Saccharomyces cerevisiae S288C chromosome IX, complete sequence.
type: Entry
definition: Saccharomyces cerevisiae S288C chromosome IX, complete sequence.
sequence version: NC_001141.2
sequence date: 2023-01-18
sequence: sequence
division: CON
label: NC_001141.2
type: RefSeq
SIO_000068: refseq
dblink: PRJNA128
keyword: RefSeq
source: Saccharomyces cerevisiae S288C
organism: Saccharomyces cerevisiae S288C
taxonomy: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
reference: 1
references: 34897464
reference: 2
references: 9169870
reference: 3
references: 8849441
reference: 4
reference: 5
reference: 6
reference: 7
comment: REVIEWED REFSEQ: This record has been curated by SGD. The reference\nsequence is identical to BK006942.\n\nOn Apr 26, 2011 this sequence version replaced NC_001141.1.\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: SGD\nAnnotation Status :: Full Annotation\nAnnotation Version :: R64-3-1\nURL :: http://www.yeastgenome.org/\n##Genome-Annotation-Data-END##\nCOMPLETENESS: full length.

sequence
subclass of: SO_0000340
sequence length: 439888
topology: linear
so has quality: SO_0000987
location: 1..439888
location: region:1-439888:1
RO_0002162: 559292

NC_001141
type: RefSeq
SIO_000068: refseq

PRJNA128
type: BioProject
SIO_000068: bioproject

1
title: New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources
author: Engel, S.R.
author: Wong, E.D.
author: Nash, R.S.
author: Aleksander, S.
author: Alexander, M.
author: Douglass, E.
author: Karra, K.
author: Miyasato, S.R.
author: Simison, M.
author: Skrzypek, M.S.
author: Weng, S.
author: Cherry, J.M.
journal: Genetics 220 (4) (2022)
pubmed: 34897464

34897464
type: PubMed
SIO_000068: pubmed

2
title: The nucleotide sequence of Saccharomyces cerevisiae chromosome IX
author: Churcher, C.
author: Bowman, S.
author: Badcock, K.
author: Bankier, A.
author: Brown, D.
author: Chillingworth, T.
author: Connor, R.
author: Devlin, K.
author: Gentles, S.
author: Hamlin, N.
author: Harris, D.
author: Horsnell, T.
author: Hunt, S.
author: Jagels, K.
author: Jones, M.
author: Lye, G.
author: Moule, S.
author: Odell, C.
author: Pearson, D.
author: Rajandream, M.
author: Rice, P.
author: Rowley, N.
author: Skelton, J.
author: Smith, V.
author: Barrell, B. et al.
journal: Nature 387 (6632 SUPPL), 84-87 (1997)
pubmed: 9169870

9169870
type: PubMed
SIO_000068: pubmed

3
title: Life with 6000 genes
author: Goffeau, A.
author: Barrell, B.G.
author: Bussey, H.
author: Davis, R.W.
author: Dujon, B.
author: Feldmann, H.
author: Galibert, F.
author: Hoheisel, J.D.
author: Jacq, C.
author: Johnston, M.
author: Louis, E.J.
author: Mewes, H.W.
author: Murakami, Y.
author: Philippsen, P.
author: Tettelin, H.
author: Oliver, S.G.
journal: Science 274 (5287), 546 (1996)
pubmed: 8849441

8849441
type: PubMed
SIO_000068: pubmed

4
title: Direct Submission
journal: Submitted (13-JAN-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA

5
title: Direct Submission
journal: Submitted (04-MAY-2012) Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA
comments: Protein update by submitter

6
title: Direct Submission
journal: Submitted (31-MAR-2011) Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA
comments: Sequence update by submitter

7
title: Direct Submission
journal: Submitted (14-DEC-2009) Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA

position:1:1
position: 1
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:439888:1
position: 439888
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

feature:1-439888:1:source
so part of: sequence
organism: Saccharomyces cerevisiae S288C
mol type: genomic DNA
strain: S288C
chromosome: IX

559292
type: Taxonomy
SIO_000068: taxonomy

telomere
type: Telomere
subclass of: SO_0000624
RO_0002162: 559292
note: TEL09L; Telomeric region on the left arm of Chromosome IX; composed of an X element core sequence, X element combinatorial repeats, a long Y' element, and a short terminal stretch of telomeric repeats
so part of: sequence
location: complement(1..7784)
location: region:1-7784:-1
so has part: feature:1-7784:-1:region

S000028896
type: SGD
SIO_000068: sgd

position:1:-1
position: 1
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:7784:-1
position: 7784
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:1-7784:-1:region

YIL177C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YIL177C
so part of: sequence
location: complement(<483..>6147)
location: region:483-6147:-1
so has part: feature:483-6147:-1:exon
subclass of: SO_0000010

854630
type: Gene
SIO_000068: ncbigene

position:483:-1
position: 483
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:6147:-1
position: 6147
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:483-6147:-1:exon

YIL177C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YIL177C
product: Y' element ATP-dependent helicase
transcript id: NM_001179522.1
SIO_010081: YIL177C
subclass of: SO_0000673
so part of: YIL177C
location: complement(join(<483..4598,4987..>6147))
location: region:483-6147:-1
so has part: feature:4987-6147:-1:exon
so has part: feature:483-4598:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:4987-6147:-1:exon

position:4987:-1
position: 4987
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:483-4598:-1:exon

position:4598:-1
position: 4598
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YIL177C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YIL177C
EC number: 3.6.4.12
note: Putative Y' element ATP-dependent helicase
codon start: 1
product: Y' element ATP-dependent helicase
translation: MKVSDRRKFEKANFDEFESALNNKNDLVHCPSITLFESIPTEVRSFYEDEKSGLIKVVKFRTGAMDRKRSFEKVVISVMVGKNVKKFLTFVEDEPDFQGGPIPSKYLIPKKINLMVYTLFQVHTLKFNRKDYDTLSLFYLNRGYYNELSFRVLERCHEIASARPNDSSTMRTFTDFVSGAPIVRSLQKSTIRKYGYNLAPYMFLLLHVDELSIFSAYQASLPGEKKVDTERLKRDLCPRKPIEIKYFSQICNDMMNKKDRLGDILHIILRACALNFGAGPRGGAGDEEDRSITNEEPIIPSVDEHGLKVCKLRSPNTPRRLRKTLDAVKALLVSSCACTARDLDIFDDNNGVAMWKWIKILYHEVAQETTLKDSYRITLVPSSDGISLLAFAGPQRNVYVDDTTRRIQLYTDYNKNGSSEPRLKTLDGLTSDYVFYFVTVLRQMQICALGNSYDAFNHDPWMDVVGFEDPNQVTNRDISRIVLYSYMFLNTAKGCLVEYATFRQYMRELPKNAPQKLNFREMRQGLIALGRHCVGSRFETDLYESATSELMANHSVQTGRNIYGVDSFSLTSVSGTTATLLQERASERWIQWLGLESDYHCSFSSTRNAEDVVAGEAASSNHHQKISRVTRKRPREPKSTNDILVAGQKLFGSSFEFRDLHQLRLCYEIYMADTPSVAVQAPPGYGKTELFHLPLIALASKGDVEYVSFLFVPYTVLLANCMIRLGRCGCLNVAPVRNFIEEGYDGVTDLYVGIYDDLASTNFTDRIAAWENIVECTFRTNNVKLGYLIVDEFHNFETEVYRQSQFGGITNLDFDAFEKAIFLSGTAPEAVADAALQRIGLTGLAKKSMDINELKRSEDLSRGLSSYPTRMFNLIKEKSEVPLGHVHKIRKKVESQPEEALKLLLALFESEPESKAIVVASTTNEVEELACSWRKYFRVVWIHGKLGAAEKVSRTKEFVTDGSMQVLIGTKLVTEGIDIKQLMMVIMLDNRLNIIELIQGVGRLRDGGLCYLLSRKNSWAARNRKGELPPIKEGCITEQVREFYGLESKKGKKGQHVGCCGSRTDLSADTVELIERMDRLAEKQATASMSIVALPSSFQESNSSDRYRKYCSSDEDSNTCIHGSANASTNASTNAITTASTNVRTNATTNASTNATTNASTNASTNATTNASTNATTNSSTNATTTASTNVRTSATTTASINVRTSATTTESTNSSTNATTTESTNSSTNATTTESTNSNTSATTTASINVRTSATTTESTNSSTSATTTASINVRTSATTTKSINSSTNATTTESTNSNTNATTTESTNSSTNATTTESTNSSTNATTTESTNSNTSAATTESTNSNTSATTTESTNASAKEDANKDGNAEDNRFHPVTDINKESYKRKGSQMVLLERKKLKAQFPNTSENMNVLQFLGFRSDEIKHLFLYGIDIYFCPEGVFTQYGLCKGCQKMFELCVCWAGQKVSYRRIAWEALAVERMLRNDEEYKEYLEDIEPYHGDPVGYLKYFSVKRREIYSQIQRNYAWYLAITRRRETISVLDSTRGKQGSQVFRMSGRQIKELYFKVWSNLRESKTEVLQYFLNWDEKKCQEEWEAKDDTVVVEALEKGGVFQRLRSMTSAGLQGPQYVKLQFSRHHRQLRSRYELSLGMHLRDQIALGVTPSKVPHWTAFLSMLIGLFYNKTFRQKLEYLLEQISEVWLLPHWLDLANVEVLAADDTRVPLYMLMVAVHKELDSDDVPDGRFDILLCRDSSREVGE
SIO_010081: YIL177C
subclass of: SO_0000673
so part of: YIL177C
location: complement(join(483..4598,4987..6147))
location: region:483-6147:-1
so has part: feature:4987-6147:-1:exon
so has part: feature:483-4598:-1:exon

NP_012092.1
type: Protein
SIO_000068: ncbiprotein

S000001439
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:4987-6147:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:483-4598:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS902; Putative replication origin; identified in multiple array studies, not yet confirmed by plasmid-based assay
so part of: sequence
location: 7470..8793
location: region:7470-8793:1
so has part: feature:7470-8793:1:region

S000130156
type: SGD
SIO_000068: sgd

position:7470:1
position: 7470
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:8793:1
position: 8793
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:7470-8793:1:region

YIL176C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PAU14
locus tag: YIL176C
so part of: sequence
location: complement(<8793..>9155)
location: region:8793-9155:-1
so has part: feature:8793-9155:-1:exon
subclass of: SO_0000010

854631
type: Gene
SIO_000068: ncbigene

position:8793:-1
position: 8793
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:9155:-1
position: 9155
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:8793-9155:-1:exon

YIL176C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PAU14
locus tag: YIL176C
product: seripauperin PAU14
transcript id: NM_001179521.1
SIO_010081: YIL176C
subclass of: SO_0000673
so part of: YIL176C
location: complement(<8793..>9155)
location: region:8793-9155:-1
so has part: feature:8793-9155:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:8793-9155:-1:exon

YIL176C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PAU14
locus tag: YIL176C
note: hypothetical protein; member of the seripauperin multigene family encoded mainly in subtelomeric regions; identical to Pau1p
codon start: 1
product: seripauperin PAU14
translation: MVKLTSIAAGVAAIAATASATTTLAQSDERVNLVELGVYVSDIRAHLAQYYMFQAAHPTETYPVEVAEAVFNYGDFTTMLTGISPDQVTRMITGVPWYSSRLKPAISSALSKDGIYTIAN
SIO_010081: YIL176C
subclass of: SO_0000673
so part of: YIL176C
location: complement(8793..9155)
location: region:8793-9155:-1
so has part: feature:8793-9155:-1:exon

NP_012093.1
type: Protein
SIO_000068: ncbiprotein

S000001438
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:8793-9155:-1:exon

YIL175W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YIL175W
note: hypothetical protein; classified as pseudogene because there is no ATG at the beginning of this ORF
pseudo: true
so part of: sequence
location: 9183..9500
location: region:9183-9500:1
so has part: feature:9183-9500:1:exon

854632
type: Gene
SIO_000068: ncbigene

S000001437
type: SGD
SIO_000068: sgd

position:9183:1
position: 9183
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:9500:1
position: 9500
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:9183-9500:1:exon

YIL175W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YIL175W
pseudo: true
SIO_010081: YIL175W
subclass of: SO_0000673
so part of: YIL175W
location: 9183..9500
location: region:9183-9500:1
so has part: feature:9183-9500:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:9183-9500:1:exon

YIL174W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YIL174W
note: hypothetical protein
pseudo: true
so part of: sequence
location: 9469..9696
location: region:9469-9696:1
so has part: feature:9469-9696:1:exon

854633
type: Gene
SIO_000068: ncbigene

S000001436
type: SGD
SIO_000068: sgd

position:9469:1
position: 9469
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:9696:1
position: 9696
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:9469-9696:1:exon

YIL174W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YIL174W
pseudo: true
SIO_010081: YIL174W
subclass of: SO_0000673
so part of: YIL174W
location: 9469..9696
location: region:9469-9696:1
so has part: feature:9469-9696:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:9469-9696:1:exon

YIL173W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: VTH1
locus tag: YIL173W
so part of: sequence
location: <11492..>16141
location: region:11492-16141:1
so has part: feature:11492-16141:1:exon
subclass of: SO_0000010

854634
type: Gene
SIO_000068: ncbigene

position:11492:1
position: 11492
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:16141:1
position: 16141
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:11492-16141:1:exon

YIL173W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: VTH1
locus tag: YIL173W
product: signal sequence-binding protein
transcript id: NM_001179519.1
SIO_010081: YIL173W
subclass of: SO_0000673
so part of: YIL173W
location: <11492..>16141
location: region:11492-16141:1
so has part: feature:11492-16141:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:11492-16141:1:exon

YIL173W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: VTH1
locus tag: YIL173W
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005768 endosome [PMID:14562095]
experiment: EXISTENCE:genetic interaction:GO:0005048 signal sequence binding [PMID:8662642]
experiment: EXISTENCE:genetic interaction:GO:0006896 Golgi to vacuole transport [PMID:8662642]
note: Putative membrane glycoprotein; has strong similarity to Vth2p and Pep1p/Vps10p; may be involved in vacuolar protein sorting
codon start: 1
product: signal sequence-binding protein
translation: MALFRALYIIWVFLLIPLSNAEEFTPKVTRTLSRYVFDIVNFDDSNTLIRAEEDSVEISFDAGENWKTIDEIEEPIESFVVDPFRGHDRAFAFVKTAPKFYVTDDQGKSWRPLTIPISEKASNYFCDVTTHPIKKKHLIIRCDLLTIKNSGLMYVGREIYTTNDGVSFSQVKPSFGKIDGHISTARCDFIKSSEDSDLGGNDASILCLFRNTEYIESTGSTIDKSELILSADGGETFKELVQFKDKVVSRYEILKHHVIVLTQDDMYNEMSSTNIWISNDVSTFQVARTPTKIRHVNMGQIHEDSIGRIVLPVSRERDDEDSNQPGAAEVLISDSEGLKFLPINWIPNNQFGYINVAYPGFLKGTFFGSFHPFIEYSDRKRKYSRQKVREETKVSVDNGLTWTNLKVVDRENVDLFGCDVTKPERCSLQTHFYDLRNLNPSAGIMMISGIVGDGSAYNWKEEKTFISRDSGLTWRLVHNSTGLYTTGDLGNIIMYIPYRSNENGDVPSKFYYSLDQGKTWGEYDLIMPIYPYRLVSTISDGSGSKFILTGTSITEDPIFITYSIDFSAVFDYKSCEEGDFEDWNLADGKCVNGAKYKYRRRKQDAQCLVKKAFKDLSLDETPCNSCTGSDYECSFEFVRDAKGDCIPDYNLIALSDICDKSKGKSVLVKPLQLIKGDKCKTPMKIESVDIPCDEIPKEGSSDKEIVTTENKFDFEIKFYQYFDTVADESLVMLNSIGDAYISHDGGQTIKRFDTDGEKIVEIVFNPYFNSSAYLFGSKGNIFLTHDRGYSFMIAKLPEARQLGMPLDFSAKAQDTFIYYGGKNCESILSPECHAVAYLTKDGGETFTEMLDNAIHCEFAGTLFKYPSNDDMVMCQVKEKFSQTRSLVSSTDFFQDDRKTVFENIIGYLSTGGYIIVAVPHEDNELRAYVTNDGAEFTEAKFPYDEDIGKQDAFTILGSEEGSIFLHLATNLESGHDFGNLLKSNSNGTSFVTLEHAVNRNTFGYVDFEKVQGLEGIIITNIVSNSEKVGENKEDEQLKTKITFNDGSDWNFLKPPKKDSEGKKFPCDSVSLDKCSLHLHGYTERKDIRDTYSSGSALGMMFGVGNVGDRLLPYEECSTFLTTDGGETWTEVKKGPHQWEYGDHGGVLVLVPENAETDSISYSTDFGKTWKDYKFCGDKVLVKDIITVPRDSALRFLLFGEAKNMGSGSFRTYTIDFRNIFERQCEFDITGRKRADFKYSPLGSRTGCLFGHKTEFLRKTDEKCFIGNIPLSEFSRNVKNCPCTRQDFECDYNFYKASDGTCKLVKGLSSANGADICKKEPDLIEYYDSSGYRKIPLSTCKGGLKLDAHLAPHPCPGKEKAFREKYSINTGAYALVFVTILLVIFFVAWFVYDRGIRRNGGFSRFEEIRLGDDGLIENNRTDRVVNIIVRLGLCISLITKSAFQRAKAGTAQLSSKFRARFGNKKGATYSSLLHDQLSDEPDGFHEDSNDLSSFRGQGSNSEIEQEDVDTSQQEHTLRTDLLGASNIPDALPARSASHESDLAAARSEDK
SIO_010081: YIL173W
subclass of: SO_0000673
so part of: YIL173W
location: 11492..16141
location: region:11492-16141:1
so has part: feature:11492-16141:1:exon

NP_012095.1
type: Protein
SIO_000068: ncbiprotein

S000001435
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:11492-16141:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS904; Putative replication origin; identified in multiple array studies, not yet confirmed by plasmid-based assay
so part of: sequence
location: 16141..16784
location: region:16141-16784:1
so has part: feature:16141-16784:1:region

S000130157
type: SGD
SIO_000068: sgd

position:16784:1
position: 16784
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:16141-16784:1:region

YIL172C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: IMA3
locus tag: YIL172C
so part of: sequence
location: complement(<16784..>18553)
location: region:16784-18553:-1
so has part: feature:16784-18553:-1:exon
subclass of: SO_0000010

854635
type: Gene
SIO_000068: ncbigene

position:16784:-1
position: 16784
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:18553:-1
position: 18553
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:16784-18553:-1:exon

YIL172C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: IMA3
locus tag: YIL172C
product: oligo-1,6-glucosidase IMA3
transcript id: NM_001179518.1
SIO_010081: YIL172C
subclass of: SO_0000673
so part of: YIL172C
location: complement(<16784..>18553)
location: region:16784-18553:-1
so has part: feature:16784-18553:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:16784-18553:-1:exon

YIL172C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: IMA3
locus tag: YIL172C
EC number: 3.2.1.10
experiment: EXISTENCE:direct assay:GO:0004574 oligo-1,6-glucosidase activity [PMID:20471265]
experiment: EXISTENCE:direct assay:GO:0004575 sucrose alpha-glucosidase activity [PMID:24649402]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:genetic interaction:GO:0046352 disaccharide catabolic process [PMID:20562106|PMID:20471265]
experiment: EXISTENCE:mutant phenotype:GO:0004574 oligo-1,6-glucosidase activity [PMID:20562106]
note: Alpha-glucosidase; weak, but broad substrate specificity for alpha-1,4- and alpha-1,6-glucosides; member of IMA isomaltase family; not required for isomaltose utilization, but Ima3p overexpression allows the ima1 null mutant to grow on isomaltose; lower activitiy and thermostability in vitro than Ima2p despite sequence difference of only 3 amino acids; cleaves alpha-1,3 linkage of nigerose and turanose, but not alpha-1,5 of leucrose; identical to IMA4
codon start: 1
product: oligo-1,6-glucosidase IMA3
translation: MTISSAHPETEPKWWKEATIYQIYPASFKDSNNDGWGDMKGIASKLEYIKELGTDAIWISPFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWRSYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVAGLPDAPVIDENSKWQLSDPFTMNGPRIHEFHQEMNKFIRNRVKDGREIMTVGEMRHATDETKRLYTSASRHELSELFNFSHTDVGTSPKFRQNLIPYELKDWKVALAELFRYVNGTDCWSTIYLENHDQPRSITRFGDDSPKNRVISGKLLSVLLVSLSGTLYVYQGQELGEINFKNWPIEKYEDVEVRNNYDAIKEEHGENSKEMKRFLEAIALISRDHARTPMQWSREEPNAGFSGPNAKPWFYLNESFREGINAEDESKDPNSVLNFWKEALRFRKAHKDITVYGYDFEFIDLDNKKLFSFTKKYDNKTLFAALNFSSDSIDFTIPNNSSSFKLEFGNYPRSEVDASSRTLKPWEGRIYISE
SIO_010081: YIL172C
subclass of: SO_0000673
so part of: YIL172C
location: complement(16784..18553)
location: region:16784-18553:-1
so has part: feature:16784-18553:-1:exon

NP_012096.1
type: Protein
SIO_000068: ncbiprotein

S000001434
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:16784-18553:-1:exon

YIL171W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: HXT12
locus tag: YIL171W
gene synonym: HXT12
note: Possible pseudogene in strain S288C; YIL171W and the adjacent ORF, YIL170W/HXT12, together encode a non-functional member of the hexose transporter family
pseudo: true
so part of: sequence
location: 19515..19844
location: region:19515-19844:1
so has part: feature:19515-19844:1:exon

2827704
type: Gene
SIO_000068: ncbigene

S000001433
type: SGD
SIO_000068: sgd

position:19515:1
position: 19515
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:19844:1
position: 19844
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:19515-19844:1:exon

YIL171W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: HXT12
locus tag: YIL171W
gene synonym: HXT12
pseudo: true
SIO_010081: YIL171W
subclass of: SO_0000673
so part of: YIL171W
location: 19515..19844
location: region:19515-19844:1
so has part: feature:19515-19844:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:19515-19844:1:exon

YIL170W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HXT12
locus tag: YIL170W
note: Possible pseudogene in strain S288C; YIL170W/HXT12 and the adjacent ORF, YIL171W, together encode a non-functional member of the hexose transporter family
pseudo: true
so part of: sequence
location: 19847..21220
location: region:19847-21220:1
so has part: feature:19847-21220:1:exon

854636
type: Gene
SIO_000068: ncbigene

S000001432
type: SGD
SIO_000068: sgd

position:19847:1
position: 19847
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:21220:1
position: 21220
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:19847-21220:1:exon

YIL170W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HXT12
locus tag: YIL170W
pseudo: true
SIO_010081: YIL170W
subclass of: SO_0000673
so part of: YIL170W
location: 19847..21220
location: region:19847-21220:1
so has part: feature:19847-21220:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:19847-21220:1:exon

YIL169C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CSS1
locus tag: YIL169C
so part of: sequence
location: complement(<23119..>26106)
location: region:23119-26106:-1
so has part: feature:23119-26106:-1:exon
subclass of: SO_0000010

854637
type: Gene
SIO_000068: ncbigene

position:23119:-1
position: 23119
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:26106:-1
position: 26106
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:23119-26106:-1:exon

YIL169C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CSS1
locus tag: YIL169C
product: Css1p
transcript id: NM_001179517.1
SIO_010081: YIL169C
subclass of: SO_0000673
so part of: YIL169C
location: complement(<23119..>26106)
location: region:23119-26106:-1
so has part: feature:23119-26106:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:23119-26106:-1:exon

YIL169C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CSS1
locus tag: YIL169C
experiment: EXISTENCE:direct assay:GO:0005576 extracellular region [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
note: hypothetical protein, secreted when constitutively expressed; SWAT-GFP, seamless-GFP and mCherry fusion proteins localize to the cell periphery, SWAT-GFP fusion also localizes to the extracellular region, and mCherry fusion also localizes to the vacuole; S/T rich and highly similar to YOL155C, a putative glucan alpha-1,4-glucosidase; transcript is induced in both high and low pH environments; non-essential gene
codon start: 1
product: Css1p
translation: MFNRLNKFQAALALALYSQSALGQYYSNSTSISSNSSSTSVVSSSSGSVSISSSIAETSSSATDILSSITQSASSTSGVSSSVGPSSSSVVSSSVSQSSSSVSDVSSSVSQSSSSASDVSSSVSQSASSTSDVSSSVSQSSSSASDVSSSVSQSSSSASDVSSSVSQSASSASDVSSSVSQSASSTSDVSSSVSQSSSSASDVSSSVSQSSSSASDVSSSVSQSASSTSDVSSSVSQSASSTSGVSSSGSQSVSSASGSSSSFPQSTSSASTASGSATSNSLSSITSSASSASATASNSLSSSDGTIYLPTTTISGDLTLTGKVIATEGVVVAAGAKLTLLDGDKYSFSADLKVYGDLLVKKSKETYPGTEFDISGENFDVTGNFNAEESAATSASIYSFTPSSFDNSGDISLSLSKSKKGEVTFSPYSNSGAFSFSNAILNGGSVSGLQRRDDTEGSVNNGEINLDNGSTYVIVEPVSGKGTVNIISGNLYLHYPDTFTGQTVVFKGEGVLAVDPTETNATPIPVVGYTGKNQIAITADITALSYDGTTGVLTATQGNRQFSFAIGTGFSSSDFSVSEGIFAGAYAYYLNYNGVVATSAASSSTASGASASVTGSTSFGASVTGSTASTSFGASVTGSTASTSFGASVTGSTSVYTTTLDYVNATSTVVVSCSETTDSNGNVYTITTTVPCSSTTATITSCDETGCHVSTSTGAVVTETVSSKSYTTATVTHCDDNGCNTKTVTSECSKETSATTASPKSYTTVTVTHCDDNGCNTKTVTSEAPEATTTTTVSSQSYTTATVTHCDDNGCKTKTVTSEAPEATTTTVSPKTYTTATVTQCDDNGCSTKTVTSECPEETSATTTSPKSYTTVTVTHCDDNGCNTKTVTSEAPEATTTTVSPKTYTTATVTQCDDNGCSTKTVTSEAPKETSETSETSAAPKDIHYCHWLLNGDDNGCNVKIITSKIPEATSTVTQLVLLQSHTLLSLLRVLKQPH
SIO_010081: YIL169C
subclass of: SO_0000673
so part of: YIL169C
location: complement(23119..26106)
location: region:23119-26106:-1
so has part: feature:23119-26106:-1:exon

NP_012097.1
type: Protein
SIO_000068: ncbiprotein

S000001431
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:23119-26106:-1:exon

YIL167W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YIL168W
gene: SDL1
locus tag: YIL167W
gene synonym: YIL168W
pseudo: true
so part of: sequence
location: 29032..30048
location: region:29032-30048:1
so has part: feature:29032-30048:1:exon

854639
type: Gene
SIO_000068: ncbigene

position:29032:1
position: 29032
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:30048:1
position: 30048
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:29032-30048:1:exon

YIL167W
type: Miscellaneous Feature
subclass of: SO_0000001
RO_0002162: 559292
alternative label: YIL168W
gene: SDL1
locus tag: YIL167W
gene synonym: YIL168W
note: Blocked reading frame otherwise encoding L-serine dehydratase
pseudo: true
SIO_010081: YIL167W
subclass of: SO_0000673
so part of: YIL167W
location: 29032..30048
location: region:29032-30048:1
so has part: feature:29032-30048:1:exon

S000001429
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:29032-30048:1:exon

YIL166C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SOA1
locus tag: YIL166C
so part of: sequence
location: complement(<30938..>32566)
location: region:30938-32566:-1
so has part: feature:30938-32566:-1:exon
subclass of: SO_0000010

854640
type: Gene
SIO_000068: ncbigene

position:30938:-1
position: 30938
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:32566:-1
position: 32566
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:30938-32566:-1:exon

YIL166C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SOA1
locus tag: YIL166C
product: Soa1p
transcript id: NM_001179514.1
SIO_010081: YIL166C
subclass of: SO_0000673
so part of: YIL166C
location: complement(<30938..>32566)
location: region:30938-32566:-1
so has part: feature:30938-32566:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:30938-32566:-1:exon

YIL166C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SOA1
locus tag: YIL166C
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0000316 sulfite transport [PMID:28165463]
experiment: EXISTENCE:genetic interaction:GO:0008272 sulfate transport [PMID:28165463]
experiment: EXISTENCE:mutant phenotype:GO:0015116 sulfate transmembrane transporter activity [PMID:28165463]
experiment: EXISTENCE:mutant phenotype:GO:0072348 sulfur compound transport [PMID:28165463]
experiment: EXISTENCE:mutant phenotype:GO:1901682 sulfur compound transmembrane transporter activity [PMID:28165463]
note: Sulfonate and inorganic sulfur transporter; low affinity sulfate, high affinity sulfite, thiosulfite and major sulfonate transporter; functions as a an H+ symporter; similar to the allantoate permease (Dal5p) subfamily of the major facilitator superfamily; mRNA expression is elevated by sulfur limitation; non-essential gene
codon start: 1
product: Soa1p
translation: MSVQKEEYDIVEKAQLSVSAESLTSDSESISHNPFDDFHKAERWRKVYESSGYEGLSKFDPEFTWTKDEEKKLVRKMDLKIFLWVFIMFAFLDLIRKNIARAVSDNFIVDLKMNTNDYNLGQTVYLVIFLASELPGNLLSKRFGPERVIPVQIVLWSVICITQAGLKNRGQFIATRCLLGMVQGGFIPDNILYLSYYYTGAELTFRLSFFWCAIPLFQILGSLLASGIIEMRGIHNLAGWQYLFIIEGFLSLSVGVASFYLMRRGPTQTGESAFHKGKSLFTEYEEKIMVNRILRDDPSKGDMSNRQPVTFKEILYTLTEFDLWPLFIQGITAFISLQTVGSYLSLILKSLNYSTFLSNILAIPGQALLLINLPLAALLSRKLKEKSLCVGIANVWVLPFIVSLVALPTDTNPWIKYILLTGILGLPYTHSILAGWVSEISNSVRSRTVGTALYNMSAQVGAIIASNMYRNDDKPYYTRGNKILLGFTCFNICMAVATKFYYISRNKYKDRKWNSMTKEEQINYLDTTKDKGMKRLDYRFIH
SIO_010081: YIL166C
subclass of: SO_0000673
so part of: YIL166C
location: complement(30938..32566)
location: region:30938-32566:-1
so has part: feature:30938-32566:-1:exon

NP_012100.1
type: Protein
SIO_000068: ncbiprotein

S000001428
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:30938-32566:-1:exon

YIL165C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YIL165C
so part of: sequence
location: complement(<33718..>34077)
location: region:33718-34077:-1
so has part: feature:33718-34077:-1:exon
subclass of: SO_0000010

854641
type: Gene
SIO_000068: ncbigene

position:33718:-1
position: 33718
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:34077:-1
position: 34077
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:33718-34077:-1:exon

YIL165C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YIL165C
product: uncharacterized protein
transcript id: NM_001179513.1
SIO_010081: YIL165C
subclass of: SO_0000673
so part of: YIL165C
location: complement(<33718..>34077)
location: region:33718-34077:-1
so has part: feature:33718-34077:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:33718-34077:-1:exon

YIL165C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YIL165C
experiment: EXISTENCE:mutant phenotype:GO:0000422 autophagy of mitochondrion [PMID:19793921]
experiment: EXISTENCE:mutant phenotype:GO:0016236 macroautophagy [PMID:19793921]
note: hypothetical protein; mutant exhibits mitophagy defects; in closely related species and other S. cerevisiae strain backgrounds YIL165C and adjacent ORF, YIL164C, likely constitute a single ORF encoding a nitrilase gene
codon start: 1
product: uncharacterized protein
translation: MKNIAYEGRLFLISAVQFMPDATAMGFGEIIDQATGKRKLPGWPSADDNCINGGSVIIDPYGEIIAGPLLGQEGLLTAEINTDLIAEARFDLDPVGHYARGDVFQLTVNERSHDVKFTK
SIO_010081: YIL165C
subclass of: SO_0000673
so part of: YIL165C
location: complement(33718..34077)
location: region:33718-34077:-1
so has part: feature:33718-34077:-1:exon

NP_012101.1
type: Protein
SIO_000068: ncbiprotein

S000001427
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:33718-34077:-1:exon

YIL164C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: NIT1
locus tag: YIL164C
so part of: sequence
location: complement(<34087..>34686)
location: region:34087-34686:-1
so has part: feature:34087-34686:-1:exon
subclass of: SO_0000010

854642
type: Gene
SIO_000068: ncbigene

position:34087:-1
position: 34087
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:34686:-1
position: 34686
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:34087-34686:-1:exon

YIL164C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: NIT1
locus tag: YIL164C
product: Nit1p
transcript id: NM_001179512.1
SIO_010081: YIL164C
subclass of: SO_0000673
so part of: YIL164C
location: complement(<34087..>34686)
location: region:34087-34686:-1
so has part: feature:34087-34686:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:34087-34686:-1:exon

YIL164C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: NIT1
locus tag: YIL164C
note: Nitrilase; member of the nitrilase branch of the nitrilase superfamily; in closely related species and other S. cerevisiae strain backgrounds YIL164C and adjacent ORF, YIL165C, likely constitute a single ORF encoding a nitrilase gene
codon start: 1
product: Nit1p
translation: MAKHIVAALQIGSCPGSTKDTLKKILSYEKEIKESGAKLVVIPEATLGGYPKGSNFGVYLGYRLQEGREEYAKYLAEAIEIGNGEKYPEISQLCALSKATDASLCVGCIERDGTTLYCTMVYIDPKDGYVGKHRKLMPTAGERLIWGQGDGSTLPVVDTAAGKIGGAICWENMMPLLRYAMYKKGVEIWCAPTVDARPI
SIO_010081: YIL164C
subclass of: SO_0000673
so part of: YIL164C
location: complement(34087..34686)
location: region:34087-34686:-1
so has part: feature:34087-34686:-1:exon

NP_012102.1
type: Protein
SIO_000068: ncbiprotein

S000001426
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:34087-34686:-1:exon

YIL163C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YIL163C
so part of: sequence
location: complement(<36899..>37252)
location: region:36899-37252:-1
so has part: feature:36899-37252:-1:exon
subclass of: SO_0000010

854643
type: Gene
SIO_000068: ncbigene

position:36899:-1
position: 36899
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:37252:-1
position: 37252
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:36899-37252:-1:exon

YIL163C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YIL163C
product: uncharacterized protein
transcript id: NM_001270749.1
SIO_010081: YIL163C
subclass of: SO_0000673
so part of: YIL163C
location: complement(<36899..>37252)
location: region:36899-37252:-1
so has part: feature:36899-37252:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:36899-37252:-1:exon

YIL163C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YIL163C
note: hypothetical protein; mRNA identified as translated by ribosome profiling data
codon start: 1
product: uncharacterized protein
translation: MFLFRRKDYRIEIQKKKVVKSFFQMVYYRALRQHFCQTKSFKHSSKRNVSMMVIGKHRAYLKSLRHHIKGFIITFLVSFSRNLHGKTLDVGSINATRISSPPDNFLNWVFSFYSCSE
SIO_010081: YIL163C
subclass of: SO_0000673
so part of: YIL163C
location: complement(36899..37252)
location: region:36899-37252:-1
so has part: feature:36899-37252:-1:exon

NP_001257678.1
type: Protein
SIO_000068: ncbiprotein

S000001425
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:36899-37252:-1:exon

YIL162W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SUC2
locus tag: YIL162W
so part of: sequence
location: <37385..>38983
location: region:37385-38983:1
so has part: feature:37385-38983:1:exon
subclass of: SO_0000010

854644
type: Gene
SIO_000068: ncbigene

position:37385:1
position: 37385
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:38983:1
position: 38983
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:37385-38983:1:exon

YIL162W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SUC2
locus tag: YIL162W
product: beta-fructofuranosidase SUC2
transcript id: NM_001179510.1
SIO_010081: YIL162W
subclass of: SO_0000673
so part of: YIL162W
location: <37385..>38983
location: region:37385-38983:1
so has part: feature:37385-38983:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:37385-38983:1:exon

YIL162W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SUC2
locus tag: YIL162W
EC number: 3.2.1.26
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0004564 beta-fructofuranosidase activity [PMID:363706|PMID:3902817]
experiment: EXISTENCE:direct assay:GO:0005576 extracellular region [PMID:6341817]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:6341817]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005987 sucrose catabolic process [PMID:363706|PMID:3902817]
experiment: EXISTENCE:direct assay:GO:0051670 inulinase activity [PMID:23104410]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:1902927 inulin catabolic process [PMID:23104410]
experiment: EXISTENCE:mutant phenotype:GO:0004564 beta-fructofuranosidase activity [PMID:2834091]
experiment: EXISTENCE:mutant phenotype:GO:0005987 sucrose catabolic process [PMID:2834091]
experiment: EXISTENCE:mutant phenotype:GO:0010147 fructan catabolic process [PMID:23339519]
experiment: EXISTENCE:mutant phenotype:GO:0034484 raffinose catabolic process [PMID:23339519]
note: Invertase; sucrose hydrolyzing enzyme; a secreted, glycosylated form is regulated by glucose repression, and an intracellular, nonglycosylated enzyme is produced constitutively
codon start: 1
product: beta-fructofuranosidase SUC2
translation: MLLQAFLFLLAGFAAKISASMTNETSDRPLVHFTPNKGWMNDPNGLWYDEKDAKWHLYFQYNPNDTVWGTPLFWGHATSDDLTNWEDQPIAIAPKRNDSGAFSGSMVVDYNNTSGFFNDTIDPRQRCVAIWTYNTPESEEQYISYSLDGGYTFTEYQKNPVLAANSTQFRDPKVFWYEPSQKWIMTAAKSQDYKIEIYSSDDLKSWKLESAFANEGFLGYQYECPGLIEVPTEQDPSKSYWVMFISINPGAPAGGSFNQYFVGSFNGTHFEAFDNQSRVVDFGKDYYALQTFFNTDPTYGSALGIAWASNWEYSAFVPTNPWRSSMSLVRKFSLNTEYQANPETELINLKAEPILNISNAGPWSRFATNTTLTKANSYNVDLSNSTGTLEFELVYAVNTTQTISKSVFADLSLWFKGLEDPEEYLRMGFEVSASSFFLDRGNSKVKFVKENPYFTNRMSVNNQPFKSENDLSYYKVYGLLDQNILELYFNDGDVVSTNTYFMTTGNALGSVNMTTGVDNLFYIDKFQVREVK
SIO_010081: YIL162W
subclass of: SO_0000673
so part of: YIL162W
location: 37385..38983
location: region:37385-38983:1
so has part: feature:37385-38983:1:exon

NP_012104.1
type: Protein
SIO_000068: ncbiprotein

S000001424
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:37385-38983:1:exon

YIL161W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SMU2
locus tag: YIL161W
so part of: sequence
location: <39433..>40140
location: region:39433-40140:1
so has part: feature:39433-40140:1:exon
subclass of: SO_0000010

854645
type: Gene
SIO_000068: ncbigene

position:39433:1
position: 39433
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:40140:1
position: 40140
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:39433-40140:1:exon

YIL161W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SMU2
locus tag: YIL161W
product: Smu2p
transcript id: NM_001179509.1
SIO_010081: YIL161W
subclass of: SO_0000673
so part of: YIL161W
location: <39433..>40140
location: region:39433-40140:1
so has part: feature:39433-40140:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:39433-40140:1:exon

YIL161W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SMU2
locus tag: YIL161W
experiment: EXISTENCE:direct assay:GO:0005515 protein binding [PMID:36113412]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:36113412]
experiment: EXISTENCE:direct assay:GO:0070651 nonfunctional rRNA decay [PMID:36113412]
note: Protein involved in removal of stalled ribosomes; acts as cofactor for Fap1p and Fpr1p in ubiquitination of stalled monosomes and subsequent degradation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; mRNA is enriched in Scp160p-associated mRNPs; YIL161W is a non-essential gene
codon start: 1
product: Smu2p
translation: MDTKLSVTGAKKSQGKASGLGNEGTPIGNEESTNKAKNGNKKRNKNRNRNKKTETKEQNEPKPVTGGEEVRVEKSQAKNRRRKNNNGANKKNTLHYSKEINVEERKQIAKRQEEIEQCIHTLSDFKLFKKGKHVTSYGYRISPMTDSGKISLKILFNIPLDYPKAPIKLTMKSNEEVSSYMDTVIANFNWKARQLVKEDWRILSQINYLVSELEILKMENYKQIDKLRNSFYKTI
SIO_010081: YIL161W
subclass of: SO_0000673
so part of: YIL161W
location: 39433..40140
location: region:39433-40140:1
so has part: feature:39433-40140:1:exon

NP_012105.1
type: Protein
SIO_000068: ncbiprotein

S000001423
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:39433-40140:1:exon

YIL160C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: FOX3
alternative label: POX3
gene: POT1
locus tag: YIL160C
gene synonym: FOX3; POX3
so part of: sequence
location: complement(<40191..>41444)
location: region:40191-41444:-1
so has part: feature:40191-41444:-1:exon
subclass of: SO_0000010

854646
type: Gene
SIO_000068: ncbigene

position:40191:-1
position: 40191
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:41444:-1
position: 41444
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:40191-41444:-1:exon

YIL160C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: FOX3
alternative label: POX3
gene: POT1
locus tag: YIL160C
gene synonym: FOX3; POX3
product: acetyl-CoA C-acyltransferase
transcript id: NM_001179508.1
SIO_010081: YIL160C
subclass of: SO_0000673
so part of: YIL160C
location: complement(<40191..>41444)
location: region:40191-41444:-1
so has part: feature:40191-41444:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:40191-41444:-1:exon

YIL160C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: FOX3
alternative label: POX3
gene: POT1
locus tag: YIL160C
gene synonym: FOX3; POX3
EC number: 2.3.1.16
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:21124907]
experiment: EXISTENCE:direct assay:GO:0003988 acetyl-CoA C-acyltransferase activity [PMID:7754706]
experiment: EXISTENCE:direct assay:GO:0005758 mitochondrial intermembrane space [PMID:22984289]
experiment: EXISTENCE:direct assay:GO:0005777 peroxisome [PMID:19470242]
experiment: EXISTENCE:direct assay:GO:0005782 peroxisomal matrix [PMID:7754706|PMID:8125978]
experiment: EXISTENCE:mutant phenotype:GO:0005782 peroxisomal matrix [PMID:8125978]
experiment: EXISTENCE:mutant phenotype:GO:0006635 fatty acid beta-oxidation [PMID:12819196]
note: 3-ketoacyl-CoA thiolase with broad chain length specificity; cleaves 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA during beta-oxidation of fatty acids
codon start: 1
product: acetyl-CoA C-acyltransferase
translation: MSQRLQSIKDHLVESAMGKGESKRKNSLLEKRPEDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESMTNNYKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEFAANSYQKAYKAKNEGLFEDEILPIKLPDGSICQSDEGPRPNVTAESLSSIRPAFIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGARQVATILRELKKDQIGVVSMCIGTGMGAAAIFIKE
SIO_010081: YIL160C
subclass of: SO_0000673
so part of: YIL160C
location: complement(40191..41444)
location: region:40191-41444:-1
so has part: feature:40191-41444:-1:exon

NP_012106.1
type: Protein
SIO_000068: ncbiprotein

S000001422
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:40191-41444:-1:exon

YIL159W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: BNR1
locus tag: YIL159W
so part of: sequence
location: <41825..>45952
location: region:41825-45952:1
so has part: feature:41825-45952:1:exon
subclass of: SO_0000010

854647
type: Gene
SIO_000068: ncbigene

position:41825:1
position: 41825
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:45952:1
position: 45952
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:41825-45952:1:exon

YIL159W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: BNR1
locus tag: YIL159W
product: formin BNR1
transcript id: NM_001179507.1
SIO_010081: YIL159W
subclass of: SO_0000673
so part of: YIL159W
location: <41825..>45952
location: region:41825-45952:1
so has part: feature:41825-45952:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:41825-45952:1:exon

YIL159W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: BNR1
locus tag: YIL159W
experiment: EXISTENCE:direct assay:GO:0005522 profilin binding [PMID:15923184]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:9774458]
experiment: EXISTENCE:direct assay:GO:0032153 cell division site [PMID:26771880]
experiment: EXISTENCE:direct assay:GO:0045010 actin nucleation [PMID:30076201]
experiment: EXISTENCE:direct assay:GO:0051016 barbed-end actin filament capping [PMID:15923184]
experiment: EXISTENCE:direct assay:GO:0051017 actin filament bundle assembly [PMID:15923184]
experiment: EXISTENCE:direct assay:GO:0070649 formin-nucleated actin cable assembly [PMID:15923184]
experiment: EXISTENCE:genetic interaction:GO:0051017 actin filament bundle assembly [PMID:23671312]
experiment: EXISTENCE:genetic interaction:GO:0070649 formin-nucleated actin cable assembly [PMID:11740491]
experiment: EXISTENCE:genetic interaction:GO:1903475 mitotic actomyosin contractile ring assembly [PMID:12419188]
experiment: EXISTENCE:genetic interaction:GO:2000251 positive regulation of actin cytoskeleton reorganization [PMID:17237521]
experiment: EXISTENCE:mutant phenotype:GO:0005522 profilin binding [PMID:15923184]
experiment: EXISTENCE:mutant phenotype:GO:0051017 actin filament bundle assembly [PMID:23671312]
experiment: EXISTENCE:mutant phenotype:GO:0070649 formin-nucleated actin cable assembly [PMID:15371545]
note: Formin; nucleates the formation of linear actin filaments; involved in processes such as budding and mitotic spindle orientation which require the formation of polarized actin cables; activity is regulated by Hof1p and by the Bud14p-Kel1p-Kel2p complex; dephosphorylated and delocalized from the division site in a Glc7p/Ref2p-dependent manner; functionally redundant with BNI1
codon start: 1
product: formin BNR1
translation: MDSSPNKKTYRYPRRSLSLHARDRVSEARKLEELNLNDGLVAAGLQLVGVALEKQGTGSHIYMKQKNFSANDVSSSPMVSEEVNGSEMDFNPKCMPQDASLVERMFDELLKDGTFFWGAAYKNLQNISLRRKWLLICKIRSSNHWGKKKVTSSTTYSTHLATNELAENAHFLDGLVRNLSTGGMKLSKALYKLEKFLRKQSFLQLFLKDEIYLTTLIEKTLPLISKELQFVYLRCFKILMNNPLARIRALHSEPLIRWFTELLTDQNSNLKCQLLSMELLLLLTYVEGSTGCELIWDQLSILFTDWLEWFDKILADDIAIHSSLYLNWNQLKIDYSTTFLLLINSILQGFNNKTALEILNFLKKNNIHNTITFLELAYKDDPNSVVIMEQIKQFKSKESAIFDSMIKTTNDTNSLHPTKDIARIESEPLCLENCLLLKAKDSPVEAPINEIIQSLWKILDSQKPYSESIKLLKLINSLLFYLIDSFQVSTNPSFDETLESAENVDYVFQDSVNKLLDSLQSDEIARRAVTEIDDLNAKISHLNEKLNLVENHDKDHLIAKLDESESLISLKTKEIENLKLQLKATKKRLDQITTHQRLYDQPPSLASSNLSIAGSIIKNNSHGNIIFQNLAKKQQQQQKISLPKRSTSLLKSKRVTSLSSYLTDANNENESQNESEDKSKDSLFQRSTSTINFNIPSMKNITNMQNVSLNSILSELEFSNSLGTQPNYQSSPVLSSVSSSPKLFPRLSSDSLDNGIQLVPEVVKLPQLPPPPPPPPPPPLPQSLLTEAEAKPDGVSCIAAPAPPPLPDLFKTKTCGAVPPPPPPPPLPESLSMNKGPSNHDLVTPPAPPLPNGLLSSSSVSINPTTTDLKPPPTEKRLKQIHWDKVEDIKDTLWEDTFQRQETIKELQTDGIFSQIEDIFKMKSPTKIANKRNAESSIALSSNNGKSSNELKKISFLSRDLAQQFGINLHMFSQLSDMEFVMKVLNCDNDIVQNVNILKFFCKEELVNIPKSMLNKYEPYSQGKDGKAVSDLQRADRIFLELCINLRFYWNARSKSLLTLSTYERDYYDLIFKLQKIDDAISHLNRSPKFKSLMFIITEIGNHMNKRIVKGIKLKSLTKLAFVRSSIDQNVSFLHFIEKVIRIKYPDIYGFVDDLKNIEDLGKISLEHVESECHEFHKKIEDLVTQFQVGKLSKEENLDPRDQIIKKVKFKINRAKTKSELLIGQCKLTLIDLNKLMKYYGEDPKDKESKNEFFQPFIEFLAMFKKCAKENIEKEEMERVYEQRKSLLDMRTSSNKKSNGSDENDGEKVNRDAVDLLISKLREVKKDPEPLRRRKSTKLNEIAINVHEGDVKTRKDEDHVLLERTHAMLNDIQNI
SIO_010081: YIL159W
subclass of: SO_0000673
so part of: YIL159W
location: 41825..45952
location: region:41825-45952:1
so has part: feature:41825-45952:1:exon

NP_012107.1
type: Protein
SIO_000068: ncbiprotein

S000001421
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:41825-45952:1:exon

YIL158W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: AIM20
locus tag: YIL158W
so part of: sequence
location: <46201..>46815
location: region:46201-46815:1
so has part: feature:46201-46815:1:exon
subclass of: SO_0000010

854648
type: Gene
SIO_000068: ncbigene

position:46201:1
position: 46201
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:46815:1
position: 46815
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:46201-46815:1:exon

YIL158W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: AIM20
locus tag: YIL158W
product: Aim20p
transcript id: NM_001179506.3
SIO_010081: YIL158W
subclass of: SO_0000673
so part of: YIL158W
location: <46201..>46815
location: region:46201-46815:1
so has part: feature:46201-46815:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:46201-46815:1:exon

YIL158W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: AIM20
locus tag: YIL158W
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22842922]
note: hypothetical protein; overexpression causes cell cycle delay or arrest; green fluorescent protein (GFP)-fusion protein localizes to vacuole; null mutant displays elevated frequency of mitochondrial genome loss; relocalizes from nucleus to cytoplasm upon DNA replication stress; AIM20 has a paralog, SKG1, that arose from the whole genome duplication
codon start: 1
product: Aim20p
translation: MGNVSVAVGTAVGIPIAVGVIIALIFWCKLQRRYKKEEIRDADLEKMVMEEVAVSVYDGFKAEINSSSEASTINEKEANQDLKPCQEKTAKAGYTPAYRRQLNASMGTLRPKKQSTAYTNVPVIFSGEKVNYGMVRDPSYSFMYPLTLSRKETSSLRSASTSNLSSSTENTALHEEIKLDDPYENDFTNYTVNKREFIDSLRPH
SIO_010081: YIL158W
subclass of: SO_0000673
so part of: YIL158W
location: 46201..46815
location: region:46201-46815:1
so has part: feature:46201-46815:1:exon

NP_012108.3
type: Protein
SIO_000068: ncbiprotein

S000001420
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:46201-46815:1:exon

YIL157C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: COA1
locus tag: YIL157C
so part of: sequence
location: complement(<46949..>47542)
location: region:46949-47542:-1
so has part: feature:46949-47542:-1:exon
subclass of: SO_0000010

854649
type: Gene
SIO_000068: ncbigene

position:46949:-1
position: 46949
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:47542:-1
position: 47542
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:46949-47542:-1:exon

YIL157C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: COA1
locus tag: YIL157C
product: Coa1p
transcript id: NM_001179505.1
SIO_010081: YIL157C
subclass of: SO_0000673
so part of: YIL157C
location: complement(<46949..>47542)
location: region:46949-47542:-1
so has part: feature:46949-47542:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:46949-47542:-1:exon

YIL157C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: COA1
locus tag: YIL157C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095|PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005743 mitochondrial inner membrane [PMID:17882259]
experiment: EXISTENCE:direct assay:GO:0031966 mitochondrial membrane [PMID:17882260]
experiment: EXISTENCE:mutant phenotype:GO:0033617 mitochondrial cytochrome c oxidase assembly [PMID:17882259|PMID:17882260]
experiment: EXISTENCE:physical interaction:GO:0033617 mitochondrial cytochrome c oxidase assembly [PMID:17882259]
note: Mitochondrial inner membrane protein; required for assembly of the cytochrome c oxidase complex (complex IV); interacts with complex IV assembly factor Shy1p during the early stages of assembly
codon start: 1
product: Coa1p
translation: MMLRLVTKGLPKVTPSAAKAVLVRGSLLHSFSTSARFNNSVAEDEAKIVLKDKNRPLRIDRELPDPTTERRKRIAGFLLFSVAIGSALSLIFNYEKTESPIISNTLYYIRRSPATKNILGESIEFDGIIPWVYGELNSVKGRINITFYIKGDKNVTGTVRLVADRNTHDEEFLIHEWSVTAAGQKIDLLAENTKTPI
SIO_010081: YIL157C
subclass of: SO_0000673
so part of: YIL157C
location: complement(46949..47542)
location: region:46949-47542:-1
so has part: feature:46949-47542:-1:exon

NP_012109.1
type: Protein
SIO_000068: ncbiprotein

S000001419
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:46949-47542:-1:exon

YIL156W-B
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MCO8
locus tag: YIL156W-B
so part of: sequence
location: <47690..>47973
location: region:47690-47973:1
so has part: feature:47690-47973:1:exon
subclass of: SO_0000010

3628034
type: Gene
SIO_000068: ncbigene

position:47690:1
position: 47690
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:47973:1
position: 47973
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:47690-47973:1:exon

YIL156W-B
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MCO8
locus tag: YIL156W-B
product: Mco8p
transcript id: NM_001184521.1
SIO_010081: YIL156W-B
subclass of: SO_0000673
so part of: YIL156W-B
location: join(<47690..47698,47761..>47973)
location: region:47690-47973:1
so has part: feature:47690-47698:1:exon
so has part: feature:47761-47973:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:47690-47698:1:exon

position:47698:1
position: 47698
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:47761-47973:1:exon

position:47761:1
position: 47761
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YIL156W-B
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MCO8
locus tag: YIL156W-B
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
note: Mitochondrial hypothetical protein; originally identified based on homology to Ashbya gossypii and other related yeasts; SWAT-GFP and mCherry fusion proteins localize to the vacuole, while SWAT-GFP fusion also localizes to the endoplasmic reticulum
codon start: 1
product: Mco8p
translation: MTLVGKLVHISIDLVLVSTCLAGIKRNTGLTPKLETLDNQTMRNYMKRYLNLGESVYDYSVATCGSSTYFARK
SIO_010081: YIL156W-B
subclass of: SO_0000673
so part of: YIL156W-B
location: join(47690..47698,47761..47973)
location: region:47690-47973:1
so has part: feature:47690-47698:1:exon
so has part: feature:47761-47973:1:exon

NP_001027534.1
type: Protein
SIO_000068: ncbiprotein

S000028511
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:47690-47698:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:47761-47973:1:exon

YIL156W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: UBP7
locus tag: YIL156W
so part of: sequence
location: <48091..>51306
location: region:48091-51306:1
so has part: feature:48091-51306:1:exon
subclass of: SO_0000010

854650
type: Gene
SIO_000068: ncbigene

position:48091:1
position: 48091
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:51306:1
position: 51306
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:48091-51306:1:exon

YIL156W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: UBP7
locus tag: YIL156W
product: ubiquitin-specific protease UBP7
transcript id: NM_001179504.1
SIO_010081: YIL156W
subclass of: SO_0000673
so part of: YIL156W
location: <48091..>51306
location: region:48091-51306:1
so has part: feature:48091-51306:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:48091-51306:1:exon

YIL156W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: UBP7
locus tag: YIL156W
EC number: 3.4.19.12
experiment: EXISTENCE:curator inference:GO:0005737 cytoplasm [PMID:8982460]
experiment: EXISTENCE:direct assay:GO:0004843 cysteine-type deubiquitinase activity [PMID:24746795]
experiment: EXISTENCE:direct assay:GO:0016579 protein deubiquitination [PMID:24746795]
note: Ubiquitin-specific protease that cleaves ubiquitin-protein fusions; involved in cell cycle progression through S phase; UBP7 has a paralog, UBP11, that arose from the whole genome duplication
codon start: 1
product: ubiquitin-specific protease UBP7
translation: MLDDDKGTAMHPHITPFTPEYSNELLRRVQDLYHEDIKHYYPQLKLEKLLDLLEHTEYLFELYLDSIHHDRPNDALTAFIIGCYYVFLIIPQSLQFQTRNKSYSIYTDLKKMYENEMNMTNVVLMVKKEIGVVLDESVKHGAGIEHRITKKRAFSVPADDLSGQVASLSLDTAAPQDHGLKGTFTEDDAEQSSPVWTAPNLEPNDQLKLALLPEVIPTPAFREPERKTSVPVRPSVLLEDVPSIYHEDDTSFASLNPPFREITADRSVTHRKDSYHSVYMVDSGNLKEDNDDLFNVENDGFIQSLDILQKQSIITAPELFSILSNRVEREKVLLIDLRIPQRSAINHIVAPNLVNVDPNLLWDKQTNTPIYKDDILEHLLKENENFINRNKFDYIVYYTDVKTFMTINFDYAFIFFYLMLTSQKTPLTTVPTTLLGGYEKWKKTLHSYAQEYHISIEDYLYRPYSQKARLQQEQQQQQQQPDSQDSFSAKESSTKVPEPPSWKPPDLPIRLRKRPPPPPPVSMPTTPEIPPPLPPKIMVHSQVSSISRKPPIPAKQHVKKEQLNSNEIIQRKRQHQHQHYDQQILQPQRAYNIPTIERSPNVYVSLSITGLRNLGNTCYINSMIQCLFAAKTFRTLFISSKYKSYLQPIRSNGSHYSPKLSNSLSMLFNKMYLNGGCSVVPTGFLKVINQLRPDLKIPDDQQDTQEFLMILLDRLHDELSDQQHVANDYPNLLLYNADALKVSNNEYKHWFDKNVIGNGISPIDDIFQGQMENSLQCKRCGYTTFNYSTFYVLSLAIPRRSMKLSKLGRSTEKRVKLEDCINMFTSDEVLSGENAWDCPRCGPTASVSTSVSALENEPSIVKSKKKKSRFFTLHTGTKRRHLDFFGDGITEGHNSNNNNTTIFERERSRSPFRMLGGSGKRSSSSTPFSTGGNDSNNSSDYKNKKLTTVKTINFVTLPKILVIHLSRFYYDLTKKNNTVVTYPLILNIILKNNDTMKYKLFGVVNHTGTLISGHYTSLVNKDLEHNVNIGRSKWYYFDDEVVKADRKHGSDKNLKISSSDVYVLFYERVYD
SIO_010081: YIL156W
subclass of: SO_0000673
so part of: YIL156W
location: 48091..51306
location: region:48091-51306:1
so has part: feature:48091-51306:1:exon

NP_012110.1
type: Protein
SIO_000068: ncbiprotein

S000001418
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:48091-51306:1:exon

YIL155C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GUT2
locus tag: YIL155C
so part of: sequence
location: complement(<51759..>53708)
location: region:51759-53708:-1
so has part: feature:51759-53708:-1:exon
subclass of: SO_0000010

854651
type: Gene
SIO_000068: ncbigene

position:51759:-1
position: 51759
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:53708:-1
position: 53708
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:51759-53708:-1:exon

YIL155C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GUT2
locus tag: YIL155C
product: glycerol-3-phosphate dehydrogenase
transcript id: NM_001179503.1
SIO_010081: YIL155C
subclass of: SO_0000673
so part of: YIL155C
location: complement(<51759..>53708)
location: region:51759-53708:-1
so has part: feature:51759-53708:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:51759-53708:-1:exon

YIL155C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GUT2
locus tag: YIL155C
EC number: 1.1.5.3
experiment: EXISTENCE:direct assay:GO:0004368 glycerol-3-phosphate dehydrogenase (quinone) activity [PMID:12032156]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:11502169|PMID:14576278|PMID:24769239|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005741 mitochondrial outer membrane [PMID:16689936]
experiment: EXISTENCE:direct assay:GO:0006116 NADH oxidation [PMID:12032156]
experiment: EXISTENCE:mutant phenotype:GO:0004368 glycerol-3-phosphate dehydrogenase (quinone) activity [PMID:8256521]
experiment: EXISTENCE:mutant phenotype:GO:0005739 mitochondrion [PMID:8256521]
experiment: EXISTENCE:mutant phenotype:GO:0006071 glycerol metabolic process [PMID:8256521]
note: Mitochondrial glycerol-3-phosphate dehydrogenase; expression is repressed by both glucose and cAMP and derepressed by non-fermentable carbon sources in a Snf1p, Rsf1p, Hap2/3/4/5 complex dependent manner
codon start: 1
product: glycerol-3-phosphate dehydrogenase
translation: MFSVTRRRAAGAAAAMATATGTLYWMTSQGDRPLVHNDPSYMVQFPTAAPPQVSRRDLLDRLAKTHQFDVLIIGGGATGTGCALDAATRGLNVALVEKGDFASGTSSKSTKMIHGGVRYLEKAFWEFSKAQLDLVIEALNERKHLINTAPHLCTVLPILIPIYSTWQVPYIYMGCKFYDFFAGSQNLKKSYLLSKSATVEKAPMLTTDNLKASLVYHDGSFNDSRLNATLAITAVENGATVLNYVEVQKLIKDPTSGKVIGAEARDVETNELVRINAKCVVNATGPYSDAILQMDRNPSGLPDSPLNDNSKIKSTFNQIAVMDPKMVIPSIGVHIVLPSFYCPKDMGLLDVRTSDGRVMFFLPWQGKVLAGTTDIPLKQVPENPMPTEADIQDILKELQHYIEFPVKREDVLSAWAGVRPLVRDPRTIPADGKKGSATQGVVRSHFLFTSDNGLITIAGGKWTTYRQMAEETVDKVVEVGGFHNLKPCHTRDIKLAGAEEWTQNYVALLAQNYHLSSKMSNYLVQNYGTRSSIICEFFKESMENKLPLSLADKENNVIYSSEENNLVNFDTFRYPFTIGELKYSMQYEYCRTPLDFLLRRTRFAFLDAKEALNAVHATVKVMGDEFNWSEKKRQWELEKTVNFIKTFGV
SIO_010081: YIL155C
subclass of: SO_0000673
so part of: YIL155C
location: complement(51759..53708)
location: region:51759-53708:-1
so has part: feature:51759-53708:-1:exon

NP_012111.1
type: Protein
SIO_000068: ncbiprotein

S000001417
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:51759-53708:-1:exon

YIL154C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: IMP2
gene: IMP21
locus tag: YIL154C
gene synonym: IMP2
so part of: sequence
location: complement(<53981..>55021)
location: region:53981-55021:-1
so has part: feature:53981-55021:-1:exon
subclass of: SO_0000010

854652
type: Gene
SIO_000068: ncbigene

position:53981:-1
position: 53981
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:55021:-1
position: 55021
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:53981-55021:-1:exon

YIL154C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: IMP2
gene: IMP21
locus tag: YIL154C
gene synonym: IMP2
product: Imp21p
transcript id: NM_001179502.3
SIO_010081: YIL154C
subclass of: SO_0000673
so part of: YIL154C
location: complement(<53981..>55021)
location: region:53981-55021:-1
so has part: feature:53981-55021:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:53981-55021:-1:exon

YIL154C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: IMP2
gene: IMP21
locus tag: YIL154C
gene synonym: IMP2
experiment: EXISTENCE:direct assay:GO:0003713 transcription coactivator activity [PMID:8628275]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0000429 carbon catabolite regulation of transcription from RNA polymerase II promoter [PMID:7496532]
note: Transcriptional activator involved in maintenance of ion homeostasis; also involved in protection against DNA damage caused by bleomycin and other oxidants; contains a C-terminal leucine-rich repeat
codon start: 1
product: Imp21p
translation: MQKSILLTKPDGTQSNLHSIKTETPTTVEFDSEQMERGHRERGRSKKKRGERDSNVSSLSRSRSRASSRSRVREEEFLKWTVLRQDPSMRLRVVDVDSEEEGEGNDEDDDDGDGDDMDEEESDEEQVSDIENDLEIDEEFHYDLGMKVLPNFCTSINEVLDSSKPWIAKYEISIRGHENEDVSLEQLDGGYVRAMQLLTKGAGAEAGNQRSFILYTDLSSESTYALTYLMGAAVNQGDTVYIVHWEPSKPTDDSQMFANVARIRKHVMHLFDCVAGVLDDLDVVVLSLTHPYPKHLLNEMIHGLKPVALCCSLSVILSTLQNFVCSVPILAVRKKLKRAKRKGISE
SIO_010081: YIL154C
subclass of: SO_0000673
so part of: YIL154C
location: complement(53981..55021)
location: region:53981-55021:-1
so has part: feature:53981-55021:-1:exon

NP_012112.3
type: Protein
SIO_000068: ncbiprotein

S000001416
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:53981-55021:-1:exon

YIL153W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YPA1
gene: RRD1
locus tag: YIL153W
gene synonym: YPA1
so part of: sequence
location: <55198..>56379
location: region:55198-56379:1
so has part: feature:55198-56379:1:exon
subclass of: SO_0000010

854653
type: Gene
SIO_000068: ncbigene

position:55198:1
position: 55198
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:56379:1
position: 56379
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:55198-56379:1:exon

YIL153W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YPA1
gene: RRD1
locus tag: YIL153W
gene synonym: YPA1
product: peptidylprolyl isomerase RRD1
transcript id: NM_001179501.1
SIO_010081: YIL153W
subclass of: SO_0000673
so part of: YIL153W
location: <55198..>56379
location: region:55198-56379:1
so has part: feature:55198-56379:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:55198-56379:1:exon

YIL153W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YPA1
gene: RRD1
locus tag: YIL153W
gene synonym: YPA1
EC number: 5.2.1.8
experiment: EXISTENCE:direct assay:GO:0000785 chromatin [PMID:21129186]
experiment: EXISTENCE:direct assay:GO:0003755 peptidyl-prolyl cis-trans isomerase activity [PMID:16380387]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:15150670]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:15150670]
experiment: EXISTENCE:mutant phenotype:GO:0006281 DNA repair [PMID:9705277|PMID:15150670]
experiment: EXISTENCE:mutant phenotype:GO:0006357 regulation of transcription by RNA polymerase II [PMID:21129186]
experiment: EXISTENCE:mutant phenotype:GO:0006914 autophagy [PMID:31962153]
experiment: EXISTENCE:mutant phenotype:GO:0006970 response to osmotic stress [PMID:10660069]
experiment: EXISTENCE:mutant phenotype:GO:0007052 mitotic spindle organization [PMID:11262194]
experiment: EXISTENCE:mutant phenotype:GO:0019888 protein phosphatase regulator activity [PMID:12952889]
experiment: EXISTENCE:physical interaction:GO:0000082 G1/S transition of mitotic cell cycle [PMID:11134337]
experiment: EXISTENCE:physical interaction:GO:0006357 regulation of transcription by RNA polymerase II [PMID:21129186]
note: Peptidyl-prolyl cis/trans-isomerase; activator of the phosphotyrosyl phosphatase activity of PP2A; involved in G1 phase progression, microtubule dynamics, bud morphogenesis and DNA repair; required for rapid reduction of Sgs1p levels in response to rapamycin; subunit of the Tap42p-Sit4p-Rrd1p complex; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress
codon start: 1
product: peptidylprolyl isomerase RRD1
translation: MSLDRVDWPHATFSTPVKRIFDTQTTLDFQSSLAIHRIKYHLHKYTTLISHCSDPDPHATASSIAMVNGLMGVLDKLAHLIDETPPLPGPRRYGNLACREWHHKLDERLPQWLQEMLPSEYHEVVPELQYYLGNSFGSSTRLDYGTGHELSFMATVAALDMLGMFPHMRGADVFLLFNKYYTIMRRLILTYTLEPAGSHGVWGLDDHFHLVYILGSSQWQLLDAQAPLQPREILDKSLVREYKDTNFYCQGINFINEVKMGPFEEHSPILYDIAVTVPRWSKVCKGLLKMYSVEVLKKFPVVQHFWFGTGFFPWVNIQNGTDLPVFEEKEEESIEQANAGSPGREQTSTRFPTSTSMPPPGVPPSGNNINYLLSHQNQSHRNQTSFSRDRLRR
SIO_010081: YIL153W
subclass of: SO_0000673
so part of: YIL153W
location: 55198..56379
location: region:55198-56379:1
so has part: feature:55198-56379:1:exon

NP_012113.1
type: Protein
SIO_000068: ncbiprotein

S000001415
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:55198-56379:1:exon

YIL152W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: VPR1
locus tag: YIL152W
so part of: sequence
location: <56545..>57252
location: region:56545-57252:1
so has part: feature:56545-57252:1:exon
subclass of: SO_0000010

854654
type: Gene
SIO_000068: ncbigene

position:56545:1
position: 56545
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:57252:1
position: 57252
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:56545-57252:1:exon

YIL152W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: VPR1
locus tag: YIL152W
product: Vpr1p
transcript id: NM_001179500.1
SIO_010081: YIL152W
subclass of: SO_0000673
so part of: YIL152W
location: <56545..>57252
location: region:56545-57252:1
so has part: feature:56545-57252:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:56545-57252:1:exon

YIL152W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: VPR1
locus tag: YIL152W
codon start: 1
product: Vpr1p
translation: MSHKRRGLVIYQDQKQQQQHPPGQSLSSISWSPTRRPHHPLKQQSTNSFSEILSKSSVQPNVQHDGNHMPISLLVLKQEHHKQQQQQQQRQNIRSQNSTPPLRQLVQESQWTSSASNSSLKKQEKQPQTFYNTDSKLVSQLHSSVKDLDAIIQTHKPKFDTIIRDFSQATILSSNELLIKLPKDQTIILHSRAPKINAEWLQNKVNDPSASLVIDSRSFLTLCNNIKWYLHWKFI
SIO_010081: YIL152W
subclass of: SO_0000673
so part of: YIL152W
location: 56545..57252
location: region:56545-57252:1
so has part: feature:56545-57252:1:exon

NP_012114.1
type: Protein
SIO_000068: ncbiprotein

S000001414
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:56545-57252:1:exon

YIL151C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ESL1
locus tag: YIL151C
so part of: sequence
location: complement(<57338..>60694)
location: region:57338-60694:-1
so has part: feature:57338-60694:-1:exon
subclass of: SO_0000010

854655
type: Gene
SIO_000068: ncbigene

position:57338:-1
position: 57338
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:60694:-1
position: 60694
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:57338-60694:-1:exon

YIL151C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ESL1
locus tag: YIL151C
product: Esl1p
transcript id: NM_001179499.1
SIO_010081: YIL151C
subclass of: SO_0000673
so part of: YIL151C
location: complement(<57338..>60694)
location: region:57338-60694:-1
so has part: feature:57338-60694:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:57338-60694:-1:exon

YIL151C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ESL1
locus tag: YIL151C
note: hEST1A/B (SMG5/6)-like protein; contributes to environment-sensing adaptive gene expression responses; Esl1p and Esl2p contain a 14-3-3-like domain and a putative PilT N-terminus ribonuclease domain; ESL1 has a paralog, ESL2, that arose from the whole genome duplication
codon start: 1
product: Esl1p
translation: MVDLMVPANDDPSNETDYSRSNNNHTHIVSDMRPTSAAFLHQKRHSSSSHNDTPESSFAKRRVPGIVDPVGKGFIDGITNSQISAQNTPSKTDDASRRPSISRKVMESTPQVKTSSIPTMDVPKSPYYVNRTMLARNMKVVSRDTYEDNANPQMRADEPLVASNGIYSNSQPQSQVTLSDIRRAPVVAASPPPMIRQLPSAQPNQTFIKKLQEIYKIIVVQETELQQRCLYLTTSQTTELKSLWAIYRLNTELIKNYINFIITALLTTQPINDLIMGQEILDIYRIEKRLWVYGIITFLDVLKNFSNFMDPEVCCQFIIYAFISVSNMLEDIPLKYSILWRQRLGDLSRMAISLYPSGFIDWRLSAEYWYTESMKYIYGCGKLYYHIATVQQNSLEAFVNLGKSVFCQDPFTPSQQTLQLLIENIYQSAFIDRSSGSANNNEIAHRNSQLIDYLKHTEVMLLPSFLENMDLQHVVLMYFKDKFGKDFNGNDVFDTKDMFCQNPESLRYYFRHAPAFAESQLLQLIGFGNPKNPFALLFQLPKYLKLKKDKREKKRSEATETSSYTDPFDVQISSESYFQNIDALNSSFNDIPTNLNIWLDSLNHINMTSIQCSIHVLTKFLHAPLVVALPHFLTWLHFIVAILKKLEMVNSKQVVAFWIHFLRRTMPWNSIVTLGNVLVCYMLDNLHPFLKKELEKFYSLELDDLIEYYNENENLPEIWKCWGTLWFDAIKKCDVMEIPGVQDHLFFDSPLDGIVFDEKDEVGEKFWMRSVRAVLLLKGIAKKFPDLGLKVSFQASVFCRRNDIPPDYFLKNLTFKLDAYDEDNYNDNNELDDLYDTIEINEEIEAVNMDPQATPNLSVVSGESIFEYTGYTRLAPDYHCFDKNGGFNSAFIYSQWSNVGNGVTLDVSGESIYDVANNNLSLHWEKIFFDKIAAASKGSDENYNCTLYFVIDATSWLRHFAHIFKLAKNNTLKFAICLTTFQELRYLRGSKDDTVVEAATRSVITIRQLYDEKKIIPMRFTGNIATHVEENLEFEEQITWKTHVDEFVIDAIAKLNQRFQAERLTDENKNKGKEFAVLVTDDDNMNQKAKDRMIKTCNTKYLFSLGSKLGINSGLCTN
SIO_010081: YIL151C
subclass of: SO_0000673
so part of: YIL151C
location: complement(57338..60694)
location: region:57338-60694:-1
so has part: feature:57338-60694:-1:exon

NP_012115.1
type: Protein
SIO_000068: ncbiprotein

S000001413
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:57338-60694:-1:exon

YIL150C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: DNA43
gene: MCM10
locus tag: YIL150C
gene synonym: DNA43
so part of: sequence
location: complement(<61013..>62728)
location: region:61013-62728:-1
so has part: feature:61013-62728:-1:exon
subclass of: SO_0000010

854656
type: Gene
SIO_000068: ncbigene

position:61013:-1
position: 61013
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:62728:-1
position: 62728
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:61013-62728:-1:exon

YIL150C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: DNA43
gene: MCM10
locus tag: YIL150C
gene synonym: DNA43
product: Mcm10p
transcript id: NM_001179498.1
SIO_010081: YIL150C
subclass of: SO_0000673
so part of: YIL150C
location: complement(<61013..>62728)
location: region:61013-62728:-1
so has part: feature:61013-62728:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:61013-62728:-1:exon

YIL150C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: DNA43
gene: MCM10
locus tag: YIL150C
gene synonym: DNA43
experiment: EXISTENCE:direct assay:GO:0003688 DNA replication origin binding [PMID:15494305|PMID:10783164]
experiment: EXISTENCE:direct assay:GO:0003690 double-stranded DNA binding [PMID:19605346]
experiment: EXISTENCE:direct assay:GO:0003697 single-stranded DNA binding [PMID:19605346|PMID:27751725]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:11168584|PMID:13680157|PMID:9154825]
experiment: EXISTENCE:direct assay:GO:0031298 replication fork protection complex [PMID:16531994]
experiment: EXISTENCE:genetic interaction:GO:0006270 DNA replication initiation [PMID:10783164]
experiment: EXISTENCE:genetic interaction:GO:0006271 DNA strand elongation involved in DNA replication [PMID:10783164|PMID:11168584]
experiment: EXISTENCE:mutant phenotype:GO:0000727 double-strand break repair via break-induced replication [PMID:20516198]
experiment: EXISTENCE:mutant phenotype:GO:0005657 replication fork [PMID:15494305]
experiment: EXISTENCE:mutant phenotype:GO:0006270 DNA replication initiation [PMID:10783164|PMID:9154825]
experiment: EXISTENCE:mutant phenotype:GO:0006271 DNA strand elongation involved in DNA replication [PMID:10783164|PMID:11168584|PMID:9154825]
experiment: EXISTENCE:mutant phenotype:GO:0030466 silent mating-type cassette heterochromatin formation [PMID:16085704|PMID:16328881]
experiment: EXISTENCE:mutant phenotype:GO:0031509 subtelomeric heterochromatin formation [PMID:16085704]
note: Essential chromatin-associated protein; involved in initiation of DNA replication; required for association of MCM2-7 complex with replication origins; required to stabilize catalytic subunit of DNA polymerase-alpha; coordinates function of replication fork helicase; self-associates through its N-terminal domain
codon start: 1
product: Mcm10p
translation: MNDPREILAVDPYNNITSDEEDEQAIARELEFMERKRQALVERLKRKQEFKKPQDPNFEAIEVPQSPTKNRVKVGSHNATQQGTKFEGSNINEVRLSQLQQQPKPPASTTTYFMEKFQNAKKNEDKQIAKFESMMNARVHTFSTDEKKYVPIITNELESFSNLWVKKRYIPEDDLKRALHEIKILRLGKLFAKIRPPKFQEPEYANWATVGLISHKSDIKFTSSEKPVKFFMFTITDFQHTLDVYIFGKKGVERYYNLRLGDVIAILNPEVLPWRPSGRGNFIKSFNLRISHDFKCILEIGSSRDLGWCPIVNKKTHKKCGSPINISLHKCCDYHREVQFRGTSAKRIELNGGYALGAPTKVDSQPSLYKAKGENGFNIIKGTRKRLSEEEERLKKSSHNFTNSNSAKAFFDEKFQNPDMLANLDNKRRKIIETKKSTALSRELGKIMRRRESSGLEDKSVGERQKMKRTTESALQTGLIQRLGFDPTHGKISQVLKSSVSGSEPKNNLLGKKKTVINDLLHYKKEKVILAPSKNEWFKKRSHREEVWQKHFGSKETKETSDGSASDLEII
SIO_010081: YIL150C
subclass of: SO_0000673
so part of: YIL150C
location: complement(61013..62728)
location: region:61013-62728:-1
so has part: feature:61013-62728:-1:exon

NP_012116.1
type: Protein
SIO_000068: ncbiprotein

S000001412
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:61013-62728:-1:exon

YIL149C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MLP2
locus tag: YIL149C
so part of: sequence
location: complement(<63028..>68067)
location: region:63028-68067:-1
so has part: feature:63028-68067:-1:exon
subclass of: SO_0000010

854657
type: Gene
SIO_000068: ncbigene

position:63028:-1
position: 63028
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:68067:-1
position: 68067
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:63028-68067:-1:exon

YIL149C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MLP2
locus tag: YIL149C
product: Mlp2p
transcript id: NM_001179497.3
SIO_010081: YIL149C
subclass of: SO_0000673
so part of: YIL149C
location: complement(<63028..>68067)
location: region:63028-68067:-1
so has part: feature:63028-68067:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:63028-68067:-1:exon

YIL149C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MLP2
locus tag: YIL149C
experiment: EXISTENCE:direct assay:GO:0005635 nuclear envelope [PMID:10085285]
experiment: EXISTENCE:direct assay:GO:0005654 nucleoplasm [PMID:10085285]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005816 spindle pole body [PMID:16027220]
experiment: EXISTENCE:direct assay:GO:0044615 nuclear pore nuclear basket [PMID:24152732]
experiment: EXISTENCE:genetic interaction:GO:0006355 regulation of DNA-templated transcription [PMID:15692572]
experiment: EXISTENCE:genetic interaction:GO:0006606 protein import into nucleus [PMID:10085285]
experiment: EXISTENCE:genetic interaction:GO:0034398 telomere tethering at nuclear periphery [PMID:10638763]
experiment: EXISTENCE:genetic interaction:GO:0043021 ribonucleoprotein complex binding [PMID:15692572]
experiment: EXISTENCE:genetic interaction:GO:1901925 negative regulation of protein import into nucleus during spindle assembly checkpoint [PMID:23177738]
experiment: EXISTENCE:mutant phenotype:GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery [PMID:20932479]
experiment: EXISTENCE:mutant phenotype:GO:0000973 post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery [PMID:20932479]
experiment: EXISTENCE:mutant phenotype:GO:0016973 poly(A)+ mRNA export from nucleus [PMID:21036941]
experiment: EXISTENCE:mutant phenotype:GO:0051300 spindle pole body organization [PMID:16027220]
experiment: EXISTENCE:physical interaction:GO:0005816 spindle pole body [PMID:16027220]
experiment: EXISTENCE:physical interaction:GO:0043021 ribonucleoprotein complex binding [PMID:15692572]
note: Myosin-like protein associated with the nuclear envelope; nuclear basket protein that connects the nuclear pore complex with the nuclear interior; involved in the Tel1p pathway that controls telomere length; MLP2 has a paralog, MLP1, that arose from the whole genome duplication
codon start: 1
product: Mlp2p
translation: MEDKISEFLNVPFESLQGVTYPVLRKLYKKIAKFERSEEEVTKLNVLVDEIKSQYYSRISKLKQLLDESSEQKNTAKEELNGLKDQLNEERSRYRREIDALKKQLHVSHEAMREVNDEKRVKEEYDIWQSRDQGNDSLNDDLNKENKLLRRKLMEMENILQRCKSNAISLQLKYDTSVQEKELMLQSKKLIEEKLSSFSKKTLTEEVTKSSHVENLEEKLYQMQSNYESVFTYNKFLLNQNKQLSQSVEEKVLEMKNLKDTASVEKAEFSKEMTLQKNMNDLLRSQLTSLEKDCSLRAIEKNDDNSCRNPEHTDVIDELIDTKLRLEKSKNECQRLQNIVMDCTKEEEATMTTSAVSPTVGKLFSDIKVLKRQLIKERNQKFQLQNQLEDFILELEHKTPELISFKERTKSLEHELKRSTELLETVSLTKRKQEREITSLRQKINGCEANIHSLVKQRLDLARQVKLLLLNTSAIQETASPLSQDELISLRKILESSNIVNENDSQAIITERLVEFSNVNELQEKNVELLNCIRILADKLENYEGKQDKTLQKVENQTIKEAKDAIIELENINAKMETRINILLRERDSYKLLASTEENKANTNSVTSMEAAREKKIRELEAELSSTKVENSAIIQNLRKELLIYKKSQCKKKTTLEDFENFKGLAKEKERMLEEAIDHLKAELEKQKSWVPSYIHVEKERASTELSQSRIKIKSLEYEISKLKKETASFIPTKESLTRDFEQCCKEKKELQMRLKESEISHNENKMDFSSKEGQYKAKIKELENNLERLRSDLQSKIQEIESIRSCKDSQLKWAQNTIDDTEMKMKSLLTELSNKETTIEKLSSEIENLDKELRKTKFQYKFLDQNSDASTLEPTLRKELEQIQVQLKDANSQIQAYEEIISSNENALIELKNELAKTKENYDAKIELEKKEKWAREEDLSRLRGELGEIRALQPKLKEGALHFVQQSEKLRNEVERIQKMIEKIEKMSTIVQLCKKKEMSQYQSTMKENKDLSELVIRLEKDAADCQAELTKTKSSLYSAQDLLDKHERKWMEEKADYERELISNIEQTESLRVENSVLIEKVDDTAANNGDKDHLKLVSLFSNLRHERNSLETKLTTCKRELAFVKQKNDSLEKTINDLQRTQTLSEKEYQCSAVIIDEFKDITKEVTQVNILKENNAILQKSLKNVTEKNREIYKQLNDRQEEISRLQRDLIQTKEQVSINSNKILVYESEMEQCKQRYQDLSQQQKDAQKKDIEKLTNEISDLKGKLSSAENANADLENKFNRLKKQAHEKLDASKKQQAALTNELNELKAIKDKLEQDLHFENAKVIDLDTKLKAHELQSEDVSRDHEKDTYRTLMEEIESLKKELQIFKTANSSSDAFEKLKVNMEKEKDRIIDERTKEFEKKLQETLNKSTSSEAEYSKDIETLKKEWLKEYEDETLRRIKEAEENLKKRIRLPSEERIQKIISKRKEELEEEFRKKLKENAGSLTFLDNKGSGEDAEEELWNSPSKGNSERPSAVAGFINQKNLKPQEQLKNVKNDVSFNDSQSMVTNKENNIVDSSAAGNKAIPTFSFGKPFFSSNTSSLQSFQNPFTASQSNINTNAPLRTLNIQPEVAVKAAINFSNVTDLTNNSTDGAKITEIGSTSKRPIESGTSSDPDTKKVKESPANDQASNE
SIO_010081: YIL149C
subclass of: SO_0000673
so part of: YIL149C
location: complement(63028..68067)
location: region:63028-68067:-1
so has part: feature:63028-68067:-1:exon

