:140437-141138:1:exon

YJL148W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CST21
gene: RPA34
locus tag: YJL148W
gene synonym: CST21
experiment: EXISTENCE:direct assay:GO:0001054 RNA polymerase I activity [PMID:9837969]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:12206772]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:12206772]
experiment: EXISTENCE:direct assay:GO:0005736 RNA polymerase I complex [PMID:11486042|PMID:9121426|PMID:9837969]
experiment: EXISTENCE:direct assay:GO:0006362 transcription elongation by RNA polymerase I [PMID:18160037]
experiment: EXISTENCE:genetic interaction:GO:0042790 nucleolar large rRNA transcription by RNA polymerase I [PMID:9121426]
experiment: EXISTENCE:mutant phenotype:GO:0005736 RNA polymerase I complex [PMID:9121426]
note: RNA polymerase I subunit A34.5; essential for nucleolar assembly and for high polymerase loading rate; nucleolar localization depends on Rpa49p
codon start: 1
product: DNA-directed RNA polymerase I subunit RPA34
translation: MSKLSKDYVSDSDSDDEVISNEFSIPDGFKKCKHLKNFPLNGDNKKKAKQQQVWLIKFPSNVDISKLKSLPVDFESSTTMTIDKHDYKIMDDTDIESSLTQDNLSNMTLLVPSESKESLKIASTAKDNAPLQFDKVFSVSETAKIPAIDYSKVRVPRKDVPKVEGLKLEHFATGYDAEDFHVAEEVKENKKEPKKRSHHDDEEESSEKKKKKKEKREKREKKDKKDKKKKHRD
SIO_010081: YJL148W
subclass of: SO_0000673
so part of: YJL148W
location: 140437..141138
location: region:140437-141138:1
so has part: feature:140437-141138:1:exon

NP_012387.1
type: Protein
SIO_000068: ncbiprotein

S000003684
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:140437-141138:1:exon

YJL147C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MRX5
gene: SMT1
locus tag: YJL147C
gene synonym: MRX5
so part of: sequence
location: complement(<141419..>142567)
location: region:141419-142567:-1
so has part: feature:141419-142567:-1:exon
subclass of: SO_0000010

853294
type: Gene
SIO_000068: ncbigene

position:141419:-1
position: 141419
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:142567:-1
position: 142567
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:141419-142567:-1:exon

YJL147C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MRX5
gene: SMT1
locus tag: YJL147C
gene synonym: MRX5
product: Smt1p
transcript id: NM_001181580.1
SIO_010081: YJL147C
subclass of: SO_0000673
so part of: YJL147C
location: complement(<141419..>142567)
location: region:141419-142567:-1
so has part: feature:141419-142567:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:141419-142567:-1:exon

YJL147C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MRX5
gene: SMT1
locus tag: YJL147C
gene synonym: MRX5
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095]
note: Translational repressor of the mitochondrial ATP6/8 mRNA; homozygous diploid deletion strain has a sporulation defect characterized by elevated dityrosine in the soluble fraction; expression induced by calcium shortage
codon start: 1
product: Smt1p
translation: MRRTFSQLATRLLKSKDDELKSTLKYLTKGPVKLLGPLFESSEVNEQGSLLNRSRTKENNLQNHHIENILRILNSNLPEVESKKQKVAVHYDVLFSHLNSIVTQATDNKSSSSKELQGSSSEDLYDRLLLLQYVGKLTNVRQITEILLSKKFNKFDKVWEHRALFDEYQRVVISILLYYRTHDVQIRKDYEPRWLSDYSDLPFPLRRLLWRCLTSNVSEDNIRQNIIHYIKLLGANWRNNDLILIYQSLYEKSHILPDLTVLNHNKDDGFSFTQNQILLVRILRAISKCVEEEPKLVKKWLIDIVKLSIQSKIMLESPKKPSTPIMDQYKFIRSLDISIRSIHRTCQDKLIFEDLQVNLGSVLKMINEEEHELKTHLPLNLI
SIO_010081: YJL147C
subclass of: SO_0000673
so part of: YJL147C
location: complement(141419..142567)
location: region:141419-142567:-1
so has part: feature:141419-142567:-1:exon

NP_012388.1
type: Protein
SIO_000068: ncbiprotein

S000003683
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:141419-142567:-1:exon

YJL146W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: IDS2
locus tag: YJL146W
so part of: sequence
location: <143292..>144701
location: region:143292-144701:1
so has part: feature:143292-144701:1:exon
subclass of: SO_0000010

853295
type: Gene
SIO_000068: ncbigene

position:143292:1
position: 143292
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:144701:1
position: 144701
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:143292-144701:1:exon

YJL146W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: IDS2
locus tag: YJL146W
product: Ids2p
transcript id: NM_001181579.1
SIO_010081: YJL146W
subclass of: SO_0000673
so part of: YJL146W
location: <143292..>144701
location: region:143292-144701:1
so has part: feature:143292-144701:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:143292-144701:1:exon

YJL146W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: IDS2
locus tag: YJL146W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0051087 chaperone binding [PMID:30516470]
experiment: EXISTENCE:mutant phenotype:GO:0051321 meiotic cell cycle [PMID:7565676]
experiment: EXISTENCE:mutant phenotype:GO:0061077 chaperone-mediated protein folding [PMID:30516470]
note: Protein involved in modulation of Ime2p activity during meiosis; appears to act indirectly to promote Ime2p-mediated late meiotic functions; found in growing cells and degraded during sporulation
codon start: 1
product: Ids2p
translation: MDNQQESISEDITGDLAAAVRKSWSESQDNPLLLNFNNSPIGTPTDRYSPEPATMMEGNAMNLSSLARGSTQQQQRLYGSSQTREKSDQQQQDYQLFKHHYSLGQETRESVSDILNDLTLGSPEPSERASPIRQPSVDVPPLTTRRSSIQDVQWIRHLLNPRSSFSGASSNEPTNSPGDFLNQSRAWITILHDSSAESLQAVIVLAESLKNVNSQYNLWVLHSSEVNAFQLAQVGIKTLIIDEYINLFMNFGTGSGFSASSQSTETKGELNFKWCKLFLFFSLIDRFELICYLSPTCLVLQNIDELLESTEVSDEIDNETCVLLSNKVNYINEDLVSVNQDQSSAENYDDDPQIIILKPNRAVAMCIKEYFTIYGNDFEGESKRSMFHQMNDLQIMKALFGDKWSYIDSVGYCAVPIASVPANRLNYKIIEFKILKPWERQNYIAAGQHRESIMNKWLDLWRDFLNQAN
SIO_010081: YJL146W
subclass of: SO_0000673
so part of: YJL146W
location: 143292..144701
location: region:143292-144701:1
so has part: feature:143292-144701:1:exon

NP_012389.1
type: Protein
SIO_000068: ncbiprotein

S000003682
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:143292-144701:1:exon

YJL145W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SFH5
locus tag: YJL145W
so part of: sequence
location: <145160..>146044
location: region:145160-146044:1
so has part: feature:145160-146044:1:exon
subclass of: SO_0000010

853296
type: Gene
SIO_000068: ncbigene

position:145160:1
position: 145160
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:146044:1
position: 146044
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:145160-146044:1:exon

YJL145W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SFH5
locus tag: YJL145W
product: Sfh5p
transcript id: NM_001181578.1
SIO_010081: YJL145W
subclass of: SO_0000673
so part of: YJL145W
location: <145160..>146044
location: region:145160-146044:1
so has part: feature:145160-146044:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:145160-146044:1:exon

YJL145W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SFH5
locus tag: YJL145W
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:19477927|PMID:12869188]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:19477927]
experiment: EXISTENCE:direct assay:GO:0008526 phosphatidylinositol transfer activity [PMID:10848624]
experiment: EXISTENCE:direct assay:GO:0015914 phospholipid transport [PMID:10848624]
experiment: EXISTENCE:direct assay:GO:0020037 heme binding [PMID:32780017]
experiment: EXISTENCE:direct assay:GO:0032541 cortical endoplasmic reticulum [PMID:16262726]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:12869188|PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0017157 regulation of exocytosis [PMID:19477927]
experiment: EXISTENCE:genetic interaction:GO:0043001 Golgi to plasma membrane protein transport [PMID:10848624]
experiment: EXISTENCE:genetic interaction:GO:0046488 phosphatidylinositol metabolic process [PMID:16262726]
experiment: EXISTENCE:genetic interaction:GO:2000114 regulation of establishment of cell polarity [PMID:19477927]
note: Unusual phosphatidylinositol transfer protein (PITP) that binds heme; similar to Sec14p; founding member of conserved class of fungal hemoproteins; exhibits PI- but not PC-transfer activity; localizes to peripheral endoplasmic reticulum, cytosol, and microsomes; partially relocalizes to plasma membrane upon DNA replication stress
codon start: 1
product: Sfh5p
translation: MKFDNDSEKQVFDKLKKAIPGIIKEKCAGYDELYGYKLNPEGLTQEEVDKYYDEKIADRLTYKLCKAYQFEYSTIVQNLIDILNWRREFNPLSCAYKEVHNTELQNVGILTFDANGDANKKAVTWNLYGQLVKKKELFQNVDKFVRYRIGLMEKGLSLLDFTSSDNNYMTQVHDYKGVSVWRMDSDIKNCSKTVIGIFQKYYPELLYAKYFVNVPTVFGWVYDLIKKFVDETTRKKFVVLTDGSKLGQYLKDCPYEGYGGKDKKNNLTKQNVTNVHPTEYGLYILQKQIIEDVE
SIO_010081: YJL145W
subclass of: SO_0000673
so part of: YJL145W
location: 145160..146044
location: region:145160-146044:1
so has part: feature:145160-146044:1:exon

NP_012390.1
type: Protein
SIO_000068: ncbiprotein

S000003681
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:145160-146044:1:exon

YJL144W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ROQ1
locus tag: YJL144W
so part of: sequence
location: <146359..>146673
location: region:146359-146673:1
so has part: feature:146359-146673:1:exon
subclass of: SO_0000010

853297
type: Gene
SIO_000068: ncbigene

position:146359:1
position: 146359
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:146673:1
position: 146673
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:146359-146673:1:exon

YJL144W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ROQ1
locus tag: YJL144W
product: Roq1p
transcript id: NM_001181577.1
SIO_010081: YJL144W
subclass of: SO_0000673
so part of: YJL144W
location: <146359..>146673
location: region:146359-146673:1
so has part: feature:146359-146673:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:146359-146673:1:exon

YJL144W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ROQ1
locus tag: YJL144W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0042631 cellular response to water deprivation [PMID:21420397]
experiment: EXISTENCE:mutant phenotype:GO:0055106 ubiquitin-protein transferase regulator activity [PMID:29861160]
experiment: EXISTENCE:mutant phenotype:GO:0120174 stress-induced homeostatically regulated protein degradation pathway [PMID:29861160]
experiment: EXISTENCE:physical interaction:GO:0055106 ubiquitin-protein transferase regulator activity [PMID:29861160]
note: Ub-ligase substrate-specificity factor; proteolytically-cleaved form acts as a pseudosubstrate, binding and altering the substrate specificity of Ubr1p towards misfolded and native ER membrane and cytosolic proteins, as part of the stress-induced homeostatically regulated protein degradation (SHRED) pathway; hydrophilin essential during desiccation-rehydration; induced by osmotic stress, starvation and during stationary phase; protein abundance increases in response to DNA replication stress
codon start: 1
product: Roq1p
translation: MLRRETSTIYRTHKKSNSSILRSQRDQTRVDSLVEESPMGDFGINNQPTQPGVIYYFVELTNLGIQENTSSNNNNNNNHGDDENGSRYGHGSSLGGDVHSRRCS
SIO_010081: YJL144W
subclass of: SO_0000673
so part of: YJL144W
location: 146359..146673
location: region:146359-146673:1
so has part: feature:146359-146673:1:exon

NP_012391.1
type: Protein
SIO_000068: ncbiprotein

S000003680
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:146359-146673:1:exon

YJL143W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MIM17
alternative label: MPI2
alternative label: SMS1
gene: TIM17
locus tag: YJL143W
gene synonym: MIM17; MPI2; SMS1
so part of: sequence
location: <147101..>147577
location: region:147101-147577:1
so has part: feature:147101-147577:1:exon
subclass of: SO_0000010

853298
type: Gene
SIO_000068: ncbigene

position:147101:1
position: 147101
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:147577:1
position: 147577
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:147101-147577:1:exon

YJL143W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MIM17
alternative label: MPI2
alternative label: SMS1
gene: TIM17
locus tag: YJL143W
gene synonym: MIM17; MPI2; SMS1
product: protein transporter TIM17
transcript id: NM_001181576.1
SIO_010081: YJL143W
subclass of: SO_0000673
so part of: YJL143W
location: <147101..>147577
location: region:147101-147577:1
so has part: feature:147101-147577:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:147101-147577:1:exon

YJL143W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MIM17
alternative label: MPI2
alternative label: SMS1
gene: TIM17
locus tag: YJL143W
gene synonym: MIM17; MPI2; SMS1
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005744 TIM23 mitochondrial import inner membrane translocase complex [PMID:15618217]
experiment: EXISTENCE:genetic interaction:GO:0000002 mitochondrial genome maintenance [PMID:18826960]
experiment: EXISTENCE:mutant phenotype:GO:0008320 protein transmembrane transporter activity [PMID:11344168|PMID:15618217]
experiment: EXISTENCE:mutant phenotype:GO:0030150 protein import into mitochondrial matrix [PMID:15618217|PMID:7600576|PMID:7919535|PMID:11344168]
experiment: EXISTENCE:physical interaction:GO:0005744 TIM23 mitochondrial import inner membrane translocase complex [PMID:7600576]
note: Essential component of the TIM23 complex; with Tim23p, contributes to the architecture and function of the import channel; may link the import motor to the core Translocase of the Inner Mitochondrial membrane (TIM23 complex)
codon start: 1
product: protein transporter TIM17
translation: MSADHSRDPCPIVILNDFGGAFAMGAIGGVVWHGIKGFRNSPLGERGSGAMSAIKARAPVLGGNFGVWGGLFSTFDCAVKAVRKREDPWNAIIAGFFTGGALAVRGGWRHTRNSSITCACLLGVIEGVGLMFQRYAAWQAKPMAPPLPEAPSSQPLQA
SIO_010081: YJL143W
subclass of: SO_0000673
so part of: YJL143W
location: 147101..147577
location: region:147101-147577:1
so has part: feature:147101-147577:1:exon

NP_012392.1
type: Protein
SIO_000068: ncbiprotein

S000003679
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:147101-147577:1:exon

YJL142C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: IRC9
locus tag: YJL142C
so part of: sequence
location: complement(<147819..>148211)
location: region:147819-148211:-1
so has part: feature:147819-148211:-1:exon
subclass of: SO_0000010

853299
type: Gene
SIO_000068: ncbigene

position:147819:-1
position: 147819
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:148211:-1
position: 148211
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:147819-148211:-1:exon

YJL142C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: IRC9
locus tag: YJL142C
product: Irc9p
transcript id: NM_001395034.1
SIO_010081: YJL142C
subclass of: SO_0000673
so part of: YJL142C
location: complement(<147819..>148211)
location: region:147819-148211:-1
so has part: feature:147819-148211:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:147819-148211:-1:exon

YJL142C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: IRC9
locus tag: YJL142C
experiment: EXISTENCE:mutant phenotype:GO:0006312 mitotic recombination [PMID:18085829]
experiment: EXISTENCE:mutant phenotype:GO:1990414 replication-born double-strand break repair via sister chromatid exchange [PMID:23357952]
note: hypothetical protein; partially overlaps verified gene YAK1/YJL141C but does not share all phenotypes; null mutant displays increased levels of spontaneous Rad52p foci, increased sporulation efficiency, and small defect in vacuolar fragmentation
codon start: 1
product: Irc9p
translation: MTMQKASKVNMEVRTTLVTMQATTMSIILALPLVVLIASTLVLSVKGRRIHLATSPIILLLLILFKKGQQARSINFTLSKNKSLFCLTFLNYPFHFITAWCHNDILNKYEFCLFLIFLIRIVITINKVTL
SIO_010081: YJL142C
subclass of: SO_0000673
so part of: YJL142C
location: complement(147819..148211)
location: region:147819-148211:-1
so has part: feature:147819-148211:-1:exon

NP_001381964.1
type: Protein
SIO_000068: ncbiprotein

S000003678
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:147819-148211:-1:exon

YJL141C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: YAK1
locus tag: YJL141C
so part of: sequence
location: complement(<147967..>150390)
location: region:147967-150390:-1
so has part: feature:147967-150390:-1:exon
subclass of: SO_0000010

853300
type: Gene
SIO_000068: ncbigene

position:147967:-1
position: 147967
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:150390:-1
position: 150390
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:147967-150390:-1:exon

YJL141C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: YAK1
locus tag: YJL141C
product: serine/threonine protein kinase YAK1
transcript id: NM_001181574.1
SIO_010081: YJL141C
subclass of: SO_0000673
so part of: YJL141C
location: complement(<147967..>150390)
location: region:147967-150390:-1
so has part: feature:147967-150390:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:147967-150390:-1:exon

YJL141C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: YAK1
locus tag: YJL141C
EC number: 2.7.12.1
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:2072907|PMID:24140345|PMID:16319894]
experiment: EXISTENCE:direct assay:GO:0004674 protein serine/threonine kinase activity [PMID:21255108]
experiment: EXISTENCE:direct assay:GO:0004713 protein tyrosine kinase activity [PMID:21255108]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:21255108|PMID:11358866]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:21255108|PMID:11358866]
experiment: EXISTENCE:genetic interaction:GO:0010737 protein kinase A signaling [PMID:8065298]
experiment: EXISTENCE:genetic interaction:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:24140345]
experiment: EXISTENCE:genetic interaction:GO:0061408 positive regulation of transcription from RNA polymerase II promoter in response to heat stress [PMID:24140345]
experiment: EXISTENCE:mutant phenotype:GO:0004674 protein serine/threonine kinase activity [PMID:21255108]
experiment: EXISTENCE:mutant phenotype:GO:0004713 protein tyrosine kinase activity [PMID:21255108]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:24140345]
experiment: EXISTENCE:mutant phenotype:GO:0061408 positive regulation of transcription from RNA polymerase II promoter in response to heat stress [PMID:24140345]
note: Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose
codon start: 1
product: serine/threonine protein kinase YAK1
translation: MNSSNNNDSSSSNSNMNNSLSPTLVTHSDASMGSGRASPDNSHMGRGIWNPSYVNQGSQRSPQQQHQNHHQQQQQQQQQQQQNSQFCFVNPWNEEKVTNSQQNLVYPPQYDDLNSNESLDAYRRRKSSLVVPPARAPAPNPFQYDSYPAYTSSNTSLAGNSSGQYPSGYQQQQQQVYQQGAIHPSQFGSRFVPSLYDRQDFQRRQSLAATNYSSNFSSLNSNTNQGTNSIPVMSPYRRLSAYPPSTSPPLQPPFKQLRRDEVQGQKLSIPQMQLCNSKNDLQPVLNATPKFRRASLNSKTISPLVSVTKSLITTYSLCSPEFTYQTSKNPKRVLTKPSEGKCNNGFDNINSDYILYVNDVLGVEQNRKYLVLDILGQGTFGQVVKCQNLLTKEILAVKVVKSRTEYLTQSITEAKILELLNQKIDPTNKHHFLRMYDSFVHKNHLCLVFELLSNNLYELLKQNKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPDKPELKIIDFGSSCEEARTVYTYIQSRFYRAPEIILGIPYSTSIDMWSLGCIVAELFLGIPIFPGASEYNQLTRIIDTLGYPPSWMIDMGKNSGKFMKKLAPEESSSSTQKHRMKTIEEFCREYNIVEKPSKQYFKWRKLPDIIRNYRYPKSIQNSQELIDQEMQNRECLIHFLGGVLNLNPLERWTPQQAMLHPFITKQEFTGEWFPPGSSLPGPSEKHDDAKGQQSEYGSANDSSNNAGHNYVYNPSSATGGADSVDIGAISKRKENTSGDISNNFAVTHSVQEGPTSAFNKLHIVEE
SIO_010081: YJL141C
subclass of: SO_0000673
so part of: YJL141C
location: complement(147967..150390)
location: region:147967-150390:-1
so has part: feature:147967-150390:-1:exon

NP_012394.1
type: Protein
SIO_000068: ncbiprotein

S000003677
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:147967-150390:-1:exon

YJL140W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CTF15
gene: RPB4
locus tag: YJL140W
gene synonym: CTF15
so part of: sequence
location: <150961..>151626
location: region:150961-151626:1
so has part: feature:150961-151626:1:exon
subclass of: SO_0000010

853301
type: Gene
SIO_000068: ncbigene

position:150961:1
position: 150961
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:151626:1
position: 151626
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:150961-151626:1:exon

YJL140W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CTF15
gene: RPB4
locus tag: YJL140W
gene synonym: CTF15
product: DNA-directed RNA polymerase II subunit RPB4
transcript id: NM_001181573.1
SIO_010081: YJL140W
subclass of: SO_0000673
so part of: YJL140W
location: <150961..>151626
location: region:150961-151626:1
so has part: feature:150961-151626:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:150961-151626:1:exon

YJL140W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CTF15
gene: RPB4
locus tag: YJL140W
gene synonym: CTF15
experiment: EXISTENCE:direct assay:GO:0000932 P-body [PMID:16357218]
experiment: EXISTENCE:direct assay:GO:0003697 single-stranded DNA binding [PMID:11087726]
experiment: EXISTENCE:direct assay:GO:0003727 single-stranded RNA binding [PMID:11087726]
experiment: EXISTENCE:direct assay:GO:0003968 RNA-dependent RNA polymerase activity [PMID:18004386]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:12857861]
experiment: EXISTENCE:direct assay:GO:0005665 RNA polymerase II, core complex [PMID:1331084|PMID:2183013|PMID:2186966]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:12857861]
experiment: EXISTENCE:direct assay:GO:0006367 transcription initiation at RNA polymerase II promoter [PMID:11087726]
experiment: EXISTENCE:mutant phenotype:GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [PMID:16357218]
experiment: EXISTENCE:mutant phenotype:GO:0006366 transcription by RNA polymerase II [PMID:11577101]
experiment: EXISTENCE:mutant phenotype:GO:0031990 mRNA export from nucleus in response to heat stress [PMID:12857861]
experiment: EXISTENCE:mutant phenotype:GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex [PMID:18195044]
experiment: EXISTENCE:mutant phenotype:GO:0045948 positive regulation of translational initiation [PMID:21074047]
experiment: EXISTENCE:physical interaction:GO:0031369 translation initiation factor binding [PMID:21074047]
note: RNA polymerase II subunit B32; forms dissociable heterodimer with Rpb7p; Rpb4/7 dissociates from RNAPII as Ser2 CTD phosphorylation increases; Rpb4/7 regulates cellular lifespan via mRNA decay process; involved in recruitment of 3'-end processing factors to transcribing RNAPII complex, export of mRNA to cytoplasm under stress conditions; also involved in translation initiation
codon start: 1
product: DNA-directed RNA polymerase II subunit RPB4
translation: MNVSTSTFQTRRRRLKKVEEEENAATLQLGQEFQLKQINHQGEEEELIALNLSEARLVIKEALVERRRAFKRSQKKHKKKHLKHENANDETTAVEDEDDDLDEDDVNADDDDFMHSETREKELESIDVLLEQTTGGNNKDLKNTMQYLTNFSRFRDQETVGAVIQLLKSTGLHPFEVAQLGSLACDTADEAKTLIPSLNNKISDDELERILKELSNLETLY
SIO_010081: YJL140W
subclass of: SO_0000673
so part of: YJL140W
location: 150961..151626
location: region:150961-151626:1
so has part: feature:150961-151626:1:exon

NP_012395.1
type: Protein
SIO_000068: ncbiprotein

S000003676
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:150961-151626:1:exon

YJL139C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: YUR1
locus tag: YJL139C
so part of: sequence
location: complement(<151713..>152999)
location: region:151713-152999:-1
so has part: feature:151713-152999:-1:exon
subclass of: SO_0000010

853302
type: Gene
SIO_000068: ncbigene

position:151713:-1
position: 151713
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:152999:-1
position: 152999
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:151713-152999:-1:exon

YJL139C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: YUR1
locus tag: YJL139C
product: mannosyltransferase YUR1
transcript id: NM_001181572.1
SIO_010081: YJL139C
subclass of: SO_0000673
so part of: YJL139C
location: complement(<151713..>152999)
location: region:151713-152999:-1
so has part: feature:151713-152999:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:151713-152999:-1:exon

YJL139C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: YUR1
locus tag: YJL139C
experiment: EXISTENCE:direct assay:GO:0000030 mannosyltransferase activity [PMID:8631921]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005794 Golgi apparatus [PMID:8631921]
experiment: EXISTENCE:mutant phenotype:GO:0000032 cell wall mannoprotein biosynthetic process [PMID:8631921]
experiment: EXISTENCE:mutant phenotype:GO:0006487 protein N-linked glycosylation [PMID:8631921]
note: Mannosyltransferase involved in protein N-glycosylation; member of the KTR1 family; located in the Golgi apparatus; YUR1 has a paralog, KTR2, that arose from the whole genome duplication
codon start: 1
product: mannosyltransferase YUR1
translation: MAKGGSLYIVGIFLPIWTFMIYIFGKELFLIRKYQKIDSTYTALSQRVKEQYDTSRRRNYFPKVKLSRNSYDDYTLNYTRQNDSDSFHLRENATILMLVRNSELEGALDSMRSLEDRFNNKYHYDWTFLNDVPFDQDFIEATTSMASGKTQYALIPPEDWNRPQWINDTLFEERLRVMEDEGVLYGGSKSYRNMCRFNSGFFFRQSILDNYDYYFRVEPNVKYYCDFPYDPFRVMRLKGKKYGFVISLYEYEETIPTLWDAVEEYLVASEETILRKEDSAYAFLTDSGLVGKHYPVVEANSDYNLCHFWSNFEIGDLNFFRSDEYKHFFETLDAKGGFYYERWGDAPVHSIGVSLLLRPDEIIHFDELGYFHSPFGTCPASYAVRLDQRCRCKSDDESVIDITPHSCLMRWWKNGSGKYFLKEEQDEI
SIO_010081: YJL139C
subclass of: SO_0000673
so part of: YJL139C
location: complement(151713..152999)
location: region:151713-152999:-1
so has part: feature:151713-152999:-1:exon

NP_012396.1
type: Protein
SIO_000068: ncbiprotein

S000003675
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:151713-152999:-1:exon

YJL138C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TIF2
locus tag: YJL138C
so part of: sequence
location: complement(<153504..>154691)
location: region:153504-154691:-1
so has part: feature:153504-154691:-1:exon
subclass of: SO_0000010

853303
type: Gene
SIO_000068: ncbigene

position:153504:-1
position: 153504
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:154691:-1
position: 154691
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:153504-154691:-1:exon

YJL138C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TIF2
locus tag: YJL138C
product: translation initiation factor eIF4A
transcript id: NM_001181571.1
SIO_010081: YJL138C
subclass of: SO_0000673
so part of: YJL138C
location: complement(<153504..>154691)
location: region:153504-154691:-1
so has part: feature:153504-154691:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:153504-154691:-1:exon

YJL138C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TIF2
locus tag: YJL138C
EC number: 3.6.4.13
experiment: EXISTENCE:direct assay:GO:0003724 RNA helicase activity [PMID:1502180]
experiment: EXISTENCE:direct assay:GO:0003743 translation initiation factor activity [PMID:1502180]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:16622836]
experiment: EXISTENCE:direct assay:GO:0006413 translational initiation [PMID:1502180]
experiment: EXISTENCE:direct assay:GO:0008186 ATP-dependent activity, acting on RNA [PMID:24471916]
experiment: EXISTENCE:direct assay:GO:0010494 cytoplasmic stress granule [PMID:26777405]
experiment: EXISTENCE:direct assay:GO:1901195 positive regulation of formation of translation preinitiation complex [PMID:29192585|PMID:30281017]
experiment: EXISTENCE:mutant phenotype:GO:0003724 RNA helicase activity [PMID:1502180]
experiment: EXISTENCE:mutant phenotype:GO:0003743 translation initiation factor activity [PMID:1502180]
experiment: EXISTENCE:mutant phenotype:GO:0006413 translational initiation [PMID:1502180]
experiment: EXISTENCE:mutant phenotype:GO:0016281 eukaryotic translation initiation factor 4F complex [PMID:10409745|PMID:2648398]
note: Translation initiation factor eIF4A; DEAD-box RNA helicase that couples ATPase activity to mRNA binding and unwinding; ATP hydrolysis accelerates the recruitment of mRNA during 48S preinitiation complex (PIC) assembly; ATPase activity stimulated by either eIF4G1 or by the PIC in an eIF3g and eIFGi subunit-dependent manner, independent of eIF4E and eIF4G; subunit of the mRNA cap-binding protein complex (eIF4F) with eIF4E and eIF4G; protein abundance increases in response to DNA replication stress
codon start: 1
product: translation initiation factor eIF4A
translation: MSEGITDIEESQIQTNYDKVVYKFDDMELDENLLRGVFGYGFEEPSAIQQRAIMPIIEGHDVLAQAQSGTGKTGTFSIAALQRIDTSVKAPQALMLAPTRELALQIQKVVMALAFHMDIKVHACIGGTSFVEDAEGLRDAQIVVGTPGRVFDNIQRRRFRTDKIKMFILDEADEMLSSGFKEQIYQIFTLLPPTTQVVLLSATMPNDVLEVTTKFMRNPVRILVKKDELTLEGIKQFYVNVEEEEYKYECLTDLYDSISVTQAVIFCNTRRKVEELTTKLRNDKFTVSAIYSDLPQQERDTIMKEFRSGSSRILISTDLLARGIDVQQVSLVINYDLPANKENYIHRIGRGGRFGRKGVAINFVTNEDVGAMRELEKFYSTQIEELPSDIATLLN
SIO_010081: YJL138C
subclass of: SO_0000673
so part of: YJL138C
location: complement(153504..154691)
location: region:153504-154691:-1
so has part: feature:153504-154691:-1:exon

NP_012397.1
type: Protein
SIO_000068: ncbiprotein

S000003674
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:153504-154691:-1:exon

YJL137C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GLG2
locus tag: YJL137C
so part of: sequence
location: complement(<154985..>156127)
location: region:154985-156127:-1
so has part: feature:154985-156127:-1:exon
subclass of: SO_0000010

853304
type: Gene
SIO_000068: ncbigene

position:154985:-1
position: 154985
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:156127:-1
position: 156127
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:154985-156127:-1:exon

YJL137C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GLG2
locus tag: YJL137C
product: glycogenin glucosyltransferase GLG2
transcript id: NM_001181570.1
SIO_010081: YJL137C
subclass of: SO_0000673
so part of: YJL137C
location: complement(<154985..>156127)
location: region:154985-156127:-1
so has part: feature:154985-156127:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:154985-156127:-1:exon

YJL137C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GLG2
locus tag: YJL137C
EC number: 2.4.1.186
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:genetic interaction:GO:0005978 glycogen biosynthetic process [PMID:8524228]
experiment: EXISTENCE:genetic interaction:GO:0008466 glycogenin glucosyltransferase activity [PMID:8524228]
note: Glycogenin glucosyltransferase; self-glucosylating initiator of glycogen synthesis, also glucosylates n-dodecyl-beta-D-maltoside; similar to mammalian glycogenin; GLG2 has a paralog, GLG1, that arose from the whole genome duplication
codon start: 1
product: glycogenin glucosyltransferase GLG2
translation: MAKKVAICTLLYSRDYLPGALTLAYQLQKLLKHAVVEDEITLCLLIEKKLFGDEFKPQEIALIRSLFKEIIIIEPLKDQEKSIEKNKANLELLKRPELSHTLLKARLWELVQFDQVLFLDADTLPLNKEFFEILRLYPEQTRFQIAAVPDIGWPDMFNTGVLLLIPDLDMATSLQDFLIKTVSIDGADQGIFNQFFNPICNYSKEVLHKVSPLMEWIRLPFTYNVTMPNYGYQSSPAMNFFQQHIRLIHFIGTFKPWSRNTTDYDDHYYQLWRSTQRELYSECHLSNYFTHLQLGNIETETNFYHEPPCLQDLLNHGKRENQKHVDLDITSVDRNASQKSTAEKHDIEKPTSKPQSAFKFDWESTDYLDRVQRAFPKPDT
SIO_010081: YJL137C
subclass of: SO_0000673
so part of: YJL137C
location: complement(154985..156127)
location: region:154985-156127:-1
so has part: feature:154985-156127:-1:exon

NP_012398.1
type: Protein
SIO_000068: ncbiprotein

S000003673
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:154985-156127:-1:exon

YJL136W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJL136W-A
so part of: sequence
location: <156169..>156252
location: region:156169-156252:1
so has part: feature:156169-156252:1:exon
subclass of: SO_0000010

1466464
type: Gene
SIO_000068: ncbigene

position:156169:1
position: 156169
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:156252:1
position: 156252
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:156169-156252:1:exon

YJL136W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJL136W-A
product: uncharacterized protein
transcript id: NM_001184637.1
SIO_010081: YJL136W-A
subclass of: SO_0000673
so part of: YJL136W-A
location: <156169..>156252
location: region:156169-156252:1
so has part: feature:156169-156252:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:156169-156252:1:exon

YJL136W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJL136W-A
note: hypothetical protein; identified by SAGE
codon start: 1
product: uncharacterized protein
translation: MTRCISKKMLLEVDALSLIYSPHLYMS
SIO_010081: YJL136W-A
subclass of: SO_0000673
so part of: YJL136W-A
location: 156169..156252
location: region:156169-156252:1
so has part: feature:156169-156252:1:exon

NP_878101.1
type: Protein
SIO_000068: ncbiprotein

S000028806
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:156169-156252:1:exon

YJL136C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RPS21B
locus tag: YJL136C
so part of: sequence
location: complement(<156550..>157273)
location: region:156550-157273:-1
so has part: feature:156550-157273:-1:exon
subclass of: SO_0000010

853305
type: Gene
SIO_000068: ncbigene

position:156550:-1
position: 156550
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:157273:-1
position: 157273
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:156550-157273:-1:exon

YJL136C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RPS21B
locus tag: YJL136C
product: ribosomal 40S subunit protein S21B
transcript id: NM_001181569.1
SIO_010081: YJL136C
subclass of: SO_0000673
so part of: YJL136C
location: complement(join(<156550..156789,157250..>157273))
location: region:156550-157273:-1
so has part: feature:157250-157273:-1:exon
so has part: feature:156550-156789:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:157250-157273:-1:exon

position:157250:-1
position: 157250
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:156550-156789:-1:exon

position:156789:-1
position: 156789
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YJL136C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RPS21B
locus tag: YJL136C
experiment: EXISTENCE:curator inference:GO:0002181 cytoplasmic translation [PMID:3533916]
experiment: EXISTENCE:direct assay:GO:0003735 structural constituent of ribosome [PMID:3533916]
experiment: EXISTENCE:direct assay:GO:0022627 cytosolic small ribosomal subunit [PMID:3533916]
experiment: EXISTENCE:mutant phenotype:GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:14627813]
experiment: EXISTENCE:mutant phenotype:GO:0000461 endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:14627813]
note: Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S21, no bacterial homolog; RPS21B has a paralog, RPS21A, that arose from the whole genome duplication
codon start: 1
product: ribosomal 40S subunit protein S21B
translation: MENDKGQLVELYVPRKCSATNRIIKADDHASVQINVAKVDEEGRAIPGEYITYALSGYVRSRGESDDSLNRLAQNDGLLKNVWSYSR
SIO_010081: YJL136C
subclass of: SO_0000673
so part of: YJL136C
location: complement(join(156550..156789,157250..157273))
location: region:156550-157273:-1
so has part: feature:157250-157273:-1:exon
so has part: feature:156550-156789:-1:exon

NP_012399.1
type: Protein
SIO_000068: ncbiprotein

S000003672
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:157250-157273:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:156550-156789:-1:exon

YJL134W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LBP1
alternative label: YSR2
gene: LCB3
locus tag: YJL134W
gene synonym: LBP1; YSR2
so part of: sequence
location: <158188..>159417
location: region:158188-159417:1
so has part: feature:158188-159417:1:exon
subclass of: SO_0000010

853307
type: Gene
SIO_000068: ncbigene

position:158188:1
position: 158188
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:159417:1
position: 159417
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:158188-159417:1:exon

YJL134W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LBP1
alternative label: YSR2
gene: LCB3
locus tag: YJL134W
gene synonym: LBP1; YSR2
product: sphinganine kinase LCB3
transcript id: NM_001181567.1
SIO_010081: YJL134W
subclass of: SO_0000673
so part of: YJL134W
location: <158188..>159417
location: region:158188-159417:1
so has part: feature:158188-159417:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:158188-159417:1:exon

YJL134W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LBP1
alternative label: YSR2
gene: LCB3
locus tag: YJL134W
gene synonym: LBP1; YSR2
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:10477278|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0042392 sphingosine-1-phosphate phosphatase activity [PMID:9353337]
experiment: EXISTENCE:mutant phenotype:GO:0019722 calcium-mediated signaling [PMID:11278643]
note: Long-chain base-1-phosphate phosphatase; specific for dihydrosphingosine-1-phosphate, regulates ceramide and long-chain base phosphates levels, involved in incorporation of exogenous long chain bases in sphingolipids; LCB3 has a paralog, YSR3, that arose from the whole genome duplication
codon start: 1
product: sphinganine kinase LCB3
translation: MVDGLNTSNIRKRARTLSNPNDFQEPNYLLDPGNHPSDHFRTRMSKFRFNIREKLLVFTNNQSFTLSRWQKKYRSAFNDLYFTYTSLMGSHTFYVLCLPMPVWFGYFETTKDMVYILGYSIYLSGFFKDYWCLPRPRAPPLHRITLSEYTTKEYGAPSSHTANATGVSLLFLYNIWRMQESSVMVQLLLSCVVLFYYMTLVFGRIYCGMHGILDLVSGGLIGIVCFIVRMYFKYRFPGLRIEEHWWFPLFSVGWGLLLLFKHVKPVDECPCFQDSVAFMGVVSGIECCDWLGKVFGVTLVYNLEPNCGWRLTLARLLVGLPCVVIWKYVISKPMIYTLLIKVFHLKDDRNVAARKRLEATHKEGASKYECPLYIGEPKIDILGRFIIYAGVPFTVVMCSPVLFSLLNIA
SIO_010081: YJL134W
subclass of: SO_0000673
so part of: YJL134W
location: 158188..159417
location: region:158188-159417:1
so has part: feature:158188-159417:1:exon

NP_012401.1
type: Protein
SIO_000068: ncbiprotein

S000003670
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:158188-159417:1:exon

YJL133C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: DPI8
locus tag: YJL133C-A
so part of: sequence
location: complement(<159623..>159847)
location: region:159623-159847:-1
so has part: feature:159623-159847:-1:exon
subclass of: SO_0000010

1466465
type: Gene
SIO_000068: ncbigene

position:159623:-1
position: 159623
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:159847:-1
position: 159847
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:159623-159847:-1:exon

YJL133C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: DPI8
locus tag: YJL133C-A
product: Dpi8p
transcript id: NM_001184636.1
SIO_010081: YJL133C-A
subclass of: SO_0000673
so part of: YJL133C-A
location: complement(<159623..>159847)
location: region:159623-159847:-1
so has part: feature:159623-159847:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:159623-159847:-1:exon

YJL133C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: DPI8
locus tag: YJL133C-A
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
note: Putative mitochondrial hypothetical protein; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
codon start: 1
product: Dpi8p
translation: MIAQSTRLAAAVSSSAASAGVSRIAASAMASTIFKRSPGNSFNSFKEYRENAKTYGPLSASLATRRHLAHAPKL
SIO_010081: YJL133C-A
subclass of: SO_0000673
so part of: YJL133C-A
location: complement(159623..159847)
location: region:159623-159847:-1
so has part: feature:159623-159847:-1:exon

NP_878102.1
type: Protein
SIO_000068: ncbiprotein

S000028805
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:159623-159847:-1:exon

YJL133W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MRS3
locus tag: YJL133W
so part of: sequence
location: <160619..>161563
location: region:160619-161563:1
so has part: feature:160619-161563:1:exon
subclass of: SO_0000010

853308
type: Gene
SIO_000068: ncbigene

position:160619:1
position: 160619
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:161563:1
position: 161563
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:160619-161563:1:exon

YJL133W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MRS3
locus tag: YJL133W
product: Fe(2+) transporter
transcript id: NM_001181566.1
SIO_010081: YJL133W
subclass of: SO_0000673
so part of: YJL133W
location: <160619..>161563
location: region:160619-161563:1
so has part: feature:160619-161563:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:160619-161563:1:exon

YJL133W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MRS3
locus tag: YJL133W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:1703236]
experiment: EXISTENCE:direct assay:GO:0048250 iron import into the mitochondrion [PMID:12902335]
experiment: EXISTENCE:mutant phenotype:GO:0005381 iron ion transmembrane transporter activity [PMID:12902335]
note: Iron transporter, mediates Fe2+ transport across inner mito membrane; mitochondrial carrier family member; active under low-iron conditions; may transport other cations; MRS3 has a paralog, MRS4, that arose from the whole genome duplication
codon start: 1
product: Fe(2+) transporter
translation: MVENSSSNNSTRPIPAIPMDLPDYEALPTHAPLYHQLIAGAFAGIMEHSVMFPIDALKTRIQSANAKSLSAKNMLSQISHISTSEGTLALWKGVQSVILGAGPAHAVYFGTYEFCKKNLIDSSDTQTHHPFKTAISGACATTASDALMNPFDTIKQRIQLNTSASVWQTTKQIYQSEGLAAFYYSYPTTLVMNIPFAAFNFVIYESSTKFLNPSNEYNPLIHCLCGSISGSTCAAITTPLDCIKTVLQIRGSQTVSLEIMRKADTFSKAASAIYQVYGWKGFWRGWKPRIVANMPATAISWTAYECAKHFLMTY
SIO_010081: YJL133W
subclass of: SO_0000673
so part of: YJL133W
location: 160619..161563
location: region:160619-161563:1
so has part: feature:160619-161563:1:exon

NP_012402.1
type: Protein
SIO_000068: ncbiprotein

S000003669
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:160619-161563:1:exon

YJL132W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJL132W
so part of: sequence
location: <161914..>164166
location: region:161914-164166:1
so has part: feature:161914-164166:1:exon
subclass of: SO_0000010

853309
type: Gene
SIO_000068: ncbigene

position:161914:1
position: 161914
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:164166:1
position: 164166
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:161914-164166:1:exon

YJL132W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJL132W
product: uncharacterized protein
transcript id: NM_001181565.1
SIO_010081: YJL132W
subclass of: SO_0000673
so part of: YJL132W
location: <161914..>164166
location: region:161914-164166:1
so has part: feature:161914-164166:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:161914-164166:1:exon

YJL132W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJL132W
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0016020 membrane [PMID:11935221]
note: hypothetical protein; localizes to the membrane fraction; possible Zap1p-regulated target gene induced by zinc deficiency; YJL132W is a non-essential gene
codon start: 1
product: uncharacterized protein
translation: MSIISSWLLVSIICLTTSIVTKLQAAGVTTHLFYLTRGAPLSLKENYYPWLKAGSFFPDALYSCAPSNKDWSDFAEFTHWPNFLMIAVSYWQQKYGQNDRLRGTHGSLALKSFLIGVFTHQIVDVSWHSLVTDYRMHGLLRVLSETEFDGDIETAHTFLDVMGEFLTLNNVIRDSNNNENWDFLTRSDWKLPREEDLMEIIRNAGLSKEKLSYAELEFCVKRGMAAAISEGYLFRSQRNQLLTNIYSTSPRANDLILNHWLGGQSNLVAMLQRCVPFFETLFHDENTNEAQAEELRLCANLPPVSQKRINARPLVSSLKARKGNSHIVVSPMKSFSDFGTSLTMGKFREDNKDYLAVSAPLEDTVGAIYIVPWDILTVARKEDFSILQPITAMYGSKVGTYKASDVDYLLVSQPGTCTIDFYFKGVKILTIKDETTEEAHQLQFAVTGNFYDDKIPDLVVSSPSYGANETGIATFIPGSSIISYLTNSDKYQVVDISTFKGVINLDGYPMKIPFQHFGATIQISDTTDKQKLIYITCQSLGTVFVYSSNDLHDLSIPIYYITKNGVIPAKDSDHVEWHIIPSKEHGMFGAAIYSWNFEGMSFVAVSQPMFDTVFIYIEKSGQIEFFLKLVLKIKTKSDSIPDEFGSSLLFNDEEKKLYVSSPGSFDARGSIWKISMDELLKAGNDPKRKTLLINNLRHLMLINPDKSSKGVSNFGNSMILGPQNHLIVGIPQYGYGNFDHMQLTGRILVL
SIO_010081: YJL132W
subclass of: SO_0000673
so part of: YJL132W
location: 161914..164166
location: region:161914-164166:1
so has part: feature:161914-164166:1:exon

NP_012403.1
type: Protein
SIO_000068: ncbiprotein

S000003668
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:161914-164166:1:exon

YJL131C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MIF3
gene: AIM23
locus tag: YJL131C
gene synonym: MIF3
so part of: sequence
location: complement(<164278..>165348)
location: region:164278-165348:-1
so has part: feature:164278-165348:-1:exon
subclass of: SO_0000010

853310
type: Gene
SIO_000068: ncbigene

position:164278:-1
position: 164278
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:165348:-1
position: 165348
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:164278-165348:-1:exon

YJL131C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MIF3
gene: AIM23
locus tag: YJL131C
gene synonym: MIF3
product: Aim23p
transcript id: NM_001181564.1
SIO_010081: YJL131C
subclass of: SO_0000673
so part of: YJL131C
location: complement(<164278..>165348)
location: region:164278-165348:-1
so has part: feature:164278-165348:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:164278-165348:-1:exon

YJL131C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MIF3
gene: AIM23
locus tag: YJL131C
gene synonym: MIF3
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0097177 mitochondrial ribosome binding [PMID:30927524]
experiment: EXISTENCE:genetic interaction:GO:0070124 mitochondrial translational initiation [PMID:23954798]
note: Mitochondrial translation initiation factor 3 (IF3, mIF3); evolutionarily conserved; interacts with mitochondrial ribosomal small subunit; binds to E. coli ribosomes in vitro; null mutant displays severe respiratory growth defect and elevated frequency of mitochondrial genome loss
codon start: 1
product: Aim23p
translation: MLKVPLSDVLSQKMLFLKSFRYFHCTKYFSRDNASSTTDIFRNAMKRKRELANLKEQSHGNVARNAAFPKEYIKRPKQVPRNATNRKKILITWSTGTDRAKEAANSVVSEIFKKNHKGNIKVVDPTTHRIEASNIRYFAKGIDLDKVGLSIVNVEQIDNENQIPLVKIVESRVALKKYSDFLAKKKEKELMELGVLNKSYKNLVTDKKEDNLKHIKISWQIESDDLKRQKAHEIVSLLKKGNKVTLYLDDKNNINSNNWLENFEELDRSQKGEPPRLPESVFQKRAAVLETLKEIVSEYANDPVLLGNMNSKMIMKLIPKDVKPQNNDKRALKELRKKERQEKLQKRIQRKKMNEM
SIO_010081: YJL131C
subclass of: SO_0000673
so part of: YJL131C
location: complement(164278..165348)
location: region:164278-165348:-1
so has part: feature:164278-165348:-1:exon

NP_012404.1
type: Protein
SIO_000068: ncbiprotein

S000003667
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:164278-165348:-1:exon

YJL130C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: URA2
locus tag: YJL130C
so part of: sequence
location: complement(<165723..>172367)
location: region:165723-172367:-1
so has part: feature:165723-172367:-1:exon
subclass of: SO_0000010

853311
type: Gene
SIO_000068: ncbigene

position:165723:-1
position: 165723
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:172367:-1
position: 172367
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:165723-172367:-1:exon

YJL130C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: URA2
locus tag: YJL130C
product: bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase
transcript id: NM_001181563.2
SIO_010081: YJL130C
subclass of: SO_0000673
so part of: YJL130C
location: complement(<165723..>172367)
location: region:165723-172367:-1
so has part: feature:165723-172367:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:165723-172367:-1:exon

YJL130C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: URA2
locus tag: YJL130C
EC number: 2.1.3.2
EC number: 6.3.5.5
experiment: EXISTENCE:direct assay:GO:0004070 aspartate carbamoyltransferase activity [PMID:10446140]
experiment: EXISTENCE:direct assay:GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [PMID:5776390]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11015727]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process [PMID:181668]
experiment: EXISTENCE:direct assay:GO:0006541 glutamine metabolic process [PMID:5651325]
experiment: EXISTENCE:direct assay:GO:0016020 membrane [PMID:11921093]
experiment: EXISTENCE:direct assay:GO:0045984 negative regulation of pyrimidine nucleobase metabolic process [PMID:5651325]
experiment: EXISTENCE:mutant phenotype:GO:0004070 aspartate carbamoyltransferase activity [PMID:4550660]
experiment: EXISTENCE:mutant phenotype:GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process [PMID:4550660]
note: Bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase; catalyzes the first two enzymatic steps in the de novo biosynthesis of pyrimidines; both activities are subject to feedback inhibition by UTP
codon start: 1
product: bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase
translation: MATIAPTAPITPPMESTGDRLVTLELKDGTVLQGYSFGAEKSVAGELVFQTGMVGYPESVTDPSYEGQILVITYPLVGNYGVPDMHLRDELVEELPRYFESNRIHIAGLVISHYTDEYSHYLAKSSLGKWLQNEGIPAVYGVDTRSLTKHLRDAGSMLGRLSLEKSGSDRTISRSSSWRSAFDVPEWVDPNVQNLVSKVSINEPKLYVPPADNKHIELQTGPDGKVLRILAIDVGMKYNQIRCFIKRGVELKVVPWNYDFTKEDYDGLFISNGPGDPSVLDDLSQRLSNVLEAKKTPVFGICLGHQLIARAAGASTLKLKFGNRGHNIPCTSTISGRCYITSQNHGFAVDVDTLTSGWKPLFVNANDDSNEGIYHSELPYFSVQFHPESTPGPRDTEFLFDVFIQAVKEFKYTQVLKPIAFPGGLLEDNVKAHPRIEAKKVLVLGSGGLSIGQAGEFDYSGSQAIKALKEEGIYTILINPNIATIQTSKGLADKVYFVPVTAEFVRKVILHERPDAIYVTFGGQTALSVGIAMKDEFEALGVKVLGTPIDTIITTEDRELFSNAIDEINEKCAKSQAANSVDEALAAVKEIGFPVIVRAAYALGGLGSGFANNEKELVDLCNVAFSSSPQVLVEKSMKGWKEVEYEVVRDAFDNCITVCNMENFDPLGIHTGDSIVVAPSQTLSDEDYNMLRTTAVNVIRHLGVVGECNIQYALNPVSKDYCIIEVNARLSRSSALASKATGYPLAYTAAKLGLNIPLNEVKNSVTKSTCACFEPSLDYCVVKMPRWDLKKFTRVSTELSSSMKSVGEVMSIGRTFEEAIQKAIRSTEYANLGFNETDLDIDIDYELNNPTDMRVFAIANAFAKKGYSVDKVWEMTRIDKWFLNKLHDLVQFAEKISSFGTKEELPSLVLRQAKQLGFDDRQIARFLDSNEVAIRRLRKEYGITPFVKQIDTVAAEFPAYTNYLYMTYNADSHDLSFDDHGVMVLGSGVYRIGSSVEFDWCAVTAVRTLRANNIKTIMVNYNPETVSTDYDEADRLYFETINLERVLDIYEIENSSGVVVSMGGQTSNNIAMTLHRENVKILGTSPDMIDSAENRYKFSRMLDQIGVDQPAWKELTSMDEAESFAEKVGYPVLVRPSYVLSGAAMNTVYSKNDLESYLNQAVEVSRDYPVVITKYIENAKEIEMDAVARNGELVMHVVSEHVENAGVHSGDATLIVPPQDLAPETVDRIVVATAKIGKALKITGPYNIQFIAKDNEIKVIECNVRASRSFPFISKVVGVNLIELATKAIMGLPLTPYPVEKLPDDYVAVKVPQFSFPRLAGADPVLGVEMASTGEVATFGHSKYEAYLKSLLATGFKLPKKNILLSIGSYKEKQELLSSVQKLYNMGYKLFATSGTADFLSEHGIAVQYLEVLNKDDDDQKSEYSLTQHLANNEIDLYINLPSANRFRRPASYVSKGYKTRRLAVDYSVPLVTNVKCAKLLIEAISRNITLDVSERDAQTSHRTITLPGLINIATYVPNASHVIKGPAELKETTRLFLESGFTYCQLMPRSISGPVITDVASLKAANSVSQDSSYTDFSFTIAGTAHNAHSVTQSASKVTALFLPLRELKNKITAVAELLNQWPTEKQVIAEAKTADLASVLLLTSLQNRSIHITGVSNKEDLALIMTVKAKDPRVTCDVNIYSLFIAQDDYPEAVFLPTKEDQEFFWNNLDSIDAFSVGALPVALANVTGNKVDVGMGIKDSLPLLLAAVEEGKLTIDDIVLRLHDNPAKIFNIPTQDSVVEIDLDYSFRRNKRWSPFNKDMNGGIERVVYNGETLVLSGELVSPGAKGKCIVNPSPASITASAELQSTSAKRRFSITEEAIADNLDAAEDAIPEQPLEQKLMSSRPPRELVAPGAIQNLIRSNNPFRGRHILSIKQFKRSDFHVLFAVAQELRAAVAREGVLDLMKGHVITTIFFEPSTRTCSSFIAAMERLGGRIVNVNPLVSSVKKGETLQDTIRT…
SIO_010081: YJL130C
subclass of: SO_0000673
so part of: YJL130C
location: complement(165723..172367)
location: region:165723-172367:-1
so has part: feature:165723-172367:-1:exon

NP_012405.2
type: Protein
SIO_000068: ncbiprotein

S000003666
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:165723-172367:-1:exon

YJL129C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TRK1
locus tag: YJL129C
so part of: sequence
location: complement(<173599..>177306)
location: region:173599-177306:-1
so has part: feature:173599-177306:-1:exon
subclass of: SO_0000010

853312
type: Gene
SIO_000068: ncbigene

position:173599:-1
position: 173599
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:177306:-1
position: 177306
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:173599-177306:-1:exon

YJL129C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TRK1
locus tag: YJL129C
product: Trk1p
transcript id: NM_001181562.1
SIO_010081: YJL129C
subclass of: SO_0000673
so part of: YJL129C
location: complement(<173599..>177306)
location: region:173599-177306:-1
so has part: feature:173599-177306:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:173599-177306:-1:exon

YJL129C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TRK1
locus tag: YJL129C
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:16166647]
experiment: EXISTENCE:direct assay:GO:0015079 potassium ion transmembrane transporter activity [PMID:3043197]
experiment: EXISTENCE:direct assay:GO:0030007 cellular potassium ion homeostasis [PMID:3043197]
experiment: EXISTENCE:direct assay:GO:0045121 membrane raft [PMID:16166647]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0006874 cellular calcium ion homeostasis [PMID:33640956]
note: Component of the Trk1p-Trk2p potassium transport system; 180 kDa high affinity potassium transporter; phosphorylated in vivo and interacts physically with the phosphatase Ppz1p, suggesting Trk1p acitivy is regulated by phosphorylation; TRK1 has a paralog, TRK2, that arose from the whole genome duplication
codon start: 1
product: Trk1p
translation: MHFRRTMSRVPTLASLEIRYKKSFGHKFRDFIALCGHYFAPVKKYIFPSFIAVHYFYTISLTLITSILLYPIKNTRYIDTLFLAAGAVTQGGLNTVDINNLSLYQQIVLYIVCCISTPIAVHSCLAFVRLYWFERYFDGIRDSSRRNFKMRRTKTILERELTARTMTKNRTGTQRTSYPRKQAKTDDFQEKLFSGEMVNRDEQDSVHSDQNSHDISRDSSNNNTNHNGSSGSLDDFVKEDETDDNGEYQENNSYSTVGSSSNTVADESLNQKPKPSSLRFDEPHSKQRPARVPSEKFAKRRGSRDISPADMYRSIMMLQGKHEATAEDEGPPLVIGSPADGTRYKSNVNKLKKATGINGNKIKIRDKGNESNTDQNSVSSEANSTASVSDESSLHTNFGNKVPSLRTNTHRSNSGPIAITDNAETDKKHGPSIQFDITKPPRKISKRVSTFDDLNPKSSVLYRKKASKKYLMKHFPKARRIRQQIKRRLSTGSIEKNSSNNVSDRKPITDMDDDDDDDDNDGDNNEEYFADNESGDEDERVQQSEPHSDSELKSHQQQQEKHQLQQNLHRMYKTKSFDDNRSRAVPMERSRTIDMAEAKDLNELARTPDFQKMVYQNWKAHHRKKPNFRKRGWNNKIFEHGPYASDSDRNYPDNSNTGNSILHYAESILHHDGSHKNGSEEASSDSNENIYSTNGGSDHNGLNNYPTYNDDEEGYYGLHFDTDYDLDPRHDLSKGSGKTYLSWQPTIGRNSNFLGLTRAQKDELGGVEYRAIKLLCTILVVYYVGWHIVAFVMLVPWIILKKHYSEVVRDDGVSPTWWGFWTAMSAFNDLGLTLTPNSMMSFNKAVYPLIVMIWFIIIGNTGFPILLRCIIWIMFKISPDLSQMRESLGFLLDHPRRCFTLLFPKAATWWLLLTLAGLNITDWILFIILDFGSTVVKSLSKGYRVLVGLFQSVSTRTAGFSVVDLSQLHPSIQVSYMLMMYVSVLPLAISIRRTNVYEEQSLGLYGDMGGEPEDTDTEDDGNDEDDDEENESHEGQSSQRSSSNNNNNNNRKKKKKKKTENPNEISTKSFIGAHLRKQLSFDLWFLFLGLFIICICEGDKIKDVQEPNFNIFAILFEIVSAYGTVGLSLGYPDTNQSFSRQFTTLSKLVIIAMLIRGKNRGLPYSLDRAIILPSDRLEHIDHLEGMKLKRQARTNTEDPMTEHFKRSFTDVKHRWGALKRKTTHSRNPKRSSTTL
SIO_010081: YJL129C
subclass of: SO_0000673
so part of: YJL129C
location: complement(173599..177306)
location: region:173599-177306:-1
so has part: feature:173599-177306:-1:exon

NP_012406.1
type: Protein
SIO_000068: ncbiprotein

S000003665
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:173599-177306:-1:exon

YJL128C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: HOG4
alternative label: SFS4
alternative label: SSK4
gene: PBS2
locus tag: YJL128C
gene synonym: HOG4; SFS4; SSK4
so part of: sequence
location: complement(<178097..>180103)
location: region:178097-180103:-1
so has part: feature:178097-180103:-1:exon
subclass of: SO_0000010

853313
type: Gene
SIO_000068: ncbigene

position:178097:-1
position: 178097
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:180103:-1
position: 180103
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:178097-180103:-1:exon

YJL128C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: HOG4
alternative label: SFS4
alternative label: SSK4
gene: PBS2
locus tag: YJL128C
gene synonym: HOG4; SFS4; SSK4
product: mitogen-activated protein kinase kinase PBS2
transcript id: NM_001181561.2
SIO_010081: YJL128C
subclass of: SO_0000673
so part of: YJL128C
location: complement(<178097..>180103)
location: region:178097-180103:-1
so has part: feature:178097-180103:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:178097-180103:-1:exon

YJL128C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: HOG4
alternative label: SFS4
alternative label: SSK4
gene: PBS2
locus tag: YJL128C
gene synonym: HOG4; SFS4; SSK4
EC number: 2.7.12.2
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:16319894]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:9755161]
experiment: EXISTENCE:direct assay:GO:0005934 cellular bud tip [PMID:10980703]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:10980703]
experiment: EXISTENCE:direct assay:GO:0010494 cytoplasmic stress granule [PMID:26777405]
experiment: EXISTENCE:genetic interaction:GO:0000161 osmosensory signaling MAPK cascade [PMID:7624781]
experiment: EXISTENCE:genetic interaction:GO:0071474 cellular hyperosmotic response [PMID:7624781]
experiment: EXISTENCE:mutant phenotype:GO:0004708 MAP kinase kinase activity [PMID:7624781]
experiment: EXISTENCE:mutant phenotype:GO:0006606 protein import into nucleus [PMID:15707964]
experiment: EXISTENCE:mutant phenotype:GO:0006972 hyperosmotic response [PMID:7681220]
experiment: EXISTENCE:mutant phenotype:GO:0007015 actin filament organization [PMID:7941729]
experiment: EXISTENCE:mutant phenotype:GO:0007231 osmosensory signaling pathway [PMID:7624781]
experiment: EXISTENCE:physical interaction:GO:0005078 MAP-kinase scaffold activity [PMID:15200958|PMID:15200959|PMID:9180081]
experiment: EXISTENCE:physical interaction:GO:0005515 protein binding [PMID:14685261]
note: MAP kinase kinase of the HOG signaling pathway; activated under severe osmotic stress; mitophagy-specific regulator; plays a role in regulating Ty1 transposition
codon start: 1
product: mitogen-activated protein kinase kinase PBS2
translation: MEDKFANLSLHEKTGKSSIQLNEQTGSDNGSAVKRTSSTSSHYNNINADLHARVKAFQEQRALKRSASVGSNQSEQDKGSSQSPKHIQQIVNKPLPPLPVAGSSKVSQRMSSQVVQASSKSTLKNVLDNQETQNITDVNINIDTTKITATTIGVNTGLPATDITPSVSNTASATHKAQLLNPNRRAPRRPLSTQHPTRPNVAPHKAPAIINTPKQSLSARRGLKLPPGGMSLKMPTKTAQQPQQFAPSPSNKKHIETLSNSKVVEGKRSNPGSLINGVQSTSTSSSTEGPHDTVGTTPRTGNSNNSSNSGSSGGGGLFANFSKYVDIKSGSLNFAGKLSLSSKGIDFSNGSSSRITLDELEFLDELGHGNYGNVSKVLHKPTNVIMATKEVRLELDEAKFRQILMELEVLHKCNSPYIVDFYGAFFIEGAVYMCMEYMDGGSLDKIYDESSEIGGIDEPQLAFIANAVIHGLKELKEQHNIIHRDVKPTNILCSANQGTVKLCDFGVSGNLVASLAKTNIGCQSYMAPERIKSLNPDRATYTVQSDIWSLGLSILEMALGRYPYPPETYDNIFSQLSAIVDGPPPRLPSDKFSSDAQDFVSLCLQKIPERRPTYAALTEHPWLVKYRNQDVHMSEYITERLERRNKILRERGENGLSKNVPALHMGGL
SIO_010081: YJL128C
subclass of: SO_0000673
so part of: YJL128C
location: complement(178097..180103)
location: region:178097-180103:-1
so has part: feature:178097-180103:-1:exon

NP_012407.2
type: Protein
SIO_000068: ncbiprotein

S000003664
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:178097-180103:-1:exon

YJL127C-B
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YJL127C-A
gene: MCO6
locus tag: YJL127C-B
gene synonym: YJL127C-A
so part of: sequence
location: complement(<181551..>181709)
location: region:181551-181709:-1
so has part: feature:181551-181709:-1:exon
subclass of: SO_0000010

1466466
type: Gene
SIO_000068: ncbigene

position:181551:-1
position: 181551
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:181709:-1
position: 181709
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:181551-181709:-1:exon

YJL127C-B
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YJL127C-A
gene: MCO6
locus tag: YJL127C-B
gene synonym: YJL127C-A
product: Mco6p
transcript id: NM_001184532.1
SIO_010081: YJL127C-B
subclass of: SO_0000673
so part of: YJL127C-B
location: complement(<181551..>181709)
location: region:181551-181709:-1
so has part: feature:181551-181709:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:181551-181709:-1:exon

YJL127C-B
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YJL127C-A
gene: MCO6
locus tag: YJL127C-B
gene synonym: YJL127C-A
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:26928762]
note: Mitochondrial hypothetical protein; identified based on homology to the filamentous fungus, Ashbya gossypii; SWAT-GFP and seamless-GFP fusion proteins localize to the mitochondria
codon start: 1
product: Mco6p
translation: MIFFFNQIRSIFTALHTPTQQIQLSRRAFFQFLGYLGSCVVISLAAQSKYVQ
SIO_010081: YJL127C-B
subclass of: SO_0000673
so part of: YJL127C-B
location: complement(181551..181709)
location: region:181551-181709:-1
so has part: feature:181551-181709:-1:exon

NP_878103.1
type: Protein
SIO_000068: ncbiprotein

S000028522
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:181551-181709:-1:exon

YJL127C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CRE1
alternative label: SUD1
gene: SPT10
locus tag: YJL127C
gene synonym: CRE1; SUD1
so part of: sequence
location: complement(<182298..>184220)
location: region:182298-184220:-1
so has part: feature:182298-184220:-1:exon
subclass of: SO_0000010

853315
type: Gene
SIO_000068: ncbigene

position:182298:-1
position: 182298
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:184220:-1
position: 184220
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:182298-184220:-1:exon

YJL127C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CRE1
alternative label: SUD1
gene: SPT10
locus tag: YJL127C
gene synonym: CRE1; SUD1
product: Spt10p
transcript id: NM_001181560.1
SIO_010081: YJL127C
subclass of: SO_0000673
so part of: YJL127C
location: complement(<182298..>184220)
location: region:182298-184220:-1
so has part: feature:182298-184220:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:182298-184220:-1:exon

YJL127C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CRE1
alternative label: SUD1
gene: SPT10
locus tag: YJL127C
gene synonym: CRE1; SUD1
experiment: EXISTENCE:curator inference:GO:0032931 histone H3K56 acetyltransferase activity [PMID:15882620]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:16199888]
experiment: EXISTENCE:direct assay:GO:1990841 promoter-specific chromatin binding [PMID:15882620]
experiment: EXISTENCE:genetic interaction:GO:0030466 silent mating-type cassette heterochromatin formation [PMID:21057056]
experiment: EXISTENCE:mutant phenotype:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:26649943|PMID:17526727]
experiment: EXISTENCE:mutant phenotype:GO:0000183 rDNA heterochromatin formation [PMID:21057056]
experiment: EXISTENCE:mutant phenotype:GO:0006281 DNA repair [PMID:17078097]
experiment: EXISTENCE:mutant phenotype:GO:0010507 negative regulation of autophagy [PMID:26649943]
experiment: EXISTENCE:mutant phenotype:GO:0016573 histone acetylation [PMID:12192040]
experiment: EXISTENCE:mutant phenotype:GO:0031509 subtelomeric heterochromatin formation [PMID:21057056]
experiment: EXISTENCE:mutant phenotype:GO:0097043 histone H3-K56 acetylation [PMID:15882620]
note: Histone H3 acetylase with a role in transcriptional regulation; sequence-specific activator of histone genes, binds specifically and cooperatively to pairs of UAS elements in core histone promoters, functions at or near TATA box; involved in S phase-specific acetylation of H3K56 at histone promoters, which is required for recruitment of SWI/SNF nucleosome remodeling complex and subsequent transcription
codon start: 1
product: Spt10p
translation: MLNQHTSSVPDDEHLQMAHQNSSSEVRNEAAVPDQLLTPLQPYTILLKDGETIATMYPIPAYPDLLPLGLLNFLLDEFNMEVEKGDSFPYYETLSLEEFKNVWFHNDGHVCIMVLGEIPELDYSMDTEADTNDNFGTEIETTKHTTQYKKRKERRNLNLSMQWEKQCLGIFDLKPAYPGRSAHVVTGTFLVNAGIRGKGIGKTLMETFIEWSKKLGFTSSFFPLIYGTNVGIRRILEGLNFRRIGKLPEAGILKGFDVPVDSFMYGKEFTHITKSIDLLRDPQKSIEIGKYERLKHFLETGKYPLHCDRNEKARLRVLSKTHSVLNGKLMTKGKEIIYDTDQQIQIALEIHLMEHLGINKVTSKIGEKYHWRGIKSTVSEVISRCQKCKMRYKDGTGVIIEQKRAVKQAHMLPTQHIETINNPRKSKKHDNALLGQAINFPQNIISSTLNDVEGEPTPPDTNIVQPTFQNATNSPATTAEANEANKRSEFLSSIQSTPLLDDEQSMNSFNRFVEEENSRKRRKYLDVASNGIVPHLTNNESQDHANPVNRDERDMNHSVPDLDRNDHTIMNDAMLSLEDNVMAALEMVQKEQQQKINHRGEDVTGQQIDLNNSEGNENSVTKIVNNESNTFTEHNSNIYY
SIO_010081: YJL127C
subclass of: SO_0000673
so part of: YJL127C
location: complement(182298..184220)
location: region:182298-184220:-1
so has part: feature:182298-184220:-1:exon

NP_012408.1
type: Protein
SIO_000068: ncbiprotein

S000003663
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:182298-184220:-1:exon

YJL126W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: NIT2
locus tag: YJL126W
so part of: sequence
location: <184501..>185424
location: region:184501-185424:1
so has part: feature:184501-185424:1:exon
subclass of: SO_0000010

853316
type: Gene
SIO_000068: ncbigene

position:184501:1
position: 184501
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:185424:1
position: 185424
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:184501-185424:1:exon

YJL126W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: NIT2
locus tag: YJL126W
product: putative hydrolase
transcript id: NM_001181559.1
SIO_010081: YJL126W
subclass of: SO_0000673
so part of: YJL126W
location: <184501..>185424
location: region:184501-185424:1
so has part: feature:184501-185424:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:184501-185424:1:exon

YJL126W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: NIT2
locus tag: YJL126W
EC number: 3.5.1.128
experiment: EXISTENCE:direct assay:GO:0043605 amide catabolic process [PMID:28373563]
experiment: EXISTENCE:direct assay:GO:0110050 deaminated glutathione amidase activity [PMID:28373563]
note: Nit protein; one of two proteins in S. cerevisiae with similarity to the Nit domain of NitFhit from fly and worm and to the mouse and human Nit protein which interacts with the Fhit tumor suppressor; nitrilase superfamily member
codon start: 1
product: putative hydrolase
translation: MTSKLKRVAVAQLCSSADLTKNLKVVKELISEAIQKKADVVFLPEASDYLSQNPLHSRYLAQKSPKFIRQLQSSITDLVRDNSRNIDVSIGVHLPPSEQDLLEGNDRVRNVLLYIDHEGKILQEYQKLHLFDVDVPNGPILKESKSVQPGKAIPDIIESPLGKLGSAICYDIRFPEFSLKLRSMGAEILCFPSAFTIKTGEAHWELLGRARAVDTQCYVLMPGQVGMHDLSDPEWEKQSHMSALEKSSRRESWGHSMVIDPWGKIIAHADPSTVGPQLILADLDRELLQEIRNKMPLWNQRRDDLFH
SIO_010081: YJL126W
subclass of: SO_0000673
so part of: YJL126W
location: 184501..185424
location: region:184501-185424:1
so has part: feature:184501-185424:1:exon

NP_012409.1
type: Protein
SIO_000068: ncbiprotein

S000003662
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:184501-185424:1:exon

YJL125C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: TRM61
gene: GCD14
locus tag: YJL125C
gene synonym: TRM61
so part of: sequence
location: complement(<185528..>186679)
location: region:185528-186679:-1
so has part: feature:185528-186679:-1:exon
subclass of: SO_0000010

853317
type: Gene
SIO_000068: ncbigene

position:185528:-1
position: 185528
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:186679:-1
position: 186679
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:185528-186679:-1:exon

YJL125C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: TRM61
gene: GCD14
locus tag: YJL125C
gene synonym: TRM61
product: tRNA 1-methyladenosine methyltransferase subunit GCD14
transcript id: NM_001181558.1
SIO_010081: YJL125C
subclass of: SO_0000673
so part of: YJL125C
location: complement(<185528..>186679)
location: region:185528-186679:-1
so has part: feature:185528-186679:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:185528-186679:-1:exon

YJL125C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: TRM61
gene: GCD14
locus tag: YJL125C
gene synonym: TRM61
EC number: 2.1.1.220
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:9851972]
experiment: EXISTENCE:direct assay:GO:0016429 tRNA (adenine-N1-)-methyltransferase activity [PMID:10779558]
experiment: EXISTENCE:direct assay:GO:0030488 tRNA methylation [PMID:10779558]
experiment: EXISTENCE:direct assay:GO:0031515 tRNA (m1A) methyltransferase complex [PMID:10779558]
experiment: EXISTENCE:mutant phenotype:GO:0016429 tRNA (adenine-N1-)-methyltransferase activity [PMID:10779558]
experiment: EXISTENCE:physical interaction:GO:0031515 tRNA (m1A) methyltransferase complex [PMID:10779558]
note: Subunit of tRNA (1-methyladenosine) methyltransferase; required, along with Gcd10p, for the modification of the adenine at position 58 in tRNAs, especially tRNAi-Met; first identified as a negative regulator of GCN4 expression
codon start: 1
product: tRNA 1-methyladenosine methyltransferase subunit GCD14
translation: MSTNCFSGYKDLIKEGDLTLIWVSRDNIKPVRMHSEEVFNTRYGSFPHKDIIGKPYGSQIAIRTKGSNKFAFVHVLQPTPELWTLSLPHRTQIVYTPDSSYIMQRLNCSPHSRVIEAGTGSGSFSHAFARSVGHLFSFEFHHIRYEQALEEFKEHGLIDDNVTITHRDVCQGGFLIKKGDTTSYEFGNNETAASLNANVVFLDLPAPWDAIPHLDSVISVDEKVGLCCFSPCIEQVDKTLDVLEKYGWTDVEMVEIQGRQYESRRQMVRSLNDALERLRDIKRHKLQGVERRKRMFNNTIDSNDEKVGKRNEDGVPLTEKAKFNPFGKGSRIKEGDSNYKWKEVTKMEAEIKSHTSYLTFAFKVVNRSRDDEKVNEILRSTEK
SIO_010081: YJL125C
subclass of: SO_0000673
so part of: YJL125C
location: complement(185528..186679)
location: region:185528-186679:-1
so has part: feature:185528-186679:-1:exon

NP_012410.1
type: Protein
SIO_000068: ncbiprotein

S000003661
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:185528-186679:-1:exon

YJL124C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SPB8
gene: LSM1
locus tag: YJL124C
gene synonym: SPB8
so part of: sequence
location: complement(<187126..>187644)
location: region:187126-187644:-1
so has part: feature:187126-187644:-1:exon
subclass of: SO_0000010

853318
type: Gene
SIO_000068: ncbigene

position:187126:-1
position: 187126
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:187644:-1
position: 187644
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:187126-187644:-1:exon

YJL124C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SPB8
gene: LSM1
locus tag: YJL124C
gene synonym: SPB8
product: Lsm1p
transcript id: NM_001181557.1
SIO_010081: YJL124C
subclass of: SO_0000673
so part of: YJL124C
location: complement(<187126..>187644)
location: region:187126-187644:-1
so has part: feature:187126-187644:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:187126-187644:-1:exon

YJL124C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SPB8
gene: LSM1
locus tag: YJL124C
gene synonym: SPB8
experiment: EXISTENCE:direct assay:GO:0000932 P-body [PMID:12730603|PMID:18611963]
experiment: EXISTENCE:direct assay:GO:0003682 chromatin binding [PMID:23706738]
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:23706738]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:18029398|PMID:23706738|PMID:22842922]
experiment: EXISTENCE:direct assay:GO:1990726 Lsm1-7-Pat1 complex [PMID:24139796]
experiment: EXISTENCE:mutant phenotype:GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [PMID:10747033]
experiment: EXISTENCE:mutant phenotype:GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA [PMID:10761922]
experiment: EXISTENCE:mutant phenotype:GO:0000339 RNA cap binding [PMID:11741542]
experiment: EXISTENCE:mutant phenotype:GO:0000932 P-body [PMID:12730603]
note: Lsm (Like Sm) protein; forms heteroheptameric complex (with Lsm2p, Lsm3p, Lsm4p, Lsm5p, Lsm6p, and Lsm7p) involved in degradation of cytoplasmic mRNAs; also enters the nucleus and positively regulates transcription initiation; unlike most Sm-like proteins, Lsm1p requires both its SM-domain and C-terminal domain for RNA-binding; binds to mRNAs under glucose starvation, most often in the 3' UTR; forms cytoplasmic foci upon DNA replication stress
codon start: 1
product: Lsm1p
translation: MSANSKDRNQSNQDAKRQQQNFPKKISEGEADLYLDQYNFTTTAAIVSSVDRKIFVLLRDGRMLFGVLRTFDQYANLILQDCVERIYFSEENKYAEEDRGIFMIRGENVVMLGEVDIDKEDQPLEAMERIPFKEAWLTKQKNDEKRFKEETHKGKKMARHGIVYDFHKSDMY
SIO_010081: YJL124C
subclass of: SO_0000673
so part of: YJL124C
location: complement(187126..187644)
location: region:187126-187644:-1
so has part: feature:187126-187644:-1:exon

NP_012411.1
type: Protein
SIO_000068: ncbiprotein

S000003660
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:187126-187644:-1:exon

YJL123C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MTC1
locus tag: YJL123C
so part of: sequence
location: complement(<188004..>189440)
location: region:188004-189440:-1
so has part: feature:188004-189440:-1:exon
subclass of: SO_0000010

853319
type: Gene
SIO_000068: ncbigene

position:188004:-1
position: 188004
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:189440:-1
position: 189440
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:188004-189440:-1:exon

YJL123C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MTC1
locus tag: YJL123C
product: Mtc1p
transcript id: NM_001181556.1
SIO_010081: YJL123C
subclass of: SO_0000673
so part of: YJL123C
location: complement(<188004..>189440)
location: region:188004-189440:-1
so has part: feature:188004-189440:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:188004-189440:-1:exon

YJL123C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MTC1
locus tag: YJL123C
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:31323700]
experiment: EXISTENCE:direct assay:GO:0005794 Golgi apparatus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0030137 COPI-coated vesicle [PMID:14562095]
note: hypothetical protein that may interact with ribosomes; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to COPI-coated vesicles (early Golgi); mtc1 is synthetically lethal with cdc13-1
codon start: 1
product: Mtc1p
translation: MSENKNSEAEDVFEFLDSLPEAKNGGKMVNTDVKGSQEGVKGGSNSVAGKTGNDGKKGDDDIFEFLEELEKSNLSLTDKKGVEKKAPSESVNNKAQDEKVEESKENKNSEQDAHGKEKEPQQQEKEEEEEEEEEEEEEEEETPLHDPIASISNWWSSSGSAKVSSIWNKTAEQASQIKNRLAQEQLDLTSKINTSTITEIARNLQKIVVGETEEVLRIHLVHDLVNYPSLQYNIESKFDQVLSSQVEGGIRIFVDEWGHPNNNGITPVEKKPSVADGELGNSKKKLQFNLFDGKVTDGEKLAFANLENAVKLFNTAHEEYQKQQKEADATPDDDRSSISSNSNKISDLFISILPIAIPQKQKDADGDFQVTDSNTPGNFNFTLVLKDITNDITTITRSQGFPVKWVNWLEGSVEKTGSTASEERNKSYDQKKQKESEDEDEDDEIIDPSEWVKEWIEDGLSLSFGVMAQNYVIDRMGL
SIO_010081: YJL123C
subclass of: SO_0000673
so part of: YJL123C
location: complement(188004..189440)
location: region:188004-189440:-1
so has part: feature:188004-189440:-1:exon

NP_012412.1
type: Protein
SIO_000068: ncbiprotein

S000003659
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:188004-189440:-1:exon

YJL122W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ALB1
locus tag: YJL122W
so part of: sequence
location: <189716..>190243
location: region:189716-190243:1
so has part: feature:189716-190243:1:exon
subclass of: SO_0000010

853320
type: Gene
SIO_000068: ncbigene

position:189716:1
position: 189716
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:190243:1
position: 190243
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:189716-190243:1:exon

YJL122W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ALB1
locus tag: YJL122W
product: Alb1p
transcript id: NM_001181555.1
SIO_010081: YJL122W
subclass of: SO_0000673
so part of: YJL122W
location: <189716..>190243
location: region:189716-190243:1
so has part: feature:189716-190243:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:189716-190243:1:exon

YJL122W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ALB1
locus tag: YJL122W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:16651379|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:16651379]
experiment: EXISTENCE:genetic interaction:GO:0042273 ribosomal large subunit biogenesis [PMID:16651379]
experiment: EXISTENCE:physical interaction:GO:0042273 ribosomal large subunit biogenesis [PMID:16651379]
note: Shuttling pre-60S factor; involved in the biogenesis of ribosomal large subunit; interacts directly with Arx1p; responsible for Tif6p recycling defects in absence of Rei1p
codon start: 1
product: Alb1p
translation: MPSKNSINRPKLTSNLHHKVHSLNKKRAQRERAGLLKPARSSVNSKSGEIKSVALDLYFQNKKNESQNSTAVTLQNASSSPASITTRTLSKKRAKKIERNLKYATQRKLLVDASAKLEDEMDIDLDGGKKVKENEKKSSLTLVKEALWSVIDDTASQGLIIENGQGTTLGGPFFP
SIO_010081: YJL122W
subclass of: SO_0000673
so part of: YJL122W
location: 189716..190243
location: region:189716-190243:1
so has part: feature:189716-190243:1:exon

NP_012413.1
type: Protein
SIO_000068: ncbiprotein

S000003658
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:189716-190243:1:exon

YJL121C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: EPI1
alternative label: POS18
gene: RPE1
locus tag: YJL121C
gene synonym: EPI1; POS18
so part of: sequence
location: complement(<190374..>191090)
location: region:190374-191090:-1
so has part: feature:190374-191090:-1:exon
subclass of: SO_0000010

853322
type: Gene
SIO_000068: ncbigene

position:190374:-1
position: 190374
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:191090:-1
position: 191090
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:190374-191090:-1:exon

YJL121C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: EPI1
alternative label: POS18
gene: RPE1
locus tag: YJL121C
gene synonym: EPI1; POS18
product: ribulose-phosphate 3-epimerase RPE1
transcript id: NM_001181554.1
SIO_010081: YJL121C
subclass of: SO_0000673
so part of: YJL121C
location: complement(<190374..>191090)
location: region:190374-191090:-1
so has part: feature:190374-191090:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:190374-191090:-1:exon

YJL121C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: EPI1
alternative label: POS18
gene: RPE1
locus tag: YJL121C
gene synonym: EPI1; POS18
EC number: 5.1.3.1
experiment: EXISTENCE:direct assay:GO:0004750 D-ribulose-phosphate 3-epimerase activity [PMID:8929392]
experiment: EXISTENCE:mutant phenotype:GO:0004750 D-ribulose-phosphate 3-epimerase activity [PMID:8929392]
experiment: EXISTENCE:mutant phenotype:GO:0006098 pentose-phosphate shunt [PMID:8929392]
note: D-ribulose-5-phosphate 3-epimerase; catalyzes a reaction in the non-oxidative part of the pentose-phosphate pathway; mutants are sensitive to oxidative stress
codon start: 1
product: ribulose-phosphate 3-epimerase RPE1
translation: MVKPIIAPSILASDFANLGCECHKVINAGADWLHIDVMDGHFVPNITLGQPIVTSLRRSVPRPGDASNTEKKPTAFFDCHMMVENPEKWVDDFAKCGADQFTFHYEATQDPLHLVKLIKSKGIKAACAIKPGTSVDVLFELAPHLDMALVMTVEPGFGGQKFMEDMMPKVETLRAKFPHLNIQVDGGLGKETIPKAAKAGANVIVAGTSVFTAADPHDVISFMKEEVSKELRSRDLLD
SIO_010081: YJL121C
subclass of: SO_0000673
so part of: YJL121C
location: complement(190374..191090)
location: region:190374-191090:-1
so has part: feature:190374-191090:-1:exon

NP_012414.1
type: Protein
SIO_000068: ncbiprotein

S000003657
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:190374-191090:-1:exon

YJL118W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJL118W
so part of: sequence
location: <191639..>192298
location: region:191639-192298:1
so has part: feature:191639-192298:1:exon
subclass of: SO_0000010

853323
type: Gene
SIO_000068: ncbigene

position:191639:1
position: 191639
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:192298:1
position: 192298
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:191639-192298:1:exon

YJL118W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJL118W
product: uncharacterized protein
transcript id: NM_001181551.1
SIO_010081: YJL118W
subclass of: SO_0000673
so part of: YJL118W
location: <191639..>192298
location: region:191639-192298:1
so has part: feature:191639-192298:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:191639-192298:1:exon

YJL118W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJL118W
note: hypothetical protein; may interact with ribosomes, based on co-purification experiments; YJL118W is a non-essential gene; deletion enhances the toxicity of heterologously expressed human alpha-synuclein
codon start: 1
product: uncharacterized protein
translation: MASCFSVSLLARVAVVEPIRVQLWLNVVNCMIESSMHQCPPRDRHFFSSSRPILLIRRSVSTVYRFVASRTTQVLRAAKTVVKWFIIVDPLINSILINYLIDRLCTLGHAVLRVKKRKTEERQPCSPIIQHTHVKRRKRPRLRIVAIKRKRRRRRPHRIERPLSNMYPIMEIQMVAVPLALPSPTALVHYQQQQQQLPQHHPWYDLSLSEEALSTCCCS
SIO_010081: YJL118W
subclass of: SO_0000673
so part of: YJL118W
location: 191639..192298
location: region:191639-192298:1
so has part: feature:191639-192298:1:exon

NP_012417.1
type: Protein
SIO_000068: ncbiprotein

S000003654
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:191639-192298:1:exon

YJL117W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PHO86
locus tag: YJL117W
so part of: sequence
location: <192531..>193466
location: region:192531-193466:1
so has part: feature:192531-193466:1:exon
subclass of: SO_0000010

853325
type: Gene
SIO_000068: ncbigene

position:192531:1
position: 192531
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:193466:1
position: 193466
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:192531-193466:1:exon

YJL117W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PHO86
locus tag: YJL117W
product: Pho86p
transcript id: NM_001181550.1
SIO_010081: YJL117W
subclass of: SO_0000673
so part of: YJL117W
location: <192531..>193466
location: region:192531-193466:1
so has part: feature:192531-193466:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:192531-193466:1:exon

YJL117W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PHO86
locus tag: YJL117W
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:10655492|PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0006457 protein folding [PMID:15623581]
experiment: EXISTENCE:mutant phenotype:GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport [PMID:10655492]
experiment: EXISTENCE:mutant phenotype:GO:0010966 regulation of phosphate transport [PMID:10655492]
experiment: EXISTENCE:mutant phenotype:GO:0051082 unfolded protein binding [PMID:15623581]
note: Endoplasmic reticulum (ER) resident protein; required for ER exit of the high-affinity phosphate transporter Pho84p, specifically required for packaging of Pho84p into COPII vesicles; protein abundance increases in response to DNA replication stress
codon start: 1
product: Pho86p
translation: MAVQQRKKKEGRKSDKNAPSVPQVDASLDKPLDIDAPPTIYSVNLKPEYGTAALNLSADFIRQEQALANKYLFFHPVILVVLTIGLLIYLTPRIVFPIRNTGSVAGWFYQLARINKKVVLSGLVFTAIGASFLFTLLSRVSDSYFKSKINQLVGSKGEKVFGINLNDLVARHETKDPVVNNTHIIVYRETPIALISLAPNMTLSTDENLVMSVTTVGCRRVYVKSGIIEDLIDWAMLHSKNIRSSGKYGETMKLLIDVYSFDSTLKEILKKKGFTYIQSIRVSENRLLGGLFGVKKELWGLQFHFKAEHKD
SIO_010081: YJL117W
subclass of: SO_0000673
so part of: YJL117W
location: 192531..193466
location: region:192531-193466:1
so has part: feature:192531-193466:1:exon

NP_012418.1
type: Protein
SIO_000068: ncbiprotein

S000003653
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:192531-193466:1:exon

YJL116C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: NCA3
locus tag: YJL116C
so part of: sequence
location: complement(<193860..>194873)
location: region:193860-194873:-1
so has part: feature:193860-194873:-1:exon
subclass of: SO_0000010

853326
type: Gene
SIO_000068: ncbigene

position:193860:-1
position: 193860
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:194873:-1
position: 194873
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:193860-194873:-1:exon

YJL116C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: NCA3
locus tag: YJL116C
product: SUN family protein NCA3
transcript id: NM_001181549.1
SIO_010081: YJL116C
subclass of: SO_0000673
so part of: YJL116C
location: complement(<193860..>194873)
location: region:193860-194873:-1
so has part: feature:193860-194873:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:193860-194873:-1:exon

YJL116C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: NCA3
locus tag: YJL116C
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0042776 proton motive force-driven mitochondrial ATP synthesis [PMID:7586026]
note: Protein involved in mitochondrion organization; functions with Nca2p to regulate mitochondrial expression of subunits 6 (Atp6p) and 8 (Atp8p) of the Fo-F1 ATP synthase; SWAT-GFP, seamless-GFP and mCherry fusion proteins localize to the vacuole; member of the SUN family; expression induced in cells treated with the mycotoxin patulin; NCA3 has a paralog, UTH1, that arose from the whole genome duplication
codon start: 1
product: SUN family protein NCA3
translation: MKISAALILSSLSSVAFSAPAPAPADSHHEDHHKDEKPAVVTVTQYIDSNAATSTVESAATTTTLSSSEKDTSEQKRDGGFQDGTVKCSDFPSVNGIVSLDWLGFGGWASVMDMDANTSSECKDGYYCSYACEPGMSKTQWPSDQPSDGKSVGGLYCKNGYLYRTNTDTSDLCSTDETSAKAINKKSDSIALCRTDYPGSENMVIPTVVDGGDSQPISVVDEDTYYQWQGKKTSAQYYINNAGVSAEDGCIWGTSGSDVGNWAPLVLGAGSTNGETYLSLIPNPNSNQAANFNVKIVASDGANVQGSCAYEDGSFTGDGSDGCTVSVLSGSAEFVFY
SIO_010081: YJL116C
subclass of: SO_0000673
so part of: YJL116C
location: complement(193860..194873)
location: region:193860-194873:-1
so has part: feature:193860-194873:-1:exon

NP_012419.1
type: Protein
SIO_000068: ncbiprotein

S000003652
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:193860-194873:-1:exon

YJL115W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CIA1
gene: ASF1
locus tag: YJL115W
gene synonym: CIA1
so part of: sequence
location: <196287..>197126
location: region:196287-197126:1
so has part: feature:196287-197126:1:exon
subclass of: SO_0000010

853327
type: Gene
SIO_000068: ncbigene

position:196287:1
position: 196287
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:197126:1
position: 197126
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:196287-197126:1:exon

YJL115W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CIA1
gene: ASF1
locus tag: YJL115W
gene synonym: CIA1
product: nucleosome assembly factor ASF1
transcript id: NM_001181548.1
SIO_010081: YJL115W
subclass of: SO_0000673
so part of: YJL115W
location: <196287..>197126
location: region:196287-197126:1
so has part: feature:196287-197126:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:196287-197126:1:exon

YJL115W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CIA1
gene: ASF1
locus tag: YJL115W
gene synonym: CIA1
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:11404324|PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0006325 chromatin organization [PMID:16303565]
experiment: EXISTENCE:direct assay:GO:0006335 DNA replication-dependent chromatin assembly [PMID:11412995]
experiment: EXISTENCE:direct assay:GO:0032968 positive regulation of transcription elongation by RNA polymerase II [PMID:22308335]
experiment: EXISTENCE:direct assay:GO:0035066 positive regulation of histone acetylation [PMID:17272722|PMID:18458063]
experiment: EXISTENCE:genetic interaction:GO:0030466 silent mating-type cassette heterochromatin formation [PMID:15840725]
experiment: EXISTENCE:genetic interaction:GO:0031509 subtelomeric heterochromatin formation [PMID:15840725]
experiment: EXISTENCE:genetic interaction:GO:0035066 positive regulation of histone acetylation [PMID:18458063]
experiment: EXISTENCE:mutant phenotype:GO:0001932 regulation of protein phosphorylation [PMID:27222517]
experiment: EXISTENCE:mutant phenotype:GO:0006337 nucleosome disassembly [PMID:16678113]
experiment: EXISTENCE:mutant phenotype:GO:0006357 regulation of transcription by RNA polymerase II [PMID:19620280]
experiment: EXISTENCE:mutant phenotype:GO:0010468 regulation of gene expression [PMID:26941319]
experiment: EXISTENCE:mutant phenotype:GO:0016573 histone acetylation [PMID:16627621]
experiment: EXISTENCE:mutant phenotype:GO:0033523 histone H2B ubiquitination [PMID:24824343]
experiment: EXISTENCE:mutant phenotype:GO:0035066 positive regulation of histone acetylation [PMID:17272722|PMID:17679090|PMID:17690098|PMID:18458063]
experiment: EXISTENCE:mutant phenotype:GO:0042393 histone binding [PMID:15840725]
experiment: EXISTENCE:physical interaction:GO:0035066 positive regulation of histone acetylation [PMID:17690098]
note: Nucleosome assembly factor; involved in chromatin assembly, disassembly; required for recovery after DSB repair; role in H3K56 acetylation required for expression homeostasis, buffering mRNA synthesis rate against gene dosage changes in S phase; anti-silencing protein, derepresses silent loci when overexpressed; role in regulating Ty1 transposition; relocalizes to cytosol under hypoxia; growth defect of asf1 null is functionally complemented by either human ASF1A or ASF1B
codon start: 1
product: nucleosome assembly factor ASF1
translation: MSIVSLLGIKVLNNPAKFTDPYEFEITFECLESLKHDLEWKLTYVGSSRSLDHDQELDSILVGPVPVGVNKFVFSADPPSAELIPASELVSVTVILLSCSYDGREFVRVGYYVNNEYDEEELRENPPAKVQVDHIVRNILAEKPRVTRFNIVWDNENEGDLYPPEQPGVDDEEEEDDEEEDDDEDDEDDEDDDQEDGEGEAEEAAEEEEEEEEKTEDNETNLEEEEEDIENSDGDEEEGEEEVGSVDKNEDGNDKKRRKIEGGSTDIESTPKDAARSTN
SIO_010081: YJL115W
subclass of: SO_0000673
so part of: YJL115W
location: 196287..197126
location: region:196287-197126:1
so has part: feature:196287-197126:1:exon

NP_012420.1
type: Protein
SIO_000068: ncbiprotein

S000003651
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:196287-197126:1:exon

YNCJ0005C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCJ0005C
so part of: sequence
location: complement(197313..197385)
location: region:197313-197385:-1
so has part: feature:197313-197385:-1:exon
subclass of: SO_0000663

853328
type: Gene
SIO_000068: ncbigene

position:197313:-1
position: 197313
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:197385:-1
position: 197385
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:197313-197385:-1:exon

YNCJ0005C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCJ0005C
product: tRNA-Ala
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Alanine tRNA (tRNA-Ala), predicted by tRNAscan-SE analysis; one of 11 nuclear tRNA genes containing the tDNA-anticodon AGC (converted to IGC in the mature tRNA), decodes GCU and GCC codons into alanine, one of 16 nuclear tRNAs for alanine
SIO_010081: YNCJ0005C
subclass of: SO_0000673
so part of: YNCJ0005C
location: complement(197313..197385)
location: region:197313-197385:-1
so has part: feature:197313-197385:-1:exon

S000006514
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:197313-197385:-1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty3 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 197401..197494
location: region:197401-197494:1
so has part: feature:197401-197494:1:region

S000007035
type: SGD
SIO_000068: sgd

position:197401:1
position: 197401
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:197494:1
position: 197494
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:197401-197494:1:region

mobile_element
type: Mobile Element
subclass of: SO_0001037
RO_0002162: 559292
note: YJLWTy4-1; Ty4 element, LTR retrotransposon of the Copia (Pseudoviridae) group; contains co-transcribed genes TYA Gag and TYB Pol, encoding proteins involved in structure and function of virus-like particles, flanked by two direct repeats
mobile element type: retrotransposon:YJLWTy4-1
so part of: sequence
location: 197545..203768
location: region:197545-203768:1
so has part: feature:197545-203768:1:region

S000007039
type: SGD
SIO_000068: sgd

position:197545:1
position: 197545
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:203768:1
position: 203768
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:197545-203768:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty4 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 197545..197915
location: region:197545-197915:1
so has part: feature:197545-197915:1:region

S000007036
type: SGD
SIO_000068: sgd

position:197915:1
position: 197915
reference: sequence
type: ForwardStrandPosition
type: ExactPosition
type: FuzzyPosition

urn:…
SIO_000300: 1
SIO_000628: feature:197545-197915:1:region

YJL114W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJL114W
so part of: sequence
location: <197915..>198595
location: region:197915-198595:1
so has part: feature:197915-198595:1:exon
subclass of: SO_0000010

853329
type: Gene
SIO_000068: ncbigene

position:198595:1
position: 198595
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:197915-198595:1:exon

YJL114W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJL114W
product: gag protein
transcript id: NM_001181547.2
SIO_010081: YJL114W
subclass of: SO_0000673
so part of: YJL114W
location: <197915..>198595
location: region:197915-198595:1
so has part: feature:197915-198595:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:197915-198595:1:exon

YJL114W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJL114W
note: Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag
codon start: 1
product: gag protein
translation: MATPVRGETRNVIDDNISARIQSKVKTNDTVRQTPSSLRKVSIKDEQVRQYQRNLNRFKTILNGLKAEEEKLSEADDIQMLAEKLLKLGETIDKVENRIVDLVEKIQLLETNENNNILHEHIDATGTYYLFDTLTSTNKRFYPKDCVFDYRTNNVENIPILLNNFKKFIKKYQFDDVFENDIIEIDPRENEILCKIIKEGLGESLDIMNTNTTDIFRIIDGLKKQI
SIO_010081: YJL114W
subclass of: SO_0000673
so part of: YJL114W
location: 197915..198595
location: region:197915-198595:1
so has part: feature:197915-198595:1:exon

NP_012422.2
type: Protein
SIO_000068: ncbiprotein

S000003650
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:197915-198595:1:exon

YJL113W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJL113W
so part of: sequence
location: <198678..>203325
location: region:198678-203325:1
so has part: feature:198678-203325:1:exon
subclass of: SO_0000010

853330
type: Gene
SIO_000068: ncbigene

position:198678:1
position: 198678
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:203325:1
position: 203325
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:198678-203325:1:exon

YJL113W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJL113W
product: gag-pol fusion protein
transcript id: NM_001181546.3
SIO_010081: YJL113W
subclass of: SO_0000673
so part of: YJL113W
location: <198678..>203325
location: region:198678-203325:1
so has part: feature:198678-203325:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:198678-203325:1:exon

YJL113W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJL113W
EC number: 2.7.7.7
EC number: 2.7.7.49
EC number: 3.1.26.4
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:9448009]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
ribosomal slippage: true
note: Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes
codon start: 1
product: gag-pol fusion protein
translation: MNKLQKLVLMEKWIFSKCCQDCPNLKDYLQEAIMGTLHESLRNSVKQRLYNIPHDVGIDHEEFLINTVIETVIDLSPIADDQIENSCMYCKSVFHCSINCKKKPNRELGLTRPISQKPIIYKVHRDNNHLSPVQNEQKSWNKTQKRSNKVYNSKKLVIIDTGSGVNITNDKTLLHNYEDSNRSTRFFGIGKNSSVSVKGYGYIKIKNGHNNTDNKCLLTYYVPEEESTIISCYDLAKKTKMVLSRKYTRLGNKIIKIKTKIVNGVIHVKMNELIERPSDDSKINAIKPTSSPGFKLNKRSITLEDAHKRMGHTGIQQIENSIKHNHYEESLDLIKEPNEFWCQTCKISKATKRNHYTGSMNNHSTDHEPGSSWCMDIFGPVSSSNADTKRYMLIMVDNNTRYCMTSTHFNKNAETILAQVRKNIQYVETQFDRKVREINSDRGTEFTNDQIEEYFISKGIHHILTSTQDHAANGRAERYIRTIITDATTLLRQSNLRVKFWEYAVTSATNIRNYLEHKSTGKLPLKAISRQPVTVRLMSFLPFGEKGIIWNHNHKKLKPSGLPSIILCKDPNSYGYKFFIPSKNKIVTSDNYTIPNYTMDGRVRNTQNINKSHQFSSDNDDEEDQIETVTNLCEALENYEDDNKPITRLEDLFTEEELSQIDSNAKYPSPSNNLEGDLDYVFSDVEESGDYDVESELSTTNNSISTDKNKILSNKDFNSELASTEISISGIDKKGLINTSHIDEDKYDEKVHRIPSIIQEKLVGSKNTIKINDENKISDRIRSKNIGSILNTGLSRCVDITDESITNKDESMHNAKPELIQEQLKKTNHETSFPKEGSIGTNVKFRNTNNEISLKTGDTSLPIKTLESINNHHSNDYSTNKVEKFEKENHHPPPIEDIVDMSDQTDMESNCQDGNNLKELKVTDKNVPTDNGTNVSPRLEQNIEASGSPVQTVNKSAFLNKEFSSLNMKRKRKRHDKNNSLTSYELERDKKRSKKNRVKLIPDNMETVSAPKIRAIYYNEAISKNPDLKEKHEYKQAYHKELQNLKDMKVFDVDVKYSRSEIPDNLIVPTNTIFTKKRNGIYKARIVCRGDTQSPDTYSVITTESLNHNHIKIFLMIANNRNMFMKTLDINHAFLYAKLEEEIYIPHPHDRRCVVKLNKALYGLKQSPKEWNDHLRQYLNGIGLKDNSYTPGLYQTEDKNLMIAVYVDDCVIAASNEQRLDEFINKLKSNFELKITGTLIDDVLDTDILGMDLVYNKRLGTIDLTLKSFINRMDKKYNEELKKIRKSSIPHMSTYKIDPKKDVLQMSEEEFRQGVLKLQQLLGELNYVRHKCRYDIEFAVKKVARLVNYPHERVFYMIYKIIQYLVRYKDIGIHYDRDCNKDKKVIAITDASVGSEYDAQSRIGVILWYGMNIFNVYSNKSTNRCVSSTEAELHAIYEGYADSETLKVTLKELGEGDNNDIVMITDSKPAIQGLNRSYQQPKEKFTWIKTEIIKEKIKEKSIKLLKITGKGNIADLLTKPVSASDFKRFIQVLKNKITSQDILASTDY
SIO_010081: YJL113W
subclass of: SO_0000673
so part of: YJL113W
location: join(198678..198998,199000..203325)
location: region:198678-203325:1
so has part: feature:198678-198998:1:exon
so has part: feature:199000-203325:1:exon

