Saccharomyces cerevisiae S288C chromosome VI, complete sequence.
type: Entry
definition: Saccharomyces cerevisiae S288C chromosome VI, complete sequence.
sequence version: NC_001138.5
sequence date: 2023-01-18
sequence: sequence
division: CON
label: NC_001138.5
type: RefSeq
SIO_000068: refseq
dblink: PRJNA128
keyword: RefSeq
source: Saccharomyces cerevisiae S288C
organism: Saccharomyces cerevisiae S288C
taxonomy: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
reference: 1
references: 34897464
reference: 2
references: 8849441
reference: 3
references: 7670463
reference: 4
reference: 5
reference: 6
reference: 7
reference: 8
comment: REVIEWED REFSEQ: This record has been curated by SGD. The reference\nsequence is identical to BK006940.\n\nOn Apr 26, 2011 this sequence version replaced NC_001138.4.\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: SGD\nAnnotation Status :: Full Annotation\nAnnotation Version :: R64-3-1\nURL :: http://www.yeastgenome.org/\n##Genome-Annotation-Data-END##\nCOMPLETENESS: full length.

sequence
subclass of: SO_0000340
sequence length: 270161
topology: linear
so has quality: SO_0000987
location: 1..270161
location: region:1-270161:1
RO_0002162: 559292

NC_001138
type: RefSeq
SIO_000068: refseq

PRJNA128
type: BioProject
SIO_000068: bioproject

1
title: New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources
author: Engel, S.R.
author: Wong, E.D.
author: Nash, R.S.
author: Aleksander, S.
author: Alexander, M.
author: Douglass, E.
author: Karra, K.
author: Miyasato, S.R.
author: Simison, M.
author: Skrzypek, M.S.
author: Weng, S.
author: Cherry, J.M.
journal: Genetics 220 (4) (2022)
pubmed: 34897464

34897464
type: PubMed
SIO_000068: pubmed

2
title: Life with 6000 genes
author: Goffeau, A.
author: Barrell, B.G.
author: Bussey, H.
author: Davis, R.W.
author: Dujon, B.
author: Feldmann, H.
author: Galibert, F.
author: Hoheisel, J.D.
author: Jacq, C.
author: Johnston, M.
author: Louis, E.J.
author: Mewes, H.W.
author: Murakami, Y.
author: Philippsen, P.
author: Tettelin, H.
author: Oliver, S.G.
journal: Science 274 (5287), 546 (1996)
pubmed: 8849441

8849441
type: PubMed
SIO_000068: pubmed

3
title: Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae
author: Murakami, Y.
author: Naitou, M.
author: Hagiwara, H.
author: Shibata, T.
author: Ozawa, M.
author: Sasanuma, S.
author: Sasanuma, M.
author: Tsuchiya, Y.
author: Soeda, E.
author: Yokoyama, K. et al.
journal: Nat. Genet.
volume: 10
issue: 3
pages: 261-268
year: 1995
pubmed: 7670463

7670463
type: PubMed
SIO_000068: pubmed

4
title: Direct Submission
journal: Submitted (13-JAN-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA

5
title: Direct Submission
journal: Submitted (16-JAN-2015) Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA
comments: Protein update by submitter

6
title: Direct Submission
journal: Submitted (04-MAY-2012) Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA
comments: Protein update by submitter

7
title: Direct Submission
journal: Submitted (31-MAR-2011) Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA
comments: Sequence update by submitter

8
title: Direct Submission
journal: Submitted (11-DEC-2009) Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA

position:1:1
position: 1
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:270161:1
position: 270161
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

feature:1-270161:1:source
so part of: sequence
organism: Saccharomyces cerevisiae S288C
mol type: genomic DNA
strain: S288C
chromosome: VI

559292
type: Taxonomy
SIO_000068: taxonomy

telomere
type: Telomere
subclass of: SO_0000624
RO_0002162: 559292
note: TEL06L; Telomeric region on the left arm of Chromosome VI; composed of an X element core sequence, X element combinatorial repeats, a stretch of telomeric repeats, and a short Y' element
so part of: sequence
location: complement(1..5530)
location: region:1-5530:-1
so has part: feature:1-5530:-1:region

S000028882
type: SGD
SIO_000068: sgd

position:1:-1
position: 1
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:5530:-1
position: 5530
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:1-5530:-1:region

YFL068W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YFL068W
so part of: sequence
location: <53..>535
location: region:53-535:1
so has part: feature:53-535:1:exon
subclass of: SO_0000010

850476
type: Gene
SIO_000068: ncbigene

position:53:1
position: 53
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:535:1
position: 535
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:53-535:1:exon

YFL068W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YFL068W
product: uncharacterized protein
transcript id: NM_001179899.1
SIO_010081: YFL068W
subclass of: SO_0000673
so part of: YFL068W
location: <53..>535
location: region:53-535:1
so has part: feature:53-535:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:53-535:1:exon

YFL068W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YFL068W
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
note: hypothetical protein; SWAT-GFP and mCherry fusion proteins localize to the cytosol
codon start: 1
product: uncharacterized protein
translation: MMPAKLQLDVLRTLQSSARHGTQTLKNSNFLERFHKDRIVFCLPFFPALFLVPVQKVLQHLCLRFTQVAPYFIIQLFDLPSRHAENLAPLLASCRIQYTNCFSSSSNGQVPSIISLYLRVDLSPFYAKKFQIPYRVPMIWLDVFQVFFVFLVISQHSLHS
SIO_010081: YFL068W
subclass of: SO_0000673
so part of: YFL068W
location: 53..535
location: region:53-535:1
so has part: feature:53-535:1:exon

NP_116587.1
type: Protein
SIO_000068: ncbiprotein

S000001826
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:53-535:1:exon

YFL067W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YFL067W
so part of: sequence
location: <836..>1363
location: region:836-1363:1
so has part: feature:836-1363:1:exon
subclass of: SO_0000010

850477
type: Gene
SIO_000068: ncbigene

position:836:1
position: 836
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:1363:1
position: 1363
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:836-1363:1:exon

YFL067W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YFL067W
product: uncharacterized protein
transcript id: NM_001179900.1
SIO_010081: YFL067W
subclass of: SO_0000673
so part of: YFL067W
location: <836..>1363
location: region:836-1363:1
so has part: feature:836-1363:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:836-1363:1:exon

YFL067W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YFL067W
note: hypothetical protein; down-regulated at low calcium levels; mCherry fusion protein localizes to the vacuole
codon start: 1
product: uncharacterized protein
translation: MESIILSIAIFIGVLLGTSVGAGSGSSISPDVDAGSGSRTSPDVDAGSGSRISAGVGTFSGSSTSPDVDAGSGSSTSPDVGAGSGSSISAGVGSRIGTGIGSRIGTGIGTGIGSRISTSIGSRISPDVGTSSGNRISTGVSTGISTTMNARVAVLITAAILSAPVTAIALLEARR
SIO_010081: YFL067W
subclass of: SO_0000673
so part of: YFL067W
location: 836..1363
location: region:836-1363:1
so has part: feature:836-1363:1:exon

NP_116588.1
type: Protein
SIO_000068: ncbiprotein

S000001827
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:836-1363:1:exon

YFL066C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YFL066C
so part of: sequence
location: complement(<1437..>2615)
location: region:1437-2615:-1
so has part: feature:1437-2615:-1:exon
subclass of: SO_0000010

850478
type: Gene
SIO_000068: ncbigene

position:1437:-1
position: 1437
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:2615:-1
position: 2615
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:1437-2615:-1:exon

YFL066C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YFL066C
product: Y' element ATP-dependent helicase
transcript id: NM_001179901.1
SIO_010081: YFL066C
subclass of: SO_0000673
so part of: YFL066C
location: complement(<1437..>2615)
location: region:1437-2615:-1
so has part: feature:1437-2615:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:1437-2615:-1:exon

YFL066C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YFL066C
EC number: 3.6.4.12
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:26928762]
note: Helicase-like protein encoded within the telomeric Y' element; induced by treatment with 8-methoxypsoralen and UVA irradiation; SWAT-GFP and mCherry fusion proteins localize to the nucleus
codon start: 1
product: Y' element ATP-dependent helicase
translation: MADTPSVAVQAPPGYGKTELFHLPLIALASKGDVKYVSFLFVPYTVLLANCMIRLGRRGCLNVAPVRNFIEEGYDGVTDLYVGIYDDLASTNFTDRIAAWENIVECTFRTNNVKLGYLIVDEFHNFETEVYRQSQFGGITNLDFDAFEKAIFLSGTAPEAVADAALQRIGLTGLAKKSMDINELKRSEDLSRGLSSYPTRMFNLIKEKSEVPLGHVHKIWKKVESQPEEALKLLLALFEIEPESKAIVVASTTNEVEELACSWRKYFRVVWIHGKLGAAEKVSRTKEFVTDGSMQVLIGTKLVTEGIDIKQLMMVIMLDNRLNIIELIQGVGRLRDGGLCYLLSRKNSWAARNRKGELPPIKEGCITEQVREFYGLESKKGKKGQHVGCCVC
SIO_010081: YFL066C
subclass of: SO_0000673
so part of: YFL066C
location: complement(1437..2615)
location: region:1437-2615:-1
so has part: feature:1437-2615:-1:exon

NP_116589.1
type: Protein
SIO_000068: ncbiprotein

S000001828
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:1437-2615:-1:exon

YFL065C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YFL065C
so part of: sequence
location: complement(<3030..>3338)
location: region:3030-3338:-1
so has part: feature:3030-3338:-1:exon
subclass of: SO_0000010

850479
type: Gene
SIO_000068: ncbigene

position:3030:-1
position: 3030
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:3338:-1
position: 3338
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:3030-3338:-1:exon

YFL065C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YFL065C
product: uncharacterized protein
transcript id: NM_001179902.1
SIO_010081: YFL065C
subclass of: SO_0000673
so part of: YFL065C
location: complement(<3030..>3338)
location: region:3030-3338:-1
so has part: feature:3030-3338:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:3030-3338:-1:exon

YFL065C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YFL065C
note: hypothetical protein; induced by treatment with 8-methoxypsoralen and UVA irradiation
codon start: 1
product: uncharacterized protein
translation: MRTFTDFVSGAPIVRSLQKSTIRKYGYNLAPHMFLLLHVDELSIFSAYQASLPGEKKVDTERLKRDLCPRKPIEIKYFSQICNDMMNKKDRLGDVLRVCCPS
SIO_010081: YFL065C
subclass of: SO_0000673
so part of: YFL065C
location: complement(3030..3338)
location: region:3030-3338:-1
so has part: feature:3030-3338:-1:exon

NP_116590.1
type: Protein
SIO_000068: ncbiprotein

S000001829
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:3030-3338:-1:exon

YFL064C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YFL064C
so part of: sequence
location: complement(<3322..>3846)
location: region:3322-3846:-1
so has part: feature:3322-3846:-1:exon
subclass of: SO_0000010

850480
type: Gene
SIO_000068: ncbigene

position:3322:-1
position: 3322
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:3846:-1
position: 3846
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:3322-3846:-1:exon

YFL064C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YFL064C
product: uncharacterized protein
transcript id: NM_001179903.1
SIO_010081: YFL064C
subclass of: SO_0000673
so part of: YFL064C
location: complement(<3322..>3846)
location: region:3322-3846:-1
so has part: feature:3322-3846:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:3322-3846:-1:exon

YFL064C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YFL064C
codon start: 1
product: uncharacterized protein
translation: MKVSDRRKFEKANFDEFESALNNKNDLVHCPSITLFESIPTEVRSFYEDEKSGLIKVVKFRTGAMNRKRSFEKIVISVMVGKNVQKFLTFVEDEPDFQGGPIPSKYLIPKKINLMVYTLFQVHTLKFNRKDYDTLSLFYLNRGYYNELSFPCPGTLSRNSECQAERQLYDAYFH
SIO_010081: YFL064C
subclass of: SO_0000673
so part of: YFL064C
location: complement(3322..3846)
location: region:3322-3846:-1
so has part: feature:3322-3846:-1:exon

NP_116591.1
type: Protein
SIO_000068: ncbiprotein

S000001830
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:3322-3846:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS600; Subtelomeric Autonomously Replicating Sequence; originally published as ARS120
so part of: sequence
location: 5426..5529
location: region:5426-5529:1
so has part: feature:5426-5529:1:region

S000029653
type: SGD
SIO_000068: sgd

position:5426:1
position: 5426
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:5529:1
position: 5529
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:5426-5529:1:region

YFL062W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: COS4
locus tag: YFL062W
so part of: sequence
location: <6426..>7565
location: region:6426-7565:1
so has part: feature:6426-7565:1:exon
subclass of: SO_0000010

850482
type: Gene
SIO_000068: ncbigene

position:6426:1
position: 6426
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:7565:1
position: 7565
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:6426-7565:1:exon

YFL062W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: COS4
locus tag: YFL062W
product: Cos4p
transcript id: NM_001179905.1
SIO_010081: YFL062W
subclass of: SO_0000673
so part of: YFL062W
location: <6426..>7565
location: region:6426-7565:1
so has part: feature:6426-7565:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:6426-7565:1:exon

YFL062W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: COS4
locus tag: YFL062W
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:14562095|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005768 endosome [PMID:25942624]
note: Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins
codon start: 1
product: Cos4p
translation: MKENELKNEKSVDVLSFKQLESQKIVLPQDLFRSSFTWFCYEIYKSLAFRIWMLLWLPLSVWWKLSNNWIYPLMVSLLVLFWGPVFVLVIFRLSRKRSLSKQLTQFCKEITKSTPSSDPHDWEVVAANLNSYLYENKAWNIRYFFFNAMGCQEAFRTTLLEPFSLKKDEAAKVKSFKDSVPYIEEALGVYFREVEKQWKLFNSEKSWSPVGLEDAKLPKEAYRFKLTWFLKRISNIFMLIPFLNFLCCIYVSRGMCLLLRTLYLGWILFMLVQGFQNIRVLIMSMEHKMQFLSTIINEQESGANGWDEIARKMNRYLFEKKVWKNEEFFFDGIDCEWFFSHFFYRVLSAKKSMRALSLNVELWPYIKEAQLSCSEESLA
SIO_010081: YFL062W
subclass of: SO_0000673
so part of: YFL062W
location: 6426..7565
location: region:6426-7565:1
so has part: feature:6426-7565:1:exon

NP_116593.1
type: Protein
SIO_000068: ncbiprotein

S000001832
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:6426-7565:1:exon

YFL061W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: DDI2
gene: DDI3
locus tag: YFL061W
gene synonym: DDI2
so part of: sequence
location: <9545..>10222
location: region:9545-10222:1
so has part: feature:9545-10222:1:exon
subclass of: SO_0000010

850483
type: Gene
SIO_000068: ncbigene

position:9545:1
position: 9545
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:10222:1
position: 10222
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:9545-10222:1:exon

YFL061W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: DDI2
gene: DDI3
locus tag: YFL061W
gene synonym: DDI2
product: cyanamide hydratase
transcript id: NM_001179906.1
SIO_010081: YFL061W
subclass of: SO_0000673
so part of: YFL061W
location: <9545..>10222
location: region:9545-10222:1
so has part: feature:9545-10222:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:9545-10222:1:exon

YFL061W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: DDI2
gene: DDI3
locus tag: YFL061W
gene synonym: DDI2
EC number: 4.2.1.69
experiment: EXISTENCE:direct assay:GO:0018820 cyanamide hydratase activity [PMID:25847245]
experiment: EXISTENCE:mutant phenotype:GO:0018890 cyanamide metabolic process [PMID:25847245]
note: Cyanamide hydratase that detoxifies cyanamide; member of the HD domain metalloprotein superfamily; expression is induced over 100-fold by cyanamide and by SN2-type DNA alkylating agents such as MMS and DMA; induction decreased in rad6 and rad18 mutants; gene and protein are identical to DDI2 and Ddi2p
codon start: 1
product: cyanamide hydratase
translation: MSQYGFVRVPREVEKAIPVVNAPRPRAVVPPPNSETARLVREYAAKELTAPVLNHSLRVFQYSVAIIRDQFPAWDLDQEVLYVTCLLHDIATTDKNMRATKMSFEYYGGILSRELVFNATGGNQDYADAVTEAIIRHQDLTGTGYITTLGLILQIATTLDNVGSNTDLIHIDTVSAINEQFPRLHWLSCFATVVDTENSRKPWGHTSSLGDDFSKKVICNTFGYN
SIO_010081: YFL061W
subclass of: SO_0000673
so part of: YFL061W
location: 9545..10222
location: region:9545-10222:1
so has part: feature:9545-10222:1:exon

NP_116594.1
type: Protein
SIO_000068: ncbiprotein

S000001833
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:9545-10222:1:exon

YFL060C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SNO3
locus tag: YFL060C
so part of: sequence
location: complement(<10301..>10969)
location: region:10301-10969:-1
so has part: feature:10301-10969:-1:exon
subclass of: SO_0000010

850484
type: Gene
SIO_000068: ncbigene

position:10301:-1
position: 10301
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:10969:-1
position: 10969
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:10301-10969:-1:exon

YFL060C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SNO3
locus tag: YFL060C
product: putative pyridoxal 5'-phosphate synthase
transcript id: NM_001179907.1
SIO_010081: YFL060C
subclass of: SO_0000673
so part of: YFL060C
location: complement(<10301..>10969)
location: region:10301-10969:-1
so has part: feature:10301-10969:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:10301-10969:-1:exon

YFL060C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SNO3
locus tag: YFL060C
EC number: 3.5.1.2
EC number: 4.3.3.6
experiment: EXISTENCE:direct assay:GO:0008614 pyridoxine metabolic process [PMID:9791124]
note: hypothetical protein; nearly identical to Sno2p; expression is induced before the diauxic shift and also in the absence of thiamin
codon start: 1
product: putative pyridoxal 5'-phosphate synthase
translation: MTVVIGVLALQGAFIEHVRHVEKCIVENRDFYEKKLSVMTVKDKNQLAQCDALIIPGGESTAMSLIAERTGFYDDLYAFVHNPSKVTWGTCAGLIYISQQLSNEAKLVKTLNLLKVKVKRNAFGRQAQSSTRICDFSNFIPHCNDFPATFIRAPVIEEVLDPEHVQVLYKLDGKDNGGQELIVAAKQKNNILATSFHPELAENDIRFHDWFIREFVLKNYSK
SIO_010081: YFL060C
subclass of: SO_0000673
so part of: YFL060C
location: complement(10301..10969)
location: region:10301-10969:-1
so has part: feature:10301-10969:-1:exon

NP_116595.1
type: Protein
SIO_000068: ncbiprotein

S000001834
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:10301-10969:-1:exon

YFL059W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SNZ3
locus tag: YFL059W
so part of: sequence
location: <11363..>12259
location: region:11363-12259:1
so has part: feature:11363-12259:1:exon
subclass of: SO_0000010

850485
type: Gene
SIO_000068: ncbigene

position:11363:1
position: 11363
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:12259:1
position: 12259
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:11363-12259:1:exon

YFL059W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SNZ3
locus tag: YFL059W
product: pyridoxine biosynthesis protein SNZ3
transcript id: NM_001179908.1
SIO_010081: YFL059W
subclass of: SO_0000673
so part of: YFL059W
location: <11363..>12259
location: region:11363-12259:1
so has part: feature:11363-12259:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:11363-12259:1:exon

YFL059W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SNZ3
locus tag: YFL059W
EC number: 4.3.3.6
experiment: EXISTENCE:direct assay:GO:0036381 pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity [PMID:30498136]
experiment: EXISTENCE:genetic interaction:GO:0008615 pyridoxine biosynthetic process [PMID:30498136]
experiment: EXISTENCE:genetic interaction:GO:0009228 thiamine biosynthetic process [PMID:30498136]
note: Pyridoxal-5'-phosphate synthase; involved in thiamine and pyridoxine biosynthesis; member of a stationary phase-induced gene family where transcriptional induction precedes the diauxic shift; induced in the absence of thiamine in a Thi2/3p-dependent manner and repressed in its presence; forms a co-regulated gene pair with SNO3; paralog of SNZ1 and SNZ2
codon start: 1
product: pyridoxine biosynthesis protein SNZ3
translation: MSEFKVKTGLAQMLKGGVIMDVVTPEQAIIAERAGACAVMALERIPADMRKSGQVCRMSDPRMIKEIMEAVSIPVMAKVRIGHFVEAQILEELQVDYIDESEVLTPADWTHHIEKHNFKVPFVCGAKDLGEALRRINEGAAMIRTKGEAGTGDVSEAVKHITKIKAEIQQYKENLKTESDFAAKATELRVPVDLLKTTLSEGKLPVVNFAAGGVATPADAALLMQLGCEGVFVGSGIFKSSDPEKLACAIVEATTHYDNPAKLLQVSSDLGDLMGGISIQSINEAGGKNGARLSEIGW
SIO_010081: YFL059W
subclass of: SO_0000673
so part of: YFL059W
location: 11363..12259
location: region:11363-12259:1
so has part: feature:11363-12259:1:exon

NP_116596.1
type: Protein
SIO_000068: ncbiprotein

S000001835
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:11363-12259:1:exon

YFL058W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: THI5
locus tag: YFL058W
so part of: sequence
location: <12929..>13951
location: region:12929-13951:1
so has part: feature:12929-13951:1:exon
subclass of: SO_0000010

850486
type: Gene
SIO_000068: ncbigene

position:12929:1
position: 12929
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:13951:1
position: 13951
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:12929-13951:1:exon

YFL058W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: THI5
locus tag: YFL058W
product: 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase
transcript id: NM_001179909.1
SIO_010081: YFL058W
subclass of: SO_0000673
so part of: YFL058W
location: <12929..>13951
location: region:12929-13951:1
so has part: feature:12929-13951:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:12929-13951:1:exon

YFL058W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: THI5
locus tag: YFL058W
experiment: EXISTENCE:genetic interaction:GO:0009228 thiamine biosynthetic process [PMID:12777485]
note: Protein involved in synthesis of the thiamine precursor HMP; member of a subtelomeric gene family including THI5, THI11, THI12, and THI13; hydroxymethylpyrimidine is also known as HMP
codon start: 1
product: 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase
translation: MSTDKITFLLNWQPTPYHIPIFLAQTKGYFKEQGLDMAILEPTNPSDVTELIGSGKVDMGLKAMIHTLAAKARGFPVTSVASLLDEPFTGVLYLKGSGITEDFQSLKGKKIGYVGEFGKIQIDELTKHYGMKPEDYTAVRCGMNVAKYIIEGKIDAGIGIECMQQVELEEYLAKQGRPASDAKMLRIDKLACLGCCCFCTVLYICNDEFLKKNPEKVRKFLKAIKKATDYVLADPVKAWKEYIDFKPQLNNDLSYKQYQRCYAYFSSSLYNVHRDWKKVTGYGKRLAILPPDYVSNYTNEYLSWPEPEEVSDPLEAQRLMAIHQEKCRQEGTFKRLALPA
SIO_010081: YFL058W
subclass of: SO_0000673
so part of: YFL058W
location: 12929..13951
location: region:12929-13951:1
so has part: feature:12929-13951:1:exon

NP_116597.1
type: Protein
SIO_000068: ncbiprotein

S000001836
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:12929-13951:1:exon

YFL056C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YFL057C
gene: AAD6
locus tag: YFL056C
gene synonym: YFL057C
note: Putative aryl-alcohol dehydrogenase; involved in oxidative stress response; similar to P. chrysosporium aryl-alcohol dehydrogenase; ORFs AAD6/YFL056C and AAD16/YFL057C are displaced from one another by -1 frameshift; members of the AAD gene family comprise three pairs (AAD3 + AAD15, AAD6/AAD16 + AAD4, AAD10 + AAD14) whose two genes are more related to one another than to other members of the family; expression induced in cells treated with the mycotoxin patulin
pseudo: true
so part of: sequence
location: complement(14305..15431)
location: region:14305-15431:-1
so has part: feature:14305-15431:-1:exon

850488
type: Gene
SIO_000068: ncbigene

S000001838
type: SGD
SIO_000068: sgd

position:14305:-1
position: 14305
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:15431:-1
position: 15431
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:14305-15431:-1:exon

YFL056C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YFL057C
gene: AAD6
locus tag: YFL056C
gene synonym: YFL057C
pseudo: true
SIO_010081: YFL056C
subclass of: SO_0000673
so part of: YFL056C
location: complement(14305..15431)
location: region:14305-15431:-1
so has part: feature:14305-15431:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:14305-15431:-1:exon

YFL055W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: AGP3
locus tag: YFL055W
so part of: sequence
location: <17004..>18680
location: region:17004-18680:1
so has part: feature:17004-18680:1:exon
subclass of: SO_0000010

850489
type: Gene
SIO_000068: ncbigene

position:17004:1
position: 17004
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:18680:1
position: 18680
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:17004-18680:1:exon

YFL055W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: AGP3
locus tag: YFL055W
product: Agp3p
transcript id: NM_001179912.1
SIO_010081: YFL055W
subclass of: SO_0000673
so part of: YFL055W
location: <17004..>18680
location: region:17004-18680:1
so has part: feature:17004-18680:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:17004-18680:1:exon

YFL055W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: AGP3
locus tag: YFL055W
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0006865 amino acid transport [PMID:10654085]
experiment: EXISTENCE:direct assay:GO:0015171 amino acid transmembrane transporter activity [PMID:10654085]
experiment: EXISTENCE:direct assay:GO:0055085 transmembrane transport [PMID:10654085]
experiment: EXISTENCE:mutant phenotype:GO:0006865 amino acid transport [PMID:14697254]
experiment: EXISTENCE:mutant phenotype:GO:0015171 amino acid transmembrane transporter activity [PMID:14697254]
note: Low-affinity amino acid permease; may act to supply the cell with amino acids as nitrogen source in nitrogen-poor conditions; transcription is induced under conditions of sulfur limitation; plays a role in regulating Ty1 transposition
codon start: 1
product: Agp3p
translation: MAVLNLKRETVDIEETAKKDIKPYFASNVEAVDIDEDPDVSRYDPQTGVKRALKNRHISLLALGGVIGPGCLVGAGNALNKGGPLALLLGFSIIGIIAFSVMESIGEMITLYPSGGGFTTLARRFHSDALPAVCGYAYVVVFFAVLANEYNTLSSILQFWGPQVPLYGYILIFWFAFEIFQLVGVGLFGETEYWLAWLKIVGLVAYYIFSIVYISGDIRNRPAFGFHYWNSPGALSHGFKGIAIVFVFCSTFYSGTESVALAATESKNPGKAVPLAVRQTLWRILVVYIGIAVFYGATVPFDDPNLSASTKVLKSPIAIAISRAGWAGGAHLVNAFILITCISAINGSLYIGSRTLTHLAHEGLAPKILAWTDRRGVPIPAITVFNALGLISLMNVSVGAANAYSYIVNLSGVGVFIVWGVISYTHLRIRKAWVAQGRSIEELPYEALFYPWTPVLSLAANIFLALIQGWSYFVPFDAGNFVDAYILLPVGILLYIGICVFKSNHFRTVDLRSINLDEGRRKDMEADLSDQESSLASSETMKDYKSATFFRYLSNIFT
SIO_010081: YFL055W
subclass of: SO_0000673
so part of: YFL055W
location: 17004..18680
location: region:17004-18680:1
so has part: feature:17004-18680:1:exon

NP_116600.1
type: Protein
SIO_000068: ncbiprotein

S000001839
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:17004-18680:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS600.4; Strong autonomously replicating sequence
so part of: sequence
location: 20702..20900
location: region:20702-20900:1
so has part: feature:20702-20900:1:region

S000178094
type: SGD
SIO_000068: sgd

position:20702:1
position: 20702
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:20900:1
position: 20900
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:20702-20900:1:region

YFL054C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: AQY3
locus tag: YFL054C
so part of: sequence
location: complement(<20847..>22787)
location: region:20847-22787:-1
so has part: feature:20847-22787:-1:exon
subclass of: SO_0000010

850490
type: Gene
SIO_000068: ncbigene

position:20847:-1
position: 20847
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:22787:-1
position: 22787
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:20847-22787:-1:exon

YFL054C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: AQY3
locus tag: YFL054C
product: Aqy3p
transcript id: NM_001179913.1
SIO_010081: YFL054C
subclass of: SO_0000673
so part of: YFL054C
location: complement(<20847..>22787)
location: region:20847-22787:-1
so has part: feature:20847-22787:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:20847-22787:-1:exon

YFL054C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: AQY3
locus tag: YFL054C
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0015254 glycerol channel activity [PMID:12832087]
experiment: EXISTENCE:mutant phenotype:GO:0055085 transmembrane transport [PMID:12832087]
note: Putative channel-like protein; similar to Fps1p; mediates passive diffusion of glycerol in the presence of ethanol
codon start: 1
product: Aqy3p
translation: MSYESGRSSSSSESTRPPTLKEEPNGKIAWEESVKKSRENNENDSTLLRRKLGETRKAIETGGSSRNKLSALTPLKKVVDERKDSVQPQVPSMGFTYSLPNLKTLNSFSDAEQARIMQDYLSRGVNQGNSNNYVDPLYRQLNPTMGSSRNRPVWSLNQPLPHVLDRGLAAKMIQKNMDARSRASSRRGSTDISRGGSTTSVKDWKRLLRGAAPGKKLGDIEAQTQRDNTVGADVKPTKLEPENPQKPSNTHIENVSRKKKRTSHNVNFSLGDESYASSIADAESRKLKNMQTLDGSTPVYTKLPEELIEEENKSTSALDGNEIGASEDEDADIMTFPNFWAKIRYHMREPFAEFLGTLVLVIFGVGGNLQATVTKGSGGSYESLSFAWGFGCMLGVYVAGGISGGHINPAVTISMAIFRKFPWKKVPVYIVAQIIGAYFGGAMAYGYFWSSITEFEGGPHIRTTATGACLFTDPKSYVTWRNAFFDEFIGASILVGCLMALLDDSNAPPGNGMTALIIGFLVAAIGMALGYQTSFTINPARDLGPRIFASMIGYGPHAFHLTHWWWTWGAWGGPIAGGIAGALIYDIFIFTGCESPVNYPDNGYIENRVGKLLHAEFHQNDGTVSDESGVNSNSNTGSKKSVPTSS
SIO_010081: YFL054C
subclass of: SO_0000673
so part of: YFL054C
location: complement(20847..22787)
location: region:20847-22787:-1
so has part: feature:20847-22787:-1:exon

NP_116601.1
type: Protein
SIO_000068: ncbiprotein

S000001840
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:20847-22787:-1:exon

YFL053W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: DAK2
locus tag: YFL053W
so part of: sequence
location: <23423..>25198
location: region:23423-25198:1
so has part: feature:23423-25198:1:exon
subclass of: SO_0000010

850491
type: Gene
SIO_000068: ncbigene

position:23423:1
position: 23423
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:25198:1
position: 25198
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:23423-25198:1:exon

YFL053W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: DAK2
locus tag: YFL053W
product: dihydroxyacetone kinase
transcript id: NM_001179914.1
SIO_010081: YFL053W
subclass of: SO_0000673
so part of: YFL053W
location: <23423..>25198
location: region:23423-25198:1
so has part: feature:23423-25198:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:23423-25198:1:exon

YFL053W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: DAK2
locus tag: YFL053W
EC number: 2.7.1.28
EC number: 2.7.1.29
experiment: EXISTENCE:genetic interaction:GO:0004371 glycerone kinase activity [PMID:12401799]
experiment: EXISTENCE:genetic interaction:GO:0061610 glycerol to glycerone phosphate metabolic process [PMID:22979944]
experiment: EXISTENCE:mutant phenotype:GO:0004371 glycerone kinase activity [PMID:12401799]
experiment: EXISTENCE:mutant phenotype:GO:0097237 cellular response to toxic substance [PMID:12401799]
note: Dihydroxyacetone kinase; required for detoxification of dihydroxyacetone (DHA); involved in stress adaptation
codon start: 1
product: dihydroxyacetone kinase
translation: MSHKQFKSDGNIVTPYLLGLARSNPGLTVIKHDRVVFRTASAPNSGNPPKVSLVSGGGSGHEPTHAGFVGEGALDAIAAGAIFASPSTKQIYSAIKAVESPKGTLIIVKNYTGDIIHFGLAAERAKAAGMKVELVAVGDDVSVGKKKGSLVGRRGLGATVLVHKIAGAAASHGLELAEVAEVAQSVVDNSVTIAASLDHCTVPGHKPEAILGENEYEIGMGIHNESGTYKSSPLPSISELVSQMLPLLLDEDEDRSYVKFEPKEDVVLMVNNMGGMSNLELGYAAEVISEQLIDKYQIVPKRTITGAFITALNGPGFGITLMNASKAGGDILKYFDYPTTASGWNQMYHSAKDWEVLAKGQVPTAPSLKTLRNEKGSGVKADYDTFAKILLAGIAKINEVEPKVTWYDTIAGDGDCGTTLVSGGEALEEAIKNHTLRLEDAALGIEDIAYMVEDSMGGTSGGLYSIYLSALAQGVRDSGDKELTAETFKKASNVALDALYKYTRARPGYRTLIDALQPFVEALKAGKGPRAAAQAAYDGAEKTRKMDALVGRASYVAKEELRKLDSEGGLPDPGAVGLAALLDGFVTAAGY
SIO_010081: YFL053W
subclass of: SO_0000673
so part of: YFL053W
location: 23423..25198
location: region:23423-25198:1
so has part: feature:23423-25198:1:exon

NP_116602.1
type: Protein
SIO_000068: ncbiprotein

S000001841
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:23423-25198:1:exon

YFL052W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ZNF1
locus tag: YFL052W
so part of: sequence
location: <28232..>29629
location: region:28232-29629:1
so has part: feature:28232-29629:1:exon
subclass of: SO_0000010

850492
type: Gene
SIO_000068: ncbigene

position:28232:1
position: 28232
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:29629:1
position: 29629
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:28232-29629:1:exon

YFL052W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ZNF1
locus tag: YFL052W
product: DNA-binding domain containing protein
transcript id: NM_001179915.1
SIO_010081: YFL052W
subclass of: SO_0000673
so part of: YFL052W
location: <28232..>29629
location: region:28232-29629:1
so has part: feature:28232-29629:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:28232-29629:1:exon

YFL052W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ZNF1
locus tag: YFL052W
experiment: EXISTENCE:curator inference:GO:0005634 nucleus [PMID:25673751]
experiment: EXISTENCE:direct assay:GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding [PMID:25673751]
experiment: EXISTENCE:mutant phenotype:GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific [PMID:25673751]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:25673751]
note: Zinc cluster transcription factor that regulates respiratory growth; binds to promoters of genes involved in respiration, gluconeogenesis, and the glyoxylate shunt; required for normal carbon source utilization and adaptation to pH, osmotic and ethanol stress especially during non-fermentative metabolism
codon start: 1
product: DNA-binding domain containing protein
translation: MARNRQACDCCCIRRVKCDRKKPCKCCLQHNLQCTYLRPLKKRGPKPVKVRNLKKVDDVQVFSKSSSGGIMKVPKALIDQCLRLYNDKLYVIWPLLCYDDLYELLEKRYDETCVYWFLVSLSAATLSDLQTEIESEGGVTFTGIQLSSFCMSSRQEFDDFNGSDIFKIMTYYCLNRCYAQMSNSRTSYRLSCEAVGLIKLAGFHREETLKLLPFDEQQLGRKVYYLLLLTERYFSVYTHCATSLDTTIAPPQPENVTDPRLSLDSFLEMIRVFTVPGKCFFDALATDSANVTCTEDSLKKIWRELHTVPLEIEPWSYGYVDISFSRHWIRTLAWKLVLQISGMRISFLSNSKNTHIPVEIARDMLEDTFLIPKNLYAVHGPGISVKALEIADALVDVVNQYDQNAESEAWNFLFDISKFVFSLKHCDSTLVDKFTTKCQCALITLPLSNPLESTDGSKEDVDALP
SIO_010081: YFL052W
subclass of: SO_0000673
so part of: YFL052W
location: 28232..29629
location: region:28232-29629:1
so has part: feature:28232-29629:1:exon

NP_116603.1
type: Protein
SIO_000068: ncbiprotein

S000001842
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:28232-29629:1:exon

YFL051C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YFL051C
so part of: sequence
location: complement(<30058..>30540)
location: region:30058-30540:-1
so has part: feature:30058-30540:-1:exon
subclass of: SO_0000010

850493
type: Gene
SIO_000068: ncbigene

position:30058:-1
position: 30058
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:30540:-1
position: 30540
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:30058-30540:-1:exon

YFL051C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YFL051C
product: uncharacterized protein
transcript id: NM_001179916.1
SIO_010081: YFL051C
subclass of: SO_0000673
so part of: YFL051C
location: complement(<30058..>30540)
location: region:30058-30540:-1
so has part: feature:30058-30540:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:30058-30540:-1:exon

YFL051C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YFL051C
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
note: hypothetical protein; SWAT-GFP fusion protein localizes to the cell periphery while mCherry fusion protein localizes to both the cell periphery and vacuole; YFL051C is not an essential gene
codon start: 1
product: uncharacterized protein
translation: MSIPHSVFSALLVFVALATTTLASTEACLPTNKREDGMNINFYEYTIGDQTTYLEPEYMGYEYSNTKKLGSVSGQTNLSIYYSPPCESTPTCVTYAVLKRDEDGYDPCGPLYETKKRDTEYCDPNTAYWSSDLFGFYTTPTNVTVEMTGYLIWSMGNRRR
SIO_010081: YFL051C
subclass of: SO_0000673
so part of: YFL051C
location: complement(30058..30540)
location: region:30058-30540:-1
so has part: feature:30058-30540:-1:exon

NP_116576.1
type: Protein
SIO_000068: ncbiprotein

S000001843
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:30058-30540:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS601; Autonomously replicating sequence on Chromosome VI; overlaps ARS602, ARS601/ARS602 together appear to be activated during the second half of S phase in 32% of cell cycles
so part of: sequence
location: 32473..32995
location: region:32473-32995:1
so has part: feature:32473-32995:1:region

S000007633
type: SGD
SIO_000068: sgd

position:32473:1
position: 32473
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:32995:1
position: 32995
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:32473-32995:1:region

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS602; Autonomously replicating sequence on Chromosome VI; overlaps ARS601, ARS601/ARS602 together appear to be activated during the second half of S phase in 32% of cell cycles
so part of: sequence
location: 32667..33247
location: region:32667-33247:1
so has part: feature:32667-33247:1:region

S000007634
type: SGD
SIO_000068: sgd

position:32667:1
position: 32667
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:33247:1
position: 33247
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:32667-33247:1:region

YFL050C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ALR2
locus tag: YFL050C
so part of: sequence
location: complement(<33272..>35848)
location: region:33272-35848:-1
so has part: feature:33272-35848:-1:exon
subclass of: SO_0000010

850494
type: Gene
SIO_000068: ncbigene

position:33272:-1
position: 33272
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:35848:-1
position: 35848
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:33272-35848:-1:exon

YFL050C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ALR2
locus tag: YFL050C
product: putative Mg(2+) transporter ALR2
transcript id: NM_001179917.1
SIO_010081: YFL050C
subclass of: SO_0000673
so part of: YFL050C
location: complement(<33272..>35848)
location: region:33272-35848:-1
so has part: feature:33272-35848:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:33272-35848:-1:exon

YFL050C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ALR2
locus tag: YFL050C
experiment: EXISTENCE:direct assay:GO:0015693 magnesium ion transport [PMID:12167543]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0005886 plasma membrane [PMID:9430719]
experiment: EXISTENCE:mutant phenotype:GO:0006812 cation transport [PMID:9430719]
experiment: EXISTENCE:mutant phenotype:GO:0022890 inorganic cation transmembrane transporter activity [PMID:9430719]
experiment: EXISTENCE:mutant phenotype:GO:0055085 transmembrane transport [PMID:9430719]
note: Probable Mg(2+) transporter; overexpression confers increased tolerance to Al(3+) and Ga(3+) ions; plays a role in regulating Ty1 transposition
codon start: 1
product: putative Mg(2+) transporter ALR2
translation: MSSLSTSFDSSSDLPRSKSVDNTAASMKTGKYPKLENYRQYSDAQPIRHEALALKVDETKDSRHKFSSSNGENSGVENGGYVEKTNISTSGRMDFEGEAEAEAVKRYQLRSFALLSSNARPSRLAKSETHQKQIHVESIAPSLPKNAALERGHDTALPAGTSSNRCNLEASSSARTFTSARKASLVSAIFETSAESEHGTHPKQAKLKRRTYSTISTHSSVNPTTLLTRTASQKSDMGNDTRRIKPLRMDSRVSFHSEISQASRDSQETEEDVCFPMFRLLHTRVNGVDFDELEEYAQISNAERNLSLANHQRHSERTYNHTDQDTGFTNSASTSGSSAALKYTPEISRTLEKNCSVNEMYVSENNESVREDDKPDLHPDVTFGRNKIEGEKEGNDSSYSRAYYTLQNTEYQIPSRFSFFRSESDETVHASDIPSLISEGQTFYELFKGGDPTWWLDCSCPTDDEMRCIAKTFGIHPLTAEDIRMQETREKVELFKSYYFVCFHTFENDKESENYLEPINVYIVVFRSGVLTFHFDPISHCANVRRRVRQLRDYVSVNSDWLCYALIDDITDSFAPVIQSIEYEADSIDDSVFMTRDMDFAAMLQRIGESRRKTMTLMRLLSGKADVIKMFAKRCQDETNGIGPVLKSQTNMVNLQAEQENVNQNNSNNQISLSNSYMQTTSQPRGDIALYLGDIQDHLLTMFQNLLAYEKIFSRSHANYLAQLQVESFNSNNKVTEMLGKVTMLGTMLVPLNVITGLFGMNVKVPGRNGSIAWWYGILGVLLLLAVISWFLASYWIKKIDPPATLNEAAGSGAKSVISSFLPKRDKRFNDDSKNGNARVGVRRKSTVSLPSRYSRYN
SIO_010081: YFL050C
subclass of: SO_0000673
so part of: YFL050C
location: complement(33272..35848)
location: region:33272-35848:-1
so has part: feature:33272-35848:-1:exon

NP_116604.1
type: Protein
SIO_000068: ncbiprotein

S000001844
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:33272-35848:-1:exon

YFL049W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SWP82
locus tag: YFL049W
so part of: sequence
location: <36803..>38674
location: region:36803-38674:1
so has part: feature:36803-38674:1:exon
subclass of: SO_0000010

850495
type: Gene
SIO_000068: ncbigene

position:36803:1
position: 36803
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:38674:1
position: 38674
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:36803-38674:1:exon

YFL049W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SWP82
locus tag: YFL049W
product: Swp82p
transcript id: NM_001179918.1
SIO_010081: YFL049W
subclass of: SO_0000673
so part of: YFL049W
location: <36803..>38674
location: region:36803-38674:1
so has part: feature:36803-38674:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:36803-38674:1:exon

YFL049W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SWP82
locus tag: YFL049W
experiment: EXISTENCE:curator inference:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:18644858]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22932476|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0006338 chromatin remodeling [PMID:16204215]
experiment: EXISTENCE:direct assay:GO:0016514 SWI/SNF complex [PMID:16464826|PMID:18644858|PMID:8127913|PMID:16204215]
note: Member of the SWI/SNF chromatin remodeling complex; has an as yet unidentified role in the complex; has identifiable counterparts in closely related yeast species; abundantly expressed in many growth conditions; paralog of Npl6p; relocates to the cytosol under hypoxic conditions
codon start: 1
product: Swp82p
translation: MLGEDEGNTVLEKGNNPSVKQGEVGAVFIVPKILIREHERVILKQILQILDQDELVQPPLDKFPYKKLELPKYIDELKTRDATNTSYKMIQLDAYGEKKVGSNGELFGGRHYLFNTFTFTAHMGVLLVLLQDVIKVLYQSNATHDEDEFIVQHDQILVMETSEEQTKFLAKNGVIPEESKGSFKYITARSAFVEFGASVIAGGQRIVDDYWESLAKKQNLSSHQRVFKLSTNLISKISLLRPSFQNNRISNANEISANTNNTCTISTSKFESQYPIVTEQPSAEIREAYIENFAKGEHISAIVPGQSISGTLELSAQFRVPRYHSKNSFQQALQMKAMDIPIGRHEELLAQYESQAPDGSASISLPNHIPSVNPSNKPIKRMLSSILDINVSSSKNKKSEENEMIKPMNKGQHKNNTSLNINGWKFESLPLKSAENSGKQQYYRGLPLYEKNTLLERLKQLTPNEIKELEHLHDAVFVNTGLQNVRKVRTKKWKKYWQYKAGIPIGLKRSQLDEFKNKYLKDVLAQTSVTTNFNEITNTDETITTKRVPNPNFLGNCNIKDFKPPYIYSHVNKVPQNVAGDKTAVKLDTEVKNTNANPVVATDPVAAKPDNLANFSNEVAMNN
SIO_010081: YFL049W
subclass of: SO_0000673
so part of: YFL049W
location: 36803..38674
location: region:36803-38674:1
so has part: feature:36803-38674:1:exon

NP_116605.1
type: Protein
SIO_000068: ncbiprotein

S000001845
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:36803-38674:1:exon

YFL048C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: EMP47
locus tag: YFL048C
so part of: sequence
location: complement(<38843..>40180)
location: region:38843-40180:-1
so has part: feature:38843-40180:-1:exon
subclass of: SO_0000010

850496
type: Gene
SIO_000068: ncbigene

position:38843:-1
position: 38843
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:40180:-1
position: 40180
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:38843-40180:-1:exon

YFL048C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: EMP47
locus tag: YFL048C
product: Emp47p
transcript id: NM_001179919.1
SIO_010081: YFL048C
subclass of: SO_0000673
so part of: YFL048C
location: complement(<38843..>40180)
location: region:38843-40180:-1
so has part: feature:38843-40180:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:38843-40180:-1:exon

YFL048C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: EMP47
locus tag: YFL048C
experiment: EXISTENCE:direct assay:GO:0000139 Golgi membrane [PMID:12857885]
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:12857885]
experiment: EXISTENCE:direct assay:GO:0030134 COPII-coated ER to Golgi transport vesicle [PMID:11157978]
experiment: EXISTENCE:direct assay:GO:0097367 carbohydrate derivative binding [PMID:16439369]
experiment: EXISTENCE:genetic interaction:GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport [PMID:12857885]
note: Integral membrane component of ER-derived COPII-coated vesicles; functions in ER to Golgi transport; forms a complex with Ssp120p that may function in trafficking plasma membrane glycoproteins through early secretory pathway; EMP47 has a paralog, EMP46, that arose from the whole genome duplication
codon start: 1
product: Emp47p
translation: MMMLITMKSTVLLSVFTVLATWAGLLEAHPLGDTSDASKLSSDYSLPDLINARKVPNNWQTGEQASLEEGRIVLTSKQNSKGSLWLKQGFDLKDSFTMEWTFRSVGYSGQTDGGISFWFVQDSNVPRDKQLYNGPVNYDGLQLLVDNNGPLGPTLRGQLNDGQKPVDKTKIYDQSFASCLMGYQDSSVPSTIRVTYDLEDDNLLKVQVDNKVCFQTRKVRFPSGSYRIGVTAQNGAVNNNAESFEIFKMQFFNGVIEDSLIPNVNAMGQPKLITKYIDQQTGKEKLIEKTAFDADKDKITNYELYKKLDRVEGKILANDINALETKLNDVIKVQQELLSFMTTITKQLSSKPPANNEKGTSTDDAIAEDKENFKDFLSINQKLEKVLVEQEKYREATKRHGQDGPQVDEIARKLMIWLLPLIFIMLVMAYYTFRIRQEIIKTKLL
SIO_010081: YFL048C
subclass of: SO_0000673
so part of: YFL048C
location: complement(38843..40180)
location: region:38843-40180:-1
so has part: feature:38843-40180:-1:exon

NP_116606.1
type: Protein
SIO_000068: ncbiprotein

S000001846
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:38843-40180:-1:exon

YFL047W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RGD2
locus tag: YFL047W
so part of: sequence
location: <40421..>42565
location: region:40421-42565:1
so has part: feature:40421-42565:1:exon
subclass of: SO_0000010

850497
type: Gene
SIO_000068: ncbigene

position:40421:1
position: 40421
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:42565:1
position: 42565
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:40421-42565:1:exon

YFL047W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RGD2
locus tag: YFL047W
product: GTPase-activating protein RGD2
transcript id: NM_001179920.1
SIO_010081: YFL047W
subclass of: SO_0000673
so part of: YFL047W
location: <40421..>42565
location: region:40421-42565:1
so has part: feature:40421-42565:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:40421-42565:1:exon