NP_012117.3
type: Protein
SIO_000068: ncbiprotein

S000001411
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:63028-68067:-1:exon

YIL148W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CEP52A
alternative label: UB11
alternative label: UBI1
gene: RPL40A
locus tag: YIL148W
gene synonym: CEP52A; UB11; UBI1
so part of: sequence
location: <68708..>69528
location: region:68708-69528:1
so has part: feature:68708-69528:1:exon
subclass of: SO_0000010

854658
type: Gene
SIO_000068: ncbigene

position:68708:1
position: 68708
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:69528:1
position: 69528
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:68708-69528:1:exon

YIL148W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CEP52A
alternative label: UB11
alternative label: UBI1
gene: RPL40A
locus tag: YIL148W
gene synonym: CEP52A; UB11; UBI1
product: ubiquitin-ribosomal 60S subunit protein L40A fusion protein
transcript id: NM_001179496.1
SIO_010081: YIL148W
subclass of: SO_0000673
so part of: YIL148W
location: join(<68708..68715,69150..>69528)
location: region:68708-69528:1
so has part: feature:68708-68715:1:exon
so has part: feature:69150-69528:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:68708-68715:1:exon

position:68715:1
position: 68715
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:69150-69528:1:exon

position:69150:1
position: 69150
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YIL148W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CEP52A
alternative label: UB11
alternative label: UBI1
gene: RPL40A
locus tag: YIL148W
gene synonym: CEP52A; UB11; UBI1
experiment: EXISTENCE:curator inference:GO:0002181 cytoplasmic translation [PMID:22096102]
experiment: EXISTENCE:curator inference:GO:0003735 structural constituent of ribosome [PMID:22096102]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0022625 cytosolic large ribosomal subunit [PMID:22096102]
experiment: EXISTENCE:direct assay:GO:0042254 ribosome biogenesis [PMID:2538753]
experiment: EXISTENCE:mutant phenotype:GO:0000027 ribosomal large subunit assembly [PMID:22995916]
experiment: EXISTENCE:mutant phenotype:GO:0000055 ribosomal large subunit export from nucleus [PMID:22995916]
experiment: EXISTENCE:mutant phenotype:GO:0016567 protein ubiquitination [PMID:8035826]
note: Ubiquitin-ribosomal 60S subunit protein L40A fusion protein; cleaved to yield ubiquitin and ribosomal protein L40A; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes; homologous to mammalian ribosomal protein L40, no bacterial homolog; RPL40A has a paralog, RPL40B, that arose from the whole genome duplication; relative distribution to the nucleus increases upon DNA replication stress
codon start: 1
product: ubiquitin-ribosomal 60S subunit protein L40A fusion protein
translation: MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGIIEPSLKALASKYNCDKSVCRKCYARLPPRATNCRKRKCGHTNQLRPKKKLK
SIO_010081: YIL148W
subclass of: SO_0000673
so part of: YIL148W
location: join(68708..68715,69150..69528)
location: region:68708-69528:1
so has part: feature:68708-68715:1:exon
so has part: feature:69150-69528:1:exon

NP_012118.1
type: Protein
SIO_000068: ncbiprotein

S000001410
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:68708-68715:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:69150-69528:1:exon

YIL147C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YPD2
gene: SLN1
locus tag: YIL147C
gene synonym: YPD2
so part of: sequence
location: complement(<69791..>73453)
location: region:69791-73453:-1
so has part: feature:69791-73453:-1:exon
subclass of: SO_0000010

854659
type: Gene
SIO_000068: ncbigene

position:69791:-1
position: 69791
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:73453:-1
position: 73453
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:69791-73453:-1:exon

YIL147C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YPD2
gene: SLN1
locus tag: YIL147C
gene synonym: YPD2
product: histidine kinase
transcript id: NM_001179495.1
SIO_010081: YIL147C
subclass of: SO_0000673
so part of: YIL147C
location: complement(<69791..>73453)
location: region:69791-73453:-1
so has part: feature:69791-73453:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:69791-73453:-1:exon

YIL147C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YPD2
gene: SLN1
locus tag: YIL147C
gene synonym: YPD2
EC number: 2.7.13.3
experiment: EXISTENCE:direct assay:GO:0004673 protein histidine kinase activity [PMID:8808622]
experiment: EXISTENCE:direct assay:GO:0005034 osmosensor activity [PMID:12821642]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:10198019|PMID:14665464]
experiment: EXISTENCE:direct assay:GO:0007234 osmosensory signaling via phosphorelay pathway [PMID:8808622]
experiment: EXISTENCE:direct assay:GO:0009927 histidine phosphotransfer kinase activity [PMID:12455952]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0006469 negative regulation of protein kinase activity [PMID:9482735]
experiment: EXISTENCE:mutant phenotype:GO:0006469 negative regulation of protein kinase activity [PMID:9482735]
experiment: EXISTENCE:mutant phenotype:GO:0009927 histidine phosphotransfer kinase activity [PMID:12455952]
note: Transmembrane histidine phosphotransfer kinase and osmosensor; regulates MAP kinase cascade; transmembrane protein with an intracellular kinase domain that signals to Ypd1p and Ssk1p, thereby forming a phosphorelay system similar to bacterial two-component regulators
codon start: 1
product: histidine kinase
translation: MRFGLPSKLELTPPFRIGIRTQLTALVSIVALGSLIILAVTTGVYFTSNYKNLRSDRLYIAAQLKSSQIDQTLNYLYYQAYYLASRDALQSSLTSYVAGNKSADNWVDSLSVIQKFLSSSNLFYVAKVYDSSFNAVLNATNNGTGDLIPEDVLDSLFPLSTDTPLPSSLETIGILTDPVLNSTDYLMSMSLPIFANPSIILTDSRVYGYITIIMSAEGLKSVFNDTTALEHSTIAIISAVYNSQGKASGYHFVFPPYGSRSDLPQKVFSIKNDTFISSAFRNGKGGSLKQTNILSTRNTALGYSPCSFNLVNWVAIVSQPESVFLSPATKLAKIITGTVIAIGVFVILLTLPLAHWAVQPIVRLQKATELITEGRGLRPSTPRTISRASSFKRGFSSGFAVPSSLLQFNTAEAGSTTSVSGHGGSGHGSGAAFSANSSMKSAINLGNEKMSPPEEENKIPNNHTDAKISMDGSLNHDLLGPHSLRHNDTDRSSNRSHILTTSANLTEARLPDYRRLFSDELSDLTETFNTMTDALDQHYALLEERVRARTKQLEAAKIEAEAANEAKTVFIANISHELRTPLNGILGMTAISMEETDVNKIRNSLKLIFRSGELLLHILTELLTFSKNVLQRTKLEKRDFCITDVALQIKSIFGKVAKDQRVRLSISLFPNLIRTMVLWGDSNRIIQIVMNLVSNALKFTPVDGTVDVRMKLLGEYDKELSEKKQYKEVYIKKGTEVTENLETTDKYDLPTLSNHRKSVDLESSATSLGSNRDTSTIQEEITKRNTVANESIYKKVNDREKASNDDVSSIVSTTTSSYDNAIFNSQFNKAPGSDDEEGGNLGRPIENPKTWVISIEVEDTGPGIDPSLQESVFHPFVQGDQTLSRQYGGTGLGLSICRQLANMMHGTMKLESKVGVGSKFTFTLPLNQTKEISFADMEFPFEDEFNPESRKNRRVKFSVAKSIKSRQSTSSVATPATNRSSLTNDVLPEVRSKGKHETKDVGNPNMGREEKNDNGGLEQLQEKNIKPSICLTGAEVNEQNSLSSKHRSRHEGLGSVNLDRPFLQSTGTATSSRNIPTVKDDDKNETSVKILVVEDNHVNQEVIKRMLNLEGIENIELACDGQEAFDKVKELTSKGENYNMIFMDVQMPKVDGLLSTKMIRRDLGYTSPIVALTAFADDSNIKECLESGMNGFLSKPIKRPKLKTILTEFCAAYQGKKNNK
SIO_010081: YIL147C
subclass of: SO_0000673
so part of: YIL147C
location: complement(69791..73453)
location: region:69791-73453:-1
so has part: feature:69791-73453:-1:exon

NP_012119.1
type: Protein
SIO_000068: ncbiprotein

S000001409
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:69791-73453:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS907; Autonomously replicating sequence
so part of: sequence
location: 73820..73991
location: region:73820-73991:1
so has part: feature:73820-73991:1:region

S000178111
type: SGD
SIO_000068: sgd

position:73820:1
position: 73820
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:73991:1
position: 73991
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:73820-73991:1:region

YIL146C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ECM37
gene: ATG32
locus tag: YIL146C
gene synonym: ECM37
so part of: sequence
location: complement(<74184..>75773)
location: region:74184-75773:-1
so has part: feature:74184-75773:-1:exon
subclass of: SO_0000010

854660
type: Gene
SIO_000068: ncbigene

position:74184:-1
position: 74184
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:75773:-1
position: 75773
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:74184-75773:-1:exon

YIL146C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ECM37
gene: ATG32
locus tag: YIL146C
gene synonym: ECM37
product: mitophagy protein ATG32
transcript id: NM_001179494.1
SIO_010081: YIL146C
subclass of: SO_0000673
so part of: YIL146C
location: complement(<74184..>75773)
location: region:74184-75773:-1
so has part: feature:74184-75773:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:74184-75773:-1:exon

YIL146C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ECM37
gene: ATG32
locus tag: YIL146C
gene synonym: ECM37
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:29673596]
experiment: EXISTENCE:direct assay:GO:0005741 mitochondrial outer membrane [PMID:19619494|PMID:19619495]
experiment: EXISTENCE:genetic interaction:GO:0031930 mitochondria-nucleus signaling pathway [PMID:30298458]
experiment: EXISTENCE:mutant phenotype:GO:0000422 autophagy of mitochondrion [PMID:19619494|PMID:19619495]
note: Mitochondrial outer membrane protein required to initiate mitophagy; recruits the autophagy adaptor protein Atg11p and the ubiquitin-like protein Atg8p to the mitochondrial surface to initiate mitophagy, the selective vacuolar degradation of mitochondria in response to starvation; can promote pexophagy when placed ectopically in the peroxisomal membrane; regulates mitophagy and ethanol production during alcoholic fermentation
codon start: 1
product: mitophagy protein ATG32
translation: MVLEYQQREGKGSSSKSMPPDSSSTTIHTCSEAQTGEDKGLLDPHLSVLELLSKTGHSPSPMGQNLVTSIDISGNHNVNDSISGSWQAIQPLDLGASFIPERCSSQTTNGSILSSSDTSEEEQELLQAPAADIINIIKQGQEGANVVSPSHPFKQLQKIISLPLPGKEKTPFNEQDDDGDEDEAFEEDSVTITKSLTSSTNSFVMPKLSLTQKNPVFRLLILGRTGSSFYQSIPKEYQSLFELPKYHDSATFPQYTGIVIIFQELREMVSLLNRIVQYSQGKPVIPICQPGQVIQVKNVLKSFLRNKLVKLLFPPVVVTNKRDLKKMFQRLQDLSLEYGEDVNEEDNDDEAIHTKSRSYCRNKKAENSKKKSPKSNKKPKRKKQKFFTSWFTWGISITIGISFGCCVTYFVTAAYEHQTVKSLSLRPSILASLLSLDSSSDTINTPATASPSSTEQFLWFDKGTLQINFHSDGFIMKSLTIIKETWGKMNTFVLHALSKPLKFLENLNKSSEFSIDESNRILALGYILL
SIO_010081: YIL146C
subclass of: SO_0000673
so part of: YIL146C
location: complement(74184..75773)
location: region:74184-75773:-1
so has part: feature:74184-75773:-1:exon

NP_012120.1
type: Protein
SIO_000068: ncbiprotein

S000001408
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:74184-75773:-1:exon

YIL145C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PAN6
locus tag: YIL145C
so part of: sequence
location: complement(<76354..>77283)
location: region:76354-77283:-1
so has part: feature:76354-77283:-1:exon
subclass of: SO_0000010

854661
type: Gene
SIO_000068: ncbigene

position:76354:-1
position: 76354
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:77283:-1
position: 77283
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:76354-77283:-1:exon

YIL145C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PAN6
locus tag: YIL145C
product: pantoate--beta-alanine ligase PAN6
transcript id: NM_001179493.1
SIO_010081: YIL145C
subclass of: SO_0000673
so part of: YIL145C
location: complement(<76354..>77283)
location: region:76354-77283:-1
so has part: feature:76354-77283:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:76354-77283:-1:exon

YIL145C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PAN6
locus tag: YIL145C
EC number: 6.3.2.1
experiment: EXISTENCE:direct assay:GO:0004592 pantoate-beta-alanine ligase activity [PMID:10417331]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0015940 pantothenate biosynthetic process [PMID:11154694]
note: Pantothenate synthase; also known as pantoate-beta-alanine ligase, required for pantothenic acid biosynthesis, deletion causes pantothenic acid auxotrophy, homologous to E. coli panC
codon start: 1
product: pantoate--beta-alanine ligase PAN6
translation: MKIFHTVEEVVQWRTQELRETRFRETIGFVPTMGCLHSGHASLISQSVKENTYTVVSIFVNPSQFAPTEDLDNYPRTLPDDIKLLESLKVDVLFAPNAHVMYPQGIPLDIEEQKGPFVSVLGLSEKLEGKTRPNFFRGVATVVTKLFNIVMADVAYFGQKDIQQFIVLQCMVDELFVNTRLQMMPIVRNNNGLALSSRNKYLCPESLKISENLYRGLKAAENAIRRLAPGGRLSRSEIIDTVTQIWAPYVDSHDFKIDYVSLADFKTLDELSDVENTSEQQPIVISCAVYVTDREKPDTVVRLIDNIVI
SIO_010081: YIL145C
subclass of: SO_0000673
so part of: YIL145C
location: complement(76354..77283)
location: region:76354-77283:-1
so has part: feature:76354-77283:-1:exon

NP_012121.2
type: Protein
SIO_000068: ncbiprotein

S000001407
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:76354-77283:-1:exon

YIL144W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: HEC1
alternative label: TID3
gene: NDC80
locus tag: YIL144W
gene synonym: HEC1; TID3
so part of: sequence
location: <78074..>80149
location: region:78074-80149:1
so has part: feature:78074-80149:1:exon
subclass of: SO_0000010

854662
type: Gene
SIO_000068: ncbigene

position:78074:1
position: 78074
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:80149:1
position: 80149
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:78074-80149:1:exon

YIL144W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: HEC1
alternative label: TID3
gene: NDC80
locus tag: YIL144W
gene synonym: HEC1; TID3
product: kinetochore-associated Ndc80 complex subunit NDC80
transcript id: NM_001179492.3
SIO_010081: YIL144W
subclass of: SO_0000673
so part of: YIL144W
location: <78074..>80149
location: region:78074-80149:1
so has part: feature:78074-80149:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:78074-80149:1:exon

YIL144W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: HEC1
alternative label: TID3
gene: NDC80
locus tag: YIL144W
gene synonym: HEC1; TID3
experiment: EXISTENCE:direct assay:GO:0000776 kinetochore [PMID:11511347|PMID:27170178]
experiment: EXISTENCE:direct assay:GO:0000779 condensed chromosome, centromeric region [PMID:11266451]
experiment: EXISTENCE:direct assay:GO:0008017 microtubule binding [PMID:17195848]
experiment: EXISTENCE:direct assay:GO:0031262 Ndc80 complex [PMID:11266451|PMID:11179222]
experiment: EXISTENCE:mutant phenotype:GO:0000776 kinetochore [PMID:11179222]
experiment: EXISTENCE:mutant phenotype:GO:0007059 chromosome segregation [PMID:11266451]
experiment: EXISTENCE:mutant phenotype:GO:0034501 protein localization to kinetochore [PMID:19893618|PMID:19952112]
experiment: EXISTENCE:physical interaction:GO:0031262 Ndc80 complex [PMID:11179222]
note: Component of the kinetochore-associated Ndc80 complex; conserved coiled-coil protein involved in chromosome segregation, spindle checkpoint activity, and kinetochore assembly and clustering; evolutionarily conserved; complex members include Ndc80p, Nuf2p, Scp24p, and Spc25p; modified by sumoylation
codon start: 1
product: kinetochore-associated Ndc80 complex subunit NDC80
translation: MQSSTSTDQHVLHHMDPHRFTSQIPTATSSQLRRRNSTNQGLTDMINKSIARNTISGTGIPTGGINKNKRTRSTVAGGTNGTALALNDKSNSRNSVSRLSINQLGSLQQHLSNRDPRPLRDKNFQSAIQEEIYDYLKKNKFDIETNHPISIKFLKQPTQKGFIIIFKWLYLRLDPGYGFTKSIENEIYQILKNLRYPFLESINKSQISAVGGSNWHKFLGMLHWMVRTNIKLDMCLNKVDRSLINQNTQEITILSQPLKTLDEQDQRQERYELMVEKLLIDYFTESYKSFLKLEDNYEPSMQELKLGFEKFVHIINTDIANLQTQNDNLYEKYQEVMKISQKIKTTREKWKALKSDSNKYENYVNAMKQKSQEWPGKLEKMKSECELKEEEIKALQSNISELHKILRKKGISTEQFELQNQEREKLTRELDKINIQSDKLTSSIKSRKLEAEGIFKSLLDTLRQYDSSIQNLTRSRSQLGHNVNDSSLKINISENLLDRDFHEGISYEQLFPKGSGINESIKKSILKLNDEIQERIKTIEKDNITLEKDIKNLKHDINEKTQINEKLELELSEANSKFELSKQENERLLVAQRIEIEKMEKKINDSNLLMKTKISDAEELVTSTELKLEELKVDLNRKRYKLHQQVIHVIDITSKFKINIQSSLENSENELGNVIEELRNLEFETEHNVTN
SIO_010081: YIL144W
subclass of: SO_0000673
so part of: YIL144W
location: 78074..80149
location: region:78074-80149:1
so has part: feature:78074-80149:1:exon

NP_012122.3
type: Protein
SIO_000068: ncbiprotein

S000001406
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:78074-80149:1:exon

YIL143C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LOM3
alternative label: RAD25
gene: SSL2
locus tag: YIL143C
gene synonym: LOM3; RAD25
so part of: sequence
location: complement(<80510..>83041)
location: region:80510-83041:-1
so has part: feature:80510-83041:-1:exon
subclass of: SO_0000010

854663
type: Gene
SIO_000068: ncbigene

position:80510:-1
position: 80510
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:83041:-1
position: 83041
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:80510-83041:-1:exon

YIL143C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LOM3
alternative label: RAD25
gene: SSL2
locus tag: YIL143C
gene synonym: LOM3; RAD25
product: TFIIH/NER complex ATPase/helicase subunit SSL2
transcript id: NM_001179491.1
SIO_010081: YIL143C
subclass of: SO_0000673
so part of: YIL143C
location: complement(<80510..>83041)
location: region:80510-83041:-1
so has part: feature:80510-83041:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:80510-83041:-1:exon

YIL143C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LOM3
alternative label: RAD25
gene: SSL2
locus tag: YIL143C
gene synonym: LOM3; RAD25
EC number: 3.6.4.12
experiment: EXISTENCE:direct assay:GO:0000112 nucleotide-excision repair factor 3 complex [PMID:8855246]
experiment: EXISTENCE:direct assay:GO:0000439 transcription factor TFIIH core complex [PMID:7961739]
experiment: EXISTENCE:direct assay:GO:0003678 DNA helicase activity [PMID:8202161]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0005675 transcription factor TFIIH holo complex [PMID:19818408|PMID:27381459]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0006289 nucleotide-excision repair [PMID:8631896]
experiment: EXISTENCE:direct assay:GO:0006366 transcription by RNA polymerase II [PMID:19818408]
experiment: EXISTENCE:direct assay:GO:0032508 DNA duplex unwinding [PMID:22751016]
experiment: EXISTENCE:direct assay:GO:0070816 phosphorylation of RNA polymerase II C-terminal domain [PMID:19450536|PMID:19679665]
experiment: EXISTENCE:direct assay:GO:0097550 transcription preinitiation complex [PMID:22751016]
experiment: EXISTENCE:mutant phenotype:GO:0000019 regulation of mitotic recombination [PMID:10713167]
experiment: EXISTENCE:mutant phenotype:GO:0001111 RNA polymerase II promoter clearance [PMID:10713451]
experiment: EXISTENCE:mutant phenotype:GO:0001113 transcription open complex formation at RNA polymerase II promoter [PMID:10409754]
experiment: EXISTENCE:mutant phenotype:GO:0001174 transcriptional start site selection at RNA polymerase II promoter [PMID:34652274]
experiment: EXISTENCE:mutant phenotype:GO:0006367 transcription initiation at RNA polymerase II promoter [PMID:25775526]
experiment: EXISTENCE:mutant phenotype:GO:0010525 regulation of transposition, RNA-mediated [PMID:10713167]
experiment: EXISTENCE:mutant phenotype:GO:0015616 DNA translocase activity [PMID:25775526]
experiment: EXISTENCE:mutant phenotype:GO:0016973 poly(A)+ mRNA export from nucleus [PMID:17212653]
note: Component of RNA polymerase transcription factor TFIIH holoenzyme; acts as dsDNA-dependent translocase in context of TFIIH, unwinds DNA strands during initiation and promotes transcription start site (TSS) scanning; has DNA-dependent ATPase/helicase activity; interacts functionally with TFIIB, has roles in TSS selection and gene looping to juxtapose initiation and termination regions; involved in DNA repair; relocalizes to cytosol under hypoxia; homolog of human ERCC3
codon start: 1
product: TFIIH/NER complex ATPase/helicase subunit SSL2
translation: MTDVEGYQPKSKGKIFPDMGESFFSSDEDSPATDAEIDENYDDNRETSEGRGERDTGAMVTGLKKPRKKTKSSRHTAADSSMNQMDAKDKALLQDTNSDIPADFVPDSVSGMFRSHDFSYLRLRPDHASRPLWISPSDGRIILESFSPLAEQAQDFLVTIAEPISRPSHIHEYKITAYSLYAAVSVGLETDDIISVLDRLSKVPVAESIINFIKGATISYGKVKLVIKHNRYFVETTQADILQMLLNDSVIGPLRIDSDHQVQPPEDVLQQQLQQTAGKPATNVNPNDVEAVFSAVIGGDNEREEEDDDIDAVHSFEIANESVEVVKKRCQEIDYPVLEEYDFRNDHRNPDLDIDLKPSTQIRPYQEKSLSKMFGNGRARSGIIVLPCGAGKTLVGITAACTIKKSVIVLCTSSVSVMQWRQQFLQWCTLQPENCAVFTSDNKEMFQTESGLVVSTYSMVANTRNRSHDSQKVMDFLTGREWGFIILDEVHVVPAAMFRRVVSTIAAHAKLGLTATLVREDDKIGDLNFLIGPKLYEANWMELSQKGHIANVQCAEVWCPMTAEFYQEYLRETARKRMLLYIMNPTKFQACQFLIQYHERRGDKIIVFSDNVYALQEYALKMGKPFIYGSTPQQERMNILQNFQYNDQINTIFLSKVGDTSIDLPEATCLIQISSHYGSRRQEAQRLGRILRAKRRNDEGFNAFFYSLVSKDTQEMYYSTKRQAFLVDQGYAFKVITHLHGMENIPNLAYASPRERRELLQEVLLKNEEAAGIEVGDDADNSVGRGSNGHKRFKSKAVRGEGSLSGLAGGEDMAYMEYSTNKNKELKEHHPLIRKMYYKNLKK
SIO_010081: YIL143C
subclass of: SO_0000673
so part of: YIL143C
location: complement(80510..83041)
location: region:80510-83041:-1
so has part: feature:80510-83041:-1:exon

NP_012123.1
type: Protein
SIO_000068: ncbiprotein

S000001405
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:80510-83041:-1:exon

YIL142W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: BIN3
alternative label: TCP2
gene: CCT2
locus tag: YIL142W
gene synonym: BIN3; TCP2
so part of: sequence
location: <83302..>84885
location: region:83302-84885:1
so has part: feature:83302-84885:1:exon
subclass of: SO_0000010

854664
type: Gene
SIO_000068: ncbigene

position:83302:1
position: 83302
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:84885:1
position: 84885
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:83302-84885:1:exon

YIL142W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: BIN3
alternative label: TCP2
gene: CCT2
locus tag: YIL142W
gene synonym: BIN3; TCP2
product: chaperonin-containing T-complex subunit CCT2
transcript id: NM_001179490.1
SIO_010081: YIL142W
subclass of: SO_0000673
so part of: YIL142W
location: <83302..>84885
location: region:83302-84885:1
so has part: feature:83302-84885:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:83302-84885:1:exon

YIL142W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: BIN3
alternative label: TCP2
gene: CCT2
locus tag: YIL142W
gene synonym: BIN3; TCP2
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005832 chaperonin-containing T-complex [PMID:16762366]
experiment: EXISTENCE:direct assay:GO:0006457 protein folding [PMID:16762366]
experiment: EXISTENCE:direct assay:GO:0051082 unfolded protein binding [PMID:16762366]
experiment: EXISTENCE:physical interaction:GO:0005832 chaperonin-containing T-complex [PMID:15704212]
note: Subunit beta of the cytosolic chaperonin Cct ring complex; related to Tcp1p, required for the assembly of actin and tubulins in vivo
codon start: 1
product: chaperonin-containing T-complex subunit CCT2
translation: MSVQIFGDQVTEERAENARLSAFVGAIAVGDLVKSTLGPKGMDKLLQSASSNTCMVTNDGATILKSIPLDNPAAKVLVNISKVQDDEVGDGTTSVTVLSAELLREAEKLIDQSKIHPQTIIEGYRLASAAALDALTKAAVDNSHDKTMFREDLIHIAKTTLSSKILSQDKDHFAELATNAILRLKGSTNLEHIQIIKILGGKLSDSFLDEGFILAKKFGNNQPKRIENAKILIANTTLDTDKVKIFGTKFKVDSTAKLAQLEKAEREKMKNKIAKISKFGINTFINRQLIYDYPEQLFTDLGINSIEHADFEGVERLALVTGGEVVSTFDEPSKCKLGECDVIEEIMLGEQPFLKFSGCKAGEACTIVLRGATDQTLDEAERSLHDALSVLSQTTKETRTVLGGGCAEMVMSKAVDTEAQNIDGKKSLAVEAFARALRQLPTILADNAGFDSSELVSKLRSSIYNGISTSGLDLNNGTIADMRQLGIVESYKLKRAVVSSASEAAEVLLRVDNIIRARPRTANRQHM
SIO_010081: YIL142W
subclass of: SO_0000673
so part of: YIL142W
location: 83302..84885
location: region:83302-84885:1
so has part: feature:83302-84885:1:exon

NP_012124.1
type: Protein
SIO_000068: ncbiprotein

S000001404
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:83302-84885:1:exon

YIL140W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: BUD10
alternative label: SRO4
gene: AXL2
locus tag: YIL140W
gene synonym: BUD10; SRO4
so part of: sequence
location: <85366..>87837
location: region:85366-87837:1
so has part: feature:85366-87837:1:exon
subclass of: SO_0000010

854666
type: Gene
SIO_000068: ncbigene

position:85366:1
position: 85366
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:87837:1
position: 87837
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:85366-87837:1:exon

YIL140W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: BUD10
alternative label: SRO4
gene: AXL2
locus tag: YIL140W
gene synonym: BUD10; SRO4
product: Axl2p
transcript id: NM_001179488.1
SIO_010081: YIL140W
subclass of: SO_0000673
so part of: YIL140W
location: <85366..>87837
location: region:85366-87837:1
so has part: feature:85366-87837:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:85366-87837:1:exon

YIL140W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: BUD10
alternative label: SRO4
gene: AXL2
locus tag: YIL140W
gene synonym: BUD10; SRO4
experiment: EXISTENCE:direct assay:GO:0000131 incipient cellular bud site [PMID:8846915]
experiment: EXISTENCE:direct assay:GO:0000144 cellular bud neck septin ring [PMID:8846915]
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:8846915]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:15282802]
experiment: EXISTENCE:direct assay:GO:0032153 cell division site [PMID:8846915]
experiment: EXISTENCE:mutant phenotype:GO:0007120 axial cellular bud site selection [PMID:8846915]
note: Integral plasma membrane protein; required for axial budding in haploid cells; localizes to the incipient bud site and bud neck; glycosylated by Pmt4p; potential Cdc28p substrate
codon start: 1
product: Axl2p
translation: MTQLQISLLLTATISLLHLVVATPYEAYPIGKQYPPVARVNESFTFQISNDTYKSSVDKTAQITYNCFDLPSWLSFDSSSRTFSGEPSSDLLSDANTTLYFNVILEGTDSADSTSLNNTYQFVVTNRPSISLSSDFNLLALLKNYGYTNGKNALKLDPNEVFNVTFDRSMFTNEESIVSYYGRSQLYNAPLPNWLFFDSGELKFTGTAPVINSAIAPETSYSFVIIATDIEGFSAVEVEFELVIGAHQLTTSIQNSLIINVTDTGNVSYDLPLNYVYLDDDPISSDKLGSINLLDAPDWVALDNATISGSVPDELLGKNSNPANFSVSIYDTYGDVIYFNFEVVSTTDLFAISSLPNINATRGEWFSYYFLPSQFTDYVNTNVSLEFTNSSQDHDWVKFQSSNLTLAGEVPKNFDKLSLGLKANQGSQSQELYFNIIGMDSKITHSNHSANATSTRSSHHSTSTSSYTSSTYTAKISSTSAAATSSAPAALPAANKTSSHNKKAVAIACGVAIPLGVILVALICFLIFWRRRRENPDDENLPHAISGPDLNNPANKPNQENATPLNNPFDDDASSYDDTSIARRLAALNTLKLDNHSATESDISSVDEKRDSLSGMNTYNDQFQSQSKEELLAKPPVQPPESPFFDPQNRSSSVYMDSEPAVNKSWRYTGNLSPVSDIVRDSYGSQKTVDTEKLFDLEAPEKEKRTSRDVTMSSLDPWNSNISPSPVRKSVTPSPYNVTKHRNRHLQNIQDSQSGKNGITPTTMSTSSSDDFVPVKDGENFCWVHSMEPDRRPSKKRLVDFSNKSNVNVGQVKDIHGRIPEML
SIO_010081: YIL140W
subclass of: SO_0000673
so part of: YIL140W
location: 85366..87837
location: region:85366-87837:1
so has part: feature:85366-87837:1:exon

NP_012126.1
type: Protein
SIO_000068: ncbiprotein

S000001402
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:85366-87837:1:exon

YIL139C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: REV7
locus tag: YIL139C
so part of: sequence
location: complement(<87979..>88716)
location: region:87979-88716:-1
so has part: feature:87979-88716:-1:exon
subclass of: SO_0000010

854667
type: Gene
SIO_000068: ncbigene

position:87979:-1
position: 87979
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:88716:-1
position: 88716
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:87979-88716:-1:exon

YIL139C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: REV7
locus tag: YIL139C
product: Rev7p
transcript id: NM_001179487.1
SIO_010081: YIL139C
subclass of: SO_0000673
so part of: YIL139C
location: complement(<87979..>88716)
location: region:87979-88716:-1
so has part: feature:87979-88716:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:87979-88716:-1:exon

YIL139C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: REV7
locus tag: YIL139C
experiment: EXISTENCE:direct assay:GO:0000785 chromatin [PMID:16546083]
experiment: EXISTENCE:direct assay:GO:0003887 DNA-directed DNA polymerase activity [PMID:8658138]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16452144]
experiment: EXISTENCE:direct assay:GO:0016035 zeta DNA polymerase complex [PMID:8658138|PMID:23066099|PMID:22711820]
experiment: EXISTENCE:direct assay:GO:0042276 error-prone translesion synthesis [PMID:11313481]
experiment: EXISTENCE:direct assay:GO:0070987 error-free translesion synthesis [PMID:12514101]
experiment: EXISTENCE:genetic interaction:GO:0042276 error-prone translesion synthesis [PMID:9765213]
experiment: EXISTENCE:mutant phenotype:GO:0042276 error-prone translesion synthesis [PMID:3897795]
note: Accessory subunit of DNA polymerase zeta; involved in translesion synthesis during post-replication repair; required for mutagenesis induced by DNA damage; involved in double-strand break repair; may be involved in meiosis; forms a complex with Rev3p, Pol31p and Pol32p
codon start: 1
product: Rev7p
translation: MNRWVEKWLRVYLKCYINLILFYRNVYPPQSFDYTTYQSFNLPQFVPINRHPALIDYIEELILDVLSKLTHVYRFSICIINKKNDLCIEKYVLDFSELQHVDKDDQIITETEVFDEFRSSLNSLIMHLEKLPKVNDDTITFEAVINAIELELGHKLDRNRRVDSLEEKAEIERDSNWVKCQEDENLPDNNGFQPPKIKLTSLVGSDVGPLIIHQFSEKLISGDDKILNGVYSQYEEGESIFGSLF
SIO_010081: YIL139C
subclass of: SO_0000673
so part of: YIL139C
location: complement(87979..88716)
location: region:87979-88716:-1
so has part: feature:87979-88716:-1:exon

NP_012127.1
type: Protein
SIO_000068: ncbiprotein

S000001401
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:87979-88716:-1:exon

YIL138C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TPM2
locus tag: YIL138C
so part of: sequence
location: complement(<89230..>89715)
location: region:89230-89715:-1
so has part: feature:89230-89715:-1:exon
subclass of: SO_0000010

854668
type: Gene
SIO_000068: ncbigene

position:89230:-1
position: 89230
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:89715:-1
position: 89715
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:89230-89715:-1:exon

YIL138C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TPM2
locus tag: YIL138C
product: tropomyosin TPM2
transcript id: NM_001179486.3
SIO_010081: YIL138C
subclass of: SO_0000673
so part of: YIL138C
location: complement(<89230..>89715)
location: region:89230-89715:-1
so has part: feature:89230-89715:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:89230-89715:-1:exon

YIL138C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TPM2
locus tag: YIL138C
experiment: EXISTENCE:direct assay:GO:0000142 cellular bud neck contractile ring [PMID:9864365]
experiment: EXISTENCE:direct assay:GO:0003786 actin lateral binding [PMID:11457840]
experiment: EXISTENCE:direct assay:GO:0005884 actin filament [PMID:7844152]
experiment: EXISTENCE:direct assay:GO:0032432 actin filament bundle [PMID:9864365]
experiment: EXISTENCE:direct assay:GO:1904530 negative regulation of actin filament binding [PMID:7844152]
experiment: EXISTENCE:genetic interaction:GO:0051017 actin filament bundle assembly [PMID:9864365]
experiment: EXISTENCE:genetic interaction:GO:1903475 mitotic actomyosin contractile ring assembly [PMID:12419188]
experiment: EXISTENCE:mutant phenotype:GO:0000282 cellular bud site selection [PMID:7844152]
note: Minor isoform of tropomyosin; binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; appears to have distinct and also overlapping functions with Tpm1p; TPM2 has a paralog, TPM1, that arose from the whole genome duplication
codon start: 1
product: tropomyosin TPM2
translation: MEKIKEKLNSLKLESESWQEKYEELREQLKELEQSNTEKENEIKSLSAKNEQLDSEVEKLESQLSDTKQLAEDSNNLRSNNENYTKKNQDLEQQLEDSEAKLKEAMDKLKEADLNSEQMGRRIVALEEERDEWEKKCEEFQSKYEEAQKELDEIANSLENL
SIO_010081: YIL138C
subclass of: SO_0000673
so part of: YIL138C
location: complement(89230..89715)
location: region:89230-89715:-1
so has part: feature:89230-89715:-1:exon

NP_012128.3
type: Protein
SIO_000068: ncbiprotein

S000001400
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:89230-89715:-1:exon

YIL137C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: TAE3
gene: TMA108
locus tag: YIL137C
gene synonym: TAE3
so part of: sequence
location: complement(<89948..>92788)
location: region:89948-92788:-1
so has part: feature:89948-92788:-1:exon
subclass of: SO_0000010

854669
type: Gene
SIO_000068: ncbigene

position:89948:-1
position: 89948
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:92788:-1
position: 92788
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:89948-92788:-1:exon

YIL137C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: TAE3
gene: TMA108
locus tag: YIL137C
gene synonym: TAE3
product: Tma108p
transcript id: NM_001179485.1
SIO_010081: YIL137C
subclass of: SO_0000673
so part of: YIL137C
location: complement(<89948..>92788)
location: region:89948-92788:-1
so has part: feature:89948-92788:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:89948-92788:-1:exon

YIL137C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: TAE3
gene: TMA108
locus tag: YIL137C
gene synonym: TAE3
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005854 nascent polypeptide-associated complex [PMID:27580715]
experiment: EXISTENCE:direct assay:GO:1990593 nascent polypeptide-associated complex binding [PMID:27580715]
experiment: EXISTENCE:genetic interaction:GO:0042254 ribosome biogenesis [PMID:20691087]
experiment: EXISTENCE:mutant phenotype:GO:0042254 ribosome biogenesis [PMID:20691087]
experiment: EXISTENCE:mutant phenotype:GO:2000765 regulation of cytoplasmic translation [PMID:27580715]
note: Ribosome-associated, nascent chain binding factor; binds N-terminal region of nascent peptides during translation; recognizes target proteins via its putative metallopeptidase peptide-binding pocket
codon start: 1
product: Tma108p
translation: MSDNLLSLENPVVPSHYELRLEIDPKQSSPNFKGSAIIHLKFNPNSTTLASIEDSFTQFKLHSKDLIVLSAHATIGSTKFDLKISQDTGKHLSIFNSESPIQLSNDCPLILSVQYVGKIRDIKTHHDKTFGIFKTNFMDRKTGTANNHVVATHCQPFSASNIFPCIDEPSNKSTFQLNIATDAQYKAVSNTPVEMVEALDSSQKHLVKFAKTPLMTTSVFGFSIGDLEFLKTEIKLEGDRTIPVSIYAPWDIANAAFTLDTVQKYLPLLESYFKCPYPLPKLDFVLLPYLSDMAMENFGMITIQLNHLLIPPNALANETVREQAQQLIVHELVHQWMGNYISFDSWESLWFNESFATWLACHILEQNGDLSHYWTSEPYLLQQVEPTMCRDAADVNGRSIFQIAQRNTGIDSQTSDIFDPEAYTKGIIMLRSLQLATGESHLQKGLESVFEDTKTFHARSVKPMDIWNHIGKFLKSQNITNFVSSWTRTPGLPVVKVEVEEKDGKTQTKLTQHRFINQLSTEEKDQLEDVPYQVPLFGVLPDGKMDTKNVLLTDRTLKFDYPILVINHLAQGYYRVSYESEECYALINDKITEETLSEIDLRKIFLDLSQFIGDEGFQNSIHLHGLFKILNHIASPSTKIASKYWDPLSKGLEVLQTIDRASLTSSKLQSFLKKKIVIPLFNKIDWPHGEFDKSTNPHELKVMSQVLFLNKNSAKCAELCQIYFKHLLQGPRSSVPLELVNSILVVVSQHCANIKQWKKIFDLVKRSSCTGITNHVINMYDQNSSETAMLIQNGAIESLGFCLDSDIVKKTLNFITSNIESEGMELALFGFNYNFKKRLNKNEKPQDQVVRETIWEWYMGNFDQWARKATRKGTTTGDHLHKALRSISLIIFQMFVADEPQKIEKFINLEKEKLGQSLLSLDDIWASVQQDEESRKTIRRDLASLV
SIO_010081: YIL137C
subclass of: SO_0000673
so part of: YIL137C
location: complement(89948..92788)
location: region:89948-92788:-1
so has part: feature:89948-92788:-1:exon

NP_012129.1
type: Protein
SIO_000068: ncbiprotein

S000001399
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:89948-92788:-1:exon

YIL136W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: OM45
locus tag: YIL136W
so part of: sequence
location: <93619..>94800
location: region:93619-94800:1
so has part: feature:93619-94800:1:exon
subclass of: SO_0000010

854670
type: Gene
SIO_000068: ncbigene

position:93619:1
position: 93619
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:94800:1
position: 94800
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:93619-94800:1:exon

YIL136W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: OM45
locus tag: YIL136W
product: Om45p
transcript id: NM_001179484.1
SIO_010081: YIL136W
subclass of: SO_0000673
so part of: YIL136W
location: <93619..>94800
location: region:93619-94800:1
so has part: feature:93619-94800:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:93619-94800:1:exon

YIL136W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: OM45
locus tag: YIL136W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:11502169|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005741 mitochondrial outer membrane [PMID:16689936|PMID:11179417|PMID:16407407]
note: Mitochondrial outer membrane hypothetical protein; major constituent of the outer membrane, extending into the intermembrane space; interacts with porin (Por1p) and with Om14p; imported via the presequence pathway involving the TOM and TIM23 complexes, then assembled in the outer membrane by Mim1p; protein abundance increases in response to DNA replication stress
codon start: 1
product: Om45p
translation: MSSRIIVGSAALAAAITASIMVREQKAKGQRREGNVSAYYNGQEYGSSAPPQLGKLHNIKQGIKEDALSLKDALLGVSQKAREEAPKVTKRVISPEEDAQTRKQLGQKAKDSSSQSIFNWGFSEAERRKAIAIGEFDTAKKRFEEAVDRNEKELLSTVMREKKAALDRASIEYERYGRARDFNELSDKLDQQERNSNPLKRLLKNNTGDANTEEAAARSVQGWGDTAQEFGREELEEAKRNASSEPSEAQKRLDELKKIKEKGWFGYNKGEQSEQQIAERVARGLEGWGETAAQLSKDEMDDLRWNYENSKKQLDKNVSDAMDSLSKAKEDLKQYGSHWWSGWTSKVDNDKQALKDEAQKKYDEALKKYDEAKNKFKEWNDKGDGKFWSSKKD
SIO_010081: YIL136W
subclass of: SO_0000673
so part of: YIL136W
location: 93619..94800
location: region:93619-94800:1
so has part: feature:93619-94800:1:exon

NP_012130.1
type: Protein
SIO_000068: ncbiprotein

S000001398
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:93619-94800:1:exon

YIL135C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: VHS2
locus tag: YIL135C
so part of: sequence
location: complement(<95065..>96375)
location: region:95065-96375:-1
so has part: feature:95065-96375:-1:exon
subclass of: SO_0000010

854671
type: Gene
SIO_000068: ncbigene

position:95065:-1
position: 95065
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:96375:-1
position: 96375
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:95065-96375:-1:exon

YIL135C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: VHS2
locus tag: YIL135C
product: Vhs2p
transcript id: NM_001179483.1
SIO_010081: YIL135C
subclass of: SO_0000673
so part of: YIL135C
location: complement(<95065..>96375)
location: region:95065-96375:-1
so has part: feature:95065-96375:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:95065-96375:-1:exon

YIL135C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: VHS2
locus tag: YIL135C
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:16816427|PMID:14562095]
experiment: EXISTENCE:genetic interaction:GO:0030950 establishment or maintenance of actin cytoskeleton polarity [PMID:16816427]
experiment: EXISTENCE:genetic interaction:GO:0032186 cellular bud neck septin ring organization [PMID:24646733]
experiment: EXISTENCE:mutant phenotype:GO:0032186 cellular bud neck septin ring organization [PMID:24646733]
note: Regulator of septin dynamics; involved in the regulation of septin dynamics at bud neck after mitotic entry, likely by stabilizing septin structure; regulated at post-translational level by cell cycle dependent phosphorylation; likely phosphorylated by Cdc28p and dephosphorylated by Cdc14p before cytokinesis; high-copy suppressor of synthetic lethality of sis2 sit4 double mutant; VHS2 has a paralog, MLF3, that arose from the whole genome duplication
codon start: 1
product: Vhs2p
translation: MDTSNHNQDHDSHVAAQRENDNNYMPPSPSMSESSMIFERNVEDPSYLYKTVSNNAANSLSRQSSRTSLFNHNNSSNRNFHNLSQRSSAVNLHLQPSRTNESIASYQTYNPDFVVQTPLDHRRTLENFVPPALDAGCSIVTDDTTGLDDVDMVYSRRPSTIGLDRALGRTRSLSSQSFDNETSPAHPRSPNDHGSRLLRFYSYADMLSDDNNNNVSNATSTSSTANPLRRPPMQGHYSFSSSLLNSPSHLPSPPSASASPPQHMNFTNPFIISRRYSNTTINNANGGTSAGSTTGAALSRSPSNQQYLLKQQRSPSGSARSRRNSNRPGSAANIMIGKPKSKFHMESSGSEGFSSEEEDNTMIERDKLNLKQKLQSQLAQPPSIANMVNDNHNNTNKHKNTINNNIKNSPAFTNSNPSSKSNSNSTITSMNPDTTK
SIO_010081: YIL135C
subclass of: SO_0000673
so part of: YIL135C
location: complement(95065..96375)
location: region:95065-96375:-1
so has part: feature:95065-96375:-1:exon

NP_012131.1
type: Protein
SIO_000068: ncbiprotein

S000001397
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:95065-96375:-1:exon

YIL134C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YIL134C-A
so part of: sequence
location: complement(<96522..>96725)
location: region:96522-96725:-1
so has part: feature:96522-96725:-1:exon
subclass of: SO_0000010

1466491
type: Gene
SIO_000068: ncbigene

position:96522:-1
position: 96522
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:96725:-1
position: 96725
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:96522-96725:-1:exon

YIL134C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YIL134C-A
product: uncharacterized protein
transcript id: NM_001184555.1
SIO_010081: YIL134C-A
subclass of: SO_0000673
so part of: YIL134C-A
location: complement(<96522..>96725)
location: region:96522-96725:-1
so has part: feature:96522-96725:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:96522-96725:-1:exon

YIL134C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YIL134C-A
note: hypothetical protein; identified by fungal homology and RT-PCR
codon start: 1
product: uncharacterized protein
translation: MVVGSEFNNTADVDVVAILLTLLNADYFVIKQRLVSACFTKRIKWYFIYAIALLSLFSSRNTVCAPY
SIO_010081: YIL134C-A
subclass of: SO_0000673
so part of: YIL134C-A
location: complement(96522..96725)
location: region:96522-96725:-1
so has part: feature:96522-96725:-1:exon

NP_878096.1
type: Protein
SIO_000068: ncbiprotein

S000028556
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:96522-96725:-1:exon

YNCI0001W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SNR68
locus tag: YNCI0001W
so part of: sequence
location: 97111..97246
location: region:97111-97246:1
so has part: feature:97111-97246:1:exon
subclass of: SO_0000578

9164907
type: Gene
SIO_000068: ncbigene

position:97111:1
position: 97111
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:97246:1
position: 97246
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:97111-97246:1:exon

YNCI0001W
type: Non Coding RNA
subclass of: SO_0000655
RO_0002162: 559292
nc RNA class: snoRNA
gene: SNR68
locus tag: YNCI0001W
product: SNR68
experiment: EXISTENCE:curator inference:GO:0005730 nucleolus [PMID:10024243]
experiment: EXISTENCE:curator inference:GO:0031428 box C/D RNP complex [PMID:10024243]
experiment: EXISTENCE:mutant phenotype:GO:0030562 rRNA 2'-O-ribose methylation guide activity [PMID:10024243]
experiment: EXISTENCE:mutant phenotype:GO:0031167 rRNA methylation [PMID:10024243]
note: C/D box small nucleolar RNA (snoRNA); guides 2'-O-methylation of large subunit (LSU) rRNA at position A2640
transcript id: NR_132190.1
SIO_010081: YNCI0001W
subclass of: SO_0000673
so part of: YNCI0001W
location: 97111..97246
location: region:97111-97246:1
so has part: feature:97111-97246:1:exon

S000006459
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:97111-97246:1:exon

YIL134W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FLX1
locus tag: YIL134W
so part of: sequence
location: <97395..>98330
location: region:97395-98330:1
so has part: feature:97395-98330:1:exon
subclass of: SO_0000010

854672
type: Gene
SIO_000068: ncbigene

position:97395:1
position: 97395
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:98330:1
position: 98330
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:97395-98330:1:exon

YIL134W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FLX1
locus tag: YIL134W
product: flavin adenine dinucleotide transporter FLX1
transcript id: NM_001179482.3
SIO_010081: YIL134W
subclass of: SO_0000673
so part of: YIL134W
location: <97395..>98330
location: region:97395-98330:1
so has part: feature:97395-98330:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:97395-98330:1:exon

YIL134W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FLX1
locus tag: YIL134W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:8631763|PMID:14576278|PMID:16823961|PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0015230 FAD transmembrane transporter activity [PMID:14555654|PMID:8631763]
experiment: EXISTENCE:mutant phenotype:GO:0015883 FAD transport [PMID:14555654]
note: Mitochondrial flavin adenine dinucleotide transporter; FAD is a synthesis product of riboflavin; human homolog SLC25A32 is implicated in multiple acyl-CoA dehydrogenase deficiency (MADD) or glutaric aciduria type II (GAII), and can complement yeast null mutant
codon start: 1
product: flavin adenine dinucleotide transporter FLX1
translation: MVDHQWTPLQKEVISGLSAGSVTTLVVHPLDLLKVRLQLSATSAQKAHYGPFMVIKEIIRSSANSGRSVTNELYRGLSINLFGNAIAWGVYFGLYGVTKELIYKSVAKPGETQLKGVGNDHKMNSLIYLSAGASSGLMTAILTNPIWVIKTRIMSTSKGAQGAYTSMYNGVQQLLRTDGFQGLWKGLVPALFGVSQGALYFAVYDTLKQRKLRRKRENGLDIHLTNLETIEITSLGKMVSVTLVYPFQLLKSNLQSFRANEQKFRLFPLIKLIIANDGFVGLYKGLSANLVRAIPSTCITFCVYENLKHRL
SIO_010081: YIL134W
subclass of: SO_0000673
so part of: YIL134W
location: 97395..98330
location: region:97395-98330:1
so has part: feature:97395-98330:1:exon

NP_012132.3
type: Protein
SIO_000068: ncbiprotein

S000001396
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:97395-98330:1:exon

YIL133C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RPL13
gene: RPL16A
locus tag: YIL133C
gene synonym: RPL13
so part of: sequence
location: complement(<98527..>99416)
location: region:98527-99416:-1
so has part: feature:98527-99416:-1:exon
subclass of: SO_0000010

854673
type: Gene
SIO_000068: ncbigene

position:98527:-1
position: 98527
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:99416:-1
position: 99416
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:98527-99416:-1:exon

YIL133C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RPL13
gene: RPL16A
locus tag: YIL133C
gene synonym: RPL13
product: ribosomal 60S subunit protein L16A
transcript id: NM_001179481.1
SIO_010081: YIL133C
subclass of: SO_0000673
so part of: YIL133C
location: complement(join(<98527..99095,99386..>99416))
location: region:98527-99416:-1
so has part: feature:99386-99416:-1:exon
so has part: feature:98527-99095:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:99386-99416:-1:exon

position:99386:-1
position: 99386
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:98527-99095:-1:exon

position:99095:-1
position: 99095
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YIL133C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RPL13
gene: RPL16A
locus tag: YIL133C
gene synonym: RPL13
experiment: EXISTENCE:curator inference:GO:0002181 cytoplasmic translation [PMID:11983894]
experiment: EXISTENCE:curator inference:GO:0003735 structural constituent of ribosome [PMID:11983894]
experiment: EXISTENCE:direct assay:GO:0003723 RNA binding [PMID:6337137]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:27374275]
experiment: EXISTENCE:direct assay:GO:0022625 cytosolic large ribosomal subunit [PMID:11983894]
experiment: EXISTENCE:mutant phenotype:GO:0000470 maturation of LSU-rRNA [PMID:27374275]
note: Ribosomal 60S subunit protein L16A; N-terminally acetylated, binds 5.8 S rRNA; transcriptionally regulated by Rap1p; homologous to mammalian ribosomal protein L13A and bacterial L13; RPL16A has a paralog, RPL16B, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress
codon start: 1
product: ribosomal 60S subunit protein L16A
translation: MSVEPVVVIDGKGHLVGRLASVVAKQLLNGQKIVVVRAEELNISGEFFRNKLKYHDFLRKATAFNKTRGPFHFRAPSRIFYKALRGMVSHKTARGKAALERLKVFEGIPPPYDKKKRVVVPQALRVLRLKPGRKYTTLGKLSTSVGWKYEDVVAKLEAKRKVSSAEYYAKKRAFTKKVASANATAAESDVAKQLAALGY
SIO_010081: YIL133C
subclass of: SO_0000673
so part of: YIL133C
location: complement(join(98527..99095,99386..99416))
location: region:98527-99416:-1
so has part: feature:99386-99416:-1:exon
so has part: feature:98527-99095:-1:exon

NP_012133.1
type: Protein
SIO_000068: ncbiprotein

S000001395
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:99386-99416:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:98527-99095:-1:exon

YIL132C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CSM2
locus tag: YIL132C
so part of: sequence
location: complement(<99860..>100501)
location: region:99860-100501:-1
so has part: feature:99860-100501:-1:exon
subclass of: SO_0000010

854674
type: Gene
SIO_000068: ncbigene

position:99860:-1
position: 99860
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:100501:-1
position: 100501
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:99860-100501:-1:exon

YIL132C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CSM2
locus tag: YIL132C
product: Csm2p
transcript id: NM_001179480.1
SIO_010081: YIL132C
subclass of: SO_0000673
so part of: YIL132C
location: complement(<99860..>100501)
location: region:99860-100501:-1
so has part: feature:99860-100501:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:99860-100501:-1:exon

YIL132C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CSM2
locus tag: YIL132C
experiment: EXISTENCE:curator inference:GO:0070987 error-free translesion synthesis [PMID:19496932]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0097196 Shu complex [PMID:23575680]
experiment: EXISTENCE:genetic interaction:GO:0000725 recombinational repair [PMID:15654096]
experiment: EXISTENCE:genetic interaction:GO:0043007 maintenance of rDNA [PMID:21372173]
experiment: EXISTENCE:mutant phenotype:GO:0000725 recombinational repair [PMID:23575680]
experiment: EXISTENCE:mutant phenotype:GO:0000730 DNA recombinase assembly [PMID:23575680]
experiment: EXISTENCE:mutant phenotype:GO:0035861 site of double-strand break [PMID:23575680]
experiment: EXISTENCE:mutant phenotype:GO:0045132 meiotic chromosome segregation [PMID:11470404]
experiment: EXISTENCE:physical interaction:GO:0097196 Shu complex [PMID:15654096]
note: Subunit of the Shu complex (aka PCSS complex); Shu complex also includes Psy3, Shu1, Shu2, and promotes error-free DNA repair; Shu complex mediates inhibition of Srs2p anti-recombinase function; promotes formation of Rad51p filaments; Psy3p and Csm2p contain similar DNA-binding regions which work together to form a single DNA binding site; required for accurate chromosome segregation during meiosis
codon start: 1
product: Csm2p
translation: MEYEDLELITIWPSPTKNKLCQFIKQNLSKEHVVTQLFFIDATSSFPLSQFQKLVPPTLPENVRIYENIRINTCLDLEELSAITVKLLQILSMNKINAQRGTEDAVTEPLKIILYINGLEVMFRNSQFKSSPQRSHELLRDTLLKLRVMGNDENENASIRTLLEFPKEQLLDYYLKKNNNTRTSSVRSKRRRIKNGDSLAEYIWKYYADSLFE
SIO_010081: YIL132C
subclass of: SO_0000673
so part of: YIL132C
location: complement(99860..100501)
location: region:99860-100501:-1
so has part: feature:99860-100501:-1:exon

NP_012134.1
type: Protein
SIO_000068: ncbiprotein

S000001394
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:99860-100501:-1:exon

YIL131C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FKH1
locus tag: YIL131C
so part of: sequence
location: complement(<100781..>102235)
location: region:100781-102235:-1
so has part: feature:100781-102235:-1:exon
subclass of: SO_0000010

854675
type: Gene
SIO_000068: ncbigene

position:100781:-1
position: 100781
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:102235:-1
position: 102235
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:100781-102235:-1:exon

YIL131C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FKH1
locus tag: YIL131C
product: forkhead family transcription factor FKH1
transcript id: NM_001179479.1
SIO_010081: YIL131C
subclass of: SO_0000673
so part of: YIL131C
location: complement(<100781..>102235)
location: region:100781-102235:-1
so has part: feature:100781-102235:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:100781-102235:-1:exon

YIL131C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FKH1
locus tag: YIL131C
experiment: EXISTENCE:direct assay:GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding [PMID:10894548|PMID:11562353]
experiment: EXISTENCE:direct assay:GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific [PMID:10894548]
experiment: EXISTENCE:direct assay:GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific [PMID:10894548|PMID:11562353]
experiment: EXISTENCE:direct assay:GO:0003682 chromatin binding [PMID:24504085]
experiment: EXISTENCE:direct assay:GO:0003688 DNA replication origin binding [PMID:22265405|PMID:24504085]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:10747051|PMID:20847055|PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0019237 centromeric DNA binding [PMID:10683251]
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:24504085|PMID:19158363]
experiment: EXISTENCE:genetic interaction:GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific [PMID:10894548]
experiment: EXISTENCE:genetic interaction:GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific [PMID:10894548|PMID:11562353]
experiment: EXISTENCE:genetic interaction:GO:0006338 chromatin remodeling [PMID:17283050]
experiment: EXISTENCE:genetic interaction:GO:0006369 termination of RNA polymerase II transcription [PMID:12702877]
experiment: EXISTENCE:genetic interaction:GO:0007535 donor selection [PMID:12183363|PMID:16809780]
experiment: EXISTENCE:genetic interaction:GO:0034244 negative regulation of transcription elongation by RNA polymerase II [PMID:12702877]
experiment: EXISTENCE:genetic interaction:GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle [PMID:10894548|PMID:17898805]
experiment: EXISTENCE:genetic interaction:GO:0090055 positive regulation of silent mating-type cassette heterochromatin formation [PMID:10747051|PMID:18045995]
experiment: EXISTENCE:genetic interaction:GO:0090282 positive regulation of transcription involved in G2/M transition of mitotic cell cycle [PMID:11562353|PMID:10747051|PMID:10894548|PMID:10959837]
experiment: EXISTENCE:genetic interaction:GO:2000221 negative regulation of pseudohyphal growth [PMID:10747051|PMID:10894548]
experiment: EXISTENCE:mutant phenotype:GO:0006338 chromatin remodeling [PMID:17283050]
experiment: EXISTENCE:mutant phenotype:GO:0006369 termination of RNA polymerase II transcription [PMID:12702877]
experiment: EXISTENCE:mutant phenotype:GO:0007535 donor selection [PMID:12183363|PMID:16809780|PMID:27257873]
experiment: EXISTENCE:mutant phenotype:GO:0031124 mRNA 3'-end processing [PMID:12702877]
experiment: EXISTENCE:mutant phenotype:GO:0032298 positive regulation of DNA-templated DNA replication initiation [PMID:22265405]
experiment: EXISTENCE:mutant phenotype:GO:0034244 negative regulation of transcription elongation by RNA polymerase II [PMID:12702877]
experiment: EXISTENCE:mutant phenotype:GO:0090055 positive regulation of silent mating-type cassette heterochromatin formation [PMID:10747051]
experiment: EXISTENCE:mutant phenotype:GO:0090419 negative regulation of transcription involved in G2/M transition of mitotic cell cycle [PMID:10747051|PMID:18045995]
experiment: EXISTENCE:mutant phenotype:GO:1903468 positive regulation of DNA replication initiation [PMID:26728715]
note: Forkhead family transcription factor; rate-limiting replication origin activator; evolutionarily conserved lifespan regulator; binds multiple chromosomal elements with distinct specificities, cell cycle dynamics; regulates transcription elongation, chromatin silencing at mating loci, expression of G2/M phase genes; facilitates clustering, activation of early-firing replication origins; binds HML recombination enhancer, regulates donor preference during mating-type switching
codon start: 1
product: forkhead family transcription factor FKH1
translation: MSVTSREQKFSGKYSSYTAQDRQGLVNAVTCVLSSSSDPVAVSSDYSNSLSIAREVNAYAKIAGCDWTYYVQKLEVTIGRNTDSLNLNAVPGTVVKKNIDIDLGPAKIVSRKHAAIRFNLESGSWELQIFGRNGAKVNFRRIPTGPDSPPTVLQSGCIIDIGGVQMIFILPEQETIISDYCLNHLMPKLLSTYGTNGNNNPLLRNIIEGSTYLREQRLQEEARLQQLDHLHTPLSSSSDVNPIGDPHGDTIMMEEDEEDENYTRGGIRPNTYTSSSNNAVTNGNVPHIENPSDLSLDENRYIKPPQSYASMITQAILSTPEGSISLADIYKFISDNYAFYRFSQMAWQNSVRHNLSLNKAFEKVPKRAGQQGKGMNWKISDEVRRDFLNKWNAGKLSKIRRGASVTRQLQLHMSKFGEIPAPESSSIDPRGIKAQKVKKSLQATSSILGESAPQLQRTQLTGQISTTTSMDVTTNANVNNSSLS
SIO_010081: YIL131C
subclass of: SO_0000673
so part of: YIL131C
location: complement(100781..102235)
location: region:100781-102235:-1
so has part: feature:100781-102235:-1:exon

NP_012135.1
type: Protein
SIO_000068: ncbiprotein

S000001393
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:100781-102235:-1:exon

YIL130W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ASG1
locus tag: YIL130W
so part of: sequence
location: <102782..>105676
location: region:102782-105676:1
so has part: feature:102782-105676:1:exon
subclass of: SO_0000010

854676
type: Gene
SIO_000068: ncbigene

position:102782:1
position: 102782
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:105676:1
position: 105676
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:102782-105676:1:exon

YIL130W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ASG1
locus tag: YIL130W
product: Asg1p
transcript id: NM_001179478.1
SIO_010081: YIL130W
subclass of: SO_0000673
so part of: YIL130W
location: <102782..>105676
location: region:102782-105676:1
so has part: feature:102782-105676:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:102782-105676:1:exon

YIL130W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ASG1
locus tag: YIL130W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:19111667|PMID:19158363]
note: Zinc cluster protein proposed to be a transcriptional regulator; regulator involved in the stress response; regulates utilization of fatty acids and accumulation of lipids
codon start: 1
product: Asg1p
translation: MPEQAQQGEQSVKRRRVTRACDECRKKKVKCDGQQPCIHCTVYSYECTYKKPTKRTQNSGNSGVLTLGNVTTGPSSSTVVAAAASNPNKLLSNIKTERAILPGASTIPASNNPSKPRKYKTKSTRLQSKIDRYKQIFDEVFPQLPDIDNLDIPVFLQIFHNFKRDSQSFLDDTVKEYTLIVNDSSSPIQPVLSSNSKNSTPDEFLPNMKSDSNSASSNREQDSVDTYSNIPVGREIKIILPPKAIALQFVKSTWEHCCVLLRFYHRPSFIRQLDELYETDPNNYTSKQMQFLPLCYAAIAVGALFSKSIVSNDSSREKFLQDEGYKYFIAARKLIDITNARDLNSIQAILMLIIFLQCSARLSTCYTYIGVAMRSALRAGFHRKLSPNSGFSPIEIEMRKRLFYTIYKLDVYINAMLGLPRSISPDDFDQTLPLDLSDENITEVAYLPENQHSVLSSTGISNEHTKLFLILNEIISELYPIKKTSNIISHETVTSLELKLRNWLDSLPKELIPNAENIDPEYERANRLLHLSFLHVQIILYRPFIHYLSRNMNAENVDPLCYRRARNSIAVARTVIKLAKEMVSNNLLTGSYWYACYTIFYSVAGLLFYIHEAQLPDKDSAREYYDILKDAETGRSVLIQLKDSSMAASRTYNLLNQIFEKLNSKTIQLTALHSSPSNESAFLVTNNSSALKPHLGDSLQPPVFFSSQDTKNSFSLAKSEESTNDYAMANYLNNTPISENPLNEAQQQDQVSQGTTNMSNERDPNNFLSIDIRLDNNGQSNILDATDDVFIRNDGDIPTNSAFDFSSSKSNASNNSNPDTINNNYNNVSGKNNNNNNITNNSNNNHNNNNNDNNNNNNNNNNNNNNNNNSGNSSNNNNNNNNNKNNNDFGIKIDNNSPSYEGFPQLQIPLSQDNLNIEDKEEMSPNIEIKNEQNMTDSNDILGVFDQLDAQLFGKYLPLNYPSE
SIO_010081: YIL130W
subclass of: SO_0000673
so part of: YIL130W
location: 102782..105676
location: region:102782-105676:1
so has part: feature:102782-105676:1:exon

NP_012136.1
type: Protein
SIO_000068: ncbiprotein

S000001392
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:102782-105676:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS909; Autonomously Replicating Sequence
so part of: sequence
location: 105870..106053
location: region:105870-106053:1
so has part: feature:105870-106053:1:region

S000118394
type: SGD
SIO_000068: sgd

position:105870:1
position: 105870
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:106053:1
position: 106053
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:105870-106053:1:region

YIL129C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PAG1
gene: TAO3
locus tag: YIL129C
gene synonym: PAG1
so part of: sequence
location: complement(<106107..>113237)
location: region:106107-113237:-1
so has part: feature:106107-113237:-1:exon
subclass of: SO_0000010

854677
type: Gene
SIO_000068: ncbigene

position:106107:-1
position: 106107
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:113237:-1
position: 113237
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:106107-113237:-1:exon

YIL129C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PAG1
gene: TAO3
locus tag: YIL129C
gene synonym: PAG1
product: Tao3p
transcript id: NM_001179477.3
SIO_010081: YIL129C
subclass of: SO_0000673
so part of: YIL129C
location: complement(<106107..>113237)
location: region:106107-113237:-1
so has part: feature:106107-113237:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:106107-113237:-1:exon

YIL129C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PAG1
gene: TAO3
locus tag: YIL129C
gene synonym: PAG1
experiment: EXISTENCE:direct assay:GO:0000131 incipient cellular bud site [PMID:11854408]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005933 cellular bud [PMID:12972564]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:12972564]
experiment: EXISTENCE:genetic interaction:GO:0007118 budding cell apical bud growth [PMID:12972564]
experiment: EXISTENCE:mutant phenotype:GO:0000902 cell morphogenesis [PMID:11854408]
experiment: EXISTENCE:mutant phenotype:GO:0007114 cell budding [PMID:11854408]
experiment: EXISTENCE:mutant phenotype:GO:0007118 budding cell apical bud growth [PMID:12972564]
note: Component of the RAM signaling network; is involved in regulation of Ace2p activity and cellular morphogenesis, interacts with protein kinase Cbk1p and also with Kic1p
codon start: 1
product: Tao3p
translation: MASRFTFPPQRDQGIGFTFPPTNKAEGSSNNNQISIDIDPSGQDVLEEINEAPLNTFPLHQSVTDAPIIDIPSPTDMSEGTSLNNQLLLRQQQQQGTGEGQALPPTFVEEQSDQNKISMLLPEQKQQRMQESAPPDITAKSVAEDYVTTLRQQMATDWKSPSEYALHILFTKFIRYAENKLNMCLQQLDMAEPPIVEILGEGVDPSFDEIIKSLGHIAKKKPKPVIDAMMFWRKTKSEAANSASEEMEKLLKEYEFEKAHPSQAHFLMNRRLSRSSSNTTSKYKHNNNTNNLPGMKRHVSSSFNNKVPLIKASSSNNSATSSPSIANSQLKSLENTIEVAKEEAFLADRKSLISIYILCRVLNEIVKQASSNEEEDLSDKLEEIVFTQLKTTDPLSISTSLIKSSNWNSFAELLGSMSEKKFLSVSDRFIADLEKIPAYIPPELEPSTHLLILGMRYLKLRNYPLEKFEESADFMKSLSKFFAKTENFPVCLAYAEVTNQLLLPLAGSLTAEVNHPTWVEAMSTLLNTAKRLQADSKYWVSGFKLTVSILCASPPDLFSKQWLSLLEANASKVKSKSLNERIIFAVGLSRLVWVYLYRCPETLNNTTRTLTKLLQLYLNTRKKENWITGDFGLLNPLTDALISIGFLHPNFLMEQALIPLIRQSFNGSNLENINYEKLILTINTYKGLLVTKERPRFPEDDNRLYELNLNNITVNQVQEASSINHTEISDYFYKLFLLLDSSIGSEVWSPENQHQKQSSNAFSPFGFSFSNDNDSSKNKSLYVILFGTIIEAIPCCLSISRTIPYKSTIEILSRNAVHSEVIISSSSQNALRALASKKNPYTLITWFAKYSFDFDEKTQSSYNMSYLSSKEYNRLLILYVELLECWLEEFQSSNKEENKKETGLDGIRLLPIDAEQEESNETEKLEWKNTVTVIEEVEGNGLFFLCSHDAKIRRLGIQILRIIFKFDEAMMEKTEKLSNGHSRSSSHFAADRGTRLIDLLNECNTTTLINPHKATLSAVEKTRFSRLNSKYKRGLLIKLAESEYGVDAALWQRAFPKLLALVFKTCPMAMALCRSIVCIRLVQVHEIILRVANDVDFKLKNVLPETIVNQWKLYLIAACTSLTSTFDQKLHIPSNIPQHGRKKSQQIFTVQHQKIKSAKSIFKMVLPLLNAKYIMIRDAIITGLSSMNINIFKAYVEAIDVFLVAWKEGSSNNQIRVEMFHILTILSPYLKSDMIFNDEWILRKLSEFLQKTKQFLEKDSVQISYEYQSLRSYFAGLILSYYMAVREHPLIDELFPFQARASCFNFLKEWCGYGEYEPISEERYAIMIKNTESGRDRTAITTGIEFQKNRLQMIVLETMVVLCSDPITQTLDDDLELPIVISFDTEDLLAWIEALFDSDNTTVKNLGVRALENLLDKNRENFKLFRDVAFQCVSHHSHPSVAVLYYTTLCKSVLKLDNLVLDEDELVSLGLYGLVADKEDTRTFAVDLLSAVETKLHNSSYTKVFKERLANSSKTVYKSTAKEISSIFAELLSQDLCLRIFSSLVRILDLFPFEIKRDLLVLMVPWVNKFTLKSLEELDTFMVLNNLFYITIDLNDSLPNEVEQLWISLGKGNSFQNIHVSLEYIINSSMNHCNPLFVQYARDIVLYLANIPGGIGLLDTLLNNLEPKYMVPLAKHTFNEPMNNNKYSFLGNIWERLNYNGKRIIFSKAQLSIIFLVNLLTNLSESVKAKIPLLLHMSICLLDHYVPLIHESACKIASTLIFGLAPSHEKSEETVKLLRNKHALWSYDNLMKKGARSPKTMDLLIRNIISIFSDLDEFQVTWQRIALKWATTCSVRHIACRSFQIFRSLLTFLDQEMLRDMLHRLSNTISDGNVDIQGFAMQILMTLNAIMAELDPTNLISFPQLFWSITACLSSIHEQEFIEVLSCLSKFISKIDLDSPDTVQCLVAIFPSNWEGRFDGLQQIVMTGLRSANSLEITWKFLDKLNLLKDSRIIANTESR…
SIO_010081: YIL129C
subclass of: SO_0000673
so part of: YIL129C
location: complement(106107..113237)
location: region:106107-113237:-1
so has part: feature:106107-113237:-1:exon

NP_012137.3
type: Protein
SIO_000068: ncbiprotein

S000001391
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:106107-113237:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS910; Putative replication origin; identified in multiple array studies, not yet confirmed by plasmid-based assay
so part of: sequence
location: 113237..113806
location: region:113237-113806:1
so has part: feature:113237-113806:1:region

S000130158
type: SGD
SIO_000068: sgd

position:113237:1
position: 113237
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:113806:1
position: 113806
reference: sequence
type: ForwardStrandPosition
type: ExactPosition
type: FuzzyPosition

urn:…
SIO_000300: 1
SIO_000628: feature:113237-113806:1:region

YIL128W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MMS19
gene: MET18
locus tag: YIL128W
gene synonym: MMS19
so part of: sequence
location: <113806..>116904
location: region:113806-116904:1
so has part: feature:113806-116904:1:exon
subclass of: SO_0000010

854678
type: Gene
SIO_000068: ncbigene

position:116904:1
position: 116904
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:113806-116904:1:exon

YIL128W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MMS19
gene: MET18
locus tag: YIL128W
gene synonym: MMS19
product: Met18p
transcript id: NM_001179476.1
SIO_010081: YIL128W
subclass of: SO_0000673
so part of: YIL128W
location: <113806..>116904
location: region:113806-116904:1
so has part: feature:113806-116904:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:113806-116904:1:exon

YIL128W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MMS19
gene: MET18
locus tag: YIL128W
gene synonym: MMS19
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0097361 CIA complex [PMID:22678362]
experiment: EXISTENCE:mutant phenotype:GO:0097428 protein maturation by iron-sulfur cluster transfer [PMID:22678362]
note: Component of cytosolic iron-sulfur protein assembly (CIA) machinery; acts at a late step of Fe-S cluster assembly; forms the CIA targeting complex with Cia1p and Cia2p that directs Fe-S cluster incorporation and maturation of a subset of cytosolic and nuclear proteins involved in methionine biosynthesis, DNA replication and repair, transcription, and telomere maintenance; ortholog of human MMS19
codon start: 1
product: Met18p
translation: MTPDELNSAVVTFMANLNIDDSKANETASTVTDSIVHRSIKLLEVVVALKDYFLSENEVERKKALTCLTTILAKTPKDHLSKNECSVIFQFYQSKLDDQALAKEVLEGFAALAPMKYVSINEIAQLLRLLLDNYQQGQHLASTRLWPFKILRKIFDRFFVNGSSTEQVKRINDLFIETFLHVANGEKDPRNLLLSFALNKSITSSLQNVENFKEDLFDVLFCYFPITFKPPKHDPYKISNQDLKTALRSAITATPLFAEDAYSNLLDKLTASSPVVKNDTLLTLLECVRKFGGSSILENWTLLWNALKFEIMQNSEGNENTLLNPYNKDQQSDDVGQYTNYDACLKIINLMALQLYNFDKVSFEKFFTHVLDELKPNFKYEKDLKQTCQILSAIGSGNVEIFNKVISSTFPLFLINTSEVAKLKLLIMNFSFFVDSYIDLFGRTSKESLGTPVPNNKMAEYKDEIIMILSMALTRSSKAEVTIRTLSVIQFTKMIKMKGFLTPEEVSLIIQYFTEEILTDNNKNIYYACLEGLKTISEIYEDLVFEISLKKLLDLLPDCFEEKIRVNDEENIHIETILKIILDFTTSRHILVKESITFLATKLNRVAKISKSREYCFLLISTIYSLFNNNNQNENVLNEEDALALKNAIEPKLFEIITQESAIVSDNYNLTLLSNVLFFTNLKIPQAAHQEELDRYNELFISEGKIRILDTPNVLAISYAKILSALNKNCQFPQKFTVLFGTVQLLKKHAPRMTETEKLGYLELLLVLSNKFVSEKDVIGLFDWKDLSVINLEVMVWLTKGLIMQNSLESSEIAKKFIDLLSNEEIGSLVSKLFEVFVMDISSLKKFKGISWNNNVKILYKQKFFGDIFQTLVSNYKNTVDMTIKCNYLTALSLVLKHTPSQSVGPFINDLFPLLLQALDMPDPEVRVSALETLKDTTDKHHTLITEHVSTIVPLLLSLSLPHKYNSVSVRLIALQLLEMITTVVPLNYCLSYQDDVLSALIPVLSDKKRIIRKQCVDTRQVYYELGQIPFE
SIO_010081: YIL128W
subclass of: SO_0000673
so part of: YIL128W
location: 113806..116904
location: region:113806-116904:1
so has part: feature:113806-116904:1:exon

NP_012138.1
type: Protein
SIO_000068: ncbiprotein

S000001390
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:113806-116904:1:exon

YIL127C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RRT14
locus tag: YIL127C
so part of: sequence
location: complement(<117024..>117644)
location: region:117024-117644:-1
so has part: feature:117024-117644:-1:exon
subclass of: SO_0000010

854679
type: Gene
SIO_000068: ncbigene

position:117024:-1
position: 117024
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:117644:-1
position: 117644
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:117024-117644:-1:exon

YIL127C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RRT14
locus tag: YIL127C
product: Rrt14p
transcript id: NM_001179475.1
SIO_010081: YIL127C
subclass of: SO_0000673
so part of: YIL127C
location: complement(<117024..>117644)
location: region:117024-117644:-1
so has part: feature:117024-117644:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:117024-117644:-1:exon

YIL127C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RRT14
locus tag: YIL127C
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:14562095]
note: hypothetical protein; identified in a screen for mutants with decreased levels of rDNA transcription; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus; predicted to be involved in ribosome biogenesis
codon start: 1
product: Rrt14p
translation: MSSSLSQTSKYQATSVVNGLLSNLLPGVPKIRANNGKTSVNNGSKAQLIDRNLKKRVQLQNRDVHKIKKKCKLVKKKKVKKHKLDKEQLEQLAKHQVLKKHQHEGTLTDHERKYLNKLIKRNSQNLRSWDLEEEVRDELEDIQQSILKDTVSTANTDRSKRRRFKRKQFKEDIKESDFVKDHRYPGLTPGLAPVGLSDEEDSSEED
SIO_010081: YIL127C
subclass of: SO_0000673
so part of: YIL127C
location: complement(117024..117644)
location: region:117024-117644:-1
so has part: feature:117024-117644:-1:exon

NP_012139.1
type: Protein
SIO_000068: ncbiprotein

S000001389
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:117024-117644:-1:exon

YIL126W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: NPS1
gene: STH1
locus tag: YIL126W
gene synonym: NPS1
so part of: sequence
location: <117992..>122071
location: region:117992-122071:1
so has part: feature:117992-122071:1:exon
subclass of: SO_0000010

854680
type: Gene
SIO_000068: ncbigene

position:117992:1
position: 117992
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:122071:1
position: 122071
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:117992-122071:1:exon

YIL126W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: NPS1
gene: STH1
locus tag: YIL126W
gene synonym: NPS1
product: RSC chromatin remodeling complex ATPase subunit STH1
transcript id: NM_001179474.1
SIO_010081: YIL126W
subclass of: SO_0000673
so part of: YIL126W
location: <117992..>122071
location: region:117992-122071:1
so has part: feature:117992-122071:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:117992-122071:1:exon