NP_012421.2
type: Protein
SIO_000068: ncbiprotein

S000003649
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:198678-198998:1:exon

position:198998:1
position: 198998
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:199000-203325:1:exon

position:199000:1
position: 199000
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty4 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 203398..203768
location: region:203398-203768:1
so has part: feature:203398-203768:1:region

S000007037
type: SGD
SIO_000068: sgd

position:203398:1
position: 203398
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:203398-203768:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(203783..204114)
location: region:203783-204114:-1
so has part: feature:203783-204114:-1:region

S000007022
type: SGD
SIO_000068: sgd

position:203783:-1
position: 203783
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:204114:-1
position: 204114
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:203783-204114:-1:region

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1008; Autonomously Replicating Sequence
so part of: sequence
location: 204029..204917
location: region:204029-204917:1
so has part: feature:204029-204917:1:region

S000028445
type: SGD
SIO_000068: sgd

position:204029:1
position: 204029
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:204917:1
position: 204917
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:204029-204917:1:region

YNCJ0006W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCJ0006W
so part of: sequence
location: 204735..204806
location: region:204735-204806:1
so has part: feature:204735-204806:1:exon
subclass of: SO_0000663

853331
type: Gene
SIO_000068: ncbigene

position:204735:1
position: 204735
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:204806:1
position: 204806
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:204735-204806:1:exon

YNCJ0006W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCJ0006W
product: tRNA-Asp
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Aspartate tRNA (tRNA-Asp), predicted by tRNAscan-SE analysis
SIO_010081: YNCJ0006W
subclass of: SO_0000673
so part of: YNCJ0006W
location: 204735..204806
location: region:204735-204806:1
so has part: feature:204735-204806:1:exon

S000006536
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:204735-204806:1:exon

YJL112W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: GAG3
alternative label: NET2
gene: MDV1
locus tag: YJL112W
gene synonym: GAG3; NET2
so part of: sequence
location: <205305..>207449
location: region:205305-207449:1
so has part: feature:205305-207449:1:exon
subclass of: SO_0000010

853332
type: Gene
SIO_000068: ncbigene

position:205305:1
position: 205305
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:207449:1
position: 207449
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:205305-207449:1:exon

YJL112W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: GAG3
alternative label: NET2
gene: MDV1
locus tag: YJL112W
gene synonym: GAG3; NET2
product: Mdv1p
transcript id: NM_001181545.2
SIO_010081: YJL112W
subclass of: SO_0000673
so part of: YJL112W
location: <205305..>207449
location: region:205305-207449:1
so has part: feature:205305-207449:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:205305-207449:1:exon

YJL112W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: GAG3
alternative label: NET2
gene: MDV1
locus tag: YJL112W
gene synonym: GAG3; NET2
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005741 mitochondrial outer membrane [PMID:11038180|PMID:11038182|PMID:16407407]
experiment: EXISTENCE:direct assay:GO:0043130 ubiquitin binding [PMID:21070969]
experiment: EXISTENCE:genetic interaction:GO:0000266 mitochondrial fission [PMID:11179417]
experiment: EXISTENCE:genetic interaction:GO:0016559 peroxisome fission [PMID:18445678]
experiment: EXISTENCE:mutant phenotype:GO:0000002 mitochondrial genome maintenance [PMID:11038182]
experiment: EXISTENCE:mutant phenotype:GO:0000266 mitochondrial fission [PMID:11179417|PMID:11038180|PMID:11038182|PMID:11038183]
experiment: EXISTENCE:physical interaction:GO:0000266 mitochondrial fission [PMID:11038182|PMID:11179417]
note: Peripheral protein of cytosolic face of mitochondrial outer membrane; required for mitochondrial fission; interacts with Fis1p and with the self-assembled oligomeric form of the dynamin-related GTPase Dnm1p; contains WD repeats; MDV1 has a paralog, CAF4, that arose from the whole genome duplication
codon start: 1
product: Mdv1p
translation: MSVNDQITHIGKTLSTTASAFLNYQKSNSNTQDVLTNNGPYKNLLSNTVNNASSTSYFYKRTEHGRFVKNASNTFEDIYSKTRRGDVFRNKFTDNKTCFRMLTYISDDLLNEIPTKEGLKSDADGKLLTEGGENENLRKNASKKETSLFQGFKSYLPIAELAIENTERLNYDTNGTSGTVGAKDVMSKTNERDEIHTELPNFQDSFLIPPGVETKKISSSYSPSALKSFSQTLVNSLEFLNIQKNSTLSEIRDIEVEVENLRQKKEKLLGKIANIEQNQLLLEDNLKQIDDRLDFLEEYGLEVIEANSDENAEDDGMSERKALKNDAIRNEGVTTESISSEASNLPPRRRQQLRDDNSLNRLGAFYSKSKKRHRKSFPTFQQLYEPGTKIGSIMSTHDDFLTCLDFDAPFGTLCTAGYLDHTVKIWDLSKQNKIGELAGHLATINCMQINRDYGTLVTGGRDAALKLWNLNLAQQLYQETQNLTSPTNHIDSPCVHTFEAHTDEVTALSLDPSFLVSGSQDRTIRQWDLRSGKCLQTIDLSFANVLTTSTNVDLSKSTLLTQRNERPSIGALQSFDAALATGTKDGVVRLWDLRSGKVIRTLKGHTDAITSLKFDSACLVTGSYDRTVRIWDLRTGLLNKFHAYSAPVLSLDLFQENAAVVVADEPSVQIYDSEKDESWSCVEQGNETSVSTVKYKENYMVEGRENGDVNIWAV
SIO_010081: YJL112W
subclass of: SO_0000673
so part of: YJL112W
location: 205305..207449
location: region:205305-207449:1
so has part: feature:205305-207449:1:exon

NP_012423.1
type: Protein
SIO_000068: ncbiprotein

S000003648
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:205305-207449:1:exon

YJL111W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: TCP7
gene: CCT7
locus tag: YJL111W
gene synonym: TCP7
so part of: sequence
location: <207877..>209529
location: region:207877-209529:1
so has part: feature:207877-209529:1:exon
subclass of: SO_0000010

853333
type: Gene
SIO_000068: ncbigene

position:207877:1
position: 207877
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:209529:1
position: 209529
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:207877-209529:1:exon

YJL111W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: TCP7
gene: CCT7
locus tag: YJL111W
gene synonym: TCP7
product: chaperonin-containing T-complex subunit CCT7
transcript id: NM_001181544.1
SIO_010081: YJL111W
subclass of: SO_0000673
so part of: YJL111W
location: <207877..>209529
location: region:207877-209529:1
so has part: feature:207877-209529:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:207877-209529:1:exon

YJL111W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: TCP7
gene: CCT7
locus tag: YJL111W
gene synonym: TCP7
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005832 chaperonin-containing T-complex [PMID:16762366]
experiment: EXISTENCE:direct assay:GO:0006457 protein folding [PMID:16762366]
experiment: EXISTENCE:direct assay:GO:0051082 unfolded protein binding [PMID:16762366]
experiment: EXISTENCE:physical interaction:GO:0005832 chaperonin-containing T-complex [PMID:15704212]
note: Subunit of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo; mutant has increased aneuploidy tolerance
codon start: 1
product: chaperonin-containing T-complex subunit CCT7
translation: MNFGSQTPTIVVLKEGTDASQGKGQIISNINACVAVQEALKPTLGPLGSDILIVTSNQKTTISNDGATILKLLDVVHPAAKTLVDISRAQDAEVGDGTTSVTILAGELMKEAKPFLEEGISSHLIMKGYRKAVSLAVEKINELAVDITSEKSSGRELLERCARTAMSSKLIHNNADFFVKMCVDAVLSLDRNDLDDKLIGIKKIPGGAMEESLFINGVAFKKTFSYAGFEQQPKKFNNPKILSLNVELELKAEKDNAEVRVEHVEDYQAIVDAEWQLIFEKLRQVEETGANIVLSKLPIGDLATQFFADRNIFCAGRVSADDMNRVIQAVGGSIQSTTSDIKPEHLGTCALFEEMQIGSERYNLFQGCPQAKTCTLLLRGGAEQVIAEVERSLHDAIMIVKRALQNKLIVAGGGATEMEVSKCLRDYSKTIAGKQQMIINAFAKALEVIPRQLCENAGFDAIEILNKLRLAHSKGEKWYGVVFETENIGDNFAKFVWEPALVKINALNSATEATNLILSVDETITNKGSESANAGMMPPQGAGRGRGMPM
SIO_010081: YJL111W
subclass of: SO_0000673
so part of: YJL111W
location: 207877..209529
location: region:207877-209529:1
so has part: feature:207877-209529:1:exon

NP_012424.1
type: Protein
SIO_000068: ncbiprotein

S000003647
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:207877-209529:1:exon

YJL110C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: DEH1
alternative label: NIL2
gene: GZF3
locus tag: YJL110C
gene synonym: DEH1; NIL2
so part of: sequence
location: complement(<209922..>211577)
location: region:209922-211577:-1
so has part: feature:209922-211577:-1:exon
subclass of: SO_0000010

853334
type: Gene
SIO_000068: ncbigene

position:209922:-1
position: 209922
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:211577:-1
position: 211577
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:209922-211577:-1:exon

YJL110C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: DEH1
alternative label: NIL2
gene: GZF3
locus tag: YJL110C
gene synonym: DEH1; NIL2
product: Gzf3p
transcript id: NM_001181543.1
SIO_010081: YJL110C
subclass of: SO_0000673
so part of: YJL110C
location: complement(<209922..>211577)
location: region:209922-211577:-1
so has part: feature:209922-211577:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:209922-211577:-1:exon

YJL110C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: DEH1
alternative label: NIL2
gene: GZF3
locus tag: YJL110C
gene synonym: DEH1; NIL2
experiment: EXISTENCE:direct assay:GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific [PMID:19380492]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:19380492]
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:19111667|PMID:9171383]
experiment: EXISTENCE:genetic interaction:GO:0090295 nitrogen catabolite repression of transcription [PMID:9106207]
experiment: EXISTENCE:mutant phenotype:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:9171383]
experiment: EXISTENCE:mutant phenotype:GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific [PMID:19380492]
experiment: EXISTENCE:mutant phenotype:GO:0090295 nitrogen catabolite repression of transcription [PMID:9171383|PMID:9171427]
experiment: EXISTENCE:physical interaction:GO:0051457 maintenance of protein location in nucleus [PMID:19380492]
note: GATA zinc finger protein; negatively regulates nitrogen catabolic gene expression by competing with Gat1p for GATA site binding; function requires a repressive carbon source; dimerizes with Dal80p and binds to Tor1p; GZF3 has a paralog, DAL80, that arose from the whole genome duplication
codon start: 1
product: Gzf3p
translation: MASQATTLRGYNIRKRDNVFEPKSSENLNSLNQSEEEGHIGRWPPLGYEAVSAEQKSAVQLRESQAGASISNNMNFKANDKSFSTSTAGRMSPDTNSLHHILPKNQVKNNGQTMDANCNNNVSNDANVPVCKNCLTSTTPLWRRDEHGAMLCNACGLFLKLHGKPRPISLKTDVIKSRNRKSNTNHAHNLDNFRNQTLIAELKGDCNIESSGRKANRVTSEDKKKKSSQLLMGTSSTAKISKKPKTESKERSDSHLSATKLEVLMSGDCSRPNLKPKLPKQDTAIYQEKLLTFPSYTDVKEYSNSAHQSAFIKERSQFNAASFPLNASHSVTSKTGADSPQLPHLSMLLGSLSSTSISNNGSEIVSNCNNGIASTAATLAPTSSRTTDSNPSEVPNQIRSTMSSPDIISAKRNDPAPLSFHMASINDMLETRDRAISNVKTETTPPHFIPFLQSSKAPCISKANSQSISNSVSSSDVSGRKFENHPAKDLGDQLSTKLHKEEEIIKLKTRINELELVTDLYRRHINELDGKCRALEERLQRTVKQEGNKGG
SIO_010081: YJL110C
subclass of: SO_0000673
so part of: YJL110C
location: complement(209922..211577)
location: region:209922-211577:-1
so has part: feature:209922-211577:-1:exon

NP_012425.1
type: Protein
SIO_000068: ncbiprotein

S000003646
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:209922-211577:-1:exon

YJL109C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: UTP10
locus tag: YJL109C
so part of: sequence
location: complement(<212000..>217309)
location: region:212000-217309:-1
so has part: feature:212000-217309:-1:exon
subclass of: SO_0000010

853335
type: Gene
SIO_000068: ncbigene

position:212000:-1
position: 212000
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:217309:-1
position: 217309
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:212000-217309:-1:exon

YJL109C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: UTP10
locus tag: YJL109C
product: snoRNA-binding rRNA-processing protein UTP10
transcript id: NM_001181542.1
SIO_010081: YJL109C
subclass of: SO_0000673
so part of: YJL109C
location: complement(<212000..>217309)
location: region:212000-217309:-1
so has part: feature:212000-217309:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:212000-217309:-1:exon

YJL109C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: UTP10
locus tag: YJL109C
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:12068309|PMID:12150911|PMID:17652137|PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0030686 90S preribosome [PMID:17652137|PMID:12150911]
experiment: EXISTENCE:direct assay:GO:0030688 preribosome, small subunit precursor [PMID:17652137|PMID:15167894]
experiment: EXISTENCE:direct assay:GO:0032040 small-subunit processome [PMID:12068309]
experiment: EXISTENCE:direct assay:GO:0033553 rDNA heterochromatin [PMID:15489292]
experiment: EXISTENCE:direct assay:GO:0034455 t-UTP complex [PMID:17515605]
experiment: EXISTENCE:direct assay:GO:0034511 U3 snoRNA binding [PMID:12068309]
experiment: EXISTENCE:mutant phenotype:GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:17652137]
experiment: EXISTENCE:mutant phenotype:GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:12068309]
experiment: EXISTENCE:mutant phenotype:GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:17652137]
experiment: EXISTENCE:mutant phenotype:GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:17652137]
experiment: EXISTENCE:mutant phenotype:GO:0045943 positive regulation of transcription by RNA polymerase I [PMID:15489292]
note: Nucleolar protein; component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA; mutant has increased aneuploidy tolerance
codon start: 1
product: snoRNA-binding rRNA-processing protein UTP10
translation: MSSLSDQLAQVASNNATVALDRKRRQKLHSASLIYNSKTAATQDYDFIFENASKALEELSQIEPKFAIFSRTLFSESSISLDRNVQTKEEIKDLDNAINAYLLLASSKWYLAPTLHATEWLVRRFQIHVKNTEMLLLSTLNYYQTPVFKRILSIIKLPPLFNCLSNFVRSEKPPTALTMIKLFNDMDFLKLYTSYLDQCIKHNATYTNQLLFTTCCFINVVAFNSNNDEKLNQLVPILLEISAKLLASKSKDCQIAAHTILVVFATALPLKKTIILAAMETILSNLDAKEAKHSALLTICKLFQTLKGQGNVDQLPSKIFKLFDSKFDTVSILTFLDKEDKPVCDKFITSYTRSIARYDRSKLNIILSLLKKIRLERYEVRLIITDLIYLSEILEDKSQLVELFEYFISINEDLVLKCLKSLGLTGELFEIRLTTSLFTNADVNTDIVKQLSDPVETTKKDTASFQTFLDKHSELINTTNVSMLTETGERYKKVLSLFTEAIGKGYKASSFLTSFFTTLESRITFLLRVTISPAAPTALKLISLNNIAKYINSIEKEVNIFTLVPCLICALRDASIKVRTGVKKILSLIAKRPSTKHYFLSDKLYGENVTIPMLNPKDSEAWLSGFLNEYVTENYDISRILTPKRNEKVFLMFWANQALLIPSPYAKTVLLDNLNKSPTYASSYSSLFEEFISHYLENRSSWEKSCIANKTNFEHFERSLVNLVSPKEKQSFMIDFVLSALNSDYEQLANIAAERLISIFASLNNAQKLKIVQNIVDSSSNVESSYDTVGVLQSLPLDSDIFVSILNQNSISNEMDQTDFSKRRRRRSSTSKNAFLKEEVSQLAELHLRKLTIILEALDKVRNVGSEKLLFTLLSLLSDLETLDQDGGLPVLYAQETLISCTLNTITYLKEHGCTELTNVRADILVSAIRNSASPQVQNKLLLVIGSLATLSSEVILHSVMPIFTFMGAHSIRQDDEFTTKVVERTILTVVPALIKNSKGNEKEEMEFLLLSFTTALQHVPRHRRVKLFSTLIKTLDPVKALGSFLFLIAQQYSSALVNFKIGEARILIEFIKALLVDLHVNEELSGLNDLLDIIKLLTSSKSSSEKKKSLESRVLFSNGVLNFSESEFLTFMNNTFEFINKITEETDQDYYDVRRNLRLKVYSVLLDETSDKKLIRNIREEFGTLLEGVLFFINSVELTFSCITSQENEEASDSETSLSDHTTEIKEILFKVLGNVLQILPVDEFVNAVLPLLSTSTNEDIRYHLTLVIGSKFELEGSEAIPIVNNVMKVLLDRMPLESKSVVISQVILNTMTALVSKYGKKLEGSILTQALTLATEKVSSDMTEVKISSLALITNCVQVLGVKSIAFYPKIVPPSIKLFDASLADSSNPLKEQLQVAILLLFAGLIKRIPSFLMSNILDVLHVIYFSREVDSSIRLSVISLIIENIDLKEVLKVLFRIWSTEIATSNDTVAVSLFLSTLESTVENIDKKSATSQSPIFFKLLLSLFEFRSISSFDNNTISRIEASVHEISNSYVLKMNDKVFRPLFVILVRWAFDGEGVTNAGITETERLLAFFKFFNKLQENLRGIITSYFTYLLEPVDMLLKRFISKDMENVNLRRLVINSLTSSLKFDRDEYWKSTSRFELISVSLVNQLSNIENSIGKYLVKAIGALASNNSGVDEHNQILNKLIVEHMKASCSSNEKLWAIRAMKLIYSKIGESWLVLLPQLVPVIAELLEDDDEEIEREVRTGLVKVVENVLGEPFDRYLD
SIO_010081: YJL109C
subclass of: SO_0000673
so part of: YJL109C
location: complement(212000..217309)
location: region:212000-217309:-1
so has part: feature:212000-217309:-1:exon

NP_012426.1
type: Protein
SIO_000068: ncbiprotein

S000003645
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:212000-217309:-1:exon

YJL108C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PRM10
locus tag: YJL108C
so part of: sequence
location: complement(<217705..>218856)
location: region:217705-218856:-1
so has part: feature:217705-218856:-1:exon
subclass of: SO_0000010

853336
type: Gene
SIO_000068: ncbigene

position:217705:-1
position: 217705
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:218856:-1
position: 218856
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:217705-218856:-1:exon

YJL108C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PRM10
locus tag: YJL108C
product: pheromone-regulated protein PRM10
transcript id: NM_001181541.1
SIO_010081: YJL108C
subclass of: SO_0000673
so part of: YJL108C
location: complement(<217705..>218856)
location: region:217705-218856:-1
so has part: feature:217705-218856:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:217705-218856:-1:exon

YJL108C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PRM10
locus tag: YJL108C
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
note: Pheromone-regulated protein; proposed to be involved in mating; predicted to have 5 transmembrane segments; induced by treatment with 8-methoxypsoralen and UVA irradiation
codon start: 1
product: pheromone-regulated protein PRM10
translation: MIVSFGDATTRTSEVQLVRCTQGLNLWKLHQVHAVYKRVVHDTLGADEGNALLDQILADTNLYPPWMCVLLYAFCSAMVTPYAFGGDWVNLAISFFMGLCVGSLQFILSQKSYMYSNVFEISASIVVSFCGRAFGSIPRSHICFGAVTQGSLALILPGYIILCGALELQSRSLVAGAVRMFYAIIYSLFLGFGITLGSALFGWMYHNATNEISCPQLISPWFRFLFVPAFTISISLLNQAHISQLPVMVFISCTGYVVTYWAGKHFANSTEFTAALAAFVIGVLGNLYSRIWKGLAVSAMLPAIFVQVPSGIASQNSLLSGLQSANTIVNANETITTSTSDPSSSMSFGMTMIQVCVGISVGLFASSLFVYPFGKKKTGLFSL
SIO_010081: YJL108C
subclass of: SO_0000673
so part of: YJL108C
location: complement(217705..218856)
location: region:217705-218856:-1
so has part: feature:217705-218856:-1:exon

NP_012427.1
type: Protein
SIO_000068: ncbiprotein

S000003644
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:217705-218856:-1:exon

YJL107C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJL107C
so part of: sequence
location: complement(<218853..>220016)
location: region:218853-220016:-1
so has part: feature:218853-220016:-1:exon
subclass of: SO_0000010

853337
type: Gene
SIO_000068: ncbigene

position:218853:-1
position: 218853
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:220016:-1
position: 220016
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:218853-220016:-1:exon

YJL107C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJL107C
product: uncharacterized protein
transcript id: NM_001181540.1
SIO_010081: YJL107C
subclass of: SO_0000673
so part of: YJL107C
location: complement(<218853..>220016)
location: region:218853-220016:-1
so has part: feature:218853-220016:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:218853-220016:-1:exon

YJL107C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJL107C
note: hypothetical protein; expression is induced by activation of the HOG1 mitogen-activated signaling pathway and this induction is Hog1p/Pbs2p dependent; YJL107C and adjacent ORF, YJL108C are merged in related fungi
codon start: 1
product: uncharacterized protein
translation: MDGRNEKPTTPVSDFRVGSSEQSQAGVNLEDSSDHRTSNSAESKKGNLSGKSISDLGISNNDNKNVRFTADTDALENDLSSRSTETSDNSKGTDGQDEEDRPARHKRKPKVSFTHLRNNGKDGDDETFIKKIINNLTGNQGGLVPGLAPIPSENENGKNDIEKNNRNEEIPLSDLADASKIVDVHEGDDKEKLEALKLEGDVNCTSDGETLGSSSKNSFLAPAVDHFDDYAENNSSDDNEGFIETSTYVPPPSQVKSGVLGSLLKLYQNEDQNSSSIFSDSQAVTTDDEGISSTAGNKDVPVAKRSRLQNLKGKAKKGRMPRLKKRLKTEAKITVHIADILQRHRFILRMCRALMMYGAPTHRLEEYMVMTSRVLEIDGQFCIFQVV
SIO_010081: YJL107C
subclass of: SO_0000673
so part of: YJL107C
location: complement(218853..220016)
location: region:218853-220016:-1
so has part: feature:218853-220016:-1:exon

NP_012428.1
type: Protein
SIO_000068: ncbiprotein

S000003643
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:218853-220016:-1:exon

YJL106W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SME1
gene: IME2
locus tag: YJL106W
gene synonym: SME1
so part of: sequence
location: <221390..>223327
location: region:221390-223327:1
so has part: feature:221390-223327:1:exon
subclass of: SO_0000010

853338
type: Gene
SIO_000068: ncbigene

position:221390:1
position: 221390
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:223327:1
position: 223327
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:221390-223327:1:exon

YJL106W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SME1
gene: IME2
locus tag: YJL106W
gene synonym: SME1
product: protein kinase IME2
transcript id: NM_001181539.1
SIO_010081: YJL106W
subclass of: SO_0000673
so part of: YJL106W
location: <221390..>223327
location: region:221390-223327:1
so has part: feature:221390-223327:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:221390-223327:1:exon

YJL106W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SME1
gene: IME2
locus tag: YJL106W
gene synonym: SME1
EC number: 2.7.11.1
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:7764269|PMID:16319894]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:7764269]
experiment: EXISTENCE:genetic interaction:GO:1902596 negative regulation of DNA replication origin binding [PMID:29388912]
experiment: EXISTENCE:mutant phenotype:GO:0040020 regulation of meiotic nuclear division [PMID:9003314]
experiment: EXISTENCE:mutant phenotype:GO:1902596 negative regulation of DNA replication origin binding [PMID:29388912]
note: Serine/threonine protein kinase involved in activation of meiosis; associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p; human CDK2 can complement ime2 null mutant
codon start: 1
product: protein kinase IME2
translation: MVEKRSRQSSSSGSEFSVPPDVDNPPLSIPLKTLSDRYQLIEKLGAGSFGCVTLAKAQFPLSNILGKQHDIRGTLMDQPKNGHQNYITKTQGVVAIKTMMTKLHTLQDYTRVREIKFILAIPANDHLIQIFEVFIDSENYQLHIVMECMEQNLYQMMKHRRRRVFSIPSLKSILSQILAGLKHIHEHNFFHRDLKPENILITPSTQYFEKEYMNQIGYQDNYVIKLADFGLARHVENKNPYTAYVSTRWYRSPEILLRSGYYSKPLDIWAFGCVAVEVTVFRALFPGANEIDQIWKILEVLGTPIKRSDFVNTNHITAPPPGGFWDDASNLVHKLNLKLPYVEGSSLDHLLSSSQLSDLSEVVKKCLRWDPNERATAQELCEMPFFENTVASQVDARGNVTNTEQALIFAGINPVATNTKPIYFNSSTKLPAETESNDIDISNNDHDSHAMCSPTLNQEKLTLVEFLNEFVEEDNDDHSIPDVGTDSTISDSIDETELSKEIRNNLALCQLPDEEVLDHSLSNIRQLTNDIEIINKDEADNMEQLFFDLEIPEKDEFQRKQPFNEHADIDEDIVLPYVNNSNYTHTDRSHHRGDNVLGDASLGDSFNSMPDFTPRNFLIPTLKKSREKFEPHLSNSNQHFGNVTF
SIO_010081: YJL106W
subclass of: SO_0000673
so part of: YJL106W
location: 221390..223327
location: region:221390-223327:1
so has part: feature:221390-223327:1:exon

NP_012429.1
type: Protein
SIO_000068: ncbiprotein

S000003642
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:221390-223327:1:exon

YJL105W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SET4
locus tag: YJL105W
so part of: sequence
location: <225055..>226737
location: region:225055-226737:1
so has part: feature:225055-226737:1:exon
subclass of: SO_0000010

853339
type: Gene
SIO_000068: ncbigene

position:225055:1
position: 225055
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:226737:1
position: 226737
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:225055-226737:1:exon

YJL105W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SET4
locus tag: YJL105W
product: Set4p
transcript id: NM_001181538.1
SIO_010081: YJL105W
subclass of: SO_0000673
so part of: YJL105W
location: <225055..>226737
location: region:225055-226737:1
so has part: feature:225055-226737:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:225055-226737:1:exon

YJL105W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SET4
locus tag: YJL105W
experiment: EXISTENCE:direct assay:GO:0035065 regulation of histone acetylation [PMID:34625508]
experiment: EXISTENCE:mutant phenotype:GO:1900407 regulation of cellular response to oxidative stress [PMID:30082318]
note: Chromatin-associated protein involved in control of stress response; regulates response to oxidative stress; involved in control of gene repression in subtelomeric chromatin; contains a SET domain; SET4 has a paralog, SET3, that arose from the whole genome duplication
codon start: 1
product: Set4p
translation: MTSPESLSSRHIRQGRTYTTTDKVISRSSSYSSNSSMSKDYGDHTPLSVSSAASETLPSPQYMPIRTFNTMPTAGPTPLHLFQNDRGIFNHHSSSGSSKTASTNKRGIAAAVALATAATIPFPLKKQNQDDNSKVSVTHNESSKENKITPSMRAEDNKPKNGCICGSSDSKDELFIQCNKCKTWQHKLCYAFKKSDPIKRDFVCKRCDSDTKVQVNQVKPMIFPRKMGDERLFQFSSIVTTSASNTNQHQQSVNNIEEQPKKRQLHYTAPTTENSNSIRKKLRQEKLVVSSHFLKPLLNEVSSSNDTEFKAITISEYKDKYVKMFIDNHYDDDWVVCSNWESSRSADIEVRKSSNERDFGVFAADSCVKGELIQEYLGKIDFQKNYQTDPNNDYRLMGTTKPKVLFHPHWPLYIDSRETGGLTRYIRRSCEPNVELVTVRPLDEKPRGDNDCRVKFVLRAIRDIRKGEEISVEWQWDLRNPIWEIINASKDLDSLPDPDKFWLMGSIKTILTNCDCACGYLGHNCPITKIKNFSEEFMRNTKESLSNKSYFNTIMHNCKP
SIO_010081: YJL105W
subclass of: SO_0000673
so part of: YJL105W
location: 225055..226737
location: region:225055-226737:1
so has part: feature:225055-226737:1:exon

NP_012430.1
type: Protein
SIO_000068: ncbiprotein

S000003641
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:225055-226737:1:exon

YJL104W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MIA1
alternative label: TIM16
gene: PAM16
locus tag: YJL104W
gene synonym: MIA1; TIM16
so part of: sequence
location: <227327..>227776
location: region:227327-227776:1
so has part: feature:227327-227776:1:exon
subclass of: SO_0000010

853340
type: Gene
SIO_000068: ncbigene

position:227327:1
position: 227327
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:227776:1
position: 227776
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:227327-227776:1:exon

YJL104W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MIA1
alternative label: TIM16
gene: PAM16
locus tag: YJL104W
gene synonym: MIA1; TIM16
product: import motor complex subunit PAM16
transcript id: NM_001181537.1
SIO_010081: YJL104W
subclass of: SO_0000673
so part of: YJL104W
location: <227327..>227776
location: region:227327-227776:1
so has part: feature:227327-227776:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:227327-227776:1:exon

YJL104W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MIA1
alternative label: TIM16
gene: PAM16
locus tag: YJL104W
gene synonym: MIA1; TIM16
experiment: EXISTENCE:direct assay:GO:0001405 PAM complex, Tim23 associated import motor [PMID:14981506|PMID:14981507]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095|PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005744 TIM23 mitochondrial import inner membrane translocase complex [PMID:14981506]
experiment: EXISTENCE:direct assay:GO:0019904 protein domain specific binding [PMID:16105940]
experiment: EXISTENCE:mutant phenotype:GO:0030150 protein import into mitochondrial matrix [PMID:14981506|PMID:14981507]
note: Subunit of the import motor (PAM complex); the PAM complex is a component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); forms a 1:1 subcomplex with Pam18p and inhibits its cochaperone activity; contains a J-like domain
codon start: 1
product: import motor complex subunit PAM16
translation: MAHRAFIQVIITGTQVFGKAFAEAYRQAASQSVKQGATNASRRGTGKGEYGGITLDESCKILNIEESKGDLNMDKINNRFNYLFEVNDKEKGGSFYLQSKVYRAAERLKWELAQREKNAKAKAGDASTAKPPPNSTNSSGADNSASSNQ
SIO_010081: YJL104W
subclass of: SO_0000673
so part of: YJL104W
location: 227327..227776
location: region:227327-227776:1
so has part: feature:227327-227776:1:exon

NP_012431.1
type: Protein
SIO_000068: ncbiprotein

S000003640
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:227327-227776:1:exon

YNCJ0007C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SNR37
locus tag: YNCJ0007C
so part of: sequence
location: complement(228094..228479)
location: region:228094-228479:-1
so has part: feature:228094-228479:-1:exon
subclass of: SO_0000578

9164908
type: Gene
SIO_000068: ncbigene

position:228094:-1
position: 228094
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:228479:-1
position: 228479
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:228094-228479:-1:exon

YNCJ0007C
type: Non Coding RNA
subclass of: SO_0000655
RO_0002162: 559292
nc RNA class: snoRNA
gene: SNR37
locus tag: YNCJ0007C
product: SNR37
experiment: EXISTENCE:curator inference:GO:0005730 nucleolus [PMID:9160748]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:35385737]
experiment: EXISTENCE:mutant phenotype:GO:0030559 rRNA pseudouridylation guide activity [PMID:9160748|PMID:35385737]
experiment: EXISTENCE:mutant phenotype:GO:0031118 rRNA pseudouridine synthesis [PMID:9160748]
experiment: EXISTENCE:mutant phenotype:GO:0042254 ribosome biogenesis [PMID:35385737]
experiment: EXISTENCE:physical interaction:GO:0031429 box H/ACA snoRNP complex [PMID:15923376|PMID:9472021]
note: H/ACA box small nucleolar RNA (snoRNA) involved in ribosome synthesis; has structural role in early pre-60S pathway; guides pseudouridylation of large subunit (LSU) rRNA at position U2944
transcript id: NR_132195.1
SIO_010081: YNCJ0007C
subclass of: SO_0000673
so part of: YNCJ0007C
location: complement(228094..228479)
location: region:228094-228479:-1
so has part: feature:228094-228479:-1:exon

S000006501
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:228094-228479:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1009; Autonomously Replicating Sequence
so part of: sequence
location: 228552..229043
location: region:228552-229043:1
so has part: feature:228552-229043:1:region

S000028446
type: SGD
SIO_000068: sgd

position:228552:1
position: 228552
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:229043:1
position: 229043
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:228552-229043:1:region

YJL103C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GSM1
locus tag: YJL103C
so part of: sequence
location: complement(<229025..>230881)
location: region:229025-230881:-1
so has part: feature:229025-230881:-1:exon
subclass of: SO_0000010

853341
type: Gene
SIO_000068: ncbigene

position:229025:-1
position: 229025
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:230881:-1
position: 230881
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:229025-230881:-1:exon

YJL103C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GSM1
locus tag: YJL103C
product: Gsm1p
transcript id: NM_001181536.1
SIO_010081: YJL103C
subclass of: SO_0000673
so part of: YJL103C
location: complement(<229025..>230881)
location: region:229025-230881:-1
so has part: feature:229025-230881:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:229025-230881:-1:exon

YJL103C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GSM1
locus tag: YJL103C
experiment: EXISTENCE:curator inference:GO:0005634 nucleus [PMID:16785442]
experiment: EXISTENCE:direct assay:GO:0003700 DNA-binding transcription factor activity [PMID:16785442]
experiment: EXISTENCE:direct assay:GO:0006357 regulation of transcription by RNA polymerase II [PMID:16785442]
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:19158363]
experiment: EXISTENCE:mutant phenotype:GO:0003700 DNA-binding transcription factor activity [PMID:16785442]
experiment: EXISTENCE:mutant phenotype:GO:0006357 regulation of transcription by RNA polymerase II [PMID:16785442]
note: Putative zinc cluster hypothetical protein; proposed to be involved in the regulation of energy metabolism, based on patterns of expression and sequence analysis
codon start: 1
product: Gsm1p
translation: MTKKLPSELKQTRKSIQTACEFCHTKHIQCDVGRPCQNCLKRNIGKFCRDKKRKSRKRIEKHGTQPYLNLGKRLVIHDVPSKTVSPSSVHLQRDFLSSDQEKPGKTPAHNTNIQYTYNINDNFQSAGSIPRITNFNTNNRQTVLENTSNNISASQAVHLMNDPIIPTVRKSTLNLKSHFLEQHKAMQQPLATNCLVATSNVPVHSGMDDSNKSDDDVDDETNIHFDSMWCNDEYMKLKDIVDISTPFLPNNSQIFSLQESEYPNPSASTRGNSSLHLTNLLNSTKSVNDQKDSSIGHSTSTFNTYDEVVSRPFISLDMLHLNRGANANTHPSHNAKLESECDSSSHSDADLEKHDTDFISPSKFRELVKTPQDLYDNKCLIKPHNYKLAYTKLLTTLRKKFLEGAEIDKSASVKDEHSTQKHNLRYDLEVIIRSILERYAPIFISLTSNMIEEDLLLQEVTLQRALLDLENMAKLVSCTPMCIWRRSGEICFVSNEFYSLTGFNKNLLLDRTSFIFEYLDHKSVSNYFQIFNELLAFGYNDINKRKKLLMLNACSSTSSKITEGFSFTTDGKAIFTKCNLLLSNGLYLKCACCWTVKRDSFNIPILVMGQFLPIFEMD
SIO_010081: YJL103C
subclass of: SO_0000673
so part of: YJL103C
location: complement(229025..230881)
location: region:229025-230881:-1
so has part: feature:229025-230881:-1:exon

NP_012432.1
type: Protein
SIO_000068: ncbiprotein

S000003639
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:229025-230881:-1:exon

YJL102W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MEF2
locus tag: YJL102W
so part of: sequence
location: <231301..>233760
location: region:231301-233760:1
so has part: feature:231301-233760:1:exon
subclass of: SO_0000010

853342
type: Gene
SIO_000068: ncbigene

position:231301:1
position: 231301
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:233760:1
position: 233760
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:231301-233760:1:exon

YJL102W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MEF2
locus tag: YJL102W
product: Mef2p
transcript id: NM_001181535.1
SIO_010081: YJL102W
subclass of: SO_0000673
so part of: YJL102W
location: <231301..>233760
location: region:231301-233760:1
so has part: feature:231301-233760:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:231301-233760:1:exon

YJL102W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MEF2
locus tag: YJL102W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0000002 mitochondrial genome maintenance [PMID:21414316]
experiment: EXISTENCE:mutant phenotype:GO:0051881 regulation of mitochondrial membrane potential [PMID:21414316]
note: Mitochondrial elongation factor involved in translational elongation
codon start: 1
product: Mef2p
translation: MWKWNVRRWAGARVNISKNRLSVINVGSRYLSTARSPLSKVRNIGIIAHIDAGKTTTTERMLYYAGISKHIGDVDTGDTITDFLEQERSRGITIQSAAISFPWRNTFAINLIDTPGHIDFTFEVIRALKVIDSCVVILDAVAGVEAQTEKVWKQSKSKPKICFINKMDRMGASFNHTVNDLINKFMRGTTTKPVLVNIPYYRKQPTSNDYVFQGVIDVVNGKRLTWNPENPDEIIVDELDGTSLEQCNRCRESMIETLTEYDEDLVQHFLEEAEGDYSKVSAQFLNASIRKLTMKNMIVPVLCGASFKNIGVQPLLDAIVNYLPSPIEAELPELNDKTVPMKYDPKVGCLVNNNKNLCIALAFKVITDPIRGKQIFIRIYSGTLNSGNTVYNSTTGEKFKLGKLLIPHAGTSQPVNILTAGQIGLLTGSTVENNISTGDTLITHSSKKDGLKSLDKKKELTLKINSIFIPPPVFGVSIEPRTLSNKKSMEEALNTLITEDPSLSISQNDETGQTVLNGMGELHLEIAKDRLVNDLKADVEFGQLMVSYKETINSETNIETYESDDGYRFSLSLLPNSDALPNCLAYPLGVNENFLIMEKNGNWDKEWKYQVSFESILNSIIASCIVGLQRGGKIANFPLYACSIKINSDWSVPPDIETPQEILKITRNLIFKALNDLKPEKYNLLEPIMNLDLTIPQSDVGTVLQDLTGARKAQILSIEDESSVSNSGASTCNSPENSNRIYIPSDAVTTLHATKDKKNTQETSSNVKKIIKAKVPLREITTYTNKLRSLSQGRGEFNIEYSDMEKVTNDRLQSILHDL
SIO_010081: YJL102W
subclass of: SO_0000673
so part of: YJL102W
location: 231301..233760
location: region:231301-233760:1
so has part: feature:231301-233760:1:exon

NP_012433.1
type: Protein
SIO_000068: ncbiprotein

S000003638
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:231301-233760:1:exon

YNCJ0008W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCJ0008W
so part of: sequence
location: 233939..234011
location: region:233939-234011:1
so has part: feature:233939-234011:1:exon
subclass of: SO_0000663

853343
type: Gene
SIO_000068: ncbigene

position:233939:1
position: 233939
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:234011:1
position: 234011
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:233939-234011:1:exon

YNCJ0008W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCJ0008W
product: tRNA-Arg
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Arginine tRNA (tRNA-Arg), predicted by tRNAscan-SE analysis; one of 6 nuclear tRNA genes containing the tDNA-anticodon ACG (converted to ICG in the mature tRNA), decodes CGU, CGC, and probably CGA codons into arginine, one of 19 nuclear tRNAs for arginine
SIO_010081: YNCJ0008W
subclass of: SO_0000673
so part of: YNCJ0008W
location: 233939..234011
location: region:233939-234011:1
so has part: feature:233939-234011:1:exon

S000006702
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:233939-234011:1:exon

YJL101C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GSH1
locus tag: YJL101C
so part of: sequence
location: complement(<234320..>236356)
location: region:234320-236356:-1
so has part: feature:234320-236356:-1:exon
subclass of: SO_0000010

853344
type: Gene
SIO_000068: ncbigene

position:234320:-1
position: 234320
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:236356:-1
position: 236356
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:234320-236356:-1:exon

YJL101C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GSH1
locus tag: YJL101C
product: glutamate--cysteine ligase
transcript id: NM_001181534.1
SIO_010081: YJL101C
subclass of: SO_0000673
so part of: YJL101C
location: complement(<234320..>236356)
location: region:234320-236356:-1
so has part: feature:234320-236356:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:234320-236356:-1:exon

YJL101C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GSH1
locus tag: YJL101C
EC number: 6.3.2.2
experiment: EXISTENCE:direct assay:GO:0004357 glutamate-cysteine ligase activity [PMID:1687097]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:2184310]
experiment: EXISTENCE:direct assay:GO:0006750 glutathione biosynthetic process [PMID:1687097]
experiment: EXISTENCE:direct assay:GO:0046686 response to cadmium ion [PMID:10921921]
experiment: EXISTENCE:mutant phenotype:GO:0004357 glutamate-cysteine ligase activity [PMID:2184310]
experiment: EXISTENCE:mutant phenotype:GO:0006750 glutathione biosynthetic process [PMID:8768524]
experiment: EXISTENCE:mutant phenotype:GO:0042542 response to hydrogen peroxide [PMID:7615092]
note: Gamma glutamylcysteine synthetase; catalyzes the first step in glutathione (GSH) biosynthesis; expression induced by oxidants, cadmium, and mercury; protein abundance increases in response to DNA replication stress
codon start: 1
product: glutamate--cysteine ligase
translation: MGLLALGTPLQWFESRTYNEHIRDEGIEQLLYIFQAAGKRDNDPLFWGDELEYMVVDFDDKERNSMLDVCHDKILTELNMEDSSLCEANDVSFHPEYGRYMLEATPASPYLNYVGSYVEVNMQKRRAIAEYKLSEYARQDSKNNLHVGSRSVPLTLTVFPRMGCPDFINIKDPWNHKNAASRSLFLPDEVINRHVRFPNLTASIRTRRGEKVCMNVPMYKDIATPETDDSIYDRDWFLPEDKEAKLASKPGFIYMDSMGFGMGCSCLQVTFQAPNINKARYLYDALVNFAPIMLAFSAAAPAFKGWLADQDVRWNVISGAVDDRTPKERGVAPLLPKYNKNGFGGIAKDVQDKVLEIPKSRYSSVDLFLGGSKFFNRTYNDTNVPINEKVLGRLLENDKAPLDYDLAKHFAHLYIRDPVSTFEELLNQDNKTSSNHFENIQSTNWQTLRFKPPTQQATPDKKDSPGWRVEFRPFEVQLLDFENAAYSVLIYLIVDSILTFSDNINAYIHMSKVWENMKIAHHRDAILFEKFHWKKSFRNDTDVETEDYSISEIFHNPENGIFPQFVTPILCQKGFVTKDWKELKHSSKHERLYYYLKLISDRASGELPTTAKFFRNFVLQHPDYKHDSKISKSINYDLLSTCDRLTHLDDSKGELTSFLGAEIAEYVKKNKPSIESKC
SIO_010081: YJL101C
subclass of: SO_0000673
so part of: YJL101C
location: complement(234320..236356)
location: region:234320-236356:-1
so has part: feature:234320-236356:-1:exon

NP_012434.1
type: Protein
SIO_000068: ncbiprotein

S000003637
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:234320-236356:-1:exon

YJL100W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: LSB6
locus tag: YJL100W
so part of: sequence
location: <237263..>239086
location: region:237263-239086:1
so has part: feature:237263-239086:1:exon
subclass of: SO_0000010

853345
type: Gene
SIO_000068: ncbigene

position:237263:1
position: 237263
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:239086:1
position: 239086
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:237263-239086:1:exon

YJL100W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: LSB6
locus tag: YJL100W
product: 1-phosphatidylinositol 4-kinase LSB6
transcript id: NM_001181533.1
SIO_010081: YJL100W
subclass of: SO_0000673
so part of: YJL100W
location: <237263..>239086
location: region:237263-239086:1
so has part: feature:237263-239086:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:237263-239086:1:exon

YJL100W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: LSB6
locus tag: YJL100W
EC number: 2.7.1.67
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:12361950|PMID:12523934|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0004430 1-phosphatidylinositol 4-kinase activity [PMID:12361950|PMID:12523934]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:12361950|PMID:12523934]
experiment: EXISTENCE:direct assay:GO:0046854 phosphatidylinositol phosphate biosynthetic process [PMID:12523934|PMID:12361950]
experiment: EXISTENCE:mutant phenotype:GO:0004430 1-phosphatidylinositol 4-kinase activity [PMID:12361950]
experiment: EXISTENCE:mutant phenotype:GO:0046854 phosphatidylinositol phosphate biosynthetic process [PMID:12361950]
note: Type II phosphatidylinositol 4-kinase; binds Las17p, a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization
codon start: 1
product: 1-phosphatidylinositol 4-kinase LSB6
translation: MSNEAYQHDHTVNPHQKIVVNSYDWLQFRDEQDHCKSKNPITHASPGVGSNAQNSDIAEAPQVFHPSYQSLVNVPSESPRPDQTSGSNPAVGLLHNAEDKASGQEEEGSQYEIQYSVFRPLHAYPTKGLAYEQLRRKEEQEQRENFNHLVSDCIEAVETFGRELERIQTGSSGSYFVYGTRADESVPVGVFKPKDEEPYGPFSPKWTKWAHRTFFPCLFGRSCLIPNLGYICESAASLLDRRLETHLVPYTDTASIESFNFYDNRKKWVLGYNLQKKKQKKLGSFQLFLKEYINADEFFHKYPLPGMYSDVKHSFHRKSSGEDINHKPETTRNLTDETEPSKQINSSPISTESEENSKFEWTESSLSQFRLELEKLIILDYIMRNTDRGLDNWMVKLIKLSNNKWRLKLAAIDNGLSFPWKHPDEWRLYPYGWLYLPLQLLAKPFSEQMRSHFLPILTSTNWWEESYQEFLALFSRDQDFNVRMWKKQWAVLKGQAFNVVETLKDPRQGPLELVRRTRCQVIDEKMQVPCCPPPVSIFKNAIDEPIGSYSTSPMVLPSTPSTIPFHAHNQSNSNPVYYDSTLHPFANKTVIAERLQIVNSTPVFTWC
SIO_010081: YJL100W
subclass of: SO_0000673
so part of: YJL100W
location: 237263..239086
location: region:237263-239086:1
so has part: feature:237263-239086:1:exon

NP_012435.1
type: Protein
SIO_000068: ncbiprotein

S000003636
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:237263-239086:1:exon

YJL099W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CSD3
gene: CHS6
locus tag: YJL099W
gene synonym: CSD3
so part of: sequence
location: <239414..>241654
location: region:239414-241654:1
so has part: feature:239414-241654:1:exon
subclass of: SO_0000010

853346
type: Gene
SIO_000068: ncbigene

position:239414:1
position: 239414
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:241654:1
position: 241654
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:239414-241654:1:exon

YJL099W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CSD3
gene: CHS6
locus tag: YJL099W
gene synonym: CSD3
product: Chs6p
transcript id: NM_001181532.1
SIO_010081: YJL099W
subclass of: SO_0000673
so part of: YJL099W
location: <239414..>241654
location: region:239414-241654:1
so has part: feature:239414-241654:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:239414-241654:1:exon

YJL099W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CSD3
gene: CHS6
locus tag: YJL099W
gene synonym: CSD3
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0030136 clathrin-coated vesicle [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0030140 trans-Golgi network transport vesicle [PMID:16498409]
experiment: EXISTENCE:direct assay:GO:0034044 exomer complex [PMID:17000877|PMID:23000721]
experiment: EXISTENCE:genetic interaction:GO:0006893 Golgi to plasma membrane transport [PMID:16498409]
experiment: EXISTENCE:mutant phenotype:GO:0006893 Golgi to plasma membrane transport [PMID:11879634|PMID:9614194]
experiment: EXISTENCE:mutant phenotype:GO:0034221 fungal-type cell wall chitin biosynthetic process [PMID:9614194]
note: Member of the ChAPs (Chs5p-Arf1p-binding proteins) family; part of the exomer complex that mediates export of specific cargo proteins, including Chs3p, from the Golgi to the plasma membrane; primary component of the Chs5/6 complex that binds directly to membranes; CHS6 has a paralog, BCH2, that arose from the whole genome duplication
codon start: 1
product: Chs6p
translation: MNLFWPSETKKQNEIPGGDYTPGNSPSVQKGYQFLNRDIFKSCPRIMERQFGECLHNRTHLIKDLISSGNVGLGPIEIVHMSYLNKHEKEEFGEYFYVTGIEVSGPAMPVEFLEVLKSSKRISKNISNNIILTYCCFNFFSNLDIRIRYDADDTFQTTAIDCNKETTDLTMTEKMWEETFASSVIRAIITNTNPELKPPGLVECPFYVGKDTISSCKKIIELLCRFLPRSLNCGWDSTKSMQATIVNNYLMYSLKSFIAITPSLVDFTIDYLKGLTKKDPIHDIYYKTAMITILDHIETKELDMITILNETLDPLLSLLNDLPPRDADSARLMNCMSDLLNIQTNFLLNRGDYELALGVSNTSTELALDSFESWYNLARCHIKKEEYEKALFAINSMPRLRKNDGHLETMYSRFLTSNYYKKPLNGTREHYDLTAMEFTNLSGTLRNWKEDELKRQIFGRIAMINEKKIGYTKEIWDDIAIKLGPICGPQSVNLINYVSPQEVKNIKNINLIARNTIGKQLGWFSGKIYGLLMEIVNKIGWNGLLNIRTEAFMMETEFYQASNNIIDENGHIPMESRKKRFCEGWLDDLFLDLYQDLKLSKISLSNKDEKHSGLEWELLGLIMLRTWHWEDAVACLRTSIVARFDPVSCQQLLKIYLQPPKNIQEVTLLDTDTIISLLIKKISYDCRYYNYCQIFNLQLLEKLCNELGTHILRNKILLQPSIGDEIMVMIDAMLAWIADLDHTVQP
SIO_010081: YJL099W
subclass of: SO_0000673
so part of: YJL099W
location: 239414..241654
location: region:239414-241654:1
so has part: feature:239414-241654:1:exon

NP_012436.1
type: Protein
SIO_000068: ncbiprotein

S000003635
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:239414-241654:1:exon

YJL098W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SAP185
locus tag: YJL098W
so part of: sequence
location: <242082..>245258
location: region:242082-245258:1
so has part: feature:242082-245258:1:exon
subclass of: SO_0000010

853347
type: Gene
SIO_000068: ncbigene

position:242082:1
position: 242082
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:245258:1
position: 245258
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:242082-245258:1:exon

YJL098W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SAP185
locus tag: YJL098W
product: Sap185p
transcript id: NM_001181531.1
SIO_010081: YJL098W
subclass of: SO_0000673
so part of: YJL098W
location: <242082..>245258
location: region:242082-245258:1
so has part: feature:242082-245258:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:242082-245258:1:exon

YJL098W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SAP185
locus tag: YJL098W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:14576278]
experiment: EXISTENCE:direct assay:GO:1903766 positive regulation of potassium ion export across plasma membrane [PMID:15947196]
experiment: EXISTENCE:genetic interaction:GO:0002098 tRNA wobble uridine modification [PMID:18755837]
experiment: EXISTENCE:mutant phenotype:GO:0000082 G1/S transition of mitotic cell cycle [PMID:8649382]
experiment: EXISTENCE:mutant phenotype:GO:1903766 positive regulation of potassium ion export across plasma membrane [PMID:15947196]
note: Protein that forms a complex with the Sit4p protein phosphatase; required for Sit4p function; member of a family of similar proteins including Sap4p, Sap155p, and Sap190p; SAP185 has a paralog, SAP190, that arose from the whole genome duplication
codon start: 1
product: Sap185p
translation: MSGSFWKFGQDFGSQSPLAKLLNRAFIKIDDKPTSTEAGKIDSNSTDESLESNSFKSEDEEEEYELPNREEDYKAYKPNLSLLNDLLDDEELYTELMCSNFKLLVYLKYPEVLSKLIDYVRNSTILESNIDRVTSEDRDLVRGEDKDTTEDFENAKADKKNIDGTFEEKERTRSGEEEELENEENDSASEDTRVTLPHELEEHDDTRRARIAAEILSADVWPISSALIENEGLLAKLWSILRLPSPLSIEASTYFMKINERLLDMNMDGIIEFILKKEHIVDDFLAHIDNPPLMDFLLKVISTDKPEISNGVIQLFKKQNLVPKLIHLLDPVFDSCTQSAAGDFLKALVTISGNCPNEITSSIGPNELTRQLVSPNMMKQLMDIMLKGGNSLNNGVGIIIELIRKNNSDYDTIQTNYTTIESHPPTDRDPIYLGYLVKMFSEHMADFNKILTEKKIPLLQTSYGTIEPLGFERFKICELIAELLHCSNMTLLNEPSAYDIVRERDAERERIFNSQNYVDSNDRSELKENEDDNTGDADDEVEDDTNQVESANTSIDGEEVIDKLNSLQIETNKVNQNMNNEEQHSLMPDFNNGDFKDEEDENPFEPQYSDVILDSSDIEKNFRVSPNVGDQLKISLQDTRVIDTMLEMFFHFQWNNFLHNVVYDVVQQIFNGPLKIGYNRFLLDDLLINIRLTDMIINGNNECIEYEKGHDTRLGYMGHLTLIAEEVTKFTAYIEEMNITFENTEVMSSLFESKWIAYTEDVLEDLKEKYNAILGDIAEEGDMLQDEEEDAVYDKGERTMGTVDDYINDIMQMDNVRCQEEEEDEGEGYVSFDEDEPQEYRNGDSVRSKESNSSEGKRDQEQLYYEYVNEDGTKTRLNFNPDSDATEQVPGEVNRDHKIPLKLKRSFTDACKSETIPNNTVNAKEESVFQFSNELSDGWESSPSNSIPKRASPSKNGMNSPMFQHQFELHSPTDEFGGHKDEILSAEGHDYDIDEYDELSDDSDEEYDNCEDEDSLDYADSAAYALCRSKSKDKISWDEEEQARLMGVVKFNSEHYRD
SIO_010081: YJL098W
subclass of: SO_0000673
so part of: YJL098W
location: 242082..245258
location: region:242082-245258:1
so has part: feature:242082-245258:1:exon

NP_012437.1
type: Protein
SIO_000068: ncbiprotein

S000003634
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:242082-245258:1:exon

YJL097W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PHS1
locus tag: YJL097W
so part of: sequence
location: <245591..>246244
location: region:245591-246244:1
so has part: feature:245591-246244:1:exon
subclass of: SO_0000010

853348
type: Gene
SIO_000068: ncbigene

position:245591:1
position: 245591
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:246244:1
position: 246244
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:245591-246244:1:exon

YJL097W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PHS1
locus tag: YJL097W
product: enoyl-CoA hydratase PHS1
transcript id: NM_001181530.1
SIO_010081: YJL097W
subclass of: SO_0000673
so part of: YJL097W
location: <245591..>246244
location: region:245591-246244:1
so has part: feature:245591-246244:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:245591-246244:1:exon

YJL097W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PHS1
locus tag: YJL097W
EC number: 4.2.1.134
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:23708375|PMID:14562095|PMID:14690591]
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:14690591]
experiment: EXISTENCE:direct assay:GO:0004300 enoyl-CoA hydratase activity [PMID:18272525]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:14562095|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:18272525]
experiment: EXISTENCE:direct assay:GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network [PMID:14690591]
experiment: EXISTENCE:mutant phenotype:GO:0007034 vacuolar transport [PMID:16943325]
experiment: EXISTENCE:mutant phenotype:GO:0018812 3-hydroxyacyl-CoA dehydratase activity [PMID:23416297]
experiment: EXISTENCE:mutant phenotype:GO:0030148 sphingolipid biosynthetic process [PMID:18272525]
experiment: EXISTENCE:mutant phenotype:GO:0030497 fatty acid elongation [PMID:23416297]
note: Essential 3-hydroxyacyl-CoA dehydratase of the ER membrane; involved in elongation of very long-chain fatty acids; evolutionarily conserved, similar to mammalian PTPLA and PTPLB; involved in sphingolipid biosynthesis and protein trafficking
codon start: 1
product: enoyl-CoA hydratase PHS1
translation: MSKKLASPLSFLPLYNLLSAVGWSYLLYLVISLYPKVGQPAFFYQTKNVATLVQCGAIIEIINSFLGVVRSPLLTTVAQVSSRLLVVLGIFQLLPNTSGVQSVVYISLLLAWSITEIVRYLYYFFMLVFKNGAPKILILLRYNLFWILYPTGVASELRIIYCALNAAESQYSLLYKRILIAAMLAYIPGFPMLFLHMVAQRKKVMKSLRSSFGKKLI
SIO_010081: YJL097W
subclass of: SO_0000673
so part of: YJL097W
location: 245591..246244
location: region:245591-246244:1
so has part: feature:245591-246244:1:exon

NP_012438.1
type: Protein
SIO_000068: ncbiprotein

S000003633
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:245591-246244:1:exon

YJL096W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: bL21m
gene: MRPL49
locus tag: YJL096W
gene synonym: bL21m
so part of: sequence
location: <246490..>246975
location: region:246490-246975:1
so has part: feature:246490-246975:1:exon
subclass of: SO_0000010

853349
type: Gene
SIO_000068: ncbigene

position:246490:1
position: 246490
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:246975:1
position: 246975
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:246490-246975:1:exon

YJL096W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: bL21m
gene: MRPL49
locus tag: YJL096W
gene synonym: bL21m
product: mitochondrial 54S ribosomal protein YmL49
transcript id: NM_001181529.1
SIO_010081: YJL096W
subclass of: SO_0000673
so part of: YJL096W
location: <246490..>246975
location: region:246490-246975:1
so has part: feature:246490-246975:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:246490-246975:1:exon

YJL096W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: bL21m
gene: MRPL49
locus tag: YJL096W
gene synonym: bL21m
experiment: EXISTENCE:curator inference:GO:0032543 mitochondrial translation [PMID:12392552|PMID:9151978]
experiment: EXISTENCE:direct assay:GO:0003735 structural constituent of ribosome [PMID:12392552|PMID:9151978]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005762 mitochondrial large ribosomal subunit [PMID:12392552|PMID:9151978]
note: Mitochondrial ribosomal protein of the large subunit
codon start: 1
product: mitochondrial 54S ribosomal protein YmL49
translation: MLQLKFIWPVARITPIYRPFTSHPFRNLATSSSISSTKAKTTKTDTTPLKLSNELYAIFKIHNRPYLVTEGDRVILPFKLKQAEVGDILNMTDVTTLGSRNYKLVGHPINTSLYTLKATVVGKTKRAFQTREVTKRRNRRVRHAKSKGDLTILRISELSMN
SIO_010081: YJL096W
subclass of: SO_0000673
so part of: YJL096W
location: 246490..246975
location: region:246490-246975:1
so has part: feature:246490-246975:1:exon

NP_012439.2
type: Protein
SIO_000068: ncbiprotein

S000003632
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:246490-246975:1:exon

misc_feature
type: Miscellaneous Feature
subclass of: SO_0000001
RO_0002162: 559292
note: ETC3; Chromosome-organizing-clamp; tethers chromosomal regions to the nuclear periphery; binds TFIIIC transcription factor but does not recruit RNA Polymerase III; located between MRPL49 and BCK1
so part of: sequence
location: 247060..247082
location: region:247060-247082:1
so has part: feature:247060-247082:1:region

S000077074
type: SGD
SIO_000068: sgd

position:247060:1
position: 247060
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:247082:1
position: 247082
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:247060-247082:1:region

YJL095W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LAS3
alternative label: SAP3
alternative label: SLK1
alternative label: SSP31
gene: BCK1
locus tag: YJL095W
gene synonym: LAS3; SAP3; SLK1; SSP31
so part of: sequence
location: <247255..>251691
location: region:247255-251691:1
so has part: feature:247255-251691:1:exon
subclass of: SO_0000010

853350
type: Gene
SIO_000068: ncbigene

position:247255:1
position: 247255
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:251691:1
position: 251691
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:247255-251691:1:exon

YJL095W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LAS3
alternative label: SAP3
alternative label: SLK1
alternative label: SSP31
gene: BCK1
locus tag: YJL095W
gene synonym: LAS3; SAP3; SLK1; SSP31
product: mitogen-activated protein kinase kinase kinase BCK1
transcript id: NM_001181528.1
SIO_010081: YJL095W
subclass of: SO_0000673
so part of: YJL095W
location: <247255..>251691
location: region:247255-251691:1
so has part: feature:247255-251691:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:247255-251691:1:exon

YJL095W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LAS3
alternative label: SAP3
alternative label: SLK1
alternative label: SSP31
gene: BCK1
locus tag: YJL095W
gene synonym: LAS3; SAP3; SLK1; SSP31
EC number: 2.7.11.1
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:16319894]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:19053807]
experiment: EXISTENCE:genetic interaction:GO:0000196 cell wall integrity MAPK cascade [PMID:1729597|PMID:8386320]
experiment: EXISTENCE:genetic interaction:GO:0060237 regulation of fungal-type cell wall organization [PMID:1729597]
experiment: EXISTENCE:mutant phenotype:GO:0004709 MAP kinase kinase kinase activity [PMID:11283616]
experiment: EXISTENCE:mutant phenotype:GO:0010447 response to acidic pH [PMID:16087742]
experiment: EXISTENCE:mutant phenotype:GO:0030010 establishment of cell polarity [PMID:1545797]
experiment: EXISTENCE:mutant phenotype:GO:0030242 autophagy of peroxisome [PMID:20385774]
experiment: EXISTENCE:mutant phenotype:GO:0030968 endoplasmic reticulum unfolded protein response [PMID:16380504]
experiment: EXISTENCE:mutant phenotype:GO:0035556 intracellular signal transduction [PMID:8190082]
experiment: EXISTENCE:mutant phenotype:GO:0060237 regulation of fungal-type cell wall organization [PMID:1729597]
note: MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase
codon start: 1
product: mitogen-activated protein kinase kinase kinase BCK1
translation: MPFLRKIAGTAHTHSRSDSNSSVKFGHQPTSSVASTKSSSKSPRATSRKSIYDDIRSQFPNLTPNSTSSQFYESTPVIEQSFNWTTDDHISAGTLENPTSFTNSSYKNDNGPSSLSDSRKSSGGNSVNSLSFDKLILSWDPTDPDEWTMHRVTSWFKFHDFPESWILFFKKHQLFGHRFIKLLAYDNFAVYEKYLPQTKTASYTRFQQLLKKTMTKNVTNSHIRQKSASKLKSSRSSSESIKSKLKNSKSQEDISNSRSTSESALSPTKSGPSKTDEKNFLHSTSTHQKTKSASSLYRRSFISLRGSSSSNASSAKSPSNIKLSIPARPHSIIESNSTLTKSASPPASPSYPSIFRRHHKSSSSESSLLNSLFGSGIGEEAPTKPNPQGHSLSSENLAKGKSKHYETNVSSPLKQSSLPTSDDKGNLWNKFKRKSQIGVPSPNTVAYVTSQETPSLKSNSSTATLTVQTADVNIPSPSSSPPPIPKTANRSLEVISTEDTPKISSTTASFKETYPDCINPDKTVPVPVNNQKYSVKNFLLDQKFYPLKKTGLNDSENKYILVTKDNVSFVPLNLKSVAKLSSFKESALTKLGINHKNVTFHMTDFDCDIGAAIPDDTLEFLKKSLFLNTSGKIYIKDQMKLQQKPKPAPLTSENNVPLKSVKSKSSMRSGTSSLIASTDDVSIVTSSSDITSFDEHASGSGRRYPQTPSYYYDRVSNTNPTEELNYWNIKEVLSHEENAPKMVFKTSPKLELNLPDKGSKLNIPTPITENESKSSFQVLRKDEGTEIDFNHRRESPYTKPELAPKREAPKPPANTSPQRTLSTSKQNKPIRLVRASTKISRSKRSKPLPPQLLSSPIEASSSSPDSLTSSYTPASTHVLIPQPYKGANDVMRRLKTDQDSTSTSPSLKMKQKVNRSNSTVSTSNSIFYSPSPLLKRGNSKRVVSSTSAADIFEENDITFADAPPMFDSDDSDDDSSSSDDIIWSKKKTAPETNNENKKDEKSDNSSTHSDEIFYDSQTQDKMERKMTFRPSPEVVYQNLEKFFPRANLDKPITEGIASPTSPKSLDSLLSPKNVASSRTEPSTPSRPVPPDSSYEFIQDGLNGKNKPLNQAKTPKRTKTIRTIAHEASLARKNSVKLKRQNTKMWGTRMVEVTENHMVSINKAKNSKGEYKEFAWMKGEMIGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEKRPTANELLSHPFSEVNETFNFKSTRLAKFIKSNDKLNSSKLRITSQENKTE
SIO_010081: YJL095W
subclass of: SO_0000673
so part of: YJL095W
location: 247255..251691
location: region:247255-251691:1
so has part: feature:247255-251691:1:exon

NP_012440.1
type: Protein
SIO_000068: ncbiprotein

S000003631
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:247255-251691:1:exon

YJL094C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: KHA1
locus tag: YJL094C
so part of: sequence
location: complement(<251821..>254442)
location: region:251821-254442:-1
so has part: feature:251821-254442:-1:exon
subclass of: SO_0000010

853351
type: Gene
SIO_000068: ncbigene

position:251821:-1
position: 251821
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:254442:-1
position: 254442
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:251821-254442:-1:exon

YJL094C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: KHA1
locus tag: YJL094C
product: Kha1p
transcript id: NM_001181527.1
SIO_010081: YJL094C
subclass of: SO_0000673
so part of: YJL094C
location: complement(<251821..>254442)
location: region:251821-254442:-1
so has part: feature:251821-254442:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:251821-254442:-1:exon

YJL094C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: KHA1
locus tag: YJL094C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005794 Golgi apparatus [PMID:15926887]
experiment: EXISTENCE:mutant phenotype:GO:0015386 potassium:proton antiporter activity [PMID:9811642]
experiment: EXISTENCE:mutant phenotype:GO:0098662 inorganic cation transmembrane transport [PMID:9811642]
note: Putative K+/H+ antiporter; involved in intracellular cation homeostasis; promotes copper binding to Fet3p multicopper oxidase; localized to Golgi vesicles and detected in highly purified mitochondria in high-throughput studies
codon start: 1
product: Kha1p
translation: MANTVGGILSGVNPFHYNSSSPLTLFLFQACLILLVCNLIHIPFSMMRQPKVISEVISGVILGPTIFGQIPNYTNTIFPTSSIPGLNLVANLGIILFMFFLGLEVDIAFIKKHLKKALVIGIVTLAVPFGFGCLLAIPLFHTYANKTEGERHIKFSVFMVFIAVSISVTAFPVLCRILNELRLIKDRAGIVVLAAGIINDIMGWILLALSIILSSAEGSPVNTVYILLITFAWFLIYFFPLKYLLRWVLIRTHELDRSKPSPLATMCILFIMFISAYFTDIIGVHPIFGAFIAGLVVPRDDHYVVKLTERMEDIPNIVFIPIYFAVAGLNVDLTLLNEGRDWGYVFATIGIAIFTKIISGTLTAKLTGLFWREATAAGVLMSCKGIVEIVVLTVGLNAGIISRKIFGMFVLMALVSTFVTTPLTQLVYPDSYRDGVRKSLSTPAEDDGAADGLDSEGVDKTEINTQLNSLADVSKYRIGELTTVINTTEAISPSLKLLNYLSLGVSPKPKNNKHKNETSLSRMTTATDSTLKSNTFKIKKMVHIWSKSVDDVDTNLSVIDEKLTPFEGVGALRAIHLRLLTERTTDLLQSSSLYNDDPHFTANTDSLLQIFDIFSNLSKIPFSSEVIFSTMREKAANIATMKMDSTDLILLPLKGASYEYRGSPVFIDEKYANFDHIYSHLLGLNELSSTFFKSIFQSLKANFAVQISNTYGRLNADRFKRKRFNLLLPKPYLTQSDYLGLYLLLLICYRDGYNNDNASCSIFINSKNIDFAKDLSTAFAEHDWLNESTIKIVDIPFETKVPEEAIEKPSFIETVLDVGLSDTALADIEETTFIIGEDLPDESEPFSEEVRTVIFEGSNRRFDTLIVHHFSSE
SIO_010081: YJL094C
subclass of: SO_0000673
so part of: YJL094C
location: complement(251821..254442)
location: region:251821-254442:-1
so has part: feature:251821-254442:-1:exon

NP_012441.1
type: Protein
SIO_000068: ncbiprotein

S000003630
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:251821-254442:-1:exon

YJL093C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: DUK1
alternative label: YKC1
alternative label: YPK1
gene: TOK1
locus tag: YJL093C
gene synonym: DUK1; YKC1; YPK1
so part of: sequence
location: complement(<254737..>256812)
location: region:254737-256812:-1
so has part: feature:254737-256812:-1:exon
subclass of: SO_0000010

853352
type: Gene
SIO_000068: ncbigene

position:254737:-1
position: 254737
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:256812:-1
position: 256812
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:254737-256812:-1:exon

YJL093C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: DUK1
alternative label: YKC1
alternative label: YPK1
gene: TOK1
locus tag: YJL093C
gene synonym: DUK1; YKC1; YPK1
product: Tok1p
transcript id: NM_001181526.1
SIO_010081: YJL093C
subclass of: SO_0000673
so part of: YJL093C
location: complement(<254737..>256812)
location: region:254737-256812:-1
so has part: feature:254737-256812:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:254737-256812:-1:exon

YJL093C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: DUK1
alternative label: YKC1
alternative label: YPK1
gene: TOK1
locus tag: YJL093C
gene synonym: DUK1; YKC1; YPK1
experiment: EXISTENCE:direct assay:GO:0005267 potassium channel activity [PMID:7651518]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:7651518]
experiment: EXISTENCE:direct assay:GO:0030007 cellular potassium ion homeostasis [PMID:7651518]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0005249 voltage-gated potassium channel activity [PMID:16133265]
experiment: EXISTENCE:mutant phenotype:GO:0005267 potassium channel activity [PMID:7651518]
experiment: EXISTENCE:mutant phenotype:GO:0005886 plasma membrane [PMID:7651518]
experiment: EXISTENCE:mutant phenotype:GO:0030007 cellular potassium ion homeostasis [PMID:7651518]
note: Outward-rectifier potassium channel of the plasma membrane; has two pore domains in tandem, each of which forms a functional channel permeable to potassium; carboxy tail functions to prevent inner gate closures; target of K1 toxin
codon start: 1
product: Tok1p
translation: MTRFMNSFAKQTLGYGNMATVEQESSAQAVDSHSNNTPKQAKGVLAEELKDALRFRDERVSIINAEPSSTLFVFWFVVSCYFPVITACLGPVANTISIACVVEKWRSLKNNSVVTNPRSNDTDVLMNQVKTVFDPPGIFAVNIISLVLGFTSNIILMLHFSKKLTYLKSQLINITGWTIAGGMLLVDVIVCSLNDMPSIYSKTIGFWFACISSGLYLVCTIILTIHFIGYKLGKYPPTFNLLPNERSIMAYTVLLSLWLIWGAGMFSGLLHITYGNALYFCTVSLLTVGLGDILPKSVGAKIMVLIFSLSGVVLMGLIVFMTRSIIQKSSGPIFFFHRVEKGRSKSWKHYMDSSKNLSEREAFDLMKCIRQTASRKQHWFSLSVTIAIFMAFWLLGALVFKFAENWSYFNCIYFCFLCLLTIGYGDYAPRTGAGRAFFVIWALGAVPLMGAILSTVGDLLFDISTSLDIKIGESFNNKVKSIVFNGRQRALSFMVNTGEIFEESDTADGDLEENTTSSQSSQISEFNDNNSEENDSGVTSPPASLQESFSSLSKASSPEGILPLEYVSSAEYALQDSGTCNLRNLQELLKAVKKLHRICLADKDYTLSFSDWSYIHKLHLRNITDIEEYTRGPEFWISPDTPLKFPLNEPHFAFMMLFKNIEELVGNLVEDEELYKVISKRKFLGEHRKTL
SIO_010081: YJL093C
subclass of: SO_0000673
so part of: YJL093C
location: complement(254737..256812)
location: region:254737-256812:-1
so has part: feature:254737-256812:-1:exon

NP_012442.1
type: Protein
SIO_000068: ncbiprotein

S000003629
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:254737-256812:-1:exon

YJL092W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: HPR5
gene: SRS2
locus tag: YJL092W
gene synonym: HPR5
so part of: sequence
location: <257423..>260947
location: region:257423-260947:1
so has part: feature:257423-260947:1:exon
subclass of: SO_0000010

853353
type: Gene
SIO_000068: ncbigene

position:257423:1
position: 257423
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:260947:1
position: 260947
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:257423-260947:1:exon

YJL092W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: HPR5
gene: SRS2
locus tag: YJL092W
gene synonym: HPR5
product: DNA helicase SRS2
transcript id: NM_001181525.1
SIO_010081: YJL092W
subclass of: SO_0000673
so part of: YJL092W
location: <257423..>260947
location: region:257423-260947:1
so has part: feature:257423-260947:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:257423-260947:1:exon

YJL092W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: HPR5
gene: SRS2
locus tag: YJL092W
gene synonym: HPR5
EC number: 3.6.4.12
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:19506039]
experiment: EXISTENCE:direct assay:GO:0006303 double-strand break repair via nonhomologous end joining [PMID:10908335]
experiment: EXISTENCE:direct assay:GO:0008047 enzyme activator activity [PMID:25765656]
experiment: EXISTENCE:direct assay:GO:0032079 positive regulation of endodeoxyribonuclease activity [PMID:25765656]
experiment: EXISTENCE:direct assay:GO:0032508 DNA duplex unwinding [PMID:18440969]
experiment: EXISTENCE:direct assay:GO:0043138 3'-5' DNA helicase activity [PMID:8419328]
experiment: EXISTENCE:direct assay:GO:1990986 DNA recombinase disassembly [PMID:12748645|PMID:12748644]
experiment: EXISTENCE:direct assay:GO:2000042 negative regulation of double-strand break repair via homologous recombination [PMID:19595720]
experiment: EXISTENCE:genetic interaction:GO:0006281 DNA repair [PMID:7768432]
experiment: EXISTENCE:mutant phenotype:GO:0042262 DNA protection [PMID:31168653]
experiment: EXISTENCE:mutant phenotype:GO:0045910 negative regulation of DNA recombination [PMID:23770697]
experiment: EXISTENCE:mutant phenotype:GO:1990986 DNA recombinase disassembly [PMID:23770697]
experiment: EXISTENCE:physical interaction:GO:0005515 protein binding [PMID:31142613]
note: DNA helicase and DNA-dependent ATPase; role in DNA repair and checkpoint recovery, in the proper timing of commitment to meiotic recombination and the Meiosis I to II transition; blocks trinucleotide repeat expansion; affects genome stability; disassembles Rad51p nucleoprotein filaments during meiotic recombination; stimulates Mus81p-Mms4p endonuclease activity independent of catalytic activity; ATPase and ssDNA translocating motor activities inhibited by Dmc1p; functional homolog of human RTEL1
codon start: 1
product: DNA helicase SRS2
translation: MSSNNDLWLHLVSQLNTQQRAAALFDYTRGLQVIAGPGTGKTKVLTSRVAYLILHHHIHPRDIIVTTFTNKAANEMKERLQEMLRGAGVNISELLIGTFHSICLKILYRFGHLVDLQKDWRIIDEKEIDVILDDMIEKVPDQIRDYASSITRKVNLCMPSKNGDEWTIHPKLIKKQISKLKSNAILPEEYILDSNHDAALGYFYQIYQSELSKKNTLDFDDLLMYTFRLLTRVRVLSNIKHVLVDEFQDTNGIQLDLMFLFAKGNHHLSRGMTIVGDPDQSIYAFRNALAHNFLEMGRKCPIEYSTIILVENYRSSQKILNTSEILITQQNKGRQNRAPLRAQFDLDFPPVYMNFPAYFLEAPSLVRELLYLKALPNLFTFNDFAILVRQRRQIKRIESALIEHRIPYKIIRGHSFWDSKETRAMLNLLKLIFSPNDKHAILASLLYPARGLGPATGEKIKNALDTLATDVSCFQILKDISSKKIMLDIPTKGRSVIADFISMIENCQLLLQSTLLGGLSDLFDKLYELSGLKYEYLYKDGKKKNDQLEKSEPNLLNARHKNIELLKNYFLALLSKSESSDKEKNEAIKAATDEAEPIENKVITPKEYLRNFFNSLSLHSDAAEEEESESNKDAKIKREKNGFVTISTIHGAKGLEWPVVFIPGCEEGIIPCVFNDDKKDESEEDEEEDQENSKKDASPKKTRVLSVEDSIDEERRMFFVAQTRAKYLLYLSNTVTVEDVDRPRIASRFLTTDLIKAMSDSQKLFESTNSIKKLYRILNKKPPAEDDKLFSLDQLRKDYNQFIENRRERMIWQGIQMNDVYGIQLSRNKLLGSVSDFTSAADQLRLETQNSIFPQKKLIEKSRPSKINGNYAPKSRVKSPEKRYAPETTSFHSPTKKKVYAPQYVSTTNVPSRQEFHSSTGKNIPFLRREDRSITDISPRSSTRSLKGASPNKTSHMSDDLMRPSPTRKDKVTRNIHFATAGTFRIETQSNVDELHPPEYSNKSGQSLTSSEFSGFSSACSNSDQPTNLIEDINNELDLSDEELLNDISIERRRELLGSKKTKKIKPKTRNRKSKRGDKVKVEEVIDLKSEFEEDDSRNTTAAELLHNPDDTTVDNRPIISNAKFLADAAMKKTQKFSKKVKNEPASSQMDIFSQLSRAKKKSKLNNGEIIVID
SIO_010081: YJL092W
subclass of: SO_0000673
so part of: YJL092W
location: 257423..260947
location: region:257423-260947:1
so has part: feature:257423-260947:1:exon

NP_012443.1
type: Protein
SIO_000068: ncbiprotein

S000003628
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:257423-260947:1:exon

YJL091C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GWT1
locus tag: YJL091C
so part of: sequence
location: complement(<261080..>262552)
location: region:261080-262552:-1
so has part: feature:261080-262552:-1:exon
subclass of: SO_0000010

853354
type: Gene
SIO_000068: ncbigene

position:261080:-1
position: 261080
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:262552:-1
position: 262552
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:261080-262552:-1:exon

YJL091C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GWT1
locus tag: YJL091C
product: glucosaminyl-phosphotidylinositol O-acyltransferase
transcript id: NM_001181524.1
SIO_010081: YJL091C
subclass of: SO_0000673
so part of: YJL091C
location: complement(<261080..>262552)
location: region:261080-262552:-1
so has part: feature:261080-262552:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:261080-262552:-1:exon

YJL091C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GWT1
locus tag: YJL091C
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0006506 GPI anchor biosynthetic process [PMID:12714589]
experiment: EXISTENCE:direct assay:GO:0016020 membrane [PMID:21367863]
experiment: EXISTENCE:direct assay:GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network [PMID:14690591]
experiment: EXISTENCE:genetic interaction:GO:0032216 glucosaminyl-phosphatidylinositol O-acyltransferase activity [PMID:14517336]
experiment: EXISTENCE:mutant phenotype:GO:0032216 glucosaminyl-phosphatidylinositol O-acyltransferase activity [PMID:16361252]
note: Protein involved in the inositol acylation of GlcN-PI; the inositol acylation of glucosaminyl phosphatidylinositol (GlcN-PI) forms glucosaminyl(acyl)phosphatidylinositol (GlcN(acyl)PI), an intermediate in the biosynthesis of glycosylphosphatidylinositol (GPI) anchors
codon start: 1
product: glucosaminyl-phosphotidylinositol O-acyltransferase
translation: MSTLKQRKEDFVTGLNGGSITEINAVTSIALVTYISWNLLKNSNLMPPGISSVQYIIDFALNWVALLLSITIYASEPYLLNTLILLPCLLAFIYGKFTSSSKPSNPIYNKKKMITQRFQLEKKPYITAYRGGMLILTAIAILAVDFPIFPRRFAKVETWGTSLMDLGVGSFVFSNGIVSSRALLKNLSLKSKPSFLKNAFNALKSGGTLLFLGLLRLFFVKNLEYQEHVTEYGVHWNFFITLSLLPLVLTFIDPVTRMVPRCSIAIFISCIYEWLLLKDDRTLNFLILADRNCFFSANREGIFSFLGYCSIFLWGQNTGFYLLGNKPTLNNLYKPSTQDVVAASKKSSTWDYWTSVTPLSGLCIWSTIFLVISQLVFQYHPYSVSRRFANLPYTLWVITYNLLFLTGYCLTDKIFGNSSEYYKVAECLESINSNGLFLFLLANVSTGLVNMSMVTIDSSPLKSFLVLLAYCSFIAVISVFLYRKRIFIKL
SIO_010081: YJL091C
subclass of: SO_0000673
so part of: YJL091C
location: complement(261080..262552)
location: region:261080-262552:-1
so has part: feature:261080-262552:-1:exon

NP_012444.2
type: Protein
SIO_000068: ncbiprotein

S000003627
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:261080-262552:-1:exon

YJL090C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: DPB11
locus tag: YJL090C
so part of: sequence
location: complement(<262757..>265051)
location: region:262757-265051:-1
so has part: feature:262757-265051:-1:exon
subclass of: SO_0000010

853355
type: Gene
SIO_000068: ncbigene

position:262757:-1
position: 262757
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:265051:-1
position: 265051
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:262757-265051:-1:exon

YJL090C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: DPB11
locus tag: YJL090C
product: protein kinase activating protein DPB11
transcript id: NM_001181523.1
SIO_010081: YJL090C
subclass of: SO_0000673
so part of: YJL090C
location: complement(<262757..>265051)
location: region:262757-265051:-1
so has part: feature:262757-265051:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:262757-265051:-1:exon

YJL090C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: DPB11
locus tag: YJL090C
experiment: EXISTENCE:direct assay:GO:0000725 recombinational repair [PMID:16840526]
experiment: EXISTENCE:direct assay:GO:0001934 positive regulation of protein phosphorylation [PMID:18842580|PMID:18922789]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005657 replication fork [PMID:10733584]
experiment: EXISTENCE:direct assay:GO:0030295 protein kinase activator activity [PMID:18922789]
experiment: EXISTENCE:direct assay:GO:0070182 DNA polymerase binding [PMID:10733584]
experiment: EXISTENCE:genetic interaction:GO:0000725 recombinational repair [PMID:16840526]
experiment: EXISTENCE:genetic interaction:GO:0007095 mitotic G2 DNA damage checkpoint signaling [PMID:18541674]
experiment: EXISTENCE:mutant phenotype:GO:0000076 DNA replication checkpoint signaling [PMID:10097122]
experiment: EXISTENCE:mutant phenotype:GO:0000727 double-strand break repair via break-induced replication [PMID:20516198]
experiment: EXISTENCE:mutant phenotype:GO:0006270 DNA replication initiation [PMID:10733584|PMID:23629628]
experiment: EXISTENCE:mutant phenotype:GO:0007533 mating type switching [PMID:21130053]
experiment: EXISTENCE:mutant phenotype:GO:0031261 DNA replication preinitiation complex [PMID:17167415]
experiment: EXISTENCE:mutant phenotype:GO:1902597 positive regulation of DNA replication origin binding [PMID:10733584]
note: DNA replication initiation protein; loads DNA pol epsilon onto pre-replication complexes at origins; checkpoint sensor recruited to stalled replication forks by the checkpoint clamp complex where it activates Mec1p; along with Rfa1p, binds to ultrafine anaphase bridges in mitotic cells and prevents accumulation of chromatin bridges by stimulating the Mec1p kinase and suppressing homologous recombination; ortholog of human TopBP1; forms nuclear foci upon DNA replication stress
codon start: 1
product: protein kinase activating protein DPB11
translation: MKPFQGITFCPTAINNEILAKKISKKIIKLGGIFSKDLTRQVNVLVVGSTTNTNKFKFAVKHRFDIIFIDIQAIDDIYQLWLSGENILPDSNTATMTGSTYEMLKILYRRFSFKYLHNFNIFIGRITDTNITSIDSLVRSIKKLGCSSYNYQNFVIKDTSSHNDDDDQGQNGQISIFVTDTLLGARVNAAIEQNIPIVHFKWILDCQKRSALLPYDPYYLLPNIKDLPYDSIGSNSCDCWDKINTTFPTNIDAQSSLQRQQSSSTLTPSLPKTSSLLNKFKPKGEKIWDKAMSLQQHSKTNFSVLGQSPLSINNKQEDLSDNSTLIFKNCAFIIHHIFPGNHRSILTKIVVQNGGKIETSYLSGIYDHSYYIIPSNKALDSFNDLPEIIDDNDGIVTEFFIERCLYYQKLLHPIDLWSKPFLSTIEFQVSSSSKLLHHEFSSSPFLNVTITGFSGVELLHLTKVLNLLKPMGINYVEYLNKSTDILLINLAALPSIPKTHPLWSNEFSDLFTQFCINNNNDDPGDNNRKDFQNNSILRNSMKRKIEYIKKFHSIPVVTPAFIFKLLSAASGENNEIFLNNIKWCIICPRGHKDDFKCKIKKPYYTSISSEKKYQNNDPKIDKTILLKRNNSSLSEHSMKDTKNELLQKIRETDSGRKKRSVSSSIMDVSSERQMPDTKRIKLESLPKNFVPKQIKRTTSWGTIMSENVPTEQPTAISNPEEIPRTEEVSHTQVTYGSIQDKKRTASLEKPMRRQTRNQTKELDS
SIO_010081: YJL090C
subclass of: SO_0000673
so part of: YJL090C
location: complement(262757..265051)
location: region:262757-265051:-1
so has part: feature:262757-265051:-1:exon

NP_012445.1
type: Protein
SIO_000068: ncbiprotein

S000003626
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:262757-265051:-1:exon

YJL089W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SIP4
locus tag: YJL089W
so part of: sequence
location: <265926..>268415
location: region:265926-268415:1
so has part: feature:265926-268415:1:exon
subclass of: SO_0000010

853356
type: Gene
SIO_000068: ncbigene

position:265926:1
position: 265926
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:268415:1
position: 268415
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:265926-268415:1:exon

YJL089W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SIP4
locus tag: YJL089W
product: Sip4p
transcript id: NM_001181522.1
SIO_010081: YJL089W
subclass of: SO_0000673
so part of: YJL089W
location: <265926..>268415
location: region:265926-268415:1
so has part: feature:265926-268415:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:265926-268415:1:exon

YJL089W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SIP4
locus tag: YJL089W
experiment: EXISTENCE:direct assay:GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding [PMID:11405098|PMID:14685767|PMID:9843506]
experiment: EXISTENCE:direct assay:GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific [PMID:14685767]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:11331606|PMID:9843506]
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:19111667]
experiment: EXISTENCE:genetic interaction:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:25123508]
experiment: EXISTENCE:genetic interaction:GO:0061414 positive regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source [PMID:25123508|PMID:9843506]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:9843506]
experiment: EXISTENCE:mutant phenotype:GO:0061414 positive regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source [PMID:9843506]
experiment: EXISTENCE:mutant phenotype:GO:2000218 negative regulation of invasive growth in response to glucose limitation [PMID:11095711]
experiment: EXISTENCE:physical interaction:GO:0045722 positive regulation of gluconeogenesis [PMID:9843506]
note: C6 zinc cluster transcriptional activator; binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated by Snf1p protein kinase; localized to the nucleus
codon start: 1
product: Sip4p
translation: MAKRKYGRSYSLDDTDSCSNKVLIVPTGQSSSNAITDFSVRKAHACDRCRLKKIKCDGLKPNCSNCAKIDFPCKTSDKLSRRGLPKGYTELLEKEVVRLTNMNASSSANANSNLPFINDTFYCFDNYNTQSENQRFLGHLTWNILTNTFPTQKAVVFTDDRNNIDLQLQLLTNFLNLNGDFNHLPNFLLLKYDYNLQFLKNLLSVIIKDFFKRQNSLLLLLYPTNLWKNLLLDKINSTAMTGEPITLLALLYIIQFTWSCFDDFKLFKVTKLIVSLTTNSKLDLKVLQLVNLSIFYFMGASVDSCKSKSSLTEHSNVNSVIWTNDLLNLNFTNILNMGLYINPKNLIPISGNNNNNKSNEEDDRIVTFWCFQFLSSWWSLIQGLPKSNFLTEEFQPKSISVLEIPRLKPFEILLNFIIYSLDGCNLLNISSLNVSDPNFQFFQNELESFKKNLLLWNLYHNLSDHDNFRFLTSSSNKKLTTNLLLKNLTGLNHKLNQPDFVEIQLTLFYLSLKLMTLKEGDQDLKKEDISLEILSLYFLILTDDSNNDDNQQLQPQQLNLYHFTPFNSIDIIDLCLNNLNNWSLSLKYESGQNQPHSSKIKFEKFQNFLNHWCPIWYYDEFSTNPFLQILKINFKLLPFETIHYSQEEQRLLISLNKLRYLDAVSSFNSSSVKSNFASKVNTQLNLLQHSSSNSNFLDASPYDFNKIFMNNFENYDYETDEGYAEDDDEEDSDSDNSLPLEIPFKKSKNKCKNRNKELSQRLSLFENRDSNSVDFNTDTNLNLNPDSPSVTSSKKKYLDHIILDNRDIVSNHDSSKQKFKIQNILNSTF
SIO_010081: YJL089W
subclass of: SO_0000673
so part of: YJL089W
location: 265926..268415
location: region:265926-268415:1
so has part: feature:265926-268415:1:exon

NP_012446.1
type: Protein
SIO_000068: ncbiprotein

S000003625
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:265926-268415:1:exon

YJL088W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ARG3
locus tag: YJL088W
so part of: sequence
location: <268799..>269815
location: region:268799-269815:1
so has part: feature:268799-269815:1:exon
subclass of: SO_0000010

853357
type: Gene
SIO_000068: ncbigene

position:268799:1
position: 268799
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:269815:1
position: 269815
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:268799-269815:1:exon

YJL088W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ARG3
locus tag: YJL088W
product: ornithine carbamoyltransferase
transcript id: NM_001181521.1
SIO_010081: YJL088W
subclass of: SO_0000673
so part of: YJL088W
location: <268799..>269815
location: region:268799-269815:1
so has part: feature:268799-269815:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:268799-269815:1:exon

YJL088W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ARG3
locus tag: YJL088W
EC number: 2.1.3.3
experiment: EXISTENCE:direct assay:GO:0004585 ornithine carbamoyltransferase activity [PMID:7029528]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:205532]
experiment: EXISTENCE:mutant phenotype:GO:0006526 arginine biosynthetic process [PMID:2897249]
note: Ornithine carbamoyltransferase; also known as carbamoylphosphate:L-ornithine carbamoyltransferase; catalyzes the biosynthesis of the arginine precursor citrulline
codon start: 1
product: ornithine carbamoyltransferase
translation: MSTTASTPSSLRHLISIKDLSDEEFRILVQRAQHFKNVFKANKTNDFQSNHLKLLGRTIALIFTKRSTRTRISTEGAATFFGAQPMFLGKEDIQLGVNESFYDTTKVVSSMVSCIFARVNKHEDILAFCKDSSVPIINSLCDKFHPLQAICDLLTIIENFNISLDEVNKGINSKLKMAWIGDANNVINDMCIACLKFGISVSISTPPGIEMDSDIVDEAKKVAERNGATFELTHDSLKASTNANILVTDTFVSMGEEFAKQAKLKQFKGFQINQELVSVADPNYKFMHCLPRHQEEVSDDVFYGEHSIVFEEAENRLYAAMSAIDIFVNNKGNFKDLK
SIO_010081: YJL088W
subclass of: SO_0000673
so part of: YJL088W
location: 268799..269815
location: region:268799-269815:1
so has part: feature:268799-269815:1:exon

NP_012447.1
type: Protein
SIO_000068: ncbiprotein

S000003624
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:268799-269815:1:exon

YJL087C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LIG1
alternative label: RLG1
gene: TRL1
locus tag: YJL087C
gene synonym: LIG1; RLG1
so part of: sequence
location: complement(<270002..>272485)
location: region:270002-272485:-1
so has part: feature:270002-272485:-1:exon
subclass of: SO_0000010

853358
type: Gene
SIO_000068: ncbigene

position:270002:-1
position: 270002
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:272485:-1
position: 272485
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:270002-272485:-1:exon

YJL087C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LIG1
alternative label: RLG1
gene: TRL1
locus tag: YJL087C
gene synonym: LIG1; RLG1
product: tRNA ligase
transcript id: NM_001181520.1
SIO_010081: YJL087C
subclass of: SO_0000673
so part of: YJL087C
location: complement(<270002..>272485)
location: region:270002-272485:-1
so has part: feature:270002-272485:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:270002-272485:-1:exon

YJL087C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LIG1
alternative label: RLG1
gene: TRL1
locus tag: YJL087C
gene synonym: LIG1; RLG1
EC number: 6.5.1.3
experiment: EXISTENCE:direct assay:GO:0003972 RNA ligase (ATP) activity [PMID:3277966|PMID:3512545]
experiment: EXISTENCE:direct assay:GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity [PMID:6297798]
experiment: EXISTENCE:direct assay:GO:0005637 nuclear inner membrane [PMID:3312232]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:20844078]
experiment: EXISTENCE:direct assay:GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation [PMID:2207062]
experiment: EXISTENCE:direct assay:GO:0051730 GTP-dependent polyribonucleotide 5'-hydroxyl-kinase activity [PMID:8428918]
experiment: EXISTENCE:mutant phenotype:GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation [PMID:1537841]
experiment: EXISTENCE:mutant phenotype:GO:0032056 positive regulation of translation in response to stress [PMID:20844078]
experiment: EXISTENCE:mutant phenotype:GO:0036498 IRE1-mediated unfolded protein response [PMID:8898194]
experiment: EXISTENCE:mutant phenotype:GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay [PMID:31913314]
experiment: EXISTENCE:mutant phenotype:GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [PMID:30874502]
note: tRNA ligase; required for tRNA splicing and for both splicing and translation of HAC1 mRNA in the UPR; has phosphodiesterase, polynucleotide kinase, and ligase activities; involved in turnover of tRNA introns; localized at the inner nuclear envelope and cytoplasm
codon start: 1
product: tRNA ligase
translation: MPSPYDGKRTVTQLVNELEKAEKLSGRGRAYRRVCDLSHSNKKVISWKFNEWDYGKNTITLPCNARGLFISDDTTNPVIVARGYDKFFNVGEVNFTKWNWIEENCTGPYDVTIKANGCIIFISGLEDGTLVVCSKHSTGPRADVDRNHAEAGEKQLLRQLAAMNINRSDFARMLYTHNVTAVAEYCDDSFEEHILEYPLEKAGLYLHGVNVNKAEFETWDMKDVSQMASKYGFRCVQCITSNTLEDLKKFLDNCSATGSFEGQEIEGFVIRCHLKSTEKPFFFKYKFEEPYLMYRQWREVTKDYISNKSRVFKFRKHKFITNKYLDFAIPILESSPKICENYLKGFGVIELRNKFLQSYGMSGLEILNHEKVAELELKNAIDYDKVDERTKFLIFPISVIGCGKTTTSQTLVNLFPDSWGHIQNDDITGKDKSQLMKKSLELLSKKEIKCVIVDRNNHQFRERKQLFEWLNELKEDYLVYDTNIKVIGVSFAPYDKLSEIRDITLQRVIKRGNNHQSIKWDELGEKKVVGIMNGFLKRYQPVNLDKSPDNMFDLMIELDFGQADSSLTNAKQILNEIHKAYPILVPEIPKDDEIETAFRRSLDYKPTVRKIVGKGNNNQQKTPKLIKPTYISAKIENYDEIIELVKRCIASDAELTEKFKHLLASGKVQKELHITLGHVMSSREKEAKKLWKSYCNRYTDQITEYNNNRIENAQGSGNNQNTQVKTTDKLNFRLEKLCWDEKIIAIVVELSKDKDGCIIDENNEKIKGLCCQNKIPHITLCKLESGVKAVYSNVLCEKVESAEVDENIKVVKLDNSKEFVGSVYLNF
SIO_010081: YJL087C
subclass of: SO_0000673
so part of: YJL087C
location: complement(270002..272485)
location: region:270002-272485:-1
so has part: feature:270002-272485:-1:exon

NP_012448.1
type: Protein
SIO_000068: ncbiprotein

S000003623
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:270002-272485:-1:exon

YJL085W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: EXO70
locus tag: YJL085W
so part of: sequence
location: <272827..>274698
location: region:272827-274698:1
so has part: feature:272827-274698:1:exon
subclass of: SO_0000010

853359
type: Gene
SIO_000068: ncbigene

position:272827:1
position: 272827
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:274698:1
position: 274698
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:272827-274698:1:exon

YJL085W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: EXO70
locus tag: YJL085W
product: GTP-Rho binding exocyst subunit EXO70
transcript id: NM_001181518.1
SIO_010081: YJL085W
subclass of: SO_0000673
so part of: YJL085W
location: <272827..>274698
location: region:272827-274698:1
so has part: feature:272827-274698:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:272827-274698:1:exon

YJL085W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: EXO70
locus tag: YJL085W
experiment: EXISTENCE:curator inference:GO:0090522 vesicle tethering involved in exocytosis [PMID:8978675]
experiment: EXISTENCE:direct assay:GO:0000131 incipient cellular bud site [PMID:18195105]
experiment: EXISTENCE:direct assay:GO:0000145 exocyst [PMID:8978675]
experiment: EXISTENCE:direct assay:GO:0005546 phosphatidylinositol-4,5-bisphosphate binding [PMID:17717527]
experiment: EXISTENCE:direct assay:GO:0005628 prospore membrane [PMID:24390141]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:17717527]
experiment: EXISTENCE:direct assay:GO:0005934 cellular bud tip [PMID:10207081|PMID:17717527|PMID:18946089|PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:18946089|PMID:22842922|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0007266 Rho protein signal transduction [PMID:19955214]
experiment: EXISTENCE:direct assay:GO:0031267 small GTPase binding [PMID:10588647]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:19053807]
experiment: EXISTENCE:genetic interaction:GO:0006887 exocytosis [PMID:15583030|PMID:17717527]
experiment: EXISTENCE:genetic interaction:GO:0007266 Rho protein signal transduction [PMID:19955214]
experiment: EXISTENCE:genetic interaction:GO:0051601 exocyst localization [PMID:17717527|PMID:18946089]
experiment: EXISTENCE:mutant phenotype:GO:0001927 exocyst assembly [PMID:15583030|PMID:18946089]
experiment: EXISTENCE:mutant phenotype:GO:0006887 exocytosis [PMID:17339375]
experiment: EXISTENCE:mutant phenotype:GO:0006893 Golgi to plasma membrane transport [PMID:17339375]
experiment: EXISTENCE:physical interaction:GO:0007266 Rho protein signal transduction [PMID:19955214]
experiment: EXISTENCE:physical interaction:GO:0031267 small GTPase binding [PMID:10207081|PMID:19955214]
note: Subunit of the exocyst complex; the exocyst mediates polarized targeting and tethering of post-Golgi secretory vesicles to active sites of exocytosis prior to SNARE-mediated fusion; PtdIns[4,5]P2-binding protein that localizes to exocytic sites in an actin-independent manner, targeting and anchoring the exocyst with Sec3p; involved in exocyst assembly; direct downstream effector of Rho3p and Cdc42p; relocalizes from bud neck to cytoplasm upon DNA replication stress
codon start: 1
product: GTP-Rho binding exocyst subunit EXO70
translation: MPAEIDIDEADVLVLSQELQKTSKLTFEINKSLKKIAATSNQSSQLFTPILARNNVLTTLQRNIESTLNSVASVKDLANEASKYEIILQKGINQVGLKQYTQVVHKLDDMLEDIQSGQANREENSEFHGILTHLEQLIKRSEAQLRVYFISILNSIKPFDPQINITKKMPFPYYEDQQLGALSWILDYFHGNSEGSIIQDILVGERSKLILKCMAFLEPFAKEISTAKNAPYEKGSSGMNSYTEALLGFIANEKSLVDDLYSQYTESKPHVLSQILSPLISAYAKLFGANLKIVRSNLENFGFFSFELVESINDVKKSLRGKELQNYNLLQDCTQEVRQVTQSLFRDAIDRIIKKANSISTIPSNNGVTEATVDTMSRLRKFSEYKNGCLGAMDNITRENWLPSNYKEKEYTLQNEALNWEDHNVLLSCFISDCIDTLAVNLERKAQIALMPNQEPDVANPNSSKNKHKQRIGFFILMNLTLVEQIVEKSELNLMLAGEGHSRLERLKKRYISYMVSDWRDLTANLMDSVFIDSSGKKSKDKEQIKEKFRKFNEGFEDLVSKTKQYKLSDPSLKVTLKSEIISLVMPMYERFYSRYKDSFKNPRKHIKYTPDELTTVLNQLVR
SIO_010081: YJL085W
subclass of: SO_0000673
so part of: YJL085W
location: 272827..274698
location: region:272827-274698:1
so has part: feature:272827-274698:1:exon