YFL047W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RGD2
locus tag: YFL047W
experiment: EXISTENCE:curator inference:GO:0007264 small GTPase mediated signal transduction [PMID:11591390]
experiment: EXISTENCE:direct assay:GO:0005096 GTPase activator activity [PMID:11591390]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095|PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005934 cellular bud tip [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:14562095|PMID:22842922]
experiment: EXISTENCE:physical interaction:GO:0007264 small GTPase mediated signal transduction [PMID:11591390]
note: GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p; relocalizes from bud neck to cytoplasm upon DNA replication stress
codon start: 1
product: GTPase-activating protein RGD2
translation: MLSFCDYFWSEDLVSGLDVLFDRLYHGCEQCDLFIQLFASRMQFEVSHGRQLFGIEAGMDNLKAVQEDEDEGVTVSRALRGILQEMSQEGTHHLTIASNIESLVLQPFSKWCIEHRERIQYSEKTLLTNVNNFRKSKKYVGKLEKEYFNKCRQLEEFKRTHFNEDELANAMKSLKIQNKYEEDVAREKDHRFFNRIAGIDFDYKTMKETLQLLLTKLPKTDYKLPLISYSLSNTNNGGEITKFLLDHMSLKDIDQAETFGQDLLNLGFLKYCNGVGNTFVNSKKFQYQWKNTAYMFANVPMPGSEEPTTGESLISRFNNWDGSSAKEIIQSKIGNDQGAAKIQAPHISDNERTLFRMMDALAASDKKYYQECFKMDALRCSVEELLIDHLSFMEKCESDRLNAIKKATLDFCSTLGNKISSLRLCIDKMLTLENDIDPTADLLQLLVKYKTGSFKPQAIVYNNYYNPGSFQNFGVDLETRCRLDKKVVPLIISSIFSYMDKIYPDLPNDKVRTSIWTDSVKLSLTHQLRNLLNKQQFHNEGEIFDILSTSKLEPSTIASVVKIYLLELPDPLIPNDVSDILRVLYLDYPPLVETALQNSTSSPENQQDDDNEEGFDTKRIRGLYTTLSSLSKPHIATLDAITTHFYRLIKILKMGENGNEVADEFTVSISQEFANCIIQSKITDDNEIGFKIFYDLLTHKKQIFHELKRQNSKN
SIO_010081: YFL047W
subclass of: SO_0000673
so part of: YFL047W
location: 40421..42565
location: region:40421-42565:1
so has part: feature:40421-42565:1:exon

NP_428268.1
type: Protein
SIO_000068: ncbiprotein

S000001847
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:40421-42565:1:exon

YFL046W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PUT6
gene: FMP32
locus tag: YFL046W
gene synonym: PUT6
so part of: sequence
location: <42815..>43438
location: region:42815-43438:1
so has part: feature:42815-43438:1:exon
subclass of: SO_0000010

850498
type: Gene
SIO_000068: ncbigene

position:42815:1
position: 42815
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:43438:1
position: 43438
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:42815-43438:1:exon

YFL046W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PUT6
gene: FMP32
locus tag: YFL046W
gene synonym: PUT6
product: Fmp32p
transcript id: NM_001179921.1
SIO_010081: YFL046W
subclass of: SO_0000673
so part of: YFL046W
location: <42815..>43438
location: region:42815-43438:1
so has part: feature:42815-43438:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:42815-43438:1:exon

YFL046W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PUT6
gene: FMP32
locus tag: YFL046W
gene synonym: PUT6
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:12514182|PMID:14576278|PMID:16823961|PMID:24769239|P MID:26928762]
experiment: EXISTENCE:direct assay:GO:0005743 mitochondrial inner membrane [PMID:32978391]
experiment: EXISTENCE:mutant phenotype:GO:0033617 mitochondrial cytochrome c oxidase assembly [PMID:25565209]
experiment: EXISTENCE:mutant phenotype:GO:2000214 regulation of proline metabolic process [PMID:32978391]
note: Regulator of mitochondrial proline metabolism; tethered with Put7p to inner mitochondrial membrane in large hetero-oligomeric complex, abundance of which is regulated by proline; involved in mitochondrial proline homeostasis and cellular redox balance; null exhibits pronounced defect in proline utilization, and can be functionally complemented by expression of human homolog MCUR1
codon start: 1
product: Fmp32p
translation: MLKRIVGLPARRCFHRTSFLLGSDFETVHIPNTNHFKDLLIENGKFQEDQATTIVEIMTDAIRGGVNHVSQDLAKREKLTQLSYQQRVDFAKLRDQLLSADRSEFHNIQNEYESVKNDLEKLRNKLREEITKTNAGFKLDLSLEKGRIREESSHHDLQIKEIDTKIEQEVTNMKMQIDSVKTQVMQWLIGVCTGTFALVLAYMRLLT
SIO_010081: YFL046W
subclass of: SO_0000673
so part of: YFL046W
location: 42815..43438
location: region:42815-43438:1
so has part: feature:42815-43438:1:exon

NP_116608.1
type: Protein
SIO_000068: ncbiprotein

S000001848
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:42815-43438:1:exon

YFL045C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ALG4
gene: SEC53
locus tag: YFL045C
gene synonym: ALG4
so part of: sequence
location: complement(<43628..>44392)
location: region:43628-44392:-1
so has part: feature:43628-44392:-1:exon
subclass of: SO_0000010

850499
type: Gene
SIO_000068: ncbigene

position:43628:-1
position: 43628
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:44392:-1
position: 44392
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:43628-44392:-1:exon

YFL045C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ALG4
gene: SEC53
locus tag: YFL045C
gene synonym: ALG4
product: phosphomannomutase SEC53
transcript id: NM_001179922.1
SIO_010081: YFL045C
subclass of: SO_0000673
so part of: YFL045C
location: complement(<43628..>44392)
location: region:43628-44392:-1
so has part: feature:43628-44392:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:43628-44392:-1:exon

YFL045C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ALG4
gene: SEC53
locus tag: YFL045C
gene synonym: ALG4
EC number: 5.4.2.8
experiment: EXISTENCE:direct assay:GO:0004615 phosphomannomutase activity [PMID:3288631]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:3905826]
experiment: EXISTENCE:direct assay:GO:0010494 cytoplasmic stress granule [PMID:26777405]
note: Phosphomannomutase; involved in synthesis of GDP-mannose and dolichol-phosphate-mannose; required for folding and glycosylation of secretory proteins in the ER lumen; human homolog PMM2 complements yeast mutants
codon start: 1
product: phosphomannomutase SEC53
translation: MSIAEFAYKEKPETLVLFDVDGTLTPARLTVSEEVRKTLAKLRNKCCIGFVGGSDLSKQLEQLGPNVLDEFDYSFSENGLTAYRLGKELASQSFINWLGEEKYNKLAVFILRYLSEIDLPKRRGTFLEFRNGMINVSPIGRNASTEERNEFERYDKEHQIRAKFVEALKKEFPDYGLTFSIGGQISFDVFPAGWDKTYCLQHVEKDGFKEIHFFGDKTMVGGNDYEIFVDERTIGHSVQSPDDTVKILTELFNL
SIO_010081: YFL045C
subclass of: SO_0000673
so part of: YFL045C
location: complement(43628..44392)
location: region:43628-44392:-1
so has part: feature:43628-44392:-1:exon

NP_116609.1
type: Protein
SIO_000068: ncbiprotein

S000001849
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:43628-44392:-1:exon

YFL044C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: OTU1
locus tag: YFL044C
so part of: sequence
location: complement(<44655..>45560)
location: region:44655-45560:-1
so has part: feature:44655-45560:-1:exon
subclass of: SO_0000010

850500
type: Gene
SIO_000068: ncbigene

position:44655:-1
position: 44655
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:45560:-1
position: 45560
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:44655-45560:-1:exon

YFL044C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: OTU1
locus tag: YFL044C
product: ubiquitin-specific protease OTU1
transcript id: NM_001179923.1
SIO_010081: YFL044C
subclass of: SO_0000673
so part of: YFL044C
location: complement(<44655..>45560)
location: region:44655-45560:-1
so has part: feature:44655-45560:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:44655-45560:-1:exon

YFL044C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: OTU1
locus tag: YFL044C
EC number: 3.4.19.12
experiment: EXISTENCE:direct assay:GO:0004843 cysteine-type deubiquitinase activity [PMID:16427015]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0016579 protein deubiquitination [PMID:16427015]
experiment: EXISTENCE:mutant phenotype:GO:0006355 regulation of DNA-templated transcription [PMID:15755922]
note: Deubiquitylation enzyme that binds to the chaperone-ATPase Cdc48p; may contribute to regulation of protein degradation by deubiquitylating substrates that have been ubiquitylated by Ufd2p; member of the Ovarian Tumor (OTU) family; protein abundance increases in response to DNA replication stress
codon start: 1
product: ubiquitin-specific protease OTU1
translation: MKLKVTGAGINQVVTLKQDATLNDLIEHINVDVKTMRFGYPPQRINLQGEDASLGQTQLDELGINSGEKITIESSDSNESFSLPPPQPKPKRVLKSTEMSIGGSGENVLSVHPVLDDNSCLFHAIAYGIFKQDSVRDLREMVSKEVLNNPVKFNDAILDKPNKDYAQWILKMESWGGAIEIGIISDALAVAIYVVDIDAVKIEKFNEDKFDNYILILFNGIHYDSLTMNEFKTVFNKNQPESDDVLTAALQLASNLKQTGYSFNTHKAQIKCNTCQMTFVGEREVARHAESTGHVDFGQNR
SIO_010081: YFL044C
subclass of: SO_0000673
so part of: YFL044C
location: complement(44655..45560)
location: region:44655-45560:-1
so has part: feature:44655-45560:-1:exon

NP_116610.1
type: Protein
SIO_000068: ncbiprotein

S000001850
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:44655-45560:-1:exon

YFL042C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LTC2
alternative label: YFL043C
gene: LAM5
locus tag: YFL042C
gene synonym: LTC2; YFL043C
so part of: sequence
location: complement(<45720..>47744)
location: region:45720-47744:-1
so has part: feature:45720-47744:-1:exon
subclass of: SO_0000010

850501
type: Gene
SIO_000068: ncbigene

position:45720:-1
position: 45720
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:47744:-1
position: 47744
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:45720-47744:-1:exon

YFL042C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LTC2
alternative label: YFL043C
gene: LAM5
locus tag: YFL042C
gene synonym: LTC2; YFL043C
product: Lam5p
transcript id: NM_001179924.1
SIO_010081: YFL042C
subclass of: SO_0000673
so part of: YFL042C
location: complement(<45720..>47744)
location: region:45720-47744:-1
so has part: feature:45720-47744:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:45720-47744:-1:exon

YFL042C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LTC2
alternative label: YFL043C
gene: LAM5
locus tag: YFL042C
gene synonym: LTC2; YFL043C
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0044233 mitochondria-associated endoplasmic reticulum membrane [PMID:26001273]
experiment: EXISTENCE:direct assay:GO:0071561 nucleus-vacuole junction [PMID:26001273]
note: Putative sterol transfer protein; one of six StART-like domain-containing proteins in yeast that may be involved in sterol transfer between intracellular membranes; conserved across eukaryotes; has both GRAM and StART-like (VASt) domains; localizes to membrane contact sites throughout the cell, including nucleus-vacuole junctions and ER-mitochondrial contact sites
codon start: 1
product: Lam5p
translation: MSDVDNWEPVSDNEDSTDSVKQLGPPFEHASNNDNAGDTEAESLQEVPLNTETNDVRKNLVVITNQSAADEHPTEIKHDQSRTSSTSSFFSGMISSFKSNVPSPVSRSTTPTSPVSQPSIISHRREPSMGSKRRSSRRISNATIAEIGSPLQQVEKPDEVKTRLTPSQMKEDNYDHRRFVEERYMDTPYHYASEQRNKDFHETFKSVPKDDRLLDDFNCGLNRELLYQGKLYITETHLCFNSNVLGWIAKVLIAFEDVTFMEKTSAAGLFPSAISIETKMGKTLFNGFISRDAAFGLMKEVWSRTLLQKDMASENINTKAEKSGNGKEIDDAINSIDEENNDKDANDNDTNENDDENISTNETTPNSTSSSPDKEKEKAYKLRADSSYQYDGPIYHHSTSFPAEPMANNEFVLKELPFDCAPGILFEIMFNSEQNEFLLDFLRGQEGSQITTIPNFTSIDGSSMTLKREYSYEKALHFPAGPKSTTCYVAEVIKRKDPDTYYEVISSIRTPNVPSGGSFSTKTRYLIRWNDEITCLLRVSFWVEWTGSSWIKGMVENGCKNGQLEAAQLMERILSKFIKNNVEECQITISKEEEEQDDKEVKNKLKEVDLEQPREAVVTAPAIAEQQGLKVTMETWLFLYLIVVVLLLFNLFYIRSIAVSLHQLVKLQLVELKL
SIO_010081: YFL042C
subclass of: SO_0000673
so part of: YFL042C
location: complement(45720..47744)
location: region:45720-47744:-1
so has part: feature:45720-47744:-1:exon

NP_116611.1
type: Protein
SIO_000068: ncbiprotein

S000001852
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:45720-47744:-1:exon

YFL041W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YFL041W-A
so part of: sequence
location: <48734..>48925
location: region:48734-48925:1
so has part: feature:48734-48925:1:exon
subclass of: SO_0000010

1466401
type: Gene
SIO_000068: ncbigene

position:48734:1
position: 48734
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:48925:1
position: 48925
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:48734-48925:1:exon

YFL041W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YFL041W-A
product: uncharacterized protein
transcript id: NM_001184549.1
SIO_010081: YFL041W-A
subclass of: SO_0000673
so part of: YFL041W-A
location: <48734..>48925
location: region:48734-48925:1
so has part: feature:48734-48925:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:48734-48925:1:exon

YFL041W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YFL041W-A
note: hypothetical protein; identified by fungal homology and RT-PCR
codon start: 1
product: uncharacterized protein
translation: MKMWGPSQRDSFREITYKVKFKYDDGDYSLAIDLMSRDCINVYELITDRLLVDFLSKKLLKLR
SIO_010081: YFL041W-A
subclass of: SO_0000673
so part of: YFL041W-A
location: 48734..48925
location: region:48734-48925:1
so has part: feature:48734-48925:1:exon

NP_878071.1
type: Protein
SIO_000068: ncbiprotein

S000028547
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:48734-48925:1:exon

YFL041W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FET5
locus tag: YFL041W
so part of: sequence
location: <49139..>51007
location: region:49139-51007:1
so has part: feature:49139-51007:1:exon
subclass of: SO_0000010

850502
type: Gene
SIO_000068: ncbigene

position:49139:1
position: 49139
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:51007:1
position: 51007
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:49139-51007:1:exon

YFL041W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FET5
locus tag: YFL041W
product: ferroxidase FET5
transcript id: NM_001179925.1
SIO_010081: YFL041W
subclass of: SO_0000673
so part of: YFL041W
location: <49139..>51007
location: region:49139-51007:1
so has part: feature:49139-51007:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:49139-51007:1:exon

YFL041W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FET5
locus tag: YFL041W
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:10608875|PMID:24390141|PMID:23836928]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0045121 membrane raft [PMID:23836928]
experiment: EXISTENCE:genetic interaction:GO:0004322 ferroxidase activity [PMID:9413439]
experiment: EXISTENCE:mutant phenotype:GO:0006826 iron ion transport [PMID:9413439]
note: Multicopper oxidase; integral membrane protein with similarity to Fet3p; targeted to vacuole via AP-3 pathway; may have role in iron transport
codon start: 1
product: ferroxidase FET5
translation: MLFYSFVWSVLAASVALAKTHKLNYTASWVTANPDGLHEKRMIGFNGEWPLPDIHVEKGDRVELYLTNGFQDNTATSLHFHGLFQNTSLGNQLQMDGPSMVTQCPIVPGQTYLYNFTVPEQVGTFWYHAHMGAQYGDGMRGAFIIHDPEEPFEYDHERVITLSDHYHENYKTVTKEFLSRYNPTGAEPIPQNILFNNTMNVTLDFTPGETYLFRFLNVGLFVSQYIILEDHEMSIVEVDGVYVKPNFTDSIYLSAGQRMSVLIKAKDKMPTRNYAMMQIMDETMLDVVPPELQLNQTIQMRYGHSLPEARALNIEDCDLDRATNDFYLEPLIERDLLAHYDHQIVMDVRMVNLGDGVKYAFFNNITYVTPKVPTLTTLLTSGKLASDPRIYGDNINAQLLKHNDIIEVVLNNYDSGRHPFHLHGHNFQIVQKSPGFHVDEAYDESEQDEMTVPYNESAPLQPFPERPMVRDTVVLEPSGHVVLRFRADNPGVWYFHCHVDWHLQQGLASVFIEAPVLLQEREKLNENYLDICKAADIPVVGNAAGHSNDWFDLKGLPRQPEPLPKGFTTEGYLALIISTIIGVWGLYSIAQYGIGEVIPNDEKVYHTLREILAENEIEVSRG
SIO_010081: YFL041W
subclass of: SO_0000673
so part of: YFL041W
location: 49139..51007
location: region:49139-51007:1
so has part: feature:49139-51007:1:exon

NP_116612.1
type: Protein
SIO_000068: ncbiprotein

S000001853
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:49139-51007:1:exon

YFL040W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YFL040W
so part of: sequence
location: <51350..>52972
location: region:51350-52972:1
so has part: feature:51350-52972:1:exon
subclass of: SO_0000010

850503
type: Gene
SIO_000068: ncbigene

position:51350:1
position: 51350
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:52972:1
position: 52972
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:51350-52972:1:exon

YFL040W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YFL040W
product: uncharacterized protein
transcript id: NM_001179926.1
SIO_010081: YFL040W
subclass of: SO_0000673
so part of: YFL040W
location: <51350..>52972
location: region:51350-52972:1
so has part: feature:51350-52972:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:51350-52972:1:exon

YFL040W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YFL040W
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005628 prospore membrane [PMID:24390141]
note: Putative transporter; member of the sugar porter family; YFL040W is not an essential gene; may have a role in intracellular sterol transport
codon start: 1
product: uncharacterized protein
translation: MTAMKAIVWRLPKMPKIKITKTYEVTKITAILTLVGFIMGLEVPSLATFLTNKTFNEYFKYPTPLQQGLLMGSTPLGGIMGCFICCIMNDRFSRIYQFQSGIIIWNIVTLLNFCIWDILGLLICRMIKGMILGNFSILVASYANEVIPRGKRGSTMSYIQLCLTIGILVMHYLCIALSLWDSHFAFRIAWCIGIIPGLLFWMASYALPESYHWLVLHGKMSEAQEIQHNLAKKFNESQPRDAVPEMSKIELAGDFWIGVNDLDFSKKLPRGSFKPLILGMTLQLLVQFSGINIILGYITYICEIVGLEGNVKLFTSSIPYFINMVLSLLPITFIDYTSRKLITLLGGFPISGLLITIGALFVKYGQDTKPIDGNRSLVWSIGENPFVGGWILTLCFLIVGIFAMSLSSIPWVYTNEMLPSRVKVKGFAICVTFGWLGNFILTFLCPVMIERLKGTTFIIFGSLTFLISLSVLIWFPETKGMSIEDIDKFFEFESKEGTNLHGEKGIKTPDSNSNGGSTRSSQEGQLHKPIKLKSDEEMII
SIO_010081: YFL040W
subclass of: SO_0000673
so part of: YFL040W
location: 51350..52972
location: region:51350-52972:1
so has part: feature:51350-52972:1:exon

NP_116613.1
type: Protein
SIO_000068: ncbiprotein

S000001854
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:51350-52972:1:exon

YFL039C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ABY1
alternative label: END7
gene: ACT1
locus tag: YFL039C
gene synonym: ABY1; END7
so part of: sequence
location: complement(<53260..>54696)
location: region:53260-54696:-1
so has part: feature:53260-54696:-1:exon
subclass of: SO_0000010

850504
type: Gene
SIO_000068: ncbigene

position:53260:-1
position: 53260
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:54696:-1
position: 54696
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:53260-54696:-1:exon

YFL039C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ABY1
alternative label: END7
gene: ACT1
locus tag: YFL039C
gene synonym: ABY1; END7
product: actin
transcript id: NM_001179927.1
SIO_010081: YFL039C
subclass of: SO_0000673
so part of: YFL039C
location: complement(join(<53260..54377,54687..>54696))
location: region:53260-54696:-1
so has part: feature:54687-54696:-1:exon
so has part: feature:53260-54377:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:54687-54696:-1:exon

position:54687:-1
position: 54687
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:53260-54377:-1:exon

position:54377:-1
position: 54377
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YFL039C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ABY1
alternative label: END7
gene: ACT1
locus tag: YFL039C
gene synonym: ABY1; END7
experiment: EXISTENCE:direct assay:GO:0000142 cellular bud neck contractile ring [PMID:3967297|PMID:8163554]
experiment: EXISTENCE:direct assay:GO:0000812 Swr1 complex [PMID:14645854|PMID:14690608|PMID:16299513]
experiment: EXISTENCE:direct assay:GO:0005200 structural constituent of cytoskeleton [PMID:6217414]
experiment: EXISTENCE:direct assay:GO:0005884 actin filament [PMID:6217414]
experiment: EXISTENCE:direct assay:GO:0006281 DNA repair [PMID:16135807]
experiment: EXISTENCE:direct assay:GO:0016573 histone acetylation [PMID:10911987]
experiment: EXISTENCE:direct assay:GO:0016887 ATP hydrolysis activity [PMID:8245125]
experiment: EXISTENCE:direct assay:GO:0030476 ascospore wall assembly [PMID:17118118]
experiment: EXISTENCE:direct assay:GO:0030479 actin cortical patch [PMID:3967297|PMID:6365930|PMID:8163554]
experiment: EXISTENCE:direct assay:GO:0032432 actin filament bundle [PMID:3967297|PMID:6365930|PMID:8163554]
experiment: EXISTENCE:direct assay:GO:0035267 NuA4 histone acetyltransferase complex [PMID:10911987|PMID:15485911]
experiment: EXISTENCE:genetic interaction:GO:0009306 protein secretion [PMID:10793147]
experiment: EXISTENCE:genetic interaction:GO:0030010 establishment of cell polarity [PMID:9864365]
experiment: EXISTENCE:genetic interaction:GO:0034599 cellular response to oxidative stress [PMID:17287397]
experiment: EXISTENCE:mutant phenotype:GO:0000011 vacuole inheritance [PMID:8978821]
experiment: EXISTENCE:mutant phenotype:GO:0006897 endocytosis [PMID:8590801]
experiment: EXISTENCE:mutant phenotype:GO:0009306 protein secretion [PMID:10793147]
experiment: EXISTENCE:mutant phenotype:GO:1902404 mitotic actomyosin contractile ring contraction [PMID:9732290]
experiment: EXISTENCE:physical interaction:GO:0031011 Ino80 complex [PMID:10952318|PMID:24034245]
note: Actin, structural protein in cytoskeleton; involved in cell polarization, endocytosis, and other cytoskeletal functions; monomeric actin in the nucleus plays a role in INO80 chromatin remodeling
codon start: 1
product: actin
translation: MDSEVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGIMVGMGQKDSYVGDEAQSKRGILTLRYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPMNPKSNREKMTQIMFETFNVPAFYVSIQAVLSLYSSGRTTGIVLDSGDGVTHVVPIYAGFSLPHAILRIDLAGRDLTDYLMKILSERGYSFSTTAEREIVRDIKEKLCYVALDFEQEMQTAAQSSSIEKSYELPDGQVITIGNERFRAPEALFHPSVLGLESAGIDQTTYNSIMKCDVDVRKELYGNIVMSGGTTMFPGIAERMQKEITALAPSSMKVKIIAPPERKYSVWIGGSILASLTTFQQMWISKQEYDESGPSIVHHKCF
SIO_010081: YFL039C
subclass of: SO_0000673
so part of: YFL039C
location: complement(join(53260..54377,54687..54696))
location: region:53260-54696:-1
so has part: feature:54687-54696:-1:exon
so has part: feature:53260-54377:-1:exon

NP_116614.1
type: Protein
SIO_000068: ncbiprotein

S000001855
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:54687-54696:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:53260-54377:-1:exon

YFL038C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: YPT1
locus tag: YFL038C
so part of: sequence
location: complement(<55366..>55986)
location: region:55366-55986:-1
so has part: feature:55366-55986:-1:exon
subclass of: SO_0000010

850505
type: Gene
SIO_000068: ncbigene

position:55366:-1
position: 55366
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:55986:-1
position: 55986
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:55366-55986:-1:exon

YFL038C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: YPT1
locus tag: YFL038C
product: Rab family GTPase YPT1
transcript id: NM_001179928.1
SIO_010081: YFL038C
subclass of: SO_0000673
so part of: YFL038C
location: complement(<55366..>55986)
location: region:55366-55986:-1
so has part: feature:55366-55986:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:55366-55986:-1:exon

YFL038C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: YPT1
locus tag: YFL038C
experiment: EXISTENCE:direct assay:GO:0000139 Golgi membrane [PMID:10747087]
experiment: EXISTENCE:direct assay:GO:0000149 SNARE binding [PMID:18388317]
experiment: EXISTENCE:direct assay:GO:0000407 phagophore assembly site [PMID:20375281]
experiment: EXISTENCE:direct assay:GO:0003924 GTPase activity [PMID:3311726|PMID:9447979]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:10747087]
experiment: EXISTENCE:direct assay:GO:0005795 Golgi stack [PMID:12802060]
experiment: EXISTENCE:direct assay:GO:0005801 cis-Golgi network [PMID:26906739]
experiment: EXISTENCE:direct assay:GO:0031410 cytoplasmic vesicle [PMID:23129774]
experiment: EXISTENCE:direct assay:GO:0035493 SNARE complex assembly [PMID:8603910]
experiment: EXISTENCE:genetic interaction:GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [PMID:18388317]
experiment: EXISTENCE:genetic interaction:GO:0048194 Golgi vesicle budding [PMID:18388317]
experiment: EXISTENCE:mutant phenotype:GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport [PMID:15689495|PMID:2504726|PMID:7593181]
experiment: EXISTENCE:mutant phenotype:GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [PMID:18388317]
experiment: EXISTENCE:mutant phenotype:GO:0016236 macroautophagy [PMID:20375281]
experiment: EXISTENCE:mutant phenotype:GO:0032258 cytoplasm to vacuole transport by the Cvt pathway [PMID:20375281]
experiment: EXISTENCE:mutant phenotype:GO:0032456 endocytic recycling [PMID:20059749]
experiment: EXISTENCE:mutant phenotype:GO:0034497 protein localization to phagophore assembly site [PMID:26195667]
experiment: EXISTENCE:mutant phenotype:GO:0034498 early endosome to Golgi transport [PMID:20059749]
experiment: EXISTENCE:mutant phenotype:GO:0035494 SNARE complex disassembly [PMID:9157884]
experiment: EXISTENCE:mutant phenotype:GO:0043549 regulation of kinase activity [PMID:26195667]
experiment: EXISTENCE:mutant phenotype:GO:0048211 Golgi vesicle docking [PMID:9545229]
experiment: EXISTENCE:mutant phenotype:GO:0061709 reticulophagy [PMID:26181331]
experiment: EXISTENCE:mutant phenotype:GO:0090114 COPII-coated vesicle budding [PMID:15689495]
experiment: EXISTENCE:mutant phenotype:GO:1900101 regulation of endoplasmic reticulum unfolded protein response [PMID:22844259]
experiment: EXISTENCE:mutant phenotype:GO:1990261 pre-mRNA catabolic process [PMID:22844259]
experiment: EXISTENCE:physical interaction:GO:0000149 SNARE binding [PMID:18388317]
experiment: EXISTENCE:physical interaction:GO:0043549 regulation of kinase activity [PMID:26195667]
note: Rab family GTPase; involved in the ER-to-Golgi step of the secretory pathway; complex formation with the Rab escort protein Mrs6p is required for prenylation of Ypt1p by type II protein geranylgeranyltransferase (Bet2p-Bet4p); binds to unspliced HAC1 mRNA; regulates the unfolded protein response (UPR) by promoting the decay of HAC1 RNA; localizes to the early Golgi, the transitional Golgi and ER membranes, pre-autophagosomal structures, and cytoplasmic vesicles
codon start: 1
product: Rab family GTPase YPT1
translation: MNSEYDYLFKLLLIGNSGVGKSCLLLRFSDDTYTNDYISTIGVDFKIKTVELDGKTVKLQIWDTAGQERFRTITSSYYRGSHGIIIVYDVTDQESFNGVKMWLQEIDRYATSTVLKLLVGNKCDLKDKRVVEYDVAKEFADANKMPFLETSALDSTNVEDAFLTMARQIKESMSQQNLNETTQKKEDKGNVNLKGQSLTNTGGGCC
SIO_010081: YFL038C
subclass of: SO_0000673
so part of: YFL038C
location: complement(55366..55986)
location: region:55366-55986:-1
so has part: feature:55366-55986:-1:exon

NP_116615.1
type: Protein
SIO_000068: ncbiprotein

S000001856
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:55366-55986:-1:exon

YFL037W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ARM10
alternative label: SHE8
gene: TUB2
locus tag: YFL037W
gene synonym: ARM10; SHE8
so part of: sequence
location: <56336..>57709
location: region:56336-57709:1
so has part: feature:56336-57709:1:exon
subclass of: SO_0000010

850506
type: Gene
SIO_000068: ncbigene

position:56336:1
position: 56336
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:57709:1
position: 57709
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:56336-57709:1:exon

YFL037W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ARM10
alternative label: SHE8
gene: TUB2
locus tag: YFL037W
gene synonym: ARM10; SHE8
product: beta-tubulin
transcript id: NM_001179929.1
SIO_010081: YFL037W
subclass of: SO_0000673
so part of: YFL037W
location: <56336..>57709
location: region:56336-57709:1
so has part: feature:56336-57709:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:56336-57709:1:exon

YFL037W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ARM10
alternative label: SHE8
gene: TUB2
locus tag: YFL037W
gene synonym: ARM10; SHE8
experiment: EXISTENCE:curator inference:GO:0000070 mitotic sister chromatid segregation [PMID:9488492]
experiment: EXISTENCE:curator inference:GO:0005828 kinetochore microtubule [PMID:9488492]
experiment: EXISTENCE:curator inference:GO:0005880 nuclear microtubule [PMID:9488492]
experiment: EXISTENCE:curator inference:GO:0005881 cytoplasmic microtubule [PMID:9488492]
experiment: EXISTENCE:curator inference:GO:0030473 nuclear migration along microtubule [PMID:9488492]
experiment: EXISTENCE:curator inference:GO:0045143 homologous chromosome segregation [PMID:9488492]
experiment: EXISTENCE:direct assay:GO:0005200 structural constituent of cytoskeleton [PMID:9488492]
experiment: EXISTENCE:direct assay:GO:0045298 tubulin complex [PMID:9488492]
experiment: EXISTENCE:mutant phenotype:GO:0000022 mitotic spindle elongation [PMID:12181356]
experiment: EXISTENCE:mutant phenotype:GO:0003924 GTPase activity [PMID:8171338]
experiment: EXISTENCE:mutant phenotype:GO:0031122 cytoplasmic microtubule organization [PMID:8171338|PMID:12181356]
experiment: EXISTENCE:mutant phenotype:GO:0090307 mitotic spindle assembly [PMID:12181356|PMID:7806575]
experiment: EXISTENCE:physical interaction:GO:0045298 tubulin complex [PMID:9488492]
note: Beta-tubulin; associates with alpha-tubulin (Tub1p and Tub3p) to form tubulin dimer, which polymerizes to form microtubules; mutation in human ortholog is associated with congenital fibrosis of the extraocular muscles (CFEOM) with polymicrogyria
codon start: 1
product: beta-tubulin
translation: MREIIHISTGQCGNQIGAAFWETICGEHGLDFNGTYHGHDDIQKERLNVYFNEASSGKWVPRSINVDLEPGTIDAVRNSAIGNLFRPDNYIFGQSSAGNVWAKGHYTEGAELVDSVMDVIRREAEGCDSLQGFQITHSLGGGTGSGMGTLLISKIREEFPDRMMATFSVLPSPKTSDTVVEPYNATLSVHQLVEHSDETFCIDNEALYDICQRTLKLNQPSYGDLNNLVSSVMSGVTTSLRYPGQLNSDLRKLAVNLVPFPRLHFFMVGYAPLTAIGSQSFRSLTVPELTQQMFDAKNMMAAADPRNGRYLTVAAFFRGKVSVKEVEDEMHKVQSKNSDYFVEWIPNNVQTAVCSVAPQGLDMAATFIANSTSIQELFKRVGDQFSAMFKRKAFLHWYTSEGMDELEFSEAESNMNDLVSEYQQYQEATVEDDEEVDENGDFGAPQNQDEPITENFE
SIO_010081: YFL037W
subclass of: SO_0000673
so part of: YFL037W
location: 56336..57709
location: region:56336-57709:1
so has part: feature:56336-57709:1:exon

NP_116616.1
type: Protein
SIO_000068: ncbiprotein

S000001857
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:56336-57709:1:exon

YNCF0001C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RUF21
locus tag: YNCF0001C
so part of: sequence
location: complement(57815..58521)
location: region:57815-58521:-1
so has part: feature:57815-58521:-1:exon
subclass of: SO_0000011

9164892
type: Gene
SIO_000068: ncbigene

position:57815:-1
position: 57815
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:58521:-1
position: 58521
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:57815-58521:-1:exon

YNCF0001C
type: Non Coding RNA
subclass of: SO_0000655
RO_0002162: 559292
nc RNA class: other
gene: RUF21
locus tag: YNCF0001C
product: RUF21
note: RNA of Unknown Function
transcript id: NR_132172.1
SIO_010081: YNCF0001C
subclass of: SO_0000673
so part of: YNCF0001C
location: complement(57815..58521)
location: region:57815-58521:-1
so has part: feature:57815-58521:-1:exon

S000130129
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:57815-58521:-1:exon

YFL036W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RPO41
locus tag: YFL036W
so part of: sequence
location: <58782..>62837
location: region:58782-62837:1
so has part: feature:58782-62837:1:exon
subclass of: SO_0000010

850507
type: Gene
SIO_000068: ncbigene

position:58782:1
position: 58782
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:62837:1
position: 62837
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:58782-62837:1:exon

YFL036W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RPO41
locus tag: YFL036W
product: DNA-directed RNA polymerase
transcript id: NM_001179930.1
SIO_010081: YFL036W
subclass of: SO_0000673
so part of: YFL036W
location: <58782..>62837
location: region:58782-62837:1
so has part: feature:58782-62837:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:58782-62837:1:exon

YFL036W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RPO41
locus tag: YFL036W
EC number: 2.7.7.6
experiment: EXISTENCE:direct assay:GO:0003896 DNA primase activity [PMID:26184436]
experiment: EXISTENCE:direct assay:GO:0003899 DNA-directed 5'-3' RNA polymerase activity [PMID:2426263|PMID:3517858]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:24769239|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005759 mitochondrial matrix [PMID:2426263|PMID:3517858]
experiment: EXISTENCE:direct assay:GO:0006269 DNA replication, synthesis of RNA primer [PMID:26184436]
experiment: EXISTENCE:direct assay:GO:0006390 mitochondrial transcription [PMID:21911502]
experiment: EXISTENCE:direct assay:GO:0034245 mitochondrial DNA-directed RNA polymerase complex [PMID:7929382]
experiment: EXISTENCE:direct assay:GO:0042645 mitochondrial nucleoid [PMID:15692048]
experiment: EXISTENCE:mutant phenotype:GO:0000002 mitochondrial genome maintenance [PMID:3517858]
experiment: EXISTENCE:mutant phenotype:GO:0006390 mitochondrial transcription [PMID:3517858]
note: Mitochondrial RNA polymerase; single subunit enzyme similar to those of T3 and T7 bacteriophages; requires a specificity subunit encoded by MTF1 for promoter recognition; Mtf1p interacts with and stabilizes the Rpo41p-promoter complex, enhancing DNA bending and melting to facilitate pre-initiation open complex formation; Rpo41p also synthesizes RNA primers for mitochondrial DNA replication
codon start: 1
product: DNA-directed RNA polymerase
translation: MLRPAYKSLVKTSLLQRRLISSKGSKLFKPSPDSTSTILISEDPLVTGSSPTSSTTSGIISSNDFPLFNKNRKDAKSSISYQWKNPSELEFDPFNKSHASAVTSMTRTRDVMQLWSLLEACLQSNLMKRAFSILESLYLVPEHKQRFIEDYNMYLNSFSKNDPNFPILKMNEKLTNDLETSFKDVNYNDKTLAIMIHHALNFHSTTSSMLLKPIISAYLKMSVNGIREIFSCLDILTISDLNILMNDLKVITPSQLPNSVRPILESLTLSPTPVNNIENEEGLNKVEAENDSKLHKASNASSDSIKKPSLDPLREVSFHGSTEVLSKDAEKLIAVDTIGMRVIRHTLLGLSLTPEQKEQISKFKFDANDNVLKMKPTKNDDNNNSINFFEIYNSLPTLEEKKAFESALNIFNQDRQKVLENRATEAARERWKHDFEEAKARGDISIEKNLNVKLWKWYNEMLPLVKEEINHCRSLLSEKLSDKKGLNKVDTNRLGYGPYLTLIDPGKMCVITILELLKLNSTGGVIEGMRTARAVISVGKAIEMEFRSEQVLKSESQAFRDVNKKSPEFKKLVQNAKSVFRSSQIEQSKILWPQSIRARIGSVLISMLIQVAKVSVQGVDPVTKAKVHGEAPAFAHGYQYHNGSKLGVLKIHKTLIRQLNGERLIASVQPQLLPMLVEPKPWVNWRSGGYHYTQSTLLRTKDSPEQVAYLKAASDNGDIDRVYDGLNVLGRTPWTVNRKVFDVVSQVWNKGEGFLDIPGAQDEMVLPPAPPKNSDPSILRAWKLQVKTIANKFSSDRSNRCDTNYKLEIARAFLGEKLYFPHNLDFRGRAYPLSPHFNHLGNDMSRGLLIFWHGKKLGPSGLKWLKIHLSNLFGFDKLPLKDRVAFTESHLQDIKDSAENPLTGDRWWTTADKPWQALATCFELNEVMKMDNPEEFISHQPVHQDGTCNGLQHYAALGGDVEGATQVNLVPSDKPQDVYAHVARLVQKRLEIAAEKGDENAKILKDKITRKVVKQTVMTNVYGVTYVGATFQIAKQLSPIFDDRKESLDFSKYLTKHVFSAIRELFHSAHLIQDWLGESAKRISKSIRLDVDEKSFKNGNKPDFMSSVIWTTPLGLPIVQPYREESKKQVETNLQTVFISDPFAVNPVNARRQKAGLPPNFIHSLDASHMLLSAAECGKQGLDFASVHDSYWTHASDIDTMNVVLREQFIKLHEVDLVLRLKEEFDQRYKNYVKIGKLKRSTDLAQKIIRIRKDLSRKLGRSTTLADEIYFEKKRQELLNSPLIEDRNVGEKMVTTVSLFEDITDLDALELENGGDENSGMSVLLPLRLPEIPPKGDFDVTVLRNSQYFFS
SIO_010081: YFL036W
subclass of: SO_0000673
so part of: YFL036W
location: 58782..62837
location: region:58782-62837:1
so has part: feature:58782-62837:1:exon

NP_116617.1
type: Protein
SIO_000068: ncbiprotein

S000001858
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:58782-62837:1:exon

YFL034C-B
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YFL035C
alternative label: YFL035C-A
gene: MOB2
locus tag: YFL034C-B
gene synonym: YFL035C; YFL035C-A
so part of: sequence
location: complement(<63016..>63993)
location: region:63016-63993:-1
so has part: feature:63016-63993:-1:exon
subclass of: SO_0000010

850508
type: Gene
SIO_000068: ncbigene

position:63016:-1
position: 63016
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:63993:-1
position: 63993
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:63016-63993:-1:exon

YFL034C-B
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YFL035C
alternative label: YFL035C-A
gene: MOB2
locus tag: YFL034C-B
gene synonym: YFL035C; YFL035C-A
product: Mob2p
transcript id: NM_001179931.1
SIO_010081: YFL034C-B
subclass of: SO_0000673
so part of: YFL034C-B
location: complement(join(<63016..63859,63974..>63993))
location: region:63016-63993:-1
so has part: feature:63974-63993:-1:exon
so has part: feature:63016-63859:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:63974-63993:-1:exon

position:63974:-1
position: 63974
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:63016-63859:-1:exon

position:63859:-1
position: 63859
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YFL034C-B
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YFL035C
alternative label: YFL035C-A
gene: MOB2
locus tag: YFL034C-B
gene synonym: YFL035C; YFL035C-A
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:11747810|PMID:12196508]
experiment: EXISTENCE:direct assay:GO:0005933 cellular bud [PMID:12196508]
experiment: EXISTENCE:direct assay:GO:0005934 cellular bud tip [PMID:11747810]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:11747810|PMID:12196508]
experiment: EXISTENCE:direct assay:GO:0030295 protein kinase activator activity [PMID:12196508]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:11747810]
experiment: EXISTENCE:genetic interaction:GO:0007118 budding cell apical bud growth [PMID:12972564]
experiment: EXISTENCE:mutant phenotype:GO:0000920 septum digestion after cytokinesis [PMID:11747810|PMID:12196508]
experiment: EXISTENCE:mutant phenotype:GO:0001934 positive regulation of protein phosphorylation [PMID:12196508]
experiment: EXISTENCE:mutant phenotype:GO:0007118 budding cell apical bud growth [PMID:12972564]
experiment: EXISTENCE:mutant phenotype:GO:0007163 establishment or maintenance of cell polarity [PMID:12196508]
note: Activator of Cbk1p kinase; component of the RAM signaling network that regulates cellular polarity and morphogenesis; activation of Cbk1p facilitates the Ace2p-dependent daughter cell-specific transcription of genes involved in cell separation; similar to Mob1p
codon start: 1
product: Mob2p
translation: MSFFNFKAFGRNSKKNKNQPLNVAQPPAMNTIYSSPHSSNSRLSLRNKHHSPKRHSQTSFPAQKSTPQSQQLTSTTPQSQQQEASERSESQQIMFLSEPFVRTALVKGSFKTIVQLPKYVDLGEWIALNVFEFFTNLNQFYGVVAEYVTPDAYPTMNAGPHTDYLWLDANNRQVSLPASQYIDLALTWINNKVNDKNLFPTKNGLPFPQQFSRDVQRIMVQMFRIFAHIYHHHFDKIVHLSLEAHWNSFFSHFISFAKEFKIIDRKEMAPLLPLIESFEKQGKIIYN
SIO_010081: YFL034C-B
subclass of: SO_0000673
so part of: YFL034C-B
location: complement(join(63016..63859,63974..63993))
location: region:63016-63993:-1
so has part: feature:63974-63993:-1:exon
so has part: feature:63016-63859:-1:exon

NP_116618.1
type: Protein
SIO_000068: ncbiprotein

S000001859
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:63974-63993:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:63016-63859:-1:exon

YFL034C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YFL035C-B
gene: RPL22B
locus tag: YFL034C-A
gene synonym: YFL035C-B
so part of: sequence
location: complement(<64243..>64932)
location: region:64243-64932:-1
so has part: feature:64243-64932:-1:exon
subclass of: SO_0000010

850509
type: Gene
SIO_000068: ncbigene

position:64243:-1
position: 64243
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:64932:-1
position: 64932
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:64243-64932:-1:exon

YFL034C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YFL035C-B
gene: RPL22B
locus tag: YFL034C-A
gene synonym: YFL035C-B
product: ribosomal 60S subunit protein L22B
transcript id: NM_001184310.1
SIO_010081: YFL034C-A
subclass of: SO_0000673
so part of: YFL034C-A
location: complement(join(<64243..64599,64921..>64932))
location: region:64243-64932:-1
so has part: feature:64921-64932:-1:exon
so has part: feature:64243-64599:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:64921-64932:-1:exon

position:64921:-1
position: 64921
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:64243-64599:-1:exon

position:64599:-1
position: 64599
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YFL034C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YFL035C-B
gene: RPL22B
locus tag: YFL034C-A
gene synonym: YFL035C-B
experiment: EXISTENCE:direct assay:GO:0002181 cytoplasmic translation [PMID:6814480]
experiment: EXISTENCE:direct assay:GO:0003735 structural constituent of ribosome [PMID:6814480]
experiment: EXISTENCE:direct assay:GO:0022625 cytosolic large ribosomal subunit [PMID:6814480]
experiment: EXISTENCE:genetic interaction:GO:0002181 cytoplasmic translation [PMID:27478489]
note: Ribosomal 60S subunit protein L22A; required for translation of long 5' UTR of IME1 mRNA and meiotic entry; autoregulates splicing of its pre-m-RNA; homologous to mammalian ribosomal protein L22, no bacterial homolog; RPL22B has a paralog, RPL22A, that arose from the whole genome duplication
codon start: 1
product: ribosomal 60S subunit protein L22B
translation: MAPNTSRKQKVIKTLTVDVSSPTENGVFDPASYSKYLIDHIKVDGAVGNLGNAIEVTEDGSIVTVVSSAKFSGKYLKYLTKKYLKKNQLRDWIRFVSIRQNQYKLVFYQVTPEDADEEEDDE
SIO_010081: YFL034C-A
subclass of: SO_0000673
so part of: YFL034C-A
location: complement(join(64243..64599,64921..64932))
location: region:64243-64932:-1
so has part: feature:64921-64932:-1:exon
so has part: feature:64243-64599:-1:exon

NP_116619.1
type: Protein
SIO_000068: ncbiprotein

S000006436
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:64921-64932:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:64243-64599:-1:exon

YFL034W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MIL1
locus tag: YFL034W
so part of: sequence
location: <65477..>68698
location: region:65477-68698:1
so has part: feature:65477-68698:1:exon
subclass of: SO_0000010

850510
type: Gene
SIO_000068: ncbigene

position:65477:1
position: 65477
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:68698:1
position: 68698
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:65477-68698:1:exon

YFL034W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MIL1
locus tag: YFL034W
product: Mil1p
transcript id: NM_001179932.2
SIO_010081: YFL034W
subclass of: SO_0000673
so part of: YFL034W
location: <65477..>68698
location: region:65477-68698:1
so has part: feature:65477-68698:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:65477-68698:1:exon

YFL034W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MIL1
locus tag: YFL034W
experiment: EXISTENCE:direct assay:GO:0016020 membrane [PMID:26658609]
experiment: EXISTENCE:direct assay:GO:0035650 AP-1 adaptor complex binding [PMID:26658609]
experiment: EXISTENCE:mutant phenotype:GO:0035652 clathrin-coated vesicle cargo loading [PMID:26658609]
note: Predicted lipase; binds variant medium clathrin chain Apm2p and contributes to its membrane recruitment; putative integral membrane protein that interacts with Rpp0p component of ribosomal stalk
codon start: 1
product: Mil1p
translation: MSDSEEDLGVQLKGLKIARHLKESGEHTDEESNSSPEHDCGLSNQDDLTVMHTQAKEEVFKRREEDGTRTEDALHEGEAGKEGTGFPSSQSVCSPNEADSGIDRADKPILLDPFKSVHDTDPVPGTKSRSNSDSDSDSDDGGWQEMPAVSSFNIYNHRGELELTSKVRNSEQASETSPTVPPGKNCKSVNDSRFDYTKMAAEQQAQRSYRTNKKTDFLFDHKVLKKKINSSQTSVNLTSSPSTTSLNNEKNNDDDDDDSYDEYEDDVEPVNDLNRDSQLNITKNLLSDMEKFAYVGAINILANQMCTNLATLCLCIDIKSHKKLAHRLQFTQKDMAAWKTVVLSRLYDHLGISQEEIVMIEKLSLHKIQLEDLCKCLKTTQSIDNPWENDRDHEEDGIEETTERMSPNEQNGSVQASTPDPEQSATPETPKAKQSPLSSDVPGKVLDPENVKSQDKLNIDVAWTIICDLFLICLQSSTYDSRSRTLLINFAKVLNMTSLEICEFERRVTDSLDMEQSTEDQVWDEQDHMRNRRRSKRRKKMAYVALAMVGGSLVLGLSGGLLAPVIGGGIAAGLSTIGITGATSFLTGVGGTTVVAVSSTAIGANIGARGMSKRMGSVRTFEFRPLHNNRRVNLILTVSGWMVGNEDDVRLPFSTVDPVEGDLYSLYWEPEMLKSIGQTVSIVATEIFTTSLQQILGATVLTALISSIQWPMALSKLGYILDNPWNVSLDRAWSAGKILADTLIARNLGARPITLVGFSIGARVIFSCLIELCKKKALGLIENVYLFGTPAVMKKEQLVMARSVVSGRFVNGYSDKDWFLAYLFRAAAGGFSAVMGISTIENVEGIENINCTEFVDGHLNYRKSMPKLLKRIGIAVLSEEFVEIEEMMNPEEVKRKRKLINDVDAAQKKLSERKKHNSWVPKWLKPKKSKWKVMVEEAVEEGRDMQDLPENDVNNNENENPDEHEGIARQKRRDAALVDHGALMHELQLIKQAMHEDEIKNKACLPGEDKEVESSNDFLGESHYKPPSTPKINPPQSPNNFQLLSAGRTILPEDDDFDPRGKKKVEFSFPDDI
SIO_010081: YFL034W
subclass of: SO_0000673
so part of: YFL034W
location: 65477..68698
location: region:65477-68698:1
so has part: feature:65477-68698:1:exon