YIL126W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: NPS1
gene: STH1
locus tag: YIL126W
gene synonym: NPS1
EC number: 3.6.4.12
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:1396591|PMID:1549132]
experiment: EXISTENCE:direct assay:GO:0006337 nucleosome disassembly [PMID:16492771]
experiment: EXISTENCE:direct assay:GO:0006338 chromatin remodeling [PMID:8980231]
experiment: EXISTENCE:direct assay:GO:0006368 transcription elongation by RNA polymerase II promoter [PMID:17081996]
experiment: EXISTENCE:direct assay:GO:0015616 DNA translocase activity [PMID:12183366]
experiment: EXISTENCE:direct assay:GO:0016586 RSC-type complex [PMID:10619019|PMID:12183366]
experiment: EXISTENCE:direct assay:GO:0070577 lysine-acetylated histone binding [PMID:20126658]
experiment: EXISTENCE:direct assay:GO:0140658 ATP-dependent chromatin remodeler activity [PMID:9799253|PMID:12183366]
experiment: EXISTENCE:genetic interaction:GO:0007059 chromosome segregation [PMID:12697820]
experiment: EXISTENCE:mutant phenotype:GO:0006284 base-excision repair [PMID:24674626]
experiment: EXISTENCE:mutant phenotype:GO:0006302 double-strand break repair [PMID:16024655]
experiment: EXISTENCE:mutant phenotype:GO:0007010 cytoskeleton organization [PMID:12072455]
experiment: EXISTENCE:mutant phenotype:GO:0031055 chromatin remodeling at centromere [PMID:12697820]
experiment: EXISTENCE:mutant phenotype:GO:0051321 meiotic cell cycle [PMID:10320476]
note: ATPase component of the RSC chromatin remodeling complex; required for expression of early meiotic genes; promotes base excision repair in chromatin; essential helicase-related protein homologous to Snf2p
codon start: 1
product: RSC chromatin remodeling complex ATPase subunit STH1
translation: MLQEQSELMSTVMNNTPTTVAALAAVAAASETNGKLGSEEQPEITIPKPRSSAQLEQLLYRYRAIQNHPKENKLEIKAIEDTFRNISRDQDIYETKLDTLRKSIDKGFQYDEDLLNKHLVALQLLEKDTDVPDYFLDLPDTKNDNTTAIEVDYSEKKPIKISADFNAKAKSLGLESKFSNATKTALGDPDTEIRISARISNRINELERLPANLGTYSLDDCLEFITKDDLSSRMDTFKIKALVELKSLKLLTKQKSIRQKLINNVASQAHHNIPYLRDSPFTAAAQRSVQIRSKVIVPQTVRLAEELERQQLLEKRKKERNLHLQKINSIIDFIKERQSEQWSRQERCFQFGRLGASLHNQMEKDEQKRIERTAKQRLAALKSNDEEAYLKLLDQTKDTRITQLLRQTNSFLDSLSEAVRAQQNEAKILHGEEVQPITDEEREKTDYYEVAHRIKEKIDKQPSILVGGTLKEYQLRGLEWMVSLYNNHLNGILADEMGLGKTIQSISLITYLYEVKKDIGPFLVIVPLSTITNWTLEFEKWAPSLNTIIYKGTPNQRHSLQHQIRVGNFDVLLTTYEYIIKDKSLLSKHDWAHMIIDEGHRMKNAQSKLSFTISHYYRTRNRLILTGTPLQNNLPELWALLNFVLPKIFNSAKTFEDWFNTPFANTGTQEKLELTEEETLLIIRRLHKVLRPFLLRRLKKEVEKDLPDKVEKVIKCKLSGLQQQLYQQMLKHNALFVGAGTEGATKGGIKGLNNKIMQLRKICNHPFVFDEVEGVVNPSRGNSDLLFRVAGKFELLDRVLPKFKASGHRVLMFFQMTQVMDIMEDFLRMKDLKYMRLDGSTKTEERTEMLNAFNAPDSDYFCFLLSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTDSVEEVILERAMQKLDIDGKVIQAGKFDNKSTAEEQEAFLRRLIESETNRDDDDKAELDDDELNDTLARSADEKILFDKIDKERMNQERADAKAQGLRVPPPRLIQLDELPKVFREDIEEHFKKEDSEPLGRIRQKKRVYYDDGLTEEQFLEAVEDDNMSLEDAIKKRREARERRRLRQNGTKENEIETLENTPEASETSLIENNSFTAAVDEETNADKETTASRSKRRSSRKKRTISIVTAEDKENTQEESTSQENGGAKVEEEVKSSSVEIINGSESKKKKPKLTVKIKLNKTTVLENNDGKRAEEKPESKSPAKKTAAKKTKTKSKSLGIFPTVEKLVEEMREQLDEVDSHPRTSIFEKLPSKRDYPDYFKVIEKPMAIDIILKNCKNGTYKTLEEVRQALQTMFENARFYNEEGSWVYVDADKLNEFTDEWFKEHSS
SIO_010081: YIL126W
subclass of: SO_0000673
so part of: YIL126W
location: 117992..122071
location: region:117992-122071:1
so has part: feature:117992-122071:1:exon

NP_012140.1
type: Protein
SIO_000068: ncbiprotein

S000001388
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:117992-122071:1:exon

YIL125W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: OGD1
gene: KGD1
locus tag: YIL125W
gene synonym: OGD1
so part of: sequence
location: <122689..>125733
location: region:122689-125733:1
so has part: feature:122689-125733:1:exon
subclass of: SO_0000010

854681
type: Gene
SIO_000068: ncbigene

position:122689:1
position: 122689
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:125733:1
position: 125733
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:122689-125733:1:exon

YIL125W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: OGD1
gene: KGD1
locus tag: YIL125W
gene synonym: OGD1
product: alpha-ketoglutarate dehydrogenase KGD1
transcript id: NM_001179473.1
SIO_010081: YIL125W
subclass of: SO_0000673
so part of: YIL125W
location: <122689..>125733
location: region:122689-125733:1
so has part: feature:122689-125733:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:122689-125733:1:exon

YIL125W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: OGD1
gene: KGD1
locus tag: YIL125W
gene synonym: OGD1
EC number: 1.2.4.2
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0009353 mitochondrial oxoglutarate dehydrogenase complex [PMID:2072900]
experiment: EXISTENCE:direct assay:GO:0042645 mitochondrial nucleoid [PMID:11926067|PMID:15692048]
note: Subunit of the mitochondrial alpha-ketoglutarate dehydrogenase complex; catalyzes a key step in the tricarboxylic acid (TCA) cycle, the oxidative decarboxylation of alpha-ketoglutarate to form succinyl-CoA
codon start: 1
product: alpha-ketoglutarate dehydrogenase KGD1
translation: MLRFVSSQTCRYSSRGLLKTSLLKNASTVKIVGRGLATTGTDNFLSTSNATYIDEMYQAWQKDPSSVHVSWDAYFKNMSNPKIPATKAFQAPPSISNFPQGTEAAPLGTAMTGSVDENVSIHLKVQLLCRAYQVRGHLKAHIDPLGISFGSNKNNPVPPELTLDYYGFSKHDLDKEINLGPGILPRFARDGKSKMSLKEIVDHLEKLYCSSYGVQYTHIPSKQKCDWLRERIEIPEPYQYTVDQKRQILDRLTWATSFESFLSTKFPNDKRFGLEGLESVVPGIKTLVDRSVELGVEDIVLGMAHRGRLNVLSNVVRKPNESIFSEFKGSSARDDIEGSGDVKYHLGMNYQRPTTSGKYVNLSLVANPSHLESQDPVVLGRTRALLHAKNDLKEKTKALGVLLHGDAAFAGQGVVYETMGFLTLPEYSTGGTIHVITNNQIGFTTDPRFARSTPYPSDLAKAIDAPIFHVNANDVEAVTFIFNLAAEWRHKFHTDAIIDVVGWRKHGHNETDQPSFTQPLMYKKIAKQKSVIDVYTEKLISEGTFSKKDIDEHKKWVWNLFEDAFEKAKDYVPSQREWLTAAWEGFKSPKELATEILPHEPTNVPESTLKELGKVLSSWPEGFEVHKNLKRILKNRGKSIETGEGIDWATGEALAFGTLVLDGQNVRVSGEDVERGTFSQRHAVLHDQQSEAIYTPLSTLNNEKADFTIANSSLSEYGVMGFEYGYSLTSPDYLVMWEAQFGDFANTAQVIIDQFIAGGEQKWKQRSGLVLSLPHGYDGQGPEHSSGRLERFLQLANEDPRYFPSEEKLQRQHQDCNFQVVYPTTPANLFHILRRQQHRQFRKPLALFFSKQLLRHPLARSSLSEFTEGGFQWIIEDIEHGKSIGTKEETKRLVLLSGQVYTALHKRRESLGDKTTAFLKIEQLHPFPFAQLRDSLNSYPNLEEIVWCQEEPLNMGSWAYTEPRLHTTLKETDKYKDFKVRYCGRNPSGAVAAGSKSLHLAEEDAFLKDVFQQS
SIO_010081: YIL125W
subclass of: SO_0000673
so part of: YIL125W
location: 122689..125733
location: region:122689-125733:1
so has part: feature:122689-125733:1:exon

NP_012141.1
type: Protein
SIO_000068: ncbiprotein

S000001387
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:122689-125733:1:exon

YIL124W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: GBG1
gene: AYR1
locus tag: YIL124W
gene synonym: GBG1
so part of: sequence
location: <126204..>127097
location: region:126204-127097:1
so has part: feature:126204-127097:1:exon
subclass of: SO_0000010

854682
type: Gene
SIO_000068: ncbigene

position:126204:1
position: 126204
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:127097:1
position: 127097
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:126204-127097:1:exon

YIL124W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: GBG1
gene: AYR1
locus tag: YIL124W
gene synonym: GBG1
product: acylglycerone-phosphate reductase
transcript id: NM_001179472.3
SIO_010081: YIL124W
subclass of: SO_0000673
so part of: YIL124W
location: <126204..>127097
location: region:126204-127097:1
so has part: feature:126204-127097:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:126204-127097:1:exon

YIL124W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: GBG1
gene: AYR1
locus tag: YIL124W
gene synonym: GBG1
EC number: 1.1.1.101
EC number: 3.1.1.3
experiment: EXISTENCE:direct assay:GO:0004806 triglyceride lipase activity [PMID:24187129]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005741 mitochondrial outer membrane [PMID:16407407]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:10617610|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005811 lipid droplet [PMID:10617610|PMID:24868093]
experiment: EXISTENCE:genetic interaction:GO:0004806 triglyceride lipase activity [PMID:24187129]
experiment: EXISTENCE:genetic interaction:GO:0019433 triglyceride catabolic process [PMID:24187129]
experiment: EXISTENCE:mutant phenotype:GO:0000140 acylglycerone-phosphate reductase activity [PMID:10617610]
experiment: EXISTENCE:mutant phenotype:GO:0004806 triglyceride lipase activity [PMID:24187129]
experiment: EXISTENCE:mutant phenotype:GO:0006654 phosphatidic acid biosynthetic process [PMID:10617610]
note: Bifunctional triacylglycerol lipase and 1-acyl DHAP reductase; NADPH-dependent 1-acyl dihydroxyacetone phosphate reductase involved in phosphatidic acid biosynthesis; lipid droplet triacylglycerol lipase involved in mobilization of non-polar lipids; found in lipid particles, endoplasmic reticulum and mitochondrial outer membrane; forms NADPH-regulated channel in mitochondrial outer membrane; required for spore germination; role in cell wall biosynthesis; capable of metabolizing steroid hormones
codon start: 1
product: acylglycerone-phosphate reductase
translation: MSELQSQPKKIAVVTGASGGIGYEVTKELARNGYLVYACARRLEPMAQLAIQFGNDSIKPYKLDISKPEEIVTFSGFLRANLPDGKLDLLYNNAGQSCTFPALDATDAAVEQCFKVNVFGHINMCRELSEFLIKAKGTIVFTGSLAGVVSFPFGSIYSASKAAIHQYARGLHLEMKPFNVRVINAITGGVATDIADKRPLPETSIYNFPEGREAFNSRKTMAKDNKPMPADAYAKQLVKDILSTSDPVDVYRGTFANIMRFVMIFVPYWLLEKGLSKKFKLDKVNNALKSKQKNKDD
SIO_010081: YIL124W
subclass of: SO_0000673
so part of: YIL124W
location: 126204..127097
location: region:126204-127097:1
so has part: feature:126204-127097:1:exon

NP_012142.3
type: Protein
SIO_000068: ncbiprotein

S000001386
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:126204-127097:1:exon

YIL123W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SIM1
locus tag: YIL123W
so part of: sequence
location: <128151..>129581
location: region:128151-129581:1
so has part: feature:128151-129581:1:exon
subclass of: SO_0000010

854683
type: Gene
SIO_000068: ncbigene

position:128151:1
position: 128151
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:129581:1
position: 129581
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:128151-129581:1:exon

YIL123W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SIM1
locus tag: YIL123W
product: putative glucosidase SIM1
transcript id: NM_001179471.2
SIO_010081: YIL123W
subclass of: SO_0000673
so part of: YIL123W
location: <128151..>129581
location: region:128151-129581:1
so has part: feature:128151-129581:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:128151-129581:1:exon

YIL123W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SIM1
locus tag: YIL123W
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0009277 fungal-type cell wall [PMID:11958935]
experiment: EXISTENCE:mutant phenotype:GO:0031505 fungal-type cell wall organization [PMID:15972461]
note: Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p); may participate in DNA replication; promoter contains SCB regulation box at -300 bp indicating that expression may be cell cycle-regulated; SIM1 has a paralog, SUN4, that arose from the whole genome duplication
codon start: 1
product: putative glucosidase SIM1
translation: MKFSTAVTTLISSGAIVSALPHVDVHQEDAHQHKRAVAYKYVYETVVVDSDGHTVTPAASEVATAATSAIITTSVLAPTSSAAAADSSASIAVSSAALAKNEKISDAAASATASTSQGASSSSSSSSATSTLESSSVSSSSEEAAPTSTVVSTSSATQSSASSATKSSTSSTSPSTSTSTSTSSTSSSSSSSSSSSSSSSGSGSIYGDLADFSGPSEKFQDGTIPCDKFPSGQGVISIDWIGEGGWSGVENTDTSTGGSCKEGSYCSYSCQPGMSKTQWPSDQPSDGRSVGGLLCKNGYLYRSNTDADYLCEWGVEAAYVVSKLSKGVAICRTDYPGTENMVIPTYVEGGSSLPLTVVDQDTYFTWEGKKTSAQYYVNNAGVSVEDGCIWGTSGSGIGNWAPLNFGAGSTGGVTYLSLIPNPNNSDALNYNVKIVAADDSSNVIGECVYENGEFSGGADGCTVSVTSGKAHFVLYN
SIO_010081: YIL123W
subclass of: SO_0000673
so part of: YIL123W
location: 128151..129581
location: region:128151-129581:1
so has part: feature:128151-129581:1:exon

NP_012143.2
type: Protein
SIO_000068: ncbiprotein

S000001385
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:128151-129581:1:exon

YIL122W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: POG1
locus tag: YIL122W
so part of: sequence
location: <130610..>131665
location: region:130610-131665:1
so has part: feature:130610-131665:1:exon
subclass of: SO_0000010

854684
type: Gene
SIO_000068: ncbigene

position:130610:1
position: 130610
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:131665:1
position: 131665
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:130610-131665:1:exon

YIL122W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: POG1
locus tag: YIL122W
product: Pog1p
transcript id: NM_001179470.1
SIO_010081: YIL122W
subclass of: SO_0000673
so part of: YIL122W
location: <130610..>131665
location: region:130610-131665:1
so has part: feature:130610-131665:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:130610-131665:1:exon

YIL122W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: POG1
locus tag: YIL122W
experiment: EXISTENCE:direct assay:GO:0000785 chromatin [PMID:12464632]
experiment: EXISTENCE:direct assay:GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding [PMID:22959267]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:11914276]
experiment: EXISTENCE:genetic interaction:GO:0000321 re-entry into mitotic cell cycle after pheromone arrest [PMID:9927449]
experiment: EXISTENCE:mutant phenotype:GO:0000321 re-entry into mitotic cell cycle after pheromone arrest [PMID:9927449]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:22959267|PMID:9927449]
note: DNA-binding transcriptional activator; involved in cell cycle regulation; overexpression promotes recovery from pheromone induced arrest via CLN1/2 transcription, induction of of IME1 during sporulation, and suppression of stress sensitivity resulting from mutation of the E3 ubiquitin ligase Rsp5p; binds upstream of BAR1 and cell cycle-related genes; phosphorylated form may be ubiquitinated by Dma2p; potential Cdc28p substrate; regulated by Swi4/6 cell-cycle box binding factor (SBF)
codon start: 1
product: Pog1p
translation: MKQEPHRQSEEKEKPKGPMAVEREQHTSLSSGTTVTASTGDESTNSRPVESSQTEKSLSLRIRILKQLGFDDIQELNACDTGLVEQFLNVRLINDTKELEKIRESNLAKLNQIIDKCMESDKISDSTLNKILDMSMNRDTNNDNNNHLTIPSPITTKKRKINASELASPRGHRRYRSDIPTVSEVETGVGYPQIHQQPGAYTLPMPANQWMSNPYMQPPQPQVQQIMPQYLYPPGMGPQAQLPTMSSNSESQTPVMSSQFLSLNQHGLYQQNIGAHPVMSMGPQANIYGQQHQLQPGQERDQSRKSFSHRRSQSANISMANFRSPMRNPQPASSQRPVNFLIHTPKHPPPT
SIO_010081: YIL122W
subclass of: SO_0000673
so part of: YIL122W
location: 130610..131665
location: region:130610-131665:1
so has part: feature:130610-131665:1:exon

NP_012144.1
type: Protein
SIO_000068: ncbiprotein

S000001384
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:130610-131665:1:exon

YIL121W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: QDR2
locus tag: YIL121W
so part of: sequence
location: <132244..>133872
location: region:132244-133872:1
so has part: feature:132244-133872:1:exon
subclass of: SO_0000010

854685
type: Gene
SIO_000068: ncbigene

position:132244:1
position: 132244
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:133872:1
position: 133872
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:132244-133872:1:exon

YIL121W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: QDR2
locus tag: YIL121W
product: cation transporter
transcript id: NM_001179469.1
SIO_010081: YIL121W
subclass of: SO_0000673
so part of: YIL121W
location: <132244..>133872
location: region:132244-133872:1
so has part: feature:132244-133872:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:132244-133872:1:exon

YIL121W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: QDR2
locus tag: YIL121W
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:15215105|PMID:34887841]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:1990573 potassium ion import across plasma membrane [PMID:17189489]
experiment: EXISTENCE:mutant phenotype:GO:0008324 cation transmembrane transporter activity [PMID:23106982]
experiment: EXISTENCE:mutant phenotype:GO:0015565 threonine efflux transmembrane transporter activity [PMID:34887841]
experiment: EXISTENCE:mutant phenotype:GO:0032973 amino acid export across plasma membrane [PMID:34887841]
experiment: EXISTENCE:mutant phenotype:GO:0042910 xenobiotic transmembrane transporter activity [PMID:15215105|PMID:15649438]
experiment: EXISTENCE:mutant phenotype:GO:0055085 transmembrane transport [PMID:15215105|PMID:15649438]
experiment: EXISTENCE:mutant phenotype:GO:0060003 copper ion export [PMID:23106982]
experiment: EXISTENCE:mutant phenotype:GO:1990573 potassium ion import across plasma membrane [PMID:17189489]
note: Plasma membrane transporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; exports copper; has broad substrate specificity and can transport many mono- and divalent cations; transports a variety of drugs and is required for resistance to quinidine, barban, cisplatin, and bleomycin; contributes to potassium homeostasis; expression is regulated by copper
codon start: 1
product: cation transporter
translation: MAGATSSIIRENDFEDELAESMQSYNRETADKLALTRTESVKPEPEITAPPHSRFSRSFKTVLIAQCAFTGFFSTIAGAIYYPVLSVIERKFDIDEELVNVTVVVYFVFQGLAPTFMGGFADSLGRRPVVLVAIVIYFGACIGLACAQTYAQIIVLRCLQAAGISPVIAINSGIMGDVTTRAERGGYVGYVAGFQVLGSAFGALIGAGLSSRWGWRAIFWFLAIGSGICFLASFLILPETKRNISGNGSVTPKSYLNRAPILVLPTVRKSLHLDNPDYETLELPTQLNLLAPFKILKAYEICILMLVAGLQFAMYTTHLTALSTALSKQYHLTVAKVGLCYLPSGICTLCSIVIAGRYLNWNYRRRLKYYQNWLGKKRSKLLEEHDNDLNLVQRIIENDPKYTFNIFKARLQPAFVTLLLSSSGFCAYGWCITVKAPLAAVLCMSGFASLFSNCILTFSTTLIVDLFPTKTSTATGCLNLFRCILSAVFIAALSKMVEKMKFGGVFTFLGALTSSSSILLFILLRKGKELAFKRKKQELGVN
SIO_010081: YIL121W
subclass of: SO_0000673
so part of: YIL121W
location: 132244..133872
location: region:132244-133872:1
so has part: feature:132244-133872:1:exon

NP_012145.1
type: Protein
SIO_000068: ncbiprotein

S000001383
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:132244-133872:1:exon

YIL120W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: QDR1
locus tag: YIL120W
so part of: sequence
location: <134417..>136108
location: region:134417-136108:1
so has part: feature:134417-136108:1:exon
subclass of: SO_0000010

854686
type: Gene
SIO_000068: ncbigene

position:134417:1
position: 134417
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:136108:1
position: 136108
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:134417-136108:1:exon

YIL120W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: QDR1
locus tag: YIL120W
product: multidrug transporter
transcript id: NM_001179468.1
SIO_010081: YIL120W
subclass of: SO_0000673
so part of: YIL120W
location: <134417..>136108
location: region:134417-136108:1
so has part: feature:134417-136108:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:134417-136108:1:exon

YIL120W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: QDR1
locus tag: YIL120W
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:11302822]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0030476 ascospore wall assembly [PMID:23966878]
experiment: EXISTENCE:mutant phenotype:GO:0015562 efflux transmembrane transporter activity [PMID:15649438]
experiment: EXISTENCE:mutant phenotype:GO:0055085 transmembrane transport [PMID:15649438]
note: Multidrug transporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; involved in spore wall assembly; sequence similarity to DTR1 and QDR3, and the triple mutant dtr1 qdr1 qdr3 exhibits reduced dityrosine fluorescence relative to the single mutants; required for resistance to quinidine, ketoconazole, fluconazole, and barban; QDR1 has a paralog, AQR1, that arose from the whole genome duplication
codon start: 1
product: multidrug transporter
translation: MTKQQTSVMRNASIAKEEREGSDNNNVDRSSSDAISDNDAERSNSHSEIDNESNFDMVPYSRFSHKQKMLLVVQCAFTGFFSTVAGSIYYPVLTIIERKFNITEELANVTIVVYFIFQGVAPSIMGGLADTFGRRPIVLWAILAYFCACIGLACAHNYAQILALRCLQAAGISPVIAINSGIMGDVTTKVERGGYVGLVAGFQVVGTAFGALIGAGLSSKWGWRAIFWFLAIGSGICLVFSTLLMPETKRTLVGNGSVTPRSFLNRSLILHVGSVKKTLHLDDPDPETLEPRTSVDFLAPLKILHIREIDILLSIAGLQFSTWTTHQTALTIVLSKKYNLSVAKIGLCFLPAGISTLTSIISAGRYLNWSYRTRKVKYNRWIKEQELQLMEKYKGDKNKVAELIHSNSHYAFNLVEARLHPAFVTLLLSSIGFTAFGWCISVKTPLAAVLCTSAFASLFSNCILTFSTTLIVDLFPSKASTATGCLNLFRCLLSAIFIAALTKMVEKMRYGGVFTFLSAITSSSSLLLFYLLKNGKQLSFDRIRANDKSAGRSVGKNSEKVST
SIO_010081: YIL120W
subclass of: SO_0000673
so part of: YIL120W
location: 134417..136108
location: region:134417-136108:1
so has part: feature:134417-136108:1:exon

NP_012146.1
type: Protein
SIO_000068: ncbiprotein

S000001382
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:134417-136108:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS911; Autonomously Replicating Sequence
so part of: sequence
location: 136098..136338
location: region:136098-136338:1
so has part: feature:136098-136338:1:region

S000118395
type: SGD
SIO_000068: sgd

position:136098:1
position: 136098
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:136338:1
position: 136338
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:136098-136338:1:region

YIL119C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RPI1
locus tag: YIL119C
so part of: sequence
location: complement(<136654..>137877)
location: region:136654-137877:-1
so has part: feature:136654-137877:-1:exon
subclass of: SO_0000010

854687
type: Gene
SIO_000068: ncbigene

position:136654:-1
position: 136654
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:137877:-1
position: 137877
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:136654-137877:-1:exon

YIL119C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RPI1
locus tag: YIL119C
product: Rpi1p
transcript id: NM_001179467.3
SIO_010081: YIL119C
subclass of: SO_0000673
so part of: YIL119C
location: complement(<136654..>137877)
location: region:136654-137877:-1
so has part: feature:136654-137877:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:136654-137877:-1:exon

YIL119C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RPI1
locus tag: YIL119C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:12455971]
experiment: EXISTENCE:genetic interaction:GO:0009272 fungal-type cell wall biogenesis [PMID:12455971]
experiment: EXISTENCE:mutant phenotype:GO:0007265 Ras protein signal transduction [PMID:1649384]
experiment: EXISTENCE:mutant phenotype:GO:0009272 fungal-type cell wall biogenesis [PMID:12455971]
experiment: EXISTENCE:mutant phenotype:GO:0030695 GTPase regulator activity [PMID:1649384]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:12455971]
note: Transcription factor, allelic differences between S288C and Sigma1278b; mediates fermentation stress tolerance by modulating cell wall integrity; overexpression suppresses heat shock sensitivity of wild-type RAS2 overexpression and also suppresses cell lysis defect of mpk1 mutation; allele from S288c can confer fMAPK pathway independent transcription of FLO11; S288C and Sigma1278b alleles differ in number of tandem repeats within ORF
codon start: 1
product: Rpi1p
translation: MYLEYLQPKLNLMDESSTISKNFPDYSPNLNTPITSNFNEETGSDCSLVTPRIISSSNSNSNSNSNSNSNSNSGSIDENELNNSNSSSSSARQIRKKWKEPEDIAFITTIMNNSQLLTFVEYFKPMKNFWKKISKILFQQYGYERNSRQCHDRFKVLYTKSLKVHPSKKSKQKKKKSKQEAGSNLNFDPSKLSRMQYLLVQLQNTFSFVNGNIILKSQKTLKPNKNGTNDNINNHYYNNCNNNNNNINNSNNSNNNNSNNINRNSNHSTNVFSTPEHIQSSINLDKLESLPALDTKGEPSFISPAQFSLLSSAPADNLILQTPPSPFFQQTMPIQLPRDAQQEQISPVFSTDVIYMWQTMFNTIENLKEQVNCLKNEVKQLNHKFYQQNKPLHNMSTSDSENFMQQH
SIO_010081: YIL119C
subclass of: SO_0000673
so part of: YIL119C
location: complement(136654..137877)
location: region:136654-137877:-1
so has part: feature:136654-137877:-1:exon

NP_012147.3
type: Protein
SIO_000068: ncbiprotein

S000001381
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:136654-137877:-1:exon

YIL118W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RHO3
locus tag: YIL118W
so part of: sequence
location: <139752..>140447
location: region:139752-140447:1
so has part: feature:139752-140447:1:exon
subclass of: SO_0000010

854688
type: Gene
SIO_000068: ncbigene

position:139752:1
position: 139752
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:140447:1
position: 140447
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:139752-140447:1:exon

YIL118W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RHO3
locus tag: YIL118W
product: Rho family GTPase RHO3
transcript id: NM_001179466.1
SIO_010081: YIL118W
subclass of: SO_0000673
so part of: YIL118W
location: <139752..>140447
location: region:139752-140447:1
so has part: feature:139752-140447:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:139752-140447:1:exon

YIL118W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RHO3
locus tag: YIL118W
experiment: EXISTENCE:direct assay:GO:0003924 GTPase activity [PMID:10526184]
experiment: EXISTENCE:direct assay:GO:0005525 GTP binding [PMID:10207081]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:10207081]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:16622836]
experiment: EXISTENCE:direct assay:GO:0005933 cellular bud [PMID:10207081]
experiment: EXISTENCE:genetic interaction:GO:0045921 positive regulation of exocytosis [PMID:8852836|PMID:19955214]
experiment: EXISTENCE:genetic interaction:GO:0090338 positive regulation of formin-nucleated actin cable assembly [PMID:12810699]
experiment: EXISTENCE:mutant phenotype:GO:0030950 establishment or maintenance of actin cytoskeleton polarity [PMID:10588647|PMID:8852836]
experiment: EXISTENCE:mutant phenotype:GO:0045921 positive regulation of exocytosis [PMID:10588647]
experiment: EXISTENCE:mutant phenotype:GO:0090338 positive regulation of formin-nucleated actin cable assembly [PMID:12810699]
experiment: EXISTENCE:physical interaction:GO:0045921 positive regulation of exocytosis [PMID:19955214]
note: Non-essential small GTPase of the Rho/Rac family of Ras-like proteins; involved in the establishment of cell polarity; GTPase activity positively regulated by the GTPase activating protein (GAP) Rgd1p
codon start: 1
product: Rho family GTPase RHO3
translation: MSFLCGSASTSNKPIERKIVILGDGACGKTSLLNVFTRGYFPEVYEPTVFENYIHDIFVDSKHITLSLWDTAGQEEFDRLRSLSYSDTQCIMLCFSIDSRDSLENVQNKWVGEITDHCEGVKLVLVALKCDLRNNENESNAITPNNIQQDNSVSNDNGNNINSTSNGKNLISYEEGLAMAKKIGALRYLECSAKLNKGVNEAFTEAARVALTAGPVATEVKSDSGSSCTIM
SIO_010081: YIL118W
subclass of: SO_0000673
so part of: YIL118W
location: 139752..140447
location: region:139752-140447:1
so has part: feature:139752-140447:1:exon

NP_012148.1
type: Protein
SIO_000068: ncbiprotein

S000001380
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:139752-140447:1:exon

YIL117C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PRM5
locus tag: YIL117C
so part of: sequence
location: complement(<140613..>141569)
location: region:140613-141569:-1
so has part: feature:140613-141569:-1:exon
subclass of: SO_0000010

854689
type: Gene
SIO_000068: ncbigene

position:140613:-1
position: 140613
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:141569:-1
position: 141569
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:140613-141569:-1:exon

YIL117C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PRM5
locus tag: YIL117C
product: pheromone-regulated protein PRM5
transcript id: NM_001179465.1
SIO_010081: YIL117C
subclass of: SO_0000673
so part of: YIL117C
location: complement(<140613..>141569)
location: region:140613-141569:-1
so has part: feature:140613-141569:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:140613-141569:-1:exon

YIL117C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PRM5
locus tag: YIL117C
note: Pheromone-regulated protein, predicted to have 1 transmembrane segment; induced during cell integrity signaling; PRM5 has a paralog, YNL058C, that arose from the whole genome duplication
codon start: 1
product: pheromone-regulated protein PRM5
translation: MTVITIAKRGLPKLTTSTSSTTTASSSSTITSVASSSSSLPLLSNSTSSSIIPSITPPSRNGNPYILDSGDMPNGTVFIVVGGIAGVIFLAILLWWVITTYSSHRLTRSVQDYESKMFSTQHTQFYGDSPYMDYPAKENFQDQVHISESDISPGNKDESVKDALVSHTNNEKPFLSNFERPLFSLASESNRNSLFISPTGDILYKTRLSKLYQESPRLLQKPVIMTSDNVSTNSLVSTISSSSASSLDNGNEKEVGEDIRKPAKIASSPSRKLLNSPESDGSVNRNHSKGNLLVVQSKRKPTPSTYLEHMLEGKEQDE
SIO_010081: YIL117C
subclass of: SO_0000673
so part of: YIL117C
location: complement(140613..141569)
location: region:140613-141569:-1
so has part: feature:140613-141569:-1:exon

NP_012149.1
type: Protein
SIO_000068: ncbiprotein

S000001379
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:140613-141569:-1:exon

YIL116W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HIS5
locus tag: YIL116W
so part of: sequence
location: <142928..>144085
location: region:142928-144085:1
so has part: feature:142928-144085:1:exon
subclass of: SO_0000010

854690
type: Gene
SIO_000068: ncbigene

position:142928:1
position: 142928
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:144085:1
position: 144085
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:142928-144085:1:exon

YIL116W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HIS5
locus tag: YIL116W
product: histidinol-phosphate transaminase
transcript id: NM_001179464.1
SIO_010081: YIL116W
subclass of: SO_0000673
so part of: YIL116W
location: <142928..>144085
location: region:142928-144085:1
so has part: feature:142928-144085:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:142928-144085:1:exon

YIL116W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: HIS5
locus tag: YIL116W
EC number: 2.6.1.9
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0000105 histidine biosynthetic process [PMID:14190241]
experiment: EXISTENCE:mutant phenotype:GO:0004400 histidinol-phosphate transaminase activity [PMID:14190241]
note: Histidinol-phosphate aminotransferase; catalyzes the seventh step in histidine biosynthesis; responsive to general control of amino acid biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts
codon start: 1
product: histidinol-phosphate transaminase
translation: MVFDLKRIVRPKIYNLEPYRCARDDFTEGILLDANENAHGPTPVELSKTNLHRYPDPHQLEFKTAMTKYRNKTSSYANDPEVKPLTADNLCLGVGSDESIDAIIRACCVPGKEKILVLPPTYSMYSVCANINDIEVVQCPLTVSDGSFQMDTEAVLTILKNDSLIKLMFVTSPGNPTGAKIKTSLIEKVLQNWDNGLVVVDEAYVDFCGGSTAPLVTKYPNLVTLQTLSKSFGLAGIRLGMTYATAELARILNAMKAPYNISSLASEYALKAVQDSNLKKMEATSKIINEEKMRLLKELTALDYVDDQYVGGLDANFLLIRINGGDNVLAKKLYYQLATQSGVVVRFRGNELGCSGCLRITVGTHEENTHLIKYFKETLYKLANE
SIO_010081: YIL116W
subclass of: SO_0000673
so part of: YIL116W
location: 142928..144085
location: region:142928-144085:1
so has part: feature:142928-144085:1:exon

NP_012150.1
type: Protein
SIO_000068: ncbiprotein

S000001378
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:142928-144085:1:exon

YIL115C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: NUP158
alternative label: RAT7
gene: NUP159
locus tag: YIL115C
gene synonym: NUP158; RAT7
so part of: sequence
location: complement(<144327..>148709)
location: region:144327-148709:-1
so has part: feature:144327-148709:-1:exon
subclass of: SO_0000010

854691
type: Gene
SIO_000068: ncbigene

position:144327:-1
position: 144327
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:148709:-1
position: 148709
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:144327-148709:-1:exon

YIL115C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: NUP158
alternative label: RAT7
gene: NUP159
locus tag: YIL115C
gene synonym: NUP158; RAT7
product: FG-nucleoporin NUP159
transcript id: NM_001179463.1
SIO_010081: YIL115C
subclass of: SO_0000673
so part of: YIL115C
location: complement(<144327..>148709)
location: region:144327-148709:-1
so has part: feature:144327-148709:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:144327-148709:-1:exon

YIL115C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: NUP158
alternative label: RAT7
gene: NUP159
locus tag: YIL115C
gene synonym: NUP158; RAT7
experiment: EXISTENCE:direct assay:GO:0000774 adenyl-nucleotide exchange factor activity [PMID:21576266]
experiment: EXISTENCE:direct assay:GO:0005643 nuclear pore [PMID:10684247|PMID:7642562|PMID:7744966]
experiment: EXISTENCE:direct assay:GO:0044613 nuclear pore central transport channel [PMID:18046406]
experiment: EXISTENCE:direct assay:GO:0044614 nuclear pore cytoplasmic filaments [PMID:10684247|PMID:14960378]
experiment: EXISTENCE:direct assay:GO:0061912 selective autophagy [PMID:32029894]
experiment: EXISTENCE:genetic interaction:GO:0006607 NLS-bearing protein import into nucleus [PMID:15039779]
experiment: EXISTENCE:genetic interaction:GO:0016973 poly(A)+ mRNA export from nucleus [PMID:10952996]
experiment: EXISTENCE:mutant phenotype:GO:0000055 ribosomal large subunit export from nucleus [PMID:11071906|PMID:11739405]
experiment: EXISTENCE:mutant phenotype:GO:0000056 ribosomal small subunit export from nucleus [PMID:11739405]
experiment: EXISTENCE:mutant phenotype:GO:0000774 adenyl-nucleotide exchange factor activity [PMID:21576266]
experiment: EXISTENCE:mutant phenotype:GO:0006611 protein export from nucleus [PMID:17347149]
experiment: EXISTENCE:mutant phenotype:GO:0016973 poly(A)+ mRNA export from nucleus [PMID:27385342|PMID:7744966|PMID:9359887|PMID:9802895|PMID :15574330]
experiment: EXISTENCE:mutant phenotype:GO:0051664 nuclear pore localization [PMID:9359887|PMID:7744966]
experiment: EXISTENCE:mutant phenotype:GO:0097064 ncRNA export from nucleus [PMID:11352936]
experiment: EXISTENCE:physical interaction:GO:0017056 structural constituent of nuclear pore [PMID:17418788]
note: FG-nucleoporin component of central core of the nuclear pore complex; also part of the nuclear pore complex (NPC) cytoplasmic filaments; contributes directly to nucleocytoplasmic transport; regulates ADP release from the ATP-dependent RNA helicase Dbp5p; forms a stable association with Nup82p, Gle2p and two other FG-nucleoporins (Nsp1p and Nup116p)
codon start: 1
product: FG-nucleoporin NUP159
translation: MSSLKDEVPTETSEDFGFKFLGQKQILPSFNEKLPFASLQNLDISNSKSLFVAASGSKAVVGELQLLRDHITSDSTPLTFKWEKEIPDVIFVCFHGDQVLVSTRNALYSLDLEELSEFRTVTSFEKPVFQLKNVNNTLVILNSVNDLSALDLRTKSTKQLAQNVTSFDVTNSQLAVLLKDRSFQSFAWRNGEMEKQFEFSLPSELEELPVEEYSPLSVTILSPQDFLAVFGNVISETDDEVSYDQKMYIIKHIDGSASFQETFDITPPFGQIVRFPYMYKVTLSGLIEPDANVNVLASSCSSEVSIWDSKQVIEPSQDSERAVLPISEETDKDTNPIGVAVDVVTSGTILEPCSGVDTIERLPLVYILNNEGSLQIVGLFHVAAIKSGHYSINLESLEHEKSLSPTSEKIPIAGQEQEEKKKNNESSKALSENPFTSANTSGFTFLKTQPAAANSLQSQSSSTFGAPSFGSSAFKIDLPSVSSTSTGVASSEQDATDPASAKPVFGKPAFGAIAKEPSTSEYAFGKPSFGAPSFGSGKSSVESPASGSAFGKPSFGTPSFGSGNSSVEPPASGSAFGKPSFGTPSFGSGNSSAEPPASGSAFGKPSFGTSAFGTASSNETNSGSIFGKAAFGSSSFAPANNELFGSNFTISKPTVDSPKEVDSTSPFPSSGDQSEDESKSDVDSSSTPFGTKPNTSTKPKTNAFDFGSSSFGSGFSKALESVGSDTTFKFGTQASPFSSQLGNKSPFSSFTKDDTENGSLSKGSTSEINDDNEEHESNGPNVSGNDLTDSTVEQTSSTRLPETPSDEDGEVVEEEAQKSPIGKLTETIKKSANIDMAGLKNPVFGNHVKAKSESPFSAFATNITKPSSTTPAFSFGNSTMNKSNTSTVSPMEEADTKETSEKGPITLKSVENPFLPAKEERTGESSKKDHNDDPKDGYVSGSEISVRTSESAFDTTANEEIPKSQDVNNHEKSETDPKYSQHAVVDHDNKSKEMNETSKNNERSGQPNHGVQGDGIALKKDNEKENFDSNMAIKQFEDHQSSEEDASEKDSRQSSEVKESDDNMSLNSDRDESISESYDKLEDINTDELPHGGEAFKAREVSASADFDVQTSLEDNYAESGIQTDLSESSKENEVQTDAIPVKHNSTQTVKKEAVDNGLQTEPVETCNFSVQTFEGDENYLAEQCKPKQLKEYYTSAKVSNIPFVSQNSTLRLIESTFQTVEAEFTVLMENIRNMDTFFTDQSSIPLVKRTVRSINNLYTWRIPEAEILLNIQNNIKCEQMQITNANIQDLKEKVTDYVRKDIAQITEDVANAKEEYLFLMHFDDASSGYVKDLSTHQFRMQKTLRQKLFDVSAKINHTEELLNILKLFTVKNKRLDDNPLVAKLAKESLARDGLLKEIKLLREQVSRLQLEEKGKKASSFDASSSITKDMKGFKVVEVGLAMNTKKQIGDFFKNLNMAK
SIO_010081: YIL115C
subclass of: SO_0000673
so part of: YIL115C
location: complement(144327..148709)
location: region:144327-148709:-1
so has part: feature:144327-148709:-1:exon

NP_012151.1
type: Protein
SIO_000068: ncbiprotein

S000001377
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:144327-148709:-1:exon

YIL114C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: POR2
locus tag: YIL114C
so part of: sequence
location: complement(<149143..>149988)
location: region:149143-149988:-1
so has part: feature:149143-149988:-1:exon
subclass of: SO_0000010

854692
type: Gene
SIO_000068: ncbigene

position:149143:-1
position: 149143
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:149988:-1
position: 149988
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:149143-149988:-1:exon

YIL114C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: POR2
locus tag: YIL114C
product: putative porin POR2
transcript id: NM_001179462.3
SIO_010081: YIL114C
subclass of: SO_0000673
so part of: YIL114C
location: complement(<149143..>149988)
location: region:149143-149988:-1
so has part: feature:149143-149988:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:149143-149988:-1:exon

YIL114C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: POR2
locus tag: YIL114C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:11914276|PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005741 mitochondrial outer membrane [PMID:9315631|PMID:16407407]
experiment: EXISTENCE:genetic interaction:GO:0071902 positive regulation of protein serine/threonine kinase activity [PMID:23104570]
experiment: EXISTENCE:mutant phenotype:GO:0045454 cell redox homeostasis [PMID:18768136]
experiment: EXISTENCE:mutant phenotype:GO:0051027 DNA transport [PMID:19056337]
note: Putative mitochondrial porin (voltage-dependent anion channel); not required for mitochondrial membrane permeability or mitochondrial osmotic stability; POR2 has a paralog, POR1, that arose from the whole genome duplication
codon start: 1
product: putative porin POR2
translation: MALRFFNDISRDVNGLFNRDFFHTNPLSLNISTTTENGVNFTLKAKQGVTEGPIQTSVEGRFYDRKEGVSLSQSWSNQNRLNTRIEFSKIAPGWKGDVNAFLTPQSIKNAKFNLSYAQKSFAARTSIDILQPKDFVGSVTLGHRGFVGGTDIAYDTAAGLCARYAMSIGYLAREYSFILSTNNRQCATASFFQNVNRYLQVGTKATLQSKTSSNMNIEFVTRYVPDSISQVKAKIADSGLTTLSYKRNLNKDISLGVGMSFNALQLTEPVHKFGWSLSFSP
SIO_010081: YIL114C
subclass of: SO_0000673
so part of: YIL114C
location: complement(149143..149988)
location: region:149143-149988:-1
so has part: feature:149143-149988:-1:exon

NP_012152.3
type: Protein
SIO_000068: ncbiprotein

S000001376
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:149143-149988:-1:exon

YIL113W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SDP1
locus tag: YIL113W
so part of: sequence
location: <150559..>151188
location: region:150559-151188:1
so has part: feature:150559-151188:1:exon
subclass of: SO_0000010

854693
type: Gene
SIO_000068: ncbigene

position:150559:1
position: 150559
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:151188:1
position: 151188
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:150559-151188:1:exon

YIL113W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SDP1
locus tag: YIL113W
product: mitogen-activated protein kinase tyrosine protein phosphatase SDP1
transcript id: NM_001179461.1
SIO_010081: YIL113W
subclass of: SO_0000673
so part of: YIL113W
location: <150559..>151188
location: region:150559-151188:1
so has part: feature:150559-151188:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:150559-151188:1:exon

YIL113W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SDP1
locus tag: YIL113W
EC number: 3.1.3.48
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:11923319]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11923319]
experiment: EXISTENCE:direct assay:GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity [PMID:12220658]
experiment: EXISTENCE:direct assay:GO:0033550 MAP kinase tyrosine phosphatase activity [PMID:11923319|PMID:17495930]
experiment: EXISTENCE:genetic interaction:GO:0000196 cell wall integrity MAPK cascade [PMID:11923319]
note: Stress-inducible dual-specificity MAP kinase phosphatase; negatively regulates Slt2p MAP kinase by direct dephosphorylation, diffuse localization under normal conditions shifts to punctate localization after heat shock; SDP1 has a paralog, MSG5, that arose from the whole genome duplication
codon start: 1
product: mitogen-activated protein kinase tyrosine protein phosphatase SDP1
translation: MNIYTSPTRTPNIAPKSGQRPSLPMLATDERSTDKESPNEDREFVPCSSLDVRRIYPKGPLLVLPEKIYLYSEPTVKELLPFDVVINVAEEANDLRMQVPAVEYHHYRWEHDSQIALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADKINPSIGLIFQLMEWEVALNAKTNVQANSYRKVP
SIO_010081: YIL113W
subclass of: SO_0000673
so part of: YIL113W
location: 150559..151188
location: region:150559-151188:1
so has part: feature:150559-151188:1:exon

NP_012153.1
type: Protein
SIO_000068: ncbiprotein

S000001375
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:150559-151188:1:exon

YIL112W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HOS4
locus tag: YIL112W
so part of: sequence
location: <151595..>154846
location: region:151595-154846:1
so has part: feature:151595-154846:1:exon
subclass of: SO_0000010

854694
type: Gene
SIO_000068: ncbigene

position:151595:1
position: 151595
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:154846:1
position: 154846
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:151595-154846:1:exon

YIL112W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HOS4
locus tag: YIL112W
product: Hos4p
transcript id: NM_001179460.1
SIO_010081: YIL112W
subclass of: SO_0000673
so part of: YIL112W
location: <151595..>154846
location: region:151595-154846:1
so has part: feature:151595-154846:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:151595-154846:1:exon

YIL112W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: HOS4
locus tag: YIL112W
experiment: EXISTENCE:direct assay:GO:0016575 histone deacetylation [PMID:11711434]
experiment: EXISTENCE:direct assay:GO:0034967 Set3 complex [PMID:11711434]
note: Subunit of the Set3 complex; complex is a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity; potential Cdc28p substrate
codon start: 1
product: Hos4p
translation: MNETTTKQPLKKRSLSSYLSNVSTRREELEKISKQETSEEEDTAGKHEQRETLSEEVSDKFPENVASFRSQTTSVHQATQNNLNAKESEDLAHKNDASSHEGEVNGDSRPDDVPETNEKISQAIRAKISSSSSSPNVRNVDIQNHQPFSRDQLRAMLKEPKRKTVDDFIEEEGLGAVEEEDLSDEVLEKNTTEPENVEKDIEYSDSDKDTDDVGSDDPTAPNSPIKLGRRKLVRGDQLDATTSSMFNNESDSELSDIDDSKNIALSSSLFRGGSSPVKETNNNLSNMNSSPAQNPKRGSVSRSNDSNKSSHIAVSKRPKQKKGIYRDSGGRTRLQIACDKGKYDVVKKMIEEGGYDINDQDNAGNTALHEAALQGHIEIVELLIENGADVNIKSIEMFGDTPLIDASANGHLDVVKYLLKNGADPTIRNAKGLTAFESVDDESEFDDEEDQKILREIKKRLSIAAKKWTNRAGIHNDKSKNGNNAHTIDQPPFDNTTKAKNEKAADSPSMASNIDEKAPEEEFYWTDVTSRAGKEKLFKASKEGHLPYVGTYVENGGKIDLRSFFESVKCGHEDITSIFLAFGFPVNQTSRDNKTSALMVAVGRGHLGTVKLLLEAGADPTKRDKKGRTALYYAKNSIMGITNSEEIQLIENAINNYLKKHSEDNNDDDDDDDNNNETYKHEKKREKTQSPILASRRSATPRIEDEEDDTRMLNLADDDFNNDRDVKESTTSDSRKRLDDNENVGTQYSLDWKKRKTNALQDEEKLKSISPLSMEPHSPKKAKSVEISKIHEETAAEREARLKEEEEYRKKRLEKKRKKEQELLQKLAEDEKKRIEEQEKQKVLEMERLEKATLEKARKMEREKEMEEISYRRAVRDLYPLGLKIINFNDKLDYKRFLPLYYFVDEKNDKFVLDLQVMILLKDIDLLSKDNQPTSEKIPVDPSHLTPLWNMLKFIFLYGGSYDDKKNNMENKRYVVNFDGVDLDTKIGYELLEYKKFVSLPMAWIKWDNVVIENHAKRKEIEGNMIQISINEFARWRNDKLNKAQQPTRKQRSLKIPRELPVKFQHRMSISSVLQQTSKEPFW
SIO_010081: YIL112W
subclass of: SO_0000673
so part of: YIL112W
location: 151595..154846
location: region:151595-154846:1
so has part: feature:151595-154846:1:exon

NP_012154.1
type: Protein
SIO_000068: ncbiprotein

S000001374
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:151595-154846:1:exon

YIL111W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: COX5B
locus tag: YIL111W
so part of: sequence
location: <155222..>155765
location: region:155222-155765:1
so has part: feature:155222-155765:1:exon
subclass of: SO_0000010

854695
type: Gene
SIO_000068: ncbigene

position:155222:1
position: 155222
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:155765:1
position: 155765
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:155222-155765:1:exon

YIL111W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: COX5B
locus tag: YIL111W
product: cytochrome c oxidase subunit Vb
transcript id: NM_001179459.1
SIO_010081: YIL111W
subclass of: SO_0000673
so part of: YIL111W
location: join(<155222,155311..>155765)
location: region:155222-155765:1
so has part: feature:155222-155222:1:exon
so has part: feature:155311-155765:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:155222-155222:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:155311-155765:1:exon

position:155311:1
position: 155311
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YIL111W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: COX5B
locus tag: YIL111W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005751 mitochondrial respiratory chain complex IV [PMID:2986105]
experiment: EXISTENCE:direct assay:GO:0006123 mitochondrial electron transport, cytochrome c to oxygen [PMID:1331058]
experiment: EXISTENCE:mutant phenotype:GO:0004129 cytochrome-c oxidase activity [PMID:2986105]
experiment: EXISTENCE:mutant phenotype:GO:0050421 nitrite reductase (NO-forming) activity [PMID:18388202]
note: Subunit Vb of cytochrome c oxidase; cytochrome c oxidase is the terminal member of the mitochondrial inner membrane electron transport chain; Cox5Bp is predominantly expressed during anaerobic growth while its isoform Va (Cox5Ap) is expressed during aerobic growth; COX5B has a paralog, COX5A, that arose from the whole genome duplication
codon start: 1
product: cytochrome c oxidase subunit Vb
translation: MLRTSLTKGARLTGTRFVQTKALSKATLTDLPERWENMPNLEQKEIADNLTERQKLPWKTLNNEEIKAAWYISYGEWGPRRPVHGKGDVAFITKGVFLGLGISFGLFGLVRLLANPETPKTMNREWQLKSDEYLKSKNANPWGGYSQVQSK
SIO_010081: YIL111W
subclass of: SO_0000673
so part of: YIL111W
location: join(155222,155311..155765)
location: region:155222-155765:1
so has part: feature:155222-155222:1:exon
so has part: feature:155311-155765:1:exon

NP_012155.1
type: Protein
SIO_000068: ncbiprotein

S000001373
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:155222-155222:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:155311-155765:1:exon

YIL110W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MNI1
gene: HPM1
locus tag: YIL110W
gene synonym: MNI1
so part of: sequence
location: <156045..>157178
location: region:156045-157178:1
so has part: feature:156045-157178:1:exon
subclass of: SO_0000010

854696
type: Gene
SIO_000068: ncbigene

position:156045:1
position: 156045
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:157178:1
position: 157178
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:156045-157178:1:exon

YIL110W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MNI1
gene: HPM1
locus tag: YIL110W
gene synonym: MNI1
product: protein-histidine N-methyltransferase
transcript id: NM_001179458.1
SIO_010081: YIL110W
subclass of: SO_0000673
so part of: YIL110W
location: <156045..>157178
location: region:156045-157178:1
so has part: feature:156045-157178:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:156045-157178:1:exon

YIL110W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MNI1
gene: HPM1
locus tag: YIL110W
gene synonym: MNI1
EC number: 2.1.1.85
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0000027 ribosomal large subunit assembly [PMID:24865971|PMID:26826131]
experiment: EXISTENCE:mutant phenotype:GO:0018064 protein-L-histidine N-tele-methyltransferase activity [PMID:20864530]
experiment: EXISTENCE:mutant phenotype:GO:0042038 peptidyl-histidine methylation, to form tele-methylhistidine [PMID:20864530]
experiment: EXISTENCE:mutant phenotype:GO:0045903 positive regulation of translational fidelity [PMID:24865971]
note: AdoMet-dependent methyltransferase; involved in a novel 3-methylhistidine modification of multiple proteins, including ribosomal protein Rpl3p; seven beta-strand MTase family member; null mutant exhibits a weak vacuolar protein sorting defect and caspofungin resistance
codon start: 1
product: protein-histidine N-methyltransferase
translation: MSFSFGFTSNDFDDDELVAQPETFVESSKENENTTAYINPLDSDFLSQAGVVQPNVEDLGTILESLKDVRLTFEEFQSPIYRKPLIKRELFDVKHQLMLETDAQSNNNSTELDILLGDTSEDLRKNIYEGGLKSWECSYDLVDLLSENVDRISNDIDAVVEIGCGTALPSEFLFRSALLRNDRSKGLKFVLTDYNASVLRLVTIPNLVITWAKTVLTKEQWYALQKDECEDIPINNEELLLTSKLLAAFYDDVQSRNISVTLISGSWGRKFSNLIHEVLSGSQKVLSLSSETIYQPDNLPVIAETILDIHNLPQTDVKTYVAAKDIYFGVGGSITEFEAYLDDKINSEHLPIHSERFKVNSGLKRSIICIETNKAIR
SIO_010081: YIL110W
subclass of: SO_0000673
so part of: YIL110W
location: 156045..157178
location: region:156045-157178:1
so has part: feature:156045-157178:1:exon

NP_012156.1
type: Protein
SIO_000068: ncbiprotein

S000001372
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:156045-157178:1:exon

YIL109C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ANU1
gene: SEC24
locus tag: YIL109C
gene synonym: ANU1
so part of: sequence
location: complement(<157385..>160165)
location: region:157385-160165:-1
so has part: feature:157385-160165:-1:exon
subclass of: SO_0000010

854697
type: Gene
SIO_000068: ncbigene

position:157385:-1
position: 157385
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:160165:-1
position: 160165
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:157385-160165:-1:exon

YIL109C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ANU1
gene: SEC24
locus tag: YIL109C
gene synonym: ANU1
product: COPII subunit SEC24
transcript id: NM_001179457.3
SIO_010081: YIL109C
subclass of: SO_0000673
so part of: YIL109C
location: complement(<157385..>160165)
location: region:157385-160165:-1
so has part: feature:157385-160165:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:157385-160165:-1:exon

YIL109C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ANU1
gene: SEC24
locus tag: YIL109C
gene synonym: ANU1
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0030127 COPII vesicle coat [PMID:8004676]
experiment: EXISTENCE:direct assay:GO:0090110 COPII-coated vesicle cargo loading [PMID:12941277|PMID:14627716|PMID:15665868]
experiment: EXISTENCE:mutant phenotype:GO:0005048 signal sequence binding [PMID:12941277]
experiment: EXISTENCE:mutant phenotype:GO:0016236 macroautophagy [PMID:11694599]
note: Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat; required for cargo selection during vesicle formation in ER to Golgi transport; homologous to Sfb3p; SEC24 has a paralog, SFB2, that arose from the whole genome duplication
codon start: 1
product: COPII subunit SEC24
translation: MSHHKKRVYPQAQLQYGQNATPLQQPAQFMPPQDPAAAGMSYGQMGMPPQGAVPSMGQQQFLTPAQEQLHQQIDQATTSMNDMHLHNVPLVDPNAYMQPQVPVQMGTPLQQQQQPMAAPAYGQPSAAMGQNMRPMNQLYPIDLLTELPPPITDLTLPPPPLVIPPERMLVPSELSNASPDYIRSTLNAVPKNSSLLKKSKLPFGLVIRPYQHLYDDIDPPPLNEDGLIVRCRRCRSYMNPFVTFIEQGRRWRCNFCRLANDVPMQMDQSDPNDPKSRYDRNEIKCAVMEYMAPKEYTLRQPPPATYCFLIDVSQSSIKSGLLATTINTLLQNLDSIPNHDERTRISILCVDNAIHYFKIPLDSENNEESADQINMMDIADLEEPFLPRPNSMVVSLKACRQNIETLLTKIPQIFQSNLITNFALGPALKSAYHLIGGVGGKIIVVSGTLPNLGIGKLQRRNESGVVNTSKETAQLLSCQDSFYKNFTIDCSKVQITVDLFLASEDYMDVASLSNLSRFTAGQTHFYPGFSGKNPNDIVKFSTEFAKHISMDFCMETVMRARGSTGLRMSRFYGHFFNRSSDLCAFSTMPRDQSYLFEVNVDESIMADYCYVQVAVLLSLNNSQRRIRIITLAMPTTESLAEVYASADQLAIASFYNSKAVEKALNSSLDDARVLINKSVQDILATYKKEIVVSNTAGGAPLRLCANLRMFPLLMHSLTKHMAFRSGIVPSDHRASALNNLESLPLKYLIKNIYPDVYSLHDMADEAGLPVQTEDGEATGTIVLPQPINATSSLFERYGLYLIDNGNELFLWMGGDAVPALVFDVFGTQDIFDIPIGKQEIPVVENSEFNQRVRNIINQLRNHDDVITYQSLYIVRGASLSEPVNHASAREVATLRLWASSTLVEDKILNNESYREFLQIMKARISK
SIO_010081: YIL109C
subclass of: SO_0000673
so part of: YIL109C
location: complement(157385..160165)
location: region:157385-160165:-1
so has part: feature:157385-160165:-1:exon

NP_012157.3
type: Protein
SIO_000068: ncbiprotein

S000001371
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:157385-160165:-1:exon

YIL108W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YIL108W
so part of: sequence
location: <160887..>162977
location: region:160887-162977:1
so has part: feature:160887-162977:1:exon
subclass of: SO_0000010

854698
type: Gene
SIO_000068: ncbigene

position:160887:1
position: 160887
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:162977:1
position: 162977
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:160887-162977:1:exon

YIL108W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YIL108W
product: putative metalloendopeptidase
transcript id: NM_001179456.1
SIO_010081: YIL108W
subclass of: SO_0000673
so part of: YIL108W
location: <160887..>162977
location: region:160887-162977:1
so has part: feature:160887-162977:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:160887-162977:1:exon

YIL108W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YIL108W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095|PMID:22842922]
note: Putative metalloendopeptidase; forms cytoplasmic foci upon DNA replication stress
codon start: 1
product: putative metalloendopeptidase
translation: MVGSKDIDLFNLRENEQIVSPCLIVHGKCNKQNGAKTVQVQHPQLPPITYPIHNQFFKATVILTPGENKLTFVTDTNTARTIVCYYTPLTQNPPVHLCLILAKDSPLQFDSPREQKDREGGNGLELAIKKLRLGARLMQAYTNEQMLRNSMGNRTFPFVEEFTWDTLFERPAMRNTIKIHVVRSEKTVKEIQDPDIAQQNSKGKNTGALFGIAMDALKSYGGPFTNNEKPVQAACMFLDTHWDGKLIRGHAALGGGDDSIKLAIFGSHGLYSWPTCLEQLVPYFTDETRSSTSEVANDCNECGTYWECLTITLGAFMHEIGHLLGCPHQESGVMLRGYTTLNRSFLTKEAYSVRTNSTGASPPIFPKEECTWNRLDTVRFLYHPSFTLPQDYYDPSFMRPTKLGGYPNIKHSVYPLGNGSCRILSPTGIYLIEIICDDLARGHIEYLPVSLGGQGPQREVIVTLDDLRARLPKNELAKFGNTFKLKILSVNAPETEFDKFPSLLDVQPLDMSKYGFSKNVQGIKSPLYGRSDGGNAVGVVAFDVRLVTAVRIYHGYALDGVRFYYKEKPTGTKDAPASKPSVPPRNYFSKITHSIKNHASINEENLKSVLFGHETQNFTDATLEPGEIIIGFNLRCGAWVDAIQIITSHGRMTDMFGNKDGGGFAELQPPNGQYILGVTGRVGQWVDAFGIIYGAL
SIO_010081: YIL108W
subclass of: SO_0000673
so part of: YIL108W
location: 160887..162977
location: region:160887-162977:1
so has part: feature:160887-162977:1:exon

NP_012158.1
type: Protein
SIO_000068: ncbiprotein

S000001370
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:160887-162977:1:exon

YIL107C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PFK26
locus tag: YIL107C
so part of: sequence
location: complement(<163278..>165761)
location: region:163278-165761:-1
so has part: feature:163278-165761:-1:exon
subclass of: SO_0000010

854699
type: Gene
SIO_000068: ncbigene

position:163278:-1
position: 163278
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:165761:-1
position: 165761
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:163278-165761:-1:exon

YIL107C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PFK26
locus tag: YIL107C
product: 6-phosphofructo-2-kinase
transcript id: NM_001179455.1
SIO_010081: YIL107C
subclass of: SO_0000673
so part of: YIL107C
location: complement(<163278..>165761)
location: region:163278-165761:-1
so has part: feature:163278-165761:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:163278-165761:-1:exon

YIL107C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PFK26
locus tag: YIL107C
EC number: 2.7.1.105
experiment: EXISTENCE:curator inference:GO:0005737 cytoplasm [PMID:1657152]
experiment: EXISTENCE:direct assay:GO:0003873 6-phosphofructo-2-kinase activity [PMID:1322693]
experiment: EXISTENCE:mutant phenotype:GO:0003873 6-phosphofructo-2-kinase activity [PMID:1657152]
experiment: EXISTENCE:mutant phenotype:GO:0006003 fructose 2,6-bisphosphate metabolic process [PMID:1657152]
note: 6-phosphofructo-2-kinase; inhibited by phosphoenolpyruvate and sn-glycerol 3-phosphate; has negligible fructose-2,6-bisphosphatase activity; transcriptional regulation involves protein kinase A
codon start: 1
product: 6-phosphofructo-2-kinase
translation: MFKPVDFSETSPVPPDIDLAPTQSPHHVAPSQDSSYDLLSRSSDDKIDAEKGPHDELSKHLPLFQKRPLSDTPISSNWNSPGITEENTPSDSPENSATNLKSLHRLHINDETQLKNAKIPTNDTTDYMPPSDGANEVTRIDLKDIKSPTRHHKRRPTTIDVPGLTKSKTSPDGLISKEDSGSKLVIVMVGLPATGKSFITNKLSRFLNYSLYYCKVFNVGNTRRKFAKEHGLKDQDSKFFEPKNADSTRLRDKWAMDTLDELLDYLLEGSGSVGIFDATNTSRERRKNVLARIRKRSPHLKVLFLESVCSDHALVQKNIRLKLFGPDYKGKDPESSLKDFKSRLANYLKAYEPIEDDENLQYIKMIDVGKKVIAYNIQGFLASQTVYYLLNFNLADRQIWITRSGESEDNVSGRIGGNSHLTPRGLRFAKSLPKFIARQREIFYQNLMQQKKNNENTDGNIYNDFFVWTSMRARTIGTAQYFNEDDYPIKQMKMLDELSAGDYDGMTYPEIKNNFPEEFEKRQKDKLRYRYPGIGGESYMDVINRLRPVITELERIEDNVLIITHRVVARALLGYFMNLSMGIIANLDVPLHCVYCLEPKPYGITWSLWEYDEASDSFSKVPQTDLNTTRVKEVGLVYNERRYSVIPTAPPSARSSFASDFLSRKRSNPTSASSSQSELSEQPKNSVSAQTGSNNTTLIGSNFNIKNENGDSRIPLSAPLMATNTSNNILDGGGTSISIHRPRVVPNQNNVNPLLANNNKAASNVPNVKKSAATPRQIFEIDKVDEKLSMLKNKSFLLHGKDYPNNADNNDNEDIRAKTMNRSQSHV
SIO_010081: YIL107C
subclass of: SO_0000673
so part of: YIL107C
location: complement(163278..165761)
location: region:163278-165761:-1
so has part: feature:163278-165761:-1:exon

NP_012159.1
type: Protein
SIO_000068: ncbiprotein

S000001369
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:163278-165761:-1:exon

YIL106W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MOB1
locus tag: YIL106W
so part of: sequence
location: <166415..>167444
location: region:166415-167444:1
so has part: feature:166415-167444:1:exon
subclass of: SO_0000010

854700
type: Gene
SIO_000068: ncbigene

position:166415:1
position: 166415
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:167444:1
position: 167444
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:166415-167444:1:exon

YIL106W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MOB1
locus tag: YIL106W
product: Mob1p
transcript id: NM_001179454.1
SIO_010081: YIL106W
subclass of: SO_0000673
so part of: YIL106W
location: join(<166415..166434,166520..>167444)
location: region:166415-167444:1
so has part: feature:166415-166434:1:exon
so has part: feature:166520-167444:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:166415-166434:1:exon

position:166434:1
position: 166434
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:166520-167444:1:exon

position:166520:1
position: 166520
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YIL106W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MOB1
locus tag: YIL106W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005816 spindle pole body [PMID:11434459]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:11434459|PMID:11564880]
experiment: EXISTENCE:direct assay:GO:0019207 kinase regulator activity [PMID:11404483]
experiment: EXISTENCE:direct assay:GO:0034399 nuclear periphery [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0034973 Sid2-Mob1 complex [PMID:9528782]
experiment: EXISTENCE:direct assay:GO:0044732 mitotic spindle pole body [PMID:11564880]
experiment: EXISTENCE:genetic interaction:GO:0007096 regulation of exit from mitosis [PMID:9436989]
experiment: EXISTENCE:mutant phenotype:GO:0000281 mitotic cytokinesis [PMID:11564880]
experiment: EXISTENCE:mutant phenotype:GO:0007096 regulation of exit from mitosis [PMID:9436989]
experiment: EXISTENCE:physical interaction:GO:0034973 Sid2-Mob1 complex [PMID:9528782]
note: Component of the mitotic exit network; associates with and is required for the activation and Cdc15p-dependent phosphorylation of the Dbf2p kinase; required for cytokinesis and cell separation; component of the CCR4 transcriptional complex; relocalizes from cytoplasm to the nuclear periphery upon DNA replication stress
codon start: 1
product: Mob1p
translation: MSFLQNFHISPGQTIRSTRGFKWNTANAANNAGSVSPTKATPHNNTINGNNNNANTINNRADFTNNPVNGYNESDHGRMSPVLTTPKRHAPPPEQLQNVTDFNYTPSHQKPFLQPQAGTTVTTHQDIKQIVEMTLGSEGVLNQAVKLPRGEDENEWLAVHCVDFYNQINMLYGSITEFCSPQTCPRMIATNEYEYLWAFQKGQPPVSVSAPKYVECLMRWCQDQFDDESLFPSKVTGTFPEGFIQRVIQPILRRLFRVYAHIYCHHFNEILELNLQTVLNTSFRHFCLFAQEFELLRPADFGPLLELVMELRDR
SIO_010081: YIL106W
subclass of: SO_0000673
so part of: YIL106W
location: join(166415..166434,166520..167444)
location: region:166415-167444:1
so has part: feature:166415-166434:1:exon
so has part: feature:166520-167444:1:exon

NP_012160.2
type: Protein
SIO_000068: ncbiprotein

S000001368
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:166415-166434:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:166520-167444:1:exon

YIL105C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LIT2
gene: SLM1
locus tag: YIL105C
gene synonym: LIT2
so part of: sequence
location: complement(<167581..>169641)
location: region:167581-169641:-1
so has part: feature:167581-169641:-1:exon
subclass of: SO_0000010

854701
type: Gene
SIO_000068: ncbigene

position:167581:-1
position: 167581
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:169641:-1
position: 169641
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:167581-169641:-1:exon

YIL105C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LIT2
gene: SLM1
locus tag: YIL105C
gene synonym: LIT2
product: phosphatidylinositol 4,5-bisphosphate-binding protein
transcript id: NM_001179453.1
SIO_010081: YIL105C
subclass of: SO_0000673
so part of: YIL105C
location: complement(<167581..>169641)
location: region:167581-169641:-1
so has part: feature:167581-169641:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:167581-169641:-1:exon

YIL105C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LIT2
gene: SLM1
locus tag: YIL105C
gene synonym: LIT2
experiment: EXISTENCE:direct assay:GO:0005546 phosphatidylinositol-4,5-bisphosphate binding [PMID:15689497|PMID:21119626]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:15372071|PMID:15689497|PMID:17101780|PMID:16622836]
experiment: EXISTENCE:direct assay:GO:0032126 eisosome [PMID:19064668|PMID:21451250]
experiment: EXISTENCE:direct assay:GO:0046625 sphingolipid binding [PMID:21119626]
experiment: EXISTENCE:genetic interaction:GO:0001558 regulation of cell growth [PMID:15689497]
experiment: EXISTENCE:genetic interaction:GO:0016197 endosomal transport [PMID:21451250]
experiment: EXISTENCE:genetic interaction:GO:0030036 actin cytoskeleton organization [PMID:15372071|PMID:15689497]
experiment: EXISTENCE:genetic interaction:GO:0051017 actin filament bundle assembly [PMID:15689497]
experiment: EXISTENCE:genetic interaction:GO:0070941 eisosome assembly [PMID:21451250]
experiment: EXISTENCE:genetic interaction:GO:0072659 protein localization to plasma membrane [PMID:22307609]
experiment: EXISTENCE:physical interaction:GO:0001558 regulation of cell growth [PMID:15689497]
experiment: EXISTENCE:physical interaction:GO:0030950 establishment or maintenance of actin cytoskeleton polarity [PMID:15689497]
experiment: EXISTENCE:physical interaction:GO:0031929 TOR signaling [PMID:15689497]
note: Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p; acts downstream of Mss4p in a pathway regulating actin cytoskeleton organization in response to stress; TORC2 complex substrate and effector; protein abundance increases in response to DNA replication stress; SLM1 has a paralog, SLM2, that arose from the whole genome duplication
codon start: 1
product: phosphatidylinositol 4,5-bisphosphate-binding protein
translation: MSKNNTMTSAVSDMLSQQQLNLQHLHNLQQHTRSMTSADHANVLQQQQQQQQQQQQQQQQQQQSASFQNGSLTSDINQQSYLNGQPVPSTSNSTFQNNRTLTMNSGGLQGIISNGSPNIDSNTNVTIAVPDPNNNNGKQLQGKNSLTNTSILSRARSSLQRQRLAQQQQQQQDPRSPLVILVPTAAQPTDILAARFSAWRNVIKSVIVYLTEIASIQDEIVRQQLRLSHAVQFPFFSIENQYQPSSQEDKSVQKFFLPLGNGSIQDLPTILNQYHESLASSASKASRELTNDVIPRLEDLRRDLIVKIKEIKSLQSDFKNSCSKELQQTKQAMKQFQESLKDARYSVPKQDPFLTKLALDRQIKKQLQEENFLHEAFDNLETSGAELEKIVVMEIQNSLTIYARLLGQEAQLVFDILISKLDSGFFNVDPQFEWDNFISRDPNFLLPNLPMRTFKEIVYKYQFDPLTYEIKSGFLERRSKFLKSYSKGYYVLTPNFLHEFKTADRKKDLVPVMSLALSECTVTEHSRKNSTSSPNSTGSDAKFVLHAKQNGIIRRGHNWVFKADSYESMMSWFDNLKILTSTSNIQDKYKFITQKLNLNSDGKPKLTNNHTSINKYQLSNANSTMVENDENDDINSNYVGSTVTPKLDNQTNTNTSMSSLPDTNDSELQDQVPNIYIQTPINDFKS
SIO_010081: YIL105C
subclass of: SO_0000673
so part of: YIL105C
location: complement(167581..169641)
location: region:167581-169641:-1
so has part: feature:167581-169641:-1:exon

NP_012161.1
type: Protein
SIO_000068: ncbiprotein

S000001367
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:167581-169641:-1:exon

YIL105W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YIL105W-A
so part of: sequence
location: <167664..>167804
location: region:167664-167804:1
so has part: feature:167664-167804:1:exon
subclass of: SO_0000010

13393613
type: Gene
SIO_000068: ncbigene

position:167664:1
position: 167664
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:167804:1
position: 167804
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:167664-167804:1:exon

YIL105W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YIL105W-A
product: uncharacterized protein
transcript id: NM_001270750.1
SIO_010081: YIL105W-A
subclass of: SO_0000673
so part of: YIL105W-A
location: <167664..>167804
location: region:167664-167804:1
so has part: feature:167664-167804:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:167664-167804:1:exon

YIL105W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YIL105W-A
note: hypothetical protein; completely overlaps the verified gene SLM1; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching; mRNA identified as translated by ribosome profiling data
codon start: 1
product: uncharacterized protein
translation: MKTWMYSYLFDCPILVLPWTPHNYYLYHRFHHFLPLCYWHYSADTY
SIO_010081: YIL105W-A
subclass of: SO_0000673
so part of: YIL105W-A
location: 167664..167804
location: region:167664-167804:1
so has part: feature:167664-167804:1:exon

NP_001257679.1
type: Protein
SIO_000068: ncbiprotein

S000028657
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:167664-167804:1:exon

YIL104C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SHQ1
locus tag: YIL104C
so part of: sequence
location: complement(<169982..>171505)
location: region:169982-171505:-1
so has part: feature:169982-171505:-1:exon
subclass of: SO_0000010

854702
type: Gene
SIO_000068: ncbigene

position:169982:-1
position: 169982
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:171505:-1
position: 171505
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:169982-171505:-1:exon

YIL104C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SHQ1
locus tag: YIL104C
product: Hsp90 cochaperone SHQ1
transcript id: NM_001179452.3
SIO_010081: YIL104C
subclass of: SO_0000673
so part of: YIL104C
location: complement(<169982..>171505)
location: region:169982-171505:-1
so has part: feature:169982-171505:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:169982-171505:-1:exon

YIL104C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SHQ1
locus tag: YIL104C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0005654 nucleoplasm [PMID:12228251]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0051082 unfolded protein binding [PMID:19426738]
experiment: EXISTENCE:mutant phenotype:GO:0000493 box H/ACA snoRNP assembly [PMID:12228251]
experiment: EXISTENCE:physical interaction:GO:0000493 box H/ACA snoRNP assembly [PMID:12228251]
note: Chaperone protein; required for the assembly of box H/ACA snoRNPs and thus for pre-rRNA processing; functions as an RNA mimic; forms a complex with Naf1p and interacts with H/ACA snoRNP components Nhp2p and Cbf5p; homology with known Hsp90p cochaperones; relocalizes to the cytosol in response to hypoxia
codon start: 1
product: Hsp90 cochaperone SHQ1
translation: MITPRFSITQDEEFIFLKIFISNIRFSAVGLEIIIQENMIIFHLSPYYLRLRFPHELIDDERSTAQYDSKDECINVKVAKLNKNEYFEDLDLPTKLLARQGDLAGADALTENTDAKKTQKPLIQEVETDGVSNNIKDDVKTIGQMGEGFNWEIEQKMDSSTNNGILKTKYGFDNLYDTVISVSTSNGNDINELDDPEHTDANDRVIERLRKENLKFDPEYYVSEYMTHKYGNEEDLEINGIKELLKFTPSIVKQYLQWYKDSTNPNLVMPIEFTDEEQKQMQDNLPKKSYLVEDIKPLYVTILSVLFSYVFEQIENEGTHTTESAWTMGKLCPQISFLDQQLKQVNELQDGMKEISKVNKDSSLIKIAIITGIRRALSYPLHRNYDLAMKAWTFVYYILRGGKRLVIRALLDIHETFRFHDVYYVYDKVLLDDLTAWFISQGSENVIRSLALEMRKEQESLSKQDIEFECIASFNEQTGEPEWETLNIREMEILAESEYREQQQNPQ
SIO_010081: YIL104C
subclass of: SO_0000673
so part of: YIL104C
location: complement(169982..171505)
location: region:169982-171505:-1
so has part: feature:169982-171505:-1:exon

NP_012162.3
type: Protein
SIO_000068: ncbiprotein

S000001366
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:169982-171505:-1:exon

YIL103W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: DPH1
locus tag: YIL103W
so part of: sequence
location: <171751..>173028
location: region:171751-173028:1
so has part: feature:171751-173028:1:exon
subclass of: SO_0000010

854703
type: Gene
SIO_000068: ncbigene

position:171751:1
position: 171751
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:173028:1
position: 173028
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:171751-173028:1:exon

YIL103W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: DPH1
locus tag: YIL103W
product: 2-(3-amino-3-carboxypropyl)histidine synthase
transcript id: NM_001179451.1
SIO_010081: YIL103W
subclass of: SO_0000673
so part of: YIL103W
location: <171751..>173028
location: region:171751-173028:1
so has part: feature:171751-173028:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:171751-173028:1:exon

YIL103W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: DPH1
locus tag: YIL103W
EC number: 2.5.1.108
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095|PMID:11914276]
experiment: EXISTENCE:mutant phenotype:GO:0017183 peptidyl-diphthamide biosynthetic process from peptidyl-histidine [PMID:15485916]
note: Protein required for synthesis of diphthamide; required along with Dph2p, Kti11p, Jjj3p, and Dph5p; diphthamide is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); forms a complex with Dph2p that catalyzes the first step of diphthamide biosynthesis
codon start: 1
product: 2-(3-amino-3-carboxypropyl)histidine synthase
translation: MSGSTESKKQPRRRFIGRKSGNSNNDKLTTVAENGNEIIHKQKSRIALGRSVNHVPEDILNDKELNEAIKLLPSNYNFEIHKTVWNIRKYNAKRIALQMPEGLLIYSLIISDILEQFCGVETLVMGDVSYGACCIDDFTARALDCDFIVHYAHSCLVPIDVTKIKVLYVFVTINIQEDHIIKTLQKNFPKGSRIATFGTIQFNPAVHSVRDKLLNDEEHMLYIIPPQIKPLSRGEVLGCTSERLDKEQYDAMVFIGDGRFHLESAMIHNPEIPAFKYDPYNRKFTREGYDQKQLVEVRAEAIEVARKGKVFGLILGALGRQGNLNTVKNLEKNLIAAGKTVVKIILSEVFPQKLAMFDQIDVFVQVACPRLSIDWGYAFNKPLLTPYEASVLLKKDVMFSEKYYPMDYYEAKGYGRGETPKHAIE
SIO_010081: YIL103W
subclass of: SO_0000673
so part of: YIL103W
location: 171751..173028
location: region:171751-173028:1
so has part: feature:171751-173028:1:exon

NP_012163.1
type: Protein
SIO_000068: ncbiprotein

S000001365
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:171751-173028:1:exon

YIL102C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YIL102C-A
so part of: sequence
location: complement(<173365..>173592)
location: region:173365-173592:-1
so has part: feature:173365-173592:-1:exon
subclass of: SO_0000010

3799974
type: Gene
SIO_000068: ncbigene

position:173365:-1
position: 173365
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:173592:-1
position: 173592
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:173365-173592:-1:exon

YIL102C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YIL102C-A
product: uncharacterized protein
transcript id: NM_001184686.1
SIO_010081: YIL102C-A
subclass of: SO_0000673
so part of: YIL102C-A
location: complement(<173365..>173592)
location: region:173365-173592:-1
so has part: feature:173365-173592:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:173365-173592:-1:exon

YIL102C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YIL102C-A
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
note: Regulatory subunit of dolichyl phosphate mannose (DPM) synthase; identified based on comparisons of the genome sequences of six Saccharomyces species; SWAT-GFP, seamless-GFP and mCherry fusion proteins localize to the endoplasmic reticulum
codon start: 1
product: uncharacterized protein
translation: MNRFVIICLLFTYYVIWSLLPIFEIENSNPVVSLLFPISSNVAIFLPIFLLLIGFTLTGSVLGVLLIRSDKKKKV
SIO_010081: YIL102C-A
subclass of: SO_0000673
so part of: YIL102C-A
location: complement(173365..173592)
location: region:173365-173592:-1
so has part: feature:173365-173592:-1:exon

NP_001032579.1
type: Protein
SIO_000068: ncbiprotein

S000113587
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:173365-173592:-1:exon

YIL102C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YIL102C
so part of: sequence
location: complement(<174582..>174887)
location: region:174582-174887:-1
so has part: feature:174582-174887:-1:exon
subclass of: SO_0000010

854704
type: Gene
SIO_000068: ncbigene

position:174582:-1
position: 174582
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:174887:-1
position: 174887
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:174582-174887:-1:exon

YIL102C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YIL102C
product: uncharacterized protein
transcript id: NM_001179450.1
SIO_010081: YIL102C
subclass of: SO_0000673
so part of: YIL102C
location: complement(<174582..>174887)
location: region:174582-174887:-1
so has part: feature:174582-174887:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:174582-174887:-1:exon

YIL102C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YIL102C
codon start: 1
product: uncharacterized protein
translation: MLKVEKFKKLKRFEVYYCLKNSFLEEVDIEMKYSCSITTIMSNGSASLLMNWEELTPGHCFTSYTTNPIAGDYGLNASAIDGHTEELVATHPAGTLENATQ
SIO_010081: YIL102C
subclass of: SO_0000673
so part of: YIL102C
location: complement(174582..174887)
location: region:174582-174887:-1
so has part: feature:174582-174887:-1:exon

NP_012164.1
type: Protein
SIO_000068: ncbiprotein

S000001364
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:174582-174887:-1:exon

YNCI0002W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCI0002W
so part of: sequence
location: 175031..175103
location: region:175031-175103:1
so has part: feature:175031-175103:1:exon
subclass of: SO_0000663

854705
type: Gene
SIO_000068: ncbigene

position:175031:1
position: 175031
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:175103:1
position: 175103
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:175031-175103:1:exon

YNCI0002W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCI0002W
product: tRNA-Thr
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Threonine tRNA (tRNA-Thr), predicted by tRNAscan-SE analysis
SIO_010081: YNCI0002W
subclass of: SO_0000673
so part of: YNCI0002W
location: 175031..175103
location: region:175031-175103:1
so has part: feature:175031-175103:1:exon