NP_012450.1
type: Protein
SIO_000068: ncbiprotein

S000003621
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:272827-274698:1:exon

YJL084C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ART3
gene: ALY2
locus tag: YJL084C
gene synonym: ART3
so part of: sequence
location: complement(<274862..>278002)
location: region:274862-278002:-1
so has part: feature:274862-278002:-1:exon
subclass of: SO_0000010

853361
type: Gene
SIO_000068: ncbigene

position:274862:-1
position: 274862
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:278002:-1
position: 278002
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:274862-278002:-1:exon

YJL084C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ART3
gene: ALY2
locus tag: YJL084C
gene synonym: ART3
product: Aly2p
transcript id: NM_001181517.1
SIO_010081: YJL084C
subclass of: SO_0000673
so part of: YJL084C
location: complement(<274862..>278002)
location: region:274862-278002:-1
so has part: feature:274862-278002:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:274862-278002:-1:exon

YJL084C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ART3
gene: ALY2
locus tag: YJL084C
gene synonym: ART3
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005769 early endosome [PMID:20739461]
experiment: EXISTENCE:direct assay:GO:0005770 late endosome [PMID:20739461]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0032386 regulation of intracellular transport [PMID:20739461]
experiment: EXISTENCE:mutant phenotype:GO:0070086 ubiquitin-dependent endocytosis [PMID:32800549]
experiment: EXISTENCE:mutant phenotype:GO:2000397 positive regulation of ubiquitin-dependent endocytosis [PMID:20956561]
experiment: EXISTENCE:physical interaction:GO:0030674 protein-macromolecule adaptor activity [PMID:20956561]
experiment: EXISTENCE:physical interaction:GO:0031625 ubiquitin protein ligase binding [PMID:18976803]
note: Alpha arrestin, Ub-ligase adaptor for Rsp5p; controls nutrient limitation-mediated endosomal recycling of the Gap1p amino acid permease; PY motif-containing adaptor involved in substrate-induced, Rsp5p-mediated ubiquitination and endocytosis of select plasma membrane localized amino acid transporters, such as Dip5p and Put4p; phosphorylated by Npr1p and by the Pcl7p-Pho85p cyclin-CDK complex; interacts with AP-1 subunit Apl4p
codon start: 1
product: Aly2p
translation: MPMDQSISSPLFPMEKDIDIPLDATPLAQSSSLQLFIHLAEPVVFLQGFDPQKTEYPSVVLRGCLVVRILKPTKLKSISLSFKGYSRTEWPEGIPPKRQEFVEIKDIVDHTWALYPPTEQKSKKKMDASAPNESNNAANNFLTKESGASLYRTLSDNETITSRKNSISGLSSLNLSPLGAPGNSSVNVKDRESRQRSRSSSVTSSNGPSRNLSPINLLKRATSPSVSHHNYKPTTTSIFSDLLNNTFTHNDAASHHGHHIPTSSNHLAMTSNNFTSGSGGEFFVFQPGDYIYAFEELIPQAYPESIKADFGFVEYFLFASIERPGAFKSNISARQVVNIVRTQAHNSVEESEPIIISRDWENQLYYDIVIASKDIILDAFLPITFKFAPLDKVTLHRIRIYVTETMEYYCREKKVHRMEPTKKFLLTEQKGPKLPNLPNDANLSKAKNMGNLLQDPKNGDLVNKEYEYQIFIPSRFNNHQQLHPDTSYENIKANHWIKICLRLSRVVDNKRKHYEISIDSPIHVLHRLCSHANTLLPSYDGHPASFPKETDSSISSILESSDDNINLYHNSNIFFPKEVLSSPVLSPNVQPLDILIPHLPSTSLTRNSRQFNRNSKSHPSDNTIFNSAKLKSNIYQPESLQRELASPQAIPLSPITSPMSNMEVPPPDFDFSSDFISDAASGTTTTEVSSSESSILPRDPPSYKDTVLHDNNQKRRPNSKHPTPPSLKASHPNKNSDKNSSETLNKKESMSKIEENKHKRETTPKKRENRDVKSLSTPQREESKDSTSTGNQSNEKNRKRVLSLSSSLHSSPNNSGFAHSALGNLSNESLRSLNRRESVQDNLPSTIRHDNPFFTDLNQVLIEDELKNHDKNELNRHSTNTSSTPASARSSFDYSGINISKDKLNMEPLLSKTETLTNKVNEDSFLRPNDSYVDLLEPSVDTTIDITAPYARNSSAWHPLQNDNDNNQFSPLLGSNENFLNAANAQNSAESDHNNDIFTQGSGLTESSKNSDSEERFISRLSSPEKVLINTLDNESGLQSINESTL
SIO_010081: YJL084C
subclass of: SO_0000673
so part of: YJL084C
location: complement(274862..278002)
location: region:274862-278002:-1
so has part: feature:274862-278002:-1:exon

NP_012451.1
type: Protein
SIO_000068: ncbiprotein

S000003620
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:274862-278002:-1:exon

YJL083W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TAX4
locus tag: YJL083W
so part of: sequence
location: <278841..>280655
location: region:278841-280655:1
so has part: feature:278841-280655:1:exon
subclass of: SO_0000010

853362
type: Gene
SIO_000068: ncbigene

position:278841:1
position: 278841
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:280655:1
position: 280655
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:278841-280655:1:exon

YJL083W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TAX4
locus tag: YJL083W
product: Tax4p
transcript id: NM_001181516.1
SIO_010081: YJL083W
subclass of: SO_0000673
so part of: YJL083W
location: <278841..>280655
location: region:278841-280655:1
so has part: feature:278841-280655:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:278841-280655:1:exon

YJL083W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TAX4
locus tag: YJL083W
experiment: EXISTENCE:direct assay:GO:0000407 phagophore assembly site [PMID:18298591]
experiment: EXISTENCE:genetic interaction:GO:0006914 autophagy [PMID:18298591]
experiment: EXISTENCE:genetic interaction:GO:0009267 cellular response to starvation [PMID:18298591]
experiment: EXISTENCE:genetic interaction:GO:0031505 fungal-type cell wall organization [PMID:15265867]
experiment: EXISTENCE:genetic interaction:GO:0048017 inositol lipid-mediated signaling [PMID:15265867]
note: EH domain-containing protein; involved in regulating phosphatidylinositol 4,5-bisphosphate levels and autophagy; Irs4p and Tax4p bind and activate the PtdIns phosphatase Inp51p; Irs4p and Tax4p are involved in localizing Atg17p to the PAS; TAX4 has a paralog, IRS4, that arose from the whole genome duplication
codon start: 1
product: Tax4p
translation: MHFPKKKHSGNLSVVELPKEALQDSLTAAQITFKRYAHPNGNAGSAERPRHLKVESAPVVKSEPSLPRMRQPEPRSINHQYSRETLPGHSEAFSVPTTPLQTIHYDVRNKASNSPSSIAAAETAAYLAHTNSFSNRSSGVGSRDPVMDTETKPPRAPSALKNELQLNRMRIPPPSYDNNVRSRSISPQVSYSTSLSSSCSISSDGEETSYREKSTDEAFPPEPSMSSYSLASKASAKASLTDPSQRQQESDYTAMNKLNGGNIIYKGTLPDLIPRSQRKTSKPRFKHRLLRSPEQQQENLSRVYSDQTQNGRAIINTQQNVKLKTTMRRGKYAITDNDETFPYDRKSVSSDSDTDEDSNVMEIKDKKKKSRRSKIKKGLKTTAAVVGSSTSVLPFPHHHHHHHQLHNPNSHHLHTHHHTSSHKFNEDKPWKSHRDLGFITEQERKRYESMWVSNRYSYLRLLPWWPSLANEDDESHLQPLNLPQDGLMLNLVVKDIWYRSNLPRDLLVQIYNMVDTRKDGTLDRKSFIVGMWLVDQCLYGRKLTNELDQRVWNSVDGYVLGTINVKPATSDHYHNANNPLDKPSKLSVRQELKNIKRDLRNVRI
SIO_010081: YJL083W
subclass of: SO_0000673
so part of: YJL083W
location: 278841..280655
location: region:278841-280655:1
so has part: feature:278841-280655:1:exon

NP_012452.1
type: Protein
SIO_000068: ncbiprotein

S000003619
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:278841-280655:1:exon

YJL082W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: IML2
locus tag: YJL082W
so part of: sequence
location: <281185..>283380
location: region:281185-283380:1
so has part: feature:281185-283380:1:exon
subclass of: SO_0000010

853363
type: Gene
SIO_000068: ncbigene

position:281185:1
position: 281185
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:283380:1
position: 283380
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:281185-283380:1:exon

YJL082W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: IML2
locus tag: YJL082W
product: Iml2p
transcript id: NM_001181515.1
SIO_010081: YJL082W
subclass of: SO_0000673
so part of: YJL082W
location: <281185..>283380
location: region:281185-283380:1
so has part: feature:281185-283380:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:281185-283380:1:exon

YJL082W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: IML2
locus tag: YJL082W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005741 mitochondrial outer membrane [PMID:16407407]
experiment: EXISTENCE:mutant phenotype:GO:0071218 cellular response to misfolded protein [PMID:26004510]
note: Protein required for clearance of inclusion bodies; localizes to the inclusion bodies formed under protein misfolding stress; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; protein abundance increases in response to DNA replication stress; IML2 has a paralog, YKR018C, that arose from the whole genome duplication
codon start: 1
product: Iml2p
translation: MFRVFGSFGSKGNQSSGEEQSTKTKQVLKQANDFEIALKAMDFVLDDRTDEGLNLLKKAEMETGSDQTILTLARGVIEFLQATLSFETEEMKRAAITLGKAEQMSWKSKQNAEKTNFRSSSIYPPGTVYAVTYTESCLLHALLMLFSESMMEAAKALLKLRRAYTMLQDIMVTVKKAERSKNSSSPSPSEKSQESCGSFVSAETTFISVDIPYKLSSEDKSNPLLLEFAEKIYTMRMGRLSGAHIGNTPSFHRLRDDLGLQTTPSQASDRHSVSDDFDLEQATIDEFIHSGANLCYGILQVVLSLLPPAIGAVLSIVGFKGSREEGLRLVWKATKERNVHGCIGLLGLMFYYDGPFQFTDADFDIPPNDNGSRALNKSRTNDSSLLPGYMDSATLLHPGKILEDALLKARALFPNSALWLLNEAKMLAGKGRLRDSLALMDSIDVNSIRMRQVKSLMVFERAILLVNLHEYNRAADDLISLLDISDWSHALYTYFAGCCYLENWRMTQLGLLNDGKEQFYKERARELIFDAPSLLGKKTFKSKNLPLDRFMLRKVQQFNNMQKKLNLQEPLDSIATSPVHELAYFYNGYNRMTENDLILTKKMLTEYHNPAIDSEDPDQELIRNLLLSLTLRRLGDAERGLALLDDIVLPKIFYIQNGKVKYFKKTEDPWAYPAALYERALFCWKLGGMESLNECREWLLRAQNYAADYELSTRIGMKIKAALDRVENALA
SIO_010081: YJL082W
subclass of: SO_0000673
so part of: YJL082W
location: 281185..283380
location: region:281185-283380:1
so has part: feature:281185-283380:1:exon

NP_012453.1
type: Protein
SIO_000068: ncbiprotein

S000003618
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:281185-283380:1:exon

YJL081C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ACT3
gene: ARP4
locus tag: YJL081C
gene synonym: ACT3
so part of: sequence
location: complement(<283802..>285271)
location: region:283802-285271:-1
so has part: feature:283802-285271:-1:exon
subclass of: SO_0000010

853364
type: Gene
SIO_000068: ncbigene

position:283802:-1
position: 283802
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:285271:-1
position: 285271
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:283802-285271:-1:exon

YJL081C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ACT3
gene: ARP4
locus tag: YJL081C
gene synonym: ACT3
product: Arp4p
transcript id: NM_001181514.1
SIO_010081: YJL081C
subclass of: SO_0000673
so part of: YJL081C
location: complement(<283802..>285271)
location: region:283802-285271:-1
so has part: feature:283802-285271:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:283802-285271:-1:exon

YJL081C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ACT3
gene: ARP4
locus tag: YJL081C
gene synonym: ACT3
experiment: EXISTENCE:direct assay:GO:0000785 chromatin [PMID:10436015]
experiment: EXISTENCE:direct assay:GO:0000812 Swr1 complex [PMID:14645854|PMID:14690608|PMID:16299513]
experiment: EXISTENCE:direct assay:GO:0003682 chromatin binding [PMID:10436015]
experiment: EXISTENCE:direct assay:GO:0005524 ATP binding [PMID:16088870]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:10911987|PMID:11011149]
experiment: EXISTENCE:direct assay:GO:0006281 DNA repair [PMID:12353039|PMID:16135807]
experiment: EXISTENCE:direct assay:GO:0006338 chromatin remodeling [PMID:14645854]
experiment: EXISTENCE:direct assay:GO:0006357 regulation of transcription by RNA polymerase II [PMID:10911987]
experiment: EXISTENCE:direct assay:GO:0016573 histone acetylation [PMID:10911987]
experiment: EXISTENCE:direct assay:GO:0035267 NuA4 histone acetyltransferase complex [PMID:10911987]
experiment: EXISTENCE:direct assay:GO:0042393 histone binding [PMID:10911987]
experiment: EXISTENCE:mutant phenotype:GO:0006281 DNA repair [PMID:15610740]
experiment: EXISTENCE:mutant phenotype:GO:0006325 chromatin organization [PMID:10436015]
experiment: EXISTENCE:mutant phenotype:GO:0006355 regulation of DNA-templated transcription [PMID:8598290]
experiment: EXISTENCE:mutant phenotype:GO:0051382 kinetochore assembly [PMID:17452364]
experiment: EXISTENCE:physical interaction:GO:0031011 Ino80 complex [PMID:10952318|PMID:24034245]
note: Nuclear actin-related protein involved in chromatin remodeling; component of chromatin-remodeling enzyme complexes
codon start: 1
product: Arp4p
translation: MSNAALQVYGGDEVSAVVIDPGSYTTNIGYSGSDFPQSILPSVYGKYTADEGNKKIFSEQSIGIPRKDYELKPIIENGLVIDWDTAQEQWQWALQNELYLNSNSGIPALLTEPVWNSTENRKKSLEVLLEGMQFEACYLAPTSTCVSFAAGRPNCLVVDIGHDTCSVSPIVDGMTLSKSTRRNFIAGKFINHLIKKALEPKEIIPLFAIKQRKPEFIKKTFDYEVDKSLYDYANNRGFFQECKETLCHICPTKTLEETKTELSSTAKRSIESPWNEEIVFDNETRYGFAEELFLPKEDDIPANWPRSNSGVVKTWRNDYVPLKRTKPSGVNKSDKKVTPTEEKEQEAVSKSTSPAANSADTPNETGKRPLEEEKPPKENNELIGLADLVYSSIMSSDVDLRATLAHNVVLTGGTSSIPGLSDRLMTELNKILPSLKFRILTTGHTIERQYQSWLGGSILTSLGTFHQLWVGKKEYEEVGVERLLNDRFR
SIO_010081: YJL081C
subclass of: SO_0000673
so part of: YJL081C
location: complement(283802..285271)
location: region:283802-285271:-1
so has part: feature:283802-285271:-1:exon

NP_012454.1
type: Protein
SIO_000068: ncbiprotein

S000003617
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:283802-285271:-1:exon

YJL080C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SCP160
locus tag: YJL080C
so part of: sequence
location: complement(<285558..>289226)
location: region:285558-289226:-1
so has part: feature:285558-289226:-1:exon
subclass of: SO_0000010

853365
type: Gene
SIO_000068: ncbigene

position:285558:-1
position: 285558
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:289226:-1
position: 289226
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:285558-289226:-1:exon

YJL080C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SCP160
locus tag: YJL080C
product: Scp160p
transcript id: NM_001181513.1
SIO_010081: YJL080C
subclass of: SO_0000673
so part of: YJL080C
location: complement(<285558..>289226)
location: region:285558-289226:-1
so has part: feature:285558-289226:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:285558-289226:-1:exon

YJL080C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SCP160
locus tag: YJL080C
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0003723 RNA binding [PMID:11278502]
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:22832273|PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:11278502]
experiment: EXISTENCE:direct assay:GO:0005844 polysome [PMID:11278502]
experiment: EXISTENCE:direct assay:GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network [PMID:8533468]
experiment: EXISTENCE:genetic interaction:GO:0000750 pheromone-dependent signal transduction involved in conjugation with cellular fusion [PMID:14536090]
experiment: EXISTENCE:genetic interaction:GO:0031509 subtelomeric heterochromatin formation [PMID:16632467]
experiment: EXISTENCE:mutant phenotype:GO:0007059 chromosome segregation [PMID:8533468]
experiment: EXISTENCE:mutant phenotype:GO:0030466 silent mating-type cassette heterochromatin formation [PMID:16632467]
experiment: EXISTENCE:mutant phenotype:GO:0031509 subtelomeric heterochromatin formation [PMID:16632467]
experiment: EXISTENCE:mutant phenotype:GO:0043577 chemotropism [PMID:22832273]
experiment: EXISTENCE:mutant phenotype:GO:0045141 meiotic telomere clustering [PMID:16632467]
experiment: EXISTENCE:physical interaction:GO:0001965 G-protein alpha-subunit binding [PMID:14536090]
note: Essential RNA-binding G protein effector of mating response pathway; ligand-activated RNA-binding protein that delivers RNAs involved in polarization and perpetualizing mating signal to shmoo tip during pheromone signaling; Scp160p-mediated RNA trafficking essential for chemotropism and successful mating; mainly associated with nuclear envelope and ER, interacts in mRNA-dependent manner with translating ribosomes via multiple KH domains, similar to vertebrate vigilins
codon start: 1
product: Scp160p
translation: MSEEQTAIDSPPSTVEGSVETVTTIDSPSTTASTIAATAEEHPQLEKKPTPLPSLKDLPSLGSNAAFANVKVSWGPNMKPAVSNSPSPSPSAPSLTTGLGAKRMRSKNIQEAFTLDLQSQLSITKPELSRIVQSVKKNHDVSVESTLSKNARTFLVSGVAANVHEAKRELVKKLTKPINAVIEVPSKCKASIIGSGGRTIREISDAYEVKINVSKEVNENSYDEDMDDTTSNVSLFGDFESVNLAKAKILAIVKEETKNATIKLVVEDEKYLPYIDVSEFASDEGDEEVKVQFYKKSGDIVILGPREKAKATKTSIQDYLKKLASNLDEEKVKIPSKFQFLIDAEELKEKYNVIVTFPSTPDDELVSFVGLRDKVGEAITYARSSSKSYVVESLDISKAHSKNLTHAKNLIMYFTKYSVLKGLEESHPNVKISLPSIQSLPTAETVTIHISAKSDEANDIKAVRKELISFVNNIPPSETLVITDLDYELFGGSIKHCLLASESSVAFVQFGDYYPNDNSILLVALTEDEDFKPSIEEIQASLNKANESLNSLRTKQNNMETKTYEFSEEVQDSLFKPSSATWKLIMEDISEQEGHLQIKLHTPEENQLTVRGDEKAAKAANKIFESILNSPSSKSKMTVNIPANSVARLIGNKGSNLQQIREKFACQIDIPNEENNNASKDKTVEVTLTGLEYNLTHAKKYLAAEAKKWADIITKELIVPVKFHGSLIGPHGTYRNRLQEKYNVFINFPRDNEIVTIRGPSRGVNKAHEELKALLDFEMENGHKMVINVPAEHVPRIIGKNGDNINDIRAEYGVEMDFLQKSTDPKAQETGEVELEITGSRQNIKDAAKRVESIVAEASDFVTEVLKIDHKYHKSIVGSGGHILREIISKAGGEEIRNKSVDIPNADSENKDITVQGPQKFVKKVVEEINKIVKDAENSVTKTIDIPAERKGALIGPGGIVRRQLESEFNINLFVPNKDDPSGKITITGAPENVEKAEKKILNEIIRENFDREVDVPASIYEYVSERGAFIQKLRMDLSVNVRFGNTSKKANKLARAPIEIPLEKVCGSTEGENAEKTKFTIEEVGAPTSSEEGDITMRLTYEPIDLSSILSDGEEKEVTKDTSNDSAKKEEALDTAVKLIKERIAKAPSATYAGYVWGADTRRFNMIVGPGGSNIKKIREAADVIINVPRKSDKVNDVVYIRGTKAGVEKAGEMVLKSLRR
SIO_010081: YJL080C
subclass of: SO_0000673
so part of: YJL080C
location: complement(285558..289226)
location: region:285558-289226:-1
so has part: feature:285558-289226:-1:exon

NP_012455.1
type: Protein
SIO_000068: ncbiprotein

S000003616
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:285558-289226:-1:exon

YJL079C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PRY1
locus tag: YJL079C
so part of: sequence
location: complement(<289875..>290774)
location: region:289875-290774:-1
so has part: feature:289875-290774:-1:exon
subclass of: SO_0000010

853366
type: Gene
SIO_000068: ncbigene

position:289875:-1
position: 289875
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:290774:-1
position: 290774
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:289875-290774:-1:exon

YJL079C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PRY1
locus tag: YJL079C
product: sterol-binding protein
transcript id: NM_001181512.1
SIO_010081: YJL079C
subclass of: SO_0000673
so part of: YJL079C
location: complement(<289875..>290774)
location: region:289875-290774:-1
so has part: feature:289875-290774:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:289875-290774:-1:exon

YJL079C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PRY1
locus tag: YJL079C
experiment: EXISTENCE:direct assay:GO:0000287 magnesium ion binding [PMID:27344972]
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005504 fatty acid binding [PMID:28365570]
experiment: EXISTENCE:direct assay:GO:0005576 extracellular region [PMID:11935221]
experiment: EXISTENCE:direct assay:GO:0005635 nuclear envelope [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0015485 cholesterol binding [PMID:27344972]
experiment: EXISTENCE:direct assay:GO:0032934 sterol binding [PMID:23027975]
experiment: EXISTENCE:genetic interaction:GO:0015908 fatty acid transport [PMID:28365570]
experiment: EXISTENCE:genetic interaction:GO:0015918 sterol transport [PMID:23027975]
experiment: EXISTENCE:mutant phenotype:GO:0005504 fatty acid binding [PMID:28365570]
experiment: EXISTENCE:mutant phenotype:GO:0015918 sterol transport [PMID:23027975]
experiment: EXISTENCE:mutant phenotype:GO:0032934 sterol binding [PMID:23027975]
note: Lipid binding protein; binds to both free fatty acids with preference for saturated long-chain fatty acids and to sterols; contains two independent lipid-binding sites; involved in the export of free fatty acids and acetylated sterols; export functions are redundant with PRY2, and PRY3; important for survival of cells that accumulate free fatty acids; involved in detoxification of hydrophobic compounds; secreted glycoprotein and member of the CAP/SCP protein superfamily
codon start: 1
product: sterol-binding protein
translation: MKLSKLSILTSALATSALAAPAVVTVTEHAHEAAVVTVQGVVYVENGQTRTTYETLAPASTATPTSTATALVAPPVAPSSASSNSDVVLSALKNLASVWGKTTDSTTTLTSSESTSQSLAQATTTSTPAAASTTSTPAATTTTSQAAATSSASSSDSDLSDFASSVLAEHNKKRALHKDTPALSWSDTLASYAQDYADNYDCSGTLTHSGGPYGENLALGYDGPAAVDAWYNEISNYDFSNPGFSSNTGHFTQVVWKSTTQVGCGIKTCGGAWGDYVICSYDPAGNYEGEYADNVEPLA
SIO_010081: YJL079C
subclass of: SO_0000673
so part of: YJL079C
location: complement(289875..290774)
location: region:289875-290774:-1
so has part: feature:289875-290774:-1:exon

NP_012456.1
type: Protein
SIO_000068: ncbiprotein

S000003615
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:289875-290774:-1:exon

YJL078C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PRY3
locus tag: YJL078C
so part of: sequence
location: complement(<291336..>293981)
location: region:291336-293981:-1
so has part: feature:291336-293981:-1:exon
subclass of: SO_0000010

853367
type: Gene
SIO_000068: ncbigene

position:291336:-1
position: 291336
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:293981:-1
position: 293981
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:291336-293981:-1:exon

YJL078C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PRY3
locus tag: YJL078C
product: Pry3p
transcript id: NM_001181511.1
SIO_010081: YJL078C
subclass of: SO_0000673
so part of: YJL078C
location: complement(<291336..>293981)
location: region:291336-293981:-1
so has part: feature:291336-293981:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:291336-293981:-1:exon

YJL078C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PRY3
locus tag: YJL078C
experiment: EXISTENCE:direct assay:GO:0009277 fungal-type cell wall [PMID:10383953|PMID:15781460|PMID:32554483]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0015908 fatty acid transport [PMID:28365570]
experiment: EXISTENCE:mutant phenotype:GO:0000747 conjugation with cellular fusion [PMID:32554483]
experiment: EXISTENCE:mutant phenotype:GO:0015918 sterol transport [PMID:23027975]
note: GPI-anchored cell wall protein involved in export of sterols; redundant role with PRY1 and PRY2 in the export of free fatty acids; role in mating efficiency; expression of full-length transcript is daughter cell-specific; in response to alpha factor, a short transcript starting at +452 is expressed and the long form is repressed by Ste12p; member of the CAP protein superfamily (cysteine-rich secretory proteins (CRISP), antigen 5, and pathogenesis related 1 proteins)
codon start: 1
product: Pry3p
translation: MLEFPISVLLGCLVAVKAQTTFPNFESDVLNEHNKFRALHVDTAPLTWSDTLATYAQNYADQYDCSGVLTHSDGPYGENLALGYTDTGAVDAWYGEISKYNYSNPGFSESTGHFTQVVWKSTAEIGCGYKYCGTTWNNYIVCSYNPPGNYLGEFAEEVEPLISTVSSSSSSSSSTSTTSDTVSTISSSIMPAVAQGYTTTVSSAASSSSLKSTTINPAKTATLTASSSTVITSSTESVGSSTVSSASSSSVTTSYATSSSTVVSSDATSSTTTTSSVATSSSTTSSDPTSSTAAASSSDPASSSAAASSSASTENAASSSSAISSSSSMVSAPLSSTLTTSTASSRSVTSNSVNSVKFANTTVFSAQTTSSVSASLSSSVAADDIQGSTSKEATSSVSEHTSIVTSATNAAQYATRLGSSSRSSSGAVSSSAVSQSVLNSVIAVNTDVSVTSVSSTAHTTKDTATTSVTASESITSETAQASSSTEKNISNSAATSSSIYSNSASVSGHGVTYAAEYAITSEQSSALATSVPATNCSSIVKTTTLENSSTTTITAITKSTTTLATTANNSTRAATAVTIDPTLDPTDNSASPTDNAKHTSTYGSSSTGASLDSLRTTTSISVSSNTTQLVSTCTSESDYSDSPSFAISTATTTESNLITNTITASCSTDSNFPTSAASSTDETAFTRTISTSCSTLNGASTQTSELTTSPMKTNTVVPASSFPSTTTTCLENDDTAFSSIYTEVNAATIINPGETSSLASDFATSEKPNEPTSVKSTSNEGTSSTTTTYQQTVATLYAKPSSTSLGARTTTGSNGRSTTSQQDGSAMHQPTSSIYTQLKEGTSTTAKLSAYEGAATPLSIFQCNSLAGTIAAFVVAVLFAF
SIO_010081: YJL078C
subclass of: SO_0000673
so part of: YJL078C
location: complement(291336..293981)
location: region:291336-293981:-1
so has part: feature:291336-293981:-1:exon

NP_012457.1
type: Protein
SIO_000068: ncbiprotein

S000003614
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:291336-293981:-1:exon

YJL077W-B
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJL077W-B
so part of: sequence
location: <294047..>294145
location: region:294047-294145:1
so has part: feature:294047-294145:1:exon
subclass of: SO_0000010

1466467
type: Gene
SIO_000068: ncbigene

position:294047:1
position: 294047
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:294145:1
position: 294145
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:294047-294145:1:exon

YJL077W-B
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJL077W-B
product: uncharacterized protein
transcript id: NM_001184603.1
SIO_010081: YJL077W-B
subclass of: SO_0000673
so part of: YJL077W-B
location: <294047..>294145
location: region:294047-294145:1
so has part: feature:294047-294145:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:294047-294145:1:exon

YJL077W-B
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJL077W-B
note: hypothetical protein; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
codon start: 1
product: uncharacterized protein
translation: MPILVWQLPKSKKLKTLKYRICFREFFDRVET
SIO_010081: YJL077W-B
subclass of: SO_0000673
so part of: YJL077W-B
location: 294047..294145
location: region:294047-294145:1
so has part: feature:294047-294145:1:exon

NP_878104.1
type: Protein
SIO_000068: ncbiprotein

S000028662
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:294047-294145:1:exon

YJL077C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ICS3
locus tag: YJL077C
so part of: sequence
location: complement(<294666..>295061)
location: region:294666-295061:-1
so has part: feature:294666-295061:-1:exon
subclass of: SO_0000010

853368
type: Gene
SIO_000068: ncbigene

position:294666:-1
position: 294666
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:295061:-1
position: 295061
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:294666-295061:-1:exon

YJL077C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ICS3
locus tag: YJL077C
product: Ics3p
transcript id: NM_001181510.1
SIO_010081: YJL077C
subclass of: SO_0000673
so part of: YJL077C
location: complement(<294666..>295061)
location: region:294666-295061:-1
so has part: feature:294666-295061:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:294666-295061:-1:exon

YJL077C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ICS3
locus tag: YJL077C
experiment: EXISTENCE:mutant phenotype:GO:0055070 copper ion homeostasis [PMID:26127016]
note: Protein with a role in copper homeostasis; possible role in vacuolar sorting and processing of secretory proteins; null mutants are hypersensitive to sortin2
codon start: 1
product: Ics3p
translation: MHISLPTRNKSYFRIRTRTYQIGLYHSDSSPIRDISVLHLLIATLCTIFFPIFFSLSKVQVVQWQGTTISKNCIALTMSFPLNAIPGMYLIIAFPRLQTVIPLQRNTPVRITKSVIVKGAVSVPRISSPMH
SIO_010081: YJL077C
subclass of: SO_0000673
so part of: YJL077C
location: complement(294666..295061)
location: region:294666-295061:-1
so has part: feature:294666-295061:-1:exon

NP_012458.1
type: Protein
SIO_000068: ncbiprotein

S000003613
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:294666-295061:-1:exon

YJL077W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJL077W-A
so part of: sequence
location: <294799..>294885
location: region:294799-294885:1
so has part: feature:294799-294885:1:exon
subclass of: SO_0000010

13393612
type: Gene
SIO_000068: ncbigene

position:294799:1
position: 294799
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:294885:1
position: 294885
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:294799-294885:1:exon

YJL077W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJL077W-A
product: uncharacterized protein
transcript id: NM_001270753.1
SIO_010081: YJL077W-A
subclass of: SO_0000673
so part of: YJL077W-A
location: <294799..>294885
location: region:294799-294885:1
so has part: feature:294799-294885:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:294799-294885:1:exon

YJL077W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJL077W-A
note: hypothetical protein; mRNA identified as translated by ribosome profiling data; completely overlaps the verified gene YJL077C/ICS3
codon start: 1
product: uncharacterized protein
translation: MPGIAFKGKDMVKAIQFLEIVVPCHCTT
SIO_010081: YJL077W-A
subclass of: SO_0000673
so part of: YJL077W-A
location: 294799..294885
location: region:294799-294885:1
so has part: feature:294799-294885:1:exon

NP_001257682.1
type: Protein
SIO_000068: ncbiprotein

S000028661
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:294799-294885:1:exon

YJL076W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CFI1
alternative label: ESC5
alternative label: SRM8
gene: NET1
locus tag: YJL076W
gene synonym: CFI1; ESC5; SRM8
so part of: sequence
location: <295245..>298814
location: region:295245-298814:1
so has part: feature:295245-298814:1:exon
subclass of: SO_0000010

853369
type: Gene
SIO_000068: ncbigene

position:295245:1
position: 295245
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:298814:1
position: 298814
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:295245-298814:1:exon

YJL076W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CFI1
alternative label: ESC5
alternative label: SRM8
gene: NET1
locus tag: YJL076W
gene synonym: CFI1; ESC5; SRM8
product: Net1p
transcript id: NM_001181509.1
SIO_010081: YJL076W
subclass of: SO_0000673
so part of: YJL076W
location: <295245..>298814
location: region:295245-298814:1
so has part: feature:295245-298814:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:295245-298814:1:exon

YJL076W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CFI1
alternative label: ESC5
alternative label: SRM8
gene: NET1
locus tag: YJL076W
gene synonym: CFI1; ESC5; SRM8
experiment: EXISTENCE:direct assay:GO:0000182 rDNA binding [PMID:10219245]
experiment: EXISTENCE:direct assay:GO:0004864 protein phosphatase inhibitor activity [PMID:10219244]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:10219244]
experiment: EXISTENCE:direct assay:GO:0030869 RENT complex [PMID:10219244]
experiment: EXISTENCE:direct assay:GO:1902570 protein localization to nucleolus [PMID:33481703]
experiment: EXISTENCE:genetic interaction:GO:0001100 negative regulation of exit from mitosis [PMID:10219244]
experiment: EXISTENCE:mutant phenotype:GO:0000183 rDNA heterochromatin formation [PMID:10219245]
experiment: EXISTENCE:mutant phenotype:GO:0001100 negative regulation of exit from mitosis [PMID:10219244|PMID:26090959]
experiment: EXISTENCE:mutant phenotype:GO:0007000 nucleolus organization [PMID:10219245]
experiment: EXISTENCE:mutant phenotype:GO:1904751 positive regulation of protein localization to nucleolus [PMID:10219244]
note: Core subunit of the RENT complex; involved in nucleolar silencing and telophase exit; stimulates transcription by RNA polymerase I and regulates nucleolar structure; NET1 has a paralog, TOF2, that arose from the whole genome duplication
codon start: 1
product: Net1p
translation: MYKLQVVLVPPSLQATMPIQFGYGPTIAESSQLLPNRTNMAQSAGDASLQYANLRSANVSFTPSYFNQSRFRKFLLFTKPTNTLLNLSDEIIDKCEKMYPSLQEDIEILSLQDNSGCDLDPDFLVKDVFNVNNIVRVILKNEIDLDDSAPVSLYKSVKRSKLNNGSPQSVQPQQQIPSSSGVLRIAKKRPPTGTTTTTTIRSATNGSMRVSTPLARQIYPPPSSKIVSNNSDDEDEDIGERSFLPPPTQPQSPPIRISSGIDAGKKIKSSIVEEDIVSRSATVDPDKTKQQRLLSGTPIMSTMTPNRVTLTGQRVVSEHAHKNELVFSASASSSSFANGGTAAVTAQDINRKPPVTTPRITSGMLKIPEPRISEIEKELKEGPSSPASILPAKAAKIPMKKPYLENGENYESDDSSSSENQETPETEPHSKASLQRSQSSIADNNGSPVKNSPLGDAMPHNVHLAELPKASNTSITKSSNGESWGKQQEHQPPRKSSLETIVEKKSQAEPSGIVEPKRMTNFLDDNQVREKEDTNDKLLEKEILPTIPHNDQPILASSDKSNGTLKSLAGKVSSNNNASKEDGTIINGTIEDDGNDNDEVDTTVRIVPQDSDSSSFPKSDLFKMIEGDDTDLPQWFKGKNSRTSGNSKNSKPYTTVLNKDIDNSKPDPRNILPQRTPRSAAKRAAQLLAGAKKNEVPQKSTEDSSSAASTDDESESGIETDFSSDDDFKRKNMSVPNNGPKDISLHSLKGSVVPVKDSKIINKEVDEERNDKRDSQKKSAVSESSVTNSKISEQMAKSFYPNSNKKQNEATKVETKPATQASSFPVVGGSPSVATKGTTSFNEEGNRKNVKTKAKNESAQIDRQQKETTSRVADLKSANIGGEDLNKKAEGSKEPEKASANIQDANDKNNSKEKEDSKSKQVSQKKLKMTDHLKEGNVQLPKPSANDKLKDLKAKFTNSKTLVPPGIISNEKNNSSANDDDSSSSGSSTEDESSSSSSSSDEETSTSRKARRVVVNTPREPVRSSSKIEAPSPSVNKKINATPDKIPVTQLMDMSSPPSVKSKTTSNPSSILHDLPRKVRPSLSSLSDLVSRGIPDVKEKTSKSNEKSQTKAPSSSDDESSSDSDSNSSSDSVSDSSSDSKSESDSDDSGDSSDDGKSFISAKSASAALGKKKKPSGGFASLIKDFKKK
SIO_010081: YJL076W
subclass of: SO_0000673
so part of: YJL076W
location: 295245..298814
location: region:295245-298814:1
so has part: feature:295245-298814:1:exon

NP_012459.1
type: Protein
SIO_000068: ncbiprotein

S000003612
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:295245-298814:1:exon

YJL075C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: APQ13
locus tag: YJL075C
so part of: sequence
location: complement(<298460..>298876)
location: region:298460-298876:-1
so has part: feature:298460-298876:-1:exon
subclass of: SO_0000010

853370
type: Gene
SIO_000068: ncbigene

position:298460:-1
position: 298460
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:298876:-1
position: 298876
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:298460-298876:-1:exon

YJL075C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: APQ13
locus tag: YJL075C
product: Apq13p
transcript id: NM_001395035.1
SIO_010081: YJL075C
subclass of: SO_0000673
so part of: YJL075C
location: complement(<298460..>298876)
location: region:298460-298876:-1
so has part: feature:298460-298876:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:298460-298876:-1:exon

YJL075C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: APQ13
locus tag: YJL075C
note: hypothetical protein; not conserved in closely related Saccharomyces species; 85% of ORF overlaps verified gene NET1, but does not share all phenotypes; null mutant is slow-growing, sensitive to heat, sorbate, and other various chemicals
codon start: 1
product: Apq13p
translation: MLDYFFLLAFCDVYSTETFWYHFFLKSFINDANPPLGFFFLPKAALADFALIKLFPSSDESPESSESDSDLESELESDTESELELESESELDSSSLLEGAFVCDFSFDLEVFSFTSGMPLETRSDNELKEGRTFLGRS
SIO_010081: YJL075C
subclass of: SO_0000673
so part of: YJL075C
location: complement(298460..298876)
location: region:298460-298876:-1
so has part: feature:298460-298876:-1:exon

NP_001381965.1
type: Protein
SIO_000068: ncbiprotein

S000003611
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:298460-298876:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1010; Autonomously Replicating Sequence
so part of: sequence
location: 298981..299245
location: region:298981-299245:1
so has part: feature:298981-299245:1:region

S000028447
type: SGD
SIO_000068: sgd

position:298981:1
position: 298981
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:299245:1
position: 299245
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:298981-299245:1:region

YJL074C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SMC3
locus tag: YJL074C
so part of: sequence
location: complement(<299157..>302849)
location: region:299157-302849:-1
so has part: feature:299157-302849:-1:exon
subclass of: SO_0000010

853371
type: Gene
SIO_000068: ncbigene

position:299157:-1
position: 299157
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:302849:-1
position: 302849
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:299157-302849:-1:exon

YJL074C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SMC3
locus tag: YJL074C
product: cohesin subunit SMC3
transcript id: NM_001181507.1
SIO_010081: YJL074C
subclass of: SO_0000673
so part of: YJL074C
location: complement(<299157..>302849)
location: region:299157-302849:-1
so has part: feature:299157-302849:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:299157-302849:-1:exon

YJL074C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SMC3
locus tag: YJL074C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:15282802]
experiment: EXISTENCE:direct assay:GO:0016887 ATP hydrolysis activity [PMID:17055978]
experiment: EXISTENCE:direct assay:GO:0030892 mitotic cohesin complex [PMID:9990856]
experiment: EXISTENCE:genetic interaction:GO:0007064 mitotic sister chromatid cohesion [PMID:9335333]
experiment: EXISTENCE:mutant phenotype:GO:0006979 response to oxidative stress [PMID:34897432]
experiment: EXISTENCE:mutant phenotype:GO:0007130 synaptonemal complex assembly [PMID:10412984]
experiment: EXISTENCE:mutant phenotype:GO:0007131 reciprocal meiotic recombination [PMID:10412984]
experiment: EXISTENCE:mutant phenotype:GO:0051177 meiotic sister chromatid cohesion [PMID:10412984]
experiment: EXISTENCE:mutant phenotype:GO:1990414 replication-born double-strand break repair via sister chromatid exchange [PMID:16888651]
experiment: EXISTENCE:physical interaction:GO:0019901 protein kinase binding [PMID:27325700]
note: Subunit of the multiprotein cohesin complex; required for sister chromatid cohesion in mitotic cells; also required, with Rec8p, for cohesion and recombination during meiosis; phylogenetically conserved SMC chromosomal ATPase family member
codon start: 1
product: cohesin subunit SMC3
translation: MYIKRVIIKGFKTYRNETIIDNFSPHQNVIIGSNGSGKSNFFAAIRFVLSDDYSNLKREERQGLIHQGSGGSVMSASVEIVFHDPDHSMILPSGVLSRGDDEVTIRRTVGLKKDDYQLNDRNVTKGDIVRMLETAGFSMNNPYNIVPQGKIVALTNAKDKERLQLLEDVVGAKSFEVKLKASLKKMEETEQKKIQINKEMGELNSKLSEMEQERKELEKYNELERNRKIYQFTLYDRELNEVINQMERLDGDYNNTVYSSEQYIQELDKREDMIDQVSKKLSSIEASLKIKNATDLQQAKLRESEISQKLTNVNVKIKDVQQQIESNEEQRNLDSATLKEIKSIIEQRKQKLSKILPRYQELTKEEAMYKLQLASLQQKQRDLILKKGEYARFKSKDERDTWIHSEIEELKSSIQNLNELESQLQMDRTSLRKQYSAIDEEIEELIDSINGPDTKGQLEDFDSELIHLKQKLSESLDTRKELWRKEQKLQTVLETLLSDVNQNQRNVNETMSRSLANGIINVKEITEKLKISPESVFGTLGELIKVNDKYKTCAEVIGGNSLFHIVVDTEETATLIMNELYRMKGGRVTFIPLNRLSLDSDVKFPSNTTTQIQFTPLIKKIKYEPRFEKAVKHVFGKTIVVKDLGQGLKLAKKHKLNAITLDGDRADKRGVLTGGYLDQHKRTRLESLKNLNESRSQHKKILEELDFVRNELNDIDTKIDQVNGNIRKVSNDRESVLTNIEVYRTSLNTKKNEKLILEESLNAIILKLEKLNTNRTFAQEKLNTFENDLLQEFDSELSKEEKERLESLTKEISAAHNKLNITSDALEGITTTIDSLNAELESKLIPQENDLESKMSEVGDAFIFGLQDELKELQLEKESVEKQHENAVLELGTVQREIESLIAEETNNKKLLEKANNQQRLLLKKLDNFQKSVEKTMIKKTTLVTRREELQQRIREIGLLPEDALVNDFSDITSDQLLQRLNDMNTEISGLKNVNKRAFENFKKFNERRKDLAERASELDESKDSIQDLIVKLKQQKVNAVDSTFQKVSENFEAVFERLVPRGTAKLIIHRKNDNANDHDESIDVDMDAESNESQNGKDSEIMYTGVSISVSFNSKQNEQLHVEQLSGGQKTVCAIALILAIQMVDPASFYLFDEIDAALDKQYRTAVATLLKELSKNAQFICTTFRTDMLQVADKFFRVKYENKISTVIEVNREEAIGFIRGSNKFAEV
SIO_010081: YJL074C
subclass of: SO_0000673
so part of: YJL074C
location: complement(299157..302849)
location: region:299157-302849:-1
so has part: feature:299157-302849:-1:exon

NP_012461.1
type: Protein
SIO_000068: ncbiprotein

S000003610
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:299157-302849:-1:exon

YJL073W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: KAR8
gene: JEM1
locus tag: YJL073W
gene synonym: KAR8
so part of: sequence
location: <303181..>305118
location: region:303181-305118:1
so has part: feature:303181-305118:1:exon
subclass of: SO_0000010

853372
type: Gene
SIO_000068: ncbigene

position:303181:1
position: 303181
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:305118:1
position: 305118
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:303181-305118:1:exon

YJL073W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: KAR8
gene: JEM1
locus tag: YJL073W
gene synonym: KAR8
product: Jem1p
transcript id: NM_001181506.3
SIO_010081: YJL073W
subclass of: SO_0000673
so part of: YJL073W
location: <303181..>305118
location: region:303181-305118:1
so has part: feature:303181-305118:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:303181-305118:1:exon

YJL073W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: KAR8
gene: JEM1
locus tag: YJL073W
gene synonym: KAR8
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:9148890|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network [PMID:15282802]
experiment: EXISTENCE:genetic interaction:GO:0034975 protein folding in endoplasmic reticulum [PMID:9817751]
experiment: EXISTENCE:genetic interaction:GO:0051087 chaperone binding [PMID:9148890]
experiment: EXISTENCE:mutant phenotype:GO:0000742 karyogamy involved in conjugation with cellular fusion [PMID:10069807]
experiment: EXISTENCE:mutant phenotype:GO:0030433 ubiquitin-dependent ERAD pathway [PMID:11381090]
experiment: EXISTENCE:mutant phenotype:GO:0051082 unfolded protein binding [PMID:9148890]
note: DnaJ-like chaperone required for nuclear membrane fusion during mating; localizes to the ER membrane; exhibits genetic interactions with KAR2
codon start: 1
product: Jem1p
translation: MILISGYCLLVYSVILPVLISASKLCDLAELQRLNKNLKVDTESLPKYQWIAGQLEQNCMTADPASENMSDVIQLANQIYYKIGLIQLSNDQHLRAINTFEKIVFNETYKGSFGKLAEKRLQELYVDFGMWDKVHQKDDQYAKYLSLNETIRNKISSKDVSVEEDISELLRITPYDVNVLSTHIDVLFHKLAEEIDVSLAAAIILDYETILDKHLASLSIDTRLSIHYVISVLQTFVLNSDASFNIRKCLSIDMDYDKCKKLSLTISKLNKVNPSKRQILDPATYAFENKKFRSWDRIIEFYLKDKKPFITPMKILNKDTNFKNNYFFLEEIIKQLIEDVQLSRPLAKNLFEDPPITDGFVKPKSYYHTDYLVYIDSILCQASSMSPDVKRAKLAAPFCKKSLRHSLTLETWKHYQDAKSEQKPLPETVLSDVWNSNPHLLMYMVNSILNKSRSKPHSQFKKQLYDQINKFFQDNGLSESTNPYVMKNFRLLQKQLQTYKEHKHRNFNQQYFQQQQQQQQHQRHQAPPAAPNYDPKKDYYKILGVSPSASSKEIRKAYLNLTKKYHPDKIKANHNDKQESIHETMSQINEAYETLSDDDKRKEYDLSRSNPRRNTFPQGPRQNNMFKNPGSGFPFGNGFKMNFGL
SIO_010081: YJL073W
subclass of: SO_0000673
so part of: YJL073W
location: 303181..305118
location: region:303181-305118:1
so has part: feature:303181-305118:1:exon

NP_012462.3
type: Protein
SIO_000068: ncbiprotein

S000003609
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:303181-305118:1:exon

YJL072C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CDC102
gene: PSF2
locus tag: YJL072C
gene synonym: CDC102
so part of: sequence
location: complement(<305221..>305862)
location: region:305221-305862:-1
so has part: feature:305221-305862:-1:exon
subclass of: SO_0000010

853373
type: Gene
SIO_000068: ncbigene

position:305221:-1
position: 305221
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:305862:-1
position: 305862
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:305221-305862:-1:exon

YJL072C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CDC102
gene: PSF2
locus tag: YJL072C
gene synonym: CDC102
product: DNA replication protein PSF2
transcript id: NM_001181505.1
SIO_010081: YJL072C
subclass of: SO_0000673
so part of: YJL072C
location: complement(<305221..>305862)
location: region:305221-305862:-1
so has part: feature:305221-305862:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:305221-305862:-1:exon

YJL072C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CDC102
gene: PSF2
locus tag: YJL072C
gene synonym: CDC102
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:15282802]
experiment: EXISTENCE:direct assay:GO:0031298 replication fork protection complex [PMID:16531994]
experiment: EXISTENCE:direct assay:GO:0043596 nuclear replication fork [PMID:16103218]
experiment: EXISTENCE:direct assay:GO:0071162 CMG complex [PMID:26524492]
experiment: EXISTENCE:genetic interaction:GO:0006261 DNA-templated DNA replication [PMID:12730134]
experiment: EXISTENCE:mutant phenotype:GO:0000727 double-strand break repair via break-induced replication [PMID:20516198]
experiment: EXISTENCE:mutant phenotype:GO:0006261 DNA-templated DNA replication [PMID:12768207]
experiment: EXISTENCE:physical interaction:GO:0000811 GINS complex [PMID:12768207|PMID:12730134]
experiment: EXISTENCE:physical interaction:GO:0031261 DNA replication preinitiation complex [PMID:12730134]
note: Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p); complex is localized to DNA replication origins and implicated in assembly of the DNA replication machinery
codon start: 1
product: DNA replication protein PSF2
translation: MSLPAHLQQTFSPEEIQFIVENEPIKIFPRITTRQKIRGDDRGTGNHTRWQLITTDDKALNNMVAMRSTEVVLWIALLLKQQSKCSIVAPQWLTTKELDRKIQYEKTHPDRFSELPWNWLVLARILFNKAKDDFHDPIHELRGKIQDLREIRQIKVLKGLKYLNESHLQLDNLSLLEINELRPFITEIMDKLREIHTASLTAGTENDEEEFNI
SIO_010081: YJL072C
subclass of: SO_0000673
so part of: YJL072C
location: complement(305221..305862)
location: region:305221-305862:-1
so has part: feature:305221-305862:-1:exon

NP_012463.1
type: Protein
SIO_000068: ncbiprotein

S000003608
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:305221-305862:-1:exon

YJL071W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: HRB574
gene: ARG2
locus tag: YJL071W
gene synonym: HRB574
so part of: sequence
location: <306132..>307856
location: region:306132-307856:1
so has part: feature:306132-307856:1:exon
subclass of: SO_0000010

853374
type: Gene
SIO_000068: ncbigene

position:306132:1
position: 306132
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:307856:1
position: 307856
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:306132-307856:1:exon

YJL071W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: HRB574
gene: ARG2
locus tag: YJL071W
gene synonym: HRB574
product: acetyl-CoA:L-glutamate N-acetyltransferase
transcript id: NM_001181504.1
SIO_010081: YJL071W
subclass of: SO_0000673
so part of: YJL071W
location: <306132..>307856
location: region:306132-307856:1
so has part: feature:306132-307856:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:306132-307856:1:exon

YJL071W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: HRB574
gene: ARG2
locus tag: YJL071W
gene synonym: HRB574
EC number: 2.3.1.1
experiment: EXISTENCE:direct assay:GO:0004042 acetyl-CoA:L-glutamate N-acetyltransferase activity [PMID:11553611]
experiment: EXISTENCE:direct assay:GO:0005759 mitochondrial matrix [PMID:205532]
experiment: EXISTENCE:mutant phenotype:GO:0004042 acetyl-CoA:L-glutamate N-acetyltransferase activity [PMID:11553611]
experiment: EXISTENCE:mutant phenotype:GO:0006592 ornithine biosynthetic process [PMID:11553611]
note: Acetylglutamate synthase (glutamate N-acetyltransferase); mitochondrial enzyme that catalyzes the first step in the biosynthesis of the arginine precursor ornithine; forms a complex with Arg5,6p
codon start: 1
product: acetyl-CoA:L-glutamate N-acetyltransferase
translation: MWRRIFAHELKYDQPNASSKNLILSVLNTTATKREAKDYLSKYTNDSGQHNHCLFFIRDLHKVAPAILSQFSSVIKRLGMLGLRPMFVIPPSPTHVNIQAELLDSIVTEADLKPLHLKEGLTKSRTGLYHSVFSQESRFFDIGNSNFIPIVKPYVYNEETASEFMTKDVVKFMDCLCQGNIPHIDKFFILNNAGGIPSGERNDNAHVFINLSQELEHLSSSLSHNISTLTKREPRSQNLLHRMEVYVKKDEISSLECEYHDHLENLLLMDKVLSNLAATATGLITTVKAAALSSDRKNPLVYNLLTDRSLISSSLPRFKKKDGEIDSPANMFDDHAWYELPSQQVNAAPSNSDAVLVTTVLKKGVHIKTYDYKTLTQFNSIGLPKKFHVPEKGAKPSSNSPKLDINKFKSIIDQSFKRSLDLHDYIKRINGKIATIIVIGDYEGIAILTYEGSEENSFVYLDKFAVLPHLKGSLGISDIIFNLMFKKFPNEILWRSRKDNVVNKWYFQRSVAVLDLSIDLDPEHCDEKQSQFKLFYYGNPQYAKRALRDKKRLREFMRSVRDIKPSWENEKNIS
SIO_010081: YJL071W
subclass of: SO_0000673
so part of: YJL071W
location: 306132..307856
location: region:306132-307856:1
so has part: feature:306132-307856:1:exon

NP_012464.1
type: Protein
SIO_000068: ncbiprotein

S000003607
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:306132-307856:1:exon

YJL070C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJL070C
so part of: sequence
location: complement(<307971..>310637)
location: region:307971-310637:-1
so has part: feature:307971-310637:-1:exon
subclass of: SO_0000010

853375
type: Gene
SIO_000068: ncbigene

position:307971:-1
position: 307971
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:310637:-1
position: 310637
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:307971-310637:-1:exon

YJL070C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJL070C
product: metallo-dependent hydrolase superfamily protein
transcript id: NM_001181503.3
SIO_010081: YJL070C
subclass of: SO_0000673
so part of: YJL070C
location: complement(<307971..>310637)
location: region:307971-310637:-1
so has part: feature:307971-310637:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:307971-310637:-1:exon

YJL070C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJL070C
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
note: Putative metallo-dependent hydrolase superfamily protein; similar to AMP deaminases but lacks key catalytic residues and does not rescue purine nucleotide metabolic defect of quadruple aah1 ade8 amd1 his1 mutant; may regulate purine nucleotide homeostasis as overexpression in an AMD1 strain grown in adenine results in greatly reduced GDP and GTP intracellular levels; not an essential gene; YJL070C has a paralog, YBR284W, that arose from the whole genome duplication
codon start: 1
product: metallo-dependent hydrolase superfamily protein
translation: MQAVERRPSLLFDEYQNSVTKPNETKNKEARVLSENDGDVSPSVLKQKEISVDDMDMISLPTEFDRQMVLGSPMFFDLEDEENKIDPLPSVSHHYGNGESDSFVSSYTPSNLKTGEETKDLFINPFELVSQMRKRYIAASKQDGISNIKNDTEKWFLYPKPLPKFWRFEDDKRFQDPSDSDLNDDGDSTGTGAATPHRHGYYYPSYFTDHYYYYTKSGLKGKGNIKVPYTGEYFDLEDYKKQYIYHLSNQENTQNPLSPYSSKEESLEEEFLTDVPTFQEFRDDFAYIIELIQSHKFNEVSRKRLSYLLDKFELFQYLNSKKEILANKNVPYRDFYNSRKVDRDLSLSGCISQRQLSEYIWEKINLEPERIVYQDPETSRKLSLRDIFQFGCSSNDQPIAIGLKLIDDEFLDWYRNIYLIDYHLTPNKVAKLVGKEMRFYLLAKVFLEFDNFIEGEYLAEIFIKYVIHILEKSKYQLAQVSVNFQFYSSGEDWYKKFSQWLLRWKLVSYNIRWNIQIARIFPKLFKENVVSNFQEFLDLIFNPLFTLEKEQLPIDSSVNTDIIGLQFFLSNVCSMDLVIKESDEYYWKEFTDMNCKPKFWTAQGDNPTVAHYMYYIYKSLAKVNFLRSQNLQNTITLRNYCSPLSSRTSQFGVDLYFTDQVESLVCNLLLCNGGLLQVEPLWDTATMIQYLFYLFQIPILAAPLSSVSLLNSQKSTFLKNKNVLLEHDYLKDQETAKINPSRDITVGEQRSYETNPFMKMFKMGLKISLSSKSILYNSSYTLEPLIEEYSVAASIYLLNPTDLCELSRTSVLSSGYEGWYKAHWIGVGVKKAPYFEENVGGIDNWYDTAKDTSIKHNVPMIRRRYRKETLDQEWNFVRDHFGVINSIW
SIO_010081: YJL070C
subclass of: SO_0000673
so part of: YJL070C
location: complement(307971..310637)
location: region:307971-310637:-1
so has part: feature:307971-310637:-1:exon

NP_012465.3
type: Protein
SIO_000068: ncbiprotein

S000003606
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:307971-310637:-1:exon

YJL069C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: UTP18
locus tag: YJL069C
so part of: sequence
location: complement(<310922..>312706)
location: region:310922-312706:-1
so has part: feature:310922-312706:-1:exon
subclass of: SO_0000010

853376
type: Gene
SIO_000068: ncbigene

position:310922:-1
position: 310922
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:312706:-1
position: 312706
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:310922-312706:-1:exon

YJL069C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: UTP18
locus tag: YJL069C
product: Utp18p
transcript id: NM_001181502.1
SIO_010081: YJL069C
subclass of: SO_0000673
so part of: YJL069C
location: complement(<310922..>312706)
location: region:310922-312706:-1
so has part: feature:310922-312706:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:310922-312706:-1:exon

YJL069C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: UTP18
locus tag: YJL069C
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:15590835|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0030686 90S preribosome [PMID:12150911]
experiment: EXISTENCE:direct assay:GO:0032040 small-subunit processome [PMID:15590835]
experiment: EXISTENCE:direct assay:GO:0034388 Pwp2p-containing subcomplex of 90S preribosome [PMID:15231838|PMID:17515605]
experiment: EXISTENCE:mutant phenotype:GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:15590835]
experiment: EXISTENCE:mutant phenotype:GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:15590835]
experiment: EXISTENCE:mutant phenotype:GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:15590835]
note: Small-subunit processome protein involved in pre-18S rRNA maturation; part of a subunit of the 90S preribosomal particle capable of interacting directly with the 5' ETS of the 35S pre-rRNA; contains WD40 repeats
codon start: 1
product: Utp18p
translation: MTMATTAMNVSVPPPDEEEQLLAKFVFGDTTDLQENLAKFNADFIFNEQEMDVEDQEDEGSESDNSEEDEAQNGELDHVNNDQLFFVDDGGNEDSQDKNEDTMDVDDEDDSSSDDYSEDSEEAAWIDSDDEKIKVPILVTNKTKKLRTSYNESKINGVHYINRLRSQFEKIYPRPKWVDDESDSELDDEEDDEEEGSNNVINGDINALTKILSTTYNYKDTLSNSKLLPPKKLDIVRLKDANASHPSHSAIQSLSFHPSKPLLLTGGYDKTLRIYHIDGKTNHLVTSLHLVGSPIQTCTFYTSLSNQNQQNIFTAGRRRYMHSWDLSLENLTHSQTAKIEKFSRLYGHESTQRSFENFKVAHLQNSQTNSVHGIVLLQGNNGWINILHSTSGLWLMGCKIEGVITDFCIDYQPISRGKFRTILIAVNAYGEVWEFDLNKNGHVIRRWKDQGGVGITKIQVGGGTTTTCPALQISKIKQNRWLAVGSESGFVNLYDRNNAMTSSTPTPVAALDQLTTTISNLQFSPDGQILCMASRAVKDALRLVHLPSCSVFSNWPTSGTPLGKVTSVAFSPSGGLLAVGNEQGKVRLWKLNHY
SIO_010081: YJL069C
subclass of: SO_0000673
so part of: YJL069C
location: complement(310922..312706)
location: region:310922-312706:-1
so has part: feature:310922-312706:-1:exon

NP_012466.1
type: Protein
SIO_000068: ncbiprotein

S000003605
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:310922-312706:-1:exon

YJL068C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJL068C
so part of: sequence
location: complement(<313016..>313915)
location: region:313016-313915:-1
so has part: feature:313016-313915:-1:exon
subclass of: SO_0000010

853377
type: Gene
SIO_000068: ncbigene

position:313016:-1
position: 313016
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:313915:-1
position: 313915
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:313016-313915:-1:exon

YJL068C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJL068C
product: S-formylglutathione hydrolase
transcript id: NM_001181501.1
SIO_010081: YJL068C
subclass of: SO_0000673
so part of: YJL068C
location: complement(<313016..>313915)
location: region:313016-313915:-1
so has part: feature:313016-313915:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:313016-313915:-1:exon

YJL068C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJL068C
EC number: 3.1.2.12
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:10427036]
experiment: EXISTENCE:direct assay:GO:0018738 S-formylglutathione hydrolase activity [PMID:10427036]
experiment: EXISTENCE:mutant phenotype:GO:0046294 formaldehyde catabolic process [PMID:10427036]
note: Esterase that can function as an S-formylglutathione hydrolase; non-essential intracellular esterase; may be involved in the detoxification of formaldehyde, which can be metabolized to S-formylglutathione; similar to human esterase D
codon start: 1
product: S-formylglutathione hydrolase
translation: MKVVKEFSVCGGRLIKLSHNSNSTKTSMNVNIYLPKHYYAQDFPRNKRIPTVFYLSGLTCTPDNASEKAFWQFQADKYGFAIVFPDTSPRGDEVANDPEGSWDFGQGAGFYLNATQEPYAQHYQMYDYIHKELPQTLDSHFNKNGDVKLDFLDNVAITGHSMGGYGAICGYLKGYSGKRYKSCSAFAPIVNPSNVPWGQKAFKGYLGEEKAQWEAYDPCLLIKNIRHVGDDRILIHVGDSDPFLEEHLKPELLLEAVKATSWQDYVEIKKVHGFDHSYYFVSTFVPEHAEFHARNLGLI
SIO_010081: YJL068C
subclass of: SO_0000673
so part of: YJL068C
location: complement(313016..313915)
location: region:313016-313915:-1
so has part: feature:313016-313915:-1:exon

NP_012467.1
type: Protein
SIO_000068: ncbiprotein

S000003604
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:313016-313915:-1:exon

YJL066C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MPM1
locus tag: YJL066C
so part of: sequence
location: complement(<314114..>314872)
location: region:314114-314872:-1
so has part: feature:314114-314872:-1:exon
subclass of: SO_0000010

853379
type: Gene
SIO_000068: ncbigene

position:314114:-1
position: 314114
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:314872:-1
position: 314872
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:314114-314872:-1:exon

YJL066C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MPM1
locus tag: YJL066C
product: Mpm1p
transcript id: NM_001181499.3
SIO_010081: YJL066C
subclass of: SO_0000673
so part of: YJL066C
location: complement(<314114..>314872)
location: region:314114-314872:-1
so has part: feature:314114-314872:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:314114-314872:-1:exon

YJL066C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MPM1
locus tag: YJL066C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:11791739|PMID:9874242|PMID:14576278|PMID:16823961|PM ID:24769239]
experiment: EXISTENCE:direct assay:GO:0005758 mitochondrial intermembrane space [PMID:22984289|PMID:22993211]
note: Mitochondrial intermembrane space hypothetical protein
codon start: 1
product: Mpm1p
translation: MGFYEGDDNDANTKAFNDKYIKDQKFATAPFWNLFPKLRDIDEYDNPLLPLPFNFNFRDLGDSALAMASGIPTVKQFDKCEELKGQSAWTTQGIWKCLVPSKAIPPLPQLDFLLPLEEIKSDKSHSHGLFFNDFNLFLKWRSHMNRLQKQRIKTRSTAVEPLARTPEDLMLNWDDLHLGNDAEYASADGSKKIVGRAQSISTTKDSNDAKPSTVKTEKIYFDDGTVDITTTTTSKGSSPQVKHKVVSVDEDN
SIO_010081: YJL066C
subclass of: SO_0000673
so part of: YJL066C
location: complement(314114..314872)
location: region:314114-314872:-1
so has part: feature:314114-314872:-1:exon

NP_012469.3
type: Protein
SIO_000068: ncbiprotein

S000003602
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:314114-314872:-1:exon

YJL065C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: DLS1
locus tag: YJL065C
so part of: sequence
location: complement(<315054..>315557)
location: region:315054-315557:-1
so has part: feature:315054-315557:-1:exon
subclass of: SO_0000010

853381
type: Gene
SIO_000068: ncbigene

position:315054:-1
position: 315054
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:315557:-1
position: 315557
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:315054-315557:-1:exon

YJL065C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: DLS1
locus tag: YJL065C
product: Dls1p
transcript id: NM_001181498.1
SIO_010081: YJL065C
subclass of: SO_0000673
so part of: YJL065C
location: complement(<315054..>315557)
location: region:315054-315557:-1
so has part: feature:315054-315557:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:315054-315557:-1:exon

YJL065C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: DLS1
locus tag: YJL065C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0008623 CHRAC [PMID:15024052]
experiment: EXISTENCE:mutant phenotype:GO:0031509 subtelomeric heterochromatin formation [PMID:14673157]
note: Subunit of ISW2/yCHRAC chromatin accessibility complex; ISW2/yCHRAC also includes Itc1p, Isw2p, and Dpb4p; involved in inheritance of telomeric silencing; DLS1 has a paralog, DPB3, that arose from the whole genome duplication
codon start: 1
product: Dls1p
translation: MNNETSGKETASAPLCSPKLPVEKVQRIAKNDPEYMDTSDDAFVATAFATEFFVQVLTHESLHRQQQQQQQQVPPLPDELTLSYDDISAAIVHSSDGHLQFLNDVIPTTKNLRLLVEENRVRYTTSVMPPNEVYSAYVVNDTAPKPNIVEIDLDNDEDDDEDVTDQE
SIO_010081: YJL065C
subclass of: SO_0000673
so part of: YJL065C
location: complement(315054..315557)
location: region:315054-315557:-1
so has part: feature:315054-315557:-1:exon

NP_012470.1
type: Protein
SIO_000068: ncbiprotein

S000003601
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:315054-315557:-1:exon

YJL063C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: bL17m
alternative label: HRD238
gene: MRPL8
locus tag: YJL063C
gene synonym: bL17m; HRD238
so part of: sequence
location: complement(<315759..>316475)
location: region:315759-316475:-1
so has part: feature:315759-316475:-1:exon
subclass of: SO_0000010

853382
type: Gene
SIO_000068: ncbigene

position:315759:-1
position: 315759
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:316475:-1
position: 316475
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:315759-316475:-1:exon

YJL063C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: bL17m
alternative label: HRD238
gene: MRPL8
locus tag: YJL063C
gene synonym: bL17m; HRD238
product: mitochondrial 54S ribosomal protein YmL8
transcript id: NM_001181496.1
SIO_010081: YJL063C
subclass of: SO_0000673
so part of: YJL063C
location: complement(<315759..>316475)
location: region:315759-316475:-1
so has part: feature:315759-316475:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:315759-316475:-1:exon

YJL063C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: bL17m
alternative label: HRD238
gene: MRPL8
locus tag: YJL063C
gene synonym: bL17m; HRD238
experiment: EXISTENCE:curator inference:GO:0032543 mitochondrial translation [PMID:12392552]
experiment: EXISTENCE:direct assay:GO:0003735 structural constituent of ribosome [PMID:12392552]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005762 mitochondrial large ribosomal subunit [PMID:12392552]
note: Mitochondrial ribosomal protein of the large subunit
codon start: 1
product: mitochondrial 54S ribosomal protein YmL8
translation: MTVGIARKLSRDKAHRDALLKNLACQLFQHESIVSTHAKCKEASRVAERIITWTKRAITTSNSVAQAELKSQIQSQLFLAGDNRKLMKRLFSEIAPRYLERPGGYTRVLRLEPRANDSAPQSVLELVDSPVMSESHTVNRGNLKMWLLVKSVINDDANQLPHNPLTLQNLHKVAKFKAEAQLHGEIMLIKQVLLKEMSLPYDEALENERTQALLKEVYSSSLPKKTKKPSSYVMVPRP
SIO_010081: YJL063C
subclass of: SO_0000673
so part of: YJL063C
location: complement(315759..316475)
location: region:315759-316475:-1
so has part: feature:315759-316475:-1:exon

NP_012472.1
type: Protein
SIO_000068: ncbiprotein

S000003599
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:315759-316475:-1:exon

YJL062W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: COX25
alternative label: RRG10
gene: COA3
locus tag: YJL062W-A
gene synonym: COX25; RRG10
so part of: sequence
location: <316723..>316980
location: region:316723-316980:1
so has part: feature:316723-316980:1:exon
subclass of: SO_0000010

853383
type: Gene
SIO_000068: ncbigene

position:316723:1
position: 316723
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:316980:1
position: 316980
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:316723-316980:1:exon

YJL062W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: COX25
alternative label: RRG10
gene: COA3
locus tag: YJL062W-A
gene synonym: COX25; RRG10
product: Coa3p
transcript id: NM_001184477.3
SIO_010081: YJL062W-A
subclass of: SO_0000673
so part of: YJL062W-A
location: <316723..>316980
location: region:316723-316980:1
so has part: feature:316723-316980:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:316723-316980:1:exon

YJL062W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: COX25
alternative label: RRG10
gene: COA3
locus tag: YJL062W-A
gene synonym: COX25; RRG10
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005743 mitochondrial inner membrane [PMID:21068384|PMID:20876281]
experiment: EXISTENCE:mutant phenotype:GO:0033617 mitochondrial cytochrome c oxidase assembly [PMID:21068384|PMID:20876281]
experiment: EXISTENCE:mutant phenotype:GO:0070130 negative regulation of mitochondrial translation [PMID:21068384|PMID:20876281]
note: Mitochondrial protein required for cytochrome c oxidase assembly; also involved in translational regulation of Cox1p and prevention of Cox1p aggregation before assembly; located in the mitochondrial inner membrane
codon start: 1
product: Coa3p
translation: MVLNPSKYQDTRTWKMTPAMIRARKPFFKGNMLGLTLLLGVTGSVYYYTYHFLHKDNDFADVPIPPIDPQELEALKKEYEAKKKA
SIO_010081: YJL062W-A
subclass of: SO_0000673
so part of: YJL062W-A
location: 316723..316980
location: region:316723-316980:1
so has part: feature:316723-316980:1:exon

NP_076894.3
type: Protein
SIO_000068: ncbiprotein

S000007611
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:316723-316980:1:exon

YJL062W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: GPI7
gene: LAS21
locus tag: YJL062W
gene synonym: GPI7
so part of: sequence
location: <317284..>319776
location: region:317284-319776:1
so has part: feature:317284-319776:1:exon
subclass of: SO_0000010

853384
type: Gene
SIO_000068: ncbigene

position:317284:1
position: 317284
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:319776:1
position: 319776
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:317284-319776:1:exon

YJL062W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: GPI7
gene: LAS21
locus tag: YJL062W
gene synonym: GPI7
product: mannose-ethanolamine phosphotransferase LAS21
transcript id: NM_001181495.1
SIO_010081: YJL062W
subclass of: SO_0000673
so part of: YJL062W
location: <317284..>319776
location: region:317284-319776:1
so has part: feature:317284-319776:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:317284-319776:1:exon

YJL062W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: GPI7
gene: LAS21
locus tag: YJL062W
gene synonym: GPI7
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:10329735]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:10329735]
experiment: EXISTENCE:mutant phenotype:GO:0006506 GPI anchor biosynthetic process [PMID:15452134|PMID:10329735]
experiment: EXISTENCE:mutant phenotype:GO:0051267 CP2 mannose-ethanolamine phosphotransferase activity [PMID:10329735|PMID:15452134]
note: Mannose-ethanolamine phosphotransferase; involved in biosynthesis of the glycosylphosphatidylinositol (GPI) core structure, catalyzing the addition of a side chain ethanolamine phosphate to the alpha1,6-linked second mannose residue of the GPI lipid precursor; integral component of endoplasmic reticulum membrane; mutations affect cell wall integrity; homolog of human PIGG
codon start: 1
product: mannose-ethanolamine phosphotransferase LAS21
translation: MNLKQFTCLSCAQLLAILLFIFAFFPRKIVLTGISKQDPDQDRDLQRDRPFQKLVFVIIDALRSDFLFDSQISHFNNVHQWLNTGEAWGYTSFANPPTVTLPRLKSITTGSTPSFIDLLLNVAQDIDSNDLSEHDSWLQQFIQHNNTIRFMGDDTWLKLFPQQWFDFADPTHSFFVSDFTQVDNNVTRNLPGKLFQEWAQWDVAILHYLGLDHIGHKDGPHSKFMAAKHQEMDSILKSIYDEVLEHEDDDDTLICVLGDHGMNELGNHGGSSAGETSAGLLFLSPKLAQFARPESQVNYTLPINASPDWNFQYLETVQQIDIVPTIAALFGMPIPMNSVGIIIPDFLQLLPNKLASMKENFMHLWKLSDHHGEVALDDFTAEDIYTKMYTIQETLTKSATNYNYPLLTLAFVGFLIITIIAIYVLLRYSGPDFWQLRVSSLSVLLVSIILGVSTFASSFIEEEHQLWWWIVTAFSAVPLFVYRLNVLIIVRWFIMMACVRSIKFWNNSGQKFIYSNVMSNLLNQNPSWKWCLNMLTFLVLIMASAGFQVLHFIVTTILVGLCFTYKISWEIVNGNQAEIPLFMHDLLAKIDFAPTESNLIVLARVFFQAWAIVVISRLVLTKLKVLNKNYLIKDMKVYITILLMFQTSSQNIGQFLVFQILESQIFYFFQNIPTASLTSTSKIYFSNLVSLILQNFTFFQFGGTNSISTIDLGNAYHGVSSDYNIYVVGILMSVANFAPAIYWSMLPWSINYASIPAQVKLQTFIRSKLPAFTYHCIFGTCLMTACVVLRFHLFIWSVFSPKLCYFLGWNFVMGLLNGWLPELALLCALD
SIO_010081: YJL062W
subclass of: SO_0000673
so part of: YJL062W
location: 317284..319776
location: region:317284-319776:1
so has part: feature:317284-319776:1:exon

NP_012473.1
type: Protein
SIO_000068: ncbiprotein

S000003598
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:317284-319776:1:exon

YJL061W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: HRB187
gene: NUP82
locus tag: YJL061W
gene synonym: HRB187
so part of: sequence
location: <320016..>322157
location: region:320016-322157:1
so has part: feature:320016-322157:1:exon
subclass of: SO_0000010

853385
type: Gene
SIO_000068: ncbigene

position:320016:1
position: 320016
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:322157:1
position: 322157
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:320016-322157:1:exon

YJL061W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: HRB187
gene: NUP82
locus tag: YJL061W
gene synonym: HRB187
product: linker nucleoporin NUP82
transcript id: NM_001181494.1
SIO_010081: YJL061W
subclass of: SO_0000673
so part of: YJL061W
location: <320016..>322157
location: region:320016-322157:1
so has part: feature:320016-322157:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:320016-322157:1:exon

YJL061W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: HRB187
gene: NUP82
locus tag: YJL061W
gene synonym: HRB187
experiment: EXISTENCE:curator inference:GO:0017056 structural constituent of nuclear pore [PMID:18046406]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0005643 nuclear pore [PMID:10684247|PMID:7559751]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0044612 nuclear pore linkers [PMID:18046406]
experiment: EXISTENCE:direct assay:GO:0044614 nuclear pore cytoplasmic filaments [PMID:10684247|PMID:9736720]
experiment: EXISTENCE:mutant phenotype:GO:0000055 ribosomal large subunit export from nucleus [PMID:11071906|PMID:11739405]
experiment: EXISTENCE:mutant phenotype:GO:0000056 ribosomal small subunit export from nucleus [PMID:10465789|PMID:11739405]
experiment: EXISTENCE:mutant phenotype:GO:0006406 mRNA export from nucleus [PMID:7559750|PMID:7559751]
experiment: EXISTENCE:mutant phenotype:GO:0006606 protein import into nucleus [PMID:15294903]
experiment: EXISTENCE:mutant phenotype:GO:0006611 protein export from nucleus [PMID:15294903|PMID:17347149]
note: Linker nucleoporin component of the nuclear pore complex (NPC); also part of the NPC cytoplasmic filaments; contributes to nucleocytoplasmic transport and NPC biogenesis; forms stable associations with three FG-nucleoporins (Nsp1p, Nup159p, and Nup116p); relocalizes to the cytosol in response to hypoxia
codon start: 1
product: linker nucleoporin NUP82
translation: MSQSSRLSALPIFQASLSASQSPRYIFSSQNGTRIVFIQDNIIRWYNVLTDSLYHSLNFSRHLVLDDTFHVISSTSGDLLCLFNDNEIFVMEVPWGYSNVEDVSIQDAFQIFHYSIDEEEVGPKSSIKKVLFHPKSYRDSCIVVLKEDDTITMFDILNSQEKPIVLNKPNNSFGLDARVNDITDLEFSKDGLTLYCLNTTEGGDIFAFYPFLPSVLLLNEKDLNLILNKSLVMYESLDSTTDVIVKRNVIKQLQFVSKLHENWNSRFGKVDIQKEYRLAKVQGPFTINPFPGELYDYTATNIATILIDNGQNEIVCVSFDDGSLILLFKDLEMSMSWDVDNYVYNNSLVLIERVKLQREIKSLITLPEQLGKLYVISDNIIQQVNFMSWASTLSKCINESDLNPLAGLKFESKLEDIATIERIPNLAYINWNDQSNLALMSNKTLTFQNISSDMKPQSTAAETSISTEKSDTVGDGFKMSFTQPINEILILNDNFQKACISPCERIIPSADRQIPLKNEASENQLEIFTDISKEFLQRIVKAQTLGVSIHNRIHEQQFELTRQLQSTCKIISKDDDLRRKFEAQNKKWDAQLSRQSELMERFSKLSKKLSQIAESNKFKEKKISHGEMKWFKEIRNQILQFNSFVHSQKSLQQDLSYLKSELTRIEAETIKVDKKSQNEWDELRKMLEIDSKIIKECNEELLQVSQEFTTKTQ
SIO_010081: YJL061W
subclass of: SO_0000673
so part of: YJL061W
location: 320016..322157
location: region:320016-322157:1
so has part: feature:320016-322157:1:exon

NP_012474.1
type: Protein
SIO_000068: ncbiprotein

S000003597
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:320016-322157:1:exon

YJL060W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: BNA3
locus tag: YJL060W
so part of: sequence
location: <323386..>324720
location: region:323386-324720:1
so has part: feature:323386-324720:1:exon
subclass of: SO_0000010

853386
type: Gene
SIO_000068: ncbigene

position:323386:1
position: 323386
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:324720:1
position: 324720
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:323386-324720:1:exon

YJL060W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: BNA3
locus tag: YJL060W
product: kynurenine--oxoglutarate transaminase
transcript id: NM_001181493.3
SIO_010081: YJL060W
subclass of: SO_0000673
so part of: YJL060W
location: <323386..>324720
location: region:323386-324720:1
so has part: feature:323386-324720:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:323386-324720:1:exon

YJL060W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: BNA3
locus tag: YJL060W
EC number: 2.6.1.7
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:17034789|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:17034789|PMID:14562095|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0016212 kynurenine-oxoglutarate transaminase activity [PMID:18205391]
experiment: EXISTENCE:direct assay:GO:0034276 kynurenic acid biosynthetic process [PMID:18205391]
experiment: EXISTENCE:direct assay:GO:0047536 2-aminoadipate transaminase activity [PMID:19342587]
note: Kynurenine aminotransferase; catalyzes formation of kynurenic acid from kynurenine; potential Cdc28p substrate
codon start: 1
product: kynurenine--oxoglutarate transaminase
translation: MKQRFIRQFTNLMSTSRPKVVANKYFTSNTAKDVWSLTNEAAAKAANNSKNQGRELINLGQGFFSYSPPQFAIKEAQKALDIPMVNQYSPTRGRPSLINSLIKLYSPIYNTELKAENVTVTTGANEGILSCLMGLLNAGDEVIVFEPFFDQYIPNIELCGGKVVYVPINPPKELDQRNTRGEEWTIDFEQFEKAITSKTKAVIINTPHNPIGKVFTREELTTLGNICVKHNVVIISDEVYEHLYFTDSFTRIATLSPEIGQLTLTVGSAGKSFAATGWRIGWVLSLNAELLSYAAKAHTRICFASPSPLQEACANSINDALKIGYFEKMRQEYINKFKIFTSIFDELGLPYTAPEGTYFVLVDFSKVKIPEDYPYPEEILNKGKDFRISHWLINELGVVAIPPTEFYIKEHEKAAENLLRFAVCKDDAYLENAVERLKLLKDYL
SIO_010081: YJL060W
subclass of: SO_0000673
so part of: YJL060W
location: 323386..324720
location: region:323386-324720:1
so has part: feature:323386-324720:1:exon

NP_012475.3
type: Protein
SIO_000068: ncbiprotein

S000003596
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:323386-324720:1:exon

YJL059W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: BTN1
gene: YHC3
locus tag: YJL059W
gene synonym: BTN1
so part of: sequence
location: <324964..>326190
location: region:324964-326190:1
so has part: feature:324964-326190:1:exon
subclass of: SO_0000010

853387
type: Gene
SIO_000068: ncbigene

position:324964:1
position: 324964
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:326190:1
position: 326190
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:324964-326190:1:exon

YJL059W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: BTN1
gene: YHC3
locus tag: YJL059W
gene synonym: BTN1
product: amino acid transporter YHC3
transcript id: NM_001181492.1
SIO_010081: YJL059W
subclass of: SO_0000673
so part of: YJL059W
location: <324964..>326190
location: region:324964-326190:1
so has part: feature:324964-326190:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:324964-326190:1:exon

YJL059W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: BTN1
gene: YHC3
locus tag: YJL059W
gene synonym: BTN1
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:10319861|PMID:9753630]
experiment: EXISTENCE:mutant phenotype:GO:0015819 lysine transport [PMID:14660799]
experiment: EXISTENCE:mutant phenotype:GO:0051453 regulation of intracellular pH [PMID:10191121|PMID:10319861|PMID:16423829]
experiment: EXISTENCE:mutant phenotype:GO:1903826 L-arginine transmembrane transport [PMID:14660799]
note: Protein required for the ATP-dependent transport of arginine; vacuolar membrane protein; involved in the ATP-dependent transport of arginine into the vacuole and possibly in balancing ion homeostasis; human homolog CLN3 involved in Batten disease (juvenile onset neuronal ceroid lipofuscinosis) can complement yeast null mutant
codon start: 1
product: amino acid transporter YHC3
translation: MSDKSHQIYCYFWLFGLINNVLYVVILSAAVDIVGPTLPKSLVLLADIFPSLAIKLCSPFFIDRIKYSYRIWSLITMSCLGMFLVSFKNLFVCLLGISFASISSGFGEVTFLQLTHYYKQISLNGWSSGTGGAGIIGGASYMFLTSIFKVPVKLTLLVFSLLPFAFLFYFKLESNDTNLTYQSLQQIDEAEDDQLVPFPVAFTHTNASQSLYSTRQHILQTVKRLRRLVFPYMVPLTTVYLFEYLINQAVAPTLLFPINGDERSKSMPFFFHKYRDIYVTYGTLYQLGVFISRSFGHLMRMRSLYILAFLQGVNLCITVLQSWFYVTHSPWAVMILIFYEGFLGGASYVNTFLNILEQEDPDETEFAMGAVSIADSFGVFLAALLGLGLEPKLCRHQIADDRPWCRME
SIO_010081: YJL059W
subclass of: SO_0000673
so part of: YJL059W
location: 324964..326190
location: region:324964-326190:1
so has part: feature:324964-326190:1:exon

NP_012476.1
type: Protein
SIO_000068: ncbiprotein

S000003595
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:324964-326190:1:exon

YJL058C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: BIT61
locus tag: YJL058C
so part of: sequence
location: complement(<326242..>327873)
location: region:326242-327873:-1
so has part: feature:326242-327873:-1:exon
subclass of: SO_0000010

853388
type: Gene
SIO_000068: ncbigene

position:326242:-1
position: 326242
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:327873:-1
position: 327873
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:326242-327873:-1:exon

YJL058C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: BIT61
locus tag: YJL058C
product: Bit61p
transcript id: NM_001181491.1
SIO_010081: YJL058C
subclass of: SO_0000673
so part of: YJL058C
location: complement(<326242..>327873)
location: region:326242-327873:-1
so has part: feature:326242-327873:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:326242-327873:-1:exon

YJL058C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: BIT61
locus tag: YJL058C
experiment: EXISTENCE:curator inference:GO:0038203 TORC2 signaling [PMID:14736892]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:19144819]
experiment: EXISTENCE:direct assay:GO:0031932 TORC2 complex [PMID:14736892]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:physical interaction:GO:0001558 regulation of cell growth [PMID:14736892]
experiment: EXISTENCE:physical interaction:GO:0030950 establishment or maintenance of actin cytoskeleton polarity [PMID:14736892]
experiment: EXISTENCE:physical interaction:GO:0031505 fungal-type cell wall organization [PMID:14736892]
note: Subunit of TORC2, a regulator of plasma membrane (PM) homeostasis; TORC2 also regulates actin cytoskeletal dynamics during polarized growth and cell wall integrity; interacts with Slm1p and Slm2p, homologous PH domain-containing TORC2 substrates; PM retention is dependent on Avo3p; BIT61 has a paralog, BIT2, that arose from the whole genome duplication
codon start: 1
product: Bit61p
translation: MTAEDILLRERTSTTTQRPVNSEQYLNVQLATAPVKNFQTTSEISRQTLVDTSNDDVYSIKNLKGSRNPISPSVSNVGFQSIFHTVDHPRSKVSVASNHSLRSNDNASAATSKSGSSQIGESHSVDTVECSNNLSKKLSSDAISITQKSLHSTPSGRYMKGKASGFFNRRNRAHTTISSDPASFLTDSSTLHNSSHSFRNVIKNFFQNKSHRHIGQDAIEPAIPNSLSKFLHSSYGRHKSPSQFIHTNAGQLVDSGTSVYSLNVNPSGVNPNTIVEDPLSGTDPASPNPVSMLHDLLRNLPSLEANYKHFNSQELTTLTNNIWNIFCSNVAELFRTQRIWKLRAKIENFNEVLEFYCILKTDPRVTHSGMNRIISDLKEFLVSSLYNLENQIVFNYSNEDTINNALKRLGVIWRIFYQEVYYDLAAVLLPLDQSIREDGNSTVLKSGNESRTHINGNYSIGFLLLMCFRDSIVLPCYENFVNSNDGISKSFQLYIFNQEEESNVTETDKLTLLQCFGILSTIQSNDRNQRIIEELLAGIRMSI
SIO_010081: YJL058C
subclass of: SO_0000673
so part of: YJL058C
location: complement(326242..327873)
location: region:326242-327873:-1
so has part: feature:326242-327873:-1:exon

NP_012477.1
type: Protein
SIO_000068: ncbiprotein

S000003594
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:326242-327873:-1:exon

YJL057C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: IKS1
locus tag: YJL057C
so part of: sequence
location: complement(<328118..>330121)
location: region:328118-330121:-1
so has part: feature:328118-330121:-1:exon
subclass of: SO_0000010

853389
type: Gene
SIO_000068: ncbigene

position:328118:-1
position: 328118
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:330121:-1
position: 330121
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:328118-330121:-1:exon

YJL057C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: IKS1
locus tag: YJL057C
product: protein kinase IKS1
transcript id: NM_001181490.3
SIO_010081: YJL057C
subclass of: SO_0000673
so part of: YJL057C
location: complement(<328118..>330121)
location: region:328118-330121:-1
so has part: feature:328118-330121:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:328118-330121:-1:exon

YJL057C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: IKS1
locus tag: YJL057C
EC number: 2.7.11.1
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:16319894]
experiment: EXISTENCE:direct assay:GO:0006468 protein phosphorylation [PMID:16319894]
note: Protein kinase of unknown cellular role; putative serine/threonine kinase; expression is induced during mild heat stress; deletion mutants are hypersensitive to copper sulphate and resistant to sorbate; interacts with an N-terminal fragment of Sst2p
codon start: 1
product: protein kinase IKS1
translation: MSLVPYEEGSLILDDPNSKSVVVVNPTSGTLSFFQQDNSNNDSELNEDQTASLSALDFPSGIHQYKSPIASYVCPQCGTEINPDIINRRQLHRRASAGVESESSRLSIPENTVPLGFEFANSSFSRRYFQSLERNHRHYALQNDSNNKQGQFSKNKYFIPDDLFIPGYFRKFFKILSLLGNGARGSVYKVVHTIGNTELGVFALKKIPIGNDMEWFNKCIREVKALSSLTHKSANLITYNHVWLEMDSSVGFVRSIDGSQSDSQEEVPCIFILQQYCSGGNLEDCILRKVFNRFSDTESPEERKKKFRTRKKNHGKSGEVGLSTEQLVSIIRDIARGLHELHSIGLIHRDLKPSNCLLLTPFKSDNENDNVYDREHNSDEFFPSIVIGDLGESQLEGESRLGTGCTGTLEFTAPDLIIQGRPVSSSTLPSRSSHTYNEYTFASDMYSLGMICYFIVFGELPFEPQLDIVDLKVRIKNFRFDTEGMIEKHQAMKLKPIDRRIFHLMDALLQPNNDARPTAKTVEETLDEMLINSKPGKKFWKENVDSTLNFSTISEVNENTNSFTDDYIDGDNVTLSLPAPEENLSTVSTQNLQKYSALNRTIQVCYKLVSMILTIIIFKCTKTGSWLSYMSLILLGMVFKSPADERGKHARALVLLAFIAACKKYIY
SIO_010081: YJL057C
subclass of: SO_0000673
so part of: YJL057C
location: complement(328118..330121)
location: region:328118-330121:-1
so has part: feature:328118-330121:-1:exon

NP_012478.3
type: Protein
SIO_000068: ncbiprotein

S000003593
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:328118-330121:-1:exon

YJL056C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ZRG10
gene: ZAP1
locus tag: YJL056C
gene synonym: ZRG10
so part of: sequence
location: complement(<330431..>333073)
location: region:330431-333073:-1
so has part: feature:330431-333073:-1:exon
subclass of: SO_0000010

853390
type: Gene
SIO_000068: ncbigene

position:330431:-1
position: 330431
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:333073:-1
position: 333073
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:330431-333073:-1:exon

YJL056C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ZRG10
gene: ZAP1
locus tag: YJL056C
gene synonym: ZRG10
product: Zap1p
transcript id: NM_001181489.1
SIO_010081: YJL056C
subclass of: SO_0000673
so part of: YJL056C
location: complement(<330431..>333073)
location: region:330431-333073:-1
so has part: feature:330431-333073:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:330431-333073:-1:exon

YJL056C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ZRG10
gene: ZAP1
locus tag: YJL056C
gene synonym: ZRG10
experiment: EXISTENCE:direct assay:GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding [PMID:9786867]
experiment: EXISTENCE:direct assay:GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific [PMID:22128164]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:10899124]
experiment: EXISTENCE:direct assay:GO:0008270 zinc ion binding [PMID:14517251|PMID:16720702]
experiment: EXISTENCE:direct assay:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:22128164]
experiment: EXISTENCE:mutant phenotype:GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding [PMID:9786867|PMID:12549926]
experiment: EXISTENCE:mutant phenotype:GO:0006357 regulation of transcription by RNA polymerase II [PMID:9271382|PMID:9786867]
experiment: EXISTENCE:mutant phenotype:GO:0008270 zinc ion binding [PMID:16720702]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:12095998]
note: Zinc-regulated transcription factor; binds to zinc-responsive promoters to induce transcription of certain genes in presence of zinc, represses other genes in low zinc; regulates its own transcription; contains seven zinc-finger domains
codon start: 1
product: Zap1p
translation: MDALTPRDSPKRDDSMATSAATAASAKPDALTIGKEGIVHGHIHNYNNLTYIHGHLHHSAPVNDSSASATPAAAAVADAATSAFASGASHDMGGDCHVNEKCKEYTDCQHFEFLNYHNNPSLTKYNDTATYNSNNHSFANNFHSVASDPTSPQQNSKSDLPRRKDSWFNDDLILLPSSKKNKPNPPPGSDDCYCTPKILEICCDETHPKSEANIKQGESDQPTKKDISENGNDVAIFTDVKNDHLMPNFNLHDQYCNSTNHDSHNHNNTVPDSFSQLMSHLSEIDCDLTCDTPCTASTSATSGHKFVQDHQSSNNDDVFHKYCKFCEESTDNQPCSKHMHLESKPPQLPPKCSSLRKPTNTLQGTNHAYHEHILNTDMDLKILEDLCNISSLYEVPFGKHINHHDHNNAGNGCDGSSTGNNENGNQTMNLLLSSINRCNPKNNLNGSNNNTAGATSTDHQHHHHRIQFHSHKPNRNNIVNNSGISAANTTADLTNNDLNDLISREYSYERFRNQSEPPSLPKVTHQNQKNRRSWPTKDLESTDFSSLEDSLPSSISPPIQTTSTINFNWCFKEEKNNDLKCKWKECPESCSSLFDLQRHLLKDHVSQDFKHPMEPLACNWEDCDFLGDDTCSIVNHINCQHGINFDIQFANPDSFLPGSISKEKHHLLHCPNPQTHEVSKADGAPDMTSANDVSNIPPIKQPEQVICQWDGCNKSFSSAQELNDHLEAVHLTRGKSEYQCLWHDCHRTFPQRQKLIRHLKVHSKYKPYKCKTCKRCFSSEETLVQHTRTHSGEKPYKCHICNKKFAISSSLKIHIRTHTGEKPLQCKICGKRFNESSNLSKHIKTHQKKYKCSDCSKSFDDLGKLNSQKVKCALERKPYL
SIO_010081: YJL056C
subclass of: SO_0000673
so part of: YJL056C
location: complement(330431..333073)
location: region:330431-333073:-1
so has part: feature:330431-333073:-1:exon

NP_012479.1
type: Protein
SIO_000068: ncbiprotein

S000003592
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:330431-333073:-1:exon

YJL055W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: LOG1
locus tag: YJL055W
so part of: sequence
location: <333357..>334094
location: region:333357-334094:1
so has part: feature:333357-334094:1:exon
subclass of: SO_0000010

853391
type: Gene
SIO_000068: ncbigene

position:333357:1
position: 333357
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:334094:1
position: 334094
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:333357-334094:1:exon

YJL055W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: LOG1
locus tag: YJL055W
product: Log1p
transcript id: NM_001181488.1
SIO_010081: YJL055W
subclass of: SO_0000673
so part of: YJL055W
location: <333357..>334094
location: region:333357-334094:1
so has part: feature:333357-334094:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:333357-334094:1:exon

YJL055W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: LOG1
locus tag: YJL055W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0014074 response to purine-containing compound [PMID:15932646]
note: hypothetical protein; functions together with HAM1 to mediate resistance to 5-FU; specifically reduces the incorporation of 5-FU into RNA, without affecting uptake or incorporation of uracil into RNA; proposed to be involved in the metabolism of purine and pyrimidine base analogues; deletion mutants are sensitive to HAP and AHA
codon start: 1
product: Log1p
translation: MTMEKNGGNSSRGGQVGGKSVCVYCGSSFGAKALYSESAEELGALFHKLGWKLVYGGGTTGLMGKIARSTMGPDLSGQVHGIIPNALVSKERTDEDKEDVNKALLESVENHKGATPISEEYGETTIVPDMHTRKRMMANLSDAFVAMPGGYGTFEEIMECITWSQLGIHNKPIILFNIDGFYDKLLEFLKHSIQERFISVKNGEIIQVASTPQEVVDKIEKYVVPEGRFNLNWSDEGHAHEDCAK
SIO_010081: YJL055W
subclass of: SO_0000673
so part of: YJL055W
location: 333357..334094
location: region:333357-334094:1
so has part: feature:333357-334094:1:exon

NP_012480.1
type: Protein
SIO_000068: ncbiprotein

S000003591
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:333357-334094:1:exon

YJL054W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TIM54
locus tag: YJL054W
so part of: sequence
location: <334265..>335701
location: region:334265-335701:1
so has part: feature:334265-335701:1:exon
subclass of: SO_0000010

853392
type: Gene
SIO_000068: ncbigene

position:334265:1
position: 334265
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:335701:1
position: 335701
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:334265-335701:1:exon

YJL054W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TIM54
locus tag: YJL054W
product: Tim54p
transcript id: NM_001181487.3
SIO_010081: YJL054W
subclass of: SO_0000673
so part of: YJL054W
location: <334265..>335701
location: region:334265-335701:1
so has part: feature:334265-335701:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:334265-335701:1:exon

YJL054W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TIM54
locus tag: YJL054W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0008320 protein transmembrane transporter activity [PMID:12637749]
experiment: EXISTENCE:direct assay:GO:0042721 TIM22 mitochondrial import inner membrane insertion complex [PMID:10648604|PMID:10637294]
experiment: EXISTENCE:genetic interaction:GO:0045039 protein insertion into mitochondrial inner membrane [PMID:10637294|PMID:9412462]
experiment: EXISTENCE:mutant phenotype:GO:0045039 protein insertion into mitochondrial inner membrane [PMID:17893242|PMID:9412462]
note: Component of the mitochondrial TIM22 complex; involved in insertion of polytopic proteins into the inner membrane
codon start: 1
product: Tim54p
translation: MSSESGKPIAKPIRKPGYTNPALKALGIPALRLPSRNWMIFWSVLTVSIGGIAYDKYKQRQILSHATDLVKPLAEESMEVDKVPRKITVFIAPPPNDYLESSLKVWRRYVKPVLYYAGLDYELVQEDRQGIIRTNVANRIRELRKEILASTDGQPVKEPNQTVAKPSGSSTSKISSLLPFNKIIQDPAEEDDSFDPEIGKKFKENFDWRNVIGIFYTMPKPKHIISEDALTKDPILSGGVICLGRGAYKEYIAGIHEGLLGPIEKTEKTGSTEPKMTGVVEANQIESKVSESGATELVDAEKETALEEAKVQDDLKVDEENSSEDSQKFLKPFISSDQYPDLQIASELQTPNGEFIRNPNTNIPLLINQPLLVIPIPNLIGFTTIPRRIHRFYQKRFYVEDVCSSVVNCVRQTRIRPFDIAKDIDLAKDEEKDWPQNWVKQGKEKNSEWTQELVCDPRITKHMFVYEKPPKEEPESDI
SIO_010081: YJL054W
subclass of: SO_0000673
so part of: YJL054W
location: 334265..335701
location: region:334265-335701:1
so has part: feature:334265-335701:1:exon

NP_012481.3
type: Protein
SIO_000068: ncbiprotein

S000003590
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:334265-335701:1:exon

YJL053W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: GRD6
alternative label: VPS26
alternative label: VPT4
gene: PEP8
locus tag: YJL053W
gene synonym: GRD6; VPS26; VPT4
so part of: sequence
location: <335898..>337037
location: region:335898-337037:1
so has part: feature:335898-337037:1:exon
subclass of: SO_0000010

853393
type: Gene
SIO_000068: ncbigene

position:335898:1
position: 335898
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:337037:1
position: 337037
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:335898-337037:1:exon

YJL053W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: GRD6
alternative label: VPS26
alternative label: VPT4
gene: PEP8
locus tag: YJL053W
gene synonym: GRD6; VPS26; VPT4
product: retromer subunit PEP8
transcript id: NM_001181486.1
SIO_010081: YJL053W
subclass of: SO_0000673
so part of: YJL053W
location: <335898..>337037
location: region:335898-337037:1
so has part: feature:335898-337037:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:335898-337037:1:exon