NP_116583.2
type: Protein
SIO_000068: ncbiprotein

S000001860
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:65477-68698:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS603; Highly-efficient autonomously replicating sequence on Chromosome VI; activated during the second half of S phase in 67% of cell cycles
so part of: sequence
location: 68759..68861
location: region:68759-68861:1
so has part: feature:68759-68861:1:region

S000007635
type: SGD
SIO_000068: sgd

position:68759:1
position: 68759
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:68861:1
position: 68861
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:68759-68861:1:region

YFL033C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: TAK1
gene: RIM15
locus tag: YFL033C
gene synonym: TAK1
so part of: sequence
location: complement(<69115..>74427)
location: region:69115-74427:-1
so has part: feature:69115-74427:-1:exon
subclass of: SO_0000010

850511
type: Gene
SIO_000068: ncbigene

position:69115:-1
position: 69115
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:74427:-1
position: 74427
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:69115-74427:-1:exon

YFL033C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: TAK1
gene: RIM15
locus tag: YFL033C
gene synonym: TAK1
product: protein kinase RIM15
transcript id: NM_001179933.1
SIO_010081: YFL033C
subclass of: SO_0000673
so part of: YFL033C
location: complement(<69115..>74427)
location: region:69115-74427:-1
so has part: feature:69115-74427:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:69115-74427:-1:exon

YFL033C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: TAK1
gene: RIM15
locus tag: YFL033C
gene synonym: TAK1
EC number: 2.7.11.1
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:9744870|PMID:9111339|PMID:24140345|PMID:16319894]
experiment: EXISTENCE:direct assay:GO:0004674 protein serine/threonine kinase activity [PMID:20471941|PMID:23273919]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14690612]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14690612|PMID:14562095]
experiment: EXISTENCE:genetic interaction:GO:0010508 positive regulation of autophagy [PMID:25660547]
experiment: EXISTENCE:genetic interaction:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:24140345]
experiment: EXISTENCE:genetic interaction:GO:0061408 positive regulation of transcription from RNA polymerase II promoter in response to heat stress [PMID:24140345]
experiment: EXISTENCE:genetic interaction:GO:1903452 positive regulation of G1 to G0 transition [PMID:23273919]
experiment: EXISTENCE:mutant phenotype:GO:0004674 protein serine/threonine kinase activity [PMID:20471941]
experiment: EXISTENCE:mutant phenotype:GO:0010508 positive regulation of autophagy [PMID:25660547]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:24140345]
experiment: EXISTENCE:mutant phenotype:GO:0051039 positive regulation of transcription involved in meiotic cell cycle [PMID:9111339]
experiment: EXISTENCE:mutant phenotype:GO:0061408 positive regulation of transcription from RNA polymerase II promoter in response to heat stress [PMID:24140345]
experiment: EXISTENCE:mutant phenotype:GO:1901992 positive regulation of mitotic cell cycle phase transition [PMID:23861665]
experiment: EXISTENCE:mutant phenotype:GO:1903452 positive regulation of G1 to G0 transition [PMID:20471941|PMID:9744870]
note: Protein kinase involved in cell proliferation in response to nutrients; glucose-repressible; involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; phosphorylates Igo1p and Igo2p; substrate of Pho80p-Pho85p kinase
codon start: 1
product: protein kinase RIM15
translation: MFNRSNTAGGSQAMKEGLGINKLSPISSNSNPSSLTSSNYEKYLQLATEKNPCMILELELDGKVRYGSPQWNTITGVADDSGSSPTYIADLILGSDQDKGVFQKATDMLLMNDDTSCTITFKIKAADYEGSAGCDDESTITTLEARGILIRDGHTQLPSHTMWIVKPRTNDWSDFYANEDAQDDMVIQLSDNCDDIDIQLPEEFAKTLGFGAKIFVQYLKRIRLEMIIDEFNLPLPKMELCRVCENFVPVWWLETHSQSCVCEHRTESLIQLLHDNLLEQQAILANFTKDSEYKGSQIQVRSNNFLNQVLDSLRELCQDAIDINPSEMVPDLYHSLSTFPQDNGNNNNNNNNNNNNNNALLDQFPIQKDTVSLNSYFQFSPRTNHNIQNVTSWQSRFFLNDDQDPGLALLIHDTLDLARKKVDAVLRLDNAMTYSLKIKNEVNNYVVQLIREQIEINKHAILTHPMNLRSSSIFHSPLPQIHSQQPEAENLIYSSSTPLQVQHDQCASFEAPSKSHLEPIPFPVSSIEETPTANDIRHPSPLPRSCSNTVMKLPTPRRKLDSNGLFSDAYLNADIIPNPSIESTISIDRDNNTNSRGSSMKQYGIGEATDSRTSNSERPSSSSSRLGIRSRSITPRQKIEYSHVDNDDRTNEMLSRDKDSLQPQPSVDTTITSSTQATTTGTKTNSNNSTNSVLPKLMTSISLTPRRGSPSFGNLASHSMQQTNSFKLIHDKSPISSPFTFSKDFLTPEQHPSNIARTDSINNAMLTSPNMPLSPLLLATNQTVKSPTPSIKDYDILKPISKGAYGSVYLARKKLTGDYFAIKVLRKSDMIAKNQVTNVKSERAIMMVQSDKPYVARLFASFQNKDNLFLVMEYLPGGDLATLIKMMGYLPDQWAKQYLTEIVVGVNDMHQNGIIHHDLKPENLLIDNAGHVKLTDFGLSRAGLIRRHKFVPHKSSLSISSTLPIDNPANNFTMNNNNSNHSQLSTPDSFTSDHKQYNRSKKSSLGQQYEHSEYSSTSNSHSMTPTPSTNTVVYPSYYRGKDRSHGSSNIDLPASLRRSESQLSFSLLDISRSSTPPLANPTNSNANNIMRRKSLTENKSFSNDLLSSDAIAATNTNINSNNNISLSPAPSDLALFYPDDSKQNKKFFGTPDYLAPETIEGKGEDNKQCDWWSVGCIFFELLLGYPPFHAETPDAVFKKILSGVIQWPEFKNEEEEREFLTPEAKDLIEKLLVVDPAKRLGAKGIQEIKDHPYFKNVDWDHVYDEEASFVPTIDNPEDTDYFDLRGAELQDFGDDIENDNANILFGKHGINTDVSELSAANLSPPLNHKNILSRKLSMSNTTNRSSNNSNSSVHDFGAHTPVNKLSIASVLESVPQETGYITPNGTGTTTTSAKNSPNLKNLSLAIPPHMRDRRSSKLNDSQTEFGSFNFRNLSALDKANKDAINRLKSEHFSEQPGVHRRTSSASLMGSSSDGSVSTPGSNASNTTSGGKLKIHKPTISGSPSTFGTFPKTFLRSDSFSTRSYSPERSISIDSSTLSRKGSIIGDNQQTTANSSDSPTMTKFKSPLSPANTTTVSSYFSRQRVLSKSFSQRTNSSDLSAEESDRLQAISRVNSLRNRRRSGRKSSSTSEIGYHMDVLVCEPIPIHRYRVTKDLENLGCTVVSVGAGDELVSRATSGVSFDLIMTALKLPKLGAIDIVQLLKQTNGANSTTPIVAITNYFQEAATSRVFDDVLEKPVKLDELKKLVAKYALKKSQEDEEHTILSDSDETH
SIO_010081: YFL033C
subclass of: SO_0000673
so part of: YFL033C
location: complement(69115..74427)
location: region:69115-74427:-1
so has part: feature:69115-74427:-1:exon

NP_116620.1
type: Protein
SIO_000068: ncbiprotein

S000001861
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:69115-74427:-1:exon

YFL031W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ERN4
alternative label: IRE15
gene: HAC1
locus tag: YFL031W
gene synonym: ERN4; IRE15
so part of: sequence
location: <75179..>76147
location: region:75179-76147:1
so has part: feature:75179-76147:1:exon
subclass of: SO_0000010

850513
type: Gene
SIO_000068: ncbigene

position:75179:1
position: 75179
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:76147:1
position: 76147
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:75179-76147:1:exon

YFL031W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ERN4
alternative label: IRE15
gene: HAC1
locus tag: YFL031W
gene synonym: ERN4; IRE15
product: transcription factor HAC1
transcript id: NM_001179935.1
SIO_010081: YFL031W
subclass of: SO_0000673
so part of: YFL031W
location: join(<75179..75839,76092..>76147)
location: region:75179-76147:1
so has part: feature:75179-75839:1:exon
so has part: feature:76092-76147:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:75179-75839:1:exon

position:75839:1
position: 75839
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:76092-76147:1:exon

position:76092:1
position: 76092
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YFL031W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ERN4
alternative label: IRE15
gene: HAC1
locus tag: YFL031W
gene synonym: ERN4; IRE15
experiment: EXISTENCE:direct assay:GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific [PMID:15141165|PMID:9077435]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:8898193]
experiment: EXISTENCE:direct assay:GO:0010674 negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle [PMID:15141165]
experiment: EXISTENCE:direct assay:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:9077435]
experiment: EXISTENCE:mutant phenotype:GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific [PMID:15141165|PMID:9077435]
experiment: EXISTENCE:mutant phenotype:GO:0010674 negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle [PMID:15141165]
experiment: EXISTENCE:mutant phenotype:GO:0030968 endoplasmic reticulum unfolded protein response [PMID:16582425]
experiment: EXISTENCE:mutant phenotype:GO:0034976 response to endoplasmic reticulum stress [PMID:26966233]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:9077435|PMID:8898193]
note: Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog); regulates unfolded protein response via UPRE binding and membrane biogenesis; translation initiation repressed under non-stress conditions by un-spliced intron that interacts with 5'-UTR; under ER stress Ire1p nuclease cleaves out inhibitory intron and triggers efficient Hac1p translation; two functional forms of Hac1p are produced; protein abundance increases in response to DNA replication stress
codon start: 1
product: transcription factor HAC1
translation: MEMTDFELTSNSQSNLAIPTNFKSTLPPRKRAKTKEEKEQRRIERILRNRRAAHQSREKKRLHLQYLERKCSLLENLLNSVNLEKLADHEDALTCSHDAFVASLDEYRDFQSTRGASLDTRASSHSSSDTFTPSPLNCTMEPATLSPKSMRDSASDQETSWELQMFKTENVPESTTLPAVDNNNLFDAVASPLADPLCDDIAGNSLPFDNSIDLDNWRNPEAQSGLNSFELNDFFITS
SIO_010081: YFL031W
subclass of: SO_0000673
so part of: YFL031W
location: join(75179..75839,76092..76147)
location: region:75179-76147:1
so has part: feature:75179-75839:1:exon
so has part: feature:76092-76147:1:exon

NP_116622.1
type: Protein
SIO_000068: ncbiprotein

S000001863
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:75179-75839:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:76092-76147:1:exon

YFL030W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: AGX1
locus tag: YFL030W
so part of: sequence
location: <76831..>77988
location: region:76831-77988:1
so has part: feature:76831-77988:1:exon
subclass of: SO_0000010

850514
type: Gene
SIO_000068: ncbigene

position:76831:1
position: 76831
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:77988:1
position: 77988
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:76831-77988:1:exon

YFL030W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: AGX1
locus tag: YFL030W
product: alanine--glyoxylate transaminase
transcript id: NM_001179936.1
SIO_010081: YFL030W
subclass of: SO_0000673
so part of: YFL030W
location: <76831..>77988
location: region:76831-77988:1
so has part: feature:76831-77988:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:76831-77988:1:exon

YFL030W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: AGX1
locus tag: YFL030W
EC number: 2.6.1.44
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0008453 alanine-glyoxylate transaminase activity [PMID:16226833]
experiment: EXISTENCE:direct assay:GO:0019265 glycine biosynthetic process, by transamination of glyoxylate [PMID:16226833]
experiment: EXISTENCE:mutant phenotype:GO:0008453 alanine-glyoxylate transaminase activity [PMID:14745783]
note: Alanine:glyoxylate aminotransferase (AGT); catalyzes the synthesis of glycine from glyoxylate, which is one of three pathways for glycine biosynthesis in yeast; similar to mammalian and plant alanine:glyoxylate aminotransferases; human homolog AGXT complements yeast null mutant
codon start: 1
product: alanine--glyoxylate transaminase
translation: MTKSVDTLLIPGPIILSGAVQKALDVPSLGHTSPEFVSIFQRVLKNTRAVFKSAAASKSQPFVLAGSGTLGWDIFASNFILSKAPNKNVLVVSTGTFSDRFADCLRSYGAQVDVVRPLKIGESVPLELITEKLSQNSYGAVTVTHVDTSTAVLSDLKAISQAIKQTSPETFFVVDAVCSIGCEEFEFDEWGVDFALTASQKAIGAPAGLSISLCSSRFMDYALNDSKNGHVHGYFSSLRRWTPIMENYEAGKGAYFATPPVQLINSLDVALKEILEEGLHKRWDLHREMSDWFKDSLVNGLQLTSVSRYPSNMSAHGLTAVYVADPPDVIAFLKSHGVVIAGGIHKDIGPKYIRIGHMGVTACNKNLPYMKNCFDLIKLALQRKK
SIO_010081: YFL030W
subclass of: SO_0000673
so part of: YFL030W
location: 76831..77988
location: region:76831-77988:1
so has part: feature:76831-77988:1:exon

NP_116623.1
type: Protein
SIO_000068: ncbiprotein

S000001864
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:76831-77988:1:exon

YFL029C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CIV1
gene: CAK1
locus tag: YFL029C
gene synonym: CIV1
so part of: sequence
location: complement(<78055..>79161)
location: region:78055-79161:-1
so has part: feature:78055-79161:-1:exon
subclass of: SO_0000010

850515
type: Gene
SIO_000068: ncbigene

position:78055:-1
position: 78055
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:79161:-1
position: 79161
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:78055-79161:-1:exon

YFL029C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CIV1
gene: CAK1
locus tag: YFL029C
gene synonym: CIV1
product: cyclin-dependent protein kinase-activating kinase CAK1
transcript id: NM_001179937.1
SIO_010081: YFL029C
subclass of: SO_0000673
so part of: YFL029C
location: complement(<78055..>79161)
location: region:78055-79161:-1
so has part: feature:78055-79161:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:78055-79161:-1:exon

YFL029C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CIV1
gene: CAK1
locus tag: YFL029C
gene synonym: CIV1
EC number: 2.7.11.22
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:9819350]
experiment: EXISTENCE:direct assay:GO:0019912 cyclin-dependent protein kinase activating kinase activity [PMID:10373527|PMID:8752210|PMID:8752211|PMID:8781234]
experiment: EXISTENCE:genetic interaction:GO:0060633 negative regulation of transcription initiation by RNA polymerase II [PMID:19269370]
experiment: EXISTENCE:mutant phenotype:GO:0000086 G2/M transition of mitotic cell cycle [PMID:8752210|PMID:8752211]
experiment: EXISTENCE:mutant phenotype:GO:0019912 cyclin-dependent protein kinase activating kinase activity [PMID:10373527|PMID:8752210|PMID:8752211|PMID:8781234]
experiment: EXISTENCE:mutant phenotype:GO:0051321 meiotic cell cycle [PMID:11739722]
note: Cyclin-dependent kinase-activating kinase; required for passage through the cell cycle; phosphorylates and activates Cdc28p; nucleotide-binding pocket differs significantly from those of most other protein kinases; required for premeiotic DNA synthesis, expression of early and middle sporulation specific genes and direct phosphorylation of the Smk1p MAPK to regulate spore morphogenesis
codon start: 1
product: cyclin-dependent protein kinase-activating kinase CAK1
translation: MKLDSIDITHCQLVKSTRTARIYRSDTYAIKCLALDFDIPPHNAKFEVSILNKLGNKCKHILPLLESKATDNNDLLLLFPFEEMNLYEFMQMHYKRDRRKKNPYYDLLNPSIPIVADPPVQKYTNQLDVNRYSLSFFRQMVEGIAFLHENKIIHRDIKPQNIMLTNNTSTVSPKLYIIDFGISYDMANNSQTSAEPMDSKVTDISTGIYKAPEVLFGVKCYDGGVDVWSLLIIISQWFQRETSRMGHVPAMIDDGSDDMNSDGSDFRLICSIFEKLGIPSIQKWEEVAQHGSVDAFVGMFGADGDGKYVLDQEKDVQISIVERNMPRLDEIADVKVKQKFINCILGMVSFSPNERWSCQRILQELEKP
SIO_010081: YFL029C
subclass of: SO_0000673
so part of: YFL029C
location: complement(78055..79161)
location: region:78055-79161:-1
so has part: feature:78055-79161:-1:exon

NP_116624.1
type: Protein
SIO_000068: ncbiprotein

S000001865
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:78055-79161:-1:exon

YFL028C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CAF16
locus tag: YFL028C
so part of: sequence
location: complement(<79344..>80213)
location: region:79344-80213:-1
so has part: feature:79344-80213:-1:exon
subclass of: SO_0000010

850516
type: Gene
SIO_000068: ncbigene

position:79344:-1
position: 79344
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:80213:-1
position: 80213
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:79344-80213:-1:exon

YFL028C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CAF16
locus tag: YFL028C
product: putative ATP-binding cassette family ATPase CAF16
transcript id: NM_001179938.1
SIO_010081: YFL028C
subclass of: SO_0000673
so part of: YFL028C
location: complement(<79344..>80213)
location: region:79344-80213:-1
so has part: feature:79344-80213:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:79344-80213:-1:exon

YFL028C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CAF16
locus tag: YFL028C
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0030014 CCR4-NOT complex [PMID:11113136]
experiment: EXISTENCE:mutant phenotype:GO:0006357 regulation of transcription by RNA polymerase II [PMID:11113136]
note: Part of evolutionarily-conserved CCR4-NOT regulatory complex; contains single ABC-type ATPase domain but no transmembrane domain; interacts with several subunits of Mediator
codon start: 1
product: putative ATP-binding cassette family ATPase CAF16
translation: MVSQFAIEVRNLTYKFKESSDPSVVDINLQIPWNTRSLVVGANGAGKSTLLKLLSGKHLCLDGKILVNGLDPFSPLSMNQVDDDESVEDSTNYQTTTYLGTEWCHMSIINRDIGVLELLKSIGFDHFRERGERLVRILDIDVRWRMHRLSDGQKRRVQLAMGLLKPWRVLLLDEVTVDLDVIARARLLEFLKWETETRRCSVVYATHIFDGLAKWPNQVYHMKSGKIVDNLDYQKDVEFSEVVNAKVNGQVAFENDNNKVVISKVNSLHPLALEWLKRDNQIPDKEIGI
SIO_010081: YFL028C
subclass of: SO_0000673
so part of: YFL028C
location: complement(79344..80213)
location: region:79344-80213:-1
so has part: feature:79344-80213:-1:exon

NP_116625.1
type: Protein
SIO_000068: ncbiprotein

S000001866
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:79344-80213:-1:exon

YFL027C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GYP8
locus tag: YFL027C
so part of: sequence
location: complement(<80419..>81912)
location: region:80419-81912:-1
so has part: feature:80419-81912:-1:exon
subclass of: SO_0000010

850517
type: Gene
SIO_000068: ncbigene

position:80419:-1
position: 80419
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:81912:-1
position: 81912
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:80419-81912:-1:exon

YFL027C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GYP8
locus tag: YFL027C
product: GTPase-activating protein GYP8
transcript id: NM_001179939.1
SIO_010081: YFL027C
subclass of: SO_0000673
so part of: YFL027C
location: complement(<80419..>81912)
location: region:80419-81912:-1
so has part: feature:80419-81912:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:80419-81912:-1:exon

YFL027C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GYP8
locus tag: YFL027C
experiment: EXISTENCE:direct assay:GO:0005096 GTPase activator activity [PMID:12189143]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:12189143]
experiment: EXISTENCE:direct assay:GO:0005777 peroxisome [PMID:36164978]
experiment: EXISTENCE:mutant phenotype:GO:0016192 vesicle-mediated transport [PMID:12189143]
note: GTPase-activating protein for yeast Rab family members; Ypt1p is the preferred in vitro substrate but also acts on Sec4p, Ypt31p and Ypt32p; involved in the regulation of ER to Golgi vesicle transport; localizes to the ER and peroxisomes
codon start: 1
product: GTPase-activating protein GYP8
translation: MPLRSLFHTNQSSHDKDALTRGGYNAYLESLSRCDSGKAEEQKGKVISKLLEKKDVRALRYIGLGPLGFVNNSLRKDCWYELLASQLLIDDATEYITPVEKHKDEGQVILDAERSFGGIVDKNLKLQLRKLLVELITRVLRKYPTLNYYQGYHDIVSVFIMCFSWNVTKENGLELENLSLQEEIDMERLFYCIEAFTLLYLRDFMMNSLDFSFEQLRVISSLIKESNMKFYNLFKFDENEPLFAIGSILTIFAHNLKPIDSGDNNLHKILFQIFDMTISMQSMRLPLIIYKNLLLQNASEISKQIEANSDFFENDFDLRHGAIQTVLQKKLYDEALWEEVLQITRKDATTASKKALKRVSLNKYSALLNTACGKPGCFDMSTIIFYLSEQTKMNEHYKEEKYHGVAARSKTRALVQRLGHFLPSKYNRWSKISLLIGIVAILYQLRTTRSLSLVLNLRYMISTKLKDLSHININLHHVSHIWVDPIRDILKLGHPTR
SIO_010081: YFL027C
subclass of: SO_0000673
so part of: YFL027C
location: complement(80419..81912)
location: region:80419-81912:-1
so has part: feature:80419-81912:-1:exon

NP_444296.1
type: Protein
SIO_000068: ncbiprotein

S000001867
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:80419-81912:-1:exon

YFL026W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: STE2
locus tag: YFL026W
so part of: sequence
location: <82580..>83875
location: region:82580-83875:1
so has part: feature:82580-83875:1:exon
subclass of: SO_0000010

850518
type: Gene
SIO_000068: ncbigene

position:82580:1
position: 82580
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:83875:1
position: 83875
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:82580-83875:1:exon

YFL026W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: STE2
locus tag: YFL026W
product: alpha-factor pheromone receptor STE2
transcript id: NM_001179940.2
SIO_010081: YFL026W
subclass of: SO_0000673
so part of: YFL026W
location: <82580..>83875
location: region:82580-83875:1
so has part: feature:82580-83875:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:82580-83875:1:exon

YFL026W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: STE2
locus tag: YFL026W
experiment: EXISTENCE:direct assay:GO:0000755 cytogamy [PMID:17369365]
experiment: EXISTENCE:direct assay:GO:0004934 mating-type alpha-factor pheromone receptor activity [PMID:2161538]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:2839507]
experiment: EXISTENCE:genetic interaction:GO:0004934 mating-type alpha-factor pheromone receptor activity [PMID:9742115]
experiment: EXISTENCE:mutant phenotype:GO:0000750 pheromone-dependent signal transduction involved in conjugation with cellular fusion [PMID:3037311]
experiment: EXISTENCE:mutant phenotype:GO:0000755 cytogamy [PMID:17369365]
experiment: EXISTENCE:mutant phenotype:GO:0004934 mating-type alpha-factor pheromone receptor activity [PMID:6360378|PMID:9742115]
experiment: EXISTENCE:mutant phenotype:GO:0030031 cell projection assembly [PMID:12378535]
note: Receptor for alpha-factor pheromone; seven transmembrane-domain GPCR that interacts with both pheromone and a heterotrimeric G protein to initiate the signaling response that leads to mating between haploid a and alpha cells
codon start: 1
product: alpha-factor pheromone receptor STE2
translation: MSDAAPSLSNLFYDPTYNPGQSTINYTSIYGNGSTITFDELQGLVNSTVTQAIMFGVRCGAAALTLIVMWMTSRSRKTPIFIINQVSLFLIILHSALYFKYLLSNYSSVTYALTGFPQFISRGDVHVYGATNIIQVLLVASIETSLVFQIKVIFTGDNFKRIGLMLTSISFTLGIATVTMYFVSAVKGMIVTYNDVSATQDKYFNASTILLASSINFMSFVLVVKLILAIRSRRFLGLKQFDSFHILLIMSCQSLLVPSIIFILAYSLKPNQGTDVLTTVATLLAVLSLPLSSMWATAANNASKTNTITSDFTTSTDRFYPGTLSSFQTDSINNDAKSSLRSRLYDLYPRRKETTSDKHSERTFVSETADDIEKNQFYQLPTPTSSKNTRIGPFADASYKEGEVEPVDMYTPDTAADEEARKFWTEDNNNL
SIO_010081: YFL026W
subclass of: SO_0000673
so part of: YFL026W
location: 82580..83875
location: region:82580-83875:1
so has part: feature:82580-83875:1:exon

NP_116627.2
type: Protein
SIO_000068: ncbiprotein

S000001868
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:82580-83875:1:exon

YFL025C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PER17
gene: BST1
locus tag: YFL025C
gene synonym: PER17
so part of: sequence
location: complement(<84145..>87234)
location: region:84145-87234:-1
so has part: feature:84145-87234:-1:exon
subclass of: SO_0000010

850519
type: Gene
SIO_000068: ncbigene

position:84145:-1
position: 84145
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:87234:-1
position: 87234
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:84145-87234:-1:exon

YFL025C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PER17
gene: BST1
locus tag: YFL025C
gene synonym: PER17
product: Bst1p
transcript id: NM_001179941.1
SIO_010081: YFL025C
subclass of: SO_0000673
so part of: YFL025C
location: complement(<84145..>87234)
location: region:84145-87234:-1
so has part: feature:84145-87234:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:84145-87234:-1:exon

YFL025C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PER17
gene: BST1
locus tag: YFL025C
gene synonym: PER17
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:8862519|PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0006505 GPI anchor metabolic process [PMID:14734546]
experiment: EXISTENCE:genetic interaction:GO:0050185 phosphatidylinositol deacylase activity [PMID:14734546]
experiment: EXISTENCE:mutant phenotype:GO:0006621 protein retention in ER lumen [PMID:8862519]
experiment: EXISTENCE:mutant phenotype:GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport [PMID:8862519]
experiment: EXISTENCE:mutant phenotype:GO:0016050 vesicle organization [PMID:8862519]
experiment: EXISTENCE:mutant phenotype:GO:0030433 ubiquitin-dependent ERAD pathway [PMID:11673477]
experiment: EXISTENCE:mutant phenotype:GO:0034368 protein-lipid complex remodeling [PMID:27325793]
note: GPI inositol deacylase of the endoplasmic reticulum (ER); negatively regulates COPII vesicle formation; prevents production of vesicles with defective subunits; required for proper discrimination between resident ER proteins and Golgi-bound cargo molecules; functional ortholog of human PGAP1, mutation of which is associated with intellectual disability and encephalopathy
codon start: 1
product: Bst1p
translation: MGIRRLVSVITRPIINKVNSSGQYSRVLATREDQDKASPKYMNNDKIAKKPYTYRLFSILGILSICSLLLISLLKPFNGADAPQCESIYMFPSYARIDGFDERYTPLAHKYHLYLYREQSVDREPLNGDELQLDGIPVLFIPGNAGSFRQCRSIASACSNIYFDSNTRATLRNENVRNLDFFTADFNEDFTAFHGETMLDQAEYLNDAIKYILSLYERTPDYPHPKPQSVIIVGHSMGGIVSRVMLTLKNHVPGSISTILTLSSPHAASPVTFDGDILKLYKNTNEYWRKQLSQNDSFFSKNISLVSITGGILDTTLPADYASVEDLVSLENGFTSFTTTIPDVWTPIDHLAIVWCKQLREVLARLLLESIDASKPEKVKPLNQRLQIARKLLLSGFEDYSWMNSKLNYPQENLQEFSDNFFSDYATLEMNDVLDFEMFNLEKWHNNYTKINIPSNISSTEHLHFTLLTSLDMPMIYFCTESRVNLSCITAVDSILTVPRSSKDTQFAADSSFGEAKNPFKAVSVGKNILQKYDYLMISKPTYGEFSEQEGMEDNQGFLLALLRNVSNVQIVNTTPSQILLFGEQLHLDGKDIEQVISFSNLWDSLLSYKLETKIEASNEGIASEETLFQPFIRQWVYEPFESKWHLNIINKSLDINMHNVAPFIPLNESEPRSLQLSFFIPPGMSLEAKMTINWSLTLKMLFIRYRLALASFPVAFIALVLSYQFYWYNKTSEFPSFDSTLGYILRKHGILMFFTLFLASPVVNNKLVQRILYLLDPVGLNYPFLLSERNMHANFYYLGIRDWFMSTIGILFGVMTVGLLALVSKIFGSLEILVIFLQRKLSKKNTEDKEAFDTIEHKAYGKGRLMASVLLLLLVFFHIPYQMAFVISLVIQIATCIRVALLKLSNNEQKLNLLNYNMTLLLLLLFVSAINIPIIIVFLHNVAIKWETSFRSHHNILAVAPIIFLVGNNSIFKMPNSVPLDTWDGKVTIILFVYLTVFSFIYGIRNLYWIHHLVNIICAWLLFFETIH
SIO_010081: YFL025C
subclass of: SO_0000673
so part of: YFL025C
location: complement(84145..87234)
location: region:84145-87234:-1
so has part: feature:84145-87234:-1:exon

NP_116628.1
type: Protein
SIO_000068: ncbiprotein

S000001869
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:84145-87234:-1:exon

YFL024C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: EPL1
locus tag: YFL024C
so part of: sequence
location: complement(<87847..>90345)
location: region:87847-90345:-1
so has part: feature:87847-90345:-1:exon
subclass of: SO_0000010

850520
type: Gene
SIO_000068: ncbigene

position:87847:-1
position: 87847
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:90345:-1
position: 90345
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:87847-90345:-1:exon

YFL024C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: EPL1
locus tag: YFL024C
product: Epl1p
transcript id: NM_001179942.1
SIO_010081: YFL024C
subclass of: SO_0000673
so part of: YFL024C
location: complement(<87847..>90345)
location: region:87847-90345:-1
so has part: feature:87847-90345:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:87847-90345:-1:exon

YFL024C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: EPL1
locus tag: YFL024C
experiment: EXISTENCE:direct assay:GO:0004402 histone acetyltransferase activity [PMID:10911987|PMID:17274630]
experiment: EXISTENCE:direct assay:GO:0006281 DNA repair [PMID:15610740|PMID:16135807]
experiment: EXISTENCE:direct assay:GO:0006357 regulation of transcription by RNA polymerase II [PMID:10911987]
experiment: EXISTENCE:direct assay:GO:0016573 histone acetylation [PMID:10911987]
experiment: EXISTENCE:direct assay:GO:0032777 Piccolo NuA4 histone acetyltransferase complex [PMID:12782659]
experiment: EXISTENCE:direct assay:GO:0035267 NuA4 histone acetyltransferase complex [PMID:10911987|PMID:15485911]
experiment: EXISTENCE:mutant phenotype:GO:0016239 positive regulation of macroautophagy [PMID:22539722]
note: Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex; conserved region at N-terminus is essential for interaction with the NPC (nucleosome core particle); required for autophagy; homologous to Drosophila Enhancer of Polycomb; coding sequence contains length polymorphisms in different strains
codon start: 1
product: Epl1p
translation: MPTPSNAIEINDGSHKSGRSTRRSGSRSAHDDGLDSFSKGDSGAGASAGSSNSRFRHRKISVKQHLKIYLPNDLKHLDKDELQQREVVEIETGVEKNEEKEVHLHRILQMGSGHTKHKDYIPTPDASMTWNEYDKFYTGSFQETTSYIKFSATVEDCCGTNYNMDERDETFLNEQVNKGSSDILTEDEFEILCSSFEHAIHERQPFLSMDPESILSFEELKPTLIKSDMADFNLRNQLNHEINSHKTHFITQFDPVSQMNTRPLIQLIEKFGSKIYDYWRERKIEVNGYEIFPQLKFERPGEKEEIDPYVCFRRREVRHPRKTRRIDILNSQRLRALHQELKNAKDLALLVAKRENVSLNWINDELKIFDQRVKIKNLKRSLNISGEDDDLINHKRKRPTIVTVEQREAELRKAELKRAAAAAAAAKAKNNKRNNQLEDKSSRLTKQQQQQLLQQQQQQQQNALKTENGKQLANASSSSTSQPITSHVYVKLPSSKIPDIVLEDVDALLNSKEKNARKFVQEKMEKRKIEDADVFFNLTDDPFNPVFDMSLPKNFSTSNVPFASIASSKFQIDRSFYSSHLPEYLKGISDDIRIYDSNGRSRNKDNYNLDTKRIKKTELYDPFQENLEIHSREYPIKFRKRVGRSNIKYVDRMPNFTTSSTKSACSLMDFVDFDSIEKEQYSREGSNDTDSINVYDSKYDEFVRLYDKWKYDSPQNEYGIKFSDEPARLNQISNDTQVIRFGTMLGTKSYEQLREATIKYRRDYITRLKQKHIQHLQQQQQQQQQQQQQAQQQKQKSQNNNSNSSNSLKKLNDSLINSEAKQNSSITQKNSS
SIO_010081: YFL024C
subclass of: SO_0000673
so part of: YFL024C
location: complement(87847..90345)
location: region:87847-90345:-1
so has part: feature:87847-90345:-1:exon

NP_116629.1
type: Protein
SIO_000068: ncbiprotein

S000001870
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:87847-90345:-1:exon

YFL023W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: URI1
gene: BUD27
locus tag: YFL023W
gene synonym: URI1
so part of: sequence
location: <90986..>93376
location: region:90986-93376:1
so has part: feature:90986-93376:1:exon
subclass of: SO_0000010

850521
type: Gene
SIO_000068: ncbigene

position:90986:1
position: 90986
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:93376:1
position: 93376
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:90986-93376:1:exon

YFL023W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: URI1
gene: BUD27
locus tag: YFL023W
gene synonym: URI1
product: Bud27p
transcript id: NM_001179943.1
SIO_010081: YFL023W
subclass of: SO_0000673
so part of: YFL023W
location: <90986..>93376
location: region:90986-93376:1
so has part: feature:90986-93376:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:90986-93376:1:exon

YFL023W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: URI1
gene: BUD27
locus tag: YFL023W
gene synonym: URI1
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:18959479]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:19387492|PMID:14562095]
experiment: EXISTENCE:genetic interaction:GO:0001731 formation of translation preinitiation complex [PMID:19387492]
experiment: EXISTENCE:mutant phenotype:GO:0001731 formation of translation preinitiation complex [PMID:19387492]
experiment: EXISTENCE:mutant phenotype:GO:0006364 rRNA processing [PMID:32503921]
experiment: EXISTENCE:mutant phenotype:GO:0042791 5S class rRNA transcription by RNA polymerase III [PMID:32503921]
experiment: EXISTENCE:mutant phenotype:GO:0042797 tRNA transcription by RNA polymerase III [PMID:32503921]
experiment: EXISTENCE:mutant phenotype:GO:1990113 RNA polymerase I assembly [PMID:23459708]
experiment: EXISTENCE:mutant phenotype:GO:1990114 RNA polymerase II core complex assembly [PMID:23459708]
experiment: EXISTENCE:mutant phenotype:GO:1990115 RNA polymerase III assembly [PMID:23459708]
experiment: EXISTENCE:mutant phenotype:GO:2001209 positive regulation of transcription elongation by RNA polymerase I [PMID:32503921]
note: Unconventional prefoldin protein involved in translation initiation; required for correct assembly of RNAP I, II, and III in an Rpb5p-dependent manner; shuttles between nucleus and cytoplasm; mutants have inappropriate expression of nutrient sensitive genes due to translational derepression of Gcn4p transcription factor; diploid mutants show random budding; mutations affect TOR signaling; ortholog of human URI/RMP
codon start: 1
product: Bud27p
translation: MDLLAASVESTLKNLQDKRNFLSEQREHYIDIRSRLVRFINDNDDGEEEGEGQGMVFGDIIISTSKIYLSLGYEYYVEKTKEEAITFVDDKLKLMEDAIEQFNLKIEEAKKTLDNLNHMEDGNGIEEDEANNDEDFLPSMEIREELDDEGNVISSSVTPTTKQPSQSNSKKEQTPAVGPKEKGLAKEKKSKSFEENLKGKLLKRNDEVKKKVQPSKVDTENVYTFADLVQQMDQQDELEDGYIETDEINYDYDAFENSNFKVNDNYEEDDEDEDEEEYLNHSIIPGFEAQSSFLQQIQRLRAQKQSQDHEREEGDVNKSLKPILKKSSFAENSDKKQKKKQVGFASSLEIHEVENLKEENKRQMQSFAVPMYETQESTGIANKMTSDEFDGDLFAKMLGVQEADEVHEKYKEELINQERLEGEASRSNRRTRVSRFRKDRASKKENTLSTFKQETTRSVENEVVEKEPVVGDIIEKEPVVGDVIEKEPVVGDVIEKEPAVTDIVEREPAVNDIVERKPVVGDIIEKEPTINDIVEKEPEINSKSEFETPFKKKKLKSLQKPRSSKSMKKKFDPKILENISDDDYDDDDDGNKKLLSNKSKNNTDEQDKFPSKIQEVSRSMAKTGATVGSEPVRITNVDYHALGGNLDDMVKAYSLGLYDDDLEEDPGTIVEKLEDFKEYNKQVELLRDEIRDFQLENKPVTMEEEENDGNVMNDIIEHEFPESYTNDEDEVALHPGRLQEEVAIEYRRLKEATASKWQSSSPAAHTEGELEPIDKFGNPVKTSRFRSQRLHMDSKP
SIO_010081: YFL023W
subclass of: SO_0000673
so part of: YFL023W
location: 90986..93376
location: region:90986-93376:1
so has part: feature:90986-93376:1:exon

NP_683715.1
type: Protein
SIO_000068: ncbiprotein

S000001871
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:90986-93376:1:exon

YFL022C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FRS2
locus tag: YFL022C
so part of: sequence
location: complement(<93499..>95010)
location: region:93499-95010:-1
so has part: feature:93499-95010:-1:exon
subclass of: SO_0000010

850522
type: Gene
SIO_000068: ncbigene

position:93499:-1
position: 93499
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:95010:-1
position: 95010
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:93499-95010:-1:exon

YFL022C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FRS2
locus tag: YFL022C
product: phenylalanine--tRNA ligase subunit alpha
transcript id: NM_001179944.2
SIO_010081: YFL022C
subclass of: SO_0000673
so part of: YFL022C
location: complement(<93499..>95010)
location: region:93499-95010:-1
so has part: feature:93499-95010:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:93499-95010:-1:exon

YFL022C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FRS2
locus tag: YFL022C
EC number: 6.1.1.20
experiment: EXISTENCE:direct assay:GO:0004826 phenylalanine-tRNA ligase activity [PMID:16162501|PMID:166841]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0006432 phenylalanyl-tRNA aminoacylation [PMID:16162501|PMID:166841]
experiment: EXISTENCE:direct assay:GO:0009328 phenylalanine-tRNA ligase complex [PMID:3049607]
experiment: EXISTENCE:mutant phenotype:GO:0002161 aminoacyl-tRNA editing activity [PMID:27226603]
note: Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase; forms a tetramer with Frs1p to form active enzyme; evolutionarily distant from mitochondrial phenylalanyl-tRNA synthetase based on protein sequence, but substrate binding is similar
codon start: 1
product: phenylalanine--tRNA ligase subunit alpha
translation: MSDFQLEILKKLDELDEIKSTLATFPQHGSQDVLSALNSLKAHNKLEFSKVDTVTYDLTKEGAQILNEGSYEIKLVKLIQELGQLQIKDVMSKLGPQVGKVGQARAFKNGWIAKNASNELELSAKLQNTDLNELTDETQSILAQIKNNSHLDSIDAKILNDLKKRKLIAQGKITDFNVTKGPEFSTDLTKLETDLTSDMVSTNAYKDLKFKPYNFNSQGVQISSGALHPLNKVREEFRQIFFSMGFTEMPSNQYVETGFWNFDALYVPQQHPARDLQDTFYIKDPLTADLPDDKTYMDNIKAVHEQGRFGSIGYRYNWKPEECQKLVLRTHSTAISARMLHDLAKDPKPTRLFSIDRVFRNEAVDATHLAEFHQVEGVLADYNITLGDLIKFMEEFFERMGVTGLRFKPTYNPYTEPSMEIFSWHEGLQKWVEIGNSGMFRPEMLESMGLPKDLRVLGWGLSLERPTMIKYKVQNIRELLGHKVSLDFIETNPAARLDEDLYE
SIO_010081: YFL022C
subclass of: SO_0000673
so part of: YFL022C
location: complement(93499..95010)
location: region:93499-95010:-1
so has part: feature:93499-95010:-1:exon

NP_116631.1
type: Protein
SIO_000068: ncbiprotein

S000001872
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:93499-95010:-1:exon

YFL021W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MEP80
alternative label: NIL1
gene: GAT1
locus tag: YFL021W
gene synonym: MEP80; NIL1
so part of: sequence
location: <95966..>97498
location: region:95966-97498:1
so has part: feature:95966-97498:1:exon
subclass of: SO_0000010

850523
type: Gene
SIO_000068: ncbigene

position:95966:1
position: 95966
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:97498:1
position: 97498
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:95966-97498:1:exon

YFL021W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MEP80
alternative label: NIL1
gene: GAT1
locus tag: YFL021W
gene synonym: MEP80; NIL1
product: Gat1p
transcript id: NM_001179945.1
SIO_010081: YFL021W
subclass of: SO_0000673
so part of: YFL021W
location: <95966..>97498
location: region:95966-97498:1
so has part: feature:95966-97498:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:95966-97498:1:exon

YFL021W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MEP80
alternative label: NIL1
gene: GAT1
locus tag: YFL021W
gene synonym: MEP80; NIL1
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:10799523]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:10799523]
experiment: EXISTENCE:genetic interaction:GO:0001080 nitrogen catabolite activation of transcription from RNA polymerase II promoter [PMID:7568152]
experiment: EXISTENCE:genetic interaction:GO:0043565 sequence-specific DNA binding [PMID:7568152]
experiment: EXISTENCE:genetic interaction:GO:0090294 nitrogen catabolite activation of transcription [PMID:7568152|PMID:8622686]
experiment: EXISTENCE:mutant phenotype:GO:0001080 nitrogen catabolite activation of transcription from RNA polymerase II promoter [PMID:7568152]
experiment: EXISTENCE:mutant phenotype:GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific [PMID:9106207]
experiment: EXISTENCE:mutant phenotype:GO:0010508 positive regulation of autophagy [PMID:26649943]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:26649943]
experiment: EXISTENCE:mutant phenotype:GO:0090294 nitrogen catabolite activation of transcription [PMID:7568152|PMID:8622686]
experiment: EXISTENCE:physical interaction:GO:0005634 nucleus [PMID:19380492]
note: Transcriptional activator of nitrogen catabolite repression genes; contains a GATA-1-type zinc finger DNA-binding motif; activity and localization regulated by nitrogen limitation and Ure2p; different translational starts produce two major and two minor isoforms that are differentially regulated and localized
codon start: 1
product: Gat1p
translation: MHVFFPLLFRPSPVLFIACAYIYIDIYIHCTRCTVVNITMSTNRVPNLDPDLNLNKEIWDLYSSAQKILPDSNRILNLSWRLHNRTSFHRINRIMQHSNSIMDFSASPFASGVNAAGPGNNDLDDTDTDNQQFFLSDMNLNGSSVFENVFDDDDDDDDVETHSIVHSDLLNDMDSASQRASHNASGFPNFLDTSCSSSFDDHFIFTNNLPFLNNNSINNNHSHNSSHNNNSPSIANNTNANTNTNTSASTNTNSPLLRRNPSPSIVKPGSRRNSSVRKKKPALKKIKSSTSVQSSATPPSNTSSNPDIKCSNCTTSTTPLWRKDPKGLPLCNACGLFLKLHGVTRPLSLKTDIIKKRQRSSTKINNNITPPPSSSLNPGAAGKKKNYTASVAASKRKNSLNIVAPLKSQDIPIPKIASPSIPQYLRSNTRHHLSSSVPIEAETFSSFRPDMNMTMNMNLHNASTSSFNNEAFWKPLDSAIDHHSGDTNPNSNMNTTPNGNLSLDWLNLNL
SIO_010081: YFL021W
subclass of: SO_0000673
so part of: YFL021W
location: 95966..97498
location: region:95966-97498:1
so has part: feature:95966-97498:1:exon

NP_116632.1
type: Protein
SIO_000068: ncbiprotein

S000001873
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:95966-97498:1:exon

YFL020C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PAU5
locus tag: YFL020C
so part of: sequence
location: complement(<99231..>99599)
location: region:99231-99599:-1
so has part: feature:99231-99599:-1:exon
subclass of: SO_0000010

850524
type: Gene
SIO_000068: ncbigene

position:99231:-1
position: 99231
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:99599:-1
position: 99599
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:99231-99599:-1:exon

YFL020C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PAU5
locus tag: YFL020C
product: seripauperin PAU5
transcript id: NM_001179946.1
SIO_010081: YFL020C
subclass of: SO_0000673
so part of: YFL020C
location: complement(<99231..>99599)
location: region:99231-99599:-1
so has part: feature:99231-99599:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:99231-99599:-1:exon

YFL020C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PAU5
locus tag: YFL020C
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:18312373]
experiment: EXISTENCE:direct assay:GO:0016020 membrane [PMID:18312373]
note: Member of the seripauperin multigene family; encoded mainly in subtelomeric regions; induced during alcoholic fermentation; induced by low temperature and also by anaerobic conditions; negatively regulated by oxygen and repressed by heme
codon start: 1
product: seripauperin PAU5
translation: MVKLTSIAAGVAAIAAGASAAATTTLSQSDERVNLVELGVYVSDIRAHLAEYYSFQAAHPTETYPVEIAEAVFNYGDFTTMLTGIPADQVTRVITGVPWYSSRLKPAISSALSADGIYTIAN
SIO_010081: YFL020C
subclass of: SO_0000673
so part of: YFL020C
location: complement(99231..99599)
location: region:99231-99599:-1
so has part: feature:99231-99599:-1:exon

NP_116633.1
type: Protein
SIO_000068: ncbiprotein

S000001874
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:99231-99599:-1:exon

YFL019C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YFL019C
so part of: sequence
location: complement(<100252..>100605)
location: region:100252-100605:-1
so has part: feature:100252-100605:-1:exon
subclass of: SO_0000010

850525
type: Gene
SIO_000068: ncbigene

position:100252:-1
position: 100252
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:100605:-1
position: 100605
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:100252-100605:-1:exon

YFL019C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YFL019C
product: uncharacterized protein
transcript id: NM_001348831.1
SIO_010081: YFL019C
subclass of: SO_0000673
so part of: YFL019C
location: complement(<100252..>100605)
location: region:100252-100605:-1
so has part: feature:100252-100605:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:100252-100605:-1:exon

YFL019C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YFL019C
note: hypothetical protein; conserved across S. cerevisiae strains; YFL019C is not an essential gene
codon start: 1
product: uncharacterized protein
translation: MIVELYSNIIEVRRYTTKDSLCSIFESGSTSHFEINQLQVKRLNLLQNQFASVFTSFHPKDNTKGIHINFFSPVTRITDLQYSFFYTNQILFGTRYLIKMIQNFVTGKVFTRTNQSK
SIO_010081: YFL019C
subclass of: SO_0000673
so part of: YFL019C
location: complement(100252..100605)
location: region:100252-100605:-1
so has part: feature:100252-100605:-1:exon

NP_001335772.1
type: Protein
SIO_000068: ncbiprotein

S000001875
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:100252-100605:-1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 100581..100901
location: region:100581-100901:1
so has part: feature:100581-100901:1:region

S000006924
type: SGD
SIO_000068: sgd

position:100581:1
position: 100581
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:100901:1
position: 100901
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:100581-100901:1:region

YNCF0002W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SUF9
locus tag: YNCF0002W
so part of: sequence
location: 101376..101478
location: region:101376-101478:1
so has part: feature:101376-101478:1:exon
subclass of: SO_0000663

850526
type: Gene
SIO_000068: ncbigene

position:101376:1
position: 101376
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:101478:1
position: 101478
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:101376-101478:1:exon

YNCF0002W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
gene: SUF9
locus tag: YNCF0002W
product: tRNA-Pro
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Proline tRNA (tRNA-Pro), predicted by tRNAscan-SE analysis; can mutate to suppress +1 frameshift mutations in proline codons
SIO_010081: YNCF0002W
subclass of: SO_0000673
so part of: YNCF0002W
location: join(101376..101411,101443..101478)
location: region:101376-101478:1
so has part: feature:101376-101411:1:exon
so has part: feature:101443-101478:1:exon