S000006741
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:175031-175103:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS912; Autonomously Replicating Sequence
so part of: sequence
location: 175038..175358
location: region:175038-175358:1
so has part: feature:175038-175358:1:region

S000118396
type: SGD
SIO_000068: sgd

position:175038:1
position: 175038
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:175358:1
position: 175358
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:175038-175358:1:region

YIL101C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: XBP1
locus tag: YIL101C
so part of: sequence
location: complement(<175307..>177250)
location: region:175307-177250:-1
so has part: feature:175307-177250:-1:exon
subclass of: SO_0000010

854706
type: Gene
SIO_000068: ncbigene

position:175307:-1
position: 175307
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:177250:-1
position: 177250
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:175307-177250:-1:exon

YIL101C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: XBP1
locus tag: YIL101C
product: Xbp1p
transcript id: NM_001179449.1
SIO_010081: YIL101C
subclass of: SO_0000673
so part of: YIL101C
location: complement(<175307..>177250)
location: region:175307-177250:-1
so has part: feature:175307-177250:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:175307-177250:-1:exon

YIL101C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: XBP1
locus tag: YIL101C
experiment: EXISTENCE:direct assay:GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific [PMID:10611226]
experiment: EXISTENCE:direct assay:GO:0003700 DNA-binding transcription factor activity [PMID:9343412]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:9343412|PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:19158363]
experiment: EXISTENCE:mutant phenotype:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:10611226|PMID:11340165|PMID:24204289|PMID:9343412]
note: Transcriptional repressor; binds promoter sequences of cyclin genes, CYS3, and SMF2; not expressed during log phase of growth, but induced by stress or starvation during mitosis, and late in meiosis; represses 15% of all yeast genes as cells transition to quiescence; important for maintaining G1 arrest and for longevity of quiescent cells; member of Swi4p/Mbp1p family; phosphorylated by Cdc28p; relative distribution to nucleus increases upon DNA replication stress
codon start: 1
product: Xbp1p
translation: MKYPAFSINSDTVHLTDNPLDDYQRLYLVSVLDRDSPPASFSAGLNIRKVNYKSSIAAQFTHPNFIISARDAGNGEEAAAQNVLNCFEYQFPNLQTIQSLVHEQTLLSQLASSATPHSALHLHDKNILMGKIILPSRSNKTPVSASPTKQEKKALSTASRENATSSLTKNQQFKLTKMDHNLINDKLINPNNCVIWSHDSGYVFMTGIWRLYQDVMKGLINLPRGDSVSTSQQQFFCKAEFEKILSFCFYNHSSFTSEESSSVLLSSSTSSPPKRRTSTGSTFLDANASSSSTSSTQANNYIDFHWNNIKPELRDLICQSYKDFLINELGPDQIDLPNLNPANFTKRIRGGYIKIQGTWLPMEISRLLCLRFCFPIRYFLVPIFGPDFPKDCESWYLAHQNVTFASSTTGAGAATAATAAANTSTNFTSTAVARPRQKPRPRPRQRSTSMSHSKAQKLVIEDALPSFDSFVENLGLSSNDKNFIKKNSKRQKSSTYTSQTSSPIGPRDPTVQILSNLASFYNTHGHRYSYPGNIYIPQQRYSLPPPNQLSSPQRQLNYTYDHIHPVPSQYQSPRHYNVPSSPIAPAPPTFPQPYGDDHYHFLKYASEVYKQQNQRPAHNTNTNMDTSFSPRANNSLNNFKFKTNSKQ
SIO_010081: YIL101C
subclass of: SO_0000673
so part of: YIL101C
location: complement(175307..177250)
location: region:175307-177250:-1
so has part: feature:175307-177250:-1:exon

NP_012165.1
type: Protein
SIO_000068: ncbiprotein

S000001363
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:175307-177250:-1:exon

YIL099W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SGA1
locus tag: YIL099W
so part of: sequence
location: <178004..>179653
location: region:178004-179653:1
so has part: feature:178004-179653:1:exon
subclass of: SO_0000010

854708
type: Gene
SIO_000068: ncbigene

position:178004:1
position: 178004
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:179653:1
position: 179653
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:178004-179653:1:exon

YIL099W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SGA1
locus tag: YIL099W
product: glucan 1,4-alpha-glucosidase
transcript id: NM_001179447.3
SIO_010081: YIL099W
subclass of: SO_0000673
so part of: YIL099W
location: <178004..>179653
location: region:178004-179653:1
so has part: feature:178004-179653:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:178004-179653:1:exon

YIL099W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SGA1
locus tag: YIL099W
EC number: 3.2.1.3
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:2493265|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0004339 glucan 1,4-alpha-glucosidase activity [PMID:2493265]
experiment: EXISTENCE:direct assay:GO:0005628 prospore membrane [PMID:24390141]
experiment: EXISTENCE:mutant phenotype:GO:0005980 glycogen catabolic process [PMID:11486014]
note: Intracellular sporulation-specific glucoamylase; involved in glycogen degradation; induced during starvation of a/a diploids late in sporulation, but dispensable for sporulation
codon start: 1
product: glucan 1,4-alpha-glucosidase
translation: MARQKMFYNKLLGMLSVGFGFAWALENITIYEFDFGKGILDQSYGGVFSNNGPSQVQLRDAVLMNGTVVYDSNGAWDSSALEEWLQGQKKVSIEKIFENIGPSAVYPSISPGVVIASPSQTHPDYFYQWIRDSALTINSIVSHSAGPAIETLLQYLNVSFHLQRSNNTLGAGIGYTNDTVALGDPKWNVDNTAFTEDWGRPQNDGPALRSIAILKIIDYIKQSGTDLGAKYPFQSTADIFDDIVRWDLRFIIDHWNSSGFDLWEEVNGMHFFTLLVQLSAVDKSLSYFNASERSSPFVEELRQTRRDISKFLVDPANGFINGKYNYIVGTPMIADTLRSGLDISTLLAANTVHDAPSASHLPFDINDPAVLNTLHHLMLHMRSIYPINDSSKNATGIALGRYPEDVYDGYGFGEGNPWVLATCTASTTLYQLIYRHISEQHDLVVPMNNDCSNAFWSELVFSNLTTLGNDEGYLILEFNTPAFNQTIQKIFQLADSFLVKLKAHVGTDGELSEQFNKYTGFMQGAQHLTWSYTSFWDAYQIRQEVLQSL
SIO_010081: YIL099W
subclass of: SO_0000673
so part of: YIL099W
location: 178004..179653
location: region:178004-179653:1
so has part: feature:178004-179653:1:exon

NP_012167.3
type: Protein
SIO_000068: ncbiprotein

S000001361
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:178004-179653:1:exon

YIL098C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FMC1
locus tag: YIL098C
so part of: sequence
location: complement(<179772..>180239)
location: region:179772-180239:-1
so has part: feature:179772-180239:-1:exon
subclass of: SO_0000010

854709
type: Gene
SIO_000068: ncbigene

position:179772:-1
position: 179772
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:180239:-1
position: 180239
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:179772-180239:-1:exon

YIL098C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FMC1
locus tag: YIL098C
product: Fmc1p
transcript id: NM_001179446.3
SIO_010081: YIL098C
subclass of: SO_0000673
so part of: YIL098C
location: complement(<179772..>180239)
location: region:179772-180239:-1
so has part: feature:179772-180239:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:179772-180239:-1:exon

YIL098C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FMC1
locus tag: YIL098C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005759 mitochondrial matrix [PMID:11096112]
experiment: EXISTENCE:genetic interaction:GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly [PMID:11096112]
experiment: EXISTENCE:mutant phenotype:GO:0016236 macroautophagy [PMID:19793921]
experiment: EXISTENCE:mutant phenotype:GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly [PMID:11096112]
note: Mitochondrial matrix protein; required for assembly or stability at high temperature of the F1 sector of mitochondrial F1F0 ATP synthase; null mutant temperature sensitive growth on glycerol is suppressed by multicopy expression of Odc1p
codon start: 1
product: Fmc1p
translation: MDRPRTLRTYRGLIRAILKYERPSKIVNWGNLRKAMITKLEYAKKQNQRDSHENINRQLEKWKKLDPVSDRSLNLFIADSKSLRSILQNDIKWEKKVAQGQNVDEIFEHALDIIKFLDNQREYEELVDRYNPGNKLTQDEKVKRTANVVGLDVPT
SIO_010081: YIL098C
subclass of: SO_0000673
so part of: YIL098C
location: complement(179772..180239)
location: region:179772-180239:-1
so has part: feature:179772-180239:-1:exon

NP_012168.3
type: Protein
SIO_000068: ncbiprotein

S000001360
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:179772-180239:-1:exon

YIL097W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: GID9
gene: FYV10
locus tag: YIL097W
gene synonym: GID9
so part of: sequence
location: <180427..>181977
location: region:180427-181977:1
so has part: feature:180427-181977:1:exon
subclass of: SO_0000010

854710
type: Gene
SIO_000068: ncbigene

position:180427:1
position: 180427
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:181977:1
position: 181977
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:180427-181977:1:exon

YIL097W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: GID9
gene: FYV10
locus tag: YIL097W
gene synonym: GID9
product: glucose-induced degradation complex subunit FYV10
transcript id: NM_001179445.1
SIO_010081: YIL097W
subclass of: SO_0000673
so part of: YIL097W
location: <180427..>181977
location: region:180427-181977:1
so has part: feature:180427-181977:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:180427-181977:1:exon

YIL097W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: GID9
gene: FYV10
locus tag: YIL097W
gene synonym: GID9
EC number: 2.3.2.27
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0034657 GID complex [PMID:16872538|PMID:18508925]
experiment: EXISTENCE:mutant phenotype:GO:0043066 negative regulation of apoptotic process [PMID:18355271]
experiment: EXISTENCE:mutant phenotype:GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process [PMID:12686616]
experiment: EXISTENCE:mutant phenotype:GO:0045721 negative regulation of gluconeogenesis [PMID:12686616]
experiment: EXISTENCE:mutant phenotype:GO:0061630 ubiquitin protein ligase activity [PMID:22044534]
note: Subunit of GID complex; involved in proteasome-dependent catabolite inactivation of gluconeogenic enzymes FBPase, PEPCK, and c-MDH; forms dimer with Rmd5p that is then recruited to GID Complex by Gid8p; contains a degenerate RING finger motif needed for GID complex ubiquitin ligase activity in vivo, as well as CTLH and CRA domains; plays role in anti-apoptosis; required for survival upon exposure to K1 killer toxin
codon start: 1
product: glucose-induced degradation complex subunit FYV10
translation: MAEKSIFNEPDVDFHLKLNQQLFHIPYELLSKRIKHTQAVINKETKSLHEHTAALNQIFEHNDVEHDELALAKITEMIRKVDHIERFLNTQIKSYCQILNRIKKRLEFFHELKDIKSQNSGTSHNGNNEGTRTKLIQWYQSYTNILIGDYLTRNNPIKYNSETKDHWNSGVVFLKQSQLDDLIDYDVLLEANRISTSLLHERNLLPLISWINENKKTLTKKSSILEFQARLQEYIELLKVDNYTDAIVCFQRFLLPFVKSNFTDLKLASGLLIFIKYCNDQKPTSSTSSGFDTEEIKSQSLPMKKDRIFQHFFHKSLPRITSKPAVNTTDYDKSSLINLQSGDFERYLNLLDDQRWSVLNDLFLSDFYSMYGISQNDPLLIYLSLGISSLKTRDCLHPSDDENGNQETETATTAEKEVEDLQLFTLHSLKRKNCPVCSETFKPITQALPFAHHIQSQLFENPILLPNGNVYDSKKLKKLAKTLKKQNLISLNPGQIMDPVDMKIFCESDSIKMYPT
SIO_010081: YIL097W
subclass of: SO_0000673
so part of: YIL097W
location: 180427..181977
location: region:180427-181977:1
so has part: feature:180427-181977:1:exon

NP_012169.1
type: Protein
SIO_000068: ncbiprotein

S000001359
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:180427-181977:1:exon

YIL096C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: BMT5
locus tag: YIL096C
so part of: sequence
location: complement(<182117..>183127)
location: region:182117-183127:-1
so has part: feature:182117-183127:-1:exon
subclass of: SO_0000010

854711
type: Gene
SIO_000068: ncbigene

position:182117:-1
position: 182117
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:183127:-1
position: 183127
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:182117-183127:-1:exon

YIL096C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: BMT5
locus tag: YIL096C
product: 25S rRNA (uracil2634-N3)-methyltransferase
transcript id: NM_001179444.1
SIO_010081: YIL096C
subclass of: SO_0000673
so part of: YIL096C
location: complement(<182117..>183127)
location: region:182117-183127:-1
so has part: feature:182117-183127:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:182117-183127:-1:exon

YIL096C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: BMT5
locus tag: YIL096C
EC number: 2.1.1.313
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:24335083|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0008757 S-adenosylmethionine-dependent methyltransferase activity [PMID:21858014]
experiment: EXISTENCE:mutant phenotype:GO:0070042 rRNA (uridine-N3-)-methyltransferase activity [PMID:24335083]
experiment: EXISTENCE:mutant phenotype:GO:0070475 rRNA base methylation [PMID:24335083]
note: Methyltransferase required for m3U2634 methylation of the 25S rRNA; S-adenosylmethionine-dependent; associates with precursors of the 60S ribosomal subunit; predicted to be involved in ribosome biogenesis
codon start: 1
product: 25S rRNA (uracil2634-N3)-methyltransferase
translation: MARKLKGKIGSKGLKGALLRHKAKVKLVRNIESKQKHELRKKNSSANNKTVKRNQEFQKLNQGKVMPFEKDETLMLCGEGDFSFARSIVEQNYIESDNLIITSYDNSVNELKLKYPHTFEENYQYLKDLNIPIFFQIDVTKLVKSFKISKNNTWFKIINRLSDHRWGNKPLQNIVFNFPHNGKGIKDQERNIREHQDLIFNFFQNSLQLFNLINTKIQNDTLRYTQGYDLNEDTPQAKKLTAEGYGNIILSLFDGEPYDSWQIKLLAKKNGLTLSRSSKFQWENFPGYHHRRTNSEQDTTKPAKERDARFYIFSKYVSNSSKHNRKSKKDTDSDSD
SIO_010081: YIL096C
subclass of: SO_0000673
so part of: YIL096C
location: complement(182117..183127)
location: region:182117-183127:-1
so has part: feature:182117-183127:-1:exon

NP_012170.1
type: Protein
SIO_000068: ncbiprotein

S000001358
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:182117-183127:-1:exon

YNCI0003C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCI0003C
so part of: sequence
location: complement(183440..183513)
location: region:183440-183513:-1
so has part: feature:183440-183513:-1:exon
subclass of: SO_0000663

854712
type: Gene
SIO_000068: ncbigene

position:183440:-1
position: 183440
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:183513:-1
position: 183513
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:183440-183513:-1:exon

YNCI0003C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCI0003C
product: tRNA-Ile
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Isoleucine tRNA (tRNA-Ile), predicted by tRNAscan-SE analysis
SIO_010081: YNCI0003C
subclass of: SO_0000673
so part of: YNCI0003C
location: complement(183440..183513)
location: region:183440-183513:-1
so has part: feature:183440-183513:-1:exon

S000006605
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:183440-183513:-1:exon

YIL095W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PAK1
gene: PRK1
locus tag: YIL095W
gene synonym: PAK1
so part of: sequence
location: <183937..>186369
location: region:183937-186369:1
so has part: feature:183937-186369:1:exon
subclass of: SO_0000010

854713
type: Gene
SIO_000068: ncbigene

position:183937:1
position: 183937
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:186369:1
position: 186369
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:183937-186369:1:exon

YIL095W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PAK1
gene: PRK1
locus tag: YIL095W
gene synonym: PAK1
product: serine/threonine protein kinase PRK1
transcript id: NM_001179443.1
SIO_010081: YIL095W
subclass of: SO_0000673
so part of: YIL095W
location: <183937..>186369
location: region:183937-186369:1
so has part: feature:183937-186369:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:183937-186369:1:exon

YIL095W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PAK1
gene: PRK1
locus tag: YIL095W
gene synonym: PAK1
EC number: 2.7.11.1
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:16319894]
experiment: EXISTENCE:direct assay:GO:0004674 protein serine/threonine kinase activity [PMID:17978096|PMID:9885245|PMID:11739778|PMID:13679512|PM ID:12956961]
experiment: EXISTENCE:direct assay:GO:0030479 actin cortical patch [PMID:10087264|PMID:9885245]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:19053807]
experiment: EXISTENCE:genetic interaction:GO:0120133 negative regulation of actin cortical patch assembly [PMID:9885245]
experiment: EXISTENCE:genetic interaction:GO:1900186 negative regulation of clathrin-dependent endocytosis [PMID:13679512]
experiment: EXISTENCE:mutant phenotype:GO:0000147 actin cortical patch assembly [PMID:12952930]
experiment: EXISTENCE:mutant phenotype:GO:0031333 negative regulation of protein-containing complex assembly [PMID:11739778]
experiment: EXISTENCE:mutant phenotype:GO:1900186 negative regulation of clathrin-dependent endocytosis [PMID:12956961]
note: Ser/Thr protein kinase; regulates the organization and function of the actin cytoskeleton; inhibits clathrin-mediated endocytosis; phosphorylates the Pan1p and Sla1p subunits of the Pan1p-Sla1p-End3p complex, resulting in inhibition of complex formation; inhibits Scd5p through phosphorylation; phosphorylates Pan1p-interacting proteins, Ent1/2 and Yap1801/2; negatively regulated through autophosphorylation; functional overlap with ARK1
codon start: 1
product: serine/threonine protein kinase PRK1
translation: MNTPQISLYEPGTILTVGSHHAKIIKYLTSGGFAQVYTAEISPPDPYSNANIACLKRVIVPHKQGLNTLRAEVDAMKLLRNNKHVVSYIDSHAARSVNGIAYEVFVLMEFCERGGLIDFMNTRLQNRLQESEILEIMSQTVQGITAMHALQPPLIHRDIKIENVLISHDGLYKVCDFGSVSGVIRPPRNTQEFNYVQHDILTNTTAQYRSPEMIDLYRGLPIDEKSDIWALGVFLYKICYYTTPFEKSGEAGILHARYQYPSFPQYSDRLKNLIRLMLMEAPSQRPNICQVLEEVSRLQNKPCPIRNFYLLRAMNQNANTQLAGEPSSTTYVPTQKFIPVQSLQSINQPPNMMPVTHVSTTPNLGTFPISINDNNKTEVTAHAGLQVGSHSNLTSPLMKTKSVPLSDEFASLYYKELHPFQKSQTFKSVESFQSPQRKSMPPLSLTPVNNDIFDRVSAINRPNNYVDSETQTIDNMAVPNLKLSPTITSKSLSSTKEIAAPDNINGSKIVRSLSSKLKKVITGESRGNSPIKSRQNTGDSIRSAFGKLRHGFTGNSVNNSRSASFDNNNVNGNGNNTNRRLVSSSTSSFPKFNSDTKRKEESDKNQRLEKRRSMPPSILSDFDQHERNNSRTGSRDYYRSHSPVKKTQASAKTTSKPTLIPDNGNVNINQEKKESIQRRVHNLLKSSDDPVTYKSASGYGKYTDIGTETSNRHSSVRITPITEEKFKKTLKDGVLDIKTKSNGKDKSRPPRPPPKPLHLRTEIQKIRNFSRLQSKKLPIERISSEATETIVDVNVDDLEADFRKRFPSKV
SIO_010081: YIL095W
subclass of: SO_0000673
so part of: YIL095W
location: 183937..186369
location: region:183937-186369:1
so has part: feature:183937-186369:1:exon

NP_012171.1
type: Protein
SIO_000068: ncbiprotein

S000001357
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:183937-186369:1:exon

YIL094C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LYS10
alternative label: LYS11
gene: LYS12
locus tag: YIL094C
gene synonym: LYS10; LYS11
so part of: sequence
location: complement(<186517..>187632)
location: region:186517-187632:-1
so has part: feature:186517-187632:-1:exon
subclass of: SO_0000010

854714
type: Gene
SIO_000068: ncbigene

position:186517:-1
position: 186517
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:187632:-1
position: 187632
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:186517-187632:-1:exon

YIL094C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LYS10
alternative label: LYS11
gene: LYS12
locus tag: YIL094C
gene synonym: LYS10; LYS11
product: homoisocitrate dehydrogenase
transcript id: NM_001179442.1
SIO_010081: YIL094C
subclass of: SO_0000673
so part of: YIL094C
location: complement(<186517..>187632)
location: region:186517-187632:-1
so has part: feature:186517-187632:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:186517-187632:-1:exon

YIL094C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LYS10
alternative label: LYS11
gene: LYS12
locus tag: YIL094C
gene synonym: LYS10; LYS11
EC number: 1.1.1.87
experiment: EXISTENCE:curator inference:GO:0009085 lysine biosynthetic process [PMID:17223711]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:11914276|PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0047046 homoisocitrate dehydrogenase activity [PMID:17223711]
note: Homo-isocitrate dehydrogenase; an NAD-linked mitochondrial enzyme required for the fourth step in the biosynthesis of lysine, in which homo-isocitrate is oxidatively decarboxylated to alpha-ketoadipate
codon start: 1
product: homoisocitrate dehydrogenase
translation: MFRSVATRLSACRGLASNAARKSLTIGLIPGDGIGKEVIPAGKQVLENLNSKHGLSFNFIDLYAGFQTFQETGKALPDETVKVLKEQCQGALFGAVQSPTTKVEGYSSPIVALRREMGLFANVRPVKSVEGEKGKPIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIATRRIATIALDIALKRLQTRGQATLTVTHKSNVLSQSDGLFREICKEVYESNKDKYGQIKYNEQIVDSMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEPCHGSAPDIAGKGIANPIATIRSTALMLEFLGHNEAAQDIYKAVDANLREGSIKTPDLGGKASTQQVVDDVLSRL
SIO_010081: YIL094C
subclass of: SO_0000673
so part of: YIL094C
location: complement(186517..187632)
location: region:186517-187632:-1
so has part: feature:186517-187632:-1:exon

NP_012172.1
type: Protein
SIO_000068: ncbiprotein

S000001356
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:186517-187632:-1:exon

YIL093C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: mS23
gene: RSM25
locus tag: YIL093C
gene synonym: mS23
so part of: sequence
location: complement(<187990..>188784)
location: region:187990-188784:-1
so has part: feature:187990-188784:-1:exon
subclass of: SO_0000010

854715
type: Gene
SIO_000068: ncbigene

position:187990:-1
position: 187990
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:188784:-1
position: 188784
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:187990-188784:-1:exon

YIL093C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: mS23
gene: RSM25
locus tag: YIL093C
gene synonym: mS23
product: mitochondrial 37S ribosomal protein RSM25
transcript id: NM_001179441.3
SIO_010081: YIL093C
subclass of: SO_0000673
so part of: YIL093C
location: complement(<187990..>188784)
location: region:187990-188784:-1
so has part: feature:187990-188784:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:187990-188784:-1:exon

YIL093C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: mS23
gene: RSM25
locus tag: YIL093C
gene synonym: mS23
experiment: EXISTENCE:curator inference:GO:0032543 mitochondrial translation [PMID:11278769]
experiment: EXISTENCE:direct assay:GO:0003735 structural constituent of ribosome [PMID:11278769]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005763 mitochondrial small ribosomal subunit [PMID:11278769]
note: Mitochondrial ribosomal protein of the small subunit
codon start: 1
product: mitochondrial 37S ribosomal protein RSM25
translation: MKIQTNAVNVLQRTSAYLKSGLLKETPAWYNVVASIPPSTKFTREPRFKNPSNGHIIGKLVDVTEQPHANNKGLYKTRPNSSDKRVGVKRLYRPPKLTYVEDRLRSLFYKQHPWELSRPKILVENEIGDENYDWSHMLQIGRPLDGESVIQRTMYLIKTKQYGDMVEAYDHARYEFYALRMQEETEQQVALEEAEMFGSLFGVSAIEHGIQKEQEVLDVWEKKVVEETELMAARTSNPAGSWKDDTTLNTAQEEESTTSENLHF
SIO_010081: YIL093C
subclass of: SO_0000673
so part of: YIL093C
location: complement(187990..188784)
location: region:187990-188784:-1
so has part: feature:187990-188784:-1:exon

NP_012173.3
type: Protein
SIO_000068: ncbiprotein

S000001355
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:187990-188784:-1:exon

YIL092W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YIL092W
so part of: sequence
location: <189066..>190967
location: region:189066-190967:1
so has part: feature:189066-190967:1:exon
subclass of: SO_0000010

854716
type: Gene
SIO_000068: ncbigene

position:189066:1
position: 189066
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:190967:1
position: 190967
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:189066-190967:1:exon

YIL092W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YIL092W
product: uncharacterized protein
transcript id: NM_001179440.3
SIO_010081: YIL092W
subclass of: SO_0000673
so part of: YIL092W
location: <189066..>190967
location: region:189066-190967:1
so has part: feature:189066-190967:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:189066-190967:1:exon

YIL092W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YIL092W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
note: hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to the nucleus
codon start: 1
product: uncharacterized protein
translation: MVQMRSKNMAYESGTNNYSDTIANGNTLPPRSKKGHSGRRKRSETLPIACNNFCVTRQIDDDEQAFKMLDKVSHLKKFSAEDGDDNNIFVQWADDITDILFGLCCTGTFLKLLISSALSGRAKTWFDSTTEGIDDHVIKAYSFEKFLALLSEEFDGARSLRREIFTELLTLSIDSEKSLEAFAHKSGRLTPYYLSSGAALDLFLTKLEPQLQKQLENCAFPMTLNLALLITACEFAKRASNHKKYRYKNTRDSDICTPKSKNTAIVSKLSNTKTISKNKVIEKSDKKNYFDKNSQHIPDPKRRKQNEPGMRLFLVMDEEKNILTSRNVSANAYTSKNGHTNLSDLHTNLKNSKSQQCAVEPISILNSGSLVTGTINIDLINDEVLGTKEETTTYDERMDGNSRSLNERCCAVKKNSLQPITSNIFQKNAEIQGTKIGSVLDSGISNSFSSTEYMFPPTSSATVSNPVKKNEISKSSQVKDIAQFNPFMTNEKEKKLNPSESFKSPGVSMEINRLSRIAGLRNIPGNIYEDSKMLNLKTRKCYPLHNFAVRTRSAHFNDRPSNYISPHETINATLRSPASFDSIQCITRSKRVDAETNKATGSAKSENIETKSRKFPEVINPFLVNTTNKKESD
SIO_010081: YIL092W
subclass of: SO_0000673
so part of: YIL092W
location: 189066..190967
location: region:189066-190967:1
so has part: feature:189066-190967:1:exon

NP_012174.3
type: Protein
SIO_000068: ncbiprotein

S000001354
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:189066-190967:1:exon

YIL091C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: UTP25
locus tag: YIL091C
so part of: sequence
location: complement(<191030..>193195)
location: region:191030-193195:-1
so has part: feature:191030-193195:-1:exon
subclass of: SO_0000010

854717
type: Gene
SIO_000068: ncbigene

position:191030:-1
position: 191030
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:193195:-1
position: 193195
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:191030-193195:-1:exon

YIL091C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: UTP25
locus tag: YIL091C
product: rRNA-binding ribosome biosynthesis protein UTP25
transcript id: NM_001179439.1
SIO_010081: YIL091C
subclass of: SO_0000673
so part of: YIL091C
location: complement(<191030..>193195)
location: region:191030-193195:-1
so has part: feature:191030-193195:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:191030-193195:-1:exon

YIL091C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: UTP25
locus tag: YIL091C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:20528918|PMID:14562095|PMID:14690591]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:20528918|PMID:14562095|PMID:14690591]
experiment: EXISTENCE:direct assay:GO:0019843 rRNA binding [PMID:20528918]
experiment: EXISTENCE:direct assay:GO:0032040 small-subunit processome [PMID:20884785]
experiment: EXISTENCE:direct assay:GO:0034511 U3 snoRNA binding [PMID:20528918]
experiment: EXISTENCE:mutant phenotype:GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:20884785|PMID:20528918]
experiment: EXISTENCE:mutant phenotype:GO:0042274 ribosomal small subunit biogenesis [PMID:20884785|PMID:19806183|PMID:20528918]
experiment: EXISTENCE:physical interaction:GO:0032040 small-subunit processome [PMID:20528918]
note: Nucleolar protein; required for 35S pre-RNA processing and 40S ribosomal subunit biogenesis
codon start: 1
product: rRNA-binding ribosome biosynthesis protein UTP25
translation: MSDSSVREKNDNFRGYRKRGRQELRKIKRSSARTEGGSTETLEDVAEDIDHRSDEDEVSDVDSGDDFDIEDEEGKKEKVYDALLTILKSEHPEPKRRRREADESNKAPAEVGEDEHENTEHGPVDDQLEIENGLLGNHEDDNDDDSSGDEKDIDSEDEQDPFESHFNQVPEKFVDKLSNAFKTKSVKYKSVKGSLSDSESYIYAKPVVIGEEALVESPYRSSSIYSYFLKQRLKVQNGLLDKKTDPLTALQKKLVDPMFQYKDILYEYDSYEKDEDEYRDLYALHVLNHIYKTRDRILKNNQRLQDNPDTEHLDQGFTRPKVLIVVPTREVAYRVVDKIISKSGIDQVDKKGKFYDQFRDDSLPPKSKPKSFQHIFRGNTNDFFVVGLKFTRKAIKLYSNFYQSDIIVCSPLGIQMILENTDKKKRQDDFLSSIELMVIDQLHSIEYQNISHIFTIFDHLNKIPDQQHEADFSRIRMWYINEQAKLFRQTMVFTKYISPAANSLINGRCRNMAGRWKNHKVIGSENSSIGQSGLKIRQIFQRFDIIGNSIIEEPDYRFKFFTSVIIPGIVKSTGYEDGILIYIPDYTDFIRIRNYMKEKTTILFGDINEYSSQRQLNANRSLFQQGRLKVMLYTERLHHYRRYEIKGVKSVVFYKPPNNPEFYNEVVRFIGKNAFLGNTDLNISTVRCIYSKLDGLSLERIVGTKRAAVLSHAQKEIYEFK
SIO_010081: YIL091C
subclass of: SO_0000673
so part of: YIL091C
location: complement(191030..193195)
location: region:191030-193195:-1
so has part: feature:191030-193195:-1:exon

NP_012175.1
type: Protein
SIO_000068: ncbiprotein

S000001353
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:191030-193195:-1:exon

YIL090W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ICE2
locus tag: YIL090W
so part of: sequence
location: <193595..>195070
location: region:193595-195070:1
so has part: feature:193595-195070:1:exon
subclass of: SO_0000010

854718
type: Gene
SIO_000068: ncbigene

position:193595:1
position: 193595
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:195070:1
position: 195070
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:193595-195070:1:exon

YIL090W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ICE2
locus tag: YIL090W
product: Ice2p
transcript id: NM_001179438.1
SIO_010081: YIL090W
subclass of: SO_0000673
so part of: YIL090W
location: <193595..>195070
location: region:193595-195070:1
so has part: feature:193595-195070:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:193595-195070:1:exon

YIL090W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ICE2
locus tag: YIL090W
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:14562095|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:15585575]
experiment: EXISTENCE:direct assay:GO:0032541 cortical endoplasmic reticulum [PMID:15585575]
experiment: EXISTENCE:direct assay:GO:0097038 perinuclear endoplasmic reticulum [PMID:15585575]
experiment: EXISTENCE:genetic interaction:GO:0000921 septin ring assembly [PMID:17984322]
experiment: EXISTENCE:genetic interaction:GO:0004865 protein serine/threonine phosphatase inhibitor activity [PMID:34617598]
experiment: EXISTENCE:genetic interaction:GO:0160031 endoplasmic reticulum membrane biogenesis [PMID:34617598]
experiment: EXISTENCE:mutant phenotype:GO:0000921 septin ring assembly [PMID:17984322]
experiment: EXISTENCE:mutant phenotype:GO:0004865 protein serine/threonine phosphatase inhibitor activity [PMID:34617598]
experiment: EXISTENCE:mutant phenotype:GO:0006882 cellular zinc ion homeostasis [PMID:22685415]
experiment: EXISTENCE:mutant phenotype:GO:0031204 post-translational protein targeting to membrane, translocation [PMID:32513868]
experiment: EXISTENCE:mutant phenotype:GO:0036228 protein localization to nuclear inner membrane [PMID:15911569]
experiment: EXISTENCE:mutant phenotype:GO:0048309 endoplasmic reticulum inheritance [PMID:15585575|PMID:17984322]
experiment: EXISTENCE:mutant phenotype:GO:0160031 endoplasmic reticulum membrane biogenesis [PMID:34617598]
note: Integral ER membrane protein with type-III transmembrane domains; promotes ER membrane expansion by inhibiting the Nem1-Spo7 phosphatase complex, resulting in reduced dephosphorylation and activation of Pah1p; maintains homeostasis during ER stress; required for post-translational SRP-independent protein translocation into the ER; necessary for efficient targeting of the Trm1p to the inner nuclear membrane; mutations cause defects in cortical ER morphology; member of the SERINC superfamily
codon start: 1
product: Ice2p
translation: MTSLSKSFMQSGRICAACFYLLFTLLSIPISFKVGGLECGLSFTVTLFTLYFITTTLNVLARRHGGRLYIFFTNCLYYSQHFIIASLLYLFLSGFSNDELGNVLKNKYNESESFLEALKNSLNSNQINYVLYYYYYRFVVQPWQFVLTKSTPFFTLSEGFFTILAIQAVGETNRWLSNDLNSNTWIISSLLTSGGVITASLYYLYRIYVTPIWPLSIQTASLLGLVLSMVCGLGLYGIVSQKGSVIESSLFFAYIVRCIYEISPKLATTATDEILNLFKDVWQKHQRNLPTADNLLCYFHNVILKNAEVLWGSFIPRGRKKTGDFHDKLISILSFEKVSLISKPFWKFFKNFTFSVPLSINEFCQVTIKMASESVSPAIVINLCFRVLMFYSATRIIPALQRKNDKQLRKSRRIMKGLYWYSPCILIAMYTHLILQYSGELKKDLCIWGCSEKWFGVDQPEIIVDSWGFWNWCNIFCTILVYATELIGSGS
SIO_010081: YIL090W
subclass of: SO_0000673
so part of: YIL090W
location: 193595..195070
location: region:193595-195070:1
so has part: feature:193595-195070:1:exon

NP_012176.1
type: Protein
SIO_000068: ncbiprotein

S000001352
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:193595-195070:1:exon

YIL089W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YIL089W
so part of: sequence
location: <195599..>196216
location: region:195599-196216:1
so has part: feature:195599-196216:1:exon
subclass of: SO_0000010

854719
type: Gene
SIO_000068: ncbigene

position:195599:1
position: 195599
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:196216:1
position: 196216
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:195599-196216:1:exon

YIL089W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YIL089W
product: uncharacterized protein
transcript id: NM_001179437.1
SIO_010081: YIL089W
subclass of: SO_0000673
so part of: YIL089W
location: <195599..>196216
location: region:195599-196216:1
so has part: feature:195599-196216:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:195599-196216:1:exon

YIL089W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YIL089W
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0000328 fungal-type vacuole lumen [PMID:21777356]
experiment: EXISTENCE:direct assay:GO:0005777 peroxisome [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:21777356]
note: hypothetical protein found in the ER and vacuole lumen; overexpression of YIL089W affects endocytic protein trafficking
codon start: 1
product: uncharacterized protein
translation: MQRTRELESSVAIDQTEVPRSRFFIMVKKLSRVADIVYIVDTFLIPPLHPLKKQHPKVAKFLKVQLVFDLISLFIFATHQLLLLEDGNFGKHYFKRKTKRCSKFSCSRCNANAHHPKWFKFKHSLLCLGTFCFGVYSLVKINKFFKTDQTVDLNRLLELFFWQLNAILNMKLFAFYGDHLESHSAPLDVYEDSFANKSSSGGDEV
SIO_010081: YIL089W
subclass of: SO_0000673
so part of: YIL089W
location: 195599..196216
location: region:195599-196216:1
so has part: feature:195599-196216:1:exon

NP_012177.1
type: Protein
SIO_000068: ncbiprotein

S000001351
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:195599-196216:1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty4 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(196653..197023)
location: region:196653-197023:-1
so has part: feature:196653-197023:-1:region

S000007015
type: SGD
SIO_000068: sgd

position:196653:-1
position: 196653
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:197023:-1
position: 197023
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:196653-197023:-1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(197140..197488)
location: region:197140-197488:-1
so has part: feature:197140-197488:-1:region

S000007011
type: SGD
SIO_000068: sgd

position:197140:-1
position: 197140
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:197488:-1
position: 197488
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:197140-197488:-1:region

YNCI0004W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCI0004W
so part of: sequence
location: 197592..197663
location: region:197592-197663:1
so has part: feature:197592-197663:1:exon
subclass of: SO_0000663

854720
type: Gene
SIO_000068: ncbigene

position:197592:1
position: 197592
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:197663:1
position: 197663
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:197592-197663:1:exon

YNCI0004W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCI0004W
product: tRNA-Glu
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Glutamate tRNA (tRNA-Glu), predicted by tRNAscan-SE analysis
SIO_010081: YNCI0004W
subclass of: SO_0000673
so part of: YNCI0004W
location: 197592..197663
location: region:197592-197663:1
so has part: feature:197592-197663:1:exon

S000006547
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:197592-197663:1:exon

YIL088C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: AVT7
locus tag: YIL088C
so part of: sequence
location: complement(<197931..>199403)
location: region:197931-199403:-1
so has part: feature:197931-199403:-1:exon
subclass of: SO_0000010

854721
type: Gene
SIO_000068: ncbigene

position:197931:-1
position: 197931
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:199403:-1
position: 199403
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:197931-199403:-1:exon

YIL088C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: AVT7
locus tag: YIL088C
product: Avt7p
transcript id: NM_001179436.1
SIO_010081: YIL088C
subclass of: SO_0000673
so part of: YIL088C
location: complement(<197931..>199403)
location: region:197931-199403:-1
so has part: feature:197931-199403:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:197931-199403:-1:exon

YIL088C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: AVT7
locus tag: YIL088C
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:11274162|PMID:27246536|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005774 vacuolar membrane [PMID:25266154]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:11274162]
experiment: EXISTENCE:mutant phenotype:GO:0006865 amino acid transport [PMID:25266154]
experiment: EXISTENCE:mutant phenotype:GO:0043937 regulation of sporulation [PMID:25266154]
note: Vacuolar amino acid transporter; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters
codon start: 1
product: Avt7p
translation: MEATSSALSSTANLVKTIVGAGTLAIPYSFKSDGVLVGVILTLLAAVTSGLGLFVLSKCSKTLINPRNSSFFTLCMLTYPTLAPIFDLAMIVQCFGVGLSYLVLIGDLFPGLFGGERNYWIIASAVIIIPLCLVKKLDQLKYSSILGLFALAYISILVFSHFVFELGKGELTNILRNDICWWKIHDFKGLLSTFSIIIFAFTGSMNLFPMINELKDNSMENITFVINNSISLSTALFLIVGLSGYLTFGNETLGNLMLNYDPNSIWIVIGKFCLGSMLILSFPLLFHPLRIAVNNVIIWIEITYGGANPEEDPQVSEYTRASNLRPISMTVEDPAQPSDALDATSYNEQECLLPNGNFDNGSIESQENNNDERGTMAVAGDNEHHAPFVKSRFYWITALLLISMYTLALSVQSFALVLSFVGATGSTSISFTLPGLLGYKLIGLDSLAIGKMIPPKDRFYKRCSLLLVFYGLSVMFLSLYVTVFNRSDEA
SIO_010081: YIL088C
subclass of: SO_0000673
so part of: YIL088C
location: complement(197931..199403)
location: region:197931-199403:-1
so has part: feature:197931-199403:-1:exon

NP_012178.1
type: Protein
SIO_000068: ncbiprotein

S000001350
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:197931-199403:-1:exon

YIL087C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: AIM19
locus tag: YIL087C
so part of: sequence
location: complement(<199646..>200119)
location: region:199646-200119:-1
so has part: feature:199646-200119:-1:exon
subclass of: SO_0000010

854722
type: Gene
SIO_000068: ncbigene

position:199646:-1
position: 199646
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:200119:-1
position: 200119
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:199646-200119:-1:exon

YIL087C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: AIM19
locus tag: YIL087C
product: Aim19p
transcript id: NM_001179435.3
SIO_010081: YIL087C
subclass of: SO_0000673
so part of: YIL087C
location: complement(<199646..>200119)
location: region:199646-200119:-1
so has part: feature:199646-200119:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:199646-200119:-1:exon

YIL087C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: AIM19
locus tag: YIL087C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095|PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:physical interaction:GO:0005739 mitochondrion [PMID:25124039]
note: hypothetical protein; mitochondrial protein that physically interacts with Tim23p; null mutant displays reduced respiratory growth
codon start: 1
product: Aim19p
translation: MSAKPATDDAKDELLSPFRRLYALTRTPYPALANAALLASTPVLSPSFKVPPTQSPALSIPMSRVFSKSSTARIGITTKTALFFSTMQAIGAYMIYDNDLENGAGFIATWSALYLIVGGKKSFSALRYGRTWPLVLSSVSLANAVLYGQRFLATGFQ
SIO_010081: YIL087C
subclass of: SO_0000673
so part of: YIL087C
location: complement(199646..200119)
location: region:199646-200119:-1
so has part: feature:199646-200119:-1:exon

NP_012179.3
type: Protein
SIO_000068: ncbiprotein

S000001349
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:199646-200119:-1:exon

YIL086C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YIL086C
so part of: sequence
location: complement(<200153..>200461)
location: region:200153-200461:-1
so has part: feature:200153-200461:-1:exon
subclass of: SO_0000010

854723
type: Gene
SIO_000068: ncbigene

position:200153:-1
position: 200153
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:200461:-1
position: 200461
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:200153-200461:-1:exon

YIL086C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YIL086C
product: uncharacterized protein
transcript id: NM_001348844.1
SIO_010081: YIL086C
subclass of: SO_0000673
so part of: YIL086C
location: complement(<200153..>200461)
location: region:200153-200461:-1
so has part: feature:200153-200461:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:200153-200461:-1:exon

YIL086C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YIL086C
note: hypothetical protein; conserved across S. cerevisiae strains
codon start: 1
product: uncharacterized protein
translation: MNKIIKESTNFSRYLRTGGVLNSLRTTSKFVYINNNSYLTHGGFDGNVATIFNISEFNYINSSAKGSLLTYKSITFFCPRYFKKRPLGRHAKGKGKSDEKIL
SIO_010081: YIL086C
subclass of: SO_0000673
so part of: YIL086C
location: complement(200153..200461)
location: region:200153-200461:-1
so has part: feature:200153-200461:-1:exon

NP_001335784.1
type: Protein
SIO_000068: ncbiprotein

S000001348
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:200153-200461:-1:exon

YIL085C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: KTR7
locus tag: YIL085C
so part of: sequence
location: complement(<200490..>202043)
location: region:200490-202043:-1
so has part: feature:200490-202043:-1:exon
subclass of: SO_0000010

854724
type: Gene
SIO_000068: ncbigene

position:200490:-1
position: 200490
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:202043:-1
position: 202043
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:200490-202043:-1:exon

YIL085C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: KTR7
locus tag: YIL085C
product: putative mannosyltransferase
transcript id: NM_001179433.3
SIO_010081: YIL085C
subclass of: SO_0000673
so part of: YIL085C
location: complement(<200490..>202043)
location: region:200490-202043:-1
so has part: feature:200490-202043:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:200490-202043:-1:exon

YIL085C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: KTR7
locus tag: YIL085C
experiment: EXISTENCE:mutant phenotype:GO:0031505 fungal-type cell wall organization [PMID:9090056]
note: Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family; KTR7 has a paralog, KTR5, that arose from the whole genome duplication
codon start: 1
product: putative mannosyltransferase
translation: MAIRLNPKVRRFLLDKCRQKRYGFLFLGCIFAILYCMGTWPFFAKDIVHDPNNLPYSLQDYSTDKDEPFFRGCTDTKLYLQNPAYSKMNASFVMLTRNEEIEDVLKTMRSIEGHFNKWFKYPYVFLNDDPFTDHFKDQIQAATNATVEFGTVDEIMWEFPAKVRNSLQFKASLEDQNDRGIMYGNMESYHKMCRFYSGIFYKHPLVSKYEWYWRIEPDVDFFCDISYDPFFEMAKHNKKYGFTVLITELYWTVPNLFRTTKSFIKKTAGLKENLGTLWKLFTFNYNILDTDDEEISRWVNFPWDAKPKLTEKLMVDFLLENHGQVNNEEDLEGIQYLVERARSKVPMLEDSLEGEDYNLCHFWSNFEIARVDLFDNEIYNAYFKFLEESGGFWTERWGDAPIHSIGLGMTLDLEDVHYFRDIGYRHSSLQHCPKNALQSQENLNTFDEGYNFGCGCRCVCPKKGEDIEDHSTPCMDIFFELLHGREYEKEFPGCYKPSIKDKDVIEEIRRENFRVIE
SIO_010081: YIL085C
subclass of: SO_0000673
so part of: YIL085C
location: complement(200490..202043)
location: region:200490-202043:-1
so has part: feature:200490-202043:-1:exon

NP_012181.3
type: Protein
SIO_000068: ncbiprotein

S000001347
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:200490-202043:-1:exon

YIL084C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SDS3
locus tag: YIL084C
so part of: sequence
location: complement(<202276..>203259)
location: region:202276-203259:-1
so has part: feature:202276-203259:-1:exon
subclass of: SO_0000010

854725
type: Gene
SIO_000068: ncbigene

position:202276:-1
position: 202276
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:203259:-1
position: 203259
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:202276-203259:-1:exon

YIL084C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SDS3
locus tag: YIL084C
product: Sds3p
transcript id: NM_001179432.1
SIO_010081: YIL084C
subclass of: SO_0000673
so part of: YIL084C
location: complement(<202276..>203259)
location: region:202276-203259:-1
so has part: feature:202276-203259:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:202276-203259:-1:exon

YIL084C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SDS3
locus tag: YIL084C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0033698 Rpd3L complex [PMID:16286007|PMID:16286008|PMID:16314178|PMID:19040720]
experiment: EXISTENCE:direct assay:GO:0070210 Rpd3L-Expanded complex [PMID:19040720]
experiment: EXISTENCE:mutant phenotype:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:24358376]
experiment: EXISTENCE:mutant phenotype:GO:0004407 histone deacetylase activity [PMID:11024051]
experiment: EXISTENCE:mutant phenotype:GO:0031507 heterochromatin formation [PMID:11024051]
experiment: EXISTENCE:mutant phenotype:GO:0043709 cell adhesion involved in single-species biofilm formation [PMID:18202364]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:17210643|PMID:20398213]
experiment: EXISTENCE:mutant phenotype:GO:0061186 negative regulation of silent mating-type cassette heterochromatin formation [PMID:16286008]
experiment: EXISTENCE:mutant phenotype:GO:0061188 negative regulation of rDNA heterochromatin formation [PMID:16286008]
experiment: EXISTENCE:mutant phenotype:GO:0061408 positive regulation of transcription from RNA polymerase II promoter in response to heat stress [PMID:20398213]
experiment: EXISTENCE:mutant phenotype:GO:2000217 regulation of invasive growth in response to glucose limitation [PMID:18202364]
note: Component of the Rpd3L histone deacetylase complex; required for its structural integrity and catalytic activity, involved in transcriptional silencing and required for sporulation; relocalizes to the cytosol in response to hypoxia; cells defective in SDS3 display pleiotropic phenotypes
codon start: 1
product: Sds3p
translation: MAIQKVSNKDLSRKDKRRFNIESKVNKIYQNFYSERDNQYKDRLTALQTDLTSLHQGDNGQYARQVRDLEEERDLELVRLRLFEEYRVSRSGIEFQEDIEKAKAEHEKLIKLCKERLYSSIEQKIKKLQEERLLMDVANVHSYAMNYSRPQYQKNTRSHTVSGWDSSSNEYGRDTANESATDTGAGNDRRTLRRRNASKDTRGNNNNQDESDFQTGNGSGSNGHGSRQGSQFPHFNNLTYKSGMNSDSDFLQGINEGTDLYAFLFGEKNPKDNANGNEKKKNRGAQRYSTKTAPPLQSLKPDEVTEDISLIRELTGQPPAPFRLRSD
SIO_010081: YIL084C
subclass of: SO_0000673
so part of: YIL084C
location: complement(202276..203259)
location: region:202276-203259:-1
so has part: feature:202276-203259:-1:exon

NP_012182.1
type: Protein
SIO_000068: ncbiprotein

S000001346
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:202276-203259:-1:exon

YIL083C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CAB2
locus tag: YIL083C
so part of: sequence
location: complement(<203556..>204653)
location: region:203556-204653:-1
so has part: feature:203556-204653:-1:exon
subclass of: SO_0000010

854726
type: Gene
SIO_000068: ncbigene

position:203556:-1
position: 203556
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:204653:-1
position: 204653
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:203556-204653:-1:exon

YIL083C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CAB2
locus tag: YIL083C
product: phosphopantothenate--cysteine ligase CAB2
transcript id: NM_001179431.2
SIO_010081: YIL083C
subclass of: SO_0000673
so part of: YIL083C
location: complement(<203556..>204653)
location: region:203556-204653:-1
so has part: feature:203556-204653:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:203556-204653:-1:exon

YIL083C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CAB2
locus tag: YIL083C
EC number: 6.3.2.5
experiment: EXISTENCE:direct assay:GO:0004632 phosphopantothenate--cysteine ligase activity [PMID:30653991]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14690591]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14690591]
experiment: EXISTENCE:direct assay:GO:1990143 CoA-synthesizing protein complex [PMID:23789928]
experiment: EXISTENCE:genetic interaction:GO:0015937 coenzyme A biosynthetic process [PMID:19266201]
note: Phosphopantothenoylcysteine synthetase (PPCS); catalyzes the second step of coenzyme A biosynthesis from pantothenate; subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) that contains: Cab2p, Cab3p, Cab4p, Cab5p, Sis2p and Vhs3p subunits; null mutant lethality is complemented by human homolog PPCS and by E. coli coaBC, a bifunctional enzyme with PPCS activity
codon start: 1
product: phosphopantothenate--cysteine ligase CAB2
translation: MPPLPVLNRPQIHTSVTEISHAIDRTIKEELFPVAYTTEEEQYFKTNPKPAYIDELIKDAKEFIDLQYSLKRNKIVLITSGGTTVPLENNTVRFIDNFSAGTRGASSAEQFLANGYSVIFLHREFSLTPYNRSFSHSINTLFLDYIDSEGKIKPEFAENVLKNKKLYDKYMEKEEKLLLLPFTTVNQYLWSLKSIAKLLNNSGCLFYLAAAVSDFFVPYSRLPQHKIQSGDNGKMGANNDTEGTTRTTPDGKLIVNLDPVPKFLRRLVESWATQAMIVSFKLETDESMLLYKCTQALDRYNHQLVIGNLLQTRNKQVIFVSPENRKGDWVRLDEKHHSIEEMIIPEVIARHDKWVAHSKTKLATK
SIO_010081: YIL083C
subclass of: SO_0000673
so part of: YIL083C
location: complement(203556..204653)
location: region:203556-204653:-1
so has part: feature:203556-204653:-1:exon

NP_012183.2
type: Protein
SIO_000068: ncbiprotein

S000001345
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:203556-204653:-1:exon

mobile_element
type: Mobile Element
subclass of: SO_0001037
RO_0002162: 559292
note: YILWTy3-1; Ty3 element, LTR retrotransposon of the Gypsy (Metaviridae) group; contains co-transcribed genes TYA Gag and TYB Pol, encoding proteins involved in structure and function of virus-like particles, flanked by two direct repeats; transposition is induced upon exposure to mating pheromone
mobile element type: retrotransposon:YILWTy3-1
so part of: sequence
location: 205220..210647
location: region:205220-210647:1
so has part: feature:205220-210647:1:region

S000007020
type: SGD
SIO_000068: sgd

position:205220:1
position: 205220
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:210647:1
position: 210647
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:205220-210647:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty3 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 205220..205559
location: region:205220-205559:1
so has part: feature:205220-205559:1:region

S000007017
type: SGD
SIO_000068: sgd

position:205559:1
position: 205559
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:205220-205559:1:region

YIL082W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YIL082W-A
so part of: sequence
location: <205635..>210132
location: region:205635-210132:1
so has part: feature:205635-210132:1:exon
subclass of: SO_0000010

854728
type: Gene
SIO_000068: ncbigene

position:205635:1
position: 205635
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:210132:1
position: 210132
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:205635-210132:1:exon

YIL082W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YIL082W-A
product: gag-pol fusion protein
transcript id: NM_001181434.4
SIO_010081: YIL082W-A
subclass of: SO_0000673
so part of: YIL082W-A
location: <205635..>210132
location: region:205635-210132:1
so has part: feature:205635-210132:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:205635-210132:1:exon

YIL082W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YIL082W-A
EC number: 2.7.7.7
EC number: 2.7.7.49
EC number: 3.1.26.4
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:9448009]
ribosomal slippage: true
note: Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes
codon start: 1
product: gag-pol fusion protein
translation: MSFMDQIPGGGNYPKLPVECLPNFPIQPSLTFRGRNDSHKLKNFISEIMLNMSMISWPNDASRIVYCRRHLLNPAAQWANDFVQEQGILEITFDTFIQGLYQHFYKPPDINKIFNAITQLSEAKLGIERLNQRFRKIWDRMPPDFMTEKAAIMTYTRLLTKETYNIVRMHKPETLKDAMEEAYQTTALTERFFPGFELDADGDTIIGATTHLQEEYDSDYDSEDNLTQNRYVHTVRTRRSYNKPMSNHRNRRNNNASREECIKNRLCFYCKKEGHRLNECRARKRVLTDLELESKDQQTLFIKTLPIVHYIAIPEMDNTAEKTIKIQNTKVKTLFDSGSPTSFIRRDIVELLKYEIYETPPLRFRGFVATKSAVTSEAVTIDLKINDLQITLAAYILDNMDYQLLIGNPILRRYPKILHTVLNTRESPDSLKPKTYRSETVNNVRTYSAGNRGNPRNIKLSFAPTILEATDPKSAGNRGNPRNTKLSLAPTILEATDPKSAGNRGDSRTKTLSLATTTPAAIDPLTTLDNPGSTQSTFAQFPIPEEASILEEDGKYSNVVSTIQSVEPNATDHSNKDTFCTLPVWLQQKYREIIRNDLPPRPADINNIPVKHDIEIKPGARLPRLQPYHVTEKNEQEINKIVQKLLDNKFIVPSKSPCSSPVVLVPKKDGTFRLCVDYRTLNKATISDPFPLPRIDNLLSRIGNAQIFTTLDLHSGYHQIPMEPKDRYKTAFVTPSGKYEYTVMPFGLVNAPSTFARYMADTFRDLRFVNVYLDDILIFSESPEEHWKHLDTVLERLKNENLIVKKKKCKFASEETEFLGYSIGIQKIAPLQHKCAAIRDFPTPKTVKQAQRFLGMINYYRRFIPNCSKIAQPIQLFICDKSQWTEKQDKAIEKLKAALCNSPVLVPFNNKANYRLTTDASKDGIGAVLEEVDNKNKLVGVVGYFSKSLESAQKNYPAGELELLGIIKALHHFRYMLHGKHFTLRTDHISLLSLQNKNEPARRVQRWLDDLATYDFTLEYLAGPKNVVADAISRAIYTITPETSRPIDTESWKSYYKSDPLCSAVLIHMKELTQHNVTPEDMSAFRSYQKKLELSETFRKNYSLEDEMIYYQDRLVVPIKQQNAVMRLYHDHTLFGGHFGVTVTLAKISPIYYWPKLQHSIIQYIRTCVQCQLIKSHRPRLHGLLQPLPIAEGRWLDISMDFVTGLPPTSNNLNMILVVVDRFSKRAHFIATRKTLDATQLIDLLFRYIFSYHGFPRTITSDRDVRMTADKYQELTKRLGIKSTMSSANHPQTDGQSERTIQTLNRLLRAYVSTNIQNWHVYLPQIEFVYNSTPTRTLGKSPFEIDLGYLPNTPAIKSDDEVNARSFTAVELAKHLKALTIQTKEQLEHAQIEMETNNNQRRKPLLLNIGDHVLVHRDAYFKKGAYMKVQQIYVGPFRVVKKINDNAYELDLNSHKKKHRVINVQFLKSLYTVQTRTQRINQSAPLRELREHTKLLHS
SIO_010081: YIL082W-A
subclass of: SO_0000673
so part of: YIL082W-A
location: join(205635..206485,206487..210132)
location: region:205635-210132:1
so has part: feature:205635-206485:1:exon
so has part: feature:206487-210132:1:exon

NP_012184.1
type: Protein
SIO_000068: ncbiprotein

S000003537
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:205635-206485:1:exon

position:206485:1
position: 206485
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:206487-210132:1:exon

position:206487:1
position: 206487
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty3 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 210308..210647
location: region:210308-210647:1
so has part: feature:210308-210647:1:region

S000007018
type: SGD
SIO_000068: sgd

position:210308:1
position: 210308
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:210308-210647:1:region

YNCI0005W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCI0005W
so part of: sequence
location: 210665..210738
location: region:210665-210738:1
so has part: feature:210665-210738:1:exon
subclass of: SO_0000663

854730
type: Gene
SIO_000068: ncbigene

position:210665:1
position: 210665
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:210738:1
position: 210738
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:210665-210738:1:exon

YNCI0005W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCI0005W
product: tRNA-Ile
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Isoleucine tRNA (tRNA-Ile), predicted by tRNAscan-SE analysis
SIO_010081: YNCI0005W
subclass of: SO_0000673
so part of: YNCI0005W
location: 210665..210738
location: region:210665-210738:1
so has part: feature:210665-210738:1:exon

S000006606
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:210665-210738:1:exon

YIL079C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: AIR1
locus tag: YIL079C
so part of: sequence
location: complement(<210923..>212005)
location: region:210923-212005:-1
so has part: feature:210923-212005:-1:exon
subclass of: SO_0000010

854731
type: Gene
SIO_000068: ncbigene

position:210923:-1
position: 210923
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:212005:-1
position: 212005
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:210923-212005:-1:exon

YIL079C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: AIR1
locus tag: YIL079C
product: TRAMP complex RNA-binding subunit
transcript id: NM_001179429.1
SIO_010081: YIL079C
subclass of: SO_0000673
so part of: YIL079C
location: complement(<210923..>212005)
location: region:210923-212005:-1
so has part: feature:210923-212005:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:210923-212005:-1:exon

YIL079C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: AIR1
locus tag: YIL079C
experiment: EXISTENCE:direct assay:GO:0004652 polynucleotide adenylyltransferase activity [PMID:15935759]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:11489916]
experiment: EXISTENCE:direct assay:GO:0031499 TRAMP complex [PMID:15828860|PMID:15935759]
experiment: EXISTENCE:direct assay:GO:0043629 ncRNA polyadenylation [PMID:15828860]
experiment: EXISTENCE:direct assay:GO:0071038 nuclear polyadenylation-dependent tRNA catabolic process [PMID:15828860|PMID:17643380]
experiment: EXISTENCE:genetic interaction:GO:0004652 polynucleotide adenylyltransferase activity [PMID:15935759]
experiment: EXISTENCE:genetic interaction:GO:0071031 nuclear mRNA surveillance of mRNA 3'-end processing [PMID:17410208]
experiment: EXISTENCE:genetic interaction:GO:0071035 nuclear polyadenylation-dependent rRNA catabolic process [PMID:15935758|PMID:18007593]
experiment: EXISTENCE:genetic interaction:GO:0071036 nuclear polyadenylation-dependent snoRNA catabolic process [PMID:15935758]
experiment: EXISTENCE:genetic interaction:GO:0071037 nuclear polyadenylation-dependent snRNA catabolic process [PMID:15935758]
experiment: EXISTENCE:genetic interaction:GO:0071039 nuclear polyadenylation-dependent CUT catabolic process [PMID:18591258]
note: Zinc knuckle protein; involved in nuclear RNA processing and degradation as a component of the TRAMP complex; stimulates the poly(A) polymerase activity of Pap2p in vitro; AIR1 has a paralog, AIR2, that arose from the whole genome duplication; although Air1p and Air2p are homologous TRAMP subunits, they have nonredundant roles in regulation of substrate specificity of the exosome
codon start: 1
product: TRAMP complex RNA-binding subunit
translation: MSTLLSEVESIDTLPYVKDTTPTGSDSSSFNKLLAPSIEDVDANPEELRTLRGQGRYFGITDYDSNGAIMEAEPKCNNCSQRGHLKRNCPHVICTYCGFMDDHYSQHCPKAIICTNCNANGHYKSQCPHKWKKVFCTLCNSKRHSRERCPSIWRSYLLKTKDANQGDFDFQTVFCYNCGNAGHFGDDCAERRSSRVPNTDGSAFCGDNLATKFKQHYFNQLKDYKREASQRQHFDNEHEFNLLDYEYNDDAYDLPGSRTYRDKMKWKGKVQSTRNKNSSNNRYESSNNRKKKSPFSAQNYKVTKNKRVQTHPLDFPRSSQNNRTNDYSSQFSYNRDDFPKGPKNKRGRSSSNKSQRNGRY
SIO_010081: YIL079C
subclass of: SO_0000673
so part of: YIL079C
location: complement(210923..212005)
location: region:210923-212005:-1
so has part: feature:210923-212005:-1:exon

NP_012186.1
type: Protein
SIO_000068: ncbiprotein

S000001341
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:210923-212005:-1:exon

YIL078W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: THS1
locus tag: YIL078W
so part of: sequence
location: <212499..>214703
location: region:212499-214703:1
so has part: feature:212499-214703:1:exon
subclass of: SO_0000010

854732
type: Gene
SIO_000068: ncbigene

position:212499:1
position: 212499
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:214703:1
position: 214703
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:212499-214703:1:exon

YIL078W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: THS1
locus tag: YIL078W
product: threonine--tRNA ligase THS1
transcript id: NM_001179428.3
SIO_010081: YIL078W
subclass of: SO_0000673
so part of: YIL078W
location: <212499..>214703
location: region:212499-214703:1
so has part: feature:212499-214703:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:212499-214703:1:exon

YIL078W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: THS1
locus tag: YIL078W
EC number: 6.1.1.3
experiment: EXISTENCE:direct assay:GO:0004829 threonine-tRNA ligase activity [PMID:8143729]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0006435 threonyl-tRNA aminoacylation [PMID:8143729]
experiment: EXISTENCE:mutant phenotype:GO:0005737 cytoplasm [PMID:2995918]
note: Threonyl-tRNA synthetase; essential cytoplasmic protein; human homolog TARS can complement yeast null mutant
codon start: 1
product: threonine--tRNA ligase THS1
translation: MSASEAGVTEQVKKLSVKDSSNDAVKPNKKENKKSKQQSLYLDPEPTFIEERIEMFDRLQKEYNDKVASMPRVPLKIVLKDGAVKEATSWETTPMDIAKGISKSLADRLCISKVNGQLWDLDRPFEGEANEEIKLELLDFESDEGKKVFWHSSAHVLGESCECHLGAHICLGPPTDDGFFYEMAVRDSMKDISESPERTVSQADFPGLEGVAKNVIKQKQKFERLVMSKEDLLKMFHYSKYKTYLVQTKVPDGGATTVYRCGKLIDLCVGPHIPHTGRIKAFKLLKNSSCYFLGDATNDSLQRVYGISFPDKKLMDAHLKFLAEASMRDHRKIGKEQELFLFNEMSPGSCFWLPHGTRIYNTLVDLLRTEYRKRGYEEVITPNMYNSKLWETSGHWANYKENMFTFEVEKETFGLKPMNCPGHCLMFKSRERSYRELPWRVADFGVIHRNEFSGALSGLTRVRRFQQDDAHIFCTHDQIESEIENIFNFLQYIYGVFGFEFKMELSTRPEKYVGKIETWDAAESKLESALKKWGGNWEINAGDGAFYGPKIDIMISDALRRWHQCATIQLDFQLPNRFELEFKSKDQDSESYERPVMIHRAILGSVERMTAILTEHFAGKWPFWLSPRQVLVVPVGVKYQGYAEDVRNKLHDAGFYADVDLTGNTLQKKVRNGQMLKYNFIFIVGEQEMNEKSVNIRNRDVMEQQGKNATVSVEEVLKQLRNLKDEKRGDNVLA
SIO_010081: YIL078W
subclass of: SO_0000673
so part of: YIL078W
location: 212499..214703
location: region:212499-214703:1
so has part: feature:212499-214703:1:exon

NP_116578.3
type: Protein
SIO_000068: ncbiprotein

S000001340
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:212499-214703:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS901; Autonomously Replicating Sequence
so part of: sequence
location: 214624..214754
location: region:214624-214754:1
so has part: feature:214624-214754:1:region

S000007644
type: SGD
SIO_000068: sgd

position:214624:1
position: 214624
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:214754:1
position: 214754
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:214624-214754:1:region

YIL077C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MRX17
gene: RCI37
locus tag: YIL077C
gene synonym: MRX17
so part of: sequence
location: complement(<214991..>215953)
location: region:214991-215953:-1
so has part: feature:214991-215953:-1:exon
subclass of: SO_0000010

854733
type: Gene
SIO_000068: ncbigene

position:214991:-1
position: 214991
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:215953:-1
position: 215953
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:214991-215953:-1:exon

YIL077C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MRX17
gene: RCI37
locus tag: YIL077C
gene synonym: MRX17
product: Rci37p
transcript id: NM_001179427.3
SIO_010081: YIL077C
subclass of: SO_0000673
so part of: YIL077C
location: complement(<214991..>215953)
location: region:214991-215953:-1
so has part: feature:214991-215953:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:214991-215953:-1:exon

YIL077C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MRX17
gene: RCI37
locus tag: YIL077C
gene synonym: MRX17
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095|PMID:16823961]
note: Protein that associates with the large mitoribosomal subunit; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO)
codon start: 1
product: Rci37p
translation: MLGKEEEQQYGQNGKGMENELPFMKRPWFKKAYENAIEFHEKDELLDARDRLELSKAYRSIAKAEMWGGWLGFSAVFLTPFAYRYYKTKAIKGVKVPRNFVLGVMALFFATNFAGRSMYTRQLNERDPTGVLKDNYSNKYGDNDFGAFQHDQTKEIPRNQRQYNMMRLLDSGSPSRWSMYFYITYQNPERRLPDPKVKLQQMKKGGVFNGSPFMNQRDPIGLYRNKGRKSPDPIEGEQNDSPVLSSWEKIRNGDNSSSSSWENIRNTSRDQSQESDASVDHESDIFISGFSDDGNATDNSSSDDKYQRLLQSGRYGGNRS
SIO_010081: YIL077C
subclass of: SO_0000673
so part of: YIL077C
location: complement(214991..215953)
location: region:214991-215953:-1
so has part: feature:214991-215953:-1:exon

NP_012188.3
type: Protein
SIO_000068: ncbiprotein

S000001339
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:214991-215953:-1:exon

YIL076W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ANU2
gene: SEC28
locus tag: YIL076W
gene synonym: ANU2
so part of: sequence
location: <216658..>217548
location: region:216658-217548:1
so has part: feature:216658-217548:1:exon
subclass of: SO_0000010

854734
type: Gene
SIO_000068: ncbigene

position:216658:1
position: 216658
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:217548:1
position: 217548
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:216658-217548:1:exon

YIL076W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ANU2
gene: SEC28
locus tag: YIL076W
gene synonym: ANU2
product: coatomer subunit epsilon
transcript id: NM_001179426.1
SIO_010081: YIL076W
subclass of: SO_0000673
so part of: YIL076W
location: <216658..>217548
location: region:216658-217548:1
so has part: feature:216658-217548:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:216658-217548:1:exon

YIL076W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ANU2
gene: SEC28
locus tag: YIL076W
gene synonym: ANU2
experiment: EXISTENCE:direct assay:GO:0005768 endosome [PMID:17101773]
experiment: EXISTENCE:direct assay:GO:0030126 COPI vesicle coat [PMID:21435344]
experiment: EXISTENCE:direct assay:GO:1990841 promoter-specific chromatin binding [PMID:27184763]
experiment: EXISTENCE:mutant phenotype:GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport [PMID:10532354]
experiment: EXISTENCE:mutant phenotype:GO:0006901 vesicle coating [PMID:9463377]
experiment: EXISTENCE:mutant phenotype:GO:0030126 COPI vesicle coat [PMID:9463377]
experiment: EXISTENCE:mutant phenotype:GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway [PMID:17101773]
experiment: EXISTENCE:physical interaction:GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway [PMID:17101773]
note: Epsilon-COP subunit of the coatomer; regulates retrograde Golgi-to-ER protein traffic; stabilizes Cop1p, the alpha-COP and the coatomer complex; non-essential for cell growth; protein abundance increases in response to DNA replication stress
codon start: 1
product: coatomer subunit epsilon
translation: MDYFNIKQNYYTGNFVQCLQEIEKFSKVTDNTLLFYKAKTLLALGQYQSQDPTSKLGKVLDLYVQFLDTKNIEELENLLKDKQNSPYELYLLATAQAILGDLDKSLETCVEGIDNDEAEGTTELLLLAIEVALLNNNVSTASTIFDNYTNAIEDTVSGDNEMILNLAESYIKFATNKETATSNFYYYEELSQTFPTWKTQLGLLNLHLQQRNIAEAQGIVELLLSDYYSVEQKENAVLYKPTFLANQITLALMQGLDTEDLTNQLVKLDHEHAFIKHHQEIDAKFDELVRKYDTSN
SIO_010081: YIL076W
subclass of: SO_0000673
so part of: YIL076W
location: 216658..217548
location: region:216658-217548:1
so has part: feature:216658-217548:1:exon

NP_012189.2
type: Protein
SIO_000068: ncbiprotein

S000001338
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:216658-217548:1:exon

YIL075C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SEN3
gene: RPN2
locus tag: YIL075C
gene synonym: SEN3
so part of: sequence
location: complement(<217863..>220700)
location: region:217863-220700:-1
so has part: feature:217863-220700:-1:exon
subclass of: SO_0000010

854735
type: Gene
SIO_000068: ncbigene

position:217863:-1
position: 217863
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:220700:-1
position: 220700
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:217863-220700:-1:exon

YIL075C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SEN3
gene: RPN2
locus tag: YIL075C
gene synonym: SEN3
product: proteasome regulatory particle base subunit RPN2
transcript id: NM_001179425.1
SIO_010081: YIL075C
subclass of: SO_0000673
so part of: YIL075C
location: complement(<217863..>220700)
location: region:217863-220700:-1
so has part: feature:217863-220700:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:217863-220700:-1:exon

YIL075C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SEN3
gene: RPN2
locus tag: YIL075C
gene synonym: SEN3
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:15210724|PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0008540 proteasome regulatory particle, base subcomplex [PMID:9741626]
experiment: EXISTENCE:direct assay:GO:0034515 proteasome storage granule [PMID:18504300]
experiment: EXISTENCE:genetic interaction:GO:0043248 proteasome assembly [PMID:17911101]
experiment: EXISTENCE:mutant phenotype:GO:0004175 endopeptidase activity [PMID:7565784]
experiment: EXISTENCE:mutant phenotype:GO:0006511 ubiquitin-dependent protein catabolic process [PMID:7565784]
experiment: EXISTENCE:physical interaction:GO:0031625 ubiquitin protein ligase binding [PMID:10688918]
note: Subunit of the 26S proteasome; substrate of the N-acetyltransferase Nat1p; protein abundance increases in response to DNA replication stress
codon start: 1
product: proteasome regulatory particle base subunit RPN2
translation: MSLTTAAPLLALLRENQDSVKTYALESINNVVDQLWSEISNELPDIEALYDDDTFSDREMAALIASKVYYNLGEYESAVKYALAAKDRFDIDEKSQFVETIVSKSIEMYVQEASKQYTKDEQFYTKDIIDPKLTSIFERMIEKCLKASELKLALGIALEGYRLDIIESALKSKLDQDSTSENVKIINYLLTLAITTVTNSKFRSSILRKSFDFLMNMPNCDYLTLNKVVVNLNDAGLALQLFKKLKEENDEGLSAQIAFDLVSSASQQLLEILVTELTAQGYDPALLNILSGLPTCDYYNTFLLNNKNIDIGLLNKSKSSLDGKFSLFHTAVSVANGFMHAGTTDNSFIKANLPWLGKAQNWAKFTATASLGVIHKGNLLEGKKVMAPYLPGSRASSRFIKGGSLYGLGLIYAGFGRDTTDYLKNIIVENSGTSGDEDVDVLLHGASLGIGLAAMGSANIEVYEALKEVLYNDSATSGEAAALGMGLCMLGTGKPEAIHDMFTYSQETQHGNITRGLAVGLALINYGRQELADDLITKMLASDESLLRYGGAFTIALAYAGTGNNSAVKRLLHVAVSDSNDDVRRAAVIALGFVLLRDYTTVPRIVQLLSKSHNAHVRCGTAFALGIACAGKGLQSAIDVLDPLTKDPVDFVRQAAMIALSMILIQQTEKLNPQVADINKNFLSVITNKHQEGLAKFGACVAQGIMNAGGRNVTIQLENADTGTLDTKSVVGLVMFSQFWYWFPLAHFLSLSFTPTTVIGIRGSDQAIPKFQMNCYAKEDAFSYPRMYEEASGKEVEKVATAVLSTTARAKARAKKTKKEKGPNEEEKKKEHEEKEKERETNKKGIKETKENDEEFYKNKYSSKPYKVDNMTRILPQQSRYISFIKDDRFVPVRKFKGNNGVVVLRDREPKEPVALIETVRQMKDVNAPLPTPFKVDDNVDFPSA
SIO_010081: YIL075C
subclass of: SO_0000673
so part of: YIL075C
location: complement(217863..220700)
location: region:217863-220700:-1
so has part: feature:217863-220700:-1:exon

NP_012190.1
type: Protein
SIO_000068: ncbiprotein

S000001337
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:217863-220700:-1:exon

YIL074C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SER33
locus tag: YIL074C
so part of: sequence
location: complement(<221081..>222490)
location: region:221081-222490:-1
so has part: feature:221081-222490:-1:exon
subclass of: SO_0000010

854736
type: Gene
SIO_000068: ncbigene

position:221081:-1
position: 221081
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:222490:-1
position: 222490
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:221081-222490:-1:exon

YIL074C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SER33
locus tag: YIL074C
product: phosphoglycerate dehydrogenase SER33
transcript id: NM_001179424.1
SIO_010081: YIL074C
subclass of: SO_0000673
so part of: YIL074C
location: complement(<221081..>222490)
location: region:221081-222490:-1
so has part: feature:221081-222490:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:221081-222490:-1:exon

YIL074C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SER33
locus tag: YIL074C
EC number: 1.1.1.95
EC number: 1.1.1.399
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0061759 alpha-ketoglutarate reductase activity [PMID:26774271]
experiment: EXISTENCE:genetic interaction:GO:0061759 alpha-ketoglutarate reductase activity [PMID:26774271]
experiment: EXISTENCE:mutant phenotype:GO:0004617 phosphoglycerate dehydrogenase activity [PMID:12525494]
experiment: EXISTENCE:mutant phenotype:GO:0009070 serine family amino acid biosynthetic process [PMID:12525494]
experiment: EXISTENCE:mutant phenotype:GO:0061759 alpha-ketoglutarate reductase activity [PMID:26774271]
note: 3-phosphoglycerate dehydrogenase and alpha-ketoglutarate reductase; 3PG dehydrogenase that catalyzes the first step in serine and glycine biosynthesis; also functions as an alpha-ketoglutarate reductase, converting alpha-ketoglutarate to D-2-hydroxyglutarate (D-2HG); localizes to the cytoplasm; SER33 has a paralog, SER3, that arose from the whole genome duplication
codon start: 1
product: phosphoglycerate dehydrogenase SER33
translation: MSYSAADNLQDSFQRAMNFSGSPGAVSTSPTQSFMNTLPRRVSITKQPKALKPFSTGDMNILLLENVNATAIKIFKDQGYQVEFHKSSLPEDELIEKIKDVHAIGIRSKTRLTEKILQHARNLVCIGCFCIGTNQVDLKYAASKGIAVFNSPFSNSRSVAELVIGEIISLARQLGDRSIELHTGTWNKVAARCWEVRGKTLGIIGYGHIGSQLSVLAEAMGLHVLYYDIVTIMALGTARQVSTLDELLNKSDFVTLHVPATPETEKMLSAPQFAAMKDGAYVINASRGTVVDIPSLIQAVKANKIAGAALDVYPHEPAKNGEGSFNDELNSWTSELVSLPNIILTPHIGGSTEEAQSSIGIEVATALSKYINEGNSVGSVNFPEVSLKSLDYDQENTVRVLYIHRNVPGVLKTVNDILSDHNIEKQFSDSHGEIAYLMADISSVNQSEIKDIYEKLNQTSAKVSIRLLY
SIO_010081: YIL074C
subclass of: SO_0000673
so part of: YIL074C
location: complement(221081..222490)
location: region:221081-222490:-1
so has part: feature:221081-222490:-1:exon

NP_012191.1
type: Protein
SIO_000068: ncbiprotein

S000001336
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:221081-222490:-1:exon

YIL073C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ZIP4
gene: SPO22
locus tag: YIL073C
gene synonym: ZIP4
so part of: sequence
location: complement(<222937..>225954)
location: region:222937-225954:-1
so has part: feature:222937-225954:-1:exon
subclass of: SO_0000010

854737
type: Gene
SIO_000068: ncbigene

position:222937:-1
position: 222937
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:225954:-1
position: 225954
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:222937-225954:-1:exon

YIL073C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ZIP4
gene: SPO22
locus tag: YIL073C
gene synonym: ZIP4
product: Spo22p
transcript id: NM_001179423.1
SIO_010081: YIL073C
subclass of: SO_0000673
so part of: YIL073C
location: complement(join(<222937..225809,225900..>225954))
location: region:222937-225954:-1
so has part: feature:225900-225954:-1:exon
so has part: feature:222937-225809:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:225900-225954:-1:exon

position:225900:-1
position: 225900
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:222937-225809:-1:exon

position:225809:-1
position: 225809
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YIL073C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ZIP4
gene: SPO22
locus tag: YIL073C
gene synonym: ZIP4
experiment: EXISTENCE:direct assay:GO:0000794 condensed nuclear chromosome [PMID:16740482]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:24390141]
experiment: EXISTENCE:mutant phenotype:GO:0033235 positive regulation of protein sumoylation [PMID:23326245]
experiment: EXISTENCE:mutant phenotype:GO:0090173 regulation of synaptonemal complex assembly [PMID:16740482]
note: Meiosis-specific protein essential for chromosome synapsis; involved in completion of nuclear divisions during meiosis; induced early in meiosis
codon start: 1
product: Spo22p
translation: MSDHNVNSTFRKTLVELCETATWITSQVYAAKNLEKNDLITVDNKISALYPIAEKYDRSFRTTTVILDEELILKLENAASSLWNSLTIAMKAEKASDKYFNEVFCKCKIFATKLLSIHEALFRTNTNLLRNFKCYISSFKSASEYRFDDLITNTQQHSEKYLQIINENVESFSNEEKTEFKKLTFEFYLVNFQLYLSENDLDTANIYTAKVNITDNSKYMDADLLIELCRMIYNSTVMLKEINNPETQLVDVNIISFLKDVEKYLELPVENLKSHTDYSNLKYSVLIFMANCLVEGHPQASELEQCDHYLSLLQNEYPNKVDPFILAINLTKRRNIVNPAETIEEILMRMIMSVDVISNFQAVIASINDLSKMNTKFSIVCLDYLLINKLNSKNDSKFLGKAICSRFLITTQSKTMNDSEIAESLENFSTQMERIVSEPLTKHAISCIITLLWNTGKKLEKMEKYVVSIRFYKLALKDIISQNYSDRGKIQRALQVVYNKIEDYSNTVRVYQDMDEVDRQSPLCQLLMLQSFLADDKTEEALTCLQKIKSSEDEKSTDALILAVAECKRKTDLSVQGLLMIFDKLQSKSNSQTISSTSSSQTLSILRYTLQMIVKVSEEEPLETFINYLPTVQKLLQKAVEFLKTVKLLNQLPPDVEKEAIYQQSVAVNEIEWFASFSYNVAVKCLVDQSCESISEFPQYCIQFIDLIPVQDFTFPKMYHFTYWRFKATILQLIIAKEKAKQDQHQKDWDIYEKSEELVNSINVMKKSSEFKDGSSLEDRNTLHECFLEALTIHLESALMMPDQTRILDILKKTELYQDSRVDALLIDISSNMEDLPKGVLIEILETVLKRNMGPEVKERELCSWLRILLENAINLNHEVELRILDRVLKILNINQSSLQDTDGVLQTELETIATYCWNIGVNYIIKDNKSNGIVWCKHSMGFANMVNEGLQEQLYSLWESLASSANIDINSIAK
SIO_010081: YIL073C
subclass of: SO_0000673
so part of: YIL073C
location: complement(join(222937..225809,225900..225954))
location: region:222937-225954:-1
so has part: feature:225900-225954:-1:exon
so has part: feature:222937-225809:-1:exon

NP_012192.2
type: Protein
SIO_000068: ncbiprotein

S000001335
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:225900-225954:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:222937-225809:-1:exon

YIL072W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HOP1
locus tag: YIL072W
so part of: sequence
location: <226602..>228419
location: region:226602-228419:1
so has part: feature:226602-228419:1:exon
subclass of: SO_0000010

854738
type: Gene
SIO_000068: ncbigene

position:226602:1
position: 226602
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:228419:1
position: 228419
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:226602-228419:1:exon

YIL072W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HOP1
locus tag: YIL072W
product: Hop1p
transcript id: NM_001179422.3
SIO_010081: YIL072W
subclass of: SO_0000673
so part of: YIL072W
location: <226602..>228419
location: region:226602-228419:1
so has part: feature:226602-228419:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:226602-228419:1:exon