YJL053W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: GRD6
alternative label: VPS26
alternative label: VPT4
gene: PEP8
locus tag: YJL053W
gene synonym: GRD6; VPS26; VPT4
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005768 endosome [PMID:9700157]
experiment: EXISTENCE:mutant phenotype:GO:0030904 retromer complex [PMID:9700157]
experiment: EXISTENCE:mutant phenotype:GO:0030906 retromer, cargo-selective complex [PMID:9700157]
experiment: EXISTENCE:mutant phenotype:GO:0045053 protein retention in Golgi apparatus [PMID:8649377]
experiment: EXISTENCE:mutant phenotype:GO:0140318 protein transporter activity [PMID:9700157]
experiment: EXISTENCE:physical interaction:GO:0030904 retromer complex [PMID:9700157]
experiment: EXISTENCE:physical interaction:GO:0042147 retrograde transport, endosome to Golgi [PMID:9700157]
experiment: EXISTENCE:physical interaction:GO:0140318 protein transporter activity [PMID:9700157]
note: Vacuolar protein component of the retromer; forms part of the multimeric membrane-associated retromer complex involved in vacuolar protein sorting along with Vps35p, Vps29p, Vps17p, and Vps5p; essential for endosome-to-Golgi retrograde protein transport; interacts with Ypt7p; protein abundance increases in response to DNA replication stress
codon start: 1
product: retromer subunit PEP8
translation: MSIFFKPPIDIEILFDNEESRKHVDIATRSSNSSYKSMKESLPVYEDGESLGGIVTLRVRDSKKVDHLGIKVSVIGSIDMLKSHGSGNSSSKKVTSSTSSSSSNGSVDVRKNSVDQFLCQSYDLCPAGELQHSQSFPFLFRDLSKRYESYKGKNVDVAYYVKVTVMRKSTDISKIKRFWVYLYNSVTTAPNTLSANETKATTNDIAGGNYAADNASDNTQTKSTQGEAADVNQVLPISHSNNEPKPVRLDIGIENCLHIEFEYAKSQYSLKEVIVGRIYFLLTRLRIKHMELSLITRESSGLQTSNVMTDSTAIRYEIMDGSSVKGETIPIRLFLSGYDLTPNMSCNYFNVKNYLSLVIIDEDGRRYFKQSEITLYRTR
SIO_010081: YJL053W
subclass of: SO_0000673
so part of: YJL053W
location: 335898..337037
location: region:335898-337037:1
so has part: feature:335898-337037:1:exon

NP_012482.1
type: Protein
SIO_000068: ncbiprotein

S000003589
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:335898-337037:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1011; Autonomously Replicating Sequence
so part of: sequence
location: 337281..337529
location: region:337281-337529:1
so has part: feature:337281-337529:1:region

S000028448
type: SGD
SIO_000068: sgd

position:337281:1
position: 337281
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:337529:1
position: 337529
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:337281-337529:1:region

YJL052C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJL052C-A
so part of: sequence
location: complement(<337884..>338003)
location: region:337884-338003:-1
so has part: feature:337884-338003:-1:exon
subclass of: SO_0000010

853394
type: Gene
SIO_000068: ncbigene

position:337884:-1
position: 337884
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:338003:-1
position: 338003
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:337884-338003:-1:exon

YJL052C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJL052C-A
product: uncharacterized protein
transcript id: NM_001184476.1
SIO_010081: YJL052C-A
subclass of: SO_0000673
so part of: YJL052C-A
location: complement(<337884..>338003)
location: region:337884-338003:-1
so has part: feature:337884-338003:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:337884-338003:-1:exon

YJL052C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJL052C-A
note: hypothetical protein; identified based on comparison to related yeast species; mCherry fusion protein localizes to the vacuole
codon start: 1
product: uncharacterized protein
translation: MHLRSRWWLALLYCKDPVSRSATTPKVETRASCLLSRAF
SIO_010081: YJL052C-A
subclass of: SO_0000673
so part of: YJL052C-A
location: complement(337884..338003)
location: region:337884-338003:-1
so has part: feature:337884-338003:-1:exon

NP_076895.1
type: Protein
SIO_000068: ncbiprotein

S000007610
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:337884-338003:-1:exon

YJL052W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: GLD3
gene: TDH1
locus tag: YJL052W
gene synonym: GLD3
so part of: sequence
location: <338271..>339269
location: region:338271-339269:1
so has part: feature:338271-339269:1:exon
subclass of: SO_0000010

853395
type: Gene
SIO_000068: ncbigene

position:338271:1
position: 338271
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:339269:1
position: 339269
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:338271-339269:1:exon

YJL052W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: GLD3
gene: TDH1
locus tag: YJL052W
gene synonym: GLD3
product: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH1
transcript id: NM_001181485.3
SIO_010081: YJL052W
subclass of: SO_0000673
so part of: YJL052W
location: <338271..>339269
location: region:338271-339269:1
so has part: feature:338271-339269:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:338271-339269:1:exon

YJL052W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: GLD3
gene: TDH1
locus tag: YJL052W
gene synonym: GLD3
EC number: 1.2.1.12
experiment: EXISTENCE:direct assay:GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [PMID:3905788]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16962558|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005811 lipid droplet [PMID:10515935]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:11158358|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:16622836]
experiment: EXISTENCE:direct assay:GO:0009277 fungal-type cell wall [PMID:11158358]
experiment: EXISTENCE:direct assay:GO:1904408 melatonin binding [PMID:31708896]
experiment: EXISTENCE:expression pattern:GO:0006094 gluconeogenesis [PMID:3905788]
experiment: EXISTENCE:expression pattern:GO:0006096 glycolytic process [PMID:3905788]
experiment: EXISTENCE:physical interaction:GO:0005739 mitochondrion [PMID:16962558]
note: Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 1; involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell wall; protein abundance increases in response to DNA replication stress; GAPDH-derived antimicrobial peptides secreted by S. cerevisiae are active against a wide variety of wine-related yeasts and bacteria
codon start: 1
product: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH1
translation: MIRIAINGFGRIGRLVLRLALQRKDIEVVAVNDPFISNDYAAYMVKYDSTHGRYKGTVSHDDKHIIIDGVKIATYQERDPANLPWGSLKIDVAVDSTGVFKELDTAQKHIDAGAKKVVITAPSSSAPMFVVGVNHTKYTPDKKIVSNASCTTNCLAPLAKVINDAFGIEEGLMTTVHSMTATQKTVDGPSHKDWRGGRTASGNIIPSSTGAAKAVGKVLPELQGKLTGMAFRVPTVDVSVVDLTVKLEKEATYDQIKKAVKAAAEGPMKGVLGYTEDAVVSSDFLGDTHASIFDASAGIQLSPKFVKLISWYDNEYGYSARVVDLIEYVAKA
SIO_010081: YJL052W
subclass of: SO_0000673
so part of: YJL052W
location: 338271..339269
location: region:338271-339269:1
so has part: feature:338271-339269:1:exon

NP_012483.3
type: Protein
SIO_000068: ncbiprotein

S000003588
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:338271-339269:1:exon

YJL051W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: IRC8
locus tag: YJL051W
so part of: sequence
location: <339787..>342255
location: region:339787-342255:1
so has part: feature:339787-342255:1:exon
subclass of: SO_0000010

853396
type: Gene
SIO_000068: ncbigene

position:339787:1
position: 339787
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:342255:1
position: 342255
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:339787-342255:1:exon

YJL051W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: IRC8
locus tag: YJL051W
product: Irc8p
transcript id: NM_001181484.1
SIO_010081: YJL051W
subclass of: SO_0000673
so part of: YJL051W
location: <339787..>342255
location: region:339787-342255:1
so has part: feature:339787-342255:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:339787-342255:1:exon

YJL051W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: IRC8
locus tag: YJL051W
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005933 cellular bud [PMID:13679573]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0006312 mitotic recombination [PMID:18085829]
note: Bud tip localized hypothetical protein; mRNA is targeted to the bud by a She2p dependent transport system; mRNA is cell cycle regulated via Fkh2p, peaking in G2/M phase; null mutant displays increased levels of spontaneous Rad52p foc
codon start: 1
product: Irc8p
translation: MCHNSVRSGNKAGFLGIKFGSALLSIATGAIAIALLCKFHDHEAVLIVIVCSTLLYGIPSLISFITETVFAPSKFHIGYFYNVLNFALPLITMGCTVDYFHNTLRSPISVQSESHRVYITTLDSLLIFTLFINGIQLGFFLKDGNANNFGSSSNNISTDQYDKEANAVENGRFVPLKNSSQTLTPDLELLHGSPKSMNGVAWLINELSTNSNTNANKTISSDENSNSSVIRHKLGPISTSKCPKKPSHSHFSKLKKYNSFFLGPKENRYKRNTQQATKVPTEKKSNHRSSQYVSRLSTISDISKSFLNFLALNEKNGNSTSTARTPSEGRVSIIINEGNNTLKYKTPHDSHTIDSPNLELEREAIGRINSALLPACLRVTDKMISPQQSTQNEDSYQATPLIPQVEVDDDFYVGDILMTNELQDIPQVPRISSDIEDDFEQQYTKHVDLPARVTLEMWEKDQEKILQKVTTNRDKSKLLPPFRFTSESDMDPSTSTELEVELHAQNNFSFPFKSAGLQIATSDQFNQQEFKTSDTISELDEYLHDPSIQEEDASQLIESSLNQNNLSSTTIDNGPKDMSRFSTRHSPTKSIISMISGSGSVKHQHSHSTLSNFFTGHSRNNSQINQLLQGSSSNMMSNTSPHSSPTKSLRMRFGKKLSLSNISDTMSPYEGSTTDPINYSFGHGHNKNQSIDFSYVRTLQSSHSPTKSTSGNSRRDSLNNDRTQSTVNERALRTASTLFYLQHNNATCTLNGEEPVLDTPQSIQSSSSGSEQESAGSGSGYPEVVFSEYDREKWNVLRNLKEIAPEKTIESGPVEELVSPSK
SIO_010081: YJL051W
subclass of: SO_0000673
so part of: YJL051W
location: 339787..342255
location: region:339787-342255:1
so has part: feature:339787-342255:1:exon

NP_012484.1
type: Protein
SIO_000068: ncbiprotein

S000003587
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:339787-342255:1:exon

YJL050W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: DOB1
gene: MTR4
locus tag: YJL050W
gene synonym: DOB1
so part of: sequence
location: <342522..>345743
location: region:342522-345743:1
so has part: feature:342522-345743:1:exon
subclass of: SO_0000010

853397
type: Gene
SIO_000068: ncbigene

position:342522:1
position: 342522
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:345743:1
position: 345743
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:342522-345743:1:exon

YJL050W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: DOB1
gene: MTR4
locus tag: YJL050W
gene synonym: DOB1
product: ATP-dependent RNA helicase MTR4
transcript id: NM_001181483.1
SIO_010081: YJL050W
subclass of: SO_0000673
so part of: YJL050W
location: <342522..>345743
location: region:342522-345743:1
so has part: feature:342522-345743:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:342522-345743:1:exon

YJL050W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: DOB1
gene: MTR4
locus tag: YJL050W
gene synonym: DOB1
EC number: 3.6.4.13
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:15226447|PMID:8756671]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:16541108]
experiment: EXISTENCE:direct assay:GO:0008143 poly(A) binding [PMID:18096702]
experiment: EXISTENCE:direct assay:GO:0031499 TRAMP complex [PMID:15828860|PMID:15935758|PMID:15935759]
experiment: EXISTENCE:direct assay:GO:0034458 3'-5' RNA helicase activity [PMID:18000032|PMID:18096702]
experiment: EXISTENCE:direct assay:GO:0043629 ncRNA polyadenylation [PMID:15828860|PMID:15935758]
experiment: EXISTENCE:direct assay:GO:0071038 nuclear polyadenylation-dependent tRNA catabolic process [PMID:15828860|PMID:15935758|PMID:17643380]
experiment: EXISTENCE:genetic interaction:GO:0071028 nuclear mRNA surveillance [PMID:11586364]
experiment: EXISTENCE:genetic interaction:GO:0071038 nuclear polyadenylation-dependent tRNA catabolic process [PMID:18000032]
experiment: EXISTENCE:mutant phenotype:GO:0000467 exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:10508172|PMID:9463390]
experiment: EXISTENCE:mutant phenotype:GO:0006397 mRNA processing [PMID:27385342]
experiment: EXISTENCE:mutant phenotype:GO:0016075 rRNA catabolic process [PMID:10508172|PMID:9463390]
experiment: EXISTENCE:mutant phenotype:GO:0034458 3'-5' RNA helicase activity [PMID:18000032]
experiment: EXISTENCE:mutant phenotype:GO:0034475 U4 snRNA 3'-end processing [PMID:10508172|PMID:10611222]
experiment: EXISTENCE:mutant phenotype:GO:0034476 U5 snRNA 3'-end processing [PMID:10508172]
experiment: EXISTENCE:mutant phenotype:GO:0071031 nuclear mRNA surveillance of mRNA 3'-end processing [PMID:17410208]
experiment: EXISTENCE:mutant phenotype:GO:0071035 nuclear polyadenylation-dependent rRNA catabolic process [PMID:16374505|PMID:18940861]
experiment: EXISTENCE:mutant phenotype:GO:0071042 nuclear polyadenylation-dependent mRNA catabolic process [PMID:19369424]
experiment: EXISTENCE:mutant phenotype:GO:0071051 polyadenylation-dependent snoRNA 3'-end processing [PMID:10611222]
experiment: EXISTENCE:physical interaction:GO:0031499 TRAMP complex [PMID:15935759]
note: RNA duplex-sensing translocase; ATP-dependent 3'-5' RNA helicase of the DExD/H family; involved in nuclear RNA processing and degradation as a component of TRAMP complex and in TRAMP-independent processes; TRAMP unwinds RNA duplexes, with Mtr4p unwinding activity stimulated by Pap2p/Air2p but not dependent on ongoing polyadenylation; contains an arch domain, with two coiled-coil arms/stalks and a globular fist/KOW domain, which has RNA binding activity and is required for 5.8S rRNA processing
codon start: 1
product: ATP-dependent RNA helicase MTR4
translation: MDSTDLFDVFEETPVELPTDSNGEKNADTNVGDTPDHTQDKKHGLEEEKEEHEENNSENKKIKSNKSKTEDKNKKVVVPVLADSFEQEASREVDASKGLTNSETLQVEQDGKVRLSHQVRHQVALPPNYDYTPIAEHKRVNEARTYPFTLDPFQDTAISCIDRGESVLVSAHTSAGKTVVAEYAIAQSLKNKQRVIYTSPIKALSNQKYRELLAEFGDVGLMTGDITINPDAGCLVMTTEILRSMLYRGSEVMREVAWVIFDEVHYMRDKERGVVWEETIILLPDKVRYVFLSATIPNAMEFAEWICKIHSQPCHIVYTNFRPTPLQHYLFPAHGDGIYLVVDEKSTFREENFQKAMASISNQIGDDPNSTDSRGKKGQTYKGGSAKGDAKGDIYKIVKMIWKKKYNPVIVFSFSKRDCEELALKMSKLDFNSDDEKEALTKIFNNAIALLPETDRELPQIKHILPLLRRGIGIHHSGLLPILKEVIEILFQEGFLKVLFATETFSIGLNMPAKTVVFTSVRKWDGQQFRWVSGGEYIQMSGRAGRRGLDDRGIVIMMIDEKMEPQVAKGMVKGQADRLDSAFHLGYNMILNLMRVEGISPEFMLEHSFFQFQNVISVPVMEKKLAELKKDFDGIEVEDEENVKEYHEIEQAIKGYREDVRQVVTHPANALSFLQPGRLVEISVNGKDNYGWGAVVDFAKRINKRNPSAVYTDHESYIVNVVVNTMYIDSPVNLLKPFNPTLPEGIRPAEEGEKSICAVIPITLDSIKSIGNLRLYMPKDIRASGQKETVGKSLREVNRRFPDGIPVLDPVKNMKIEDEDFLKLMKKIDVLNTKLSSNPLTNSMRLEELYGKYSRKHDLHEDMKQLKRKISESQAVIQLDDLRRRKRVLRRLGFCTPNDIIELKGRVACEISSGDELLLTELIFNGNFNELKPEQAAALLSCFAFQERCKEAPRLKPELAEPLKAMREIAAKIAKIMKDSKIEVVEKDYVESFRHELMEVVYEWCRGATFTQICKMTDVYEGSLIRMFKRLEELVKELVDVANTIGNSSLKEKMEAVLKLIHRDIVSAGSLYL
SIO_010081: YJL050W
subclass of: SO_0000673
so part of: YJL050W
location: 342522..345743
location: region:342522-345743:1
so has part: feature:342522-345743:1:exon

NP_012485.1
type: Protein
SIO_000068: ncbiprotein

S000003586
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:342522-345743:1:exon

YJL049W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CHM7
locus tag: YJL049W
so part of: sequence
location: <345973..>347325
location: region:345973-347325:1
so has part: feature:345973-347325:1:exon
subclass of: SO_0000010

853398
type: Gene
SIO_000068: ncbigene

position:345973:1
position: 345973
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:347325:1
position: 347325
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:345973-347325:1:exon

YJL049W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CHM7
locus tag: YJL049W
product: Chm7p
transcript id: NM_001181482.3
SIO_010081: YJL049W
subclass of: SO_0000673
so part of: YJL049W
location: <345973..>347325
location: region:345973-347325:1
so has part: feature:345973-347325:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:345973-347325:1:exon

YJL049W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CHM7
locus tag: YJL049W
note: Yeast homolog of human CHMP7, localizes to the endoplasmic reticulum presumably as part of an ESCRT-III like complex; null mutant has growth defect at 37 C in an apq12 deletion background; non-essential gene
codon start: 1
product: Chm7p
translation: MKVDLPESRLPSLYRDFRPLKDLNPDGYEANISTWRDFFLQQYISNSNRIIFTIGTRTLQELTHEVYGVPKSIDIAIDVLVNEGNLIPMELFNLGGMYTDNSRKGFWKWVRSWKESTNMYKSRKDETNFYLREDKFIIKANLEKEYQRFHELLKRSVFMEASSITDLVFTRNEFVTTESLQSFFSTYDEETKNVFLHFIENYKHIIVSKDNVIKVIAAEVEDITSRFSKGITENDLRIASVKVGIININKQITRLRKEINESNIKLRGPEFNELPKRIRIEYKQARLLSEKHLSRLLKFQNNLAQVRTQIDTSATNAVLIQTLSESNEVIKSINGYIGSTEKVEDLLDEIKEGHDRTEEVNDLLAHYNKGQDEEAEEEIERELEQLELDEKNNNKEENKNQDLHEPKESSSEDLLKRLNNLKINTNEGPVQDNENHDNEIRKIMMEEQPR
SIO_010081: YJL049W
subclass of: SO_0000673
so part of: YJL049W
location: 345973..347325
location: region:345973-347325:1
so has part: feature:345973-347325:1:exon

NP_012486.3
type: Protein
SIO_000068: ncbiprotein

S000003585
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:345973-347325:1:exon

YJL048C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CUI2
gene: UBX6
locus tag: YJL048C
gene synonym: CUI2
so part of: sequence
location: complement(<347447..>348637)
location: region:347447-348637:-1
so has part: feature:347447-348637:-1:exon
subclass of: SO_0000010

853399
type: Gene
SIO_000068: ncbigene

position:347447:-1
position: 347447
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:348637:-1
position: 348637
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:347447-348637:-1:exon

YJL048C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CUI2
gene: UBX6
locus tag: YJL048C
gene synonym: CUI2
product: Ubx6p
transcript id: NM_001181481.1
SIO_010081: YJL048C
subclass of: SO_0000673
so part of: YJL048C
location: complement(<347447..>348637)
location: region:347447-348637:-1
so has part: feature:347447-348637:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:347447-348637:-1:exon

YJL048C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CUI2
gene: UBX6
locus tag: YJL048C
gene synonym: CUI2
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14755638]
experiment: EXISTENCE:mutant phenotype:GO:0006511 ubiquitin-dependent protein catabolic process [PMID:14755638]
experiment: EXISTENCE:mutant phenotype:GO:0030435 sporulation resulting in formation of a cellular spore [PMID:14755638]
note: UBX (ubiquitin regulatory X) domain-containing protein; interacts with Cdc48p, transcription is repressed when cells are grown in media containing inositol and choline; UBX6 has a paralog, UBX7, that arose from the whole genome duplication
codon start: 1
product: Ubx6p
translation: MYEMSGIDSLFHDRVVHDYSHTSEQVIVVYISSAAGDNSWLHQWFKPGNLSDEERENILWVRLVNGTKECLLFKSIFPSSSAPSINILQNGLLECSIQGNSLSREQDPWETFINGLQSVFKGQVTKRKLFSKSNEEYQRVKRMIQNDKLERKYVFQNTNDPQRKPQKWKQLTVTDNVSYKSQKGFLAQNYCTLQLKLPNGYTISNTFPPQTKLHKVRMWLDYNCYDDGTPYLFHRNIPRVTLTRNDELKSLQELDLLPRSTLILEPLEANNKTFDYMEQSSLLHKVYSGLTSFWAKEPEVDASSSRLGYQRLGTNVSNSANYSLQKLSSLDMVSDGGGGGGGDSMTPSAYTTPRMYPSNGTSQLRQNVSELNLSSNNSASNTKVRTLGYSNNNGNN
SIO_010081: YJL048C
subclass of: SO_0000673
so part of: YJL048C
location: complement(347447..348637)
location: region:347447-348637:-1
so has part: feature:347447-348637:-1:exon

NP_012487.1
type: Protein
SIO_000068: ncbiprotein

S000003584
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:347447-348637:-1:exon

YJL047C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJL047C-A
so part of: sequence
location: complement(<349044..>349178)
location: region:349044-349178:-1
so has part: feature:349044-349178:-1:exon
subclass of: SO_0000010

1466468
type: Gene
SIO_000068: ncbigene

position:349044:-1
position: 349044
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:349178:-1
position: 349178
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:349044-349178:-1:exon

YJL047C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJL047C-A
product: uncharacterized protein
transcript id: NM_001184635.1
SIO_010081: YJL047C-A
subclass of: SO_0000673
so part of: YJL047C-A
location: complement(<349044..>349178)
location: region:349044-349178:-1
so has part: feature:349044-349178:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:349044-349178:-1:exon

YJL047C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJL047C-A
codon start: 1
product: uncharacterized protein
translation: MKIKISIEISLSLLSEHYKRNENCISNMLVIGEGPRGETIVERF
SIO_010081: YJL047C-A
subclass of: SO_0000673
so part of: YJL047C-A
location: complement(349044..349178)
location: region:349044-349178:-1
so has part: feature:349044-349178:-1:exon

NP_878105.1
type: Protein
SIO_000068: ncbiprotein

S000028804
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:349044-349178:-1:exon

YNCJ0009C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SNR60
locus tag: YNCJ0009C
so part of: sequence
location: complement(349130..349233)
location: region:349130-349233:-1
so has part: feature:349130-349233:-1:exon
subclass of: SO_0000578

9164911
type: Gene
SIO_000068: ncbigene

position:349130:-1
position: 349130
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:349233:-1
position: 349233
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:349130-349233:-1:exon

YNCJ0009C
type: Non Coding RNA
subclass of: SO_0000655
RO_0002162: 559292
nc RNA class: snoRNA
gene: SNR60
locus tag: YNCJ0009C
product: SNR60
experiment: EXISTENCE:curator inference:GO:0005730 nucleolus [PMID:10024243]
experiment: EXISTENCE:curator inference:GO:0031428 box C/D RNP complex [PMID:10024243]
experiment: EXISTENCE:mutant phenotype:GO:0030562 rRNA 2'-O-ribose methylation guide activity [PMID:10024243]
experiment: EXISTENCE:mutant phenotype:GO:0031167 rRNA methylation [PMID:10024243]
note: C/D box small nucleolar RNA (snoRNA); guides 2'-O-methylation of large subunit (LSU) rRNA at positions A817 and G908
transcript id: NR_132196.1
SIO_010081: YNCJ0009C
subclass of: SO_0000673
so part of: YNCJ0009C
location: complement(349130..349233)
location: region:349130-349233:-1
so has part: feature:349130-349233:-1:exon

S000006451
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:349130-349233:-1:exon

YJL047C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CUL8
gene: RTT101
locus tag: YJL047C
gene synonym: CUL8
so part of: sequence
location: complement(<349580..>352108)
location: region:349580-352108:-1
so has part: feature:349580-352108:-1:exon
subclass of: SO_0000010

853400
type: Gene
SIO_000068: ncbigene

position:349580:-1
position: 349580
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:352108:-1
position: 352108
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:349580-352108:-1:exon

YJL047C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CUL8
gene: RTT101
locus tag: YJL047C
gene synonym: CUL8
product: cullin RTT101
transcript id: NM_001181480.3
SIO_010081: YJL047C
subclass of: SO_0000673
so part of: YJL047C
location: complement(<349580..>352108)
location: region:349580-352108:-1
so has part: feature:349580-352108:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:349580-352108:-1:exon

YJL047C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CUL8
gene: RTT101
locus tag: YJL047C
gene synonym: CUL8
experiment: EXISTENCE:curator inference:GO:0006511 ubiquitin-dependent protein catabolic process [PMID:12676951]
experiment: EXISTENCE:direct assay:GO:0004842 ubiquitin-protein transferase activity [PMID:12676951]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0035361 Cul8-RING ubiquitin ligase complex [PMID:20139071]
experiment: EXISTENCE:mutant phenotype:GO:0007088 regulation of mitotic nuclear division [PMID:12676951]
experiment: EXISTENCE:mutant phenotype:GO:0010526 negative regulation of transposition, RNA-mediated [PMID:11779788]
experiment: EXISTENCE:mutant phenotype:GO:0031297 replication fork processing [PMID:18704118]
experiment: EXISTENCE:mutant phenotype:GO:0070651 nonfunctional rRNA decay [PMID:19390089|PMID:22505030]
note: Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex; role in anaphase progression; Rtt101p-Mms22p ligase associates with replisome complex during S phase via Ctf4p; required for recovery after DSB repair; implicated in Mms22-dependent DNA repair; involved with Mms1p in nonfunctional rRNA decay; modified by the ubiquitin-like protein, Rub1p
codon start: 1
product: cullin RTT101
translation: MINESVSKREGFHESISRETSASNALGLYNKFNDERNPRYRTMIAELHEFFHLTLAETITETDVKELECNKEKAAKFRKLMPKMLNNCRELTQRKSYIPYNSEFNGNDEKQKKFQLLHQHQIVLSFQEFCDELAKLIIDAHVLSFLTRCDYSYEIIPKNWTSFYKLFQYVMGAVGPIISYVPVNYPMIRKELGFETLTIFQYYDSKLFECMKSHFGREFSTLVSATIHHYIHMFPITNTMLEKEVPMLRIMSNCNFSIEGLSPKDFYMKTLRQYYCEESNLRPRLETFKNFKVLLTRNALLASLFSPEWVSDANDLFISHLLLNKKSISEYIEIGKDTYDEEKERYFKTETHFSLLMFRNAFEAKNMLSKFKEFCDDAVSEKLKAAYGSNHDTERLFDEVVQLANVDHLKIYSDSIEYHLCNLLGSTSKAIEQYVKYFESHLFIIVRKIKTTKKDLPRDMKIKYLNENLPILRLKFVNLPTFPNFFERSIFRKTILQSDQNSSFIKDILPVYKDSLMELFKQRIITNVSQEDEMRYRDQYQPYLSQFFQPVEVMADLRIKYASFLSFYENIEAAVKFGKTYNENNSKSFFPLIFDRERIPKVFQQSNEVKKNFVLPQEMDDTWNQFLRNYHEQNKVEDSDASKKELYPMWNLHHCEVESPYIIQDGTNLIFELTLFQTCVLTLFNESDHLTLQVISEQTKLAYKDLALVLKSFCNYKILTRDIDNTYSINESFKPDMKKVKNGKLRVVLPRTASLQSSNTGGERTSSAHHEGSNSQWTQELLKACITRSVKSERNGLDYDHLFETVKQQIKGFSVGEFKDALAKLLRDKFITRDESTATYKY
SIO_010081: YJL047C
subclass of: SO_0000673
so part of: YJL047C
location: complement(349580..352108)
location: region:349580-352108:-1
so has part: feature:349580-352108:-1:exon

NP_012488.3
type: Protein
SIO_000068: ncbiprotein

S000003583
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:349580-352108:-1:exon

YJL046W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LIP3
alternative label: RRG3
gene: AIM22
locus tag: YJL046W
gene synonym: LIP3; RRG3
so part of: sequence
location: <352386..>353615
location: region:352386-353615:1
so has part: feature:352386-353615:1:exon
subclass of: SO_0000010

853401
type: Gene
SIO_000068: ncbigene

position:352386:1
position: 352386
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:353615:1
position: 353615
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:352386-353615:1:exon

YJL046W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LIP3
alternative label: RRG3
gene: AIM22
locus tag: YJL046W
gene synonym: LIP3; RRG3
product: putative lipoate--protein ligase
transcript id: NM_001181479.1
SIO_010081: YJL046W
subclass of: SO_0000673
so part of: YJL046W
location: <352386..>353615
location: region:352386-353615:1
so has part: feature:352386-353615:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:352386-353615:1:exon

YJL046W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LIP3
alternative label: RRG3
gene: AIM22
locus tag: YJL046W
gene synonym: LIP3; RRG3
EC number: 6.3.1.20
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:19570983]
experiment: EXISTENCE:mutant phenotype:GO:0009249 protein lipoylation [PMID:19570983]
note: Lipoate-protein ligase; octanoyl-CoA: protein transferase required along with Lip2 and Lip5 for lipoylation of Lat1p and Kgd2p; similar to E. coli LplA; null mutant displays reduced frequency of mitochondrial genome loss
codon start: 1
product: putative lipoate--protein ligase
translation: MSMMLSNWALSPRYVGQRNLIHCTTLFHTLTRWAKDADDKYHDINSMYENMFTPSNDNVSILQDEGKSDYDTTKASSMEEDISAFNKDLYNFYNIGYAKQIMSASQLENIVKAKGRFVIQSLSTSPYYNLALENYVFKNTPRAKRGPDNCRLLFYINDRCAVIGKNQNLWQEVDLAKLKSKNFELLRRFSGGGTVLHDLGNVNYSYLTSREKFETKFFNKMIIKWLNSLNPELRLDLNERGDIIQDGFKISGSAYKIAGGKAYHHATMLLNADLEQFSGLLEPSLPNNMEWESSGVHSVKSKIKNVGIITPNQFIAVVSERFQKTFKVDGEIPIYYCDEFKSINDEIKDAMNTLQSEQWKYFSGPKFSVKIKDKGLTIKVEKGMIYDCDRNDLIGLEFKGFLENIDSYT
SIO_010081: YJL046W
subclass of: SO_0000673
so part of: YJL046W
location: 352386..353615
location: region:352386-353615:1
so has part: feature:352386-353615:1:exon

NP_012489.2
type: Protein
SIO_000068: ncbiprotein

S000003582
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:352386-353615:1:exon

YNCJ0010W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SUP7
locus tag: YNCJ0010W
so part of: sequence
location: 354244..354332
location: region:354244-354332:1
so has part: feature:354244-354332:1:exon
subclass of: SO_0000663

853402
type: Gene
SIO_000068: ncbigene

position:354244:1
position: 354244
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:354332:1
position: 354332
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:354244-354332:1:exon

YNCJ0010W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
gene: SUP7
locus tag: YNCJ0010W
product: tRNA-Tyr
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Tyrosine tRNA (tRNA-Tyr), predicted by tRNAscan-SE analysis; can mutate to suppress ochre nonsense mutations
SIO_010081: YNCJ0010W
subclass of: SO_0000673
so part of: YNCJ0010W
location: join(354244..354282,354297..354332)
location: region:354244-354332:1
so has part: feature:354244-354282:1:exon
so has part: feature:354297-354332:1:exon

S000006781
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:354244-354282:1:exon

position:354282:1
position: 354282
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:354297-354332:1:exon

position:354297:1
position: 354297
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(354538..355204)
location: region:354538-355204:-1
so has part: feature:354538-355204:-1:region

S000007023
type: SGD
SIO_000068: sgd

position:354538:-1
position: 354538
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:355204:-1
position: 355204
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:354538-355204:-1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(354844..355175)
location: region:354844-355175:-1
so has part: feature:354844-355175:-1:region

S000007024
type: SGD
SIO_000068: sgd

position:354844:-1
position: 354844
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:355175:-1
position: 355175
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:354844-355175:-1:region

YNCJ0011W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCJ0011W
so part of: sequence
location: 355374..355445
location: region:355374-355445:1
so has part: feature:355374-355445:1:exon
subclass of: SO_0000663

853403
type: Gene
SIO_000068: ncbigene

position:355374:1
position: 355374
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:355445:1
position: 355445
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:355374-355445:1:exon

YNCJ0011W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCJ0011W
product: tRNA-Arg
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Arginine tRNA (tRNA-Arg), predicted by tRNAscan-SE analysis; one of 11 nuclear tRNA genes containing the tDNA-anticodon UCU (converted to mcm5-UCU in the mature tRNA), decodes AGA codons into arginine, one of 19 nuclear tRNAs for arginine
SIO_010081: YNCJ0011W
subclass of: SO_0000673
so part of: YNCJ0011W
location: 355374..355445
location: region:355374-355445:1
so has part: feature:355374-355445:1:exon

S000006714
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:355374-355445:1:exon

YNCJ0012W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCJ0012W
so part of: sequence
location: 355456..355527
location: region:355456-355527:1
so has part: feature:355456-355527:1:exon
subclass of: SO_0000663

853404
type: Gene
SIO_000068: ncbigene

position:355456:1
position: 355456
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:355527:1
position: 355527
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:355456-355527:1:exon

YNCJ0012W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCJ0012W
product: tRNA-Asp
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Aspartate tRNA (tRNA-Asp), predicted by tRNAscan-SE analysis
SIO_010081: YNCJ0012W
subclass of: SO_0000673
so part of: YNCJ0012W
location: 355456..355527
location: region:355456-355527:1
so has part: feature:355456-355527:1:exon

S000006537
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:355456-355527:1:exon

YJL045W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SDH9
locus tag: YJL045W
so part of: sequence
location: <356024..>357928
location: region:356024-357928:1
so has part: feature:356024-357928:1:exon
subclass of: SO_0000010

853405
type: Gene
SIO_000068: ncbigene

position:356024:1
position: 356024
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:357928:1
position: 357928
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:356024-357928:1:exon

YJL045W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SDH9
locus tag: YJL045W
product: succinate dehydrogenase SDH1b
transcript id: NM_001181478.1
SIO_010081: YJL045W
subclass of: SO_0000673
so part of: YJL045W
location: <356024..>357928
location: region:356024-357928:1
so has part: feature:356024-357928:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:356024-357928:1:exon

YJL045W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SDH9
locus tag: YJL045W
EC number: 1.3.5.1
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:genetic interaction:GO:0008177 succinate dehydrogenase (ubiquinone) activity [PMID:16232921|PMID:9730279]
experiment: EXISTENCE:genetic interaction:GO:0045333 cellular respiration [PMID:16232921|PMID:9730279]
experiment: EXISTENCE:mutant phenotype:GO:0008177 succinate dehydrogenase (ubiquinone) activity [PMID:16232921]
experiment: EXISTENCE:mutant phenotype:GO:0045333 cellular respiration [PMID:16232921]
note: Minor succinate dehydrogenase isozyme; participates in oxidation of succinate and transfer of electrons to ubiquinone; induced during the diauxic shift in a Cat8p-dependent manner; YJL045W has a paralog, SDH1, that arose from the whole genome duplication
codon start: 1
product: succinate dehydrogenase SDH1b
translation: MLSLKKGITKSYILQRTFTSSSVVRQIGEVKSESKPPAKYHIIDHEYDCVVVGAGGAGLRAAFGLAEAGYKTACLSKLFPTRSHTVAAQGGINAALGNMHPDDWKSHMYDTVKGSDWLGDQDAIHYMTREAPKSVIELEHYGMPFSRTEDGRIYQRAFGGQSKDFGKGGQAYRTCAVADRTGHAMLHTLYGQALKNNTHFFIEYFAMDLLTHNGEVVGVIAYNQEDGTIHRFRAHKTVIATGGYGRAYFSCTSAHTCTGDGNAMVSRAGFPLEDLEFVQFHPSGIYGSGCLITEGARGEGGFLLNSEGERFMERYAPTAKDLASRDVVSRAITMEIRAGRGVGKNKDHILLQLSHLPPEVLKERLPGISETAAVFAGVDVTQEPIPVLPTVHYNMGGIPTKWTGEALTIDEETGEDKVIPGLMACGEAACVSVHGANRLGANSLLDLVVFGRAVANTIADTLQPGLPHKPLASNIGHESIANLDKVRNARGSLKTSQIRLNMQRTMQKDVSVFRTQDTLDEGVRNITEVDKTFEDVHVSDKSMIWNSDLVETLELQNLLTCATQTAVSASKRKESRGAHAREDYAKRDDVNWRKHTLSWQKGTSTPVKIKYRNVIAHTLDENECAPVPPAVRSY
SIO_010081: YJL045W
subclass of: SO_0000673
so part of: YJL045W
location: 356024..357928
location: region:356024-357928:1
so has part: feature:356024-357928:1:exon

NP_012490.1
type: Protein
SIO_000068: ncbiprotein

S000003581
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:356024-357928:1:exon

YJL044C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GYP6
locus tag: YJL044C
so part of: sequence
location: complement(<358300..>359676)
location: region:358300-359676:-1
so has part: feature:358300-359676:-1:exon
subclass of: SO_0000010

853406
type: Gene
SIO_000068: ncbigene

position:358300:-1
position: 358300
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:359676:-1
position: 359676
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:358300-359676:-1:exon

YJL044C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GYP6
locus tag: YJL044C
product: GTPase-activating protein GYP6
transcript id: NM_001181477.3
SIO_010081: YJL044C
subclass of: SO_0000673
so part of: YJL044C
location: complement(<358300..>359676)
location: region:358300-359676:-1
so has part: feature:358300-359676:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:358300-359676:-1:exon

YJL044C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GYP6
locus tag: YJL044C
experiment: EXISTENCE:direct assay:GO:0005096 GTPase activator activity [PMID:8441469]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:35134079]
experiment: EXISTENCE:direct assay:GO:0005768 endosome [PMID:14610088]
experiment: EXISTENCE:direct assay:GO:0005802 trans-Golgi network [PMID:24924636]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0030136 clathrin-coated vesicle [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0090630 activation of GTPase activity [PMID:8441469]
note: GTPase-activating protein (GAP) for yeast Rab family member Ypt6p; involved in vesicle mediated protein transport
codon start: 1
product: GTPase-activating protein GYP6
translation: MKDVLQWAIDHYETRDQLVQKGIWKGELYHDSIFKENSRGWLWKALLLCDENNNCLLTDNFKGLDLNQFGLVPVPMLADGDNYDENHNANVPKRVLHSNVSSSVGIRRLTPVEAVEKHPLSDDNDKTKGSLSKGSDEKPLTLRETLEIIDLDLSRIMLDDIFQEPKVHAQMRQLLYNYLLIHQSEHLQYKQGFHEILSVIYLQLYHGTDLDNTDLQNVLIIFNKLMNQIEPIFYNEENLINWDKRVFTKIFRICLPDLFSKVFYQPPKTGSGKKKNVDHLIHSNLIWLIRWTRLLFLRELPLKYVLIVWDHVLTFNYPLDIFIACTIITLLLSIYDELHELVSQGDYEHTNNNDEFVELILHFKKIFEKEDASKDDEKFLDLCKVTGNLCELWYGKNYDDMRLICDTFINAKFGIKTSDVLSMETAKLTIDPNRQSLENKLRERVRQTILKNKKKISQ
SIO_010081: YJL044C
subclass of: SO_0000673
so part of: YJL044C
location: complement(358300..359676)
location: region:358300-359676:-1
so has part: feature:358300-359676:-1:exon

NP_012491.3
type: Protein
SIO_000068: ncbiprotein

S000003580
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:358300-359676:-1:exon

YJL043W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJL043W
so part of: sequence
location: <360130..>360903
location: region:360130-360903:1
so has part: feature:360130-360903:1:exon
subclass of: SO_0000010

853407
type: Gene
SIO_000068: ncbigene

position:360130:1
position: 360130
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:360903:1
position: 360903
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:360130-360903:1:exon

YJL043W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJL043W
product: uncharacterized protein
transcript id: NM_001181476.1
SIO_010081: YJL043W
subclass of: SO_0000673
so part of: YJL043W
location: <360130..>360903
location: region:360130-360903:1
so has part: feature:360130-360903:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:360130-360903:1:exon

YJL043W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJL043W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095]
note: hypothetical protein; YJL043W is a non-essential gene
codon start: 1
product: uncharacterized protein
translation: MFVDYSGLERYTDINASFGKLVNTYCCFQRCEAISEQLEILKSLVPKCHDIVALTDEDFASGRTAGLTQKLFAMAMTLHQITDCIDLLQKCNTIIPIEIANPASFESGAATAPLRQSYARLLDDWSHYMGPSTVKHTGCTNRPKWRFPWQQSRTIIIPMLFIGETAMSTRDLRSVLHDCEIRHASEMPLQLLWTSSPELVYATPHVDDYDIWSRYGSDYNMQIEDEDEASKGRQRKCVVQLEALLGALPTTDPLFQW
SIO_010081: YJL043W
subclass of: SO_0000673
so part of: YJL043W
location: 360130..360903
location: region:360130-360903:1
so has part: feature:360130-360903:1:exon

NP_012492.1
type: Protein
SIO_000068: ncbiprotein

S000003579
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:360130-360903:1:exon

YJL042W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MHP1
locus tag: YJL042W
so part of: sequence
location: <361249..>365445
location: region:361249-365445:1
so has part: feature:361249-365445:1:exon
subclass of: SO_0000010

853408
type: Gene
SIO_000068: ncbigene

position:361249:1
position: 361249
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:365445:1
position: 365445
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:361249-365445:1:exon

YJL042W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MHP1
locus tag: YJL042W
product: Mhp1p
transcript id: NM_001181475.1
SIO_010081: YJL042W
subclass of: SO_0000673
so part of: YJL042W
location: <361249..>365445
location: region:361249-365445:1
so has part: feature:361249-365445:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:361249-365445:1:exon

YJL042W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MHP1
locus tag: YJL042W
experiment: EXISTENCE:direct assay:GO:0005200 structural constituent of cytoskeleton [PMID:9855114]
experiment: EXISTENCE:direct assay:GO:0005874 microtubule [PMID:8947554]
experiment: EXISTENCE:mutant phenotype:GO:0007026 negative regulation of microtubule depolymerization [PMID:9855114]
experiment: EXISTENCE:mutant phenotype:GO:0031505 fungal-type cell wall organization [PMID:9090049]
note: Microtubule-associated protein involved in microtubule organization; involved in assembly and stabilization of microtubules; overproduction results in cell cycle arrest at G2 phase; similar to Drosophila protein MAP and to mammalian MAP4 proteins
codon start: 1
product: Mhp1p
translation: MDSKDTQKLLKEHRIPCIDVGWLVRPSASTSKSSRPGKSESKANSVAPDIQMDTARPPVFETSVDSSSSILSSNDKGRRHSVAASLLMDNQRANAGSTSVPTNIPPPRGRSKSVVETNLSNVEADSGHHHHHRHHHHTEDAPAPKKVGFFKSLFGHRKKDQEQQEKERERKERSPSPTHVDRGAAIRRERTATISAESPPPLQYNAPPSYNDTVVPLTRSKTESEVYYENHPQSYYHGRMRTYHSPEEGKVDGTSPADDHNYGGSRPDPRLMDFLRYYKSKDYKLAAFKEGNFIKSSASPTTKKNRRASFSLHNDKPQPAKSLAHQKFDAKGRPIPPHPDAPKLPSAFRKKHPSNASIVDTVDSNSDVSSSAQNNNQTPSSHKFGAFLRKVTSYGNNNNNSTNASSLSANVNNPDTSSTSLWSSSSMEFDPSKITTVPGLENIRPLKHVSFATNTYFNDPPQQICSKNPRKGEVEVKPNGSVVIHRLTPQERKKIMESTSLGVVVGGTGQLKLLNPEEDDANAKSKEEMAPQKQNEVEAHDEEDNNSQRRNIVMAAAEAAAEARAKEAPNELKRIVTNNEEEVTVSKTASHLTIDKPMISRRGASTSSLASMVSSDTNGTNADDEGEILPPPSLKIPHDIVYTRCCHLREILPIPATLKQLKKGSTDPIPILQLRNPRPSMVEIWSFSDFLSIAPVLCLSLDGVQLTVQMLRIILSSLVYKQHFQKLSLRNTPLDEEGWKVLCYFVSKAKSLHSIDLTMVPSIKTNVQKPSKSSLKSKILRMQCNLENRSDMNWDLLTASIALMGGLEEIVISGAKMNSAQFKNFILVACIATERLGLAYNGLSKSQCDDLAKWMVQSKVTGLDVGFNDLNGKLSSFTDAVLGKIQKANEKNVFKFLSLNGTNLRVNEHDTFENNEVLKLISVLCYLENLKFLDISNNPAIFPHCVPTLIDFLPVFVNLVRLHIDYNNLSSTSVVMLAEILPMCSRLNYFSMLGTELDLASSKALAEAVRKSSSLMTLDVDYVYMPENIKEKISLYALRNIQGELKRVNSDDKDIKDSQFSSLQDQLSLLLTEKADNSEHYNKMVENFMAKIALARIKISKVVHDLFDLKLNGQLNLEGKEALIRLCFIEASLERGCDLLKQRHNNTLKSPEAVSKSRKGGNQAQPNSESCQRMLLSSSILQNSDHIALMPFGSAIVEKSSPDAEDAVEFREGDDSNVNHEDVPANDQQFRDEVDIKNKYSIIKRELEHEKLVGGGDLPVDKEILNRAAQSLDSDQIKEFLLKNDVSTILGVIDELHSQGYHLHHIFKKQGNQEETAFRTKDEQQSSQSNDSSANASPTTDPISTGSNTSRTNDNAHIPPTDAPGFDKFMNNAEENAIDAAYDDVLDKIQDARNSSTK
SIO_010081: YJL042W
subclass of: SO_0000673
so part of: YJL042W
location: 361249..365445
location: region:361249-365445:1
so has part: feature:361249-365445:1:exon

NP_012493.1
type: Protein
SIO_000068: ncbiprotein

S000003578
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:361249-365445:1:exon

YJL041W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: NSP1
locus tag: YJL041W
so part of: sequence
location: <365784..>368373
location: region:365784-368373:1
so has part: feature:365784-368373:1:exon
subclass of: SO_0000010

853409
type: Gene
SIO_000068: ncbigene

position:365784:1
position: 365784
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:368373:1
position: 368373
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:365784-368373:1:exon

YJL041W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: NSP1
locus tag: YJL041W
product: FG-nucleoporin NSP1
transcript id: NM_001181474.3
SIO_010081: YJL041W
subclass of: SO_0000673
so part of: YJL041W
location: join(<365784,365903..>368373)
location: region:365784-368373:1
so has part: feature:365784-365784:1:exon
so has part: feature:365903-368373:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:365784-365784:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:365903-368373:1:exon

position:365903:1
position: 365903
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YJL041W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: NSP1
locus tag: YJL041W
experiment: EXISTENCE:direct assay:GO:0005543 phospholipid binding [PMID:17897934]
experiment: EXISTENCE:direct assay:GO:0005643 nuclear pore [PMID:10684247|PMID:2112428]
experiment: EXISTENCE:direct assay:GO:0017056 structural constituent of nuclear pore [PMID:19680227|PMID:19098896]
experiment: EXISTENCE:direct assay:GO:0034399 nuclear periphery [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0044613 nuclear pore central transport channel [PMID:24574455|PMID:9813081|PMID:18046406]
experiment: EXISTENCE:direct assay:GO:0044615 nuclear pore nuclear basket [PMID:9813081]
experiment: EXISTENCE:genetic interaction:GO:0006607 NLS-bearing protein import into nucleus [PMID:15039779]
experiment: EXISTENCE:genetic interaction:GO:0016973 poly(A)+ mRNA export from nucleus [PMID:10952996]
experiment: EXISTENCE:mutant phenotype:GO:0000055 ribosomal large subunit export from nucleus [PMID:11071906|PMID:11739405|PMID:9971735]
experiment: EXISTENCE:mutant phenotype:GO:0000056 ribosomal small subunit export from nucleus [PMID:11739405]
experiment: EXISTENCE:mutant phenotype:GO:0006409 tRNA export from nucleus [PMID:8524308]
experiment: EXISTENCE:mutant phenotype:GO:0006606 protein import into nucleus [PMID:12730220|PMID:2112428]
experiment: EXISTENCE:mutant phenotype:GO:0097064 ncRNA export from nucleus [PMID:11352936]
experiment: EXISTENCE:physical interaction:GO:0017056 structural constituent of nuclear pore [PMID:12169684|PMID:17418788|PMID:19098896]
note: FG-nucleoporin component of central core of the nuclear pore complex; also part of the nuclear pore complex (NPC) nuclear basket; contributes directly to nucleocytoplasmic transport and maintenance of the NPC permeability barrier; found in stable complex with Nup82p, Gle2p and two other FG-nucleoporins (Nup159p and Nup116p); also found in stable complex with Nic96p and two other FG-nucleoproteins (Nup49p and Nup57p)
codon start: 1
product: FG-nucleoporin NSP1
translation: MNFNTPQQNKTPFSFGTANNNSNTTNQNSSTGAGAFGTGQSTFGFNNSAPNNTNNANSSITPAFGSNNTGNTAFGNSNPTSNVFGSNNSTTNTFGSNSAGTSLFGSSSAQQTKSNGTAGGNTFGSSSLFNNSTNSNTTKPAFGGLNFGGGNNTTPSSTGNANTSNNLFGATANANKPAFSFGATTNDDKKTEPDKPAFSFNSSVGNKTDAQAPTTGFSFGSQLGGNKTVNEAAKPSLSFGSGSAGANPAGASQPEPTTNEPAKPALSFGTATSDNKTTNTTPSFSFGAKSDENKAGATSKPAFSFGAKPEEKKDDNSSKPAFSFGAKSNEDKQDGTAKPAFSFGAKPAEKNNNETSKPAFSFGAKSDEKKDGDASKPAFSFGAKPDENKASATSKPAFSFGAKPEEKKDDNSSKPAFSFGAKSNEDKQDGTAKPAFSFGAKPAEKNNNETSKPAFSFGAKSDEKKDGDASKPAFSFGAKSDEKKDSDSSKPAFSFGTKSNEKKDSGSSKPAFSFGAKPDEKKNDEVSKPAFSFGAKANEKKESDESKSAFSFGSKPTGKEEGDGAKAAISFGAKPEEQKSSDTSKPAFTFGAQKDNEKKTEESSTGKSTADVKSSDSLKLNSKPVELKPVSLDNKTLDDLVTKWTNQLTESASHFEQYTKKINSWDQVLVKGGEQISQLYSDAVMAEHSQNKIDQSLQYIERQQDELENFLDNFETKTEALLSDVVSTSSGAAANNNDQKRQQAYKTAQTLDENLNSLSSNLSSLIVEINNVSNTFNKTTNIDINNEDENIQLIKILNSHFDALRSLDDNSTSLEKQINSIKK
SIO_010081: YJL041W
subclass of: SO_0000673
so part of: YJL041W
location: join(365784,365903..368373)
location: region:365784-368373:1
so has part: feature:365784-365784:1:exon
so has part: feature:365903-368373:1:exon

NP_012494.3
type: Protein
SIO_000068: ncbiprotein

S000003577
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:365784-365784:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:365903-368373:1:exon

YJL039C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: NUP192
locus tag: YJL039C
so part of: sequence
location: complement(<368748..>373799)
location: region:368748-373799:-1
so has part: feature:368748-373799:-1:exon
subclass of: SO_0000010

853410
type: Gene
SIO_000068: ncbigene

position:368748:-1
position: 368748
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:373799:-1
position: 373799
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:368748-373799:-1:exon

YJL039C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: NUP192
locus tag: YJL039C
product: Nup192p
transcript id: NM_001181473.1
SIO_010081: YJL039C
subclass of: SO_0000673
so part of: YJL039C
location: complement(<368748..>373799)
location: region:368748-373799:-1
so has part: feature:368748-373799:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:368748-373799:-1:exon

YJL039C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: NUP192
locus tag: YJL039C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005643 nuclear pore [PMID:10684247]
experiment: EXISTENCE:direct assay:GO:0044611 nuclear pore inner ring [PMID:18046406]
experiment: EXISTENCE:mutant phenotype:GO:0006999 nuclear pore organization [PMID:10428845|PMID:11121302]
experiment: EXISTENCE:mutant phenotype:GO:0017056 structural constituent of nuclear pore [PMID:10428845]
experiment: EXISTENCE:mutant phenotype:GO:0046822 regulation of nucleocytoplasmic transport [PMID:23499021]
note: Essential subunit of inner ring of nuclear pore complex (NPC); plays a role in modulating transport through the NPC; homologous to human NUP205
codon start: 1
product: Nup192p
translation: MKWSAIPFQTLYRSIESGEFDFDLFKEVLPDLQNLNLNTDKLKNNASRSQLEKGEIELSDGSTFKVNQEFIFEAISLSDELNLDEIVACELILSGDTTANNGKVQYFLRRQYILQIVSFIVNCFHEDTELYQELIKNGALVSNILSAFKFIHTQLSEIKQQINKAQILENYNALFQQNIKFRRDFLLREYDILSQILYGLVDKGAIMKNKDFILSLLHHVSELDSNDFFIIYYTPAFFHLFASLRVLPDADVKLLHSQFMKDLKDDSIYTKPVKVALIFIFFAYFIGWCKEDPKRRADTMDFKTDVDEPMTSAVELGAIEQILIFAADTSIVEQDKSMELFYDIRSLLERHIPRLIPKQLLDDEKIFSQTTNSTYNPASATDNMSGRGLWNPSYPGMMSTTGTARLNSMPNNVNEYSYTTIVLSDQTQEFFLSSFDDVLQTIITDCAFLLTKIKDAEEDSLLSGEDLTLDDISLKADLERFFLSIYFFYASRPEYSCTFWSDKESNAYGFIEWCSRCNDNLMRSCFYLMVSSLSFGPENALNVYHYFGENSSISWKNIAQCLSDYTKKISNFNSSLHKRQQFSESTHNDIDSTAVALEEGLNEEAVIFLSSLLTLVGSVTYQVDEDVKSSLSKVFSDVLFEFTKINTPLVGAAFKVISNLVPKLESSRTKFWSFLDSLIFKDSSLNYSSESYRNAFTNVLTKYSDVLGFLQLFHNLISIHSRENNSEYMVFGKLAFPTRLGQGYRKVGIWPYFDYIFNDILAHVDQIVDIRNKRAVQLPILKIIYTGLCSFDYSVILNSIPAAANLDALVDCENFFNYVQECPAIPIFNYIFTEKIYKSIFNVVDVGVDQLSIELEGGKNQAELLQLAVKIINKVLDYQETYVEELFPIVKKHGKTDYFLPKNYSLHGLRSFYDAIFFNIPLVAHLGLYVGVDDQILATNSLRILAKLSERSNGSVASLSKRNKLLTIFDSVDESARIKDAFITQLESSITDAGVLALKLELLDFLTSNLSNYSRTMTISHLLLGFQVSNVISLGPNLATFISSGTSLLDSLISVLEASLNSITKDNIDYAPMRLATAALEIILKLCRNPLTSGLLYSYLIKENFFERIMILDPQVTRFTTWNGSPFDNSTEEKCKNFIESESVGAFLSFLAYRNYWTQYLGLFIHKISFSGTKSEVLTYVNYLISNTMYSVRLFSFLDPLNYGNICEPKETLSIFTNVPLNLEQVTLNKYCSGNIYDFHKMENLMRLIKRVRAESLHSNSFSLTVSKEQFLKDADVECIKAKSHFTNIISRNKALELNLSVLHSWVQLVQIIVTDGKLEPSTRSNFILEVFGTIIPKISDYIEFNITFSEELVSLAVFLFDIYNRDRKLITDKGTVDGRLYQLFKTCIQGINSPLSSVALRSDFYILANHYLSRVLSDQVGSEKVLQDLRLGSKKLVEIIWNDVVYGEGTSRVTGILLLDSLIQLANRSKENFILDSLMKTTRLLLIIRSLKNTDALLNSTTEHINIDDLLYELTAFKATVFFLIRVAETRGGASALIENNLFRIIAELSFLKVDPDLGLDLMFDEVYVQNSKFLKVNVTLDNPLLVDKDANGVSLFELIVPIFQLISAVLVSMGSSNKAVVQTVKGLLNTYKRLVIGIFKRDLLREKEDKKNSSDPNNQSLNEMVKLIVMLCTLTGYQNND
SIO_010081: YJL039C
subclass of: SO_0000673
so part of: YJL039C
location: complement(368748..373799)
location: region:368748-373799:-1
so has part: feature:368748-373799:-1:exon

NP_012495.1
type: Protein
SIO_000068: ncbiprotein

S000003576
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:368748-373799:-1:exon

YNCJ0013C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCJ0013C
so part of: sequence
location: complement(374424..374495)
location: region:374424-374495:-1
so has part: feature:374424-374495:-1:exon
subclass of: SO_0000663

853411
type: Gene
SIO_000068: ncbigene

position:374424:-1
position: 374424
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:374495:-1
position: 374495
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:374424-374495:-1:exon

YNCJ0013C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCJ0013C
product: tRNA-Asp
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Aspartate tRNA (tRNA-Asp), predicted by tRNAscan-SE analysis
SIO_010081: YNCJ0013C
subclass of: SO_0000673
so part of: YNCJ0013C
location: complement(374424..374495)
location: region:374424-374495:-1
so has part: feature:374424-374495:-1:exon

S000006538
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:374424-374495:-1:exon

YNCJ0014C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCJ0014C
so part of: sequence
location: complement(374506..374577)
location: region:374506-374577:-1
so has part: feature:374506-374577:-1:exon
subclass of: SO_0000663

853412
type: Gene
SIO_000068: ncbigene

position:374506:-1
position: 374506
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:374577:-1
position: 374577
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:374506-374577:-1:exon

YNCJ0014C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCJ0014C
product: tRNA-Arg
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Arginine tRNA (tRNA-Arg), predicted by tRNAscan-SE analysis; one of 11 nuclear tRNA genes containing the tDNA-anticodon UCU (converted to mcm5-UCU in the mature tRNA), decodes AGA codons into arginine, one of 19 nuclear tRNAs for arginine
SIO_010081: YNCJ0014C
subclass of: SO_0000673
so part of: YNCJ0014C
location: complement(374506..374577)
location: region:374506-374577:-1
so has part: feature:374506-374577:-1:exon

S000006715
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:374506-374577:-1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(374844..374935)
location: region:374844-374935:-1
so has part: feature:374844-374935:-1:region

S000007025
type: SGD
SIO_000068: sgd

position:374844:-1
position: 374844
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:374935:-1
position: 374935
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:374844-374935:-1:region

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1012; Autonomously Replicating Sequence
so part of: sequence
location: 374880..375122
location: region:374880-375122:1
so has part: feature:374880-375122:1:region

S000028449
type: SGD
SIO_000068: sgd

position:374880:1
position: 374880
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:375122:1
position: 375122
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:374880-375122:1:region

YJL038C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: OSW4
gene: LOH1
locus tag: YJL038C
gene synonym: OSW4
so part of: sequence
location: complement(<375115..>375774)
location: region:375115-375774:-1
so has part: feature:375115-375774:-1:exon
subclass of: SO_0000010

853413
type: Gene
SIO_000068: ncbigene

position:375115:-1
position: 375115
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:375774:-1
position: 375774
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:375115-375774:-1:exon

YJL038C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: OSW4
gene: LOH1
locus tag: YJL038C
gene synonym: OSW4
product: Loh1p
transcript id: NM_001181472.1
SIO_010081: YJL038C
subclass of: SO_0000673
so part of: YJL038C
location: complement(<375115..>375774)
location: region:375115-375774:-1
so has part: feature:375115-375774:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:375115-375774:-1:exon

YJL038C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: OSW4
gene: LOH1
locus tag: YJL038C
gene synonym: OSW4
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0030476 ascospore wall assembly [PMID:23966878]
experiment: EXISTENCE:mutant phenotype:GO:0051276 chromosome organization [PMID:18562670]
note: Protein involved in outer spore wall assembly; likely involved directly in dityrosine layer assembly; induced during sporulation; repressed during vegetative growth by Sum1p and Hst1p; sequence similar to adjacent ORF, IRC18/YJL037W, and the irc18 loh1 double mutant exhibits reduced dityrosine fluorescence relative to the single mutants; SWAT-GFP and mCherry fusion proteins localize to the cytosol; proposed role in maintenance of genome integrity
codon start: 1
product: Loh1p
translation: MRFQLFIYFYFTIVVIAGTNTIQQFSDAGDRLITSLRNLDNNGTYETLTAEKVPIIEGQIQNISAKYEQHTFILKGLEAVLNYKVKSLDNNERESLEIEYEKVEKALDAALNVSPFEYIKKFKEVSRGKVVNALENLSREQNRITINGGREDEKEKEAREKKKRLDRIKRILTVSLLELGLAQGVADLCAVAPFACLLGVTVGSIGFIFWLALIYNAIQ
SIO_010081: YJL038C
subclass of: SO_0000673
so part of: YJL038C
location: complement(375115..375774)
location: region:375115-375774:-1
so has part: feature:375115-375774:-1:exon

NP_012496.1
type: Protein
SIO_000068: ncbiprotein

S000003575
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:375115-375774:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1013; Autonomously Replicating Sequence; inefficient as chromosomal replication origin; replication capacity dependent upon Sum1p
so part of: sequence
location: 375706..376227
location: region:375706-376227:1
so has part: feature:375706-376227:1:region

S000028450
type: SGD
SIO_000068: sgd

position:375706:1
position: 375706
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:376227:1
position: 376227
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:375706-376227:1:region

YJL037W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: OSW6
gene: IRC18
locus tag: YJL037W
gene synonym: OSW6
so part of: sequence
location: <376662..>377336
location: region:376662-377336:1
so has part: feature:376662-377336:1:exon
subclass of: SO_0000010

853414
type: Gene
SIO_000068: ncbigene

position:376662:1
position: 376662
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:377336:1
position: 377336
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:376662-377336:1:exon

YJL037W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: OSW6
gene: IRC18
locus tag: YJL037W
gene synonym: OSW6
product: Irc18p
transcript id: NM_001181471.3
SIO_010081: YJL037W
subclass of: SO_0000673
so part of: YJL037W
location: <376662..>377336
location: region:376662-377336:1
so has part: feature:376662-377336:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:376662-377336:1:exon

YJL037W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: OSW6
gene: IRC18
locus tag: YJL037W
gene synonym: OSW6
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0030476 ascospore wall assembly [PMID:23966878]
note: Protein involved in outer spore wall assembly; possible role in assembly of the dityrosine layer; similar to adjacent ORF, LOH1; irc18 loh1 double mutant exhibits reduced dityrosine fluorescence relative to single mutants; SWAT-GFP fusion protein localizes to the ER and vacuole, while mCherry fusion localizes to the vacuole; expression induced in respiratory-deficient cells and carbon-limited chemostat culture; null mutant displays increased levels of spontaneous Rad52p foci
codon start: 1
product: Irc18p
translation: MKVQMIERIFLIQLCLLTVVLASSRAVVEFESTGTKLVNSLRVLAAYSQSSVCVDEKISGIERQIEEVKDMYGNHSFILKGLNGILNNKVNMLTREIQMETVGNNTFETETGKLTKGLNRAVNISPFKYIKKFKTVSTKKFESLLNKYDLVAKKGGELTEEQKKKKEVLSRISRVVAATTIEAGLAQGVVDLCITVTTSLCLVSASIGGVGFLIWLTIIYQALT
SIO_010081: YJL037W
subclass of: SO_0000673
so part of: YJL037W
location: 376662..377336
location: region:376662-377336:1
so has part: feature:376662-377336:1:exon

NP_012497.3
type: Protein
SIO_000068: ncbiprotein

S000003574
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:376662-377336:1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(377598..377870)
location: region:377598-377870:-1
so has part: feature:377598-377870:-1:region

S000007026
type: SGD
SIO_000068: sgd

position:377598:-1
position: 377598
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:377870:-1
position: 377870
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:377598-377870:-1:region

YNCJ0015W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCJ0015W
so part of: sequence
location: 378360..378433
location: region:378360-378433:1
so has part: feature:378360-378433:1:exon
subclass of: SO_0000663

853415
type: Gene
SIO_000068: ncbigene

position:378360:1
position: 378360
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:378433:1
position: 378433
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:378360-378433:1:exon

YNCJ0015W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCJ0015W
product: tRNA-Val
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Valine tRNA (tRNA-Val), predicted by tRNAscan-SE analysis
SIO_010081: YNCJ0015W
subclass of: SO_0000673
so part of: YNCJ0015W
location: 378360..378433
location: region:378360-378433:1
so has part: feature:378360-378433:1:exon

S000006759
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:378360-378433:1:exon

YJL036W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ATG24
alternative label: CVT13
gene: SNX4
locus tag: YJL036W
gene synonym: ATG24; CVT13
so part of: sequence
location: <378825..>380096
location: region:378825-380096:1
so has part: feature:378825-380096:1:exon
subclass of: SO_0000010

853416
type: Gene
SIO_000068: ncbigene

position:378825:1
position: 378825
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:380096:1
position: 380096
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:378825-380096:1:exon

YJL036W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ATG24
alternative label: CVT13
gene: SNX4
locus tag: YJL036W
gene synonym: ATG24; CVT13
product: Snx4p
transcript id: NM_001181470.1
SIO_010081: YJL036W
subclass of: SO_0000673
so part of: YJL036W
location: <378825..>380096
location: region:378825-380096:1
so has part: feature:378825-380096:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:378825-380096:1:exon

YJL036W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ATG24
alternative label: CVT13
gene: SNX4
locus tag: YJL036W
gene synonym: ATG24; CVT13
experiment: EXISTENCE:direct assay:GO:0000407 phagophore assembly site [PMID:12048214|PMID:18497569]
experiment: EXISTENCE:direct assay:GO:0005769 early endosome [PMID:17420293]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:12048214|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0032266 phosphatidylinositol-3-phosphate binding [PMID:12554655|PMID:11557775]
experiment: EXISTENCE:direct assay:GO:0048471 perinuclear region of cytoplasm [PMID:33678121]
experiment: EXISTENCE:genetic interaction:GO:0034498 early endosome to Golgi transport [PMID:12554655]
experiment: EXISTENCE:genetic interaction:GO:0036010 protein localization to endosome [PMID:29511122]
experiment: EXISTENCE:mutant phenotype:GO:0000422 autophagy of mitochondrion [PMID:19793921]
experiment: EXISTENCE:mutant phenotype:GO:0006623 protein targeting to vacuole [PMID:12554655]
experiment: EXISTENCE:mutant phenotype:GO:0032258 cytoplasm to vacuole transport by the Cvt pathway [PMID:12048214|PMID:12554655]
experiment: EXISTENCE:mutant phenotype:GO:0032456 endocytic recycling [PMID:32074001]
experiment: EXISTENCE:mutant phenotype:GO:0034498 early endosome to Golgi transport [PMID:12554655]
experiment: EXISTENCE:mutant phenotype:GO:0034727 piecemeal microautophagy of the nucleus [PMID:18701704]
experiment: EXISTENCE:physical interaction:GO:0034498 early endosome to Golgi transport [PMID:12554655]
note: Sorting nexin; involved in retrieval of late-Golgi SNAREs from post-Golgi endosomes to the trans-Golgi network and in cytoplasm to vacuole transport; contains a PX phosphoinositide-binding domain; forms complexes with Snx41p and with Atg20p
codon start: 1
product: Snx4p
translation: MTDKGKNDLTSKAKDKARGNPEKPPYWFEIIVSDPQKRTGDPGSSSGYVSYQISTKTNNTSFYDNRGDPESIIVVHRRYSDLLLLHDILLNRFPTCIIPPLPDKKVFQYIAGDRFSQRFTQKRCHSLQNFLRRVSLHPDLSQSKVFKTFLVSKDWESHRKVLQDSLQPNKDEVTDAFMNAFKTVHKQNEEFTEIREKSDKLDRTVTKIDKLFHKVVKKNDSMSEDYTKLGSNLQELQELVTGENEELAAKLKIFNEGVTQLSYGLQDLTKYLDYEYIVDLKDLEHYIDSMRQLIKLKDQKQIDYEELSDYLTRSIKEKNNLISGYGGSNFFANKLEELAGINQEASRREKINKLEGKITSLTGELENAKKVADGFEQECLKEIDHFESVKTAEIKKSLGSLADHHIEFYERILEAWEKVDDSL
SIO_010081: YJL036W
subclass of: SO_0000673
so part of: YJL036W
location: 378825..380096
location: region:378825-380096:1
so has part: feature:378825-380096:1:exon

NP_012498.1
type: Protein
SIO_000068: ncbiprotein

S000003573
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:378825-380096:1:exon

YJL035C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TAD2
locus tag: YJL035C
so part of: sequence
location: complement(<380249..>381001)
location: region:380249-381001:-1
so has part: feature:380249-381001:-1:exon
subclass of: SO_0000010

853417
type: Gene
SIO_000068: ncbigene

position:380249:-1
position: 380249
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:381001:-1
position: 381001
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:380249-381001:-1:exon

YJL035C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TAD2
locus tag: YJL035C
product: tRNA(adenine34) deaminase
transcript id: NM_001181469.1
SIO_010081: YJL035C
subclass of: SO_0000673
so part of: YJL035C
location: complement(<380249..>381001)
location: region:380249-381001:-1
so has part: feature:380249-381001:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:380249-381001:-1:exon

YJL035C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TAD2
locus tag: YJL035C
EC number: 3.5.4.33
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0006400 tRNA modification [PMID:10550050]
experiment: EXISTENCE:direct assay:GO:0008251 tRNA-specific adenosine deaminase activity [PMID:10550050]
note: Subunit of tRNA-specific adenosine-34 deaminase; forms a heterodimer with Tad3p that converts adenosine to inosine at the wobble position of several tRNAs
codon start: 1
product: tRNA(adenine34) deaminase
translation: MQHIKHMRTAVRLARYALDHDETPVACIFVHTPTGQVMAYGMNDTNKSLTGVAHAEFMGIDQIKAMLGSRGVVDVFKDITLYVTVEPCIMCASALKQLDIGKVVFGCGNERFGGNGTVLSVNHDTCTLVPKNNSAAGYESIPGILRKEAIMLLRYFYVRQNERAPKPRSKSDRVLDKNTFPPMEWSKYLNEEAFIETFGDDYRTCFANKVDLSSNSVDWDLIDSHQDNIIQELEEQCKMFKFNVHKKSKV
SIO_010081: YJL035C
subclass of: SO_0000673
so part of: YJL035C
location: complement(380249..381001)
location: region:380249-381001:-1
so has part: feature:380249-381001:-1:exon

NP_012499.1
type: Protein
SIO_000068: ncbiprotein

S000003572
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:380249-381001:-1:exon

YJL034W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: GRP78
gene: KAR2
locus tag: YJL034W
gene synonym: GRP78
so part of: sequence
location: <381327..>383375
location: region:381327-383375:1
so has part: feature:381327-383375:1:exon
subclass of: SO_0000010

853418
type: Gene
SIO_000068: ncbigene

position:381327:1
position: 381327
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:383375:1
position: 383375
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:381327-383375:1:exon

YJL034W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: GRP78
gene: KAR2
locus tag: YJL034W
gene synonym: GRP78
product: Hsp70 family ATPase KAR2
transcript id: NM_001181468.3
SIO_010081: YJL034W
subclass of: SO_0000673
so part of: YJL034W
location: <381327..>383375
location: region:381327-383375:1
so has part: feature:381327-383375:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:381327-383375:1:exon

YJL034W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: GRP78
gene: KAR2
locus tag: YJL034W
gene synonym: GRP78
EC number: 3.6.4.10
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:2661018]
experiment: EXISTENCE:direct assay:GO:0016887 ATP hydrolysis activity [PMID:1325440]
experiment: EXISTENCE:direct assay:GO:0031204 post-translational protein targeting to membrane, translocation [PMID:10367885]
experiment: EXISTENCE:direct assay:GO:0034099 luminal surveillance complex [PMID:16873065]
experiment: EXISTENCE:direct assay:GO:0051082 unfolded protein binding [PMID:23704572]
experiment: EXISTENCE:genetic interaction:GO:0070880 fungal-type cell wall beta-glucan biosynthetic process [PMID:9430631]
experiment: EXISTENCE:mutant phenotype:GO:0000742 karyogamy involved in conjugation with cellular fusion [PMID:10069807]
experiment: EXISTENCE:mutant phenotype:GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation [PMID:7568189]
experiment: EXISTENCE:mutant phenotype:GO:0006986 response to unfolded protein [PMID:12808051]
experiment: EXISTENCE:mutant phenotype:GO:0030433 ubiquitin-dependent ERAD pathway [PMID:11381090]
experiment: EXISTENCE:mutant phenotype:GO:0031204 post-translational protein targeting to membrane, translocation [PMID:7568189]
experiment: EXISTENCE:mutant phenotype:GO:0051082 unfolded protein binding [PMID:12808051]
experiment: EXISTENCE:mutant phenotype:GO:0070972 protein localization to endoplasmic reticulum [PMID:1996357]
note: ATPase involved in protein import into the ER; also acts as a chaperone to mediate protein folding in the ER and may play a role in ER export of soluble proteins; regulates the unfolded protein response via interaction with Ire1p
codon start: 1
product: Hsp70 family ATPase KAR2
translation: MFFNRLSAGKLLVPLSVVLYALFVVILPLQNSFHSSNVLVRGADDVENYGTVIGIDLGTTYSCVAVMKNGKTEILANEQGNRITPSYVAFTDDERLIGDAAKNQVAANPQNTIFDIKRLIGLKYNDRSVQKDIKHLPFNVVNKDGKPAVEVSVKGEKKVFTPEEISGMILGKMKQIAEDYLGTKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVLRIVNEPTAAAIAYGLDKSDKEHQIIVYDLGGGTFDVSLLSIENGVFEVQATSGDTHLGGEDFDYKIVRQLIKAFKKKHGIDVSDNNKALAKLKREAEKAKRALSSQMSTRIEIDSFVDGIDLSETLTRAKFEELNLDLFKKTLKPVEKVLQDSGLEKKDVDDIVLVGGSTRIPKVQQLLESYFDGKKASKGINPDEAVAYGAAVQAGVLSGEEGVEDIVLLDVNALTLGIETTGGVMTPLIKRNTAIPTKKSQIFSTAVDNQPTVMIKVYEGERAMSKDNNLLGKFELTGIPPAPRGVPQIEVTFALDANGILKVSATDKGTGKSESITITNDKGRLTQEEIDRMVEEAEKFASEDASIKAKVESRNKLENYAHSLKNQVNGDLGEKLEEEDKETLLDAANDVLEWLDDNFETAIAEDFDEKFESLSKVAYPITSKLYGGADGSGAADYDDEDEDDDGDYFEHDEL
SIO_010081: YJL034W
subclass of: SO_0000673
so part of: YJL034W
location: 381327..383375
location: region:381327-383375:1
so has part: feature:381327-383375:1:exon

NP_012500.3
type: Protein
SIO_000068: ncbiprotein

S000003571
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:381327-383375:1:exon

YJL033W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: DBP4
alternative label: ECM24
gene: HCA4
locus tag: YJL033W
gene synonym: DBP4; ECM24
so part of: sequence
location: <383837..>386149
location: region:383837-386149:1
so has part: feature:383837-386149:1:exon
subclass of: SO_0000010

853419
type: Gene
SIO_000068: ncbigene

position:383837:1
position: 383837
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:386149:1
position: 386149
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:383837-386149:1:exon

YJL033W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: DBP4
alternative label: ECM24
gene: HCA4
locus tag: YJL033W
gene synonym: DBP4; ECM24
product: RNA-dependent ATPase HCA4
transcript id: NM_001181467.1
SIO_010081: YJL033W
subclass of: SO_0000673
so part of: YJL033W
location: <383837..>386149
location: region:383837-386149:1
so has part: feature:383837-386149:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:383837-386149:1:exon

YJL033W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: DBP4
alternative label: ECM24
gene: HCA4
locus tag: YJL033W
gene synonym: DBP4; ECM24
EC number: 3.6.4.13
experiment: EXISTENCE:curator inference:GO:0005730 nucleolus [PMID:16209945]
experiment: EXISTENCE:direct assay:GO:0003724 RNA helicase activity [PMID:23153376]
experiment: EXISTENCE:direct assay:GO:0008186 ATP-dependent activity, acting on RNA [PMID:18975973|PMID:23153376]
experiment: EXISTENCE:direct assay:GO:0034511 U3 snoRNA binding [PMID:25535329]
experiment: EXISTENCE:direct assay:GO:0034512 box C/D RNA binding [PMID:25535329]
experiment: EXISTENCE:mutant phenotype:GO:0003724 RNA helicase activity [PMID:16209945]
experiment: EXISTENCE:mutant phenotype:GO:0006364 rRNA processing [PMID:16209945]
experiment: EXISTENCE:mutant phenotype:GO:0032040 small-subunit processome [PMID:24357410]
note: DEAD box RNA helicase; component of the SSU; interacts with Bfr2p and Enp2p; high-copy number suppression of a U14 snoRNA processing mutant suggests an involvement in 18S rRNA synthesis
codon start: 1
product: RNA-dependent ATPase HCA4
translation: MAKKNRLNTTQRKTLRQKEDEYIENLKTKIDEYDPKITKAKFFKDLPISDPTLKGLRESSFIKLTEIQADSIPVSLQGHDVLAAAKTGSGKTLAFLVPVIEKLYREKWTEFDGLGALIISPTRELAMQIYEVLTKIGSHTSFSAGLVIGGKDVKFELERISRINILIGTPGRILQHLDQAVGLNTSNLQMLVLDEADRCLDMGFKKTLDAIVSTLSPSRQTLLFSATQSQSVADLARLSLTDYKTVGTHDVMDGSVNKEASTPETLQQFYIEVPLADKLDILFSFIKSHLKCKMIVFLSSSKQVHFVYETFRKMQPGISLMHLHGRQKQRARTETLDKFNRAQQVCLFATDVVARGIDFPAVDWVVQVDCPEDVDTYIHRVGRCARYGKKGKSLIMLTPQEQEAFLKRLNARKIEPGKLNIKQSKKKSIKPQLQSLLFKDPELKYLGQKAFISYVRSIYVQKDKQVFKFDELPTEEFAYSLGLPGAPKIKMKGMKTIEQAKERKNAPRQLAFLSKANEDGEVIEDKSKQPRTKYDKMFERKNQTILSEHYLNITKAQAQEDEDDDFISVKRKDHEINEAELPALTLPTSRRAQKKALSKKASLASKGNASKLIFDDEGEAHPVYELEDEEEFHKRGDAEVQKTEFLTKESAVMADIDNIDKQVAKEKKQEKKRKRLEAMRREMEAAMEEEISGDEEEGKTVAYLGTGNLSDDMSDGDMPDSEGHLKKKARTVDYSHGHNPSNSVDDDIIEVEEPQTLEDLESLTAKLIQG
SIO_010081: YJL033W
subclass of: SO_0000673
so part of: YJL033W
location: 383837..386149
location: region:383837-386149:1
so has part: feature:383837-386149:1:exon

NP_012501.1
type: Protein
SIO_000068: ncbiprotein

S000003570
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:383837-386149:1:exon

YJL031C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: BET4
locus tag: YJL031C
so part of: sequence
location: complement(<386368..>387438)
location: region:386368-387438:-1
so has part: feature:386368-387438:-1:exon
subclass of: SO_0000010

853421
type: Gene
SIO_000068: ncbigene

position:386368:-1
position: 386368
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:387438:-1
position: 387438
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:386368-387438:-1:exon

YJL031C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: BET4
locus tag: YJL031C
product: Rab geranylgeranyltransferase BET4
transcript id: NM_001181465.1
SIO_010081: YJL031C
subclass of: SO_0000673
so part of: YJL031C
location: complement(join(<386368..387348,387436..>387438))
location: region:386368-387438:-1
so has part: feature:387436-387438:-1:exon
so has part: feature:386368-387348:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:387436-387438:-1:exon

position:387436:-1
position: 387436
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:386368-387348:-1:exon

position:387348:-1
position: 387348
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YJL031C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: BET4
locus tag: YJL031C
EC number: 2.5.1.60
experiment: EXISTENCE:direct assay:GO:0004663 Rab geranylgeranyltransferase activity [PMID:8756702]
experiment: EXISTENCE:direct assay:GO:0005777 peroxisome [PMID:27663510]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005968 Rab-protein geranylgeranyltransferase complex [PMID:8756702]
experiment: EXISTENCE:direct assay:GO:0018344 protein geranylgeranylation [PMID:8756702]
experiment: EXISTENCE:mutant phenotype:GO:0006612 protein targeting to membrane [PMID:8232541]
experiment: EXISTENCE:mutant phenotype:GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport [PMID:8232541]
experiment: EXISTENCE:mutant phenotype:GO:0018344 protein geranylgeranylation [PMID:8232541]
experiment: EXISTENCE:physical interaction:GO:0005968 Rab-protein geranylgeranyltransferase complex [PMID:8232542]
note: Alpha subunit of Type II geranylgeranyltransferase; required for vesicular transport between the endoplasmic reticulum and the Golgi; provides a membrane attachment moiety to Rab-like proteins Ypt1p and Sec4p
codon start: 1
product: Rab geranylgeranyltransferase BET4
translation: MHGIKRKQWTKELLRQKRVQDEKKIYDYRSLTENVLNMRDEKIYSIEALKKTSELLEKNPEFNAIWNYRRDIIASLASELEIPFWDKELVFVMMLLKDYPKVYWIWNHRLWVLKHYPTSSPKVWQTELAVVNKLLEQDARNYHGWHYRRIVVGNIESITNKSLDKEEFEYTTIKINNNISNYSAWHQRVQIISRMFQKGEVGNQKEYIRTEISYIINAMFTDAEDQSVWFYIKWFIKNDIVCKTLDEQEYLKMLKDLRENILLINNDEIEFSGKQNIWCLKILLVLEDILEEKEALTERSSEQYLVQLIDADPLRKNRYLHLLEQHK
SIO_010081: YJL031C
subclass of: SO_0000673
so part of: YJL031C
location: complement(join(386368..387348,387436..387438))
location: region:386368-387438:-1
so has part: feature:387436-387438:-1:exon
so has part: feature:386368-387348:-1:exon

NP_012503.2
type: Protein
SIO_000068: ncbiprotein

S000003568
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:387436-387438:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:386368-387348:-1:exon

YJL030W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MAD2
locus tag: YJL030W
so part of: sequence
location: <387657..>388247
location: region:387657-388247:1
so has part: feature:387657-388247:1:exon
subclass of: SO_0000010

853422
type: Gene
SIO_000068: ncbigene

position:387657:1
position: 387657
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:388247:1
position: 388247
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:387657-388247:1:exon

YJL030W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MAD2
locus tag: YJL030W
product: spindle checkpoint protein MAD2
transcript id: NM_001181464.3
SIO_010081: YJL030W
subclass of: SO_0000673
so part of: YJL030W
location: <387657..>388247
location: region:387657-388247:1
so has part: feature:387657-388247:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:387657-388247:1:exon

YJL030W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MAD2
locus tag: YJL030W
experiment: EXISTENCE:direct assay:GO:0000776 kinetochore [PMID:27170178]
experiment: EXISTENCE:direct assay:GO:0033597 mitotic checkpoint complex [PMID:11726501]
experiment: EXISTENCE:direct assay:GO:0044877 protein-containing complex binding [PMID:12473689]
experiment: EXISTENCE:direct assay:GO:1902499 positive regulation of protein autoubiquitination [PMID:22940250]
experiment: EXISTENCE:genetic interaction:GO:0044774 mitotic DNA integrity checkpoint signaling [PMID:16651657]
experiment: EXISTENCE:mutant phenotype:GO:0007094 mitotic spindle assembly checkpoint signaling [PMID:10704439]
experiment: EXISTENCE:mutant phenotype:GO:0051312 chromosome decondensation [PMID:17151360]
experiment: EXISTENCE:physical interaction:GO:0007094 mitotic spindle assembly checkpoint signaling [PMID:9461437]
experiment: EXISTENCE:physical interaction:GO:0033597 mitotic checkpoint complex [PMID:10704439|PMID:11726501]
note: Component of the spindle-assembly checkpoint complex; delays onset of anaphase in cells with defects in mitotic spindle assembly; forms a complex with Mad1p; regulates APC/C activity during prometaphase and metaphase of meiosis I; gene dosage imbalance between MAD1 and MAD2 leads to chromosome instability
codon start: 1
product: spindle checkpoint protein MAD2
translation: MSQSISLKGSTRTVTEFFEYSINSILYQRGVYPAEDFVTVKKYDLTLLKTHDDELKDYIRKILLQVHRWLLGGKCNQLVLCIVDKDEGEVVERWSFNVQHISGNSNGQDDVVDLNTTQSQIRALIRQITSSVTFLPELTKEGGYTFTVLAYTDADAKVPLEWADSNSKEIPDGEVVQFKTFSTNDHKVGAQVSYKY
SIO_010081: YJL030W
subclass of: SO_0000673
so part of: YJL030W
location: 387657..388247
location: region:387657-388247:1
so has part: feature:387657-388247:1:exon

NP_012504.3
type: Protein
SIO_000068: ncbiprotein

S000003567
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:387657-388247:1:exon

YJL029C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: VPS53
locus tag: YJL029C
so part of: sequence
location: complement(<388385..>390853)
location: region:388385-390853:-1
so has part: feature:388385-390853:-1:exon
subclass of: SO_0000010

853423
type: Gene
SIO_000068: ncbigene

position:388385:-1
position: 388385
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:390853:-1
position: 390853
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:388385-390853:-1:exon

YJL029C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: VPS53
locus tag: YJL029C
product: Vps53p
transcript id: NM_001181463.1
SIO_010081: YJL029C
subclass of: SO_0000673
so part of: YJL029C
location: complement(<388385..>390853)
location: region:388385-390853:-1
so has part: feature:388385-390853:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:388385-390853:-1:exon

YJL029C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: VPS53
locus tag: YJL029C
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005794 Golgi apparatus [PMID:10637310]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0042147 retrograde transport, endosome to Golgi [PMID:12686613]
experiment: EXISTENCE:mutant phenotype:GO:0006896 Golgi to vacuole transport [PMID:10637310]
experiment: EXISTENCE:mutant phenotype:GO:0090156 cellular sphingolipid homeostasis [PMID:26357016]
experiment: EXISTENCE:physical interaction:GO:0000938 GARP complex [PMID:10637310]
note: Component of the GARP (Golgi-associated retrograde protein) complex; GARP is required for the recycling of proteins from endosomes to the late Golgi, and for mitosis after DNA damage induced checkpoint arrest; required for vacuolar protein sorting; members of the GARP complex are Vps51p-Vps52p-Vps53p-Vps54p; human ortholog is implicated in progressive cerebello-cerebral atrophy type 2 (PCCA2)
codon start: 1
product: Vps53p
translation: MLEGTVDYDPLEDITNILFSKESLNNIDELISITRSYKKQLQEDILKEENELKEHPKNSAEIEASLRKVFQDFKETQDVSASTELTISNLTEGISYLDIAKKNLTHSLTLFQNLKILTDSYIQCNELLSQGSFKKMVSPYKIMCSLAENTFISYKSLDEINYLLSSISRLKGDTLSKIKQNYNALFSGGNISEHDTALTMELREGACELLDCDTSTRAQMIDWCLDKLLFEMKEIFRVDDEAGSLENLSRRYIYFKKILNNFNSKFADYFLKDWEMAVRLTTTFYHITHKDLQTLLKREFKDKNPSIDLFMTALQSTLDFEKYIDVRFSKKIKEPKLSSCFEPYLTLWVSHQNQMMEKKFLSYMSEPKYPSNETESLVLPSSADLFRTYRSVLTQTLELIDNNANDSILTSLANFFSRWLQTYSQKILLPLLLPDNIEVQDKLEAAKYTVLLINTADYCATTIDQLEDKLSEFSGNREKLANSFTKTKNIYDDLLAKGTSFLLNRVIPLDLNFVWREFINNDWSNAAIEDYSRYMVTLKSVLKMPALTDASIKQQQEQPSTLAFILSQFNRDVYKWNFLDKVIDIITTNFVSNTIRLLQPVPPFSLAGSKRKFETRTVVNIGEQLLLDLELLKEIFHTLPESVSNDSDLRENTSYKRVKRHADNNIDQLLKFIKLLMAPLDSADDYYETYSKLTNNNPDSAVWSFVLALKGIPWDLALWKKLWSAYNLETDDTDEGSRPDSNRDLFIFKWDKVLLGQFENNLARMQDPNWSKFVRQDLKISPPVMKRIVSTPQIQQQKEEQKKQSLSVKDFVSHSRFFNRGT
SIO_010081: YJL029C
subclass of: SO_0000673
so part of: YJL029C
location: complement(388385..390853)
location: region:388385-390853:-1
so has part: feature:388385-390853:-1:exon

NP_012505.1
type: Protein
SIO_000068: ncbiprotein

S000003566
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:388385-390853:-1:exon

YNCJ0016C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: EMT5
locus tag: YNCJ0016C
so part of: sequence
location: complement(391043..391115)
location: region:391043-391115:-1
so has part: feature:391043-391115:-1:exon
subclass of: SO_0000663

853424
type: Gene
SIO_000068: ncbigene

position:391043:-1
position: 391043
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:391115:-1
position: 391115
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:391043-391115:-1:exon

YNCJ0016C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
gene: EMT5
locus tag: YNCJ0016C
product: tRNA-Met
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Methionine tRNA (tRNA-Met), functions in translational elongation; not involved in translational initiation; predicted by tRNAscan-SE analysis
SIO_010081: YNCJ0016C
subclass of: SO_0000673
so part of: YNCJ0016C
location: complement(391043..391115)
location: region:391043-391115:-1
so has part: feature:391043-391115:-1:exon

S000006661
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:391043-391115:-1:exon

YJL028W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJL028W
so part of: sequence
location: <391311..>391646
location: region:391311-391646:1
so has part: feature:391311-391646:1:exon
subclass of: SO_0000010

853425
type: Gene
SIO_000068: ncbigene

position:391311:1
position: 391311
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:391646:1
position: 391646
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:391311-391646:1:exon

YJL028W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJL028W
product: uncharacterized protein
transcript id: NM_001181462.1
SIO_010081: YJL028W
subclass of: SO_0000673
so part of: YJL028W
location: <391311..>391646
location: region:391311-391646:1
so has part: feature:391311-391646:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:391311-391646:1:exon

YJL028W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJL028W
note: hypothetical protein; may interact with ribosomes, based on co-purification experiments
codon start: 1
product: uncharacterized protein
translation: MALWGRSAYRQKTVTSRLTKHRHTSPLNLLNFFIFFSLHLCALFLATAVHYACFACFVLFRHAILLLFYLLARGRASQIQARQKVRCTGATFYRFLIISLSQRAWATKKPI
SIO_010081: YJL028W
subclass of: SO_0000673
so part of: YJL028W
location: 391311..391646
location: region:391311-391646:1
so has part: feature:391311-391646:1:exon

NP_012506.1
type: Protein
SIO_000068: ncbiprotein

S000003565
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:391311-391646:1:exon

YJL027C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJL027C
so part of: sequence
location: complement(<391833..>392249)
location: region:391833-392249:-1
so has part: feature:391833-392249:-1:exon
subclass of: SO_0000010

853426
type: Gene
SIO_000068: ncbigene

position:391833:-1
position: 391833
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:392249:-1
position: 392249
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:391833-392249:-1:exon

YJL027C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJL027C
product: uncharacterized protein
transcript id: NM_001181461.3
SIO_010081: YJL027C
subclass of: SO_0000673
so part of: YJL027C
location: complement(<391833..>392249)
location: region:391833-392249:-1
so has part: feature:391833-392249:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:391833-392249:-1:exon

YJL027C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJL027C
codon start: 1
product: uncharacterized protein
translation: MMVTRKHYRYIYLQNSHSLISCFVHFEFPRVWYGAICPCFPSFALLRKIFFCQQQQHATLCAVLRSGLCGNGDIVPMPARREVWVWGVCDLVAMAIARGCGLSPNGCPLLRISHSCRVNKKHERGRTALNSGRSRDVK
SIO_010081: YJL027C
subclass of: SO_0000673
so part of: YJL027C
location: complement(391833..392249)
location: region:391833-392249:-1
so has part: feature:391833-392249:-1:exon

NP_012507.3
type: Protein
SIO_000068: ncbiprotein

S000003564
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:391833-392249:-1:exon

YJL026W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CRT6
gene: RNR2
locus tag: YJL026W
gene synonym: CRT6
so part of: sequence
location: <392404..>393603
location: region:392404-393603:1
so has part: feature:392404-393603:1:exon
subclass of: SO_0000010

853427
type: Gene
SIO_000068: ncbigene

position:392404:1
position: 392404
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:393603:1
position: 393603
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:392404-393603:1:exon

YJL026W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CRT6
gene: RNR2
locus tag: YJL026W
gene synonym: CRT6
product: ribonucleotide-diphosphate reductase subunit RNR2
transcript id: NM_001181460.1
SIO_010081: YJL026W
subclass of: SO_0000673
so part of: YJL026W
location: <392404..>393603
location: region:392404-393603:1
so has part: feature:392404-393603:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:392404-393603:1:exon

YJL026W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CRT6
gene: RNR2
locus tag: YJL026W
gene synonym: CRT6
EC number: 1.17.4.1
experiment: EXISTENCE:direct assay:GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [PMID:10535923|PMID:10716984]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:12732713]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:12732713|PMID:9315670]
experiment: EXISTENCE:direct assay:GO:0005971 ribonucleoside-diphosphate reductase complex [PMID:10716984]
experiment: EXISTENCE:direct assay:GO:0009263 deoxyribonucleotide biosynthetic process [PMID:10535923|PMID:5459124]
note: Ribonucleotide-diphosphate reductase (RNR), small subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits; RNR2 has a paralog, RNR4, that arose from the whole genome duplication
codon start: 1
product: ribonucleotide-diphosphate reductase subunit RNR2
translation: MPKETPSKAAADALSDLEIKDSKSNLNKELETLREENRVKSDMLKEKLSKDAENHKAYLKSHQVHRHKLKEMEKEEPLLNEDKERTVLFPIKYHEIWQAYKRAEASFWTAEEIDLSKDIHDWNNRMNENERFFISRVLAFFAASDGIVNENLVENFSTEVQIPEAKSFYGFQIMIENIHSETYSLLIDTYIKDPKESEFLFNAIHTIPEIGEKAEWALRWIQDADALFGERLVAFASIEGVFFSGSFASIFWLKKRGMMPGLTFSNELICRDEGLHTDFACLLFAHLKNKPDPAIVEKIVTEAVEIEQRYFLDALPVALLGMNADLMNQYVEFVADRLLVAFGNKKYYKVENPFDFMENISLAGKTNFFEKRVSDYQKAGVMSKSTKQEAGAFTFNEDF
SIO_010081: YJL026W
subclass of: SO_0000673
so part of: YJL026W
location: 392404..393603
location: region:392404-393603:1
so has part: feature:392404-393603:1:exon

NP_012508.1
type: Protein
SIO_000068: ncbiprotein

S000003563
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:392404-393603:1:exon

YJL025W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RRN7
locus tag: YJL025W
so part of: sequence
location: <393967..>395511
location: region:393967-395511:1
so has part: feature:393967-395511:1:exon
subclass of: SO_0000010

853428
type: Gene
SIO_000068: ncbigene

position:393967:1
position: 393967
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:395511:1
position: 395511
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:393967-395511:1:exon

YJL025W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RRN7
locus tag: YJL025W
product: Rrn7p
transcript id: NM_001181459.1
SIO_010081: YJL025W
subclass of: SO_0000673
so part of: YJL025W
location: <393967..>395511
location: region:393967-395511:1
so has part: feature:393967-395511:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:393967-395511:1:exon

YJL025W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RRN7
locus tag: YJL025W
experiment: EXISTENCE:curator inference:GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding []
experiment: EXISTENCE:direct assay:GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding [PMID:18451108]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:22362748]
experiment: EXISTENCE:direct assay:GO:0017025 TBP-class protein binding [PMID:8702872]
experiment: EXISTENCE:direct assay:GO:0042790 nucleolar large rRNA transcription by RNA polymerase I [PMID:7958901]
experiment: EXISTENCE:direct assay:GO:0070860 RNA polymerase I core factor complex [PMID:7958901|PMID:8702872|PMID:8887672]
experiment: EXISTENCE:mutant phenotype:GO:0042790 nucleolar large rRNA transcription by RNA polymerase I [PMID:7958901]
experiment: EXISTENCE:physical interaction:GO:0017025 TBP-class protein binding [PMID:8702872]
note: Component of the core factor (CF) rDNA transcription factor complex; CF is required for transcription of 35S rRNA genes by RNA polymerase I and is composed of Rrn6p, Rrn7p, and Rrn11p
codon start: 1
product: Rrn7p
translation: MSTFIRGPICGTDNCPSRLWRIIDGRRTCQYGHVMEGDVEFNDDEDDLNGLGAGVITRRLNLTTNATGSFQSSQLTNSQLLQQQQRQSHKKFKKLIGHEAKLLFLKSFQFILKRQIRWLITEMRFPKEFEHVAKIIWLKILKTINDQPQEELKLQLHMTSTISILYLASTHLSLPVYTCDYIKWICTAKMPYFQASEILPKSWRIQLPNYYVSILEGSISPFNGQLYNKIALTCGMIHFKEFFNSEISCQGLLLKLVMQCALPPEFYFYTKQVIEFEETDIRNLTLWERTDERHTGRVSNHAELRVLSYFMLTINWMLSFDRDRQYPLKWILSLTESLTQRTTTSESIGRNIVKVVYPDKPTSSDYFQWSEEETLEFLKWMEKQFLPTQTKSLHNENGSMEMTIDQKIARRKLYKIFPLDREANHDGEFNDSTHQLTFIEDLQERYAKQTPFFESNKIRDSLNYQEANPPARKEAIGRLLTHIASQLLVDFAISKEQLKDCISRIKNACLHRMN
SIO_010081: YJL025W
subclass of: SO_0000673
so part of: YJL025W
location: 393967..395511
location: region:393967-395511:1
so has part: feature:393967-395511:1:exon

NP_012509.1
type: Protein
SIO_000068: ncbiprotein

S000003562
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:393967-395511:1:exon

YJL024C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YKS7
gene: APS3
locus tag: YJL024C
gene synonym: YKS7
so part of: sequence
location: complement(<395931..>396592)
location: region:395931-396592:-1
so has part: feature:395931-396592:-1:exon
subclass of: SO_0000010

853429
type: Gene
SIO_000068: ncbigene

position:395931:-1
position: 395931
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:396592:-1
position: 396592
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:395931-396592:-1:exon

YJL024C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YKS7
gene: APS3
locus tag: YJL024C
gene synonym: YKS7
product: Aps3p
transcript id: NM_001181458.3
SIO_010081: YJL024C
subclass of: SO_0000673
so part of: YJL024C
location: complement(join(<395931..396493,396571..>396592))
location: region:395931-396592:-1
so has part: feature:396571-396592:-1:exon
so has part: feature:395931-396493:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:396571-396592:-1:exon

position:396571:-1
position: 396571
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:395931-396493:-1:exon

position:396493:-1
position: 396493
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YJL024C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YKS7
gene: APS3
locus tag: YJL024C
gene synonym: YKS7
experiment: EXISTENCE:mutant phenotype:GO:0006623 protein targeting to vacuole [PMID:17895371]
experiment: EXISTENCE:mutant phenotype:GO:0006896 Golgi to vacuole transport [PMID:9335339]
experiment: EXISTENCE:mutant phenotype:GO:0030123 AP-3 adaptor complex [PMID:9250663]
note: Small subunit of the clathrin-associated adaptor complex AP-3; involved in vacuolar protein sorting; related to the sigma subunit of the mammalian clathrin AP-3 complex; suppressor of loss of casein kinase 1 function; protein abundance increases in response to DNA replication stress
codon start: 1
product: Aps3p
translation: MIHAVLIFNKKCQPRLVKFYTPVDLPKQKLLLEQVYELISQRNSDFQSSFLVTPPSLLLSNENNNDEVNNEDIQIIYKNYATLYFTFIVDDQESELAILDLIQTFVESLDRCFTEVNELDLIFNWQTLESVLEEIVQGGMVIETNVNRIVASVDELNKAAESTDSKIGRLTSTGFGSALQAFAQGGFAQWATGQ
SIO_010081: YJL024C
subclass of: SO_0000673
so part of: YJL024C
location: complement(join(395931..396493,396571..396592))
location: region:395931-396592:-1
so has part: feature:396571-396592:-1:exon
so has part: feature:395931-396493:-1:exon

NP_012510.3
type: Protein
SIO_000068: ncbiprotein

S000003561
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:396571-396592:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:395931-396493:-1:exon

YNCJ0017C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCJ0017C
so part of: sequence
location: complement(396726..396796)
location: region:396726-396796:-1
so has part: feature:396726-396796:-1:exon
subclass of: SO_0000663

853430
type: Gene
SIO_000068: ncbigene

position:396726:-1
position: 396726
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:396796:-1
position: 396796
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:396726-396796:-1:exon