S000006681
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:101376-101411:1:exon

position:101411:1
position: 101411
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:101443-101478:1:exon

position:101443:1
position: 101443
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YFL018C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: HPD1
gene: LPD1
locus tag: YFL018C
gene synonym: HPD1
so part of: sequence
location: complement(<101628..>103127)
location: region:101628-103127:-1
so has part: feature:101628-103127:-1:exon
subclass of: SO_0000010

850527
type: Gene
SIO_000068: ncbigene

position:101628:-1
position: 101628
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:103127:-1
position: 103127
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:101628-103127:-1:exon

YFL018C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: HPD1
gene: LPD1
locus tag: YFL018C
gene synonym: HPD1
product: dihydrolipoyl dehydrogenase
transcript id: NM_001179948.1
SIO_010081: YFL018C
subclass of: SO_0000673
so part of: YFL018C
location: complement(<101628..>103127)
location: region:101628-103127:-1
so has part: feature:101628-103127:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:101628-103127:-1:exon

YFL018C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: HPD1
gene: LPD1
locus tag: YFL018C
gene synonym: HPD1
EC number: 1.8.1.4
experiment: EXISTENCE:direct assay:GO:0004148 dihydrolipoyl dehydrogenase activity [PMID:2821168]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005967 mitochondrial pyruvate dehydrogenase complex [PMID:12756305]
experiment: EXISTENCE:direct assay:GO:0009353 mitochondrial oxoglutarate dehydrogenase complex [PMID:2072900]
experiment: EXISTENCE:direct assay:GO:0042645 mitochondrial nucleoid [PMID:10869431|PMID:11926067]
experiment: EXISTENCE:genetic interaction:GO:0042743 hydrogen peroxide metabolic process [PMID:17110466]
experiment: EXISTENCE:mutant phenotype:GO:0004375 glycine dehydrogenase (decarboxylating) activity [PMID:7498764]
experiment: EXISTENCE:mutant phenotype:GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity [PMID:3528755]
experiment: EXISTENCE:mutant phenotype:GO:0004738 pyruvate dehydrogenase activity [PMID:3528755]
experiment: EXISTENCE:mutant phenotype:GO:0005960 glycine cleavage complex [PMID:7498764]
experiment: EXISTENCE:mutant phenotype:GO:0006090 pyruvate metabolic process [PMID:3528755]
experiment: EXISTENCE:mutant phenotype:GO:0006103 2-oxoglutarate metabolic process [PMID:3528755]
experiment: EXISTENCE:mutant phenotype:GO:0006546 glycine catabolic process [PMID:7498764]
experiment: EXISTENCE:mutant phenotype:GO:0006550 isoleucine catabolic process [PMID:1479341]
experiment: EXISTENCE:mutant phenotype:GO:0006552 leucine catabolic process [PMID:1479341]
experiment: EXISTENCE:mutant phenotype:GO:0006564 L-serine biosynthetic process [PMID:7498764]
experiment: EXISTENCE:mutant phenotype:GO:0006574 valine catabolic process [PMID:1479341]
experiment: EXISTENCE:mutant phenotype:GO:0042743 hydrogen peroxide metabolic process [PMID:17110466]
note: Dihydrolipoamide dehydrogenase; the lipoamide dehydrogenase component (E3) of the pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase multi-enzyme complexes; PDH complex is concentrated in spots within the mitochondrial matrix, often near the ERMES complex and near peroxisomes; LPD1 has a paralog, IRC15, that arose from the whole genome duplication
codon start: 1
product: dihydrolipoyl dehydrogenase
translation: MLRIRSLLNNKRAFSSTVRTLTINKSHDVVIIGGGPAGYVAAIKAAQLGFNTACVEKRGKLGGTCLNVGCIPSKALLNNSHLFHQMHTEAQKRGIDVNGDIKINVANFQKAKDDAVKQLTGGIELLFKKNKVTYYKGNGSFEDETKIRVTPVDGLEGTVKEDHILDVKNIIVATGSEVTPFPGIEIDEEKIVSSTGALSLKEIPKRLTIIGGGIIGLEMGSVYSRLGSKVTVVEFQPQIGASMDGEVAKATQKFLKKQGLDFKLSTKVISAKRNDDKNVVEIVVEDTKTNKQENLEAEVLLVAVGRRPYIAGLGAEKIGLEVDKRGRLVIDDQFNSKFPHIKVVGDVTFGPMLAHKAEEEGIAAVEMLKTGHGHVNYNNIPSVMYSHPEVAWVGKTEEQLKEAGIDYKIGKFPFAANSRAKTNQDTEGFVKILIDSKTERILGAHIIGPNAGEMIAEAGLALEYGASAEDVARVCHAHPTLSEAFKEANMAAYDKAIHC
SIO_010081: YFL018C
subclass of: SO_0000673
so part of: YFL018C
location: complement(101628..103127)
location: region:101628-103127:-1
so has part: feature:101628-103127:-1:exon

NP_116635.1
type: Protein
SIO_000068: ncbiprotein

S000001876
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:101628-103127:-1:exon

YFL017W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SNP2
alternative label: YFL018W-A
gene: SMX2
locus tag: YFL017W-A
gene synonym: SNP2; YFL018W-A
so part of: sequence
location: <103699..>103932
location: region:103699-103932:1
so has part: feature:103699-103932:1:exon
subclass of: SO_0000010

850528
type: Gene
SIO_000068: ncbigene

position:103699:1
position: 103699
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:103932:1
position: 103932
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:103699-103932:1:exon

YFL017W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SNP2
alternative label: YFL018W-A
gene: SMX2
locus tag: YFL017W-A
gene synonym: SNP2; YFL018W-A
product: mRNA splicing protein SMX2
transcript id: NM_001180864.1
SIO_010081: YFL017W-A
subclass of: SO_0000673
so part of: YFL017W-A
location: <103699..>103932
location: region:103699-103932:1
so has part: feature:103699-103932:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:103699-103932:1:exon

YFL017W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SNP2
alternative label: YFL018W-A
gene: SMX2
locus tag: YFL017W-A
gene synonym: SNP2; YFL018W-A
experiment: EXISTENCE:direct assay:GO:0005682 U5 snRNP [PMID:11720284|PMID:11720285]
experiment: EXISTENCE:direct assay:GO:0005685 U1 snRNP [PMID:9012791|PMID:9630245]
experiment: EXISTENCE:direct assay:GO:0046540 U4/U6 x U5 tri-snRNP complex [PMID:10377396|PMID:10449419]
experiment: EXISTENCE:direct assay:GO:0071004 U2-type prespliceosome [PMID:16618970]
note: Core Sm protein Sm G; part of heteroheptameric complex (with Smb1p, Smd1p, Smd2p, Smd3p, Sme1p, and Smx3p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm G
codon start: 1
product: mRNA splicing protein SMX2
translation: MVSTPELKKYMDKKILLNINGSRKVAGILRGYDIFLNVVLDDAMEINGEDPANNHQLGLQTVIRGNSIISLEALDAI
SIO_010081: YFL017W-A
subclass of: SO_0000673
so part of: YFL017W-A
location: 103699..103932
location: region:103699-103932:1
so has part: feature:103699-103932:1:exon

NP_116636.1
type: Protein
SIO_000068: ncbiprotein

S000002965
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:103699-103932:1:exon

YFL017C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PAT1
gene: GNA1
locus tag: YFL017C
gene synonym: PAT1
so part of: sequence
location: complement(<103983..>104462)
location: region:103983-104462:-1
so has part: feature:103983-104462:-1:exon
subclass of: SO_0000010

850529
type: Gene
SIO_000068: ncbigene

position:103983:-1
position: 103983
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:104462:-1
position: 104462
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:103983-104462:-1:exon

YFL017C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PAT1
gene: GNA1
locus tag: YFL017C
gene synonym: PAT1
product: glucosamine 6-phosphate N-acetyltransferase
transcript id: NM_001179949.1
SIO_010081: YFL017C
subclass of: SO_0000673
so part of: YFL017C
location: complement(<103983..>104462)
location: region:103983-104462:-1
so has part: feature:103983-104462:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:103983-104462:-1:exon

YFL017C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PAT1
gene: GNA1
locus tag: YFL017C
gene synonym: PAT1
EC number: 2.3.1.4
experiment: EXISTENCE:direct assay:GO:0004343 glucosamine 6-phosphate N-acetyltransferase activity [PMID:9867860]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0006048 UDP-N-acetylglucosamine biosynthetic process [PMID:9867860]
experiment: EXISTENCE:mutant phenotype:GO:0006048 UDP-N-acetylglucosamine biosynthetic process [PMID:9867860]
note: Glucosamine-6-phosphate acetyltransferase; evolutionarily conserved; required for multiple cell cycle events including passage through START, DNA synthesis, and mitosis; involved in UDP-N-acetylglucosamine synthesis, forms GlcNAc6P from AcCoA
codon start: 1
product: glucosamine 6-phosphate N-acetyltransferase
translation: MSLPDGFYIRRMEEGDLEQVTETLKVLTTVGTITPESFSKLIKYWNEATVWNDNEDKKIMQYNPMVIVDKRTETVAATGNIIIERKIIHELGLCGHIEDIAVNSKYQGQGLGKLLIDQLVTIGFDYGCYKIILDCDEKNVKFYEKCGFSNAGVEMQIRK
SIO_010081: YFL017C
subclass of: SO_0000673
so part of: YFL017C
location: complement(103983..104462)
location: region:103983-104462:-1
so has part: feature:103983-104462:-1:exon

NP_116637.1
type: Protein
SIO_000068: ncbiprotein

S000001877
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:103983-104462:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS603.1; Very weak autonomously replicating sequence
so part of: sequence
location: 104463..104701
location: region:104463-104701:1
so has part: feature:104463-104701:1:region

S000178095
type: SGD
SIO_000068: sgd

position:104463:1
position: 104463
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:104701:1
position: 104701
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:104463-104701:1:region

YFL016C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MDJ1
locus tag: YFL016C
so part of: sequence
location: complement(<104701..>106236)
location: region:104701-106236:-1
so has part: feature:104701-106236:-1:exon
subclass of: SO_0000010

850530
type: Gene
SIO_000068: ncbigene

position:104701:-1
position: 104701
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:106236:-1
position: 106236
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:104701-106236:-1:exon

YFL016C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MDJ1
locus tag: YFL016C
product: Mdj1p
transcript id: NM_001179950.1
SIO_010081: YFL016C
subclass of: SO_0000673
so part of: YFL016C
location: complement(<104701..>106236)
location: region:104701-106236:-1
so has part: feature:104701-106236:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:104701-106236:-1:exon

YFL016C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MDJ1
locus tag: YFL016C
experiment: EXISTENCE:direct assay:GO:0001671 ATPase activator activity [PMID:9973563]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005759 mitochondrial matrix [PMID:15383543]
experiment: EXISTENCE:direct assay:GO:0042026 protein refolding [PMID:9973563]
experiment: EXISTENCE:mutant phenotype:GO:0000002 mitochondrial genome maintenance [PMID:10567545]
experiment: EXISTENCE:mutant phenotype:GO:0006458 'de novo' protein folding [PMID:8168133]
experiment: EXISTENCE:mutant phenotype:GO:0006515 protein quality control for misfolded or incompletely synthesized proteins [PMID:7957078]
experiment: EXISTENCE:mutant phenotype:GO:0009408 response to heat [PMID:8603724]
experiment: EXISTENCE:mutant phenotype:GO:0042026 protein refolding [PMID:8168133]
experiment: EXISTENCE:mutant phenotype:GO:0051082 unfolded protein binding [PMID:8943361]
note: Co-chaperone that stimulates HSP70 protein Ssc1p ATPase activity; involved in protein folding/refolding in the mitochodrial matrix; required for proteolysis of misfolded proteins; member of the HSP40 (DnaJ) family of chaperones
codon start: 1
product: Mdj1p
translation: MAFQQGVLSRCSGVFRHHVGHSRHINNILYRHAIAFASIAPRIPKSSFHTSAIRNNEAFKDPYDTLGLKKSATGAEIKKAYYKLAKKYHPDINKEPDAEKKFHDLQNAYEILSDETKRQQYDQFGPAAFGGGGAAGGAGGGSGSPFGSQFHDFSGFTSAGGSPFGGINFEDLFGAAFGGGGRGSGGASRSSSMFRQYRGDPIEIVHKVSFKDAVFGSKNVQLRFSALDPCSTCSGTGMKPNTHKVSCSTCHGTGTTVHIRGGFQMMSTCPTCNGEGTMKRPQDNCTKCHGEGVQVNRAKTITVDLPHGLQDGDVVRIPGQGSYPDIAVEADLKDSVKLSRGDILVRIRVDKDPNFSIKNKYDIWYDKEIPITTAALGGTVTIPTVEGQKIRIKVAPGTQYNQVISIPNMGVPKTSTIRGDMKVQYKIVVKKPQSLAEKCLWEALADVTNDDMAKKTMQPGTAAGTAINEEILKKQKQEEEKHAKKDDDNTLKRLENFITNTFRKIKGDKKN
SIO_010081: YFL016C
subclass of: SO_0000673
so part of: YFL016C
location: complement(104701..106236)
location: region:104701-106236:-1
so has part: feature:104701-106236:-1:exon

NP_116638.1
type: Protein
SIO_000068: ncbiprotein

S000001878
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:104701-106236:-1:exon

YFL015C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YFL015C
so part of: sequence
location: complement(<106469..>106963)
location: region:106469-106963:-1
so has part: feature:106469-106963:-1:exon
subclass of: SO_0000010

850531
type: Gene
SIO_000068: ncbigene

position:106469:-1
position: 106469
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:106963:-1
position: 106963
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:106469-106963:-1:exon

YFL015C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YFL015C
product: uncharacterized protein
transcript id: NM_001348832.1
SIO_010081: YFL015C
subclass of: SO_0000673
so part of: YFL015C
location: complement(<106469..>106963)
location: region:106469-106963:-1
so has part: feature:106469-106963:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:106469-106963:-1:exon

YFL015C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YFL015C
note: hypothetical protein; conserved across S. cerevisiae strains; partially overlaps dubious ORF YFL015W-A; YFL015C is not an essential gene
codon start: 1
product: uncharacterized protein
translation: MLAYTFPSFNFYVNGFFSFLFLFLFLFPSLLRFYVILCRPLQVATYPLNRCQQYSSLAIFTASGFWLLVLVPRAKGPSTRRHCYRQLAPTHHRPFFSIFGWAVSGIRPLPEIFTWICASPFFLHSLTPPTFSHFSVYQEEKKEKRRTPKNTEQEGNRMCIWMSG
SIO_010081: YFL015C
subclass of: SO_0000673
so part of: YFL015C
location: complement(106469..106963)
location: region:106469-106963:-1
so has part: feature:106469-106963:-1:exon

NP_001335773.1
type: Protein
SIO_000068: ncbiprotein

S000001879
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:106469-106963:-1:exon

YFL014W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: GLP1
alternative label: HOR5
gene: HSP12
locus tag: YFL014W
gene synonym: GLP1; HOR5
so part of: sequence
location: <107256..>107585
location: region:107256-107585:1
so has part: feature:107256-107585:1:exon
subclass of: SO_0000010

850532
type: Gene
SIO_000068: ncbigene

position:107256:1
position: 107256
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:107585:1
position: 107585
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:107256-107585:1:exon

YFL014W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: GLP1
alternative label: HOR5
gene: HSP12
locus tag: YFL014W
gene synonym: GLP1; HOR5
product: lipid-binding protein HSP12
transcript id: NM_001179952.1
SIO_010081: YFL014W
subclass of: SO_0000673
so part of: YFL014W
location: <107256..>107585
location: region:107256-107585:1
so has part: feature:107256-107585:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:107256-107585:1:exon

YFL014W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: GLP1
alternative label: HOR5
gene: HSP12
locus tag: YFL014W
gene synonym: GLP1; HOR5
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005768 endosome [PMID:20797624]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:20797624]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:20797624|PMID:10675505|PMID:16622836]
experiment: EXISTENCE:direct assay:GO:0007155 cell adhesion [PMID:11816034]
experiment: EXISTENCE:direct assay:GO:0008289 lipid binding [PMID:20797624]
experiment: EXISTENCE:mutant phenotype:GO:0007009 plasma membrane organization [PMID:20797624]
experiment: EXISTENCE:mutant phenotype:GO:0034599 cellular response to oxidative stress [PMID:20797624]
experiment: EXISTENCE:mutant phenotype:GO:0034605 cellular response to heat [PMID:20797624]
experiment: EXISTENCE:mutant phenotype:GO:0071470 cellular response to osmotic stress [PMID:20797624]
note: Plasma membrane protein involved in maintaining membrane organization; involved in maintaining organization during stress conditions; induced by heat shock, oxidative stress, osmostress, stationary phase, glucose depletion, oleate and alcohol; protein abundance increased in response to DNA replication stress and dietary restriction; regulated by the HOG and Ras-Pka pathways; required for dietary restriction-induced lifespan extension
codon start: 1
product: lipid-binding protein HSP12
translation: MSDAGRKGFGEKASEALKPDSQKSYAEQGKEYITDKADKVAGKVQPEDNKGVFQGVHDSAEKGKDNAEGQGESLADQARDYMGAAKSKLNDAVEYVSGRVHGEEDPTKK
SIO_010081: YFL014W
subclass of: SO_0000673
so part of: YFL014W
location: 107256..107585
location: region:107256-107585:1
so has part: feature:107256-107585:1:exon

NP_116640.1
type: Protein
SIO_000068: ncbiprotein

S000001880
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:107256-107585:1:exon

YFL013C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: IES1
locus tag: YFL013C
so part of: sequence
location: complement(<107852..>109930)
location: region:107852-109930:-1
so has part: feature:107852-109930:-1:exon
subclass of: SO_0000010

850534
type: Gene
SIO_000068: ncbigene

position:107852:-1
position: 107852
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:109930:-1
position: 109930
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:107852-109930:-1:exon

YFL013C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: IES1
locus tag: YFL013C
product: Ies1p
transcript id: NM_001179953.1
SIO_010081: YFL013C
subclass of: SO_0000673
so part of: YFL013C
location: complement(<107852..>109930)
location: region:107852-109930:-1
so has part: feature:107852-109930:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:107852-109930:-1:exon

YFL013C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: IES1
locus tag: YFL013C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22932476|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0006338 chromatin remodeling [PMID:12887900]
experiment: EXISTENCE:direct assay:GO:0031011 Ino80 complex [PMID:12887900]
experiment: EXISTENCE:physical interaction:GO:0031011 Ino80 complex [PMID:24034245]
note: Subunit of the INO80 chromatin remodeling complex; relocalizes to the cytosol in response to hypoxia
codon start: 1
product: Ies1p
translation: MGKRVYDPIHDTFQLREDNSDETKADSPMQSVKSGSQEEASPSSIQSETETVTTKSIPVIHEIEIDDKNDDDSTQSEEENTNILLNFEPSTVPEATGASTATGPVTTNTVRRKPKESNASKYNRHLKKPDGEPFNRKDIQFSFMQELLMDKRQIFTNVLKPLYKNSIVPINIDGDKLSINVTDKEYDARTFVFNDKLTFAQLYVLTIATSIKCSKILRDKLLLDQQVAFSTCVLALLVNIGRLNTTINFYLEMTSQLRTFHSVPVLQLHANDPKLLQDTPRLKSILKNLPWGNEQLSLMETYKKVDQNDGEVDTVNKFNIINMLFSICDNSGLIDKRFLSKYVEVESKAQEQDMVDEQNEVKETEAENEKQESKAAYATTLFDILDYSKYEPKDRSNILIWLLYIHLETNLSQEEVEESVRFFNGLEDGAPAGKFILRCTERSYDTDPEDELEFGANQRIKRREFMSKMEEGRKRERTNVTEVKKPSIGGDKSEEDGEGEDDKSEETVEETRSLLTPTPILESSSPMTLNRKKVTPQLPKVTPAAPTETEEEITSAAIIDKNDLNLTPLKKYNSSATVNKVDKLISLDLNKHVSENGKTQEEFLADLKKSQVPNRLKRRDIGLIKIFNEFEDIPVASVLGIRGKKRKKFKDNLLGFETDFMKNLGASKKVLLNKIERAEIDDEEATAMFKLE
SIO_010081: YFL013C
subclass of: SO_0000673
so part of: YFL013C
location: complement(107852..109930)
location: region:107852-109930:-1
so has part: feature:107852-109930:-1:exon

NP_116641.1
type: Protein
SIO_000068: ncbiprotein

S000001881
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:107852-109930:-1:exon

YFL012W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YFL012W
so part of: sequence
location: <110647..>111093
location: region:110647-111093:1
so has part: feature:110647-111093:1:exon
subclass of: SO_0000010

850535
type: Gene
SIO_000068: ncbigene

position:110647:1
position: 110647
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:111093:1
position: 111093
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:110647-111093:1:exon

YFL012W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YFL012W
product: uncharacterized protein
transcript id: NM_001179954.1
SIO_010081: YFL012W
subclass of: SO_0000673
so part of: YFL012W
location: <110647..>111093
location: region:110647-111093:1
so has part: feature:110647-111093:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:110647-111093:1:exon

YFL012W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YFL012W
note: hypothetical protein; transcribed during sporulation; null mutant exhibits increased resistance to rapamycin
codon start: 1
product: uncharacterized protein
translation: MPKSRPKRTIASSSSVFYGSSPFQNDGYIKVMELVSHIVIEINHSPTATTDETRKQNNPELKVKEPVCNLKKWENNTNFILEDHTKNKTKLSSTDRIRKWFRRHILKEEIEILSHGKQLSSIDEDYCPSNVLVGCSRDLNKLRSFQNF
SIO_010081: YFL012W
subclass of: SO_0000673
so part of: YFL012W
location: 110647..111093
location: region:110647-111093:1
so has part: feature:110647-111093:1:exon

NP_116643.1
type: Protein
SIO_000068: ncbiprotein

S000001882
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:110647-111093:1:exon

YFL011W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HXT10
locus tag: YFL011W
so part of: sequence
location: <112345..>113985
location: region:112345-113985:1
so has part: feature:112345-113985:1:exon
subclass of: SO_0000010

850536
type: Gene
SIO_000068: ncbigene

position:112345:1
position: 112345
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:113985:1
position: 113985
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:112345-113985:1:exon

YFL011W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HXT10
locus tag: YFL011W
product: hexose transporter HXT10
transcript id: NM_001179955.1
SIO_010081: YFL011W
subclass of: SO_0000673
so part of: YFL011W
location: <112345..>113985
location: region:112345-113985:1
so has part: feature:112345-113985:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:112345-113985:1:exon

YFL011W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: HXT10
locus tag: YFL011W
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0005353 fructose transmembrane transporter activity [PMID:10618490]
experiment: EXISTENCE:mutant phenotype:GO:0005354 galactose transmembrane transporter activity [PMID:10618490]
experiment: EXISTENCE:mutant phenotype:GO:0005355 glucose transmembrane transporter activity [PMID:10618490]
experiment: EXISTENCE:mutant phenotype:GO:0008645 hexose transmembrane transport [PMID:10618490]
experiment: EXISTENCE:mutant phenotype:GO:0015578 mannose transmembrane transporter activity [PMID:10618490]
note: Hexose transporter; expressed at low levels and expression is repressed by glucose
codon start: 1
product: hexose transporter HXT10
translation: MVSSSVSILGTSAKASTSLSRKDEIKLTPETREASLDIPYKPIIAYWTVMGLCLMIAFGGFIFGWDTGTISGFINQTDFKRRFGELQRDGSFQLSDVRTGLIVGIFNIGCALGGLTLGRLGDIYGRKIGLMCVILVYVVGIVIQIASSDKWYQYFIGRIVSGMGVGGVAVLSPTLISEISPKHLRGTCVSFYQLMITLGIFLGYCTNYGTKKYSNSIQWRVPLGLCFAWAIFMVIGMVMVPESPRYLVEKGKYEEARRSLAKSNKVTVTDPGVVFEFDTIVANMELERAVGNASWHELFSNKGAILPRVIMGIVIQSLQQLTGCNYFFYYGTTIFNAVGMQDSFETSIVLGAVNFASTFVALYIVDKFGRRKCLLWGSASMAICFVIFATVGVTRLWPQGKDQPSSQSAGNVMIVFTCFFIFSFAITWAPIAYVIVAETYPLRVKNRAMAIAVGANWMWGFLIGFFTPFITRSIGFSYGYVFMGCLIFSYFYVFFFVCETKGLTLEEVNEMYEERIKPWKSGGWIPSSRRTPQPTSSTPLVIVDSK
SIO_010081: YFL011W
subclass of: SO_0000673
so part of: YFL011W
location: 112345..113985
location: region:112345-113985:1
so has part: feature:112345-113985:1:exon

NP_116644.1
type: Protein
SIO_000068: ncbiprotein

S000001883
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:112345-113985:1:exon

YFL010W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YFL011W-A
gene: AUA1
locus tag: YFL010W-A
gene synonym: YFL011W-A
so part of: sequence
location: <114990..>115274
location: region:114990-115274:1
so has part: feature:114990-115274:1:exon
subclass of: SO_0000010

850537
type: Gene
SIO_000068: ncbigene

position:114990:1
position: 114990
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:115274:1
position: 115274
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:114990-115274:1:exon

YFL010W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YFL011W-A
gene: AUA1
locus tag: YFL010W-A
gene synonym: YFL011W-A
product: Aua1p
transcript id: NM_001180024.1
SIO_010081: YFL010W-A
subclass of: SO_0000673
so part of: YFL010W-A
location: <114990..>115274
location: region:114990-115274:1
so has part: feature:114990-115274:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:114990-115274:1:exon

YFL010W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YFL011W-A
gene: AUA1
locus tag: YFL010W-A
gene synonym: YFL011W-A
experiment: EXISTENCE:mutant phenotype:GO:0006865 amino acid transport [PMID:8497191]
note: Protein required for the negative regulation by ammonia of Gap1p; Gap1p is a general amino acid permease
codon start: 1
product: Aua1p
translation: MDRSLQVYICMYPYLDGSKQYRFDELISFYRPCPKSLDNIKSHYRQIHHQIRRRTHQHHQIRRRTHQHHHRSNCSRQRQCLVRHSCGRQMRVLA
SIO_010081: YFL010W-A
subclass of: SO_0000673
so part of: YFL010W-A
location: 114990..115274
location: region:114990-115274:1
so has part: feature:114990-115274:1:exon

NP_116645.1
type: Protein
SIO_000068: ncbiprotein

S000001955
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:114990-115274:1:exon

YFL010C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: WWM1
locus tag: YFL010C
so part of: sequence
location: complement(<115108..>115743)
location: region:115108-115743:-1
so has part: feature:115108-115743:-1:exon
subclass of: SO_0000010

850538
type: Gene
SIO_000068: ncbigene

position:115108:-1
position: 115108
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:115743:-1
position: 115743
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:115108-115743:-1:exon

YFL010C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: WWM1
locus tag: YFL010C
product: Wwm1p
transcript id: NM_001179956.1
SIO_010081: YFL010C
subclass of: SO_0000673
so part of: YFL010C
location: complement(<115108..>115743)
location: region:115108-115743:-1
so has part: feature:115108-115743:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:115108-115743:-1:exon

YFL010C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: WWM1
locus tag: YFL010C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:12062425|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095|PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
note: WW domain containing hypothetical protein; binds to Mca1p, a caspase-related protease that regulates H2O2-induced apoptosis; overexpression causes G1 phase growth arrest and clonal death that is suppressed by overexpression of MCA1
codon start: 1
product: Wwm1p
translation: MAQSKSNPPQVPSGWKAVFDDEYQTWYYVDLSTNSSQWEPPRGTTWPRPKGPPPGVNNEKSSRQQADQAPPPYSSQSTPQVQAGAQAQQPRYYQPQQPQYPQYPQQQRYYPQQAPMPAAAPQQAYYGTAPSTSKGSGHGGAMMGGLLGVGAGLLGGAMLEHAFDDHNYDGPDTVVVENNYYGDDAGGSDGGFDDAGGFDGGFDDGFDGSDF
SIO_010081: YFL010C
subclass of: SO_0000673
so part of: YFL010C
location: complement(115108..115743)
location: region:115108-115743:-1
so has part: feature:115108-115743:-1:exon

NP_570898.1
type: Protein
SIO_000068: ncbiprotein

S000001884
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:115108-115743:-1:exon

YFL009W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CDC4
locus tag: YFL009W
so part of: sequence
location: <116145..>118484
location: region:116145-118484:1
so has part: feature:116145-118484:1:exon
subclass of: SO_0000010

850539
type: Gene
SIO_000068: ncbigene

position:116145:1
position: 116145
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:118484:1
position: 118484
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:116145-118484:1:exon

YFL009W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CDC4
locus tag: YFL009W
product: SCF ubiquitin ligase complex subunit CDC4
transcript id: NM_001179957.1
SIO_010081: YFL009W
subclass of: SO_0000673
so part of: YFL009W
location: <116145..>118484
location: region:116145-118484:1
so has part: feature:116145-118484:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:116145-118484:1:exon

YFL009W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CDC4
locus tag: YFL009W
experiment: EXISTENCE:direct assay:GO:0004842 ubiquitin-protein transferase activity [PMID:9346239]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:11080155]
experiment: EXISTENCE:direct assay:GO:0006511 ubiquitin-dependent protein catabolic process [PMID:9346238|PMID:9346239]
experiment: EXISTENCE:direct assay:GO:0016363 nuclear matrix [PMID:2244914]
experiment: EXISTENCE:direct assay:GO:0016567 protein ubiquitination [PMID:23645675]
experiment: EXISTENCE:direct assay:GO:0019005 SCF ubiquitin ligase complex [PMID:9346238|PMID:9346239]
experiment: EXISTENCE:direct assay:GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [PMID:9346238|PMID:9346239]
experiment: EXISTENCE:direct assay:GO:0043130 ubiquitin binding [PMID:21070969]
experiment: EXISTENCE:direct assay:GO:0043224 nuclear SCF ubiquitin ligase complex [PMID:11080155]
experiment: EXISTENCE:direct assay:GO:0050815 phosphoserine residue binding [PMID:23314252]
experiment: EXISTENCE:direct assay:GO:0061630 ubiquitin protein ligase activity [PMID:9346238]
experiment: EXISTENCE:genetic interaction:GO:0000086 G2/M transition of mitotic cell cycle [PMID:7954792]
experiment: EXISTENCE:mutant phenotype:GO:0000082 G1/S transition of mitotic cell cycle [PMID:10409741]
experiment: EXISTENCE:mutant phenotype:GO:0000086 G2/M transition of mitotic cell cycle [PMID:10409741]
experiment: EXISTENCE:mutant phenotype:GO:0051321 meiotic cell cycle [PMID:328339]
experiment: EXISTENCE:mutant phenotype:GO:0061630 ubiquitin protein ligase activity [PMID:21098119]
experiment: EXISTENCE:physical interaction:GO:0019005 SCF ubiquitin ligase complex [PMID:9346238|PMID:9346239]
note: F-box protein required for both the G1/S and G2/M phase transitions; modular substrate specificity factor which associates with core SCF (Cdc53p, Skp1p and Hrt1p/Rbx1p) to form the SCFCdc4 complex; SCFCdc4 acts as a ubiquitin-protein ligase directing ubiquitination of cyclin-dependent kinase (CDK) phosphorylated substrates, such as: Sic1p, Far1p, Cdc6p, Clb6p, and Cln3p
codon start: 1
product: SCF ubiquitin ligase complex subunit CDC4
translation: MGSFPLAEFPLRDIPVPYSYRVSGGIASSGSVTALVTAAGTHRNSSTAKTVETEDGEEDIDEYQRKRAAGSGESTPERSDFKRVKHDNHKTLHPVNLQNTGAASVDNDGLHNLTDISNDAEKLLMSVDDGSAAPSTLSVNMGVASHNVAAPTTVNAATITGSDVSNNVNSATINNPMEEGALPLSPTASSPGTTTPLAKTTKTINNNNNIADLIESKDSIISPEYLSDEIFSAINNNLPHAYFKNLLFRLVANMDRSELSDLGTLIKDNLKRDLITSLPFEISLKIFNYLQFEDIINSLGVSQNWNKIIRKSTSLWKKLLISENFVSPKGFNSLNLKLSQKYPKLSQQDRLRLSFLENIFILKNWYNPKFVPQRTTLRGHMTSVITCLQFEDNYVITGADDKMIRVYDSINKKFLLQLSGHDGGVWALKYAHGGILVSGSTDRTVRVWDIKKGCCTHVFKGHNSTVRCLDIVEYKNIKYIVTGSRDNTLHVWKLPKESSVPDHGEEHDYPLVFHTPEENPYFVGVLRGHMASVRTVSGHGNIVVSGSYDNTLIVWDVAQMKCLYILSGHTDRIYSTIYDHERKRCISASMDTTIRIWDLENIWNNGECSYATNSASPCAKILGAMYTLQGHTALVGLLRLSDKFLVSAAADGSIRGWDANDYSRKFSYHHTNLSAITTFYVSDNILVSGSENQFNIYNLRSGKLVHANILKDADQIWSVNFKGKTLVAAVEKDGQSFLEILDFSKASKINYVSNPVNSSSSSLESISTSLGLTRTTIIP
SIO_010081: YFL009W
subclass of: SO_0000673
so part of: YFL009W
location: 116145..118484
location: region:116145-118484:1
so has part: feature:116145-118484:1:exon

NP_116585.1
type: Protein
SIO_000068: ncbiprotein

S000001885
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:116145-118484:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS603.5; Autonomously replicating sequence on Chromosome VI; activated early in S phase in 50% of cell cycles
so part of: sequence
location: 118637..118957
location: region:118637-118957:1
so has part: feature:118637-118957:1:region

S000007645
type: SGD
SIO_000068: sgd

position:118637:1
position: 118637
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:118957:1
position: 118957
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:118637-118957:1:region

YFL008W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CHL10
gene: SMC1
locus tag: YFL008W
gene synonym: CHL10
so part of: sequence
location: <119429..>123106
location: region:119429-123106:1
so has part: feature:119429-123106:1:exon
subclass of: SO_0000010

850540
type: Gene
SIO_000068: ncbigene

position:119429:1
position: 119429
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:123106:1
position: 123106
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:119429-123106:1:exon

YFL008W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CHL10
gene: SMC1
locus tag: YFL008W
gene synonym: CHL10
product: cohesin subunit SMC1
transcript id: NM_001179958.1
SIO_010081: YFL008W
subclass of: SO_0000673
so part of: YFL008W
location: <119429..>123106
location: region:119429-123106:1
so has part: feature:119429-123106:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:119429-123106:1:exon

YFL008W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CHL10
gene: SMC1
locus tag: YFL008W
gene synonym: CHL10
experiment: EXISTENCE:direct assay:GO:0000217 DNA secondary structure binding [PMID:9727028]
experiment: EXISTENCE:direct assay:GO:0003680 minor groove of adenine-thymine-rich DNA binding [PMID:9727028]
experiment: EXISTENCE:direct assay:GO:0003690 double-stranded DNA binding [PMID:9727028]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0030892 mitotic cohesin complex [PMID:9990856]
experiment: EXISTENCE:genetic interaction:GO:0007064 mitotic sister chromatid cohesion [PMID:9335333]
experiment: EXISTENCE:mutant phenotype:GO:0000070 mitotic sister chromatid segregation [PMID:8276886]
experiment: EXISTENCE:mutant phenotype:GO:0006302 double-strand break repair [PMID:11448778|PMID:15280507]
note: Subunit of the multiprotein cohesin complex; essential protein involved in chromosome segregation and in double-strand DNA break repair; SMC chromosomal ATPase family member, binds DNA with a preference for DNA with secondary structure
codon start: 1
product: cohesin subunit SMC1
translation: MGRLVGLELSNFKSYRGVTKVGFGESNFTSIIGPNGSGKSNMMDAISFVLGVRSNHLRSNILKDLIYRGVLNDENSDDYDNEGAASSNPQSAYVKAFYQKGNKLVELMRIISRNGDTSYKIDGKTVSYKDYSIFLENENILIKAKNFLVFQGDVEQIAAQSPVELSRMFEEVSGSIQYKKEYEELKEKIEKLSKSATESIKNRRRIHGELKTYKEGINKNEEYRKQLDKKNELQKFQALWQLYHLEQQKEELTDKLSALNSEISSLKGKINNEMKSLQRSKSSFVKESAVISKQKSKLDYIFKDKEKLVSDLRLIKVPQQAAGKRISHIEKRIESLQKDLQRQKTYVERFETQLKVVTRSKEAFEEEIKQSARNYDKFKLNENDLKTYNCLHEKYLTEGGSILEEKIAVLNNDKREIQEELERFNKRADISKRRITEELSITGEKLDTQLNDLRVSLNEKNALHTERLHELKKLQSDIESANNQEYDLNFKLRETLVKIDDLSANQRETMKERKLRENIAMLKRFFPGVKGLVHDLCHPKKEKYGLAVSTILGKNFDSVIVENLTVAQECIAFLKKQRAGTASFIPLDTIETELPTLSLPDSQDYILSINAIDYEPEYEKAMQYVCGDSIICNTLNIAKDLKWKKGIRGKLVTIEGALIHKAGLMTGGISGDANNRWDKEEYQSLMSLKDKLLIQIDELSNGQRSNSIRAREVENSVSLLNSDIANLRTQVTQQKRSLDENRLEIKYHNDLIEKEIQPKITELKKKLDDLENTKDNLVKEKEALQNNIFKEFTSKIGFTIKEYENHSGELMRQQSKELQQLQKQILTVENKLQFETDRLSTTQRRYEKAQKDLENAQVEMKSLEEQEYAIEMKIGSIESKLEEHKNHLDELQKKFVTKQSELNSSEDILEDMNSNLQVLKRERDGIKEDIEKFDLERVTALKNCKISNINIPISSETTIDDLPISSTDNEAITISNSIDINYKGLPKKYKENNTDSARKELEQKIHEVEEILNELQPNARALERYDEAEGRFEVINNETEQLKAEEKKILNQFLKIKKKRKELFEKTFDYVSDHLDAIYRELTKNPNSNVELAGGNASLTIEDEDEPFNAGIKYHATPPLKRFKDMEYLSGGEKTVAALALLFAINSYQPSPFFVLDEVDAALDITNVQRIAAYIRRHRNPDLQFIVISLKNTMFEKSDALVGVYRQQQENSSKIITLDLSNYAE
SIO_010081: YFL008W
subclass of: SO_0000673
so part of: YFL008W
location: 119429..123106
location: region:119429-123106:1
so has part: feature:119429-123106:1:exon

NP_116647.1
type: Protein
SIO_000068: ncbiprotein

S000001886
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:119429-123106:1:exon

YFL007W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YFL006W
gene: BLM10
locus tag: YFL007W
gene synonym: YFL006W
so part of: sequence
location: <123479..>129910
location: region:123479-129910:1
so has part: feature:123479-129910:1:exon
subclass of: SO_0000010

850541
type: Gene
SIO_000068: ncbigene

position:123479:1
position: 123479
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:129910:1
position: 129910
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:123479-129910:1:exon

YFL007W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YFL006W
gene: BLM10
locus tag: YFL007W
gene synonym: YFL006W
product: Blm10p
transcript id: NM_001179959.1
SIO_010081: YFL007W
subclass of: SO_0000673
so part of: YFL007W
location: <123479..>129910
location: region:123479-129910:1
so has part: feature:123479-129910:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:123479-129910:1:exon

YFL007W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YFL006W
gene: BLM10
locus tag: YFL007W
gene synonym: YFL006W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:12973301|PMID:15778719|PMID:22908043]
experiment: EXISTENCE:direct assay:GO:0016504 peptidase activator activity [PMID:22025621]
experiment: EXISTENCE:direct assay:GO:0034515 proteasome storage granule [PMID:23982732]
experiment: EXISTENCE:direct assay:GO:0061136 regulation of proteasomal protein catabolic process [PMID:22025621]
experiment: EXISTENCE:direct assay:GO:0070628 proteasome binding [PMID:22025621]
experiment: EXISTENCE:genetic interaction:GO:0043248 proteasome assembly [PMID:17911101]
experiment: EXISTENCE:mutant phenotype:GO:0043248 proteasome assembly [PMID:12973301]
experiment: EXISTENCE:mutant phenotype:GO:0070628 proteasome binding [PMID:22025621]
experiment: EXISTENCE:mutant phenotype:GO:1902906 proteasome storage granule assembly [PMID:23982732]
experiment: EXISTENCE:mutant phenotype:GO:1990236 proteasome core complex import into nucleus [PMID:23982732]
note: Proteasome activator; binds the core proteasome (CP) and stimulates proteasome-mediated protein degradation by inducing gate opening; required for sequestering CP into proteasome storage granule (PSG) during quiescent phase and for nuclear import of CP in proliferating cells; required for resistance to bleomycin, may be involved in protecting against oxidative damage; similar to mammalian PA200
codon start: 1
product: Blm10p
translation: MTANNDDDIKSPIPITNKTLSQLKRFERSPGRPSSSQGEIKRKKSRLYAADGRPHSPLRARSATPTLQDQKLFNGMDSTSLLNERLQHYTLDYVSDRAQHMKNIYDPSSRWFSRSVRPEFPIEEFLPYKTESHEDQAKYLCHVLVNLYIAISSLDIQGLISISSKDLADLKKEVDDLALKTDLFRLSNNTAENDLLGNDIADYDDAEGLEDELDEYFDLAGPDFNATGKITAKSATIVNVNHWTNELKNCLHFDFPVALRKSLATVYYYLSLVQGQKVYRQMHVDMFERLVSLDDDRTNFTELLQKQGLLLDHQIMLNFLCEFLPYPDPDYARYELSSKEDLQLFRLLLKHAHNAKPFFDKSKESLLVDTMNFLLSSLAPSTMMAVMPIVTSVVPYHYHIHSKIIDYFPFCYSIWSSVSANVAIDTHMYDFVGSISKDVHNKILSSEHEKDVVGVEFGEFGIFTDDQMTFMFNRLQGHLRTDGQIHSYSRTVKPFVYAINGSKKDRFFEKLVSLAKAIETFIHPSNNGFWTKPNAKFVHAFIKSYHGRVKYEEDICARGVTNGICLTSFCHEEIVEIFLNIISLGSQNKNPDIANYYISCFAYLLELDPSNAYLIYDKILIDLYDTLADQFINSRHRIISSLKQFTRVIRFIVMDKLYRVHITNVLSMLVSKLDMNDTNLTSNLINGIVSIAAFIPIQDLTGEDDYISFESDTLPLVQQHFYHIKCGESSKTFRVDDELLNNAFKASTTVFQSMLKVYVEKIFQLVDVDLEDSLVTKINQTTMILQESMDDKIFNYFASLLQRNFWSNDSFKEKDPNYELVTIPLAALVRRNNGLSKELVRTLLFHIKEQIKRGAGSVRSTSEIQQRDVKLVLYLTALNDVLRQCHESLLEYSDELITFMKYLYDNVTNPPLDVITSIVIHSALATLCTTEITDCRLFPEDSKIPEKDRWGGLQFDPRRFDKQHLSFQWHVPSSDEITLSISILESLSEYCINNVEELMKAPRHDSEYGDMIQKYVLVMTHTLSGSSLLFDPDFNKYRTQSNLSYREKLILLKNIRENNCDPQELDIDIEQIRSGKDDEDYIESKDIEAGLNAGVSDVVQLRDEFPDELIVDEEVVSEMPSGVNTPIAGTHGTDNSAMSSDLAFRDLDIYTCNYYFGNTTEEKLQNPQYLQVHRVRARIGHFFHKLYVFLSTNFENNTNMFQILLHGLKVWFTDLGQETVFNEDPNAFIDVDFLENVQSLSHVNEPFTRTNFAIRANSLHQSRVLLHSTNRKASKLENLLLVDIIQLATSLYPDIYKPAQGTLVHCMKQLVGSYGVVINKIIPSLEKAIKDHDYMKIQVILNVLLIKKIHRKLMTDYKDIGRLIFLLIECCRVNELEIGMYADKILTDIVIGIKIPSSVCVISDQAFLPLAPPDGTINLQVEAVKLAKKKKREYYLSLLVDLQDKLLDKLDNEKDMGWKIRMFILRFVTQIQSNLESKPDKRAVFSIISQISTKHPEIIHLVVKSLLSTCNKIISLSDYEYDITRAYKNEFNPSFVEILDTSTTSFPKTFTEEMNNFDNPKYFIDLRAYVGWLCWGRLMYVMSPKALKLNLRENELEVLKTAGHLLTREFLRDVTMNLVQDNETRGVFSSGNVSFFSLVILLISSGFCELNMSDLFELCESYYNKDDKASMIMSVEIVAGLVCGSKFMSVSDLDKRDTFIENFLAKCLDYELNHDAFEIWSTLAWWLPAVVDLRRSKTFFCHFINADGMFDRESDAATHQTSKIYMLRSILMSMEFRAPDVGKLFDELVFDHPYDQVRQAVAKLLTTLVQNQSNPSISDPTTLLEAERNDPDGLGLPLKSVPEKVDAYIKKQFEIIKNLEDSVVGLNPQQFIKTDYFYRTSTIFYWIKEMARGPNKVLLVPYLVDYVLPFLIGLVKHKDVCALASLDPVRLYAGLGYMPIRKNHVAAIVDYVCSSNVALSSNQTKLQLAFIQHFLSAELLQLTEEEKNKILEFVVSNLYN…
SIO_010081: YFL007W
subclass of: SO_0000673
so part of: YFL007W
location: 123479..129910
location: region:123479-129910:1
so has part: feature:123479-129910:1:exon

NP_116648.2
type: Protein
SIO_000068: ncbiprotein

S000001887
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:123479-129910:1:exon

YFL007W
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
alternative label: YFL006W
gene: BLM10
locus tag: YFL007W
gene synonym: YFL006W
note: ARS604; Extremely inefficient ARS on Chromosome VI
SIO_010081: YFL007W
subclass of: SO_0000673
so part of: YFL007W
location: 127751..128071
location: region:127751-128071:1
so has part: feature:127751-128071:1:exon

S000007636
type: SGD
SIO_000068: sgd

position:127751:1
position: 127751
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:128071:1
position: 128071
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:127751-128071:1:exon

YFL005W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SRO6
gene: SEC4
locus tag: YFL005W
gene synonym: SRO6
so part of: sequence
location: <130334..>130981
location: region:130334-130981:1
so has part: feature:130334-130981:1:exon
subclass of: SO_0000010

850543
type: Gene
SIO_000068: ncbigene

position:130334:1
position: 130334
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:130981:1
position: 130981
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:130334-130981:1:exon

YFL005W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SRO6
gene: SEC4
locus tag: YFL005W
gene synonym: SRO6
product: Rab family GTPase SEC4
transcript id: NM_001179961.1
SIO_010081: YFL005W
subclass of: SO_0000673
so part of: YFL005W
location: <130334..>130981
location: region:130334-130981:1
so has part: feature:130334-130981:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:130334-130981:1:exon

YFL005W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SRO6
gene: SEC4
locus tag: YFL005W
gene synonym: SRO6
experiment: EXISTENCE:direct assay:GO:0000131 incipient cellular bud site [PMID:9128251]
experiment: EXISTENCE:direct assay:GO:0003924 GTPase activity [PMID:2111819]
experiment: EXISTENCE:direct assay:GO:0005525 GTP binding [PMID:2111819]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005741 mitochondrial outer membrane [PMID:16407407]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:16622836]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0006887 exocytosis [PMID:15772160]
experiment: EXISTENCE:direct assay:GO:0030133 transport vesicle [PMID:23079598]
experiment: EXISTENCE:direct assay:GO:0031982 vesicle [PMID:12456647]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:22832273]
experiment: EXISTENCE:genetic interaction:GO:0006914 autophagy [PMID:20444978]
experiment: EXISTENCE:genetic interaction:GO:0007107 membrane addition at site of cytokinesis [PMID:12456647]
experiment: EXISTENCE:mutant phenotype:GO:0006893 Golgi to plasma membrane transport [PMID:9017592]
experiment: EXISTENCE:mutant phenotype:GO:0006906 vesicle fusion [PMID:9017592]
experiment: EXISTENCE:mutant phenotype:GO:0006914 autophagy [PMID:20444978]
experiment: EXISTENCE:mutant phenotype:GO:0007107 membrane addition at site of cytokinesis [PMID:12456647]
experiment: EXISTENCE:mutant phenotype:GO:0031321 ascospore-type prospore assembly [PMID:9425151]
note: Rab family GTPase; essential for vesicle-mediated exocytic secretion and autophagy; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane; exocyst association is negatively regulated via phosphorylation by Cdc5p during cytokinesis
codon start: 1
product: Rab family GTPase SEC4
translation: MSGLRTVSASSGNGKSYDSIMKILLIGDSGVGKSCLLVRFVEDKFNPSFITTIGIDFKIKTVDINGKKVKLQLWDTAGQERFRTITTAYYRGAMGIILVYDVTDERTFTNIKQWFKTVNEHANDEAQLLLVGNKSDMETRVVTADQGEALAKELGIPFIESSAKNDDNVNEIFFTLAKLIQEKIDSNKLVGVGNGKEGNISINSGSGNSSKSNCC
SIO_010081: YFL005W
subclass of: SO_0000673
so part of: YFL005W
location: 130334..130981
location: region:130334-130981:1
so has part: feature:130334-130981:1:exon