YIL072W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: HOP1
locus tag: YIL072W
experiment: EXISTENCE:direct assay:GO:0000400 four-way junction DNA binding [PMID:17027027]
experiment: EXISTENCE:direct assay:GO:0000794 condensed nuclear chromosome [PMID:2107981]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:23841450|PMID:24390141]
experiment: EXISTENCE:genetic interaction:GO:0051598 meiotic recombination checkpoint signaling [PMID:10848609]
experiment: EXISTENCE:mutant phenotype:GO:0007129 homologous chromosome pairing at meiosis [PMID:2107981|PMID:8207053]
experiment: EXISTENCE:mutant phenotype:GO:0007130 synaptonemal complex assembly [PMID:2653960]
experiment: EXISTENCE:physical interaction:GO:0000800 lateral element [PMID:9060462]
note: Meiosis-specific protein required for chromosome synapsis; displays Red1p dependent localization to the unsynapsed axial-lateral elements of the synaptonemal complex; required for chiasma formation; in vitro, displays the ability to promote intra- and intermolecular synapsis between double-stranded DNA molecules and to fold DNA into rigid protein-DNA filaments
codon start: 1
product: Hop1p
translation: MSNKQLVKPKTETKTEITTEQSQKLLQTMLTMSFGCLAFLRGLFPDDIFVDQRFVPEKVEKNYNKQNTSQNNSIKIKTLIRGKSAQADLLLDWLEKGVFKSIRLKCLKALSLGIFLEDPTDLLENYIFSFDYDEENNVNINVNLSGNKKGSKNADPENETISLLDSRRMVQQLMRRFIIITQSLEPLPQKKFLTMRLMFNDNVDEDYQPELFKDATFDKRATLKVPTNLDNDAIDVGTLNTKHHKVALSVLSAATSSMEKAGNTNFIRVDPFDLILQQQEENKLEESVPTKPQNFVTSQTTNVLGNLLNSSQASIQPTQFVSNNPVTGICSCECGLEVPKAATVLKTCKSCRKTLHGICYGNFLHSSIEKCFTCIFGPSLDTKWSKFQDLMMIRKVFRFLVRKKKGFPASITELIDSFINVEDQNNEVKERVAFALFVFFLDETLCLDNGGKPSQTIRYVTSSVLVDVKGIVIPNTRKQLNVNHEYKWHFTTSSPKAESFYQEVLPNSRKQVESWLQDITNLRKVYSEALSPSSTLQELDLNSSLPTQDPIISGQKRRRYDLDEYLEEDKSSVVNDTIKAKDFDESVPAKIRKISVSKKTLKSNW
SIO_010081: YIL072W
subclass of: SO_0000673
so part of: YIL072W
location: 226602..228419
location: region:226602-228419:1
so has part: feature:226602-228419:1:exon

NP_012193.3
type: Protein
SIO_000068: ncbiprotein

S000001334
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:226602-228419:1:exon

YIL071C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CSN11
alternative label: YIH1
alternative label: YIL071W
gene: PCI8
locus tag: YIL071C
gene synonym: CSN11; YIH1; YIL071W
so part of: sequence
location: complement(<228660..>229994)
location: region:228660-229994:-1
so has part: feature:228660-229994:-1:exon
subclass of: SO_0000010

854739
type: Gene
SIO_000068: ncbigene

position:228660:-1
position: 228660
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:229994:-1
position: 229994
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:228660-229994:-1:exon

YIL071C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CSN11
alternative label: YIH1
alternative label: YIL071W
gene: PCI8
locus tag: YIL071C
gene synonym: CSN11; YIH1; YIL071W
product: Pci8p
transcript id: NM_001179421.3
SIO_010081: YIL071C
subclass of: SO_0000673
so part of: YIL071C
location: complement(<228660..>229994)
location: region:228660-229994:-1
so has part: feature:228660-229994:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:228660-229994:-1:exon

YIL071C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CSN11
alternative label: YIH1
alternative label: YIL071W
gene: PCI8
locus tag: YIL071C
gene synonym: CSN11; YIH1; YIL071W
experiment: EXISTENCE:direct assay:GO:0008180 COP9 signalosome [PMID:12446563]
experiment: EXISTENCE:mutant phenotype:GO:0000338 protein deneddylation [PMID:12186635|PMID:12446563]
note: Possible shared subunit of Cop9 signalosome (CSN) and eIF3; binds eIF3b subunit Prt1p, has possible dual functions in transcriptional and translational control, contains a PCI (Proteasome-COP9 signalosome (CSN)-eIF3) domain
codon start: 1
product: Pci8p
translation: MFHGAKGPLLIERIGHLLSINYGEKEERKRWAMQGISYLQEVQCTSTPYLEILVEESGLRPVSLLNSQLVGKPHFSLLGGFDENIARDIISHNFQNAIFQMESEEVPLTKRYQHLEKITQISLLCKNFKGIEEIEYNVKNIIQGRKNFDMLNSMEKDRISHEVVQDDSFSLLRIQMLLCVSYFLQERYFDCCTKFFTMMTSEPLTLKVLSEHLDCMNFISKEEFIMMVNISVLISIPLDNYDDFIYLSDLKQFFQMTPLLVNCLELLINTNFNKFFKIWHGEINKICMESLFLEPSWSSSAAVIMRCKIYFFYLRISKKLQFSYLSSTLGIDLEDIKEELTKLIISGQLNFEIDGDVIHFEDSSILQSIVNEISRNGTMINEVIDKLKNENTDLKDIIQGNPLMYSGGNNTATIINNESSDDMDIDEVNDRSDISDSEGGLFEC
SIO_010081: YIL071C
subclass of: SO_0000673
so part of: YIL071C
location: complement(228660..229994)
location: region:228660-229994:-1
so has part: feature:228660-229994:-1:exon

NP_085069.3
type: Protein
SIO_000068: ncbiprotein

S000001333
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:228660-229994:-1:exon

YIL070C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MAM33
locus tag: YIL070C
so part of: sequence
location: complement(<230272..>231072)
location: region:230272-231072:-1
so has part: feature:230272-231072:-1:exon
subclass of: SO_0000010

854740
type: Gene
SIO_000068: ncbigene

position:230272:-1
position: 230272
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:231072:-1
position: 231072
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:230272-231072:-1:exon

YIL070C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MAM33
locus tag: YIL070C
product: Mam33p
transcript id: NM_001179420.1
SIO_010081: YIL070C
subclass of: SO_0000673
so part of: YIL070C
location: complement(<230272..>231072)
location: region:230272-231072:-1
so has part: feature:230272-231072:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:230272-231072:-1:exon

YIL070C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MAM33
locus tag: YIL070C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005759 mitochondrial matrix [PMID:9305894]
experiment: EXISTENCE:direct assay:GO:0097177 mitochondrial ribosome binding [PMID:31053642]
experiment: EXISTENCE:mutant phenotype:GO:0009060 aerobic respiration [PMID:9305894]
experiment: EXISTENCE:mutant phenotype:GO:0061668 mitochondrial ribosome assembly [PMID:31053642]
note: Acidic protein of the mitochondrial matrix; binds unassembled large subunit proteins during ribosome assembly; subunit of a complex containing Mrx6p, Pim1p, and Pet20p that may regulate mtDNA replication; related to the human complement receptor gC1q-R
codon start: 1
product: Mam33p
translation: MFLRSVNRAVTRSILTTPKPAVVKSSWRVFTVANSKRCFTPAAIMRNQETQRVGDILQSELKIEKETLPESTSLDSFNDFLNKYKFSLVETPGKNEAEIVRRTESGETVHVFFDVAQIANLPYNNAMDENTEQNEDGINEDDFDALSDNFANVNVVISKESASEPAVSFELLMNLQEGSFYVDSATPYPSVDAALNQSAEAEITRELVYHGPPFSNLDEELQESLEAYLESRGVNEELASFISAYSEFKENNEYISWLEKMKKFFH
SIO_010081: YIL070C
subclass of: SO_0000673
so part of: YIL070C
location: complement(230272..231072)
location: region:230272-231072:-1
so has part: feature:230272-231072:-1:exon

NP_012194.1
type: Protein
SIO_000068: ncbiprotein

S000001332
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:230272-231072:-1:exon

YIL069C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RPS24EB
gene: RPS24B
locus tag: YIL069C
gene synonym: RPS24EB
so part of: sequence
location: complement(<231553..>232369)
location: region:231553-232369:-1
so has part: feature:231553-232369:-1:exon
subclass of: SO_0000010

854741
type: Gene
SIO_000068: ncbigene

position:231553:-1
position: 231553
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:232369:-1
position: 232369
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:231553-232369:-1:exon

YIL069C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RPS24EB
gene: RPS24B
locus tag: YIL069C
gene synonym: RPS24EB
product: ribosomal 40S subunit protein S24B
transcript id: NM_001179419.1
SIO_010081: YIL069C
subclass of: SO_0000673
so part of: YIL069C
location: complement(join(<231553..231957,232367..>232369))
location: region:231553-232369:-1
so has part: feature:232367-232369:-1:exon
so has part: feature:231553-231957:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:232367-232369:-1:exon

position:232367:-1
position: 232367
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:231553-231957:-1:exon

position:231957:-1
position: 231957
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YIL069C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RPS24EB
gene: RPS24B
locus tag: YIL069C
gene synonym: RPS24EB
experiment: EXISTENCE:genetic interaction:GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:16246728]
note: Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S24, no bacterial homolog; RPS24B has a paralog, RPS24A, that arose from the whole genome duplication
codon start: 1
product: ribosomal 40S subunit protein S24B
translation: MSDAVTIRTRKVISNPLLARKQFVVDVLHPNRANVSKDELREKLAEVYKAEKDAVSVFGFRTQFGGGKSVGFGLVYNSVAEAKKFEPTYRLVRYGLAEKVEKASRQQRKQKKNRDKKIFGTGKRLAKKVARRNAD
SIO_010081: YIL069C
subclass of: SO_0000673
so part of: YIL069C
location: complement(join(231553..231957,232367..232369))
location: region:231553-232369:-1
so has part: feature:232367-232369:-1:exon
so has part: feature:231553-231957:-1:exon

NP_012195.1
type: Protein
SIO_000068: ncbiprotein

S000001331
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:232367-232369:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:231553-231957:-1:exon

YIL068C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SEC6
locus tag: YIL068C
so part of: sequence
location: complement(<233057..>235474)
location: region:233057-235474:-1
so has part: feature:233057-235474:-1:exon
subclass of: SO_0000010

854742
type: Gene
SIO_000068: ncbigene

position:233057:-1
position: 233057
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:235474:-1
position: 235474
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:233057-235474:-1:exon

YIL068C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SEC6
locus tag: YIL068C
product: SNARE-binding exocyst subunit SEC6
transcript id: NM_001179418.1
SIO_010081: YIL068C
subclass of: SO_0000673
so part of: YIL068C
location: complement(<233057..>235474)
location: region:233057-235474:-1
so has part: feature:233057-235474:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:233057-235474:-1:exon

YIL068C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SEC6
locus tag: YIL068C
experiment: EXISTENCE:direct assay:GO:0000145 exocyst [PMID:7615633|PMID:8978675]
experiment: EXISTENCE:direct assay:GO:0000149 SNARE binding [PMID:15835919|PMID:22114349]
experiment: EXISTENCE:direct assay:GO:0005628 prospore membrane [PMID:24390141]
experiment: EXISTENCE:direct assay:GO:0005934 cellular bud tip [PMID:19073882]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:19073882|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0035544 negative regulation of SNARE complex assembly [PMID:15835919|PMID:22114349]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:19053807]
experiment: EXISTENCE:genetic interaction:GO:0006893 Golgi to plasma membrane transport [PMID:7026045]
experiment: EXISTENCE:genetic interaction:GO:0035544 negative regulation of SNARE complex assembly [PMID:22114349]
experiment: EXISTENCE:mutant phenotype:GO:0006887 exocytosis [PMID:6996832]
experiment: EXISTENCE:mutant phenotype:GO:0006893 Golgi to plasma membrane transport [PMID:7026045]
experiment: EXISTENCE:mutant phenotype:GO:0051601 exocyst localization [PMID:19073882]
experiment: EXISTENCE:physical interaction:GO:0000149 SNARE binding [PMID:15835919|PMID:22114349]
experiment: EXISTENCE:physical interaction:GO:0035544 negative regulation of SNARE complex assembly [PMID:15835919|PMID:22114349]
note: Essential 88kDa subunit of the exocyst complex; the exocyst mediates polarized targeting and tethering of post-Golgi secretory vesicles to active sites of exocytosis at the plasma membrane prior to SNARE-mediated fusion; anchors the assembled complex to sites of secretion; interacts with SM-like protein and SNARE regulator Sec1p and may recruit it to sites of secretion; binds to SNARE complexes binteracting with Sec9p
codon start: 1
product: SNARE-binding exocyst subunit SEC6
translation: MSSDPLQQVCDLIKGDLSLERVRDIKEQLLKEKSVVEYQLNKESDKYYGEVEESLKLLNLSKNSVTSIKQQINEVNKLGNDNRFAINRYDILFRATKLYETVNTTSSIYDRIYNFVALMEHIERLLVAELAEDALETGCPHLLEIHFLLTSARDFQEQVVVMAKEATEDAQRTVMKLFSRLSGIISKFDKLLDGLTYDIVEMARAEQISLAIRLFKIYDLEEREDLRIEAIRNIIKKKEIEIEKSSIKKLPNSKNTARLQDETPKVIEYPTNKGLYQEIMSGTISTRTAPRGYKHFLINGINNSISEMFGEMREKYVGDQKFDVLDNMDWIFNELIIVKEHIANCCPPHWNIFEVYFDQYYKELHSLITDLVESEPETIIILDILAFDKTFQDTLKQDFGFTKSEVKSVIGDKEKETLFKDYLNLIVVKMTEWIGNLEKAEFDVFLERSTPPHSDSDGLLFLDGTKTCFQMFTQQVEVAAGTNQAKILVGVVERFSDLLTKRQKNWISKISEEIKKQINYNHKYDIDPESITPEDECPGGLVEYLIAVSNDQMKAADYAVAISSKYGKLVSKVYEKQITNHLEGTLDGFAEVAQCSSLGLITLMFDDLRKPYQEIFSKTWYMGSQAQQIADTLDEYLLDIKPQMNSVLFVNFIDNVIGETIIKFLTALSFEHSFKNKNNKFLEAMKRDFEIFYQLFVKVLDGNESKDTLITQNFTVMEFFMDLSCEPIDSILDIWQKYLEVYWDSRIDLLVGILKCRKDVSSSERKKIVQQATEMLHEYRRNMEANGVDREPTLMRRFVLEFEKQ
SIO_010081: YIL068C
subclass of: SO_0000673
so part of: YIL068C
location: complement(233057..235474)
location: region:233057-235474:-1
so has part: feature:233057-235474:-1:exon

NP_012196.1
type: Protein
SIO_000068: ncbiprotein

S000001330
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:233057-235474:-1:exon

YIL067C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YIL067C
so part of: sequence
location: complement(<235724..>237760)
location: region:235724-237760:-1
so has part: feature:235724-237760:-1:exon
subclass of: SO_0000010

854743
type: Gene
SIO_000068: ncbigene

position:235724:-1
position: 235724
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:237760:-1
position: 237760
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:235724-237760:-1:exon

YIL067C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YIL067C
product: uncharacterized protein
transcript id: NM_001179417.1
SIO_010081: YIL067C
subclass of: SO_0000673
so part of: YIL067C
location: complement(<235724..>237760)
location: region:235724-237760:-1
so has part: feature:235724-237760:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:235724-237760:-1:exon

YIL067C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YIL067C
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:14562095]
note: Uncharacterized hypothetical protein
codon start: 1
product: uncharacterized protein
translation: MGVHFDDNANTTWEATDPGVSSDCDGQHRVTESIQLQNFSNTDMESMLDEEGRENSKSKWLLLKRKHPIQKFIERVWNGPVEPSDEPPSFPKRWGWLKKIDDFPQTTFKTKIPSKLIRLLLLIVYCCFWMRIFYSLIYPYLIKPPYFHPNDGSEKIPILSLSCNSYLNWEGTNNECGLNAKNCGPLDNKEYMIRCPALCDRGGWTYSAIAVGNRRVKYTGYEIGGGALFSEEDPMVVSYPYRSDSFPCASAVHAGVISPFYGGCTKVSMQGAQNSFPSKKGMYNTGFSVAFNSFFPGSYSFRDIQGGILSGCYDPRAAVVALNMLFGLPIFYLYDSIYGYWINTIVGYWTLVLSLDPPLLTDAHDPASVYELFSVGFQRLLPLCFVLYVVWKSAVKRTLENGSPIAKVILWYPTFWLGISNNVTFDRLPVDRLTTTDLKEQAGALTAVGSIAATILTCAVIQAYSLWKSGRFKKYFKIYICFIGGLIALGSLPGLNLRIHHYILGSILVPGCATRGSSAYLFQGILVGLILSGVARWDFASIVETDTALLRGEAGASLKPPILDFNDDQNHSLSWHLNATDPVIDQIGNIDGFSLLLNDVEVYVGKNETVSIDVLRMENPALAQMMDDALDASNGTIDLYLRVARASVRSPTNRGDYTNAGVLQWPNGMWQKPEPGVS
SIO_010081: YIL067C
subclass of: SO_0000673
so part of: YIL067C
location: complement(235724..237760)
location: region:235724-237760:-1
so has part: feature:235724-237760:-1:exon

NP_012197.1
type: Protein
SIO_000068: ncbiprotein

S000001329
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:235724-237760:-1:exon

YIL066C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: DIN1
alternative label: RIR3
gene: RNR3
locus tag: YIL066C
gene synonym: DIN1; RIR3
so part of: sequence
location: complement(<238099..>240708)
location: region:238099-240708:-1
so has part: feature:238099-240708:-1:exon
subclass of: SO_0000010

854744
type: Gene
SIO_000068: ncbigene

position:238099:-1
position: 238099
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:240708:-1
position: 240708
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:238099-240708:-1:exon

YIL066C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: DIN1
alternative label: RIR3
gene: RNR3
locus tag: YIL066C
gene synonym: DIN1; RIR3
product: ribonucleotide-diphosphate reductase subunit RNR3
transcript id: NM_001179416.3
SIO_010081: YIL066C
subclass of: SO_0000673
so part of: YIL066C
location: complement(<238099..>240708)
location: region:238099-240708:-1
so has part: feature:238099-240708:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:238099-240708:-1:exon

YIL066C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: DIN1
alternative label: RIR3
gene: RNR3
locus tag: YIL066C
gene synonym: DIN1; RIR3
EC number: 1.17.4.1
experiment: EXISTENCE:direct assay:GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [PMID:11893751]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:12732713]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:14576278]
experiment: EXISTENCE:direct assay:GO:0009263 deoxyribonucleotide biosynthetic process [PMID:5459124]
note: Minor isoform of large subunit of ribonucleotide-diphosphate reductase; the RNR complex catalyzes rate-limiting step in dNTP synthesis, regulated by DNA replication and DNA damage checkpoint pathways via localization of small subunits; RNR3 has a paralog, RNR1, that arose from the whole genome duplication
codon start: 1
product: ribonucleotide-diphosphate reductase subunit RNR3
translation: MYVIKRDGRKEPVQFDKITSRITRLSYGLDPNRIDAVKVTQRIISGVYSGVTTVELDNLAAETCAYMTTVHPDYATLAARIAISNLHKQTTKQFSKVIEDLHDWINPATGKHAPMISDEIYNIVMENKDTLNSAIVYDRDFQYTYFGFKTLERSYLLRLNGEVAERPQHLVMRVALGIHGSDIESVLKTYNLMSLRYFTHASPTLFNAGTPHPQMSSCFLIAMKDDSIEGIYDTLKECAMISKTAGGVGLHINNIRSTGSYIAGTNGTSNGLIPMIRVFNNTARYVDQGGNKRPGAFALFLEPWHADIFDFVDIRKTHGKEEIRARDLFPALWIPDLFMKRVQEDGPWTLFSPSAAPGLDDVWGDEFEELYTRYEREGRGKTIKAQKLWYAILQAQTETGTPFMVYKDACNRKTNQQNLGTIKSSNLCCEIVEYSSPDETAVCNLASIALPAFVEVSEDGKTASYNFERLHEIAKVITHNLNRVIDRNYYPVPEARNSNMKHRPIALGVQGLADTYMMLRLPFESEEAQTLNKQIFETIYHATLEASCELAQKEGKYSTFEGSPASKGILQFDMWNAKPFGMWDWETLRKDIVKHGLRNSLTMAPMPTASTSQILGYNECFEPVTSNMYSRRVLSGEFQVVNPYLLRDLVDLGIWDDSMKQYLITQNGSIQGLPNVPQELKELYKTVWEISQKTIINMAADRAIYIDQSHSLNLFLQAPSMGKITSMHFYGWKKGLKTGMYYLRTQAASAAIQFTIDQEVADQAATHIASVSELDRPVYVPKGTKFSEQKAASALTESSDNEKDASPVPSEQSSVSSAMSNVKLEDSVAPAVPTETIKEDSDEKKCDIYNEKVIACTAPTPEACESCSG
SIO_010081: YIL066C
subclass of: SO_0000673
so part of: YIL066C
location: complement(238099..240708)
location: region:238099-240708:-1
so has part: feature:238099-240708:-1:exon

NP_012198.3
type: Protein
SIO_000068: ncbiprotein

S000001328
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:238099-240708:-1:exon

YIL065C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MDV2
gene: FIS1
locus tag: YIL065C
gene synonym: MDV2
so part of: sequence
location: complement(<241308..>241775)
location: region:241308-241775:-1
so has part: feature:241308-241775:-1:exon
subclass of: SO_0000010

854745
type: Gene
SIO_000068: ncbigene

position:241308:-1
position: 241308
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:241775:-1
position: 241775
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:241308-241775:-1:exon

YIL065C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MDV2
gene: FIS1
locus tag: YIL065C
gene synonym: MDV2
product: Fis1p
transcript id: NM_001179415.3
SIO_010081: YIL065C
subclass of: SO_0000673
so part of: YIL065C
location: complement(<241308..>241775)
location: region:241308-241775:-1
so has part: feature:241308-241775:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:241308-241775:-1:exon

YIL065C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MDV2
gene: FIS1
locus tag: YIL065C
gene synonym: MDV2
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005741 mitochondrial outer membrane [PMID:11038183|PMID:15809300|PMID:16407407]
experiment: EXISTENCE:direct assay:GO:0005777 peroxisome [PMID:16968746]
experiment: EXISTENCE:genetic interaction:GO:0016559 peroxisome fission [PMID:18445678]
experiment: EXISTENCE:mutant phenotype:GO:0000266 mitochondrial fission [PMID:11038182|PMID:11038183]
experiment: EXISTENCE:mutant phenotype:GO:0007031 peroxisome organization [PMID:16968746]
note: Protein involved in mitochondrial fission and peroxisome abundance; may have a distinct role in tethering protein aggregates to mitochondria in order to retain them in the mother cell; required for localization of Dnm1p and Mdv1p during mitochondrial division; mediates ethanol-induced apoptosis and ethanol-induced mitochondrial fragmentation
codon start: 1
product: Fis1p
translation: MTKVDFWPTLKDAYEPLYPQQLEILRQQVVSEGGPTATIQSRFNYAWGLIKSTDVNDERLGVKILTDIYKEAESRRRECLYYLTIGCYKLGEYSMAKRYVDTLFEHERNNKQVGALKSMVEDKIQKETLKGVVVAGGVLAGAVAVASFFLRNKRR
SIO_010081: YIL065C
subclass of: SO_0000673
so part of: YIL065C
location: complement(241308..241775)
location: region:241308-241775:-1
so has part: feature:241308-241775:-1:exon

NP_012199.3
type: Protein
SIO_000068: ncbiprotein

S000001327
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:241308-241775:-1:exon

YIL064W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SEE1
gene: EFM4
locus tag: YIL064W
gene synonym: SEE1
so part of: sequence
location: <241943..>242716
location: region:241943-242716:1
so has part: feature:241943-242716:1:exon
subclass of: SO_0000010

854746
type: Gene
SIO_000068: ncbigene

position:241943:1
position: 241943
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:242716:1
position: 242716
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:241943-242716:1:exon

YIL064W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SEE1
gene: EFM4
locus tag: YIL064W
gene synonym: SEE1
product: Efm4p
transcript id: NM_001179414.1
SIO_010081: YIL064W
subclass of: SO_0000673
so part of: YIL064W
location: <241943..>242716
location: region:241943-242716:1
so has part: feature:241943-242716:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:241943-242716:1:exon

YIL064W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SEE1
gene: EFM4
locus tag: YIL064W
gene synonym: SEE1
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0016279 protein-lysine N-methyltransferase activity [PMID:20510667]
experiment: EXISTENCE:mutant phenotype:GO:0016192 vesicle-mediated transport [PMID:19160456]
note: Lysine methyltransferase; involved in the dimethylation of eEF1A (Tef1p/Tef2p) at lysine 316; sequence similarity to S-adenosylmethionine-dependent methyltransferases of the seven beta-strand family; role in vesicular transport
codon start: 1
product: Efm4p
translation: MKRSEKKSMSSALKNGIMERTQPEKVVQMQGTADLSTSKLGTKKYWDELYALELENFRRNPQDTGDCWFSDSDAEQKMIDFLVDNIGAYRISENASVVDLGTGNGHMLFELHQTEFQGKLVGIDYSEESVKLASNIAEATGVDNFISFQQADIFSGDWKPGKYDIVLDKGTLDAISLSGMKINGKLDVVDVYAGVVERILKKDGIFLITSCNFTQDELVKIIETDNLKMWKTIKYPVFQFGGVQGATICSVAFVKQN
SIO_010081: YIL064W
subclass of: SO_0000673
so part of: YIL064W
location: 241943..242716
location: region:241943-242716:1
so has part: feature:241943-242716:1:exon

NP_012200.1
type: Protein
SIO_000068: ncbiprotein

S000001326
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:241943-242716:1:exon

YIL063C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: YRB2
locus tag: YIL063C
so part of: sequence
location: complement(<242761..>243744)
location: region:242761-243744:-1
so has part: feature:242761-243744:-1:exon
subclass of: SO_0000010

854747
type: Gene
SIO_000068: ncbigene

position:242761:-1
position: 242761
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:243744:-1
position: 243744
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:242761-243744:-1:exon

YIL063C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: YRB2
locus tag: YIL063C
product: Yrb2p
transcript id: NM_001179413.1
SIO_010081: YIL063C
subclass of: SO_0000673
so part of: YIL063C
location: complement(<242761..>243744)
location: region:242761-243744:-1
so has part: feature:242761-243744:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:242761-243744:-1:exon

YIL063C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: YRB2
locus tag: YIL063C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:9121474|PMID:9395535|PMID:22932476|PMID:10684247]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:22932476]
experiment: EXISTENCE:mutant phenotype:GO:0000056 ribosomal small subunit export from nucleus [PMID:12082158]
experiment: EXISTENCE:mutant phenotype:GO:0006611 protein export from nucleus [PMID:9636166]
note: hypothetical protein; involved in nuclear processes of the Ran-GTPase cycle; involved in nuclear protein export; contains Ran Binding Domain and FxFG repeats; interacts with Srm1p, GTP-Gsp1p, Rna1p and Crm1p; relocalizes to the cytosol in response to hypoxia; not essential for viability
codon start: 1
product: Yrb2p
translation: MSETNGGNAARENSEVKQTAVENPIDKLDGTPKRPREKDQDEQAEETSDKSEAPNKNDEEKKEEGKKDQEPSHKKIKVDDGKTVESGIVEDDKKEDKFVFGAASKFGTGFGVAKKDTKDGDATTSTESLPASDSKTKKPFAFGSGLSFGSGFNILKNKTENNSESEKKATDVDKDKVHSGSEQLANASEDTKDKPKPLKLQKQEVKSGEESEECIYQVNAKLYQLSNIKEGWKERGVGIIKINKSKDDVEKTRIVMRSRGILKVILNIQLVKGFTVQKGFTGSLQSEKFIRLLAVDDNGDPAQYAIKTGKKETTDELYNIIVKSVPK
SIO_010081: YIL063C
subclass of: SO_0000673
so part of: YIL063C
location: complement(242761..243744)
location: region:242761-243744:-1
so has part: feature:242761-243744:-1:exon

NP_012201.1
type: Protein
SIO_000068: ncbiprotein

S000001325
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:242761-243744:-1:exon

YIL062C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ARC15
locus tag: YIL062C
so part of: sequence
location: complement(<243998..>244462)
location: region:243998-244462:-1
so has part: feature:243998-244462:-1:exon
subclass of: SO_0000010

854748
type: Gene
SIO_000068: ncbigene

position:243998:-1
position: 243998
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:244462:-1
position: 244462
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:243998-244462:-1:exon

YIL062C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ARC15
locus tag: YIL062C
product: Arc15p
transcript id: NM_001179412.1
SIO_010081: YIL062C
subclass of: SO_0000673
so part of: YIL062C
location: complement(<243998..>244462)
location: region:243998-244462:-1
so has part: feature:243998-244462:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:243998-244462:-1:exon

YIL062C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ARC15
locus tag: YIL062C
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:20844764]
experiment: EXISTENCE:direct assay:GO:0005885 Arp2/3 protein complex [PMID:10377407|PMID:9210376]
experiment: EXISTENCE:mutant phenotype:GO:0000001 mitochondrion inheritance [PMID:11248049]
experiment: EXISTENCE:mutant phenotype:GO:0030674 protein-macromolecule adaptor activity [PMID:10377407]
experiment: EXISTENCE:mutant phenotype:GO:0044396 actin cortical patch organization [PMID:10377407]
note: Subunit of the ARP2/3 complex; ARP2/3 is required for the motility and integrity of cortical actin patches; has mRNA binding activity
codon start: 1
product: Arc15p
translation: MEADWRRIDIDAFDPESGRLTAADLVPPYETTVTLQELQPRMNQLRSLATSGDSLGAVQLLTTDPPYSADAPTKEQYFKSVLEALTQVRQADIGNVIKNLSDSQRDVLVKYLYKGMSVPQGQKQGGVLLAWLERITQVSGVTPIVHYISDRRTV
SIO_010081: YIL062C
subclass of: SO_0000673
so part of: YIL062C
location: complement(243998..244462)
location: region:243998-244462:-1
so has part: feature:243998-244462:-1:exon

NP_012202.1
type: Protein
SIO_000068: ncbiprotein

S000001324
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:243998-244462:-1:exon

YIL061C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SNP1
locus tag: YIL061C
so part of: sequence
location: complement(<244657..>245559)
location: region:244657-245559:-1
so has part: feature:244657-245559:-1:exon
subclass of: SO_0000010

854749
type: Gene
SIO_000068: ncbigene

position:244657:-1
position: 244657
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:245559:-1
position: 245559
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:244657-245559:-1:exon

YIL061C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SNP1
locus tag: YIL061C
product: U1 snRNP complex subunit SNP1
transcript id: NM_001179411.1
SIO_010081: YIL061C
subclass of: SO_0000673
so part of: YIL061C
location: complement(<244657..>245559)
location: region:244657-245559:-1
so has part: feature:244657-245559:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:244657-245559:-1:exon

YIL061C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SNP1
locus tag: YIL061C
experiment: EXISTENCE:direct assay:GO:0005685 U1 snRNP [PMID:9630245]
experiment: EXISTENCE:direct assay:GO:0071004 U2-type prespliceosome [PMID:16618970]
experiment: EXISTENCE:physical interaction:GO:0000243 commitment complex [PMID:10072386]
experiment: EXISTENCE:physical interaction:GO:0000398 mRNA splicing, via spliceosome [PMID:10072386]
experiment: EXISTENCE:physical interaction:GO:0003729 mRNA binding [PMID:10072386]
experiment: EXISTENCE:physical interaction:GO:0030619 U1 snRNA binding [PMID:1387202]
note: Component of U1 snRNP required for mRNA splicing via spliceosome; substrate of arginine methyltransferase Hmt1p; may interact with poly(A) polymerase to regulate polyadenylation; homolog of human U1-70K, which has been linked to several types of autoimmune and neurodegenerative diseases
codon start: 1
product: U1 snRNP complex subunit SNP1
translation: MNYNLSKYPDDVSRLFKPRPPLSYKRPTDYPYAKRQTNPNITGVANLLSTSLKHYMEEFPEGSPNNHLQRYEDIKLSKIKNAQLLDRRLQNWNPNVDPHIKDTDPYRTIFIGRLPYDLDEIELQKYFVKFGEIEKIRIVKDKITQKSKGYAFIVFKDPISSKMAFKEIGVHRGIQIKDRICIVDIERGRTVKYFKPRRLGGGLGGRGYSNRDSRLPGRFASASTSNPAERNYAPRLPRRETSSSAYSADRYGSSTLDARYRGNRPLLSAATPTAAVTSVYKSRNSRTRESQPAPKEAPDY
SIO_010081: YIL061C
subclass of: SO_0000673
so part of: YIL061C
location: complement(244657..245559)
location: region:244657-245559:-1
so has part: feature:244657-245559:-1:exon

NP_012203.1
type: Protein
SIO_000068: ncbiprotein

S000001323
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:244657-245559:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS923; Autonomously Replicating Sequence
so part of: sequence
location: 245756..245925
location: region:245756-245925:1
so has part: feature:245756-245925:1:region

S000119034
type: SGD
SIO_000068: sgd

position:245756:1
position: 245756
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:245925:1
position: 245925
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:245756-245925:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty2 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 246220..246552
location: region:246220-246552:1
so has part: feature:246220-246552:1:region

S000007012
type: SGD
SIO_000068: sgd

position:246220:1
position: 246220
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:246552:1
position: 246552
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:246220-246552:1:region

YIL060W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YIL060W
so part of: sequence
location: <246392..>246826
location: region:246392-246826:1
so has part: feature:246392-246826:1:exon
subclass of: SO_0000010

854750
type: Gene
SIO_000068: ncbigene

position:246392:1
position: 246392
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:246826:1
position: 246826
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:246392-246826:1:exon

YIL060W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YIL060W
product: uncharacterized protein
transcript id: NM_001179410.3
SIO_010081: YIL060W
subclass of: SO_0000673
so part of: YIL060W
location: <246392..>246826
location: region:246392-246826:1
so has part: feature:246392-246826:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:246392-246826:1:exon

YIL060W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YIL060W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:24360837]
note: Mitochondrial hypothetical protein; required for respiratory growth; mutant accumulates less glycogen than does wild type; null mutation results in a decrease in plasma membrane electron transport; YIL060W is not an essential gene
codon start: 1
product: uncharacterized protein
translation: MMIIIFIELCRIADSLLWIPKSSRRTSSTFYIPNIIALLKMESQQLSQNSPTLHIHTCGSKIGTLFLRFTKVAIGTSLIVGAGVAMEVSVPLPPQPLYSRSEVPSVELCGIVAICRSPPSVYPTCRPISLSKKIVSGLVRTNSS
SIO_010081: YIL060W
subclass of: SO_0000673
so part of: YIL060W
location: 246392..246826
location: region:246392-246826:1
so has part: feature:246392-246826:1:exon

NP_012204.3
type: Protein
SIO_000068: ncbiprotein

S000001322
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:246392-246826:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS914; Autonomously Replicating Sequence
so part of: sequence
location: 247705..247760
location: region:247705-247760:1
so has part: feature:247705-247760:1:region

S000118397
type: SGD
SIO_000068: sgd

position:247705:1
position: 247705
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:247760:1
position: 247760
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:247705-247760:1:region

YIL057C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RGI2
locus tag: YIL057C
so part of: sequence
location: complement(<247902..>248396)
location: region:247902-248396:-1
so has part: feature:247902-248396:-1:exon
subclass of: SO_0000010

854753
type: Gene
SIO_000068: ncbigene

position:247902:-1
position: 247902
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:248396:-1
position: 248396
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:247902-248396:-1:exon

YIL057C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RGI2
locus tag: YIL057C
product: Rgi2p
transcript id: NM_001179407.3
SIO_010081: YIL057C
subclass of: SO_0000673
so part of: YIL057C
location: complement(<247902..>248396)
location: region:247902-248396:-1
so has part: feature:247902-248396:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:247902-248396:-1:exon

YIL057C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RGI2
locus tag: YIL057C
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0006112 energy reserve metabolic process [PMID:20567505]
note: hypothetical protein; involved in energy metabolism under respiratory conditions; expression induced under carbon limitation and repressed under high glucose; RGI2 has a paralog, RGI1, that arose from the whole genome duplication
codon start: 1
product: Rgi2p
translation: MTKKDKKAKGPKMSTITTKSGESLKVFEDLHDFETYLKGETEDQEFDHVHCQLKYYPPFVLHDAHDDPEKIKETANSHSKKFVRHLHQHVEKHLLKDIKTAINKPELKFHDKKKQESFDRIVWNYGEETELNAKKFKVSVEVVCKHDGAMVDVDYKTEPLQPLI
SIO_010081: YIL057C
subclass of: SO_0000673
so part of: YIL057C
location: complement(247902..248396)
location: region:247902-248396:-1
so has part: feature:247902-248396:-1:exon

NP_012207.3
type: Protein
SIO_000068: ncbiprotein

S000001319
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:247902-248396:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS915; Putative replication origin; identified in multiple array studies, not yet confirmed by plasmid-based assay
so part of: sequence
location: 248396..248850
location: region:248396-248850:1
so has part: feature:248396-248850:1:region

S000130159
type: SGD
SIO_000068: sgd

position:248396:1
position: 248396
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:248850:1
position: 248850
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:248396-248850:1:region

YNCI0006W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SUP17
locus tag: YNCI0006W
so part of: sequence
location: 248850..248931
location: region:248850-248931:1
so has part: feature:248850-248931:1:exon
subclass of: SO_0000663

854754
type: Gene
SIO_000068: ncbigene

position:248931:1
position: 248931
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:248850-248931:1:exon

YNCI0006W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
gene: SUP17
locus tag: YNCI0006W
product: tRNA-Ser
experiment: EXISTENCE:curator inference:GO:0002181 cytoplasmic translation [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Serine tRNA (tRNA-Ser), predicted by tRNAscan-SE analysis; can mutate to suppress ochre nonsense mutations
SIO_010081: YNCI0006W
subclass of: SO_0000673
so part of: YNCI0006W
location: 248850..248931
location: region:248850-248931:1
so has part: feature:248850-248931:1:exon

S000006735
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:248850-248931:1:exon

YIL056W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: VHR1
locus tag: YIL056W
so part of: sequence
location: <249991..>251913
location: region:249991-251913:1
so has part: feature:249991-251913:1:exon
subclass of: SO_0000010

854755
type: Gene
SIO_000068: ncbigene

position:249991:1
position: 249991
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:251913:1
position: 251913
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:249991-251913:1:exon

YIL056W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: VHR1
locus tag: YIL056W
product: Vhr1p
transcript id: NM_001179406.1
SIO_010081: YIL056W
subclass of: SO_0000673
so part of: YIL056W
location: <249991..>251913
location: region:249991-251913:1
so has part: feature:249991-251913:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:249991-251913:1:exon

YIL056W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: VHR1
locus tag: YIL056W
experiment: EXISTENCE:direct assay:GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding [PMID:16533810]
experiment: EXISTENCE:direct assay:GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific [PMID:21278159]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:16533810|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific [PMID:21278159]
experiment: EXISTENCE:mutant phenotype:GO:0006357 regulation of transcription by RNA polymerase II [PMID:16533810|PMID:21278159]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:16533810]
note: Transcriptional activator; required for the vitamin H-responsive element (VHRE) mediated induction of VHT1 (Vitamin H transporter) and BIO5 (biotin biosynthesis intermediate transporter) in response to low biotin concentrations; VHR1 has a paralog, VHR2, that arose from the whole genome duplication
codon start: 1
product: Vhr1p
translation: MNGPPTFTQYRINKFSGNGATHKIRELLNFNDEKKWKQFSSRRLELIDKFQLSQYKASEQDQNIKQIATILRTEFGYPVSCSKEFEKLVTAAVQSVRRNRKRSKKRYALSIANGSGGNVNNSISSNSTSDDEISPSIYQRSNSDFLPSSNYAADFQFSNKFQPLMSHQSHNGTIFPTVGTQNDSSPSVTSTQQKYNDIVTMLVHDLVTNVVPLSEQALKDPYTGPNLSHFATSSLSQQPNITTNIPIDSTVPFFLREKLLLQIQRSRTCQDISQAAGSIDIYANLEILGEMSIRMSIAFVIERFFSNLVSSSMKYITAKTCSPENLALLSQRLFGAATRHNLSHFPAAQVQLRLLYLVIGGIVKDFGFDPTLYPLSEIIHHIVMVQYPLASSCASEPPSSSPNKRVKRSPPVVSSDVMLNNNNTLSNRATLLTTLPMKPQSANKDVNRRVIIRFNDREQAFTFHQLSNGPPTVSEVLENCKNLFNIINKNKNFGIFHNDNLLNDESLAKLFDSFSTSEIHLVIKDISTIPLQDAKIPVPITLPKMSCIGENPSMPSIPLVPQEKDDPKKSSLTAFDNILNRISKSPMNEENSNTTLNTGTSTSNTNNNDHNESVPAPYVTKNKNSFQNGNLPQPVFQPLL
SIO_010081: YIL056W
subclass of: SO_0000673
so part of: YIL056W
location: 249991..251913
location: region:249991-251913:1
so has part: feature:249991-251913:1:exon

NP_012208.1
type: Protein
SIO_000068: ncbiprotein

S000001318
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:249991-251913:1:exon

YIL055C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YIL055C
so part of: sequence
location: complement(<252042..>253925)
location: region:252042-253925:-1
so has part: feature:252042-253925:-1:exon
subclass of: SO_0000010

854756
type: Gene
SIO_000068: ncbigene

position:252042:-1
position: 252042
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:253925:-1
position: 253925
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:252042-253925:-1:exon

YIL055C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YIL055C
product: uncharacterized protein
transcript id: NM_001179405.1
SIO_010081: YIL055C
subclass of: SO_0000673
so part of: YIL055C
location: complement(<252042..>253925)
location: region:252042-253925:-1
so has part: feature:252042-253925:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:252042-253925:-1:exon

YIL055C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YIL055C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:24390141]
codon start: 1
product: uncharacterized protein
translation: MTLEPHYSAKSAASASAFVARSATESSTASTKAAPRKKTYSQSNGIPIRIDNLPPGKTWAQVKYLIGGIIYHTNILQVKMLPPMTSMVPPFITFQSCIVILKNSIDNESLENLLLTLNTYQWDYHDLFVYLLPYTNDSPSLRYPEISDSNNDVRSAPDETKRSISPRYASHVSSVTPQPPSASTPPSQFFSFSPEVSLRKNENITPLPTPVPVPVGVPPLAPPPHGPFSTSMLPMLGAPPGTVPNMQMPYQTTLPSPTAAATAGGPLASPTHYPRRRHFYHQNQSQFQKYMHNSPRNPDTGTGPRLSQQHHLSLRNNKINPSYNEISALYNLNMASNSNNNGNIPTTSTNGDDRALQAKNGGTITPSQTQINHKRLKHIFNEKSFRKQMTNRGMWQLKIINFPPYIPIEFLEKLSESDFNELMNQEKFTVIEIKEKGQLEKFGRLRWTVLKDFIKLKCPKLLRLQERQFLQQQNEASLLNESMDALKISENENTNGSANNSTYTNGGPRTSINNTREFYVGVYEDHEEATLLRFELPEDELEEFNRNLPTTFAQSGNVSDSEGDSKAKYFKVSTIVYNAIVGFHDKELSDLTFESLQDQEYSLGYKIHVMELPPFDEDEFENQRQQF
SIO_010081: YIL055C
subclass of: SO_0000673
so part of: YIL055C
location: complement(252042..253925)
location: region:252042-253925:-1
so has part: feature:252042-253925:-1:exon

NP_012209.1
type: Protein
SIO_000068: ncbiprotein

S000001317
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:252042-253925:-1:exon

YIL054W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YIL054W
so part of: sequence
location: <254543..>254860
location: region:254543-254860:1
so has part: feature:254543-254860:1:exon
subclass of: SO_0000010

854757
type: Gene
SIO_000068: ncbigene

position:254543:1
position: 254543
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:254860:1
position: 254860
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:254543-254860:1:exon

YIL054W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YIL054W
product: uncharacterized protein
transcript id: NM_001270751.1
SIO_010081: YIL054W
subclass of: SO_0000673
so part of: YIL054W
location: <254543..>254860
location: region:254543-254860:1
so has part: feature:254543-254860:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:254543-254860:1:exon

YIL054W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YIL054W
note: hypothetical protein; expressed at both mRNA and protein levels
codon start: 1
product: uncharacterized protein
translation: MAPKAFFVCLPWVLPRHALIVRQAGNPYHFLAYTNPRAPGKLQDSHCPVFFMGIIIITIITVTLAIIIINIIFLTLFDDGMCFYCSLLTFSFVSFNFDHFDHFDL
SIO_010081: YIL054W
subclass of: SO_0000673
so part of: YIL054W
location: 254543..254860
location: region:254543-254860:1
so has part: feature:254543-254860:1:exon

NP_001257680.1
type: Protein
SIO_000068: ncbiprotein

S000001316
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:254543-254860:1:exon

YIL053W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RHR2
gene: GPP1
locus tag: YIL053W
gene synonym: RHR2
so part of: sequence
location: <255115..>255867
location: region:255115-255867:1
so has part: feature:255115-255867:1:exon
subclass of: SO_0000010

854758
type: Gene
SIO_000068: ncbigene

position:255115:1
position: 255115
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:255867:1
position: 255867
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:255115-255867:1:exon

YIL053W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RHR2
gene: GPP1
locus tag: YIL053W
gene synonym: RHR2
product: glycerol-1-phosphatase RHR2
transcript id: NM_001179403.1
SIO_010081: YIL053W
subclass of: SO_0000673
so part of: YIL053W
location: <255115..>255867
location: region:255115-255867:1
so has part: feature:255115-255867:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:255115-255867:1:exon

YIL053W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RHR2
gene: GPP1
locus tag: YIL053W
gene synonym: RHR2
EC number: 3.1.3.21
experiment: EXISTENCE:direct assay:GO:0000121 glycerol-1-phosphatase activity [PMID:8662716]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:27385335|PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0006114 glycerol biosynthetic process [PMID:11058591]
note: Constitutively expressed DL-glycerol-3-phosphate phosphatase; also known as glycerol-1-phosphatase; involved in glycerol biosynthesis, induced in response to both anaerobic and osmotic stress; GPP1 has a paralog, GPP2, that arose from the whole genome duplication
codon start: 1
product: glycerol-1-phosphatase RHR2
translation: MPLTTKPLSLKINAALFDVDGTIIISQPAIAAFWRDFGKDKPYFDAEHVIHISHGWRTYDAIAKFAPDFADEEYVNKLEGEIPEKYGEHSIEVPGAVKLCNALNALPKEKWAVATSGTRDMAKKWFDILKIKRPEYFITANDVKQGKPHPEPYLKGRNGLGFPINEQDPSKSKVVVFEDAPAGIAAGKAAGCKIVGIATTFDLDFLKEKGCDIIVKNHESIRVGEYNAETDEVELIFDDYLYAKDDLLKW
SIO_010081: YIL053W
subclass of: SO_0000673
so part of: YIL053W
location: 255115..255867
location: region:255115-255867:1
so has part: feature:255115-255867:1:exon

NP_012211.2
type: Protein
SIO_000068: ncbiprotein

S000001315
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:255115-255867:1:exon

YIL052C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RPL34B
locus tag: YIL052C
so part of: sequence
location: complement(<256226..>257063)
location: region:256226-257063:-1
so has part: feature:256226-257063:-1:exon
subclass of: SO_0000010

854759
type: Gene
SIO_000068: ncbigene

position:256226:-1
position: 256226
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:257063:-1
position: 257063
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:256226-257063:-1:exon

YIL052C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RPL34B
locus tag: YIL052C
product: ribosomal 60S subunit protein L34B
transcript id: NM_001179402.1
SIO_010081: YIL052C
subclass of: SO_0000673
so part of: YIL052C
location: complement(join(<256226..256554,257027..>257063))
location: region:256226-257063:-1
so has part: feature:257027-257063:-1:exon
so has part: feature:256226-256554:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:257027-257063:-1:exon

position:257027:-1
position: 257027
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:256226-256554:-1:exon

position:256554:-1
position: 256554
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YIL052C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RPL34B
locus tag: YIL052C
experiment: EXISTENCE:curator inference:GO:0002181 cytoplasmic translation [PMID:11983894]
experiment: EXISTENCE:curator inference:GO:0003735 structural constituent of ribosome [PMID:11983894]
experiment: EXISTENCE:direct assay:GO:0022625 cytosolic large ribosomal subunit [PMID:11983894]
note: Ribosomal 60S subunit protein L34B; homologous to mammalian ribosomal protein L34, no bacterial homolog; RPL34B has a paralog, RPL34A, that arose from the whole genome duplication
codon start: 1
product: ribosomal 60S subunit protein L34B
translation: MAQRVTFRRRNPYNTRSNKIKVVKTPGGILRAQHVKKLATRPKCGDCGSALQGISTLRPRQYATVSKTHKTVSRAYGGSRCANCVKERIVRAFLIEEQKIVKKVVKEQTEAAKKSEKKSKK
SIO_010081: YIL052C
subclass of: SO_0000673
so part of: YIL052C
location: complement(join(256226..256554,257027..257063))
location: region:256226-257063:-1
so has part: feature:257027-257063:-1:exon
so has part: feature:256226-256554:-1:exon

NP_012212.1
type: Protein
SIO_000068: ncbiprotein

S000001314
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:257027-257063:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:256226-256554:-1:exon

YIL051C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: IBM1
gene: MMF1
locus tag: YIL051C
gene synonym: IBM1
so part of: sequence
location: complement(<257843..>258280)
location: region:257843-258280:-1
so has part: feature:257843-258280:-1:exon
subclass of: SO_0000010

854760
type: Gene
SIO_000068: ncbigene

position:257843:-1
position: 257843
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:258280:-1
position: 258280
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:257843-258280:-1:exon

YIL051C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: IBM1
gene: MMF1
locus tag: YIL051C
gene synonym: IBM1
product: isoleucine biosynthesis protein MMF1
transcript id: NM_001179401.3
SIO_010081: YIL051C
subclass of: SO_0000673
so part of: YIL051C
location: complement(<257843..>258280)
location: region:257843-258280:-1
so has part: feature:257843-258280:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:257843-258280:-1:exon

YIL051C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: IBM1
gene: MMF1
locus tag: YIL051C
gene synonym: IBM1
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005759 mitochondrial matrix [PMID:11003673]
experiment: EXISTENCE:genetic interaction:GO:0032543 mitochondrial translation [PMID:15164357]
experiment: EXISTENCE:mutant phenotype:GO:0009097 isoleucine biosynthetic process [PMID:11442631]
note: Mitochondrial protein required for transamination of isoleucine; but not of valine or leucine; may regulate specificity of branched-chain transaminases Bat1p and Bat2p; induction of expression in response to stress is mediated by a Hog1p-regulated antisense RNA and gene looping; interacts genetically with mitochondrial ribosomal protein genes; MMF1 has a paralog, HMF1, that arose from the whole genome duplication
codon start: 1
product: isoleucine biosynthesis protein MMF1
translation: MFLRNSVLRTAPVLRRGITTLTPVSTKLAPPAAASYSQAMKANNFVYVSGQIPYTPDNKPVQGSISEKAEQVFQNVKNILAESNSSLDNIVKVNVFLADMKNFAEFNSVYAKHFHTHKPARSCVGVASLPLNVDLEMEVIAVEKN
SIO_010081: YIL051C
subclass of: SO_0000673
so part of: YIL051C
location: complement(257843..258280)
location: region:257843-258280:-1
so has part: feature:257843-258280:-1:exon

NP_012213.3
type: Protein
SIO_000068: ncbiprotein

S000001313
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:257843-258280:-1:exon

YIL050W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PCL7
locus tag: YIL050W
so part of: sequence
location: <258913..>259770
location: region:258913-259770:1
so has part: feature:258913-259770:1:exon
subclass of: SO_0000010

854761
type: Gene
SIO_000068: ncbigene

position:258913:1
position: 258913
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:259770:1
position: 259770
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:258913-259770:1:exon

YIL050W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PCL7
locus tag: YIL050W
product: Pcl7p
transcript id: NM_001179400.3
SIO_010081: YIL050W
subclass of: SO_0000673
so part of: YIL050W
location: <258913..>259770
location: region:258913-259770:1
so has part: feature:258913-259770:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:258913-259770:1:exon

YIL050W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PCL7
locus tag: YIL050W
experiment: EXISTENCE:direct assay:GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity [PMID:12407105]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:16611745]
experiment: EXISTENCE:direct assay:GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity [PMID:12407105]
experiment: EXISTENCE:genetic interaction:GO:0005979 regulation of glycogen biosynthetic process [PMID:11602261]
experiment: EXISTENCE:genetic interaction:GO:0005981 regulation of glycogen catabolic process [PMID:11602261]
experiment: EXISTENCE:mutant phenotype:GO:0031647 regulation of protein stability [PMID:16611745]
experiment: EXISTENCE:physical interaction:GO:0000307 cyclin-dependent protein kinase holoenzyme complex [PMID:16611745]
note: Pho85p cyclin of the Pho80p subfamily; forms a functional kinase complex with Pho85p which phosphorylates Mmr1p and is regulated by Pho81p; involved in glycogen metabolism, expression is cell-cycle regulated; PCL7 has a paralog, PCL6, that arose from the whole genome duplication
codon start: 1
product: Pcl7p
translation: MELSSPSKKTTTSPINIPGGNRDNLIIGPHSHSFKTDPFSSNNSSLLSKISTNPSLESPFSSKSLLDCSPVQAVKKSLESEAKTHSLDEETNEQTDVKILNIADFPTDELILMISALLNRIITANDETTDVSQQVSDETEDELLTPILAFYGKNVPEIAVVQYLERIQKYCPTTNDIFLSLLVYFDRISKNYGHSSERNGCAKQLFVMDSGNIHRLLITGVTICTKFLSDFFYSNSRYAKVGGISLQELNHLELQFLILCDFKLLVSVEEMQKYANLLYKFWNDQ
SIO_010081: YIL050W
subclass of: SO_0000673
so part of: YIL050W
location: 258913..259770
location: region:258913-259770:1
so has part: feature:258913-259770:1:exon

NP_012214.3
type: Protein
SIO_000068: ncbiprotein

S000001312
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:258913-259770:1:exon

YIL049W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: DFG10
locus tag: YIL049W
so part of: sequence
location: <260158..>260919
location: region:260158-260919:1
so has part: feature:260158-260919:1:exon
subclass of: SO_0000010

854762
type: Gene
SIO_000068: ncbigene

position:260158:1
position: 260158
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:260919:1
position: 260919
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:260158-260919:1:exon

YIL049W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: DFG10
locus tag: YIL049W
product: putative polyprenol reductase
transcript id: NM_001179399.1
SIO_010081: YIL049W
subclass of: SO_0000673
so part of: YIL049W
location: <260158..>260919
location: region:260158-260919:1
so has part: feature:260158-260919:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:260158-260919:1:exon

YIL049W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: DFG10
locus tag: YIL049W
EC number: 1.3.1.94
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0006488 dolichol-linked oligosaccharide biosynthetic process [PMID:20637498]
experiment: EXISTENCE:mutant phenotype:GO:0007124 pseudohyphal growth [PMID:9055077]
experiment: EXISTENCE:mutant phenotype:GO:0019408 dolichol biosynthetic process [PMID:20637498]
note: Probable polyprenol reductase; catalyzes conversion of polyprenol to dolichol, the precursor for N-glycosylation; involved in filamentous growth; mutations in human homolog SRD5A3 confer CDG (Congenital Disorders of Glycosylation); human SRD5A3 can complement yeast null mutant
codon start: 1
product: putative polyprenol reductase
translation: MYFDEEQLLKYTIYAYRLSFFVGICSLFIAKSCLPEFLQYGKTYRPKENSKYSSILERIKKFTVPKAYFSHFYYLATFLSLVTLYFYPKFPIVWIIFGHSLRRLYETLYVLHYTSNSRMNWSHYLVGIWFYSVLLLILNISLYKNSIPNTLNMNAFIIFCIASWDQYKNHVILANLVKYSLPTGRLFRLVCCPHYLDEIIIYSTLLPYEQEFYLTLVWVITSLTISALETKNYYRHKFKDNHVAPYAIIPFII
SIO_010081: YIL049W
subclass of: SO_0000673
so part of: YIL049W
location: 260158..260919
location: region:260158-260919:1
so has part: feature:260158-260919:1:exon

NP_012215.1
type: Protein
SIO_000068: ncbiprotein

S000001311
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:260158-260919:1:exon

YIL048W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: NEO1
locus tag: YIL048W
so part of: sequence
location: <261437..>264892
location: region:261437-264892:1
so has part: feature:261437-264892:1:exon
subclass of: SO_0000010

854763
type: Gene
SIO_000068: ncbigene

position:261437:1
position: 261437
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:264892:1
position: 264892
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:261437-264892:1:exon

YIL048W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: NEO1
locus tag: YIL048W
product: putative aminophospholipid-translocating P4-type ATPase NEO1
transcript id: NM_001179398.1
SIO_010081: YIL048W
subclass of: SO_0000673
so part of: YIL048W
location: <261437..>264892
location: region:261437-264892:1
so has part: feature:261437-264892:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:261437-264892:1:exon

YIL048W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: NEO1
locus tag: YIL048W
EC number: 7.6.2.1
experiment: EXISTENCE:direct assay:GO:0000139 Golgi membrane [PMID:12960419]
experiment: EXISTENCE:direct assay:GO:0005768 endosome [PMID:15314152]
experiment: EXISTENCE:direct assay:GO:0005770 late endosome [PMID:30981741]
experiment: EXISTENCE:direct assay:GO:0005794 Golgi apparatus [PMID:15314152]
experiment: EXISTENCE:direct assay:GO:0005802 trans-Golgi network [PMID:30981741]
experiment: EXISTENCE:direct assay:GO:0030137 COPI-coated vesicle [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [PMID:12960419]
experiment: EXISTENCE:mutant phenotype:GO:0006897 endocytosis [PMID:15314152]
experiment: EXISTENCE:mutant phenotype:GO:0007033 vacuole organization [PMID:15314152]
experiment: EXISTENCE:mutant phenotype:GO:0045332 phospholipid translocation [PMID:27235400]
note: Phospholipid translocase (flippase); involved in generating phospholipid asymmetry in plasma membrane; involved in endocytosis, vacuolar biogenesis and Golgi-to-ER vesicle-mediated transport; localizes to endosomes and Golgi apparatus; targeted to vacuole via AP-3 pathway
codon start: 1
product: putative aminophospholipid-translocating P4-type ATPase NEO1
translation: MPNPPSFKSHKQNLFNSNNNQHANSVDSFDLHLDDSFDAALDSLQINNNPEPLSKHNTVGDRESFEMRTVDDLDNFSNHSSDSHRKSSNTDTHPLMYDNRLSQDDNFKFTNIASSPPSSSNNIFSKALSYLKVSNTKNWSKFGSPIELSDQHIEREIHPDTTPVYDRNRYVSNELSNAKYNAVTFVPTLLYEQFKFFYNLYFLVVALSQAVPALRIGYLSSYIVPLAFVLTVTMAKEAIDDIQRRRRDRESNNELYHVITRNRSIPSKDLKVGDLIKVHKGDRIPADLVLLQSSEPSGESFIKTDQLDGETDWKLRVACPLTQNLSENDLINRISITASAPEKSIHKFLGKVTYKDSTSNPLSVDNTLWANTVLASSGFCIACVVYTGRDTRQAMNTTTAKVKTGLLELEINSISKILCACVFALSILLVAFAGFHNDDWYIDILRYLILFSTIIPVSLRVNLDLAKSVYAHQIEHDKTIPETIVRTSTIPEDLGRIEYLLSDKTGTLTQNDMQLKKIHLGTVSYTSETLDIVSDYVQSLVSSKNDSLNNSKVALSTTRKDMSFRVRDMILTLAICHNVTPTFEDDELTYQAASPDEIAIVKFTESVGLSLFKRDRHSISLLHEHSGKTLNYEILQVFPFNSDSKRMGIIVRDEQLDEYWFMQKGADTVMSKIVESNDWLEEETGNMAREGLRTLVIGRKKLNKKIYEQFQKEYNDASLSMLNRDQQMSQVITKYLEHDLELLGLTGVEDKLQKDVKSSIELLRNAGIKIWMLTGDKVETARCVSISAKLISRGQYVHTITKVTRPEGAFNQLEYLKINRNACLLIDGESLGMFLKHYEQEFFDVVVHLPTVIACRCTPQQKADVALVIRKMTGKRVCCIGDGGNDVSMIQCADVGVGIVGKEGKQASLAADFSITQFCHLTELLLWHGRNSYKRSAKLAQFVMHRGLIIAICQAVYSICSLFEPIALYQGWLMVGYATCYTMAPVFSLTLDHDIEESLTKIYPELYKELTEGKSLSYKTFFVWVLLSLFQGSVIQLFSQAFTSLLDTDFTRMVAISFTALVVNELIMVALEIYTWNKTMLVTEIATLLFYIVSVPFLGDYFDLGYMTTVNYYAGLLVILLISIFPVWTAKAIYRRLHPPSYAKVQEFATP
SIO_010081: YIL048W
subclass of: SO_0000673
so part of: YIL048W
location: 261437..264892
location: region:261437-264892:1
so has part: feature:261437-264892:1:exon

NP_012216.1
type: Protein
SIO_000068: ncbiprotein

S000001310
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:261437-264892:1:exon

YIL047C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SYG1
locus tag: YIL047C
so part of: sequence
location: complement(<265115..>267823)
location: region:265115-267823:-1
so has part: feature:265115-267823:-1:exon
subclass of: SO_0000010

854764
type: Gene
SIO_000068: ncbigene

position:265115:-1
position: 265115
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:267823:-1
position: 267823
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:265115-267823:-1:exon

YIL047C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SYG1
locus tag: YIL047C
product: Syg1p
transcript id: NM_001179397.3
SIO_010081: YIL047C
subclass of: SO_0000673
so part of: YIL047C
location: complement(<265115..>267823)
location: region:265115-267823:-1
so has part: feature:265115-267823:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:265115-267823:-1:exon

YIL047C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SYG1
locus tag: YIL047C
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:7592711]
experiment: EXISTENCE:mutant phenotype:GO:0007165 signal transduction [PMID:7592711]
note: Plasma membrane hypothetical protein; targeted to vacuole via AP-3 pathway; truncation and overexpression suppresses lethality of G-alpha protein deficiency
codon start: 1
product: Syg1p
translation: MKFADHLTESAIPEWRDKYIDYKVGKKKLRRYKEKLDAEEEQSSSYRSWMPSVSVYQTAFQQREPGKSRSDGDYRSGPAFKKDYSALQREFVADFIEDWLISFQLSKCNEFYLWLLKECDKKFEVLQSQLHYYSLQKNYERDNLNRSSSNVDMSTSLYAAGLAGRSDSRVNSIDSDSRSVMYGSMPCTKEAKKPRLSLLAYCQKVLKDNRLLPSWPKRGFSLLQDLRQDASSRGRETFAFGASFLETMTTTQARNLLSNAIIEYYLYLQLVKSFRDINVTGFRKMVKKFDKTCHTRELTTFMSYARTHYTLFKHADANVQLVAQKMQQITSSQPTPTSELSSAQRDKEPITWLETQITEWFTTALTNSPKDRKHNTHKLKKLTIQYSISEQMVHRNNRSIVQMLVVGLGIGVSMTLITYTLYLGISSEETSFTHKILFPLWGGWYMVLLIAFLFLVNCFIWHRTGINYRFIMLGEIQSKNGTQFFNNDFATSKIPLKLYFLTFFIVPCAVCSMLSFALEKLTPLGFLYIGIVSFLFLCPSGLIPYWDKVVHTRKWLVVTLIRLMMSGFFPVEFGDFFLGDIICSLTYSIADIAMFFCVYSHTPNNLCGSSHSRAMGVLSCLPSYWRFMQCLRRFADSGDWFPHLLNAAKYTLGIAYNATLCAYRLSDRSEQRRTPFIVCATLNSILTSAWDLVMDWSFAHNTTSYNWLLRDDLYLAGKKNWENGSYSFSRKLVYYFAMIWDILIRFEWIVYAIAPQTIQQSAVTSFILALLEVLRRFVWIIFRVENEHVANVHLFRVTGDAPLPYPIAQVGDDSMDSSDLGSKAFSSLNDIPITPSHDNNPHSFAEPMPAYRGTFRRRSSVFENISRSIPWAHATDFQRPTVNTVDDRSPETDSESEVESIM
SIO_010081: YIL047C
subclass of: SO_0000673
so part of: YIL047C
location: complement(265115..267823)
location: region:265115-267823:-1
so has part: feature:265115-267823:-1:exon

NP_012217.3
type: Protein
SIO_000068: ncbiprotein

S000001309
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:265115-267823:-1:exon

YIL046W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YIL046W-A
so part of: sequence
location: <268309..>268473
location: region:268309-268473:1
so has part: feature:268309-268473:1:exon
subclass of: SO_0000010

1466492
type: Gene
SIO_000068: ncbigene

position:268309:1
position: 268309
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:268473:1
position: 268473
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:268309-268473:1:exon

YIL046W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YIL046W-A
product: uncharacterized protein
transcript id: NM_001184654.1
SIO_010081: YIL046W-A
subclass of: SO_0000673
so part of: YIL046W-A
location: <268309..>268473
location: region:268309-268473:1
so has part: feature:268309-268473:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:268309-268473:1:exon

YIL046W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YIL046W-A
note: hypothetical protein; identified by expression profiling and mass spectrometry
codon start: 1
product: uncharacterized protein
translation: MMCVCIPKKKLMDWRVYYIYSYVVCLYMCGSDCACICVLACVVQCVCFNVEMRL
SIO_010081: YIL046W-A
subclass of: SO_0000673
so part of: YIL046W-A
location: 268309..268473
location: region:268309-268473:1
so has part: feature:268309-268473:1:exon

NP_878097.1
type: Protein
SIO_000068: ncbiprotein

S000028836
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:268309-268473:1:exon

YIL046W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ZRG11
gene: MET30
locus tag: YIL046W
gene synonym: ZRG11
so part of: sequence
location: <268651..>270573
location: region:268651-270573:1
so has part: feature:268651-270573:1:exon
subclass of: SO_0000010

854765
type: Gene
SIO_000068: ncbigene

position:268651:1
position: 268651
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:270573:1
position: 270573
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:268651-270573:1:exon

YIL046W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ZRG11
gene: MET30
locus tag: YIL046W
gene synonym: ZRG11
product: ubiquitin-binding SDF ubiquitin ligase complex subunit MET30
transcript id: NM_001179396.1
SIO_010081: YIL046W
subclass of: SO_0000673
so part of: YIL046W
location: <268651..>270573
location: region:268651-270573:1
so has part: feature:268651-270573:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:268651-270573:1:exon

YIL046W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ZRG11
gene: MET30
locus tag: YIL046W
gene synonym: ZRG11
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:10637232]
experiment: EXISTENCE:direct assay:GO:0019005 SCF ubiquitin ligase complex [PMID:9716410]
experiment: EXISTENCE:direct assay:GO:0043130 ubiquitin binding [PMID:21070969]
experiment: EXISTENCE:direct assay:GO:0043224 nuclear SCF ubiquitin ligase complex [PMID:10637232]
experiment: EXISTENCE:direct assay:GO:0046685 response to arsenic-containing substance [PMID:15689486]
experiment: EXISTENCE:direct assay:GO:0046686 response to cadmium ion [PMID:15689486]
experiment: EXISTENCE:genetic interaction:GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [PMID:9716410]
experiment: EXISTENCE:mutant phenotype:GO:0000082 G1/S transition of mitotic cell cycle [PMID:15870262]
experiment: EXISTENCE:mutant phenotype:GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle [PMID:15870262]
experiment: EXISTENCE:mutant phenotype:GO:0000209 protein polyubiquitination [PMID:9716410]
note: F-box protein containing five copies of the WD40 motif; controls cell cycle function, sulfur metabolism, and methionine biosynthesis as part of the ubiquitin ligase complex; interacts with and regulates Met4p, localizes within the nucleus; dissociation of Met30p from SCF complex in response to cadmium stress is regulated by Cdc48p
codon start: 1
product: ubiquitin-binding SDF ubiquitin ligase complex subunit MET30
translation: MRRERQRMMSFEDKDKDDLDNSNSNNSSEMTDTAMMPPLKRLLITGSSDDLAQGSSGKKKMTMATRSPSSSPDLATNDSGTRVQPLPEYNFTKFCYRHNPDIQFSPTHTACYKQDLKRTQEINANIAKLPLQEQSDIHHIISKYSNSNDKIRKLILDGILSTSCFPQLSYISSLVTHMIKIDFISILPQELSLKILSYLDCQSLCNATRVCRKWQKLADDDRVWYHMCEQHIDRKCPNCGWGLPLLHMKRARIQQNSTGSSSNADIQTQTTRPWKVIYRERFKVESNWRKGHCRIQEFKGHMDGVLTLQFNYRLLFTGSYDSTIGIWDLFTGKLIRRLSGHSDGVKTLYFDDRKLITGSLDKTIRVWNYITGECISTYRGHSDSVLSVDSYQKVIVSGSADKTVKVWHVESRTCYTLRGHTEWVNCVKLHPKSFSCFSCSDDTTIRMWDIRTNSCLKVFRGHVGQVQKIIPLTIKDVENLATDNTSDGSSPQDDPTMTDGADESDTPSNEQETVLDENIPYPTHLLSCGLDNTIKLWDVKTGKCIRTQFGHVEGVWDIAADNFRIISGSHDGSIKVWDLQSGKCMHTFNGRRLQRETQHTQTQSLGDKVAPIACVCIGDSECFSGDEFGCVKMYKFDLND
SIO_010081: YIL046W
subclass of: SO_0000673
so part of: YIL046W
location: 268651..270573
location: region:268651-270573:1
so has part: feature:268651-270573:1:exon

NP_012218.1
type: Protein
SIO_000068: ncbiprotein

S000001308
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:268651-270573:1:exon

YIL045W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PIG2
locus tag: YIL045W
so part of: sequence
location: <271161..>272777
location: region:271161-272777:1
so has part: feature:271161-272777:1:exon
subclass of: SO_0000010

854766
type: Gene
SIO_000068: ncbigene

position:271161:1
position: 271161
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:272777:1
position: 272777
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:271161-272777:1:exon

YIL045W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PIG2
locus tag: YIL045W
product: putative protein phosphatase regulator PIG2
transcript id: NM_001179395.3
SIO_010081: YIL045W
subclass of: SO_0000673
so part of: YIL045W
location: <271161..>272777
location: region:271161-272777:1
so has part: feature:271161-272777:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:271161-272777:1:exon

YIL045W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PIG2
locus tag: YIL045W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:physical interaction:GO:0005979 regulation of glycogen biosynthetic process [PMID:9046081]
note: Putative type-1 protein phosphatase targeting subunit; tethers Glc7p type-1 protein phosphatase to Gsy2p glycogen synthase; PIG2 has a paralog, GIP2, that arose from the whole genome duplication
codon start: 1
product: putative protein phosphatase regulator PIG2
translation: MATTTQPQNILMDEPLNLPNNSAHNNNYGNINANIRTFAGMSMHMHPARLNSLEFLHKPRRLSNVKLHRLPQDELQRNTDMNKGMYFNGKQVHAHHPFINSGANFNAHHQDVSKLGEEEDEISPLSHDNFQYESEENGNPSPPIYKKSGELVKSSLKRRSKSLPITPKSIFNKTGSKSKHVNLDHVDTRLLQRSKSVHFDRVLPIKLFNENEKPIDVGKQMVQQDVLNFKHKPLTRLSALNGGSDSVPIEDLLSENNQNEYGDTWLQNPKGVFLFGTNSNNRRNKKKKFKLSDDDSDIENDNDSDDAINRLVRQQDKDQAHLAHGLKNLLINDDDDYLETRTNSAKSGANLFIGNSKRIVGLYNKNFPILSDRNRKSLKLNIFLNLSRGRPVFLQEITLLTGFHNMVIIGKVFVKNIYFDKKIIVRYTWDAWRTFHESECVYFSNANGILPGSNMDIFKFSIDDIHNPNDKDSNISQLEFCIQYLTWGVDRSRKEYWDNNDSANYKIDVVTNETRTGPTTDVNDNYEMKHSLFRNPFH
SIO_010081: YIL045W
subclass of: SO_0000673
so part of: YIL045W
location: 271161..272777
location: region:271161-272777:1
so has part: feature:271161-272777:1:exon

NP_012219.3
type: Protein
SIO_000068: ncbiprotein

S000001307
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:271161-272777:1:exon

YIL044C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SAT2
gene: AGE2
locus tag: YIL044C
gene synonym: SAT2
so part of: sequence
location: complement(<272950..>273846)
location: region:272950-273846:-1
so has part: feature:272950-273846:-1:exon
subclass of: SO_0000010

854767
type: Gene
SIO_000068: ncbigene

position:272950:-1
position: 272950
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:273846:-1
position: 273846
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:272950-273846:-1:exon

YIL044C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SAT2
gene: AGE2
locus tag: YIL044C
gene synonym: SAT2
product: GTPase-activating protein AGE2
transcript id: NM_001179394.3
SIO_010081: YIL044C
subclass of: SO_0000673
so part of: YIL044C
location: complement(<272950..>273846)
location: region:272950-273846:-1
so has part: feature:272950-273846:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:272950-273846:-1:exon

YIL044C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SAT2
gene: AGE2
locus tag: YIL044C
gene synonym: SAT2
experiment: EXISTENCE:direct assay:GO:0005096 GTPase activator activity [PMID:12627398]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0030136 clathrin-coated vesicle [PMID:14562095]
experiment: EXISTENCE:genetic interaction:GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport [PMID:9677411]
experiment: EXISTENCE:genetic interaction:GO:0006891 intra-Golgi vesicle-mediated transport [PMID:9677411]
note: ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector; involved in Trans-Golgi-Network (TGN) transport; contains C2C2H2 cysteine/histidine motif
codon start: 1
product: GTPase-activating protein AGE2
translation: MSTSVPVKKALSALLRDPGNSHCADCKAQLHPRWASWSLGVFICIKCAGIHRSLGTHISKVKSVDLDTWKEEHLVKLIQFKNNLRANSYYEATLADELKQRKITDTSSLQNFIKNKYEYKKWIGDLSSIEGLNDSTEPVLHKPSANHSLPASNARLDQSSNSLQKTQTQPPSHLLSTSRSNTSLLNLQVSSLSKTTSNTSVTSSATSIGAANTKTGNRVGEFGQRNDLKKSILSLYSKPSAQTQSQNSFFTSTTPQPCNTPSPFVNTGITATNNNSMNSNSSSNISLDDNELFKNVWS
SIO_010081: YIL044C
subclass of: SO_0000673
so part of: YIL044C
location: complement(272950..273846)
location: region:272950-273846:-1
so has part: feature:272950-273846:-1:exon

NP_012220.3
type: Protein
SIO_000068: ncbiprotein

S000001306
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:272950-273846:-1:exon

YIL043C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CBR5
gene: CBR1
locus tag: YIL043C
gene synonym: CBR5
so part of: sequence
location: complement(<274072..>274926)
location: region:274072-274926:-1
so has part: feature:274072-274926:-1:exon
subclass of: SO_0000010

854768
type: Gene
SIO_000068: ncbigene

position:274072:-1
position: 274072
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:274926:-1
position: 274926
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:274072-274926:-1:exon

YIL043C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CBR5
gene: CBR1
locus tag: YIL043C
gene synonym: CBR5
product: cytochrome-b5 reductase
transcript id: NM_001179393.1
SIO_010081: YIL043C
subclass of: SO_0000673
so part of: YIL043C
location: complement(<274072..>274926)
location: region:274072-274926:-1
so has part: feature:274072-274926:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:274072-274926:-1:exon

YIL043C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CBR5
gene: CBR1
locus tag: YIL043C
gene synonym: CBR5
EC number: 1.6.2.2
experiment: EXISTENCE:direct assay:GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H [PMID:14930|PMID:27694803]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005741 mitochondrial outer membrane [PMID:16407407]
experiment: EXISTENCE:mutant phenotype:GO:0002098 tRNA wobble uridine modification [PMID:27694803]
note: Cytochrome b reductase and NADH-dependent reductase for Dph3p; required for diphthamide synthesis and tRNA wobble uridine modification; also detected in mitochondria; mutation in conserved NADH binding domain of the human ortholog results in type I methemoglobinemia
codon start: 1
product: cytochrome-b5 reductase
translation: MAIDAQKLVVVIVIVVVPLLFKFIIGPKTKPVLDPKRNDFQSFPLVEKTILTHNTSMYKFGLPHADDVLGLPIGQHIVIKANINGKDITRSYTPTSLDGDTKGNFELLVKSYPTGNVSKMIGELKIGDSIQIKGPRGNYHYERNCRSHLGMIAGGTGIAPMYQIMKAIAMDPHDTTKVSLVFGNVHEEDILLKKELEALVAMKPSQFKIVYYLDSPDREDWTGGVGYITKDVIKEHLPAATMDNVQILICGPPAMVASVRRSTVDLGFRRSKPLSKMEDQVFVF
SIO_010081: YIL043C
subclass of: SO_0000673
so part of: YIL043C
location: complement(274072..274926)
location: region:274072-274926:-1
so has part: feature:274072-274926:-1:exon

NP_012221.2
type: Protein
SIO_000068: ncbiprotein

S000001305
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:274072-274926:-1:exon

YIL042C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PKP1
locus tag: YIL042C
so part of: sequence
location: complement(<275108..>276292)
location: region:275108-276292:-1
so has part: feature:275108-276292:-1:exon
subclass of: SO_0000010

854769
type: Gene
SIO_000068: ncbigene

position:275108:-1
position: 275108
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:276292:-1
position: 276292
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:275108-276292:-1:exon

YIL042C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PKP1
locus tag: YIL042C
product: protein kinase PKP1
transcript id: NM_001179392.1
SIO_010081: YIL042C
subclass of: SO_0000673
so part of: YIL042C
location: complement(<275108..>276292)
location: region:275108-276292:-1
so has part: feature:275108-276292:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:275108-276292:-1:exon

YIL042C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PKP1
locus tag: YIL042C
EC number: 2.7.11.2
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:17918780]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16643908|PMID:16823961|PMID:24769239|PMID:17918780]
experiment: EXISTENCE:genetic interaction:GO:0015976 carbon utilization [PMID:17918780]
experiment: EXISTENCE:mutant phenotype:GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity [PMID:18180296|PMID:16643908]
experiment: EXISTENCE:mutant phenotype:GO:0065003 protein-containing complex assembly [PMID:16643908]
experiment: EXISTENCE:mutant phenotype:GO:1901524 regulation of mitophagy [PMID:31548421]
note: Mitochondrial protein kinase; involved in negative regulation of pyruvate dehydrogenase complex activity by phosphorylating the ser-133 residue of the Pda1p subunit; acts in concert with kinase Pkp2p and phosphatases Ptc5p and Ptc6p
codon start: 1
product: protein kinase PKP1
translation: MWKIMRSWKCGGMRWAHRQRPSHELLSQLSFDQHYKIRSNIELLIQDYASKPIAPLNYEYFLQYRPPLTKKEEYMLTIKTINLLLSLTCKRLNAIQRLPYNAVINPHIERTNSLYLKSLQTLLSIAYPYELHNPPKIQAKFTELLDDHEDAIVVLAKGLQEIQSCYPKFQISQFLNFHLKERITMKLLVTHYLSLMAQNKGDTNKRMIGILHRDLPIAQLIKHVSDYVNDICFVKFNTQRTPVLIHPPSQDITFTCIPPILEYIMTEVFKNAFEAQIALGKEHMPIEINLLKPDDDELYLRIRDHGGGITPEVEALMFNYSYSTHTQQSADSESTDLPGEQINNVSGMGFGLPMCKTYLELFGGKIDVQSLLGWGTDVYIKLKGPSKTALLSKK
SIO_010081: YIL042C
subclass of: SO_0000673
so part of: YIL042C
location: complement(275108..276292)
location: region:275108-276292:-1
so has part: feature:275108-276292:-1:exon

NP_012222.1
type: Protein
SIO_000068: ncbiprotein

S000001304
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:275108-276292:-1:exon

YIL041W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GVP36
locus tag: YIL041W
so part of: sequence
location: <276525..>277505
location: region:276525-277505:1
so has part: feature:276525-277505:1:exon
subclass of: SO_0000010

854770
type: Gene
SIO_000068: ncbigene

position:276525:1
position: 276525
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:277505:1
position: 277505
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:276525-277505:1:exon

YIL041W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GVP36
locus tag: YIL041W
product: Gvp36p
transcript id: NM_001179391.3
SIO_010081: YIL041W
subclass of: SO_0000673
so part of: YIL041W
location: <276525..>277505
location: region:276525-277505:1
so has part: feature:276525-277505:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:276525-277505:1:exon

YIL041W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GVP36
locus tag: YIL041W
experiment: EXISTENCE:direct assay:GO:0000139 Golgi membrane [PMID:16107716]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0006897 endocytosis [PMID:18156177]
experiment: EXISTENCE:mutant phenotype:GO:0007033 vacuole organization [PMID:18156177]
experiment: EXISTENCE:mutant phenotype:GO:0030950 establishment or maintenance of actin cytoskeleton polarity [PMID:18156177]
note: BAR domain protein that localizes to early and late Golgi vesicles; required for adaptation to varying nutrient concentrations, fluid-phase endocytosis, polarization of the actin cytoskeleton, and vacuole biogenesis
codon start: 1
product: Gvp36p
translation: MSFNAFASSLSKKLQEISTSVSEKTQELPSLAQSTQRMVQERLGQVTDISQLPREYTELEDKVDTIKLIYNHFLGVTAIYENGSYDYPKYINESVNEFSRSVASKLTELTHATSASEAQNILVAPGPIKEPKTLNYALSKVALNSSECLNKMFPTEEQPLASALLQFSDVQAKIAQARIQQDTLIQTKFNKNLRERLSFEIGKADKCRKDVHSMRLRYDVARTNLANNKKPEKEASLRVQMETLEDQFAQVTEDATVCLQEVISHANFSEDLKELAKAQAEYFETSAGLMKEFLSNSFAEEPEAKPEVAEEEKPQTAISMNDEDDA
SIO_010081: YIL041W
subclass of: SO_0000673
so part of: YIL041W
location: 276525..277505
location: region:276525-277505:1
so has part: feature:276525-277505:1:exon