YNCJ0017C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCJ0017C
product: tRNA-Gly
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
experiment: EXISTENCE:direct assay:GO:0030371 translation repressor activity [PMID:27609601]
experiment: EXISTENCE:direct assay:GO:0043022 ribosome binding [PMID:27609601]
experiment: EXISTENCE:direct assay:GO:0043555 regulation of translation in response to stress [PMID:27609601]
note: Glycine tRNA (tRNA-Gly), predicted by tRNAscan-SE analysis
SIO_010081: YNCJ0017C
subclass of: SO_0000673
so part of: YNCJ0017C
location: complement(396726..396796)
location: region:396726-396796:-1
so has part: feature:396726-396796:-1:exon

S000006583
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:396726-396796:-1:exon

YJL023C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PET130
locus tag: YJL023C
so part of: sequence
location: complement(<397355..>398398)
location: region:397355-398398:-1
so has part: feature:397355-398398:-1:exon
subclass of: SO_0000010

853432
type: Gene
SIO_000068: ncbigene

position:397355:-1
position: 397355
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:398398:-1
position: 398398
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:397355-398398:-1:exon

YJL023C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PET130
locus tag: YJL023C
product: Pet130p
transcript id: NM_001181457.1
SIO_010081: YJL023C
subclass of: SO_0000673
so part of: YJL023C
location: complement(<397355..>398398)
location: region:397355-398398:-1
so has part: feature:397355-398398:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:397355-398398:-1:exon

YJL023C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PET130
locus tag: YJL023C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0099617 matrix side of mitochondrial inner membrane [PMID:30759361]
experiment: EXISTENCE:mutant phenotype:GO:0097745 mitochondrial tRNA 5'-end processing [PMID:30759361]
note: hypothetical protein; required for efficient 5' processing of mitochondrial tRNAs, for respiratory growth and mitochondrial genome maintenance; localizes to the matrix side of the inner mitochondrial membrane
codon start: 1
product: Pet130p
translation: MKIFSTLLSQKPKGKLVIRPSTTIHSSDPFSKFIVTKNTEPLSLGDLRKSDSGNSAVCLNAENTILSTLTDLQKEEERNWDPVKFVAGKLRGVISPIQAYVTIGKKFSPNSLVYTSRFFQLHYFPEDHFMSCFRKSKPAITVKSNKKFYLNGKVFNKDKEYFNETRISKANEVELSKIQTAMTRLTNRHRNSIPSEFAYLRRDLKLKVKTTFIKEWCKLNGDKAIREYVNLNRSPNINPASMKGKPKKSFLDNLGRSTVGTAKDGYYLYIVSIFPDKDMLGEFNDEVNRSVQKVANLDWDGFLTPKKGTKGKNWVESFNDSINVQTINKILEINKFPFELRREQTEG
SIO_010081: YJL023C
subclass of: SO_0000673
so part of: YJL023C
location: complement(397355..398398)
location: region:397355-398398:-1
so has part: feature:397355-398398:-1:exon

NP_012511.1
type: Protein
SIO_000068: ncbiprotein

S000003560
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:397355-398398:-1:exon

YJL020C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MTI1
alternative label: YJL021C
gene: BBC1
locus tag: YJL020C
gene synonym: MTI1; YJL021C
so part of: sequence
location: complement(<398937..>402410)
location: region:398937-402410:-1
so has part: feature:398937-402410:-1:exon
subclass of: SO_0000010

853433
type: Gene
SIO_000068: ncbigene

position:398937:-1
position: 398937
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:402410:-1
position: 402410
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:398937-402410:-1:exon

YJL020C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MTI1
alternative label: YJL021C
gene: BBC1
locus tag: YJL020C
gene synonym: MTI1; YJL021C
product: Bbc1p
transcript id: NM_001181454.1
SIO_010081: YJL020C
subclass of: SO_0000673
so part of: YJL020C
location: complement(<398937..>402410)
location: region:398937-402410:-1
so has part: feature:398937-402410:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:398937-402410:-1:exon

YJL020C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MTI1
alternative label: YJL021C
gene: BBC1
locus tag: YJL020C
gene synonym: MTI1; YJL021C
experiment: EXISTENCE:direct assay:GO:0030479 actin cortical patch [PMID:11743162|PMID:16824951]
experiment: EXISTENCE:direct assay:GO:0032032 myosin I tail binding [PMID:11901111]
experiment: EXISTENCE:direct assay:GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation [PMID:12814545]
experiment: EXISTENCE:genetic interaction:GO:0030036 actin cytoskeleton organization [PMID:11901111]
experiment: EXISTENCE:physical interaction:GO:0032032 myosin I tail binding [PMID:11901111]
note: Protein possibly involved in assembly of actin patches; interacts with an actin assembly factor Las17p and with the SH3 domains of Type I myosins Myo3p and Myo5p; localized predominantly to cortical actin patches
codon start: 1
product: Bbc1p
translation: MSEPEVPFKVVAQFPYKSDYEDDLNFEKDQEIIVTSVEDAEWYFGEYQDSNGDVIEGIFPKSFVAVQGSEVGKEAESSPNTGSTEQRTIQPEVEQKDLPEPISPETKKETLSGPVPVPAATVPVPAATVPVPAATAVSAQVQHDSSSGNGERKVPMDSPKLKARLSMFNQDITEQVPLPKSTHLDLENIPVKKTIVADAPKYYVPPGIPTNDTSNLERKKSLKENEKKIVPEPINRAQVESGRIETENDQLKKDLPQMSLKERIALLQEQQRLQAAREEELLRKKAKLEQEHERSAVNKNEPYTETEEAEENEKTEPKPEFTPETEHNEEPQMELLAHKEITKTSREADEGTNDIEKEQFLDEYTKENQKVEESQADEARGENVAEESEIGYGHEDREGDNDEEKEEEDSEENRRAALRERMAKLSGASRFGAPVGFNPFGMASGVGNKPSEEPKKKQHKEKEEEEPEQLQELPRAIPVMPFVDPSSNPFFRKSNLSEKNQPTETKTLDPHATTEHEQKQEHGTHAYHNLAAVDNAHPEYSDHDSDEDTDDHEFEDANDGLRKHSMVEQAFQIGNNESENVNSGEKIYPQEPPISHRTAEVSHDIENSSQNTTGNVLPVSSPQTRVARNGSINSLTKSISGENRRKSINEYHDTVSTNSSALTETAQDISMAAPAAPVLSKVSHPEDKVPPHPVPSAPSAPPVPSAPSVPSAPPVPPAPPALSAPSVPPVPPVPPVSSAPPALSAPSIPPVPPTPPAPPAPPAPLALPKHNEVEEHVKSSAPLPPVSEEYHPMPNTAPPLPRAPPVPPATFEFDSEPTATHSHTAPSPPPHQNVTASTPSMMSTQQRVPTSVLSGAEKESRTLPPHVPSLTNRPVDSFHESDTTPKVASIRRSTTHDVGEISNNVKIEFNAQERWWINKSAPPAISNLKLNFLMEIDDHFISKRLHQKWVVRDFYFLFENYSQLRFSLTFNSTSPEKTVTTLQERFPSPVETQSARILDEYAQRFNAKVVEKSHSLINSHIGAKNFVSQIVSEFKDEVIQPIGARTFGATILSYKPEEGIEQLMKSLQKIKPGDILVIRKAKFEAHKKIGKNEIINVGMDSAAPYSSVVTDYDFTKNKFRVIENHEGKIIQNSYKLSHMKSGKLKVFRIVARGYVGW
SIO_010081: YJL020C
subclass of: SO_0000673
so part of: YJL020C
location: complement(398937..402410)
location: region:398937-402410:-1
so has part: feature:398937-402410:-1:exon

NP_012514.2
type: Protein
SIO_000068: ncbiprotein

S000003557
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:398937-402410:-1:exon

YJL019W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: NEP98
alternative label: YJL018W
gene: MPS3
locus tag: YJL019W
gene synonym: NEP98; YJL018W
so part of: sequence
location: <402897..>404945
location: region:402897-404945:1
so has part: feature:402897-404945:1:exon
subclass of: SO_0000010

853434
type: Gene
SIO_000068: ncbigene

position:402897:1
position: 402897
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:404945:1
position: 404945
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:402897-404945:1:exon

YJL019W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: NEP98
alternative label: YJL018W
gene: MPS3
locus tag: YJL019W
gene synonym: NEP98; YJL018W
product: Mps3p
transcript id: NM_001181453.3
SIO_010081: YJL019W
subclass of: SO_0000673
so part of: YJL019W
location: <402897..>404945
location: region:402897-404945:1
so has part: feature:402897-404945:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:402897-404945:1:exon

YJL019W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: NEP98
alternative label: YJL018W
gene: MPS3
locus tag: YJL019W
gene synonym: NEP98; YJL018W
experiment: EXISTENCE:direct assay:GO:0000781 chromosome, telomeric region [PMID:17495028]
experiment: EXISTENCE:direct assay:GO:0005635 nuclear envelope [PMID:17495028]
experiment: EXISTENCE:direct assay:GO:0005816 spindle pole body [PMID:16923827]
experiment: EXISTENCE:direct assay:GO:0005825 half bridge of spindle pole body [PMID:12486115]
experiment: EXISTENCE:direct assay:GO:0016020 membrane [PMID:12493774|PMID:12486115]
experiment: EXISTENCE:direct assay:GO:0034399 nuclear periphery [PMID:18039933|PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0007129 homologous chromosome pairing at meiosis [PMID:17495028]
experiment: EXISTENCE:genetic interaction:GO:0045141 meiotic telomere clustering [PMID:17495028]
experiment: EXISTENCE:mutant phenotype:GO:0000741 karyogamy [PMID:16923827]
experiment: EXISTENCE:mutant phenotype:GO:0000743 nuclear migration involved in conjugation with cellular fusion [PMID:12493774]
experiment: EXISTENCE:mutant phenotype:GO:0007064 mitotic sister chromatid cohesion [PMID:15355977]
experiment: EXISTENCE:mutant phenotype:GO:0007129 homologous chromosome pairing at meiosis [PMID:17495028]
experiment: EXISTENCE:mutant phenotype:GO:0030474 spindle pole body duplication [PMID:12486115|PMID:16923827]
experiment: EXISTENCE:mutant phenotype:GO:0031509 subtelomeric heterochromatin formation [PMID:22593213]
experiment: EXISTENCE:mutant phenotype:GO:0034087 establishment of mitotic sister chromatid cohesion [PMID:22593213]
experiment: EXISTENCE:mutant phenotype:GO:0034398 telomere tethering at nuclear periphery [PMID:18039933|PMID:22593213]
experiment: EXISTENCE:mutant phenotype:GO:0045141 meiotic telomere clustering [PMID:17495028]
note: Nuclear envelope protein; required for SPB insertion, SPB duplication, Kar5p localization near the SPB and nuclear fusion; interacts with Mps2p to tether half-bridge to core SPB; N-terminal acetylation by Eco1p regulates its role in nuclear organization; localizes to the SPB half bridge and telomeres during meiosis; required with Ndj1p and Csm4p for meiotic bouquet formation and telomere-led rapid prophase movement; member of the SUN protein family (Sad1-UNC-84 homology)
codon start: 1
product: Mps3p
translation: MNNSNEHRREEAGAANEQMPYNKAVKSAYADVLKDKMNREQEISLRAIKKGIYTDGGETDNYDMDKENDSAYEMFKKNLDFPLDQHNDDDDDDPYIEDNGQETDGYSDEDYTDEADKSFIEDSDSDSYDLESNSDFEENLESSGEAKKLKWRTYIFYGGLFFVFYFFGSFLMTTVKNNDLESHSSGATSSPGKSFSNLQKQVNHLYSELSKRDEKHSSELDKTVKIIVSQFEKNIKRLLPSNLVNFENDINSLTKQVETISTSMSELQRRNHKFTVENVTQWQDQLVKQLDTHLPQEIPVVINNSSSLLIIPELHNYLSALISDVIESPGIGTAGSAESRWEYDLNRYVKEILSNELQYIDKDYFIQEMNRRLQSNKQEIWEEITNRLETQQQQQQQQVQQDYSNVPQQYSSILMKRLIHQIYNSNQHQWEDDLDFATYVQGTKLLNHLTSPTWRQGSGVQPIELLTDSKQSSSTYWQCENEPGCSWAIRFKTPLYLTKISYMHGRFTNNLHIMNSAPRLISLYVKLSQTKEIKALQTLANQYGFGQHHKRDRNYIKIAKFEYRLTDSRIRQQMYLPPWFIQLKPLVRSIVFQVDENYGNKKFISLRKFIINGVTPQDLQIIENNEFPVLLGDTPEYGVTQNTDEGKRKVLLSKPPYASSSTSTKFHPASNVPSFGQDELDQ
SIO_010081: YJL019W
subclass of: SO_0000673
so part of: YJL019W
location: 402897..404945
location: region:402897-404945:1
so has part: feature:402897-404945:1:exon

NP_012515.4
type: Protein
SIO_000068: ncbiprotein

S000003556
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:402897-404945:1:exon

YJL016W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YJL017W
gene: TPH3
locus tag: YJL016W
gene synonym: YJL017W
so part of: sequence
location: <405588..>407273
location: region:405588-407273:1
so has part: feature:405588-407273:1:exon
subclass of: SO_0000010

853436
type: Gene
SIO_000068: ncbigene

position:405588:1
position: 405588
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:407273:1
position: 407273
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:405588-407273:1:exon

YJL016W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YJL017W
gene: TPH3
locus tag: YJL016W
gene synonym: YJL017W
product: Tph3p
transcript id: NM_001181450.1
SIO_010081: YJL016W
subclass of: SO_0000673
so part of: YJL016W
location: <405588..>407273
location: region:405588-407273:1
so has part: feature:405588-407273:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:405588-407273:1:exon

YJL016W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YJL017W
gene: TPH3
locus tag: YJL016W
gene synonym: YJL017W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
note: hypothetical protein; GFP-fusion protein localizes to the cytoplasm; contains two adjacent PH-like domains; conserved in closely related Saccharomyces species
codon start: 1
product: Tph3p
translation: MGILDSLKKPVNIKSSLPKFSRSATSINLSSHPVSSRSFLELPPELFSITKPIFKLLQAHANKIYFQSSDAEAVWNVKDSSGHVFEAESISLLGSHIIITNSSVQVADVAIIDSPSNINQCEISSVGEFLQFNNGQLSITCNDFGLLEKFKRLCMISIFEFISIYKALTGTVISSYGLRMSDMHIILNSPFNFKDWCEVYLDGQGWVKVWCHIDKVSKTNNSKSSSDNDAKGKYQIRFYRDDKSTSSKNCVFFIPDNEYVQDIFFYNINAAEPSKNMNDFFQGLQMIKLVGNVRFCSDTDFNDVVDSGSIYSSANNGSGDSSSTALNNESPNTTPKSRTFFSPKGHRRNSSHVSSLTSRSTKKPITNFTTRTNGLLIRPLPHHGVHHLEAMIRFIIPLMDCARLYGRPVQFKTERTDINSLMFGLPKLPSVDYFAEEEIAHLMTQEFNPLKEKDTDDTMALTMSRFSSYLQERMTKVSKRNTELNFRTFSDVMGMYNTTRDHSKLNCMSDKDNSVKEFSLSDKSNVSSETTNMMNQLQVNAHEYKSSMCERPIVASTSPIA
SIO_010081: YJL016W
subclass of: SO_0000673
so part of: YJL016W
location: 405588..407273
location: region:405588-407273:1
so has part: feature:405588-407273:1:exon

NP_012518.2
type: Protein
SIO_000068: ncbiprotein

S000003553
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:405588-407273:1:exon

YJL014W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: BIN2
alternative label: TCP3
gene: CCT3
locus tag: YJL014W
gene synonym: BIN2; TCP3
so part of: sequence
location: <407558..>409162
location: region:407558-409162:1
so has part: feature:407558-409162:1:exon
subclass of: SO_0000010

853438
type: Gene
SIO_000068: ncbigene

position:407558:1
position: 407558
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:409162:1
position: 409162
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:407558-409162:1:exon

YJL014W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: BIN2
alternative label: TCP3
gene: CCT3
locus tag: YJL014W
gene synonym: BIN2; TCP3
product: chaperonin-containing T-complex subunit CCT3
transcript id: NM_001181448.1
SIO_010081: YJL014W
subclass of: SO_0000673
so part of: YJL014W
location: <407558..>409162
location: region:407558-409162:1
so has part: feature:407558-409162:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:407558-409162:1:exon

YJL014W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: BIN2
alternative label: TCP3
gene: CCT3
locus tag: YJL014W
gene synonym: BIN2; TCP3
experiment: EXISTENCE:direct assay:GO:0005832 chaperonin-containing T-complex [PMID:16762366]
experiment: EXISTENCE:direct assay:GO:0006457 protein folding [PMID:16762366]
experiment: EXISTENCE:direct assay:GO:0051082 unfolded protein binding [PMID:16762366]
experiment: EXISTENCE:physical interaction:GO:0005832 chaperonin-containing T-complex [PMID:15704212]
note: Subunit of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo; capable of binding Q/N rich proteins and mediating their folding
codon start: 1
product: chaperonin-containing T-complex subunit CCT3
translation: MQAPVVFMNASQERTTGRQAQISNITAAKAVADVIRTCLGPKAMLKMLLDPMGGLVLTNDGHAILREIDVAHPAAKSMLELSRTQDEEVGDGTTTVIILAGEILAQCAPYLIEKNIHPVIIIQALKKALTDALEVIKQVSKPVDVENDAAMKKLIQASIGTKYVIHWSEKMCELALDAVKTVRKDLGQTVEGEPNFEIDIKRYVRVEKIPGGDVLDSRVLKGVLLNKDVVHPKMSRHIENPRVVLLDCPLEYKKGESQTNIEIEKEEDWNRILQIEEEQVQLMCEQILAVRPTLVITEKGVSDLAQHYLLKGGCSVLRRVKKSDNNRIARVTGATIVNRVEDLKESDVGTNCGLFKVEMIGDEYFSFLDNCKEPKACTIMLRGGSKDILNEIDRNLQDAMAVARNVMLSPSLSPGGGATEMAVSVKLAEKAKQLEGIQQWPYQAVADAMECIPRTLIQNAGGDPIRLLSQLRAKHAQGNFTTGIDGDKGKIVDMVSYGIWEPEVIKQQSVKTAIESACLLLRVDDIVSGVRKQE
SIO_010081: YJL014W
subclass of: SO_0000673
so part of: YJL014W
location: 407558..409162
location: region:407558-409162:1
so has part: feature:407558-409162:1:exon

NP_012520.1
type: Protein
SIO_000068: ncbiprotein

S000003551
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:407558-409162:1:exon

YJL013C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MAD3
locus tag: YJL013C
so part of: sequence
location: complement(<409493..>411040)
location: region:409493-411040:-1
so has part: feature:409493-411040:-1:exon
subclass of: SO_0000010

853439
type: Gene
SIO_000068: ncbigene

position:409493:-1
position: 409493
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:411040:-1
position: 411040
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:409493-411040:-1:exon

YJL013C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MAD3
locus tag: YJL013C
product: Mad3p
transcript id: NM_001181447.3
SIO_010081: YJL013C
subclass of: SO_0000673
so part of: YJL013C
location: complement(<409493..>411040)
location: region:409493-411040:-1
so has part: feature:409493-411040:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:409493-411040:-1:exon

YJL013C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MAD3
locus tag: YJL013C
experiment: EXISTENCE:direct assay:GO:0033597 mitotic checkpoint complex [PMID:11726501]
experiment: EXISTENCE:direct assay:GO:1902499 positive regulation of protein autoubiquitination [PMID:22940250]
experiment: EXISTENCE:genetic interaction:GO:0044774 mitotic DNA integrity checkpoint signaling [PMID:16651657]
experiment: EXISTENCE:mutant phenotype:GO:0007094 mitotic spindle assembly checkpoint signaling [PMID:10704439]
experiment: EXISTENCE:mutant phenotype:GO:0032837 distributive segregation [PMID:15951820]
experiment: EXISTENCE:mutant phenotype:GO:0033597 mitotic checkpoint complex [PMID:10704439]
experiment: EXISTENCE:physical interaction:GO:0033597 mitotic checkpoint complex [PMID:10704439|PMID:11726501]
note: Subunit of spindle-assembly checkpoint complex; involved in delaying anaphase onset in cells with defects in mitotic spindle assembly; pseudosubstrate inhibitor of APC(Cdc20), the anaphase promoting complex involved in securin (Pds1p) turnover; MAD3 has a paralog, BUB1, that arose from the whole genome duplication
codon start: 1
product: Mad3p
translation: MKAYAKKRISYMPSSPSQNVINFEEIETQKENILPLKEGRSAAALSKAIHQPLVEINQVKSSFEQRLIDELPALSDPITLYLEYIKWLNNAYPQGGNSKQSGMLTLLERCLSHLKDLERYRNDVRFLKIWFWYIELFTRNSFMESRDIFMYMLRNGIGSELASFYEEFTNLLIQKEKFQYAVKILQLGIKNKARPNKVLEDRLNHLLRELGENNIQLGNEISMDSLESTVLGKTRSEFVNRLELANQNGTSSDVNLTKNNVFVDGEESDVELFETPNRGVYRDGWENFDLKAERNKENNLRISLLEANTNLGELKQHEMLSQKKRPYDEKLPIFRDSIGRSDPVYQMINTKDQKPEKIDCNFKLIYCEDEESKGGRLEFSLEEVLAISRNVYKRVRTNRKHPREANLGQEESANQKEAEAQSKRPKISRKALVSKSLTPSNQGRMFSGEEYINCPMTPKGRSTETSDIISAVKPRQLTPILEMRESNSFSQSKNSEIISDDDKSSSSFISYPPQR
SIO_010081: YJL013C
subclass of: SO_0000673
so part of: YJL013C
location: complement(409493..411040)
location: region:409493-411040:-1
so has part: feature:409493-411040:-1:exon

NP_012521.3
type: Protein
SIO_000068: ncbiprotein

S000003550
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:409493-411040:-1:exon

YJL012C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PHM3
alternative label: YJL012C-A
gene: VTC4
locus tag: YJL012C
gene synonym: PHM3; YJL012C-A
so part of: sequence
location: complement(<411234..>413399)
location: region:411234-413399:-1
so has part: feature:411234-413399:-1:exon
subclass of: SO_0000010

853441
type: Gene
SIO_000068: ncbigene

position:411234:-1
position: 411234
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:413399:-1
position: 413399
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:411234-413399:-1:exon

YJL012C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PHM3
alternative label: YJL012C-A
gene: VTC4
locus tag: YJL012C
gene synonym: PHM3; YJL012C-A
product: Vtc4p
transcript id: NM_001181446.1
SIO_010081: YJL012C
subclass of: SO_0000673
so part of: YJL012C
location: complement(<411234..>413399)
location: region:411234-413399:-1
so has part: feature:411234-413399:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:411234-413399:-1:exon

YJL012C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PHM3
alternative label: YJL012C-A
gene: VTC4
locus tag: YJL012C
gene synonym: PHM3; YJL012C-A
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0000822 inositol hexakisphosphate binding [PMID:27080106]
experiment: EXISTENCE:direct assay:GO:0005516 calmodulin binding [PMID:17079729]
experiment: EXISTENCE:direct assay:GO:0005774 vacuolar membrane [PMID:12584253]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:17079729]
experiment: EXISTENCE:direct assay:GO:0007034 vacuolar transport [PMID:17079729]
experiment: EXISTENCE:direct assay:GO:0008976 polyphosphate kinase activity [PMID:19390046]
experiment: EXISTENCE:direct assay:GO:0016237 lysosomal microautophagy [PMID:17079729]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0006797 polyphosphate metabolic process [PMID:11102525|PMID:19390046]
experiment: EXISTENCE:mutant phenotype:GO:0006799 polyphosphate biosynthetic process [PMID:27252384|PMID:27080106]
experiment: EXISTENCE:mutant phenotype:GO:0007034 vacuolar transport [PMID:17079729]
experiment: EXISTENCE:mutant phenotype:GO:0016237 lysosomal microautophagy [PMID:17079729]
experiment: EXISTENCE:mutant phenotype:GO:0042144 vacuole fusion, non-autophagic [PMID:11823419|PMID:27252384]
experiment: EXISTENCE:mutant phenotype:GO:0048016 inositol phosphate-mediated signaling [PMID:27080106]
experiment: EXISTENCE:physical interaction:GO:0033254 vacuolar transporter chaperone complex [PMID:11823419]
note: Vacuolar membrane polyphosphate polymerase; subunit of vacuolar transporter chaperone (VTC) complex involved in synthesis and transfer of polyP to vacuole; regulates membrane trafficking; role in non-autophagic vacuolar fusion; targeted to vacuole via AP-3 pathway; protein abundance increases in response to DNA replication stress
codon start: 1
product: Vtc4p
translation: MKFGEHLSKSLIRQYSYYYISYDDLKTELEDNLSKNNGQWTQELETDFLESLEIELDKVYTFCKVKHSEVFRRVKEVQEQVQHTVRLLDSNNPPTQLDFEILEEELSDIIADVHDLAKFSRLNYTGFQKIIKKHDKKTGFILKPVFQVRLDSKPFFKENYDELVVKISQLYDIARTSGRPIKGDSSAGGKQQNFVRQTTKYWVHPDNITELKLIILKHLPVLVFNTNKEFEREDSAITSIYFDNENLDLYYGRLRKDEGAEAHRLRWYGGMSTDTIFVERKTHREDWTGEKSVKARFALKERHVNDFLKGKYTVDQVFAKMRKEGKKPMNEIENLEALASEIQYVMLKKKLRPVVRSFYNRTAFQLPGDARVRISLDTELTMVREDNFDGVDRTHKNWRRTDIGVDWPFKQLDDKDICRFPYAVLEVKLQTQLGQEPPEWVRELVGSHLVEPVPKFSKFIHGVATLLNDKVDSIPFWLPQMDVDIRKPPLPTNIEITRPGRSDNEDNDFDEDDEDDAALVAAMTNAPGNSLDIEESVGYGATSAPTSNTNHVVESANAAYYQRKIRNAENPISKKYYEIVAFFDHYFNGDQISKIPKGTTFDTQIRAPPGKTICVPVRVEPKVYFATERTYLSWLSISILLGGVSTTLLTYGSPTAMIGSIGFFITSLAVLIRTVMVYAKRVVNIRLKRAVDYEDKIGPGMVSVFLILSILFSFFCNLVAK
SIO_010081: YJL012C
subclass of: SO_0000673
so part of: YJL012C
location: complement(411234..413399)
location: region:411234-413399:-1
so has part: feature:411234-413399:-1:exon

NP_012522.2
type: Protein
SIO_000068: ncbiprotein

S000003549
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:411234-413399:-1:exon

YJL011C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RPC17
locus tag: YJL011C
so part of: sequence
location: complement(<414285..>414770)
location: region:414285-414770:-1
so has part: feature:414285-414770:-1:exon
subclass of: SO_0000010

853442
type: Gene
SIO_000068: ncbigene

position:414285:-1
position: 414285
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:414770:-1
position: 414770
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:414285-414770:-1:exon

YJL011C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RPC17
locus tag: YJL011C
product: DNA-directed RNA polymerase III subunit RPC17
transcript id: NM_001181445.2
SIO_010081: YJL011C
subclass of: SO_0000673
so part of: YJL011C
location: complement(<414285..>414770)
location: region:414285-414770:-1
so has part: feature:414285-414770:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:414285-414770:-1:exon

YJL011C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RPC17
locus tag: YJL011C
experiment: EXISTENCE:direct assay:GO:0001056 RNA polymerase III activity [PMID:10611227|PMID:3905793]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0005666 RNA polymerase III complex [PMID:10611227|PMID:3905793]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0042797 tRNA transcription by RNA polymerase III [PMID:3905793]
experiment: EXISTENCE:mutant phenotype:GO:0042797 tRNA transcription by RNA polymerase III [PMID:10611227]
experiment: EXISTENCE:physical interaction:GO:0006384 transcription initiation at RNA polymerase III promoter [PMID:10611227]
note: RNA polymerase III subunit C17; physically interacts with C31, C11, and TFIIIB70; may be involved in the recruitment of pol III by the preinitiation complex; protein abundance increases in response to DNA replication stress; relocalizes to the cytosol in response to hypoxia
codon start: 1
product: DNA-directed RNA polymerase III subunit RPC17
translation: MKVLEERNAFLSDYEVLKFLTDLEKKHLWDQKSLAALKKSRSKGKQNRPYNHPELQGITRNVVNYLSINKNFINQEDEGEERESSGAKDAEKSGISKMSDESFAELMTKLNSFKLFKAEKLQIVNQLPANMVHLYSIVEECDARFDEKTIEEMLEIISGYA
SIO_010081: YJL011C
subclass of: SO_0000673
so part of: YJL011C
location: complement(414285..414770)
location: region:414285-414770:-1
so has part: feature:414285-414770:-1:exon

NP_012523.2
type: Protein
SIO_000068: ncbiprotein

S000003548
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:414285-414770:-1:exon

YNCJ0018W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCJ0018W
so part of: sequence
location: 414966..415038
location: region:414966-415038:1
so has part: feature:414966-415038:1:exon
subclass of: SO_0000663

853443
type: Gene
SIO_000068: ncbigene

position:414966:1
position: 414966
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:415038:1
position: 415038
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:414966-415038:1:exon

YNCJ0018W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCJ0018W
product: tRNA-Lys
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:8915539]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:8915539]
experiment: EXISTENCE:mutant phenotype:GO:0030533 triplet codon-amino acid adaptor activity [PMID:17560369]
experiment: EXISTENCE:mutant phenotype:GO:0032543 mitochondrial translation [PMID:17560369]
note: Lysine tRNA (tRNA-Lys), predicted by tRNAscan-SE analysis; a small portion is imported into mitochondria via interaction with mt lysyl-tRNA synthetase Msk1p and is necessary to decode AAG codons at high temperature, when base modification of mt-encoded tRNA-Lys is reduced
SIO_010081: YNCJ0018W
subclass of: SO_0000673
so part of: YNCJ0018W
location: 414966..415038
location: region:414966-415038:1
so has part: feature:414966-415038:1:exon

S000006625
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:414966-415038:1:exon

YNCJ0019C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCJ0019C
so part of: sequence
location: complement(415931..416036)
location: region:415931-416036:-1
so has part: feature:415931-416036:-1:exon
subclass of: SO_0000663

853444
type: Gene
SIO_000068: ncbigene

position:415931:-1
position: 415931
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:416036:-1
position: 416036
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:415931-416036:-1:exon

YNCJ0019C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCJ0019C
product: tRNA-Trp
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Tryptophan tRNA (tRNA-Trp), predicted by tRNAscan-SE analysis
SIO_010081: YNCJ0019C
subclass of: SO_0000673
so part of: YNCJ0019C
location: complement(join(415931..415966,416001..416036))
location: region:415931-416036:-1
so has part: feature:416001-416036:-1:exon
so has part: feature:415931-415966:-1:exon

S000006773
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:416001-416036:-1:exon

position:416001:-1
position: 416001
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:415931-415966:-1:exon

position:415966:-1
position: 415966
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty4 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 416266..416441
location: region:416266-416441:1
so has part: feature:416266-416441:1:region

S000007047
type: SGD
SIO_000068: sgd

position:416266:1
position: 416266
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:416441:1
position: 416441
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:416266-416441:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 416506..416650
location: region:416506-416650:1
so has part: feature:416506-416650:1:region

S000007029
type: SGD
SIO_000068: sgd

position:416506:1
position: 416506
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:416650:1
position: 416650
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:416506-416650:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 416899..417026
location: region:416899-417026:1
so has part: feature:416899-417026:1:region

S000007030
type: SGD
SIO_000068: sgd

position:416899:1
position: 416899
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:417026:1
position: 417026
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:416899-417026:1:region

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1014; Autonomously Replicating Sequence
so part of: sequence
location: 417195..417440
location: region:417195-417440:1
so has part: feature:417195-417440:1:region

S000028451
type: SGD
SIO_000068: sgd

position:417195:1
position: 417195
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:417440:1
position: 417440
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:417195-417440:1:region

YJL010C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: NOP9
locus tag: YJL010C
so part of: sequence
location: complement(<417562..>419562)
location: region:417562-419562:-1
so has part: feature:417562-419562:-1:exon
subclass of: SO_0000010

853445
type: Gene
SIO_000068: ncbigene

position:417562:-1
position: 417562
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:419562:-1
position: 419562
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:417562-419562:-1:exon

YJL010C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: NOP9
locus tag: YJL010C
product: RNA-binding RNA processing protein NOP9
transcript id: NM_001181444.3
SIO_010081: YJL010C
subclass of: SO_0000673
so part of: YJL010C
location: complement(<417562..>419562)
location: region:417562-419562:-1
so has part: feature:417562-419562:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:417562-419562:-1:exon

YJL010C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: NOP9
locus tag: YJL010C
experiment: EXISTENCE:direct assay:GO:0003723 RNA binding [PMID:17956976]
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095|PMID:14690591]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:17956976|PMID:14562095|PMID:14690591]
experiment: EXISTENCE:direct assay:GO:0030686 90S preribosome [PMID:17956976]
experiment: EXISTENCE:direct assay:GO:0030688 preribosome, small subunit precursor [PMID:17956976]
experiment: EXISTENCE:mutant phenotype:GO:0000056 ribosomal small subunit export from nucleus [PMID:17956976]
experiment: EXISTENCE:mutant phenotype:GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:17956976]
experiment: EXISTENCE:mutant phenotype:GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:17956976]
experiment: EXISTENCE:mutant phenotype:GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:17956976]
note: Essential subunit of U3-containing 90S preribosome; involved in production of 18S rRNA and assembly of small ribosomal subunit; also part of pre-40S ribosome and required for its export into cytoplasm; binds RNA and contains pumilio domain
codon start: 1
product: RNA-binding RNA processing protein NOP9
translation: MGKTKTRGRRHQDKQRKDEFEPSSNSAKEHIQQEESTYNDEAEIKETQPQMFFGVLDREELEYFKQAESTLQLDAFEAPEEKFQFVTSIIEEAKGKELKLVTSQITSKLMERVILECDETQLKDIFQSFNGVFFGLSCHKYASHVLETLFVRSAALVERELLTPSFDNNEKEGPYVTMENMFLFMLNELKPHLKTMMNHQYASHVLRLLILILSSKTLPNSTKANSTLRSKKSKIARKMIDIKDNDDFNKVYQTPESFKSELRDIITTLYKGFTNGAESRSDISQSTITKFREYSVDKVASPVIQLIIQVEGIFDRDRSFWRLVFNTADEKDPKEESFLEYLLSDPVGSHFLENVIGSARLKYVERLYRLYMKDRIVKLAKRDTTGAFVVRALLEHLKEKDVKQILDAVVPELSMLLNSNMDFGTAIINASNKQGGYLRDDVIAQLIQKYYPEKSDAKNILESCLLLSASTLGNTRDDWPTAEERRRSVFLEQLIDYDDKFLNITIDSMLALPEERLIQMCYHGVFSHVVEHVLQTTRVDIIKRKMLLNILSKESVNLACNVYGSHIMDKLWEFTAKLTLYKERIARALVLETEKVKNSIYGRQVWKNWKLELYVRKMWDWKKLIKEQEFEIFPNSKPLQPKPEKHSRERNNSKEGSAFKKQKHYR
SIO_010081: YJL010C
subclass of: SO_0000673
so part of: YJL010C
location: complement(417562..419562)
location: region:417562-419562:-1
so has part: feature:417562-419562:-1:exon

NP_012524.3
type: Protein
SIO_000068: ncbiprotein

S000003547
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:417562-419562:-1:exon

YJL008C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CCT8
locus tag: YJL008C
so part of: sequence
location: complement(<419957..>421663)
location: region:419957-421663:-1
so has part: feature:419957-421663:-1:exon
subclass of: SO_0000010

853447
type: Gene
SIO_000068: ncbigene

position:419957:-1
position: 419957
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:421663:-1
position: 421663
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:419957-421663:-1:exon

YJL008C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CCT8
locus tag: YJL008C
product: chaperonin-containing T-complex subunit CCT8
transcript id: NM_001181442.2
SIO_010081: YJL008C
subclass of: SO_0000673
so part of: YJL008C
location: complement(<419957..>421663)
location: region:419957-421663:-1
so has part: feature:419957-421663:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:419957-421663:-1:exon

YJL008C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CCT8
locus tag: YJL008C
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005832 chaperonin-containing T-complex [PMID:16762366]
experiment: EXISTENCE:direct assay:GO:0006457 protein folding [PMID:16762366]
experiment: EXISTENCE:direct assay:GO:0051082 unfolded protein binding [PMID:16762366]
experiment: EXISTENCE:physical interaction:GO:0005832 chaperonin-containing T-complex [PMID:15704212]
note: Subunit of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo
codon start: 1
product: chaperonin-containing T-complex subunit CCT8
translation: MSLRLPQNPNAGLFKQGYNSYSNADGQIIKSIAAIRELHQMCLTSMGPCGRNKIIVNHLGKIIITNDAATMLRELDIVHPAVKVLVMATEQQKIDMGDGTNLVMILAGELLNVSEKLISMGLSAVEIIQGYNMARKFTLKELDEMVVGEITDKNDKNELLKMIKPVISSKKYGSEDILSELVSEAVSHVLPVAQQAGEIPYFNVDSIRVVKIMGGSLSNSTVIKGMVFNREPEGHVKSLSEDKKHKVAVFTCPLDIANTETKGTVLLHNAQEMLDFSKGEEKQIDAMMKEIADMGVECIVAGAGVGELALHYLNRYGILVLKVPSKFELRRLCRVCGATPLPRLGAPTPEELGLVETVKTMEIGGDRVTVFKQEQGEISRTSTIILRGATQNNLDDIERAIDDGVAAVKGLMKPSGGKLLPGAGATEIELISRITKYGERTPGLLQLAIKQFAVAFEVVPRTLAETAGLDVNEVLPNLYAAHNVTEPGAVKTDHLYKGVDIDGESDEGVKDIREENIYDMLATKKFAINVATEAATTVLSIDQIIMAKKAGGPRAPQGPRPGNWDQED
SIO_010081: YJL008C
subclass of: SO_0000673
so part of: YJL008C
location: complement(419957..421663)
location: region:419957-421663:-1
so has part: feature:419957-421663:-1:exon

NP_012526.1
type: Protein
SIO_000068: ncbiprotein

S000003545
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:419957-421663:-1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty4 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 421946..422295
location: region:421946-422295:1
so has part: feature:421946-422295:1:region

S000007038
type: SGD
SIO_000068: sgd

position:421946:1
position: 421946
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:422295:1
position: 422295
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:421946-422295:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 422601..422887
location: region:422601-422887:1
so has part: feature:422601-422887:1:region

S000007031
type: SGD
SIO_000068: sgd

position:422601:1
position: 422601
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:422887:1
position: 422887
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:422601-422887:1:region

YJL007C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJL007C
so part of: sequence
location: complement(<422698..>423012)
location: region:422698-423012:-1
so has part: feature:422698-423012:-1:exon
subclass of: SO_0000010

853449
type: Gene
SIO_000068: ncbigene

position:422698:-1
position: 422698
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:423012:-1
position: 423012
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:422698-423012:-1:exon

YJL007C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJL007C
product: uncharacterized protein
transcript id: NM_001348847.1
SIO_010081: YJL007C
subclass of: SO_0000673
so part of: YJL007C
location: complement(<422698..>423012)
location: region:422698-423012:-1
so has part: feature:422698-423012:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:422698-423012:-1:exon

YJL007C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJL007C
note: hypothetical protein; conserved among S. cerevisiae strains
codon start: 1
product: uncharacterized protein
translation: MCSRGGSNSRPSDYETDALPTELLKHTKDVGEEKQTLHQIFADSMVIKGYSTGYTGHTRSSPGDLVIHKRELIFSHNIVIIVSPIYMISFIILLHYQSWHFSIY
SIO_010081: YJL007C
subclass of: SO_0000673
so part of: YJL007C
location: complement(422698..423012)
location: region:422698-423012:-1
so has part: feature:422698-423012:-1:exon

NP_001335787.1
type: Protein
SIO_000068: ncbiprotein

S000003544
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:422698-423012:-1:exon

YNCJ0020W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: EMT3
locus tag: YNCJ0020W
so part of: sequence
location: 422937..423009
location: region:422937-423009:1
so has part: feature:422937-423009:1:exon
subclass of: SO_0000663

853448
type: Gene
SIO_000068: ncbigene

position:422937:1
position: 422937
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:423009:1
position: 423009
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:422937-423009:1:exon

YNCJ0020W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
gene: EMT3
locus tag: YNCJ0020W
product: tRNA-Met
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Methionine tRNA (tRNA-Met), functions in translational elongation; not involved in translational initiation; predicted by tRNAscan-SE analysis
SIO_010081: YNCJ0020W
subclass of: SO_0000673
so part of: YNCJ0020W
location: 422937..423009
location: region:422937-423009:1
so has part: feature:422937-423009:1:exon

S000006662
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:422937-423009:1:exon

YJL006C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CTK2
locus tag: YJL006C
so part of: sequence
location: complement(<423138..>424109)
location: region:423138-424109:-1
so has part: feature:423138-424109:-1:exon
subclass of: SO_0000010

853450
type: Gene
SIO_000068: ncbigene

position:423138:-1
position: 423138
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:424109:-1
position: 424109
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:423138-424109:-1:exon

YJL006C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CTK2
locus tag: YJL006C
product: Ctk2p
transcript id: NM_001181440.1
SIO_010081: YJL006C
subclass of: SO_0000673
so part of: YJL006C
location: complement(<423138..>424109)
location: region:423138-424109:-1
so has part: feature:423138-424109:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:423138-424109:-1:exon

YJL006C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CTK2
locus tag: YJL006C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0005654 nucleoplasm [PMID:15520468]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:15520468]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity [PMID:11118453]
experiment: EXISTENCE:direct assay:GO:0032786 positive regulation of DNA-templated transcription, elongation [PMID:9110987]
experiment: EXISTENCE:direct assay:GO:0070692 CTDK-1 complex [PMID:7565723]
experiment: EXISTENCE:direct assay:GO:0070816 phosphorylation of RNA polymerase II C-terminal domain [PMID:11118453]
experiment: EXISTENCE:mutant phenotype:GO:0045943 positive regulation of transcription by RNA polymerase I [PMID:15520468]
experiment: EXISTENCE:physical interaction:GO:0045903 positive regulation of translational fidelity [PMID:17545469]
note: Beta subunit of C-terminal domain kinase I (CTDK-I); which phosphorylates both RNA pol II subunit Rpo21p to affect transcription and pre-mRNA 3' end processing, and ribosomal protein Rps2p to increase translational fidelity; relocalizes to the cytosol in response to hypoxia
codon start: 1
product: Ctk2p
translation: MPSTFESQLFFSRPFLSKRQIQRAQKNTISDYRNYNQKKLAVFKFLSDLCVQLKFPRKTLETAVYFYQRYHLFNRFETEVCYTVATSCLTLGCKEVETIKKTNDICTLSLRLRNVVKINTDILENFKKRVFQIELRILESCSFDYRVNNYVHIDEYVIKIGRELSFDYKLCNLAWVIAYDALKLETILVIPQHSIALAILKIAYELLDNKNWSSKRYSLFETDEKSVNEAYFDIVNFYINSFDMCDLQRHLPADLLPIGVERFMELKKNAGPESGLPQIPDHLLNADPYITITRDNNVQERRYVLSLELINGESSINSSTRHA
SIO_010081: YJL006C
subclass of: SO_0000673
so part of: YJL006C
location: complement(423138..424109)
location: region:423138-424109:-1
so has part: feature:423138-424109:-1:exon

NP_012528.1
type: Protein
SIO_000068: ncbiprotein

S000003543
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:423138-424109:-1:exon

YNCJ0021C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SUP51
locus tag: YNCJ0021C
so part of: sequence
location: complement(424432..424515)
location: region:424432-424515:-1
so has part: feature:424432-424515:-1:exon
subclass of: SO_0000663

853451
type: Gene
SIO_000068: ncbigene

position:424432:-1
position: 424432
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:424515:-1
position: 424515
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:424432-424515:-1:exon

YNCJ0021C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
gene: SUP51
locus tag: YNCJ0021C
product: tRNA-Leu
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
experiment: EXISTENCE:direct assay:GO:0030371 translation repressor activity [PMID:27609601]
experiment: EXISTENCE:direct assay:GO:0043022 ribosome binding [PMID:27609601]
experiment: EXISTENCE:direct assay:GO:0043555 regulation of translation in response to stress [PMID:27609601]
note: Leucine tRNA (tRNA-Leu), predicted by tRNAscan-SE analysis; can mutate to suppress amber nonsense mutations
SIO_010081: YNCJ0021C
subclass of: SO_0000673
so part of: YNCJ0021C
location: complement(424432..424515)
location: region:424432-424515:-1
so has part: feature:424432-424515:-1:exon

S000006650
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:424432-424515:-1:exon

YJL005W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CDC35
alternative label: FIL1
alternative label: HSR1
alternative label: SRA4
alternative label: TSM0185
gene: CYR1
locus tag: YJL005W
gene synonym: CDC35; FIL1; HSR1; SRA4; TSM0185
so part of: sequence
location: <425157..>431237
location: region:425157-431237:1
so has part: feature:425157-431237:1:exon
subclass of: SO_0000010

853452
type: Gene
SIO_000068: ncbigene

position:425157:1
position: 425157
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:431237:1
position: 431237
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:425157-431237:1:exon

YJL005W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CDC35
alternative label: FIL1
alternative label: HSR1
alternative label: SRA4
alternative label: TSM0185
gene: CYR1
locus tag: YJL005W
gene synonym: CDC35; FIL1; HSR1; SRA4; TSM0185
product: adenylate cyclase
transcript id: NM_001181439.3
SIO_010081: YJL005W
subclass of: SO_0000673
so part of: YJL005W
location: <425157..>431237
location: region:425157-431237:1
so has part: feature:425157-431237:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:425157-431237:1:exon

YJL005W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CDC35
alternative label: FIL1
alternative label: HSR1
alternative label: SRA4
alternative label: TSM0185
gene: CYR1
locus tag: YJL005W
gene synonym: CDC35; FIL1; HSR1; SRA4; TSM0185
EC number: 4.6.1.1
experiment: EXISTENCE:direct assay:GO:0004016 adenylate cyclase activity [PMID:2934138]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:22575457|PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:22575457]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:2196438]
experiment: EXISTENCE:genetic interaction:GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway [PMID:2934138]
experiment: EXISTENCE:genetic interaction:GO:0007265 Ras protein signal transduction [PMID:2934138]
experiment: EXISTENCE:mutant phenotype:GO:0004016 adenylate cyclase activity [PMID:6360999]
note: Adenylate cyclase; required for cAMP production and cAMP-dependent protein kinase signaling; scaffold protein for Ras2-Ira interaction; the cAMP pathway controls a variety of cellular processes, including metabolism, cell cycle, stress response, stationary phase, and sporulation
codon start: 1
product: adenylate cyclase
translation: MSSKPDTGSEISGPQRQEEQEQQIEQSSPTEANDRSIHDEVPKVKKRHEQNSGHKSRRNSAYSYYSPRSLSMTKSRESITPNGMDDVSISNVEHPRPTEPKIKRGPYLLKKTLSSLSMTSANSTHDDNKDHGYALNSSKTHNYTSTHNHHDGHHDHHHVQFFPNRKPSLAETLFKRFSGSNSHDGNKSGKESKVANLSLSTVNPAPANRKPSKDSTLSNHLADNVPSTLRRKVSSLVRGSSVHDINNGIADKQIRPKAVAQSENTLHSSDVPNSKRSHRKSFLLGSTSSSSSRRGSNVSSMTNSDSASMATSGSHVLQHNVSNVSPTTKSKDSVNSESADHTNNKSEKVTPEYNENIPENSNSDNKREATTPTIETPISCKPSLFRLDTNLEDVTDITKTVPPTAVNSTLNSTHGTETASPKTVIMPEGPRKSVSMADLSVAAAAPNGEFTSTSNDRSQWVAPQSWDVETKRKKTKPKGRSKSRRSSIDADELDPMSPGPPSKKDSRHHHDRKDNESMVTAGDSNSSFVDICKENVPNDSKTALDTKSVNRLKSNLAMSPPSIRYAPSNLDGDYDTSSTSSSLPSSSISSEDTSSCSDSSSYTNAYMEANREQDNKTPILNKTKSYTKKFTSSSVNMNSPDGAQSSGLLLQDEKDDEVECQLEHYYKDFSDLDPKRHYAIRIFNTDDTFTTLSCTPATTVEEIIPALKRKFNITAQGNFQISLKVGKLSKILRPTSKPILIERKLLLLNGYRKSDPLHIMGIEDLSFVFKFLFHPVTPSHFTPEQEQRIMRSEFVHVDLRNMDLTTPPIIFYQHTSEIESLDVSNNANIFLPLEFIESSIKLLSLRMVNIRASKFPSNITKAYKLVSLELQRNFIRKVPNSIMKLSNLTILNLQCNELESLPAGFVELKNLQLLDLSSNKFMHYPEVINYCTNLLQIDLSYNKIQSLPQSTKYLVKLAKMNLSHNKLNFIGDLSEMTDLRTLNLRYNRISSIKTNASNLQNLFLTDNRISNFEDTLPKLRALEIQENPITSISFKDFYPKNMTSLTLNKAQLSSIPGELLTKLSFLEKLELNQNNLTRLPQEISKLTKLVFLSVARNKLEYIPPELSQLKSLRTLDLHSNNIRDFVDGMENLELTSLNISSNAFGNSSLENSFYHNMSYGSKLSKSLMFFIAADNQFDDAMWPLFNCFVNLKVLNLSYNNFSDVSHMKLESITELYLSGNKLTTLSGDTVLKWSSLKTLMLNSNQMLSLPAELSNLSQLSVFDVGANQLKYNISNYHYDWNWRNNKELKYLNFSGNRRFEIKSFISHDIDADLSDLTVLPQLKVLGLMDVTLNTTKVPDENVNFRLRTTASIINGMRYGVADTLGQRDYVSSRDVTFERFRGNDDECLLCLHDSKNQNADYGHNISRIVRDIYDKILIRQLERYGDETDDNIKTALRFSFLQLNKEINGMLNSVDNGADVANLSYADLLSGACSTVIYIRGKKLFAANLGDCMAILSKNNGDYQTLTKQHLPTKREEYERIRISGGYVNNGKLDGVVDVSRAVGFFDLLPHIHASPDISVVTLTKADEMLIVATHKLWEYMDVDTVCDIARENSTDPLRAAAELKDHAMAYGCTENITILCLALYENIQQQNRFTLNKNSLMTRRSTFEDTTLRRLQPEISPPTGNLAMVFTDIKSSTFLWELFPNAMRTAIKTHNDIMRRQLRIYGGYEVKTEGDAFMVAFPTPTSGLTWCLSVQLKLLDAQWPEEITSVQDGCQVTDRNGNIIYQGLSVRMGIHWGCPVPELDLVTQRMDYLGPMVNKAARVQGVADGGQIAMSSDFYSEFNKIMKYHERVVKGKESLKEVYGEEIIGEVLEREIAMLESIGWAFFDFGEHKLKGLETKELVTIAYPKILASRHEFASEDEQSKLINETMLFRLRVISNRLESIMSALSGGFIELDSRTEGSYIKFNPKVENGIMQSISEKDALLFFDHVITRIESSVALLHLRQQRCSGLEICRNDK…
SIO_010081: YJL005W
subclass of: SO_0000673
so part of: YJL005W
location: 425157..431237
location: region:425157-431237:1
so has part: feature:425157-431237:1:exon

NP_012529.3
type: Protein
SIO_000068: ncbiprotein

S000003542
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:425157-431237:1:exon

YJL004C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SYS1
locus tag: YJL004C
so part of: sequence
location: complement(<431589..>432200)
location: region:431589-432200:-1
so has part: feature:431589-432200:-1:exon
subclass of: SO_0000010

853453
type: Gene
SIO_000068: ncbigene

position:431589:-1
position: 431589
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:432200:-1
position: 432200
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:431589-432200:-1:exon

YJL004C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SYS1
locus tag: YJL004C
product: Sys1p
transcript id: NM_001181438.1
SIO_010081: YJL004C
subclass of: SO_0000673
so part of: YJL004C
location: complement(<431589..>432200)
location: region:431589-432200:-1
so has part: feature:431589-432200:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:431589-432200:-1:exon

YJL004C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SYS1
locus tag: YJL004C
experiment: EXISTENCE:direct assay:GO:0000139 Golgi membrane [PMID:11726510]
experiment: EXISTENCE:direct assay:GO:0005802 trans-Golgi network [PMID:15077113]
experiment: EXISTENCE:genetic interaction:GO:0006895 Golgi to endosome transport [PMID:8923208]
experiment: EXISTENCE:mutant phenotype:GO:0034067 protein localization to Golgi apparatus [PMID:15077113|PMID:15077114]
experiment: EXISTENCE:mutant phenotype:GO:0043001 Golgi to plasma membrane protein transport [PMID:16926193]
note: Integral membrane protein of the Golgi; required for targeting of the Arf-like GTPase Arl3p to the Golgi; multicopy suppressor of ypt6 null mutation
codon start: 1
product: Sys1p
translation: MVSIRRYLRVPNELKPSQIFKQDSLSPSKIGLQIVLLQIFYYTTAIVLFYCWAKLAGYDLNIKEWLFSWENIDFTNAYGLSISLLWLLDSLICVFFLTVIVGRSKLAWDFAITIHAINFIVVFLYTRKFPSFSWFFLQILSSLILIFLGTWTTRWRELRDTFFEGLVDPNEGEVGLVTPSQQHSNHSELEQSPIQLKDLESQI
SIO_010081: YJL004C
subclass of: SO_0000673
so part of: YJL004C
location: complement(431589..432200)
location: region:431589-432200:-1
so has part: feature:431589-432200:-1:exon

NP_012530.1
type: Protein
SIO_000068: ncbiprotein

S000003541
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:431589-432200:-1:exon

YJL003W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: COX16
locus tag: YJL003W
so part of: sequence
location: <432644..>433000
location: region:432644-433000:1
so has part: feature:432644-433000:1:exon
subclass of: SO_0000010

853454
type: Gene
SIO_000068: ncbigene

position:432644:1
position: 432644
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:433000:1
position: 433000
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:432644-433000:1:exon

YJL003W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: COX16
locus tag: YJL003W
product: Cox16p
transcript id: NM_001181437.1
SIO_010081: YJL003W
subclass of: SO_0000673
so part of: YJL003W
location: <432644..>433000
location: region:432644-433000:1
so has part: feature:432644-433000:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:432644-433000:1:exon

YJL003W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: COX16
locus tag: YJL003W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005743 mitochondrial inner membrane [PMID:12446688]
experiment: EXISTENCE:mutant phenotype:GO:0033617 mitochondrial cytochrome c oxidase assembly [PMID:12446688]
note: Mitochondrial inner membrane protein; required for assembly of cytochrome c oxidase
codon start: 1
product: Cox16p
translation: MSFSGKKFRSRRQQLVYEASLAGRYKKALSKHPFLFFGLPFCATIVLGSFWLSSFTAIKYEQGDRKVQEINEEDILKIRKNQREFDIKEEYYRLQGLSEEDWEPVRVARLKDESENVW
SIO_010081: YJL003W
subclass of: SO_0000673
so part of: YJL003W
location: 432644..433000
location: region:432644-433000:1
so has part: feature:432644-433000:1:exon

NP_012531.1
type: Protein
SIO_000068: ncbiprotein

S000003540
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:432644-433000:1:exon

YJL002C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: NLT1
gene: OST1
locus tag: YJL002C
gene synonym: NLT1
so part of: sequence
location: complement(<433221..>434651)
location: region:433221-434651:-1
so has part: feature:433221-434651:-1:exon
subclass of: SO_0000010

853455
type: Gene
SIO_000068: ncbigene

position:433221:-1
position: 433221
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:434651:-1
position: 434651
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:433221-434651:-1:exon

YJL002C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: NLT1
gene: OST1
locus tag: YJL002C
gene synonym: NLT1
product: dolichyl-diphosphooligosaccharide--protein glycotransferase subunit OST1
transcript id: NM_001181436.3
SIO_010081: YJL002C
subclass of: SO_0000673
so part of: YJL002C
location: complement(<433221..>434651)
location: region:433221-434651:-1
so has part: feature:433221-434651:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:433221-434651:-1:exon

YJL002C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: NLT1
gene: OST1
locus tag: YJL002C
gene synonym: NLT1
experiment: EXISTENCE:direct assay:GO:0005198 structural molecule activity [PMID:29301962]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0006487 protein N-linked glycosylation [PMID:9015380]
experiment: EXISTENCE:direct assay:GO:0006488 dolichol-linked oligosaccharide biosynthetic process [PMID:29301962]
experiment: EXISTENCE:direct assay:GO:0008250 oligosaccharyltransferase complex [PMID:10358084]
experiment: EXISTENCE:direct assay:GO:0018279 protein N-linked glycosylation via asparagine [PMID:9988747]
experiment: EXISTENCE:physical interaction:GO:0008250 oligosaccharyltransferase complex [PMID:9405463]
note: Alpha subunit of the oligosaccharyltransferase complex of the ER lumen; complex catalyzes asparagine-linked glycosylation of newly synthesized proteins
codon start: 1
product: dolichyl-diphosphooligosaccharide--protein glycotransferase subunit OST1
translation: MRQVWFSWIVGLFLCFFNVSSAAQYEPPATWENVDYKRTIDVSNAYISETIEITIKNIASEPATEYFTAFESGIFSKVSFFSAYFTNEATFLNSQLLANSTTAPGDDGESEIRYGIIQFPNAISPQEEVSLVIKSFYNTVGIPYPEHVGMSEEQHLLWETNRLPLSAYDTKKASFTLIGSSSFEEYHPPNDESLLGKANGNSFEFGPWEDIPRFSSNETLAIVYSHNAPLNQVVNLRRDIWLSHWASTIQFEEYYELTNKAAKLSKGFSRLELMKQIQTQNMRQTHFVTVLDMLLPEGATDHYFTDLVGLVSTSHAERDHFFIRPRFPIFGGWNYNFTVGWTNKLSDFLHVSSGSDEKFVASIPILNGPPDTVYDNVELSVFLPEGAEIFDIDSPVPFTNVSIETQKSYFDLNKGHVKLTFSYRNLISQVANGQVLIKYDYPKSSFFKKPLSIACYIFTALMGVFVLKTLNMNVTN
SIO_010081: YJL002C
subclass of: SO_0000673
so part of: YJL002C
location: complement(433221..434651)
location: region:433221-434651:-1
so has part: feature:433221-434651:-1:exon

NP_012532.3
type: Protein
SIO_000068: ncbiprotein

S000003539
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:433221-434651:-1:exon

YJL001W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CRL21
gene: PRE3
locus tag: YJL001W
gene synonym: CRL21
so part of: sequence
location: <435163..>435926
location: region:435163-435926:1
so has part: feature:435163-435926:1:exon
subclass of: SO_0000010

853456
type: Gene
SIO_000068: ncbigene

position:435163:1
position: 435163
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:435926:1
position: 435926
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:435163-435926:1:exon

YJL001W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CRL21
gene: PRE3
locus tag: YJL001W
gene synonym: CRL21
product: proteasome core particle subunit beta 1
transcript id: NM_001181435.1
SIO_010081: YJL001W
subclass of: SO_0000673
so part of: YJL001W
location: join(<435163..435227,435344..>435926)
location: region:435163-435926:1
so has part: feature:435163-435227:1:exon
so has part: feature:435344-435926:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:435163-435227:1:exon

position:435227:1
position: 435227
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:435344-435926:1:exon

position:435344:1
position: 435344
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YJL001W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CRL21
gene: PRE3
locus tag: YJL001W
gene synonym: CRL21
EC number: 3.4.25.1
experiment: EXISTENCE:curator inference:GO:0005634 nucleus [PMID:9087403]
experiment: EXISTENCE:curator inference:GO:0005789 endoplasmic reticulum membrane [PMID:9087403]
experiment: EXISTENCE:direct assay:GO:0010499 proteasomal ubiquitin-independent protein catabolic process [PMID:19162040]
experiment: EXISTENCE:direct assay:GO:0019774 proteasome core complex, beta-subunit complex [PMID:9087403]
experiment: EXISTENCE:direct assay:GO:0034515 proteasome storage granule [PMID:18504300]
experiment: EXISTENCE:direct assay:GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process [PMID:11545745|PMID:19029916]
experiment: EXISTENCE:mutant phenotype:GO:0004175 endopeptidase activity [PMID:9207060|PMID:9312134]
note: Beta 1 subunit of the 20S proteasome; responsible for cleavage after acidic residues in peptides
codon start: 1
product: proteasome core particle subunit beta 1
translation: MNGIQVDINRLKKGEVSLGTSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSAADTQAIADIVQYHLELYTSQYGTPSTETAASVFKELCYENKDNLTAGIIVAGYDDKNKGEVYTIPLGGSVHKLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLSQAIKWDGSSGGVIRMVVLTAAGVERLIFYPDEYEQL
SIO_010081: YJL001W
subclass of: SO_0000673
so part of: YJL001W
location: join(435163..435227,435344..435926)
location: region:435163-435926:1
so has part: feature:435163-435227:1:exon
so has part: feature:435344-435926:1:exon

NP_012533.1
type: Protein
SIO_000068: ncbiprotein

S000003538
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:435163-435227:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:435344-435926:1:exon

centromere
type: Centromere
subclass of: SO_0000577
RO_0002162: 559292
note: CEN10; Chromosome X centromere
so part of: sequence
location: complement(436307..436425)
location: region:436307-436425:-1
so has part: feature:436307-436425:-1:region

S000006471
type: SGD
SIO_000068: sgd

position:436307:-1
position: 436307
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:436425:-1
position: 436425
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:436307-436425:-1:region

centromere
type: Centromere
subclass of: SO_0000577
RO_0002162: 559292
note: CEN10_CDEIII of CEN10
so part of: sequence
location: complement(436307..436331)
location: region:436307-436331:-1
so has part: feature:436307-436331:-1:region

position:436331:-1
position: 436331
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:436307-436331:-1:region

centromere
type: Centromere
subclass of: SO_0000577
RO_0002162: 559292
note: CEN10_CDEII of CEN10
so part of: sequence
location: complement(436332..436415)
location: region:436332-436415:-1
so has part: feature:436332-436415:-1:region

position:436332:-1
position: 436332
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:436415:-1
position: 436415
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:436332-436415:-1:region

centromere
type: Centromere
subclass of: SO_0000577
RO_0002162: 559292
note: CEN10_CDEI of CEN10
so part of: sequence
location: complement(436416..436425)
location: region:436416-436425:-1
so has part: feature:436416-436425:-1:region

position:436416:-1
position: 436416
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:436416-436425:-1:region

YJR001W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: AVT1
locus tag: YJR001W
so part of: sequence
location: <436802..>438610
location: region:436802-438610:1
so has part: feature:436802-438610:1:exon
subclass of: SO_0000010

853457
type: Gene
SIO_000068: ncbigene

position:436802:1
position: 436802
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:438610:1
position: 438610
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:436802-438610:1:exon

YJR001W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: AVT1
locus tag: YJR001W
product: Avt1p
transcript id: NM_001181658.1
SIO_010081: YJR001W
subclass of: SO_0000673
so part of: YJR001W
location: <436802..>438610
location: region:436802-438610:1
so has part: feature:436802-438610:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:436802-438610:1:exon

YJR001W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: AVT1
locus tag: YJR001W
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:11274162|PMID:27246536]
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0000329 fungal-type vacuole membrane [PMID:11274162]
experiment: EXISTENCE:mutant phenotype:GO:0003333 amino acid transmembrane transport [PMID:11274162]
experiment: EXISTENCE:mutant phenotype:GO:0005302 L-tyrosine transmembrane transporter activity [PMID:11274162]
experiment: EXISTENCE:mutant phenotype:GO:0006865 amino acid transport [PMID:11274162]
experiment: EXISTENCE:mutant phenotype:GO:0007034 vacuolar transport [PMID:11274162]
experiment: EXISTENCE:mutant phenotype:GO:0015186 L-glutamine transmembrane transporter activity [PMID:11274162]
experiment: EXISTENCE:mutant phenotype:GO:0015188 L-isoleucine transmembrane transporter activity [PMID:11274162]
experiment: EXISTENCE:mutant phenotype:GO:0015824 proline transport [PMID:27246536]
note: Vacuolar transporter; imports large neutral amino acids into vacuole; targeted to vacuole via AP-3 pathway; member of family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters
codon start: 1
product: Avt1p
translation: MPEQEPLSPNGRKRSEVHYISIPLNRGSAFSPDDSVSQFQSDGFMTRRQSILDHPVGSFKGVNSLSRFATSLRRANSFRNIELNADNERSFFKESNDETYDPDTLAPALDGRRLSVTLNNAGRPRITNLANNDRVSTASMAIHDDDYGSIQNSTIGDSGSILRPTASLTEMMSGGAGRRFTNNDMDSIVVKRVEGVDGKVVTLLAGQSTAPQTIFNSINVLIGIGLLALPLGLKYAGWVIGLTMLAIFALATFCTAELLSRCLDTDPTLISYADLGYAAFGTKGRALISALFTLDLLGSGVSLVILFGDSLNALFPQYSTTFFKIVSFFIVTPPVFIPLSVLSNISLLGILSTTGTVLVICCCGLYKSSSPGSLVNPMETSMWPIDLKHLCLSIGLLSACWGGHAVFPNLKTDMRHPDKFKDCLKTTYKITSVTDIGTAVIGFLMFGNLVKDEITKNVLLTEGYPKFVYGLISALMTIIPIAKTPLNARPIVSVLDVLMNVQHIDEAASAIKRRAAKGLQVFNRIFINVVFVLIAINFPEFDKIIAFLGAGLCFTICLILPCWFYLRLCKTTIKPWERVACHVTICISVVLSTLGVGAAIIS
SIO_010081: YJR001W
subclass of: SO_0000673
so part of: YJR001W
location: 436802..438610
location: region:436802-438610:1
so has part: feature:436802-438610:1:exon

NP_012534.1
type: Protein
SIO_000068: ncbiprotein

S000003761
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:436802-438610:1:exon

YJR002W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MPP10
locus tag: YJR002W
so part of: sequence
location: <438865..>440646
location: region:438865-440646:1
so has part: feature:438865-440646:1:exon
subclass of: SO_0000010

853458
type: Gene
SIO_000068: ncbigene

position:438865:1
position: 438865
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:440646:1
position: 440646
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:438865-440646:1:exon

YJR002W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MPP10
locus tag: YJR002W
product: rRNA-processing protein MPP10
transcript id: NM_001181659.3
SIO_010081: YJR002W
subclass of: SO_0000673
so part of: YJR002W
location: <438865..>440646
location: region:438865-440646:1
so has part: feature:438865-440646:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:438865-440646:1:exon

YJR002W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MPP10
locus tag: YJR002W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0030686 90S preribosome [PMID:12150911]
experiment: EXISTENCE:direct assay:GO:0032040 small-subunit processome [PMID:12068309]
experiment: EXISTENCE:direct assay:GO:0034457 Mpp10 complex [PMID:17515605]
experiment: EXISTENCE:mutant phenotype:GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:9315638]
experiment: EXISTENCE:mutant phenotype:GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:9315638]
experiment: EXISTENCE:mutant phenotype:GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:9315638]
experiment: EXISTENCE:mutant phenotype:GO:0032040 small-subunit processome [PMID:12242301]
note: Component of the SSU processome and 90S preribosome; required for pre-18S rRNA processing, interacts with and controls the stability of Imp3p and Imp4p, essential for viability; similar to human Mpp10p
codon start: 1
product: rRNA-processing protein MPP10
translation: MSELFGVLKSNAGRIILKDPSATSKDVKAYIDSVINTCKNGSITKKAELDEITVDGLDANQVWWQVKLVLDSIDGDLIQGIQELKDVVTPSHNLSDGSTLNSSSGEESELEEAESVFKEKQMLSADVSEIEEQSNDSLSENDEEPSMDDEKTSAEAAREEFAEEKRISSGQDERHSSPDPYGINDKFFDLEKFNRDTLAAEDSNEASEGSEDEDIDYFQDMPSDDEEEEAIYYEDFFDKPTKEPVKKHSDVKDPKEDEELDEEEHDSAMDKVKLDLFADEEDEPNAEGVGEASDKNLSSFEKQQIEIRKQIEQLENEAVAEKKWSLKGEVKAKDRPEDALLTEELEFDRTAKPVPVITSEVTESLEDMIRRRIQDSNFDDLQRRTLLDITRKSQRPQFELSDVKSSKSLAEIYEDDYTRAEDESALSEELQKAHSEISELYANLVYKLDVLSSVHFVPKPASTSLEIRVETPTISMEDAQPLYMSNASSLAPQEIYNVGKAEKDGEIRLKNGVAMSKEELTREDKNRLRRALKRKRSKANLPNVNKRSKRNDVVDTLSKAKNITVINQKGEKKDVSGKTKKSRSGPDSTNIKL
SIO_010081: YJR002W
subclass of: SO_0000673
so part of: YJR002W
location: 438865..440646
location: region:438865-440646:1
so has part: feature:438865-440646:1:exon

NP_012535.3
type: Protein
SIO_000068: ncbiprotein

S000003762
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:438865-440646:1:exon

YJR003C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MRX12
locus tag: YJR003C
so part of: sequence
location: complement(<440994..>442553)
location: region:440994-442553:-1
so has part: feature:440994-442553:-1:exon
subclass of: SO_0000010

853459
type: Gene
SIO_000068: ncbigene

position:440994:-1
position: 440994
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:442553:-1
position: 442553
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:440994-442553:-1:exon

YJR003C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MRX12
locus tag: YJR003C
product: Mrx12p
transcript id: NM_001181660.1
SIO_010081: YJR003C
subclass of: SO_0000673
so part of: YJR003C
location: complement(<440994..>442553)
location: region:440994-442553:-1
so has part: feature:440994-442553:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:440994-442553:-1:exon

YJR003C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MRX12
locus tag: YJR003C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095|PMID:16823961|PMID:24769239]
note: Protein that associates with mitochondrial ribosome; detected in highly purified mitochondria in high-throughput studies; predicted to be involved in ribosome biogenesis
codon start: 1
product: Mrx12p
translation: MLRSLHSAATLSNKRFYSLISHSNRKNIIKKLLRHPSFDPIRHHLPEDITTIDPYSLSQNVIESLNKLEVPKKDAAMVHNMMIENLSDLDYGVATIHSNNLRDLDLKPSLPAIKQIIRNNPGRVQSSWELFTQYKASMENVPDELMEVVLEKIIKFDKAEKVDGKKSLTYQDLVRCLYLINHFSSNYNLPSELVEPILIYIVDNGIPNVLGSVLKYKIPLSFFDKYVSEMTQYQICELYDFYSLDNIVADPLVLHKCLTVLGENEKIQQTEEEKEIISKLEEEIDIVKSQCHDNWSLEFPNWSVRKTATSFEELFLEIQKRNIDKKDFELAHKLLRLIGAFKGKVSLFFKLYDEYLLKFKNNEDDLMFEAFLTLCCQGYKSSNEKMLQYAEAFIKEDFDSKLESKIQSVLIVANAKANIDLSLKIYNSNISTAKREKDKYTDLAESDVLTESLILAFLSRDDADFARVIFDGALGEKLISGPTAAKKIKNLLAQYGEALETKTSKQVMQTKIEHYMESI
SIO_010081: YJR003C
subclass of: SO_0000673
so part of: YJR003C
location: complement(440994..442553)
location: region:440994-442553:-1
so has part: feature:440994-442553:-1:exon

NP_012536.2
type: Protein
SIO_000068: ncbiprotein

S000003763
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:440994-442553:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1015; Autonomously Replicating Sequence
so part of: sequence
location: 442556..442965
location: region:442556-442965:1
so has part: feature:442556-442965:1:region

S000028452
type: SGD
SIO_000068: sgd

position:442556:1
position: 442556
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:442965:1
position: 442965
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:442556-442965:1:region

YJR004C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: AG(ALPHA)1
gene: SAG1
locus tag: YJR004C
gene synonym: AG(ALPHA)1
so part of: sequence
location: complement(<442909..>444861)
location: region:442909-444861:-1
so has part: feature:442909-444861:-1:exon
subclass of: SO_0000010

853460
type: Gene
SIO_000068: ncbigene

position:442909:-1
position: 442909
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:444861:-1
position: 444861
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:442909-444861:-1:exon

YJR004C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: AG(ALPHA)1
gene: SAG1
locus tag: YJR004C
gene synonym: AG(ALPHA)1
product: Sag1p
transcript id: NM_001181661.1
SIO_010081: YJR004C
subclass of: SO_0000673
so part of: YJR004C
location: complement(<442909..>444861)
location: region:442909-444861:-1
so has part: feature:442909-444861:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:442909-444861:-1:exon

YJR004C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: AG(ALPHA)1
gene: SAG1
locus tag: YJR004C
gene synonym: AG(ALPHA)1
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0009277 fungal-type cell wall [PMID:10383953]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0000752 agglutination involved in conjugation with cellular fusion [PMID:2673555|PMID:2677666]
experiment: EXISTENCE:mutant phenotype:GO:0050839 cell adhesion molecule binding [PMID:11369849|PMID:2673555|PMID:2677666]
note: Alpha-agglutinin of alpha-cells; binds to Aga1p during agglutination, N-terminal half is homologous to the immunoglobulin superfamily and contains binding site for a-agglutinin, C-terminal half is highly glycosylated and contains GPI anchor
codon start: 1
product: Sag1p
translation: MFTFLKIILWLFSLALASAININDITFSNLEITPLTANKQPDQGWTATFDFSIADASSIREGDEFTLSMPHVYRIKLLNSSQTATISLADGTEAFKCYVSQQAAYLYENTTFTCTAQNDLSSYNTIDGSITFSLNFSDGGSSYEYELENAKFFKSGPMLVKLGNQMSDVVNFDPAAFTENVFHSGRSTGYGSFESYHLGMYCPNGYFLGGTEKIDYDSSNNNVDLDCSSVQVYSSNDFNDWWFPQSYNDTNADVTCFGSNLWITLDEKLYDGEMLWVNALQSLPANVNTIDHALEFQYTCLDTIANTTYATQFSTTREFIVYQGRNLGTASAKSSFISTTTTDLTSINTSAYSTGSISTVETGNRTTSEVISHVVTTSTKLSPTATTSLTIAQTSIYSTDSNITVGTDIHTTSEVISDVETISRETASTVVAAPTSTTGWTGAMNTYISQFTSSSFATINSTPIISSSAVFETSDASIVNVHTENITNTAAVPSEEPTFVNATRNSLNSFCSSKQPSSPSSYTSSPLVSSLSVSKTLLSTSFTPSVPTSNTYIKTKNTGYFEHTALTTSSVGLNSFSETAVSSQGTKIDTFLVSSLIAYPSSASGSQLSGIQQNFTSTSLMISTYEGKASIFFSAELGSIIFLLLSYLLF
SIO_010081: YJR004C
subclass of: SO_0000673
so part of: YJR004C
location: complement(442909..444861)
location: region:442909-444861:-1
so has part: feature:442909-444861:-1:exon

NP_012537.1
type: Protein
SIO_000068: ncbiprotein

S000003764
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:442909-444861:-1:exon

YJR005W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YAP80
gene: APL1
locus tag: YJR005W
gene synonym: YAP80
so part of: sequence
location: <445923..>448025
location: region:445923-448025:1
so has part: feature:445923-448025:1:exon
subclass of: SO_0000010

853461
type: Gene
SIO_000068: ncbigene

position:445923:1
position: 445923
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:448025:1
position: 448025
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:445923-448025:1:exon

YJR005W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YAP80
gene: APL1
locus tag: YJR005W
gene synonym: YAP80
product: Apl1p
transcript id: NM_001181662.3
SIO_010081: YJR005W
subclass of: SO_0000673
so part of: YJR005W
location: <445923..>448025
location: region:445923-448025:1
so has part: feature:445923-448025:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:445923-448025:1:exon

YJR005W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YAP80
gene: APL1
locus tag: YJR005W
gene synonym: YAP80
experiment: EXISTENCE:curator inference:GO:0016192 vesicle-mediated transport [PMID:22190733]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0030122 AP-2 adaptor complex [PMID:10564262]
experiment: EXISTENCE:direct assay:GO:0030139 endocytic vesicle [PMID:22190733]
note: Beta-adaptin; large subunit of the clathrin associated protein complex (AP-2); involved in vesicle mediated transport; similar to mammalian beta-chain of the clathrin associated protein complex
codon start: 1
product: Apl1p
translation: MSDQKVFARYKANEIVTDLQHFGVKKFKSNITRRKNALRKIIANLVLGNYGEMSVLFSELLKFWQIEDDLEVKRICHEYIRVIGALKPQQAREALPFIMDDFKSRDEKLQIMALRTLVLVPVKELSDQAFDCIISLVNHKSPPEQVTRTAIYALLDLDEIDHERVLGLSSILHDIVKAQSSSPEVIVAALHTLYSIHEKNANMEPFRIPLELAFDMLELLPELNEWNKATVLEVLTTSVVPQHYLDTHEMIELALPYLQQVNTYVVLNSLKFIMYLLNYVDVIKETLAEKLSNSVIALLDKPPELQFLVLRNVILLLLSRESSLLRLDISYFFIEYNDPIYIKDTKLECLYLLANKETLPRILEELEQYATDIDIQMSRKSVRAIGNLAVKLDEDSVHDCVAVLLDLLEFGVDYVVQEIISVFRNILRKYPNNFKANVTELVKHTEVVQEPESKNAMIWIITQYSDVIPNYLELFRVFSSNMFSETLEVQFSILNSAIKFFIRSPTKETEELCMDLLKGCIDHENNPDLRDKTLMYWRLLSLTKTSRISNAITFESLKSVLDGELPLIEMNTKLDPTVLEELELNIGTIVSIYLKPVSHIFRLNKTKLLPQSPILNPNKDLLPVVGNSFPPTGANRDRQNSESQSSTKSRKTAMMDDYDKPAEKINQLKGKRKSSSNNPSKLSRKPSTLLRKLSMKRPFS
SIO_010081: YJR005W
subclass of: SO_0000673
so part of: YJR005W
location: 445923..448025
location: region:445923-448025:1
so has part: feature:445923-448025:1:exon

NP_012538.3
type: Protein
SIO_000068: ncbiprotein

S000003765
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:445923-448025:1:exon

YJR005C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: LSO1
locus tag: YJR005C-A
so part of: sequence
location: complement(<448477..>448758)
location: region:448477-448758:-1
so has part: feature:448477-448758:-1:exon
subclass of: SO_0000010

1466469
type: Gene
SIO_000068: ncbigene

position:448477:-1
position: 448477
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:448758:-1
position: 448758
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:448477-448758:-1:exon

YJR005C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: LSO1
locus tag: YJR005C-A
product: Lso1p
transcript id: NM_001184533.1
SIO_010081: YJR005C-A
subclass of: SO_0000673
so part of: YJR005C-A
location: complement(<448477..>448758)
location: region:448477-448758:-1
so has part: feature:448477-448758:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:448477-448758:-1:exon

YJR005C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: LSO1
locus tag: YJR005C-A
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:26450372]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:26450372]
experiment: EXISTENCE:mutant phenotype:GO:0055072 iron ion homeostasis [PMID:26450372]
note: Protein with a potential role in response to iron deprivation; transcription increases during iron deprivation and during treatment with 2-(6-benzyl-2-pyridyl)quinazoline (BPQ) and copper; regulated by Aft1p and, to a lesser extent, by Aft2p; originally identified as a syntenic homolog of an Ashbya gossypii gene; localizes to nucleus and cytoplasm, and nuclear localization is enhanced under iron-replete conditions
codon start: 1
product: Lso1p
translation: MHNTGKRYSETAKKVAAGRARKRRQAYEKDQLEKQQLEAQEAQRWEEGARTPNQKKLIMEQKKTEKLRAKKERDQLLAAEEEALGKGGRGKRY
SIO_010081: YJR005C-A
subclass of: SO_0000673
so part of: YJR005C-A
location: complement(448477..448758)
location: region:448477-448758:-1
so has part: feature:448477-448758:-1:exon

NP_878106.1
type: Protein
SIO_000068: ncbiprotein

S000028523
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:448477-448758:-1:exon

YJR006W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: HUS2
alternative label: HYS2
alternative label: SDP5
gene: POL31
locus tag: YJR006W
gene synonym: HUS2; HYS2; SDP5
so part of: sequence
location: <449202..>450665
location: region:449202-450665:1
so has part: feature:449202-450665:1:exon
subclass of: SO_0000010

853462
type: Gene
SIO_000068: ncbigene

position:449202:1
position: 449202
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:450665:1
position: 450665
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:449202-450665:1:exon

YJR006W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: HUS2
alternative label: HYS2
alternative label: SDP5
gene: POL31
locus tag: YJR006W
gene synonym: HUS2; HYS2; SDP5
product: DNA-directed DNA polymerase delta subunit POL31
transcript id: NM_001181663.1
SIO_010081: YJR006W
subclass of: SO_0000673
so part of: YJR006W
location: <449202..>450665
location: region:449202-450665:1
so has part: feature:449202-450665:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:449202-450665:1:exon

YJR006W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: HUS2
alternative label: HYS2
alternative label: SDP5
gene: POL31
locus tag: YJR006W
gene synonym: HUS2; HYS2; SDP5
EC number: 2.7.7.7
experiment: EXISTENCE:direct assay:GO:0003887 DNA-directed DNA polymerase activity [PMID:18635534]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0006278 RNA-templated DNA biosynthetic process [PMID:17429354]
experiment: EXISTENCE:direct assay:GO:0016035 zeta DNA polymerase complex [PMID:23066099|PMID:22711820]
experiment: EXISTENCE:direct assay:GO:0043137 DNA replication, removal of RNA primer [PMID:16837458]
note: Subunit of DNA polymerase delta (polymerase III); essential for cell viability; involved in DNA replication and DNA repair; forms a complex with Rev3p, Rev7p and Pol32p; relocalizes to the cytosol in response to hypoxia
codon start: 1
product: DNA-directed DNA polymerase delta subunit POL31
translation: MDALLTKFNEDRSLQDENLSQPRTRVRIVDDNLYNKSNPFQLCYKKRDYGSQYYHIYQYRLKTFRERVLKECDKRWDAGFTLNGQLVLKKDKVLDIQGNQPCWCVGSIYCEMKYKPNVLDEVINDTYGAPDLTKSYTDKEGGSDEIMLEDESGRVLLVGDFIRSTPFITGVVVGILGMEAEAGTFQVLDICYPTPLPQNPFPAPIATCPTRGKIALVSGLNLNNTSPDRLLRLEILREFLMGRINNKIDDISLIGRLLICGNSVDFDIKSVNKDELMISLTEFSKFLHNILPSISVDIMPGTNDPSDKSLPQQPFHKSLFDKSLESYFNGSNKEILNLVTNPYEFSYNGVDVLAVSGKNINDICKYVIPSNDNGESENKVEEGESNDFKDDIEHRLDLMECTMKWQNIAPTAPDTLWCYPYTDKDPFVLDKWPHVYIVANQPYFGTRVVEIGGKNIKIISVPEFSSTGMIILLDLETLEAETVKIDI
SIO_010081: YJR006W
subclass of: SO_0000673
so part of: YJR006W
location: 449202..450665
location: region:449202-450665:1
so has part: feature:449202-450665:1:exon

NP_012539.1
type: Protein
SIO_000068: ncbiprotein

S000003766
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:449202-450665:1:exon

YJR007W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SUI2
locus tag: YJR007W
so part of: sequence
location: <451020..>451934
location: region:451020-451934:1
so has part: feature:451020-451934:1:exon
subclass of: SO_0000010

853463
type: Gene
SIO_000068: ncbigene

position:451020:1
position: 451020
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:451934:1
position: 451934
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:451020-451934:1:exon

YJR007W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SUI2
locus tag: YJR007W
product: translation initiation factor eIF2 subunit alpha
transcript id: NM_001181664.3
SIO_010081: YJR007W
subclass of: SO_0000673
so part of: YJR007W
location: <451020..>451934
location: region:451020-451934:1
so has part: feature:451020-451934:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:451020-451934:1:exon

YJR007W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SUI2
locus tag: YJR007W
experiment: EXISTENCE:direct assay:GO:0001731 formation of translation preinitiation complex [PMID:12008673]
experiment: EXISTENCE:direct assay:GO:0005525 GTP binding [PMID:14698289|PMID:16246727]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0010494 cytoplasmic stress granule [PMID:26777405]
experiment: EXISTENCE:direct assay:GO:0033290 eukaryotic 48S preinitiation complex [PMID:17242201]
experiment: EXISTENCE:direct assay:GO:0043614 multi-eIF complex [PMID:11018020|PMID:15838098]
experiment: EXISTENCE:direct assay:GO:1990856 methionyl-initiator methionine tRNA binding [PMID:16565414]
experiment: EXISTENCE:mutant phenotype:GO:0005850 eukaryotic translation initiation factor 2 complex [PMID:2649894]
note: Alpha subunit of the translation initiation factor eIF2; eIF2 is involved in identification of the start codon; phosphorylation of Ser51 is required for regulation of translation by inhibiting the exchange of GDP for GTP; protein abundance increases in response to DNA replication stress
codon start: 1
product: translation initiation factor eIF2 subunit alpha
translation: MSTSHCRFYENKYPEIDDIVMVNVQQIAEMGAYVKLLEYDNIEGMILLSELSRRRIRSIQKLIRVGKNDVAVVLRVDKEKGYIDLSKRRVSSEDIIKCEEKYQKSKTVHSILRYCAEKFQIPLEELYKTIAWPLSRKFGHAYEAFKLSIIDETVWEGIEPPSKDVLDELKNYISKRLTPQAVKIRADVEVSCFSYEGIDAIKDALKSAEDMSTEQMQVKVKLVAAPLYVLTTQALDKQKGIEQLESAIEKITEVITKYGGVCNITMPPKAVTATEDAELQALLESKELDNRSDSEDDEDESDDE
SIO_010081: YJR007W
subclass of: SO_0000673
so part of: YJR007W
location: 451020..451934
location: region:451020-451934:1
so has part: feature:451020-451934:1:exon

NP_012540.3
type: Protein
SIO_000068: ncbiprotein

S000003767
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:451020-451934:1:exon

YJR008W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MHO1
locus tag: YJR008W
so part of: sequence
location: <452430..>453446
location: region:452430-453446:1
so has part: feature:452430-453446:1:exon
subclass of: SO_0000010

853464
type: Gene
SIO_000068: ncbigene

position:452430:1
position: 452430
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:453446:1
position: 453446
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:452430-453446:1:exon

YJR008W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MHO1
locus tag: YJR008W
product: Mho1p
transcript id: NM_001181665.1
SIO_010081: YJR008W
subclass of: SO_0000673
so part of: YJR008W
location: <452430..>453446
location: region:452430-453446:1
so has part: feature:452430-453446:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:452430-453446:1:exon

YJR008W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MHO1
locus tag: YJR008W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22412880|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22412880|PMID:14562095]
note: hypothetical protein; inhibits haploid invasive growth when overexpressed; synthetically lethal with phospholipase C (PLC1); expression induced by mild heat-stress on a non-fermentable carbon source, upon entry into stationary phase and upon nitrogen deprivation; repressed by inosine and choline in an Opi1p-dependent manner; highly conserved from bacteria to human; Memo, the human homolog, is an ErbB2 interacting protein with an essential function in cell motility
codon start: 1
product: Mho1p
translation: MSIRPATHAGSWYSNRAQELSQQLHTYLIKSTLKGPIHNARIIICPHAGYRYCGPTMAYSYASLDLNRNVKRIFILGPSHHIYFKNQILVSAFSELETPLGNLKVDTDLCKTLIQKEYPENGKKLFKPMDHDTDMAEHSLEMQLPMLVETLKWREISLDTVKVFPMMVSHNSVDVDRCIGNILSEYIKDPNNLFIVSSDFCHWGRRFQYTGYVGSKEELNDAIQEETEVEMLTARSKLSHHQVPIWQSIEIMDRYAMKTLSDTPNGERYDAWKQYLEITGNTICGEKPISVILSALSKIRDAGPSGIKFQWPNYSQSSHVTSIDDSSVSYASGYVTIG
SIO_010081: YJR008W
subclass of: SO_0000673
so part of: YJR008W
location: 452430..453446
location: region:452430-453446:1
so has part: feature:452430-453446:1:exon

NP_012541.1
type: Protein
SIO_000068: ncbiprotein

S000003768
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:452430-453446:1:exon

YJR009C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: GLD2
gene: TDH2
locus tag: YJR009C
gene synonym: GLD2
so part of: sequence
location: complement(<453683..>454681)
location: region:453683-454681:-1
so has part: feature:453683-454681:-1:exon
subclass of: SO_0000010

853465
type: Gene
SIO_000068: ncbigene

position:453683:-1
position: 453683
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:454681:-1
position: 454681
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:453683-454681:-1:exon

YJR009C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: GLD2
gene: TDH2
locus tag: YJR009C
gene synonym: GLD2
product: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH2
transcript id: NM_001181666.1
SIO_010081: YJR009C
subclass of: SO_0000673
so part of: YJR009C
location: complement(<453683..>454681)
location: region:453683-454681:-1
so has part: feature:453683-454681:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:453683-454681:-1:exon

YJR009C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: GLD2
gene: TDH2
locus tag: YJR009C
gene synonym: GLD2
EC number: 1.2.1.12
experiment: EXISTENCE:direct assay:GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity [PMID:3905788]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16962558]
experiment: EXISTENCE:direct assay:GO:0005811 lipid droplet [PMID:10515935]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:11158358|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:16622836]
experiment: EXISTENCE:direct assay:GO:0009277 fungal-type cell wall [PMID:11158358]
experiment: EXISTENCE:direct assay:GO:1904408 melatonin binding [PMID:31708896]
experiment: EXISTENCE:direct assay:GO:1990841 promoter-specific chromatin binding [PMID:27184763]
experiment: EXISTENCE:expression pattern:GO:0006094 gluconeogenesis [PMID:3905788]
experiment: EXISTENCE:expression pattern:GO:0006096 glycolytic process [PMID:3905788]
experiment: EXISTENCE:mutant phenotype:GO:0006915 apoptotic process [PMID:17726063]
experiment: EXISTENCE:mutant phenotype:GO:0072593 reactive oxygen species metabolic process [PMID:17726063]
note: Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 2; involved in glycolysis and gluconeogenesis; tetramer that catalyzes reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in cytoplasm and cell wall; protein abundance increases in response to DNA replication stress; GAPDH-derived antimicrobial peptides are active against a wide variety of wine-related yeasts and bateria; TDH2 has a paralog, TDH3, that arose from the whole genome duplication
codon start: 1
product: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH2
translation: MVRVAINGFGRIGRLVMRIALQRKNVEVVALNDPFISNDYSAYMFKYDSTHGRYAGEVSHDDKHIIVDGHKIATFQERDPANLPWASLNIDIAIDSTGVFKELDTAQKHIDAGAKKVVITAPSSTAPMFVMGVNEEKYTSDLKIVSNASCTTNCLAPLAKVINDAFGIEEGLMTTVHSMTATQKTVDGPSHKDWRGGRTASGNIIPSSTGAAKAVGKVLPELQGKLTGMAFRVPTVDVSVVDLTVKLNKETTYDEIKKVVKAAAEGKLKGVLGYTEDAVVSSDFLGDSNSSIFDAAAGIQLSPKFVKLVSWYDNEYGYSTRVVDLVEHVAKA
SIO_010081: YJR009C
subclass of: SO_0000673
so part of: YJR009C
location: complement(453683..454681)
location: region:453683-454681:-1
so has part: feature:453683-454681:-1:exon

NP_012542.1
type: Protein
SIO_000068: ncbiprotein

S000003769
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:453683-454681:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1016; Autonomously Replicating Sequence
so part of: sequence
location: 454584..455555
location: region:454584-455555:1
so has part: feature:454584-455555:1:region

S000028453
type: SGD
SIO_000068: sgd

position:454584:1
position: 454584
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:455555:1
position: 455555
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:454584-455555:1:region

YJR010W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MET3
locus tag: YJR010W
so part of: sequence
location: <456239..>457774
location: region:456239-457774:1
so has part: feature:456239-457774:1:exon
subclass of: SO_0000010

853466
type: Gene
SIO_000068: ncbigene

position:456239:1
position: 456239
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:457774:1
position: 457774
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:456239-457774:1:exon

YJR010W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MET3
locus tag: YJR010W
product: sulfate adenylyltransferase
transcript id: NM_001181668.3
SIO_010081: YJR010W
subclass of: SO_0000673
so part of: YJR010W
location: <456239..>457774
location: region:456239-457774:1
so has part: feature:456239-457774:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:456239-457774:1:exon

YJR010W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MET3
locus tag: YJR010W
EC number: 2.7.7.4
experiment: EXISTENCE:direct assay:GO:0004781 sulfate adenylyltransferase (ATP) activity [PMID:10092498]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:14576278]
experiment: EXISTENCE:mutant phenotype:GO:0000096 sulfur amino acid metabolic process [PMID:1101032]
experiment: EXISTENCE:mutant phenotype:GO:0004781 sulfate adenylyltransferase (ATP) activity [PMID:197388]
experiment: EXISTENCE:mutant phenotype:GO:0019379 sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [PMID:197388]
note: ATP sulfurylase; catalyzes the primary step of intracellular sulfate activation, essential for assimilatory reduction of sulfate to sulfide, involved in methionine metabolism; human homolog PAPSS2 complements yeast null mutant
codon start: 1
product: sulfate adenylyltransferase
translation: MPAPHGGILQDLIARDALKKNELLSEAQSSDILVWNLTPRQLCDIELILNGGFSPLTGFLNENDYSSVVTDSRLADGTLWTIPITLDVDEAFANQIKPDTRIALFQDDEIPIAILTVQDVYKPNKTIEAEKVFRGDPEHPAISYLFNVAGDYYVGGSLEAIQLPQHYDYPGLRKTPAQLRLEFQSRQWDRVVAFQTRNPMHRAHRELTVRAAREANAKVLIHPVVGLTKPGDIDHHTRVRVYQEIIKRYPNGIAFLSLLPLAMRMSGDREAVWHAIIRKNYGASHFIVGRDHAGPGKNSKGVDFYGPYDAQELVESYKHELDIEVVPFRMVTYLPDEDRYAPIDQIDTTKTRTLNISGTELRRRLRVGGEIPEWFSYPEVVKILRESNPPRPKQGFSIVLGNSLTVSREQLSIALLSTFLQFGGGRYYKIFEHNNKTELLSLIQDFIGSGSGLIIPNQWEDDKDSVVGKQNVYLLDTSSSADIQLESADEPISHIVQKVVLFLEDNGFFVF
SIO_010081: YJR010W
subclass of: SO_0000673
so part of: YJR010W
location: 456239..457774
location: region:456239-457774:1
so has part: feature:456239-457774:1:exon

NP_012543.3
type: Protein
SIO_000068: ncbiprotein

S000003771
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:456239-457774:1:exon

YJR010C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SPC1
locus tag: YJR010C-A
so part of: sequence
location: complement(<458077..>458361)
location: region:458077-458361:-1
so has part: feature:458077-458361:-1:exon
subclass of: SO_0000010

853467
type: Gene
SIO_000068: ncbigene

position:458077:-1
position: 458077
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:458361:-1
position: 458361
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:458077-458361:-1:exon

YJR010C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SPC1
locus tag: YJR010C-A
product: signal peptidase complex subunit SPC1
transcript id: NM_001181667.1
SIO_010081: YJR010C-A
subclass of: SO_0000673
so part of: YJR010C-A
location: complement(<458077..>458361)
location: region:458077-458361:-1
so has part: feature:458077-458361:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:458077-458361:-1:exon

YJR010C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SPC1
locus tag: YJR010C-A
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005787 signal peptidase complex [PMID:1846444|PMID:8910564]
experiment: EXISTENCE:genetic interaction:GO:0006465 signal peptide processing [PMID:8663399]
experiment: EXISTENCE:genetic interaction:GO:0045047 protein targeting to ER [PMID:8663399]
experiment: EXISTENCE:mutant phenotype:GO:0006465 signal peptide processing [PMID:8663399]
experiment: EXISTENCE:physical interaction:GO:0045047 protein targeting to ER [PMID:8663399]
note: Subunit of the signal peptidase complex (SPC); SPC cleaves the signal sequence from proteins targeted to the endoplasmic reticulum (ER); homolog of the SPC12 subunit of mammalian signal peptidase complex; protein abundance increases in response to DNA replication stress
codon start: 1
product: signal peptidase complex subunit SPC1
translation: MSEILQDVQRKLVFPIDFPSQRKTEKFQQLSLMIGALVACILGFAQQSLKVLLTAYGISCVITLICVLPAYPWYNKQKLRWAQPKIEINVDQYD
SIO_010081: YJR010C-A
subclass of: SO_0000673
so part of: YJR010C-A
location: complement(458077..458361)
location: region:458077-458361:-1
so has part: feature:458077-458361:-1:exon

NP_012544.1
type: Protein
SIO_000068: ncbiprotein

S000003770
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:458077-458361:-1:exon

YJR011C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CAL4
locus tag: YJR011C
so part of: sequence
location: complement(<458641..>459426)
location: region:458641-459426:-1
so has part: feature:458641-459426:-1:exon
subclass of: SO_0000010

853468
type: Gene
SIO_000068: ncbigene

position:458641:-1
position: 458641
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:459426:-1
position: 459426
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:458641-459426:-1:exon

YJR011C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CAL4
locus tag: YJR011C
product: Cal4p
transcript id: NM_001181669.1
SIO_010081: YJR011C
subclass of: SO_0000673
so part of: YJR011C
location: complement(<458641..>459426)
location: region:458641-459426:-1
so has part: feature:458641-459426:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:458641-459426:-1:exon

YJR011C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CAL4
locus tag: YJR011C
note: Accessory component of the Ccr4-NOT complex; GFP-fusion protein expression is induced in response to the DNA-damaging agent MMS
codon start: 1
product: Cal4p
translation: MSETRESNESTVSSLQTKLLLNDGISENNKKNVILLNQIVPFILNTSHYMTDLMYVLYYLAQKQEDEVLNHSGTFISHKKELLALKSDICELIYDLRTGFRLLLDSCELDHFETPGKCRHLIEKVLVTSIYGVNRYIFQELNRLNVDFKDEFILQMQNCLSGFVNLYKFLNKIPMSKQQSQMNDLQMKILVNVLQNELLPIWKFQLDLLNCKLFNELSKDKGLINIYRKATNDSVIDVSKGEPFIRYVNWLKDQIIGEMTV
SIO_010081: YJR011C
subclass of: SO_0000673
so part of: YJR011C
location: complement(458641..459426)
location: region:458641-459426:-1
so has part: feature:458641-459426:-1:exon

NP_012545.1
type: Protein
SIO_000068: ncbiprotein

S000003772
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:458641-459426:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1017; Autonomously Replicating Sequence
so part of: sequence
location: 459337..459895
location: region:459337-459895:1
so has part: feature:459337-459895:1:region

S000028454
type: SGD
SIO_000068: sgd

position:459337:1
position: 459337
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:459895:1
position: 459895
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:459337-459895:1:region

YJR012C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJR012C
so part of: sequence
location: complement(<459795..>460193)
location: region:459795-460193:-1
so has part: feature:459795-460193:-1:exon
subclass of: SO_0000010

853469
type: Gene
SIO_000068: ncbigene

position:459795:-1
position: 459795
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:460193:-1
position: 460193
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:459795-460193:-1:exon

YJR012C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJR012C
product: uncharacterized protein
transcript id: NM_001181670.4
SIO_010081: YJR012C
subclass of: SO_0000673
so part of: YJR012C
location: complement(<459795..>460193)
location: region:459795-460193:-1
so has part: feature:459795-460193:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:459795-460193:-1:exon

YJR012C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJR012C
note: hypothetical protein; proposed involvement in transport based on mass spectrometry analysis of copurifying proteins; null mutant is viable
codon start: 1
product: uncharacterized protein
translation: MAAGGELSYEELLDHILNNKPIPNIVEVPNVTLDEGLASTPSLRPRPRPWEGQLQHQSHQGSLDKPNISLDIDQESLEGMTSLTRLSECYDIQSKLQINDSDNDNDDNNNDNNKGDGNDDDNNTVTANPTAR
SIO_010081: YJR012C
subclass of: SO_0000673
so part of: YJR012C
location: complement(459795..460193)
location: region:459795-460193:-1
so has part: feature:459795-460193:-1:exon

NP_012546.4
type: Protein
SIO_000068: ncbiprotein

S000003773
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:459795-460193:-1:exon

YJR013W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PMH1
gene: GPI14
locus tag: YJR013W
gene synonym: PMH1
so part of: sequence
location: <460382..>461593
location: region:460382-461593:1
so has part: feature:460382-461593:1:exon
subclass of: SO_0000010

853470
type: Gene
SIO_000068: ncbigene

position:460382:1
position: 460382
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:461593:1
position: 461593
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:460382-461593:1:exon

YJR013W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PMH1
gene: GPI14
locus tag: YJR013W
gene synonym: PMH1
product: glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I
transcript id: NM_001181671.1
SIO_010081: YJR013W
subclass of: SO_0000673
so part of: YJR013W
location: <460382..>461593
location: region:460382-461593:1
so has part: feature:460382-461593:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:460382-461593:1:exon