NP_116650.1
type: Protein
SIO_000068: ncbiprotein

S000001889
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:130334-130981:1:exon

YNCF0003C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RUF20
locus tag: YNCF0003C
so part of: sequence
location: complement(131061..131503)
location: region:131061-131503:-1
so has part: feature:131061-131503:-1:exon
subclass of: SO_0000011

9164889
type: Gene
SIO_000068: ncbigene

position:131061:-1
position: 131061
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:131503:-1
position: 131503
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:131061-131503:-1:exon

YNCF0003C
type: Non Coding RNA
subclass of: SO_0000655
RO_0002162: 559292
nc RNA class: other
gene: RUF20
locus tag: YNCF0003C
product: RUF20
note: RNA of Unknown Function
transcript id: NR_132173.1
SIO_010081: YNCF0003C
subclass of: SO_0000673
so part of: YNCF0003C
location: complement(131061..131503)
location: region:131061-131503:-1
so has part: feature:131061-131503:-1:exon

S000130127
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:131061-131503:-1:exon

YFL004W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PHM1
gene: VTC2
locus tag: YFL004W
gene synonym: PHM1
so part of: sequence
location: <131810..>134296
location: region:131810-134296:1
so has part: feature:131810-134296:1:exon
subclass of: SO_0000010

850544
type: Gene
SIO_000068: ncbigene

position:131810:1
position: 131810
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:134296:1
position: 134296
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:131810-134296:1:exon

YFL004W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PHM1
gene: VTC2
locus tag: YFL004W
gene synonym: PHM1
product: vacuolar transporter chaperone
transcript id: NM_001179962.1
SIO_010081: YFL004W
subclass of: SO_0000673
so part of: YFL004W
location: <131810..>134296
location: region:131810-134296:1
so has part: feature:131810-134296:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:131810-134296:1:exon

YFL004W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PHM1
gene: VTC2
locus tag: YFL004W
gene synonym: PHM1
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:11823419|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005516 calmodulin binding [PMID:17079729]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:17079729]
experiment: EXISTENCE:direct assay:GO:0007034 vacuolar transport [PMID:17079729]
experiment: EXISTENCE:direct assay:GO:0016237 lysosomal microautophagy [PMID:17079729]
experiment: EXISTENCE:genetic interaction:GO:0006797 polyphosphate metabolic process [PMID:11102525]
experiment: EXISTENCE:mutant phenotype:GO:0006797 polyphosphate metabolic process [PMID:11102525]
experiment: EXISTENCE:mutant phenotype:GO:0007034 vacuolar transport [PMID:17079729]
experiment: EXISTENCE:mutant phenotype:GO:0008104 protein localization [PMID:10480897]
experiment: EXISTENCE:mutant phenotype:GO:0016237 lysosomal microautophagy [PMID:17079729]
experiment: EXISTENCE:mutant phenotype:GO:0042144 vacuole fusion, non-autophagic [PMID:11823419]
experiment: EXISTENCE:physical interaction:GO:0033254 vacuolar transporter chaperone complex [PMID:11823419]
note: Regulatory subunit of vacuolar transporter chaperone (VTC) complex; involved in membrane trafficking, vacuolar polyphosphate accumulation, microautophagy and non-autophagic vacuolar fusion; important regulator of substrate invagination from the vacuolar membrane; targeted to vacuole via AP-3 pathway; VTC2 has a paralog, VTC3, that arose from the whole genome duplication
codon start: 1
product: vacuolar transporter chaperone
translation: MLFGVKLANEVYPPWKGSYINYEGLKKFLKEDSVKDGSNDKKARWDDSDESKFVEELDKELEKVYGFQLKKYNNLMERLSHLEKQTDTEAAIKALDADAFQRVLEELLSESTELDNFKRLNFTGFAKIVKKHDKLYPKYPSVKSLLEVRLKELPSHSEEYSPLLYRISFLYNILRSNFNTASEPLASASKFSSIVSNDIDMNFRSFKFWVHNDNLMEVKTRILRHLPVLVYANVPSENDDLVNRFESDISNNDEIVGSSSSTSSVEHGLGARSFDPLINTLYFDNEHFELYNDKLLKLNSAPTLRLRWTGQLSDKPDIFLEKKTLIEDEATGKSEFDLTKLQLKQKFINGFIFEGDKKFKEQTLKKLKESGTAGRDLERLEEDFSEIQNFIIKNELQPVFRTVYTRTAFQIPGDDKIRVTIDSNIVFIKEDSFDRERPIRDPNTWHRTDIDANVANPLKFLRGGEYAKFPYSVMEIKVKSSLDSSMSASSMISNVKLPKKHGQWLNDLTNSHLVKEIPKFSIFVQGVASLYGDDEKLDILPFWLPDLETDIRQDPKQAYEEEKKKLLKQKEIQKKIDGMRRLSNLKEPQHQAAVPVSQEENERITSQGDLEADGSSDEETEQEPHSKRSKKVRRRKPKATFLRILAGRDPKLMGVDSEEEEIELPPGVKKPLNLLKNAGPVNVEAKVWLANERTFNRWLSVTSLLSVLTFSIYNSVKKAEYPTLANYMAYVYFGLTIFCALWSYSIYMKRVDIIQQRSGQHLDAPLGPVLVSIVLFVTLVVNFVMAFRNAAKSRQELQIQNLEVPERIPEVLRPLQNYLFKLMGPSSD
SIO_010081: YFL004W
subclass of: SO_0000673
so part of: YFL004W
location: 131810..134296
location: region:131810-134296:1
so has part: feature:131810-134296:1:exon

NP_116651.1
type: Protein
SIO_000068: ncbiprotein

S000001890
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:131810-134296:1:exon

YFL003C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MSH4
locus tag: YFL003C
so part of: sequence
location: complement(<134521..>137157)
location: region:134521-137157:-1
so has part: feature:134521-137157:-1:exon
subclass of: SO_0000010

850545
type: Gene
SIO_000068: ncbigene

position:134521:-1
position: 134521
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:137157:-1
position: 137157
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:134521-137157:-1:exon

YFL003C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MSH4
locus tag: YFL003C
product: MutS family protein MSH4
transcript id: NM_001179963.1
SIO_010081: YFL003C
subclass of: SO_0000673
so part of: YFL003C
location: complement(<134521..>137157)
location: region:134521-137157:-1
so has part: feature:134521-137157:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:134521-137157:-1:exon

YFL003C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MSH4
locus tag: YFL003C
experiment: EXISTENCE:direct assay:GO:0000228 nuclear chromosome [PMID:11454751]
experiment: EXISTENCE:direct assay:GO:0000400 four-way junction DNA binding [PMID:30467025]
experiment: EXISTENCE:direct assay:GO:0000403 Y-form DNA binding [PMID:30467025]
experiment: EXISTENCE:direct assay:GO:0003690 double-stranded DNA binding [PMID:30467025]
experiment: EXISTENCE:direct assay:GO:0062037 D-loop DNA binding [PMID:30467025]
experiment: EXISTENCE:mutant phenotype:GO:0007131 reciprocal meiotic recombination [PMID:11454751|PMID:18615017|PMID:7622037]
experiment: EXISTENCE:physical interaction:GO:0062128 MutSgamma complex [PMID:9374523]
note: Protein involved in meiotic recombination; required for normal levels of crossing over, colocalizes with Zip2p to discrete foci on meiotic chromosomes, has homology to bacterial MutS protein
codon start: 1
product: MutS family protein MSH4
translation: MSESNLSSFISTNYFNLRSAANSSNSISKPSTKKSIRNQKSPTNISSWALKKKTLQIAETTWENNEKDSTHSHYLMTGSMASRTATSLSRYSTNASLLGPSIDCVLCCIYEVPRDISTRIGLCIINCNTGQMYLSDFMDSQIYIRVVHKLQIYQPTEILIPSSSLAPTVSKLATMIKFNVAETVKIEEGSRKCFNSQDGLAAITKYLMDDTKKDLKIEEIIDKTFALCAASAAISYMEEIISKSSRNLNAFRKLRIQFEGTENTMLIDSKTVRGLELVENKLDKNGISLWKFLDTTSTKMGQRSLRNSILQPLTDRGSIEMRLEALEELKANDDLLQKLRLEMKSLPDLDKLFSRLLCINHSAIKPDQRINYVLLLKETLQSVKSLKDALNDQLIQSRLISETKKIFNNDAIMEIEKLINSCINEDCVWASSAIQLLNQRSYAVKSDSNGLLDVSRQIYKEVKEEFFREVEDLTAKNKINLDHNYDSARGFYLRIKRQEFTDDVATLPDVFISRTIKKNYIECTTLNIIKKNARLKEVMEEILLLSEETVDELLDKIATHISELFMIAEAVAILDLVCSFTYNLKENNYTIPIFTNNLLIRDSRHPLLEKVLKNFVPNTISSTKHSSSLQIITGCNMSGKSVYLKQVALICIMAQMGSGIPALYGSFPVFKRLHARVCNDSMELTSSNFGFEMKEMAYFLDDINTETLLILDELGRGSSIADGFCVSLAVTEHLLRTEATVFLSTHFQDIPKIMSKKPAVSHLHMDAVLLNDNSVKMNYQLTQKSVAIENSGIRVVKKIFNPDIIAEAYNIHSLLKIAKARTENEDSNGVVDQKTINQMKRIHNLVAILKECAGNEKEPLTLGKLKEINSDFIENFEE
SIO_010081: YFL003C
subclass of: SO_0000673
so part of: YFL003C
location: complement(134521..137157)
location: region:134521-137157:-1
so has part: feature:134521-137157:-1:exon

NP_116652.1
type: Protein
SIO_000068: ncbiprotein

S000001891
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:134521-137157:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS605; Autonomously replicating sequence on Chromosome VI; activated early in S phase in 27% of cell cycles; inactive during premeiotic S phase
so part of: sequence
location: 135985..136085
location: region:135985-136085:1
so has part: feature:135985-136085:1:region

S000007637
type: SGD
SIO_000068: sgd

position:135985:1
position: 135985
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:136085:1
position: 136085
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:135985-136085:1:region

YNCF0004C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCF0004C
so part of: sequence
location: complement(137486..137559)
location: region:137486-137559:-1
so has part: feature:137486-137559:-1:exon
subclass of: SO_0000663

850546
type: Gene
SIO_000068: ncbigene

position:137486:-1
position: 137486
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:137559:-1
position: 137559
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:137486-137559:-1:exon

YNCF0004C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCF0004C
product: tRNA-Asn
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Asparagine tRNA (tRNA-Asn), predicted by tRNAscan-SE analysis
SIO_010081: YNCF0004C
subclass of: SO_0000673
so part of: YNCF0004C
location: complement(137486..137559)
location: region:137486-137559:-1
so has part: feature:137486-137559:-1:exon

S000006669
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:137486-137559:-1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 137663..137912
location: region:137663-137912:1
so has part: feature:137663-137912:1:region

S000006925
type: SGD
SIO_000068: sgd

position:137663:1
position: 137663
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:137912:1
position: 137912
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:137663-137912:1:region

mobile_element
type: Mobile Element
subclass of: SO_0001037
RO_0002162: 559292
note: YFLWTy2-1; Ty2 element, LTR retrotransposon of the Copia (Pseudoviridae) group; contains co-transcribed genes TYA Gag and TYB Pol, encoding proteins involved in structure and function of virus-like particles, flanked by two direct repeats
mobile element type: retrotransposon:YFLWTy2-1
so part of: sequence
location: 137913..143871
location: region:137913-143871:1
so has part: feature:137913-143871:1:region

S000006930
type: SGD
SIO_000068: sgd

position:137913:1
position: 137913
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:143871:1
position: 143871
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:137913-143871:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty2 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 137913..138240
location: region:137913-138240:1
so has part: feature:137913-138240:1:region

S000006926
type: SGD
SIO_000068: sgd

position:138240:1
position: 138240
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:137913-138240:1:region

YFL002W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YFL002W-A
so part of: sequence
location: <138204..>143517
location: region:138204-143517:1
so has part: feature:138204-143517:1:exon
subclass of: SO_0000010

850548
type: Gene
SIO_000068: ncbigene

position:138204:1
position: 138204
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:143517:1
position: 143517
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:138204-143517:1:exon

YFL002W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YFL002W-A
product: gag-pol fusion protein
transcript id: NM_001180862.2
SIO_010081: YFL002W-A
subclass of: SO_0000673
so part of: YFL002W-A
location: <138204..>143517
location: region:138204-143517:1
so has part: feature:138204-143517:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:138204-143517:1:exon

YFL002W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YFL002W-A
EC number: 2.7.7.7
EC number: 2.7.7.49
EC number: 3.1.26.4
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:9448009]
ribosomal slippage: true
note: Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes
codon start: 1
product: gag-pol fusion protein
translation: MESQQLHQNPHSLHGSAYASVTSKEVPSNQDPLAVSASNLPEFDRDSTKVNSQQETTPGTSAVPENHHHVSPQPASVPPPQNGQYQQHGMMTPNKAMASNWAHYQQPSMMTCSHYQTSPAYYQPDPHYPLPQYIPPLSTSSPDPIDSQNQHSEVPQAETKVRNNVLPPHTLTSEENFSTWVKFYIRFLKNSNLGDIIPNDQGEIKSQMTYEEHAYIYNTFQAFAPFHLLPTWVKQILEINYADILTVLCKSVSKMQTNNQELKDWIALANLEYDGSTSADTFEITVSTIIQRLKENNINVSDRLACQLILKGLSGDFKYLRNQYRTKTNMKLSQLFAEIQLIYDENKIMNLNKPSQYKQHSEYKNVSRTSPNTTNTKVTTRNYHRTNSSKPRAAKAHNIATSSKFSRVNNDHINESTVSSQYLSDDNELSLGQQQKESKPTHTIDSNDELPDHLLIDSGASQTLVRSAHYLHHATPNSEINIVDAQKQDIPINAIGNLHFNFQNGTKTSIKALHTPNIAYDLLSLSELANQNITACFTRNTLERSDGTVLAPIVKHGDFYWLSKKYLIPSHISKLTINNVNKSKSVNKYPYPLIHRMLGHANFRSIQKSLKKNAVTYLKESDIEWSNASTYQCPDCLIGKSTKHRHVKGSRLKYQESYEPFQYLHTDIFGPVHHLPKSAPSYFISFTDEKTRFQWVYPLHDRREESILNVFTSILAFIKNQFNARVLVIQMDRGSEYTNKTLHKFFTNRGITACYTTTADSRAHGVAERLNRTLLNDCRTLLHCSGLPNHLWFSAVEFSTIIRNSLVSPKNDKSARQHAGLAGLDITTILPFGQPVIVNNHNPDSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQDKQSKLDQFNYDTLTFDDDLNRLTAHNQSFIEQNETEQSYDQNTESDHDYQSEIEINSDPLVNDFSSQSINPLQLDKEPVQKVRAPKEVDADISEYNILPSTIRSRTPHIINKESTEMGGTVESDTTSPRHSSTFTARNQNRPGSTNEMIDLTSQDRVNYGLENIKTTRLGGTEEPYIQRNSDTNIKYRTTNSTPSIDDRSSNSESTTPIISIETKAVCDNTPSIDTDPPEYRSSDHATPNIMPDKSSKNVTADSILDDLPLPDLTHKSPTDTSDVSKDIPHIHSRQTNSSLGGMDDSNVLTTTKSKKRSLEDNETEIEVSRDTWNNKNMRSLEPPRSKKRINLIAAIKGVKSIKPVRTTLRYDEAITYNKDNKEKDRYVEAYHKEISQLLKMNTWDTNKYYDRNDIDPKKVINSMFIFNKKRDGTHKARFVARGDIQHPDTYDSDMQSNTVHHYALMTSLSIALDNDYYITQLDISSAYLYADIKEELYIRPPPHLGLNDKLLRLRKSLYGLKQSGANWYETIKSYLINCCDMQEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRSKYMKLGMEKSLTEKLPKLNVPLNPKGKKLRAPGQPGHYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTKPDNKLVAISDASYGNQPYYKSQIGNIFLLNGKVIGGKSTKASLTCTSTTEAEIHAVSEAIPLLNNLSHLVQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYYIETKKNIADVMTKPLPIKTFKLLTNKWIH
SIO_010081: YFL002W-A
subclass of: SO_0000673
so part of: YFL002W-A
location: join(138204..139496,139498..143517)
location: region:138204-143517:1
so has part: feature:138204-139496:1:exon
so has part: feature:139498-143517:1:exon

NP_116653.1
type: Protein
SIO_000068: ncbiprotein

S000002962
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:138204-139496:1:exon

position:139496:1
position: 139496
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:139498-143517:1:exon

position:139498:1
position: 139498
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YFL002W-B
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YFL002W-B
so part of: sequence
location: <138204..>139520
location: region:138204-139520:1
so has part: feature:138204-139520:1:exon
subclass of: SO_0000010

850547
type: Gene
SIO_000068: ncbigene

position:139520:1
position: 139520
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:138204-139520:1:exon

YFL002W-B
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YFL002W-B
product: gag protein
transcript id: NM_001184430.1
SIO_010081: YFL002W-B
subclass of: SO_0000673
so part of: YFL002W-B
location: <138204..>139520
location: region:138204-139520:1
so has part: feature:138204-139520:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:138204-139520:1:exon

YFL002W-B
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YFL002W-B
note: Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag
codon start: 1
product: gag protein
translation: MESQQLHQNPHSLHGSAYASVTSKEVPSNQDPLAVSASNLPEFDRDSTKVNSQQETTPGTSAVPENHHHVSPQPASVPPPQNGQYQQHGMMTPNKAMASNWAHYQQPSMMTCSHYQTSPAYYQPDPHYPLPQYIPPLSTSSPDPIDSQNQHSEVPQAETKVRNNVLPPHTLTSEENFSTWVKFYIRFLKNSNLGDIIPNDQGEIKSQMTYEEHAYIYNTFQAFAPFHLLPTWVKQILEINYADILTVLCKSVSKMQTNNQELKDWIALANLEYDGSTSADTFEITVSTIIQRLKENNINVSDRLACQLILKGLSGDFKYLRNQYRTKTNMKLSQLFAEIQLIYDENKIMNLNKPSQYKQHSEYKNVSRTSPNTTNTKVTTRNYHRTNSSKPRAAKAHNIATSSKFSRVNNDHINESTVSSQYLSDDNELSLRPATERI
SIO_010081: YFL002W-B
subclass of: SO_0000673
so part of: YFL002W-B
location: 138204..139520
location: region:138204-139520:1
so has part: feature:138204-139520:1:exon

NP_058157.1
type: Protein
SIO_000068: ncbiprotein

S000007404
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:138204-139520:1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty2 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 143540..143871
location: region:143540-143871:1
so has part: feature:143540-143871:1:region

S000006927
type: SGD
SIO_000068: sgd

position:143540:1
position: 143540
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:143540-143871:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 143872..143947
location: region:143872-143947:1
so has part: feature:143872-143947:1:region

S000006928
type: SGD
SIO_000068: sgd

position:143872:1
position: 143872
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:143947:1
position: 143947
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:143872-143947:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty4 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 144203..144523
location: region:144203-144523:1
so has part: feature:144203-144523:1:region

S000006929
type: SGD
SIO_000068: sgd

position:144203:1
position: 144203
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:144523:1
position: 144523
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:144203-144523:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(144524..144822)
location: region:144524-144822:-1
so has part: feature:144524-144822:-1:region

S000006923
type: SGD
SIO_000068: sgd

position:144524:-1
position: 144524
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:144822:-1
position: 144822
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:144524-144822:-1:region

YFL002C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SPB4
locus tag: YFL002C
so part of: sequence
location: complement(<145114..>146934)
location: region:145114-146934:-1
so has part: feature:145114-146934:-1:exon
subclass of: SO_0000010

850549
type: Gene
SIO_000068: ncbigene

position:145114:-1
position: 145114
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:146934:-1
position: 146934
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:145114-146934:-1:exon

YFL002C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SPB4
locus tag: YFL002C
product: putative ATP-dependent RNA helicase SPB4
transcript id: NM_001179964.1
SIO_010081: YFL002C
subclass of: SO_0000673
so part of: YFL002C
location: complement(<145114..>146934)
location: region:145114-146934:-1
so has part: feature:145114-146934:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:145114-146934:-1:exon

YFL002C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SPB4
locus tag: YFL002C
EC number: 3.6.4.13
experiment: EXISTENCE:direct assay:GO:0005654 nucleoplasm [PMID:9769101]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:9769101|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0030686 90S preribosome [PMID:21825077]
experiment: EXISTENCE:direct assay:GO:0030687 preribosome, large subunit precursor [PMID:22735702]
experiment: EXISTENCE:mutant phenotype:GO:0000027 ribosomal large subunit assembly [PMID:21825077|PMID:2408148]
experiment: EXISTENCE:mutant phenotype:GO:0000470 maturation of LSU-rRNA [PMID:2408148]
experiment: EXISTENCE:mutant phenotype:GO:1902626 assembly of large subunit precursor of preribosome [PMID:22735702]
experiment: EXISTENCE:physical interaction:GO:0030686 90S preribosome [PMID:21825077]
note: Putative ATP-dependent RNA helicase; nucleolar protein required for synthesis of 60S ribosomal subunits at a late step in the pathway; sediments with 66S pre-ribosomes in sucrose gradients
codon start: 1
product: putative ATP-dependent RNA helicase SPB4
translation: MSKSLEWDNLGFSLLPWIRTGLDVMGFETMTPVQASTIPMLAGNKDVVVDSVTGSGKTAAFVIPVLEKVVKEEANTSKFKKAHFHSLIIAPTRELSRQIESVVLSFLEHYPSDLFPIKCQLLVGTNEATVRDDVSNFLRNRPQILIGTPGRVLDFLQMPAVKTSACSMVVMDEADRLLDMSFIKDTEKILRLLPKQRRTGLFSATMRSAGSDIFKTGLRNPVRITVNSKNQAPSSLKLNYCVVNPAEKLQLLVSILNNYKFKKCIVYFPTCVSVSYFYSFIQYLGKRNILVNEVEIFSLHGKLQTSARTKTLTAFTDSLSNSVLFTTDVAARGIDIPDVDLVIQLDPPTNTDMFMHRCGRTGRANRVGKAITFLNEGREEDFIPFMQVKNVELEELDLEVKGITTNFYEDFRNWILEDRDRFDKGVKAYVAFIKYYSNHSATSIFRLQSLDYVGIAKLYGLFRLPRMPEITKYLATEKQEGIFPGNWLVDPPVNMDEYKYKDKKREKERQETLKNISLINDKKKLKSELKKKNLAWSDKTLTKERKLERKEKMSLKRKAIEEELKAEELDENAEEERIKEDWKEIVLQNKRKKVSSKAIQGNFDDL
SIO_010081: YFL002C
subclass of: SO_0000673
so part of: YFL002C
location: complement(145114..146934)
location: region:145114-146934:-1
so has part: feature:145114-146934:-1:exon

NP_116654.1
type: Protein
SIO_000068: ncbiprotein

S000001894
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:145114-146934:-1:exon

YFL001W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: HRM3
alternative label: PUS3
gene: DEG1
locus tag: YFL001W
gene synonym: HRM3; PUS3
so part of: sequence
location: <147131..>148459
location: region:147131-148459:1
so has part: feature:147131-148459:1:exon
subclass of: SO_0000010

850550
type: Gene
SIO_000068: ncbigene

position:147131:1
position: 147131
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:148459:1
position: 148459
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:147131-148459:1:exon

YFL001W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: HRM3
alternative label: PUS3
gene: DEG1
locus tag: YFL001W
gene synonym: HRM3; PUS3
product: pseudouridine synthase DEG1
transcript id: NM_001179965.1
SIO_010081: YFL001W
subclass of: SO_0000673
so part of: YFL001W
location: <147131..>148459
location: region:147131-148459:1
so has part: feature:147131-148459:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:147131-148459:1:exon

YFL001W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: HRM3
alternative label: PUS3
gene: DEG1
locus tag: YFL001W
gene synonym: HRM3; PUS3
EC number: 5.4.99.45
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:9430663]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:9430663]
experiment: EXISTENCE:direct assay:GO:0009982 pseudouridine synthase activity [PMID:9430663]
experiment: EXISTENCE:direct assay:GO:0031119 tRNA pseudouridine synthesis [PMID:9430663]
experiment: EXISTENCE:mutant phenotype:GO:0009982 pseudouridine synthase activity [PMID:9430663]
experiment: EXISTENCE:mutant phenotype:GO:0031119 tRNA pseudouridine synthesis [PMID:9430663]
experiment: EXISTENCE:mutant phenotype:GO:1990481 mRNA pseudouridine synthesis [PMID:25192136]
note: tRNA:pseudouridine synthase; introduces pseudouridines at position 38 or 39 in tRNA; also responsible for pseudouracil modification of some mRNAs; important for maintenance of translation efficiency and normal cell growth, localizes to both the nucleus and cytoplasm; non-essential for viability
codon start: 1
product: pseudouridine synthase DEG1
translation: MSNFIRRLVGKMKAISTGTNAIVSKKDSIYANWSKEQLIRRITELENANKPHSEKFQHIEDNKKRKISQEEVTRSKAKKAPKKFDFSKHNTRFIALRFAYLGWNYNGLAVQKEYTPLPTVEGTILEAMNKCKLVPSMVLQDYKFSRCGRTDKGVSAMNQVISLEVRSNLTDEEQRDPTNDSREIPYVHVLNQLLPDDIRISAVCLRPPPNFDARFSCVHRHYKYIFNGKNLNIEKMSKAASYFVGERDFRNFCKLDGSKQITNFKRTIISSKILPLSETFYCFDLVGSAFLWHQVRCMMAILFLVGQSLEVPEIVLRLTDIEKTPQRPVYEMANDIPLLLYDCKFPEMDWQEPTVDDYKAIKFTTATEALTLHYELKAAVCNIFKDVLPTANTNNFSKTIINLGDGRGKVVGTYVKLEDRSVMEPVEVVNAKYSKKKNNKNK
SIO_010081: YFL001W
subclass of: SO_0000673
so part of: YFL001W
location: 147131..148459
location: region:147131-148459:1
so has part: feature:147131-148459:1:exon

NP_116655.1
type: Protein
SIO_000068: ncbiprotein

S000001895
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:147131-148459:1:exon

centromere
type: Centromere
subclass of: SO_0000577
RO_0002162: 559292
note: CEN6; Chromosome VI centromere
so part of: sequence
location: 148510..148627
location: region:148510-148627:1
so has part: feature:148510-148627:1:region

S000001896
type: SGD
SIO_000068: sgd

position:148510:1
position: 148510
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:148627:1
position: 148627
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:148510-148627:1:region

centromere
type: Centromere
subclass of: SO_0000577
RO_0002162: 559292
note: CEN6_CDEI of CEN6
so part of: sequence
location: 148510..148519
location: region:148510-148519:1
so has part: feature:148510-148519:1:region

position:148519:1
position: 148519
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:148510-148519:1:region

centromere
type: Centromere
subclass of: SO_0000577
RO_0002162: 559292
note: CEN6_CDEII of CEN6
so part of: sequence
location: 148520..148602
location: region:148520-148602:1
so has part: feature:148520-148602:1:region

position:148520:1
position: 148520
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:148602:1
position: 148602
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:148520-148602:1:region

centromere
type: Centromere
subclass of: SO_0000577
RO_0002162: 559292
note: CEN6_CDEIII of CEN6
so part of: sequence
location: 148603..148627
location: region:148603-148627:1
so has part: feature:148603-148627:1:region

position:148603:1
position: 148603
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:148603-148627:1:region

YFR001W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: LOC1
locus tag: YFR001W
so part of: sequence
location: <149110..>149724
location: region:149110-149724:1
so has part: feature:149110-149724:1:exon
subclass of: SO_0000010

850551
type: Gene
SIO_000068: ncbigene

position:149110:1
position: 149110
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:149724:1
position: 149724
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:149110-149724:1:exon

YFR001W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: LOC1
locus tag: YFR001W
product: Loc1p
transcript id: NM_001179966.1
SIO_010081: YFR001W
subclass of: SO_0000673
so part of: YFR001W
location: <149110..>149724
location: region:149110-149724:1
so has part: feature:149110-149724:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:149110-149724:1:exon

YFR001W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: LOC1
locus tag: YFR001W
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:11309412]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:16871394]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0017148 negative regulation of translation [PMID:31323064]
experiment: EXISTENCE:direct assay:GO:0030687 preribosome, large subunit precursor [PMID:11583614|PMID:27458021|PMID:17443350|PMID:23212245]
experiment: EXISTENCE:mutant phenotype:GO:0000055 ribosomal large subunit export from nucleus [PMID:16871394]
experiment: EXISTENCE:mutant phenotype:GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:16871394]
experiment: EXISTENCE:mutant phenotype:GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:16871394]
experiment: EXISTENCE:mutant phenotype:GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:16871394]
experiment: EXISTENCE:mutant phenotype:GO:0008298 intracellular mRNA localization [PMID:11309412]
experiment: EXISTENCE:mutant phenotype:GO:0042273 ribosomal large subunit biogenesis [PMID:11583614|PMID:27458021|PMID:31779129]
experiment: EXISTENCE:mutant phenotype:GO:0050821 protein stabilization [PMID:31779129]
experiment: EXISTENCE:mutant phenotype:GO:0101031 chaperone complex [PMID:31779129]
experiment: EXISTENCE:physical interaction:GO:0042273 ribosomal large subunit biogenesis [PMID:11583614]
note: Nucleolar protein involved in the asymmetric localization of ASH1 mRNA; binds cooperatively with She2p to the E3 zip-code element in the 3'-UTR of the mRNA; constituent of 66S pre-ribosomal particles involved in pre-rRNA processing and nuclear export of the 60S subunit; may facilitate Rpl43p loading; required post-transcriptionally for efficient retrotransposition; absence results in decreased Ty1 Gag:GFP protein levels; relocalizes from nucleus to cytoplasm upon DNA replication stress
codon start: 1
product: Loc1p
translation: MAPKKPSKRQNLRREVAPEVFQDSQARNQLANVPHLTEKSAQRKPSKTKVKKEQSLARLYGAKKDKKGKYSEKDLNIPTLNRAIVPGVKIRRGKKGKKFIADNDTLTLNRLITTIGDKYDDIAESKLEKARRLEEIRELKRKEIERKEALKQDKLEEKKDEIKKKSSVARTIRRKNKRDMLKSEAKASESKTEGRKVKKVSFAQ
SIO_010081: YFR001W
subclass of: SO_0000673
so part of: YFR001W
location: 149110..149724
location: region:149110-149724:1
so has part: feature:149110-149724:1:exon

NP_116656.1
type: Protein
SIO_000068: ncbiprotein

S000001897
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:149110-149724:1:exon

YFR002W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: NIC96
locus tag: YFR002W
so part of: sequence
location: <150016..>152535
location: region:150016-152535:1
so has part: feature:150016-152535:1:exon
subclass of: SO_0000010

850552
type: Gene
SIO_000068: ncbigene

position:150016:1
position: 150016
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:152535:1
position: 152535
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:150016-152535:1:exon

YFR002W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: NIC96
locus tag: YFR002W
product: linker nucleoporin NIC96
transcript id: NM_001179967.1
SIO_010081: YFR002W
subclass of: SO_0000673
so part of: YFR002W
location: <150016..>152535
location: region:150016-152535:1
so has part: feature:150016-152535:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:150016-152535:1:exon

YFR002W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: NIC96
locus tag: YFR002W
experiment: EXISTENCE:direct assay:GO:0005643 nuclear pore [PMID:10684247|PMID:7688296]
experiment: EXISTENCE:direct assay:GO:0044612 nuclear pore linkers [PMID:18046406]
experiment: EXISTENCE:direct assay:GO:0044615 nuclear pore nuclear basket [PMID:9813081]
experiment: EXISTENCE:mutant phenotype:GO:0000055 ribosomal large subunit export from nucleus [PMID:11071906]
experiment: EXISTENCE:mutant phenotype:GO:0006606 protein import into nucleus [PMID:12730220|PMID:7828598]
experiment: EXISTENCE:mutant phenotype:GO:0006999 nuclear pore organization [PMID:11121302|PMID:8682854]
experiment: EXISTENCE:mutant phenotype:GO:0017056 structural constituent of nuclear pore [PMID:18206968]
note: Linker nucleoporin component of the nuclear pore complex (NPC); also part of the NPC nuclear basket; contributes to nucleocytoplasmic transport and NPC biogenesis; forms stable associations with three FG-nucleoporins (Nsp1p, Nup57p, and Nup49p)
codon start: 1
product: linker nucleoporin NIC96
translation: MLETLRGNKLHSGTSKGANKKLNELLESSDNLPSASSELGSIQVSINELRRRVFQLRSKNKASKDYTKAHYLLANSGLSFEDVDAFIKDLQTNQFLEPNPPKIIESEELEFYIRTKKEENILMSIEQLLNGATKDFDNFINHNLNLDWAQHKNEVMKNFGILIQDKKTVDHKKSISSLDPKLPSWGNKGNNILNSNESRLNVNENNILREKFENYARIVFQFNNSRQANGNFDIANEFISILSSANGTRNAQLLESWKILESMKSKDINIVEVGKQYLEQQFLQYTDNLYKKNMNEGLATNVNKIKSFIDTKLKKADKSWKISNLTVINGVPIWALIFYLLRAGLIKEALQVLVENKANIKKVEQSFLTYFKAYASSKDHGLPVEYSTKLHTEYNQHIKSSLDGDPYRLAVYKLIGRCDLSRKNIPAVTLSIEDWLWMHLMLIKEKDAENDPVYERYSLEDFQNIIISYGPSRFSNYYLQTLLLSGLYGLAIDYTYTFSEMDAVHLAIGLASLKLFKIDSSTRLTKKPKRDIRFANILANYTKSFRYSDPRVAVEYLVLITLNEGPTDVELCHEALRELVLETKEFTVLLGKIGRDGARIPGVIEERQPLLHVRDEKEFLHTITEQAARRADEDGRIYDSILLYQLAEEYDIVITLVNSLLSDTLSASDLDQPLVGPDDNSETNPVLLARRMASIYFDNAGISRQIHVKNKEICMLLLNISSIRELYFNKQWQETLSQMELLDLLPFSDELSARKKAQDFSNLDDNIVKNIPNLLIITLSCISNMIHILNESKYQSSTKGQQIDSLKNVARQCMIYAGMIQYRMPRETYSTLINIDVSL
SIO_010081: YFR002W
subclass of: SO_0000673
so part of: YFR002W
location: 150016..152535
location: region:150016-152535:1
so has part: feature:150016-152535:1:exon

NP_116657.1
type: Protein
SIO_000068: ncbiprotein

S000001898
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:150016-152535:1:exon

YFR003C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: YPI1
locus tag: YFR003C
so part of: sequence
location: complement(<152657..>153124)
location: region:152657-153124:-1
so has part: feature:152657-153124:-1:exon
subclass of: SO_0000010

850553
type: Gene
SIO_000068: ncbigene

position:152657:-1
position: 152657
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:153124:-1
position: 153124
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:152657-153124:-1:exon

YFR003C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: YPI1
locus tag: YFR003C
product: type 1 protein phosphatase-activating protein YPI1
transcript id: NM_001179968.1
SIO_010081: YFR003C
subclass of: SO_0000673
so part of: YFR003C
location: complement(<152657..>153124)
location: region:152657-153124:-1
so has part: feature:152657-153124:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:152657-153124:-1:exon

YFR003C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: YPI1
locus tag: YFR003C
experiment: EXISTENCE:direct assay:GO:0004865 protein serine/threonine phosphatase inhibitor activity [PMID:14506263]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:17142459|PMID:18172024]
experiment: EXISTENCE:direct assay:GO:0032515 negative regulation of phosphoprotein phosphatase activity [PMID:14506263]
experiment: EXISTENCE:direct assay:GO:0035308 negative regulation of protein dephosphorylation [PMID:14506263]
experiment: EXISTENCE:direct assay:GO:1900180 regulation of protein localization to nucleus [PMID:18172024]
experiment: EXISTENCE:genetic interaction:GO:0007094 mitotic spindle assembly checkpoint signaling [PMID:18172024]
experiment: EXISTENCE:genetic interaction:GO:0032516 positive regulation of phosphoprotein phosphatase activity [PMID:18172024]
experiment: EXISTENCE:genetic interaction:GO:0072542 protein phosphatase activator activity [PMID:18172024]
experiment: EXISTENCE:mutant phenotype:GO:0004865 protein serine/threonine phosphatase inhibitor activity [PMID:14506263]
experiment: EXISTENCE:mutant phenotype:GO:0005977 glycogen metabolic process [PMID:14506263]
experiment: EXISTENCE:mutant phenotype:GO:0006873 cellular ion homeostasis [PMID:22367039]
experiment: EXISTENCE:mutant phenotype:GO:0032515 negative regulation of phosphoprotein phosphatase activity [PMID:14506263]
experiment: EXISTENCE:mutant phenotype:GO:0035308 negative regulation of protein dephosphorylation [PMID:14506263]
experiment: EXISTENCE:mutant phenotype:GO:1900180 regulation of protein localization to nucleus [PMID:17142459]
note: Regulatory subunit of the type I protein phosphatase (PP1) Glc7p; Glc7p participates in the regulation of a variety of metabolic processes including mitosis and glycogen metabolism; in vitro evidence suggests Ypi1p is an inhibitor of Glc7p while in vivo evidence suggests it is an activator; overproduction causes decreased cellular content of glycogen; partial depletion causes lithium sensitivity, while overproduction confers lithium-tolerance
codon start: 1
product: type 1 protein phosphatase-activating protein YPI1
translation: MSGNQMAMGSEQQQTVGSRTVSVEEVPAVLQLRATQDPPRSQEAMPTRHNVRWEENVIDNENMNKKKTKICCIFHPQNEDEEECNHHSDDDGSSSSGSSSSESENEKDLDFNERRQRRLERRHRKLEKKRSYSPNAYEIQPDYSEYRRKQQEKKD
SIO_010081: YFR003C
subclass of: SO_0000673
so part of: YFR003C
location: complement(152657..153124)
location: region:152657-153124:-1
so has part: feature:152657-153124:-1:exon

NP_116658.1
type: Protein
SIO_000068: ncbiprotein

S000001899
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:152657-153124:-1:exon

YFR004W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MPR1
gene: RPN11
locus tag: YFR004W
gene synonym: MPR1
so part of: sequence
location: <153393..>154313
location: region:153393-154313:1
so has part: feature:153393-154313:1:exon
subclass of: SO_0000010

850554
type: Gene
SIO_000068: ncbigene

position:153393:1
position: 153393
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:154313:1
position: 154313
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:153393-154313:1:exon

YFR004W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MPR1
gene: RPN11
locus tag: YFR004W
gene synonym: MPR1
product: proteasome regulatory particle lid subunit RPN11
transcript id: NM_001179969.1
SIO_010081: YFR004W
subclass of: SO_0000673
so part of: YFR004W
location: <153393..>154313
location: region:153393-154313:1
so has part: feature:153393-154313:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:153393-154313:1:exon

YFR004W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MPR1
gene: RPN11
locus tag: YFR004W
gene synonym: MPR1
EC number: 3.4.19.12
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:15210724]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:19773362]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:19773362]
experiment: EXISTENCE:direct assay:GO:0008541 proteasome regulatory particle, lid subcomplex [PMID:11742986|PMID:9741626]
experiment: EXISTENCE:direct assay:GO:0016579 protein deubiquitination [PMID:25389291]
experiment: EXISTENCE:direct assay:GO:0034515 proteasome storage granule [PMID:18504300]
experiment: EXISTENCE:direct assay:GO:0140492 metal-dependent deubiquitinase activity [PMID:25389291]
experiment: EXISTENCE:genetic interaction:GO:0016579 protein deubiquitination [PMID:14581483]
experiment: EXISTENCE:genetic interaction:GO:0043248 proteasome assembly [PMID:20941496]
experiment: EXISTENCE:mutant phenotype:GO:0000266 mitochondrial fission [PMID:19773362]
experiment: EXISTENCE:mutant phenotype:GO:0016559 peroxisome fission [PMID:19773362]
experiment: EXISTENCE:mutant phenotype:GO:0016579 protein deubiquitination [PMID:12183636]
experiment: EXISTENCE:mutant phenotype:GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process [PMID:12183636]
experiment: EXISTENCE:mutant phenotype:GO:0043248 proteasome assembly [PMID:20061387]
experiment: EXISTENCE:mutant phenotype:GO:0140492 metal-dependent deubiquitinase activity [PMID:12353037|PMID:12183636]
experiment: EXISTENCE:mutant phenotype:GO:1902906 proteasome storage granule assembly [PMID:23936414]
note: Metalloprotease subunit of 19S regulatory particle; part of 26S proteasome lid; couples the deubiquitination and degradation of proteasome substrates; involved, independent of catalytic activity, in fission of mitochondria and peroxisomes; protein abundance increases in response to DNA replication stress
codon start: 1
product: proteasome regulatory particle lid subunit RPN11
translation: MERLQRLMMNSKVGSADTGRDDTKETVYISSIALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLIDTGALINNLEPRQTTSNTGLLNKANIQALIHGLNRHYYSLNIDYHKTAKETKMLMNLHKEQWQSGLKMYDYEEKEESNLAATKSMVKIAEQYSKRIEEEKELTEEELKTRYVGRQDPKKHLSETADETLENNIVSVLTAGVNSVAIK
SIO_010081: YFR004W
subclass of: SO_0000673
so part of: YFR004W
location: 153393..154313
location: region:153393-154313:1
so has part: feature:153393-154313:1:exon

NP_116659.1
type: Protein
SIO_000068: ncbiprotein

S000001900
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:153393-154313:1:exon

YFR005C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SAD1
locus tag: YFR005C
so part of: sequence
location: complement(<154527..>155873)
location: region:154527-155873:-1
so has part: feature:154527-155873:-1:exon
subclass of: SO_0000010

850555
type: Gene
SIO_000068: ncbigene

position:154527:-1
position: 154527
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:155873:-1
position: 155873
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:154527-155873:-1:exon

YFR005C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SAD1
locus tag: YFR005C
product: mRNA splicing protein SAD1
transcript id: NM_001179970.1
SIO_010081: YFR005C
subclass of: SO_0000673
so part of: YFR005C
location: complement(<154527..>155873)
location: region:154527-155873:-1
so has part: feature:154527-155873:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:154527-155873:-1:exon

YFR005C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SAD1
locus tag: YFR005C
experiment: EXISTENCE:direct assay:GO:0000245 spliceosomal complex assembly [PMID:24681967]
experiment: EXISTENCE:direct assay:GO:0000398 mRNA splicing, via spliceosome [PMID:10022888]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:10022888]
note: Conserved zinc-finger domain protein involved in pre-mRNA splicing; critical for splicing of nearly all intron-containing genes; required for assembly of U4 snRNA into the U4/U6 particle
codon start: 1
product: mRNA splicing protein SAD1
translation: MEVDNKRRHSEDELKQEAVKKIKSQEPNYAYLETVVREKLDFDSEKICCITLSPLNVYCCLVCGHYYQGRHEKSPAFIHSIDENHHVFLNLTSLKFYMLPQNVQILHDGEVQLLNSIKFAAYPTYCPKDLEDFPRQCFDLSNRTYLNGFIGFTNAATYDYAHSVLLLISHMVPVRDHFLLNHFDNQGEFIKRLSICVKKIWSPKLFKHHLSVDDFVSYLKVREGLNLNPIDPRLFLLWLFNKICSSSNDLKSILNHSCKGKVKIAKVENKPEASESVTGKVIVKPFWVLTLDLPEFSPFEDGNSVDDLPQINITKLLTKFTKSRSSSTSTVFELTRLPQFLIFHFNRFDRNSDHPVKNRNQTLVEFSSELEILHVKYRLKANVVHVVIKQPSTDGNAFNGDEKSHWITQLYDNKSEKWIEIDGINTTEREAELLFLKETFIQVWEKQE
SIO_010081: YFR005C
subclass of: SO_0000673
so part of: YFR005C
location: complement(154527..155873)
location: region:154527-155873:-1
so has part: feature:154527-155873:-1:exon

NP_116660.1
type: Protein
SIO_000068: ncbiprotein

S000001901
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:154527-155873:-1:exon

YFR006W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YFR006W
so part of: sequence
location: <156145..>157752
location: region:156145-157752:1
so has part: feature:156145-157752:1:exon
subclass of: SO_0000010

850556
type: Gene
SIO_000068: ncbigene

position:156145:1
position: 156145
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:157752:1
position: 157752
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:156145-157752:1:exon

YFR006W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YFR006W
product: putative Xaa-Pro dipeptidase
transcript id: NM_001179971.1
SIO_010081: YFR006W
subclass of: SO_0000673
so part of: YFR006W
location: <156145..>157752
location: region:156145-157752:1
so has part: feature:156145-157752:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:156145-157752:1:exon

YFR006W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YFR006W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
note: Putative X-Pro aminopeptidase; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YFR006W is not an essential gene
codon start: 1
product: putative Xaa-Pro dipeptidase
translation: MCLEPISLVVFGSLVFFFGLVKYFKRGERQRTRGILQPEYKDKYYYSKEKGEEMGEVANVNEIPVKIRNHKYPAKEHNLRVKDLLLNRNPKLSKISTAFFIAGEELEGNKYCDTNKDFRQNRYFYHLSGVDIPASAILFNCSTDKLTLFLPNIDEEDVIWSGMPLSLDEAMRVFDIDEALYISDLGKKFKELQDFAIFTTDLDNVHDENIARSLIPSDPNFFYAMDETRAIKDWYEIESIRKACQISDKSHLAVMSALPIELNELQIQAEFEYHATRQGGRSLGYDPICCSGPACGTLHYVKNSEDIKGKHSILIDAGAEWRQYTSDITRCFPTSGKFTAEHREVYETVLDMQNQAMERIKPGAKWDDLHALTHKVLIKHFLSMGIFKKEFSEDEIFKRRASCAFYPHGLGHMLGLDVHDVGGNPNYDDPDPMFRYLRIRRPLKENMVITNEPGCYFNQFLIKEFLEKHPERLEVVDMSVLKRYMYVGGVRIEDDILVTKDGYENLTGITSDPDEIEKIVQKGLKKPRSGFHVIV
SIO_010081: YFR006W
subclass of: SO_0000673
so part of: YFR006W
location: 156145..157752
location: region:156145-157752:1
so has part: feature:156145-157752:1:exon

NP_116661.1
type: Protein
SIO_000068: ncbiprotein

S000001902
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:156145-157752:1:exon

YNCF0005C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCF0005C
so part of: sequence
location: complement(157916..158007)
location: region:157916-158007:-1
so has part: feature:157916-158007:-1:exon
subclass of: SO_0000663

850557
type: Gene
SIO_000068: ncbigene

position:157916:-1
position: 157916
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:158007:-1
position: 158007
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:157916-158007:-1:exon

YNCF0005C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCF0005C
product: tRNA-Phe
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Phenylalanine tRNA (tRNA-Phe), predicted by tRNAscan-SE analysis
SIO_010081: YNCF0005C
subclass of: SO_0000673
so part of: YNCF0005C
location: complement(join(157916..157951,157971..158007))
location: region:157916-158007:-1
so has part: feature:157971-158007:-1:exon
so has part: feature:157916-157951:-1:exon

S000006564
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:157971-158007:-1:exon

position:157971:-1
position: 157971
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:157916-157951:-1:exon

position:157951:-1
position: 157951
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 158376..158686
location: region:158376-158686:1
so has part: feature:158376-158686:1:region

S000006933
type: SGD
SIO_000068: sgd

position:158376:1
position: 158376
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:158686:1
position: 158686
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:158376-158686:1:region

YFR007W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: AIM12
gene: YFH7
locus tag: YFR007W
gene synonym: AIM12
so part of: sequence
location: <159299..>160360
location: region:159299-160360:1
so has part: feature:159299-160360:1:exon
subclass of: SO_0000010

850558
type: Gene
SIO_000068: ncbigene

position:159299:1
position: 159299
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:160360:1
position: 160360
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:159299-160360:1:exon

YFR007W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: AIM12
gene: YFH7
locus tag: YFR007W
gene synonym: AIM12
product: Yfh7p
transcript id: NM_001179972.1
SIO_010081: YFR007W
subclass of: SO_0000673
so part of: YFR007W
location: <159299..>160360
location: region:159299-160360:1
so has part: feature:159299-160360:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:159299-160360:1:exon