NP_012223.3
type: Protein
SIO_000068: ncbiprotein

S000001303
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:276525-277505:1:exon

YIL040W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: APQ12
locus tag: YIL040W
so part of: sequence
location: <277723..>278139
location: region:277723-278139:1
so has part: feature:277723-278139:1:exon
subclass of: SO_0000010

854771
type: Gene
SIO_000068: ncbigene

position:277723:1
position: 277723
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:278139:1
position: 278139
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:277723-278139:1:exon

YIL040W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: APQ12
locus tag: YIL040W
product: Apq12p
transcript id: NM_001179390.1
SIO_010081: YIL040W
subclass of: SO_0000673
so part of: YIL040W
location: <277723..>278139
location: region:277723-278139:1
so has part: feature:277723-278139:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:277723-278139:1:exon

YIL040W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: APQ12
locus tag: YIL040W
experiment: EXISTENCE:direct assay:GO:0005635 nuclear envelope [PMID:15273328|PMID:26432634]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:15273328|PMID:26432634|PMID:14562095|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0016020 membrane [PMID:17724120]
experiment: EXISTENCE:genetic interaction:GO:0055088 lipid homeostasis [PMID:20016074|PMID:26432634]
experiment: EXISTENCE:mutant phenotype:GO:0006998 nuclear envelope organization [PMID:17724120|PMID:20016074]
experiment: EXISTENCE:mutant phenotype:GO:0055088 lipid homeostasis [PMID:20016074|PMID:26432634]
note: Nuclear envelope/ER integral membrane protein; interacts and functions with Brr6p and Brl1p in lipid homeostasis; mutants are defective in nuclear pore complex biogenesis, nuclear envelope morphology, mRNA export from the nucleus and are sensitive to sterol biosynthesis inhibitors and membrane fluidizing agents; exhibits synthetic lethal genetic interactions with genes involved in lipid metabolism
codon start: 1
product: Apq12p
translation: MDATQPQYELSVVTQCLKSAIDVIQWLIPTITKFSQSHPLVFQLLFIFFTFYVFYKLLMNFITLVKRFLYLTLVVTCIGIYMRGSQQFLTVDLLNFYNFVMSNRYYAFKIYTLFINALEREINTVYHLAQMKMEQLLK
SIO_010081: YIL040W
subclass of: SO_0000673
so part of: YIL040W
location: 277723..278139
location: region:277723-278139:1
so has part: feature:277723-278139:1:exon

NP_012224.1
type: Protein
SIO_000068: ncbiprotein

S000001302
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:277723-278139:1:exon

YIL039W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TED1
locus tag: YIL039W
so part of: sequence
location: <278426..>279847
location: region:278426-279847:1
so has part: feature:278426-279847:1:exon
subclass of: SO_0000010

854772
type: Gene
SIO_000068: ncbigene

position:278426:1
position: 278426
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:279847:1
position: 279847
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:278426-279847:1:exon

YIL039W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TED1
locus tag: YIL039W
product: Ted1p
transcript id: NM_001179389.1
SIO_010081: YIL039W
subclass of: SO_0000673
so part of: YIL039W
location: <278426..>279847
location: region:278426-279847:1
so has part: feature:278426-279847:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:278426-279847:1:exon

YIL039W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TED1
locus tag: YIL039W
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:14562095|PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport [PMID:17989219]
experiment: EXISTENCE:mutant phenotype:GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport [PMID:17989219]
note: GPI-glycan remodelase; conserved phosphoesterase domain-containing protein; acts together with Emp24p/Erv25p in cargo exit from the ER; functional ortholog of mammalian GPI-glycan remodelase PGAP5; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO)
codon start: 1
product: Ted1p
translation: MLRCAVKKFAYFATFLTIVANIYIYTYPSFHPEQCSWNCSNKNAPLQKDLTFVDKVKNYFSDVREQWHGSHASAGNDEDIHILAFGDPQIKGIWPKTPYVSRLDTYGNDYYLGHIYDMMQQRLKPQVVTVMGDLFSSQWIGDSEFHNRTKRYISRIFKRDPTSIENIKQQNLDEKGQYKANWPEWGDRFNEILDNVKENEADNQELSFGFGYENIHSWNPDLEDFLIINITGNHDVGYSGDATYQHMTRFHDLFGKDNYWIEYETNTTHPWRIVVLNDLLLEGPALQPEFVEATWIFLNQLNERKFNGSTVLLTHVPFYKREGLCVDGPDTRYYPDAHAPESYKSGLLRSQNHLSESVSNQVLNMIFENGKPGIILTGHDHEGCETVYNKKSTSTWEATKNIESDVFVKEITVKSMMGEFNGNTGLVTGHFNTDSMTWEWTFSLCPFAIQHVWWFAKVSLLVTIFTWSSLLFV
SIO_010081: YIL039W
subclass of: SO_0000673
so part of: YIL039W
location: 278426..279847
location: region:278426-279847:1
so has part: feature:278426-279847:1:exon

NP_012225.1
type: Protein
SIO_000068: ncbiprotein

S000001301
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:278426-279847:1:exon

YIL038C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: NOT3
locus tag: YIL038C
so part of: sequence
location: complement(<280142..>282652)
location: region:280142-282652:-1
so has part: feature:280142-282652:-1:exon
subclass of: SO_0000010

854773
type: Gene
SIO_000068: ncbigene

position:280142:-1
position: 280142
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:282652:-1
position: 282652
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:280142-282652:-1:exon

YIL038C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: NOT3
locus tag: YIL038C
product: CCR4-NOT core subunit NOT3
transcript id: NM_001179388.3
SIO_010081: YIL038C
subclass of: SO_0000673
so part of: YIL038C
location: complement(<280142..>282652)
location: region:280142-282652:-1
so has part: feature:280142-282652:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:280142-282652:-1:exon

YIL038C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: NOT3
locus tag: YIL038C
experiment: EXISTENCE:direct assay:GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening [PMID:11889048]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11889048]
experiment: EXISTENCE:direct assay:GO:0032968 positive regulation of transcription elongation by RNA polymerase II [PMID:21406554]
experiment: EXISTENCE:mutant phenotype:GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA [PMID:26952104]
experiment: EXISTENCE:mutant phenotype:GO:0016567 protein ubiquitination [PMID:16926149]
experiment: EXISTENCE:physical interaction:GO:0005515 protein binding [PMID:26952104]
experiment: EXISTENCE:physical interaction:GO:0030015 CCR4-NOT core complex [PMID:10490603]
note: Component of the CCR4-NOT core complex, involved in mRNA decapping; involved in transcription initiation and elongation and in mRNA degradation; conserved lysine in human homolog of Not3p and Not5p is mutated in cancers
codon start: 1
product: CCR4-NOT core subunit NOT3
translation: MAHRKLQQEVDRVFKKINEGLEIFNSYYERHESCTNNPSQKDKLESDLKREVKKLQRLREQIKSWQSSPDIKDKDSLLDYRRSVEIAMEKYKAVEKASKEKAYSNISLKKSETLDPQERERRDISEYLSQMIDELERQYDSLQVEIDKLLLLNKKKKTSSTTNDEKKEQYKRFQARYRWHQQQMELALRLLANEELDPQDVKNVQDDINYFVESNQDPDFVEDETIYDGLNLQSNEAIAHEVAQYFASQNAEDNNTSDANESLQDISKLSKKEQRKLEREAKKAAKLAAKNATGAAIPVAGPSSTPSPVIPVADASKETERSPSSSPIHNATKPEEAVKTSIKSPRSSADNLLPSLQKSPSSATPETPTNVHTHIHQTPNGITGATTLKPATLPAKPAGELKWAVAASQAVEKDRKVTSASSTISNTSTKTPTTAAATTTSSNANSRIGSALNTPKLSTSSLSLQPDNTGASSSAATAAAVLAAGAAAVHQNNQAFYRNMSSSHHPLVSLATNPKSEHEVATTVNQNGPENTTKKVMEQKEEESPEERNKLQVPTFGVFDDDFESDRDSETEPEEEEQPSTPKYLSLEQREAKTNEIKKEFVSDFETLLLPSGVQEFIMSSELYNSQIESKITYKRSRDMCEISRLVEVPQGVNPPSPLDAFRSTQQWDVMRCSLRDIIIGSERLKEDSSSIYAKILENFRTLEMFSLFYNYYFAITPLEREIAYKILNERDWKVSKDGTMWFLRQGEVKFFNEICEVGDYKIFKLDDWTVIDKINFRLDYSFLQPPVDTASEVRDVSVDNNNVNDQSNVTLEQQKQEISHGKQLLKQLKQGKISV
SIO_010081: YIL038C
subclass of: SO_0000673
so part of: YIL038C
location: complement(280142..282652)
location: region:280142-282652:-1
so has part: feature:280142-282652:-1:exon

NP_012226.3
type: Protein
SIO_000068: ncbiprotein

S000001300
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:280142-282652:-1:exon

YIL037C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PRM2
locus tag: YIL037C
so part of: sequence
location: complement(<283029..>284999)
location: region:283029-284999:-1
so has part: feature:283029-284999:-1:exon
subclass of: SO_0000010

854774
type: Gene
SIO_000068: ncbigene

position:283029:-1
position: 283029
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:284999:-1
position: 284999
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:283029-284999:-1:exon

YIL037C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PRM2
locus tag: YIL037C
product: pheromone-regulated protein PRM2
transcript id: NM_001179387.3
SIO_010081: YIL037C
subclass of: SO_0000673
so part of: YIL037C
location: complement(<283029..>284999)
location: region:283029-284999:-1
so has part: feature:283029-284999:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:283029-284999:-1:exon

YIL037C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PRM2
locus tag: YIL037C
experiment: EXISTENCE:mutant phenotype:GO:0000742 karyogamy involved in conjugation with cellular fusion [PMID:17101777]
note: Pheromone-regulated protein; predicted to have 4 transmembrane segments and a coiled coil domain; regulated by Ste12p; required for efficient nuclear fusion
codon start: 1
product: pheromone-regulated protein PRM2
translation: MNNVHIIKPLSLPQRFFSCIFHPLLLIFFTSVILTIWGSFSVIDITMAKMSHAQVKRNDTVSTFASISTATATATTTATTTATMTAVTTQHAIYSANSYSLNKTFIDNTIDQYFESKLRSIESTVGTDMQEKFKSYTDDILDNKQKLINDQISLETELIKEVLEVNNTIFNELLTKSQLINDTWNEISEDAMTIDKDSISQMASNLLLNYSMFDSIFGNYSRKLKSLQNFNGTITDFSTQLDTSSTLSLNFLRNSTDWLQLKRNFTANLQNEISILSGGSTEVTSSTSIIKRSLKTNSEENSVLSAVKNHVFRKCKRMTIIFTVMYFAFVILLMAIERILFQLENQQVNLVMSQINGLTGQTNFTKYNKVLKSLITTLNLSTLYPIPYQLTKLINQKIFKREPEKIDDKKVKKSKLFYCNWWIISNGAHLWLFGFLMLLIHWQIVTRLTNFEVPSLPTFHKRAGPSLYKREVWTDGNITTTIEGFINDSVSLLCENFQMEVNEKFITANLSLQTDPNLKVQSTDILNLWVNDTNTQFEKYLNESSQNWQGIDLQVEPLLGSDSINEFLGQYFLPTYEVTNTNSSFALDIQKYGIINRGINITNASVAALSSLSKRQIKDKEQKQTYFLHTVYKWGLLAVCLTILFHHMLIFIILKL
SIO_010081: YIL037C
subclass of: SO_0000673
so part of: YIL037C
location: complement(283029..284999)
location: region:283029-284999:-1
so has part: feature:283029-284999:-1:exon

NP_012227.3
type: Protein
SIO_000068: ncbiprotein

S000001299
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:283029-284999:-1:exon

YIL036W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ACA2
alternative label: SHF1
gene: CST6
locus tag: YIL036W
gene synonym: ACA2; SHF1
so part of: sequence
location: <285666..>287429
location: region:285666-287429:1
so has part: feature:285666-287429:1:exon
subclass of: SO_0000010

854775
type: Gene
SIO_000068: ncbigene

position:285666:1
position: 285666
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:287429:1
position: 287429
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:285666-287429:1:exon

YIL036W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ACA2
alternative label: SHF1
gene: CST6
locus tag: YIL036W
gene synonym: ACA2; SHF1
product: Cst6p
transcript id: NM_001179386.1
SIO_010081: YIL036W
subclass of: SO_0000673
so part of: YIL036W
location: <285666..>287429
location: region:285666-287429:1
so has part: feature:285666-287429:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:285666-287429:1:exon

YIL036W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ACA2
alternative label: SHF1
gene: CST6
locus tag: YIL036W
gene synonym: ACA2; SHF1
experiment: EXISTENCE:direct assay:GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific [PMID:10825197]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0006357 regulation of transcription by RNA polymerase II [PMID:27143390]
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:10825197|PMID:27143390]
experiment: EXISTENCE:direct assay:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:10825197]
experiment: EXISTENCE:mutant phenotype:GO:0061429 positive regulation of transcription from RNA polymerase II promoter by oleic acid [PMID:20395639]
experiment: EXISTENCE:mutant phenotype:GO:0071244 cellular response to carbon dioxide [PMID:22253597]
experiment: EXISTENCE:mutant phenotype:GO:0071400 cellular response to oleic acid [PMID:20395639]
note: Basic leucine zipper (bZIP) transcription factor from ATF/CREB family involved in stress-responsive regulatory network; mediates transcriptional activation of NCE103 in response to low CO2 levels; proposed to be a regulator of oleate responsive genes; involved in utilization of non-optimal carbon sources and chromosome stability; relocalizes to the cytosol in response to hypoxia; CST6 has a paralog, ACA1, that arose from the whole genome duplication
codon start: 1
product: Cst6p
translation: MFTGQEYHSVDSNSNKQKDNNKRGIDDTSKILNNKIPHSVSDTSAAATTTSTMNNSALSRSLDPTDINYSTNMAGVVDQIHDYTTSNRNSLTPQYSIAAGNVNSHDRVVKPSANSNYQQAAYLRQQQQQDQRQQSPSMKTEEESQLYGDILMNSGVVQDMHQNLATHTNLSQLSSTRKSAPNDSTTAPTNASNIANTASVNKQMYFMNMNMNNNPHALNDPSILETLSPFFQPFGVDVAHLPMTNPPIFQSSLPGCDEPIRRRRISISNGQISQLGEDIETLENLHNTQPPPMPNFHNYNGLSQTRNVSNKPVFNQAVPVSSIPQYNAKKVINPTKDSALGDQSVIYSKSQQRNFVNAPSKNTPAESISDLEGMTTFAPTTGGENRGKSALRESHSNPSFTPKSQGSHLNLAANTQGNPIPGTTAWKRARLLERNRIAASKCRQRKKVAQLQLQKEFNEIKDENRILLKKLNYYEKLISKFKKFSKIHLREHEKLNKDSDNNVNGTNSSNKNESMTVDSLKIIEELLMIDSDVTEVDKDTGKIIAIKHEPYSQRFGSDTDDDDIDLKPVEGGKDPDNQSLPNSEKIK
SIO_010081: YIL036W
subclass of: SO_0000673
so part of: YIL036W
location: 285666..287429
location: region:285666-287429:1
so has part: feature:285666-287429:1:exon

NP_012228.1
type: Protein
SIO_000068: ncbiprotein

S000001298
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:285666-287429:1:exon

YIL035C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CKA1
locus tag: YIL035C
so part of: sequence
location: complement(<287790..>288908)
location: region:287790-288908:-1
so has part: feature:287790-288908:-1:exon
subclass of: SO_0000010

854776
type: Gene
SIO_000068: ncbigene

position:287790:-1
position: 287790
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:288908:-1
position: 288908
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:287790-288908:-1:exon

YIL035C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CKA1
locus tag: YIL035C
product: casein kinase 2 catalytic subunit CKA1
transcript id: NM_001179385.1
SIO_010081: YIL035C
subclass of: SO_0000673
so part of: YIL035C
location: complement(<287790..>288908)
location: region:287790-288908:-1
so has part: feature:287790-288908:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:287790-288908:-1:exon

YIL035C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CKA1
locus tag: YIL035C
EC number: 2.7.11.1
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:16319894]
experiment: EXISTENCE:direct assay:GO:0004674 protein serine/threonine kinase activity [PMID:8226802]
experiment: EXISTENCE:direct assay:GO:0005956 protein kinase CK2 complex [PMID:8135547]
experiment: EXISTENCE:direct assay:GO:0006356 regulation of transcription by RNA polymerase I [PMID:11551505]
experiment: EXISTENCE:direct assay:GO:0006359 regulation of transcription by RNA polymerase III [PMID:11551505]
experiment: EXISTENCE:direct assay:GO:0006974 cellular response to DNA damage stimulus [PMID:11551505]
experiment: EXISTENCE:direct assay:GO:0034456 UTP-C complex [PMID:17515605]
experiment: EXISTENCE:genetic interaction:GO:0007535 donor selection [PMID:22496671]
note: Alpha catalytic subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; regulates Fkh1p-mediated donor preference during mating-type switching
codon start: 1
product: casein kinase 2 catalytic subunit CKA1
translation: MKCRVWSEARVYTNINKQRTEEYWDYENTVIDWSTNTKDYEIENKVGRGKYSEVFQGVKLDSKVKIVIKMLKPVKKKKIKREIKILTDLSNEKVPPTTLPFQKDQYYTNQKEDVLKFIRPYIFDQPHNGHANIIHLFDIIKDPISKTPALVFEYVDNVDFRILYPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLGTSDFEKYLLKYEITLPREFYDMDQYIRKPWHRFINDGNKHLSGNDEIIDLIDNLLRYDHQERLTAKEAMGHPWFAPIREQIEK
SIO_010081: YIL035C
subclass of: SO_0000673
so part of: YIL035C
location: complement(287790..288908)
location: region:287790-288908:-1
so has part: feature:287790-288908:-1:exon

NP_012229.1
type: Protein
SIO_000068: ncbiprotein

S000001297
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:287790-288908:-1:exon

YIL034C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CAP2
locus tag: YIL034C
so part of: sequence
location: complement(<289226..>290089)
location: region:289226-290089:-1
so has part: feature:289226-290089:-1:exon
subclass of: SO_0000010

854777
type: Gene
SIO_000068: ncbigene

position:289226:-1
position: 289226
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:290089:-1
position: 290089
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:289226-290089:-1:exon

YIL034C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CAP2
locus tag: YIL034C
product: F-actin-capping protein subunit beta
transcript id: NM_001179384.3
SIO_010081: YIL034C
subclass of: SO_0000673
so part of: YIL034C
location: complement(<289226..>290089)
location: region:289226-290089:-1
so has part: feature:289226-290089:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:289226-290089:-1:exon

YIL034C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CAP2
locus tag: YIL034C
experiment: EXISTENCE:direct assay:GO:0000131 incipient cellular bud site [PMID:1315784]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005934 cellular bud tip [PMID:1315784|PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0008290 F-actin capping protein complex [PMID:14769858]
experiment: EXISTENCE:direct assay:GO:0030479 actin cortical patch [PMID:14769858]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:19053807]
experiment: EXISTENCE:direct assay:GO:0051016 barbed-end actin filament capping [PMID:14769858|PMID:1315784]
experiment: EXISTENCE:mutant phenotype:GO:0008290 F-actin capping protein complex [PMID:14769858]
experiment: EXISTENCE:mutant phenotype:GO:0030447 filamentous growth [PMID:15645503]
experiment: EXISTENCE:mutant phenotype:GO:0051015 actin filament binding [PMID:14769858]
note: Beta subunit of the capping protein heterodimer (Cap1p and Cap2p); capping protein (CP) binds to the barbed ends of actin filaments preventing further polymerization; localized predominantly to cortical actin patches; protein increases in abundance and relocalizes from bud neck to plasma membrane upon DNA replication stress
codon start: 1
product: F-actin-capping protein subunit beta
translation: MSDAQFDAALDLLRRLNPTTLQENLNNLIELQPNLAQDLLSSVDVPLSTQKDSADSNREYLCCDYNRDIDSFRSPWSNTYYPELSPKDLQDSPFPSAPLRKLEILANDSFDVYRDLYYEGGISSVYLWDLNEEDFNGHDFAGVVLFKKNQSDHSNWDSIHVFEVTTSPSSPDSFNYRVTTTIILHLDKTKTDQNSHMMLSGNLTRQTEKDIAIDMSRPLDVIFTSHVANLGSLIEDIESQMRNLLETVYFEKTRDIFHQTKNAAIASSAEEANKDAQAEVIRGLQSL
SIO_010081: YIL034C
subclass of: SO_0000673
so part of: YIL034C
location: complement(289226..290089)
location: region:289226-290089:-1
so has part: feature:289226-290089:-1:exon

NP_012230.3
type: Protein
SIO_000068: ncbiprotein

S000001296
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:289226-290089:-1:exon

YIL033C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SRA1
gene: BCY1
locus tag: YIL033C
gene synonym: SRA1
so part of: sequence
location: complement(<290419..>291669)
location: region:290419-291669:-1
so has part: feature:290419-291669:-1:exon
subclass of: SO_0000010

854778
type: Gene
SIO_000068: ncbigene

position:290419:-1
position: 290419
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:291669:-1
position: 291669
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:290419-291669:-1:exon

YIL033C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SRA1
gene: BCY1
locus tag: YIL033C
gene synonym: SRA1
product: cAMP-dependent protein kinase regulatory subunit BCY1
transcript id: NM_001179383.1
SIO_010081: YIL033C
subclass of: SO_0000673
so part of: YIL033C
location: complement(<290419..>291669)
location: region:290419-291669:-1
so has part: feature:290419-291669:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:290419-291669:-1:exon

YIL033C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SRA1
gene: BCY1
locus tag: YIL033C
gene synonym: SRA1
experiment: EXISTENCE:direct assay:GO:0000785 chromatin [PMID:26403272]
experiment: EXISTENCE:direct assay:GO:0004862 cAMP-dependent protein kinase inhibitor activity [PMID:3037314]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:11134339|PMID:18417610|PMID:11914276|PMID:22842922|P MID:3288487]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11134339|PMID:11914276|PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:2831892]
experiment: EXISTENCE:direct assay:GO:0046580 negative regulation of Ras protein signal transduction [PMID:3037314]
experiment: EXISTENCE:genetic interaction:GO:0045762 positive regulation of adenylate cyclase activity [PMID:2981630|PMID:3891097]
experiment: EXISTENCE:genetic interaction:GO:0097271 protein localization to bud neck [PMID:12782684]
experiment: EXISTENCE:mutant phenotype:GO:0004862 cAMP-dependent protein kinase inhibitor activity [PMID:6292221]
experiment: EXISTENCE:mutant phenotype:GO:0010603 regulation of cytoplasmic mRNA processing body assembly [PMID:21925385]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:26947009]
experiment: EXISTENCE:mutant phenotype:GO:0046580 negative regulation of Ras protein signal transduction [PMID:3037314]
note: Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA); PKA is a component of a signaling pathway that controls a variety of cellular processes, including metabolism, cell cycle, stress response, stationary phase, and sporulation; regulator of meiotic commitment
codon start: 1
product: cAMP-dependent protein kinase regulatory subunit BCY1
translation: MVSSLPKESQAELQLFQNEINAANPSDFLQFSANYFNKRLEQQRAFLKAREPEFKAKNIVLFPEPEESFSRPQSAQSQSRSRSSVMFKSPFVNEDPHSNVFKSGFNLDPHEQDTHQQAQEEQQHTREKTSTPPLPMHFNAQRRTSVSGETLQPNNFDDWTPDHYKEKSEQQLQRLEKSIRNNFLFNKLDSDSKRLVINCLEEKSVPKGATIIKQGDQGDYFYVVEKGTVDFYVNDNKVNSSGPGSSFGELALMYNSPRAATVVATSDCLLWALDRLTFRKILLGSSFKKRLMYDDLLKSMPVLKSLTTYDRAKLADALDTKIYQPGETIIREGDQGENFYLIEYGAVDVSKKGQGVINKLKDHDYFGEVALLNDLPRQATVTATKRTKVATLGKSGFQRLLGPAVDVLKLNDPTRH
SIO_010081: YIL033C
subclass of: SO_0000673
so part of: YIL033C
location: complement(290419..291669)
location: region:290419-291669:-1
so has part: feature:290419-291669:-1:exon

NP_012231.1
type: Protein
SIO_000068: ncbiprotein

S000001295
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:290419-291669:-1:exon

YIL031W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SMT4
gene: ULP2
locus tag: YIL031W
gene synonym: SMT4
so part of: sequence
location: <292633..>295737
location: region:292633-295737:1
so has part: feature:292633-295737:1:exon
subclass of: SO_0000010

854780
type: Gene
SIO_000068: ncbigene

position:292633:1
position: 292633
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:295737:1
position: 295737
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:292633-295737:1:exon

YIL031W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SMT4
gene: ULP2
locus tag: YIL031W
gene synonym: SMT4
product: SUMO protease ULP2
transcript id: NM_001179381.1
SIO_010081: YIL031W
subclass of: SO_0000673
so part of: YIL031W
location: <292633..>295737
location: region:292633-295737:1
so has part: feature:292633-295737:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:292633-295737:1:exon

YIL031W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SMT4
gene: ULP2
locus tag: YIL031W
gene synonym: SMT4
experiment: EXISTENCE:direct assay:GO:0000785 chromatin [PMID:30575729]
experiment: EXISTENCE:direct assay:GO:0003711 transcription elongation factor activity [PMID:31313851]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:10713161]
experiment: EXISTENCE:direct assay:GO:0008234 cysteine-type peptidase activity [PMID:10713161]
experiment: EXISTENCE:direct assay:GO:0016926 protein desumoylation [PMID:10713161]
experiment: EXISTENCE:direct assay:GO:0016929 deSUMOylase activity [PMID:10713161]
experiment: EXISTENCE:mutant phenotype:GO:0006276 plasmid maintenance [PMID:10713161|PMID:11333221]
experiment: EXISTENCE:mutant phenotype:GO:0007094 mitotic spindle assembly checkpoint signaling [PMID:10713162]
experiment: EXISTENCE:mutant phenotype:GO:0016926 protein desumoylation [PMID:10713161]
experiment: EXISTENCE:mutant phenotype:GO:0016929 deSUMOylase activity [PMID:10713161]
experiment: EXISTENCE:mutant phenotype:GO:0030261 chromosome condensation [PMID:11333221]
note: Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins; plays a role in chromosome cohesion at centromeric regions and recovery from checkpoint arrest induced by DNA damage or DNA replication defects; potential Cdc28p substrate; human homolog PML implicated in promyelocytic leukemia can partially complement yeast null mutant
codon start: 1
product: SUMO protease ULP2
translation: MSARKRKFNSLKPLDTLNSSRASSPRSSASLPPKRYNTFRKDPKIVDHLNNASTKDFLPVLSMNSESKRQIELSDNDVDNNDEGEGVNSGCSDQDFEPLQSSPLKRHSSLKSTSNGLLFQMSNNLGNGSPEPAVASTSPNGSIISTKLNLNGQFSCVDSKTLRIYRHKAPCIMTFVSDHNHPKFSLYFQQSVIYNSQVNLLDDVELIILDKKNSFMAIILKDLKKVKMILDVNNSSININTNILIWSTASSASNKKIKSIKRFLLMSYSSSIKVEILDHKEQILERLKHLIHPISSSSPSLNMERAINSTKNAFDSLRLKKTKLSTNDDESPQIHTHFLSNKPHGLQSLTKRTRIASLGKKEHSISVPKSNISPSDFYNTNGTETLQSHAVSQLRRSNRFKDVSDPANSNSNSEFDDATTEFETPELFKPSLCYKFNDGSSYTITNQDFKCLFNKDWVNDSILDFFTKFYIESSIEKSIIKREQVHLMSSFFYTKLISNPADYYSNVKKWVNNTDLFSKKYVVIPINISYHWFSCIITNLDAILDFHQNKDKNDAINSDEISINNPLVNILTFDSLRQTHSREIDPIKEFLISYALDKYSIQLDKTQIKMKTCPVPQQPNMSDCGVHVILNIRKFFENPVETIDVWKNSKIKSKHFTAKMINKYFDKNERNSARKNLRHTLKLLQLNYISYLKKENLYEEVMQMEEKKSTNINNNENYDDDDEEIQIIENIDQSSKDNNAQLTSEPPCSRSSSISTTEREPTELHNSVVRQPTGEIITDNEDPVRAASPETASVSPPIRHNILKSSSPFISESANETEQEEFTSPYFGRPSLKTRAKQFEGVSSPIKNDQALSSTHDIMMPSPKPKRIYPSKKIPQLSSHVQSLSTDSMERQSSPNNTNIVISDTEQDSRLGVNSESKNTSGIVNRDDSDVNLIGSSLPNVAEKNHDNTQESNGNNDSLGKILQNVDKELNEKLVDIDDVAFSSPTRGIPRTSATSKGSNAQLLSNYGDENNQSQDSVWDEGRDNPILLEDEDP
SIO_010081: YIL031W
subclass of: SO_0000673
so part of: YIL031W
location: 292633..295737
location: region:292633-295737:1
so has part: feature:292633-295737:1:exon

NP_012233.1
type: Protein
SIO_000068: ncbiprotein

S000001293
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:292633-295737:1:exon

YIL030C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: DOA10
alternative label: KIS3
gene: SSM4
locus tag: YIL030C
gene synonym: DOA10; KIS3
so part of: sequence
location: complement(<296050..>300009)
location: region:296050-300009:-1
so has part: feature:296050-300009:-1:exon
subclass of: SO_0000010

854781
type: Gene
SIO_000068: ncbigene

position:296050:-1
position: 296050
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:300009:-1
position: 300009
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:296050-300009:-1:exon

YIL030C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: DOA10
alternative label: KIS3
gene: SSM4
locus tag: YIL030C
gene synonym: DOA10; KIS3
product: E3 ubiquitin-protein ligase SSM4
transcript id: NM_001179380.3
SIO_010081: YIL030C
subclass of: SO_0000673
so part of: YIL030C
location: complement(<296050..>300009)
location: region:296050-300009:-1
so has part: feature:296050-300009:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:296050-300009:-1:exon

YIL030C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: DOA10
alternative label: KIS3
gene: SSM4
locus tag: YIL030C
gene synonym: DOA10; KIS3
EC number: 2.3.2.27
experiment: EXISTENCE:direct assay:GO:0000837 Doa10p ubiquitin ligase complex [PMID:16873066]
experiment: EXISTENCE:direct assay:GO:0004842 ubiquitin-protein transferase activity [PMID:11641273]
experiment: EXISTENCE:direct assay:GO:0005635 nuclear envelope [PMID:11641273]
experiment: EXISTENCE:direct assay:GO:0005637 nuclear inner membrane [PMID:17051211]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:11641273]
experiment: EXISTENCE:direct assay:GO:0030970 retrograde protein transport, ER to cytosol [PMID:32588820]
experiment: EXISTENCE:direct assay:GO:0061630 ubiquitin protein ligase activity [PMID:25918226]
experiment: EXISTENCE:mutant phenotype:GO:0030433 ubiquitin-dependent ERAD pathway [PMID:11641273|PMID:15252059]
experiment: EXISTENCE:mutant phenotype:GO:0030970 retrograde protein transport, ER to cytosol [PMID:32588820]
note: Membrane-embedded ubiquitin-protein ligase and retrotranslocase; ER and inner nuclear membrane localized RING-CH domain E3 ligase involved in ER-associated protein degradation (ERAD); aids Cdc48p in the extraction of faulty membrane proteins; targets misfolded cytosolic/nucleoplasmic domains of soluble and membrane embedded proteins (ERAD-C) and Sbh2p, a transmembrane domain-containing substrate (ERAD-M); C-terminal element, conserved in human ortholog MARCH6, determines substrate selectivity
codon start: 1
product: E3 ubiquitin-protein ligase SSM4
translation: MDVDSDVNVSRLRDELHKVANEETDTATFNDDAPSGATCRICRGEATEDNPLFHPCKCRGSIKYMHESCLLEWVASKNIDISKPGADVKCDICHYPIQFKTIYAENMPEKIPFSLLLSKSILTFFEKARLALTIGLAAVLYIIGVPLVWNMFGKLYTMMLDGSSPYPGDFLKSLIYGYDQSATPELTTRAIFYQLLQNHSFTSLQFIMIVILHIALYFQYDMIVREDVFSKMVFHKIGPRLSPKDLKSRLKERFPMMDDRMVEYLAREMRAHDENRQEQGHDRLNMPAAAADNNNNVINPRNDNVPPQDPNDHRNFENLRHVDELDHDEATEEHENNDSDNSLPSGDDSSRILPGSSSDNEEDEEAEGQQQQQQPEEEADYRDHIEPNPIDMWANRRAQNEFDDLIAAQQNAINRPNAPVFIPPPAQNRAGNVDQDEQDFGAAVGVPPAQANPDDQGQGPLVINLKLKLLNVIAYFIIAVVFTAIYLAISYLFPTFIGFGLLKIYFGIFKVILRGLCHLYYLSGAHIAYNGLTKLVPKVDVAMSWISDHLIHDIIYLYNGYTENTMKHSIFIRALPALTTYLTSVSIVCASSNLVSRGYGRENGMSNPTRRLIFQILFALKCTFKVFTLFFIELAGFPILAGVMLDFSLFCPILASNSRMLWVPSICAIWPPFSLFVYWTIGTLYMYWFAKYIGMIRKNIIRPGVLFFIRSPEDPNIKILHDSLIHPMSIQLSRLCLSMFIYAIFIVLGFGFHTRIFFPFMLKSNLLSVPEAYKPTSIISWKFNTILLTLYFTKRILESSSYVKPLLERYWKTIFKLCSRKLRLSSFILGKDTPTERGHIVYRNLFYKYIAAKNAEWSNQELFTKPKTLEQAEELFGQVRDVHAYFVPDGVLMRVPSSDIVSRNYVQTMFVPVTKDDKLLKPLDLERIKERNKRAAGEFGYLDEQNTEYDQYYIVYVPPDFRLRYMTLLGLVWLFASILMLGVTFISQALINFVCSFGFLPVVKLLLGERNKVYVAWKELSDISYSYLNIYYVCVGSVCLSKIAKDILHFTEGQNTLDEHAVDENEVEEVEHDIPERDINNAPVNNINNVEEGQGIFMAIFNSIFDSMLVKYNLMVFIAIMIAVIRTMVSWVVLTDGILACYNYLTIRVFGNSSYTIGNSKWFKYDESLLFVVWIISSMVNFGTGYKSLKLFFRNRNTSKLNFLKTMALELFKQGFLHMVIYVLPIIILSLVFLRDVSTKQIIDISHGSRSFTLSLNESFPTWTRMQDIYFGLLIALESFTFFFQATVLFIQWFKSTVQNVKDEVYTKGRALENLPDES
SIO_010081: YIL030C
subclass of: SO_0000673
so part of: YIL030C
location: complement(296050..300009)
location: region:296050-300009:-1
so has part: feature:296050-300009:-1:exon

NP_012234.3
type: Protein
SIO_000068: ncbiprotein

S000001292
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:296050-300009:-1:exon

YNCI0007C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCI0007C
so part of: sequence
location: complement(300228..300300)
location: region:300228-300300:-1
so has part: feature:300228-300300:-1:exon
subclass of: SO_0000663

854782
type: Gene
SIO_000068: ncbigene

position:300228:-1
position: 300228
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:300300:-1
position: 300300
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:300228-300300:-1:exon

YNCI0007C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCI0007C
product: tRNA-Lys
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:8915539]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:8915539]
experiment: EXISTENCE:mutant phenotype:GO:0030533 triplet codon-amino acid adaptor activity [PMID:17560369]
experiment: EXISTENCE:mutant phenotype:GO:0032543 mitochondrial translation [PMID:17560369]
note: Lysine tRNA (tRNA-Lys), predicted by tRNAscan-SE analysis; a small portion is imported into mitochondria via interaction with mt lysyl-tRNA synthetase Msk1p and is necessary to decode AAG codons at high temperature, when base modification of mt-encoded tRNA-Lys is reduced
SIO_010081: YNCI0007C
subclass of: SO_0000673
so part of: YNCI0007C
location: complement(300228..300300)
location: region:300228-300300:-1
so has part: feature:300228-300300:-1:exon

S000006624
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:300228-300300:-1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(300409..300727)
location: region:300409-300727:-1
so has part: feature:300409-300727:-1:region

S000007013
type: SGD
SIO_000068: sgd

position:300409:-1
position: 300409
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:300727:-1
position: 300727
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:300409-300727:-1:region

YIL029C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: EMA17
locus tag: YIL029C
so part of: sequence
location: complement(<300829..>301257)
location: region:300829-301257:-1
so has part: feature:300829-301257:-1:exon
subclass of: SO_0000010

854783
type: Gene
SIO_000068: ncbigene

position:300829:-1
position: 300829
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:301257:-1
position: 301257
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:300829-301257:-1:exon

YIL029C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: EMA17
locus tag: YIL029C
product: Ema17p
transcript id: NM_001179379.3
SIO_010081: YIL029C
subclass of: SO_0000673
so part of: YIL029C
location: complement(<300829..>301257)
location: region:300829-301257:-1
so has part: feature:300829-301257:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:300829-301257:-1:exon

YIL029C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: EMA17
locus tag: YIL029C
note: Protein involved in targeting mitochondrial membrane protein precursors to mitochondrial translocation system; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO); YIL029C has a paralog, YPR071W, that arose from a single-locus duplication
codon start: 1
product: Ema17p
translation: MRLIFIAKMLQYSFLPFSPFNLLNFDNSISVSWFITYSVIVSIWGFAVWIEGAYRNKINLQLPRCTKIKCSRYNTRIKSPKWFNCKNWMHFFLLYLFLTASNLIVQLAYFSKEMCSQGINVPGTKKPGNRVYLSVIILMGNG
SIO_010081: YIL029C
subclass of: SO_0000673
so part of: YIL029C
location: complement(300829..301257)
location: region:300829-301257:-1
so has part: feature:300829-301257:-1:exon

NP_012235.3
type: Protein
SIO_000068: ncbiprotein

S000001291
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:300829-301257:-1:exon

YIL027C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: KRE27
gene: EMC5
locus tag: YIL027C
gene synonym: KRE27
so part of: sequence
location: complement(<303679..>304104)
location: region:303679-304104:-1
so has part: feature:303679-304104:-1:exon
subclass of: SO_0000010

854785
type: Gene
SIO_000068: ncbigene

position:303679:-1
position: 303679
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:304104:-1
position: 304104
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:303679-304104:-1:exon

YIL027C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: KRE27
gene: EMC5
locus tag: YIL027C
gene synonym: KRE27
product: Emc5p
transcript id: NM_001179377.1
SIO_010081: YIL027C
subclass of: SO_0000673
so part of: YIL027C
location: complement(<303679..>304104)
location: region:303679-304104:-1
so has part: feature:303679-304104:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:303679-304104:-1:exon

YIL027C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: KRE27
gene: EMC5
locus tag: YIL027C
gene synonym: KRE27
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:14562095|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0072546 EMC complex [PMID:19325107]
experiment: EXISTENCE:genetic interaction:GO:0034975 protein folding in endoplasmic reticulum [PMID:19325107]
note: Member of conserved ER transmembrane complex; required for efficient folding of proteins in the ER; null mutant displays induction of the unfolded protein response, and also shows K1 killer toxin resistance; homologous to worm B0334.15/EMC-5, fly CG15168, human MMGT
codon start: 1
product: Emc5p
translation: MSFVSKLLYTVSALVLFHSGFSSYEFHHLLKLNSLNNAQGAISKLPKDIMYETYAGLILFVLAVFTSFEKLQYLPIESNDGKIISQGNYLKEIALNKATNVDNLIGSNPNGEIIFTPSFVDVHMKRKICREWASNTVKKEK
SIO_010081: YIL027C
subclass of: SO_0000673
so part of: YIL027C
location: complement(303679..304104)
location: region:303679-304104:-1
so has part: feature:303679-304104:-1:exon

NP_012237.1
type: Protein
SIO_000068: ncbiprotein

S000001289
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:303679-304104:-1:exon

YIL026C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SCC3
gene: IRR1
locus tag: YIL026C
gene synonym: SCC3
so part of: sequence
location: complement(<304477..>307929)
location: region:304477-307929:-1
so has part: feature:304477-307929:-1:exon
subclass of: SO_0000010

854786
type: Gene
SIO_000068: ncbigene

position:304477:-1
position: 304477
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:307929:-1
position: 307929
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:304477-307929:-1:exon

YIL026C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SCC3
gene: IRR1
locus tag: YIL026C
gene synonym: SCC3
product: Irr1p
transcript id: NM_001179376.1
SIO_010081: YIL026C
subclass of: SO_0000673
so part of: YIL026C
location: complement(<304477..>307929)
location: region:304477-307929:-1
so has part: feature:304477-307929:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:304477-307929:-1:exon

YIL026C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SCC3
gene: IRR1
locus tag: YIL026C
gene synonym: SCC3
experiment: EXISTENCE:direct assay:GO:0003682 chromatin binding [PMID:9990856]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:28077952|PMID:10028182|PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:28077952]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0030892 mitotic cohesin complex [PMID:9990856]
experiment: EXISTENCE:mutant phenotype:GO:0007064 mitotic sister chromatid cohesion [PMID:9990856]
note: Subunit of the cohesin complex; which is required for sister chromatid cohesion during mitosis and meiosis and interacts with centromeres and chromosome arms; relocalizes to the cytosol in response to hypoxia; essential for viability
codon start: 1
product: Irr1p
translation: MTAVRRSTRIRTKSQVIEEDYDDEQNTSAQHVESDKITAKTQHEEEEEQDTGESEESSSEDDYEDQDDDDYVDTATAKRKSRKRKPKSASNTSSKRQKKKPTSAQKSAVSHAPAYHRSKKDQDQYLEIAKDFQPTELFDILSTSEDVSIEELLREWLETYSENRDKFLQEFINLLLNCCGSVARVEDHDVHSNESSNETIGEIQLLFQRQKLHEFYLLISKENKKRKNFKMGPLYQNFAEFMTKLLEVANDLQLLYVESDEDDTQIVTGNLVLDLLTWLSSFSVCKIRCFRYISTLTLYLFQDYLTQQAVNLEKNYLAKLSKQLSLEEKKKRPNNKTLEKLESTIAETQGSKVVIDSIIDNIVKLCFVHRYKDVSDLIRSESMLHLSIWIKNYPEYFLKVTFLKYFGWLLSDNSVSVRLQVTKILPHLIIQNHNSKSTDNSAIRQVFERFKTKILEVAIRDVNLDVRIHSIQVLTEASSLGYLDDSEILIISSLMFDEEFDPFKTSSFNKRSKFLSTVAKFLARVIKEKFDEFIKTHEDLPKEVDGLEVGPVVQVGIFIKILNDSLIYHLKDCAEVDSRTKIRMLTQAAEFLSPYISTHLKTICNLLISDTESNELIQKLQNSANNNSDDEDVDDEELDITPLFPIDRNSTILYLNVFHGLCAGANNPKIQTKDSVKEIVLPLFYDLLNAASIESADILCPLLESFITFSLDDWISIGYETELKKITDKTIKAFMDSTIGNSKVDMKYDIFAKFIHHIHHFEKKELQEKFLNQIATLKIHLKKFLQEKMDPNNSRDDYKDLTCSLYELYINKLTILGRDYPIEVDEELLQLFLNNFVSRIPIMFQDFDDSTAQEINFKMLVLLATWNLEKWREIIEKVRDYENSISKDLRSVWKPIAAIIGRLNTLVISLAATNETFENINSLFYLKWSACTSLMDIIVAIKIFELKLPADATTWRYSMSEQFPFYLHDNASKVLLKIFLYLESLFAKQVDVQLERVADEDANLNDLPETGFFENIETEFLLFTVKLKGLMKLNILDERFASRVALNKEKLGPLFKKIVDDTIMENPEPNKKNIQKAKSNQTQREKAPLQPNSERETDHANTENNDPDIPMTIDLEPIEESSQNNSELAPIEEHPTVVDAIDNSDEITQD
SIO_010081: YIL026C
subclass of: SO_0000673
so part of: YIL026C
location: complement(304477..307929)
location: region:304477-307929:-1
so has part: feature:304477-307929:-1:exon

NP_012238.1
type: Protein
SIO_000068: ncbiprotein

S000001288
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:304477-307929:-1:exon

YIL024C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YIL024C
so part of: sequence
location: complement(<308602..>309171)
location: region:308602-309171:-1
so has part: feature:308602-309171:-1:exon
subclass of: SO_0000010

854788
type: Gene
SIO_000068: ncbigene

position:308602:-1
position: 308602
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:309171:-1
position: 309171
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:308602-309171:-1:exon

YIL024C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YIL024C
product: uncharacterized protein
transcript id: NM_001179374.3
SIO_010081: YIL024C
subclass of: SO_0000673
so part of: YIL024C
location: complement(<308602..>309171)
location: region:308602-309171:-1
so has part: feature:308602-309171:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:308602-309171:-1:exon

YIL024C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YIL024C
note: hypothetical protein; non-essential gene; expression directly regulated by the metabolic and meiotic transcriptional regulator Ume6p
codon start: 1
product: uncharacterized protein
translation: MSNFLLVIPEDVIKGCSKADKLVVTGEFDNWRHSDYVLQYDGSTQNYRVQIPRRKGQRSTMFKVVINDKKWVTLNYFDTVTDKSGYTNNILHFKDNEASQLMDIPLSPHTRSNTAKGKPEDDSLNDYVNLSSHSDLSSTEEIVCWNSDMEDENMDATIQCDFHQAFNSRKESLNGLMCIAKKVKTYWNK
SIO_010081: YIL024C
subclass of: SO_0000673
so part of: YIL024C
location: complement(308602..309171)
location: region:308602-309171:-1
so has part: feature:308602-309171:-1:exon

NP_012240.3
type: Protein
SIO_000068: ncbiprotein

S000001286
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:308602-309171:-1:exon

YIL023C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: YKE4
locus tag: YIL023C
so part of: sequence
location: complement(<309386..>310426)
location: region:309386-310426:-1
so has part: feature:309386-310426:-1:exon
subclass of: SO_0000010

854789
type: Gene
SIO_000068: ncbigene

position:309386:-1
position: 309386
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:310426:-1
position: 310426
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:309386-310426:-1:exon

YIL023C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: YKE4
locus tag: YIL023C
product: Zn(2+) transporter YKE4
transcript id: NM_001179373.1
SIO_010081: YIL023C
subclass of: SO_0000673
so part of: YIL023C
location: complement(<309386..>310426)
location: region:309386-310426:-1
so has part: feature:309386-310426:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:309386-310426:-1:exon

YIL023C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: YKE4
locus tag: YIL023C
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:16760462|PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0005385 zinc ion transmembrane transporter activity [PMID:16760462]
experiment: EXISTENCE:mutant phenotype:GO:0006829 zinc ion transport [PMID:16760462]
note: Zinc transporter; localizes to the ER; null mutant is sensitive to calcofluor white, leads to zinc accumulation in cytosol; ortholog of the mouse KE4 and member of the ZIP (ZRT, IRT-like Protein) family
codon start: 1
product: Zn(2+) transporter YKE4
translation: MKASHICSYLLSIAPLVVSHGVHHNRDHGHEANHESKQSFLILKQESIFYSLVCFLQNHLFVLGPRYNAIVAILIIQLMPCLFVLFVPGLRKNDRASLTLSLLVSFSLGTLLGDILLHVIPESLSGVTDVTMVGGAIFLGFISFLTLDKTMRILSGTSNDDGSIHSHSHSHTPQQTAEKKAGFNMSAYLNVISGIAHHITDGIALATSFYSSTQVGIMTSIAVTFHEIPHELGDFAILLSSGFTFPQAIRAQAVTAFGAVVGTSIGCWMNEIGNNSHKATSSSANASELMLPFTAGGLIYIATTSVVPQILHSSAPDSKLREFKKWALQLVFIFVGFAVMALMDEH
SIO_010081: YIL023C
subclass of: SO_0000673
so part of: YIL023C
location: complement(309386..310426)
location: region:309386-310426:-1
so has part: feature:309386-310426:-1:exon

NP_012241.1
type: Protein
SIO_000068: ncbiprotein

S000001285
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:309386-310426:-1:exon

YIL022W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ISP45
alternative label: MIM44
alternative label: MPI1
gene: TIM44
locus tag: YIL022W
gene synonym: ISP45; MIM44; MPI1
so part of: sequence
location: <311165..>312460
location: region:311165-312460:1
so has part: feature:311165-312460:1:exon
subclass of: SO_0000010

854790
type: Gene
SIO_000068: ncbigene

position:311165:1
position: 311165
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:312460:1
position: 312460
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:311165-312460:1:exon

YIL022W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ISP45
alternative label: MIM44
alternative label: MPI1
gene: TIM44
locus tag: YIL022W
gene synonym: ISP45; MIM44; MPI1
product: protein translocase subunit TIM44
transcript id: NM_001179372.1
SIO_010081: YIL022W
subclass of: SO_0000673
so part of: YIL022W
location: <311165..>312460
location: region:311165-312460:1
so has part: feature:311165-312460:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:311165-312460:1:exon

YIL022W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ISP45
alternative label: MIM44
alternative label: MPI1
gene: TIM44
locus tag: YIL022W
gene synonym: ISP45; MIM44; MPI1
experiment: EXISTENCE:direct assay:GO:0001405 PAM complex, Tim23 associated import motor [PMID:14517234|PMID:14638855]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:mutant phenotype:GO:0030150 protein import into mitochondrial matrix [PMID:1396562|PMID:18400944]
experiment: EXISTENCE:mutant phenotype:GO:0030674 protein-macromolecule adaptor activity [PMID:10824101|PMID:11344168]
experiment: EXISTENCE:mutant phenotype:GO:0051087 chaperone binding [PMID:11344168]
experiment: EXISTENCE:physical interaction:GO:0051087 chaperone binding [PMID:7809127]
note: Essential component of the TIM23 complex; tethers the import motor and regulatory factors (PAM complex) to the translocation channel (Tim23p-Tim17p core complex); TIM23 complex is short for the translocase of the inner mitochondrial membrane
codon start: 1
product: protein translocase subunit TIM44
translation: MHRSTFIRTSGTSSRTLTARYRSQYTGLLVARVLFSTSTTRAQGGNPRSPLQIFRDTFKKEWEKSQELQENIKTLQDASGKLGESEAYKKAREAYLKAQRGSTIVGKTLKKTGETMEHIATKAWESELGKNTRKAAAATAKKLDESFEPVRQTKIYKEVSEVIDDGESSRYGGFITKEQRRLKRERDLASGKRHRAVKSNEDAGTAVVATNIESKESFGKKVEDFKEKTVVGRSIQSLKNKLWDESENPLIVVMRKITNKVGGFFAETESSRVYSQFKLMDPTFSNESFTRHLREYIVPEILEAYVKGDVKVLKKWFSEAPFNVYAAQQKIFKEQDVYADGRILDIRGVEIVSAKLLAPQDIPVLVVGCRAQEINLYRKKKTGEIAAGDEANILMSSYAMVFTRDPEQIDDDETEGWKILEFVRGGSRQFT
SIO_010081: YIL022W
subclass of: SO_0000673
so part of: YIL022W
location: 311165..312460
location: region:311165-312460:1
so has part: feature:311165-312460:1:exon

NP_012242.1
type: Protein
SIO_000068: ncbiprotein

S000001284
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:311165-312460:1:exon

YIL021W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RPB3
locus tag: YIL021W
so part of: sequence
location: <312905..>313861
location: region:312905-313861:1
so has part: feature:312905-313861:1:exon
subclass of: SO_0000010

854791
type: Gene
SIO_000068: ncbigene

position:312905:1
position: 312905
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:313861:1
position: 313861
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:312905-313861:1:exon

YIL021W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RPB3
locus tag: YIL021W
product: DNA-directed RNA polymerase II core subunit RPB3
transcript id: NM_001179371.3
SIO_010081: YIL021W
subclass of: SO_0000673
so part of: YIL021W
location: <312905..>313861
location: region:312905-313861:1
so has part: feature:312905-313861:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:312905-313861:1:exon

YIL021W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RPB3
locus tag: YIL021W
experiment: EXISTENCE:direct assay:GO:0001055 RNA polymerase II activity [PMID:8288647]
experiment: EXISTENCE:direct assay:GO:0003968 RNA-dependent RNA polymerase activity [PMID:18004386]
experiment: EXISTENCE:direct assay:GO:0005654 nucleoplasm [PMID:15520468]
experiment: EXISTENCE:direct assay:GO:0005665 RNA polymerase II, core complex [PMID:1331084|PMID:2186966|PMID:2183013]
experiment: EXISTENCE:mutant phenotype:GO:0006366 transcription by RNA polymerase II [PMID:2685562]
experiment: EXISTENCE:mutant phenotype:GO:0006369 termination of RNA polymerase II transcription [PMID:16537912]
note: RNA polymerase II third largest subunit B44; part of central core; similar to prokaryotic alpha subunit
codon start: 1
product: DNA-directed RNA polymerase II core subunit RPB3
translation: MSEEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIVSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYDPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVDQVVVRGIDTLQKKVASILLALTQMDQDKVNFASGDNNTASNMLGSNEDVMMTGAEQDPYSNASQMGNTGSGGYDNAW
SIO_010081: YIL021W
subclass of: SO_0000673
so part of: YIL021W
location: 312905..313861
location: region:312905-313861:1
so has part: feature:312905-313861:1:exon

NP_012243.3
type: Protein
SIO_000068: ncbiprotein

S000001283
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:312905-313861:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS918; Putative replication origin; identified in multiple array studies, not yet confirmed by plasmid-based assay
so part of: sequence
location: 313861..314035
location: region:313861-314035:1
so has part: feature:313861-314035:1:region

S000130160
type: SGD
SIO_000068: sgd

position:314035:1
position: 314035
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:313861-314035:1:region

YIL020C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HIS6
locus tag: YIL020C
so part of: sequence
location: complement(<314035..>314820)
location: region:314035-314820:-1
so has part: feature:314035-314820:-1:exon
subclass of: SO_0000010

854792
type: Gene
SIO_000068: ncbigene

position:314035:-1
position: 314035
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:314820:-1
position: 314820
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:314035-314820:-1:exon

YIL020C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HIS6
locus tag: YIL020C
product: 1-(5-phosphoribosyl)-5- ((5-phosphoribosylamino)methylideneamino)imidazole-4- carboxamide isomerase HIS6
transcript id: NM_001179370.3
SIO_010081: YIL020C
subclass of: SO_0000673
so part of: YIL020C
location: complement(<314035..>314820)
location: region:314035-314820:-1
so has part: feature:314035-314820:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:314035-314820:-1:exon

YIL020C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: HIS6
locus tag: YIL020C
EC number: 5.3.1.16
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:genetic interaction:GO:0000105 histidine biosynthetic process [PMID:9332345]
experiment: EXISTENCE:genetic interaction:GO:0003949 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase activity [PMID:9332345]
experiment: EXISTENCE:mutant phenotype:GO:0000105 histidine biosynthetic process [PMID:14190241|PMID:9332345]
note: Enzyme that catalyzes the fourth step in the histidine pathway; Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts
codon start: 1
product: 1-(5-phosphoribosyl)-5- ((5-phosphoribosylamino)methylideneamino)imidazole-4- carboxamide isomerase HIS6
translation: MTKFIGCIDLHNGEVKQIVGGTLTSKKEDVPKTNFVSQHPSSYYAKLYKDRDVQGCHVIKLGPNNDDAAREALQESPQFLQVGGGINDTNCLEWLKWASKVIVTSWLFTKEGHFQLKRLERLTELCGKDRIVVDLSCRKTQDGRWIVAMNKWQTLTDLELNADTFRELRKYTNEFLIHAADVEGLCGGIDELLVSKLFEWTKDYDDLKIVYAGGAKSVDDLKLVDELSHGKVDLTFGSSLDIFGGNLVKFEDCCRWNEKQG
SIO_010081: YIL020C
subclass of: SO_0000673
so part of: YIL020C
location: complement(314035..314820)
location: region:314035-314820:-1
so has part: feature:314035-314820:-1:exon

NP_012244.3
type: Protein
SIO_000068: ncbiprotein

S000001282
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:314035-314820:-1:exon

YIL019W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FAF1
locus tag: YIL019W
so part of: sequence
location: <315093..>316133
location: region:315093-316133:1
so has part: feature:315093-316133:1:exon
subclass of: SO_0000010

854793
type: Gene
SIO_000068: ncbigene

position:315093:1
position: 315093
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:316133:1
position: 316133
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:315093-316133:1:exon

YIL019W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FAF1
locus tag: YIL019W
product: Faf1p
transcript id: NM_001179369.1
SIO_010081: YIL019W
subclass of: SO_0000673
so part of: YIL019W
location: <315093..>316133
location: region:315093-316133:1
so has part: feature:315093-316133:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:315093-316133:1:exon

YIL019W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FAF1
locus tag: YIL019W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:15078877|PMID:15178413]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:15078877|PMID:15178413]
note: Protein required for pre-rRNA processing; also required for 40S ribosomal subunit assembly
codon start: 1
product: Faf1p
translation: MTLDDDDYIKQMELQRKAFESQFGSLESMGFEDKTKNIRTEVDTRDSSGDEIDNSDHGSDFKDGTIESSNSSDEDSGNETAEENNQDSKPKTQPKVIRFNGPSDVYVPPSKKTQKLLRSGKTLTQINKKLESTEAKEEKEDETLEAENLQNDLELQQFLRESHLLSAFNNGGSGSTNSGVSLTLQSMGGGNDDGIVYQDDQVIGKARSRTLEMRLNRLSRVNGHQDKINKLEKVPMHIRRGMIDKHVKRIKKYEQEAAEGGIVLSKVKKGQFRKIESTYKKDIERRIGGSIKARDKEKATKRERGLKISSVGRSTRNGLIVSKRDIARISGGERSGKFNGKKKSRR
SIO_010081: YIL019W
subclass of: SO_0000673
so part of: YIL019W
location: 315093..316133
location: region:315093-316133:1
so has part: feature:315093-316133:1:exon

NP_012245.1
type: Protein
SIO_000068: ncbiprotein

S000001281
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:315093-316133:1:exon

YIL018W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LOT2
alternative label: RPL5A
gene: RPL2B
locus tag: YIL018W
gene synonym: LOT2; RPL5A
so part of: sequence
location: <316768..>317932
location: region:316768-317932:1
so has part: feature:316768-317932:1:exon
subclass of: SO_0000010

854794
type: Gene
SIO_000068: ncbigene

position:316768:1
position: 316768
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:317932:1
position: 317932
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:316768-317932:1:exon

YIL018W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LOT2
alternative label: RPL5A
gene: RPL2B
locus tag: YIL018W
gene synonym: LOT2; RPL5A
product: ribosomal 60S subunit protein L2B
transcript id: NM_001179368.1
SIO_010081: YIL018W
subclass of: SO_0000673
so part of: YIL018W
location: join(<316768..316771,317172..>317932)
location: region:316768-317932:1
so has part: feature:316768-316771:1:exon
so has part: feature:317172-317932:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:316768-316771:1:exon

position:316771:1
position: 316771
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:317172-317932:1:exon

position:317172:1
position: 317172
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YIL018W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LOT2
alternative label: RPL5A
gene: RPL2B
locus tag: YIL018W
gene synonym: LOT2; RPL5A
experiment: EXISTENCE:direct assay:GO:0002181 cytoplasmic translation [PMID:18782943]
experiment: EXISTENCE:direct assay:GO:0003735 structural constituent of ribosome [PMID:18782943]
experiment: EXISTENCE:direct assay:GO:0022625 cytosolic large ribosomal subunit [PMID:18782943]
note: Ribosomal 60S subunit protein L2B; homologous to mammalian ribosomal protein L2 and bacterial L2; RPL2B has a paralog, RPL2A, that arose from the whole genome duplication; expression is upregulated at low temperatures
codon start: 1
product: ribosomal 60S subunit protein L2B
translation: MGRVIRNQRKGAGSIFTSHTRLRQGAAKLRTLDYAERHGYIRGIVKQIVHDSGRGAPLAKVVFRDPYKYRLREEIFIANEGVHTGQFIYAGKKASLNVGNVLPLGSVPEGTIVSNVEEKPGDRGALARASGNYVIIIGHNPDENKTRVRLPSGAKKVISSDARGVIGVIAGGGRVDKPLLKAGRAFHKYRLKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRGAVSGQKAGLIAARRTGLLRGSQKTQD
SIO_010081: YIL018W
subclass of: SO_0000673
so part of: YIL018W
location: join(316768..316771,317172..317932)
location: region:316768-317932:1
so has part: feature:316768-316771:1:exon
so has part: feature:317172-317932:1:exon

NP_012246.1
type: Protein
SIO_000068: ncbiprotein

S000001280
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:316768-316771:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:317172-317932:1:exon

YIL017C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: GID5
alternative label: YIL017W
gene: VID28
locus tag: YIL017C
gene synonym: GID5; YIL017W
so part of: sequence
location: complement(<318200..>320965)
location: region:318200-320965:-1
so has part: feature:318200-320965:-1:exon
subclass of: SO_0000010

854795
type: Gene
SIO_000068: ncbigene

position:318200:-1
position: 318200
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:320965:-1
position: 320965
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:318200-320965:-1:exon

YIL017C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: GID5
alternative label: YIL017W
gene: VID28
locus tag: YIL017C
gene synonym: GID5; YIL017W
product: glucose-induced degradation complex subunit VID28
transcript id: NM_001179367.3
SIO_010081: YIL017C
subclass of: SO_0000673
so part of: YIL017C
location: complement(<318200..>320965)
location: region:318200-320965:-1
so has part: feature:318200-320965:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:318200-320965:-1:exon

YIL017C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: GID5
alternative label: YIL017W
gene: VID28
locus tag: YIL017C
gene synonym: GID5; YIL017W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0034657 GID complex [PMID:16872538|PMID:18508925]
experiment: EXISTENCE:mutant phenotype:GO:0007039 protein catabolic process in the vacuole [PMID:15358789]
experiment: EXISTENCE:mutant phenotype:GO:0030437 ascospore formation [PMID:12586695]
experiment: EXISTENCE:mutant phenotype:GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process [PMID:12686616|PMID:15358789]
experiment: EXISTENCE:mutant phenotype:GO:0045721 negative regulation of gluconeogenesis [PMID:12686616]
note: GID Complex subunit, serves as adaptor for regulatory subunit Vid24p; protein involved in proteasome-dependent catabolite degradation of fructose-1,6-bisphosphatase (FBPase); localized to the nucleus and the cytoplasm
codon start: 1
product: glucose-induced degradation complex subunit VID28
translation: MTVAYSLENLKKISNSLVGDQLAKVDYFLAPKCQIFQCLLSIEQSDGVELKNAKLDLLYTLLHLEPQQRDIVGTYYFDIVSAIYKSMSLASSFTKNNSSTNYKYIKLLNLCAGVYPNCGFPDLQYLQNGFIQLVNHKFLRSKCKIDEVVTIIELLKLFLLVDEKNCSDFNKSKFMEEEREVTETSHYQDFKMAESLEHIIVKISSKYLDQISLKYIVRLKVSRPASPSSVKNDPFDNKGVDCTRAIPKKINISNMYDSSLLSLALLLYLRYHYMIPGDRKLRNDATFKMFVLGLLKSNDVNIRCVALKFLLQPYFTEDKKWEDTRTLEKILPYLVKSFNYDPLPWWFDPFDMLDSLIVLYNEITPMNNPVLTTLAHTNVIFCILSRFAQCLSLPQHNEATLKTTTKFIKICASFAASDEKYRLLLLNDTLLLNHLEYGLESHITLIQDFISLKDEIKETTTESHSMCLPPIYDHDFVAAWLLLLKSFSRSVSALRTTLKRNKIAQLLLQILSKTYTLTKECYFAGQDFMKPEIMIMGITLGSICNFVVEFSNLQSFMLRNGIIDIIEKMLTDPLFNSKKAWDDNEDERRIALQGIPVHEVKANSLWVLRHLMYNCQNEEKFQLLAKIPMNLILDFINDPCWAVQAQCFQLLRNLTCNSRKIVNILLEKFKDVEYKIDPQTGNKISIGSTYLFEFLAKKMRLLNPLDTQQKKAMEGILYIIVNLAAVNENKKQLVIEQDEILNIMSEILVETTTDSSSNGNDSNLKLACLWVLNNLLWNSSVSHYTQYAIENGLEPGHSPSDSENPQSTVTIGYNESVAGGYSRGKYYDEPDGDDSSSNANDDEDDDNDEGDDEGDEFVRTPAAKGSTSNVQVTRATVERCRKLVEVGLYDLVRKNITDESLSVREKARTLLYHMDLLLKVK
SIO_010081: YIL017C
subclass of: SO_0000673
so part of: YIL017C
location: complement(318200..320965)
location: region:318200-320965:-1
so has part: feature:318200-320965:-1:exon

NP_012247.3
type: Protein
SIO_000068: ncbiprotein

S000001279
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:318200-320965:-1:exon

YIL016W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SNL1
locus tag: YIL016W
so part of: sequence
location: <321454..>321933
location: region:321454-321933:1
so has part: feature:321454-321933:1:exon
subclass of: SO_0000010

854796
type: Gene
SIO_000068: ncbigene

position:321454:1
position: 321454
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:321933:1
position: 321933
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:321454-321933:1:exon

YIL016W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SNL1
locus tag: YIL016W
product: Snl1p
transcript id: NM_001179366.1
SIO_010081: YIL016W
subclass of: SO_0000673
so part of: YIL016W
location: <321454..>321933
location: region:321454-321933:1
so has part: feature:321454-321933:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:321454-321933:1:exon

YIL016W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SNL1
locus tag: YIL016W
experiment: EXISTENCE:direct assay:GO:0005635 nuclear envelope [PMID:9450961]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:9450961]
experiment: EXISTENCE:direct assay:GO:0043022 ribosome binding [PMID:22635919]
experiment: EXISTENCE:genetic interaction:GO:0006999 nuclear pore organization [PMID:9450961]
experiment: EXISTENCE:physical interaction:GO:0006457 protein folding [PMID:12105220]
note: Ribosome-associated protein; proposed to act in protein synthesis, nuclear pore complex biogenesis and maintenance as well as protein folding and prion maintenance; has similarity to the mammalian BAG-1 protein
codon start: 1
product: Snl1p
translation: MSHNAMEHWKSKLSKTSTSTYVLLAVIAVVFLVTIRRPNGSKGKSSKKRASKKNKKGKNQFEKAPVPLTLEEQIDNVSLRYGNELEGRSKDLINRFDVEDEKDIYERNYCNEMLLKLLIELDSIDLINVDESLRRPLKEKRKGVIKEIQAMLKSLDSLK
SIO_010081: YIL016W
subclass of: SO_0000673
so part of: YIL016W
location: 321454..321933
location: region:321454-321933:1
so has part: feature:321454-321933:1:exon

NP_012248.1
type: Protein
SIO_000068: ncbiprotein

S000001278
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:321454-321933:1:exon

YIL015W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SST1
gene: BAR1
locus tag: YIL015W
gene synonym: SST1
so part of: sequence
location: <322342..>324105
location: region:322342-324105:1
so has part: feature:322342-324105:1:exon
subclass of: SO_0000010

854797
type: Gene
SIO_000068: ncbigene

position:322342:1
position: 322342
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:324105:1
position: 324105
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:322342-324105:1:exon

YIL015W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SST1
gene: BAR1
locus tag: YIL015W
gene synonym: SST1
product: aspartyl protease BAR1
transcript id: NM_001179365.1
SIO_010081: YIL015W
subclass of: SO_0000673
so part of: YIL015W
location: <322342..>324105
location: region:322342-324105:1
so has part: feature:322342-324105:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:322342-324105:1:exon

YIL015W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SST1
gene: BAR1
locus tag: YIL015W
gene synonym: SST1
EC number: 3.4.23.35
experiment: EXISTENCE:direct assay:GO:0000754 adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion [PMID:6345506]
experiment: EXISTENCE:direct assay:GO:0004190 aspartic-type endopeptidase activity [PMID:9249020]
experiment: EXISTENCE:direct assay:GO:0005576 extracellular region [PMID:3124102]
experiment: EXISTENCE:direct assay:GO:0009277 fungal-type cell wall [PMID:10438739]
experiment: EXISTENCE:direct assay:GO:0043171 peptide catabolic process [PMID:9249020]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0000754 adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion [PMID:7050666]
note: Aspartyl protease secreted to periplasmic space of mating type a cell; helps cells monitor availability of mating partners; cleaves and inactivates alpha factor allowing cells to recover from alpha-factor-induced cell cycle arrest
codon start: 1
product: aspartyl protease BAR1
translation: MSAINHLCLKLILASFAIINTITALTNDGTGHLEFLLQHEEEMYYATTLDIGTPSQSLTVLFDTGSADFWVMDSSNPFCLPNSNTSSYSNATYNGEEVKPSIDCRSMSTYNEHRSSTYQYLENGRFYITYADGTFADGSWGTETVSINGIDIPNIQFGVAKYATTPVSGVLGIGFPRRESVKGYEGAPNEYYPNFPQILKSEKIIDVVAYSLFLNSPDSGTGSIVFGAIDESKFSGDLFTFPMVNEYPTIVDAPATLAMTIQGLGAQNKSSCEHETFTTTKYPVLLDSGTSLLNAPKVIADKMASFVNASYSEEEGIYILDCPVSVGDVEYNFDFGDLQISVPLSSLILSPETEGSYCGFAVQPTNDSMVLGDVFLSSAYVVFDLDNYKISLAQANWNASEVSKKLVNIQTDGSISGAKIATAEPWSTNEPFTVTSDIYSSTGCKSRPFLQSSTASSLIAETNVQSRNCSTKMPGTRSTTVLSKPTQNSAMHQSTGAVTQTSNETKLELSSTMANSGSVSLPTSNSIDKEFEHSKSQTTSDPSVAEHSTFNQTFVHETKYRPTHKTVITETVTKYSTVLINVCKPTY
SIO_010081: YIL015W
subclass of: SO_0000673
so part of: YIL015W
location: 322342..324105
location: region:322342-324105:1
so has part: feature:322342-324105:1:exon

NP_012249.1
type: Protein
SIO_000068: ncbiprotein

S000001277
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:322342-324105:1:exon

YNCI0008C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCI0008C
so part of: sequence
location: complement(324303..324374)
location: region:324303-324374:-1
so has part: feature:324303-324374:-1:exon
subclass of: SO_0000663

854798
type: Gene
SIO_000068: ncbigene

position:324303:-1
position: 324303
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:324374:-1
position: 324374
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:324303-324374:-1:exon

YNCI0008C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCI0008C
product: tRNA-Asp
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Aspartate tRNA (tRNA-Asp), predicted by tRNAscan-SE analysis
SIO_010081: YNCI0008C
subclass of: SO_0000673
so part of: YNCI0008C
location: complement(324303..324374)
location: region:324303-324374:-1
so has part: feature:324303-324374:-1:exon

S000006534
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:324303-324374:-1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty3 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 324391..324734
location: region:324391-324734:1
so has part: feature:324391-324734:1:region

S000007019
type: SGD
SIO_000068: sgd

position:324391:1
position: 324391
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:324734:1
position: 324734
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:324391-324734:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 324831..325164
location: region:324831-325164:1
so has part: feature:324831-325164:1:region

S000007016
type: SGD
SIO_000068: sgd

position:324831:1
position: 324831
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:325164:1
position: 325164
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:324831-325164:1:region

YIL014C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YIL015C-A
locus tag: YIL014C-A
gene synonym: YIL015C-A
so part of: sequence
location: complement(<325212..>325526)
location: region:325212-325526:-1
so has part: feature:325212-325526:-1:exon
subclass of: SO_0000010

854799
type: Gene
SIO_000068: ncbigene

position:325212:-1
position: 325212
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:325526:-1
position: 325526
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:325212-325526:-1:exon

YIL014C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YIL015C-A
locus tag: YIL014C-A
gene synonym: YIL015C-A
product: uncharacterized protein
transcript id: NM_001181433.3
SIO_010081: YIL014C-A
subclass of: SO_0000673
so part of: YIL014C-A
location: complement(<325212..>325526)
location: region:325212-325526:-1
so has part: feature:325212-325526:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:325212-325526:-1:exon

YIL014C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YIL015C-A
locus tag: YIL014C-A
gene synonym: YIL015C-A
note: hypothetical protein; null mutant shows improved incorporation efficiency of noncanonical amino acids in place of amber stop codon
codon start: 1
product: uncharacterized protein
translation: MDIDMNYPSITTLMSNESANLLIIWGNATPDISYLSYTTNPMLGDYVLNVSAINGCTEELIATHLVPTLENATQWVYDAGEYWDNYSFTDESTPLPGLSWPFNE
SIO_010081: YIL014C-A
subclass of: SO_0000673
so part of: YIL014C-A
location: complement(325212..325526)
location: region:325212-325526:-1
so has part: feature:325212-325526:-1:exon

NP_012250.3
type: Protein
SIO_000068: ncbiprotein

S000003536
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:325212-325526:-1:exon

YNCI0009W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCI0009W
so part of: sequence
location: 325748..325820
location: region:325748-325820:1
so has part: feature:325748-325820:1:exon
subclass of: SO_0000663

854800
type: Gene
SIO_000068: ncbigene

position:325748:1
position: 325748
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:325820:1
position: 325820
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:325748-325820:1:exon

YNCI0009W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCI0009W
product: tRNA-Thr
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Threonine tRNA (tRNA-Thr), predicted by tRNAscan-SE analysis
SIO_010081: YNCI0009W
subclass of: SO_0000673
so part of: YNCI0009W
location: 325748..325820
location: region:325748-325820:1
so has part: feature:325748-325820:1:exon

S000006742
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:325748-325820:1:exon

YIL014W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MNT3
locus tag: YIL014W
so part of: sequence
location: <326103..>327995
location: region:326103-327995:1
so has part: feature:326103-327995:1:exon
subclass of: SO_0000010

854801
type: Gene
SIO_000068: ncbigene

position:326103:1
position: 326103
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:327995:1
position: 327995
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:326103-327995:1:exon

YIL014W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MNT3
locus tag: YIL014W
product: alpha-1,3-mannosyltransferase MNT3
transcript id: NM_001179364.3
SIO_010081: YIL014W
subclass of: SO_0000673
so part of: YIL014W
location: <326103..>327995
location: region:326103-327995:1
so has part: feature:326103-327995:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:326103-327995:1:exon

YIL014W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MNT3
locus tag: YIL014W
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005794 Golgi apparatus [PMID:30700649]
experiment: EXISTENCE:genetic interaction:GO:0000033 alpha-1,3-mannosyltransferase activity [PMID:10521541]
experiment: EXISTENCE:genetic interaction:GO:0006493 protein O-linked glycosylation [PMID:10521541]
experiment: EXISTENCE:mutant phenotype:GO:0000033 alpha-1,3-mannosyltransferase activity [PMID:10521541]
experiment: EXISTENCE:mutant phenotype:GO:0006493 protein O-linked glycosylation [PMID:10521541]
note: Alpha-1,3-mannosyltransferase; adds the fourth and fifth alpha-1,3-linked mannose residues to O-linked glycans during protein O-glycosylation
codon start: 1
product: alpha-1,3-mannosyltransferase MNT3
translation: MLKSLKSRRLILKRLVTLLLSLFFSYLIFSASRNVTSSNKLNNHASERTAVESSAFNWIEKRQHQVRSENLMNRLSAYFLPFLSRSSHKERVLLRQLGNNEIAKSDKCRYIFEVLYKIDPDWDNAQTAKFYNVDGVDNTLASLLGERLRSYDYCFLSGQLDPTAIFANSTVNPHDLQNRMFPFLKKINEESKTVMWPIITDMTTGEAVPAPEVDMESSNFNGNFWSNWNRLSKGRGFVLTIAEKDVPLFLKQLKVMEFSKNELPFQIVSTGNELSAESIAKISETAKETEQRVYLVDCSTVLDTNFANTYISFFQNKWVATLFNTFEEYILLDADVVPFVGSDYFFDSPSYRESGILLFKDRVMENEQTFQYCIEMLNEVEPSAQERRFIGSRLVFDSSLPFSSETSEEASVYYNFFKKLRLHHVDSGLVVVNKLEKLNGLLMSFMLNLDGKLQRCVYGDKEIFWLGQLYAGQDYSINPVDGSIIGPVNEEPENDDGHKSGMYYICSTQIAHSDSKNRLLWVNGGLKTCKISNSAEDDFGREPEYFKSRYGDISKLKRIYDASLNVEGLIVPDVSVHPWMQIKECSNYMYCAYATGDGHTNSELDEGRLITFTEKELRYINDISRTWNAN
SIO_010081: YIL014W
subclass of: SO_0000673
so part of: YIL014W
location: 326103..327995
location: region:326103-327995:1
so has part: feature:326103-327995:1:exon

NP_012251.3
type: Protein
SIO_000068: ncbiprotein

S000001276
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:326103-327995:1:exon

YIL013C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PDR11
locus tag: YIL013C
so part of: sequence
location: complement(<328207..>332442)
location: region:328207-332442:-1
so has part: feature:328207-332442:-1:exon
subclass of: SO_0000010

854802
type: Gene
SIO_000068: ncbigene

position:328207:-1
position: 328207
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:332442:-1
position: 332442
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:328207-332442:-1:exon

YIL013C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PDR11
locus tag: YIL013C
product: ATP-binding cassette multidrug transporter PDR11
transcript id: NM_001179363.1
SIO_010081: YIL013C
subclass of: SO_0000673
so part of: YIL013C
location: complement(<328207..>332442)
location: region:328207-332442:-1
so has part: feature:328207-332442:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:328207-332442:-1:exon

YIL013C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PDR11
locus tag: YIL013C
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:33375075]
experiment: EXISTENCE:direct assay:GO:0042626 ATPase-coupled transmembrane transporter activity [PMID:28922409]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0035376 sterol import [PMID:12077145|PMID:21110944]
experiment: EXISTENCE:mutant phenotype:GO:0035376 sterol import [PMID:12077145]
experiment: EXISTENCE:mutant phenotype:GO:0042626 ATPase-coupled transmembrane transporter activity [PMID:28922409]
note: ATP-binding cassette (ABC) transporter; multidrug transporter involved in multiple drug resistance; mediates sterol uptake when sterol biosynthesis is compromised; regulated by Pdr1p; required for anaerobic growth; PDR11 has a paralog, AUS1, that arose from the whole genome duplication
codon start: 1
product: ATP-binding cassette multidrug transporter PDR11
translation: MSLSKYFNPIPDASVTFDGATVQLEESLGAVQNDEESASEFKNVGHLEISDITFRANEGEVVLVLGNPTSALFKGLFHGHKHLKYSPEGSIRFKDNEYKQFASKCPHQIIYNNEQDIHFPYLTVEQTIDFALSCKFHIPKQERIEMRDELLKEFGLSHVKKTYVGNDYVRGVSGGERKRISIIETFIANGSVYLWDNSTKGLDSATALEFLSITQKMAKATRSVNFVKISQASDKIVSKFDKILMLGDSFQVFYGTMEECLTHFHDTLQIKKNPNDCIIEYLTSILNFKFKETSNSIVGLDTPSVVSEENQALNINNETDLHTLWIQSPYYKHWKAITSKTVQECTRKDVNPDDISPIFSIPLKTQLKTCTVRAFERIIGDRNYLISQFVSVVVQSLVIGSLFYNIPLTTIGSFSRGSLTFFSILFFTFLSLADMPASFQRQPVVRKHVQLHFYYNWVETLATNFFDCCSKFILVVIFTIILYFLAHLQYNAARFFIFLLFLSVYNFCMVSLFALTALIAPTLSMANLLAGILLLAIAMYASYVIYMKDMHPWFIWIAYLNPAMFAMEAILSNELFNLKLDCHESIIPRGEYYDNISFSHKACAWQGATLGNDYVRGRDYLKSGLKYTYHHVWRNFGIIIGFLCFFLFCSLLAAEYITPLFTRENLLRWNNYLKRYCPFLNSQKKNNKSAITNNDGVCTPKTPIANFSTSSSSVPSVSHQYDTDYNIKHPDETVNNHTKESVAMETQKHVISWKNINYTIGDKKLINDASGYISSGLTALMGESGAGKTTLLNVLSQRTESGVVTGELLIDGQPLTNIDAFRRSIGFVQQQDVHLELLTVRESLEISCVLRGDGDRDYLGVVSNLLRLPSEKLVADLSPTQRKLLSIGVELVTKPSLLLFLDEPTSGLDAEAALTIVQFLKKLSMQGQAILCTIHQPSKSVISYFDNIYLLKRGGECVYFGSLPNACDYFVAHDRRLTFDREMDNPADFVIDVVGSGSTNIPMDDAEKPTSSKIDEPVSYHKQSDSINWAELWQSSPEKVRVADDLLLLEEEARKSGVDFTTSVWSPPSYMEQIKLITKRQYICTKRDMTYVFAKYALNAGAGLFIGFSFWRTKHNINGLQDAIFLCFMMLCVSSPLINQVQDKALQSKEVYIAREARSNTYHWTVLLIAQTIVELPLAISSSTLFFLCCYFCCGFETSARVAGVFYLNYILFSMYYLSFGLWLLYSAPDLQTAAVFVAFLYSFTASFCGVMQPYSLFPRFWTFMYRVSPYTYFIETFVSLLLHDREVNCSTSEMVPSQPVMGQTCGQFMKPFIDEFGGKLHINNTYTVCAYCMYTVGDDFLAQENMSYHHRWRNFGFEWVFVCFNIAAMFVGFYLTYIKKIWPSVIDGIKKCIPSMRRSKTSHNPNEQSV
SIO_010081: YIL013C
subclass of: SO_0000673
so part of: YIL013C
location: complement(328207..332442)
location: region:328207-332442:-1
so has part: feature:328207-332442:-1:exon