YJR013W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PMH1
gene: GPI14
locus tag: YJR013W
gene synonym: PMH1
experiment: EXISTENCE:direct assay:GO:0000030 mannosyltransferase activity [PMID:15635094]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0006506 GPI anchor biosynthetic process [PMID:16134120]
experiment: EXISTENCE:mutant phenotype:GO:0031505 fungal-type cell wall organization [PMID:16134120]
experiment: EXISTENCE:physical interaction:GO:0006506 GPI anchor biosynthetic process [PMID:15635094]
experiment: EXISTENCE:physical interaction:GO:1990529 glycosylphosphatidylinositol-mannosyltransferase I complex [PMID:15635094]
note: Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I; involved in GPI anchor biosynthesis, requires Pbn1p for function; homolog of mammalian PIG-M
codon start: 1
product: glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I
translation: MTGEEWGLTVLSFLVRVGFFLFGIYQDANFKVRYTDIDYFVFHDAAKYVYEGKSPYARDTYRYTPLLSWLLVPNHYFGWFHLGKVIFVIFDLVTGLIIMKLLNQAISRKRALILESIWLLNPMVITISTRGNAESVLCCLIMFTLFFLQKSRYTLAGILYGLSIHFKIYPIIYCIPIAIFIYYNKRNQGPRTQLTSLLNIGLSTLTTLLGCGWAMYKIYGYEFLDQAYLYHLYRTDHRHNFSVWNMLLYLDSANKENGESNLSRYAFVPQLLLVLVTGCLEWWNPTFDNLLRVLFVQTFAFVTYNKVCTSQYFVWYLIFLPFYLSRTHIGWKKGLLMATLWVGTQGIWLSQGYYLEFEGKNVFYPGLFIASVLFFVTNVWLLGQFITDIKIPTQPTVSNKKNN
SIO_010081: YJR013W
subclass of: SO_0000673
so part of: YJR013W
location: 460382..461593
location: region:460382-461593:1
so has part: feature:460382-461593:1:exon

NP_012547.2
type: Protein
SIO_000068: ncbiprotein

S000003774
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:460382-461593:1:exon

YJR014W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TMA22
locus tag: YJR014W
so part of: sequence
location: <461829..>462425
location: region:461829-462425:1
so has part: feature:461829-462425:1:exon
subclass of: SO_0000010

853471
type: Gene
SIO_000068: ncbigene

position:461829:1
position: 461829
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:462425:1
position: 462425
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:461829-462425:1:exon

YJR014W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TMA22
locus tag: YJR014W
product: Tma22p
transcript id: NM_001181672.1
SIO_010081: YJR014W
subclass of: SO_0000673
so part of: YJR014W
location: <461829..>462425
location: region:461829-462425:1
so has part: feature:461829-462425:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:461829-462425:1:exon

YJR014W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TMA22
locus tag: YJR014W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0032790 ribosome disassembly [PMID:34016977]
note: hypothetical protein; associates with ribosomes and has a putative RNA binding domain; interacts with Tma20p; similar to human GRAP and human DRP1, which interacts with human Tma20p homolog MCT-1; protein abundance increases in response to DNA replication stress
codon start: 1
product: Tma22p
translation: MLREVIYCGICSYPPEYCEFSGKLKRCKVWLSENHADLYAKLYGTDDNTQEVEAVTNKLAESSIGEAREEKLEKDLLKIQKKQENREQRELAKKLSSKVIIKREARTKRKFIVAISGLEVFDIDMKKLAKTFASRFATGCSVSKNAEKKEEVVIQGDVMDEVETYIHSLLEEKGLKDVKVETIDAKKKKKPAAEGAAK
SIO_010081: YJR014W
subclass of: SO_0000673
so part of: YJR014W
location: 461829..462425
location: region:461829-462425:1
so has part: feature:461829-462425:1:exon

NP_012548.1
type: Protein
SIO_000068: ncbiprotein

S000003775
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:461829-462425:1:exon

YJR015W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJR015W
so part of: sequence
location: <462721..>464253
location: region:462721-464253:1
so has part: feature:462721-464253:1:exon
subclass of: SO_0000010

853472
type: Gene
SIO_000068: ncbigene

position:462721:1
position: 462721
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:464253:1
position: 464253
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:462721-464253:1:exon

YJR015W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJR015W
product: uncharacterized protein
transcript id: NM_001181673.3
SIO_010081: YJR015W
subclass of: SO_0000673
so part of: YJR015W
location: <462721..>464253
location: region:462721-464253:1
so has part: feature:462721-464253:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:462721-464253:1:exon

YJR015W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJR015W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:14562095|PMID:26928762]
note: hypothetical protein; localizes to endoplasmic reticulum and cytoplasm; null mutant exhibits abnormal lipid metabolic phenotype; predicted to encode a membrane transporter based on phylogenetic analysis; not an essential gene; YJR015W has a paralog, SNG1, that arose from the whole genome duplication
codon start: 1
product: uncharacterized protein
translation: MTSSLDDIEPTAYNNMEADEEYCRRNDIHDLSSVVGDAVSQGVPDMDGQTTDSSKDPEPNSEDKKAFPPSSGSFFSPNLQGQRKKVLLKFVFTNCLLAIICFTMFVLFWGALYDTSKYLHKVKLLVVIQEPPVVILDNNSSMVVPSISYALPTFINKIPCDWDIYNSPTFQAKFDVNTPQQVNDKVVDLVYDEKYWFAINIKPNATETLFESLINDTAPLFNSTLFNQVVYETGRDPTNLKSTILPVAQTIEEYYHTFYTLNYLPPLLTNITQVYRYALTNNARYIAAAGKYNYEYYDHRPFTDRILLAPTQIGVVYCLLLTFFQFLLYGPLHVEMAKVLRPANGLIYRIAMSWFTFFFASLFFCTTTAIFQVDFTKSFGRGGFVVYWMSTWLFMLAAGGANENAVMLVITLGPQYLGFWILSFVILNIAPSFFPLALNNNVYRYGYMMPVHNVIDIYRVIFFDVTRRKMGRNYGILVALIALNTALLPFVGKYASRKLKQKALVAAKQS
SIO_010081: YJR015W
subclass of: SO_0000673
so part of: YJR015W
location: 462721..464253
location: region:462721-464253:1
so has part: feature:462721-464253:1:exon

NP_012549.3
type: Protein
SIO_000068: ncbiprotein

S000003776
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:462721-464253:1:exon

YJR016C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ILV3
locus tag: YJR016C
so part of: sequence
location: complement(<464451..>466208)
location: region:464451-466208:-1
so has part: feature:464451-466208:-1:exon
subclass of: SO_0000010

853473
type: Gene
SIO_000068: ncbigene

position:464451:-1
position: 464451
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:466208:-1
position: 466208
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:464451-466208:-1:exon

YJR016C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ILV3
locus tag: YJR016C
product: dihydroxy-acid dehydratase ILV3
transcript id: NM_001181674.1
SIO_010081: YJR016C
subclass of: SO_0000673
so part of: YJR016C
location: complement(<464451..>466208)
location: region:464451-466208:-1
so has part: feature:464451-466208:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:464451-466208:-1:exon

YJR016C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ILV3
locus tag: YJR016C
EC number: 4.2.1.9
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:24769239|PMID:16823961]
experiment: EXISTENCE:mutant phenotype:GO:0004160 dihydroxy-acid dehydratase activity [PMID:14124940]
experiment: EXISTENCE:mutant phenotype:GO:0009082 branched-chain amino acid biosynthetic process [PMID:14124940]
note: Dihydroxyacid dehydratase; putative 2Fe-2S protein; catalyzes third step in the common pathway leading to biosynthesis of branched-chain amino acids
codon start: 1
product: dihydroxy-acid dehydratase ILV3
translation: MGLLTKVATSRQFSTTRCVAKKLNKYSYIITEPKGQGASQAMLYATGFKKEDFKKPQVGVGSCWWSGNPCNMHLLDLNNRCSQSIEKAGLKAMQFNTIGVSDGISMGTKGMRYSLQSREIIADSFETIMMAQHYDANIAIPSCDKNMPGVMMAMGRHNRPSIMVYGGTILPGHPTCGSSKISKNIDIVSAFQSYGEYISKQFTEEEREDVVEHACPGPGSCGGMYTANTMASAAEVLGLTIPNSSSFPAVSKEKLAECDNIGEYIKKTMELGILPRDILTKEAFENAITYVVATGGSTNAVLHLVAVAHSAGVKLSPDDFQRISDTTPLIGDFKPSGKYVMADLINVGGTQSVIKYLYENNMLHGNTMTVTGDTLAERAKKAPSLPEGQEIIKPLSHPIKANGHLQILYGSLAPGGAVGKITGKEGTYFKGRARVFEEEGAFIEALERGEIKKGEKTVVVIRYEGPRGAPGMPEMLKPSSALMGYGLGKDVALLTDGRFSGGSHGFLIGHIVPEAAEGGPIGLVRDGDEIIIDADNNKIDLLVSDKEMAQRKQSWVAPPPRYTRGTLSKYAKLVSNASNGCVLDA
SIO_010081: YJR016C
subclass of: SO_0000673
so part of: YJR016C
location: complement(464451..466208)
location: region:464451-466208:-1
so has part: feature:464451-466208:-1:exon

NP_012550.1
type: Protein
SIO_000068: ncbiprotein

S000003777
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:464451-466208:-1:exon

YJR017C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PIN1
alternative label: PTF1
gene: ESS1
locus tag: YJR017C
gene synonym: PIN1; PTF1
so part of: sequence
location: complement(<466521..>467033)
location: region:466521-467033:-1
so has part: feature:466521-467033:-1:exon
subclass of: SO_0000010

853475
type: Gene
SIO_000068: ncbigene

position:466521:-1
position: 466521
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:467033:-1
position: 467033
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:466521-467033:-1:exon

YJR017C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PIN1
alternative label: PTF1
gene: ESS1
locus tag: YJR017C
gene synonym: PIN1; PTF1
product: peptidylprolyl isomerase ESS1
transcript id: NM_001181675.1
SIO_010081: YJR017C
subclass of: SO_0000673
so part of: YJR017C
location: complement(<466521..>467033)
location: region:466521-467033:-1
so has part: feature:466521-467033:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:466521-467033:-1:exon

YJR017C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PIN1
alternative label: PTF1
gene: ESS1
locus tag: YJR017C
gene synonym: PIN1; PTF1
EC number: 5.2.1.8
experiment: EXISTENCE:curator inference:GO:0005634 nucleus [PMID:10899126|PMID:10899127|PMID:14704159|PMID:10531363]
experiment: EXISTENCE:direct assay:GO:0003755 peptidyl-prolyl cis-trans isomerase activity [PMID:15728580|PMID:9867817]
experiment: EXISTENCE:direct assay:GO:0035307 positive regulation of protein dephosphorylation [PMID:11904169]
experiment: EXISTENCE:direct assay:GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain [PMID:22778132]
experiment: EXISTENCE:genetic interaction:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:14704159]
experiment: EXISTENCE:genetic interaction:GO:0006369 termination of RNA polymerase II transcription [PMID:19854134]
experiment: EXISTENCE:genetic interaction:GO:0045899 positive regulation of RNA polymerase II transcription preinitiation complex assembly [PMID:15166139]
experiment: EXISTENCE:genetic interaction:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:10899126]
experiment: EXISTENCE:mutant phenotype:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:14704159]
experiment: EXISTENCE:mutant phenotype:GO:0003755 peptidyl-prolyl cis-trans isomerase activity [PMID:15728580]
experiment: EXISTENCE:mutant phenotype:GO:0006369 termination of RNA polymerase II transcription [PMID:19854134|PMID:14704159|PMID:22778132]
experiment: EXISTENCE:mutant phenotype:GO:0031064 negative regulation of histone deacetylation [PMID:10899127]
experiment: EXISTENCE:mutant phenotype:GO:0035307 positive regulation of protein dephosphorylation [PMID:19854134]
experiment: EXISTENCE:mutant phenotype:GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process [PMID:19597489]
experiment: EXISTENCE:mutant phenotype:GO:2000749 positive regulation of rDNA heterochromatin formation [PMID:10899127]
experiment: EXISTENCE:physical interaction:GO:0000993 RNA polymerase II complex binding [PMID:10531363|PMID:10899126]
experiment: EXISTENCE:physical interaction:GO:0031064 negative regulation of histone deacetylation [PMID:10899127]
experiment: EXISTENCE:physical interaction:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:10899126]
note: Peptidylprolyl-cis/trans-isomerase (PPIase); specific for phosphorylated S/T residues N-terminal to proline; regulates phosphorylation of RNAPII large subunit (Rpo21p) C-terminal domain (CTD) at Ser7; associates with phospho-Ser5 form of RNAPII in vivo; present along entire coding length of genes; represses initiation of CUTs; required for efficient termination of mRNA transcription, trimethylation of histone H3; human ortholog PIN1 can complement yeast null and ts mutants
codon start: 1
product: peptidylprolyl isomerase ESS1
translation: MPSDVASRTGLPTPWTVRYSKSKKREYFFNPETKHSQWEEPEGTNKDQLHKHLRDHPVRVRCLHILIKHKDSRRPASHRSENITISKQDATDELKTLITRLDDDSKTNSFEALAKERSDCSSYKRGGDLGWFGRGEMQPSFEDAAFQLKVGEVSDIVESGSGVHVIKRVG
SIO_010081: YJR017C
subclass of: SO_0000673
so part of: YJR017C
location: complement(466521..467033)
location: region:466521-467033:-1
so has part: feature:466521-467033:-1:exon

NP_012551.2
type: Protein
SIO_000068: ncbiprotein

S000003778
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:466521-467033:-1:exon

YJR019C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PTE1
gene: TES1
locus tag: YJR019C
gene synonym: PTE1
so part of: sequence
location: complement(<467232..>468281)
location: region:467232-468281:-1
so has part: feature:467232-468281:-1:exon
subclass of: SO_0000010

853477
type: Gene
SIO_000068: ncbigene

position:467232:-1
position: 467232
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:468281:-1
position: 468281
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:467232-468281:-1:exon

YJR019C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PTE1
gene: TES1
locus tag: YJR019C
gene synonym: PTE1
product: palmitoyl-CoA hydrolase
transcript id: NM_001181677.3
SIO_010081: YJR019C
subclass of: SO_0000673
so part of: YJR019C
location: complement(<467232..>468281)
location: region:467232-468281:-1
so has part: feature:467232-468281:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:467232-468281:-1:exon

YJR019C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PTE1
gene: TES1
locus tag: YJR019C
gene synonym: PTE1
EC number: 3.1.2.2
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005777 peroxisome [PMID:10092594]
experiment: EXISTENCE:direct assay:GO:0047617 acyl-CoA hydrolase activity [PMID:10092594]
experiment: EXISTENCE:mutant phenotype:GO:0006635 fatty acid beta-oxidation [PMID:19830908]
experiment: EXISTENCE:mutant phenotype:GO:0019395 fatty acid oxidation [PMID:10092594]
note: Peroxisomal acyl-CoA thioesterase; likely to be involved in fatty acid oxidation rather than fatty acid synthesis; conserved protein also found in human peroxisomes; TES1 mRNA levels increase during growth on fatty acids
codon start: 1
product: palmitoyl-CoA hydrolase
translation: MSASKMAMSNLEKILELVPLSPTSFVTKYLPAAPVGSKGTFGGTLVSQSLLASLHTVPLNFFPTSLHSYFIKGGDPRTKITYHVQNLRNGRNFIHKQVSAYQHDKLIFTSMILFAVQRSKEHDSLQHWETIPGLQGKQPDPHRYEEATSLFQKEVLDPQKLSRYASLSDRFQDATSMSKYVDAFQYGVMEYQFPKDMFYSARHTDELDYFVKVRPPITTVEHAGDESSLHKHHPYRIPKSITPENDARYNYVAFAYLSDSYLLLTIPYFHNLPLYCHSFSVSLDHTIYFHQLPHVNNWIYLKISNPRSHWDKHLVQGKYFDTQSGRIMASVSQEGYVVYGSERDIRAKF
SIO_010081: YJR019C
subclass of: SO_0000673
so part of: YJR019C
location: complement(467232..468281)
location: region:467232-468281:-1
so has part: feature:467232-468281:-1:exon

NP_012553.3
type: Protein
SIO_000068: ncbiprotein

S000003780
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:467232-468281:-1:exon

YJR021C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MER2
gene: REC107
locus tag: YJR021C
gene synonym: MER2
so part of: sequence
location: complement(<468555..>469579)
location: region:468555-469579:-1
so has part: feature:468555-469579:-1:exon
subclass of: SO_0000010

853478
type: Gene
SIO_000068: ncbigene

position:468555:-1
position: 468555
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:469579:-1
position: 469579
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:468555-469579:-1:exon

YJR021C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MER2
gene: REC107
locus tag: YJR021C
gene synonym: MER2
product: Rec107p
transcript id: NM_001181679.1
SIO_010081: YJR021C
subclass of: SO_0000673
so part of: YJR021C
location: complement(join(<468555..469183,469264..>469579))
location: region:468555-469579:-1
so has part: feature:469264-469579:-1:exon
so has part: feature:468555-469183:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:469264-469579:-1:exon

position:469264:-1
position: 469264
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:468555-469183:-1:exon

position:469183:-1
position: 469183
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YJR021C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MER2
gene: REC107
locus tag: YJR021C
gene synonym: MER2
experiment: EXISTENCE:direct assay:GO:0000794 condensed nuclear chromosome [PMID:16783010]
experiment: EXISTENCE:mutant phenotype:GO:0007131 reciprocal meiotic recombination [PMID:8536989]
note: Protein involved in early stages of meiotic recombination; involved in coordination between the initiation of recombination and the first division of meiosis; part of a complex (Rec107p-Mei4p-Rec114p) required for ds break formation
codon start: 1
product: Rec107p
translation: MVARGRTDEISTDVSEANSEHSLMITETSSPFRSIFSHSGKVANAGALEESDKQILEWAGKLELESMELRENSDKLIKVLNENSKTLCKSLNKFNQLLEQDAATNGNVKTLIKDLASQIENQLDKVSTAMLSKGDEKKTKSDSSYRQVLVEEISRYNSKITRHVTNKQHETEKSMRCTQEMLFNVGSQLEDVHKVLLSLSKDMHSLQTRQTALEMAFREKADHAYDRPDVSLNGTTLLHDMDEAHDKQRKKSVPPPRMMVTRSMKRRRSSSPTLSTSQNHNSEDNDDASHRLKRAARTIIPWEELRPDTLESEL
SIO_010081: YJR021C
subclass of: SO_0000673
so part of: YJR021C
location: complement(join(468555..469183,469264..469579))
location: region:468555-469579:-1
so has part: feature:469264-469579:-1:exon
so has part: feature:468555-469183:-1:exon

NP_012555.1
type: Protein
SIO_000068: ncbiprotein

S000003782
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:469264-469579:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:468555-469183:-1:exon

YJR022W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: LSM8
locus tag: YJR022W
so part of: sequence
location: <469784..>470113
location: region:469784-470113:1
so has part: feature:469784-470113:1:exon
subclass of: SO_0000010

853479
type: Gene
SIO_000068: ncbigene

position:469784:1
position: 469784
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:470113:1
position: 470113
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:469784-470113:1:exon

YJR022W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: LSM8
locus tag: YJR022W
product: U4/U6-U5 snRNP complex subunit LSM8
transcript id: NM_001181680.1
SIO_010081: YJR022W
subclass of: SO_0000673
so part of: YJR022W
location: <469784..>470113
location: region:469784-470113:1
so has part: feature:469784-470113:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:469784-470113:1:exon

YJR022W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: LSM8
locus tag: YJR022W
experiment: EXISTENCE:direct assay:GO:0003723 RNA binding [PMID:10369684|PMID:15075370]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:12730603]
experiment: EXISTENCE:direct assay:GO:0005688 U6 snRNP [PMID:10369684|PMID:11720284]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:18029398]
experiment: EXISTENCE:direct assay:GO:0046540 U4/U6 x U5 tri-snRNP complex [PMID:10377396|PMID:10449419]
experiment: EXISTENCE:mutant phenotype:GO:0000398 mRNA splicing, via spliceosome [PMID:10428970]
note: Lsm (Like Sm) protein; forms heteroheptameric complex (with Lsm2p, Lsm3p, Lsm4p, Lsm5p, Lsm6p, and Lsm7p) that is part of spliceosomal U6 snRNP and is also implicated in processing of pre-tRNA, pre-snoRNA, and pre-rRNA
codon start: 1
product: U4/U6-U5 snRNP complex subunit LSM8
translation: MSATLKDYLNKRVVIIKVDGECLIASLNGFDKNTNLFITNVFNRISKEFICKAQLLRGSEIALVGLIDAENDDSLAPIDEKKVPMLKDTKNKIENEHVIWEKVYESKTK
SIO_010081: YJR022W
subclass of: SO_0000673
so part of: YJR022W
location: 469784..470113
location: region:469784-470113:1
so has part: feature:469784-470113:1:exon

NP_012556.2
type: Protein
SIO_000068: ncbiprotein

S000003783
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:469784-470113:1:exon

YJR024C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MDE1
locus tag: YJR024C
so part of: sequence
location: complement(<470230..>470964)
location: region:470230-470964:-1
so has part: feature:470230-470964:-1:exon
subclass of: SO_0000010

853481
type: Gene
SIO_000068: ncbigene

position:470230:-1
position: 470230
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:470964:-1
position: 470964
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:470230-470964:-1:exon

YJR024C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MDE1
locus tag: YJR024C
product: methylthioribulose 1-phosphate dehydratase MDE1
transcript id: NM_001181682.3
SIO_010081: YJR024C
subclass of: SO_0000673
so part of: YJR024C
location: complement(<470230..>470964)
location: region:470230-470964:-1
so has part: feature:470230-470964:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:470230-470964:-1:exon

YJR024C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MDE1
locus tag: YJR024C
EC number: 4.2.1.109
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0019509 L-methionine salvage from methylthioadenosine [PMID:18625006]
experiment: EXISTENCE:mutant phenotype:GO:0046570 methylthioribulose 1-phosphate dehydratase activity [PMID:18625006]
note: 5'-methylthioribulose-1-phosphate dehydratase; acts in the methionine salvage pathway; potential Smt3p sumoylation substrate; expression downregulated by caspofungin and deletion mutant is caspofungin resistant
codon start: 1
product: methylthioribulose 1-phosphate dehydratase MDE1
translation: MSSQDVLIHSDDPCHPANLICTLCKQFFHNNWCTGTGGGISIKDPNTNYYYLAPSGVQKEKMIPEDLFVMDAQTLEYLRSPKLYKPSACTPLFLACYQKKNAGAIIHTHSQNAVICSLLFGDEFRIANIEQIKAIPSGKVDPVTKKPMALSFFDTLKIPIIENMAHEDELIDDLHKTFKDYPDTCAVIVRRHGIFVWGPTIDKAKIFNEAIDYLMELAIKMYQMGIPPDCGIGEEKKHLKMASP
SIO_010081: YJR024C
subclass of: SO_0000673
so part of: YJR024C
location: complement(470230..470964)
location: region:470230-470964:-1
so has part: feature:470230-470964:-1:exon

NP_012558.3
type: Protein
SIO_000068: ncbiprotein

S000003785
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:470230-470964:-1:exon

YJR025C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: HAD1
gene: BNA1
locus tag: YJR025C
gene synonym: HAD1
so part of: sequence
location: complement(<471138..>471671)
location: region:471138-471671:-1
so has part: feature:471138-471671:-1:exon
subclass of: SO_0000010

853482
type: Gene
SIO_000068: ncbigene

position:471138:-1
position: 471138
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:471671:-1
position: 471671
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:471138-471671:-1:exon

YJR025C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: HAD1
gene: BNA1
locus tag: YJR025C
gene synonym: HAD1
product: 3-hydroxyanthranilate 3,4-dioxygenase
transcript id: NM_001181683.1
SIO_010081: YJR025C
subclass of: SO_0000673
so part of: YJR025C
location: complement(<471138..>471671)
location: region:471138-471671:-1
so has part: feature:471138-471671:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:471138-471671:-1:exon

YJR025C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: HAD1
gene: BNA1
locus tag: YJR025C
gene synonym: HAD1
EC number: 1.13.11.6
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11901108]
experiment: EXISTENCE:genetic interaction:GO:0034354 'de novo' NAD biosynthetic process from tryptophan [PMID:12062417]
experiment: EXISTENCE:mutant phenotype:GO:0000334 3-hydroxyanthranilate 3,4-dioxygenase activity [PMID:9539135]
note: 3-hydroxyanthranilic acid dioxygenase; required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expression regulated by Hst1p
codon start: 1
product: 3-hydroxyanthranilate 3,4-dioxygenase
translation: MFNTTPINIDKWLKENEGLLKPPVNNYCLHKGGFTVMIVGGPNERTGYHINPTPEWFYQKKGSMLLKVVDETDAEPKFIDIIINEGDSYLLPGNVPHSPVRFADTVGIVVEQDRPGGENDKIRWYCSHCRQVVHESELQMLDLGTQVKEAILDFENDVEKRTCFHCKTLNYARPQSN
SIO_010081: YJR025C
subclass of: SO_0000673
so part of: YJR025C
location: complement(471138..471671)
location: region:471138-471671:-1
so has part: feature:471138-471671:-1:exon

NP_012559.1
type: Protein
SIO_000068: ncbiprotein

S000003786
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:471138-471671:-1:exon

mobile_element
type: Mobile Element
subclass of: SO_0001037
RO_0002162: 559292
note: YJRWTy1-1; Ty1 element, LTR retrotransposon of the Copia (Pseudoviridae) group; contains co-transcribed genes TYA Gag and TYB Pol, encoding proteins involved in structure and function of virus-like particles, flanked by two direct repeats
mobile element type: retrotransposon:YJRWTy1-1
so part of: sequence
location: 472463..478384
location: region:472463-478384:1
so has part: feature:472463-478384:1:region

S000007048
type: SGD
SIO_000068: sgd

position:472463:1
position: 472463
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:478384:1
position: 478384
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:472463-478384:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 472463..472800
location: region:472463-472800:1
so has part: feature:472463-472800:1:region

S000007040
type: SGD
SIO_000068: sgd

position:472800:1
position: 472800
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:472463-472800:1:region

YJR027W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJR027W
so part of: sequence
location: <472760..>478028
location: region:472760-478028:1
so has part: feature:472760-478028:1:exon
subclass of: SO_0000010

853484
type: Gene
SIO_000068: ncbigene

position:472760:1
position: 472760
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:478028:1
position: 478028
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:472760-478028:1:exon

YJR027W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJR027W
product: gag-pol fusion protein
transcript id: NM_001181685.2
SIO_010081: YJR027W
subclass of: SO_0000673
so part of: YJR027W
location: <472760..>478028
location: region:472760-478028:1
so has part: feature:472760-478028:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:472760-478028:1:exon

YJR027W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJR027W
EC number: 2.7.7.7
EC number: 2.7.7.49
EC number: 3.1.26.4
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:9448009]
ribosomal slippage: true
note: Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes
codon start: 1
product: gag-pol fusion protein
translation: MESQQLSQHSHISHGSACASVTSKEVHTNQDPLDVSASKTEECEKASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNLSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQELTESTVNHTNHSDDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQDNTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVQYGDFYWVSKRYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNESDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKSAPSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSEYTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFSAIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLTASYQSFIASNEIQESNDLNIESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTEDSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISNIESTGSGGMHKLNVPLLAPMSQSNTHESSHASKSKDFRHSDSYSENETNHTNVPISSTGGTNNKTVPQISDQETEKRIIHRSPSIDASPPENNSSHNIVPIKTPTTVSEQNTEESIIADLPLPDLPPESPTEFPDPFKELPPINSHQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSLEPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLLKMKTWDTDEYYDRKEIDPKRVINSMFIFNKKRDGTHKARFVARGDIQHPDTYDTGMQSNTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLKKSHYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRGKYMKLGMENSLTEKIPKLNVPLNPKGRKLSAPGQPGLYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTEPDNKLVAISDASYGNQPYYKSQIGNIFLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSYLIQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYYIETKKNIADVMTKPLPIKTFKLLTNKWIH
SIO_010081: YJR027W
subclass of: SO_0000673
so part of: YJR027W
location: join(472760..474061,474063..478028)
location: region:472760-478028:1
so has part: feature:472760-474061:1:exon
so has part: feature:474063-478028:1:exon

NP_012560.1
type: Protein
SIO_000068: ncbiprotein

S000003788
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:472760-474061:1:exon

position:474061:1
position: 474061
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:474063-478028:1:exon

position:474063:1
position: 474063
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YJR026W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJR026W
so part of: sequence
location: <472760..>474082
location: region:472760-474082:1
so has part: feature:472760-474082:1:exon
subclass of: SO_0000010

853483
type: Gene
SIO_000068: ncbigene

position:474082:1
position: 474082
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:472760-474082:1:exon

YJR026W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJR026W
product: gag protein
transcript id: NM_001181684.3
SIO_010081: YJR026W
subclass of: SO_0000673
so part of: YJR026W
location: <472760..>474082
location: region:472760-474082:1
so has part: feature:472760-474082:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:472760-474082:1:exon

YJR026W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJR026W
note: Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag
codon start: 1
product: gag protein
translation: MESQQLSQHSHISHGSACASVTSKEVHTNQDPLDVSASKTEECEKASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNLSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPGTY
SIO_010081: YJR026W
subclass of: SO_0000673
so part of: YJR026W
location: 472760..474082
location: region:472760-474082:1
so has part: feature:472760-474082:1:exon

NP_012561.3
type: Protein
SIO_000068: ncbiprotein

S000003787
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:472760-474082:1:exon

mobile_element
type: Mobile Element
subclass of: SO_0001037
RO_0002162: 559292
note: YJRWTy1-2; Ty1 element, LTR retrotransposon of the Copia (Pseudoviridae) group; contains co-transcribed genes TYA Gag and TYB Pol, encoding proteins involved in structure and function of virus-like particles, flanked by two direct repeats
mobile element type: retrotransposon:YJRWTy1-2
so part of: sequence
location: 478051..483972
location: region:478051-483972:1
so has part: feature:478051-483972:1:region

S000007049
type: SGD
SIO_000068: sgd

position:478051:1
position: 478051
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:483972:1
position: 483972
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:478051-483972:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 478051..478384
location: region:478051-478384:1
so has part: feature:478051-478384:1:region

S000007041
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:478051-478384:1:region

YJR029W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJR029W
so part of: sequence
location: <478344..>483612
location: region:478344-483612:1
so has part: feature:478344-483612:1:exon
subclass of: SO_0000010

853486
type: Gene
SIO_000068: ncbigene

position:478344:1
position: 478344
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:483612:1
position: 483612
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:478344-483612:1:exon

YJR029W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJR029W
product: gag-pol fusion protein
transcript id: NM_001181687.2
SIO_010081: YJR029W
subclass of: SO_0000673
so part of: YJR029W
location: <478344..>483612
location: region:478344-483612:1
so has part: feature:478344-483612:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:478344-483612:1:exon

YJR029W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJR029W
EC number: 2.7.7.7
EC number: 2.7.7.49
EC number: 3.1.26.4
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:9448009]
ribosomal slippage: true
note: Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes
codon start: 1
product: gag-pol fusion protein
translation: MESQQLSQHSHISHGSACASVTSKEVHTNQDPLDVSASKTEECEKASTKANSQQTTTPASSAVPENPHHASPQTAQSHSPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQKLTESTVNHTNHSDDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQDNTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWVSKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNESDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKSAPSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSEYTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFSAIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLTASYQSFIASNEIQQSDDLNIESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTEDSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISNIESTGSGGMHKLNVPLLAPMSQSNTHESSHASKSKDFRHSDSYSENETNHTNVPISSTGGTNNKTVPQISDQETEKRIIHRSPSIDASPPENNSSHNIVPIKTPTTVSEQNTEESIIADLPLPDLPPESPTEFPDPFKELPPINSRQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSLEPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLLKMKTWDTDEYYDRKEIDPKRVINSMFIFNKKRDGTHKARFVARGDIQHPDTYDSGMQSNTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLKKSLYGLKQSGANWYETIKSYLIQQCGMEEVRGWSCVFKNSQVTICLFVDDMVLFSKNLNSNKRIIEKLKMQYDTKIINLGESDEEIQYDILGLEIKYQRGKYMKLGMENSLTEKIPKLNVPLNPKGRKLSAPGQPGLYIDQQELELEEDDYKMKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSKQVLDMTYELIQFIWNTRDKQLIWHKSKPVKPTNKLVVISDASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSYLIQELDKKPITKGLLTDSKSTISIIISNNEEKFRNRFFGTKAMRLRDEVSGNHLHVCYIETKKNIADVMTKPLPIKTFKLLTNKWIH
SIO_010081: YJR029W
subclass of: SO_0000673
so part of: YJR029W
location: join(478344..479644,479646..483612)
location: region:478344-483612:1
so has part: feature:478344-479644:1:exon
so has part: feature:479646-483612:1:exon

NP_012562.1
type: Protein
SIO_000068: ncbiprotein

S000003790
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:478344-479644:1:exon

position:479644:1
position: 479644
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:479646-483612:1:exon

position:479646:1
position: 479646
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YJR028W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJR028W
so part of: sequence
location: <478344..>479666
location: region:478344-479666:1
so has part: feature:478344-479666:1:exon
subclass of: SO_0000010

853485
type: Gene
SIO_000068: ncbigene

position:479666:1
position: 479666
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:478344-479666:1:exon

YJR028W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJR028W
product: gag protein
transcript id: NM_001181686.1
SIO_010081: YJR028W
subclass of: SO_0000673
so part of: YJR028W
location: <478344..>479666
location: region:478344-479666:1
so has part: feature:478344-479666:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:478344-479666:1:exon

YJR028W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJR028W
note: Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag
codon start: 1
product: gag protein
translation: MESQQLSQHSHISHGSACASVTSKEVHTNQDPLDVSASKTEECEKASTKANSQQTTTPASSAVPENPHHASPQTAQSHSPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPETY
SIO_010081: YJR028W
subclass of: SO_0000673
so part of: YJR028W
location: 478344..479666
location: region:478344-479666:1
so has part: feature:478344-479666:1:exon

NP_012563.1
type: Protein
SIO_000068: ncbiprotein

S000003789
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:478344-479666:1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 483635..483972
location: region:483635-483972:1
so has part: feature:483635-483972:1:region

S000007042
type: SGD
SIO_000068: sgd

position:483635:1
position: 483635
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:483635-483972:1:region

YJR030C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RBH2
locus tag: YJR030C
so part of: sequence
location: complement(<483959..>486196)
location: region:483959-486196:-1
so has part: feature:483959-486196:-1:exon
subclass of: SO_0000010

853487
type: Gene
SIO_000068: ncbigene

position:483959:-1
position: 483959
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:486196:-1
position: 486196
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:483959-486196:-1:exon

YJR030C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RBH2
locus tag: YJR030C
product: Rbh2p
transcript id: NM_001181688.3
SIO_010081: YJR030C
subclass of: SO_0000673
so part of: YJR030C
location: complement(<483959..>486196)
location: region:483959-486196:-1
so has part: feature:483959-486196:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:483959-486196:-1:exon

YJR030C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RBH2
locus tag: YJR030C
experiment: EXISTENCE:mutant phenotype:GO:0019320 hexose catabolic process [PMID:23185390]
note: hypothetical protein; expression repressed in carbon limited vs carbon replete chemostat cultures; non-essential gene; contains a PH-like domain; RBH2 has a paralog, RBH1, that arose from the whole genome duplication
codon start: 1
product: Rbh2p
translation: MELFNKEEASFETLLKRLLVVCESHSRYHGSSLDPMVKVGHEMRKISGYLRCILRKHAANHDDMSLTQSIVNSYKSLFKDAQILDLYHNLLFGCMHLLLDANMSYFRMDSQKLFAVLLFKVYYKLRDIFYVTNEVRLGSLISAFVYKFKSCYDFISCNSLKYGSVRDVISGEVSLINLPPIDSNKVINRAYYRLDVKKLAINNKLVEILELDNGEIAIFEVLSEKMPYTLQTIDNLFQSLALGNHDLMNVGRSLLFRPFRSGDLDLIRLDDSGAKLKVPINNSIVLRLTCKDPIQWQEYWKHVIRKLFDSTATKEYKRSGSKISQQVYVRSNNPDYTSPKRNDDMPISSVKISDTIHNGRTLHRSIPLPGSLSSLIETSNEYPDEESLSIMSERATVSEDSDLDTSLKDIESLSCEKLIELDKSIQVPLSPKYMDTPTLKNIRTASQTFSLESVSPELIESVASEIDDSESIISEDGKDKRDKDLFDPDIDFYKPTLYRRKSSSLLSIFSKNKKNLTIDIPKNHSRSLFSLPGNQQSVTPVSATPHDDNVDETYVSFPLSINTSGGAVYFENDSVKVSLWNGKSWVPLSKDMLCLSLILSGDNETLLIVYKDFEKEKCKLVVKLEPTWKYNRSTAQDVQLRIPSSDFKASVFGTLHDLTLSIRCAQAAKLVNVLQYQLQSSQTSSLSPSTTTGTLSTVSSSSCFSRNVTRSSTENSELANMKDSSEYISSSLLLSSVKVRQLRNM
SIO_010081: YJR030C
subclass of: SO_0000673
so part of: YJR030C
location: complement(483959..486196)
location: region:483959-486196:-1
so has part: feature:483959-486196:-1:exon

NP_012564.3
type: Protein
SIO_000068: ncbiprotein

S000003791
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:483959-486196:-1:exon

YJR031C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GEA1
locus tag: YJR031C
so part of: sequence
location: complement(<486586..>490812)
location: region:486586-490812:-1
so has part: feature:486586-490812:-1:exon
subclass of: SO_0000010

853488
type: Gene
SIO_000068: ncbigene

position:486586:-1
position: 486586
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:490812:-1
position: 490812
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:486586-490812:-1:exon

YJR031C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GEA1
locus tag: YJR031C
product: Arf family guanine nucleotide exchange factor GEA1
transcript id: NM_001181689.1
SIO_010081: YJR031C
subclass of: SO_0000673
so part of: YJR031C
location: complement(<486586..>490812)
location: region:486586-490812:-1
so has part: feature:486586-490812:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:486586-490812:-1:exon

YJR031C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GEA1
locus tag: YJR031C
experiment: EXISTENCE:direct assay:GO:0000137 Golgi cis cisterna [PMID:11294905]
experiment: EXISTENCE:direct assay:GO:0005085 guanyl-nucleotide exchange factor activity [PMID:10430582]
experiment: EXISTENCE:direct assay:GO:0005933 cellular bud [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [PMID:11294905]
experiment: EXISTENCE:genetic interaction:GO:0030036 actin cytoskeleton organization [PMID:14668359]
experiment: EXISTENCE:mutant phenotype:GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport [PMID:11493664|PMID:8945477]
experiment: EXISTENCE:mutant phenotype:GO:0006891 intra-Golgi vesicle-mediated transport [PMID:11493664]
experiment: EXISTENCE:mutant phenotype:GO:0016236 macroautophagy [PMID:20444982]
note: Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs); involved in vesicular transport between the Golgi and ER, Golgi organization, and actin cytoskeleton organization; GEA1 has a paralog, GEA2, that arose from the whole genome duplication
codon start: 1
product: Arf family guanine nucleotide exchange factor GEA1
translation: MHDVPMETVLAVNPATMIVKECINLCSAMNKQSRDKSQTSVAALLGGGSDIFLSQSDSFVDSFHNLPTSSYHDPLISGLVQLRLKINDLKGLDSLNALELLKPFLEIVSASSVSGYTTSLALDSLQKVFTLKIINKTFNDIQIAVRETVVALTHCRFEASKQISDDSVLLKVVTLLRDIITSSFGDYLSDTIIYDVLQTTLSLACNTQRSEVLRKTAEVTIAGITVKLFTKLKLLDPPTKTEKYINDESYTDNNLKDDIIGTTTSDNDLSSTDDDSAVADDNKNEKPVQQVIREQENDEETAEKAENVEPNYGITVIKDYLGLLLSLVMPENRMKHTTSAMKLSLQLINAAIEISGDKFPLYPRLFSLISDPIFKSVLFIIQSSTQYSLLQATLQLFTSLVVILGDYLPMQIELTLRRIFEILEDTTISGDVSKQKPPAIRELIIEQLSILWIHSPAFFLQLFVNFDCNLDRSDLSIDFIKELTKFSLPAAAVNTSNNIPPICLEGVLSLIENIYNDLQRFDRAEFVKNQKEIDILKQRDRKTEFILCVETFNEKAKKGIQMLIEKGFIDSDSNRDIASFLFLNNGRLNKKTIGLLLCDPKKTSLLKEFIDLFDFKGLRVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQSNDKVELEDKKAGKNGSESMTEDDIIHVQPDADSVFVLSYSIIMLNTDSHNPQVKDHMTFDDYSNNLRGCYNGKDFPRWYLHKIYTSIKVKEIVMPEEHHGNERWFEDAWNNLISSTSVMTEMQRDFTNPISKLAQIDILQYEKAIFSNVRDIILKTLFKIFTVASSDQISLRILDAISKCTFINYYFSFDQSYNDTVLHLGEMTTLAQSSAKAVELDVDSIPLVEIFVEDTGSKISVSNQSIRLGQNFKAQLCTVLYFQIIKEISDPSIVSTRLWNQIVQLILKLFENLLMEPNLPFFTNFHSLLKLPELPLPDPDISIRKAKMSRSLLSTFASYLKGDEEPSEEDIDFSIKAFECVKASHPLSSVFENNQLVSPKMIETLLSSLVIEKTSENSPYFEQELLFLLEISIILISEASYGQEFGALIADHMINISNLDGLSKEAIARLASYKMFLVSRFDNPRDILSDLIEHDFLVKNEIFNTKYYESEWGKQVINDLFTHLNDVKYNERALKNVKFWNFLRILISAKDRQFAVYTFLEKYIQNGDIFVDDGNFMNILSLLDEMSCAGAVGTKWEQNYENSVEDGCEAPESNPYRSIIDLSSRSINITADLLSTVGRSNSALNKNEIIAAIQGLAHQCLNPCDELGMQALQALENILLSRASQLRTEKVAVDNLLETGLLPIFELDEIQDVKMKRITSILSVLSKIFLGQLVEGVTSNETFLRVLNVFNKYVDDPTVERQLQELIISKREIEKE
SIO_010081: YJR031C
subclass of: SO_0000673
so part of: YJR031C
location: complement(486586..490812)
location: region:486586-490812:-1
so has part: feature:486586-490812:-1:exon

NP_012565.1
type: Protein
SIO_000068: ncbiprotein

S000003792
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:486586-490812:-1:exon

YJR032W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CPR7
locus tag: YJR032W
so part of: sequence
location: <491081..>492262
location: region:491081-492262:1
so has part: feature:491081-492262:1:exon
subclass of: SO_0000010

853489
type: Gene
SIO_000068: ncbigene

position:491081:1
position: 491081
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:492262:1
position: 492262
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:491081-492262:1:exon

YJR032W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CPR7
locus tag: YJR032W
product: peptidylprolyl isomerase CPR7
transcript id: NM_001181690.1
SIO_010081: YJR032W
subclass of: SO_0000673
so part of: YJR032W
location: <491081..>492262
location: region:491081-492262:1
so has part: feature:491081-492262:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:491081-492262:1:exon

YJR032W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CPR7
locus tag: YJR032W
EC number: 5.2.1.8
experiment: EXISTENCE:direct assay:GO:0003755 peptidyl-prolyl cis-trans isomerase activity [PMID:10942767]
experiment: EXISTENCE:direct assay:GO:0042026 protein refolding [PMID:10942767]
experiment: EXISTENCE:direct assay:GO:0051082 unfolded protein binding [PMID:10942767]
experiment: EXISTENCE:physical interaction:GO:0005829 cytosol [PMID:10942767]
note: Peptidyl-prolyl cis-trans isomerase (cyclophilin); catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds to Hsp82p and contributes to chaperone activity; plays a role in determining prion variants
codon start: 1
product: peptidylprolyl isomerase CPR7
translation: MIQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGVPESDVRISDCGVWEKTMGVPLYNASNDQIGGDVYEEYPDDDTHFGDDDFGKALEAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYLNLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKEKNPDDEVIEQRIEYVNRLIEENKEKTRKNISKFFS
SIO_010081: YJR032W
subclass of: SO_0000673
so part of: YJR032W
location: 491081..492262
location: region:491081-492262:1
so has part: feature:491081-492262:1:exon

NP_012566.1
type: Protein
SIO_000068: ncbiprotein

S000003793
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:491081-492262:1:exon

YJR033C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SOI3
gene: RAV1
locus tag: YJR033C
gene synonym: SOI3
so part of: sequence
location: complement(<492378..>496451)
location: region:492378-496451:-1
so has part: feature:492378-496451:-1:exon
subclass of: SO_0000010

853490
type: Gene
SIO_000068: ncbigene

position:492378:-1
position: 492378
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:496451:-1
position: 496451
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:492378-496451:-1:exon

YJR033C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SOI3
gene: RAV1
locus tag: YJR033C
gene synonym: SOI3
product: Rav1p
transcript id: NM_001181691.3
SIO_010081: YJR033C
subclass of: SO_0000673
so part of: YJR033C
location: complement(<492378..>496451)
location: region:492378-496451:-1
so has part: feature:492378-496451:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:492378-496451:-1:exon

YJR033C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SOI3
gene: RAV1
locus tag: YJR033C
gene synonym: SOI3
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11283612]
experiment: EXISTENCE:genetic interaction:GO:0007035 vacuolar acidification [PMID:11283612|PMID:11844802]
experiment: EXISTENCE:genetic interaction:GO:0043254 regulation of protein-containing complex assembly [PMID:11844802]
experiment: EXISTENCE:mutant phenotype:GO:0007035 vacuolar acidification [PMID:11283612|PMID:11844802]
experiment: EXISTENCE:mutant phenotype:GO:0043254 regulation of protein-containing complex assembly [PMID:11283612|PMID:11844802]
experiment: EXISTENCE:mutant phenotype:GO:0045022 early endosome to late endosome transport [PMID:15090613]
experiment: EXISTENCE:physical interaction:GO:0043254 regulation of protein-containing complex assembly [PMID:11283612]
experiment: EXISTENCE:physical interaction:GO:0043291 RAVE complex [PMID:11283612|PMID:11844802]
note: Subunit of RAVE complex (Rav1p, Rav2p, Skp1p); the RAVE complex promotes assembly of the V-ATPase holoenzyme; required for transport between the early and late endosome/PVC and for localization of TGN membrane proteins; potential Cdc28p substrate
codon start: 1
product: Rav1p
translation: MSLNFLPGRPNATPQTACQATWQNHTIFAYCSGNNLIILTNKFTRLQTIYTQSDCTAVDINSQNGFIALSFHNRVLIYKPIHQIMQNPKWTQCCQLFHDDTPVNCLRWSSDNELAIGSDFLSFWKIKDNFGVYQPILQWNQKQPKPVYNVIISQDSQLIVSIGKYDCNAKLWKRVSIVGEQAIFNLTMLPHPKPITAMRWKKEPDQVSKNNTASHALYTLCEDKVLRIWSCFEMEKNHTVQIWGEVPLSPTQKFCVIIDNWIIRQTLSVKDSEIFDISDSDIVILGSMTGEMEVLALNNLSQDPPKPMTKKTISHKKVKKATMLNDTRYLYLPEIQPYDNVKGKLSFLVHDLQGVIRHLLIDILQLINNKTEDLSAALEHKFTGHNKSVQKLVRSSDGEALLTTSRFSENGVWYPQKLNHGVSLRLQNTIQTESPIKFAVVHELGKQVICLLENGALQAWECPTNRKEDSEQKQSYLRVETRLKEEKKIHPIVMLNTPEPKHSHERHFTALIFSDGSIKAFEVSLTRGIFEVKSDSLDIDGDDIYKISIIDPVHQTFVSNRPLISLITKKGLTRTYKAIVNYNDRHVQWIKACEINTGIMNCTCIRGSSTGKLCIVNSTGKVMSLWDLNRGVLEYEETFHNPIEDIDWTSTEYGQSIVSIGFTGYALLYTQLRYDYTNNTPSYLPIEKIDITAHTAHNIGDSVWMKNGTFVVASGNQFYIKDKSLDLTDPFTYQSIGSRKILSNDILHLSSVLNGPLPVYHPQFLIQAIYANKLQLVKELLLRLFLALRKLDFESQDVSNLDSNLGMDPLKYFIAKDRDYPVESFPDPYPCFNKTVSLALTEQLTKTTLPYLTRHQQITLITVIEAVDEVTKNENIVDYNGVRFLLGVKLFLSHKNIQKSILMRDVSWALHSDNKEILLSSIDRHITSWNRAREYRIAYWIKEQDLVKKFEDIAKYEFSKDDKRDPSRCAIFYLALKKKQILLSLWKMAIGHPEQQKMVRFISNDFTVPRWRTAALKNAFVLLSKHRYMDAAVFFLLTDSLKDCVNVLCKQVHDMDLAIGVCRVYEGDNGPVLGELLTAQMLPETIKENDRWKASFIYWKLRKQEVAIKALLTAPIDLENNSSIVDKEVCVNRSFLVEDPALLYLYNHLRNRNLKYFIGSLNVEAKIECTLILRVTDILCRMGCNYLAVSLVKNWKFIERNSIPVQKLLKSPTKDRAYSAIGAMASEPISTARMRPSLFDKFGSPSASDIESPNPKLPNSLLDDFLQPPPNSTSSNSLAQSSSSAPRSILDEFVSPSYSQHKENLTPKAPNDSVGETDNSENRKDKLSKDILDDLSSQKPQKPKKSAITKNLLDDFV
SIO_010081: YJR033C
subclass of: SO_0000673
so part of: YJR033C
location: complement(492378..496451)
location: region:492378-496451:-1
so has part: feature:492378-496451:-1:exon

NP_012567.3
type: Protein
SIO_000068: ncbiprotein

S000003794
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:492378-496451:-1:exon

YJR034W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PET191
locus tag: YJR034W
so part of: sequence
location: <496683..>497009
location: region:496683-497009:1
so has part: feature:496683-497009:1:exon
subclass of: SO_0000010

853491
type: Gene
SIO_000068: ncbigene

position:496683:1
position: 496683
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:497009:1
position: 497009
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:496683-497009:1:exon

YJR034W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PET191
locus tag: YJR034W
product: Pet191p
transcript id: NM_001181692.1
SIO_010081: YJR034W
subclass of: SO_0000673
so part of: YJR034W
location: <496683..>497009
location: region:496683-497009:1
so has part: feature:496683-497009:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:496683-497009:1:exon

YJR034W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PET191
locus tag: YJR034W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005743 mitochondrial inner membrane [PMID:18503002]
experiment: EXISTENCE:direct assay:GO:0005758 mitochondrial intermembrane space [PMID:22984289]
experiment: EXISTENCE:mutant phenotype:GO:0033617 mitochondrial cytochrome c oxidase assembly [PMID:18503002|PMID:8381337]
note: Protein required for assembly of cytochrome c oxidase; exists as an oligomer; described as both an integral mitochondrial inner membrane protein facing the intermembrane space (IMS) and as a soluble IMS protein; contains a twin Cx9C motif; imported into the IMS via the MIA import machinery
codon start: 1
product: Pet191p
translation: MVASCKDQKKAVAICLQRSPCVMIERHNPQECLDNPELNKDLPELCIAQMKAFLDCKRGIVDMTKRFTGNAPLSTGKYDQQYENLCKGKFDPREEMEKLKLLNSQQKD
SIO_010081: YJR034W
subclass of: SO_0000673
so part of: YJR034W
location: 496683..497009
location: region:496683-497009:1
so has part: feature:496683-497009:1:exon

NP_012568.1
type: Protein
SIO_000068: ncbiprotein

S000003795
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:496683-497009:1:exon

YJR035W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RAD26
locus tag: YJR035W
so part of: sequence
location: <497355..>500612
location: region:497355-500612:1
so has part: feature:497355-500612:1:exon
subclass of: SO_0000010

853492
type: Gene
SIO_000068: ncbigene

position:497355:1
position: 497355
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:500612:1
position: 500612
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:497355-500612:1:exon

YJR035W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RAD26
locus tag: YJR035W
product: DNA-dependent ATPase RAD26
transcript id: NM_001181693.1
SIO_010081: YJR035W
subclass of: SO_0000673
so part of: YJR035W
location: <497355..>500612
location: region:497355-500612:1
so has part: feature:497355-500612:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:497355-500612:1:exon

YJR035W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RAD26
locus tag: YJR035W
EC number: 3.6.4.12
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0008094 ATP-dependent activity, acting on DNA [PMID:8702468]
experiment: EXISTENCE:genetic interaction:GO:0006283 transcription-coupled nucleotide-excision repair [PMID:17023424]
experiment: EXISTENCE:genetic interaction:GO:0006289 nucleotide-excision repair [PMID:17023424]
experiment: EXISTENCE:mutant phenotype:GO:0006283 transcription-coupled nucleotide-excision repair [PMID:7957102|PMID:32690696]
experiment: EXISTENCE:mutant phenotype:GO:0006357 regulation of transcription by RNA polymerase II [PMID:23991048]
note: Protein involved in transcription-coupled nucleotide excision repair; repairs UV-induced DNA lesions; recruitment to DNA lesions is dependent on an elongating RNA polymerase II; homolog of human CSB protein
codon start: 1
product: DNA-dependent ATPase RAD26
translation: MEDKEQQDNAKLENNESLKDLGVNVLSQSSLEEKIANDVTNFSNLQSLQQEETRLERSKTALQRYVNKKNHLTRKLNNTTRISVKQNLRDQIKNLQSDDIERVLKDIDDIQSRIKELKEQVDQGAENKGSKEGLQRPGETEKEFLIRTGKITAFGHKAGFSLDTANREYAKNDEQKDEDFEMATEQMVENLTDEDDNLSDQDYQMSGKESEDDEEEENDDKILKELEDLRFRGQPGEAKDDGDELYYQERLKKWVKQRSCGSQRSSDLPEWRRPHPNIPDAKLNSQFKIPGEIYSLLFNYQKTCVQWLYELYQQNCGGIIGDEMGLGKTIQVIAFIAALHHSGLLTGPVLIVCPATVMKQWCNEFQHWWPPLRTVILHSMGSGMASDQKFKMDENDLENLIMNSKPSDFSYEDWKNSTRTKKALESSYHLDKLIDKVVTDGHILITTYVGLRIHSDKLLKVKWQYAVLDEGHKIRNPDSEISLTCKKLKTHNRIILSGTPIQNNLTELWSLFDFIFPGKLGTLPVFQQQFVIPINIGGYANATNIQVQTGYKCAVALRDLISPYLLRRVKADVAKDLPQKKEMVLFCKLTKYQRSKYLEFLHSSDLNQIQNGKRNVLFGIDILRKICNHPDLLDRDTKRHNPDYGDPKRSGKMQVVKQLLLLWHKQGYKALLFTQSRQMLDILEEFISTKDPDLSHLNYLRMDGTTNIKGRQSLVDRFNNESFDVFLLTTRVGGLGVNLTGANRIIIFDPDWNPSTDMQARERAWRIGQKREVSIYRLMVGGSIEEKIYHRQIFKQFLTNRILTDPKQKRFFKIHELHDLFSLGGENGYSTEELNEEVQKHTENLKNSKSEESDDFEQLVNLSGVSKLESFYNGKEKKENSKTEDDRLIEGLLGGESNLETVMSHDSVVNSHAGSSSSNIITKEASRVAIEAVNALRKSRKKITKQYEIGTPTWTGRFGKAGKIRKRDPLKNKLTGSAAILGNITKSQKEASKEARQENYDDGITFARSKEINSNTKTLENIRAYLQKQNNFFSSSVSILNSIGVSLSDKEDVIKVRALLKTIAQFDKERKGWVLDEEFRNNNAS
SIO_010081: YJR035W
subclass of: SO_0000673
so part of: YJR035W
location: 497355..500612
location: region:497355-500612:1
so has part: feature:497355-500612:1:exon

NP_012569.1
type: Protein
SIO_000068: ncbiprotein

S000003796
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:497355-500612:1:exon

YJR036C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HUL4
locus tag: YJR036C
so part of: sequence
location: complement(<500713..>503391)
location: region:500713-503391:-1
so has part: feature:500713-503391:-1:exon
subclass of: SO_0000010

853494
type: Gene
SIO_000068: ncbigene

position:500713:-1
position: 500713
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:503391:-1
position: 503391
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:500713-503391:-1:exon

YJR036C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HUL4
locus tag: YJR036C
product: putative E3 ubiquitin-protein ligase HUL4
transcript id: NM_001181694.3
SIO_010081: YJR036C
subclass of: SO_0000673
so part of: YJR036C
location: complement(<500713..>503391)
location: region:500713-503391:-1
so has part: feature:500713-503391:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:500713-503391:-1:exon

YJR036C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: HUL4
locus tag: YJR036C
EC number: 2.3.2.26
experiment: EXISTENCE:direct assay:GO:0005628 prospore membrane [PMID:24390141]
experiment: EXISTENCE:direct assay:GO:0031499 TRAMP complex [PMID:15828860]
note: Protein with similarity to hect domain E3 ubiquitin-protein ligases; not essential for viability; found in association with Trf4 in TRAMP complex
codon start: 1
product: putative E3 ubiquitin-protein ligase HUL4
translation: MVSLFDKLNAKKDGRDGSVSKELLSHSVAHTKNRLPKSGRRTSERSLAASVKDGSCSNSKSNKRNSSASVSGEEDKSCLISLNCLCCGVPLRFPASITKFRCSACQVTVIVKEPEINSNLESSTHISCTLEGLQMVVRRCHDDLQRLKKTGILDKERKGLIFQPVITYLLDRFHDVSILNRSFLVHDGGKNIKMLNYEVLQRFYSILSNLPTRKPYYSMLCCCNDLLKRITINKGENLQILQYRWLLIILNIPTIRTCLIRDRKSKNVFETQQIRAVSYELAKRCIGYLSNLSTKTSQQLIQSLRRTPTDNFSYQVEILNLYINFQFSRLLSNELSNRTAKNNVKPEDEMRSRLRRHHTTGHEFLSTRPISAQSNDKQGSGFTHPVNNKMKFKFFQYEEDWHIHSAAKLTFIYYVANTRRNGRGALSIQSFYNITLDFIDYKQDFDHWRGVAQKTKMNQLIEEWGNSTTKKCFSFCKYPFILSLGIKISIMEYEIRRIMEHEAEQAFLISLDKGKSVDVYFKIKVRRDVISHDSLRCIKEHQGDLLKSLRIEFVNEPGIDAGGLRKEWFFLLTKSLFNPMNGLFIYIKESSRSWFAIDPPNFDKSKGKNSQLELYYLFGVVMGLAIFNSTILDLQFPKALYKKLCSEPLSFEDYSELFPETSRNLIKMLNYTEDNFEDVFSLTFETTYRNNNWILNDSKSSKEYVTVELCENGRNVPITQSNKHEFVMKWVEFYLEKSIEPQYNKFVSGFKRVFAECNSIKLFNSEELERLVCGDEEQTKFDFKSLRSVTKYVGGFSDDSRAVCWFWEIIESWDYPLQKKLLQFVTASDRIPATGISTIPFKISLLGSHDSDDLPLAHTCFNEICLWNYSSKKKLELKLLWAINESEGYGFR
SIO_010081: YJR036C
subclass of: SO_0000673
so part of: YJR036C
location: complement(500713..503391)
location: region:500713-503391:-1
so has part: feature:500713-503391:-1:exon

NP_012570.3
type: Protein
SIO_000068: ncbiprotein

S000003797
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:500713-503391:-1:exon

YJR039W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MLO127
locus tag: YJR039W
so part of: sequence
location: <503936..>507301
location: region:503936-507301:1
so has part: feature:503936-507301:1:exon
subclass of: SO_0000010

853495
type: Gene
SIO_000068: ncbigene

position:503936:1
position: 503936
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:507301:1
position: 507301
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:503936-507301:1:exon

YJR039W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MLO127
locus tag: YJR039W
product: Mlo127p
transcript id: NM_001181697.1
SIO_010081: YJR039W
subclass of: SO_0000673
so part of: YJR039W
location: <503936..>507301
location: region:503936-507301:1
so has part: feature:503936-507301:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:503936-507301:1:exon

YJR039W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MLO127
locus tag: YJR039W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
note: Mitochondrial hypothetical protein; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
codon start: 1
product: Mlo127p
translation: MPAGRIRIAMTDNIIVSEVDGPPDVVKCFIREEDGLEGQSRELVVIGLEYIDVFEGVEQDEARKKLRLRTVGYTMAAFYFKDHTAPNRRFYILLKATGRLDFVNLDYKIVKSLETGIDQVRSEPKFMFQDPLRTALVFNLSCTEIYEISTEDIFCLEETDVKLSYVTSSPIVSIDACINFNDFLDKDVFTLSILTRAHNEVAYKLEACVCVFESKPAKGTKWQRTTNLTFVEEATVSQVLLKSVTNIGHFVFTPWKTYFIKHALSSKQTIDGKTVDKIYQGPGAFGSDNMERIELLQPILADTTLNHLTFTFMTSTAILITCRMNAILSSFEDDTYIWEKALFERLPINGGSSHDHYLAAFFNEKCWILVSPKGHLTVYSVRNEGHSNFVHLGSFLCKSTLYSDLIGNYTKSHLSCGSLHCGQGYLCLKFRSCGDIFASTCMKLLFKSKDSVPRQVYSTRKGIYWADVNNNVYRDSERIDFEINGSFIATKDGTLLKDNTIVTLVPIQRDNECNYAYVTKQGYLRWSFSKVYYRIQNTGVDLTIDNCFLSAISSKGSFLTVLVLNDEITVFDHCNRLKSQKVVFHRLSDLASIFLYEYESTVYIFMSDTEGNLCVMKLATFEIVEEVKICKKKLQFCEVPNSDYFFIYTADTIIFFKPSKIKGRFKIQEVYAPCPISCLIPGEKDGSVVMVTSQGQFYDVLVPGDAGRATLCSKFEKVLKTCLKFITLESSSRYVIVAALPVANPLQDKYSEIYVYDIKQFKNISAFNFSNLNNDIESIKYENAMISDIIAVPMLKRTETLGKRKTSELYKEVIFNSCILVSLNLDSIDGIDSKNMNNLLLFSFDEESGFIEFVFGINTGFSISGLHNYYNGCVLVYGEFVQAYQLNYSVHDNKFSIEQVSNRLNISGITITSSIFFDKRKAKMARKQQNIGTWVYLEEMILLDVRKGVMRFNVIHTTDGNIEKVQLQVQPLNLFERDLINSITDTGKMFTGAAAITFKNIRYLLISYGDQKLTLFSLKLDGEEEIDERVYHVAEQVTTINSVRTTDSRMSTFLGESTFMPLFLVSTLSNGCYVIGILHEESDISLHILSEKKAVFAKRSVQKFLGFLDPQMDDHTVISEI
SIO_010081: YJR039W
subclass of: SO_0000673
so part of: YJR039W
location: 503936..507301
location: region:503936-507301:1
so has part: feature:503936-507301:1:exon

NP_012573.1
type: Protein
SIO_000068: ncbiprotein

S000003800
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:503936-507301:1:exon

YJR040W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CLC
gene: GEF1
locus tag: YJR040W
gene synonym: CLC
so part of: sequence
location: <507746..>510085
location: region:507746-510085:1
so has part: feature:507746-510085:1:exon
subclass of: SO_0000010

853497
type: Gene
SIO_000068: ncbigene

position:507746:1
position: 507746
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:510085:1
position: 510085
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:507746-510085:1:exon

YJR040W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CLC
gene: GEF1
locus tag: YJR040W
gene synonym: CLC
product: Gef1p
transcript id: NM_001181698.1
SIO_010081: YJR040W
subclass of: SO_0000673
so part of: YJR040W
location: <507746..>510085
location: region:507746-510085:1
so has part: feature:507746-510085:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:507746-510085:1:exon

YJR040W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CLC
gene: GEF1
locus tag: YJR040W
gene synonym: CLC
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:17662057]
experiment: EXISTENCE:direct assay:GO:0005247 voltage-gated chloride channel activity [PMID:12074596]
experiment: EXISTENCE:direct assay:GO:0005768 endosome [PMID:15710404]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:17662057]
experiment: EXISTENCE:direct assay:GO:0005794 Golgi apparatus [PMID:15710404]
experiment: EXISTENCE:direct assay:GO:0005797 Golgi medial cisterna [PMID:9614122]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:17662057]
experiment: EXISTENCE:mutant phenotype:GO:0006878 cellular copper ion homeostasis [PMID:9520490|PMID:9614122]
experiment: EXISTENCE:mutant phenotype:GO:0006879 cellular iron ion homeostasis [PMID:9520490]
note: Voltage-gated chloride channel; localized to the golgi, the endosomal system, and plasma membrane; involved in cation homeostasis; highly homologous to vertebrate voltage-gated chloride channels; modulates TBSV model (+) RNA virus replication by regulating copper metabolism
codon start: 1
product: Gef1p
translation: MPTTYVPINQPIGDGEDVIDTNRFTNIPETQNFDQFVTIDKIAEENRPLSVDSDREFLNSKYRHYREVIWDRAKTFITLSSTAIVIGCIAGFLQVFTETLVNWKTGHCQRNWLLNKSFCCNGVVNEVTSTSNLLLKRQEFECEAQGLWIAWKGHVSPFIIFMLLSVLFALISTLLVKYVAPMATGSGISEIKVWVSGFEYNKEFLGFLTLVIKSVALPLAISSGLSVGKEGPSVHYATCCGYLLTKWLLRDTLTYSSQYEYITAASGAGVAVAFGAPIGGVLFGLEEIASANRFNSSTLWKSYYVALVAITTLKYIDPFRNGRVILFNVTYDRDWKVQEIPIFIALGIFGGLYGKYISKWNINFIHFRKMYLSSWPVQEVLFLATLTALISYFNEFLKLDMTESMGILFHECVKNDNTSTFSHRLCQLDENTHAFEFLKIFTSLCFATVIRALLVVVSYGARVPAGIFVPSMAVGATFGRAVSLLVERFISGPSVITPGAYAFLGAAATLSGITNLTLTVVVIMFELTGAFMYIIPLMIVVAITRIILSTSGISGGIADQMIMVNGFPYLEDEQDEEEEETLEKYTAEQLMSSKLITINETIYLSELESLLYDSASEYSVHGFPITKDEDKFEKEKRCIGYVLKRHLASKIMMQSVNSTKAQTTLVYFNKSNEELGHRENCIGFKDIMNESPISVKKAVPVTLLFRMFKELGCKTIIVEESGILKGLVTAKDILRFKRIKYREVHGAKFTYNEALDRRCWSVIHFIIKRFTTNRNGNVI
SIO_010081: YJR040W
subclass of: SO_0000673
so part of: YJR040W
location: 507746..510085
location: region:507746-510085:1
so has part: feature:507746-510085:1:exon

NP_012574.1
type: Protein
SIO_000068: ncbiprotein

S000003801
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:507746-510085:1:exon

YJR041C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: NPA2
gene: URB2
locus tag: YJR041C
gene synonym: NPA2
so part of: sequence
location: complement(<510239..>513763)
location: region:510239-513763:-1
so has part: feature:510239-513763:-1:exon
subclass of: SO_0000010

853498
type: Gene
SIO_000068: ncbigene

position:510239:-1
position: 510239
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:513763:-1
position: 513763
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:510239-513763:-1:exon

YJR041C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: NPA2
gene: URB2
locus tag: YJR041C
gene synonym: NPA2
product: Urb2p
transcript id: NM_001181699.3
SIO_010081: YJR041C
subclass of: SO_0000673
so part of: YJR041C
location: complement(<510239..>513763)
location: region:510239-513763:-1
so has part: feature:510239-513763:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:510239-513763:-1:exon

YJR041C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: NPA2
gene: URB2
locus tag: YJR041C
gene synonym: NPA2
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:15226434|PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0016072 rRNA metabolic process [PMID:15242642]
experiment: EXISTENCE:physical interaction:GO:0042254 ribosome biogenesis [PMID:15226434]
note: Protein required for normal metabolism of the rRNA primary transcript; nucleolar protein; proposed to be involved in ribosome biogenesis
codon start: 1
product: Urb2p
translation: MGDLTEELSIPDNAQDLSKLLRSTSTKPHQIAEIVSKFDKLETYFPKKEIFVLDLLIDRLNNGNLDDFKTSEHTWIIFTRLLDAINDPISIKKLLKKLKTVPVMIRTFFLWPKDKLLTRSVSFIKAFFAINDYLIVNFSVEESFQLLEHAINGLSSCPTTDFALSYLQDACNLTHVDNITTTDNKIATCYCKHMLLPSLRYFAQTKNSASSNQSFIRLSHFMGKFLLQPRIDYMKLNKKFVQENASEITDDMAYYYFATFVTFLSKDNFAQLEVIFTILGAKKPSLECRFLNLLSESKKTVSQEFLEALLLEMLASTDESGVLSLIPIILKLDIEVAIKHIFRLLELIQLENLNDPLFSSHIWDLIIQSHANARELSDFFAKINEYCSRKGPDSYFLINHPAYVKSITKQLFTLSSLQWKNLLQALLDQVNHDSTNRVPLYLIRICLEGLSEGASRATLDEVKPILSQVFTLESFNNSLQWDLKYHIMEVYDDIVPAEELEKIDYVLSSNIFDTTSADVEELFFYCFKLREYISFDLSDAKKKFMRHFEILDEERKSNLSYSVVSKFATLVNNNFTREQISSLIDSLLLNSTNLSSLLKNDDIFEETNITYALINKLASSYHQTFALEALIQIPIQCINKNVRVALINNLTCESFCLDSATRECLLHLLSSPTFKSNIETNFYELCEKTIMSPEMAISETGDEKKEIEDKISIFEKVWTNHLSQAKEPVSEKFLESGYDIVKQSMSLSNGDSKLIIAGFTIAKFLKPDNKHRDIQGMAISYAVKILENYSENFESETIPLFRISMSTLYKIITTGQGDISKHKSRILDIFSKIMLRYHSKKVYHAPEEQEMFLVHSLLTENKLEYIFAEYLNIEHTDKCDSALGFCLEESLKQGPDAFNRLLWNSAKSFSTISQPCAEKFVRVFIIMSKRIARDNNLGHHLFVIALLEAYTYCDIEKFGYKSYLLLFNAIKEFLVSKPWLFSQYCIEMLLPFCLKTLAFIVNHESTDEINEGFINIIEVIDHMLLVHRFKFSNRHHLFNSVLCQILEIIAIHDGTLCANSADAVARLITNYCEPYNVSNAQNGQKNNLSSKISLIKQSIRKNVLVVLTKYIQLSITTQFSLNIKKSLQPGIHAIFDILSQNELNQLNAFLDTPGKQYFKALYLQYKKVGKWRED
SIO_010081: YJR041C
subclass of: SO_0000673
so part of: YJR041C
location: complement(510239..513763)
location: region:510239-513763:-1
so has part: feature:510239-513763:-1:exon

NP_012575.3
type: Protein
SIO_000068: ncbiprotein

S000003802
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:510239-513763:-1:exon

YJR042W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RAT9
gene: NUP85
locus tag: YJR042W
gene synonym: RAT9
so part of: sequence
location: <514055..>516289
location: region:514055-516289:1
so has part: feature:514055-516289:1:exon
subclass of: SO_0000010

853499
type: Gene
SIO_000068: ncbigene

position:514055:1
position: 514055
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:516289:1
position: 516289
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:514055-516289:1:exon

YJR042W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RAT9
gene: NUP85
locus tag: YJR042W
gene synonym: RAT9
product: Nup85p
transcript id: NM_001181700.1
SIO_010081: YJR042W
subclass of: SO_0000673
so part of: YJR042W
location: <514055..>516289
location: region:514055-516289:1
so has part: feature:514055-516289:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:514055-516289:1:exon

YJR042W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RAT9
gene: NUP85
locus tag: YJR042W
gene synonym: RAT9
experiment: EXISTENCE:direct assay:GO:0005643 nuclear pore [PMID:10684247]
experiment: EXISTENCE:direct assay:GO:0031080 nuclear pore outer ring [PMID:11823431|PMID:18046406]
experiment: EXISTENCE:direct assay:GO:0045893 positive regulation of DNA-templated transcription [PMID:15817685]
experiment: EXISTENCE:mutant phenotype:GO:0000055 ribosomal large subunit export from nucleus [PMID:11071906]
experiment: EXISTENCE:mutant phenotype:GO:0006406 mRNA export from nucleus [PMID:8816998|PMID:8565072]
experiment: EXISTENCE:mutant phenotype:GO:0006606 protein import into nucleus [PMID:12730220]
experiment: EXISTENCE:mutant phenotype:GO:0017056 structural constituent of nuclear pore [PMID:22331846]
experiment: EXISTENCE:mutant phenotype:GO:0051664 nuclear pore localization [PMID:8816998|PMID:8565072]
note: Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC); contributes to nucleocytoplasmic transport and NPC biogenesis and is involved in establishment of a normal nucleocytoplasmic concentration gradient of the GTPase Gsp1p; also plays roles in several processes that may require localization of genes or chromosomes at the nuclear periphery, including double-strand break repair, transcription and chromatin silencing; homologous to human NUP85 aka NUP75
codon start: 1
product: Nup85p
translation: MTIDDSNRLLMDVDQFDFLDDGTAQLSNNKTDEEEQLYKRDPVSGAILVPMTVNDQPIEKNGDKMPLKFKLGPLSYQNMAFITAKDKYKLYPVRIPRLDTSKEFSAYVSGLFEIYRDLGDDRVFNVPTIGVVNSNFAKEHNATVNLAMEAILNELEVFIGRVKDQDGRVNRFYELEESLTVLNCLRTMYFILDGQDVEENRSEFIESLLNWINRSDGEPDEEYIEQVFSVKDSTAGKKVFETQYFWKLLNQLVLRGLLSQAIGCIERSDLLPYLSDTCAVSFDAVSDSIELLKQYPKDSSSTFREWKNLVLKLSQAFGSSATDISGELRDYIEDFLLVIGGNQRKILQYSRTWYESFCGFLLYYIPSLELSAEYLQMSLEANVVDITNDWEQPCVDIISGKIHSILPVMESLDSCTAAFTAMICEAKGLIENIFEGEKNSDDYSNEDNEMLEDLFSYRNGMASYMLNSFAFELCSLGDKELWPVAIGLIALSATGTRSAKKMVIAELLPHYPFVTNDDIEWMLSICVEWRLPEIAKEIYTTLGNQMLSAHNIIESIANFSRAGKYELVKSYSWLLFEASCMEGQKLDDPVLNAIVSKNSPAEDDVIIPQDILDCVVTNSMRQTLAPYAVLSQFYELRDREDWGQALRLLLLLIEFPYLPKHYLVLLVAKFLYPIFLLDDKKLMDEDSVATVIEVIETKWDDADEKSSNLYETIIEADKSLPSSMATLLKNLRKKLNFKLCQAFM
SIO_010081: YJR042W
subclass of: SO_0000673
so part of: YJR042W
location: 514055..516289
location: region:514055-516289:1
so has part: feature:514055-516289:1:exon

NP_012576.1
type: Protein
SIO_000068: ncbiprotein

S000003803
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:514055-516289:1:exon

YJR043C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: REV5
gene: POL32
locus tag: YJR043C
gene synonym: REV5
so part of: sequence
location: complement(<516461..>517513)
location: region:516461-517513:-1
so has part: feature:516461-517513:-1:exon
subclass of: SO_0000010

853500
type: Gene
SIO_000068: ncbigene

position:516461:-1
position: 516461
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:517513:-1
position: 517513
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:516461-517513:-1:exon

YJR043C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: REV5
gene: POL32
locus tag: YJR043C
gene synonym: REV5
product: DNA polymerase delta subunit POL32
transcript id: NM_001181701.1
SIO_010081: YJR043C
subclass of: SO_0000673
so part of: YJR043C
location: complement(<516461..>517513)
location: region:516461-517513:-1
so has part: feature:516461-517513:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:516461-517513:-1:exon

YJR043C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: REV5
gene: POL32
locus tag: YJR043C
gene synonym: REV5
experiment: EXISTENCE:direct assay:GO:0003887 DNA-directed DNA polymerase activity [PMID:18635534]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0006278 RNA-templated DNA biosynthetic process [PMID:17429354]
experiment: EXISTENCE:direct assay:GO:0016035 zeta DNA polymerase complex [PMID:22711820|PMID:23066099]
experiment: EXISTENCE:direct assay:GO:0043137 DNA replication, removal of RNA primer [PMID:16837458]
experiment: EXISTENCE:mutant phenotype:GO:0000727 double-strand break repair via break-induced replication [PMID:17671506]
experiment: EXISTENCE:mutant phenotype:GO:0006277 DNA amplification [PMID:23271978]
experiment: EXISTENCE:mutant phenotype:GO:0042276 error-prone translesion synthesis [PMID:17681555]
note: Third subunit of DNA polymerase delta; involved in chromosomal DNA replication; required for error-prone DNA synthesis in the presence of DNA damage and processivity; forms a complex with Rev3p, Rev7p and Pol31p; interacts with Hys2p, PCNA (Pol30p), and Pol1p
codon start: 1
product: DNA polymerase delta subunit POL32
translation: MDQKASYFINEKLFTEVKPVLFTDLIHHLKIGPSMAKKLMFDYYKQTTNAKYNCVVICCYKDQTIKIIHDLSNIPQQDSIIDCFIYAFNPMDSFIPYYDIIDQKDCLTIKNSYELKVSESSKIIERTKTLEEKSKPLVRPTARSKTTPEETTGRKSKSKDMGLRSTALLAKMKKDRDDKETSRQNELRKRKEENLQKINKQNPEREAQMKELNNLFVEDDLDTEEVNGGSKPNSPKETDSNDKDKNNDDLEDLLETTAEDSLMDVPKIQQTKPSETEHSKEPKSEEEPSSFIDEDGYIVTKRPATSTPPRKPSPVVKRALSSSKKQETPSSNKRLKKQGTLESFFKRKAK
SIO_010081: YJR043C
subclass of: SO_0000673
so part of: YJR043C
location: complement(516461..517513)
location: region:516461-517513:-1
so has part: feature:516461-517513:-1:exon

NP_012577.1
type: Protein
SIO_000068: ncbiprotein

S000003804
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:516461-517513:-1:exon

YNCJ0022C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: IMT3
locus tag: YNCJ0022C
so part of: sequence
location: complement(517813..517884)
location: region:517813-517884:-1
so has part: feature:517813-517884:-1:exon
subclass of: SO_0000663

853501
type: Gene
SIO_000068: ncbigene

position:517813:-1
position: 517813
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:517884:-1
position: 517884
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:517813-517884:-1:exon

YNCJ0022C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
gene: IMT3
locus tag: YNCJ0022C
product: tRNA-Met
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006413 translational initiation [PMID:9023104]
experiment: EXISTENCE:direct assay:GO:0016282 eukaryotic 43S preinitiation complex [PMID:12008673]
experiment: EXISTENCE:direct assay:GO:0033290 eukaryotic 48S preinitiation complex [PMID:17242201]
experiment: EXISTENCE:direct assay:GO:0071074 eukaryotic initiation factor eIF2 binding [PMID:14698289]
note: Methionine initiator tRNA (tRNA-Met); predicted by tRNAscan-SE analysis; one of four initiator methionine tRNAs in yeast that are functional for translation
SIO_010081: YNCJ0022C
subclass of: SO_0000673
so part of: YNCJ0022C
location: complement(517813..517884)
location: region:517813-517884:-1
so has part: feature:517813-517884:-1:exon

S000006663
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:517813-517884:-1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 517959..518099
location: region:517959-518099:1
so has part: feature:517959-518099:1:region

S000007043
type: SGD
SIO_000068: sgd

position:517959:1
position: 517959
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:518099:1
position: 518099
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:517959-518099:1:region

YJR044C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: VPS55
locus tag: YJR044C
so part of: sequence
location: complement(<518763..>519185)
location: region:518763-519185:-1
so has part: feature:518763-519185:-1:exon
subclass of: SO_0000010

853502
type: Gene
SIO_000068: ncbigene

position:518763:-1
position: 518763
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:519185:-1
position: 519185
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:518763-519185:-1:exon

YJR044C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: VPS55
locus tag: YJR044C
product: Vps55p
transcript id: NM_001181702.3
SIO_010081: YJR044C
subclass of: SO_0000673
so part of: YJR044C
location: complement(<518763..>519185)
location: region:518763-519185:-1
so has part: feature:518763-519185:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:518763-519185:-1:exon

YJR044C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: VPS55
locus tag: YJR044C
experiment: EXISTENCE:direct assay:GO:0005770 late endosome [PMID:12006663]
experiment: EXISTENCE:direct assay:GO:0034424 Vps55/Vps68 complex [PMID:18216282]
experiment: EXISTENCE:mutant phenotype:GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway [PMID:18216282]
experiment: EXISTENCE:physical interaction:GO:0034424 Vps55/Vps68 complex [PMID:18216282]
note: Late endosomal protein involved in late endosome to vacuole transport; functional homolog of human obesity receptor gene-related protein (OB-RGRP)
codon start: 1
product: Vps55p
translation: MMEFKVSPLTKIISLSGFLALGFLLVILSCALFHNYYPLFDILIFLLAPIPNTIFNAGNKYHTSDFMSDSSNTGQDLAHFLTGMLVTSGIALPVVFYHCQLIGHLSCIMCMIGGLIIYSSIVIFKWFFKKDFNEDDSLFG
SIO_010081: YJR044C
subclass of: SO_0000673
so part of: YJR044C
location: complement(518763..519185)
location: region:518763-519185:-1
so has part: feature:518763-519185:-1:exon

NP_012578.3
type: Protein
SIO_000068: ncbiprotein

S000003805
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:518763-519185:-1:exon

YJR045C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ENS1
gene: SSC1
locus tag: YJR045C
gene synonym: ENS1
so part of: sequence
location: complement(<519638..>521602)
location: region:519638-521602:-1
so has part: feature:519638-521602:-1:exon
subclass of: SO_0000010

853503
type: Gene
SIO_000068: ncbigene

position:519638:-1
position: 519638
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:521602:-1
position: 521602
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:519638-521602:-1:exon

YJR045C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ENS1
gene: SSC1
locus tag: YJR045C
gene synonym: ENS1
product: Hsp70 family ATPase SSC1
transcript id: NM_001181703.1
SIO_010081: YJR045C
subclass of: SO_0000673
so part of: YJR045C
location: complement(<519638..>521602)
location: region:519638-521602:-1
so has part: feature:519638-521602:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:519638-521602:-1:exon

YJR045C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ENS1
gene: SSC1
locus tag: YJR045C
gene synonym: ENS1
EC number: 3.6.4.10
experiment: EXISTENCE:direct assay:GO:0001405 PAM complex, Tim23 associated import motor [PMID:14517234|PMID:14638855]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:11914276|PMID:24769239|PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005743 mitochondrial inner membrane [PMID:7935837]
experiment: EXISTENCE:direct assay:GO:0016887 ATP hydrolysis activity [PMID:11096111]
experiment: EXISTENCE:direct assay:GO:0030150 protein import into mitochondrial matrix [PMID:8654364]
experiment: EXISTENCE:direct assay:GO:0030234 enzyme regulator activity [PMID:10464305]
experiment: EXISTENCE:direct assay:GO:0032079 positive regulation of endodeoxyribonuclease activity [PMID:10464305]
experiment: EXISTENCE:direct assay:GO:0042026 protein refolding [PMID:9973563]
experiment: EXISTENCE:direct assay:GO:0042645 mitochondrial nucleoid [PMID:15692048]
experiment: EXISTENCE:mutant phenotype:GO:0030150 protein import into mitochondrial matrix [PMID:10779357]
experiment: EXISTENCE:mutant phenotype:GO:0042026 protein refolding [PMID:16460754]
experiment: EXISTENCE:mutant phenotype:GO:0043335 protein unfolding [PMID:8408192]
note: Hsp70 family ATPase; constituent of the import motor component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); involved in protein translocation and folding; subunit of SceI endonuclease; SSC1 has a paralog, ECM10, that arose from the whole genome duplication
codon start: 1
product: Hsp70 family ATPase SSC1
translation: MLAAKNILNRSSLSSSFRIATRLQSTKVQGSVIGIDLGTTNSAVAIMEGKVPKIIENAEGSRTTPSVVAFTKEGERLVGIPAKRQAVVNPENTLFATKRLIGRRFEDAEVQRDIKQVPYKIVKHSNGDAWVEARGQTYSPAQIGGFVLNKMKETAEAYLGKPVKNAVVTVPAYFNDSQRQATKDAGQIVGLNVLRVVNEPTAAALAYGLEKSDSKVVAVFDLGGGTFDISILDIDNGVFEVKSTNGDTHLGGEDFDIYLLREIVSRFKTETGIDLENDRMAIQRIREAAEKAKIELSSTVSTEINLPFITADASGPKHINMKFSRAQFETLTAPLVKRTVDPVKKALKDAGLSTSDISEVLLVGGMSRMPKVVETVKSLFGKDPSKAVNPDEAVAIGAAVQGAVLSGEVTDVLLLDVTPLSLGIETLGGVFTRLIPRNTTIPTKKSQIFSTAAAGQTSVEIRVFQGERELVRDNKLIGNFTLAGIPPAPKGVPQIEVTFDIDADGIINVSARDKATNKDSSITVAGSSGLSENEIEQMVNDAEKFKSQDEARKQAIETANKADQLANDTENSLKEFEGKVDKAEAQKVRDQITSLKELVARVQGGEEVNAEELKTKTEELQTSSMKLFEQLYKNDSNNNNNNNGNNAESGETKQ
SIO_010081: YJR045C
subclass of: SO_0000673
so part of: YJR045C
location: complement(519638..521602)
location: region:519638-521602:-1
so has part: feature:519638-521602:-1:exon

NP_012579.1
type: Protein
SIO_000068: ncbiprotein

S000003806
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:519638-521602:-1:exon

YJR046W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CDT1
alternative label: SID2
gene: TAH11
locus tag: YJR046W
gene synonym: CDT1; SID2
so part of: sequence
location: <522048..>523862
location: region:522048-523862:1
so has part: feature:522048-523862:1:exon
subclass of: SO_0000010

853504
type: Gene
SIO_000068: ncbigene

position:522048:1
position: 522048
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:523862:1
position: 523862
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:522048-523862:1:exon

YJR046W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CDT1
alternative label: SID2
gene: TAH11
locus tag: YJR046W
gene synonym: CDT1; SID2
product: Tah11p
transcript id: NM_001181704.1
SIO_010081: YJR046W
subclass of: SO_0000673
so part of: YJR046W
location: <522048..>523862
location: region:522048-523862:1
so has part: feature:522048-523862:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:522048-523862:1:exon

YJR046W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CDT1
alternative label: SID2
gene: TAH11
locus tag: YJR046W
gene synonym: CDT1; SID2
experiment: EXISTENCE:direct assay:GO:0003688 DNA replication origin binding [PMID:16824194]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:11836525]
experiment: EXISTENCE:direct assay:GO:0005656 nuclear pre-replicative complex [PMID:16824194]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11836525]
experiment: EXISTENCE:direct assay:GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication [PMID:16824194]
experiment: EXISTENCE:direct assay:GO:0030174 regulation of DNA-templated DNA replication initiation [PMID:11967159]
experiment: EXISTENCE:mutant phenotype:GO:0000727 double-strand break repair via break-induced replication [PMID:20516198]
experiment: EXISTENCE:mutant phenotype:GO:0005656 nuclear pre-replicative complex [PMID:11967159]
note: DNA replication licensing factor; required for pre-replication complex assembly
codon start: 1
product: Tah11p
translation: MSGTANSRRKEVLRVPVIDLNRVSDEEQLLPVVRAILLQHDTFLLKNYANKAVLDALLAGLTTKDLPDTSQGFDANFTGTLPLEDDVWLEQYIFDTDPQLRFDRKCRNESLCSIYSRLFKLGLFFAQLCVKSVVSSAELQDCISTSHYATKLTRYFNDNGSTHDGADAGATVLPTGDDFQYLFERDYVTFLPTGVLTIFPCAKAIRYKPSTMATTDNSWVSIDEPDCLLFHTGTLLARWSQGMHTTSPLQIDPRANIVSLTIWPPLTTPISSKGEGTIANHLLEQQIKAFPKVAQQYYPRELSILRLQDAMKFVKELFTVCETVLSLNALSRSTGVPPELHVLLPQISSMMKRKIVQDDILKLLTIWSDAYVVELNSRGELTMNLPKRDNLTTLTNKSRTLAFVERAESWYQQVIASKDEIMTDVPAFKINKRRSSSNSKTVLSSKVQTKSSNANALNNSRYLANSKENFMYKEKMPDSQANLMDRLRERERRSAALLSQRQKRYQQFLAMKMTQVFDILFSLTRGQPYTETYLSSLIVDSLQDSNNPIGTKEASEILAGLQGILPMDISVHQVDGGLKVYRWNSLDKNRFSKLLQIHKSKQQD
SIO_010081: YJR046W
subclass of: SO_0000673
so part of: YJR046W
location: 522048..523862
location: region:522048-523862:1
so has part: feature:522048-523862:1:exon

NP_012580.1
type: Protein
SIO_000068: ncbiprotein

S000003807
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:522048-523862:1:exon

YNCJ0023C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCJ0023C
so part of: sequence
location: complement(524012..524093)
location: region:524012-524093:-1
so has part: feature:524012-524093:-1:exon
subclass of: SO_0000663

853505
type: Gene
SIO_000068: ncbigene

position:524012:-1
position: 524012
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:524093:-1
position: 524093
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:524012-524093:-1:exon

YNCJ0023C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCJ0023C
product: tRNA-Ser
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
experiment: EXISTENCE:direct assay:GO:0030371 translation repressor activity [PMID:27609601]
experiment: EXISTENCE:direct assay:GO:0043022 ribosome binding [PMID:27609601]
experiment: EXISTENCE:direct assay:GO:0043555 regulation of translation in response to stress [PMID:27609601]
note: Serine tRNA (tRNA-Ser), predicted by tRNAscan-SE analysis
SIO_010081: YNCJ0023C
subclass of: SO_0000673
so part of: YNCJ0023C
location: complement(524012..524093)
location: region:524012-524093:-1
so has part: feature:524012-524093:-1:exon

S000006727
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:524012-524093:-1:exon

YJR047C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: HYP1
alternative label: TIF51B
gene: ANB1
locus tag: YJR047C
gene synonym: HYP1; TIF51B
so part of: sequence
location: complement(<524908..>525381)
location: region:524908-525381:-1
so has part: feature:524908-525381:-1:exon
subclass of: SO_0000010

853506
type: Gene
SIO_000068: ncbigene

position:524908:-1
position: 524908
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:525381:-1
position: 525381
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:524908-525381:-1:exon

YJR047C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: HYP1
alternative label: TIF51B
gene: ANB1
locus tag: YJR047C
gene synonym: HYP1; TIF51B
product: translation elongation factor eIF-5A
transcript id: NM_001181705.3
SIO_010081: YJR047C
subclass of: SO_0000673
so part of: YJR047C
location: complement(<524908..>525381)
location: region:524908-525381:-1
so has part: feature:524908-525381:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:524908-525381:-1:exon

YJR047C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: HYP1
alternative label: TIF51B
gene: ANB1
locus tag: YJR047C
gene synonym: HYP1; TIF51B
experiment: EXISTENCE:direct assay:GO:0022626 cytosolic ribosome [PMID:27196944]
experiment: EXISTENCE:genetic interaction:GO:0006452 translational frameshifting [PMID:19424157]
experiment: EXISTENCE:genetic interaction:GO:0045901 positive regulation of translational elongation [PMID:19424157]
note: Translation elongation factor eIF-5A; previously thought to function in translation initiation; undergoes an essential hypusination modification; expressed under anaerobic conditions; ANB1 has a paralog, HYP2, that arose from the whole genome duplication; human EIF5A complements the inviability of the yeast hyp2 anb1 double null mutant
codon start: 1
product: translation elongation factor eIF-5A
translation: MSDEEHTFENADAGASATYPMQCSALRKNGFVVIKGRPCKIVDMSTSKTGKHGHAKVHLVTLDIFTGKKLEDLSPSTHNLEVPFVKRSEYQLLDIDDGYLSLMTMDGETKDDVKAPEGELGDSMQAAFDEGKDLMVTIISAMGEEAAISFKEAPRSD
SIO_010081: YJR047C
subclass of: SO_0000673
so part of: YJR047C
location: complement(524908..525381)
location: region:524908-525381:-1
so has part: feature:524908-525381:-1:exon

NP_012581.3
type: Protein
SIO_000068: ncbiprotein

S000003808
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:524908-525381:-1:exon

YJR048W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CYC1
locus tag: YJR048W
so part of: sequence
location: <526335..>526664
location: region:526335-526664:1
so has part: feature:526335-526664:1:exon
subclass of: SO_0000010

853507
type: Gene
SIO_000068: ncbigene

position:526335:1
position: 526335
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:526664:1
position: 526664
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:526335-526664:1:exon

YJR048W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CYC1
locus tag: YJR048W
product: cytochrome c isoform 1
transcript id: NM_001181706.1
SIO_010081: YJR048W
subclass of: SO_0000673
so part of: YJR048W
location: <526335..>526664
location: region:526335-526664:1
so has part: feature:526335-526664:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:526335-526664:1:exon

YJR048W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CYC1
locus tag: YJR048W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005758 mitochondrial intermembrane space [PMID:9866716]
experiment: EXISTENCE:direct assay:GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c [PMID:7851399]
experiment: EXISTENCE:direct assay:GO:0006123 mitochondrial electron transport, cytochrome c to oxygen [PMID:7851399]
experiment: EXISTENCE:direct assay:GO:0009055 electron transfer activity [PMID:18975895|PMID:7851399]
experiment: EXISTENCE:direct assay:GO:1901612 cardiolipin binding [PMID:30182710]
note: Cytochrome c, isoform 1; also known as iso-1-cytochrome c; electron carrier of mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration; CYC1 has a paralog, CYC7, that arose from the whole genome duplication; human homolog CYC1 can complement yeast null mutant; mutations in human CYC1 cause insulin-responsive hyperglycemia
codon start: 1
product: cytochrome c isoform 1
translation: MTEFKAGSAKKGATLFKTRCLQCHTVEKGGPHKVGPNLHGIFGRHSGQAEGYSYTDANIKKNVLWDENNMSEYLTNPKKYIPGTKMAFGGLKKEKDRNDLITYLKKACE
SIO_010081: YJR048W
subclass of: SO_0000673
so part of: YJR048W
location: 526335..526664
location: region:526335-526664:1
so has part: feature:526335-526664:1:exon

NP_012582.1
type: Protein
SIO_000068: ncbiprotein

S000003809
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:526335-526664:1:exon

YJR049C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: UTR1
locus tag: YJR049C
so part of: sequence
location: complement(<526884..>528476)
location: region:526884-528476:-1
so has part: feature:526884-528476:-1:exon
subclass of: SO_0000010

853508
type: Gene
SIO_000068: ncbigene

position:526884:-1
position: 526884
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:528476:-1
position: 528476
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:526884-528476:-1:exon

YJR049C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: UTR1
locus tag: YJR049C
product: NADH/NAD(+) kinase
transcript id: NM_001181707.1
SIO_010081: YJR049C
subclass of: SO_0000673
so part of: YJR049C
location: complement(<526884..>528476)
location: region:526884-528476:-1
so has part: feature:526884-528476:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:526884-528476:-1:exon

YJR049C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: UTR1
locus tag: YJR049C
EC number: 2.7.1.23
experiment: EXISTENCE:direct assay:GO:0003951 NAD+ kinase activity [PMID:11425472]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0006741 NADP biosynthetic process [PMID:11425472|PMID:15978040]
experiment: EXISTENCE:direct assay:GO:0042736 NADH kinase activity [PMID:15978040]
experiment: EXISTENCE:mutant phenotype:GO:0006879 cellular iron ion homeostasis [PMID:8662826]
note: ATP-NADH kinase; phosphorylates both NAD and NADH; active as a hexamer; enhances the activity of ferric reductase (Fre1p); UTR1 has a paralog, YEF1, that arose from the whole genome duplication
codon start: 1
product: NADH/NAD(+) kinase
translation: MKENDMNNGVDKWVNEEDGRNDHHNNNNNLMKKAMMNNEQIDRTQDIDNAKEMLRKISSESSSRRSSLLNKDSSLVNGNANSGGGTSINGTRGSSKSSNTHFQYASTAYGVRMLSKDISNTKVELDVENLMIVTKLNDVSLYFLTRELVEWVLVHFPRVTVYVDSELKNSKKFAAGELCEDSKCRESRIKYWTKDFIREHDVFFDLVVTLGGDGTVLFVSSIFQRHVPPVMSFSLGSLGFLTNFKFEHFREDLPRIMNHKIKTNLRLRLECTIYRRHRPEVDPNTGKKICVVEKLSTHHILNEVTIDRGPSPFLSMLELYGDGSLMTVAQADGLIAATPTGSTAYSLSAGGSLVCPTVNAIALTPICPHALSFRPIILPESINLKVKVSMKSRAPAWAAFDGKDRIELQKGDFITICASPYAFPTVEASPDEFINSISRQLNWNVREQQKSFTHILSQKNQEKYAHEANKVRNQAEPLEVIRDKYSLEADATKENNNGSDDESDDESVNCEACKLKPSSVPKPSQARFSV
SIO_010081: YJR049C
subclass of: SO_0000673
so part of: YJR049C
location: complement(526884..528476)
location: region:526884-528476:-1
so has part: feature:526884-528476:-1:exon

NP_012583.1
type: Protein
SIO_000068: ncbiprotein

S000003810
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:526884-528476:-1:exon

YJR050W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: NTC30
alternative label: UTR3
gene: ISY1
locus tag: YJR050W
gene synonym: NTC30; UTR3
so part of: sequence
location: <528697..>529404
location: region:528697-529404:1
so has part: feature:528697-529404:1:exon
subclass of: SO_0000010

853509
type: Gene
SIO_000068: ncbigene

position:528697:1
position: 528697
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:529404:1
position: 529404
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:528697-529404:1:exon

YJR050W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: NTC30
alternative label: UTR3
gene: ISY1
locus tag: YJR050W
gene synonym: NTC30; UTR3
product: Isy1p
transcript id: NM_001181708.3
SIO_010081: YJR050W
subclass of: SO_0000673
so part of: YJR050W
location: <528697..>529404
location: region:528697-529404:1
so has part: feature:528697-529404:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:528697-529404:1:exon

YJR050W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: NTC30
alternative label: UTR3
gene: ISY1
locus tag: YJR050W
gene synonym: NTC30; UTR3
experiment: EXISTENCE:curator inference:GO:0000386 second spliceosomal transesterification activity [PMID:10094305]
experiment: EXISTENCE:direct assay:GO:0000974 Prp19 complex [PMID:11018040]
experiment: EXISTENCE:direct assay:GO:0071006 U2-type catalytic step 1 spliceosome [PMID:10094305|PMID:11018040]
experiment: EXISTENCE:direct assay:GO:0071007 U2-type catalytic step 2 spliceosome [PMID:10094305]
experiment: EXISTENCE:direct assay:GO:0071014 post-mRNA release spliceosomal complex [PMID:10094305]
experiment: EXISTENCE:direct assay:GO:0071020 post-spliceosomal complex [PMID:10094305]
experiment: EXISTENCE:genetic interaction:GO:0000384 first spliceosomal transesterification activity [PMID:16103217]
experiment: EXISTENCE:mutant phenotype:GO:0000350 generation of catalytic spliceosome for second transesterification step [PMID:10094305]
experiment: EXISTENCE:mutant phenotype:GO:0000389 mRNA 3'-splice site recognition [PMID:16103217]
note: Member of the NineTeen Complex (NTC); NTC contains Prp19p and stabilizes U6 snRNA in catalytic forms of spliceosome containing U2, U5, and U6 snRNAs; interacts with Prp16p to modulate splicing fidelity; isy1 syf2 cells have defective spindles
codon start: 1
product: Isy1p
translation: MSRNVDKANSVLVRFQEQQAESAGGYKDYSRYQRPRNVSKVKSIKEANEWKRQVSKEIKQKSTRIYDPSLNEMQIAELNDELNNLFKEWKRWQWHIDHTLMEKKTKRKRLEDSHVLMNSGKLINGKRYFGRALELPEVKEWLKQSQRQNDGGSINTKCIPKDRNDFYYHGKVTAALTEFEANWTSILKAHYNVPVNEDEEEMSRQTQEIHVPTLADMEHWLVQRRKKKLMDELNL
SIO_010081: YJR050W
subclass of: SO_0000673
so part of: YJR050W
location: 528697..529404
location: region:528697-529404:1
so has part: feature:528697-529404:1:exon

NP_012584.3
type: Protein
SIO_000068: ncbiprotein

S000003811
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:528697-529404:1:exon

YJR051W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: OSM1
locus tag: YJR051W
so part of: sequence
location: <529861..>531366
location: region:529861-531366:1
so has part: feature:529861-531366:1:exon
subclass of: SO_0000010

853510
type: Gene
SIO_000068: ncbigene

position:529861:1
position: 529861
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:531366:1
position: 531366
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:529861-531366:1:exon