YFR007W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: AIM12
gene: YFH7
locus tag: YFR007W
gene synonym: AIM12
experiment: EXISTENCE:direct assay:GO:0016887 ATP hydrolysis activity [PMID:18004758]
note: Putative kinase with similarity to the PRK/URK/PANK kinase subfamily; the PRK/URK/PANK subfamily of P-loop kinases is also known as phosphoribulokinase/uridine kinase/bacterial pantothenate kinase
codon start: 1
product: Yfh7p
translation: MVDTHKLADDVLQLLDNRIEDNYRVCVILVGSPGSGKSTIAEELCQIINEKYHTFLSEHPNVIEVNDRLKPMVNLVDSLKTLQPNKVAEMIENQGLFKDHVEDVNFQPVKYSALTSNNEECTAVVARGGTANAIRIAAVDNPVNVNKLAQDSINIAQIVPMDGFHLSRRCLDLFKDPQTAHKRRGSPSTFDSNNFLQLCKILAKTSLCKVSSHHKFYSTSSVFEKLSKTFSQTIPDIFVPGFNHALKDPTPDQYCISKFTRIVILEGLYLLYDQENWKKIYKTLADTGALLVYKIDIDYEATEERVAKRHLQSGLVTTIAEGREKFRSNDLLNGRDIDNHLIKVDNIVHIRND
SIO_010081: YFR007W
subclass of: SO_0000673
so part of: YFR007W
location: 159299..160360
location: region:159299-160360:1
so has part: feature:159299-160360:1:exon

NP_116662.1
type: Protein
SIO_000068: ncbiprotein

S000001903
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:159299-160360:1:exon

YFR008W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FAR7
locus tag: YFR008W
so part of: sequence
location: <160535..>161200
location: region:160535-161200:1
so has part: feature:160535-161200:1:exon
subclass of: SO_0000010

850559
type: Gene
SIO_000068: ncbigene

position:160535:1
position: 160535
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:161200:1
position: 161200
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:160535-161200:1:exon

YFR008W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FAR7
locus tag: YFR008W
product: Far7p
transcript id: NM_001179973.1
SIO_010081: YFR008W
subclass of: SO_0000673
so part of: YFR008W
location: <160535..>161200
location: region:160535-161200:1
so has part: feature:160535-161200:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:160535-161200:1:exon

YFR008W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FAR7
locus tag: YFR008W
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:23625923]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0000321 re-entry into mitotic cell cycle after pheromone arrest [PMID:12588993]
note: Protein involved in recovery from pheromone-induced cell cycle arrest; acts in a Far1p-independent pathway; interacts with Far3p, Far8p, Far9p, Far10p, and Far11p; protein abundance increases in response to DNA replication stress
codon start: 1
product: Far7p
translation: MSDQINVLSMQQQQQQQQQQQQVYMSPQAENLNHMYLLVNKLVKQLRENQAEKAKILRNIDILSGSLNKYETSEEPHDTTENIALFNRFLEQRGKAPITEKEQLSNNLDENAKDDVMLGVLKRQNSMLRKSLQESKQVTLESMDLLSYSEDSLNYIVAQLRGNILMHHKETIKLIRQKFQTETIPLEDEEFKMYLENVNGLQKLTDISHTYRLLLRLHAQD
SIO_010081: YFR008W
subclass of: SO_0000673
so part of: YFR008W
location: 160535..161200
location: region:160535-161200:1
so has part: feature:160535-161200:1:exon

NP_116663.1
type: Protein
SIO_000068: ncbiprotein

S000001904
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:160535-161200:1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(161804..162135)
location: region:161804-162135:-1
so has part: feature:161804-162135:-1:region

S000006931
type: SGD
SIO_000068: sgd

position:161804:-1
position: 161804
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:162135:-1
position: 162135
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:161804-162135:-1:region

YNCF0006W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SUF20
locus tag: YNCF0006W
so part of: sequence
location: 162228..162298
location: region:162228-162298:1
so has part: feature:162228-162298:1:exon
subclass of: SO_0000663

850560
type: Gene
SIO_000068: ncbigene

position:162228:1
position: 162228
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:162298:1
position: 162298
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:162228-162298:1:exon

YNCF0006W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
gene: SUF20
locus tag: YNCF0006W
product: tRNA-Gly
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
experiment: EXISTENCE:direct assay:GO:0030371 translation repressor activity [PMID:27609601]
experiment: EXISTENCE:direct assay:GO:0043022 ribosome binding [PMID:27609601]
experiment: EXISTENCE:direct assay:GO:0043555 regulation of translation in response to stress [PMID:27609601]
note: Glycine tRNA (tRNA-Gly), predicted by tRNAscan-SE analysis; can mutate to suppress +1 frameshift mutations in glycine codons
SIO_010081: YNCF0006W
subclass of: SO_0000673
so part of: YNCF0006W
location: 162228..162298
location: region:162228-162298:1
so has part: feature:162228-162298:1:exon

S000006579
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:162228-162298:1:exon

YFR009W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GCN20
locus tag: YFR009W
so part of: sequence
location: <162488..>164746
location: region:162488-164746:1
so has part: feature:162488-164746:1:exon
subclass of: SO_0000010

850561
type: Gene
SIO_000068: ncbigene

position:162488:1
position: 162488
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:164746:1
position: 164746
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:162488-164746:1:exon

YFR009W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GCN20
locus tag: YFR009W
product: putative AAA family ATPase GCN20
transcript id: NM_001179974.1
SIO_010081: YFR009W
subclass of: SO_0000673
so part of: YFR009W
location: <162488..>164746
location: region:162488-164746:1
so has part: feature:162488-164746:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:162488-164746:1:exon

YFR009W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GCN20
locus tag: YFR009W
experiment: EXISTENCE:direct assay:GO:0022626 cytosolic ribosome [PMID:9234705]
experiment: EXISTENCE:mutant phenotype:GO:0006448 regulation of translational elongation [PMID:9234705]
experiment: EXISTENCE:mutant phenotype:GO:0043335 protein unfolding [PMID:32320318]
note: Positive regulator of the Gcn2p kinase activity; important for disaggregation of ordered and disordered protein aggregates; forms a complex with Gcn1p; proposed to stimulate Gcn2p activation by an uncharged tRNA; suppresses frameshifting at stalled ribosomes
codon start: 1
product: putative AAA family ATPase GCN20
translation: MASIGSQVRKAASSIDPIVTDYAVGYFNHLSGITFDAVQSKQVDLSTEVQFVSDLLIDAGASKAKVKELSESILKQLTTQLKENEAKLELTGDTSKRLLDINVLKSHNSKSDINVSLSMLGVNGDIEHTGRKMETRVDLKKLAKAEQKIAKKVAKRNNKFVKYEASKLINDQKEEDYDSFFLQINPLEFGSSAGKSKDIHIDTFDLYVGDGQRILSNAQLTLSFGHRYGLVGQNGIGKSTLLRALSRRELNVPKHVSILHVEQELRGDDTKALQSVLDADVWRKQLLSEEAKINERLKEMDVLRQEFEEDSLEVKKLDNEREDLDNHLIQISDKLVDMESDKAEARAASILYGLGFSTEAQQQPTNSFSGGWRMRLSLARALFCQPDLLLLDEPSNMLDVPSIAYLAEYLKTYPNTVLTVSHDRAFLNEVATDIIYQHNERLDYYRGQDFDTFYTTKEERRKNAQREYDNQMVYRKHLQEFIDKYRYNAAKSQEAQSRIKKLEKLPVLEPPEQDKTIDFKFPECDKLSPPIIQLQDVSFGYDENNLLLKDVNLDVQMDSRIALVGANGCGKTTLLKIMMEQLRPLKGFVSRNPRLRIGYFTQHHVDSMDLTTSAVDWMSKSFPGKTDEEYRRHLGSFGITGTLGLQKMQLLSGGQKSRVAFAALCLNNPHILVLDEPSNHLDTTGLDALVEALKNFNGGVLMVSHDISVIDSVCKEIWVSEQGTVKRFEGTIYDYRDYILQSADAAGVVKKH
SIO_010081: YFR009W
subclass of: SO_0000673
so part of: YFR009W
location: 162488..164746
location: region:162488-164746:1
so has part: feature:162488-164746:1:exon

NP_116664.1
type: Protein
SIO_000068: ncbiprotein

S000001905
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:162488-164746:1:exon

YFR010W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: UBP6
locus tag: YFR010W
so part of: sequence
location: <165067..>166566
location: region:165067-166566:1
so has part: feature:165067-166566:1:exon
subclass of: SO_0000010

850562
type: Gene
SIO_000068: ncbigene

position:165067:1
position: 165067
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:166566:1
position: 166566
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:165067-166566:1:exon

YFR010W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: UBP6
locus tag: YFR010W
product: ubiquitin-specific protease UBP6
transcript id: NM_001179975.1
SIO_010081: YFR010W
subclass of: SO_0000673
so part of: YFR010W
location: <165067..>166566
location: region:165067-166566:1
so has part: feature:165067-166566:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:165067-166566:1:exon

YFR010W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: UBP6
locus tag: YFR010W
EC number: 3.4.19.12
experiment: EXISTENCE:direct assay:GO:0000502 proteasome complex [PMID:12408819]
experiment: EXISTENCE:direct assay:GO:0004843 cysteine-type deubiquitinase activity [PMID:12408819|PMID:17018280]
experiment: EXISTENCE:direct assay:GO:0005838 proteasome regulatory particle [PMID:11029046]
experiment: EXISTENCE:genetic interaction:GO:0016579 protein deubiquitination [PMID:14581483]
experiment: EXISTENCE:mutant phenotype:GO:0004843 cysteine-type deubiquitinase activity [PMID:12408819|PMID:17018280]
experiment: EXISTENCE:mutant phenotype:GO:0016579 protein deubiquitination [PMID:12408819]
experiment: EXISTENCE:mutant phenotype:GO:0072671 mitochondria-associated ubiquitin-dependent protein catabolic process [PMID:21070972]
experiment: EXISTENCE:mutant phenotype:GO:1901799 negative regulation of proteasomal protein catabolic process [PMID:17018280]
note: Ubiquitin-specific protease; situated in the base subcomplex of the 26S proteasome, releases free ubiquitin from branched polyubiquitin chains en bloc, rather than from the distal tip of the chain; negatively regulates degradation of ubiquitinated proteins by the proteasome; works in opposition to Hul5p polyubiquitin elongation activity; mutant has aneuploidy tolerance; human homolog UBP14 complements yeast null mutant
codon start: 1
product: ubiquitin-specific protease UBP6
translation: MSGETFEFNIRHSGKVYPITLSTDATSADLKSKAEELTQVPSARQKYMVKGGLSGEESIKIYPLIKPGSTVMLLGTPDANLISKPAKKNNFIEDLAPEQQVQQFAQLPVGFKNMGNTCYLNATLQALYRVNDLRDMILNYNPSQGVSNSGAQDEEIHKQIVIEMKRCFENLQNKSFKSVLPIVLLNTLRKCYPQFAERDSQGGFYKQQDAEELFTQLFHSMSIVFGDKFSEDFRIQFKTTIKDTANDNDITVKENESDSKLQCHISGTTNFMRNGLLEGLNEKIEKRSDLTGANSIYSVEKKISRLPKFLTVQYVRFFWKRSTNKKSKILRKVVFPFQLDVADMLTPEYAAEKVKVRDELRKVEKEKNEKEREIKRRKFDPSSSENVMTPREQYETQVALNESEKDQWLEEYKKHFPPNLEKGENPSCVYNLIGVITHQGANSESGHYQAFIRDELDENKWYKFNDDKVSVVEKEKIESLAGGGESDSALILMYKGFGL
SIO_010081: YFR010W
subclass of: SO_0000673
so part of: YFR010W
location: 165067..166566
location: region:165067-166566:1
so has part: feature:165067-166566:1:exon

NP_116665.1
type: Protein
SIO_000068: ncbiprotein

S000001906
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:165067-166566:1:exon

YFR011C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: AIM13
alternative label: MCS19
gene: MIC19
locus tag: YFR011C
gene synonym: AIM13; MCS19
so part of: sequence
location: complement(<166746..>167258)
location: region:166746-167258:-1
so has part: feature:166746-167258:-1:exon
subclass of: SO_0000010

850563
type: Gene
SIO_000068: ncbigene

position:166746:-1
position: 166746
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:167258:-1
position: 167258
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:166746-167258:-1:exon

YFR011C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: AIM13
alternative label: MCS19
gene: MIC19
locus tag: YFR011C
gene synonym: AIM13; MCS19
product: Mic19p
transcript id: NM_001179976.1
SIO_010081: YFR011C
subclass of: SO_0000673
so part of: YFR011C
location: complement(<166746..>167258)
location: region:166746-167258:-1
so has part: feature:166746-167258:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:166746-167258:-1:exon

YFR011C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: AIM13
alternative label: MCS19
gene: MIC19
locus tag: YFR011C
gene synonym: AIM13; MCS19
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095|PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0044284 mitochondrial crista junction [PMID:22009199]
experiment: EXISTENCE:direct assay:GO:0061617 MICOS complex [PMID:21944719|PMID:21987634|PMID:22009199]
experiment: EXISTENCE:mutant phenotype:GO:0042407 cristae formation [PMID:21944719|PMID:21987634|PMID:22009199]
note: Component of the MICOS complex; MICOS (formerly MINOS or MitOS) is a mitochondrial inner membrane complex that extends into the intermembrane space and has a role in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane; Mic19p is peripheral to the inner membrane and may connect Mic60p with the Mic10p-Mic12p-Mic27p subcomplex; both yeast and human Mic19p become oxidized, and oxidation may regulate MICOS
codon start: 1
product: Mic19p
translation: MGSNTSKVGAGAEKQQVYTPLTQIDFSQSLVSQLDSSKESDYVTKQNAEKFIEKKVSQRLSNLEVETLKKFEDTLNNSLLSDDDKDAVDGISSSSLNNQIESLNKKLTLFDQLELQKLEKYGGAKGKSDKKTDNGSISIKAKLTECLLANKGKPLNCYEEMEEFKKLVMG
SIO_010081: YFR011C
subclass of: SO_0000673
so part of: YFR011C
location: complement(166746..167258)
location: region:166746-167258:-1
so has part: feature:166746-167258:-1:exon

NP_116666.1
type: Protein
SIO_000068: ncbiprotein

S000001907
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:166746-167258:-1:exon

YNCF0007W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SUP11
locus tag: YNCF0007W
so part of: sequence
location: 167437..167525
location: region:167437-167525:1
so has part: feature:167437-167525:1:exon
subclass of: SO_0000663

850564
type: Gene
SIO_000068: ncbigene

position:167437:1
position: 167437
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:167525:1
position: 167525
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:167437-167525:1:exon

YNCF0007W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
gene: SUP11
locus tag: YNCF0007W
product: tRNA-Tyr
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Tyrosine tRNA (tRNA-Tyr), predicted by tRNAscan-SE analysis; can mutate to suppress ochre nonsense mutations
SIO_010081: YNCF0007W
subclass of: SO_0000673
so part of: YNCF0007W
location: join(167437..167475,167490..167525)
location: region:167437-167525:1
so has part: feature:167437-167475:1:exon
so has part: feature:167490-167525:1:exon

S000006779
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:167437-167475:1:exon

position:167475:1
position: 167475
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:167490-167525:1:exon

position:167490:1
position: 167490
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS606; Highly-efficient autonomously replicating sequence on Chromosome VI; activated early in S phase in 74% of cell cycles; replication capacity dependent upon Sum1p
so part of: sequence
location: 167547..167801
location: region:167547-167801:1
so has part: feature:167547-167801:1:region

S000007638
type: SGD
SIO_000068: sgd

position:167547:1
position: 167547
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:167801:1
position: 167801
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:167547-167801:1:region

YFR012W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: DCV1
locus tag: YFR012W
so part of: sequence
location: <167888..>168496
location: region:167888-168496:1
so has part: feature:167888-168496:1:exon
subclass of: SO_0000010

850565
type: Gene
SIO_000068: ncbigene

position:167888:1
position: 167888
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:168496:1
position: 168496
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:167888-168496:1:exon

YFR012W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: DCV1
locus tag: YFR012W
product: Dcv1p
transcript id: NM_001179977.1
SIO_010081: YFR012W
subclass of: SO_0000673
so part of: YFR012W
location: <167888..>168496
location: region:167888-168496:1
so has part: feature:167888-168496:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:167888-168496:1:exon

YFR012W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: DCV1
locus tag: YFR012W
experiment: EXISTENCE:direct assay:GO:0005635 nuclear envelope [PMID:33002606]
note: hypothetical protein; deletion mutant shows strong genetic interaction with cdc28-as1 mutant in the presence of 1-NM-PP1; DCV1 has a paralog, YOL019W, that arose from the whole genome duplication
codon start: 1
product: Dcv1p
translation: MLNYKLILLFSSFLQLISFSGFMICCLTSPIIRNWGLAQAAGVSYGTFGYCKTLNSFSCSRVRLIYNTSKEILPGPSLERWWLSPKARHTIGGLLISIPVATCLTFISFALPLVIIFLFQTGGTNVSLITSNAILHILTLLSTIFACTVILLLCMHRDPVTISSLYDLVWLANCSLFPLLVIGVHFLSFRFDTSAQSDRKHS
SIO_010081: YFR012W
subclass of: SO_0000673
so part of: YFR012W
location: 167888..168496
location: region:167888-168496:1
so has part: feature:167888-168496:1:exon

NP_116667.1
type: Protein
SIO_000068: ncbiprotein

S000001908
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:167888-168496:1:exon

YFR012W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YFR012W-A
so part of: sequence
location: <169224..>169310
location: region:169224-169310:1
so has part: feature:169224-169310:1:exon
subclass of: SO_0000010

850566
type: Gene
SIO_000068: ncbigene

position:169224:1
position: 169224
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:169310:1
position: 169310
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:169224-169310:1:exon

YFR012W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YFR012W-A
product: uncharacterized protein
transcript id: NM_001184472.1
SIO_010081: YFR012W-A
subclass of: SO_0000673
so part of: YFR012W-A
location: <169224..>169310
location: region:169224-169310:1
so has part: feature:169224-169310:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:169224-169310:1:exon

YFR012W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YFR012W-A
note: hypothetical protein; identified by homology
codon start: 1
product: uncharacterized protein
translation: MLPRKYKPAYKKQAHRVKSNPQPAYTFQ
SIO_010081: YFR012W-A
subclass of: SO_0000673
so part of: YFR012W-A
location: 169224..169310
location: region:169224-169310:1
so has part: feature:169224-169310:1:exon

NP_076889.1
type: Protein
SIO_000068: ncbiprotein

S000007606
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:169224-169310:1:exon

YFR013W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: IOC3
locus tag: YFR013W
so part of: sequence
location: <169922..>172285
location: region:169922-172285:1
so has part: feature:169922-172285:1:exon
subclass of: SO_0000010

850567
type: Gene
SIO_000068: ncbigene

position:169922:1
position: 169922
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:172285:1
position: 172285
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:169922-172285:1:exon

YFR013W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: IOC3
locus tag: YFR013W
product: Ioc3p
transcript id: NM_001179978.1
SIO_010081: YFR013W
subclass of: SO_0000673
so part of: YFR013W
location: <169922..>172285
location: region:169922-172285:1
so has part: feature:169922-172285:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:169922-172285:1:exon

YFR013W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: IOC3
locus tag: YFR013W
experiment: EXISTENCE:curator inference:GO:0006338 chromatin remodeling [PMID:12482963]
experiment: EXISTENCE:direct assay:GO:0003677 DNA binding [PMID:12482963]
experiment: EXISTENCE:direct assay:GO:0016887 ATP hydrolysis activity [PMID:12482963]
experiment: EXISTENCE:direct assay:GO:0031491 nucleosome binding [PMID:12482963]
experiment: EXISTENCE:direct assay:GO:0036436 Isw1a complex [PMID:12482963]
experiment: EXISTENCE:mutant phenotype:GO:0007062 sister chromatid cohesion [PMID:27185881]
note: Subunit of the Isw1a complex; Isw1a has nucleosome-stimulated ATPase activity and represses transcription initiation by specific positioning of a promoter proximal dinucleosome; promotes nucleosome shifts in the 5 prime direction; IOC3 has a paralog, ESC8, that arose from the whole genome duplication
codon start: 1
product: Ioc3p
translation: MDSPSNSIQNLQQEAQGSSSAQLADHDHDRVSMAMPLQTDQSVSVSQSSDNLRRSRRVPKPRTSIYDEYEEELKERANKPKRKRPAPPKKKAPSTQNSKSNDKVEKKKTTSIAKDGKPTLKTNDKKVAPKPKPAHEQVEPALIPSNWTSVIPLLTSDFKNQYSVISRLKNPNMKPVPYAGDIIKLMAFINKFSSFFHSDLQNLSFQDFEVGLDLYPGDPNGSAAGIVKGPEDTSLLLYPDFMAIKDIVYCQDKMNLLFLSLLDLTFTENFDGKSAKKKGPLTTWENLKSSSKKVFSNPLYRLRLVAREWGYPREWRQQLPSDQDISKPKTALFEQDEQTPVVDPSHPEILTPNIYTWNANEPLPLESNPLYNREMDKNGILALKPMDRVVLLRALTDWCASHSSAIHDEIYKLTHGKKDPVFGIQTQQVPRYTIEGVDNTINQFKKLCSLIQSRYEIRSKKKHFVKQLKEGKKPDLSRKLEILKEIKAELKNAVKSEKDELLFSLYDKWVPLFEGELPDQPLANPFSERLYKLRLQEFFLGRVPHIGDFYMPRLHSYGDSLEMSTFTDLRNLQALLSKFKNNEYNAFTLFENDGQSMSAQFKLFYHDTPSLAHDVARGRNTSGKVYWYELCHDSATLLEFLEFLDYKIVKPQDEKKEGNEKEKEALNNEAHILEQKSTTDNNPSINTNPLPKDAKYNTARKKLQILKEFLSDYYFILRQFEQMKVQFADMKPGKRQLRRIQRQTVNYNTEYDSEEYVDDEEDDEADIYDDNDNDSSFDDGRVKRQRT
SIO_010081: YFR013W
subclass of: SO_0000673
so part of: YFR013W
location: 169922..172285
location: region:169922-172285:1
so has part: feature:169922-172285:1:exon

NP_116668.1
type: Protein
SIO_000068: ncbiprotein

S000001909
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:169922-172285:1:exon

YFR014C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CMK1
locus tag: YFR014C
so part of: sequence
location: complement(<172537..>173877)
location: region:172537-173877:-1
so has part: feature:172537-173877:-1:exon
subclass of: SO_0000010

850568
type: Gene
SIO_000068: ncbigene

position:172537:-1
position: 172537
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:173877:-1
position: 173877
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:172537-173877:-1:exon

YFR014C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CMK1
locus tag: YFR014C
product: calmodulin-dependent protein kinase CMK1
transcript id: NM_001179979.2
SIO_010081: YFR014C
subclass of: SO_0000673
so part of: YFR014C
location: complement(<172537..>173877)
location: region:172537-173877:-1
so has part: feature:172537-173877:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:172537-173877:-1:exon

YFR014C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CMK1
locus tag: YFR014C
EC number: 2.7.11.17
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:16319894]
experiment: EXISTENCE:direct assay:GO:0004683 calmodulin-dependent protein kinase activity [PMID:2061341]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:9756868]
experiment: EXISTENCE:mutant phenotype:GO:0007165 signal transduction [PMID:11743609]
note: Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication
codon start: 1
product: calmodulin-dependent protein kinase CMK1
translation: MDDKVSEKESSPKQTEEDSEGKMAHVQPASYVNKKKYVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSAFRAERVQDFLDECTTGEYPVKFHRPYWDSVSNKAKQFILKALNLDPSKRPTAAELLEDPWIICTELKTHNLLPGLKEGLDARQKFRNSVERVRLNMKIQKLRDLYLEQTESDSDFDEGSQANGSVPPLKATDTSQLSKKLSEEEQSKLKSELTSKAFAQLVNTVLAEKEKFLNINRVCSSDSDLPGSDIKSLDEAKEKPEGKDTKTEE
SIO_010081: YFR014C
subclass of: SO_0000673
so part of: YFR014C
location: complement(172537..173877)
location: region:172537-173877:-1
so has part: feature:172537-173877:-1:exon

NP_116669.1
type: Protein
SIO_000068: ncbiprotein

S000001910
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:172537-173877:-1:exon

YFR015C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GSY1
locus tag: YFR015C
so part of: sequence
location: complement(<174265..>176391)
location: region:174265-176391:-1
so has part: feature:174265-176391:-1:exon
subclass of: SO_0000010

850569
type: Gene
SIO_000068: ncbigene

position:174265:-1
position: 174265
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:176391:-1
position: 176391
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:174265-176391:-1:exon

YFR015C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GSY1
locus tag: YFR015C
product: glycogen (starch) synthase GSY1
transcript id: NM_001179980.1
SIO_010081: YFR015C
subclass of: SO_0000673
so part of: YFR015C
location: complement(<174265..>176391)
location: region:174265-176391:-1
so has part: feature:174265-176391:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:174265-176391:-1:exon

YFR015C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GSY1
locus tag: YFR015C
EC number: 2.4.1.11
experiment: EXISTENCE:direct assay:GO:0004373 glycogen (starch) synthase activity [PMID:2123485]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095|PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:mutant phenotype:GO:0005978 glycogen biosynthetic process [PMID:1908457]
note: Glycogen synthase; expression induced by glucose limitation, nitrogen starvation, environmental stress, and entry into stationary phase; GSY1 has a paralog, GSY2, that arose from the whole genome duplication; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress
codon start: 1
product: glycogen (starch) synthase GSY1
translation: MARDLQNHLLFEVATEVTNRVGGIYSVLKSKAPVTVAQYGDNYTLLGPLNKATYESEVEKLDWEDESIFPEELLPIQKTLMSMREKGVNFVYGNWLIEGAPRVILFELDSVRHFLNEWKADLWSLVGIPSPEHDHETNDAILLGYVVVWFLGEVSKLDSSHAIIGHFHEWLAGVALPLCRKKRIDVVTIFTTHATLLGRYLCAAGDVDFYNNLQYFDVDQEAGKRGIYHRYCIERAAAHTADVFTTVSQITALEAEHLLKRKPDGILPNGLNVVKFQAVHEFQNLHALKKDKINDFVRGHFHGCFDFDLDNTVYFFIAGRYEYKNKGADMFIESLARLNYRLKVSGSKKTVVAFLIMPAKTNSFTVEALKSQAIVKSLENTVNEVTASIGKRIFEHTMRYPHNGLESELPTNLDELLKSSEKVLLKKRVLALRRPYGELPPVVTHNMCDDANDPILNQIRHVRLFNDSSDRVKVIFHPEFLNANNPILGLDYDEFVRGCHLGVFPSYYEPWGYTPAECTVMGVPSITTNVSGFGAYMEDLIETDQAKDYGIYIVDRRFKSPDESVEQLADYMEEFVNKTRRQRINQRNRTERLSDLLDWKRMGLEYVKARQLGLRRAYPEQFKQLVGETISDANMNTLAGGKKFKIARPLSVPGSPKVRSNSTVYMTPGDLGTLQDANNADDYFNLSTNGAIDNDDDDNDTSAYYEDN
SIO_010081: YFR015C
subclass of: SO_0000673
so part of: YFR015C
location: complement(174265..176391)
location: region:174265-176391:-1
so has part: feature:174265-176391:-1:exon

NP_116670.1
type: Protein
SIO_000068: ncbiprotein

S000001911
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:174265-176391:-1:exon

YFR016C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: AIP5
locus tag: YFR016C
so part of: sequence
location: complement(<177042..>180743)
location: region:177042-180743:-1
so has part: feature:177042-180743:-1:exon
subclass of: SO_0000010

850570
type: Gene
SIO_000068: ncbigene

position:177042:-1
position: 177042
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:180743:-1
position: 180743
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:177042-180743:-1:exon

YFR016C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: AIP5
locus tag: YFR016C
product: Aip5p
transcript id: NM_001179981.1
SIO_010081: YFR016C
subclass of: SO_0000673
so part of: YFR016C
location: complement(<177042..>180743)
location: region:177042-180743:-1
so has part: feature:177042-180743:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:177042-180743:-1:exon

YFR016C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: AIP5
locus tag: YFR016C
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005933 cellular bud [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005934 cellular bud tip [PMID:31699995]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:31699995]
experiment: EXISTENCE:direct assay:GO:0032233 positive regulation of actin filament bundle assembly [PMID:31699995]
note: Protein that positively regulates actin assembly; forms a homodimer and interacts with G-actin; localization to the bud neck and bud tip requires Spa2p; YFR016C is not an essential gene
codon start: 1
product: Aip5p
translation: MVESLTVENQEHNVQPPSVTSAGDSYSTLATDLPLPSTNDIIESRDQLTESDLDEAINATENFAQELSSQRKSSKLKGHKKKNQGQIKANRDRDTIVKLSSSVGETEEASTRDAISHDLERKDDVIEIATDTINDATESPTQIPIDVNVVIKETSTNNVAEGTENVPPIKESTGIEVGNSPITRRKKNKKKKTTNRRGRNSSNPADTTDLSKQSTLDSILVGIEEYLQEDGSKNEDIKVNIVQDEPVNVEKMDIRTRNESSDKTFDIDVPNKDNVDETSSKSENNINEEKAEHTLPREENEILNVNEGNAASFKHQLEPHGLEAGDENGQASTKDVESESLTKNGFNFKENESKHLKAGEKQQTESDRDGISPSVLAKNQKETEIGKEDHVFEQKDKEDEKCRKELSVNHENNMSHNFNAAGSDSIIPPETERETYDDETMGPTKRISDNEKNLQHGTNDISVEVEKEEEEEEEEEENSTFSKVKKENVTGEQEAVRNNEVSGTEEESTSKGEEIMGGDEKQSEAGEKSSIIEIEGSANSAKISKDNLVLEDEAEAPTQENKPTEVVGEIDIPDAPRDDVEIVEAVEKNIIPEDLEVAKEDQEGEQVKLDEPVKAMKDDKIAMRGAESISEDMKKKQEGTAELSNEKAKKEVDETARESAEGVEVEKSKTPESPKVVKRCTSGRPEDLQINERDPEVLKEDVRVPDEDVKPEIATTIENSEEEDPKSQRVQISTEQAETTQKDMGDVGSTTSFKEEEKPKRFEITQEGDKITGKDTNHEHGEATEAASENSKASDVGTAEKYIEPSSESVKKDTEEDAEVENSEKTEFIKVKAELENLDAPKEAEVTAELNKENEDVEVDTEEDAEVENSEKTEFIKVKAELGNLDAPKEAEVTAELNKENEDVEVAATSKEDIETKCSEPAETPIEDGTCTEAEVSKKDAEAVTKEDENMENSKIAEALKDVTGDQEIDDINISDEFQRTVELPELEKQDIKDNKGEDKELEVEETEKETSLPDLVVEENITEEKNEIKQEEEEVSQLDFNETESISKEAPNNDENGFEDQSTRENPKKASADDIFKDILDETNEFLEQLKIVDDSELNALLQSLDAKDSTTQTTEQSKKNNDKPQDVITTSEIRKLNEKEPVYIYTSLAGGGFHMIPRTNRLSTILTANRIPFTYRDLGTDDEARKVWKTFSKGRSLPGVVRGHNDLIGNWEEIEEANEDYKLRELIYDTI
SIO_010081: YFR016C
subclass of: SO_0000673
so part of: YFR016C
location: complement(177042..180743)
location: region:177042-180743:-1
so has part: feature:177042-180743:-1:exon

NP_116671.1
type: Protein
SIO_000068: ncbiprotein

S000001912
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:177042-180743:-1:exon

YNCF0008C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCF0008C
so part of: sequence
location: complement(180974..181044)
location: region:180974-181044:-1
so has part: feature:180974-181044:-1:exon
subclass of: SO_0000663

850571
type: Gene
SIO_000068: ncbigene

position:180974:-1
position: 180974
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:181044:-1
position: 181044
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:180974-181044:-1:exon

YNCF0008C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCF0008C
product: tRNA-Gly
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
experiment: EXISTENCE:direct assay:GO:0030371 translation repressor activity [PMID:27609601]
experiment: EXISTENCE:direct assay:GO:0043022 ribosome binding [PMID:27609601]
experiment: EXISTENCE:direct assay:GO:0043555 regulation of translation in response to stress [PMID:27609601]
note: Glycine tRNA (tRNA-Gly), predicted by tRNAscan-SE analysis
SIO_010081: YNCF0008C
subclass of: SO_0000673
so part of: YNCF0008C
location: complement(180974..181044)
location: region:180974-181044:-1
so has part: feature:180974-181044:-1:exon

S000006580
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:180974-181044:-1:exon

YFR017C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: IGD1
locus tag: YFR017C
so part of: sequence
location: complement(<182274..>182861)
location: region:182274-182861:-1
so has part: feature:182274-182861:-1:exon
subclass of: SO_0000010

850572
type: Gene
SIO_000068: ncbigene

position:182274:-1
position: 182274
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:182861:-1
position: 182861
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:182274-182861:-1:exon

YFR017C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: IGD1
locus tag: YFR017C
product: Igd1p
transcript id: NM_001179982.1
SIO_010081: YFR017C
subclass of: SO_0000673
so part of: YFR017C
location: complement(<182274..>182861)
location: region:182274-182861:-1
so has part: feature:182274-182861:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:182274-182861:-1:exon

YFR017C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: IGD1
locus tag: YFR017C
experiment: EXISTENCE:direct assay:GO:0004857 enzyme inhibitor activity [PMID:21585652]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0004857 enzyme inhibitor activity [PMID:21585652]
experiment: EXISTENCE:mutant phenotype:GO:0045818 negative regulation of glycogen catabolic process [PMID:21585652]
note: Cytoplasmic protein that inhibits Gdb1p glycogen debranching activity; required for normal intracellular accumulation of glycogen; phosphorylated in vivo; expression increases during wine fermentation; protein abundance increases in response to DNA replication stress; IGD1 has a paralog, YOL024W, that arose from the whole genome duplication
codon start: 1
product: Igd1p
translation: MTDPHLNTPQVSTSPTFERSQDFLNIDEPPCAQETPSVSTFNLPGPSAPAQSVDKPVPMIRRRSTNYMDALNSREQARERESSIGEHAPGAERRSSGPMDFQNTIHNMQYRTTNDSDLSHAGVDMGDSISHTPICSRAGNRPIFKNSYLDNNSNGNSARVPHGSPPQLGTRRKSSFKYEDFKKDIYNQLHMFGEK
SIO_010081: YFR017C
subclass of: SO_0000673
so part of: YFR017C
location: complement(182274..182861)
location: region:182274-182861:-1
so has part: feature:182274-182861:-1:exon

NP_116672.1
type: Protein
SIO_000068: ncbiprotein

S000001913
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:182274-182861:-1:exon

YFR018C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YFR018C
so part of: sequence
location: complement(<183131..>184222)
location: region:183131-184222:-1
so has part: feature:183131-184222:-1:exon
subclass of: SO_0000010

850573
type: Gene
SIO_000068: ncbigene

position:183131:-1
position: 183131
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:184222:-1
position: 184222
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:183131-184222:-1:exon

YFR018C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YFR018C
product: uncharacterized protein
transcript id: NM_001179983.1
SIO_010081: YFR018C
subclass of: SO_0000673
so part of: YFR018C
location: complement(<183131..>184222)
location: region:183131-184222:-1
so has part: feature:183131-184222:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:183131-184222:-1:exon

YFR018C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YFR018C
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
note: hypothetical protein; SWAT-GFP and seamless GFP fusion proteins localize to the endoplasmic reticulum and mCherry fusion protein localizes to the vacuole
codon start: 1
product: uncharacterized protein
translation: MGMKYVLPLRLIGLAYLLVLFQVHRVTGWELSYEQYHAAHLNEAINPDSGWNKSTKNLLLPFNRTRVPGSEGSREIQRFIIEHFNNTLAGEWAVETQAFEENGYRFNNLVMTLQNNASEYLVLAAHYDTKIAPTGMVGAIDSAASCAALLYTAQFLTHIACHERTKEYNDLESNTVVSNSTLGVKIVFFDGEEAIEEWGPEDSIYGARRLAAQWLADGTMTRIRLLFLLDLLGSGEEEPLVPSYYAETHQEYQLLNRIEDDLLFRRGDEINGESALAAEVARQRKHLDPTDYRFLGLGHSVIGDDHTPFLAAGVPVLHAIPLPFPSTWHTVDDDFRHLDAAETRHWALLVCEFVVQSLRSRNQ
SIO_010081: YFR018C
subclass of: SO_0000673
so part of: YFR018C
location: complement(183131..184222)
location: region:183131-184222:-1
so has part: feature:183131-184222:-1:exon

NP_116673.1
type: Protein
SIO_000068: ncbiprotein

S000001914
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:183131-184222:-1:exon

YFR019W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SVL7
gene: FAB1
locus tag: YFR019W
gene synonym: SVL7
so part of: sequence
location: <184502..>191338
location: region:184502-191338:1
so has part: feature:184502-191338:1:exon
subclass of: SO_0000010

850574
type: Gene
SIO_000068: ncbigene

position:184502:1
position: 184502
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:191338:1
position: 191338
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:184502-191338:1:exon

YFR019W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SVL7
gene: FAB1
locus tag: YFR019W
gene synonym: SVL7
product: 1-phosphatidylinositol-3-phosphate 5-kinase
transcript id: NM_001179984.2
SIO_010081: YFR019W
subclass of: SO_0000673
so part of: YFR019W
location: <184502..>191338
location: region:184502-191338:1
so has part: feature:184502-191338:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:184502-191338:1:exon

YFR019W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SVL7
gene: FAB1
locus tag: YFR019W
gene synonym: SVL7
EC number: 2.7.1.150
experiment: EXISTENCE:direct assay:GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity [PMID:9811604]
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:11889142|PMID:9763421]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0010008 endosome membrane [PMID:11889142|PMID:9763421]
experiment: EXISTENCE:direct assay:GO:0032266 phosphatidylinositol-3-phosphate binding [PMID:9702203]
experiment: EXISTENCE:direct assay:GO:0046854 phosphatidylinositol phosphate biosynthetic process [PMID:9811604]
experiment: EXISTENCE:direct assay:GO:0070772 PAS complex [PMID:19037259]
experiment: EXISTENCE:mutant phenotype:GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity [PMID:9763421|PMID:9811604]
experiment: EXISTENCE:mutant phenotype:GO:0046854 phosphatidylinositol phosphate biosynthetic process [PMID:9763421|PMID:9811604]
experiment: EXISTENCE:physical interaction:GO:0070772 PAS complex [PMID:19037259]
note: 1-phosphatidylinositol-3-phosphate 5-kinase; vacuolar membrane kinase that generates phosphatidylinositol (3,5)P2, which is involved in vacuolar sorting and homeostasis
codon start: 1
product: 1-phosphatidylinositol-3-phosphate 5-kinase
translation: MSSEEPHASISFPDGSHVRSSSTGTSSVNTIDATLSRPNYIKKPSLHIMSTSTTSTTTDLVTNPILSNISVPKISPPTSSSIATATSTSHVTGTASHSNIKANANTSTSVNKKNLPPTTSGRIPSSTIKRYPSRYKPSHSLQLPIKNDSNFKRSSIYASKSTVTAIPIRNNRPISMQNSYARTPDSDHDDVGDEVSSIKSASSSLTASLSKSFLFAFYNNRKKDKTSNNGVLSKEYWMKDESSKECFSCGKTFNTFRRKHHCRICGQIFCSSCTLLIDGDRFGCHAKMRVCYNCYEHADTYEDSSDEENDSTMQLNEPRSRSRSRSSNTNPYSHSHSHLHLISQDNHNGTDLHDPVAATDNPQQQNEVYLLNDDDVQSIMTSGEDSKLFISTPPPPPKMAIPATKQGGSLEISFDSENDRALHYQDDNPGRHHHLDSVPTRYTIRDMDNISHYDTNSNSTLRPHYNTNNSTITINNLNNTTSNNSNYNNTNSNSNINNPAHSLRRSIFHYVSSNSVNKDSNNSSATPASSAQSSSILDPANRIIGNYAHRNYKFKFNYNSKGPSQQNDTANGNNDNNNNNNNNNNNNNNNSASGIADNNNIPSNDNGTTFTLDKKKRNPLTKSKSTSAYLEYPLNEEDSSEDEGSMSIYSVLNDDHKTDNPIRSMRNSTKSFQRAQASLQRMRFRRKSKSKHFPNNSKSSIYRDLNFLTNSTPNLLSVVSDDNLYDDSSPLQDKASSSAASRLTDRKFSNSSGSNNNSNSNSNINTDPWKRIASISGFKLKKEKKRELNEVSLLHMHALLKQLLNDQEISNLQEWITLLDGALRKVLRTILNARDLNTLDFRQTYVKIKRISGGSPQNSEYIDGVVFSKALPSKTMPRHLKNPRILLIMFPLEYQKNNNHFLSIESVFRQEREYLDKLVSRLKSLHPDIIYVGANVSGYALELLNDSGIVVQFNMKPQVIERIAKLTEADIAISVDKLATNIKMGECETFEVKSYIYGNISKTYTFLRGCNPELGGTILLRGDSLENLRKIKQVSEFMVYAIFSLKLESSFFNDNFIQLSTDVYLKRAESKKLQVFEGYFADFLIKFNNRILTVSPTVDFPIPFLLEKARGLEKKLIERINQYESESDLDRQTQLNMLQGLESTITKKHLGNLIKFLHEMEIENLELEFQKRSRQWEVSYSSSQNLLGTGSHQSITVLYSMVSTKTATPCVGPQIVTIDYFWDSDISIGQFIENVVGTARYPCQQGCNGLYLDHYRSYVHGSGKVDVLIEKFQTRLPKLKDIILTWSYCKKCGTSTPILQISEKTWNHSFGKYLEVMFWSYKDSVTGIGKCPHDFTKDHVKYFGYNDLVVRLEYSDLEVHELITPPRKIKWKPHIDIKLKVELYYKILEKINNFYGSVLSRLERIKLDSMTKDKVLSGQAKIIELKSNATEEQKLMLQDLDTFYADSPCDQHLPLNLVIKSLYDKAVNWNSTFAIFAKSYLPSETDISRITAKQLKKLFYDSSRKDSEDKKSLHDEKAKTRKPEKNELPLEGLKDVEKPKIDSKNTTENRDRTNEPQNAVTITTFKDDTPIIPTSGTSHLTVTPSASSVSSSLTPQTEERPPISRSGTGISMTHDKSTRPNIRKMSSDSSLCGLASLANEYSKNNKVSKLATFFDQMHFDALSKEFELERERERLQLNKDKYQAIRLQTSTPIVEIYKNVKDAVDEPLHSRSSGNNLSSANVKTLEAPVGEHSRANNCNPPNLDQNLETELENSISQWGENILNPSGKTTASTHLNSKPVVKETSENPKSIVRESDNSKSEPLPPVITTTTVNKVESTPQPEKSLLMKTLSNFWADRSAYLWKPLVYPTCPSEHIFTDSDVIIREDEPSSLIAFCLSTSDYRNKMMNLNVQQQQQQQTAEAAPAKTGGNSGGTTQTGDPSVNISPSVSTTSHNKGRDSEISSLVTTKEGLLNTPPIEGARDRTPQESQTHSQANLDTLQELEKIMTKKTATHLRYQFEEG…
SIO_010081: YFR019W
subclass of: SO_0000673
so part of: YFR019W
location: 184502..191338
location: region:184502-191338:1
so has part: feature:184502-191338:1:exon

NP_116674.2
type: Protein
SIO_000068: ncbiprotein

S000001915
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:184502-191338:1:exon

YNCF0009C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCF0009C
so part of: sequence
location: complement(191513..191613)
location: region:191513-191613:-1
so has part: feature:191513-191613:-1:exon
subclass of: SO_0000663

850575
type: Gene
SIO_000068: ncbigene

position:191513:-1
position: 191513
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:191613:-1
position: 191613
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:191513-191613:-1:exon

YNCF0009C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCF0009C
product: tRNA-Ser
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Serine tRNA (tRNA-Ser), predicted by tRNAscan-SE analysis
SIO_010081: YNCF0009C
subclass of: SO_0000673
so part of: YNCF0009C
location: complement(join(191513..191557,191577..191613))
location: region:191513-191613:-1
so has part: feature:191577-191613:-1:exon
so has part: feature:191513-191557:-1:exon

S000006731
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:191577-191613:-1:exon

position:191577:-1
position: 191577
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:191513-191557:-1:exon

position:191557:-1
position: 191557
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(191685..191854)
location: region:191685-191854:-1
so has part: feature:191685-191854:-1:region

S000006932
type: SGD
SIO_000068: sgd

position:191685:-1
position: 191685
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:191854:-1
position: 191854
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:191685-191854:-1:region

YFR020W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CSS2
locus tag: YFR020W
so part of: sequence
location: <192737..>193435
location: region:192737-193435:1
so has part: feature:192737-193435:1:exon
subclass of: SO_0000010

850576
type: Gene
SIO_000068: ncbigene

position:192737:1
position: 192737
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:193435:1
position: 193435
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:192737-193435:1:exon

YFR020W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CSS2
locus tag: YFR020W
product: Css2p
transcript id: NM_001270745.1
SIO_010081: YFR020W
subclass of: SO_0000673
so part of: YFR020W
location: <192737..>193435
location: region:192737-193435:1
so has part: feature:192737-193435:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:192737-193435:1:exon

YFR020W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CSS2
locus tag: YFR020W
experiment: EXISTENCE:direct assay:GO:0005576 extracellular region [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
note: hypothetical protein, secreted when constitutively expressed; SWAT-GFP fusion protein localizes to the endoplasmic reticulum (ER) and extracellular region, while mCherry fusion protein localizes to the ER and vacuole; mRNA identified as translated by ribosome profiling data; CSS2 is a non-essential gene
codon start: 1
product: Css2p
translation: MWCYSHFLLIFVSFVTSFAHKLPANNSTTNGGTDGIAVPVIETTIDSGMYSENGTDLMTPEDLPDLLSDGIVLSFANTTETGSDSDSTLIDSEDLRRCIDMPDRSCSAQRGNLCSYSFWDIPFSFLNTVHDIFGMTNMGNCAVMAGDKGAFYYKYYPVEPNCNSTIHQKTIDDALQQATEQLNGDFNNMYFFHVNRGGLWQGDMMVGTRVFTWFAGAKWAEHKGSIEAGFTS
SIO_010081: YFR020W
subclass of: SO_0000673
so part of: YFR020W
location: 192737..193435
location: region:192737-193435:1
so has part: feature:192737-193435:1:exon

NP_001257674.1
type: Protein
SIO_000068: ncbiprotein

S000001916
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:192737-193435:1:exon

YFR021W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: AUT10
alternative label: CVT18
alternative label: NMR1
alternative label: SVP1
gene: ATG18
locus tag: YFR021W
gene synonym: AUT10; CVT18; NMR1; SVP1
so part of: sequence
location: <194812..>196314
location: region:194812-196314:1
so has part: feature:194812-196314:1:exon
subclass of: SO_0000010

850577
type: Gene
SIO_000068: ncbigene

position:194812:1
position: 194812
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:196314:1
position: 196314
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:194812-196314:1:exon

YFR021W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: AUT10
alternative label: CVT18
alternative label: NMR1
alternative label: SVP1
gene: ATG18
locus tag: YFR021W
gene synonym: AUT10; CVT18; NMR1; SVP1
product: phosphoinositide binding protein ATG18
transcript id: NM_001179986.1
SIO_010081: YFR021W
subclass of: SO_0000673
so part of: YFR021W
location: <194812..>196314
location: region:194812-196314:1
so has part: feature:194812-196314:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:194812-196314:1:exon