NP_012252.1
type: Protein
SIO_000068: ncbiprotein

S000001275
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:328207-332442:-1:exon

YIL012W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YIL012W
so part of: sequence
location: <333011..>333352
location: region:333011-333352:1
so has part: feature:333011-333352:1:exon
subclass of: SO_0000010

854803
type: Gene
SIO_000068: ncbigene

position:333011:1
position: 333011
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:333352:1
position: 333352
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:333011-333352:1:exon

YIL012W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YIL012W
product: uncharacterized protein
transcript id: NM_001348845.1
SIO_010081: YIL012W
subclass of: SO_0000673
so part of: YIL012W
location: <333011..>333352
location: region:333011-333352:1
so has part: feature:333011-333352:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:333011-333352:1:exon

YIL012W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YIL012W
note: hypothetical protein; conserved across S. cerevisiae strains
codon start: 1
product: uncharacterized protein
translation: MCLGKLYFEQLILVRCIKGRQSGNITTGESRCVSWNVYCTTSMIGLFSWRKMLLFQHFSYTQRENRQIGGKTWSLISSLFHLNETLASALHHPYETLALYEAYFALREKKFLL
SIO_010081: YIL012W
subclass of: SO_0000673
so part of: YIL012W
location: 333011..333352
location: region:333011-333352:1
so has part: feature:333011-333352:1:exon

NP_001335785.1
type: Protein
SIO_000068: ncbiprotein

S000001274
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:333011-333352:1:exon

YIL011W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YIB1
gene: TIR3
locus tag: YIL011W
gene synonym: YIB1
so part of: sequence
location: <333727..>334536
location: region:333727-334536:1
so has part: feature:333727-334536:1:exon
subclass of: SO_0000010

854804
type: Gene
SIO_000068: ncbigene

position:333727:1
position: 333727
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:334536:1
position: 334536
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:333727-334536:1:exon

YIL011W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YIB1
gene: TIR3
locus tag: YIL011W
gene synonym: YIB1
product: Tir3p
transcript id: NM_001179361.1
SIO_010081: YIL011W
subclass of: SO_0000673
so part of: YIL011W
location: <333727..>334536
location: region:333727-334536:1
so has part: feature:333727-334536:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:333727-334536:1:exon

YIL011W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YIB1
gene: TIR3
locus tag: YIL011W
gene synonym: YIB1
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0009277 fungal-type cell wall [PMID:10383953]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
note: Cell wall mannoprotein; member of Srp1p/Tip1p family of serine-alanine-rich proteins; expressed under anaerobic conditions and required for anaerobic growth; TIR3 has a paralog, TIR2, that arose from the whole genome duplication
codon start: 1
product: Tir3p
translation: MSFTKIAALLAVAAASTQLVSAEVGQYEIVEFDAILADVKANLEQYMSLAMNNPDFTLPSGVLDVYQHMTTATDDSYTSYFTEMDFAQITTAMVQVPWYSSRLEPEIIAALQSAGISITSLGQTVSESGSESATASSDASSASESSSAASSSASESSSAASSSASESSSAASSSASESSSAASSSASEAAKSSSSAKSSGSSAASSAASSASSKASSAASSSAKASSSAEKSTNSSSSATSKNAGAAMDMGFFSAGVGAAIAGAAAMLL
SIO_010081: YIL011W
subclass of: SO_0000673
so part of: YIL011W
location: 333727..334536
location: region:333727-334536:1
so has part: feature:333727-334536:1:exon

NP_012254.1
type: Protein
SIO_000068: ncbiprotein

S000001273
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:333727-334536:1:exon

YIL010W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: DOT5
locus tag: YIL010W
so part of: sequence
location: <334882..>335529
location: region:334882-335529:1
so has part: feature:334882-335529:1:exon
subclass of: SO_0000010

854805
type: Gene
SIO_000068: ncbigene

position:334882:1
position: 334882
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:335529:1
position: 335529
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:334882-335529:1:exon

YIL010W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: DOT5
locus tag: YIL010W
product: thioredoxin peroxidase DOT5
transcript id: NM_001179360.3
SIO_010081: YIL010W
subclass of: SO_0000673
so part of: YIL010W
location: <334882..>335529
location: region:334882-335529:1
so has part: feature:334882-335529:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:334882-335529:1:exon

YIL010W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: DOT5
locus tag: YIL010W
EC number: 1.11.1.24
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:2408019|PMID:10681558]
experiment: EXISTENCE:direct assay:GO:0008379 thioredoxin peroxidase activity [PMID:10681558]
experiment: EXISTENCE:direct assay:GO:0045454 cell redox homeostasis [PMID:10681558]
experiment: EXISTENCE:genetic interaction:GO:0034599 cellular response to oxidative stress [PMID:15051715]
experiment: EXISTENCE:mutant phenotype:GO:0008379 thioredoxin peroxidase activity [PMID:10681558]
experiment: EXISTENCE:mutant phenotype:GO:0045454 cell redox homeostasis [PMID:10681558]
note: Nuclear thiol peroxidase; functions as an alkyl-hydroperoxide reductase during post-diauxic growth
codon start: 1
product: thioredoxin peroxidase DOT5
translation: MGEALRRSTRIAISKRMLEEEESKLAPISTPEVPKKKIKTGPKHNANQAVVQEANRSSDVNELEIGDPIPDLSLLNEDNDSISLKKITENNRVVVFFVYPRASTPGCTRQACGFRDNYQELKKYAAVFGLSADSVTSQKKFQSKQNLPYHLLSDPKREFIGLLGAKKTPLSGSIRSHFIFVDGKLKFKRVKISPEVSVNDAKKEVLEVAEKFKEE
SIO_010081: YIL010W
subclass of: SO_0000673
so part of: YIL010W
location: 334882..335529
location: region:334882-335529:1
so has part: feature:334882-335529:1:exon

NP_012255.3
type: Protein
SIO_000068: ncbiprotein

S000001272
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:334882-335529:1:exon

YIL009C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: EST3
locus tag: YIL009C-A
so part of: sequence
location: complement(<335666..>336212)
location: region:335666-336212:-1
so has part: feature:335666-336212:-1:exon
subclass of: SO_0000010

854806
type: Gene
SIO_000068: ncbigene

position:335666:-1
position: 335666
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:336212:-1
position: 336212
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:335666-336212:-1:exon

YIL009C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: EST3
locus tag: YIL009C-A
product: telomerase subunit EST3
transcript id: NM_001184306.2
SIO_010081: YIL009C-A
subclass of: SO_0000673
so part of: YIL009C-A
location: complement(<335666..>336212)
location: region:335666-336212:-1
so has part: feature:335666-336212:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:335666-336212:-1:exon

YIL009C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: EST3
locus tag: YIL009C-A
experiment: EXISTENCE:direct assay:GO:0003924 GTPase activity [PMID:20884318]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:12101098]
experiment: EXISTENCE:direct assay:GO:0005697 telomerase holoenzyme complex [PMID:10898986]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0007004 telomere maintenance via telomerase [PMID:10898986]
experiment: EXISTENCE:direct assay:GO:0033677 DNA/RNA helicase activity [PMID:16884717]
experiment: EXISTENCE:direct assay:GO:0042162 telomeric DNA binding [PMID:16884717]
experiment: EXISTENCE:mutant phenotype:GO:0003924 GTPase activity [PMID:20884318]
experiment: EXISTENCE:mutant phenotype:GO:0007004 telomere maintenance via telomerase [PMID:8978029]
ribosomal slippage: true
note: Component of the telomerase holoenzyme; involved in telomere replication; synthesis of the full-length protein results from a programmed +1 ribosomal frameshift
codon start: 1
product: telomerase subunit EST3
translation: MPKVILESHSKPTDSVFLQPWIKALIEDNSEHDQYHPSGHVIPSLTKQDLALPHMSPTILTNPCHFAKITKFYNVCDYKVYASIRDSSHQILVEFSQECVSNFERTHNCRITSETTNCLMIIGDADLVYVTNSRAMSHFKICLSNISSKEIVPVLNVNQATIFDIDQVGSLSTFPFVYKYL
SIO_010081: YIL009C-A
subclass of: SO_0000673
so part of: YIL009C-A
location: complement(join(335666..335935,335937..336212))
location: region:335666-336212:-1
so has part: feature:335937-336212:-1:exon
so has part: feature:335666-335935:-1:exon

NP_012256.1
type: Protein
SIO_000068: ncbiprotein

S000006432
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:335937-336212:-1:exon

position:335937:-1
position: 335937
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:335666-335935:-1:exon

position:335935:-1
position: 335935
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YNCI0010C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCI0010C
so part of: sequence
location: complement(336349..336420)
location: region:336349-336420:-1
so has part: feature:336349-336420:-1:exon
subclass of: SO_0000663

854807
type: Gene
SIO_000068: ncbigene

position:336349:-1
position: 336349
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:336420:-1
position: 336420
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:336349-336420:-1:exon

YNCI0010C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCI0010C
product: tRNA-Asp
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Aspartate tRNA (tRNA-Asp), predicted by tRNAscan-SE analysis
SIO_010081: YNCI0010C
subclass of: SO_0000673
so part of: YNCI0010C
location: complement(336349..336420)
location: region:336349-336420:-1
so has part: feature:336349-336420:-1:exon

S000006535
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:336349-336420:-1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(336708..336897)
location: region:336708-336897:-1
so has part: feature:336708-336897:-1:region

S000007014
type: SGD
SIO_000068: sgd

position:336708:-1
position: 336708
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:336897:-1
position: 336897
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:336708-336897:-1:region

YIL009W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FAA3
locus tag: YIL009W
so part of: sequence
location: <339344..>341428
location: region:339344-341428:1
so has part: feature:339344-341428:1:exon
subclass of: SO_0000010

854808
type: Gene
SIO_000068: ncbigene

position:339344:1
position: 339344
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:341428:1
position: 341428
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:339344-341428:1:exon

YIL009W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FAA3
locus tag: YIL009W
product: long-chain fatty acid-CoA ligase FAA3
transcript id: NM_001179359.1
SIO_010081: YIL009W
subclass of: SO_0000673
so part of: YIL009W
location: <339344..>341428
location: region:339344-341428:1
so has part: feature:339344-341428:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:339344-341428:1:exon

YIL009W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FAA3
locus tag: YIL009W
EC number: 6.2.1.3
experiment: EXISTENCE:direct assay:GO:0004467 long-chain fatty acid-CoA ligase activity [PMID:8206942]
experiment: EXISTENCE:direct assay:GO:0031957 very long-chain fatty acid-CoA ligase activity [PMID:8206942]
experiment: EXISTENCE:genetic interaction:GO:0001676 long-chain fatty acid metabolic process [PMID:7962057]
note: Long chain fatty acyl-CoA synthetase; activates imported fatty acids with a preference for C16:0-C18:0 chain lengths; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
codon start: 1
product: long-chain fatty acid-CoA ligase FAA3
translation: MSEQHSVAVGKAANEHETAPRRNVRVKKRPLIRPLNSSASTLYEFALECFNKGGKRDGMAWRDVIEIHETKKTIVRKVDGKDKSIEKTWLYYEMSPYKMMTYQELIWVMHDMGRGLAKIGIKPNGEHKFHIFASTSHKWMKIFLGCISQGIPVVTAYDTLGESGLIHSMVETESAAIFTDNQLLAKMIVPLQSAKDIKFLIHNEPIDPNDRRQNGKLYKAAKDAINKIREVRPDIKIYSFEEVVKIGKKSKDEVKLHPPEPKDLACIMYTSGSISAPKGVVLTHYNIVSGIAGVGHNVFGWIGSTDRVLSFLPLAHIFELVFEFEAFYWNGILGYGSVKTLTNTSTRNCKGDLVEFKPTIMIGVAAVWETVRKAILEKISDLTPVLQKIFWSAYSMKEKSVPCTGFLSRMVFKKVRQATGGHLKYIMNGGSAISIDAQKFFSIVLCPMIIGYGLTETVANACVLEPDHFEYGIVGDLVGSVTAKLVDVKDLGYYAKNNQGELLLKGAPVCSEYYKNPIETAVSFTYDGWFRTGDIVEWTPKGQLKIIDRRKNLVKTLNGEYIALEKLESVYRSNSYVKNICVYADESRVKPVGIVVPNPGPLSKFAVKLRIMKKGEDIENYIHDKALRNAVFKEMIATAKSQGLVGIELLCGIVFFDEEWTPENGFVTSAQKLKRREILAAVKSEVERVYKENS
SIO_010081: YIL009W
subclass of: SO_0000673
so part of: YIL009W
location: 339344..341428
location: region:339344-341428:1
so has part: feature:339344-341428:1:exon

NP_012257.1
type: Protein
SIO_000068: ncbiprotein

S000001271
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:339344-341428:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS919; Autonomously Replicating Sequence
so part of: sequence
location: 341976..342045
location: region:341976-342045:1
so has part: feature:341976-342045:1:region

S000118398
type: SGD
SIO_000068: sgd

position:341976:1
position: 341976
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:342045:1
position: 342045
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:341976-342045:1:region

YIL008W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: URM1
locus tag: YIL008W
so part of: sequence
location: <342536..>342835
location: region:342536-342835:1
so has part: feature:342536-342835:1:exon
subclass of: SO_0000010

854809
type: Gene
SIO_000068: ncbigene

position:342536:1
position: 342536
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:342835:1
position: 342835
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:342536-342835:1:exon

YIL008W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: URM1
locus tag: YIL008W
product: ubiquitin-related modifier URM1
transcript id: NM_001179358.3
SIO_010081: YIL008W
subclass of: SO_0000673
so part of: YIL008W
location: <342536..>342835
location: region:342536-342835:1
so has part: feature:342536-342835:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:342536-342835:1:exon

YIL008W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: URM1
locus tag: YIL008W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14551258|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0031386 protein tag [PMID:14551258|PMID:10713047]
experiment: EXISTENCE:direct assay:GO:0032447 protein urmylation [PMID:10713047|PMID:14555475]
experiment: EXISTENCE:direct assay:GO:0034599 cellular response to oxidative stress [PMID:21209336]
experiment: EXISTENCE:genetic interaction:GO:0001403 invasive growth in response to glucose limitation [PMID:14551258]
experiment: EXISTENCE:genetic interaction:GO:0007114 cell budding [PMID:14551258]
experiment: EXISTENCE:mutant phenotype:GO:0001403 invasive growth in response to glucose limitation [PMID:14551258]
experiment: EXISTENCE:mutant phenotype:GO:0002098 tRNA wobble uridine modification [PMID:18755837]
experiment: EXISTENCE:mutant phenotype:GO:0002143 tRNA wobble position uridine thiolation [PMID:19145231|PMID:18664566|PMID:19151091]
experiment: EXISTENCE:mutant phenotype:GO:0031386 protein tag [PMID:14551258]
experiment: EXISTENCE:mutant phenotype:GO:0032447 protein urmylation [PMID:14555475]
experiment: EXISTENCE:mutant phenotype:GO:0034599 cellular response to oxidative stress [PMID:14555475]
note: Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs; receives sulfur from the E1-like enzyme Uba4p and transfers it to tRNA; also functions as a protein tag with roles in nutrient sensing and oxidative stress response
codon start: 1
product: ubiquitin-related modifier URM1
translation: MVNVKVEFLGGLDAIFGKQRVHKIKMDKEDPVTVGDLIDHIVSTMINNPNDVSIFIEDDSIRPGIITLINDTDWELEGEKDYILEDGDIISFTSTLHGG
SIO_010081: YIL008W
subclass of: SO_0000673
so part of: YIL008W
location: 342536..342835
location: region:342536-342835:1
so has part: feature:342536-342835:1:exon

NP_012258.3
type: Protein
SIO_000068: ncbiprotein

S000001270
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:342536-342835:1:exon

YIL007C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: NAS2
locus tag: YIL007C
so part of: sequence
location: complement(<342994..>343656)
location: region:342994-343656:-1
so has part: feature:342994-343656:-1:exon
subclass of: SO_0000010

854810
type: Gene
SIO_000068: ncbigene

position:342994:-1
position: 342994
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:343656:-1
position: 343656
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:342994-343656:-1:exon

YIL007C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: NAS2
locus tag: YIL007C
product: Nas2p
transcript id: NM_001179357.3
SIO_010081: YIL007C
subclass of: SO_0000673
so part of: YIL007C
location: complement(<342994..>343656)
location: region:342994-343656:-1
so has part: feature:342994-343656:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:342994-343656:-1:exon

YIL007C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: NAS2
locus tag: YIL007C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:19446323]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11489916]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:19446323]
experiment: EXISTENCE:direct assay:GO:0070682 proteasome regulatory particle assembly [PMID:19446322]
experiment: EXISTENCE:genetic interaction:GO:0070682 proteasome regulatory particle assembly [PMID:19446322|PMID:19446323]
experiment: EXISTENCE:mutant phenotype:GO:0070682 proteasome regulatory particle assembly [PMID:19446322|PMID:19446323]
note: Evolutionarily conserved 19S regulatory particle assembly-chaperone; involved in assembly of the base subcomplex of the 19S proteasomal regulatory particle (RP); non-essential gene; interacts with Rpn4p; protein abundance increases in response to DNA replication stress; ortholog of human p27
codon start: 1
product: Nas2p
translation: MEEEELSKLLANVKIDPSLTSRISQIDSFKLSELMVLKTDIETQLEAYFSVLEQQGIGMDSALVTPDGYPRSDVDVLQVTMIRKNVNMLKNDLNHLLQRSHVLLNQHFDNMNVKSNQDARRNNDDQAIQYTIPFAFISEVVPGSPSDKADIKVDDKLISIGNVHAANHSKLQNIQMVVMKNEDRPLPVLLLREGQILKTSLTPSRNWNGRGLLGCRIQEL
SIO_010081: YIL007C
subclass of: SO_0000673
so part of: YIL007C
location: complement(342994..343656)
location: region:342994-343656:-1
so has part: feature:342994-343656:-1:exon

NP_012259.3
type: Protein
SIO_000068: ncbiprotein

S000001269
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:342994-343656:-1:exon

YIL006W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: NDT1
gene: YIA6
locus tag: YIL006W
gene synonym: NDT1
so part of: sequence
location: <344062..>345183
location: region:344062-345183:1
so has part: feature:344062-345183:1:exon
subclass of: SO_0000010

854811
type: Gene
SIO_000068: ncbigene

position:344062:1
position: 344062
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:345183:1
position: 345183
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:344062-345183:1:exon

YIL006W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: NDT1
gene: YIA6
locus tag: YIL006W
gene synonym: NDT1
product: NAD+ transporter
transcript id: NM_001179356.1
SIO_010081: YIL006W
subclass of: SO_0000673
so part of: YIL006W
location: <344062..>345183
location: region:344062-345183:1
so has part: feature:344062-345183:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:344062-345183:1:exon

YIL006W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: NDT1
gene: YIA6
locus tag: YIL006W
gene synonym: NDT1
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16291748|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0035352 NAD transmembrane transport [PMID:16291748]
experiment: EXISTENCE:direct assay:GO:0051724 NAD transmembrane transporter activity [PMID:16291748]
experiment: EXISTENCE:genetic interaction:GO:0035352 NAD transmembrane transport [PMID:16291748]
experiment: EXISTENCE:genetic interaction:GO:0051724 NAD transmembrane transporter activity [PMID:16291748]
experiment: EXISTENCE:mutant phenotype:GO:0005477 pyruvate secondary active transmembrane transporter activity [PMID:12887330]
experiment: EXISTENCE:mutant phenotype:GO:0006850 mitochondrial pyruvate transmembrane transport [PMID:12887330]
experiment: EXISTENCE:mutant phenotype:GO:0035352 NAD transmembrane transport [PMID:16291748]
experiment: EXISTENCE:mutant phenotype:GO:0051724 NAD transmembrane transporter activity [PMID:16291748]
note: Mitochondrial NAD+ transporter; involved in the transport of NAD+ into the mitochondria (see also YEA6); member of the mitochondrial carrier subfamily; disputed role as a pyruvate transporter; has putative mouse and human orthologs; YIA6 has a paralog, YEA6, that arose from the whole genome duplication; human NAD+ transporter MCART1/SLC25A51 functionally complements the yia6 yea6 double null mutant, and yeast YIA6 reciprocally complements defects in MCART1/SLC25A51 null cells
codon start: 1
product: NAD+ transporter
translation: MTQTDNPVPNCGLLPEQQYCSADHEEPLLLHEEQLIFPDHSSQLSSADIIEPIKMNSSTESIIGTTLRKKWVPLSSTQITALSGAFAGFLSGVAVCPLDVAKTRLQAQGLQTRFENPYYRGIMGTLSTIVRDEGPRGLYKGLVPIVLGYFPTWMIYFSVYEFSKKFFHGIFPQFDFVAQSCAAITAGAASTTLTNPIWVVKTRLMLQSNLGEHPTHYKGTFDAFRKLFYQEGFKALYAGLVPSLLGLFHVAIHFPIYEDLKVRFHCYSRENNTNSINLQRLIMASSVSKMIASAVTYPHEILRTRMQLKSDIPDSIQRRLFPLIKATYAQEGLKGFYSGFTTNLVRTIPASAITLVSFEYFRNRLENISTMVI
SIO_010081: YIL006W
subclass of: SO_0000673
so part of: YIL006W
location: 344062..345183
location: region:344062-345183:1
so has part: feature:344062-345183:1:exon

NP_012260.1
type: Protein
SIO_000068: ncbiprotein

S000001268
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:344062-345183:1:exon

YIL005W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: EPS1
locus tag: YIL005W
so part of: sequence
location: <345692..>347797
location: region:345692-347797:1
so has part: feature:345692-347797:1:exon
subclass of: SO_0000010

854812
type: Gene
SIO_000068: ncbigene

position:345692:1
position: 345692
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:347797:1
position: 347797
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:345692-347797:1:exon

YIL005W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: EPS1
locus tag: YIL005W
product: protein disulfide isomerase EPS1
transcript id: NM_001179355.1
SIO_010081: YIL005W
subclass of: SO_0000673
so part of: YIL005W
location: <345692..>347797
location: region:345692-347797:1
so has part: feature:345692-347797:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:345692-347797:1:exon

YIL005W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: EPS1
locus tag: YIL005W
EC number: 5.3.4.1
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:10545109]
experiment: EXISTENCE:direct assay:GO:0019153 protein-disulfide reductase (glutathione) activity [PMID:16002399]
experiment: EXISTENCE:direct assay:GO:0051082 unfolded protein binding [PMID:16002399]
experiment: EXISTENCE:mutant phenotype:GO:0003756 protein disulfide isomerase activity [PMID:11157982]
experiment: EXISTENCE:mutant phenotype:GO:0006621 protein retention in ER lumen [PMID:10545109]
experiment: EXISTENCE:mutant phenotype:GO:0030433 ubiquitin-dependent ERAD pathway [PMID:12881414]
experiment: EXISTENCE:physical interaction:GO:0005515 protein binding [PMID:16002399]
note: ER protein with chaperone and co-chaperone activity; involved in retention of resident ER proteins; has a role in recognizing proteins targeted for ER-associated degradation (ERAD), member of the protein disulfide isomerase family
codon start: 1
product: protein disulfide isomerase EPS1
translation: MKMNLKRLVVTFFSCITFLLKFTIAAAEPPEGFPEPLNPTNFKEELSKGLHIIDFYSPYCPHCKHLAPVWMETWEEFKEESKTLNITFSQVNCIESADLCGDENIEYFPEIRLYNPSGYIKSFTETPRTKESLIAFARRESMDPNNLDTDLDSAKSESQYLEGFDFLELIAGKATRPHLVSFWPTKDMKNSDDSLEFKNCDKCHEFQRTWKIISRQLAVDDINTGHVNCESNPTICEELGFGDLVKITNHRADREPKVALVLPNKTSNNLFDYPNGYSAKSDGYVDFARRTFTNSKFPNITEGELEKKANRDIDFLQERGRVTNNDIHLVFSYDPETVVIEDFDILEYLIEPLSKIPNIYLHQIDKNLINLSRNLFGRMYEKINYDASQTQKVFNKEYFTMNTVTQLPTFFMFKDGDPISYVFPGYSTTEMRNIDAIMDWVKKYSNPLVTEVDSSNLKKLISFQTKSYSDLAIQLISSTDHKHIKGSNKLIKNLLLASWEYEHIRMENNFEEINERRARKADGIKKIKEKKAPANKIVDKMREEIPHMDQKKLLLGYLDISKEKNFFRKYGITGEYKIGDVIIIDKSNNYYYNKDNFGNSLTSNNPQLLREAFVSLNIPSKALYSSKLKGRLINSPFHNVLSFLDIIHGNGMPGYLIVIVLFIAILKGPSIYRRYKVRKHYRAKRNAVGILGNMEKKKNQD
SIO_010081: YIL005W
subclass of: SO_0000673
so part of: YIL005W
location: 345692..347797
location: region:345692-347797:1
so has part: feature:345692-347797:1:exon

NP_012261.1
type: Protein
SIO_000068: ncbiprotein

S000001267
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:345692-347797:1:exon

YIL004C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SLY12
gene: BET1
locus tag: YIL004C
gene synonym: SLY12
so part of: sequence
location: complement(<347946..>348505)
location: region:347946-348505:-1
so has part: feature:347946-348505:-1:exon
subclass of: SO_0000010

854813
type: Gene
SIO_000068: ncbigene

position:347946:-1
position: 347946
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:348505:-1
position: 348505
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:347946-348505:-1:exon

YIL004C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SLY12
gene: BET1
locus tag: YIL004C
gene synonym: SLY12
product: Bet1p
transcript id: NM_001179354.3
SIO_010081: YIL004C
subclass of: SO_0000673
so part of: YIL004C
location: complement(join(<347946..348363,348495..>348505))
location: region:347946-348505:-1
so has part: feature:348495-348505:-1:exon
so has part: feature:347946-348363:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:348495-348505:-1:exon

position:348495:-1
position: 348495
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:347946-348363:-1:exon

position:348363:-1
position: 348363
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YIL004C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SLY12
gene: BET1
locus tag: YIL004C
gene synonym: SLY12
experiment: EXISTENCE:direct assay:GO:0005484 SNAP receptor activity [PMID:11001058]
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:1396561]
experiment: EXISTENCE:direct assay:GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [PMID:9813082]
experiment: EXISTENCE:direct assay:GO:0006906 vesicle fusion [PMID:11001046]
experiment: EXISTENCE:direct assay:GO:0016020 membrane [PMID:1396561]
experiment: EXISTENCE:direct assay:GO:0030134 COPII-coated ER to Golgi transport vesicle [PMID:11157978]
experiment: EXISTENCE:direct assay:GO:0031201 SNARE complex [PMID:11001058]
experiment: EXISTENCE:mutant phenotype:GO:0005484 SNAP receptor activity [PMID:3312234]
experiment: EXISTENCE:mutant phenotype:GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport [PMID:3312234]
note: Type II membrane protein required for vesicular transport; required for vesicular transport between the endoplasmic reticulum and Golgi complex; v-SNARE with similarity to synaptobrevins
codon start: 1
product: Bet1p
translation: MSSRFAGGNAYQRDTGRTQLFGPADGSNSLDDNVSSALGSTDKLDYSQSTLASLESQSEEQMGAMGQRIKALKSLSLKMGDEIRGSNQTIDQLGDTFHNTSVKLKRTFGNMMEMARRSGISIKTWLIIFFMVGVLFFWVWIT
SIO_010081: YIL004C
subclass of: SO_0000673
so part of: YIL004C
location: complement(join(347946..348363,348495..348505))
location: region:347946-348505:-1
so has part: feature:348495-348505:-1:exon
so has part: feature:347946-348363:-1:exon

NP_012262.3
type: Protein
SIO_000068: ncbiprotein

S000001266
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:348495-348505:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:347946-348363:-1:exon

YIL003W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: DRE3
gene: CFD1
locus tag: YIL003W
gene synonym: DRE3
so part of: sequence
location: <349122..>350003
location: region:349122-350003:1
so has part: feature:349122-350003:1:exon
subclass of: SO_0000010

854814
type: Gene
SIO_000068: ncbigene

position:349122:1
position: 349122
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:350003:1
position: 350003
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:349122-350003:1:exon

YIL003W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: DRE3
gene: CFD1
locus tag: YIL003W
gene synonym: DRE3
product: iron-sulfur cluster assembly protein CFD1
transcript id: NM_001179353.1
SIO_010081: YIL003W
subclass of: SO_0000673
so part of: YIL003W
location: <349122..>350003
location: region:349122-350003:1
so has part: feature:349122-350003:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:349122-350003:1:exon

YIL003W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: DRE3
gene: CFD1
locus tag: YIL003W
gene synonym: DRE3
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:12970194]
experiment: EXISTENCE:direct assay:GO:0016226 iron-sulfur cluster assembly [PMID:17401378]
experiment: EXISTENCE:direct assay:GO:0016887 ATP hydrolysis activity [PMID:26195633]
experiment: EXISTENCE:direct assay:GO:0051539 4 iron, 4 sulfur cluster binding [PMID:17401378]
experiment: EXISTENCE:direct assay:GO:1904564 Nbp35-Cfd1 ATPase complex [PMID:26195633]
experiment: EXISTENCE:mutant phenotype:GO:0002098 tRNA wobble uridine modification [PMID:18755837]
experiment: EXISTENCE:mutant phenotype:GO:0016226 iron-sulfur cluster assembly [PMID:12970194]
note: Highly conserved iron-sulfur cluster binding protein; localized in the cytoplasm; forms a complex with Nbp35p that is involved in iron-sulfur protein assembly in the cytosol
codon start: 1
product: iron-sulfur cluster assembly protein CFD1
translation: MEEQEIGVPAASLAGIKHIILILSGKGGVGKSSVTTQTALTLCSMGFKVGVLDIDLTGPSLPRMFGLENESIYQGPEGWQPVKVETNSTGSLSVISLGFLLGDRGNSVIWRGPKKTSMIKQFISDVAWGELDYLLIDTPPGTSDEHISIAEELRYSKPDGGIVVTTPQSVATADVKKEINFCKKVDLKILGIIENMSGFVCPHCAECTNIFSSGGGKRLSEQFSVPYLGNVPIDPKFVEMIENQVSSKKTLVEMYRESSLCPIFEEIMKKLRKQDTTTPVVDKHEQPQIESPK
SIO_010081: YIL003W
subclass of: SO_0000673
so part of: YIL003W
location: 349122..350003
location: region:349122-350003:1
so has part: feature:349122-350003:1:exon

NP_012263.1
type: Protein
SIO_000068: ncbiprotein

S000001265
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:349122-350003:1:exon

YIL002W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CMI7
locus tag: YIL002W-A
so part of: sequence
location: <350301..>350510
location: region:350301-350510:1
so has part: feature:350301-350510:1:exon
subclass of: SO_0000010

1466493
type: Gene
SIO_000068: ncbigene

position:350301:1
position: 350301
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:350510:1
position: 350510
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:350301-350510:1:exon

YIL002W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CMI7
locus tag: YIL002W-A
product: Cmi7p
transcript id: NM_001184653.1
SIO_010081: YIL002W-A
subclass of: SO_0000673
so part of: YIL002W-A
location: <350301..>350510
location: region:350301-350510:1
so has part: feature:350301-350510:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:350301-350510:1:exon

YIL002W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CMI7
locus tag: YIL002W-A
note: Putative mitochondrial hypothetical protein; identified by expression profiling and mass spectrometry
codon start: 1
product: Cmi7p
translation: MTRDTPEDVSTAGAKDILDVLNLLKGGEEKISEVELKLDEMEKKMDSLLVQLEDLHRDNNDLAKSSSQK
SIO_010081: YIL002W-A
subclass of: SO_0000673
so part of: YIL002W-A
location: 350301..350510
location: region:350301-350510:1
so has part: feature:350301-350510:1:exon

NP_878098.1
type: Protein
SIO_000068: ncbiprotein

S000028835
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:350301-350510:1:exon

YIL002C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SJL1
gene: INP51
locus tag: YIL002C
gene synonym: SJL1
so part of: sequence
location: complement(<350591..>353431)
location: region:350591-353431:-1
so has part: feature:350591-353431:-1:exon
subclass of: SO_0000010

854815
type: Gene
SIO_000068: ncbigene

position:350591:-1
position: 350591
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:353431:-1
position: 353431
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:350591-353431:-1:exon

YIL002C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SJL1
gene: INP51
locus tag: YIL002C
gene synonym: SJL1
product: phosphoinositide 5-phosphatase INP51
transcript id: NM_001179352.3
SIO_010081: YIL002C
subclass of: SO_0000673
so part of: YIL002C
location: complement(<350591..>353431)
location: region:350591-353431:-1
so has part: feature:350591-353431:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:350591-353431:-1:exon

YIL002C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SJL1
gene: INP51
locus tag: YIL002C
gene synonym: SJL1
EC number: 3.1.3.36
experiment: EXISTENCE:direct assay:GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity [PMID:9565610|PMID:10224048]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:17452534]
experiment: EXISTENCE:direct assay:GO:0016020 membrane [PMID:9560389]
experiment: EXISTENCE:direct assay:GO:0046856 phosphatidylinositol dephosphorylation [PMID:10224048]
experiment: EXISTENCE:mutant phenotype:GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity [PMID:9438131|PMID:9565610]
experiment: EXISTENCE:mutant phenotype:GO:0046856 phosphatidylinositol dephosphorylation [PMID:9438131|PMID:9560389]
note: Phosphatidylinositol 4,5-bisphosphate 5-phosphatase; synaptojanin-like protein with an N-terminal Sac1 domain, plays a role in phosphatidylinositol 4,5-bisphosphate homeostasis and in endocytosis; null mutation confers cold-tolerant growth
codon start: 1
product: phosphoinositide 5-phosphatase INP51
translation: MRLFIGRRSRSIVISSNNYCLSFQRLRSIPGASSQQRQLSKTPSVTIKSYPDTDLSSDSNYLEVKSCIFNGLLGLVCLNGDIYVAVISGVQNVGFPRWKLIDHQVRPSESIYKVLDVDFYSLENDVFDYLLCERSEQNYDKLIHEHPCGPLKKLFSDGTFYYSRDFDISNIVKNHGLSHNLEYTVDNQDLSFIWNANLASEVINWRSKISNEEKQLFANAGFLTFVIRGYCKTALIEDGPNTASITIISRISTESKQDTLELEGISEDGRVSLFVETEIVVTTEKFIFSYTQVNGSIPLFWESVESQLLYGKKIKVTKDSIEAQGAFDRHFDNLTSKYGVVSIVNIIKPKSESQEKLALTYKDCAESKGIKITNIEYSSSVLTKSPHKLLYLLKQDIYEFGAFAYDISRGIYFAKQTGVLRISAFDSIEKPNTVERLVSKEVLELTTNEIDVFELTSPFLDAHDKLWSENYYWLDRTYTKHTKNSGKYTKVYSKLFGSRVRLYDPLHIYISQYLKQLRSKYTFEKDISIFAGTFNISGKIPKDDIKDWIFPKSMSKEDEMADLYVIGLEEVVELTPGHMLATDPYVRQFWEKKILTLLNGPGRKKKYIRLWSTQLGGILLLLFMNETEYSKVKHIEGDVKKTGFGGMASNKGAVAVSFKYSATRFCVLVSHLAAGLENVEQRHNDYKTIAKSIRFSKGLRIKDHDAIIWMGDFNYRILMSNEDVRRKIVSKEYASLFEKDQLNQQMIAGESFPYFHEMAIDFPPTYKFDPGTKNYDTSEKMRIPAWTDRILSRGEVLEQLEYKCCEDILFSDHRPVYAIFRARVTVVDEQKKTTLGTQIYEKIMERLEGLDDDEKIAVLSDDAFVIESFEGSDSIAGPTHSPTPIPEPKRGRKLPPPSSDLKKWWIGSGKQVKVVLDVDPAVYMINPKRDPNPFVENEDEPLFIER
SIO_010081: YIL002C
subclass of: SO_0000673
so part of: YIL002C
location: complement(350591..353431)
location: region:350591-353431:-1
so has part: feature:350591-353431:-1:exon

NP_012264.3
type: Protein
SIO_000068: ncbiprotein

S000001264
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:350591-353431:-1:exon

YIL001W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YIL001W
so part of: sequence
location: <353940..>355481
location: region:353940-355481:1
so has part: feature:353940-355481:1:exon
subclass of: SO_0000010

854816
type: Gene
SIO_000068: ncbigene

position:353940:1
position: 353940
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:355481:1
position: 355481
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:353940-355481:1:exon

YIL001W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YIL001W
product: uncharacterized protein
transcript id: NM_001179351.3
SIO_010081: YIL001W
subclass of: SO_0000673
so part of: YIL001W
location: <353940..>355481
location: region:353940-355481:1
so has part: feature:353940-355481:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:353940-355481:1:exon

YIL001W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YIL001W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
note: hypothetical protein; contains a BTB/POZ domain which generally function in protein interactions; deletion slightly improved competitive fitness in rich media; GFP-tagged protein is localized to the cytoplasm
codon start: 1
product: uncharacterized protein
translation: MADKLMDKNFEELCYSCRTGDMDNVDRLISTGVNVNSVDKFDNSPLFLASLCGHEAVVKLLLQRGAVCDRDRYEGARCIYGALTDTIRDTLLSYDISKAVDVKQPFATHISSMYNDEGFLKRDITFRVSNGKLFTAHKFLLCARSEILAEKMVNEWAKHEIVSLEVRPDIFDIFLKFLYLIPILHQIEPGQYEELIELSSKFDIELLPEFLDKARHTADPTEKSRLMSDYQYKFTEVARSQLLIFVNNCIFRSTVDLANSERRVFSLMNCPAYPDVQLMVKNRNGAIRIYPCHLAVLSRAEYFKVMFTNNFKEKVTYIKAKHVTGKYNSIIPQLTLPNCEFEVAEIILRYLYADNTDIPWMYAVDVLLLADILLEDRLKTIASTIITQSKEFIQQYNVFDVLYLSWEIGVERLEQFAAKFIAIHLQELYKDPEIKRAIMLSSQRISLRQETDTIELVDDIRYYLLRKYSFEPDDVELFENQDDLEYLKQVGYLEYRKDMGMLDNILADLELDV
SIO_010081: YIL001W
subclass of: SO_0000673
so part of: YIL001W
location: 353940..355481
location: region:353940-355481:1
so has part: feature:353940-355481:1:exon

NP_012265.3
type: Protein
SIO_000068: ncbiprotein

S000001263
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:353940-355481:1:exon

centromere
type: Centromere
subclass of: SO_0000577
RO_0002162: 559292
note: CEN9; Chromosome IX centromere
so part of: sequence
location: 355629..355745
location: region:355629-355745:1
so has part: feature:355629-355745:1:region

S000006470
type: SGD
SIO_000068: sgd

position:355629:1
position: 355629
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:355745:1
position: 355745
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:355629-355745:1:region

centromere
type: Centromere
subclass of: SO_0000577
RO_0002162: 559292
note: CEN9_CDEI of CEN9
so part of: sequence
location: 355629..355638
location: region:355629-355638:1
so has part: feature:355629-355638:1:region

position:355638:1
position: 355638
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:355629-355638:1:region

centromere
type: Centromere
subclass of: SO_0000577
RO_0002162: 559292
note: CEN9_CDEII of CEN9
so part of: sequence
location: 355639..355720
location: region:355639-355720:1
so has part: feature:355639-355720:1:region

position:355639:1
position: 355639
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:355720:1
position: 355720
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:355639-355720:1:region

centromere
type: Centromere
subclass of: SO_0000577
RO_0002162: 559292
note: CEN9_CDEIII of CEN9
so part of: sequence
location: 355721..355745
location: region:355721-355745:1
so has part: feature:355721-355745:1:region

position:355721:1
position: 355721
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:355721-355745:1:region

YIR001C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RBP1
alternative label: RBP29
gene: SGN1
locus tag: YIR001C
gene synonym: RBP1; RBP29
so part of: sequence
location: complement(<356143..>356895)
location: region:356143-356895:-1
so has part: feature:356143-356895:-1:exon
subclass of: SO_0000010

854817
type: Gene
SIO_000068: ncbigene

position:356143:-1
position: 356143
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:356895:-1
position: 356895
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:356143-356895:-1:exon

YIR001C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RBP1
alternative label: RBP29
gene: SGN1
locus tag: YIR001C
gene synonym: RBP1; RBP29
product: Sgn1p
transcript id: NM_001179523.1
SIO_010081: YIR001C
subclass of: SO_0000673
so part of: YIR001C
location: complement(<356143..>356895)
location: region:356143-356895:-1
so has part: feature:356143-356895:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:356143-356895:-1:exon

YIR001C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RBP1
alternative label: RBP29
gene: SGN1
locus tag: YIR001C
gene synonym: RBP1; RBP29
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:10764794]
experiment: EXISTENCE:direct assay:GO:0008143 poly(A) binding [PMID:10764794]
experiment: EXISTENCE:genetic interaction:GO:0016071 mRNA metabolic process [PMID:10764794]
experiment: EXISTENCE:physical interaction:GO:0016071 mRNA metabolic process [PMID:10764794]
note: Cytoplasmic RNA-binding protein; contains an RNA recognition motif (RRM); may have a role in mRNA translation, as suggested by genetic interactions with genes encoding proteins involved in translational initiation
codon start: 1
product: Sgn1p
translation: MSQEEKVDAKATLKTEISNNKKNDKQELELDELVGKLSIEGTPQVSQKLSKEEKHAHQLEADSRSIFVGNITPDVTPEQIEDHFKDCGQIKRITLLYDRNTGTPKGYGYIEFESPAYREKALQLNGGELKGKKIAVSRKRTNIPGFNRHYNSQNQYFQQWQWNYPLMAYPNPDTFPYYPPYPPNQSPNQNFGYNKNNYYRSPYNNKNRTFQKKHFNSAKDSTKNIRSTSQKPVVMPSDNVKSSTQEKDSK
SIO_010081: YIR001C
subclass of: SO_0000673
so part of: YIR001C
location: complement(356143..356895)
location: region:356143-356895:-1
so has part: feature:356143-356895:-1:exon

NP_012266.1
type: Protein
SIO_000068: ncbiprotein

S000001440
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:356143-356895:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS920; Autonomously Replicating Sequence
so part of: sequence
location: 357160..357396
location: region:357160-357396:1
so has part: feature:357160-357396:1:region

S000118399
type: SGD
SIO_000068: sgd

position:357160:1
position: 357160
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:357396:1
position: 357396
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:357160-357396:1:region

YIR002C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MPH1
locus tag: YIR002C
so part of: sequence
location: complement(<357415..>360396)
location: region:357415-360396:-1
so has part: feature:357415-360396:-1:exon
subclass of: SO_0000010

854818
type: Gene
SIO_000068: ncbigene

position:357415:-1
position: 357415
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:360396:-1
position: 360396
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:357415-360396:-1:exon

YIR002C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MPH1
locus tag: YIR002C
product: 3'-5' DNA helicase
transcript id: NM_001179524.1
SIO_010081: YIR002C
subclass of: SO_0000673
so part of: YIR002C
location: complement(<357415..>360396)
location: region:357415-360396:-1
so has part: feature:357415-360396:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:357415-360396:-1:exon

YIR002C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MPH1
locus tag: YIR002C
EC number: 3.6.4.12
experiment: EXISTENCE:direct assay:GO:0000781 chromosome, telomeric region [PMID:26966248]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:10880470|PMID:19995966]
experiment: EXISTENCE:direct assay:GO:0033677 DNA/RNA helicase activity [PMID:26966248]
experiment: EXISTENCE:direct assay:GO:0043138 3'-5' DNA helicase activity [PMID:15634678]
experiment: EXISTENCE:direct assay:GO:0060543 negative regulation of strand invasion [PMID:19136626]
experiment: EXISTENCE:direct assay:GO:0070336 flap-structured DNA binding [PMID:19181670]
experiment: EXISTENCE:genetic interaction:GO:0033567 DNA replication, Okazaki fragment processing [PMID:19181670]
experiment: EXISTENCE:genetic interaction:GO:0036297 interstrand cross-link repair [PMID:22912599]
experiment: EXISTENCE:mutant phenotype:GO:0000725 recombinational repair [PMID:19995966]
experiment: EXISTENCE:mutant phenotype:GO:0007535 donor selection [PMID:27257873]
experiment: EXISTENCE:mutant phenotype:GO:0060543 negative regulation of strand invasion [PMID:19136626]
experiment: EXISTENCE:physical interaction:GO:0007535 donor selection [PMID:27257873]
note: 3'-5' DNA helicase involved in error-free bypass of DNA lesions; binds flap DNA, stimulates activity of Rad27p and Dna2p; prevents crossovers between ectopic sequences by removing substrates for Mus81-Mms4 or Rad1-Rad10 cleavage; homolog of human FANCM Fanconi anemia protein that is involved in stabilizing and remodeling blocked replication forks; member of SF2 DExD/H superfamily of helicases; nonsense or missense mutations in FANCM can make people more likely to get cancer
codon start: 1
product: 3'-5' DNA helicase
translation: MASADDYFSDFEDDELDKLYEKAINKSVKETITRRAVPVQKDLHDNVLPGQKTVYEEIQRDVSFGPTHHELDYDALSFYVYPTNYEVRDYQYTIVHKSLFQNTLCAIPTGMGKTFIASTVMLNYFRWTKKAKIIFTAPTRPLVAQQIKACLGITGIPSDQTAILLDKSRKNREEIWANKRVFFATPQVVENDLKRGVLDPKDIVCLVIDEAHRATGSSAYTNVVKFIDRFNSSYRLLALTATPASDLEGVQEVVNNLDISKIEIRTEESMDIVKYMKKRKKEKIEVPLLLEIEDIIEQLGMAVKPVLQQAIELGIYEECDPSQINAFKAMQQSQKIIANPTIPEGIKWRNFFILQLLNNVGQMLKRLKIYGIRTFFNYFQNKCTEFTTKYNLKKSTNKIAAEFYYHPILKNIKNQCENYLSDPKFVGHGKLQCVRDELMDFFQKRGSDSRVIIFTELRESALEIVKFIDSVADDQIRPHIFIGQARAKEGFDEVKYTRKHAPKGRKKVERLHRQEQEKFLEAERTKRAANDKLERSARRTGSSEEAQISGMNQKMQKEVIHNFKKGEYNVLVCTSIGEEGLDIGEVDLIICYDTTSSPIKNIQRMGRTGRKRDGKIVLLFSSNESYKFERAMEDYSTLQALISKQCIDYKKSDRIIPEDIIPECHETLITINDENEIINEMEDVDEVIRYATQCMMGKKVKPKKAITKKKRVQENKKPKKFFMPDNVETSIVSASTLINKFLVNESGGKQLVTSNENPSKKRKIFKALDNLENDSTEEASSSLETEDEEVSDDNNVFIAEGQNGCQKDLETAIIRTGESLTTLKPLHNFERPNMALFVNDCGLPTKIEKNVKDIRGNQHNLEKEKSCTVDKNNMVLSLDDWNFFRNRYIPEGVSFDVEPNFVQYTKGVKVPHCHKVSKIITLFNDESNDNKKRTIDMNYTKCLARGMLRDEKKFVKVNDKSQVDNNSVNHDSSQSFTLSNAELDDILGSDSDF
SIO_010081: YIR002C
subclass of: SO_0000673
so part of: YIR002C
location: complement(357415..360396)
location: region:357415-360396:-1
so has part: feature:357415-360396:-1:exon

NP_012267.1
type: Protein
SIO_000068: ncbiprotein

S000001441
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:357415-360396:-1:exon

YIR003W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: AIM21
locus tag: YIR003W
so part of: sequence
location: <360885..>362924
location: region:360885-362924:1
so has part: feature:360885-362924:1:exon
subclass of: SO_0000010

854819
type: Gene
SIO_000068: ncbigene

position:360885:1
position: 360885
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:362924:1
position: 362924
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:360885-362924:1:exon

YIR003W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: AIM21
locus tag: YIR003W
product: Aim21p
transcript id: NM_001179525.3
SIO_010081: YIR003W
subclass of: SO_0000673
so part of: YIR003W
location: <360885..>362924
location: region:360885-362924:1
so has part: feature:360885-362924:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:360885-362924:1:exon

YIR003W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: AIM21
locus tag: YIR003W
experiment: EXISTENCE:direct assay:GO:0015629 actin cytoskeleton [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0030479 actin cortical patch [PMID:28706108|PMID:29467252]
experiment: EXISTENCE:direct assay:GO:0030837 negative regulation of actin filament polymerization [PMID:29467252]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:19053807]
experiment: EXISTENCE:direct assay:GO:0051015 actin filament binding [PMID:29467252]
experiment: EXISTENCE:mutant phenotype:GO:0034642 mitochondrion migration along actin filament [PMID:19300474]
experiment: EXISTENCE:physical interaction:GO:0110131 Aim21-Tda2 complex [PMID:28706108|PMID:29467252]
note: Subunit of a complex that associates with actin filaments; forms a complex with Tda2p that inhibits barbed end F-actin assembly; elevates actin monomer pools to increase endocytotic efficiency and to regulate the distribution of actin between cables and patches; Aim21p/Tda2p forms a larger complex with actin capping proteins Cap1p and Cap2p; involved in mitochondrial migration along actin filaments; recruited to cortical actin patches by SH3 domain-containing proteins Bbc1p and Abp1p
codon start: 1
product: Aim21p
translation: MPSEVTPKVPERPSRRKTSELFPLSGSESGDIKANSEPPTPAGTPNVPTRRPILKAKTMTSFESGMDQESLPKVPLQRPVRRSTTEELNNVMNNTSKELEEIESLISKHNIHNVSRKKSPTSVEEGKVAAIHQNGQRSASDNKTSTNPSPLEKNEHEGAEGNESAISPSNLVNKSNNEVTEHSDSEDLTEKQKVHAALDNEAGDRSHFEEKLIPGDMKVQVDVSKDVEEGSLNALPPSGITESDDKAEKFTKHPESSLEELQKHQEQQEEKIFQNPTDEESTTSLNEKQEGKDNMEVNSQPQGPSDTETVIAATSSNVPSQIASEEENDVPVIPRSRPKKDFEAHVQKEELPNTQEKRVSEECDSTLISTEEESKIPKIPSERPKRRAPPPVPKKPSSRIAAFQEMLQKQQQQDLHNNGNSSATTASADIAKKHTDSSITSDTTKADFTSKLNGLFALPGMVNPGQLPPSLEKKLSSPDTESKLGPQDQSQAKTGPLGGTRRGRGPRGRKLPSKVASVEKIEEDDNTNKIEIFNNWNVSSSFSKEKVLIDTTPGEQAERALDEKSKSIPEEQREQSPNKMEAALCPFELDEKEKLPANAESDPLSQLPQTNAVGNRKAISEESLSPSEAIANRDQNDTTEIQEQQMEDQMEVDMERELSGGYEDVDSALHSEEASFHSL
SIO_010081: YIR003W
subclass of: SO_0000673
so part of: YIR003W
location: 360885..362924
location: region:360885-362924:1
so has part: feature:360885-362924:1:exon

NP_012268.3
type: Protein
SIO_000068: ncbiprotein

S000001442
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:360885-362924:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS921; Putative replication origin; identified in multiple array studies, not yet confirmed by plasmid-based assay
so part of: sequence
location: 362924..363221
location: region:362924-363221:1
so has part: feature:362924-363221:1:region

S000130161
type: SGD
SIO_000068: sgd

position:363221:1
position: 363221
reference: sequence
type: ForwardStrandPosition
type: ExactPosition
type: FuzzyPosition

urn:…
SIO_000300: 1
SIO_000628: feature:362924-363221:1:region

YIR004W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ICS1
alternative label: PAS22
gene: DJP1
locus tag: YIR004W
gene synonym: ICS1; PAS22
so part of: sequence
location: <363221..>364519
location: region:363221-364519:1
so has part: feature:363221-364519:1:exon
subclass of: SO_0000010

854820
type: Gene
SIO_000068: ncbigene

position:364519:1
position: 364519
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:363221-364519:1:exon

YIR004W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ICS1
alternative label: PAS22
gene: DJP1
locus tag: YIR004W
gene synonym: ICS1; PAS22
product: Djp1p
transcript id: NM_001179526.1
SIO_010081: YIR004W
subclass of: SO_0000673
so part of: YIR004W
location: <363221..>364519
location: region:363221-364519:1
so has part: feature:363221-364519:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:363221-364519:1:exon

YIR004W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ICS1
alternative label: PAS22
gene: DJP1
locus tag: YIR004W
gene synonym: ICS1; PAS22
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:9679141]
experiment: EXISTENCE:direct assay:GO:0005933 cellular bud [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0006626 protein targeting to mitochondrion [PMID:30213914]
experiment: EXISTENCE:mutant phenotype:GO:0016558 protein import into peroxisome matrix [PMID:9679141]
experiment: EXISTENCE:mutant phenotype:GO:0045040 protein insertion into mitochondrial outer membrane [PMID:23959800]
note: ER-associated chaperone involved in protein targeting; redirects mitochondrial membrane protein precursors to mitochondrial translocation system; required for peroxisomal protein import and involved in peroxisome assembly; facilitates import of Mim1p and Mim2p into the mitochondrial outer membrane; homologous to E. coli DnaJ
codon start: 1
product: Djp1p
translation: MVVDTEYYDLLGVSTTASSIEIKKAYRKKSIQEHPDKNPNDPTATERFQAISEAYQVLGDDDLRAKYDKYGRKEAIPQGGFEDAAEQFSVIFGGDAFASYIGELMLLKNLQKTEELNAEDEAEKEKENVETMEESPADGKTNGTTNAVDAALGNTNEKDDKNKARTTSGNLTVHDGNKKNEQVGAEAKKKKTKLEQFEEEQEVEKQKRVDQLSKTLIERLSILTESVYDDACKDSFKKKFEEEANLLKMESFGLDILHTIGDVYYEKAEIFLASQNLFGMGGIFHSMKAKGGVFMDTLRTVSAAIDAQNTMKELEKMKEASTNNEPLFDKDGNEQIKPTTEELAQQEQLLMGKVLSAAWHGSKYEITSTLRGVCKKVLEDDSVSKKTLIRRAEAMKLLGEVFKKTFRTKVEQEEAQIFEELVAEATKKKRHT
SIO_010081: YIR004W
subclass of: SO_0000673
so part of: YIR004W
location: 363221..364519
location: region:363221-364519:1
so has part: feature:363221-364519:1:exon

NP_012269.1
type: Protein
SIO_000068: ncbiprotein

S000001443
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:363221-364519:1:exon

YIR005W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SNU17
gene: IST3
locus tag: YIR005W
gene synonym: SNU17
so part of: sequence
location: <364889..>365335
location: region:364889-365335:1
so has part: feature:364889-365335:1:exon
subclass of: SO_0000010

854821
type: Gene
SIO_000068: ncbigene

position:364889:1
position: 364889
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:365335:1
position: 365335
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:364889-365335:1:exon

YIR005W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SNU17
gene: IST3
locus tag: YIR005W
gene synonym: SNU17
product: U2 snRNP complex subunit IST3
transcript id: NM_001179527.1
SIO_010081: YIR005W
subclass of: SO_0000673
so part of: YIR005W
location: <364889..>365335
location: region:364889-365335:1
so has part: feature:364889-365335:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:364889-365335:1:exon

YIR005W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SNU17
gene: IST3
locus tag: YIR005W
gene synonym: SNU17
experiment: EXISTENCE:direct assay:GO:0000384 first spliceosomal transesterification activity [PMID:11287609]
experiment: EXISTENCE:direct assay:GO:0000398 mRNA splicing, via spliceosome [PMID:15565172]
experiment: EXISTENCE:direct assay:GO:0005686 U2 snRNP [PMID:16314500]
experiment: EXISTENCE:direct assay:GO:0070274 RES complex [PMID:15565172]
experiment: EXISTENCE:mutant phenotype:GO:0000245 spliceosomal complex assembly [PMID:11287609]
experiment: EXISTENCE:mutant phenotype:GO:0000349 generation of catalytic spliceosome for first transesterification step [PMID:11287609]
experiment: EXISTENCE:mutant phenotype:GO:0000384 first spliceosomal transesterification activity [PMID:11287609]
experiment: EXISTENCE:mutant phenotype:GO:0006406 mRNA export from nucleus [PMID:15565172]
note: Component of the U2 snRNP; required for the first catalytic step of splicing and for spliceosomal assembly; interacts with Rds3p and is required for Mer1p-activated splicing; diploid mutants have a specific defect in MATa1 pre-mRNA splicing which leads to haploid gene expression in diploids
codon start: 1
product: U2 snRNP complex subunit IST3
translation: MNKIQQINDKELQSGILSPHQSWHNEYKDNAYIYIGNLNRELTEGDILTVFSEYGVPVDVILSRDENTGESQGFAYLKYEDQRSTILAVDNLNGFKIGGRALKIDHTFYRPKRSLQKYYEAVKEELDRDIVSKNNAEKLILAKKDQPN
SIO_010081: YIR005W
subclass of: SO_0000673
so part of: YIR005W
location: 364889..365335
location: region:364889-365335:1
so has part: feature:364889-365335:1:exon

NP_012270.1
type: Protein
SIO_000068: ncbiprotein

S000001444
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:364889-365335:1:exon

YIR006C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: DIM2
alternative label: MDP3
alternative label: MIP3
gene: PAN1
locus tag: YIR006C
gene synonym: DIM2; MDP3; MIP3
so part of: sequence
location: complement(<365466..>369908)
location: region:365466-369908:-1
so has part: feature:365466-369908:-1:exon
subclass of: SO_0000010

854822
type: Gene
SIO_000068: ncbigene

position:365466:-1
position: 365466
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:369908:-1
position: 369908
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:365466-369908:-1:exon

YIR006C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: DIM2
alternative label: MDP3
alternative label: MIP3
gene: PAN1
locus tag: YIR006C
gene synonym: DIM2; MDP3; MIP3
product: Pan1p
transcript id: NM_001179528.3
SIO_010081: YIR006C
subclass of: SO_0000673
so part of: YIR006C
location: complement(<365466..>369908)
location: region:365466-369908:-1
so has part: feature:365466-369908:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:365466-369908:-1:exon

YIR006C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: DIM2
alternative label: MDP3
alternative label: MIP3
gene: PAN1
locus tag: YIR006C
gene synonym: DIM2; MDP3; MIP3
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:17967424]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:17967424]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0030479 actin cortical patch [PMID:14622601|PMID:16824951]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:19053807]
experiment: EXISTENCE:direct assay:GO:0071933 Arp2/3 complex binding [PMID:11433303]
experiment: EXISTENCE:direct assay:GO:1990964 actin cytoskeleton-regulatory complex [PMID:10594004|PMID:17151356]
experiment: EXISTENCE:direct assay:GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation [PMID:16824951|PMID:11433303|PMID:17151356]
experiment: EXISTENCE:genetic interaction:GO:0061709 reticulophagy [PMID:35101986]
experiment: EXISTENCE:mutant phenotype:GO:0000147 actin cortical patch assembly [PMID:18177206]
experiment: EXISTENCE:mutant phenotype:GO:0006897 endocytosis [PMID:8978817]
experiment: EXISTENCE:mutant phenotype:GO:0007120 axial cellular bud site selection [PMID:8756649]
experiment: EXISTENCE:mutant phenotype:GO:0007121 bipolar cellular bud site selection [PMID:8756649]
experiment: EXISTENCE:physical interaction:GO:1990964 actin cytoskeleton-regulatory complex [PMID:17151356]
note: Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p; associates with actin patches on cell cortex; promotes protein-protein interactions essential for endocytosis; regulates late stages of endocytosis; binds to and activates Arp2/3 complex in vitro; phosphorylation of Thr-1225 is regulated by MAPK Hog1p in response to osmotic stress
codon start: 1
product: Pan1p
translation: MYNPYQQQGMGYQQQQQQQQQQPNGFYPQQQQGQSSNQPQGQPQPQQQMAFNQPQATGIGGMPQSFGNSFSSMPQQPQTGYNNNGNNGSVYGNGNFGQQPQQQQQQAKPQHTGYVPNSSMPMMNTTGTMPPPNPAQQPQLQSIQPQGTGYYQAANTANVHSVQPLQSQGTGYYVSTPNLISSNQTQQPLQAQGTGYYQSQPQQVPPPQQAQSLQPLKPQQTGFYLQPQNQAPLEPLKPTATGFVNSFANNGLNNDIKIPAIRLSFITAQDQAKFETLFRSIVTNGSNTVSGANCRKILMRSGLPPSQLARIWTLCDTSKAGELLFPEFALAMHLINDVLQGDTIPYELDSKTKNEVSSFIDAINLSIANQDSSANDAPKTPFDEFITAGVQNLQPQPTGYMPQTSFGIPLQSQITGGGVASALNPQSTGFMAPTTFNMSMNTGTPGLNPQITGGAPASMQPNITGNALQPQTTGMMPQTTGMMPQTTGMMPQTSFGVNLGPQLTGGALQSQYTGGYGSVMPQQSGPASMPNLSFNQQGLQSQLTGLQPQPTGFLPPSNFSATMPLTAQKTGFGNNEIYTKSNFNNNLIDNSSQDKISTEEKSLFYKIFETFDTQNKGLLDSPTAVEIFRKSGLNRADLEQIWNLCDINNTGQLNKQEFALGMHLVYGKLNGKPIPNVLPSSLIPSSTKLLDNLKNQLKTEPTTTKEKPSFGKIDALSYKNNDDDVLPNYRNRRKVYSAKNEEQSSFSSPSAKSVNHSSSTLQTDDISVDKTVEKKTAKPKYAGFSREINLKNIASLENEIKNISNPENCYDSSIPSDLTSRFDAIIAKLPNLFNEISTIDNEITNAKIQLYRKKNPSSIIGSGPNGEITENDRKKAKSRALLRARMSALTGKSTESEDSLSMEDEQQSAEIKRIQQENGKNQEIIKDIRSSISDISASLKSTMTGSNMISNQEFERWEFGIGLEDGVREFLDDLKSNSNKSVTESSPFVPSSTPTPVDDRSSSPSYSQFKTAEERAAYLKEQAKKRMKEKLAKFDKNRRNVTQSSRSISSENSREQPQQIAGSSNLVEPRATPFQEEKYVEVAQPTQPVQSTQPVQPTQPVQPTQPVQPTQPVQPTQPVQPTQPVQNVYNAKQESDDEDEDDEEKRLQEELKRLKLKKKADKEKRLAALRKQIEDAQNESDEEETNGKDNFGGHVNVPQAAPVAPSAAFSQNSTNAPRSVHAAVTPAAGKNSTGLPSTTMGHNPYFKDASASSTSTFDARAAEMQRRIQRGLDEDEDDGWSDEDESNNRVAVDNKVEEAKIGHPDHARAPPVTAAPLPSVTPVPPAVPVPQANTSNEKSSPIPIAPIPPSVTQEPPVPLAPPLPAVDGFQEPPIPSAPAIATAVQKSGSSTPALAGGVLPPPPPLPTQQASTSEPIIAHVDNYNGAEKGTGAYGSDSDDDVLSIPESVGTDEEEEGAQPVSTAGIPSIPPAGIPPPPPLP
SIO_010081: YIR006C
subclass of: SO_0000673
so part of: YIR006C
location: complement(365466..369908)
location: region:365466-369908:-1
so has part: feature:365466-369908:-1:exon

NP_012271.3
type: Protein
SIO_000068: ncbiprotein

S000001445
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:365466-369908:-1:exon

YNCI0011W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCI0011W
so part of: sequence
location: 370417..370488
location: region:370417-370488:1
so has part: feature:370417-370488:1:exon
subclass of: SO_0000663

854823
type: Gene
SIO_000068: ncbigene

position:370417:1
position: 370417
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:370488:1
position: 370488
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:370417-370488:1:exon

YNCI0011W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCI0011W
product: tRNA-Glu
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Glutamate tRNA (tRNA-Glu), predicted by tRNAscan-SE analysis; thiolation of uridine at wobble position (34) requires Ncs6p
SIO_010081: YNCI0011W
subclass of: SO_0000673
so part of: YNCI0011W
location: 370417..370488
location: region:370417-370488:1
so has part: feature:370417-370488:1:exon

S000006556
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:370417-370488:1:exon

YIR007W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: EGH1
locus tag: YIR007W
so part of: sequence
location: <370704..>372998
location: region:370704-372998:1
so has part: feature:370704-372998:1:exon
subclass of: SO_0000010

854824
type: Gene
SIO_000068: ncbigene

position:370704:1
position: 370704
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:372998:1
position: 372998
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:370704-372998:1:exon

YIR007W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: EGH1
locus tag: YIR007W
product: hydrolase
transcript id: NM_001179529.3
SIO_010081: YIR007W
subclass of: SO_0000673
so part of: YIR007W
location: <370704..>372998
location: region:370704-372998:1
so has part: feature:370704-372998:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:370704-372998:1:exon

YIR007W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: EGH1
locus tag: YIR007W
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26116408]
experiment: EXISTENCE:direct assay:GO:0050295 steryl-beta-glucosidase activity [PMID:26116408]
experiment: EXISTENCE:mutant phenotype:GO:1904462 ergosteryl 3-beta-D-glucoside catabolic process [PMID:26116408]
note: Steryl-beta-glucosidase with broad specificity for aglycones; has a role in ergosteryl-beta-glucoside catabolism; required for normal vacuolar morphology; has similarity to the C. neoformans ergosteryl-beta-glucosidase EGCrP2; localizes to the cytosol
codon start: 1
product: hydrolase
translation: MPAKIHISADGQFCDKDGNEIQLRGVNLDPSVKIPAKPFLSTHAPIENDTFFEDADKVSFINHPLVLDDIEQHIIRLKSLGYNTIRLPFTWESLEHAGPGQYDFDYMDYIVEVLTRINSVQQGMYIYLDPHQDVWSRFSGGSGAPLWTLYCAGFQPANFLATDAAILHNYYIDPKTGREVGKDEESYPKMVWPTNYFKLACQTMFTLFFGGKQYAPKCTINGENIQDYLQGRFNDAIMTLCARIKEKAPELFESNCIIGLESMNEPNCGYIGETNLDVIPKERNLKLGKTPTAFQSFMLGEGIECTIDQYKRTFFGFSKGKPCTINPKGKKAWLSAEERDAIDAKYNWERNPEWKPDTCIWKLHGVWEIQNGKRPVLLKPNYFSQPDATVFINNHFVDYYTGIYNKFREFDQELFIIIQPPVMKPPPNLQNSKILDNRTICACHFYDGMTLMYKTWNKRIGIDTYGLVNKKYSNPAFAVVLGENNIRKCIRKQLSEMQKDAKSMLGKKVPVFFTEIGIPFDMDDKKAYITNDYSSQTAALDALGFALEGSNLSYTLWCYCSINSHIWGDNWNNEDFSIWSPDDKPLYHDTRAKTPTPEPSPASTVASVSTSTSKSGSSQPPSFIKPDNHLDLDSPSCTLKSDLSGFRALDAIMRPFPIQIHGRFEFAEFNLCNKSYLLKLVGKTTPEQITVPTYIFIPRHHFTPSRLSIRSSSGHYTYNTDYQVLEWFHEPGHQFIEICAKSKSRPNTPGSDTSNDLPAECVIS
SIO_010081: YIR007W
subclass of: SO_0000673
so part of: YIR007W
location: 370704..372998
location: region:370704-372998:1
so has part: feature:370704-372998:1:exon

NP_012272.3
type: Protein
SIO_000068: ncbiprotein

S000001446
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:370704-372998:1:exon

YIR008C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PRI1
locus tag: YIR008C
so part of: sequence
location: complement(<373077..>374306)
location: region:373077-374306:-1
so has part: feature:373077-374306:-1:exon
subclass of: SO_0000010

854825
type: Gene
SIO_000068: ncbigene

position:373077:-1
position: 373077
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:374306:-1
position: 374306
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:373077-374306:-1:exon

YIR008C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PRI1
locus tag: YIR008C
product: DNA primase subunit PRI1
transcript id: NM_001179530.1
SIO_010081: YIR008C
subclass of: SO_0000673
so part of: YIR008C
location: complement(<373077..>374306)
location: region:373077-374306:-1
so has part: feature:373077-374306:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:373077-374306:-1:exon

YIR008C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PRI1
locus tag: YIR008C
experiment: EXISTENCE:curator inference:GO:0006270 DNA replication initiation [PMID:3888995]
experiment: EXISTENCE:curator inference:GO:0006273 lagging strand elongation [PMID:3888995]
experiment: EXISTENCE:direct assay:GO:0003697 single-stranded DNA binding [PMID:20404922]
experiment: EXISTENCE:direct assay:GO:0003896 DNA primase activity [PMID:3888995|PMID:2644256|PMID:3061469]
experiment: EXISTENCE:direct assay:GO:0005658 alpha DNA polymerase:primase complex [PMID:3888995|PMID:22593576]
experiment: EXISTENCE:direct assay:GO:0006269 DNA replication, synthesis of RNA primer [PMID:2644256]
experiment: EXISTENCE:direct assay:GO:0043596 nuclear replication fork [PMID:16103218]
experiment: EXISTENCE:genetic interaction:GO:0003896 DNA primase activity [PMID:8436268]
experiment: EXISTENCE:mutant phenotype:GO:0003896 DNA primase activity [PMID:8436268]
experiment: EXISTENCE:mutant phenotype:GO:0006260 DNA replication [PMID:2023935]
note: Subunit of DNA primase; DNA primase is required for DNA synthesis and double-strand break repair
codon start: 1
product: DNA primase subunit PRI1
translation: MTNSVKTNGPSSSDMEYYYKSLYPFKHIFNWLNHSPKPSRDMINREFAMAFRSGAYKRYNSFNSVQDFKAQIEKANPDRFEIGAIYNKPPRERDTLLKSELKALEKELVFDIDMDDYDAFRTCCSGAQVCSKCWKFISLAMKITNTALREDFGYKDFIWVFSGRRGAHCWVSDKRARALTDVQRRNVLDYVNVIRDRNTDKRLALKRPYHPHLARSLEQLKPFFVSIMLEEQNPWEDDQHAIQTLLPALYDKQLIDSLKKYWLDNPRRSSKEKWNDIDQIATSLFKGPKQDSHIIKLRECKEDLVLMTLYPKLDVEVTKQTIHLLKAPFCIHPATGNVCVPIDESFAPEKAPKLIDLQTEMEKNNDVSLTALQPFINQFQAYVSSLLKNELGSVKREREDDDEPASLDF
SIO_010081: YIR008C
subclass of: SO_0000673
so part of: YIR008C
location: complement(373077..374306)
location: region:373077-374306:-1
so has part: feature:373077-374306:-1:exon

NP_012273.1
type: Protein
SIO_000068: ncbiprotein

S000001447
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:373077-374306:-1:exon

YIR009W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YIB9
gene: MSL1
locus tag: YIR009W
gene synonym: YIB9
so part of: sequence
location: <374525..>374860
location: region:374525-374860:1
so has part: feature:374525-374860:1:exon
subclass of: SO_0000010

854826
type: Gene
SIO_000068: ncbigene

position:374525:1
position: 374525
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:374860:1
position: 374860
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:374525-374860:1:exon

YIR009W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YIB9
gene: MSL1
locus tag: YIR009W
gene synonym: YIB9
product: U2 snRNP complex subunit MSL1
transcript id: NM_001179531.1
SIO_010081: YIR009W
subclass of: SO_0000673
so part of: YIR009W
location: <374525..>374860
location: region:374525-374860:1
so has part: feature:374525-374860:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:374525-374860:1:exon

YIR009W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YIB9
gene: MSL1
locus tag: YIR009W
gene synonym: YIB9
experiment: EXISTENCE:direct assay:GO:0071004 U2-type prespliceosome [PMID:16618970]
experiment: EXISTENCE:mutant phenotype:GO:0000398 mRNA splicing, via spliceosome [PMID:9799242]
experiment: EXISTENCE:physical interaction:GO:0030620 U2 snRNA binding [PMID:8649387]
note: U2B component of U2 snRNP; involved in splicing, binds the U2 snRNA stem-loop IV in vitro but requires association of Lea1p for in vivo binding; does not contain the conserved C-terminal RNA binding domain found in other family members
codon start: 1
product: U2 snRNP complex subunit MSL1
translation: MVEPARKKQRIDRDTHHTVAEPVTEAKNTLYVSQLNEKINMQRLRVNLFLLFATFGEVLKVSMNFKKQRGQAFITMRTIDQASLAQISLNGERFFGKPLKVEFSKSETKTL
SIO_010081: YIR009W
subclass of: SO_0000673
so part of: YIR009W
location: 374525..374860
location: region:374525-374860:1
so has part: feature:374525-374860:1:exon

NP_012274.1
type: Protein
SIO_000068: ncbiprotein

S000001448
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:374525-374860:1:exon

YIR010W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: DSN1
locus tag: YIR010W
so part of: sequence
location: <375431..>377161
location: region:375431-377161:1
so has part: feature:375431-377161:1:exon
subclass of: SO_0000010

854827
type: Gene
SIO_000068: ncbigene

position:375431:1
position: 375431
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:377161:1
position: 377161
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:375431-377161:1:exon

YIR010W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: DSN1
locus tag: YIR010W
product: MIND complex subunit DSN1
transcript id: NM_001179532.3
SIO_010081: YIR010W
subclass of: SO_0000673
so part of: YIR010W
location: <375431..>377161
location: region:375431-377161:1
so has part: feature:375431-377161:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:375431-377161:1:exon

YIR010W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: DSN1
locus tag: YIR010W
experiment: EXISTENCE:direct assay:GO:0000444 MIS12/MIND type complex [PMID:14633972]
experiment: EXISTENCE:direct assay:GO:0000776 kinetochore [PMID:14657030|PMID:24402315]
experiment: EXISTENCE:direct assay:GO:0000922 spindle pole [PMID:12455957]
experiment: EXISTENCE:direct assay:GO:0007059 chromosome segregation [PMID:12455957]
experiment: EXISTENCE:genetic interaction:GO:0051455 monopolar spindle attachment to meiosis I kinetochore [PMID:23861669]
note: Essential component of the outer kinetochore MIND complex; joins kinetochore subunits contacting DNA to those contacting microtubules; phosphorylation promotes interaction between outer and inner kinetochore proteins; kinetochore receptor for monopolin, via interaction with Csm1p; essential for both meiotic and mitotic chromosome segregation; MIND complex consists of Mtw1p, Nnf1p, Nsl1p and Dsn1p; phosphorylated by monopolin subunit, Hrr25p and Aurora kinase, Ipl1p; modified by sumoylation
codon start: 1
product: MIND complex subunit DSN1
translation: MSLEPTQTVSGTPPMLHQRTHKQVYPLRMETIPILESDSKATLQSNEPTQKDEEETEYFENKQSVSNLSPDLKFKRHKNKHIQGFPTLGERLDNLQDIKKAKRVENFNSSAPIADDNHSGDATANATANATANATANVNASAMPAPYMPYYYYYHPMNAPTPAMIPYPGSPMHSIMPNSSLQPFYSQPTAAGGPDMTTPQNISSSQQLLPAPQLFPYGSFHQQQLQQPHYIQRTRERKKSIGSQRGRRLSMLASQANGGSTIISPHKDIPEEDFYTVVGNASFGKNLQIRQLFNWCLMRSLHKLELKAKNQEEEGELEHLTKKSKLESTKAETDYVDPKRLAMVIIKEFVDDLKKDHIAIDWEDEEKYEDEDEEKILDNTENYDDTELRQLFQENDDDDDDDDEVDYSEIQRSRRKFSERRKALPKEPKKLLPNSKNVENTKNLSILTSKVNAIKNEVKEWAVTLDTSRPDLEWQELTSFSSQPLEPLSDTEEPDLAIADVETKLETKVDELRYQSHILNSHSLALNEITNSKVNKLNIETMRKISSETDDDHSQVINPQQLLKGLSLSFSKKLDL
SIO_010081: YIR010W
subclass of: SO_0000673
so part of: YIR010W
location: 375431..377161
location: region:375431-377161:1
so has part: feature:375431-377161:1:exon

NP_012275.3
type: Protein
SIO_000068: ncbiprotein

S000001449
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:375431-377161:1:exon

YIR011C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: DBF8
alternative label: SSM5
gene: STS1
locus tag: YIR011C
gene synonym: DBF8; SSM5
so part of: sequence
location: complement(<377287..>378246)
location: region:377287-378246:-1
so has part: feature:377287-378246:-1:exon
subclass of: SO_0000010

854828
type: Gene
SIO_000068: ncbigene

position:377287:-1
position: 377287
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:378246:-1
position: 378246
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:377287-378246:-1:exon

YIR011C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: DBF8
alternative label: SSM5
gene: STS1
locus tag: YIR011C
gene synonym: DBF8; SSM5
product: Sts1p
transcript id: NM_001179533.1
SIO_010081: YIR011C
subclass of: SO_0000673
so part of: YIR011C
location: complement(<377287..>378246)
location: region:377287-378246:-1
so has part: feature:377287-378246:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:377287-378246:-1:exon

YIR011C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: DBF8
alternative label: SSM5
gene: STS1
locus tag: YIR011C
gene synonym: DBF8; SSM5
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:10913188]
experiment: EXISTENCE:direct assay:GO:0070628 proteasome binding [PMID:17916559]
experiment: EXISTENCE:mutant phenotype:GO:0007059 chromosome segregation [PMID:8065366]
experiment: EXISTENCE:mutant phenotype:GO:0031144 proteasome localization [PMID:21075847]
experiment: EXISTENCE:mutant phenotype:GO:0071630 nuclear protein quality control by the ubiquitin-proteasome system [PMID:21075847]
note: Protein required for localizing proteasomes to the nucleus; involved in cotranslational protein degradation; mediates interaction between nuclear import factor Srp1p and the proteasome; Sts1p and Srp1p couple proteasomes to nascent polypeptides emerging from the ribosome for cotranslational degradation; involved in ubiquitin-mediated protein degradation
codon start: 1
product: Sts1p
translation: MMGFEWGFKPSSKITQSTVSSQGTGNVMIPTAGVKQKRRYANEEQEEEELPRNKNVMKYGGVSKRRPQPGSLIRGQPLPLQRGMELMNKNQLQQLLVDLMTKHPEIQQSVHTRVIGLDFSIQKCLDMLKQKSEAVYQSIPYNRSYESNKLDDYAFVRMKPQILEFLNCLVDFILDNIPPRLENLHASLKFLDICTELVIKLPRFELASNNYYYDKCIEQLSHVWCTLIEHVARDRIILLADNSSVWKSHMTRLQVYNEHSNGLLERPLQLFKSLDMGSPSAASSSTLSLQESIIYHHDTMTANENNNNSGSAATDSPFN
SIO_010081: YIR011C
subclass of: SO_0000673
so part of: YIR011C
location: complement(377287..378246)
location: region:377287-378246:-1
so has part: feature:377287-378246:-1:exon

NP_012276.1
type: Protein
SIO_000068: ncbiprotein

S000001450
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:377287-378246:-1:exon

YIR012W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SQT1
locus tag: YIR012W
so part of: sequence
location: <378486..>379781
location: region:378486-379781:1
so has part: feature:378486-379781:1:exon
subclass of: SO_0000010

854829
type: Gene
SIO_000068: ncbigene

position:378486:1
position: 378486
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:379781:1
position: 379781
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:378486-379781:1:exon

YIR012W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SQT1
locus tag: YIR012W
product: Sqt1p
transcript id: NM_001179534.1
SIO_010081: YIR012W
subclass of: SO_0000673
so part of: YIR012W
location: <378486..>379781
location: region:378486-379781:1
so has part: feature:378486-379781:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:378486-379781:1:exon

YIR012W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SQT1
locus tag: YIR012W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:9271392]
experiment: EXISTENCE:direct assay:GO:0051082 unfolded protein binding [PMID:26112308]
experiment: EXISTENCE:mutant phenotype:GO:0000027 ribosomal large subunit assembly [PMID:9271392]
experiment: EXISTENCE:mutant phenotype:GO:0042273 ribosomal large subunit biogenesis [PMID:26112308]
note: Specific assembly chaperone for ribosomal protein Rpl10p; co-translationally associates with nascent Rpl10p, preventing aggregation; involved in biogenesis of the ribosomal large subunit; contains multiple WD repeats; interacts genetically and physically with Qsr1p; protein abundance increases in response to DNA replication stress
codon start: 1
product: Sqt1p
translation: MEPQEEFITTEEVEQEIVPTVEVEQDVPVDIEGENDDDDEMMNDDEEALEVDMSNNSLTYFDKHTDSVFAIGHHPNLPLVCTGGGDNLAHLWTSHSQPPKFAGTLTGYGESVISCSFTSEGGFLVTADMSGKVLVHMGQKGGAQWKLASQMQEVEEIVWLKTHPTIARTFAFGATDGSVWCYQINEQDGSLEQLMSGFVHQQDCSMGEFINTDKGENTLELVTCSLDSTIVAWNCFTGQQLFKITQAEIKGLEAPWISLSLAPETLTKGNSGVVACGSNNGLLAVINCNNGGAILHLSTVIELKPEQDELDASIESISWSSKFSLMAIGLVCGEILLYDTSAWRVRHKFVLEDSVTKLMFDNDDLFASCINGKVYQFNARTGQEKFVCVGHNMGVLDFILLHPVANTGTEQKRKVITAGDEGVSLVFEVPN
SIO_010081: YIR012W
subclass of: SO_0000673
so part of: YIR012W
location: 378486..379781
location: region:378486-379781:1
so has part: feature:378486-379781:1:exon