YJR051W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: OSM1
locus tag: YJR051W
product: fumarate reductase
transcript id: NM_001181709.1
SIO_010081: YJR051W
subclass of: SO_0000673
so part of: YJR051W
location: <529861..>531366
location: region:529861-531366:1
so has part: feature:529861-531366:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:529861-531366:1:exon

YJR051W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: OSM1
locus tag: YJR051W
EC number: 1.3.1.6
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:25378625|PMID:9587404|PMID:16823961|PMID:24769239|PM ID:14576278]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:25378625]
experiment: EXISTENCE:direct assay:GO:0016156 fumarate reductase (NADH) activity [PMID:9587404]
experiment: EXISTENCE:mutant phenotype:GO:0034975 protein folding in endoplasmic reticulum [PMID:25378625]
experiment: EXISTENCE:mutant phenotype:GO:0046443 FAD metabolic process [PMID:17345583]
note: Fumarate reductase, catalyzes the reduction of fumarate to succinate; required for the reoxidation of intracellular NADH under anaerobic conditions; acts as electron acceptor in mitochondrial intermembrane space; has two translation start sites, one at the annotated start codon which produces an ER-targeted form required for anaerobic growth, and one at codon 32 which produces a mitochondrially-targeted form; OSM1 has a paralog, FRD1, that arose from the whole genome duplication
codon start: 1
product: fumarate reductase
translation: MIRSVRRVFIYVSIFVLIIVLKRTLSGTDQTSMKQPVVVIGSGLAGLTTSNRLISKYRIPVVLLDKAASIGGNSIKASSGINGAHTDTQQNLKVMDTPELFLKDTLHSAKGRGVPSLMDKLTKESKSAIRWLQTEFDLKLDLLAQLGGHSVPRTHRSSGKLPPGFEIVQALSKKLKDISSKDSNLVQIMLNSEVVDIELDNQGHVTGVVYMDENGNRKIMKSHHVVFCSGGFGYSKEMLKEYSPNLIHLPTTNGKQTTGDGQKILSKLGAELIDMDQVQVHPTGFIDPNDRENNWKFLAAEALRGLGGILLHPTTGRRFTNELSTRDTVTMEIQSKCPKNDNRALLVMSDKVYENYTNNINFYMSKNLIKKVSINDLIRQYDLQTTASELVTELKSYSDVNTKDTFDRPLIINAFDKDISTESTVYVGEVTPVVHFTMGGVKINEKSQVIKKNSESVLSNGIFAAGEVSGGVHGANRLGGSSLLECVVFGKTAADNIAKLY
SIO_010081: YJR051W
subclass of: SO_0000673
so part of: YJR051W
location: 529861..531366
location: region:529861-531366:1
so has part: feature:529861-531366:1:exon

NP_012585.1
type: Protein
SIO_000068: ncbiprotein

S000003812
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:529861-531366:1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(531516..531675)
location: region:531516-531675:-1
so has part: feature:531516-531675:-1:region

S000007032
type: SGD
SIO_000068: sgd

position:531516:-1
position: 531516
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:531675:-1
position: 531675
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:531516-531675:-1:region

YNCJ0024W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SUF23
locus tag: YNCJ0024W
so part of: sequence
location: 531828..531898
location: region:531828-531898:1
so has part: feature:531828-531898:1:exon
subclass of: SO_0000663

853511
type: Gene
SIO_000068: ncbigene

position:531828:1
position: 531828
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:531898:1
position: 531898
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:531828-531898:1:exon

YNCJ0024W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
gene: SUF23
locus tag: YNCJ0024W
product: tRNA-Gly
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
experiment: EXISTENCE:direct assay:GO:0030371 translation repressor activity [PMID:27609601]
experiment: EXISTENCE:direct assay:GO:0043022 ribosome binding [PMID:27609601]
experiment: EXISTENCE:direct assay:GO:0043555 regulation of translation in response to stress [PMID:27609601]
note: Glycine tRNA (tRNA-Gly); can mutate to suppress +1 frameshift mutations
SIO_010081: YNCJ0024W
subclass of: SO_0000673
so part of: YNCJ0024W
location: 531828..531898
location: region:531828-531898:1
so has part: feature:531828-531898:1:exon

S000006584
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:531828-531898:1:exon

YJR052W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RAD7
locus tag: YJR052W
so part of: sequence
location: <532062..>533759
location: region:532062-533759:1
so has part: feature:532062-533759:1:exon
subclass of: SO_0000010

853512
type: Gene
SIO_000068: ncbigene

position:532062:1
position: 532062
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:533759:1
position: 533759
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:532062-533759:1:exon

YJR052W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RAD7
locus tag: YJR052W
product: UV-damaged DNA-binding protein RAD7
transcript id: NM_001181710.1
SIO_010081: YJR052W
subclass of: SO_0000673
so part of: YJR052W
location: <532062..>533759
location: region:532062-533759:1
so has part: feature:532062-533759:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:532062-533759:1:exon

YJR052W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RAD7
locus tag: YJR052W
experiment: EXISTENCE:direct assay:GO:0000113 nucleotide-excision repair factor 4 complex [PMID:9497356]
experiment: EXISTENCE:direct assay:GO:0000715 nucleotide-excision repair, DNA damage recognition [PMID:15177043]
experiment: EXISTENCE:direct assay:GO:0003684 damaged DNA binding [PMID:9497356]
experiment: EXISTENCE:direct assay:GO:0004842 ubiquitin-protein transferase activity [PMID:16675952]
experiment: EXISTENCE:direct assay:GO:0008094 ATP-dependent activity, acting on DNA [PMID:9497356]
experiment: EXISTENCE:direct assay:GO:0008104 protein localization [PMID:15226437]
experiment: EXISTENCE:direct assay:GO:0031463 Cul3-RING ubiquitin ligase complex [PMID:16675952]
experiment: EXISTENCE:mutant phenotype:GO:0000715 nucleotide-excision repair, DNA damage recognition [PMID:15177043]
experiment: EXISTENCE:mutant phenotype:GO:0006511 ubiquitin-dependent protein catabolic process [PMID:16675952]
note: Nucleotide excision repair (NER) protein; binds damaged DNA during NER; binds DNA in an ATP-dependent manner (with Rad16p) during NER; required for repair of non-transcribed chromatin; subunit of Nucleotide Excision Repair Factor 4 (NEF4) and the Elongin-Cullin-Socs (ECS) ligase complex
codon start: 1
product: UV-damaged DNA-binding protein RAD7
translation: MYRSRNRPKRGGENEVKGPNSALTQFLREEGISAENIKQKWYQRQSKKQEDATDEKKGKAEDDSFTAEISRVVEDEEIDEIGTGSGTETERAQVSYDARMKLVPADSDEEEYETSHISDTPVSLSSANDRESLTKKRQNTAKIIQNRRRKRKRAADLLDRRVNKVSSLQSLCITKISENISKWQKEADESSKLVFNKLRDVLGGVSTANLNNLAKALSKNRALNDHTLQLFLKTDLKRLTFSDCSKISFDGYKTLAIFSPHLTELSLQMCGQLNHESLLYIAEKLPNLKSLNLDGPFLINEDTWEKFFVIMKGRLEEFHISNTHRFTDKSLSNLLINCGSTLVSLGLSRLDSISNYALLPQYLVNDEFHSLCIEYPFNEEDVNDEIIINLLGQIGRTLRKLVLNGCIDLTDSMIINGLTAFIPEKCPLEVLSLEESDQITTDSLSYFFSKVELNNLIECSFRRCLQLGDMAIIELLLNGARDSLRSLNLNSLKELTKEAFVALACPNLTYLDLGFVRCVDDSVIQMLGEQNPNLTVIDVFGDNLVTEKATMRPGLTLIGRQSDSI
SIO_010081: YJR052W
subclass of: SO_0000673
so part of: YJR052W
location: 532062..533759
location: region:532062-533759:1
so has part: feature:532062-533759:1:exon

NP_012586.1
type: Protein
SIO_000068: ncbiprotein

S000003813
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:532062-533759:1:exon

YJR053W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: IBD1
gene: BFA1
locus tag: YJR053W
gene synonym: IBD1
so part of: sequence
location: <534027..>535751
location: region:534027-535751:1
so has part: feature:534027-535751:1:exon
subclass of: SO_0000010

853513
type: Gene
SIO_000068: ncbigene

position:534027:1
position: 534027
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:535751:1
position: 535751
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:534027-535751:1:exon

YJR053W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: IBD1
gene: BFA1
locus tag: YJR053W
gene synonym: IBD1
product: Bfa1p
transcript id: NM_001181711.3
SIO_010081: YJR053W
subclass of: SO_0000673
so part of: YJR053W
location: <534027..>535751
location: region:534027-535751:1
so has part: feature:534027-535751:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:534027-535751:1:exon

YJR053W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: IBD1
gene: BFA1
locus tag: YJR053W
gene synonym: IBD1
experiment: EXISTENCE:direct assay:GO:0005092 GDP-dissociation inhibitor activity [PMID:19948498]
experiment: EXISTENCE:direct assay:GO:0005096 GTPase activator activity [PMID:12048186|PMID:16682821|PMID:18667533]
experiment: EXISTENCE:direct assay:GO:0005816 spindle pole body [PMID:10220406|PMID:15147270]
experiment: EXISTENCE:direct assay:GO:1990334 Bfa1-Bub2 complex [PMID:25658911]
experiment: EXISTENCE:mutant phenotype:GO:0001100 negative regulation of exit from mitosis [PMID:15147270|PMID:18667533]
experiment: EXISTENCE:mutant phenotype:GO:0031578 mitotic spindle orientation checkpoint signaling [PMID:16039591]
experiment: EXISTENCE:physical interaction:GO:1990334 Bfa1-Bub2 complex [PMID:11493673]
note: Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p; contributes to GAP activity, inactivating Tem1 by stimulating GTP hydrolysis following damage or misalignment of the mitotic spindle; functions as a guanine-nucleotide exchange inhibitor (GDI) for Tem1p; involved in multiple cell cycle checkpoint pathways that control mitotic exit; required when telomeres are damaged, but not for all types of chromosomal DNA damage; phosphorylated by the Polo-like kinase Cdc5p
codon start: 1
product: Bfa1p
translation: MSIRPLTLNGLDEPETSFEELNTTLPRFQSHETLTLEENVPPLSTSTYIPPPSSVGTSDTGTVFSNSTSAFWSNKQADDDQDMEVDQDDEFLNDFQEFQNKKDDFDDAIKTNFHLRNGCRTGPFKNDIFAEEFDRKLSLEDKPRLKQPRSMMELKPKRKLSNSVTSRNLRSGNSVRFKKSMPNLALVNPAIREEEEDEEREREDQREFNYKIDNDTQDTILAKFSSDDEGDFLTGFEELEGEAIDETISSNDKESADHPRFLKKSSSSLPLKISPAQYDIVKHDELLTPGLHRRQRDWNTQQELDSFKEKRSVRHCSNQNVQLNGPAKIKTIKQQIDHNTPMKKGSMIYNPKTMKWEGNENVLSKFSDVDTANRKALLIKNKLQRDADSKKQKYSDLQHARATSRNQKVIGNMILDEQNLRWVSVSEEEADPFAGIPEINLPPVGKSMKKRSSSPFLRSKSQVNTPFVSNDNDGVYQSTAAQARLRKYHSMRTLNGTTETPEISSTFHLSSRALEKFYHEENRWCKKLASWFIPRDETIISVDEETIMDESTVNSKRKSYMYEIRNMVINSTKD
SIO_010081: YJR053W
subclass of: SO_0000673
so part of: YJR053W
location: 534027..535751
location: region:534027-535751:1
so has part: feature:534027-535751:1:exon

NP_012587.3
type: Protein
SIO_000068: ncbiprotein

S000003814
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:534027-535751:1:exon

YJR054W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: KCH1
locus tag: YJR054W
so part of: sequence
location: <536056..>537549
location: region:536056-537549:1
so has part: feature:536056-537549:1:exon
subclass of: SO_0000010

853514
type: Gene
SIO_000068: ncbigene

position:536056:1
position: 536056
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:537549:1
position: 537549
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:536056-537549:1:exon

YJR054W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: KCH1
locus tag: YJR054W
product: Kch1p
transcript id: NM_001181712.1
SIO_010081: YJR054W
subclass of: SO_0000673
so part of: YJR054W
location: <536056..>537549
location: region:536056-537549:1
so has part: feature:536056-537549:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:536056-537549:1:exon

YJR054W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: KCH1
locus tag: YJR054W
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:23204190]
experiment: EXISTENCE:direct assay:GO:0005937 mating projection [PMID:23204190]
experiment: EXISTENCE:direct assay:GO:0015079 potassium ion transmembrane transporter activity [PMID:23204190]
experiment: EXISTENCE:direct assay:GO:0071805 potassium ion transmembrane transport [PMID:23204190]
note: Potassium transporter that mediates K+ influx; activates high-affinity Ca2+ influx system (HACS) during mating pheromone response; expression up-regulated in response to alpha factor; localized to sites of polarized growth; member of a fungal-specific gene family; potential Cdc28p substrate; KCH1 has a paralog, PRM6, that arose from the whole genome duplication
codon start: 1
product: Kch1p
translation: MFNHDWKYSINSKTFADLNIELFRNHKFKTVLNYIIGVVGWNGLKLALFVSDIYTCIKLLAFNSWSNNIIKPYLPFKISKWLFSGCILASIVLLIWEAIAGMRIYKTGNISLTYVNNFSRNLNSVLNYSKFCVYNMIERKGFRQKMTFFTFFQLKDCIRLIFTDTPRQVINGLTLWSVLVTVNKNEDLGDLESFTGLINKIKNIGQTNHEEAVILSLMLFSFIIWALFVFKFLLAVICSIFVYYKIINDQEYSGLREYICVTVSENVDELVERQRKKENDDTIYKTGLLESQTFDDFKEVENKIETSFNDTSYASNNDSMIELIERRPEYKSQDVCGPIPTMKKTETMESFVDNGNPQYTTRFSAILDSPYINSYESNDIKKAKIQSRSVNTPKYEDLSSSDIFNKIHSAGQLKSTTSMEFHGPLDSMPNTTNNIRNFNSNSSRPRPPPLQTKSSINSKADSNDNGRIYTPMKAYFREPDLPRKGLLEDEDRTYNYT
SIO_010081: YJR054W
subclass of: SO_0000673
so part of: YJR054W
location: 536056..537549
location: region:536056-537549:1
so has part: feature:536056-537549:1:exon

NP_012588.1
type: Protein
SIO_000068: ncbiprotein

S000003815
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:536056-537549:1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(537741..538041)
location: region:537741-538041:-1
so has part: feature:537741-538041:-1:region

S000007033
type: SGD
SIO_000068: sgd

position:537741:-1
position: 537741
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:538041:-1
position: 538041
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:537741-538041:-1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 538103..538434
location: region:538103-538434:1
so has part: feature:538103-538434:1:region

S000007044
type: SGD
SIO_000068: sgd

position:538103:1
position: 538103
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:538434:1
position: 538434
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:538103-538434:1:region

YNCJ0025W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HSX1
locus tag: YNCJ0025W
so part of: sequence
location: 538555..538626
location: region:538555-538626:1
so has part: feature:538555-538626:1:exon
subclass of: SO_0000663

853515
type: Gene
SIO_000068: ncbigene

position:538555:1
position: 538555
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:538626:1
position: 538626
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:538555-538626:1:exon

YNCJ0025W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
gene: HSX1
locus tag: YNCJ0025W
product: tRNA-Arg
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Arginine tRNA (tRNA-Arg), predicted by tRNAscan-SE analysis; low abundance tRNA required for growth on nonfermentable carbon sources at high temperatures, for synthesis of heat shock protein Ssc1p, and for Ty1 retrotransposition through the regulation of translational frameshifting
SIO_010081: YNCJ0025W
subclass of: SO_0000673
so part of: YNCJ0025W
location: 538555..538626
location: region:538555-538626:1
so has part: feature:538555-538626:1:exon

S000006707
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:538555-538626:1:exon

YJR055W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HIT1
locus tag: YJR055W
so part of: sequence
location: <538772..>539266
location: region:538772-539266:1
so has part: feature:538772-539266:1:exon
subclass of: SO_0000010

853516
type: Gene
SIO_000068: ncbigene

position:538772:1
position: 538772
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:539266:1
position: 539266
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:538772-539266:1:exon

YJR055W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HIT1
locus tag: YJR055W
product: Hit1p
transcript id: NM_001181713.1
SIO_010081: YJR055W
subclass of: SO_0000673
so part of: YJR055W
location: <538772..>539266
location: region:538772-539266:1
so has part: feature:538772-539266:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:538772-539266:1:exon

YJR055W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: HIT1
locus tag: YJR055W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:25170085]
experiment: EXISTENCE:mutant phenotype:GO:0000492 box C/D snoRNP assembly [PMID:25170085]
note: Protein involved in C/D snoRNP assembly; regulates abundance of Rsa1p; required for growth at high temperature; mutations in human homolog ZNHIT3 cause PEHO syndrome
codon start: 1
product: Hit1p
translation: MVSSAVKCGICRGVDGKYKCPKCGVRYCSLKCYKDAAKHVHKESEQPRAGTEANVEVVNNDKIINSSLAMNKTLKTKAFDDIYQNSAELQELLKYNTVKFHLAKVYRILSSTVNDGSSGKMNSDLQKELAVNYLNTLRYGGIHYNEAIEEFCQILLDKLNAVKK
SIO_010081: YJR055W
subclass of: SO_0000673
so part of: YJR055W
location: 538772..539266
location: region:538772-539266:1
so has part: feature:538772-539266:1:exon

NP_012589.1
type: Protein
SIO_000068: ncbiprotein

S000003816
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:538772-539266:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1018; Autonomously Replicating Sequence
so part of: sequence
location: 540546..540780
location: region:540546-540780:1
so has part: feature:540546-540780:1:region

S000028455
type: SGD
SIO_000068: sgd

position:540546:1
position: 540546
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:540780:1
position: 540780
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:540546-540780:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 540766..541087
location: region:540766-541087:1
so has part: feature:540766-541087:1:region

S000007045
type: SGD
SIO_000068: sgd

position:540766:1
position: 540766
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:541087:1
position: 541087
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:540766-541087:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(541095..541427)
location: region:541095-541427:-1
so has part: feature:541095-541427:-1:region

S000007034
type: SGD
SIO_000068: sgd

position:541095:-1
position: 541095
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:541427:-1
position: 541427
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:541095-541427:-1:region

YNCJ0026W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCJ0026W
so part of: sequence
location: 541508..541579
location: region:541508-541579:1
so has part: feature:541508-541579:1:exon
subclass of: SO_0000663

853517
type: Gene
SIO_000068: ncbigene

position:541508:1
position: 541508
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:541579:1
position: 541579
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:541508-541579:1:exon

YNCJ0026W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCJ0026W
product: tRNA-Asp
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Aspartate tRNA (tRNA-Asp), predicted by tRNAscan-SE analysis
SIO_010081: YNCJ0026W
subclass of: SO_0000673
so part of: YNCJ0026W
location: 541508..541579
location: region:541508-541579:1
so has part: feature:541508-541579:1:exon

S000006539
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:541508-541579:1:exon

YJR056C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJR056C
so part of: sequence
location: complement(<541792..>542502)
location: region:541792-542502:-1
so has part: feature:541792-542502:-1:exon
subclass of: SO_0000010

853518
type: Gene
SIO_000068: ncbigene

position:541792:-1
position: 541792
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:542502:-1
position: 542502
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:541792-542502:-1:exon

YJR056C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJR056C
product: uncharacterized protein
transcript id: NM_001181714.3
SIO_010081: YJR056C
subclass of: SO_0000673
so part of: YJR056C
location: complement(<541792..>542502)
location: region:541792-542502:-1
so has part: feature:541792-542502:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:541792-542502:-1:exon

YJR056C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJR056C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095|PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095|PMID:22842922]
note: hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus; relative distribution to the nucleus increases upon DNA replication stress
codon start: 1
product: uncharacterized protein
translation: MEQMHSLESSLPPEQPPTKQAIESLNLELSQEFKLAANAVTRLYRVANEKNSLTKHQGYLTCLDDILCALDSNVTADELRAWCYKRRNDILSNSQDKSLNPVKERERKLNKFSENQHRENEAHKEPFEKDSAVKYNFSFNESNGDLSNINENIAPKFRLSMPPLSVEHPPRNASRIKSWKARTINHGRGDTRNLNDITGLGHERERDRENTHYEKKPKLDSDSEVDIRSFRQDMDL
SIO_010081: YJR056C
subclass of: SO_0000673
so part of: YJR056C
location: complement(541792..542502)
location: region:541792-542502:-1
so has part: feature:541792-542502:-1:exon

NP_012590.3
type: Protein
SIO_000068: ncbiprotein

S000003817
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:541792-542502:-1:exon

YNCJ0027C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SUP4
locus tag: YNCJ0027C
so part of: sequence
location: complement(542956..543044)
location: region:542956-543044:-1
so has part: feature:542956-543044:-1:exon
subclass of: SO_0000663

853519
type: Gene
SIO_000068: ncbigene

position:542956:-1
position: 542956
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:543044:-1
position: 543044
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:542956-543044:-1:exon

YNCJ0027C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
gene: SUP4
locus tag: YNCJ0027C
product: tRNA-Tyr
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Tyrosine tRNA (tRNA-Tyr), predicted by tRNAscan-SE analysis; can mutate to suppress ochre nonsense mutations
SIO_010081: YNCJ0027C
subclass of: SO_0000673
so part of: YNCJ0027C
location: complement(join(542956..542991,543006..543044))
location: region:542956-543044:-1
so has part: feature:543006-543044:-1:exon
so has part: feature:542956-542991:-1:exon

S000006782
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:543006-543044:-1:exon

position:543006:-1
position: 543006
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:542956-542991:-1:exon

position:542991:-1
position: 542991
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 543448..543770
location: region:543448-543770:1
so has part: feature:543448-543770:1:region

S000007046
type: SGD
SIO_000068: sgd

position:543448:1
position: 543448
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:543770:1
position: 543770
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:543448-543770:1:region

YJR057W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CDC8
locus tag: YJR057W
so part of: sequence
location: <544062..>544712
location: region:544062-544712:1
so has part: feature:544062-544712:1:exon
subclass of: SO_0000010

853520
type: Gene
SIO_000068: ncbigene

position:544062:1
position: 544062
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:544712:1
position: 544712
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:544062-544712:1:exon

YJR057W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CDC8
locus tag: YJR057W
product: bifunctional thymidylate/uridylate kinase
transcript id: NM_001181715.1
SIO_010081: YJR057W
subclass of: SO_0000673
so part of: YJR057W
location: <544062..>544712
location: region:544062-544712:1
so has part: feature:544062-544712:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:544062-544712:1:exon

YJR057W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CDC8
locus tag: YJR057W
EC number: 2.7.4.9
experiment: EXISTENCE:direct assay:GO:0004550 nucleoside diphosphate kinase activity [PMID:19540237]
experiment: EXISTENCE:direct assay:GO:0004798 thymidylate kinase activity [PMID:6088527|PMID:6094555|PMID:19540237]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:6094555]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:6094555]
experiment: EXISTENCE:direct assay:GO:0006227 dUDP biosynthetic process [PMID:6094555]
experiment: EXISTENCE:direct assay:GO:0006233 dTDP biosynthetic process [PMID:6094555|PMID:6088527|PMID:19540237]
experiment: EXISTENCE:direct assay:GO:0006235 dTTP biosynthetic process [PMID:19540237]
experiment: EXISTENCE:direct assay:GO:0009041 uridylate kinase activity [PMID:6094555]
experiment: EXISTENCE:genetic interaction:GO:0004798 thymidylate kinase activity [PMID:6091111]
experiment: EXISTENCE:genetic interaction:GO:0006233 dTDP biosynthetic process [PMID:6091111]
experiment: EXISTENCE:mutant phenotype:GO:0004550 nucleoside diphosphate kinase activity [PMID:19540237]
experiment: EXISTENCE:mutant phenotype:GO:0004798 thymidylate kinase activity [PMID:19540237|PMID:6088527|PMID:6091111]
experiment: EXISTENCE:mutant phenotype:GO:0006233 dTDP biosynthetic process [PMID:19540237|PMID:6088527|PMID:6091111]
experiment: EXISTENCE:mutant phenotype:GO:0006235 dTTP biosynthetic process [PMID:19540237]
note: Nucleoside monophosphate and nucleoside diphosphate kinase; functions in the de novo biosynthesis of pyrimidine deoxyribonucleotides; thymidylate/uridylate kinase that converts nucleoside monophosphates, dTMP and dUMP to nucleoside diphosphates, dTDP and dUDP; nucleoside diphosphate kinase that converts nucleoside diphosphates, dTDP and dUDP to dTTP and dUTP; essential for mitotic and meiotic DNA replication; homologous to S. pombe tmp1; human homolog DTYMK can complement the cdc8 null mutant
codon start: 1
product: bifunctional thymidylate/uridylate kinase
translation: MMGRGKLILIEGLDRTGKTTQCNILYKKLQPNCKLLKFPERSTRIGGLINEYLTDDSFQLSDQAIHLLFSANRWEIVDKIKKDLLEGKNIVMDRYVYSGVAYSAAKGTNGMDLDWCLQPDVGLLKPDLTLFLSTQDVDNNAEKSGFGDERYETVKFQEKVKQTFMKLLDKEIRKGDESITIVDVTNKGIQEVEALIWQIVEPVLSTHIDHDKFSFF
SIO_010081: YJR057W
subclass of: SO_0000673
so part of: YJR057W
location: 544062..544712
location: region:544062-544712:1
so has part: feature:544062-544712:1:exon

NP_012591.1
type: Protein
SIO_000068: ncbiprotein

S000003818
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:544062-544712:1:exon

YJR058C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YAP17
gene: APS2
locus tag: YJR058C
gene synonym: YAP17
so part of: sequence
location: complement(<544732..>545175)
location: region:544732-545175:-1
so has part: feature:544732-545175:-1:exon
subclass of: SO_0000010

853521
type: Gene
SIO_000068: ncbigene

position:544732:-1
position: 544732
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:545175:-1
position: 545175
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:544732-545175:-1:exon

YJR058C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YAP17
gene: APS2
locus tag: YJR058C
gene synonym: YAP17
product: Aps2p
transcript id: NM_001181716.1
SIO_010081: YJR058C
subclass of: SO_0000673
so part of: YJR058C
location: complement(<544732..>545175)
location: region:544732-545175:-1
so has part: feature:544732-545175:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:544732-545175:-1:exon

YJR058C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YAP17
gene: APS2
locus tag: YJR058C
gene synonym: YAP17
experiment: EXISTENCE:curator inference:GO:0006886 intracellular protein transport [PMID:10564262]
experiment: EXISTENCE:direct assay:GO:0005628 prospore membrane [PMID:24390141]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0030122 AP-2 adaptor complex [PMID:10564262]
experiment: EXISTENCE:direct assay:GO:0030136 clathrin-coated vesicle [PMID:8157009]
experiment: EXISTENCE:physical interaction:GO:0030122 AP-2 adaptor complex [PMID:10564262]
note: Small subunit of the clathrin-associated adaptor complex AP-2; AP-2 is involved in protein sorting at the plasma membrane; related to the sigma subunit of the mammalian plasma membrane clathrin-associated protein (AP-2) complex
codon start: 1
product: Aps2p
translation: MAVQFILCFNKQGVVRLVRWFDVHSSDPQRSQDAIAQIYRLISSRDHKHQSNFVEFSDSTKLIYRRYAGLYFVMGVDLLDDEPIYLCHIHLFVEVLDAFFGNVCELDIVFNFYKVYMIMDEMFIGGEIQEISKDMLLERLSILDRLD
SIO_010081: YJR058C
subclass of: SO_0000673
so part of: YJR058C
location: complement(544732..545175)
location: region:544732-545175:-1
so has part: feature:544732-545175:-1:exon

NP_012592.1
type: Protein
SIO_000068: ncbiprotein

S000003819
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:544732-545175:-1:exon

YJR059W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: STK2
gene: PTK2
locus tag: YJR059W
gene synonym: STK2
so part of: sequence
location: <545787..>548243
location: region:545787-548243:1
so has part: feature:545787-548243:1:exon
subclass of: SO_0000010

853522
type: Gene
SIO_000068: ncbigene

position:545787:1
position: 545787
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:548243:1
position: 548243
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:545787-548243:1:exon

YJR059W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: STK2
gene: PTK2
locus tag: YJR059W
gene synonym: STK2
product: protein kinase PTK2
transcript id: NM_001181717.3
SIO_010081: YJR059W
subclass of: SO_0000673
so part of: YJR059W
location: <545787..>548243
location: region:545787-548243:1
so has part: feature:545787-548243:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:545787-548243:1:exon

YJR059W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: STK2
gene: PTK2
locus tag: YJR059W
gene synonym: STK2
EC number: 2.7.11.1
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:16319894|PMID:16510118]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:12206772]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:12206772]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:16510118]
experiment: EXISTENCE:direct assay:GO:0006468 protein phosphorylation [PMID:16319894]
experiment: EXISTENCE:genetic interaction:GO:0000082 G1/S transition of mitotic cell cycle [PMID:12518319]
experiment: EXISTENCE:mutant phenotype:GO:0000296 spermine transport [PMID:8920934]
experiment: EXISTENCE:mutant phenotype:GO:0006873 cellular ion homeostasis [PMID:11003661]
experiment: EXISTENCE:mutant phenotype:GO:0008361 regulation of cell size [PMID:12089449]
experiment: EXISTENCE:mutant phenotype:GO:0015847 putrescine transport [PMID:9154797]
experiment: EXISTENCE:mutant phenotype:GO:0015848 spermidine transport [PMID:9154797]
note: Serine/threonine protein kinase; involved in regulation of ion transport across plasma membrane; carboxyl terminus is essential for glucose-dependent Pma1p activation via phosphorylation of Pma1p-Ser899; enhances spermine uptake; PTK2 has a paralog, PTK1, that arose from the whole genome duplication
codon start: 1
product: protein kinase PTK2
translation: MAGNGKDKEVDKSPSVSTLKLLGKRLFNSSSHTDNSSLLLSAEQLGNGRSLRKRPTSPSISGSGSGGNSPSSSAGARQRSASLHRRKNNASVGFSNGSVSSHKSSVALQDLIKHNNNPYLNSPSDILGTGTGIASTRDRDRAVLDREKEKERARNKERNTHHAGLPQRSNSMASHHFPNENIVYNPYGISPNHARPDTAFADTLNTNKENDLSFYMHDGNSKIRMLPLPIANPNDFLPEDMKQYSVHLTDNFVFDTDNKPIGSGGSSEVRKVKSSYRQKDVYALKKLNMIYHESPEKFYKRCSKEFIIAKHLSHNVHITNTFYLLKVPTTTYTTRGWGFIMELGVKDLFQLMERTGWKNVPFNEKYCLFKQVAQGIKFCHDNGIAHRDLKPENVLISKEGICKLTDFGISDWYHVIPHDYTSPVKTCQGMIGSPPYTPPEVMYFDAKKHYPEKFQKPYNPLAMDSYALGIMLITMINNIIPFIDSCNTDARFREFEVSYDNFINHQNPHFRDKGCHKPGPGSEYSLARNFKNTDATRIAWRLADPNPATRYTMDDLFNDPFFQQIETCVEPNDDDLVRVPELRKSTSTNDFSENSLDAPHDQEVIHTSNPFLKKETLTSKPRSMLEIAESPSLKQKSKVKDSAKTKTHDVGDEGGNESTKPKQQDKKENLKKDEVKNGDKDKVIEEATTTNVDSILEKPTPTSTKVEDNLSEDDSTMKELKSMLNSTPTTPTHNGPTPLPAKAGTQLDKRMSDLSLKSETPASTKNFSAPNVSSSSNSLRSLGSPSVSSSKKKKVIHHHLDITNSVTNMSSVSAFISR
SIO_010081: YJR059W
subclass of: SO_0000673
so part of: YJR059W
location: 545787..548243
location: region:545787-548243:1
so has part: feature:545787-548243:1:exon

NP_012593.3
type: Protein
SIO_000068: ncbiprotein

S000003820
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:545787-548243:1:exon

YJR060W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CEP1
alternative label: CPF1
gene: CBF1
locus tag: YJR060W
gene synonym: CEP1; CPF1
so part of: sequence
location: <548759..>549814
location: region:548759-549814:1
so has part: feature:548759-549814:1:exon
subclass of: SO_0000010

853523
type: Gene
SIO_000068: ncbigene

position:548759:1
position: 548759
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:549814:1
position: 549814
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:548759-549814:1:exon

YJR060W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CEP1
alternative label: CPF1
gene: CBF1
locus tag: YJR060W
gene synonym: CEP1; CPF1
product: Cbf1p
transcript id: NM_001181718.1
SIO_010081: YJR060W
subclass of: SO_0000673
so part of: YJR060W
location: <548759..>549814
location: region:548759-549814:1
so has part: feature:548759-549814:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:548759-549814:1:exon

YJR060W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CEP1
alternative label: CPF1
gene: CBF1
locus tag: YJR060W
gene synonym: CEP1; CPF1
experiment: EXISTENCE:direct assay:GO:0000775 chromosome, centromeric region [PMID:9407032]
experiment: EXISTENCE:direct assay:GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding [PMID:7891681|PMID:8665859|PMID:9894911]
experiment: EXISTENCE:direct assay:GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific [PMID:15302821]
experiment: EXISTENCE:direct assay:GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific [PMID:7891681]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:24769239|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0006338 chromatin remodeling [PMID:15111622]
experiment: EXISTENCE:direct assay:GO:0019237 centromeric DNA binding [PMID:11222754|PMID:2057354|PMID:2249662|PMID:9407032]
experiment: EXISTENCE:direct assay:GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding [PMID:12820973]
experiment: EXISTENCE:direct assay:GO:0089713 Cbf1-Met4-Met28 complex [PMID:8665859|PMID:9171357]
experiment: EXISTENCE:genetic interaction:GO:0007059 chromosome segregation [PMID:9584087]
experiment: EXISTENCE:mutant phenotype:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:10921921|PMID:22696683|PMID:15302821]
experiment: EXISTENCE:mutant phenotype:GO:0006338 chromatin remodeling [PMID:21131275|PMID:2249662|PMID:7891681]
experiment: EXISTENCE:mutant phenotype:GO:0006357 regulation of transcription by RNA polymerase II [PMID:7891681]
experiment: EXISTENCE:mutant phenotype:GO:0007059 chromosome segregation [PMID:2057354|PMID:2185892|PMID:2188087]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:22696683|PMID:7601277|PMID:7891681|PMID:17351075|PMI D:20935143]
experiment: EXISTENCE:mutant phenotype:GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding [PMID:20935143]
experiment: EXISTENCE:mutant phenotype:GO:0098781 ncRNA transcription [PMID:31391265]
experiment: EXISTENCE:physical interaction:GO:0000776 kinetochore [PMID:11070082]
experiment: EXISTENCE:physical interaction:GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding [PMID:8665859]
note: Basic helix-loop-helix (bHLH) protein; forms homodimer to bind E-box consensus sequence CACGTG present at MET gene promoters and centromere DNA element I (CDEI); affects nucleosome positioning at this motif; associates with other transcription factors such as Met4p and Isw1p to mediate transcriptional activation or repression; associates with kinetochore proteins, required for chromosome segregation; protein abundance increases in response to DNA replication stress
codon start: 1
product: Cbf1p
translation: MNSLANNNKLSTEDEEIHSARKRGYNEEQNYSEARKKQRDQGLLSQESNDGNIDSALLSEGATLKGTQSQYESGLTSNKDEKGSDDEDASVAEAAVAATVNYTDLIQGQEDSSDAHTSNQTNANGEHKDSLNGERAITPSNEGVKPNTSLEGMTSSPMESTQQSKNDMLIPLAEHDRGPEHQQDDEDNDDADIDLKKDISMQPGRRGRKPTTLATTDEWKKQRKDSHKEVERRRRENINTAINVLSDLLPVRESSKAAILACAAEYIQKLKETDEANIEKWTLQKLLSEQNASQLASANEKLQEELGNAYKEIEYMKRVLRKEGIEYEDMHTHKKQENERKSTRSDNPHEA
SIO_010081: YJR060W
subclass of: SO_0000673
so part of: YJR060W
location: 548759..549814
location: region:548759-549814:1
so has part: feature:548759-549814:1:exon

NP_012594.1
type: Protein
SIO_000068: ncbiprotein

S000003821
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:548759-549814:1:exon

YJR061W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MNN14
locus tag: YJR061W
so part of: sequence
location: <550511..>553318
location: region:550511-553318:1
so has part: feature:550511-553318:1:exon
subclass of: SO_0000010

853524
type: Gene
SIO_000068: ncbigene

position:550511:1
position: 550511
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:553318:1
position: 553318
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:550511-553318:1:exon

YJR061W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MNN14
locus tag: YJR061W
product: Mnn14p
transcript id: NM_001181719.1
SIO_010081: YJR061W
subclass of: SO_0000673
so part of: YJR061W
location: <550511..>553318
location: region:550511-553318:1
so has part: feature:550511-553318:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:550511-553318:1:exon

YJR061W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MNN14
locus tag: YJR061W
experiment: EXISTENCE:genetic interaction:GO:0006491 N-glycan processing [PMID:28101612]
note: Protein required for N-glycan mannosylphosphorylation; non-essential gene; transcription repressed by Rm101p; MNN14 has a paralog, MNN4, that arose from the whole genome duplication
codon start: 1
product: Mnn14p
translation: MMLSLRRFSMYVLRSLRLHFKKIIITLLTIQLLFITIFVLGGRSSIIDGNWKSFMALFFKPLAYTNRNNNHASFDLRSKDNVAKLYEKMNFDTSGKWIDTYTLKNNLLTVKMGPEKGQVLDSVDELRYYDNDPRLVWSVLLDHLLESDSNEYAFSWYDWANFDSTNKLIALRHTNISCQFVCEGAFDKNVLEMVESEVQEPLFVTNRNKYDESLWYNRVRKVVDSNSVQQAIHDHCMNNDAYSNGTPFELPFIISEISERLRPEVYDLQAKNHLLYSNFTPLSLTVLDSDKDAYRINLKTTDSSKSNIVQTNLLQNYIKRHRNEMVNGDLIFNHTSMFEKFLHHGSTKKRKLDVEALDKTIYAGEYLELSPSDFQFNAKERIIELETRLRSEGLPSHDTHYLRSLKTSVNTSPALQQKYFAEASDITDATADGHHRDRRFFSIGHNLLNDPQEFEARLNSLIRNFQKFVKANGLISWLSHGTLYGYLYDGLKFPWDVDHDLQMPIKHLHYLSQYFNQSLILEDPREGNGRFLLDVGSAITVGVHGNGENNIDARFIDIDSGIYIDITGLSVSSDAAKQYMSKFVEEESSGESFSALIEDYKFDENDYFDEVDGREGLAKYTIHELMEWVNSHPDDFTDAEKNLVTKTYKKELAISRSDYAEKDLSPKQRYLVNEKYNLYNCRNQHFSSLNIISPLRNTMFSGVSAFVPNRPIATLNNEYKVPAKYGLLSFQGKVYLPEFRYWFSFADMKKFANLQLKEPKITRLESPLNDLKFSDISLLITNILKCGFHSVFASLFNSFDSTVYRLKELEIQYDPSLSEEEKSSLLKTLRRGMSKKIKSPEKDPIIYIYERKLWENVEKLLNASNIYNIASQVEKEKGKEFVERSQQVYERNFDGFRLPDGGNSKTVNDLNSKGLNLFGDNKKTSNNIFGSDQKY
SIO_010081: YJR061W
subclass of: SO_0000673
so part of: YJR061W
location: 550511..553318
location: region:550511-553318:1
so has part: feature:550511-553318:1:exon

NP_012595.1
type: Protein
SIO_000068: ncbiprotein

S000003822
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:550511-553318:1:exon

YJR062C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: DEA1
gene: NTA1
locus tag: YJR062C
gene synonym: DEA1
so part of: sequence
location: complement(<553476..>554849)
location: region:553476-554849:-1
so has part: feature:553476-554849:-1:exon
subclass of: SO_0000010

853525
type: Gene
SIO_000068: ncbigene

position:553476:-1
position: 553476
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:554849:-1
position: 554849
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:553476-554849:-1:exon

YJR062C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: DEA1
gene: NTA1
locus tag: YJR062C
gene synonym: DEA1
product: amidase
transcript id: NM_001181720.3
SIO_010081: YJR062C
subclass of: SO_0000673
so part of: YJR062C
location: complement(<553476..>554849)
location: region:553476-554849:-1
so has part: feature:553476-554849:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:553476-554849:-1:exon

YJR062C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: DEA1
gene: NTA1
locus tag: YJR062C
gene synonym: DEA1
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0008418 protein-N-terminal asparagine amidohydrolase activity [PMID:23218487|PMID:7744855]
experiment: EXISTENCE:direct assay:GO:0070773 protein-N-terminal glutamine amidohydrolase activity [PMID:23218487]
experiment: EXISTENCE:mutant phenotype:GO:0008418 protein-N-terminal asparagine amidohydrolase activity [PMID:7744855]
experiment: EXISTENCE:mutant phenotype:GO:0030163 protein catabolic process [PMID:7744855]
experiment: EXISTENCE:mutant phenotype:GO:0031365 N-terminal protein amino acid modification [PMID:7744855]
experiment: EXISTENCE:mutant phenotype:GO:0070773 protein-N-terminal glutamine amidohydrolase activity [PMID:7744855]
note: Amidase; removes the amide group from N-terminal asparagine and glutamine residues to generate proteins with N-terminal aspartate and glutamate residues that are targets of ubiquitin-mediated degradation
codon start: 1
product: amidase
translation: MLIDAIHGAKMSTKLLVSLKVLVIQLNPQIGQVDQTIKRTWSILDKVTKSATYVKPDIILFPEFALTGYSFHARKDILPYVTKKDEGPSFELAKSISEKFQCYTIIGYPEDDDEQKLYNSALVVNPQGEQIFNYRKTFLYDTEMNWDCEENPEGFQTFPMDFSKCAKLSNEDSYNRDVTLKASIGICMDLSPYKFMAPFNHFEFSSFCVDNNVELILCPMAWLNSTSITDKQTLHNNSLLEAAKNKIAFALKEQGLPLAGSQGIYQLKIGDSQRTPRVPSDDSTSEYKDMDEPDMSNVNYWILRFFPFLYFKSRINWFKNSSLIESILGKTRMPLDHEYYKDGKHKEDTIDLLDSEEVIKDTVLEKTFLGTSLGQPWKFQGKNAILVLANRCGTEDGTTIFAGSSGIYKFNGKKPKGSQDDDESSLDSLNESVELLGNLGKGLEGAILREVQFEVFR
SIO_010081: YJR062C
subclass of: SO_0000673
so part of: YJR062C
location: complement(553476..554849)
location: region:553476-554849:-1
so has part: feature:553476-554849:-1:exon

NP_012596.3
type: Protein
SIO_000068: ncbiprotein

S000003823
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:553476-554849:-1:exon

YJR063W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RRN4
gene: RPA12
locus tag: YJR063W
gene synonym: RRN4
so part of: sequence
location: <555195..>555572
location: region:555195-555572:1
so has part: feature:555195-555572:1:exon
subclass of: SO_0000010

853526
type: Gene
SIO_000068: ncbigene

position:555195:1
position: 555195
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:555572:1
position: 555572
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:555195-555572:1:exon

YJR063W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RRN4
gene: RPA12
locus tag: YJR063W
gene synonym: RRN4
product: DNA-directed RNA polymerase I core subunit RPA12
transcript id: NM_001181721.1
SIO_010081: YJR063W
subclass of: SO_0000673
so part of: YJR063W
location: <555195..>555572
location: region:555195-555572:1
so has part: feature:555195-555572:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:555195-555572:1:exon

YJR063W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RRN4
gene: RPA12
locus tag: YJR063W
gene synonym: RRN4
experiment: EXISTENCE:direct assay:GO:0001054 RNA polymerase I activity [PMID:9837969]
experiment: EXISTENCE:direct assay:GO:0005736 RNA polymerase I complex [PMID:11486042|PMID:9837969|PMID:8417319]
experiment: EXISTENCE:direct assay:GO:0006360 transcription by RNA polymerase I [PMID:9837969]
experiment: EXISTENCE:genetic interaction:GO:0042790 nucleolar large rRNA transcription by RNA polymerase I [PMID:1871118|PMID:9121426]
experiment: EXISTENCE:mutant phenotype:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:27637775]
experiment: EXISTENCE:mutant phenotype:GO:0006363 termination of RNA polymerase I transcription [PMID:15073335|PMID:18413718]
experiment: EXISTENCE:physical interaction:GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding [PMID:27637775]
note: RNA polymerase I subunit A12.2; contains two zinc binding domains, and the N terminal domain is responsible for anchoring to the RNA pol I complex; physically interacts with transcriptional activator Msn4p, to regulate transcription of AYR1, a gene involved in lipid metabolism
codon start: 1
product: DNA-directed RNA polymerase I core subunit RPA12
translation: MSVVGSLIFCLDCGDLLENPNAVLGSNVECSQCKAIYPKSQFSNLKVVTTTADDAFPSSLRAKKSVVKTSLKKNELKDGATIKEKCPQCGNEEMNYHTLQLRSADEGATVFYTCTSCGYKFRTNN
SIO_010081: YJR063W
subclass of: SO_0000673
so part of: YJR063W
location: 555195..555572
location: region:555195-555572:1
so has part: feature:555195-555572:1:exon

NP_012597.1
type: Protein
SIO_000068: ncbiprotein

S000003824
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:555195-555572:1:exon

YJR064W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: TCP5
gene: CCT5
locus tag: YJR064W
gene synonym: TCP5
so part of: sequence
location: <555914..>557602
location: region:555914-557602:1
so has part: feature:555914-557602:1:exon
subclass of: SO_0000010

853527
type: Gene
SIO_000068: ncbigene

position:555914:1
position: 555914
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:557602:1
position: 557602
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:555914-557602:1:exon

YJR064W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: TCP5
gene: CCT5
locus tag: YJR064W
gene synonym: TCP5
product: chaperonin-containing T-complex subunit CCT5
transcript id: NM_001181722.1
SIO_010081: YJR064W
subclass of: SO_0000673
so part of: YJR064W
location: <555914..>557602
location: region:555914-557602:1
so has part: feature:555914-557602:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:555914-557602:1:exon

YJR064W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: TCP5
gene: CCT5
locus tag: YJR064W
gene synonym: TCP5
experiment: EXISTENCE:direct assay:GO:0005832 chaperonin-containing T-complex [PMID:16762366]
experiment: EXISTENCE:direct assay:GO:0006457 protein folding [PMID:16762366]
experiment: EXISTENCE:direct assay:GO:0051082 unfolded protein binding [PMID:16762366]
experiment: EXISTENCE:physical interaction:GO:0005832 chaperonin-containing T-complex [PMID:15704212]
note: Subunit of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo
codon start: 1
product: chaperonin-containing T-complex subunit CCT5
translation: MAARPQQPPMEMPDLSNAIVAQDEMGRPFIIVKDQGNKKRQHGLEAKKSHILAARSVASIIKTSLGPRGLDKILISPDGEITITNDGATILSQMELDNEIAKLLVQLSKSQDDEIGDGTTGVVVLASALLDQALELIQKGIHPIKIANGFDEAAKLAISKLEETCDDISASNDELFRDFLLRAAKTSLGSKIVSKDHDRFAEMAVEAVINVMDKDRKDVDFDLIKMQGRVGGSISDSKLINGVILDKDFSHPQMPKCVLPKEGSDGVKLAILTCPFEPPKPKTKHKLDISSVEEYQKLQTYEQDKFKEMIDDVKKAGADVVICQWGFDDEANHLLLQNDLPAVRWVGGQELEHIAISTNGRIVPRFQDLSKDKLGTCSRIYEQEFGTTKDRMLIIEQSKETKTVTCFVRGSNKMIVDEAERALHDSLCVVRNLVKDSRVVYGGGAAEVTMSLAVSEEADKQRGIDQYAFRGFAQALDTIPMTLAENSGLDPIGTLSTLKSKQLKEKISNIGVDCLGYGSNDMKELFVVDPFIGKKQQILLATQLCRMILKIDNVIISGKDEY
SIO_010081: YJR064W
subclass of: SO_0000673
so part of: YJR064W
location: 555914..557602
location: region:555914-557602:1
so has part: feature:555914-557602:1:exon

NP_012598.1
type: Protein
SIO_000068: ncbiprotein

S000003825
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:555914-557602:1:exon

YJR065C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ACT4
gene: ARP3
locus tag: YJR065C
gene synonym: ACT4
so part of: sequence
location: complement(<557809..>559158)
location: region:557809-559158:-1
so has part: feature:557809-559158:-1:exon
subclass of: SO_0000010

853528
type: Gene
SIO_000068: ncbigene

position:557809:-1
position: 557809
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:559158:-1
position: 559158
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:557809-559158:-1:exon

YJR065C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ACT4
gene: ARP3
locus tag: YJR065C
gene synonym: ACT4
product: actin-related protein 3
transcript id: NM_001181723.3
SIO_010081: YJR065C
subclass of: SO_0000673
so part of: YJR065C
location: complement(<557809..>559158)
location: region:557809-559158:-1
so has part: feature:557809-559158:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:557809-559158:-1:exon

YJR065C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ACT4
gene: ARP3
locus tag: YJR065C
gene synonym: ACT4
experiment: EXISTENCE:direct assay:GO:0005524 ATP binding [PMID:15657399]
experiment: EXISTENCE:direct assay:GO:0005885 Arp2/3 protein complex [PMID:10377407]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:16622836]
experiment: EXISTENCE:direct assay:GO:0030479 actin cortical patch [PMID:9210376]
experiment: EXISTENCE:mutant phenotype:GO:0005524 ATP binding [PMID:15657399]
experiment: EXISTENCE:mutant phenotype:GO:0034314 Arp2/3 complex-mediated actin nucleation [PMID:16862144]
experiment: EXISTENCE:mutant phenotype:GO:0044396 actin cortical patch organization [PMID:15534003|PMID:10377407]
note: Essential component of the Arp2/3 complex; Arp2/3 is a highly conserved actin nucleation center required for the motility and integrity of actin patches; involved in endocytosis and membrane growth and polarity
codon start: 1
product: actin-related protein 3
translation: MSYLNNPAVVMDNGTGLTKLGFAGNDSPSWVFPTAIATAAPSNTKKSSGVGAPSAVSNEASYFGNSTSATNFNGATGGLLSNNLSGKRGTEDLDFYIGNEALVASQGPSYSLSYPIRHGQVENWDHMERFWENSIFKYLRTEPEDHFFLLTEPPLNPPENREQVAEIFFESFNCAGLYIAVQAVLALAASWTSSKVTDRSLTGTVIDSGDGVTHVIPVAEGYVIGSAIKNIPIAGRDITLFIQSLLRERGEADTSLRTAEKIKQEYCYVCPDIVKEFNKFDKDPSKFAQFVVENQEKTRRKVVDIGYERFLAPEIFFNPEIASSDFLTPLPTVVDQTIQACPIDVRKGLYNNIVLSGGSTMFKDFGRRLQRDLKSIVNNRIAQSELLSGTKSTGVDVSVISHRKQRNAVWFGGSLLAQTAEFKGYCHTKKDYEEYGPEIVRNFSLFNMV
SIO_010081: YJR065C
subclass of: SO_0000673
so part of: YJR065C
location: complement(557809..559158)
location: region:557809-559158:-1
so has part: feature:557809-559158:-1:exon

NP_012599.3
type: Protein
SIO_000068: ncbiprotein

S000003826
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:557809-559158:-1:exon

YJR066W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: DRR1
gene: TOR1
locus tag: YJR066W
gene synonym: DRR1
so part of: sequence
location: <559416..>566828
location: region:559416-566828:1
so has part: feature:559416-566828:1:exon
subclass of: SO_0000010

853529
type: Gene
SIO_000068: ncbigene

position:559416:1
position: 559416
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:566828:1
position: 566828
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:559416-566828:1:exon

YJR066W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: DRR1
gene: TOR1
locus tag: YJR066W
gene synonym: DRR1
product: phosphatidylinositol kinase-related protein kinase TOR1
transcript id: NM_001181724.1
SIO_010081: YJR066W
subclass of: SO_0000673
so part of: YJR066W
location: <559416..>566828
location: region:559416-566828:1
so has part: feature:559416-566828:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:559416-566828:1:exon

YJR066W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: DRR1
gene: TOR1
locus tag: YJR066W
gene synonym: DRR1
EC number: 2.7.11.1
experiment: EXISTENCE:direct assay:GO:0000139 Golgi membrane [PMID:12719473]
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:18723607|PMID:19748353|PMID:25046117|PMID:26928762|P MID:12719473]
experiment: EXISTENCE:direct assay:GO:0004674 protein serine/threonine kinase activity [PMID:26582391]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:16900101]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:16900101|PMID:18723607]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:10973982]
experiment: EXISTENCE:direct assay:GO:0010008 endosome membrane [PMID:12719473]
experiment: EXISTENCE:direct assay:GO:0018105 peptidyl-serine phosphorylation [PMID:26582391]
experiment: EXISTENCE:genetic interaction:GO:0010507 negative regulation of autophagy [PMID:9461583]
experiment: EXISTENCE:genetic interaction:GO:0034599 cellular response to oxidative stress [PMID:27922823]
experiment: EXISTENCE:genetic interaction:GO:0034605 cellular response to heat [PMID:27922823]
experiment: EXISTENCE:genetic interaction:GO:1905356 regulation of snRNA pseudouridine synthesis [PMID:27268497]
experiment: EXISTENCE:mutant phenotype:GO:0001558 regulation of cell growth [PMID:12171921]
experiment: EXISTENCE:mutant phenotype:GO:0004672 protein kinase activity [PMID:10329624]
experiment: EXISTENCE:mutant phenotype:GO:0006413 translational initiation [PMID:8741837]
experiment: EXISTENCE:mutant phenotype:GO:0006974 cellular response to DNA damage stimulus [PMID:17698581]
experiment: EXISTENCE:mutant phenotype:GO:0031505 fungal-type cell wall organization [PMID:14736892]
experiment: EXISTENCE:mutant phenotype:GO:0031929 TOR signaling [PMID:12719473|PMID:8186460]
experiment: EXISTENCE:mutant phenotype:GO:0031930 mitochondria-nucleus signaling pathway [PMID:11997479]
experiment: EXISTENCE:mutant phenotype:GO:0034976 response to endoplasmic reticulum stress [PMID:31144305]
experiment: EXISTENCE:mutant phenotype:GO:0042254 ribosome biogenesis [PMID:10198052]
experiment: EXISTENCE:mutant phenotype:GO:0042790 nucleolar large rRNA transcription by RNA polymerase I [PMID:16900101]
experiment: EXISTENCE:mutant phenotype:GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation [PMID:16980405]
experiment: EXISTENCE:mutant phenotype:GO:0051321 meiotic cell cycle [PMID:9096347]
experiment: EXISTENCE:mutant phenotype:GO:0051726 regulation of cell cycle [PMID:8741837]
experiment: EXISTENCE:mutant phenotype:GO:0090153 regulation of sphingolipid biosynthetic process [PMID:23363605]
experiment: EXISTENCE:physical interaction:GO:0031931 TORC1 complex [PMID:12408816]
note: PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that controls growth in response to nutrients by regulating translation, transcription, ribosome biogenesis, nutrient transport and autophagy; involved in meiosis; indole-3-acetic acid, an ATP-competitive inhibitor of TORC1, accumulates upon entry into stationary phase; TOR1 has a paralog, TOR2, that arose from the whole genome duplication
codon start: 1
product: phosphatidylinositol kinase-related protein kinase TOR1
translation: MEPHEEQIWKSKLLKAANNDMDMDRNVPLAPNLNVNMNMKMNASRNGDEFGLTSSRFDGVVIGSNGDVNFKPILEKIFRELTSDYKEERKLASISLFDLLVSLEHELSIEEFQAVSNDINNKILELVHTKKTSTRVGAVLSIDTLISFYAYTERLPNETSRLAGYLRGLIPSNDVEVMRLAAKTLGKLAVPGGTYTSDFVEFEIKSCLEWLTASTEKNSFSSSKPDHAKHAALLIITALAENCPYLLYQYLNSILDNIWRALRDPHLVIRIDASITLAKCLSTLRNRDPQLTSQWVQRLATSCEYGFQVNTLECIHASLLVYKEILFLKDPFLNQVFDQMCLNCIAYENHKAKMIREKIYQIVPLLASFNPQLFAGKYLHQIMDNYLEILTNAPANKIPHLKDDKPQILISIGDIAYEVGPDIAPYVKQILDYIEHDLQTKFKFRKKFENEIFYCIGRLAVPLGPVLGKLLNRNILDLMFKCPLSDYMQETFQILTERIPSLGPKINDELLNLVCSTLSGTPFIQPGSPMEIPSFSRERAREWRNKNILQKTGESNDDNNDIKIIIQAFRMLKNIKSRFSLVEFVRIVALSYIEHTDPRVRKLAALTSCEIYVKDNICKQTSLHSLNTVSEVLSKLLAITIADPLQDIRLEVLKNLNPCFDPQLAQPDNLRLLFTALHDESFNIQSVAMELVGRLSSVNPAYVIPSIRKILLELLTKLKFSTSSREKEETASLLCTLIRSSKDVAKPYIEPLLNVLLPKFQDTSSTVASTALRTIGELSVVGGEDMKIYLKDLFPLIIKTFQDQSNSFKREAALKALGQLAASSGYVIDPLLDYPELLGILVNILKTENSQNIRRQTVTLIGILGAIDPYRQKEREVTSTTDISTEQNAPPIDIALLMQGMSPSNDEYYTTVVIHCLLKILKDPSLSSYHTAVIQAIMHIFQTLGLKCVSFLDQIIPTILDVMRTCSQSLLEFYFQQLCSLIIIVRQHIRPHVDSIFQAIKDFSSVAKLQITLVSVIEAISKALEGEFKRLVPLTLTLFLVILENDKSSDKVLSRRVLRLLESFGPNLEGYSHLITPKIVQMAEFTSGNLQRSAIITIGKLAKDVDLFEMSSRIVHSLLRVLSSTTSDELSKVIMNTLSLLLIQMGTSFAIFIPVINEVLMKKHIQHTIYDDLTNRILNNDVLPTKILEANTTDYKPAEQMEAADAGVAKLPINQSVLKSAWNSSQQRTKEDWQEWSKRLSIQLLKESPSHALRACSNLASMYYPLAKELFNTAFACVWTELYSQYQEDLIGSLCIALSSPLNPPEIHQTLLNLVEFMEHDDKALPIPTQSLGEYAERCHAYAKALHYKEIKFIKEPENSTIESLISINNQLNQTDAAIGILKHAQQHHSLQLKETWFEKLERWEDALHAYNEREKAGDTSVSVTLGKMRSLHALGEWEQLSQLAARKWKVSKLQTKKLIAPLAAGAAWGLGEWDMLEQYISVMKPKSPDKEFFDAILYLHKNDYDNASKHILNARDLLVTEISALINESYNRAYSVIVRTQIITEFEEIIKYKQLPPNSEKKLHYQNLWTKRLLGCQKNVDLWQRVLRVRSLVIKPKQDLQIWIKFANLCRKSGRMRLANKALNMLLEGGNDPSLPNTFKAPPPVVYAQLKYIWATGAYKEALNHLIGFTSRLAHDLGLDPNNMIAQSVKLSSASTAPYVEEYTKLLARCFLKQGEWRIATQPNWRNTNPDAILGSYLLATHFDKNWYKAWHNWALANFEVISMVQEETKLNGGKNDDDDDTAVNNDNVRIDGSILGSGSLTINGNRYPLELIQRHVVPAIKGFFHSISLLETSCLQDTLRLLTLLFNFGGIKEVSQAMYEGFNLMKIENWLEVLPQLISRIHQPDPTVSNSLLSLLSDLGKAHPQALVYPLTVAIKSESVSRQKAALSIIEKIRIHSPVLVNQAELVSHELIRVAVLWHELWYEGLEDASRQFFVEHNIEKMFSTLEPLHKHLGNEPQ…
SIO_010081: YJR066W
subclass of: SO_0000673
so part of: YJR066W
location: 559416..566828
location: region:559416-566828:1
so has part: feature:559416-566828:1:exon

NP_012600.1
type: Protein
SIO_000068: ncbiprotein

S000003827
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:559416-566828:1:exon

YJR067C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: YAE1
locus tag: YJR067C
so part of: sequence
location: complement(<567019..>567444)
location: region:567019-567444:-1
so has part: feature:567019-567444:-1:exon
subclass of: SO_0000010

853530
type: Gene
SIO_000068: ncbigene

position:567019:-1
position: 567019
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:567444:-1
position: 567444
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:567019-567444:-1:exon

YJR067C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: YAE1
locus tag: YJR067C
product: Yae1p
transcript id: NM_001181725.1
SIO_010081: YJR067C
subclass of: SO_0000673
so part of: YJR067C
location: complement(<567019..>567444)
location: region:567019-567444:-1
so has part: feature:567019-567444:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:567019-567444:-1:exon

YJR067C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: YAE1
locus tag: YJR067C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0030674 protein-macromolecule adaptor activity [PMID:26182403]
experiment: EXISTENCE:direct assay:GO:0062092 Yae1-Lto1 complex [PMID:26182403]
experiment: EXISTENCE:mutant phenotype:GO:0106035 protein maturation by [4Fe-4S] cluster transfer [PMID:26182403]
note: Substrate-specific adaptor protein involved in apo-Rli1p maturation; subunit of the Yae1-Lto1 complex, recruiting apo-Rli1p to the CIA targeting complex, facilitating the insertion of an Fe/S cluster by the Fe-S biosynthetic machinery; deca-GX3 motif crucial for complex formation; essential for aerobic but not anaerobic growth; homolog of human YAE1D1, which is overexpressed in oral cancers; co-expression of YAE1D1 and LTO1 homolog ORAOV1 restores growth and Rli1p maturation after YAE1 depletion
codon start: 1
product: Yae1p
translation: MSNTWDDVWASDSDVETERSPDLVKLRENHSKRGYLDGIVSSKEEKLQEGFNDGFPTGAKLGKQVGIIMGILLGLRTRFGDEDEDLSKAYIDAQKELRINKVLSKSIFDPNFDLQEKHPLITKWTDIANTYCEKYHVPSIQ
SIO_010081: YJR067C
subclass of: SO_0000673
so part of: YJR067C
location: complement(567019..567444)
location: region:567019-567444:-1
so has part: feature:567019-567444:-1:exon

NP_012601.1
type: Protein
SIO_000068: ncbiprotein

S000003828
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:567019-567444:-1:exon

YJR068W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RFC2
locus tag: YJR068W
so part of: sequence
location: <567643..>568704
location: region:567643-568704:1
so has part: feature:567643-568704:1:exon
subclass of: SO_0000010

853531
type: Gene
SIO_000068: ncbigene

position:567643:1
position: 567643
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:568704:1
position: 568704
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:567643-568704:1:exon

YJR068W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RFC2
locus tag: YJR068W
product: replication factor C subunit 2
transcript id: NM_001181726.3
SIO_010081: YJR068W
subclass of: SO_0000673
so part of: YJR068W
location: <567643..>568704
location: region:567643-568704:1
so has part: feature:567643-568704:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:567643-568704:1:exon

YJR068W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RFC2
locus tag: YJR068W
experiment: EXISTENCE:direct assay:GO:0003689 DNA clamp loader activity [PMID:12604797|PMID:8995429]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:23613772]
experiment: EXISTENCE:direct assay:GO:0005663 DNA replication factor C complex [PMID:8202350]
experiment: EXISTENCE:direct assay:GO:0006272 leading strand elongation [PMID:1346062]
experiment: EXISTENCE:direct assay:GO:0031389 Rad17 RFC-like complex [PMID:12604797|PMID:10660302]
experiment: EXISTENCE:mutant phenotype:GO:0000076 DNA replication checkpoint signaling [PMID:9671499]
experiment: EXISTENCE:physical interaction:GO:0007062 sister chromatid cohesion [PMID:11389843]
experiment: EXISTENCE:physical interaction:GO:0031389 Rad17 RFC-like complex [PMID:10660302]
experiment: EXISTENCE:physical interaction:GO:0031390 Ctf18 RFC-like complex [PMID:11389843]
experiment: EXISTENCE:physical interaction:GO:0031391 Elg1 RFC-like complex [PMID:12912927]
note: Subunit of heteropentameric Replication factor C (RF-C); RF-C is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon
codon start: 1
product: replication factor C subunit 2
translation: MFEGFGPNKKRKISKLAAEQSLAQQPWVEKYRPKNLDEVTAQDHAVTVLKKTLKSANLPHMLFYGPPGTGKTSTILALTKELYGPDLMKSRILELNASDERGISIVREKVKNFARLTVSKPSKHDLENYPCPPYKIIILDEADSMTADAQSALRRTMETYSGVTRFCLICNYVTRIIDPLASRCSKFRFKALDASNAIDRLRFISEQENVKCDDGVLERILDISAGDLRRGITLLQSASKGAQYLGDGKNITSTQVEELAGVVPHDILIEIVEKVKSGDFDEIKKYVNTFMKSGWSAASVVNQLHEYYITNDNFDTNFKNQISWLLFTTDSRLNNGTNEHIQLLNLLVKISQL
SIO_010081: YJR068W
subclass of: SO_0000673
so part of: YJR068W
location: 567643..568704
location: region:567643-568704:1
so has part: feature:567643-568704:1:exon

NP_012602.3
type: Protein
SIO_000068: ncbiprotein

S000003829
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:567643-568704:1:exon

YJR069C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HAM1
locus tag: YJR069C
so part of: sequence
location: complement(<568806..>569399)
location: region:568806-569399:-1
so has part: feature:568806-569399:-1:exon
subclass of: SO_0000010

853532
type: Gene
SIO_000068: ncbigene

position:568806:-1
position: 568806
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:569399:-1
position: 569399
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:568806-569399:-1:exon

YJR069C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HAM1
locus tag: YJR069C
product: nucleoside triphosphate pyrophosphohydrolase HAM1
transcript id: NM_001181727.1
SIO_010081: YJR069C
subclass of: SO_0000673
so part of: YJR069C
location: complement(<568806..>569399)
location: region:568806-569399:-1
so has part: feature:568806-569399:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:568806-569399:-1:exon

YJR069C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: HAM1
locus tag: YJR069C
EC number: 3.6.1.9
experiment: EXISTENCE:direct assay:GO:0004170 dUTP diphosphatase activity [PMID:17899088]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0008828 dATP diphosphatase activity [PMID:22531138]
experiment: EXISTENCE:direct assay:GO:0009213 pyrimidine deoxyribonucleoside triphosphate catabolic process [PMID:17899088|PMID:22531138]
experiment: EXISTENCE:direct assay:GO:0009217 purine deoxyribonucleoside triphosphate catabolic process [PMID:17090528|PMID:17899088|PMID:22531138]
experiment: EXISTENCE:direct assay:GO:0035870 dITP diphosphatase activity [PMID:17090528|PMID:22531138]
experiment: EXISTENCE:direct assay:GO:0036217 dGTP diphosphatase activity [PMID:17090528|PMID:22531138]
experiment: EXISTENCE:direct assay:GO:0036218 dTTP diphosphatase activity [PMID:22531138]
experiment: EXISTENCE:direct assay:GO:0036219 GTP diphosphatase activity [PMID:22531138]
experiment: EXISTENCE:direct assay:GO:0036220 ITP diphosphatase activity [PMID:17899088|PMID:22531138]
experiment: EXISTENCE:direct assay:GO:0036221 UTP diphosphatase activity [PMID:17899088]
experiment: EXISTENCE:direct assay:GO:0036222 XTP diphosphatase activity [PMID:22531138]
experiment: EXISTENCE:direct assay:GO:0047840 dCTP diphosphatase activity [PMID:22531138]
experiment: EXISTENCE:mutant phenotype:GO:0009213 pyrimidine deoxyribonucleoside triphosphate catabolic process [PMID:17899088]
experiment: EXISTENCE:mutant phenotype:GO:0009217 purine deoxyribonucleoside triphosphate catabolic process [PMID:22308425]
note: Nucleoside triphosphate pyrophosphohydrolase; active against various substrates including ITP, dITP and XTP; mediates exclusion of non canonical purines, pyrimidines from dNTP pools; functions with YJL055W to mediate resistance to 5-FU; specifically reduces the incorporation of 5-FU into RNA without affecting uptake or incorporation of uracil into RNA; protein abundance increases in response to DNA replication stress; yeast HAM1 can complement knockdown of human homolog ITPA
codon start: 1
product: nucleoside triphosphate pyrophosphohydrolase HAM1
translation: MSNNEIVFVTGNANKLKEVQSILTQEVDNNNKTIHLINEALDLEELQDTDLNAIALAKGKQAVAALGKGKPVFVEDTALRFDEFNGLPGAYIKWFLKSMGLEKIVKMLEPFENKNAEAVTTICFADSRGEYHFFQGITRGKIVPSRGPTTFGWDSIFEPFDSHGLTYAEMSKDAKNAISHRGKAFAQFKEYLYQNDF
SIO_010081: YJR069C
subclass of: SO_0000673
so part of: YJR069C
location: complement(568806..569399)
location: region:568806-569399:-1
so has part: feature:568806-569399:-1:exon

NP_012603.1
type: Protein
SIO_000068: ncbiprotein

S000003830
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:568806-569399:-1:exon

YJR070C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MMD1
gene: LIA1
locus tag: YJR070C
gene synonym: MMD1
so part of: sequence
location: complement(<569621..>570598)
location: region:569621-570598:-1
so has part: feature:569621-570598:-1:exon
subclass of: SO_0000010

853534
type: Gene
SIO_000068: ncbigene

position:569621:-1
position: 569621
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:570598:-1
position: 570598
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:569621-570598:-1:exon

YJR070C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MMD1
gene: LIA1
locus tag: YJR070C
gene synonym: MMD1
product: deoxyhypusine monooxygenase
transcript id: NM_001181728.1
SIO_010081: YJR070C
subclass of: SO_0000673
so part of: YJR070C
location: complement(<569621..>570598)
location: region:569621-570598:-1
so has part: feature:569621-570598:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:569621-570598:-1:exon

YJR070C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MMD1
gene: LIA1
locus tag: YJR070C
gene synonym: MMD1
EC number: 1.14.99.29
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0008612 peptidyl-lysine modification to peptidyl-hypusine [PMID:16371467]
experiment: EXISTENCE:direct assay:GO:0019135 deoxyhypusine monooxygenase activity [PMID:16371467]
experiment: EXISTENCE:mutant phenotype:GO:0000226 microtubule cytoskeleton organization [PMID:14767070]
experiment: EXISTENCE:mutant phenotype:GO:0008612 peptidyl-lysine modification to peptidyl-hypusine [PMID:16371467]
experiment: EXISTENCE:mutant phenotype:GO:0019135 deoxyhypusine monooxygenase activity [PMID:16371467]
note: Deoxyhypusine hydroxylase; HEAT-repeat containing metalloenzyme that catalyzes hypusine formation; binds to and is required for the modification of Hyp2p (eIF5A); complements S. pombe mmd1 mutants defective in mitochondrial positioning; protein abundance increases in response to DNA replication stress
codon start: 1
product: deoxyhypusine monooxygenase
translation: MSTNFEKHFQENVDECTLEQLRDILVNKSGKTVLANRFRALFNLKTVAEEFATKPEEAKKAIEYIAESFVNDKSELLKHEVAYVLGQTKNLDAAPTLRHVMLDQNQEPMVRHEAAEALGALGDKDSLDDLNKAAKEDPHVAVRETCELAINRINWTHGGAKDKENLQQSLYSSIDPAPPLPLEKDATIPELQALLNDPKQPLFQRYRAMFRLRDIGTDEAILALATGFSAESSLFKHEIAYVFGQIGSPAAVPSLIEVLGRKEEAPMVRHEAAEALGAIASPEVVDVLKSYLNDEVDVVRESCIVALDMYDYENSNELEYAPTAN
SIO_010081: YJR070C
subclass of: SO_0000673
so part of: YJR070C
location: complement(569621..570598)
location: region:569621-570598:-1
so has part: feature:569621-570598:-1:exon

NP_012604.1
type: Protein
SIO_000068: ncbiprotein

S000003831
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:569621-570598:-1:exon

YJR072C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: EPA1
alternative label: GPN1
gene: NPA3
locus tag: YJR072C
gene synonym: EPA1; GPN1
so part of: sequence
location: complement(<570967..>572124)
location: region:570967-572124:-1
so has part: feature:570967-572124:-1:exon
subclass of: SO_0000010

853535
type: Gene
SIO_000068: ncbigene

position:570967:-1
position: 570967
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:572124:-1
position: 572124
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:570967-572124:-1:exon

YJR072C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: EPA1
alternative label: GPN1
gene: NPA3
locus tag: YJR072C
gene synonym: EPA1; GPN1
product: GTPase NPA3
transcript id: NM_001181730.3
SIO_010081: YJR072C
subclass of: SO_0000673
so part of: YJR072C
location: complement(<570967..>572124)
location: region:570967-572124:-1
so has part: feature:570967-572124:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:570967-572124:-1:exon

YJR072C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: EPA1
alternative label: GPN1
gene: NPA3
locus tag: YJR072C
gene synonym: EPA1; GPN1
experiment: EXISTENCE:direct assay:GO:0003924 GTPase activity [PMID:21844196]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0006913 nucleocytoplasmic transport [PMID:21844196]
experiment: EXISTENCE:direct assay:GO:0016887 ATP hydrolysis activity [PMID:15082539]
experiment: EXISTENCE:mutant phenotype:GO:0006606 protein import into nucleus [PMID:21844196]
experiment: EXISTENCE:mutant phenotype:GO:0007064 mitotic sister chromatid cohesion [PMID:21532343]
note: Member of the conserved GPN-loop GTPase family; has a role in transport of RNA polymerase II to the nucleus; exhibits GTP-dependent binding to PolII; has ATPase activity; involved in sister chromatid cohesion; phosphorylated by the Pcl1p-Pho85p kinase complex; human homolog XAB1 interacts with human RNA polymerase II; protein abundance increases in response to DNA replication stress
codon start: 1
product: GTPase NPA3
translation: MSLSTIICIGMAGSGKTTFMQRLNSHLRAEKTPPYVINLDPAVLRVPYGANIDIRDSIKYKKVMENYQLGPNGAIVTSLNLFSTKIDQVIRLVEQKKDKFQNCIIDTPGQIECFVWSASGAIITESFASSFPTVIAYIVDTPRNSSPTTFMSNMLYACSILYKTKLPMIVVFNKTDVCKADFAKEWMTDFESFQAAIKEDQDLNGDNGLGSGYMSSLVNSMSLMLEEFYSQLDVVGVSSFTGDGFDEFMQCVDKKVDEYDQYYKQEREKALNLKKKKEEMRKQKSLNGLMKDLGLNEKSSAAASDNDSIDAISDLEEDANDGLVDRDEDEGVEREYTFPGEERTKGEVNENSAPDLQRRYQEAMQQVGKTASSETAENIAKYIRN
SIO_010081: YJR072C
subclass of: SO_0000673
so part of: YJR072C
location: complement(570967..572124)
location: region:570967-572124:-1
so has part: feature:570967-572124:-1:exon

NP_012606.3
type: Protein
SIO_000068: ncbiprotein

S000003833
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:570967-572124:-1:exon

YJR073C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PEM2
gene: OPI3
locus tag: YJR073C
gene synonym: PEM2
so part of: sequence
location: complement(<572315..>572935)
location: region:572315-572935:-1
so has part: feature:572315-572935:-1:exon
subclass of: SO_0000010

853536
type: Gene
SIO_000068: ncbigene

position:572315:-1
position: 572315
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:572935:-1
position: 572935
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:572315-572935:-1:exon

YJR073C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PEM2
gene: OPI3
locus tag: YJR073C
gene synonym: PEM2
product: bifunctional phosphatidyl-N-methylethanolamine N-methyltransferase/phosphatidyl-N-dimethylethanolamine N-methyltransferase
transcript id: NM_001181731.1
SIO_010081: YJR073C
subclass of: SO_0000673
so part of: YJR073C
location: complement(<572315..>572935)
location: region:572315-572935:-1
so has part: feature:572315-572935:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:572315-572935:-1:exon

YJR073C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PEM2
gene: OPI3
locus tag: YJR073C
gene synonym: PEM2
EC number: 2.1.1.17
EC number: 2.1.1.71
experiment: EXISTENCE:direct assay:GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity [PMID:2445736]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0006656 phosphatidylcholine biosynthetic process [PMID:2445736]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0080101 phosphatidyl-N-dimethylethanolamine N-methyltransferase activity [PMID:2445736]
experiment: EXISTENCE:genetic interaction:GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity [PMID:2445736]
experiment: EXISTENCE:genetic interaction:GO:0006656 phosphatidylcholine biosynthetic process [PMID:2445736]
experiment: EXISTENCE:genetic interaction:GO:0080101 phosphatidyl-N-dimethylethanolamine N-methyltransferase activity [PMID:2445736]
experiment: EXISTENCE:mutant phenotype:GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity [PMID:2684666]
experiment: EXISTENCE:mutant phenotype:GO:0006656 phosphatidylcholine biosynthetic process [PMID:6337128|PMID:23000174]
experiment: EXISTENCE:mutant phenotype:GO:0080101 phosphatidyl-N-dimethylethanolamine N-methyltransferase activity [PMID:2684666]
note: Methylene-fatty-acyl-phospholipid synthase; catalyzes the last two steps in phosphatidylcholine biosynthesis; also known as phospholipid methyltransferase
codon start: 1
product: bifunctional phosphatidyl-N-methylethanolamine N-methyltransferase/phosphatidyl-N-dimethylethanolamine N-methyltransferase
translation: MKESVQEIIQQLIHSVDLQSSKFQLAIVCTMFNPIFWNIVARMEYHKHSLTKMCGGARKGCYMLAATIFSLGIVRDMVYESALREQPTCSLITGENWTKLGVALFGLGQVLVLSSMYKLGITGTYLGDYFGILMDERVTGFPFNVSNNPMYQGSTLSFLGIALYKGKPAGLVVSAVVYFMYKIALRWEEPFTAMIYANRDKAKKNM
SIO_010081: YJR073C
subclass of: SO_0000673
so part of: YJR073C
location: complement(572315..572935)
location: region:572315-572935:-1
so has part: feature:572315-572935:-1:exon

NP_012607.1
type: Protein
SIO_000068: ncbiprotein

S000003834
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:572315-572935:-1:exon

YJR074W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MOG1
locus tag: YJR074W
so part of: sequence
location: <573095..>573751
location: region:573095-573751:1
so has part: feature:573095-573751:1:exon
subclass of: SO_0000010

853537
type: Gene
SIO_000068: ncbigene

position:573095:1
position: 573095
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:573751:1
position: 573751
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:573095-573751:1:exon

YJR074W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MOG1
locus tag: YJR074W
product: Ran GTPase-binding protein MOG1
transcript id: NM_001181732.1
SIO_010081: YJR074W
subclass of: SO_0000673
so part of: YJR074W
location: <573095..>573751
location: region:573095-573751:1
so has part: feature:573095-573751:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:573095-573751:1:exon

YJR074W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MOG1
locus tag: YJR074W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:9860978]
experiment: EXISTENCE:direct assay:GO:0031267 small GTPase binding [PMID:11509570|PMID:9860978]
experiment: EXISTENCE:mutant phenotype:GO:0006606 protein import into nucleus [PMID:9860978|PMID:11024003]
note: Conserved nuclear protein that interacts with GTP-Gsp1p; stimulates nucleotide release from Gsp1p; involved in nuclear protein import; nucleotide release is inhibited by Yrb1p
codon start: 1
product: Ran GTPase-binding protein MOG1
translation: MKIEKASHISQPVQLSTCTLIDTYPGHQGSMNNKEVELYGGAITTVVPPGFIDASTLREVPDTQEVYVNSRRDEEEFEDGLATNESIIVDLLETVDKSDLKEAWQFHVEDLTELNGTTKWEALQEDTVQQGTKFTGLVMEVANKWGKPDLAQTVVIGVALIRLTQFDTDVVISINVPLTKEEASQASNKELPARCHAVYQLLQEMVRKFHVVDTSLFA
SIO_010081: YJR074W
subclass of: SO_0000673
so part of: YJR074W
location: 573095..573751
location: region:573095-573751:1
so has part: feature:573095-573751:1:exon

NP_012608.1
type: Protein
SIO_000068: ncbiprotein

S000003835
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:573095-573751:1:exon

YJR075W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HOC1
locus tag: YJR075W
so part of: sequence
location: <573981..>575171
location: region:573981-575171:1
so has part: feature:573981-575171:1:exon
subclass of: SO_0000010

853538
type: Gene
SIO_000068: ncbigene

position:573981:1
position: 573981
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:575171:1
position: 575171
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:573981-575171:1:exon

YJR075W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HOC1
locus tag: YJR075W
product: alpha-1,6-mannosyltransferase
transcript id: NM_001181733.3
SIO_010081: YJR075W
subclass of: SO_0000673
so part of: YJR075W
location: <573981..>575171
location: region:573981-575171:1
so has part: feature:573981-575171:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:573981-575171:1:exon

YJR075W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: HOC1
locus tag: YJR075W
experiment: EXISTENCE:direct assay:GO:0000009 alpha-1,6-mannosyltransferase activity [PMID:10037752]
experiment: EXISTENCE:direct assay:GO:0000136 mannan polymerase complex [PMID:10037752]
experiment: EXISTENCE:physical interaction:GO:0000136 mannan polymerase complex [PMID:9430634]
note: Alpha-1,6-mannosyltransferase; involved in cell wall mannan biosynthesis; subunit of a Golgi-localized complex that also contains Anp1p, Mnn9p, Mnn11p, and Mnn10p; identified as a suppressor of a cell lysis sensitive pkc1-371 allele
codon start: 1
product: alpha-1,6-mannosyltransferase
translation: MAKTTKRASSFRRLMIFAIIALISLAFGVRYLFHNSNATDLQKILQNLPKEISQSINSANNIQSSDSDLVQHFESLAQEIRHQQEVQAKQFDKQRKILEKKIQDLKQTPPEATLRERIAMTFPYDSHVKFPAFIWQTWSNDEGPERVQDIKGMWESKNPGFAHEVLNHDVINALVHHYFYSIPEILETYEALPSIILKIDFFKYLILLVHGGVYADIDTFPVQPIPNWIPEELSPSDIGLIVGVEEDAQRADWRTKYIRRLQFGTWIIQAKPGHPVLREIISRIIETTLQRKRDDQLNVNLRNDLNIMSWTGSGLWTDTIFTYFNDFMRSGVREKVTWKLFHNLNQPKLLSDVLVFPKFSFNCPNQIDNDDPHKKFYFITHLASQFWKNTPKVEQK
SIO_010081: YJR075W
subclass of: SO_0000673
so part of: YJR075W
location: 573981..575171
location: region:573981-575171:1
so has part: feature:573981-575171:1:exon

NP_012609.3
type: Protein
SIO_000068: ncbiprotein

S000003836
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:573981-575171:1:exon

YJR076C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PSL9
gene: CDC11
locus tag: YJR076C
gene synonym: PSL9
so part of: sequence
location: complement(<575354..>576601)
location: region:575354-576601:-1
so has part: feature:575354-576601:-1:exon
subclass of: SO_0000010

853539
type: Gene
SIO_000068: ncbigene

position:575354:-1
position: 575354
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:576601:-1
position: 576601
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:575354-576601:-1:exon

YJR076C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PSL9
gene: CDC11
locus tag: YJR076C
gene synonym: PSL9
product: septin CDC11
transcript id: NM_001181734.1
SIO_010081: YJR076C
subclass of: SO_0000673
so part of: YJR076C
location: complement(<575354..>576601)
location: region:575354-576601:-1
so has part: feature:575354-576601:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:575354-576601:-1:exon

YJR076C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PSL9
gene: CDC11
locus tag: YJR076C
gene synonym: PSL9
experiment: EXISTENCE:curator inference:GO:0030011 maintenance of cell polarity [PMID:10882120]
experiment: EXISTENCE:direct assay:GO:0000144 cellular bud neck septin ring [PMID:1934633]
experiment: EXISTENCE:direct assay:GO:0001400 mating projection base [PMID:8791410]
experiment: EXISTENCE:direct assay:GO:0005200 structural constituent of cytoskeleton [PMID:18550837|PMID:22144691|PMID:29321251]
experiment: EXISTENCE:direct assay:GO:0005525 GTP binding [PMID:12665577]
experiment: EXISTENCE:direct assay:GO:0005619 ascospore wall [PMID:8636217]
experiment: EXISTENCE:direct assay:GO:0005628 prospore membrane [PMID:18826657|PMID:24390141]
experiment: EXISTENCE:direct assay:GO:0005876 spindle microtubule [PMID:18826657]
experiment: EXISTENCE:direct assay:GO:0005881 cytoplasmic microtubule [PMID:18826657]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0010314 phosphatidylinositol-5-phosphate binding [PMID:12665577]
experiment: EXISTENCE:direct assay:GO:0031105 septin complex [PMID:18550837]
experiment: EXISTENCE:direct assay:GO:0032160 septin filament array [PMID:15282341]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:19053807]
experiment: EXISTENCE:direct assay:GO:0045860 positive regulation of protein kinase activity [PMID:14527412]
experiment: EXISTENCE:direct assay:GO:0070273 phosphatidylinositol-4-phosphate binding [PMID:12665577]
experiment: EXISTENCE:direct assay:GO:0072687 meiotic spindle [PMID:18826657]
experiment: EXISTENCE:genetic interaction:GO:0097271 protein localization to bud neck [PMID:25971666]
experiment: EXISTENCE:mutant phenotype:GO:0000281 mitotic cytokinesis [PMID:4950437]
experiment: EXISTENCE:mutant phenotype:GO:0010314 phosphatidylinositol-5-phosphate binding [PMID:12665577]
experiment: EXISTENCE:mutant phenotype:GO:0070273 phosphatidylinositol-4-phosphate binding [PMID:12665577]
experiment: EXISTENCE:physical interaction:GO:0031105 septin complex [PMID:9813094]
note: Component of the septin ring that is required for cytokinesis; present at the ends of rod-like septin hetero-oligomers; C-terminal extension is important for recruitment of Bni5p to the mother-bud neck, which in turn is required for Myo1p recruitment and cytokinesis; septin rings at the mother-bud neck act as scaffolds for recruiting cell division factors and as barriers to prevent diffusion of specific proteins between mother and daughter cells
codon start: 1
product: septin CDC11
translation: MSGIIDASSALRKRKHLKRGITFTVMIVGQSGSGRSTFINTLCGQQVVDTSTTILLPTDTSTEIDLQLREETVELEDDEGVKIQLNIIDTPGFGDSLDNSPSFEIISDYIRHQYDEILLEESRVRRNPRFKDGRVHCCLYLINPTGHGLKEIDVEFIRQLGSLVNIIPVISKSDSLTRDELKLNKKLIMEDIDRWNLPIYNFPFDEDEISDEDYETNMYLRTLLPFAIIGSNEVYEMGGDVGTIRGRKYPWGILDVEDSSISDFVILRNALLISHLHDLKNYTHEILYERYRTEALSGESVAAESIRPNLTKLNGSSSSSTTTRRNTNPFKQSNNINNDVLNPASDMHGQSTGENNETYMTREEQIRLEEERLKAFEERVQQELLLKRQELLQREKELREIEARLEKEAKIKQEE
SIO_010081: YJR076C
subclass of: SO_0000673
so part of: YJR076C
location: complement(575354..576601)
location: region:575354-576601:-1
so has part: feature:575354-576601:-1:exon

NP_012610.1
type: Protein
SIO_000068: ncbiprotein

S000003837
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:575354-576601:-1:exon

YJR077C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MIR1
locus tag: YJR077C
so part of: sequence
location: complement(<577255..>578190)
location: region:577255-578190:-1
so has part: feature:577255-578190:-1:exon
subclass of: SO_0000010

853540
type: Gene
SIO_000068: ncbigene

position:577255:-1
position: 577255
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:578190:-1
position: 578190
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:577255-578190:-1:exon

YJR077C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MIR1
locus tag: YJR077C
product: Mir1p
transcript id: NM_001181735.1
SIO_010081: YJR077C
subclass of: SO_0000673
so part of: YJR077C
location: complement(<577255..>578190)
location: region:577255-578190:-1
so has part: feature:577255-578190:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:577255-578190:-1:exon

YJR077C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MIR1
locus tag: YJR077C
experiment: EXISTENCE:direct assay:GO:0005315 inorganic phosphate transmembrane transporter activity [PMID:9099701]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:11914276|PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005743 mitochondrial inner membrane [PMID:8245029]
experiment: EXISTENCE:direct assay:GO:0035435 phosphate ion transmembrane transport [PMID:9099701]
experiment: EXISTENCE:physical interaction:GO:0005739 mitochondrion [PMID:16962558]
note: Mitochondrial phosphate carrier; imports inorganic phosphate into mitochondria; functionally redundant with Pic2p but more abundant than Pic2p under normal conditions; phosphorylated
codon start: 1
product: Mir1p
translation: MSVSAAPAIPQYSVSDYMKFALAGAIGCGSTHSSMVPIDVVKTRIQLEPTVYNKGMVGSFKQIIAGEGAGALLTGFGPTLLGYSIQGAFKFGGYEVFKKFFIDNLGYDTASRYKNSVYMGSAAMAEFLADIALCPLEATRIRLVSQPQFANGLVGGFSRILKEEGIGSFYSGFTPILFKQIPYNIAKFLVFERASEFYYGFAGPKEKLSSTSTTLLNLLSGLTAGLAAAIVSQPADTLLSKVNKTKKAPGQSTVGLLAQLAKQLGFFGSFAGLPTRLVMVGTLTSLQFGIYGSLKSTLGCPPTIEIGGGGH
SIO_010081: YJR077C
subclass of: SO_0000673
so part of: YJR077C
location: complement(577255..578190)
location: region:577255-578190:-1
so has part: feature:577255-578190:-1:exon

NP_012611.1
type: Protein
SIO_000068: ncbiprotein

S000003838
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:577255-578190:-1:exon

YJR078W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: BNA2
locus tag: YJR078W
so part of: sequence
location: <578860..>580221
location: region:578860-580221:1
so has part: feature:578860-580221:1:exon
subclass of: SO_0000010

853541
type: Gene
SIO_000068: ncbigene

position:578860:1
position: 578860
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:580221:1
position: 580221
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:578860-580221:1:exon

YJR078W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: BNA2
locus tag: YJR078W
product: dioxygenase BNA2
transcript id: NM_001181736.3
SIO_010081: YJR078W
subclass of: SO_0000673
so part of: YJR078W
location: <578860..>580221
location: region:578860-580221:1
so has part: feature:578860-580221:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:578860-580221:1:exon

YJR078W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: BNA2
locus tag: YJR078W
EC number: 1.13.11.52
experiment: EXISTENCE:curator inference:GO:0019441 tryptophan catabolic process to kynurenine [PMID:21170645]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0033754 indoleamine 2,3-dioxygenase activity [PMID:21170645]
experiment: EXISTENCE:genetic interaction:GO:0034354 'de novo' NAD biosynthetic process from tryptophan [PMID:12062417]
note: Tryptophan 2,3-dioxygenase or indoleamine 2,3-dioxygenase; required for de novo biosynthesis of NAD+ from tryptophan via kynurenine; up-regulated by telomere uncapping, and interacts genetically with capping gene CDC13; overexpression reduces lipid droplet accumulation by skewing glycolytic flux towards biosynthesis of shikimate, aromatic amino acids, and NAD+ during aging and extends lifespan; regulated by Hst1p and Aftp
codon start: 1
product: dioxygenase BNA2
translation: MNNTSITGPQVLHRTKMRPLPVLEKYCISPHHGFLDDRLPLTRLSSKKYMKWEEIVADLPSLLQEDNKVRSVIDGLDVLDLDETILGDVRELRRAYSILGFMAHAYIWASGTPRDVLPECIARPLLETAHILGVPPLATYSSLVLWNFKVTDECKKTETGCLDLENITTINTFTGTVDESWFYLVSVRFEKIGSACLNHGLQILRAIRSGDKGDANVIDGLEGLAATIERLSKALMEMELKCEPNVFYFKIRPFLAGWTNMSHMGLPQGVRYGAEGQYRIFSGGSNAQSSLIQTLDILLGVKHTANAAHSSQGDSKINYLDEMKKYMPREHREFLYHLESVCNIREYVSRNASNRALQEAYGRCISMLKIFRDNHIQIVTKYIILPSNSKQHGSNKPNVLSPIEPNTKASGCLGHKVASSKTIGTGGTRLMPFLKQCRDETVATADIKNEDKN
SIO_010081: YJR078W
subclass of: SO_0000673
so part of: YJR078W
location: 578860..580221
location: region:578860-580221:1
so has part: feature:578860-580221:1:exon

NP_012612.3
type: Protein
SIO_000068: ncbiprotein

S000003839
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:578860-580221:1:exon

YJR079W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJR079W
so part of: sequence
location: <580205..>581239
location: region:580205-581239:1
so has part: feature:580205-581239:1:exon
subclass of: SO_0000010

853542
type: Gene
SIO_000068: ncbigene

position:580205:1
position: 580205
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:581239:1
position: 581239
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:580205-581239:1:exon

YJR079W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJR079W
product: uncharacterized protein
transcript id: NM_001181737.1
SIO_010081: YJR079W
subclass of: SO_0000673
so part of: YJR079W
location: join(<580205..580347,581053..>581239)
location: region:580205-581239:1
so has part: feature:580205-580347:1:exon
so has part: feature:581053-581239:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:580205-580347:1:exon

position:580347:1
position: 580347
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:581053-581239:1:exon

position:581053:1
position: 581053
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YJR079W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJR079W
note: hypothetical protein; mutation results in impaired mitochondrial respiration
codon start: 1
product: uncharacterized protein
translation: MKIKIDIIHFINAPPFFFFFVDAEASQLKAFQLFLLGHIFYTYIHTYICDFDEFETKDLAEGKIGDLISRLEFCSNAIIESLPNTFQSFVPVKFSTDKLLEESKGLLDV
SIO_010081: YJR079W
subclass of: SO_0000673
so part of: YJR079W
location: join(580205..580347,581053..581239)
location: region:580205-581239:1
so has part: feature:580205-580347:1:exon
so has part: feature:581053-581239:1:exon

NP_012613.1
type: Protein
SIO_000068: ncbiprotein

S000003840
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:580205-580347:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:581053-581239:1:exon

YJR080C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: FMP26
gene: AIM24
locus tag: YJR080C
gene synonym: FMP26
so part of: sequence
location: complement(<580432..>581616)
location: region:580432-581616:-1
so has part: feature:580432-581616:-1:exon
subclass of: SO_0000010

853543
type: Gene
SIO_000068: ncbigene

position:580432:-1
position: 580432
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:581616:-1
position: 581616
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:580432-581616:-1:exon

YJR080C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: FMP26
gene: AIM24
locus tag: YJR080C
gene synonym: FMP26
product: Aim24p
transcript id: NM_001181738.1
SIO_010081: YJR080C
subclass of: SO_0000673
so part of: YJR080C
location: complement(<580432..>581616)
location: region:580432-581616:-1
so has part: feature:580432-581616:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:580432-581616:-1:exon

YJR080C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: FMP26
gene: AIM24
locus tag: YJR080C
gene synonym: FMP26
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095|PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005743 mitochondrial inner membrane [PMID:24714493]
experiment: EXISTENCE:mutant phenotype:GO:0007007 inner mitochondrial membrane organization [PMID:24714493]
note: Protein with a role in determining mitochondrial architecture; inner membrane protein that interacts physically and genetically with the MICOS complex and is required for its integrity
codon start: 1
product: Aim24p
translation: MISPRVNTRVWQRSISLLSPQAAKTESNVVTKERTYIENLSKDIATSRFRLVDENGKIASITVQPDIPICIKKDCLVSIHNLNHLSLSYKWLNFWSNLIKFRSFKSSLFHRIIGSSVLEILAAPNFQTSRRPFDSSRSLSVLNLTGTKDWNVFGKDSIIAFEQNSSLEIKSPIFPSARSLVSNSSKSQLPRKFQILNGRGNVLVCGGGLVYSIELIDESDKILVNSRNILAINGQSQLDIANSVERQELHVEGAYVGDSSNDTVAPKFIKNQTLKSAYGHTVQFFKRMRSWIRNQYEKRYIYGVDSYFMKIKGPRTILIQTHEMTTSKDNILTKLTSKGHVKKSNVNDNGVNLEKQVANDVNSKIIELANRPSLFIATVSQDGRVDFQSTSKFT
SIO_010081: YJR080C
subclass of: SO_0000673
so part of: YJR080C
location: complement(580432..581616)
location: region:580432-581616:-1
so has part: feature:580432-581616:-1:exon

NP_012614.1
type: Protein
SIO_000068: ncbiprotein

S000003841
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:580432-581616:-1:exon

YJR082C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: EAF6
locus tag: YJR082C
so part of: sequence
location: complement(<581914..>582255)
location: region:581914-582255:-1
so has part: feature:581914-582255:-1:exon
subclass of: SO_0000010

853544
type: Gene
SIO_000068: ncbigene

position:581914:-1
position: 581914
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:582255:-1
position: 582255
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:581914-582255:-1:exon

YJR082C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: EAF6
locus tag: YJR082C
product: Eaf6p
transcript id: NM_001181739.3
SIO_010081: YJR082C
subclass of: SO_0000673
so part of: YJR082C
location: complement(<581914..>582255)
location: region:581914-582255:-1
so has part: feature:581914-582255:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:581914-582255:-1:exon

YJR082C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: EAF6
locus tag: YJR082C
experiment: EXISTENCE:curator inference:GO:0004402 histone acetyltransferase activity [PMID:17157260]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0006281 DNA repair [PMID:16135807]
experiment: EXISTENCE:direct assay:GO:0033100 NuA3 histone acetyltransferase complex [PMID:17157260]
experiment: EXISTENCE:direct assay:GO:0035267 NuA4 histone acetyltransferase complex [PMID:15485911]
experiment: EXISTENCE:direct assay:GO:1990467 NuA3a histone acetyltransferase complex [PMID:25104842]
experiment: EXISTENCE:direct assay:GO:1990468 NuA3b histone acetyltransferase complex [PMID:25104842]
experiment: EXISTENCE:physical interaction:GO:0016573 histone acetylation [PMID:17157260]
note: Subunit of the NuA4 acetyltransferase complex; this complex acetylates histone H4 and NuA3 acetyltransferase complex that acetylates histone H3
codon start: 1
product: Eaf6p
translation: MTDELKSYEALKAELKKSLQDRREQEDTFDNLQQEIYDKETEYFSHNSNNNHSGHGGAHGSKSHYSGNIIKGFDTFSKSHHSHADSAFNNNDRIFSLSSATYVKQQHGQSQND
SIO_010081: YJR082C
subclass of: SO_0000673
so part of: YJR082C
location: complement(581914..582255)
location: region:581914-582255:-1
so has part: feature:581914-582255:-1:exon

NP_012615.3
type: Protein
SIO_000068: ncbiprotein

S000003842
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:581914-582255:-1:exon

YJR083C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ACF4
locus tag: YJR083C
so part of: sequence
location: complement(<582608..>583537)
location: region:582608-583537:-1
so has part: feature:582608-583537:-1:exon
subclass of: SO_0000010

853545
type: Gene
SIO_000068: ncbigene

position:582608:-1
position: 582608
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:583537:-1
position: 583537
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:582608-583537:-1:exon

YJR083C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ACF4
locus tag: YJR083C
product: Acf4p
transcript id: NM_001181740.1
SIO_010081: YJR083C
subclass of: SO_0000673
so part of: YJR083C
location: complement(<582608..>583537)
location: region:582608-583537:-1
so has part: feature:582608-583537:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:582608-583537:-1:exon

YJR083C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ACF4
locus tag: YJR083C
note: hypothetical protein; computational analysis of large-scale protein-protein interaction data suggests a possible role in actin cytoskeleton organization; potential Cdc28p substrate
codon start: 1
product: Acf4p
translation: MSEDQRVISQPIELHKLSIVDKHSQGQQQQPHQKQHEVQPESKSPRVTTPLKPKRLAIPISSPQRSTTNQSPVSDHASPISTDQDLIYKLAAKHREINELSFKLEVAQKELKQLELQFKDTLPRNGQQKLGNQNPSEYLSTFTKRIQQTFVDVNNSPNMLKGKKSINDFFSKPNNNVNSNINNTLPNRKPNPPPNRSQRMQNIAPSRSSESTPTSGPPLLPPRNTMKNANTTATAGENTPFLQRILNKFNQMNMEEDEFDDLLEKRKSKKDHYYIKENLGYEYDEVRSEDEDDEEFEPMGDIPVHLFKR
SIO_010081: YJR083C
subclass of: SO_0000673
so part of: YJR083C
location: complement(582608..583537)
location: region:582608-583537:-1
so has part: feature:582608-583537:-1:exon

NP_012616.1
type: Protein
SIO_000068: ncbiprotein

S000003843
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:582608-583537:-1:exon

YJR084W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CSN12
locus tag: YJR084W
gene synonym: CSN12
so part of: sequence
location: <583733..>585004
location: region:583733-585004:1
so has part: feature:583733-585004:1:exon
subclass of: SO_0000010