YFR021W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: AUT10
alternative label: CVT18
alternative label: NMR1
alternative label: SVP1
gene: ATG18
locus tag: YFR021W
gene synonym: AUT10; CVT18; NMR1; SVP1
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:15103325|PMID:22842922|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0000407 phagophore assembly site [PMID:18497569]
experiment: EXISTENCE:direct assay:GO:0005768 endosome [PMID:18769150]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:11707261]
experiment: EXISTENCE:direct assay:GO:0006624 vacuolar protein processing [PMID:11707261]
experiment: EXISTENCE:direct assay:GO:0016236 macroautophagy [PMID:11707261]
experiment: EXISTENCE:direct assay:GO:0032258 cytoplasm to vacuole transport by the Cvt pathway [PMID:11707261]
experiment: EXISTENCE:direct assay:GO:0032266 phosphatidylinositol-3-phosphate binding [PMID:15103325|PMID:15155809]
experiment: EXISTENCE:direct assay:GO:0043130 ubiquitin binding [PMID:21070969]
experiment: EXISTENCE:direct assay:GO:0061908 phagophore [PMID:23549786]
experiment: EXISTENCE:direct assay:GO:0070273 phosphatidylinositol-4-phosphate binding [PMID:15155809]
experiment: EXISTENCE:direct assay:GO:0070772 PAS complex [PMID:19037259]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0080025 phosphatidylinositol-3,5-bisphosphate binding [PMID:15103325]
experiment: EXISTENCE:mutant phenotype:GO:0006624 vacuolar protein processing [PMID:11707261]
experiment: EXISTENCE:mutant phenotype:GO:0016236 macroautophagy [PMID:11707261]
experiment: EXISTENCE:mutant phenotype:GO:0030242 autophagy of peroxisome [PMID:11739783]
experiment: EXISTENCE:mutant phenotype:GO:0032258 cytoplasm to vacuole transport by the Cvt pathway [PMID:11707261|PMID:16876790]
experiment: EXISTENCE:mutant phenotype:GO:0034727 piecemeal microautophagy of the nucleus [PMID:18701704]
experiment: EXISTENCE:mutant phenotype:GO:0044090 positive regulation of vacuole organization [PMID:17699591]
experiment: EXISTENCE:mutant phenotype:GO:0044805 late nucleophagy [PMID:22768199]
experiment: EXISTENCE:mutant phenotype:GO:0045324 late endosome to vacuole transport [PMID:15103325]
experiment: EXISTENCE:physical interaction:GO:0070772 PAS complex [PMID:19037259]
note: Phosphoinositide binding protein; required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (CVT) pathway; binds PtdIns(3,5)P2, PI3P and PI4P; WD-40 repeat containing protein and PROPPIN family member; relocalizes from the vacuole to cytoplasm upon DNA replication stress; mammalian homologs include: WIPI1, WIPI2, WIPI3 and WIPI4/WDR45; mutations in human WDR45 cause static encephalopathy of childhood with neurodegeneration in adulthood (SENDA)
codon start: 1
product: phosphoinositide binding protein ATG18
translation: MSDSSPTINFINFNQTGTCISLGTSKGFKIFNCEPFGKFYSEDSGGYAIVEMLFSTSLLALVGIGDQPALSPRRLRIINTKKHSIICEVTFPTSILSVKMNKSRLVVLLQEQIYIYDINTMRLLHTIETNPNPRGLMAMSPSVANSYLVYPSPPKVINSEIKAHATTNNITLSVGGNTETSFKRDQQDAGHSDISDLDQYSSFTKRDDADPTSSNGGNSSIIKNGDVIVFNLETLQPTMVIEAHKGEIAAMAISFDGTLMATASDKGTIIRVFDIETGDKIYQFRRGTYATRIYSISFSEDSQYLAVTGSSKTVHIFKLGHSMSNNKLDSDDSNMEEAAADDSSLDTTSIDALSDEENPTRLAREPYVDASRKTMGRMIRYSSQKLSRRAARTLGQIFPIKVTSLLESSRHFASLKLPVETNSHVMTISSIGSPIDIDTSEYPELFETGNSASTESYHEPVMKMVPIRVVSSDGYLYNFVMDPERGGDCLILSQYSILMD
SIO_010081: YFR021W
subclass of: SO_0000673
so part of: YFR021W
location: 194812..196314
location: region:194812-196314:1
so has part: feature:194812-196314:1:exon

NP_444297.1
type: Protein
SIO_000068: ncbiprotein

S000001917
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:194812-196314:1:exon

YFR022W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ART7
gene: ROG3
locus tag: YFR022W
gene synonym: ART7
so part of: sequence
location: <196833..>199034
location: region:196833-199034:1
so has part: feature:196833-199034:1:exon
subclass of: SO_0000010

850578
type: Gene
SIO_000068: ncbigene

position:196833:1
position: 196833
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:199034:1
position: 199034
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:196833-199034:1:exon

YFR022W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ART7
gene: ROG3
locus tag: YFR022W
gene synonym: ART7
product: Rog3p
transcript id: NM_001179987.3
SIO_010081: YFR022W
subclass of: SO_0000673
so part of: YFR022W
location: <196833..>199034
location: region:196833-199034:1
so has part: feature:196833-199034:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:196833-199034:1:exon

YFR022W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ART7
gene: ROG3
locus tag: YFR022W
gene synonym: ART7
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0031625 ubiquitin protein ligase binding [PMID:24820415]
experiment: EXISTENCE:genetic interaction:GO:0000754 adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion [PMID:24820415]
experiment: EXISTENCE:genetic interaction:GO:0002092 positive regulation of receptor internalization [PMID:24820415]
experiment: EXISTENCE:mutant phenotype:GO:0000754 adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion [PMID:24820415]
experiment: EXISTENCE:mutant phenotype:GO:0031625 ubiquitin protein ligase binding [PMID:24820415]
experiment: EXISTENCE:physical interaction:GO:0031625 ubiquitin protein ligase binding [PMID:18976803]
note: Alpha-arrestin involved in ubiquitin-dependent endocytosis; contributes to desensitization of agonist-occupied alpha-factor receptor Ste2p by Rsp5p-independent internalization; PPXY motif-mediated binding of the ubiquitin ligase Rsp5p is not required for adaptation; mutation suppresses the temperature sensitivity of an mck1 rim11 double mutant; SWAT-GFP and mCherry fusion proteins localize to the cytosol; ROG3 has a paralog, ROD1, that arose from the whole genome duplication
codon start: 1
product: Rog3p
translation: MGFSSGKSTKKKPLLFDIRLKNVDNDVILLKGPPNEAPSVLLSGCIVLSINEPMQIKSISLRLYGKIQIDVPLERPQDASSSSLSSSPPKIRKYNKVFYNYAWDNVNLKEYLSGLRGQSGLAGSSSSSNILGTRQRAQSTSSLKSLKGSSSPSSCTLDKGNYDFPFSAILPGSLPESVESLPNCFVTYSMESVIERSKNYSDLICRKNIRVLRTISPAAVELSETVCVDNSWPDKVDYSISVPNKAVAIGSATPINISIVPLSKGLKLGSIKVVLFENYQYCDPFPPVISENRQVTELNLEDPLNESSGEFNGNGCFVNNPFFQPDHSFQDKWEIDTILQIPNSLSNCVQDCDVRSNIKVRHKLKFFIILINPDGHKSELRASLPIQLFISPFVALSIKPLSSSNLYSLFSTTNQKDENSSQEEEEEYLFSRSASVTGLELLADMRSGGSVPTISDLMTPPNYEMHVYDRLYSGSFTRTAVETSGTCTPLGSECSTVEDQQQDLEDLRIRLTKIRNQRDNLGLPPSASSAAASRSLSPLLNVPAPEDGTERILPQSALGPNSGSVPGVHSNVSPVLLSRSPAPSVSAHEVLPVPSGLNYPETQNLNKVPSYGKAMKYDIIGEDLPPSYPCAIQNVQPRKPSRVHSRNSSTTLSSSIPTSFHSSSFMSSTASPISIINGSRSSSSGVSLNTLNELTSKTSNNPSSNSMKRSPTRRRATSLAGFMGGFLSKGNKR
SIO_010081: YFR022W
subclass of: SO_0000673
so part of: YFR022W
location: 196833..199034
location: region:196833-199034:1
so has part: feature:196833-199034:1:exon

NP_116677.3
type: Protein
SIO_000068: ncbiprotein

S000001918
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:196833-199034:1:exon

YNCF0010C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RUF22
locus tag: YNCF0010C
so part of: sequence
location: complement(199299..199813)
location: region:199299-199813:-1
so has part: feature:199299-199813:-1:exon
subclass of: SO_0000011

9164891
type: Gene
SIO_000068: ncbigene

position:199299:-1
position: 199299
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:199813:-1
position: 199813
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:199299-199813:-1:exon

YNCF0010C
type: Non Coding RNA
subclass of: SO_0000655
RO_0002162: 559292
nc RNA class: other
gene: RUF22
locus tag: YNCF0010C
product: RUF22
note: RNA of Unknown Function; precise location of 3' end uncertain; RUF22 may be longer than currently annotated
transcript id: NR_132174.1
SIO_010081: YNCF0010C
subclass of: SO_0000673
so part of: YNCF0010C
location: complement(199299..199813)
location: region:199299-199813:-1
so has part: feature:199299-199813:-1:exon

S000130131
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:199299-199813:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS607; Highly-efficient autonomously replicating sequence on Chromosome VI; activated very early in S phase in >85% of cell cycles
so part of: sequence
location: 199395..199505
location: region:199395-199505:1
so has part: feature:199395-199505:1:region

S000007639
type: SGD
SIO_000068: sgd

position:199395:1
position: 199395
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:199505:1
position: 199505
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:199395-199505:1:region

YFR023W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PES4
locus tag: YFR023W
so part of: sequence
location: <199874..>201709
location: region:199874-201709:1
so has part: feature:199874-201709:1:exon
subclass of: SO_0000010

850579
type: Gene
SIO_000068: ncbigene

position:199874:1
position: 199874
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:201709:1
position: 201709
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:199874-201709:1:exon

YFR023W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PES4
locus tag: YFR023W
product: Pes4p
transcript id: NM_001179988.1
SIO_010081: YFR023W
subclass of: SO_0000673
so part of: YFR023W
location: <199874..>201709
location: region:199874-201709:1
so has part: feature:199874-201709:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:199874-201709:1:exon

YFR023W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PES4
locus tag: YFR023W
experiment: EXISTENCE:direct assay:GO:0005628 prospore membrane [PMID:28193845]
experiment: EXISTENCE:genetic interaction:GO:0006417 regulation of translation [PMID:28193845]
experiment: EXISTENCE:genetic interaction:GO:0010609 mRNA localization resulting in post-transcriptional regulation of gene expression [PMID:28193845]
experiment: EXISTENCE:genetic interaction:GO:0016071 mRNA metabolic process [PMID:28193845]
note: Putative RNA binding protein; partially redundant function with paralog MIP6 in the steady-state expression, translational timing and localization of a subset of Ndt80-dependent mRNAs that are protected until translated near the end of meiosis II; regulator of meiotic commitment; redundant function with MIP6 in sporulation; localizes to puncta near the openings of the prospore membrane; suppressor of a DNA polymerase epsilon mutation; induced by NDT80
codon start: 1
product: Pes4p
translation: MYSISNKKPSILSMVPLNILKNQDLKVKKDQEKKISFNPVVTPIRPDDYHEKTSRSSSSSHSDSPEFLRINNNKSGHKNGKLKSFESKKLVPLFIGDLHETVTEETLKGIFKKYPSFVSAKVCLDSVTKKSLGHGYLNFEDKEEAEKAMEELNYTKVNGKEIRIMPSLRNTTFRKNFGTNVFFSNLPLNNPLLTTRVFYDTFSRYGKILSCKLDSRKDIGFVYFEDEKTARNVIKMYNNTSFFGKKILCGIHFDKEVRSVPNFETQKSRLDAETIIEKEQSLNEKHSKGNDKESKNIYSSSQNSIFIKNLPTITTRDDILNFFSEVGPIKSIYLSNATKVKYLWAFVTYKNSSDSEKAIKRYNNFYFRGKKLLVTRAQDKEERAKFIESQKISTLFLENLSAVCNKEFLKYLCHQENIRPFKIQIDGYDENSSTYSGFIKFRNFEDATRIFNFLNNRLVGGSIVTTSWERQNNAPKYHDGYGMRNIHTSSHPQITPYYQYSHANSLNSPHMRDLSSMNSSTRSLIKNKNFNKKVLETFEKQVRRGIDFMRFPSATRDENVHGIAEYIFDTYWNRDVLILDKFLSLLNSSPYHEGVLQKQIEEAASSLGFKR
SIO_010081: YFR023W
subclass of: SO_0000673
so part of: YFR023W
location: 199874..201709
location: region:199874-201709:1
so has part: feature:199874-201709:1:exon

NP_116678.1
type: Protein
SIO_000068: ncbiprotein

S000001919
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:199874-201709:1:exon

YFR024C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YFR024C
gene: LSB3
locus tag: YFR024C-A
gene synonym: YFR024C
so part of: sequence
location: complement(<201960..>203433)
location: region:201960-203433:-1
so has part: feature:201960-203433:-1:exon
subclass of: SO_0000010

850580
type: Gene
SIO_000068: ncbigene

position:201960:-1
position: 201960
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:203433:-1
position: 203433
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:201960-203433:-1:exon

YFR024C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YFR024C
gene: LSB3
locus tag: YFR024C-A
gene synonym: YFR024C
product: Lsb3p
transcript id: NM_001180865.3
SIO_010081: YFR024C-A
subclass of: SO_0000673
so part of: YFR024C-A
location: complement(join(<201960..203292,203387..>203433))
location: region:201960-203433:-1
so has part: feature:203387-203433:-1:exon
so has part: feature:201960-203292:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:203387-203433:-1:exon

position:203387:-1
position: 203387
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:201960-203292:-1:exon

position:203292:-1
position: 203292
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YFR024C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YFR024C
gene: LSB3
locus tag: YFR024C-A
gene synonym: YFR024C
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:14562095]
experiment: EXISTENCE:genetic interaction:GO:0051666 actin cortical patch localization [PMID:19158382]
experiment: EXISTENCE:mutant phenotype:GO:0051666 actin cortical patch localization [PMID:19158382]
note: Protein containing a C-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization; protein abundance increases in response to DNA replication stress; LSB3 has a paralog, YSC84, that arose from the whole genome duplication
codon start: 1
product: Lsb3p
translation: MGINNPIPRSLKSETKKAAKILASFVKPNQVFGADQVIPPDVLKRAKGLAIITILKAGFLFSGRAGSGVIVARLKDGTWSAPSAIAMAGAGAGGMVGIELTDFVFILNTQDAVKSFSEFGTITLGGNVSVSAGPLGRSAEAAASASAGGVAAVFAYSKSKGLFAGVSVEGSAIIERREANRKFYGDNCTAKMILSGRIRPPPAVDPLFRVLESRAFNYRPSNGGRGSFDDDEDDYYDDDDYYNDIPSSFSSTDASSTRPNTRSTRRRAQSGSRYTFDDDDDDDDYGTGYSRNSRLAPTNSGGSGGKLDDPSGASSYYASHRRSGTAQSRARSSRNRWADDEYDDYDDDYESGYRRGNGRDRTKDREVDDLSNRFSKSRISSASTPQTSQGRFTAPTSPSTSSPKAVALYSFAGEESGDLPFRKGDVITILKKSDSQNDWWTGRVNGREGIFPANYVELV
SIO_010081: YFR024C-A
subclass of: SO_0000673
so part of: YFR024C-A
location: complement(join(201960..203292,203387..203433))
location: region:201960-203433:-1
so has part: feature:203387-203433:-1:exon
so has part: feature:201960-203292:-1:exon

NP_219497.4
type: Protein
SIO_000068: ncbiprotein

S000002968
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:203387-203433:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:201960-203292:-1:exon

YFR025C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HIS2
locus tag: YFR025C
so part of: sequence
location: complement(<203743..>204750)
location: region:203743-204750:-1
so has part: feature:203743-204750:-1:exon
subclass of: SO_0000010

850581
type: Gene
SIO_000068: ncbigene

position:203743:-1
position: 203743
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:204750:-1
position: 204750
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:203743-204750:-1:exon

YFR025C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HIS2
locus tag: YFR025C
product: histidinol-phosphatase
transcript id: NM_001179990.1
SIO_010081: YFR025C
subclass of: SO_0000673
so part of: YFR025C
location: complement(<203743..>204750)
location: region:203743-204750:-1
so has part: feature:203743-204750:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:203743-204750:-1:exon

YFR025C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: HIS2
locus tag: YFR025C
EC number: 3.1.3.15
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0000105 histidine biosynthetic process [PMID:14190241]
experiment: EXISTENCE:mutant phenotype:GO:0004401 histidinol-phosphatase activity [PMID:14190241]
note: Histidinolphosphatase; catalyzes the eighth step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control
codon start: 1
product: histidinol-phosphatase
translation: MHSHHSHSGDYSAHGTDPLDSVVDQVVNLNFHTYCLTEHIPRIEAKFIYPEEQSLGKNPEEVITKLETSFKNFMSHAQEIKTRYADRPDVRTKFIIGMEIESCDMAHIEYAKRLMKENNDILKFCVGSVHHVNGIPIDFDQQQWYNSLHSFNDNLKHFLLSYFQSQYEMLINIKPLVVGHFDLYKLFLPNDMLVNQKSGNCNEETGVPVASLDVISEWPEIYDAVVRNLQFIDSYGGAIEINTSALRKRLEEPYPSKTLCNLVKKHCGSRFVLSDDAHGVAQVGVCYDKVKKYIVDVLQLEYICYLEESQSPENLLTVKRLPISQFVNDPFWANI
SIO_010081: YFR025C
subclass of: SO_0000673
so part of: YFR025C
location: complement(203743..204750)
location: region:203743-204750:-1
so has part: feature:203743-204750:-1:exon

NP_116681.1
type: Protein
SIO_000068: ncbiprotein

S000001921
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:203743-204750:-1:exon

YNCF0011C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCF0011C
so part of: sequence
location: complement(204924..204996)
location: region:204924-204996:-1
so has part: feature:204924-204996:-1:exon
subclass of: SO_0000663

850582
type: Gene
SIO_000068: ncbigene

position:204924:-1
position: 204924
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:204996:-1
position: 204996
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:204924-204996:-1:exon

YNCF0011C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCF0011C
product: tRNA-Ala
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Alanine tRNA (tRNA-Ala), predicted by tRNAscan-SE analysis; one of 11 nuclear tRNA genes containing the tDNA-anticodon AGC (converted to IGC in the mature tRNA), decodes GCU and GCC codons into alanine, one of 16 nuclear tRNAs for alanine
SIO_010081: YNCF0011C
subclass of: SO_0000673
so part of: YNCF0011C
location: complement(204924..204996)
location: region:204924-204996:-1
so has part: feature:204924-204996:-1:exon

S000006511
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:204924-204996:-1:exon

YFR026C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ULI1
locus tag: YFR026C
so part of: sequence
location: complement(<205748..>206257)
location: region:205748-206257:-1
so has part: feature:205748-206257:-1:exon
subclass of: SO_0000010

850583
type: Gene
SIO_000068: ncbigene

position:205748:-1
position: 205748
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:206257:-1
position: 206257
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:205748-206257:-1:exon

YFR026C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ULI1
locus tag: YFR026C
product: Uli1p
transcript id: NM_001179991.3
SIO_010081: YFR026C
subclass of: SO_0000673
so part of: YFR026C
location: complement(<205748..>206257)
location: region:205748-206257:-1
so has part: feature:205748-206257:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:205748-206257:-1:exon

YFR026C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ULI1
locus tag: YFR026C
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0030968 endoplasmic reticulum unfolded protein response [PMID:19073890]
note: hypothetical protein; involved in and induced by the endoplasmic reticulum unfolded protein response (UPR); SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum
codon start: 1
product: Uli1p
translation: MTPYAVAITVALLIVTVSALQVNNSCVAFPPSNLRGKNGDGTNEQYATALLSIPWNGPPESLRDINLIELEPQVALYLLENYINHYYNTTRDNKCPNNHYLMGGQLGSSSDNRSLNDPQTMLWPEKKEDEKNCQETFKGACSCTKRFCKGYFSVNIFGINLNISYSSGK
SIO_010081: YFR026C
subclass of: SO_0000673
so part of: YFR026C
location: complement(205748..206257)
location: region:205748-206257:-1
so has part: feature:205748-206257:-1:exon

NP_116682.3
type: Protein
SIO_000068: ncbiprotein

S000001922
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:205748-206257:-1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 206922..207138
location: region:206922-207138:1
so has part: feature:206922-207138:1:region

S000006934
type: SGD
SIO_000068: sgd

position:206922:1
position: 206922
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:207138:1
position: 207138
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:206922-207138:1:region

YFR027W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CTF7
gene: ECO1
locus tag: YFR027W
gene synonym: CTF7
so part of: sequence
location: <207452..>208297
location: region:207452-208297:1
so has part: feature:207452-208297:1:exon
subclass of: SO_0000010

850584
type: Gene
SIO_000068: ncbigene

position:207452:1
position: 207452
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:208297:1
position: 208297
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:207452-208297:1:exon

YFR027W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CTF7
gene: ECO1
locus tag: YFR027W
gene synonym: CTF7
product: Eco1p
transcript id: NM_001179992.1
SIO_010081: YFR027W
subclass of: SO_0000673
so part of: YFR027W
location: <207452..>208297
location: region:207452-208297:1
so has part: feature:207452-208297:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:207452-208297:1:exon

YFR027W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CTF7
gene: ECO1
locus tag: YFR027W
gene synonym: CTF7
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0006281 DNA repair [PMID:11448778]
experiment: EXISTENCE:direct assay:GO:0016407 acetyltransferase activity [PMID:11864574|PMID:18614053|PMID:22593213]
experiment: EXISTENCE:direct assay:GO:0018393 internal peptidyl-lysine acetylation [PMID:18614053]
experiment: EXISTENCE:direct assay:GO:0043596 nuclear replication fork [PMID:16962805]
experiment: EXISTENCE:genetic interaction:GO:0034087 establishment of mitotic sister chromatid cohesion [PMID:16934511]
experiment: EXISTENCE:mutant phenotype:GO:0006260 DNA replication [PMID:9990856]
experiment: EXISTENCE:mutant phenotype:GO:0006302 double-strand break repair [PMID:11448778]
experiment: EXISTENCE:mutant phenotype:GO:0006979 response to oxidative stress [PMID:34897432]
experiment: EXISTENCE:mutant phenotype:GO:0007076 mitotic chromosome condensation [PMID:19948494]
experiment: EXISTENCE:mutant phenotype:GO:0016407 acetyltransferase activity [PMID:22593213]
experiment: EXISTENCE:mutant phenotype:GO:0032200 telomere organization [PMID:19948494]
experiment: EXISTENCE:mutant phenotype:GO:0034087 establishment of mitotic sister chromatid cohesion [PMID:9990855|PMID:9990856]
experiment: EXISTENCE:mutant phenotype:GO:0034089 establishment of meiotic sister chromatid cohesion [PMID:35103590]
experiment: EXISTENCE:mutant phenotype:GO:0051276 chromosome organization [PMID:19948494]
experiment: EXISTENCE:mutant phenotype:GO:0070058 tRNA gene clustering [PMID:19948494]
experiment: EXISTENCE:mutant phenotype:GO:0140588 chromatin looping [PMID:32032532]
note: Acetyltransferase required for sister chromatid cohesion; elicits cohesin dimerization during S phase; acetylates Mps3p to regulate nuclear organization; modifies Smc3p at replication forks and Mcd1p in response to dsDNA breaks; phosphorylated by Cdc28p, Cdc7p, Mck1p to generate pair of phosphates spaced precisely for recognition by ubiquitin ligase SCF-Cdc4; relative distribution to nucleus increases upon DNA replication stress; mutations in human homolog ESCO2 cause Roberts syndrome
codon start: 1
product: Eco1p
translation: MKARKSQRKAGSKPNLIQSKLQVNNGSKSNKIVKCDKCEMSYSSTSIEDRAIHEKYHTLQLHGRKWSPNWGSIVYTERNHSRTVHLSRSTGTITPLNSSPLKKSSPSITHQEEKIVYVRPDKSNGEVRAMTEIMTLVNNELNAPHDENVIWNSTTEEKGKAFVYIRNDRAVGIIIIENLYGGNGKTSSRGRWMVYDSRRLVQNVYPDFKIGISRIWVCRTARKLGIATKLIDVARENIVYGEVIPRYQVAWSQPTDSGGKLASKYNGIMHKSGKLLLPVYI
SIO_010081: YFR027W
subclass of: SO_0000673
so part of: YFR027W
location: 207452..208297
location: region:207452-208297:1
so has part: feature:207452-208297:1:exon

NP_116683.1
type: Protein
SIO_000068: ncbiprotein

S000001923
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:207452-208297:1:exon

YFR028C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: OAF3
gene: CDC14
locus tag: YFR028C
gene synonym: OAF3
so part of: sequence
location: complement(<208413..>210068)
location: region:208413-210068:-1
so has part: feature:208413-210068:-1:exon
subclass of: SO_0000010

850585
type: Gene
SIO_000068: ncbigene

position:208413:-1
position: 208413
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:210068:-1
position: 210068
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:208413-210068:-1:exon

YFR028C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: OAF3
gene: CDC14
locus tag: YFR028C
gene synonym: OAF3
product: phosphoprotein phosphatase CDC14
transcript id: NM_001179993.3
SIO_010081: YFR028C
subclass of: SO_0000673
so part of: YFR028C
location: complement(<208413..>210068)
location: region:208413-210068:-1
so has part: feature:208413-210068:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:208413-210068:-1:exon

YFR028C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: OAF3
gene: CDC14
locus tag: YFR028C
gene synonym: OAF3
EC number: 3.1.3.48
experiment: EXISTENCE:direct assay:GO:0004721 phosphoprotein phosphatase activity [PMID:9295359|PMID:17173039|PMID:24319056|PMID:24954044]
experiment: EXISTENCE:direct assay:GO:0004722 protein serine/threonine phosphatase activity [PMID:26085509|PMID:35238874]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:26090959|PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:12062061|PMID:26090959|PMID:36259662]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:26090959]
experiment: EXISTENCE:direct assay:GO:0005816 spindle pole body [PMID:12062061]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:36259662]
experiment: EXISTENCE:direct assay:GO:0010508 positive regulation of autophagy [PMID:35238874]
experiment: EXISTENCE:direct assay:GO:0030869 RENT complex [PMID:10219244]
experiment: EXISTENCE:direct assay:GO:0044732 mitotic spindle pole body [PMID:36259662]
experiment: EXISTENCE:direct assay:GO:0071958 new mitotic spindle pole body [PMID:36259662]
experiment: EXISTENCE:direct assay:GO:0140013 meiotic nuclear division [PMID:35238874]
experiment: EXISTENCE:genetic interaction:GO:1903501 positive regulation of mitotic actomyosin contractile ring assembly [PMID:26085509]
experiment: EXISTENCE:mutant phenotype:GO:0000278 mitotic cell cycle [PMID:6749599]
experiment: EXISTENCE:mutant phenotype:GO:0000422 autophagy of mitochondrion [PMID:29694832]
experiment: EXISTENCE:mutant phenotype:GO:0007059 chromosome segregation [PMID:16769819]
experiment: EXISTENCE:mutant phenotype:GO:0007096 regulation of exit from mitosis [PMID:10219244]
experiment: EXISTENCE:mutant phenotype:GO:0016479 negative regulation of transcription by RNA polymerase I [PMID:19158678]
experiment: EXISTENCE:mutant phenotype:GO:0032467 positive regulation of cytokinesis [PMID:25371407]
experiment: EXISTENCE:mutant phenotype:GO:0051229 meiotic spindle disassembly [PMID:12737806]
experiment: EXISTENCE:mutant phenotype:GO:0071470 cellular response to osmotic stress [PMID:25411400]
experiment: EXISTENCE:mutant phenotype:GO:1903501 positive regulation of mitotic actomyosin contractile ring assembly [PMID:26085509]
experiment: EXISTENCE:mutant phenotype:GO:2000786 positive regulation of autophagosome assembly [PMID:29694832]
note: Protein phosphatase required for mitotic exit; required for rDNA segregation, cytokinesis, meiosis I spindle disassembly, environmental stress response, autophagy during meiosis; downregulates microautophagy induction after TORC1
codon start: 1
product: phosphoprotein phosphatase CDC14
translation: MRRSVYLDNTIEFLRGRVYLGAYDYTPEDTDELVFFTVEDAIFYNSFHLDFGPMNIGHLYRFAVIFHEILNDPENANKAVVFYSSASTRQRANAACMLCCYMILVQAWTPHQVLQPLAQVDPPFMPFRDAGYSNADFEITIQDVVYGVWRAKEKGLIDLHSFNLESYEKYEHVEFGDFNVLTPDFIAFASPQEDHPKGYLATKSSHLNQPFKSVLNFFANNNVQLVVRLNSHLYNKKHFEDIGIQHLDLIFEDGTCPDLSIVKNFVGAAETIIKRGGKIAVHCKAGLGRTGCLIGAHLIYTYGFTANECIGFLRFIRPGMVVGPQQHWLYLHQNDFREWKYTTRISLKPSEAIGGLYPLISLEEYRLQKKKLKDDKRVAQNNIEGELRDLTMTPPSNGHGALSARNSSQPSTANNGSNSFKSSAVPQTSPGQPRKGQNGSNTIEDINNNRNPTSHANRKVVIESNNSDDESMQDTNGTSNHYPKVSRKKNDISSASSSRMEDNEPSATNINNAADDTILRQLLPKNRRVTSGRRTTSAAGGIRKISGSIKK
SIO_010081: YFR028C
subclass of: SO_0000673
so part of: YFR028C
location: complement(208413..210068)
location: region:208413-210068:-1
so has part: feature:208413-210068:-1:exon

NP_116684.3
type: Protein
SIO_000068: ncbiprotein

S000001924
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:208413-210068:-1:exon

YNCF0012C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SUP6
locus tag: YNCF0012C
so part of: sequence
location: complement(210619..210707)
location: region:210619-210707:-1
so has part: feature:210619-210707:-1:exon
subclass of: SO_0000663

850586
type: Gene
SIO_000068: ncbigene

position:210619:-1
position: 210619
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:210707:-1
position: 210707
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:210619-210707:-1:exon

YNCF0012C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
gene: SUP6
locus tag: YNCF0012C
product: tRNA-Tyr
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Tyrosine tRNA (tRNA-Tyr), predicted by tRNAscan-SE analysis; can mutate to suppress ochre nonsense mutations
SIO_010081: YNCF0012C
subclass of: SO_0000673
so part of: YNCF0012C
location: complement(join(210619..210654,210669..210707))
location: region:210619-210707:-1
so has part: feature:210669-210707:-1:exon
so has part: feature:210619-210654:-1:exon

S000006780
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:210669-210707:-1:exon

position:210669:-1
position: 210669
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:210619-210654:-1:exon

position:210654:-1
position: 210654
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YFR029W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RAA2
alternative label: SSY3
gene: PTR3
locus tag: YFR029W
gene synonym: RAA2; SSY3
so part of: sequence
location: <210937..>212973
location: region:210937-212973:1
so has part: feature:210937-212973:1:exon
subclass of: SO_0000010

850587
type: Gene
SIO_000068: ncbigene

position:210937:1
position: 210937
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:212973:1
position: 212973
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:210937-212973:1:exon

YFR029W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RAA2
alternative label: SSY3
gene: PTR3
locus tag: YFR029W
gene synonym: RAA2; SSY3
product: Ptr3p
transcript id: NM_001179994.1
SIO_010081: YFR029W
subclass of: SO_0000673
so part of: YFR029W
location: <210937..>212973
location: region:210937-212973:1
so has part: feature:210937-212973:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:210937-212973:1:exon

YFR029W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RAA2
alternative label: SSY3
gene: PTR3
locus tag: YFR029W
gene synonym: RAA2; SSY3
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:10409731]
experiment: EXISTENCE:mutant phenotype:GO:0043200 response to amino acid [PMID:10409731]
note: Component of the SPS plasma membrane amino acid sensor system; senses external amino acid concentration and transmits intracellular signals that result in regulation of expression of amino acid permease genes; other members are Ssy1p, Ptr3p, and Ssy5p
codon start: 1
product: Ptr3p
translation: MHSHRQKWGRQTDIARVLDDIEHDLYLPQRLSLDGATGTDESHVQYGIVKDCSVLTCGCCISESLFNDLCRETSNKQTACPICQRENVRLLSAIKPLRDLARQIDFFRSTTGQGESESDELPAIVKTSPSSSSLSLTPSRSSSTAGLEADNKTLSDPTVKEKSSLLELFHIVASKMHNANTEVGSDHPLTTGTTRDQEEHTTKENYSSSLLEPNYDDHANWKILDNASNTRTVPIDNNFSLMSTDVTIPSTANYQTNSAHDLDEEKEYFFANCFPMYRKKFQFNTHPKFLGTKSKLFINQSISPDCTKFALITEHKWEIYSINPKDNSPQLVSCGKSSGEYGPNFNQLTEQSSSSLSTTSQASKKKKKNWSQRFCKLSNDFLIISGSQNILNVHDIHQNGKLIYTYVSRFPIRCIDIDPRSQIIAYGITGKDRHTGAEQALVVIQQITRNKVTLEPEFPPPITITLPYRDPINTIQLSHDAKYLTCSTALESRFLIISLQKINEPRLIMKSVRSIDTSLESEGITDTKLFPGNPNLMCITSTAFNSSPLVINTKITQINGVRTVAQPSMLIRVDEIGCKIHKCEISPRNDAIAFLDRNGSVYIMCAPTMMDNNEKRRTILVETVANAYRAYESATLRFNPEGNKLYILDRKGTFFVEDFAYGLPQSREITKCKQIFHK
SIO_010081: YFR029W
subclass of: SO_0000673
so part of: YFR029W
location: 210937..212973
location: region:210937-212973:1
so has part: feature:210937-212973:1:exon

NP_116685.1
type: Protein
SIO_000068: ncbiprotein

S000001925
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:210937-212973:1:exon

YFR030W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MET10
locus tag: YFR030W
so part of: sequence
location: <213312..>216419
location: region:213312-216419:1
so has part: feature:213312-216419:1:exon
subclass of: SO_0000010

850588
type: Gene
SIO_000068: ncbigene

position:213312:1
position: 213312
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:216419:1
position: 216419
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:213312-216419:1:exon

YFR030W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MET10
locus tag: YFR030W
product: sulfite reductase subunit alpha
transcript id: NM_001179995.3
SIO_010081: YFR030W
subclass of: SO_0000673
so part of: YFR030W
location: <213312..>216419
location: region:213312-216419:1
so has part: feature:213312-216419:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:213312-216419:1:exon

YFR030W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MET10
locus tag: YFR030W
EC number: 1.8.1.2
experiment: EXISTENCE:direct assay:GO:0004783 sulfite reductase (NADPH) activity [PMID:6751400]
experiment: EXISTENCE:direct assay:GO:0009337 sulfite reductase complex (NADPH) [PMID:6751400]
experiment: EXISTENCE:mutant phenotype:GO:0000103 sulfate assimilation [PMID:19236486|PMID:7928966]
note: Subunit alpha of assimilatory sulfite reductase; complex converts sulfite into sulfide
codon start: 1
product: sulfite reductase subunit alpha
translation: MPVEFATNPFGEAKNATSLPKYGTPVTAISSVLFNNVDSIFAYKSFSQPDLLHQDLKKWSEKRGNESRGKPFFQELDIRSGAGLAPLGFSHGLKNTTAIVAPGFSLPYFINSLKTVSHDGKFLLNVGALNYDNATGSVTNDYVTALDAASKLKYGVVTPISANEVQSVALLALAIATFSNNSGAINLFDGLNYSKTVLPLVESVPEASILAKLSKVIAPDAAFDDVLDKFNELTGLRLHNFQYFGAQDAETVFITYGSLESELFNSAISGNNSKIGLINVRVPLPFNVAKFVTHVPSTTKQIVVIGQTLDGSSPSFLRSQVSAALFYHGRTSISVSEYIYQPDFIWSPKAVKSIVSSFIPEFTYNADSSFGEGFIYWASDKSINIDVASKLVKALSLEDGKFVSLRTKFDNLANAGTFQAQFVTSKEQIPVSNIDSTKLSVVEDVSLLKHLDVAATVAEQGSIALVSQKAVKDLDLNSVESYVKNLGIPESFLISIAKKNIKLFIIDGETTNDESKLSLFIQAVFWKLAFGLDVAECTNRIWKSIDSGADISAASISEFLTGAFKNFLSEVPLALYTKFSEINIEKKEDEEEPAALPIFVNETSFLPNNSTIEEIPLPETSEISDIAKKLSFKEAYEVENKLRPDLPVKNFVVKVKENRRVTPADYDRYIFHIEFDISGTGMTYDIGEALGIHARNNESLVKEFLTFYGLNESDVVLVPNKDNHHLLETRTVLQAFVENLDIFGKPPKRFYESLIPYASNEEEKKKLEDLVTPAGAVDLKRFQDVEYYTYADIFELFPSVRPSLEELVTIIEPLKRREYSIASSQKVHPNEVHLLIVVVDWVDNKGRKRYGQASKYISDLAVGSELVVSVKPSVMKLPPSPKQPVIMSGLGTGLAPFKAIVEEKLWQKQQGYEIGEVFLYLGSRHKREEYLYGELWEAYKDAGIITHIGAAFSRDQPQKIYIQDRIKENLDELKTAMIDNKGSFYLCGPTWPVPDITQALQDILAKDAEERGIKVDLDAAIEELKEASRYILEVY
SIO_010081: YFR030W
subclass of: SO_0000673
so part of: YFR030W
location: 213312..216419
location: region:213312-216419:1
so has part: feature:213312-216419:1:exon

NP_116686.3
type: Protein
SIO_000068: ncbiprotein

S000001926
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:213312-216419:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS608; Extremely inefficient autonomously replicating sequence on Chr VI; activated early in S phase in <10% of cell cycles
so part of: sequence
location: 216357..216704
location: region:216357-216704:1
so has part: feature:216357-216704:1:region

S000007640
type: SGD
SIO_000068: sgd

position:216357:1
position: 216357
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:216704:1
position: 216704
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:216357-216704:1:region

YFR031C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SMC2
locus tag: YFR031C
so part of: sequence
location: complement(<216594..>220106)
location: region:216594-220106:-1
so has part: feature:216594-220106:-1:exon
subclass of: SO_0000010

850589
type: Gene
SIO_000068: ncbigene

position:216594:-1
position: 216594
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:220106:-1
position: 220106
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:216594-220106:-1:exon

YFR031C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SMC2
locus tag: YFR031C
product: condensin subunit SMC2
transcript id: NM_001179996.2
SIO_010081: YFR031C
subclass of: SO_0000673
so part of: YFR031C
location: complement(<216594..>220106)
location: region:216594-220106:-1
so has part: feature:216594-220106:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:216594-220106:-1:exon

YFR031C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SMC2
locus tag: YFR031C
experiment: EXISTENCE:curator inference:GO:0007130 synaptonemal complex assembly [PMID:10811823]
experiment: EXISTENCE:curator inference:GO:0010032 meiotic chromosome condensation [PMID:10811823]
experiment: EXISTENCE:curator inference:GO:0051307 meiotic chromosome separation [PMID:10811823]
experiment: EXISTENCE:direct assay:GO:0000217 DNA secondary structure binding [PMID:9727028]
experiment: EXISTENCE:direct assay:GO:0000796 condensin complex [PMID:10811823]
experiment: EXISTENCE:direct assay:GO:0003680 minor groove of adenine-thymine-rich DNA binding [PMID:9727028]
experiment: EXISTENCE:direct assay:GO:0003682 chromatin binding [PMID:16055730]
experiment: EXISTENCE:direct assay:GO:0003690 double-stranded DNA binding [PMID:9727028]
experiment: EXISTENCE:direct assay:GO:0005524 ATP binding [PMID:9727028]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0016887 ATP hydrolysis activity [PMID:12719426]
experiment: EXISTENCE:mutant phenotype:GO:0000070 mitotic sister chromatid segregation [PMID:10811823]
experiment: EXISTENCE:mutant phenotype:GO:0007076 mitotic chromosome condensation [PMID:10811823]
experiment: EXISTENCE:mutant phenotype:GO:0070058 tRNA gene clustering [PMID:18708579]
experiment: EXISTENCE:mutant phenotype:GO:0070550 rDNA chromatin condensation [PMID:10811823]
experiment: EXISTENCE:mutant phenotype:GO:1903342 negative regulation of meiotic DNA double-strand break formation [PMID:25103240]
note: Subunit of the condensin complex; condensin reorganizes chromosomes during both mitosis and meiosis; essential SMC chromosomal ATPase family member that forms a subcomplex with Smc2p that has ATP-hydrolyzing and DNA-binding activity, but other condensin subunits are required for chromatin binding; required for clustering of tRNA genes at the nucleolus
codon start: 1
product: condensin subunit SMC2
translation: MKVEELIIDGFKSYATRTVITDWDPQFNAITGLNGSGKSNILDAICFVLGIASMSTVRASSLQDLIYKRGQAGVTKASVTIVFDNTDKSNSPIGFTNSPQISVTRQVVLGGTSKYLINGHRAPQQSVLQLFQSVQLNINNPNFLIMQGKITKVLNMKPSEILSLIEEAAGTKMFEDRREKAERTMSKKETKLQENRTLLTEEIEPKLEKLRNEKRMFLEFQSTQTDLEKTERIVVSYEYYNIKHKHTSIRETLENGETRMKMLNEFVKKTSEEIDSLNEDVEEIKLQKEKELHKEGTISKLENKENGLLNEISRLKTSLSIKVENLNDTTEKSKALESEIASSSAKLIEKKSAYANTEKDYKMVQEQLSKQRDLYKRKEELVSTLTTGISSTGAADGGYNAQLAKAKTELNEVSLAIKKSSMKMELLKKELLTIEPKLKEATKDNELNVKHVKQCQETCDKLRARLVEYGFDPSRIKDLKQREDKLKSHYYQTCKNSEYLKRRVTNLEFNYTKPYPNFEASFVHGVVGQLFQIDNDNIRYATALQTCAGGRLFNVVVQDSQTATQLLERGRLRKRVTIIPLDKIYTRPISSQVLDLAKKIAPGKVELAINLIRFDESITKAMEFIFGNSLICEDPETAKKITFHPKIRARSITLQGDVYDPEGTLSGGSRNTSESLLVDIQKYNQIQKQIETIQADLNHVTEELQTQYATSQKTKTIQSDLNLSLHKLDLAKRNLDANPSSQIIARNEEILRDIGECENEIKTKQMSLKKCQEEVSTIEKDMKEYDSDKGSKLNELKKELKLLAKELEEQESESERKYDLFQNLELETEQLSSELDSNKTLLHNHLKSIESLKLENSDLEGKIRGVEDDLVTVQTELNEEKKRLMDIDDELNELETLIKKKQDEKKSSELELQKLVHDLNKYKSNTNNMEKIIEDLRQKHEFLEDFDLVRNIVKQNEGIDLDTYRERSKQLNEKFQELRKKVNPNIMNMIENVEKKEAALKTMIKTIEKDKMKIQETISKLNEYKRETLVKTWEKVTLDFGNIFADLLPNSFAKLVPCEGKDVTQGLEVKVKLGNIWKESLIELSGGQRSLIALSLIMALLQFRPAPMYILDEVDAALDLSHTQNIGHLIKTRFKGSQFIVVSLKEGMFANANRVFRTRFQDGTSVVSIM
SIO_010081: YFR031C
subclass of: SO_0000673
so part of: YFR031C
location: complement(216594..220106)
location: region:216594-220106:-1
so has part: feature:216594-220106:-1:exon

NP_116687.1
type: Protein
SIO_000068: ncbiprotein

S000001927
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:216594-220106:-1:exon

YFR031C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RPL5B
gene: RPL2A
locus tag: YFR031C-A
gene synonym: RPL5B
so part of: sequence
location: complement(<220507..>221418)
location: region:220507-221418:-1
so has part: feature:220507-221418:-1:exon
subclass of: SO_0000010

850590
type: Gene
SIO_000068: ncbigene

position:220507:-1
position: 220507
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:221418:-1
position: 221418
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:220507-221418:-1:exon

YFR031C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RPL5B
gene: RPL2A
locus tag: YFR031C-A
gene synonym: RPL5B
product: ribosomal 60S subunit protein L2A
transcript id: NM_001180030.3
SIO_010081: YFR031C-A
subclass of: SO_0000673
so part of: YFR031C-A
location: complement(join(<220507..221267,221415..>221418))
location: region:220507-221418:-1
so has part: feature:221415-221418:-1:exon
so has part: feature:220507-221267:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:221415-221418:-1:exon

position:221415:-1
position: 221415
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:220507-221267:-1:exon

position:221267:-1
position: 221267
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YFR031C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RPL5B
gene: RPL2A
locus tag: YFR031C-A
gene synonym: RPL5B
experiment: EXISTENCE:direct assay:GO:0002181 cytoplasmic translation [PMID:18782943]
experiment: EXISTENCE:direct assay:GO:0003735 structural constituent of ribosome [PMID:18782943]
experiment: EXISTENCE:direct assay:GO:0022625 cytosolic large ribosomal subunit [PMID:18782943]
experiment: EXISTENCE:mutant phenotype:GO:0042273 ribosomal large subunit biogenesis [PMID:18263608]
experiment: EXISTENCE:mutant phenotype:GO:1990145 maintenance of translational fidelity [PMID:18263608]
note: Ribosomal 60S subunit protein L2A; homologous to mammalian ribosomal protein L2 and bacterial L2; RPL2A has a paralog, RPL2B, that arose from the whole genome duplication
codon start: 1
product: ribosomal 60S subunit protein L2A
translation: MGRVIRNQRKGAGSIFTSHTRLRQGAAKLRTLDYAERHGYIRGIVKQIVHDSGRGAPLAKVVFRDPYKYRLREEIFIANEGVHTGQFIYAGKKASLNVGNVLPLGSVPEGTIVSNVEEKPGDRGALARASGNYVIIIGHNPDENKTRVRLPSGAKKVISSDARGVIGVIAGGGRVDKPLLKAGRAFHKYRLKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRGAVSGQKAGLIAARRTGLLRGSQKTQD
SIO_010081: YFR031C-A
subclass of: SO_0000673
so part of: YFR031C-A
location: complement(join(220507..221267,221415..221418))
location: region:220507-221418:-1
so has part: feature:221415-221418:-1:exon
so has part: feature:220507-221267:-1:exon

NP_116688.3
type: Protein
SIO_000068: ncbiprotein

S000002104
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:221415-221418:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:220507-221267:-1:exon

YNCF0013W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RUF23
locus tag: YNCF0013W
so part of: sequence
location: 221714..221967
location: region:221714-221967:1
so has part: feature:221714-221967:1:exon
subclass of: SO_0000011

9164890
type: Gene
SIO_000068: ncbigene

position:221714:1
position: 221714
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:221967:1
position: 221967
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:221714-221967:1:exon

YNCF0013W
type: Non Coding RNA
subclass of: SO_0000655
RO_0002162: 559292
nc RNA class: other
gene: RUF23
locus tag: YNCF0013W
product: RUF23
note: RNA of Unknown Function; precise location of 3' end uncertain; RUF23 may be longer than currently annotated
transcript id: NR_132175.1
SIO_010081: YNCF0013W
subclass of: SO_0000673
so part of: YNCF0013W
location: 221714..221967
location: region:221714-221967:1
so has part: feature:221714-221967:1:exon

S000130133
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:221714-221967:1:exon

YFR032C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RRT5
locus tag: YFR032C
so part of: sequence
location: complement(<222090..>222959)
location: region:222090-222959:-1
so has part: feature:222090-222959:-1:exon
subclass of: SO_0000010

850591
type: Gene
SIO_000068: ncbigene

position:222090:-1
position: 222090
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:222959:-1
position: 222959
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:222090-222959:-1:exon

YFR032C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RRT5
locus tag: YFR032C
product: Rrt5p
transcript id: NM_001179997.1
SIO_010081: YFR032C
subclass of: SO_0000673
so part of: YFR032C
location: complement(<222090..>222959)
location: region:222090-222959:-1
so has part: feature:222090-222959:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:222090-222959:-1:exon

YFR032C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RRT5
locus tag: YFR032C
experiment: EXISTENCE:direct assay:GO:0005628 prospore membrane [PMID:24390141]
note: hypothetical protein; non-essential gene identified in a screen for mutants with increased levels of rDNA transcription; expressed at high levels during sporulation
codon start: 1
product: Rrt5p
translation: MTEQVNNDTTSDTTTTITTVYISNLPFTASERDLHAFLNNYGASSVLIPTQTVRRFSKRHNSNPRKPLGIAFAQFANNTLALKAIQDLNGTVFQNQKLFLKLHVPYEADSTPDTDVKKPKEKNKVKKTPETAADTVYCHDLPDDITDSEIRELFQLYSPQEIWIYRSKVYRRKCIPFAPHQITAALVTLQSETPIGDICDSVAKTATLRGKSIIVKPAYVSKIQEIKQLVKDNLTNARDPPPAALAEPAPAPAPVEPAEQVQEGQDNAETNDVPPPPASSSDRPTVAAT
SIO_010081: YFR032C
subclass of: SO_0000673
so part of: YFR032C
location: complement(222090..222959)
location: region:222090-222959:-1
so has part: feature:222090-222959:-1:exon

NP_116689.1
type: Protein
SIO_000068: ncbiprotein

S000001928
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:222090-222959:-1:exon

YFR032C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RPL29
locus tag: YFR032C-A
so part of: sequence
location: complement(<223258..>223437)
location: region:223258-223437:-1
so has part: feature:223258-223437:-1:exon
subclass of: SO_0000010