NP_012277.1
type: Protein
SIO_000068: ncbiprotein

S000001451
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:378486-379781:1:exon

YIR013C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GAT4
locus tag: YIR013C
so part of: sequence
location: complement(<380019..>380384)
location: region:380019-380384:-1
so has part: feature:380019-380384:-1:exon
subclass of: SO_0000010

854830
type: Gene
SIO_000068: ncbigene

position:380019:-1
position: 380019
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:380384:-1
position: 380384
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:380019-380384:-1:exon

YIR013C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GAT4
locus tag: YIR013C
product: Gat4p
transcript id: NM_001179535.3
SIO_010081: YIR013C
subclass of: SO_0000673
so part of: YIR013C
location: complement(<380019..>380384)
location: region:380019-380384:-1
so has part: feature:380019-380384:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:380019-380384:-1:exon

YIR013C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GAT4
locus tag: YIR013C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:24390141]
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:19158363]
experiment: EXISTENCE:direct assay:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:10392447]
note: Protein containing GATA family zinc finger motifs; involved in spore wall assembly; sequence similarity to GAT3, and the double mutant gat3 gat4 exhibits reduced dityrosine fluorescence relative to the single mutants
codon start: 1
product: Gat4p
translation: MSTKLPIVISNGTAFKKVPVQLLLNSGSEAQHGLPRNADSQPARPRTGITRTCGQCGEIKTSLQWREGPNGAACLCNACGLFFRKLILRFGRAAAKRYMEQIKGTGTKRRIPKELTGTVRF
SIO_010081: YIR013C
subclass of: SO_0000673
so part of: YIR013C
location: complement(380019..380384)
location: region:380019-380384:-1
so has part: feature:380019-380384:-1:exon

NP_012278.3
type: Protein
SIO_000068: ncbiprotein

S000001452
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:380019-380384:-1:exon

YIR014W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: VLD1
locus tag: YIR014W
so part of: sequence
location: <381086..>381814
location: region:381086-381814:1
so has part: feature:381086-381814:1:exon
subclass of: SO_0000010

854831
type: Gene
SIO_000068: ncbigene

position:381086:1
position: 381086
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:381814:1
position: 381814
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:381086-381814:1:exon

YIR014W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: VLD1
locus tag: YIR014W
product: Vld1p
transcript id: NM_001179536.3
SIO_010081: YIR014W
subclass of: SO_0000673
so part of: YIR014W
location: <381086..>381814
location: region:381086-381814:1
so has part: feature:381086-381814:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:381086-381814:1:exon

YIR014W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: VLD1
locus tag: YIR014W
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0044695 Dsc E3 ubiquitin ligase complex [PMID:29355480]
experiment: EXISTENCE:mutant phenotype:GO:0031503 protein-containing complex localization [PMID:29355480]
note: Component of Dsc E3 ligase complex in vacuolar membranes; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; expression directly regulated by the metabolic and meiotic transcriptional regulator Ume6p; YIR014W is a non-essential gene
codon start: 1
product: Vld1p
translation: MLHLEDDNGRQRSVIANLQKFVYCCLYLRFIKDGSLFLILLGWIISSLCDFIQELTLRYLKKNYLEVGRDNDQEDDESLAIRGLETPIVRMIINKAIRYYQGLILLETAYCIVYHIRLDVSRDICSKPYGFVIMLLIREFTCPVPTAFPSKLLLVLLDILLLFCQIVIINGSLSSSLQNVKLIVKELNAEEEGALNILKLNTWHMDATGPELIVLKNHDKSIPQQADGDDATEITPLLNIAE
SIO_010081: YIR014W
subclass of: SO_0000673
so part of: YIR014W
location: 381086..381814
location: region:381086-381814:1
so has part: feature:381086-381814:1:exon

NP_012279.4
type: Protein
SIO_000068: ncbiprotein

S000001453
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:381086-381814:1:exon

YIR015W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RPR2
locus tag: YIR015W
so part of: sequence
location: <381948..>382382
location: region:381948-382382:1
so has part: feature:381948-382382:1:exon
subclass of: SO_0000010

854832
type: Gene
SIO_000068: ncbigene

position:381948:1
position: 381948
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:382382:1
position: 382382
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:381948-382382:1:exon

YIR015W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RPR2
locus tag: YIR015W
product: ribonuclease P protein subunit RPR2
transcript id: NM_001179537.1
SIO_010081: YIR015W
subclass of: SO_0000673
so part of: YIR015W
location: <381948..>382382
location: region:381948-382382:1
so has part: feature:381948-382382:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:381948-382382:1:exon

YIR015W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RPR2
locus tag: YIR015W
EC number: 3.1.26.5
experiment: EXISTENCE:direct assay:GO:0004526 ribonuclease P activity [PMID:19095620]
experiment: EXISTENCE:direct assay:GO:0005655 nucleolar ribonuclease P complex [PMID:19095620|PMID:9620854]
experiment: EXISTENCE:direct assay:GO:0034965 intronic box C/D RNA processing [PMID:18713869]
experiment: EXISTENCE:mutant phenotype:GO:0008033 tRNA processing [PMID:9620854]
note: Subunit of nuclear RNase P; nuclear RNase P cleaves tRNA precursors to generate mature 5' ends and facilitates turnover of nuclear RNAs; not shared between RNase MRP and RNase P, in contrast to all other RNase P protein subunits; protein abundance increases in response to DNA replication stress
codon start: 1
product: ribonuclease P protein subunit RPR2
translation: MGKKAHGGKMKPEIDENGTLLVPPPRTIANQDHFHRLNYLYQISAYQTRARQKARTDAHTPLARNYIKSMDLISKKTKTSLLPTIKRTICKKCHRLLWTPKKLEITSDGALSVMCGCGTVKRFNIGADPNYRTYSEREGNLLNS
SIO_010081: YIR015W
subclass of: SO_0000673
so part of: YIR015W
location: 381948..382382
location: region:381948-382382:1
so has part: feature:381948-382382:1:exon

NP_012280.1
type: Protein
SIO_000068: ncbiprotein

S000001454
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:381948-382382:1:exon

YIR016W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YIR016W
so part of: sequence
location: <382628..>383425
location: region:382628-383425:1
so has part: feature:382628-383425:1:exon
subclass of: SO_0000010

854833
type: Gene
SIO_000068: ncbigene

position:382628:1
position: 382628
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:383425:1
position: 383425
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:382628-383425:1:exon

YIR016W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YIR016W
product: uncharacterized protein
transcript id: NM_001179538.1
SIO_010081: YIR016W
subclass of: SO_0000673
so part of: YIR016W
location: <382628..>383425
location: region:382628-383425:1
so has part: feature:382628-383425:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:382628-383425:1:exon

YIR016W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YIR016W
note: hypothetical protein; expression directly regulated by the metabolic and meiotic transcriptional regulator Ume6p; overexpression causes a cell cycle delay or arrest; non-essential gene; YIR016W has a paralog, YOL036W, that arose from the whole genome duplication
codon start: 1
product: uncharacterized protein
translation: MSGTRCLLGVGLPVDVTATETLTHDEQGPGVEPGPCSRGSSIDGLLPSLLGPHDDVDDDSAAFHKYMTLSRDGAGAIHAPSLVEDASRNDDDDDDEDDDDSSMSRDLSKALDMSSSSSSSPRVQSRRHRSSVSAISAILHQGKSGREDITGSLSVPAEQEKLSFLAKASSIFFRRNSMPRDKHTHSVCPASRPDSERFIVTSAAAQSLRRQQQLEDAQYARVITNFRTIGWCSPSEIESVEYKRSLINAEWDEKISLLSHAQCYK
SIO_010081: YIR016W
subclass of: SO_0000673
so part of: YIR016W
location: 382628..383425
location: region:382628-383425:1
so has part: feature:382628-383425:1:exon

NP_012281.1
type: Protein
SIO_000068: ncbiprotein

S000001455
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:382628-383425:1:exon

YIR017C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MET28
locus tag: YIR017C
so part of: sequence
location: complement(<383556..>384119)
location: region:383556-384119:-1
so has part: feature:383556-384119:-1:exon
subclass of: SO_0000010

854834
type: Gene
SIO_000068: ncbigene

position:383556:-1
position: 383556
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:384119:-1
position: 384119
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:383556-384119:-1:exon

YIR017C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MET28
locus tag: YIR017C
product: Met28p
transcript id: NM_001179539.3
SIO_010081: YIR017C
subclass of: SO_0000673
so part of: YIR017C
location: complement(<383556..>384119)
location: region:383556-384119:-1
so has part: feature:383556-384119:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:383556-384119:-1:exon

YIR017C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MET28
locus tag: YIR017C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding [PMID:8665859]
experiment: EXISTENCE:direct assay:GO:0089713 Cbf1-Met4-Met28 complex [PMID:8665859|PMID:9171357]
experiment: EXISTENCE:direct assay:GO:2000679 positive regulation of transcription regulatory region DNA binding [PMID:9171357]
experiment: EXISTENCE:mutant phenotype:GO:0006357 regulation of transcription by RNA polymerase II [PMID:8665859]
experiment: EXISTENCE:mutant phenotype:GO:0031335 regulation of sulfur amino acid metabolic process [PMID:8665859]
experiment: EXISTENCE:physical interaction:GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding [PMID:8665859]
note: bZIP transcriptional activator in the Cbf1p-Met4p-Met28p complex; participates in the regulation of sulfur metabolism
codon start: 1
product: Met28p
translation: MSAKQGWEKKSTNIDIASRKGMNVNNLSEHLQNLISSDSELGSRLLSLLLVSSGNAEELISMINNGQDVSQFKKLREPRKGKVAATTAVVVKEEEAPVSTSNELDKIKQERRRKNTEASQRFRIRKKQKNFENMNKLQNLNTQINKLRDRIEQLNKENEFWKAKLNDINEIKSLKLLNDIKRRNMGR
SIO_010081: YIR017C
subclass of: SO_0000673
so part of: YIR017C
location: complement(383556..384119)
location: region:383556-384119:-1
so has part: feature:383556-384119:-1:exon

NP_012282.3
type: Protein
SIO_000068: ncbiprotein

S000001456
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:383556-384119:-1:exon

YIR018W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: YAP5
locus tag: YIR018W
so part of: sequence
location: <384609..>385346
location: region:384609-385346:1
so has part: feature:384609-385346:1:exon
subclass of: SO_0000010

854835
type: Gene
SIO_000068: ncbigene

position:384609:1
position: 384609
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:385346:1
position: 385346
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:384609-385346:1:exon

YIR018W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: YAP5
locus tag: YIR018W
product: Yap5p
transcript id: NM_001179540.1
SIO_010081: YIR018W
subclass of: SO_0000673
so part of: YIR018W
location: <384609..>385346
location: region:384609-385346:1
so has part: feature:384609-385346:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:384609-385346:1:exon

YIR018W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: YAP5
locus tag: YIR018W
experiment: EXISTENCE:direct assay:GO:0000785 chromatin [PMID:12464632]
experiment: EXISTENCE:direct assay:GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific [PMID:18287073]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:18070921]
experiment: EXISTENCE:direct assay:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:9372930]
experiment: EXISTENCE:mutant phenotype:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:18287073]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:18287073|PMID:18070921]
note: Basic leucine zipper (bZIP) iron-sensing transcription factor; senses high-iron conditions via two Fe/S clusters bound to its activator domain; involved in diauxic shift; YAP5 has a paralog, YAP7, that arose from the whole genome duplication
codon start: 1
product: Yap5p
translation: MALPLIKPKESEESHLALLSKIHVSKNWKLPPRLPHRAAQRRKRVHRLHEDYETEENDEELQKKKRQNRDAQRAYRERKNNKLQVLEETIESLSKVVKNYETKLNRLQNELQAKESENHALKQKLETLTLKQASVPAQDPILQNLIENFKPMKAIPIKYNTAIKRHQHSTELPSSVKCGFCNDNTTCVCKELETDHRKSDDGVATEQKDMSMPHAECNNKDNPNGLCSNCTNIDKSCIDIRSIIH
SIO_010081: YIR018W
subclass of: SO_0000673
so part of: YIR018W
location: 384609..385346
location: region:384609-385346:1
so has part: feature:384609-385346:1:exon

NP_012283.1
type: Protein
SIO_000068: ncbiprotein

S000001457
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:384609-385346:1:exon

YIR018C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YIR018C-A
so part of: sequence
location: complement(<385564..>385701)
location: region:385564-385701:-1
so has part: feature:385564-385701:-1:exon
subclass of: SO_0000010

1466494
type: Gene
SIO_000068: ncbigene

position:385564:-1
position: 385564
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:385701:-1
position: 385701
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:385564-385701:-1:exon

YIR018C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YIR018C-A
product: uncharacterized protein
transcript id: NM_001184655.1
SIO_010081: YIR018C-A
subclass of: SO_0000673
so part of: YIR018C-A
location: complement(<385564..>385701)
location: region:385564-385701:-1
so has part: feature:385564-385701:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:385564-385701:-1:exon

YIR018C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YIR018C-A
note: hypothetical protein; identified by expression profiling and mass spectrometry
codon start: 1
product: uncharacterized protein
translation: MPSDYTSHYPVILIKKKKKKIAGMYRHSKRYLEIMSTASAQFVGN
SIO_010081: YIR018C-A
subclass of: SO_0000673
so part of: YIR018C-A
location: complement(385564..385701)
location: region:385564-385701:-1
so has part: feature:385564-385701:-1:exon

NP_878099.1
type: Protein
SIO_000068: ncbiprotein

S000028837
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:385564-385701:-1:exon

YIR019C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MUC1
alternative label: STA4
gene: FLO11
locus tag: YIR019C
gene synonym: MUC1; STA4
so part of: sequence
location: complement(<389572..>393675)
location: region:389572-393675:-1
so has part: feature:389572-393675:-1:exon
subclass of: SO_0000010

854836
type: Gene
SIO_000068: ncbigene

position:389572:-1
position: 389572
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:393675:-1
position: 393675
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:389572-393675:-1:exon

YIR019C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MUC1
alternative label: STA4
gene: FLO11
locus tag: YIR019C
gene synonym: MUC1; STA4
product: Flo11p
transcript id: NM_001179541.3
SIO_010081: YIR019C
subclass of: SO_0000673
so part of: YIR019C
location: complement(<389572..>393675)
location: region:389572-393675:-1
so has part: feature:389572-393675:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:389572-393675:-1:exon

YIR019C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MUC1
alternative label: STA4
gene: FLO11
locus tag: YIR019C
gene synonym: MUC1; STA4
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005576 extracellular region [PMID:20619652]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:11027318]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:19799621]
experiment: EXISTENCE:direct assay:GO:0030447 filamentous growth [PMID:12072450]
experiment: EXISTENCE:mutant phenotype:GO:0000128 flocculation [PMID:19160455]
experiment: EXISTENCE:mutant phenotype:GO:0001403 invasive growth in response to glucose limitation [PMID:12150916|PMID:19087208|PMID:8710886]
experiment: EXISTENCE:mutant phenotype:GO:0007124 pseudohyphal growth [PMID:8710886]
experiment: EXISTENCE:mutant phenotype:GO:0043709 cell adhesion involved in single-species biofilm formation [PMID:11157168]
experiment: EXISTENCE:mutant phenotype:GO:0044011 single-species biofilm formation on inanimate substrate [PMID:11157168|PMID:19160455]
experiment: EXISTENCE:mutant phenotype:GO:0090606 single-species surface biofilm formation [PMID:12024013|PMID:19160455]
experiment: EXISTENCE:mutant phenotype:GO:0098609 cell-cell adhesion [PMID:19160455|PMID:21875945]
note: GPI-anchored cell surface glycoprotein (flocculin); required for pseudohyphal and invasive growth, flocculation, and biofilm formation; major determinant of colony morphology; QTL that controls chronological life span; carries intragenic tandem repeats that are expanded in different strains; required for formation of fibrous interconnections between cells; role in co-flocculation with other yeast species; cleaved and shed from cells, contributing to their surface properties
codon start: 1
product: Flo11p
translation: MQRPFLLAYLVLSLLFNSALGFPTALVPRGSSEGTSCNSIVNGCPNLDFNWHMDQQNIMQYTLDVTSVSWVQDNTYQITIHVKGKENIDLKYLWSLKIIGVTGPKGTVQLYGYNENTYLIDNPTDFTATFEVYATQDVNSCQVWMPNFQIQFEYLQGSAAQYASSWQWGTTSFDLSTGCNNYDNQGHSQTDFPGFYWNIDCDNNCGGTKSSTTTSSTSESSTTTSSTSESSTTTSSTSESSTTTSSTSESSTSSSTTAPATPTTTSCTKEKPTPPTTTSCTKEKPTPPHHDTTPCTKKKTTTSKTCTKKTTTPVPTPSSSTTESSSAPVPTPSSSTTESSSAPVTSSTTESSSAPVPTPSSSTTESSSAPVTSSTTESSSAPVTSSTTESSSAPVPTPSSSTTESSSAPVTSSTTESSSAPVTSSTTESSSAPVTSSTTESSSAPVTSSTTESSSAPVPTPSSSTTESSSAPVTSSTTESSSAPVPTPSSSTTESSSAPVTSSTTESSSAPVPTPSSSTTESSSAPAPTPSSSTTESSSAPVTSSTTESSSAPVPTPSSSTTESSSTPVTSSTTESSSAPVPTPSSSTTESSSAPVPTPSSSTTESSSAPAPTPSSSTTESSSAPVTSSTTESSSAPVPTPSSSTTESSSAPVPTPSSSTTESSSAPVPTPSSSTTESSSAPVTSSTTESSSAPVTSSTTESSSAPVPTPSSSTTESSSAPVPTPSSSTTESSSAPVPTPSSSTTESSSAPVTSSTTESSSAPVPTPSSSTTESSSAPVPTPSSSTTESSSAPVPTPSSSTTESSVAPVPTPSSSSNITSSAPSSTPFSSSTESSSVPVPTPSSSTTESSSAPVSSSTTESSVAPVPTPSSSSNITSSAPSSIPFSSTTESFSTGTTVTPSSSKYPGSQTETSVSSTTETTIVPTKTTTSVTTPSTTTITTTVCSTGTNSAGETTSGCSPKTVTTTVPTTTTTSVTTSSTTTITTTVCSTGTNSAGETTSGCSPKTITTTVPCSTSPSETASESTTTSPTTPVTTVVSTTVVTTEYSTSTKPGGEITTTFVTKNIPTTYLTTIAPTPSVTTVTNFTPTTITTTVCSTGTNSAGETTSGCSPKTVTTTVPCSTGTGEYTTEATTLVTTAVTTTVVTTESSTGTNSAGKTTTGYTTKSVPTTYVTTLAPSAPVTPATNAVPTTITTTECSAATNAAGETTSVCSAKTIVSSASAGENTAPSATTPVTTAIPTTVITTESSVGTNSAGETTTGYTTKSIPTTYITTLIPGSNGAKNYETVATATNPISIKTTSQLATTASASSVAPVVTSPSLTGPLQSASGSAVATYSVPSISSTYQGAANIKVLGNFMWLLLALPVVF
SIO_010081: YIR019C
subclass of: SO_0000673
so part of: YIR019C
location: complement(389572..393675)
location: region:389572-393675:-1
so has part: feature:389572-393675:-1:exon

NP_012284.3
type: Protein
SIO_000068: ncbiprotein

S000001458
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:389572-393675:-1:exon

regulatory
type: Feature
subclass of: SO_0000001
RO_0002162: 559292
regulatory class: other
note: Upstream open reading frame (uORF) in 5' untranslated region of FLO11 gene, regulate translation
so part of: sequence
location: complement(393718..393732)
location: region:393718-393732:-1
so has part: feature:393718-393732:-1:region

position:393718:-1
position: 393718
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:393732:-1
position: 393732
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:393718-393732:-1:region

YNCI0012
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ICR1
locus tag: YNCI0012
so part of: sequence
location: complement(393884..397082)
location: region:393884-397082:-1
so has part: feature:393884-397082:-1:exon
subclass of: SO_0000011

9164906
type: Gene
SIO_000068: ncbigene

position:393884:-1
position: 393884
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:397082:-1
position: 397082
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:393884-397082:-1:exon

YNCI0012
type: Non Coding RNA
subclass of: SO_0000655
RO_0002162: 559292
nc RNA class: other
gene: ICR1
locus tag: YNCI0012
product: ICR1
experiment: EXISTENCE:curator inference:GO:0005634 nucleus [PMID:19805129]
experiment: EXISTENCE:direct assay:GO:0006357 regulation of transcription by RNA polymerase II [PMID:19805129]
experiment: EXISTENCE:genetic interaction:GO:0006357 regulation of transcription by RNA polymerase II [PMID:19805129]
experiment: EXISTENCE:mutant phenotype:GO:0006357 regulation of transcription by RNA polymerase II [PMID:19805129]
note: Long intergenic regulatory ncRNA; has a key role in regulating transcription of the nearby protein-coding ORF FLO11; initiated far upstream from FLO11 and transcribed across much of the large promoter of FLO11, repressing FLO11 transcription in cis
transcript id: NR_132191.1
SIO_010081: YNCI0012
subclass of: SO_0000673
so part of: YNCI0012
location: complement(393884..397082)
location: region:393884-397082:-1
so has part: feature:393884-397082:-1:exon

S000132612
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:393884-397082:-1:exon

YIR020C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YIR020C
so part of: sequence
location: complement(<394255..>394557)
location: region:394255-394557:-1
so has part: feature:394255-394557:-1:exon
subclass of: SO_0000010

854837
type: Gene
SIO_000068: ncbigene

position:394255:-1
position: 394255
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:394557:-1
position: 394557
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:394255-394557:-1:exon

YIR020C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YIR020C
product: uncharacterized protein
transcript id: NM_001270752.1
SIO_010081: YIR020C
subclass of: SO_0000673
so part of: YIR020C
location: complement(<394255..>394557)
location: region:394255-394557:-1
so has part: feature:394255-394557:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:394255-394557:-1:exon

YIR020C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YIR020C
note: hypothetical protein; mRNA identified as translated by ribosome profiling data; SWAT-GFP fusion protein localizes to the endoplasmic reticulum
codon start: 1
product: uncharacterized protein
translation: MTFFLKRKISFFLSGIAQTFLFLPILLNRSVIHVVFLTVVLGHRIPWDSVIRCNNTGTTHSAVSSRTELLLPIGGVINNWKRRAWNGFSIQWIWRYSFVY
SIO_010081: YIR020C
subclass of: SO_0000673
so part of: YIR020C
location: complement(394255..394557)
location: region:394255-394557:-1
so has part: feature:394255-394557:-1:exon

NP_001257681.1
type: Protein
SIO_000068: ncbiprotein

S000001459
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:394255-394557:-1:exon

YNCI0013W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PWR1
locus tag: YNCI0013W
so part of: sequence
location: 395999..396939
location: region:395999-396939:1
so has part: feature:395999-396939:1:exon
subclass of: SO_0000011

9164905
type: Gene
SIO_000068: ncbigene

position:395999:1
position: 395999
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:396939:1
position: 396939
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:395999-396939:1:exon

YNCI0013W
type: Non Coding RNA
subclass of: SO_0000655
RO_0002162: 559292
nc RNA class: other
gene: PWR1
locus tag: YNCI0013W
product: PWR1
experiment: EXISTENCE:curator inference:GO:0005634 nucleus [PMID:19805129]
experiment: EXISTENCE:direct assay:GO:0006357 regulation of transcription by RNA polymerase II [PMID:19805129]
experiment: EXISTENCE:mutant phenotype:GO:0006357 regulation of transcription by RNA polymerase II [PMID:19805129]
note: Intergenic regulatory ncRNA; one of two long ncRNAs that play key roles in regulating transcription of the nearby protein-coding ORF FLO11; PWR1 promotes FLO11 transcription by interfering with ncRNA ICR1, which is transcribed across the FLO11 promoter
transcript id: NR_132192.1
SIO_010081: YNCI0013W
subclass of: SO_0000673
so part of: YNCI0013W
location: 395999..396939
location: region:395999-396939:1
so has part: feature:395999-396939:1:exon

S000132614
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:395999-396939:1:exon

YIR021W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PET157
gene: MRS1
locus tag: YIR021W
gene synonym: PET157
so part of: sequence
location: <397294..>398385
location: region:397294-398385:1
so has part: feature:397294-398385:1:exon
subclass of: SO_0000010

854839
type: Gene
SIO_000068: ncbigene

position:397294:1
position: 397294
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:398385:1
position: 398385
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:397294-398385:1:exon

YIR021W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PET157
gene: MRS1
locus tag: YIR021W
gene synonym: PET157
product: Mrs1p
transcript id: NM_001179543.3
SIO_010081: YIR021W
subclass of: SO_0000673
so part of: YIR021W
location: <397294..>398385
location: region:397294-398385:1
so has part: feature:397294-398385:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:397294-398385:1:exon

YIR021W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PET157
gene: MRS1
locus tag: YIR021W
gene synonym: PET157
experiment: EXISTENCE:curator inference:GO:0005739 mitochondrion [PMID:2443348]
experiment: EXISTENCE:direct assay:GO:0000372 Group I intron splicing [PMID:11773622]
experiment: EXISTENCE:direct assay:GO:0003723 RNA binding [PMID:11773622]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095|PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:1990904 ribonucleoprotein complex [PMID:12924947]
experiment: EXISTENCE:mutant phenotype:GO:0000963 mitochondrial RNA processing [PMID:2443348]
note: Splicing protein; required for splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA; MRS1 has a paralog, CCE1, that arose from the whole genome duplication
codon start: 1
product: Mrs1p
translation: MSPKNITRSVIPAIDLYCRKANFKTLKSLSMILGSKKEWYDTKKAPLRTFLVSRCGIFEQLRGRLVEDGKVNLFSVFLTNDSFSFCKMTVDDKFNTSLVDWQKIPFDSTFATDRRQNISLLPVDTLFATEKIISILGVSPNMTNLVSIERERSDLVDFNCKLQSNILEHLLYAKCQGVYVTSTNEKARLLAAVCNPEFIDTFWCELTPIRVSLKENPSISVPREYQMYDPVVRATIKEVVTKRLLRSAFDNDIDPLMCLHLDKGWKLKFPILSSTTGLNFSLKDCLSLDTGKDASDMTEVFLATMESSKVLRTYSNLVDIVMKDNGRLDSGVLKQFNDYVKQEKLNLQHFQAGSSKFLKGAKI
SIO_010081: YIR021W
subclass of: SO_0000673
so part of: YIR021W
location: 397294..398385
location: region:397294-398385:1
so has part: feature:397294-398385:1:exon

NP_012287.3
type: Protein
SIO_000068: ncbiprotein

S000001460
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:397294-398385:1:exon

YIR021W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YIR021W-A
so part of: sequence
location: <398514..>398726
location: region:398514-398726:1
so has part: feature:398514-398726:1:exon
subclass of: SO_0000010

1466495
type: Gene
SIO_000068: ncbigene

position:398514:1
position: 398514
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:398726:1
position: 398726
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:398514-398726:1:exon

YIR021W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YIR021W-A
product: uncharacterized protein
transcript id: NM_001184656.1
SIO_010081: YIR021W-A
subclass of: SO_0000673
so part of: YIR021W-A
location: <398514..>398726
location: region:398514-398726:1
so has part: feature:398514-398726:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:398514-398726:1:exon

YIR021W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YIR021W-A
note: hypothetical protein; identified by expression profiling and mass spectrometry
codon start: 1
product: uncharacterized protein
translation: MSFSVSCKTPKTTKLLVSSISESAVALIIITIRILFSIGKSDFKKIISKEINGAETIYYRNIPESKPQGS
SIO_010081: YIR021W-A
subclass of: SO_0000673
so part of: YIR021W-A
location: 398514..398726
location: region:398514-398726:1
so has part: feature:398514-398726:1:exon

NP_878100.1
type: Protein
SIO_000068: ncbiprotein

S000028838
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:398514-398726:1:exon

YIR022W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SEC11
locus tag: YIR022W
so part of: sequence
location: <398733..>399236
location: region:398733-399236:1
so has part: feature:398733-399236:1:exon
subclass of: SO_0000010

854840
type: Gene
SIO_000068: ncbigene

position:398733:1
position: 398733
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:399236:1
position: 399236
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:398733-399236:1:exon

YIR022W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SEC11
locus tag: YIR022W
product: signal peptidase complex catalytic subunit SEC11
transcript id: NM_001179544.1
SIO_010081: YIR022W
subclass of: SO_0000673
so part of: YIR022W
location: <398733..>399236
location: region:398733-399236:1
so has part: feature:398733-399236:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:398733-399236:1:exon

YIR022W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SEC11
locus tag: YIR022W
EC number: 3.4.21.89
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:11058593]
experiment: EXISTENCE:direct assay:GO:0005787 signal peptidase complex [PMID:8910564|PMID:1846444]
experiment: EXISTENCE:direct assay:GO:0006465 signal peptide processing [PMID:10206957]
experiment: EXISTENCE:mutant phenotype:GO:0006465 signal peptide processing [PMID:10206957|PMID:3283143]
experiment: EXISTENCE:mutant phenotype:GO:0008233 peptidase activity [PMID:10206957]
experiment: EXISTENCE:mutant phenotype:GO:0045047 protein targeting to ER [PMID:3283143]
note: 18kDa catalytic subunit of the Signal Peptidase Complex (SPC); the Signal Peptidase Complex cleaves the signal sequence of proteins targeted to the endoplasmic reticulum; other members are Spc1p, Spc2p, Spc3p, and Sec11p
codon start: 1
product: signal peptidase complex catalytic subunit SEC11
translation: MNLRFELQKLLNVCFLFASAYMFWQGLAIATNSASPIVVVLSGSMEPAFQRGDILFLWNRNTFNQVGDVVVYEVEGKQIPIVHRVLRQHNNHADKQFLLTKGDNNAGNDISLYANKKIYLNKSKEIVGTVKGYFPQLGYITIWISENKYAKFALLGMLGLSALLGGE
SIO_010081: YIR022W
subclass of: SO_0000673
so part of: YIR022W
location: 398733..399236
location: region:398733-399236:1
so has part: feature:398733-399236:1:exon

NP_012288.1
type: Protein
SIO_000068: ncbiprotein

S000001461
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:398733-399236:1:exon

YIR023W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: UGA35
gene: DAL81
locus tag: YIR023W
gene synonym: UGA35
so part of: sequence
location: <399777..>402689
location: region:399777-402689:1
so has part: feature:399777-402689:1:exon
subclass of: SO_0000010

854841
type: Gene
SIO_000068: ncbigene

position:399777:1
position: 399777
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:402689:1
position: 402689
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:399777-402689:1:exon

YIR023W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: UGA35
gene: DAL81
locus tag: YIR023W
gene synonym: UGA35
product: Dal81p
transcript id: NM_001179545.3
SIO_010081: YIR023W
subclass of: SO_0000673
so part of: YIR023W
location: <399777..>402689
location: region:399777-402689:1
so has part: feature:399777-402689:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:399777-402689:1:exon

YIR023W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: UGA35
gene: DAL81
locus tag: YIR023W
gene synonym: UGA35
experiment: EXISTENCE:curator inference:GO:0005634 nucleus [PMID:21515579]
experiment: EXISTENCE:direct assay:GO:0003713 transcription coactivator activity [PMID:21515579]
experiment: EXISTENCE:direct assay:GO:0051123 RNA polymerase II preinitiation complex assembly [PMID:21515579]
experiment: EXISTENCE:mutant phenotype:GO:0001080 nitrogen catabolite activation of transcription from RNA polymerase II promoter [PMID:7899074]
experiment: EXISTENCE:mutant phenotype:GO:0003713 transcription coactivator activity [PMID:21515579]
experiment: EXISTENCE:mutant phenotype:GO:0051123 RNA polymerase II preinitiation complex assembly [PMID:21515579]
experiment: EXISTENCE:mutant phenotype:GO:1901714 positive regulation of urea catabolic process [PMID:2406136]
experiment: EXISTENCE:mutant phenotype:GO:1901717 positive regulation of gamma-aminobutyric acid catabolic process [PMID:2406136]
experiment: EXISTENCE:physical interaction:GO:0001080 nitrogen catabolite activation of transcription from RNA polymerase II promoter [PMID:10906145]
note: Positive regulator of genes in multiple nitrogen degradation pathways; contains DNA binding domain but does not appear to bind the dodecanucleotide sequence present in the promoter region of many genes involved in allantoin catabolism
codon start: 1
product: Dal81p
translation: MDPHQSPADNAASPTKSVKATTKNSSTNNNVNSNNSNNNSNHDILNFNDNYTTILQHLANDHPNILREKGGSQQQQHQQQQQQQQQQQQQQQQQSLDTLLHHYQSLLSKSDNAIAFDDNVSNSADHNGSNSNNNNNNNDISSPGNLMGSCNQCRLKKTKCNYFPDLGNCLECETSRTKCTFSIAPNYLKRTSSGANNNMPTSSNSKRMKNFEDYSNRLPSSMLYRHQQQQQQQQQQQRIQYPRSSFFVGPASVFDLNLTKHVRLDNVDQIQLSKTLSLRKVSPTAQFILQDDFDTTLHSKQEYEVDLVENLVHPHGHLLVEIFFKLIHPFLPILHERVFLEKYSRSYRELTAPLLASIYSLALQYWDFHPALLGFPKPDVTAQLNNIALETFYARVGRPKLSIIQTGLLILQCRSECHNNWVLCSSVVALAEELGLGVECNDWKLPKWEKDLRKRLAWAVWLMDKWCALNEGRQSHLILGRNWMIKLLNFDDFPLNSPTILNSLQNDQSGSSPSSSNDVKNHQIAFGNLPIFNINPTLEDFKNGTLMFQQMVSLSIILGEIMDTFYTQGSMTINKSIEQVLKLAKPLQLKLREWYHSLPKNLSMSYATPQKLNSNSTLTLAYFATEITLHRKIICALNPQTPKELVQVCRTAARTRLVAAIEFIRDLKNEHINAFWYNCSTGNLMLIGTFAALLYVTSATKEEAMIFRDYVRNYTWVLKIGSKYFDKLSNALNNMHLLFAQIPGLLTDEPVVVSPNSNINSVNPQRSGVQSQIPIQFNVGSPAMTEQGSPLNQWKNLPQEILQQLNSFPNGTTSTTTPVNPTSRQTQLESQGSPAINSANNNSNNTPLPFAPNKSSKKTSQSSPNVTPSHMSRHPPSNTSSPRVNSSTNVNSNTQMNASPLTSINETRQESGDAADEKTAGRERTANEESSTELKDDNPNSNQETSATGNQTIKMNDDKNVTINTRETPL
SIO_010081: YIR023W
subclass of: SO_0000673
so part of: YIR023W
location: 399777..402689
location: region:399777-402689:1
so has part: feature:399777-402689:1:exon

NP_012289.3
type: Protein
SIO_000068: ncbiprotein

S000001462
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:399777-402689:1:exon

YIR024C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: INA22
locus tag: YIR024C
so part of: sequence
location: complement(<402841..>403491)
location: region:402841-403491:-1
so has part: feature:402841-403491:-1:exon
subclass of: SO_0000010

854842
type: Gene
SIO_000068: ncbigene

position:402841:-1
position: 402841
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:403491:-1
position: 403491
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:402841-403491:-1:exon

YIR024C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: INA22
locus tag: YIR024C
product: Ina22p
transcript id: NM_001179546.1
SIO_010081: YIR024C
subclass of: SO_0000673
so part of: YIR024C
location: complement(<402841..>403491)
location: region:402841-403491:-1
so has part: feature:402841-403491:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:402841-403491:-1:exon

YIR024C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: INA22
locus tag: YIR024C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:14562095|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005743 mitochondrial inner membrane [PMID:24942160]
experiment: EXISTENCE:direct assay:GO:1990524 INA complex [PMID:24942160]
experiment: EXISTENCE:genetic interaction:GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly [PMID:24942160]
experiment: EXISTENCE:mutant phenotype:GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly [PMID:24942160]
experiment: EXISTENCE:physical interaction:GO:1990524 INA complex [PMID:24942160]
note: F1F0 ATP synthase peripheral stalk assembly factor; subunit of the matrix-exposed inner mitochondrial membrane localized INA complex (Ina22p-Ina17p) involved in assembly of the F1F0 peripheral stalk; co-purifies with Aim43p, ATP synthase subunits, and cytochrome bc1 complex assembly factors; interacts with Arh1p, a mitochondrial oxidoreductase; deletion mutant has a respiratory growth defect
codon start: 1
product: Ina22p
translation: MFMARQVLRNGLFLRSLAPIKITARTVASANAGIKRKSRFDKTMIKPLLLVMIFGSILNAVIAEKRNIIDMERKYKLKLDKLKELIRRVHDNNGKVDFDADDELKLVNLRLGIVGKNATGMKEDETDIVVPKEESLEEIWQSIIDEAKKEVIEKTPDAGVKNKEGIVTDLNVLKDLEKSKKEDEKVYLSGDVHMMMNQPGDLNEIAKEHDKIPKFL
SIO_010081: YIR024C
subclass of: SO_0000673
so part of: YIR024C
location: complement(402841..403491)
location: region:402841-403491:-1
so has part: feature:402841-403491:-1:exon

NP_012290.1
type: Protein
SIO_000068: ncbiprotein

S000001463
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:402841-403491:-1:exon

YIR025W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MND2
locus tag: YIR025W
so part of: sequence
location: <403659..>404765
location: region:403659-404765:1
so has part: feature:403659-404765:1:exon
subclass of: SO_0000010

854843
type: Gene
SIO_000068: ncbigene

position:403659:1
position: 403659
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:404765:1
position: 404765
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:403659-404765:1:exon

YIR025W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MND2
locus tag: YIR025W
product: Mnd2p
transcript id: NM_001179547.1
SIO_010081: YIR025W
subclass of: SO_0000673
so part of: YIR025W
location: <403659..>404765
location: region:403659-404765:1
so has part: feature:403659-404765:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:403659-404765:1:exon

YIR025W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MND2
locus tag: YIR025W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:15797380]
experiment: EXISTENCE:direct assay:GO:0005680 anaphase-promoting complex [PMID:12609981|PMID:12574115]
experiment: EXISTENCE:direct assay:GO:1902499 positive regulation of protein autoubiquitination [PMID:22940250]
experiment: EXISTENCE:direct assay:GO:1904667 negative regulation of ubiquitin protein ligase activity [PMID:15797379]
experiment: EXISTENCE:direct assay:GO:1990948 ubiquitin ligase inhibitor activity [PMID:15797379]
experiment: EXISTENCE:genetic interaction:GO:1904667 negative regulation of ubiquitin protein ligase activity [PMID:15797379]
experiment: EXISTENCE:genetic interaction:GO:1905785 negative regulation of anaphase-promoting complex-dependent catabolic process [PMID:15797380]
experiment: EXISTENCE:mutant phenotype:GO:0000070 mitotic sister chromatid segregation [PMID:15797379]
experiment: EXISTENCE:mutant phenotype:GO:0007131 reciprocal meiotic recombination [PMID:11470404]
experiment: EXISTENCE:mutant phenotype:GO:0030071 regulation of mitotic metaphase/anaphase transition [PMID:12609981]
experiment: EXISTENCE:mutant phenotype:GO:1902426 deactivation of mitotic spindle assembly checkpoint [PMID:22940250]
experiment: EXISTENCE:mutant phenotype:GO:1902499 positive regulation of protein autoubiquitination [PMID:22940250]
experiment: EXISTENCE:physical interaction:GO:0005680 anaphase-promoting complex [PMID:15797379]
note: Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C); necessary for maintaining sister chromatid cohesion in prophase I of meiosis by inhibiting premature ubiquitination and subsequent degradation of substrates by the APC(Ama1) ubiquitin ligase
codon start: 1
product: Mnd2p
translation: MARALRDISLFNDIRKDQNSAGAKHERYNMRDLRSKKNQHVNGIDDYEDDSLDRFIRRKKSRVVKYIPSLSAYNVFNEFPYYPTSASQLLDGKLDEFLMLSEQYKSRLPKIRKLGWNRFKPIGINKTMYELEMLRSRARAQNAEGNNEEDFRQHDSREEDPRNNGSIGRVILPHILQENEEYDTGEGVTGLHSMPNDSMAILANNSANNSQNEEVSEEDEISYDYDAEFDHVVDEDDNEEGEVPGEGVEGIEVQRERIVPDDLLMRPTSLSRSLQQFVEEAHHLDRNPYDIDSDNDGEDSKVELDMNPDFEDDVGREHDYNSEYSQEPTSYGGITPDLASNWRNWTRERITSLDELMERRARQQRGQD
SIO_010081: YIR025W
subclass of: SO_0000673
so part of: YIR025W
location: 403659..404765
location: region:403659-404765:1
so has part: feature:403659-404765:1:exon

NP_012291.1
type: Protein
SIO_000068: ncbiprotein

S000001464
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:403659-404765:1:exon

YIR026C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: YVH1
locus tag: YIR026C
so part of: sequence
location: complement(<404873..>405967)
location: region:404873-405967:-1
so has part: feature:404873-405967:-1:exon
subclass of: SO_0000010

854844
type: Gene
SIO_000068: ncbigene

position:404873:-1
position: 404873
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:405967:-1
position: 405967
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:404873-405967:-1:exon

YIR026C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: YVH1
locus tag: YIR026C
product: tyrosine protein phosphatase YVH1
transcript id: NM_001179548.3
SIO_010081: YIR026C
subclass of: SO_0000673
so part of: YIR026C
location: complement(<404873..>405967)
location: region:404873-405967:-1
so has part: feature:404873-405967:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:404873-405967:-1:exon

YIR026C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: YVH1
locus tag: YIR026C
EC number: 3.1.3.48
experiment: EXISTENCE:direct assay:GO:0004725 protein tyrosine phosphatase activity [PMID:1334559]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:19797078|PMID:19797079]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:19797078|PMID:19797079|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0010494 cytoplasmic stress granule [PMID:26777405]
experiment: EXISTENCE:direct assay:GO:1990275 preribosome binding [PMID:19797078]
experiment: EXISTENCE:genetic interaction:GO:0000027 ribosomal large subunit assembly [PMID:19797078]
experiment: EXISTENCE:genetic interaction:GO:0000055 ribosomal large subunit export from nucleus [PMID:19797079]
experiment: EXISTENCE:genetic interaction:GO:0030476 ascospore wall assembly [PMID:10464190]
experiment: EXISTENCE:mutant phenotype:GO:0000027 ribosomal large subunit assembly [PMID:19114459|PMID:19797078]
experiment: EXISTENCE:mutant phenotype:GO:0000055 ribosomal large subunit export from nucleus [PMID:19797079]
experiment: EXISTENCE:mutant phenotype:GO:0030476 ascospore wall assembly [PMID:10464190]
experiment: EXISTENCE:mutant phenotype:GO:0051321 meiotic cell cycle [PMID:8896280]
experiment: EXISTENCE:mutant phenotype:GO:2000786 positive regulation of autophagosome assembly [PMID:26125457]
note: Dual specificity protein phosphatase; regulates growth, sporulation, and glycogen accumulation in a cAMP-dependent protein kinase cascade dependent manner; mutants are defective in 60S ribosome assembly; positively regulates pre-autophagosomal structure (PAS) formation upon nitrogen starvation or rapamycin treatment
codon start: 1
product: tyrosine protein phosphatase YVH1
translation: MAGNANSVDEEVTRILGGIYLGGIRPIIDHRPLGAEFNITHILSVIKFQVIPEYLIRKGYTLKNIPIDDDDVTDVLQYFDETNRFIDQCLFPNEVEYSPRLVDFKKKPQRGAVFAHCQAGLSRSVTFIVAYLMYRYGLSLSMAMHAVKRKKPSVEPNENFMEQLHLFEKMGGDFVDFDNPAYKQWKLKQSIKLDPSGSELVSNSGMFKDSESSQDLDKLTEAEKSKVTAVRCKKCRTKLALSTSFIAHDPPSKESSEGHFIKRAANSHRIIDIQESQANCSHFFIEPLKWMQPELQGKQELEGKFSCPGCSSKVGGYNWKGSRCSCGKWVIPAIHLQTSKVDQFPLQSTALPNMVNFESEKVNR
SIO_010081: YIR026C
subclass of: SO_0000673
so part of: YIR026C
location: complement(404873..405967)
location: region:404873-405967:-1
so has part: feature:404873-405967:-1:exon

NP_012292.3
type: Protein
SIO_000068: ncbiprotein

S000001465
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:404873-405967:-1:exon

YIR027C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: DAL1
locus tag: YIR027C
so part of: sequence
location: complement(<406260..>407642)
location: region:406260-407642:-1
so has part: feature:406260-407642:-1:exon
subclass of: SO_0000010

854845
type: Gene
SIO_000068: ncbigene

position:406260:-1
position: 406260
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:407642:-1
position: 407642
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:406260-407642:-1:exon

YIR027C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: DAL1
locus tag: YIR027C
product: allantoinase
transcript id: NM_001179549.3
SIO_010081: YIR027C
subclass of: SO_0000673
so part of: YIR027C
location: complement(<406260..>407642)
location: region:406260-407642:-1
so has part: feature:406260-407642:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:406260-407642:-1:exon

YIR027C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: DAL1
locus tag: YIR027C
EC number: 3.5.2.5
experiment: EXISTENCE:mutant phenotype:GO:0004038 allantoinase activity [PMID:4604238|PMID:1803816]
experiment: EXISTENCE:mutant phenotype:GO:0009442 allantoin assimilation pathway [PMID:1803816|PMID:4604238]
note: Allantoinase; converts allantoin to allantoate in the first step of allantoin degradation; expression sensitive to nitrogen catabolite repression
codon start: 1
product: allantoinase
translation: MPINAITSDHVIINGANKPATIVYSTESGTILDVLEGSVVMEKTEITKYEIHTLENVSPCTILPGLVDSHVHLNEPGRTSWEGFETGTQAAISGGVTTVVDMPLNAIPPTTNVENFRIKLEAAEGQMWCDVGFWGGLVPHNLPDLIPLVKAGVRGFKGFLLDSGVEEFPPIGKEYIEEALKVLAEEDTMMMFHAELPKAHEDQQQPEQSHREYSSFLSSRPDSFEIDAINLILECLRARNGPVPPVHIVHLASMKAIPLIRKARASGLPVTTETCFHYLCIAAEQIPDGATYFKCCPPIRSESNRQGLWDALREGVIGSVVSDHSPCTPELKNLQKGDFFDSWGGIASVGLGLPLMFTQGCSLVDIVTWCCKNTSHQVGLSHQKGTIAPGYDADLVVFDTASKHKISNSSVYFKNKLTAYNGMTVKGTVLKTILRGQVVYTNANGVSKTPLGQTLLDSRR
SIO_010081: YIR027C
subclass of: SO_0000673
so part of: YIR027C
location: complement(406260..407642)
location: region:406260-407642:-1
so has part: feature:406260-407642:-1:exon

NP_012293.3
type: Protein
SIO_000068: ncbiprotein

S000001466
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:406260-407642:-1:exon

YIR028W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: DAL4
locus tag: YIR028W
so part of: sequence
location: <408468..>410375
location: region:408468-410375:1
so has part: feature:408468-410375:1:exon
subclass of: SO_0000010

854846
type: Gene
SIO_000068: ncbigene

position:408468:1
position: 408468
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:410375:1
position: 410375
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:408468-410375:1:exon

YIR028W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: DAL4
locus tag: YIR028W
product: allantoin permease
transcript id: NM_001179550.3
SIO_010081: YIR028W
subclass of: SO_0000673
so part of: YIR028W
location: <408468..>410375
location: region:408468-410375:1
so has part: feature:408468-410375:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:408468-410375:1:exon

YIR028W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: DAL4
locus tag: YIR028W
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0000256 allantoin catabolic process [PMID:385448]
experiment: EXISTENCE:mutant phenotype:GO:0005274 allantoin:proton symporter activity [PMID:385448]
experiment: EXISTENCE:mutant phenotype:GO:0015720 allantoin transport [PMID:3549700|PMID:385448]
note: Allantoin permease; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation
codon start: 1
product: allantoin permease
translation: MANDALSAIFSNPSRKGVQPSTSIVSYTNNEDDIIDVENGKFNKNKNINTNVYVDNSSIEESEVVPLPETKSIWSKIYYDFIVLDKTTLNVSLKESFLYNRDLKPVEEERRCWSWFNYLYFWLADCFNINTWQIAGTGLQLGLNWWQCWLTVWIGYTFAGIFVVLNSRFGSAYHLSFPITVRASFGIFFSMWPIINRVVMAIVWYAVQAWLGATPVALMLKSIFGKNLEDRIPNHFGSPNSTTFEFMCFFIFWVVSIPFVLVAPHKIRHLFTVKAALIPFAAFGFLIWALKKSHGKIELGTLNDYSPHGSEFSWIFVRSLMACVANFAALIINAPDFGRFAKNPQASLWPQLVAIPLFFAITCLIGIIVTAAGYHLYGVNYWSPLDVLGQFLETTYTRGTRAGVFLISFVFALAQLGTNISANSLACGADMTALFPRYINIRRGSLFCVAMALCICPWNLMASSSKFTSALGAYAIFLSSIAGVICADYFVVRRGYVKLTHLFLAQKGSFYMFGNKFGANWRAFVAYICGIAPNLPGFIGDVGAPKITVSEGAMRLYYLGYPVGFFISAVIYLILCYFFPVPGTPVTNFLTEKGWFQRWAYVEDFEQDWKNELRRDDLCDDTVSIYDGTEEKIVY
SIO_010081: YIR028W
subclass of: SO_0000673
so part of: YIR028W
location: 408468..410375
location: region:408468-410375:1
so has part: feature:408468-410375:1:exon

NP_012294.3
type: Protein
SIO_000068: ncbiprotein

S000001467
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:408468-410375:1:exon

YIR029W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ALC1
gene: DAL2
locus tag: YIR029W
gene synonym: ALC1
so part of: sequence
location: <410807..>411838
location: region:410807-411838:1
so has part: feature:410807-411838:1:exon
subclass of: SO_0000010

854847
type: Gene
SIO_000068: ncbigene

position:410807:1
position: 410807
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:411838:1
position: 411838
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:410807-411838:1:exon

YIR029W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ALC1
gene: DAL2
locus tag: YIR029W
gene synonym: ALC1
product: allantoicase
transcript id: NM_001179551.1
SIO_010081: YIR029W
subclass of: SO_0000673
so part of: YIR029W
location: <410807..>411838
location: region:410807-411838:1
so has part: feature:410807-411838:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:410807-411838:1:exon

YIR029W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ALC1
gene: DAL2
locus tag: YIR029W
gene synonym: ALC1
EC number: 3.5.3.4
experiment: EXISTENCE:direct assay:GO:0004037 allantoicase activity [PMID:3915539]
experiment: EXISTENCE:mutant phenotype:GO:0000256 allantoin catabolic process [PMID:1916277]
note: Allantoicase; converts allantoate to urea and ureidoglycolate in the second step of allantoin degradation; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation
codon start: 1
product: allantoicase
translation: MKFFSLADEAEFKSIIISKNKAVDVIGSKLGGQVVSFSDEWFASAENLIQPTAPIRDPTRFVHSGAWYDGWETRRHNEMEYDWVIIKMGVAAAHIIGGEIDTAFFNGNHAPFVSIEALYDEGEEGNIVEDDSRWVEIVEKFECGPSQRHLFVRGNGLTKERFTHIKLKMYPDGGIARFRLYGRVVPPELKTKDHIIDLAYVCNGAVALKYSDQHFGSVDNLLLPGRGHDMSDGWETKRSRQPGHTDWAVIQLGRESSFIEKIIVDTAHFRGNFPQFITVEGCLKESESSENTGEGTWVELVGKSKTGPDKEHVYEIRKSIRVSHVKLTIIPDGGVKRIRVWGY
SIO_010081: YIR029W
subclass of: SO_0000673
so part of: YIR029W
location: 410807..411838
location: region:410807-411838:1
so has part: feature:410807-411838:1:exon

NP_012295.1
type: Protein
SIO_000068: ncbiprotein

S000001468
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:410807-411838:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS922; Autonomously Replicating Sequence
so part of: sequence
location: 411935..412011
location: region:411935-412011:1
so has part: feature:411935-412011:1:region

S000118400
type: SGD
SIO_000068: sgd

position:411935:1
position: 411935
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:412011:1
position: 412011
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:411935-412011:1:region

YIR030C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: DCG1
locus tag: YIR030C
so part of: sequence
location: complement(<412036..>412770)
location: region:412036-412770:-1
so has part: feature:412036-412770:-1:exon
subclass of: SO_0000010

854848
type: Gene
SIO_000068: ncbigene

position:412036:-1
position: 412036
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:412770:-1
position: 412770
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:412036-412770:-1:exon

YIR030C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: DCG1
locus tag: YIR030C
product: Dcg1p
transcript id: NM_001179552.1
SIO_010081: YIR030C
subclass of: SO_0000673
so part of: YIR030C
location: complement(<412036..>412770)
location: region:412036-412770:-1
so has part: feature:412036-412770:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:412036-412770:-1:exon

YIR030C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: DCG1
locus tag: YIR030C
experiment: EXISTENCE:expression pattern:GO:0006807 nitrogen compound metabolic process [PMID:1916277]
note: hypothetical protein; expression is sensitive to nitrogen catabolite repression and regulated by Dal80p; contains transmembrane domain
codon start: 1
product: Dcg1p
translation: METRILVVNPNSSKSMTVSLRETIEKTFSMESCKISYFTGPDTSPPQIDGQETSIKSMEACLPLLIDDQESVYYFQKFNGILIACFSDHPLVAKIKDRAAKEKADVSIVGLLDSSINYCNLVGKKFSIITSNKEWIPILNNSVESKFLTGNTVNKNLWKGTVSTDLQVLDLHSPENFQQIAEIIYRENIKKLDSDIVILGCAGFSGLQNKLAKTFQRDGTLFLDTIEIGLQILITMIRFVNSQK
SIO_010081: YIR030C
subclass of: SO_0000673
so part of: YIR030C
location: complement(412036..412770)
location: region:412036-412770:-1
so has part: feature:412036-412770:-1:exon

NP_012296.1
type: Protein
SIO_000068: ncbiprotein

S000001469
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:412036-412770:-1:exon

YIR031C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MLS2
alternative label: MSL2
gene: DAL7
locus tag: YIR031C
gene synonym: MLS2; MSL2
so part of: sequence
location: complement(<413015..>414679)
location: region:413015-414679:-1
so has part: feature:413015-414679:-1:exon
subclass of: SO_0000010

854849
type: Gene
SIO_000068: ncbigene

position:413015:-1
position: 413015
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:414679:-1
position: 414679
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:413015-414679:-1:exon

YIR031C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MLS2
alternative label: MSL2
gene: DAL7
locus tag: YIR031C
gene synonym: MLS2; MSL2
product: malate synthase DAL7
transcript id: NM_001179553.3
SIO_010081: YIR031C
subclass of: SO_0000673
so part of: YIR031C
location: complement(<413015..>414679)
location: region:413015-414679:-1
so has part: feature:413015-414679:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:413015-414679:-1:exon

YIR031C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MLS2
alternative label: MSL2
gene: DAL7
locus tag: YIR031C
gene synonym: MLS2; MSL2
EC number: 2.3.3.9
experiment: EXISTENCE:direct assay:GO:0000256 allantoin catabolic process [PMID:8462696]
experiment: EXISTENCE:direct assay:GO:0004474 malate synthase activity [PMID:8462696]
experiment: EXISTENCE:direct assay:GO:0005777 peroxisome [PMID:27678487]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0004474 malate synthase activity [PMID:23642236]
note: Malate synthase; can accept butyryl-CoA as acyl-CoA donor in addition to traditional substrate acetyl-CoA; recycles glyoxylate generated during allantoin degradation; SWAT-GFP and mCherry fusion proteins localize to the cytosol; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation
codon start: 1
product: malate synthase DAL7
translation: MVKISLDNTALYADIDTTPQFEPSKTTVADILTKDALEFIVLLHRTFNSTRKQLLANRSNLQSKLDSGEYRFDFLPETEQIRNDPTWQGAIPAPGLINRSSEITGPPLRNMLVNALNAEVTTYMTDFEDSSSPTWENMIYGQVNLYDAIRNQIDFKTPRKEYRLKDDISRLPTLIVRPRGWHMVEKHLYIDDEPISASIFDFGLYFYHNAKELVKIGKGPYFYLPKMEHHMEVKLWNDIFCVAQDFIGMPRGTIRATVLIETLPAAFQMEEIIYQIREHSSGLNCGRWDYIFSTIKKLRNLPEHVLPNRDLVTMTSPFMDAYVKRLINTCHRRGVHAMGGMAAQIPIKDDPKANEAAMNKVRNDKIREMKNGHDGSWVAHPALAPICNEVFSNMGTANQIYFVPDVHVTSSDLLNTKIQDAQVTTEGIRVNLDIGLQYMEAWLRGSGCVPINHLMEDAATAEVSRCQLYQWVKHGVVLSDTGDKVTPELTAKILNEETAKLASASPLGEKNKFALAAKYFLPEVTGKIFSDFLTTLLYDEIIKPSAKPVDLSKL
SIO_010081: YIR031C
subclass of: SO_0000673
so part of: YIR031C
location: complement(413015..414679)
location: region:413015-414679:-1
so has part: feature:413015-414679:-1:exon

NP_012297.3
type: Protein
SIO_000068: ncbiprotein

S000001470
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:413015-414679:-1:exon

YIR032C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: DAL3
locus tag: YIR032C
so part of: sequence
location: complement(<415030..>415617)
location: region:415030-415617:-1
so has part: feature:415030-415617:-1:exon
subclass of: SO_0000010

854850
type: Gene
SIO_000068: ncbigene

position:415030:-1
position: 415030
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:415617:-1
position: 415617
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:415030-415617:-1:exon

YIR032C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: DAL3
locus tag: YIR032C
product: ureidoglycolate hydrolase
transcript id: NM_001179554.1
SIO_010081: YIR032C
subclass of: SO_0000673
so part of: YIR032C
location: complement(<415030..>415617)
location: region:415030-415617:-1
so has part: feature:415030-415617:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:415030-415617:-1:exon

YIR032C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: DAL3
locus tag: YIR032C
EC number: 4.3.2.3
experiment: EXISTENCE:curator inference:GO:0000256 allantoin catabolic process [PMID:3915539]
experiment: EXISTENCE:direct assay:GO:0050385 ureidoglycolate lyase activity [PMID:5965980]
experiment: EXISTENCE:mutant phenotype:GO:0050385 ureidoglycolate lyase activity [PMID:3915539]
note: Ureidoglycolate lyase; converts ureidoglycolate to glyoxylate and urea in the third step of allantoin degradation; expression is sensitive to nitrogen catabolite repression; this enzyme is sometimes referred to 'ureidoglycolate hydrolase' but should not be confused with the Arabidopsis thaliana ureidoglycolate hydrolase enzyme which converts ureidoglycolate to glyoxylate, ammonia and carbon dioxide
codon start: 1
product: ureidoglycolate hydrolase
translation: MVTVVAETLTKESFEEYGTIISPDEEISRMQNLEKGANQGTAIKLLQVSQVENKSTSKVPNWNLFRCFPQPHLNRVFTQGSNQAISHSIKVLEKHPCSTQTFVPMGRTSAEVAYLVVVAKEIGNKPDLSTLRAFTCLGNQAVTYGLGTWHAPMIVLGKEEHLDFSVLIYESLDPDRPEKDCVEEHYSDGDVCIII
SIO_010081: YIR032C
subclass of: SO_0000673
so part of: YIR032C
location: complement(415030..415617)
location: region:415030-415617:-1
so has part: feature:415030-415617:-1:exon

NP_012298.1
type: Protein
SIO_000068: ncbiprotein

S000001471
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:415030-415617:-1:exon

YIR033W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MGA2
locus tag: YIR033W
so part of: sequence
location: <416124..>419465
location: region:416124-419465:1
so has part: feature:416124-419465:1:exon
subclass of: SO_0000010

854851
type: Gene
SIO_000068: ncbigene

position:416124:1
position: 416124
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:419465:1
position: 419465
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:416124-419465:1:exon

YIR033W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MGA2
locus tag: YIR033W
product: Mga2p
transcript id: NM_001179555.1
SIO_010081: YIR033W
subclass of: SO_0000673
so part of: YIR033W
location: <416124..>419465
location: region:416124-419465:1
so has part: feature:416124-419465:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:416124-419465:1:exon

YIR033W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MGA2
locus tag: YIR033W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:19061897]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:11007476]
experiment: EXISTENCE:genetic interaction:GO:0030466 silent mating-type cassette heterochromatin formation [PMID:11063674]
experiment: EXISTENCE:genetic interaction:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:9927444]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:11557770|PMID:29627385|PMID:11509659]
experiment: EXISTENCE:mutant phenotype:GO:0048255 mRNA stabilization [PMID:15220333]
note: ER membrane protein involved in regulation of OLE1 transcription; inactive ER form dimerizes and one subunit is then activated by ubiquitin/proteasome-dependent processing followed by nuclear targeting; MGA2 has a paralog, SPT23, that arose from the whole genome duplication
codon start: 1
product: Mga2p
translation: MQQNSEFLTETPGSDPHISQLHANSVMESQLLDDFLLNGSPMYQDDSMAHINIDEGANFQNFIKTDEGDSPNLLSFEGIGNNTHVNQNVSTPLEEEMESNRALKEEEEDEHENKVFNEKNIGNPAHDEIVFGRKETIQSVYINPLDYLKVNAAQLPLDVEVSGLPQVSRVENQLKLKVKITSETPLNQSMLYLPSDSISREKFYLKKNIEDFSEDFKKNLLYINAFVLCAVSNRTTNVCTKCVKREQRRAARRKSGIADNLLWCNNINRRLVVFNNKQVFPIMKTFDNVKEFELTTRLVCYCRHHKANNGFVILFTITDWQNRLLGKFTTTPIMITDRKPANMDTTKFNNTTTSSRRQLTEEESTTEYYSTDNNQLSKDENMPFQYTYQHNPYDNDSQMNNIPLKDKNVPFPYSISQQTDLLQNNNLSLNLSLPNQHIPSPTSMSEEGSESFNYHHRDNDNPVRTISLTNIEQQSQLNQRKRARNNLENDIGKPLFKHSFSNSISATNTMNPALHSMQDFSMKNNNNNLPSINRVIPSQGPINGGIEVTLLGCNFKDGLSVKFGSNLALSTQCWSETTIVTYLPPAAYAGQVFVSITDTNNENNNDDLPQEIEINDNKKAIFTYVDDTDRQLIELALQIVGLKMNGKLEDARNIAKRIVGNDSPDSGTNGNSCSKSTGPSPNQHSMNLNTSVLYSDEVLIQKVIKSLNINSNISICDSLGRTLLHLACLKNYSSLVYTLIKKGARVNDIDSFGLTPLHFACISGDPKIIKMLLNCKVNYSLRSHNGLTAREVFIANHIHSKEIDKKQDNRDNHKFVHNDTYISEVLSLFEEFQNGTKFTDSVETDSNYSISRKYSQSSFNSSLLDNESLNENLFESQSMINPTSMEIQHPTLQLFENSSYSEYDQSDFEEDGDEDLFVTDEVEKPGVACREEQSELLDIGSSANEPEEDNGSTSLWNRVLHRINDDLPKYEDLFPLSWGKDDKLKTTNQDSIVEQSASNIENSENSEEEDYEEEEEFLKKQFNRFFQNKQNFRNDKMLIFFWIPLTLLLLTWFIMYKFGNQDSSINHISELISEYLRIALAKFLLGNERMKTAFRSKLSNLQTTRMLNDLIVS
SIO_010081: YIR033W
subclass of: SO_0000673
so part of: YIR033W
location: 416124..419465
location: region:416124-419465:1
so has part: feature:416124-419465:1:exon

NP_012299.1
type: Protein
SIO_000068: ncbiprotein

S000001472
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:416124-419465:1:exon

YIR034C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: LYS1
locus tag: YIR034C
so part of: sequence
location: complement(<419615..>420736)
location: region:419615-420736:-1
so has part: feature:419615-420736:-1:exon
subclass of: SO_0000010

854852
type: Gene
SIO_000068: ncbigene

position:419615:-1
position: 419615
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:420736:-1
position: 420736
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:419615-420736:-1:exon

YIR034C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: LYS1
locus tag: YIR034C
product: saccharopine dehydrogenase (NAD+, L-lysine-forming)
transcript id: NM_001179556.3
SIO_010081: YIR034C
subclass of: SO_0000673
so part of: YIR034C
location: complement(<419615..>420736)
location: region:419615-420736:-1
so has part: feature:419615-420736:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:419615-420736:-1:exon

YIR034C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: LYS1
locus tag: YIR034C
EC number: 1.5.1.7
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:20844764]
experiment: EXISTENCE:direct assay:GO:0004754 saccharopine dehydrogenase (NAD+, L-lysine-forming) activity [PMID:17002315]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276]
experiment: EXISTENCE:mutant phenotype:GO:0009085 lysine biosynthetic process [PMID:17247984]
experiment: EXISTENCE:mutant phenotype:GO:0016558 protein import into peroxisome matrix [PMID:35563734]
note: Saccharopine dehydrogenase (NAD+, L-lysine-forming); catalyzes the conversion of saccharopine to L-lysine, which is the final step in the lysine biosynthesis pathway; contains mRNA binding activity; required for targeting of Pls1p to the peroxisomal matrix in the absence of lysine
codon start: 1
product: saccharopine dehydrogenase (NAD+, L-lysine-forming)
translation: MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVPAGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYDLEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVTKDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEIPQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNKPTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLFDRHCARVKRSSRL
SIO_010081: YIR034C
subclass of: SO_0000673
so part of: YIR034C
location: complement(419615..420736)
location: region:419615-420736:-1
so has part: feature:419615-420736:-1:exon

NP_012300.3
type: Protein
SIO_000068: ncbiprotein

S000001473
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:419615-420736:-1:exon

YIR035C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: NRE1
locus tag: YIR035C
so part of: sequence
location: complement(<421026..>421790)
location: region:421026-421790:-1
so has part: feature:421026-421790:-1:exon
subclass of: SO_0000010

854853
type: Gene
SIO_000068: ncbigene

position:421026:-1
position: 421026
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:421790:-1
position: 421790
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:421026-421790:-1:exon

YIR035C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: NRE1
locus tag: YIR035C
product: sepiapterin reductase family protein
transcript id: NM_001179557.3
SIO_010081: YIR035C
subclass of: SO_0000673
so part of: YIR035C
location: complement(<421026..>421790)
location: region:421026-421790:-1
so has part: feature:421026-421790:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:421026-421790:-1:exon

YIR035C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: NRE1
locus tag: YIR035C
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095|PMID:11914276]
note: Putative cytoplasmic short-chain dehydrogenase/reductase
codon start: 1
product: sepiapterin reductase family protein
translation: MGKVILVTGVSRGIGKSIVDVLFSLDKDTVVYGVARSEAPLKKLKEKYGDRFFYVVGDITEDSVLKQLVNAAVKGHGKIDSLVANAGVLEPVQNVNEIDVNAWKKLYDINFFSIVSLVGIALPELKKTNGNVVFVSSDACNMYFSSWGAYGSSKAALNHFAMTLANEERQVKAIAVAPGIVDTDMQVNIRENVGPSSMSAEQLKMFRGLKENNQLLDSSVPATVYAKLALHGIPDGVNGQYLSYNDPALADFMP
SIO_010081: YIR035C
subclass of: SO_0000673
so part of: YIR035C
location: complement(421026..421790)
location: region:421026-421790:-1
so has part: feature:421026-421790:-1:exon

NP_012301.3
type: Protein
SIO_000068: ncbiprotein

S000001474
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:421026-421790:-1:exon

YIR036C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: IRC24
locus tag: YIR036C
so part of: sequence
location: complement(<422074..>422865)
location: region:422074-422865:-1
so has part: feature:422074-422865:-1:exon
subclass of: SO_0000010

854854
type: Gene
SIO_000068: ncbigene

position:422074:-1
position: 422074
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:422865:-1
position: 422865
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:422074-422865:-1:exon

YIR036C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: IRC24
locus tag: YIR036C
product: sepiapterin reductase family protein IRC24
transcript id: NM_001179558.3
SIO_010081: YIR036C
subclass of: SO_0000673
so part of: YIR036C
location: complement(<422074..>422865)
location: region:422074-422865:-1
so has part: feature:422074-422865:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:422074-422865:-1:exon

YIR036C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: IRC24
locus tag: YIR036C
EC number: 1.1.1.320
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor [PMID:11796169]
note: Putative benzil reductase;(GFP)-fusion protein localizes to the cytoplasm and is induced by the DNA-damaging agent MMS; sequence similarity with short-chain dehydrogenase/reductases; null mutant has increased spontaneous Rad52p foci
codon start: 1
product: sepiapterin reductase family protein IRC24
translation: MGKVILITGASRGIGLQLVKTVIEEDDECIVYGVARTEAGLQSLQREYGADKFVYRVLDITDRSRMEALVEEIRQKHGKLDGIVANAGMLEPVKSISQSNSEHDIKQWERLFDVNFFSIVSLVALCLPLLKSSPFVGNIVFVSSGASVKPYNGWSAYGCSKAALNHFAMDIASEEPSDKVRAVCIAPGVVDTQMQKDIRETLGPQGMTPKALERFTQLYKTSSLLDPKVPAAVLAQLVLKGIPDSLNGQYLRYNDERLGPVQG
SIO_010081: YIR036C
subclass of: SO_0000673
so part of: YIR036C
location: complement(422074..422865)
location: region:422074-422865:-1
so has part: feature:422074-422865:-1:exon

NP_012302.3
type: Protein
SIO_000068: ncbiprotein

S000001475
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:422074-422865:-1:exon

YIR037W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: GPX3
alternative label: ORP1
gene: HYR1
locus tag: YIR037W
gene synonym: GPX3; ORP1
so part of: sequence
location: <423128..>423619
location: region:423128-423619:1
so has part: feature:423128-423619:1:exon
subclass of: SO_0000010

854855
type: Gene
SIO_000068: ncbigene

position:423128:1
position: 423128
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:423619:1
position: 423619
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:423128-423619:1:exon

YIR037W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: GPX3
alternative label: ORP1
gene: HYR1
locus tag: YIR037W
gene synonym: GPX3; ORP1
product: peroxiredoxin HYR1
transcript id: NM_001179559.1
SIO_010081: YIR037W
subclass of: SO_0000673
so part of: YIR037W
location: <423128..>423619
location: region:423128-423619:1
so has part: feature:423128-423619:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:423128-423619:1:exon

YIR037W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: GPX3
alternative label: ORP1
gene: HYR1
locus tag: YIR037W
gene synonym: GPX3; ORP1
EC number: 1.11.1.24
experiment: EXISTENCE:direct assay:GO:0004602 glutathione peroxidase activity [PMID:19755417]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005758 mitochondrial intermembrane space [PMID:22984289]
experiment: EXISTENCE:direct assay:GO:0005782 peroxisomal matrix [PMID:22659048]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity [PMID:11445588]
experiment: EXISTENCE:mutant phenotype:GO:0004602 glutathione peroxidase activity [PMID:10480913]
experiment: EXISTENCE:mutant phenotype:GO:0034599 cellular response to oxidative stress [PMID:11445588]
experiment: EXISTENCE:mutant phenotype:GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity [PMID:11445588]
note: Glutathione peroxidase; functions as hydroperoxide receptor to sense intracellular hydroperoxide levels and transduce redox signal to Yap1p transcription factor; glutathione peroxidase activity is neuroprotective in models of Huntington's disease; HYR1 has a paralog, GPX1, that arose from the whole genome duplication
codon start: 1
product: peroxiredoxin HYR1
translation: MSEFYKLAPVDKKGQPFPFDQLKGKVVLIVNVASKCGFTPQYKELEALYKRYKDEGFTIIGFPCNQFGHQEPGSDEEIAQFCQLNYGVTFPIMKKIDVNGGNEDPVYKFLKSQKSGMLGLRGIKWNFEKFLVDKKGKVYERYSSLTKPSSLSETIEELLKEVE
SIO_010081: YIR037W
subclass of: SO_0000673
so part of: YIR037W
location: 423128..423619
location: region:423128-423619:1
so has part: feature:423128-423619:1:exon

NP_012303.1
type: Protein
SIO_000068: ncbiprotein

S000001476
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:423128-423619:1:exon

YIR038C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GTT1
locus tag: YIR038C
so part of: sequence
location: complement(<423809..>424513)
location: region:423809-424513:-1
so has part: feature:423809-424513:-1:exon
subclass of: SO_0000010

854856
type: Gene
SIO_000068: ncbigene

position:423809:-1
position: 423809
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:424513:-1
position: 424513
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:423809-424513:-1:exon

YIR038C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GTT1
locus tag: YIR038C
product: bifunctional glutathione transferase/peroxidase
transcript id: NM_001179560.1
SIO_010081: YIR038C
subclass of: SO_0000673
so part of: YIR038C
location: complement(<423809..>424513)
location: region:423809-424513:-1
so has part: feature:423809-424513:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:423809-424513:-1:exon

YIR038C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GTT1
locus tag: YIR038C
EC number: 2.5.1.18
experiment: EXISTENCE:direct assay:GO:0004364 glutathione transferase activity [PMID:9792709]
experiment: EXISTENCE:direct assay:GO:0004602 glutathione peroxidase activity [PMID:16709151]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005741 mitochondrial outer membrane [PMID:16407407]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:9792709|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:16622836]
experiment: EXISTENCE:direct assay:GO:0006749 glutathione metabolic process [PMID:9792709]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0010731 protein glutathionylation [PMID:27708136]
note: ER associated glutathione S-transferase; capable of homodimerization; glutathione transferase for Yvc1p vacuolar cation channel; expression induced during the diauxic shift and throughout stationary phase; functional overlap with Gtt2p, Grx1p, and Grx2p
codon start: 1
product: bifunctional glutathione transferase/peroxidase
translation: MSLPIIKVHWLDHSRAFRLLWLLDHLNLEYEIVPYKRDANFRAPPELKKIHPLGRSPLLEVQDRETGKKKILAESGFIFQYVLQHFDHSHVLMSEDADIADQINYYLFYVEGSLQPPLMIEFILSKVKDSGMPFPISYLARKVADKISQAYSSGEVKNQFDFVEGEISKNNGYLVDGKLSGADILMSFPLQMAFERKFAAPEDYPAISKWLKTITSEESYAASKEKARALGSNF
SIO_010081: YIR038C
subclass of: SO_0000673
so part of: YIR038C
location: complement(423809..424513)
location: region:423809-424513:-1
so has part: feature:423809-424513:-1:exon

NP_012304.1
type: Protein
SIO_000068: ncbiprotein

S000001477
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:423809-424513:-1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(426201..426425)
location: region:426201-426425:-1
so has part: feature:426201-426425:-1:region

S000007021
type: SGD
SIO_000068: sgd

position:426201:-1
position: 426201
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:426425:-1
position: 426425
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:426201-426425:-1:region

YIR039C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: YPS6
locus tag: YIR039C
so part of: sequence
location: complement(<430498..>432111)
location: region:430498-432111:-1
so has part: feature:430498-432111:-1:exon
subclass of: SO_0000010

854857
type: Gene
SIO_000068: ncbigene

position:430498:-1
position: 430498
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:432111:-1
position: 432111
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:430498-432111:-1:exon

YIR039C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: YPS6
locus tag: YIR039C
product: aspartyl protease
transcript id: NM_001179561.3
SIO_010081: YIR039C
subclass of: SO_0000673
so part of: YIR039C
location: complement(<430498..>432111)
location: region:430498-432111:-1
so has part: feature:430498-432111:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:430498-432111:-1:exon

YIR039C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: YPS6
locus tag: YIR039C
experiment: EXISTENCE:direct assay:GO:0009277 fungal-type cell wall [PMID:10383953]
experiment: EXISTENCE:genetic interaction:GO:0031505 fungal-type cell wall organization [PMID:16087741]
note: Putative GPI-anchored aspartic protease; member of the yapsin family of proteases involved in cell wall growth and maintenance
codon start: 1
product: aspartyl protease
translation: MQLISILSLLSSLMCSLTVLGSSASSYVKFPVQKLADIINICTQDVSTVFKRNEVLNTTVINGIGVYVVKMEIGTPPQTLYLQLDTGSSDMIVNNADIAYCKSMSDGSDYASTDNYELTATFNGLPSTTISSEAYNTLCSYWGTFDASNSSTFENNATFFNNTYGDGTYYAGTYGTDVVSFENITLNDFTFGVSNDTIGNPSGILGISLPIAEFTDGIEYALALNRTPFIYDNFPMELKNQGKINKIAYSLFLNGPDAHFGSILFGAVDKSKYTGQLYTLPMLQAFNTLGSNPGMIITAQSVAILDSESGNKTVSDIQFPVMLDSGTTFSYLPTEIAEAIGKSFDGEYSSDDQGYIFDCSKVNDTLLSVDFGGFNISANISNFVTSAKDRCVLNVKQSESTYMLGDAFLVDAYVVYDLENYEISIAQASFNNQEEDIEVISDTVPGATPAPGYFSTWVYKPGSPIGTGDFINVSWTSYSEFSQYKSLLATAAQSDDASSFSSSGGSSESTTKKQNAGYKYRSSFSFSLLSFISYFLL
SIO_010081: YIR039C
subclass of: SO_0000673
so part of: YIR039C
location: complement(430498..432111)
location: region:430498-432111:-1
so has part: feature:430498-432111:-1:exon

NP_012305.3
type: Protein
SIO_000068: ncbiprotein

S000001478
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:430498-432111:-1:exon

YIR041W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PAU15
locus tag: YIR041W
so part of: sequence
location: <433929..>434303
location: region:433929-434303:1
so has part: feature:433929-434303:1:exon
subclass of: SO_0000010

854859
type: Gene
SIO_000068: ncbigene

position:433929:1
position: 433929
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:434303:1
position: 434303
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:433929-434303:1:exon

YIR041W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PAU15
locus tag: YIR041W
product: seripauperin PAU15
transcript id: NM_001179563.1
SIO_010081: YIR041W
subclass of: SO_0000673
so part of: YIR041W
location: <433929..>434303
location: region:433929-434303:1
so has part: feature:433929-434303:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:433929-434303:1:exon

YIR041W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PAU15
locus tag: YIR041W
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
note: hypothetical protein; member of the seripauperin multigene family encoded mainly in subtelomeric regions; SWAT-GFP and mCherry fusion proteins localize to the vacuole
codon start: 1
product: seripauperin PAU15
translation: MVKLTSIAAGVAAIAAGVAAAPATTTLSPSDERVNLVELGVYVSDIRAHLAQYYLFQAAHPSETYPVEIAEAVFNYGDFTTMLTGIPAEQVTRVITGVPWYSTRLRPAISSALSKDGIYTAIPK
SIO_010081: YIR041W
subclass of: SO_0000673
so part of: YIR041W
location: 433929..434303
location: region:433929-434303:1
so has part: feature:433929-434303:1:exon

NP_012307.1
type: Protein
SIO_000068: ncbiprotein

S000001480
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:433929-434303:1:exon

YIR042C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YIR042C
so part of: sequence
location: complement(<435273..>435983)
location: region:435273-435983:-1
so has part: feature:435273-435983:-1:exon
subclass of: SO_0000010

854860
type: Gene
SIO_000068: ncbigene

position:435273:-1
position: 435273
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:435983:-1
position: 435983
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:435273-435983:-1:exon

YIR042C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YIR042C
product: uncharacterized protein
transcript id: NM_001179564.1
SIO_010081: YIR042C
subclass of: SO_0000673
so part of: YIR042C
location: complement(<435273..>435983)
location: region:435273-435983:-1
so has part: feature:435273-435983:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:435273-435983:-1:exon

YIR042C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YIR042C
note: hypothetical protein; YIR042C is a non-essential gene
codon start: 1
product: uncharacterized protein
translation: MANLNIFGQEVGADVEGWTTRAFPEKVVLKGNTCRLEPLDRERHGSELFSAYSEAGQKLWTYLPAGPFTNLEEYLEFIKELNETKDTVPFAIINKETERAVGTLCLIRIDEANGSLEVGYVVFSPELQKTIIATEAQFLLMKYVFDDLQYRRYEWKCDSLNGPSRRAAMRLGFKYEGTFRQVVVYKGRTRDTQWFSIIDKEWLRIRKTFEEWLDKTNFENGKQKRGIAAIRESLSN
SIO_010081: YIR042C
subclass of: SO_0000673
so part of: YIR042C
location: complement(435273..435983)
location: region:435273-435983:-1
so has part: feature:435273-435983:-1:exon

NP_012308.1
type: Protein
SIO_000068: ncbiprotein

S000001481
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:435273-435983:-1:exon

YIR043C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YIR044C
locus tag: YIR043C
gene synonym: YIR044C
pseudo: true
so part of: sequence
location: complement(437043..438179)
location: region:437043-438179:-1
so has part: feature:437043-438179:-1:exon

854861
type: Gene
SIO_000068: ncbigene

position:437043:-1
position: 437043
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:438179:-1
position: 438179
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:437043-438179:-1:exon

YIR043C
type: Miscellaneous Feature
subclass of: SO_0000001
RO_0002162: 559292
alternative label: YIR044C
locus tag: YIR043C
gene synonym: YIR044C
note: Blocked reading frame; may encode a non-functional member of the conserved, often subtelomerically-encoded Cos protein family
pseudo: true
SIO_010081: YIR043C
subclass of: SO_0000673
so part of: YIR043C
location: complement(437043..438179)
location: region:437043-438179:-1
so has part: feature:437043-438179:-1:exon

S000001482
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:437043-438179:-1:exon

telomere
type: Telomere
subclass of: SO_0000624
RO_0002162: 559292
note: TEL09R; Telomeric region on the right arm of Chromosome IX; composed of an X element core sequence, X element combinatorial repeats, and a short terminal stretch of telomeric repeats
so part of: sequence
location: 439068..439888
location: region:439068-439888:1
so has part: feature:439068-439888:1:region

S000028970
type: SGD
SIO_000068: sgd

position:439068:1
position: 439068
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:439068-439888:1:region