853546
type: Gene
SIO_000068: ncbigene

position:583733:1
position: 583733
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:585004:1
position: 585004
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:583733-585004:1:exon

YJR084W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CSN12
locus tag: YJR084W
gene synonym: CSN12
product: uncharacterized protein
transcript id: NM_001181741.1
SIO_010081: YJR084W
subclass of: SO_0000673
so part of: YJR084W
location: <583733..>585004
location: region:583733-585004:1
so has part: feature:583733-585004:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:583733-585004:1:exon

YJR084W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CSN12
locus tag: YJR084W
gene synonym: CSN12
experiment: EXISTENCE:direct assay:GO:0000791 euchromatin [PMID:21149575]
experiment: EXISTENCE:mutant phenotype:GO:0000398 mRNA splicing, via spliceosome [PMID:19061648]
experiment: EXISTENCE:mutant phenotype:GO:0000754 adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion [PMID:12446563]
note: Protein that forms a complex with Thp3p; may have a role in transcription elongation and/or mRNA splicing; identified as a COP9 signalosome component but phenotype and interactions suggest it may not be involved with the signalosome
codon start: 1
product: uncharacterized protein
translation: MDVDIGCYFEEKRYDDKLLDFIRYDVKTPKKTKYILQRPTATDEESVRLQRFYQLGVDLKLKYSKRRSLKKQGRIKNATEELLRLANEQLKLFNRIVERETNWIIYPLWVMAKQLIRLANESSELNKDSIEECGRTIHRSFTICLNDRNPRLNENKKIGCYMFANLEFSIYHRLSNKDMIKNLVKVLESRVNARDIPPLNKSLAMEHKSQVVLYNYYLGQYYGCLENDHERGFFHLNEALLQCPMLYVESTGKFVLQGQMEKIMILLVPLALLTKRLYPHWDHPVIAGVITRSKRLSQVYPTLVRSVISGNLSLYEATAASHERFFLSQGLHVVITLLREVVFTRLVQRCWQWGNDRKSIMPLKILLATKQHDSSANEDEEEQLDALECRLASAIASGLLRAYLSHSNRCIVFSKKEPFPHSK
SIO_010081: YJR084W
subclass of: SO_0000673
so part of: YJR084W
location: 583733..585004
location: region:583733-585004:1
so has part: feature:583733-585004:1:exon

NP_012617.1
type: Protein
SIO_000068: ncbiprotein

S000003844
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:583733-585004:1:exon

YJR085C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TMH11
locus tag: YJR085C
so part of: sequence
location: complement(<585120..>585437)
location: region:585120-585437:-1
so has part: feature:585120-585437:-1:exon
subclass of: SO_0000010

853547
type: Gene
SIO_000068: ncbigene

position:585120:-1
position: 585120
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:585437:-1
position: 585437
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:585120-585437:-1:exon

YJR085C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TMH11
locus tag: YJR085C
product: Tmh11p
transcript id: NM_001181742.3
SIO_010081: YJR085C
subclass of: SO_0000673
so part of: YJR085C
location: complement(<585120..>585437)
location: region:585120-585437:-1
so has part: feature:585120-585437:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:585120-585437:-1:exon

YJR085C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TMH11
locus tag: YJR085C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
note: Mitochondrial hypothetical protein; GFP-fusion protein is induced in response to the DNA-damaging agent MMS; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; protein abundance increases in response to DNA replication stress
codon start: 1
product: Tmh11p
translation: MEHPAYTLSLLTTAGGLMGYYRKGSIPSLVSGLVFGSVYGIAGYLLHMNRDGGLEMALGASTLLLGAGVIRGMPSRFTKPVPVVLTALGGLGSYYYYNKYKEFYP
SIO_010081: YJR085C
subclass of: SO_0000673
so part of: YJR085C
location: complement(585120..585437)
location: region:585120-585437:-1
so has part: feature:585120-585437:-1:exon

NP_012618.3
type: Protein
SIO_000068: ncbiprotein

S000003845
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:585120-585437:-1:exon

YJR086W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: STE18
locus tag: YJR086W
so part of: sequence
location: <586068..>586400
location: region:586068-586400:1
so has part: feature:586068-586400:1:exon
subclass of: SO_0000010

853548
type: Gene
SIO_000068: ncbigene

position:586068:1
position: 586068
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:586400:1
position: 586400
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:586068-586400:1:exon

YJR086W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: STE18
locus tag: YJR086W
product: Ste18p
transcript id: NM_001181743.1
SIO_010081: YJR086W
subclass of: SO_0000673
so part of: YJR086W
location: <586068..>586400
location: region:586068-586400:1
so has part: feature:586068-586400:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:586068-586400:1:exon

YJR086W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: STE18
locus tag: YJR086W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:8995254]
experiment: EXISTENCE:direct assay:GO:0005834 heterotrimeric G-protein complex [PMID:8995254]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:8995254]
experiment: EXISTENCE:direct assay:GO:0031680 G-protein beta/gamma-subunit complex [PMID:8417317|PMID:8995254]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0120171 Cdc24p-Far1p-Gbetagamma complex [PMID:10087263]
experiment: EXISTENCE:genetic interaction:GO:0000750 pheromone-dependent signal transduction involved in conjugation with cellular fusion [PMID:2107073]
experiment: EXISTENCE:genetic interaction:GO:0031680 G-protein beta/gamma-subunit complex [PMID:8417317]
experiment: EXISTENCE:mutant phenotype:GO:0000750 pheromone-dependent signal transduction involved in conjugation with cellular fusion [PMID:3151178]
experiment: EXISTENCE:mutant phenotype:GO:0005834 heterotrimeric G-protein complex [PMID:2105453]
experiment: EXISTENCE:physical interaction:GO:0005515 protein binding [PMID:8649369]
experiment: EXISTENCE:physical interaction:GO:0031680 G-protein beta/gamma-subunit complex [PMID:8649369]
experiment: EXISTENCE:physical interaction:GO:0031681 G-protein beta-subunit binding [PMID:8417317|PMID:8649369]
note: G protein gamma subunit; forms dimer with Ste4p to activate mating signaling pathway, heterotrimer with Gpa1p, Ste4p to dampen signaling; C-terminus is palmitoylated and farnesylated, which are required for normal signaling; N-terminal phosphorylation of Ste18p functions synergistically with Fus3p docking site on Ste5p to restrict Ste5p plasma membrane recruitment and signaling; combinatorial phosphorylation at S3 and S7, by pheromone and pH stress, modulates Ste18p structure, Fus3p activation
codon start: 1
product: Ste18p
translation: MTSVQNSPRLQQPQEQQQQQQQLSLKIKQLKLKRINELNNKLRKELSRERITASNACLTIINYTSNTKDYTLPELWGYPVAGSNHFIEGLKNAQKNSQMSNSNSVCCTLM
SIO_010081: YJR086W
subclass of: SO_0000673
so part of: YJR086W
location: 586068..586400
location: region:586068-586400:1
so has part: feature:586068-586400:1:exon

NP_012619.1
type: Protein
SIO_000068: ncbiprotein

S000003846
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:586068-586400:1:exon

YJR088C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: EMC2
locus tag: YJR088C
so part of: sequence
location: complement(<586495..>587373)
location: region:586495-587373:-1
so has part: feature:586495-587373:-1:exon
subclass of: SO_0000010

853550
type: Gene
SIO_000068: ncbigene

position:586495:-1
position: 586495
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:587373:-1
position: 587373
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:586495-587373:-1:exon

YJR088C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: EMC2
locus tag: YJR088C
product: Emc2p
transcript id: NM_001181745.1
SIO_010081: YJR088C
subclass of: SO_0000673
so part of: YJR088C
location: complement(<586495..>587373)
location: region:586495-587373:-1
so has part: feature:586495-587373:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:586495-587373:-1:exon

YJR088C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: EMC2
locus tag: YJR088C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0072546 EMC complex [PMID:19325107]
experiment: EXISTENCE:genetic interaction:GO:0034975 protein folding in endoplasmic reticulum [PMID:19325107]
note: Member of conserved ER transmembrane complex; required for efficient folding of proteins in the ER; null mutant displays induction of the unfolded protein response; homologous to worm Y57G7A.10/EMC-2, fly CG17556, human TTC35
codon start: 1
product: Emc2p
translation: MLKDLVREKLLTIMNTKAYTQFNPEQLLQLENEMKIYMKSGDSALTEGNYFFLMEMLFYVLVYRNQDVDAQVVYNTLRDRLGENSYKMVIMKATLLQINGNDKGAIEYLENLLNDDLEYETDFVTYVSIAKKLIAIKTTSKNLSQESVLKEVVALTDKFPLDAELWWYASEIYFEMGQFEKACYCLEQVLCITPFNYACFGRLSETLYYEALRSKKQTKTELLEKALKNALRSVELSELYLKGWALVNIISRELGRNKQNDLIKLSASKLKEISAKSNNKDKITAELILNKI
SIO_010081: YJR088C
subclass of: SO_0000673
so part of: YJR088C
location: complement(586495..587373)
location: region:586495-587373:-1
so has part: feature:586495-587373:-1:exon

NP_012621.1
type: Protein
SIO_000068: ncbiprotein

S000003848
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:586495-587373:-1:exon

YJR089W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: BIR1
locus tag: YJR089W
so part of: sequence
location: <587718..>590582
location: region:587718-590582:1
so has part: feature:587718-590582:1:exon
subclass of: SO_0000010

853551
type: Gene
SIO_000068: ncbigene

position:587718:1
position: 587718
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:590582:1
position: 590582
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:587718-590582:1:exon

YJR089W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: BIR1
locus tag: YJR089W
product: survivin
transcript id: NM_001181746.3
SIO_010081: YJR089W
subclass of: SO_0000673
so part of: YJR089W
location: <587718..>590582
location: region:587718-590582:1
so has part: feature:587718-590582:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:587718-590582:1:exon

YJR089W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: BIR1
locus tag: YJR089W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:16608876]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:16608876]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005819 spindle [PMID:16381814]
experiment: EXISTENCE:direct assay:GO:0005874 microtubule [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0032133 chromosome passenger complex [PMID:19158380]
experiment: EXISTENCE:direct assay:GO:0051233 spindle midzone [PMID:16381814]
experiment: EXISTENCE:genetic interaction:GO:0000776 kinetochore [PMID:10557299]
experiment: EXISTENCE:mutant phenotype:GO:0000022 mitotic spindle elongation [PMID:16381814]
experiment: EXISTENCE:mutant phenotype:GO:0006915 apoptotic process [PMID:16608876]
experiment: EXISTENCE:mutant phenotype:GO:0007059 chromosome segregation [PMID:10557299]
experiment: EXISTENCE:mutant phenotype:GO:0007094 mitotic spindle assembly checkpoint signaling [PMID:22908045]
experiment: EXISTENCE:mutant phenotype:GO:0031134 sister chromatid biorientation [PMID:19528231]
note: Subunit of chromosomal passenger complex (CPC); CPC is comprised of Ipl1p-Sli15p-Bir1p-Nbl1p and regulates chromosome segregation; required for chromosome bi-orientation and for spindle assembly checkpoint activation upon reduced sister kinetochore tension; relative distribution to shortened microtubules increases upon DNA replication stress; sumoylated in an Mms21p-dependent manner; human survivin homolog
codon start: 1
product: survivin
translation: MDGQIDKMEKRYSMTKLENRLRTFQDGVALEKKKLKWSFKVIPYQAMAKLGFYFDPVIDPKTSKLKKDSVRCCYCHRQTYNVRDCRSKRKDVLETLSNIMRQHLTVTDNKQVCLLIYLRNKLLTDYSFHMGVSDWKNDKYFSNPDDENVINLRKFTFQDNWPHSGSQNEHPLGIEKMVNAGLMRYDSSIEGLGDPSMDKTLMNDTCYCIYCKQLLQGWSINDDPMSRHYKVSQNGNCYFFQTRNRFERIKNDNDSITKNCEVSPTLGENGKREVINTKTASQRQCPLFESPPSSTGPQLDDYNEKTDISVIQHNISVLDGAQGENVKRNSVEEKEQINMENGSTTLEEGNINRDVLADKKEVISTPTAKEIKRPNVQLTQSSSPIKKKRKFKRISPRKIFDEEDSEHSLNNNSANGDNKDKDLVIDFTSHIIKNRDVGRKNAILDDSTDEFSFSNQGHNTFDIPIPTSSHLLKGIDSDNDNVIREDDTGINTDTKGASSKHEKFSVNSEEDLNFSEVKLTGRDSSTNILIRTQIVDQNLGDIDRDKVPNGGSPEVPKTHELIRDNSEKREAQNGEFRHQKDSTVRQSPDILHSNKSGDNSSNITAIPKEEQRRGNSKTSSIPADIHPKPRKNLQEPRSLSISGKVVPTERKLDNINIDLNFSASDFSPSSQSEQSSKSSSVISTPVASPKINLTRSLHAVKELSGLKKETDDGKYFTNKQETIKILEDVSVKNETPNNEMLLFETGTPIASQENKSRKLFDEEFSGKELDIPIDSSTVEIKKVIKPEFEPVPSVARNLVSGTSSYPRNSRLEEQRKETSTSLADNSKKGSSFNEGNNEKEPNAAEWFKIDENRHLVKNYFHDLLKYINNNDATLANDKDGDLAFLIKQMPAEELDMTFNNWVNLKVQSIKREFIDDCDKKLDILRRDYYTATNFIETLEDDNQLIDIAKKMGIL
SIO_010081: YJR089W
subclass of: SO_0000673
so part of: YJR089W
location: 587718..590582
location: region:587718-590582:1
so has part: feature:587718-590582:1:exon

NP_012622.3
type: Protein
SIO_000068: ncbiprotein

S000003849
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:587718-590582:1:exon

YJR090C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CAT80
alternative label: COT2
alternative label: RMR3
alternative label: SDC1
alternative label: SSU2
gene: GRR1
locus tag: YJR090C
gene synonym: CAT80; COT2; RMR3; SDC1; SSU2
so part of: sequence
location: complement(<590872..>594327)
location: region:590872-594327:-1
so has part: feature:590872-594327:-1:exon
subclass of: SO_0000010

853552
type: Gene
SIO_000068: ncbigene

position:590872:-1
position: 590872
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:594327:-1
position: 594327
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:590872-594327:-1:exon

YJR090C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CAT80
alternative label: COT2
alternative label: RMR3
alternative label: SDC1
alternative label: SSU2
gene: GRR1
locus tag: YJR090C
gene synonym: CAT80; COT2; RMR3; SDC1; SSU2
product: SCF ubiquitin ligase complex subunit GRR1
transcript id: NM_001181747.1
SIO_010081: YJR090C
subclass of: SO_0000673
so part of: YJR090C
location: complement(<590872..>594327)
location: region:590872-594327:-1
so has part: feature:590872-594327:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:590872-594327:-1:exon

YJR090C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CAT80
alternative label: COT2
alternative label: RMR3
alternative label: SDC1
alternative label: SSU2
gene: GRR1
locus tag: YJR090C
gene synonym: CAT80; COT2; RMR3; SDC1; SSU2
experiment: EXISTENCE:direct assay:GO:0000142 cellular bud neck contractile ring [PMID:11080155|PMID:15775961]
experiment: EXISTENCE:direct assay:GO:0004842 ubiquitin-protein transferase activity [PMID:10213692]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:11080155]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11080155]
experiment: EXISTENCE:direct assay:GO:0030674 protein-macromolecule adaptor activity [PMID:11259599|PMID:9346238|PMID:9819356]
experiment: EXISTENCE:genetic interaction:GO:0000209 protein polyubiquitination [PMID:9499404]
experiment: EXISTENCE:mutant phenotype:GO:0000209 protein polyubiquitination [PMID:16093347]
experiment: EXISTENCE:mutant phenotype:GO:0000751 mitotic cell cycle G1 arrest in response to pheromone [PMID:15942932]
experiment: EXISTENCE:mutant phenotype:GO:0019005 SCF ubiquitin ligase complex [PMID:9736614]
experiment: EXISTENCE:mutant phenotype:GO:0030674 protein-macromolecule adaptor activity [PMID:9819356]
experiment: EXISTENCE:mutant phenotype:GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [PMID:29212878]
experiment: EXISTENCE:mutant phenotype:GO:0034599 cellular response to oxidative stress [PMID:29212878]
experiment: EXISTENCE:mutant phenotype:GO:0071406 cellular response to methylmercury [PMID:17141224]
experiment: EXISTENCE:physical interaction:GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [PMID:10213692]
note: F-box protein component of an SCF ubiquitin-ligase complex; modular substrate specificity factor which associates with core SCF (Cdc53p, Skp1p and Hrt1p/Rbx1p) to form the SCF(Grr1) complex; SCF(Grr1) acts as a ubiquitin-protein ligase directing ubiquitination of substrates such as: Gic2p, Mks1p, Mth1p, Cln1p, Cln2p and Cln3p; involved in carbon catabolite repression, glucose-dependent divalent cation transport, glucose transport, morphogenesis, and sulfite detoxification
codon start: 1
product: SCF ubiquitin ligase complex subunit GRR1
translation: MDQDNNNHNDSNRLHPPDIHPNLGPQLWLNSSGDFDDNNNNNNNNNNNNSTRPQMPSRTRETATSERNASEVRDATLNNIFRFDSIQRETLLPTNNGQPLNQNFSLTFQPQQQTNALNGIDINTVNTNLMNGVNVQIDQLNRLLPNLPEEERKQIHEFKLIVGKKIQEFLVVIEKRRKKILNEIELDNLKLKELRIDNSPQAISYLHKLQRMRLRALETENMEIRNLRLKILTIIEEYKKSLYAYCHSKLRGQQVENPTDNFIIWINSIDTTESSDLKEGLQDLSRYSRQFINNVLSNPSNQNICTSVTRRSPVFALNMLPSEILHLILDKLNQKYDIVKFLTVSKLWAEIIVKILYYRPHINKKSQLDLFLRTMKLTSEETVFNYRLMIKRLNFSFVGDYMHDTELNYFVGCKNLERLTLVFCKHITSVPISAVLRGCKFLQSVDITGIRDVSDDVFDTLATYCPRVQGFYVPQARNVTFDSLRNFIVHSPMLKRIKITANNNMNDELVELLANKCPLLVEVDITLSPNVTDSSLLKLLTRLVQLREFRITHNTNITDNLFQELSKVVDDMPSLRLIDLSGCENITDKTIESIVNLAPKLRNVFLGKCSRITDASLFQLSKLGKNLQTVHFGHCFNITDNGVRALFHSCTRIQYVDFACCTNLTNRTLYELADLPKLKRIGLVKCTQMTDEGLLNMVSLRGRNDTLERVHLSYCSNLTIYPIYELLMSCPRLSHLSLTAVPSFLRPDITMYCRPAPSDFSENQRQIFCVFSGKGVHKLRHYLVNLTSPAFGPHVDVNDVLTKYIRSKNLIFNGETLEDALRRIITDLNQDSAAIIAATGLNQINGLNNDFLFQNINFERIDEVFSWYLNTFDGIRMSSEEVNSLLLQVNKTFCEDPFSDVDDDQDYVVAPGVNREINSEMCHIVRKFHELNDHIDDFEVNVASLVRVQFQFTGFLLHEMTQTYMQMIELNRQICLVQKTVQESGNIDYQKGLLIWRLLFIDKFIMVVQKYKLSTVVLRLYLKDNITLLTRQRELLIAHQRSAWNNNNDNDANRNANNIVNIVSDAGANDTSNNETNNGNDDNETENPNFWRQFGNRMQISPDQMRNLQMGLRNQNMVRNNNNNTIDESMPDTAIDSQMDEASGTPDEDML
SIO_010081: YJR090C
subclass of: SO_0000673
so part of: YJR090C
location: complement(590872..594327)
location: region:590872-594327:-1
so has part: feature:590872-594327:-1:exon

NP_012623.1
type: Protein
SIO_000068: ncbiprotein

S000003850
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:590872-594327:-1:exon

YJR091C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PUF1
gene: JSN1
locus tag: YJR091C
gene synonym: PUF1
so part of: sequence
location: complement(<595061..>598336)
location: region:595061-598336:-1
so has part: feature:595061-598336:-1:exon
subclass of: SO_0000010

853553
type: Gene
SIO_000068: ncbigene

position:595061:-1
position: 595061
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:598336:-1
position: 598336
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:595061-598336:-1:exon

YJR091C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PUF1
gene: JSN1
locus tag: YJR091C
gene synonym: PUF1
product: Jsn1p
transcript id: NM_001181748.1
SIO_010081: YJR091C
subclass of: SO_0000673
so part of: YJR091C
location: complement(<595061..>598336)
location: region:595061-598336:-1
so has part: feature:595061-598336:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:595061-598336:-1:exon

YJR091C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PUF1
gene: JSN1
locus tag: YJR091C
gene synonym: PUF1
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:21685478|PMID:15024427|PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0009277 fungal-type cell wall [PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0032473 cytoplasmic side of mitochondrial outer membrane [PMID:16107558]
experiment: EXISTENCE:genetic interaction:GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [PMID:11101532]
experiment: EXISTENCE:mutant phenotype:GO:0031503 protein-containing complex localization [PMID:16107558]
experiment: EXISTENCE:mutant phenotype:GO:0051654 establishment of mitochondrion localization [PMID:16107558]
note: Member of the Puf family of RNA-binding proteins; interacts with mRNAs encoding membrane-associated proteins; involved in localizing the Arp2/3 complex to mitochondria; overexpression causes increased sensitivity to benomyl; JSN1 has a paralog, PUF2, that arose from the whole genome duplication
codon start: 1
product: Jsn1p
translation: MDKSKQMNINNLSNIPEVIDPGITIPIYEEEYENNGESNSQLQQQPQKLGSYRSRAGKFSNTLSNLLPSISAKLHHSKKNSHGKNGAEFSSSNNSSQSTVASKTPRASPSRSKMMESSIDGVTMDRPGSLTPPQDMEKLVHFPDSSNNFLIPAPRGSSDSFNLPHQISRTRNNTMSSQITSISSIAPKPRTSSGIWSSNASANDPMQQHLLQQLQPTTSNNTTNSNTLNDYSTKTAYFDNMVSTSGSQMADNKMNTNNLAIPNSVWSNTRQRSQSNASSIYTDAPLYEQPARASISSHYTIPTQESPLIADEIDPQSINWVTMDPTVPSINQISNLLPTNTISISNVFPLQHQQPQLNNAINLTSTSLATLCSKYGEVISARTLRNLNMALVEFSSVESAVKALDSLQGKEVSMIGAPSKISFAKILPMHQQPPQFLLNSQGLPLGLENNNLQPQPLLQEQLFNGAVTFQQQGNVSIPVFNQQSQQSQHQNHSSGSAGFSNVLHGYNNNNSMHGNNNNSANEKEQCPFPLPPPNVNEKEDLLREIIELFEANSDEYQINSLIKKSLNHKGTSDTQNFGPLPEPLSGREFDPPKLRELRKSIDSNAFSDLEIEQLAIAMLDELPELSSDYLGNTIVQKLFEHSSDIIKDIMLRKTSKYLTSMGVHKNGTWACQKMITMAHTPRQIMQVTQGVKDYCTPLINDQFGNYVIQCVLKFGFPWNQFIFESIIANFWVIVQNRYGARAVRACLEAHDIVTPEQSIVLSAMIVTYAEYLSTNSNGALLVTWFLDTSVLPNRHSILAPRLTKRIVELCGHRLASLTILKVLNYRGDDNARKIILDSLFGNVNAHDSSPPKELTKLLCETNYGPTFVHKVLAMPLLEDDLRAHIIKQVRKVLTDSTQIQPSRRLLEEVGLASPSSTHNKTKQQQQQHHNSSISHMFATPDTSGQHMRGLSVSSVKSGGSKHTTMNTTTTNGSSASTLSPGQPLNANSNSSMGYFSYPGVFPVSGFSGNASNGYAMNNDDLSSQFDMLNFNNGTRLSLPQLSLTNHNNTTMELVNNVGSSQPHTNNNNNNNNTNYNDDNTVFETLTLHSAN
SIO_010081: YJR091C
subclass of: SO_0000673
so part of: YJR091C
location: complement(595061..598336)
location: region:595061-598336:-1
so has part: feature:595061-598336:-1:exon

NP_012624.1
type: Protein
SIO_000068: ncbiprotein

S000003851
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:595061-598336:-1:exon

YJR092W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: BUD4
locus tag: YJR092W
so part of: sequence
location: <598735..>603078
location: region:598735-603078:1
so has part: feature:598735-603078:1:exon
subclass of: SO_0000010

853554
type: Gene
SIO_000068: ncbigene

position:598735:1
position: 598735
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:603078:1
position: 603078
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:598735-603078:1:exon

YJR092W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: BUD4
locus tag: YJR092W
product: Bud4p
transcript id: NM_001181749.3
SIO_010081: YJR092W
subclass of: SO_0000673
so part of: YJR092W
location: <598735..>603078
location: region:598735-603078:1
so has part: feature:598735-603078:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:598735-603078:1:exon

YJR092W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: BUD4
locus tag: YJR092W
experiment: EXISTENCE:direct assay:GO:0000142 cellular bud neck contractile ring [PMID:22553209]
experiment: EXISTENCE:direct assay:GO:0005525 GTP binding [PMID:22553209]
experiment: EXISTENCE:direct assay:GO:0005621 cellular bud scar [PMID:23345395]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:27385335|PMID:22842922]
experiment: EXISTENCE:mutant phenotype:GO:0005525 GTP binding [PMID:22553209]
experiment: EXISTENCE:mutant phenotype:GO:0007120 axial cellular bud site selection [PMID:22553209]
experiment: EXISTENCE:mutant phenotype:GO:0031106 septin ring organization [PMID:23345395]
experiment: EXISTENCE:mutant phenotype:GO:0097271 protein localization to bud neck [PMID:22553209]
note: Anillin-like protein involved in bud-site selection; required for the axial budding pattern; required for the formation and disassembly of the double septin ring structure, and generally for septin organization; functions as a platform linking the cytokinesis tag septins to the axial landmark through its multiple domains; in vivo substrate of Cdc28p/Clb2p
codon start: 1
product: Bud4p
translation: MHDAESTVDSLLKEIDNEMEQTKSNITQNGSEDTPHNWKLPLQEIGDDTMEMLVKHNTRSNATENSRGRSPSKMSTISNESLNLGLLRVNSELEESPAAVHQERIKNSVANGALGHANSPKVLNNLKNMAQDIDKLARDEEKPVKLSSSPLKFTLKSTQPLLSYPESPIHRSSIEIETNYDDEDEEEEDAYTCLTQSPQILHSPSRIPITNAVSINKLNLDFTLNPNESDKSLVSDTSVDSTGRELDTKTIPELPFCMSSTPEMTPVDEKCNLPSKLLNTSNNSHSDSRSPTASVEDLNISTNLPGADSSQNNPVTTDADALIENDVVRDLQQNMEHIDDAFDEKKVLDEGCSNEPVTFLGENDTRSIVYSNKGTNANVQEFSQEDSLAHSEPKFKDLNATSDDVWNEDKETDANISTSTKSEESYIADYKVTRQEDWDTKKLHQESEHANEQPAIIPQKDSSEETFTELNNESEFQRNFKDGEEYRIVQHEESLYGQRTKSPEENIINGSEIGVDHGEAAEVNEPLAKTSAEEHDLSSSCEDQSVSEARNKDRIEEKEVETKDENIETEKDESEYHKVEENEEPEHVPLLPPLPRWEEIQFNEPFIDENDTSNDSIDLTRSMKPSDYISIWHIQEEEIKSNSPESIANSQFSQQSSITTASTVDSKKDNGSTSFKFKPRIVSRSRIYNPKSRVSSLNYYDNEDYILSNSEWNALDPMRRNTLISKRIQDNIRTQKGHAPLIRPSIMKLNGEDSGFQNHFLEVEQPQEHENIPLSTHLSEQDITTNVGLDEQKLPTNTQDEAEISIREIESAGDITFNRGDLLSLSFDEELGQDFANFLDALDHDSTSFNHGPDDSSSFQRDSSKKSFNSLWESSYELKPPPSIRKQPIAPDVLQKLLESDTKDDADLEKIREERITEPRTGLGIGMLKTPVKDVSIALAASIKGYEASFSDTDSRPEGMNNSDAITLNMFDDFEEDKMTPSTPVRSISPIKRHVSSPFKVVKAGNKQENNEINIKAEEEIEPMTQQETDGLKQDIPPLLAQTKDNVEAKEETITQLEEPQDVEQEFPDMGTLYLSIKAISTLALYGTKSHRATYAIVFDNGENVVQTPWESLPYDGNIRINKEFELPIDFKGKAETSSASSERDSYKKCVITLKCKYEKPRHELVEIVDKVPVGKSFFGKTKYKFEKKYVQKKPKQDEWDYLFAQDGSFARCEIEINEEFLKNVAFNTSHMHYNMINKWSRIADKIHGSKRLYELPRKAPHKVASLDVEACFLERTSAFEQFPKQFSLVNKIVSKYKLQQNIYKEGYLLQDGGDLKGKIENRFFKLHGSQLSGYHEISRKAKIDINLLKVTKVLRNEDIQADNGGQRNFTDWVLFNECFQLVFDDGERITFNAECSNEEKSDWYNKLQEVVELNVFHQPWVKKYCEKLAEEEKTRTTGHNLKQDFN
SIO_010081: YJR092W
subclass of: SO_0000673
so part of: YJR092W
location: 598735..603078
location: region:598735-603078:1
so has part: feature:598735-603078:1:exon

NP_012625.5
type: Protein
SIO_000068: ncbiprotein

S000003852
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:598735-603078:1:exon

YJR093C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FIP1
locus tag: YJR093C
so part of: sequence
location: complement(<603220..>604203)
location: region:603220-604203:-1
so has part: feature:603220-604203:-1:exon
subclass of: SO_0000010

853555
type: Gene
SIO_000068: ncbigene

position:603220:-1
position: 603220
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:604203:-1
position: 604203
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:603220-604203:-1:exon

YJR093C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FIP1
locus tag: YJR093C
product: cleavage polyadenylation factor subunit FIP1
transcript id: NM_001181750.1
SIO_010081: YJR093C
subclass of: SO_0000673
so part of: YJR093C
location: complement(<603220..>604203)
location: region:603220-604203:-1
so has part: feature:603220-604203:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:603220-604203:-1:exon

YJR093C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FIP1
locus tag: YJR093C
experiment: EXISTENCE:direct assay:GO:0005847 mRNA cleavage and polyadenylation specificity factor complex [PMID:12819204]
experiment: EXISTENCE:direct assay:GO:0006378 mRNA polyadenylation [PMID:11344258]
experiment: EXISTENCE:direct assay:GO:0098789 pre-mRNA cleavage required for polyadenylation [PMID:11344258]
experiment: EXISTENCE:genetic interaction:GO:0030674 protein-macromolecule adaptor activity [PMID:21282348]
experiment: EXISTENCE:mutant phenotype:GO:0003723 RNA binding [PMID:11238938]
experiment: EXISTENCE:mutant phenotype:GO:0030674 protein-macromolecule adaptor activity [PMID:21282348]
experiment: EXISTENCE:physical interaction:GO:0030674 protein-macromolecule adaptor activity [PMID:7736590]
note: Subunit of cleavage polyadenylation factor (CPF); interacts directly with poly(A) polymerase (Pap1p) to regulate its activity; bridging factor that links Pap1p and the CPF complex via Yth1p
codon start: 1
product: cleavage polyadenylation factor subunit FIP1
translation: MSSSEDEDDKFLYGSDSELALPSSKRSRDDEADAGASSNPDIVKRQKFDSPVEETPATARDDRSDEDIYSDSSDDDSDSDLEVIISLGPDPTRLDAKLLDSYSTAATSSSKDVISVATDVSNTITKTSDERLITEGEANQGVTATTVKATESDGNVPKAMTGSIDLDKEGIFDSVGITTIDPEVLKEKPWRQPGANLSDYFNYGFNEFTWMEYLHRQEKLQQDYNPRRILMGLLSLQQQGKLNSANDTDSNLGNIIDNNNNVNNANMSNLNSNMGNSMSGTPNPPAPPMHPSFPPLPMFGSFPPFPMPGMMPPMNQQPNQNQNQNSK
SIO_010081: YJR093C
subclass of: SO_0000673
so part of: YJR093C
location: complement(603220..604203)
location: region:603220-604203:-1
so has part: feature:603220-604203:-1:exon

NP_012626.1
type: Protein
SIO_000068: ncbiprotein

S000003853
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:603220-604203:-1:exon

YJR094C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: IME1
locus tag: YJR094C
so part of: sequence
location: complement(<604569..>605651)
location: region:604569-605651:-1
so has part: feature:604569-605651:-1:exon
subclass of: SO_0000010

853556
type: Gene
SIO_000068: ncbigene

position:604569:-1
position: 604569
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:605651:-1
position: 605651
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:604569-605651:-1:exon

YJR094C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: IME1
locus tag: YJR094C
product: transcription factor IME1
transcript id: NM_001181751.1
SIO_010081: YJR094C
subclass of: SO_0000673
so part of: YJR094C
location: complement(<604569..>605651)
location: region:604569-605651:-1
so has part: feature:604569-605651:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:604569-605651:-1:exon

YJR094C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: IME1
locus tag: YJR094C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:8462841]
experiment: EXISTENCE:direct assay:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:29472539]
experiment: EXISTENCE:mutant phenotype:GO:0006357 regulation of transcription by RNA polymerase II [PMID:8205723]
experiment: EXISTENCE:mutant phenotype:GO:0007124 pseudohyphal growth [PMID:20876298]
experiment: EXISTENCE:mutant phenotype:GO:0040020 regulation of meiotic nuclear division [PMID:8205723]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:9660952]
experiment: EXISTENCE:physical interaction:GO:0008134 transcription factor binding [PMID:8628320]
note: Master regulator of meiosis that is active only during meiotic events; activates transcription of early meiotic genes through interaction with Ume6p; regulator of meiotic commitment; degraded by the 26S proteasome following phosphorylation by Ime2p; transcription is negatively regulated in cis by the IRT1 long noncoding antisense RNA
codon start: 1
product: transcription factor IME1
translation: MQADMHGKLHAALEDGFFLFPFEQQQQPNIYYDTTTDQEDRPCFSFGSTISPRSWHFEKSDKIASSQLQNLVHTQPIHLINPQILFNEEFLNLENIDSQPISKETKTTKDCTMATGPERGKKSSESTRSSSLSSLFSNDESASTFHSSFNNHDNFQKSNRNGDDIDISDTIKYETNTNAQKDIKIFQENFEFNEFPYTQDFYPYTTNYTYSKPTNIHESINSKNTDSYSQYQDQFPPHTDNIHSFNNRHYSNHKSTNCNYYNNTSNNNNASDNVYEADPFIDEPQVPSYYYPLEIAFDVEKSPPPSLQKLNSKELEFLKKLNSKLSRYAAAYSFSSSNDQDYYDKVRFQEISYKFSKTYS
SIO_010081: YJR094C
subclass of: SO_0000673
so part of: YJR094C
location: complement(604569..605651)
location: region:604569-605651:-1
so has part: feature:604569-605651:-1:exon

NP_012627.1
type: Protein
SIO_000068: ncbiprotein

S000003854
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:604569-605651:-1:exon

YNCJ0028C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: IRT1
locus tag: YNCJ0028C
so part of: sequence
location: complement(605936..607424)
location: region:605936-607424:-1
so has part: feature:605936-607424:-1:exon
subclass of: SO_0000011

23547381
type: Gene
SIO_000068: ncbigene

position:605936:-1
position: 605936
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:607424:-1
position: 607424
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:605936-607424:-1:exon

YNCJ0028C
type: Non Coding RNA
subclass of: SO_0000655
RO_0002162: 559292
nc RNA class: other
gene: IRT1
locus tag: YNCJ0028C
product: IRT1
note: Long noncoding RNA that governs mating-type control of gametogenesis; located in the IME1 promoter; in haploids, expression of IME1, the central inducer of gametogenesis, is inhibited in cis by transcription of IRT1, which recruits the Set2p histone methyltransferase and the Set3p histone deacetylase complex to establish repressive chromatin at the IME1 promoter
transcript id: NR_132197.1
SIO_010081: YNCJ0028C
subclass of: SO_0000673
so part of: YNCJ0028C
location: complement(605936..607424)
location: region:605936-607424:-1
so has part: feature:605936-607424:-1:exon

S000178119
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:605936-607424:-1:exon

YJR094W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RPL43B
locus tag: YJR094W-A
so part of: sequence
location: <608305..>608858
location: region:608305-608858:1
so has part: feature:608305-608858:1:exon
subclass of: SO_0000010

853557
type: Gene
SIO_000068: ncbigene

position:608305:1
position: 608305
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:608858:1
position: 608858
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:608305-608858:1:exon

YJR094W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RPL43B
locus tag: YJR094W-A
product: ribosomal 60S subunit protein L43B
transcript id: NM_001181752.3
SIO_010081: YJR094W-A
subclass of: SO_0000673
so part of: YJR094W-A
location: join(<608305..608306,608582..>608858)
location: region:608305-608858:1
so has part: feature:608305-608306:1:exon
so has part: feature:608582-608858:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:608305-608306:1:exon

position:608306:1
position: 608306
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:608582-608858:1:exon

position:608582:1
position: 608582
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YJR094W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RPL43B
locus tag: YJR094W-A
experiment: EXISTENCE:curator inference:GO:0002181 cytoplasmic translation [PMID:11983894]
experiment: EXISTENCE:curator inference:GO:0003735 structural constituent of ribosome [PMID:11983894]
experiment: EXISTENCE:direct assay:GO:0022625 cytosolic large ribosomal subunit [PMID:11983894]
note: Ribosomal 60S subunit protein L43B; homologous to mammalian ribosomal protein L37A, no bacterial homolog; RPL43B has a paralog, RPL43A, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress
codon start: 1
product: ribosomal 60S subunit protein L43B
translation: MAKRTKKVGITGKYGVRYGSSLRRQVKKLEIQQHARYDCSFCGKKTVKRGAAGIWTCSCCKKTVAGGAYTVSTAAAATVRSTIRRLREMVEA
SIO_010081: YJR094W-A
subclass of: SO_0000673
so part of: YJR094W-A
location: join(608305..608306,608582..608858)
location: region:608305-608858:1
so has part: feature:608305-608306:1:exon
so has part: feature:608582-608858:1:exon

NP_012628.3
type: Protein
SIO_000068: ncbiprotein

S000003855
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:608305-608306:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:608582-608858:1:exon

YJR095W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ACR1
gene: SFC1
locus tag: YJR095W
gene synonym: ACR1
so part of: sequence
location: <609773..>610741
location: region:609773-610741:1
so has part: feature:609773-610741:1:exon
subclass of: SO_0000010

853558
type: Gene
SIO_000068: ncbigene

position:609773:1
position: 609773
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:610741:1
position: 610741
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:609773-610741:1:exon

YJR095W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ACR1
gene: SFC1
locus tag: YJR095W
gene synonym: ACR1
product: Sfc1p
transcript id: NM_001181753.1
SIO_010081: YJR095W
subclass of: SO_0000673
so part of: YJR095W
location: <609773..>610741
location: region:609773-610741:1
so has part: feature:609773-610741:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:609773-610741:1:exon

YJR095W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ACR1
gene: SFC1
locus tag: YJR095W
gene synonym: ACR1
experiment: EXISTENCE:direct assay:GO:0005469 succinate:fumarate antiporter activity [PMID:9395087]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0015741 fumarate transport [PMID:9395087]
experiment: EXISTENCE:direct assay:GO:0015744 succinate transport [PMID:9395087]
note: Mitochondrial succinate-fumarate transporter; transports succinate into and fumarate out of the mitochondrion; required for ethanol and acetate utilization
codon start: 1
product: Sfc1p
translation: MSQKKKASHPAINLMAGGTAGLFEALCCHPLDTIKVRMQIYRRVAGIEHVKPPGFIKTGRTIYQKEGFLALYKGLGAVVIGIIPKMAIRFSSYEFYRTLLVNKESGIVSTGNTFVAGVGAGITEAVLVVNPMEVVKIRLQAQHLTPSEPNAGPKYNNAIHAAYTIVKEEGVSALYRGVSLTAARQATNQGANFTVYSKLKEFLQNYHQMDVLPSWETSCIGLISGAIGPFSNAPLDTIKTRLQKDKSISLEKQSGMKKIITIGAQLLKEEGFRALYKGITPRVMRVAPGQAVTFTVYEYVREHLENLGIFKKNDTPKPKPLK
SIO_010081: YJR095W
subclass of: SO_0000673
so part of: YJR095W
location: 609773..610741
location: region:609773-610741:1
so has part: feature:609773-610741:1:exon

NP_012629.1
type: Protein
SIO_000068: ncbiprotein

S000003856
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:609773-610741:1:exon

YJR096W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJR096W
so part of: sequence
location: <611195..>612043
location: region:611195-612043:1
so has part: feature:611195-612043:1:exon
subclass of: SO_0000010

853559
type: Gene
SIO_000068: ncbigene

position:611195:1
position: 611195
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:612043:1
position: 612043
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:611195-612043:1:exon

YJR096W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJR096W
product: aldo-keto reductase superfamily protein
transcript id: NM_001181754.1
SIO_010081: YJR096W
subclass of: SO_0000673
so part of: YJR096W
location: <611195..>612043
location: region:611195-612043:1
so has part: feature:611195-612043:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:611195-612043:1:exon

YJR096W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJR096W
experiment: EXISTENCE:direct assay:GO:0004032 alditol:NADP+ 1-oxidoreductase activity [PMID:11306085|PMID:12271459]
experiment: EXISTENCE:direct assay:GO:0004033 aldo-keto reductase (NADP) activity [PMID:17140678]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095|PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0019568 arabinose catabolic process [PMID:12271459]
experiment: EXISTENCE:genetic interaction:GO:0034599 cellular response to oxidative stress [PMID:17919749]
experiment: EXISTENCE:mutant phenotype:GO:0019568 arabinose catabolic process [PMID:12271459]
experiment: EXISTENCE:mutant phenotype:GO:0042843 D-xylose catabolic process [PMID:12271459]
note: Xylose and arabinose reductase; member of the aldo-keto reductase (AKR) family; GFP-fusion protein is induced in response to the DNA-damaging agent MMS
codon start: 1
product: aldo-keto reductase superfamily protein
translation: MVPKFYKLSNGFKIPSIALGTYDIPRSQTAEIVYEGVKCGYRHFDTAVLYGNEKEVGDGIIKWLNEDPGNHKREEIFYTTKLWNSQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSPLEGSKLRLETWRAMQEAVDEGLVKSIGVSNYGKKHIDELLNWPELKHKPVVNQIEISPWIMRQELADYCKSKGLVVEAFAPLCHGYKMTNPDLLKVCKEVDRNPGQVLIRWSLQHGYLPLPKTKTVKRLEGNLAAYNFELSDEQMKFLDHPDAYEPTDWECTDAP
SIO_010081: YJR096W
subclass of: SO_0000673
so part of: YJR096W
location: 611195..612043
location: region:611195-612043:1
so has part: feature:611195-612043:1:exon

NP_012630.1
type: Protein
SIO_000068: ncbiprotein

S000003857
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:611195-612043:1:exon

YJR097W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: DPH4
gene: JJJ3
locus tag: YJR097W
gene synonym: DPH4
so part of: sequence
location: <612413..>612931
location: region:612413-612931:1
so has part: feature:612413-612931:1:exon
subclass of: SO_0000010

853560
type: Gene
SIO_000068: ncbigene

position:612413:1
position: 612413
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:612931:1
position: 612931
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:612413-612931:1:exon

YJR097W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: DPH4
gene: JJJ3
locus tag: YJR097W
gene synonym: DPH4
product: Jjj3p
transcript id: NM_001181755.3
SIO_010081: YJR097W
subclass of: SO_0000673
so part of: YJR097W
location: <612413..>612931
location: region:612413-612931:1
so has part: feature:612413-612931:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:612413-612931:1:exon

YJR097W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: DPH4
gene: JJJ3
locus tag: YJR097W
gene synonym: DPH4
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0008198 ferrous iron binding [PMID:22367199]
experiment: EXISTENCE:mutant phenotype:GO:0017183 peptidyl-diphthamide biosynthetic process from peptidyl-histidine [PMID:15485916]
note: Iron-binding protein; involved in targeting cytoplasmic SRP-independent proteins to the ER; contains a CSL Zn finger and a DnaJ-domain; involved in diphthamide biosynthesis; ortholog human Dph4
codon start: 1
product: Jjj3p
translation: MSLVNSLTHYEILRIPSDATQDEIKKAYRNRLLNTHPDKLSKSIHDTVSNVTINKIQDAYKILSNIKTRREYDRLILENYKRQGFHNCGDGLDEFSLDDFSFDEDKLEFMMNCPRCQFVGGFHFSESLLDECIDNVDAMERSHSGYQLLTQCSACSLWLKVNFDIEEEQEGQ
SIO_010081: YJR097W
subclass of: SO_0000673
so part of: YJR097W
location: 612413..612931
location: region:612413-612931:1
so has part: feature:612413-612931:1:exon

NP_012631.3
type: Protein
SIO_000068: ncbiprotein

S000003858
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:612413-612931:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS1019; Autonomously Replicating Sequence
so part of: sequence
location: 612846..613278
location: region:612846-613278:1
so has part: feature:612846-613278:1:region

S000028456
type: SGD
SIO_000068: sgd

position:612846:1
position: 612846
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:613278:1
position: 613278
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:612846-613278:1:region

YJR098C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJR098C
so part of: sequence
location: complement(<613186..>615156)
location: region:613186-615156:-1
so has part: feature:613186-615156:-1:exon
subclass of: SO_0000010

853561
type: Gene
SIO_000068: ncbigene

position:613186:-1
position: 613186
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:615156:-1
position: 615156
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:613186-615156:-1:exon

YJR098C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJR098C
product: uncharacterized protein
transcript id: NM_001181756.2
SIO_010081: YJR098C
subclass of: SO_0000673
so part of: YJR098C
location: complement(<613186..>615156)
location: region:613186-615156:-1
so has part: feature:613186-615156:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:613186-615156:-1:exon

YJR098C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJR098C
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
note: hypothetical protein; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
codon start: 1
product: uncharacterized protein
translation: MMATPATDLISDNDKYNKQCLSDSSDSGSDVSFFSVNESEGELDTMEKVDTLIGGARVISNKVEKDSDSEQRGRKKETTGPNNYHNLEEKQASAISLDADDEDLDEIISYSHDGNYDSSHKTFSFSLPFGNTNFRSSSPLAIIKTVLPKTPDEFIKKNLRKNEIKQKLKKSTSISSLEEIELFKYERGIDNSRLRAVKESLEMDALKNSIKQITADPFDKTHDGYYRSRLESIWNELEGDVVIMGGYRGSVLRDATTHKRIWIPLKAGLNMTKVDLLIGPNDEDELKTQKEIVPDGMLTHIGPVDISKRLIKRLDANPNLNVQQFGYDWRLSLDISAKHLTTKLEEIYNKQKNKKGIYIIAHSMGGLVAHKVLQDCTHLIRGIIYVGSPSQCPNILGPIRFGDDVMWNKTIFTKETNFFMRSSFYFLPLDGRCFVDKITLERYDFDFFDTDVWKTLGLSPLVNEKREESAHEKSKLLPRKTKSALSLKATLNATTKFVLNAPVVRNVAGNNKQVPRDVPFDEVFHTSYEDSCEYLARTLKRTKNYLDSLDYDPNKEYPPLAMVYGNKVPTVRGAKVNGIQDIKDGNYEDFYYGPGDGVVHHKWLLPEQRGFPVVCKIASSSGHVSLMTDLKSMAKAFISIVDSEKEGRRSRTRTSS
SIO_010081: YJR098C
subclass of: SO_0000673
so part of: YJR098C
location: complement(613186..615156)
location: region:613186-615156:-1
so has part: feature:613186-615156:-1:exon

NP_012632.2
type: Protein
SIO_000068: ncbiprotein

S000003859
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:613186-615156:-1:exon

YJR099W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: YUH1
locus tag: YJR099W
so part of: sequence
location: <615576..>616286
location: region:615576-616286:1
so has part: feature:615576-616286:1:exon
subclass of: SO_0000010

853562
type: Gene
SIO_000068: ncbigene

position:615576:1
position: 615576
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:616286:1
position: 616286
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:615576-616286:1:exon

YJR099W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: YUH1
locus tag: YJR099W
product: ubiquitin-specific protease YUH1
transcript id: NM_001181757.1
SIO_010081: YJR099W
subclass of: SO_0000673
so part of: YJR099W
location: <615576..>616286
location: region:615576-616286:1
so has part: feature:615576-616286:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:615576-616286:1:exon

YJR099W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: YUH1
locus tag: YJR099W
EC number: 3.4.19.12
experiment: EXISTENCE:curator inference:GO:0005737 cytoplasm [PMID:1429680]
experiment: EXISTENCE:curator inference:GO:0010992 ubiquitin recycling [PMID:1429680]
experiment: EXISTENCE:direct assay:GO:0004843 cysteine-type deubiquitinase activity [PMID:1429680]
note: Ubiquitin C-terminal hydrolase; cleaves ubiquitin-protein fusions to generate monomeric ubiquitin; hydrolyzes the peptide bond at the C-terminus of ubiquitin; also the major processing enzyme for the ubiquitin-like protein Rub1p
codon start: 1
product: ubiquitin-specific protease YUH1
translation: MSGENRAVVPIESNPEVFTNFAHKLGLKNEWAYFDIYSLTEPELLAFLPRPVKAIVLLFPINEDRKSSTSQQITSSYDVIWFKQSVKNACGLYAILHSLSNNQSLLEPGSDLDNFLKSQSDTSSSKNRFDDVTTDQFVLNVIKENVQTFSTGQSEAPEATADTNLHYITYVEENGGIFELDGRNLSGPLYLGKSDPTATDLIEQELVRVRVASYMENANEEDVLNFAMLGLGPNWE
SIO_010081: YJR099W
subclass of: SO_0000673
so part of: YJR099W
location: 615576..616286
location: region:615576-616286:1
so has part: feature:615576-616286:1:exon

NP_012633.1
type: Protein
SIO_000068: ncbiprotein

S000003860
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:615576-616286:1:exon

YJR100C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SLM35
gene: AIM25
locus tag: YJR100C
gene synonym: SLM35
so part of: sequence
location: complement(<616351..>617334)
location: region:616351-617334:-1
so has part: feature:616351-617334:-1:exon
subclass of: SO_0000010

853563
type: Gene
SIO_000068: ncbigene

position:616351:-1
position: 616351
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:617334:-1
position: 617334
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:616351-617334:-1:exon

YJR100C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SLM35
gene: AIM25
locus tag: YJR100C
gene synonym: SLM35
product: Aim25p
transcript id: NM_001181758.3
SIO_010081: YJR100C
subclass of: SO_0000673
so part of: YJR100C
location: complement(<616351..>617334)
location: region:616351-617334:-1
so has part: feature:616351-617334:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:616351-617334:-1:exon

YJR100C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SLM35
gene: AIM25
locus tag: YJR100C
gene synonym: SLM35
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:genetic interaction:GO:0034599 cellular response to oxidative stress [PMID:27922823]
experiment: EXISTENCE:genetic interaction:GO:0034605 cellular response to heat [PMID:27922823]
experiment: EXISTENCE:mutant phenotype:GO:0034599 cellular response to oxidative stress [PMID:27922823]
experiment: EXISTENCE:mutant phenotype:GO:1903147 negative regulation of autophagy of mitochondrion [PMID:27922823]
note: Mitochondria hypothetical protein; interacts genetically with TOR1 to regulate chronological lifespan, and the response to both heat shock and oxidative stress; involved in maintaining the integrity of the mitochondrial network; negative regulator of mitophagy flux; non-tagged protein is detected in purified mitochondria in high-throughput studies; null mutant is viable and displays an elevated frequency of mitochondrial genome loss; similar to murine NOR1
codon start: 1
product: Aim25p
translation: MHRTAIFLTYRSCMRNFSTLSKTLTVSSGKVIRNGPFRRVIREKNQITKAPSVKAFKENSNSGIIKVHDPIATTILNEPTVIIERQIEFMNVFLGFEQANRYAIMDVNGNKIASMMERDFSITKAIMRQFYRLHRPFLVDVFDNWGNVIMTIKRPFSFINSHIKTIIPPSAYVDNGSDSTHYHDGKEGTTVGETIQNWHLWRRRYELFQKDGVEGSTFDQFGKIDAPFLSFDFPVTDADGKIMASVDRNWVGLGREMFTDTGVYVVRFDSQRCFDNIYPTEMLSSQVLTLDQRAVLLANAVSIDFDYFSRHSRQTGGFLSFGGGYDE
SIO_010081: YJR100C
subclass of: SO_0000673
so part of: YJR100C
location: complement(616351..617334)
location: region:616351-617334:-1
so has part: feature:616351-617334:-1:exon

NP_012634.3
type: Protein
SIO_000068: ncbiprotein

S000003861
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:616351-617334:-1:exon

YNCJ0029W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCJ0029W
so part of: sequence
location: 617919..618019
location: region:617919-618019:1
so has part: feature:617919-618019:1:exon
subclass of: SO_0000663

853564
type: Gene
SIO_000068: ncbigene

position:617919:1
position: 617919
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:618019:1
position: 618019
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:617919-618019:1:exon

YNCJ0029W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCJ0029W
product: tRNA-Leu
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Leucine tRNA (tRNA-Leu), predicted by tRNAscan-SE analysis
SIO_010081: YNCJ0029W
subclass of: SO_0000673
so part of: YNCJ0029W
location: join(617919..617956,617976..618019)
location: region:617919-618019:1
so has part: feature:617919-617956:1:exon
so has part: feature:617976-618019:1:exon

S000006654
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:617919-617956:1:exon

position:617956:1
position: 617956
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:617976-618019:1:exon

position:617976:1
position: 617976
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YJR101W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: mS42
gene: RSM26
locus tag: YJR101W
gene synonym: mS42
so part of: sequence
location: <618234..>619034
location: region:618234-619034:1
so has part: feature:618234-619034:1:exon
subclass of: SO_0000010

853565
type: Gene
SIO_000068: ncbigene

position:618234:1
position: 618234
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:619034:1
position: 619034
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:618234-619034:1:exon

YJR101W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: mS42
gene: RSM26
locus tag: YJR101W
gene synonym: mS42
product: mitochondrial 37S ribosomal protein RSM26
transcript id: NM_001181759.1
SIO_010081: YJR101W
subclass of: SO_0000673
so part of: YJR101W
location: <618234..>619034
location: region:618234-619034:1
so has part: feature:618234-619034:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:618234-619034:1:exon

YJR101W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: mS42
gene: RSM26
locus tag: YJR101W
gene synonym: mS42
experiment: EXISTENCE:curator inference:GO:0032543 mitochondrial translation [PMID:11278769]
experiment: EXISTENCE:direct assay:GO:0003735 structural constituent of ribosome [PMID:11278769]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005763 mitochondrial small ribosomal subunit [PMID:11278769]
note: Mitochondrial ribosomal protein of the small subunit
codon start: 1
product: mitochondrial 37S ribosomal protein RSM26
translation: MLVFKRGIHVVPKLPNSKALLQNGVPNILSSSGFKTVWFDYQRYLCDKLTLATAGQSLESYYPFHILLKTAGNPLQSNIFNLASSIHNNHLFVENILPSAVEHGTNSNAVVKTEPSRLFLSKIKDSFNGSDWEVVKEEMIYRAENEVLGQGWLFLVENNEKKLFILTSNNNGTPYYFPRNQSFDLNSAISIDEFATLKQMKELIGKSTKLNGKVQDWTMPIICVNLWDHAYLHDYGVGNRSKYVKNVLDNLNWSVVNNRIFSGISK
SIO_010081: YJR101W
subclass of: SO_0000673
so part of: YJR101W
location: 618234..619034
location: region:618234-619034:1
so has part: feature:618234-619034:1:exon

NP_012635.1
type: Protein
SIO_000068: ncbiprotein

S000003862
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:618234-619034:1:exon

YJR102C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: VPL12
alternative label: VPT25
gene: VPS25
locus tag: YJR102C
gene synonym: VPL12; VPT25
so part of: sequence
location: complement(<619157..>619765)
location: region:619157-619765:-1
so has part: feature:619157-619765:-1:exon
subclass of: SO_0000010

853566
type: Gene
SIO_000068: ncbigene

position:619157:-1
position: 619157
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:619765:-1
position: 619765
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:619157-619765:-1:exon

YJR102C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: VPL12
alternative label: VPT25
gene: VPS25
locus tag: YJR102C
gene synonym: VPL12; VPT25
product: ESCRT-II subunit protein VPS25
transcript id: NM_001181760.1
SIO_010081: YJR102C
subclass of: SO_0000673
so part of: YJR102C
location: complement(<619157..>619765)
location: region:619157-619765:-1
so has part: feature:619157-619765:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:619157-619765:-1:exon

YJR102C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: VPL12
alternative label: VPT25
gene: VPS25
locus tag: YJR102C
gene synonym: VPL12; VPT25
experiment: EXISTENCE:curator inference:GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [PMID:15086794]
experiment: EXISTENCE:direct assay:GO:0000814 ESCRT II complex [PMID:12194858]
experiment: EXISTENCE:direct assay:GO:0005198 structural molecule activity [PMID:15329733|PMID:15469844]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0000433 carbon catabolite repression of transcription from RNA polymerase II promoter by glucose [PMID:11278625]
experiment: EXISTENCE:mutant phenotype:GO:0005198 structural molecule activity [PMID:15329733|PMID:15469844]
experiment: EXISTENCE:mutant phenotype:GO:0006623 protein targeting to vacuole [PMID:12194858]
experiment: EXISTENCE:mutant phenotype:GO:1904669 ATP export [PMID:26585826]
note: Component of the ESCRT-II complex; ESCRT-II is involved in ubiquitin-dependent sorting of proteins into the endosome
codon start: 1
product: ESCRT-II subunit protein VPS25
translation: MSALPPVYSFPPLYTRQPNSLTRRQQISTWIDIISQYCKTKKIWYMSVDGTVINDNELDSGSTDNDDSKKISKNLFNNEDIQRSVSQVFIDEIWSQMTKEGKCLPIDQSGRRSSNTTTTRYFILWKSLDSWASLILQWFEDSGKLNQVITLYELSEGDETVNWEFHRMPESLLYYCLKPLCDRNRATMLKDENDKVIAIKVV
SIO_010081: YJR102C
subclass of: SO_0000673
so part of: YJR102C
location: complement(619157..619765)
location: region:619157-619765:-1
so has part: feature:619157-619765:-1:exon

NP_012636.1
type: Protein
SIO_000068: ncbiprotein

S000003863
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:619157-619765:-1:exon

YJR103W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: URA8
locus tag: YJR103W
so part of: sequence
location: <620754..>622490
location: region:620754-622490:1
so has part: feature:620754-622490:1:exon
subclass of: SO_0000010

853567
type: Gene
SIO_000068: ncbigene

position:620754:1
position: 620754
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:622490:1
position: 622490
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:620754-622490:1:exon

YJR103W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: URA8
locus tag: YJR103W
product: CTP synthase URA8
transcript id: NM_001181761.4
SIO_010081: YJR103W
subclass of: SO_0000673
so part of: YJR103W
location: <620754..>622490
location: region:620754-622490:1
so has part: feature:620754-622490:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:620754-622490:1:exon

YJR103W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: URA8
locus tag: YJR103W
EC number: 6.3.4.2
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0003883 CTP synthase activity [PMID:7559626]
experiment: EXISTENCE:direct assay:GO:0006241 CTP biosynthetic process [PMID:7559626]
experiment: EXISTENCE:direct assay:GO:0097268 cytoophidium [PMID:20713603]
experiment: EXISTENCE:mutant phenotype:GO:0003883 CTP synthase activity [PMID:8121398]
note: Minor CTP synthase isozyme (see also URA7); catalyzes the ATP-dependent transfer of the amide nitrogen from glutamine to UTP, forming CTP, the final step in de novo biosynthesis of pyrimidines; involved in phospholipid biosynthesis; capable of forming cytoplasmic filaments termed cytoophidium, especially during conditions of glucose depletion; URA8 has a paralog, URA7, that arose from the whole genome duplication
codon start: 1
product: CTP synthase URA8
translation: MKYVVVSGGVISGIGKGVLASSTGMLLKTLGLKVTSIKIDPYMNIDAGTMSPLEHGECFVLDDGGETDLDLGNYERYLGITLSRDHNITTGKIYSHVISRERRGDYLGKTVQIVPHLTNAIQDWIQRVSKIPVDDTGLEPDVCIIELGGTVGDIESAPFVEALRQFQFEVGRENFALIHVSLVPVIHGEQKTKPTQAAIKDLRSLGLIPDMIACRCSEELNRSTIDKIAMFCHVGPEQVVNVHDVNSTYHVPLLLLKQHMIDYLHSRLKLGEVPLTLEDKERGSQLLTNWENMTKNLDDSDDVVKIALVGKYTNLKDSYLSVTKSLEHASMKCRRQLEILWVEASNLEPETQEVDKNKFHDSWNKLSSADGILVPGGFGTRGIEGMILAAKWARESGVPFLGVCLGLQVAAIEFARNVIGRPNSSSTEFLDETLLAPEDQVVIYMPEIDKEHMGGTMRLGLRPTIFQPNSEWSNIRKLYGEVNEVHERHRHRYEINPKIVNDMESRGFIFVGKDETGQRCEIFELKGHPYYVGTQYHPEYTSKVLEPSRPFWGLVAAASGTLGEVIKDINLSEGNENE
SIO_010081: YJR103W
subclass of: SO_0000673
so part of: YJR103W
location: 620754..622490
location: region:620754-622490:1
so has part: feature:620754-622490:1:exon

NP_012637.4
type: Protein
SIO_000068: ncbiprotein

S000003864
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:620754-622490:1:exon

YJR104C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CRS4
gene: SOD1
locus tag: YJR104C
gene synonym: CRS4
so part of: sequence
location: complement(<622550..>623014)
location: region:622550-623014:-1
so has part: feature:622550-623014:-1:exon
subclass of: SO_0000010

853568
type: Gene
SIO_000068: ncbigene

position:622550:-1
position: 622550
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:623014:-1
position: 623014
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:622550-623014:-1:exon

YJR104C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CRS4
gene: SOD1
locus tag: YJR104C
gene synonym: CRS4
product: superoxide dismutase SOD1
transcript id: NM_001181762.1
SIO_010081: YJR104C
subclass of: SO_0000673
so part of: YJR104C
location: complement(<622550..>623014)
location: region:622550-623014:-1
so has part: feature:622550-623014:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:622550-623014:-1:exon

YJR104C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CRS4
gene: SOD1
locus tag: YJR104C
gene synonym: CRS4
EC number: 1.15.1.1
experiment: EXISTENCE:direct assay:GO:0004784 superoxide dismutase activity [PMID:3290902]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:18977757|PMID:24647101]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005758 mitochondrial intermembrane space [PMID:11500508]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:11500508]
experiment: EXISTENCE:mutant phenotype:GO:0006801 superoxide metabolic process [PMID:3290902]
experiment: EXISTENCE:mutant phenotype:GO:0006878 cellular copper ion homeostasis [PMID:8530401]
experiment: EXISTENCE:mutant phenotype:GO:0006882 cellular zinc ion homeostasis [PMID:11581253]
experiment: EXISTENCE:mutant phenotype:GO:0031505 fungal-type cell wall organization [PMID:20176017]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:24647101]
experiment: EXISTENCE:mutant phenotype:GO:0050821 protein stabilization [PMID:23332757]
experiment: EXISTENCE:mutant phenotype:GO:0051091 positive regulation of DNA-binding transcription factor activity [PMID:18977757]
experiment: EXISTENCE:mutant phenotype:GO:1901856 negative regulation of cellular respiration [PMID:23332757]
experiment: EXISTENCE:physical interaction:GO:0050821 protein stabilization [PMID:23332757]
note: Cytosolic copper-zinc superoxide dismutase; detoxifies superoxide; stabilizes Yck1p and Yck2p kinases in glucose to repress respiration; phosphorylated by Dun1p, enters nucleus under oxidative stress to promote transcription of stress response genes; human ortholog SOD1 implicated in ALS complements a null allele; abundance increases under DNA replication stress and during exposure to boric acid; localization to mitochondrial intermembrane space is modulated by MICOS complex
codon start: 1
product: superoxide dismutase SOD1
translation: MVQAVAVLKGDAGVSGVVKFEQASESEPTTVSYEIAGNSPNAERGFHIHEFGDATNGCVSAGPHFNPFKKTHGAPTDEVRHVGDMGNVKTDENGVAKGSFKDSLIKLIGPTSVVGRSVVIHAGQDDLGKGDTEESLKTGNAGPRPACGVIGLTN
SIO_010081: YJR104C
subclass of: SO_0000673
so part of: YJR104C
location: complement(622550..623014)
location: region:622550-623014:-1
so has part: feature:622550-623014:-1:exon

NP_012638.1
type: Protein
SIO_000068: ncbiprotein

S000003865
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:622550-623014:-1:exon

YJR105W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ADO1
locus tag: YJR105W
so part of: sequence
location: <623581..>624603
location: region:623581-624603:1
so has part: feature:623581-624603:1:exon
subclass of: SO_0000010

853569
type: Gene
SIO_000068: ncbigene

position:623581:1
position: 623581
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:624603:1
position: 624603
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:623581-624603:1:exon

YJR105W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ADO1
locus tag: YJR105W
product: adenosine kinase
transcript id: NM_001181763.1
SIO_010081: YJR105W
subclass of: SO_0000673
so part of: YJR105W
location: <623581..>624603
location: region:623581-624603:1
so has part: feature:623581-624603:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:623581-624603:1:exon

YJR105W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ADO1
locus tag: YJR105W
EC number: 2.7.1.20
experiment: EXISTENCE:direct assay:GO:0004001 adenosine kinase activity [PMID:11223943]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0004001 adenosine kinase activity [PMID:11223943]
experiment: EXISTENCE:mutant phenotype:GO:0006144 purine nucleobase metabolic process [PMID:11223943]
note: Adenosine kinase; required for the utilization of S-adenosylmethionine (AdoMet); may be involved in recycling adenosine produced through the methyl cycle
codon start: 1
product: adenosine kinase
translation: MTAPLVVLGNPLLDFQADVTAEYLAKYSLKENDAILVDAKSGDAKMAIFDELLQMPETKLVAGGAAQNTARGAAYVLGAGQVVYFGSVGKDKFSERLLNENEKAGVKSMYQVQNDIGTGKCAALITGHNRSLVTDLGAANFFTPDHLDKHWDLVEAAKLFYIGGFHLTVSPDAIVKLGQHAKENSKPFVLNFSAPFIPHVFKDALARVLPYATVIIANESEAEAFCDAFQLDCANTDLEAIAQRIVKDSPVEKTVIFTHGVEPTVVVSSKGTSTYPVKPLDSSKIVDTNGAGDAFAGGFMAGLTKGEDLETSIDMGQWLAALSIQEVGPSYPSEKISYSK
SIO_010081: YJR105W
subclass of: SO_0000673
so part of: YJR105W
location: 623581..624603
location: region:623581-624603:1
so has part: feature:623581-624603:1:exon

NP_012639.1
type: Protein
SIO_000068: ncbiprotein

S000003866
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:623581-624603:1:exon

YJR106W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ECM27
locus tag: YJR106W
so part of: sequence
location: <624838..>627015
location: region:624838-627015:1
so has part: feature:624838-627015:1:exon
subclass of: SO_0000010

853570
type: Gene
SIO_000068: ncbigene

position:624838:1
position: 624838
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:627015:1
position: 627015
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:624838-627015:1:exon

YJR106W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ECM27
locus tag: YJR106W
product: Ecm27p
transcript id: NM_001181764.4
SIO_010081: YJR106W
subclass of: SO_0000673
so part of: YJR106W
location: <624838..>627015
location: region:624838-627015:1
so has part: feature:624838-627015:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:624838-627015:1:exon

YJR106W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ECM27
locus tag: YJR106W
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0006874 cellular calcium ion homeostasis [PMID:27242146]
experiment: EXISTENCE:mutant phenotype:GO:0070316 regulation of G0 to G1 transition [PMID:27242146]
note: Protein involved in calcium homeostasis and exit from quiescence; required for proper trehalose levels during quiescence; may play a role in cell wall biosynthesis, mutants are hypersensitive to antifungal, Papulacandin B; null mutants have increased plasmid loss; interacts with Pdr5p
codon start: 1
product: Ecm27p
translation: MDWAINVAHPRLLYKDPKLSVTFIVPSLFHIIIAFVLLGICASDFLCPNVAHISDPNSLRSNGSLVSKTASHASHTGALMAVLLSWCNSSPDLFSNLMSWATSTRETRSTSVSLSIGEVLGACGIILCIVEGSIFIIMSRTHIEISQIQKLSIMRDLLFSLAAMCVMSYVSLMNQVTVLNCLLMAFLYAFYLVVKLTFKLNHSAETPDETAADTSLRENSVSPFLDDSLMASGLLPPIQPGFDISNSITHGIKPSLLSAMDFNSFLSMLENSSLEEDDSRNEMAELNTLRSMTPGQHWSASATVAGEATSAGRPFSEPTNAFTEYRDSERAINSSPAVFAPYRDNPDDEESQEQVLLETTTHGHFGAQEMRRFSKRSLGWIIKIFIPHLSNFSQKSISDAIFSIITVPFFIIFKLSCPQPPSDILSYDPTLNRYSLTTLPIILLFIQSITAPFLLCSILSVLLTYHLGYLVYLFPLILAMALILLLTAFITKVNLHNKFTLSLDSSNILQEKLQKRKLLERLNTSIQIIFLAIGIINIIIWISLLANSLIEMMEIYQKILGLSKAILGLTIFAWGNSVGDLISNISMCRLYKTQTHYQDRVRLATKFFMISCASCLGGVMLNSMGGIGFSGLVSMLFIGAFNDNEWWFLRKVKLQETSQLDNTLNYKFIVSCVFIILQIILLLLFFGGPNNIKRRLTKEMKLVGISMCGLWALATLINILLELFS
SIO_010081: YJR106W
subclass of: SO_0000673
so part of: YJR106W
location: 624838..627015
location: region:624838-627015:1
so has part: feature:624838-627015:1:exon

NP_012640.4
type: Protein
SIO_000068: ncbiprotein

S000003867
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:624838-627015:1:exon

YJR107W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: LIH1
locus tag: YJR107W
so part of: sequence
location: <627340..>628326
location: region:627340-628326:1
so has part: feature:627340-628326:1:exon
subclass of: SO_0000010

853571
type: Gene
SIO_000068: ncbigene

position:627340:1
position: 627340
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:628326:1
position: 628326
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:627340-628326:1:exon

YJR107W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: LIH1
locus tag: YJR107W
product: putative lipase
transcript id: NM_001181765.2
SIO_010081: YJR107W
subclass of: SO_0000673
so part of: YJR107W
location: <627340..>628326
location: region:627340-628326:1
so has part: feature:627340-628326:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:627340-628326:1:exon

YJR107W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: LIH1
locus tag: YJR107W
EC number: 3.1.1.3
note: Putative lipase
codon start: 1
product: putative lipase
translation: MPVVHCSSNLPITPYIYERLVYFIKASSISSCISDNLLLVNKTFNDGGCPPHINFCNDEIINPTAGQTVVELVLNAKKGELGSGYLAVDHGKKVVILAFRGSTTRQDWFSDFEIYPVNYSPLCVKEYRKLIEEGKIRECEGCKMHRGFLRFTETLGMDVFKKMESILESFPEYRIVVTGHSLGAALASLAGIELKIRGFDPLVLTFATPKIFNSEMKQWVDELFETDAIEKESILKDEIQFRKGYFRVVHTGDYIPMVPPFYHPAGLEMFINKVGLPQNAEDIEYRGKNNRLTLKDGFREGMSGLVEDWLHVYEHRAYFIDVVGCSGL
SIO_010081: YJR107W
subclass of: SO_0000673
so part of: YJR107W
location: 627340..628326
location: region:627340-628326:1
so has part: feature:627340-628326:1:exon

NP_012641.2
type: Protein
SIO_000068: ncbiprotein

S000003868
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:627340-628326:1:exon

YJR107C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJR107C-A
so part of: sequence
location: complement(<628457..>628693)
location: region:628457-628693:-1
so has part: feature:628457-628693:-1:exon
subclass of: SO_0000010

65052910
type: Gene
SIO_000068: ncbigene

position:628457:-1
position: 628457
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:628693:-1
position: 628693
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:628457-628693:-1:exon

YJR107C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJR107C-A
product: uncharacterized protein
transcript id: NM_001395036.1
SIO_010081: YJR107C-A
subclass of: SO_0000673
so part of: YJR107C-A
location: complement(<628457..>628693)
location: region:628457-628693:-1
so has part: feature:628457-628693:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:628457-628693:-1:exon

YJR107C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJR107C-A
experiment: EXISTENCE:mutant phenotype:GO:0071470 cellular response to osmotic stress [PMID:26554900]
note: hypothetical protein; encodes new type of domain, which ab initio modeling suggests is predominantly alpha-helical; nonessential for growth, deletion increases sensitivity to osmostress; expressed at moderate to high abundance; ORF also present in strains EC1118, YJM789, RM11-1a, and AWRI1631; Gln24 in S288C reference is substituted with Arg in wine strain EC1118; predicted S-palmitoylation site on Cys2, suggesting membrane association; transcript previously mischaracterized as SUT646
codon start: 1
product: uncharacterized protein
translation: MCDDSYDAVEEYYFNKSVAGISGQENWNKQLATQVYSRSLQPEILPTLKPLSCNKERANAGKRVSEEEQINGKRKRKD
SIO_010081: YJR107C-A
subclass of: SO_0000673
so part of: YJR107C-A
location: complement(628457..628693)
location: region:628457-628693:-1
so has part: feature:628457-628693:-1:exon

NP_001381966.1
type: Protein
SIO_000068: ncbiprotein

S000303810
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:628457-628693:-1:exon

YJR108W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ABM1
locus tag: YJR108W
so part of: sequence
location: <628712..>629083
location: region:628712-629083:1
so has part: feature:628712-629083:1:exon
subclass of: SO_0000010

853572
type: Gene
SIO_000068: ncbigene

position:628712:1
position: 628712
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:629083:1
position: 629083
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:628712-629083:1:exon

YJR108W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ABM1
locus tag: YJR108W
product: Abm1p
transcript id: NM_001181766.1
SIO_010081: YJR108W
subclass of: SO_0000673
so part of: YJR108W
location: <628712..>629083
location: region:628712-629083:1
so has part: feature:628712-629083:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:628712-629083:1:exon

YJR108W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ABM1
locus tag: YJR108W
experiment: EXISTENCE:mutant phenotype:GO:0000226 microtubule cytoskeleton organization [PMID:10628851]
note: hypothetical protein; required for normal microtubule organization
codon start: 1
product: Abm1p
translation: MSWRYSILTVDGSFKIFIPWEIFLTWNFLSAAWLNSTESNTYIHYSTCWGTSDYTLNISVIEATTEKLVDTRLLTTLENATAWINSNSIDEDEDDMPHATNVADRLDGLSLSKRVYSICHYEF
SIO_010081: YJR108W
subclass of: SO_0000673
so part of: YJR108W
location: 628712..629083
location: region:628712-629083:1
so has part: feature:628712-629083:1:exon

NP_012642.1
type: Protein
SIO_000068: ncbiprotein

S000003869
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:628712-629083:1:exon

YJR109C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CPA2
locus tag: YJR109C
so part of: sequence
location: complement(<629585..>632941)
location: region:629585-632941:-1
so has part: feature:629585-632941:-1:exon
subclass of: SO_0000010

853573
type: Gene
SIO_000068: ncbigene

position:629585:-1
position: 629585
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:632941:-1
position: 632941
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:629585-632941:-1:exon

YJR109C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CPA2
locus tag: YJR109C
product: carbamoyl-phosphate synthase (glutamine-hydrolyzing) CPA2
transcript id: NM_001181767.3
SIO_010081: YJR109C
subclass of: SO_0000673
so part of: YJR109C
location: complement(<629585..>632941)
location: region:629585-632941:-1
so has part: feature:629585-632941:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:629585-632941:-1:exon

YJR109C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CPA2
locus tag: YJR109C
EC number: 6.3.5.5
experiment: EXISTENCE:direct assay:GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [PMID:8626695]
experiment: EXISTENCE:direct assay:GO:0005951 carbamoyl-phosphate synthase complex [PMID:206535]
experiment: EXISTENCE:mutant phenotype:GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [PMID:6358221]
experiment: EXISTENCE:mutant phenotype:GO:0006526 arginine biosynthetic process [PMID:8626695]
note: Large subunit of carbamoyl phosphate synthetase; carbamoyl phosphate synthetase catalyzes a step in the synthesis of citrulline, an arginine precursor
codon start: 1
product: carbamoyl-phosphate synthase (glutamine-hydrolyzing) CPA2
translation: MTSIYTSTEPTNSAFTTEDYKPQLVEGVNSVLVIGSGGLSIGQAGEFDYSGSQAIKALKEDNKFTILVNPNIATNQTSHSLADKIYYLPVTPEYITYIIELERPDAILLTFGGQTGLNCGVALDESGVLAKYNVKVLGTPIKTLITSEDRDLFASALKDINIPIAESFACETVDEALEAAERVKYPVIVRSAYALGGLGSGFANNASEMKELAAQSLSLAPQILVEKSLKGWKEVEYEVVRDRVGNCITVCNMENFDPLGVHTGDSMVFAPSQTLSDEEFHMLRSAAIKIIRHLGVIGECNVQYALQPDGLDYRVIEVNARLSRSSALASKATGYPLAYTAAKIGLGYTLPELPNPITKTTVANFEPSLDYIVAKIPKWDLSKFQYVDRSIGSSMKSVGEVMAIGRNYEEAFQKALRQVDPSLLGFQGSTEFGDQLDEALRTPTDRRVLAIGQALIHENYTVERVNELSKIDKWFLYKCMNIVNIYKELESVKSLSDLSKDLLQRAKKLGFSDKQIAVTINKHASTNINELEIRSLRKTLGIIPFVKRIDTLAAEFPAQTNYLYTTYNATKNDVEFNENGMLVLGSGVYRIGSSVEFDWCAVNTAKTLRDQGKKTIMINYNPETVSTDFDEVDRLYFEELSYERVMDIYELEQSEGCIISVGGQLPQNIALKLYDNGCNIMGTNPNDIDRAENRHKFSSILDSIDVDQPEWSELTSVEEAKLFASKVNYPVLIRPSYVLSGAAMSVVNNEEELKAKLTLASDVSPDHPVVMSKFIEGAQEIDVDAVAYNGNVLVHAISEHVENAGVHSGDASLVLPPQHLSDDVKIALKDIADKVAKAWKITGPFNMQIIKDGEHTLKVIECNIRASRSFPFVSKVLGVNFIEIAVKAFLGGDIVPKPVDLMLNKKYDYVATKVPQFSFTRLAGADPFLGVEMASTGEVASFGRDLIESYWTAIQSTMNFHVPLPPSGILFGGDTSREYLGQVASIVATIGYRIYTTNETTKTYLQEHIKEKNAKVSLIKFPKNDKRKLRELFQEYDIKAVFNLASKRAESTDDVDYIMRRNAIDFAIPLFNEPQTALLFAKCLKAKIAEKIKILESHDVIVPPEVRSWDEFIGFKAY
SIO_010081: YJR109C
subclass of: SO_0000673
so part of: YJR109C
location: complement(629585..632941)
location: region:629585-632941:-1
so has part: feature:629585-632941:-1:exon

NP_012643.3
type: Protein
SIO_000068: ncbiprotein

S000003870
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:629585-632941:-1:exon

YJR110W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: YMR1
locus tag: YJR110W
so part of: sequence
location: <633615..>635681
location: region:633615-635681:1
so has part: feature:633615-635681:1:exon
subclass of: SO_0000010

853574
type: Gene
SIO_000068: ncbigene

position:633615:1
position: 633615
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:635681:1
position: 635681
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:633615-635681:1:exon

YJR110W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: YMR1
locus tag: YJR110W
product: phosphatidylinositol-3-phosphatase YMR1
transcript id: NM_001181768.1
SIO_010081: YJR110W
subclass of: SO_0000673
so part of: YJR110W
location: <633615..>635681
location: region:633615-635681:1
so has part: feature:633615-635681:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:633615-635681:1:exon

YJR110W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: YMR1
locus tag: YJR110W
EC number: 3.1.3.64
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:21124907]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:genetic interaction:GO:0046856 phosphatidylinositol dephosphorylation [PMID:15169871]
experiment: EXISTENCE:mutant phenotype:GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity [PMID:15169871]
experiment: EXISTENCE:mutant phenotype:GO:0046856 phosphatidylinositol dephosphorylation [PMID:15169871]
note: Phosphatidylinositol 3-phosphate (PI3P) phosphatase; involved in various protein sorting pathways, including CVT targeting and endosome to vacuole transport; has similarity to the conserved myotubularin dual specificity phosphatase family
codon start: 1
product: phosphatidylinositol-3-phosphatase YMR1
translation: MEYIKIAKVSNVVLHRRGTATQGTLHLTTHHLIFESPQLSTEFWFPYPLIYGVHKNPGSTLLSKLTSTNQIQLEGTDSQNYKLYQGKDLWSFVNIKVIGKDYAVFSLDFGGDLHLQARKVYDSILNLTVLSNITQLYAFIYISNNLERKLPSPDSWDIYDPIKEFRRQGLDSKDETCPWRLSTVNEHYEFCPTYPSKLFVPRSTSDILLKHASKFRSQKRIPVLTYHHKATDCNILRSSQPLPGLINQRSIQDEKLVWESFNSFCNKDIRRTKHVIVDARPRTNALAQMALGGGTENMDNYNFFLADNNMGVDKSLKLPTVTRLFLGIDNIHIVSNTAAYMTEVICQGGDLNLPLEQNLIRSQKFSNWLKLNTLILKSVDMLLKSIIFNHSNVLVHCSDGWDRTSQVVSLLEICLDPFYRTFEGFMILVEKDWCSFGHRFLERSGHLNSDIRFHDNTMHSNFNDVDTNGDDLDIGVNTQDDYAEDDEGGEDETNLINLSRISKKFNENFKLNKKSLKFVSPVFQQFLDCVYQLLTQNPDLFEFNERFLRRLVYHLYSCQYGTFLSNSEKEKFQQNLPNKTKSVWDYFRSRRKQFINPNFIQRKRSGMNEHDQNLEEEEKVEWISPDLKKVQWWWQLYGRKDSEMNDELRHKRDSVPISVDKKSKEHSNSDGGKGLNLSIFGFDMFNRK
SIO_010081: YJR110W
subclass of: SO_0000673
so part of: YJR110W
location: 633615..635681
location: region:633615-635681:1
so has part: feature:633615-635681:1:exon

NP_012644.1
type: Protein
SIO_000068: ncbiprotein

S000003871
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:633615-635681:1:exon

YJR111C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PXP2
locus tag: YJR111C
so part of: sequence
location: complement(<635855..>636706)
location: region:635855-636706:-1
so has part: feature:635855-636706:-1:exon
subclass of: SO_0000010

853575
type: Gene
SIO_000068: ncbigene

position:635855:-1
position: 635855
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:636706:-1
position: 636706
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:635855-636706:-1:exon

YJR111C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PXP2
locus tag: YJR111C
product: Pxp2p
transcript id: NM_001181769.1
SIO_010081: YJR111C
subclass of: SO_0000673
so part of: YJR111C
location: complement(<635855..>636706)
location: region:635855-636706:-1
so has part: feature:635855-636706:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:635855-636706:-1:exon

YJR111C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PXP2
locus tag: YJR111C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005777 peroxisome [PMID:27392156]
note: Peroxisomal matrix protein with naturally active promoter; well-conserved in fungi; localized to peroxisomes under physiological growth conditions; levels of some amino acids are altered upon both knockout and overexpression, suggesting potential involvement of Pxp2p in amino acid metabolism or related cellular metabolic processes (needs further study); GFP-fusion protein displays inherent dual localization with large proportion localizing to cytosol
codon start: 1
product: Pxp2p
translation: MNQILNAQRLIQLSQFHPKLKNIWYLVAAATFSVCNEPQEIPKLYHYAMLLSNDNAHMYRFTLASQTIDLLRSELPMRKTLINENYQQPTFFQKQLTAKFREVILKTGPLAGLPRAINGLTMLKETTPDILVPHLDPIDPWEAAMGNSSPLSETSMRRKHDKTIQERDHTIQNGLRHWNSIYNKVSTRVVNNLNSSYPDLWYYTLVHVYGPLFAFDEILSAQETSLVIIASLVPQDVNPQLRGHLKGALNIGCDKETVEAVRGLAILISQWCGVSWKSGVVKL
SIO_010081: YJR111C
subclass of: SO_0000673
so part of: YJR111C
location: complement(635855..636706)
location: region:635855-636706:-1
so has part: feature:635855-636706:-1:exon

NP_012645.1
type: Protein
SIO_000068: ncbiprotein

S000003872
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:635855-636706:-1:exon

YJR112W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: NNF1
locus tag: YJR112W
so part of: sequence
location: <637030..>637635
location: region:637030-637635:1
so has part: feature:637030-637635:1:exon
subclass of: SO_0000010

853576
type: Gene
SIO_000068: ncbigene

position:637030:1
position: 637030
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:637635:1
position: 637635
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:637030-637635:1:exon

YJR112W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: NNF1
locus tag: YJR112W
product: MIND complex subunit NNF1
transcript id: NM_001181770.3
SIO_010081: YJR112W
subclass of: SO_0000673
so part of: YJR112W
location: <637030..>637635
location: region:637030-637635:1
so has part: feature:637030-637635:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:637030-637635:1:exon

YJR112W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: NNF1
locus tag: YJR112W
experiment: EXISTENCE:direct assay:GO:0000444 MIS12/MIND type complex [PMID:14633972]
experiment: EXISTENCE:direct assay:GO:0000776 kinetochore [PMID:14657030]
experiment: EXISTENCE:direct assay:GO:0007059 chromosome segregation [PMID:12455957]
note: Essential component of the outer kinetochore MIND complex; joins kinetochore subunits contacting DNA to those contacting microtubules; required for kinetochore bi-orientation and accurate chromosome segregation; complex consists of Mtw1p, Nnf1p, Nsl1p and Dsn1p; homologous to metazoan CENP-H proteins
codon start: 1
product: MIND complex subunit NNF1
translation: MVNSHGIRYIRLKQVFNRALDQSISKLQSWDKVSSCFPQYVNSKQGAINVANCQRQLTEFWTELCQREFKEIMEERNVEQKLNELDELILEAKERYTDRDQDEVNKGPAIDELSSKELVECHLYSQRMHAIHEIDERLAKVNEMNDQLAQELKDLETQVEVEKNEIGKMYDEYLGSHTDQPANVLLVQSLNDMVLELKENY
SIO_010081: YJR112W
subclass of: SO_0000673
so part of: YJR112W
location: 637030..637635
location: region:637030-637635:1
so has part: feature:637030-637635:1:exon

NP_012646.3
type: Protein
SIO_000068: ncbiprotein

S000003873
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:637030-637635:1:exon

YJR112W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJR112W-A
so part of: sequence
location: <637790..>638168
location: region:637790-638168:1
so has part: feature:637790-638168:1:exon
subclass of: SO_0000010

1466470
type: Gene
SIO_000068: ncbigene

position:637790:1
position: 637790
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:638168:1
position: 638168
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:637790-638168:1:exon

YJR112W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJR112W-A
product: uncharacterized protein
transcript id: NM_001184523.1
SIO_010081: YJR112W-A
subclass of: SO_0000673
so part of: YJR112W-A
location: join(<637790..637809,637859..>638168)
location: region:637790-638168:1
so has part: feature:637790-637809:1:exon
so has part: feature:637859-638168:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:637790-637809:1:exon

position:637809:1
position: 637809
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:637859-638168:1:exon

position:637859:1
position: 637859
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YJR112W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJR112W-A
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
note: hypothetical protein; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum; identified based on homology to Ashbya gossypii
codon start: 1
product: uncharacterized protein
translation: MVQLRRTITTNKVFQAITSTNDKVAHFVVFMWESWLFVKMFAEDIVTFRKLQANKYVLGVLICSLCASVTSEFAQSVVSRGQRVFDVKDIICNFWGSLLGVGIAFYQDR
SIO_010081: YJR112W-A
subclass of: SO_0000673
so part of: YJR112W-A
location: join(637790..637809,637859..638168)
location: region:637790-638168:1
so has part: feature:637790-637809:1:exon
so has part: feature:637859-638168:1:exon

NP_878107.1
type: Protein
SIO_000068: ncbiprotein

S000028513
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:637790-637809:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:637859-638168:1:exon

YJR113C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: uS7m
gene: RSM7
locus tag: YJR113C
gene synonym: uS7m
so part of: sequence
location: complement(<638232..>638975)
location: region:638232-638975:-1
so has part: feature:638232-638975:-1:exon
subclass of: SO_0000010

853578
type: Gene
SIO_000068: ncbigene

position:638232:-1
position: 638232
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:638975:-1
position: 638975
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:638232-638975:-1:exon

YJR113C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: uS7m
gene: RSM7
locus tag: YJR113C
gene synonym: uS7m
product: mitochondrial 37S ribosomal protein RSM7
transcript id: NM_001181771.1
SIO_010081: YJR113C
subclass of: SO_0000673
so part of: YJR113C
location: complement(<638232..>638975)
location: region:638232-638975:-1
so has part: feature:638232-638975:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:638232-638975:-1:exon

YJR113C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: uS7m
gene: RSM7
locus tag: YJR113C
gene synonym: uS7m
experiment: EXISTENCE:curator inference:GO:0032543 mitochondrial translation [PMID:11278769]
experiment: EXISTENCE:direct assay:GO:0003735 structural constituent of ribosome [PMID:11278769]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005763 mitochondrial small ribosomal subunit [PMID:11278769]
note: Mitochondrial ribosomal protein of the small subunit; has similarity to E. coli S7 ribosomal protein
codon start: 1
product: mitochondrial 37S ribosomal protein RSM7
translation: MLHCARRYMLVRPRLLWQSGTCVARFQSSVRTPASEPSAEKGVDEWLEAINELREEFSAKEYLPETSLAPPGQSKVDLLQGSQAGSKIKPTAEQLAQWEALKSVPIPPRKNATLDHITNMIMRHGKKEKAQTILSRALYLVYCQTRQDPIQALEKSLDELAPLMMTKTFNTGVAKASVIPVPLNKRQRNRIAWNWIVQSANQRVSSDFAVRLGEELTAIAKGTSSAFEKRDQIHKTAIAHRAYIQLK
SIO_010081: YJR113C
subclass of: SO_0000673
so part of: YJR113C
location: complement(638232..638975)
location: region:638232-638975:-1
so has part: feature:638232-638975:-1:exon

NP_012647.1
type: Protein
SIO_000068: ncbiprotein

S000003874
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:638232-638975:-1:exon

YJR115W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YJR115W
so part of: sequence
location: <639942..>640451
location: region:639942-640451:1
so has part: feature:639942-640451:1:exon
subclass of: SO_0000010

853579
type: Gene
SIO_000068: ncbigene

position:639942:1
position: 639942
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:640451:1
position: 640451
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:639942-640451:1:exon

YJR115W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YJR115W
product: uncharacterized protein
transcript id: NM_001181773.3
SIO_010081: YJR115W
subclass of: SO_0000673
so part of: YJR115W
location: <639942..>640451
location: region:639942-640451:1
so has part: feature:639942-640451:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:639942-640451:1:exon

YJR115W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YJR115W
note: hypothetical protein; YJR115W has a paralog, ECM13, that arose from the whole genome duplication
codon start: 1
product: uncharacterized protein
translation: MFTNTRTILIYNSKVMNTHTHTHTHTHTHIYIYTGDQVSVRGRLLSLKFFKVLKLFFPSPTSLATSHPPLSSMSPYMTIPQQYLYISKIRSKLSQCALTRHHHRELDLRKMVGHANMLDRILDEIDEIDSEVVLCDAADGSSTAEAHSASPASSDSSPLTNNIRPISIM
SIO_010081: YJR115W
subclass of: SO_0000673
so part of: YJR115W
location: 639942..640451
location: region:639942-640451:1
so has part: feature:639942-640451:1:exon

NP_012649.3
type: Protein
SIO_000068: ncbiprotein

S000003876
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:639942-640451:1:exon

YJR116W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TDA4
locus tag: YJR116W
so part of: sequence
location: <640825..>641664
location: region:640825-641664:1
so has part: feature:640825-641664:1:exon
subclass of: SO_0000010

853580
type: Gene
SIO_000068: ncbigene

position:640825:1
position: 640825
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:641664:1
position: 641664
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:640825-641664:1:exon

YJR116W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TDA4
locus tag: YJR116W
product: Tda4p
transcript id: NM_001181774.1
SIO_010081: YJR116W
subclass of: SO_0000673
so part of: YJR116W
location: <640825..>641664
location: region:640825-641664:1
so has part: feature:640825-641664:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:640825-641664:1:exon

YJR116W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TDA4
locus tag: YJR116W
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
note: Protein distantly similar to ceramide synthases, Lag1p and Lac1p; null mutant is sensitive to expression of the top1-T722A allele; mutation confers sensitivity to copper
codon start: 1
product: Tda4p
translation: MNANSTTTAIGLTSPFEKLSFFPHSSNLILAHLHEIIFSFVFYQLAFSVVAPFLNKVVFRKHYTTIRDPLLKIDFNVHTVSMIQAVVSNTVLLPTLTTPMHYNVVTYTDSYSSMVSSLSAGYFIWDLTMCVRYFKLYGLEFTGHAIGSVYVMLLSLRPFCQPWIGRFLIYEASTPFVNINWFIMQCNAKSKNSIPLWFNVVNGLLLMTVFFVVRICWGSIASALLFRQMWKVRDELPKFSAVTMMSLNIFMNLLNVLWFKKMIRIAKKLAKPAPTSKLD
SIO_010081: YJR116W
subclass of: SO_0000673
so part of: YJR116W
location: 640825..641664
location: region:640825-641664:1
so has part: feature:640825-641664:1:exon

NP_012650.1
type: Protein
SIO_000068: ncbiprotein

S000003877
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:640825-641664:1:exon

YJR117W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: AFC1
alternative label: PIO2
gene: STE24
locus tag: YJR117W
gene synonym: AFC1; PIO2
so part of: sequence
location: <642007..>643368
location: region:642007-643368:1
so has part: feature:642007-643368:1:exon
subclass of: SO_0000010

853581
type: Gene
SIO_000068: ncbigene

position:642007:1
position: 642007
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:643368:1
position: 643368
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:642007-643368:1:exon

YJR117W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: AFC1
alternative label: PIO2
gene: STE24
locus tag: YJR117W
gene synonym: AFC1; PIO2
product: zinc metalloprotease
transcript id: NM_001181775.1
SIO_010081: YJR117W
subclass of: SO_0000673
so part of: YJR117W
location: <642007..>643368
location: region:642007-643368:1
so has part: feature:642007-643368:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:642007-643368:1:exon

YJR117W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: AFC1
alternative label: PIO2
gene: STE24
locus tag: YJR117W
gene synonym: AFC1; PIO2
EC number: 3.4.24.84
experiment: EXISTENCE:direct assay:GO:0004222 metalloendopeptidase activity [PMID:11581258|PMID:27129777]
experiment: EXISTENCE:direct assay:GO:0005741 mitochondrial outer membrane [PMID:16407407]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:11581258]
experiment: EXISTENCE:direct assay:GO:0016485 protein processing [PMID:27129777]
experiment: EXISTENCE:direct assay:GO:0071432 peptide mating pheromone maturation involved in positive regulation of conjugation with cellular fusion [PMID:11581258]
experiment: EXISTENCE:genetic interaction:GO:0071432 peptide mating pheromone maturation involved in positive regulation of conjugation with cellular fusion [PMID:10825201|PMID:11581258|PMID:9065405]
experiment: EXISTENCE:genetic interaction:GO:0071586 CAAX-box protein processing [PMID:9065405]
experiment: EXISTENCE:genetic interaction:GO:0071712 ER-associated misfolded protein catabolic process [PMID:26771486]
experiment: EXISTENCE:mutant phenotype:GO:0005637 nuclear inner membrane [PMID:18923140]
experiment: EXISTENCE:mutant phenotype:GO:0071432 peptide mating pheromone maturation involved in positive regulation of conjugation with cellular fusion [PMID:10825201|PMID:9065405]
experiment: EXISTENCE:mutant phenotype:GO:0071586 CAAX-box protein processing [PMID:9065405]
experiment: EXISTENCE:mutant phenotype:GO:0071712 ER-associated misfolded protein catabolic process [PMID:26771486]
experiment: EXISTENCE:mutant phenotype:GO:0120236 negative regulation of post-translational protein targeting to membrane, translocation [PMID:32513868]
note: Highly conserved zinc metalloprotease; component of the ER quality control mechanism that removes faulty proteins clogging translocation channels; inhibits SRP-independent translocation into the ER; has two roles in a-factor maturation, C-terminal CAAX proteolysis and the first step of N-terminal proteolytic processing; cleaves isoprenylated and non-prenylated oligopeptides; human homolog ZMPSTE24 implicated in mandibuloacral dysplasia (MAD), and complements the null mutant
codon start: 1
product: zinc metalloprotease
translation: MFDLKTILDHPNIPWKLIISGFSIAQFSFESYLTYRQYQKLSETKLPPVLEDEIDDETFHKSRNYSRAKAKFSIFGDVYNLAQKLVFIKYDLFPKIWHMAVSLLNAVLPVRFHMVSTVAQSLCFLGLLSSLSTLVDLPLSYYSHFVLEEKFGFNKLTVQLWITDMIKSLTLAYAIGGPILYLFLKIFDKFPTDFLWYIMVFLFVVQILAMTIIPVFIMPMFNKFTPLEDGELKKSIESLADRVGFPLDKIFVIDGSKRSSHSNAYFTGLPFTSKRIVLFDTLVNSNSTDEITAVLAHEIGHWQKNHIVNMVIFSQLHTFLIFSLFTSIYRNTSFYNTFGFFLEKSTGSFVDPVITKEFPIIIGFMLFNDLLTPLECAMQFVMSLISRTHEYQADAYAKKLGYKQNLCRALIDLQIKNLSTMNVDPLYSSYHYSHPTLAERLTALDYVSEKKKN
SIO_010081: YJR117W
subclass of: SO_0000673
so part of: YJR117W
location: 642007..643368
location: region:642007-643368:1
so has part: feature:642007-643368:1:exon

NP_012651.1
type: Protein
SIO_000068: ncbiprotein

S000003878
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:642007-643368:1:exon

YJR118C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ILM1
locus tag: YJR118C
so part of: sequence
location: complement(<643490..>644101)
location: region:643490-644101:-1
so has part: feature:643490-644101:-1:exon
subclass of: SO_0000010

853582
type: Gene
SIO_000068: ncbigene

position:643490:-1
position: 643490
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:644101:-1
position: 644101
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:643490-644101:-1:exon

YJR118C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ILM1
locus tag: YJR118C
product: Ilm1p
transcript id: NM_001181776.3
SIO_010081: YJR118C
subclass of: SO_0000673
so part of: YJR118C
location: complement(<643490..>644101)
location: region:643490-644101:-1
so has part: feature:643490-644101:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:643490-644101:-1:exon

YJR118C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ILM1
locus tag: YJR118C
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0000002 mitochondrial genome maintenance [PMID:10628851]
note: hypothetical protein; may be involved in mitochondrial DNA maintenance; required for slowed DNA synthesis-induced filamentous growth
codon start: 1
product: Ilm1p
translation: MAQALNSTNIAFFRVAFLFTIAFFCLKNVNSILQNTYFIVLTQAMNLPQLTLSRYSGQLGLFALLFTLNGVHDLIPLLENNVKYFQSVVPVRLLIFFILTSISYLWESNFYVHNNSVFIYCFAEVWINFLLYNAIREEKNEEFKRLNQFMVNDEDIEEPQPFTVKTETTEIIEIINDEENDDEDGKDNDDNNEKGNDDSDAKK
SIO_010081: YJR118C
subclass of: SO_0000673
so part of: YJR118C
location: complement(643490..644101)
location: region:643490-644101:-1
so has part: feature:643490-644101:-1:exon

NP_012652.3
type: Protein
SIO_000068: ncbiprotein

S000003879
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:643490-644101:-1:exon

YJR119C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: KDM5
gene: JHD2
locus tag: YJR119C
gene synonym: KDM5
so part of: sequence
location: complement(<644304..>646490)
location: region:644304-646490:-1
so has part: feature:644304-646490:-1:exon
subclass of: SO_0000010

853583
type: Gene
SIO_000068: ncbigene

position:644304:-1
position: 644304
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:646490:-1
position: 646490
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:644304-646490:-1:exon

YJR119C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: KDM5
gene: JHD2
locus tag: YJR119C
gene synonym: KDM5
product: histone demethylase
transcript id: NM_001181777.1
SIO_010081: YJR119C
subclass of: SO_0000673
so part of: YJR119C
location: complement(<644304..>646490)
location: region:644304-646490:-1
so has part: feature:644304-646490:-1:exon