850592
type: Gene
SIO_000068: ncbigene

position:223258:-1
position: 223258
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:223437:-1
position: 223437
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:223258-223437:-1:exon

YFR032C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RPL29
locus tag: YFR032C-A
product: ribosomal 60S subunit protein L29
transcript id: NM_001184311.3
SIO_010081: YFR032C-A
subclass of: SO_0000673
so part of: YFR032C-A
location: complement(<223258..>223437)
location: region:223258-223437:-1
so has part: feature:223258-223437:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:223258-223437:-1:exon

YFR032C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RPL29
locus tag: YFR032C-A
experiment: EXISTENCE:direct assay:GO:0002181 cytoplasmic translation [PMID:18782943]
experiment: EXISTENCE:direct assay:GO:0003735 structural constituent of ribosome [PMID:18782943]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0022625 cytosolic large ribosomal subunit [PMID:18782943]
note: Ribosomal 60S subunit protein L29; not essential for translation, but required for proper joining of large and small ribosomal subunits and for normal translation rate; homologous to mammalian ribosomal protein L29, no bacterial homolog
codon start: 1
product: ribosomal 60S subunit protein L29
translation: MAKSKNHTAHNQTRKAHRNGIKKPKTYKYPSLKGVDPKFRRNHKHALHGTAKALAAAKK
SIO_010081: YFR032C-A
subclass of: SO_0000673
so part of: YFR032C-A
location: complement(223258..223437)
location: region:223258-223437:-1
so has part: feature:223258-223437:-1:exon

NP_116690.3
type: Protein
SIO_000068: ncbiprotein

S000006437
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:223258-223437:-1:exon

YFR032C-B
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MIN10
locus tag: YFR032C-B
so part of: sequence
location: complement(<223710..>223973)
location: region:223710-223973:-1
so has part: feature:223710-223973:-1:exon
subclass of: SO_0000010

1466402
type: Gene
SIO_000068: ncbigene

position:223710:-1
position: 223710
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:223973:-1
position: 223973
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:223710-223973:-1:exon

YFR032C-B
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MIN10
locus tag: YFR032C-B
product: Min10p
transcript id: NM_001184591.1
SIO_010081: YFR032C-B
subclass of: SO_0000673
so part of: YFR032C-B
location: complement(<223710..>223973)
location: region:223710-223973:-1
so has part: feature:223710-223973:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:223710-223973:-1:exon

YFR032C-B
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MIN10
locus tag: YFR032C-B
note: Mitochondrial hypothetical protein; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
codon start: 1
product: Min10p
translation: MVASRARENQRYSQCRKSTIFPLGFAIISGYIQFQNISILHISRFNPLFYNIFHSIFKNPGTTIQLESTLYYHEVPISPIGNAGSQI
SIO_010081: YFR032C-B
subclass of: SO_0000673
so part of: YFR032C-B
location: complement(223710..223973)
location: region:223710-223973:-1
so has part: feature:223710-223973:-1:exon

NP_878072.1
type: Protein
SIO_000068: ncbiprotein

S000028630
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:223710-223973:-1:exon

YFR033C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: COR3
alternative label: UCR6
gene: QCR6
locus tag: YFR033C
gene synonym: COR3; UCR6
so part of: sequence
location: complement(<224326..>224769)
location: region:224326-224769:-1
so has part: feature:224326-224769:-1:exon
subclass of: SO_0000010

850593
type: Gene
SIO_000068: ncbigene

position:224326:-1
position: 224326
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:224769:-1
position: 224769
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:224326-224769:-1:exon

YFR033C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: COR3
alternative label: UCR6
gene: QCR6
locus tag: YFR033C
gene synonym: COR3; UCR6
product: ubiquinol--cytochrome-c reductase subunit 6
transcript id: NM_001179998.3
SIO_010081: YFR033C
subclass of: SO_0000673
so part of: YFR033C
location: complement(<224326..>224769)
location: region:224326-224769:-1
so has part: feature:224326-224769:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:224326-224769:-1:exon

YFR033C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: COR3
alternative label: UCR6
gene: QCR6
locus tag: YFR033C
gene synonym: COR3; UCR6
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:11914276|PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005750 mitochondrial respiratory chain complex III [PMID:10873857]
experiment: EXISTENCE:direct assay:GO:0005758 mitochondrial intermembrane space [PMID:22984289]
experiment: EXISTENCE:direct assay:GO:0034399 nuclear periphery [PMID:25817432]
experiment: EXISTENCE:mutant phenotype:GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c [PMID:8288589]
experiment: EXISTENCE:mutant phenotype:GO:0008121 ubiquinol-cytochrome-c reductase activity [PMID:8288589]
experiment: EXISTENCE:mutant phenotype:GO:0009060 aerobic respiration [PMID:8288589]
note: Subunit 6 of the ubiquinol cytochrome-c reductase complex; the complex, also known as the cytochrome bc(1) complex or Complex III, is a component of the mitochondrial inner membrane electron transport chain; highly acidic protein; required for maturation of cytochrome c1; may be loosely associated with the complex since it is easily released into the intermembrane space
codon start: 1
product: ubiquinol--cytochrome-c reductase subunit 6
translation: MGMLELVGEYWEQLKITVVPVVAAAEDDDNEQHEEKAAEGEEKEEENGDEDEDEDEDEDDDDDDDEDEEEEEEVTDQLEDLREHFKNTEEGKALVHHYEECAERVKIQQQQPGYADLEHKEDCVEEFFHLQHYLDTATAPRLFDKLK
SIO_010081: YFR033C
subclass of: SO_0000673
so part of: YFR033C
location: complement(224326..224769)
location: region:224326-224769:-1
so has part: feature:224326-224769:-1:exon

NP_116691.3
type: Protein
SIO_000068: ncbiprotein

S000001929
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:224326-224769:-1:exon

YFR034C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PHO4
locus tag: YFR034C
so part of: sequence
location: complement(<225020..>225958)
location: region:225020-225958:-1
so has part: feature:225020-225958:-1:exon
subclass of: SO_0000010

850594
type: Gene
SIO_000068: ncbigene

position:225020:-1
position: 225020
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:225958:-1
position: 225958
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:225020-225958:-1:exon

YFR034C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PHO4
locus tag: YFR034C
product: phosphate-sensing transcription factor PHO4
transcript id: NM_001179999.1
SIO_010081: YFR034C
subclass of: SO_0000673
so part of: YFR034C
location: complement(<225020..>225958)
location: region:225020-225958:-1
so has part: feature:225020-225958:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:225020-225958:-1:exon

YFR034C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PHO4
locus tag: YFR034C
experiment: EXISTENCE:direct assay:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:18408055]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:10320381]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:10320381]
experiment: EXISTENCE:direct assay:GO:0016036 cellular response to phosphate starvation [PMID:10320381]
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:2183025|PMID:2664469|PMID:19111667|PMID:19158363]
experiment: EXISTENCE:genetic interaction:GO:0045937 positive regulation of phosphate metabolic process [PMID:3915785]
experiment: EXISTENCE:genetic interaction:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:3915785]
experiment: EXISTENCE:mutant phenotype:GO:0003700 DNA-binding transcription factor activity [PMID:2183025]
experiment: EXISTENCE:mutant phenotype:GO:0006338 chromatin remodeling [PMID:2196175]
experiment: EXISTENCE:mutant phenotype:GO:0016036 cellular response to phosphate starvation [PMID:10320381]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:3139496|PMID:4616940]
note: Basic helix-loop-helix (bHLH) transcription factor of the myc-family; activates transcription cooperatively with Pho2p in response to phosphate limitation; binding to 'CACGTG' motif is regulated by chromatin restriction, competitive binding of Cbf1p to the same DNA binding motif and cooperation with Pho2p; function is regulated by phosphorylation at multiple sites and by phosphate availability
codon start: 1
product: phosphate-sensing transcription factor PHO4
translation: MGRTTSEGIHGFVDDLEPKSSILDKVGDFITVNTKRHDGREDFNEQNDELNSQENHNSSENGNENENEQDSLALDDLDRAFELVEGMDMDWMMPSHAHHSPATTATIKPRLLYSPLIHTQSAVPVTISPNLVATATSTTSANKVTKNKSNSSPYLNKRRGKPGPDSATSLFELPDSVIPTPKPKPKPKQYPKVILPSNSTRRVSPVTAKTSSSAEGVVVASESPVIAPHGSSHSRSLSKRRSSGALVDDDKRESHKHAEQARRNRLAVALHELASLIPAEWKQQNVSAAPSKATTVEAACRYIRHLQQNVST
SIO_010081: YFR034C
subclass of: SO_0000673
so part of: YFR034C
location: complement(225020..225958)
location: region:225020-225958:-1
so has part: feature:225020-225958:-1:exon

NP_116692.1
type: Protein
SIO_000068: ncbiprotein

S000001930
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:225020-225958:-1:exon

YFR035C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YFR035C
so part of: sequence
location: complement(<226121..>226465)
location: region:226121-226465:-1
so has part: feature:226121-226465:-1:exon
subclass of: SO_0000010

850595
type: Gene
SIO_000068: ncbigene

position:226121:-1
position: 226121
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:226465:-1
position: 226465
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:226121-226465:-1:exon

YFR035C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YFR035C
product: uncharacterized protein
transcript id: NM_001180000.3
SIO_010081: YFR035C
subclass of: SO_0000673
so part of: YFR035C
location: complement(<226121..>226465)
location: region:226121-226465:-1
so has part: feature:226121-226465:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:226121-226465:-1:exon

YFR035C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YFR035C
note: hypothetical protein; deletion mutant exhibits synthetic phenotype with alpha-synuclein
codon start: 1
product: uncharacterized protein
translation: MSASDKTKLCNKGMSRTSRTTTFVITPAFRERDDEGANSLCKAFLNTFSNLKSGMFKCLLGVGAVGTFISTFPQFFLLPCLLCVRCVCVCLCASISYAASAIFSFSIFFFFCLA
SIO_010081: YFR035C
subclass of: SO_0000673
so part of: YFR035C
location: complement(226121..226465)
location: region:226121-226465:-1
so has part: feature:226121-226465:-1:exon

NP_116693.3
type: Protein
SIO_000068: ncbiprotein

S000001931
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:226121-226465:-1:exon

YNCF0014C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCF0014C
so part of: sequence
location: complement(226688..226760)
location: region:226688-226760:-1
so has part: feature:226688-226760:-1:exon
subclass of: SO_0000663

850596
type: Gene
SIO_000068: ncbigene

position:226688:-1
position: 226688
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:226760:-1
position: 226760
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:226688-226760:-1:exon

YNCF0014C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCF0014C
product: tRNA-Lys
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:8915539]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:8915539]
experiment: EXISTENCE:mutant phenotype:GO:0030533 triplet codon-amino acid adaptor activity [PMID:17560369]
experiment: EXISTENCE:mutant phenotype:GO:0032543 mitochondrial translation [PMID:17560369]
note: Lysine tRNA (tRNA-Lys), predicted by tRNAscan-SE analysis; a small portion is imported into mitochondria via interaction with mt lysyl-tRNA synthetase Msk1p and is necessary to decode AAG codons at high temperature, when base modification of mt-encoded tRNA-Lys is reduced
SIO_010081: YNCF0014C
subclass of: SO_0000673
so part of: YNCF0014C
location: complement(226688..226760)
location: region:226688-226760:-1
so has part: feature:226688-226760:-1:exon

S000006620
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:226688-226760:-1:exon

YFR036W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: HIT3
alternative label: SCD26
gene: CDC26
locus tag: YFR036W
gene synonym: HIT3; SCD26
so part of: sequence
location: <226963..>227337
location: region:226963-227337:1
so has part: feature:226963-227337:1:exon
subclass of: SO_0000010

850597
type: Gene
SIO_000068: ncbigene

position:226963:1
position: 226963
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:227337:1
position: 227337
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:226963-227337:1:exon

YFR036W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: HIT3
alternative label: SCD26
gene: CDC26
locus tag: YFR036W
gene synonym: HIT3; SCD26
product: anaphase promoting complex subunit CDC26
transcript id: NM_001180001.1
SIO_010081: YFR036W
subclass of: SO_0000673
so part of: YFR036W
location: <226963..>227337
location: region:226963-227337:1
so has part: feature:226963-227337:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:226963-227337:1:exon

YFR036W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: HIT3
alternative label: SCD26
gene: CDC26
locus tag: YFR036W
gene synonym: HIT3; SCD26
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0005680 anaphase-promoting complex [PMID:9469814]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0031145 anaphase-promoting complex-dependent catabolic process [PMID:8895471]
experiment: EXISTENCE:genetic interaction:GO:0006325 chromatin organization [PMID:12399376]
experiment: EXISTENCE:mutant phenotype:GO:0016567 protein ubiquitination [PMID:8895471]
experiment: EXISTENCE:mutant phenotype:GO:0061630 ubiquitin protein ligase activity [PMID:8895471]
note: Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C); which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; relocalizes to the cytosol in response to hypoxia
codon start: 1
product: anaphase promoting complex subunit CDC26
translation: MIRRAPTTLQLSHDDVTSLIDDLNEQKLKQQLNIEKTKYFQGKNGGSLHSNTDFQDTSQNIEDNNNDNDNDIDEDDDMSSYNDKAASVAHTRVLNSLHLSTDSNTAHETSNANDNHNPFYIREE
SIO_010081: YFR036W
subclass of: SO_0000673
so part of: YFR036W
location: 226963..227337
location: region:226963-227337:1
so has part: feature:226963-227337:1:exon

NP_116694.1
type: Protein
SIO_000068: ncbiprotein

S000001932
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:226963-227337:1:exon

YFR037C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SWH3
gene: RSC8
locus tag: YFR037C
gene synonym: SWH3
so part of: sequence
location: complement(<227513..>229186)
location: region:227513-229186:-1
so has part: feature:227513-229186:-1:exon
subclass of: SO_0000010

850598
type: Gene
SIO_000068: ncbigene

position:227513:-1
position: 227513
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:229186:-1
position: 229186
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:227513-229186:-1:exon

YFR037C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SWH3
gene: RSC8
locus tag: YFR037C
gene synonym: SWH3
product: Rsc8p
transcript id: NM_001180002.3
SIO_010081: YFR037C
subclass of: SO_0000673
so part of: YFR037C
location: complement(<227513..>229186)
location: region:227513-229186:-1
so has part: feature:227513-229186:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:227513-229186:-1:exon

YFR037C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SWH3
gene: RSC8
locus tag: YFR037C
gene synonym: SWH3
experiment: EXISTENCE:direct assay:GO:0003677 DNA binding [PMID:16461455]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0006303 double-strand break repair via nonhomologous end joining [PMID:15870268]
experiment: EXISTENCE:direct assay:GO:0006337 nucleosome disassembly [PMID:16492771]
experiment: EXISTENCE:direct assay:GO:0006368 transcription elongation by RNA polymerase II promoter [PMID:17081996]
experiment: EXISTENCE:direct assay:GO:0016586 RSC-type complex [PMID:10619019|PMID:12183366]
experiment: EXISTENCE:mutant phenotype:GO:0006303 double-strand break repair via nonhomologous end joining [PMID:15870268]
note: Component of the RSC chromatin remodeling complex; essential for viability and mitotic growth; homolog of SWI/SNF subunit Swi3p, but unlike Swi3p, does not activate transcription of reporters
codon start: 1
product: Rsc8p
translation: MSDTEKDKDVPMVDSHEATEEPPTTSTNTPSFPHLAQEQAKEESATLGAEVAHKKINYEQEAQKLEEKALRFLAKQTHPVIIPSFASWFDISKIHEIEKRSNPDFFNDSSRFKTPKAYKDTRNFIINTYRLSPYEYLTITAVRRNVAMDVASIVKIHAFLEKWGLINYQIDPRTKPSLIGPSFTGHFQVVLDTPQGLKPFLPENVIKQEVEGGDGAEPQVKKEFPVNLTIKKNVYDSAQDFNALQDESRNSRQIHKVYICHTCGNESINVRYHNLRARDTNLCSRCFQEGHFGANFQSSDFIRLENNGNSVKKNWSDQEMLLLLEGIEMYEDQWEKIADHVGGHKRVEDCIEKFLSLPIEDNYIREVVGSTLNGKGGDSRDGSVSGSKLMECVNDAVQTLLQGDDKLGKVSDKSREISEKYIEESQAIIQELVKLTMEKLESKFTKLCDLETQLEMEKLKYVKESEKMLNDRLSLSKQILDLNKSLEELNVSKKLVLISEQVDSGIQLVEKDQEGDDEDGNTATGHGVKRVGKEGEEVGEGDSIAKLQPQVYKPWSL
SIO_010081: YFR037C
subclass of: SO_0000673
so part of: YFR037C
location: complement(227513..229186)
location: region:227513-229186:-1
so has part: feature:227513-229186:-1:exon

NP_116695.3
type: Protein
SIO_000068: ncbiprotein

S000001933
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:227513-229186:-1:exon

YFR038W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: IRC5
locus tag: YFR038W
so part of: sequence
location: <229380..>231941
location: region:229380-231941:1
so has part: feature:229380-231941:1:exon
subclass of: SO_0000010

850599
type: Gene
SIO_000068: ncbigene

position:229380:1
position: 229380
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:231941:1
position: 231941
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:229380-231941:1:exon

YFR038W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: IRC5
locus tag: YFR038W
product: putative ATPase
transcript id: NM_001180003.1
SIO_010081: YFR038W
subclass of: SO_0000673
so part of: YFR038W
location: <229380..>231941
location: region:229380-231941:1
so has part: feature:229380-231941:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:229380-231941:1:exon

YFR038W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: IRC5
locus tag: YFR038W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0006312 mitotic recombination [PMID:18085829]
experiment: EXISTENCE:mutant phenotype:GO:0070987 error-free translesion synthesis [PMID:30111537]
note: Putative ATPase containing the DEAD/H helicase-related sequence motif; null mutant displays increased levels of spontaneous Rad52p foci; SWAT-GFP and mCherry fusion proteins localize to the nucleus
codon start: 1
product: putative ATPase
translation: MSRCSNAALMTVVEDAVGARVAARTRNMSNGVNYREKEVNDLTADISDSDSDLDSEDNKHGKGDNDTAPIWLQDDVHSDEDIQLDSEDDSDTEAVQAQVVDKLAKDTKSEQKSLDDELSEMDTKTVSLKLKKLNEFVRQSQVYSSIIADTLLHRSNEVANANTKDNSNSDDEEHSSKKRKTKKKSITDFFKKQKKNEDTTTQNGAPDDAAIKQPRLLKNCILKPYQLEGLNWLITLYENGLNGILADEMGLGKTVQSIALLAFIYEMDTKGPFLVTAPLSTLDNWMNEFAKFAPDLPVLKYYGTNGYKERSAKLKNFFKQHGGTGIVITSYEIILRDTDLIMSQNWKFLIVDEGHRLKNINCRLIKELKKINTSNRLLLTGTPLQNNLAELWSLLNFIMPDIFADFEIFNKWFDFDSLNLGSGSNSEALNKLINDELQKNLISNLHTILKPFLLRRLKKVVLANILPPKREYIINCPMTSAQEKFYKAGLNGKLKKTMFKELIKDFFTLNDEYIGHVSNRSIRDFINYKLSGNETSNTDNKINPTLLQMDKLYKKNLQMEISNKKLQNMMMQLRQIIDSTFLFYFPYLHPEDLTLETLLKTSGKLQILQKLIPPLISEGHKVLIYSQFVNMLDLIEDWCDLNSFATFRIDGSVNNETRKDQLEKFNSSKDKHNIFLLSTRAAGLGINLVGADTVVLFDSDWNPQVDLQAMDRCHRIGQESPVIVYRLCCDNTIEHVILTRAANKRNLERMVIQMGKFNNLKKLALNEGSFLKANKAGVNVTNKDLVQELSMLLMSDESNIGFENGGQKENKATEGQLTDKEVEELTNRSLEAYKANRVVDLPHVKLFETTSGL
SIO_010081: YFR038W
subclass of: SO_0000673
so part of: YFR038W
location: 229380..231941
location: region:229380-231941:1
so has part: feature:229380-231941:1:exon

NP_116696.2
type: Protein
SIO_000068: ncbiprotein

S000001934
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:229380-231941:1:exon

YFR039C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: OSW7
locus tag: YFR039C
so part of: sequence
location: complement(<232012..>233544)
location: region:232012-233544:-1
so has part: feature:232012-233544:-1:exon
subclass of: SO_0000010

850600
type: Gene
SIO_000068: ncbigene

position:232012:-1
position: 232012
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:233544:-1
position: 233544
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:232012-233544:-1:exon

YFR039C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: OSW7
locus tag: YFR039C
product: Osw7p
transcript id: NM_001180004.3
SIO_010081: YFR039C
subclass of: SO_0000673
so part of: YFR039C
location: complement(<232012..>233544)
location: region:232012-233544:-1
so has part: feature:232012-233544:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:232012-233544:-1:exon

YFR039C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: OSW7
locus tag: YFR039C
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0030476 ascospore wall assembly [PMID:23966878]
note: Protein involved in outer spore wall assembly; likely involved directly in dityrosine layer assembly; may be involved in response to high salt and changes in carbon source; SWAT-GFP, seamless-GFP and mCherry fusion proteins localize to the endoplasmic reticulum; deletion mutant has decreased spore survival in Drosophila feces; OSW7 has a paralog, SHE10, that arose from the whole genome duplication; paralogs are redundant for spore wall dityrosine assembly
codon start: 1
product: Osw7p
translation: MKAVFKVTTALLACVFIARYLVCQQNGLGSFATDLQPICRHTEFSVGSLFDSKLVEGSAVSDYLVGKYSQSIKPLIERYPNSSLKRIMGYFYRFWYNIFSFLRLNELCCSLHSKLGPLLNHLRIAWYYLKPYTDNVKNVLENPFNSSTDWMKYGSFSADGTLTKPIFETDSETEDYEDDENENEDEDEDEDEDDVGIEDENKEYEFDGVQDGHGNSQLVTAAILQDLSKIIIGSNSHAELETYEAESLKMEYEAWIKAIDSKIHSAMALLDSEIQSVFEAEVQNKSIEITRNLDDLNTTVNEQLVFLDSKIKDINCTSKFDPVQNKIKYFDESGQVELEAYITKSSITSILKNYKIHLLDFEKSLFHSLDSFLTEMAKLAESIRLENVEVYEEWGDVMISQWSQRMAYMDVRGLHLEDQYDPAYIEENHSNWLRFMELKKKVISERNRLVKHDLDMTLILEWITKLKADFQNTKNNIQDTFLQRMNTADTLFKNRELKEQLEEEFVRQEH
SIO_010081: YFR039C
subclass of: SO_0000673
so part of: YFR039C
location: complement(232012..233544)
location: region:232012-233544:-1
so has part: feature:232012-233544:-1:exon

NP_116697.3
type: Protein
SIO_000068: ncbiprotein

S000001935
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:232012-233544:-1:exon

YFR040W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SAP155
locus tag: YFR040W
so part of: sequence
location: <234242..>237250
location: region:234242-237250:1
so has part: feature:234242-237250:1:exon
subclass of: SO_0000010

850601
type: Gene
SIO_000068: ncbigene

position:234242:1
position: 234242
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:237250:1
position: 237250
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:234242-237250:1:exon

YFR040W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SAP155
locus tag: YFR040W
product: Sap155p
transcript id: NM_001180005.2
SIO_010081: YFR040W
subclass of: SO_0000673
so part of: YFR040W
location: <234242..>237250
location: region:234242-237250:1
so has part: feature:234242-237250:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:234242-237250:1:exon

YFR040W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SAP155
locus tag: YFR040W
experiment: EXISTENCE:direct assay:GO:1903765 negative regulation of potassium ion export across plasma membrane [PMID:15947196]
experiment: EXISTENCE:mutant phenotype:GO:0000082 G1/S transition of mitotic cell cycle [PMID:8649382]
experiment: EXISTENCE:mutant phenotype:GO:1903765 negative regulation of potassium ion export across plasma membrane [PMID:15947196]
note: Protein required for function of the Sit4p protein phosphatase; forms a complex with Sit4p; member of a family of similar proteins including Sap4p, Sap185p, and Sap190p; protein abundance increases in response to DNA replication stress; SAP155 has a paralog, SAP4, that arose from the whole genome duplication
codon start: 1
product: Sap155p
translation: MSFWPFGQNLNHSNINKILDEYFHVLHELERINPSVGKAIPAIFNNVQERGTSDSLDSIPEEYSHGDEVKTARGDQKSRFEKDDQQERYEKEEEERSMNSSESSTTSFSSGSTSKTDLDEEDISNATAPMMVTTKNLDNSFIERMLVETELLNELSRQNKTLLDFICFGFFFDKKTNKKVNNMEYLVDQLMECISKIKTATTVDLNNLIDYQEQQQLDDSSQEDVYVESDTEQEEEKEDDNNSNNKKRRKRGSSSFGNDDINNNDDDDDANEDDESAYLTKATIISEIFSLDIWLISESLVKNQSYLNKIWSIINQPNFNSENSPLVPIFLKINQNLLLTRQDQYLNFIRTERSFVDDMLKHVDISLLMDFFLKIISTDKIESPTGIIELVYDQNLISKCLSFLNNKESPADIQACVGDFLKALIAISANAPLDDISIGPNSLTRQLASPESIAKLVDIMINQRGAALNTTVSIVIELIRKNNSDYDQVNLLTTTIKTHPPSNRDPIYLGYLLRKFSNHLSDFFQIILDIENDANIPLHENQLHEKFKPLGFERFKVVELIAELLHCSNMGLMNSKRAERIARRRDKVRSQLSHHLQDALNDLSIEEKEQLKTKHSPTRDTDHDLKNNNGKIDNDNNDNDDESDYGDEIDESFEIPYINMKQNIKLRTDPTVGDLFKIKLYDTRIVSKIMELFLTHPWNNFWHNVIFDIIQQIFNGRMDFSYNSFLVLSLFNLKSSYQFMTDIVISDEKGTDVSRFSPVIRDPNFDFKITTDFILRGYQDSYKFYELRKMNLGYMGHIVLIAEEVVKFSKLYKVELISPDIQVILQTEEWQYYSEEVLNETRMMYSKILGGGSYIDDGNGNIIPQLPDNTTVLTPNGDASNNNEILDSDTGSSNGTSGGGQLINVESLEEQLSLSTESDLHNKLREMLINRAQEDVDNKNTENGVFILGPPEDKNSNSNINNTNHNSNNSNNNDNNDNNDNDNDNTRNYNEDADNDNDYDHE
SIO_010081: YFR040W
subclass of: SO_0000673
so part of: YFR040W
location: 234242..237250
location: region:234242-237250:1
so has part: feature:234242-237250:1:exon

NP_116698.3
type: Protein
SIO_000068: ncbiprotein

S000001936
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:234242-237250:1:exon

YFR041C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ERJ5
locus tag: YFR041C
so part of: sequence
location: complement(<237368..>238255)
location: region:237368-238255:-1
so has part: feature:237368-238255:-1:exon
subclass of: SO_0000010

850602
type: Gene
SIO_000068: ncbigene

position:237368:-1
position: 237368
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:238255:-1
position: 238255
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:237368-238255:-1:exon

YFR041C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ERJ5
locus tag: YFR041C
product: Erj5p
transcript id: NM_001180006.3
SIO_010081: YFR041C
subclass of: SO_0000673
so part of: YFR041C
location: complement(<237368..>238255)
location: region:237368-238255:-1
so has part: feature:237368-238255:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:237368-238255:-1:exon

YFR041C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ERJ5
locus tag: YFR041C
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:17157937|PMID:14562095|PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0006457 protein folding [PMID:17157937]
note: Type I membrane protein with a J domain; required to preserve the folding capacity of the endoplasmic reticulum; loss of the non-essential ERJ5 gene leads to a constitutively induced unfolded protein response
codon start: 1
product: Erj5p
translation: MNGYWKPALVVLGLVSLSYAFTTIETEIFQLQNEISTKYGPDMNFYKFLKLPKLQNSSTKEITKNLRKLSKKYHPDKNPKYRKLYERLNLATQILSNSSNRKIYDYYLQNGFPNYDFHKGGFYFSRMKPKTWFLLAFIWIVVNIGQYIISIIQYRSQRSRIENFISQCKQQDDTNGLGVKQLTFKQHEKDEGKSLVVRFSDVYVVEPDGSETLISPDTLDKPSVKNCLFWRIPASVWNMTFGKSVGSAGKEEIITDSKKYDGNQTKKGNKVKKGSAKKGQKKMELPNGKVIYSRK
SIO_010081: YFR041C
subclass of: SO_0000673
so part of: YFR041C
location: complement(237368..238255)
location: region:237368-238255:-1
so has part: feature:237368-238255:-1:exon

NP_116699.3
type: Protein
SIO_000068: ncbiprotein

S000001937
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:237368-238255:-1:exon

YFR042W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: KEG1
locus tag: YFR042W
so part of: sequence
location: <238458..>239060
location: region:238458-239060:1
so has part: feature:238458-239060:1:exon
subclass of: SO_0000010

850603
type: Gene
SIO_000068: ncbigene

position:238458:1
position: 238458
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:239060:1
position: 239060
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:238458-239060:1:exon

YFR042W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: KEG1
locus tag: YFR042W
product: Keg1p
transcript id: NM_001180007.1
SIO_010081: YFR042W
subclass of: SO_0000673
so part of: YFR042W
location: <238458..>239060
location: region:238458-239060:1
so has part: feature:238458-239060:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:238458-239060:1:exon

YFR042W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: KEG1
locus tag: YFR042W
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:17893149]
experiment: EXISTENCE:mutant phenotype:GO:0006078 (1->6)-beta-D-glucan biosynthetic process [PMID:17893149]
experiment: EXISTENCE:mutant phenotype:GO:0051276 chromosome organization [PMID:18439903]
note: Integral membrane protein of the ER; physically interacts with Kre6p; has a role in the synthesis of beta-1,6-glucan in the cell wall; required for cell viability
codon start: 1
product: Keg1p
translation: MAGIKLTHKLYQYYQLATSFLYAALLIRWLILMPLVGSRFLPGGIHEFLIYLMFYSSIMEVIWLLRFHGFKYGLLSRTFLKDLNFIYLVSVIHFYDDYEHALILKNASYSSFIISLSLSQAYCHWCKLFKRKGVKERTLVWKVNTFVTLPILYLSEFALLLLNIQVKNYHSTPTLDIINRVVLLAYFPVLLTAYKKLLTK
SIO_010081: YFR042W
subclass of: SO_0000673
so part of: YFR042W
location: 238458..239060
location: region:238458-239060:1
so has part: feature:238458-239060:1:exon

NP_116700.1
type: Protein
SIO_000068: ncbiprotein

S000001938
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:238458-239060:1:exon

YFR043C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: IRC6
locus tag: YFR043C
so part of: sequence
location: complement(<239114..>239827)
location: region:239114-239827:-1
so has part: feature:239114-239827:-1:exon
subclass of: SO_0000010

850604
type: Gene
SIO_000068: ncbigene

position:239114:-1
position: 239114
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:239827:-1
position: 239827
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:239114-239827:-1:exon

YFR043C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: IRC6
locus tag: YFR043C
product: Irc6p
transcript id: NM_001180008.3
SIO_010081: YFR043C
subclass of: SO_0000673
so part of: YFR043C
location: complement(<239114..>239827)
location: region:239114-239827:-1
so has part: feature:239114-239827:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:239114-239827:-1:exon

YFR043C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: IRC6
locus tag: YFR043C
experiment: EXISTENCE:direct assay:GO:0030674 protein-macromolecule adaptor activity [PMID:22993212]
experiment: EXISTENCE:genetic interaction:GO:0016192 vesicle-mediated transport [PMID:22993212]
experiment: EXISTENCE:physical interaction:GO:0016192 vesicle-mediated transport [PMID:22993212]
note: Clathrin coat accessory factor; involved in clathrin-mediated vesicle trafficking; may function to link the AP-1 clathrin adaptor complex with the Rab GTPase Ypt31p; has structural similarity to G-proteins; mouse homolog Aagab (p34) functionally complements irc6 null mutation; null mutant displays increased levels of spontaneous Rad52p foci
codon start: 1
product: Irc6p
translation: MVLQYPQNKILVLSDHPHNFLKTQFLQDLFHCSSTGISIVKDQTWENRYYKVHFDLYIDSCKEIPVWVEEFITPECEPLRNVMAGIILITDIRQTKPQELLHQFMIAAHRNTFVVLANVNEEVEQDEIDELNEIWSNAFTNVIEFVNWKRSKPTVNHNDYGEKLGLDRIQEIIDTHDWLNCEVQPATKIREEIPNEMPLEQIIRNLQSARLKYKSIENSSEADAFANEMADELSRYL
SIO_010081: YFR043C
subclass of: SO_0000673
so part of: YFR043C
location: complement(239114..239827)
location: region:239114-239827:-1
so has part: feature:239114-239827:-1:exon

NP_116701.3
type: Protein
SIO_000068: ncbiprotein

S000001939
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:239114-239827:-1:exon

YFR044C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: DUG1
locus tag: YFR044C
so part of: sequence
location: complement(<239992..>241437)
location: region:239992-241437:-1
so has part: feature:239992-241437:-1:exon
subclass of: SO_0000010

850605
type: Gene
SIO_000068: ncbigene

position:239992:-1
position: 239992
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:241437:-1
position: 241437
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:239992-241437:-1:exon

YFR044C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: DUG1
locus tag: YFR044C
product: metallodipeptidase
transcript id: NM_001180009.1
SIO_010081: YFR044C
subclass of: SO_0000673
so part of: YFR044C
location: complement(<239992..>241437)
location: region:239992-241437:-1
so has part: feature:239992-241437:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:239992-241437:-1:exon

YFR044C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: DUG1
locus tag: YFR044C
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:17179087|PMID:11914276|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0070573 metallodipeptidase activity [PMID:19346245]
experiment: EXISTENCE:genetic interaction:GO:0008242 omega peptidase activity [PMID:17179087]
experiment: EXISTENCE:mutant phenotype:GO:0006751 glutathione catabolic process [PMID:17179087]
experiment: EXISTENCE:mutant phenotype:GO:0070573 metallodipeptidase activity [PMID:19346245]
note: Cys-Gly metallo-di-peptidase; forms a complex with Dug2p and Dug3p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p); human homolog CNDP2 can complement yeast dug1 mutant
codon start: 1
product: metallodipeptidase
translation: MSHSLTSVFQKIDSLKPQFFSRLTKAIQIPAVSSDESLRSKVFDKAKFISEQLSQSGFHDIKMVDLGIQPPPISTPNLSLPPVILSRFGSDPSKKTVLVYGHYDVQPAQLEDGWDTEPFKLVIDEAKGIMKGRGVTDDTGPLLSWINVVDAFKASGQEFPVNLVTCFEGMEESGSLKLDELIKKEANGYFKGVDAVCISDNYWLGTKKPVLTYGLRGCNYYQTIIEGPSADLHSGIFGGVVAEPMIDLMQVLGSLVDSKGKILIDGIDEMVAPLTEKEKALYKDIEFSVEELNAATGSKTSLYDKKEDILMHRWRYPSLSIHGVEGAFSAQGAKTVIPAKVFGKFSIRTVPDMDSEKLTSLVQKHCDAKFKSLNSPNKCRTELIHDGAYWVSDPFNAQFTAAKKATKLVYGVDPDFTREGGSIPITLTFQDALNTSVLLLPMGRGDDGAHSINEKLDISNFVGGMKTMAAYLQYYSESPEN
SIO_010081: YFR044C
subclass of: SO_0000673
so part of: YFR044C
location: complement(239992..241437)
location: region:239992-241437:-1
so has part: feature:239992-241437:-1:exon

NP_116702.1
type: Protein
SIO_000068: ncbiprotein

S000001940
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:239992-241437:-1:exon

YFR045W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MRX20
locus tag: YFR045W
so part of: sequence
location: <241998..>242999
location: region:241998-242999:1
so has part: feature:241998-242999:1:exon
subclass of: SO_0000010

850606
type: Gene
SIO_000068: ncbigene

position:241998:1
position: 241998
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:242999:1
position: 242999
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:241998-242999:1:exon

YFR045W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MRX20
locus tag: YFR045W
product: Mrx20p
transcript id: NM_001180010.3
SIO_010081: YFR045W
subclass of: SO_0000673
so part of: YFR045W
location: join(<241998..242009,242082..>242999)
location: region:241998-242999:1
so has part: feature:241998-242009:1:exon
so has part: feature:242082-242999:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:241998-242009:1:exon

position:242009:1
position: 242009
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:242082-242999:1:exon

position:242082:1
position: 242082
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YFR045W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MRX20
locus tag: YFR045W
note: Putative mitochondrial transport protein; null mutant is viable, exhibits decreased levels of chitin and normal resistance to calcofluor white
codon start: 1
product: Mrx20p
translation: MANQNSDLYKQITAGSVAAVFQTTMTYPFEYLKTGLQLQPKGTAFEIILPQIKSYFVGCSALNVAAFGKTILRFVTFDKLCHSLNNNIDNNDNFQRLTGYNLLIAGTLTGIVESLFIIPFENIKTTLIQSAMIDHKKLEKNQPVVNAKATFHKVATKSTPVARIEKLLPAVKHMYQTRGPAAFVQGTTATIFRQIANTSIQFTAYTAFKRLLQARNDKASSVITGLATSFTLVAMTQPIDVVKTRMMSQNAKTEYKNTLNCMYRIFVQEGMATFWKGSIFRFMKVGISGGLTFTVYEQVSLLLGFSSRS
SIO_010081: YFR045W
subclass of: SO_0000673
so part of: YFR045W
location: join(241998..242009,242082..242999)
location: region:241998-242999:1
so has part: feature:241998-242009:1:exon
so has part: feature:242082-242999:1:exon

NP_116703.5
type: Protein
SIO_000068: ncbiprotein

S000001941
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:241998-242009:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:242082-242999:1:exon

YFR046C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CNN1
locus tag: YFR046C
so part of: sequence
location: complement(<243074..>244159)
location: region:243074-244159:-1
so has part: feature:243074-244159:-1:exon
subclass of: SO_0000010

850607
type: Gene
SIO_000068: ncbigene

position:243074:-1
position: 243074
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:244159:-1
position: 244159
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:243074-244159:-1:exon

YFR046C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CNN1
locus tag: YFR046C
product: centromere-binding protein CNN1
transcript id: NM_001180011.1
SIO_010081: YFR046C
subclass of: SO_0000673
so part of: YFR046C
location: complement(<243074..>244159)
location: region:243074-244159:-1
so has part: feature:243074-244159:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:243074-244159:-1:exon

YFR046C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CNN1
locus tag: YFR046C
experiment: EXISTENCE:direct assay:GO:0000776 kinetochore [PMID:14633972]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0019237 centromeric DNA binding [PMID:22561345|PMID:22561346]
experiment: EXISTENCE:direct assay:GO:0044877 protein-containing complex binding [PMID:22561345|PMID:22561346]
experiment: EXISTENCE:mutant phenotype:GO:1905560 negative regulation of kinetochore assembly [PMID:22561345]
experiment: EXISTENCE:physical interaction:GO:0007059 chromosome segregation [PMID:14633972|PMID:9520439]
note: Kinetochore protein; associated with the essential kinetochore proteins Nnf1p and Spc24p; phosphorylated by Clb5-Cdk1, Mps1p, Ipl1p and to a lesser extent by Clb2-Cdk1; localizes to the lower region of the Ndc80 complex during anaphase and regulates KMN activity by inhibiting the Mtw1 and Spc105 complexes from binding to the Ndc80 complex; similar to metazoan CENP-T
codon start: 1
product: centromere-binding protein CNN1
translation: MSTPRKAAGNNENTEVSEIRTPFRERALEEQRLKDEVLIRNTPGYRKLLSASTKSHDILNKDPNEVRSFLQDLSQVLARKSQGNDTTTNKTQARNLIDELAYEESQPEENELLRSRSEKLTDNNIGNETQPDYTSLSQTVFAKLQERDKGLKSRKIDPIIIQDVPTTGHEDELTVHSPDKANSISMEVLRTSPSIGMDQVDEPPVRDPVPISITQQEEPLSEDLPSDDKEETEEAENEDYSFENTSDENLDDIGNDPIRLNVPAVRRSSIKPLQIMDLKHLTRQFLNENRIILPKQTWSTIQEESLNIMDFLKQKIGTLQKQELVDSFIDMGIINNVDDMFELAHELLPLELQSRIESYLF
SIO_010081: YFR046C
subclass of: SO_0000673
so part of: YFR046C
location: complement(243074..244159)
location: region:243074-244159:-1
so has part: feature:243074-244159:-1:exon

NP_116704.1
type: Protein
SIO_000068: ncbiprotein

S000001942
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:243074-244159:-1:exon

YFR047C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: QPT1
gene: BNA6
locus tag: YFR047C
gene synonym: QPT1
so part of: sequence
location: complement(<244279..>245166)
location: region:244279-245166:-1
so has part: feature:244279-245166:-1:exon
subclass of: SO_0000010

850608
type: Gene
SIO_000068: ncbigene

position:244279:-1
position: 244279
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:245166:-1
position: 245166
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:244279-245166:-1:exon

YFR047C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: QPT1
gene: BNA6
locus tag: YFR047C
gene synonym: QPT1
product: nicotinate-nucleotide diphosphorylase (carboxylating)
transcript id: NM_001180012.3
SIO_010081: YFR047C
subclass of: SO_0000673
so part of: YFR047C
location: complement(<244279..>245166)
location: region:244279-245166:-1
so has part: feature:244279-245166:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:244279-245166:-1:exon

YFR047C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: QPT1
gene: BNA6
locus tag: YFR047C
gene synonym: QPT1
EC number: 2.4.2.19
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:genetic interaction:GO:0034354 'de novo' NAD biosynthetic process from tryptophan [PMID:12062417]
experiment: EXISTENCE:mutant phenotype:GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity [PMID:12062417]
note: Quinolinate phosphoribosyl transferase; required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expression regulated by Hst1p
codon start: 1
product: nicotinate-nucleotide diphosphorylase (carboxylating)
translation: MPVYEHLLPVNGAWRQDVTNWLSEDVPSFDFGGYVVGSDLKEANLYCKQDGMLCGVPFAQEVFNQCELQVEWLFKEGSFLEPSKNDSGKIVVAKITGPAKNILLAERTALNILSRSSGIATASHKIISLARSTGYKGTIAGTRKTTPGLRRLEKYSMLVGGCDTHRYDLSSMVMLKDNHIWATGSITNAVKNARAVCGFAVKIEVECLSEDEATEAIEAGADVIMLDNFKGDGLKMCAQSLKNKWNGKKHFLLECSGGLNLDNLEEYLCDDIDIYSTSSIHQGTPVIDFSLKLAH
SIO_010081: YFR047C
subclass of: SO_0000673
so part of: YFR047C
location: complement(244279..245166)
location: region:244279-245166:-1
so has part: feature:244279-245166:-1:exon

NP_602317.3
type: Protein
SIO_000068: ncbiprotein

S000001943
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:244279-245166:-1:exon

YFR048W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RMD8
locus tag: YFR048W
so part of: sequence
location: <246146..>248134
location: region:246146-248134:1
so has part: feature:246146-248134:1:exon
subclass of: SO_0000010

850609
type: Gene
SIO_000068: ncbigene

position:246146:1
position: 246146
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:248134:1
position: 248134
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:246146-248134:1:exon

YFR048W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RMD8
locus tag: YFR048W
product: Rmd8p
transcript id: NM_001180013.1
SIO_010081: YFR048W
subclass of: SO_0000673
so part of: YFR048W
location: <246146..>248134
location: region:246146-248134:1
so has part: feature:246146-248134:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:246146-248134:1:exon

YFR048W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RMD8
locus tag: YFR048W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
note: Cytosolic protein required for sporulation
codon start: 1
product: Rmd8p
translation: MSYKANQPSPGEMPKRSPSILVTDARTSKNRMSAPFAGHAAGSRKNMENAGVTKSQGVRSSAIGPSPLQSFTHPRRRSSGRFSDISIDNILSDNSDIPSARREERLSSSSSDRPRQYERLSSRRKMINPLPPRTSKTSQKLVLIPEDDNLNHFQTLPTNALDRQRPKVGSMKSNSFDRLPRYSKEKSMARITAYNVADGFNLNQLYKFLQETHEVSPRLYDECLYVAYTLPLLPGKGGFRIKSNLSKKTMGGKTLIDNLIDTSEQRDHHYEYYSGVETVEDANNNYELETSGNNNNANQDTTTVPDHLPNPVGQQDSFNPMEPQFFAEETPLEIEKRERTERINMLKKEENDSDASCGNDNNNKNNDKSKLYAVEGNDQYVQSSRSPASPSSISTPSPPSSSQNDFDRVYKMHRDNDHEGNDRHAEIFIFHYGVIVFWNFTEIQEKNILGDITFADYKNLMIRPLDEQDIETEQFHFEYDRDTERPRIFNDIVTLRSGDHIIELTLSHAIAQSSKLSRFESRISPILISVTKLPKRLALYGTLGLKREQLLKKSGKLFKLRVDVNLSSTILDTPEFFWSFEPSLHPLYVAMREYLEIDQRVQVLNDRCKVFLEFFDICVDSVAERNMARVTWWFILVILFGVIFSLTEIFVRYVIIHRHTST
SIO_010081: YFR048W
subclass of: SO_0000673
so part of: YFR048W
location: 246146..248134
location: region:246146-248134:1
so has part: feature:246146-248134:1:exon

NP_683716.1
type: Protein
SIO_000068: ncbiprotein

S000001944
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:246146-248134:1:exon

YFR049W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: KGD4
gene: YMR31
locus tag: YFR049W
gene synonym: KGD4
so part of: sequence
location: <248523..>248894
location: region:248523-248894:1
so has part: feature:248523-248894:1:exon
subclass of: SO_0000010

850610
type: Gene
SIO_000068: ncbigene

position:248523:1
position: 248523
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:248894:1
position: 248894
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:248523-248894:1:exon

YFR049W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: KGD4
gene: YMR31
locus tag: YFR049W
gene synonym: KGD4
product: mitochondrial 37S ribosomal protein YMR31
transcript id: NM_001180014.3
SIO_010081: YFR049W
subclass of: SO_0000673
so part of: YFR049W
location: <248523..>248894
location: region:248523-248894:1
so has part: feature:248523-248894:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:248523-248894:1:exon

YFR049W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: KGD4
gene: YMR31
locus tag: YFR049W
gene synonym: KGD4
experiment: EXISTENCE:direct assay:GO:0003735 structural constituent of ribosome [PMID:2693936]
experiment: EXISTENCE:direct assay:GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity [PMID:25165143]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:24769239|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005761 mitochondrial ribosome [PMID:2693936]
experiment: EXISTENCE:direct assay:GO:0009353 mitochondrial oxoglutarate dehydrogenase complex [PMID:25165143]
experiment: EXISTENCE:mutant phenotype:GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity [PMID:25165143]
experiment: EXISTENCE:mutant phenotype:GO:0006099 tricarboxylic acid cycle [PMID:25165143]
experiment: EXISTENCE:mutant phenotype:GO:0006103 2-oxoglutarate metabolic process [PMID:25165143]
note: Subunit of the mitochondrial alpha-ketoglutarate dehydrogenase; recruits E3 subunit (Lpd1p) to the E1-E2 (Kgd1p, Kgd2p) core; exists in two forms derived from a single mRNA translated from two alternative start sites; has similarity to human mitochondrial ribosomal protein MRP-S36
codon start: 1
product: mitochondrial 37S ribosomal protein YMR31
translation: MIATPIRLAKSAYEPMIKFVGTRHPLVKHATEVVVHPCATNGMLPGSKECIPVSKFMENYKPFRVVPIKHSANAGLSSSKTSVFVNRPLQKDELASIFELPARFRYKPINEHELESINSGGAW
SIO_010081: YFR049W
subclass of: SO_0000673
so part of: YFR049W
location: 248523..248894
location: region:248523-248894:1
so has part: feature:248523-248894:1:exon

NP_116707.3
type: Protein
SIO_000068: ncbiprotein

S000001945
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:248523-248894:1:exon

YFR050C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PRE4
locus tag: YFR050C
so part of: sequence
location: complement(<249066..>249866)
location: region:249066-249866:-1
so has part: feature:249066-249866:-1:exon
subclass of: SO_0000010

850611
type: Gene
SIO_000068: ncbigene

position:249066:-1
position: 249066
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:249866:-1
position: 249866
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:249066-249866:-1:exon

YFR050C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PRE4
locus tag: YFR050C
product: proteasome core particle subunit beta 7
transcript id: NM_001180015.1
SIO_010081: YFR050C
subclass of: SO_0000673
so part of: YFR050C
location: complement(<249066..>249866)
location: region:249066-249866:-1
so has part: feature:249066-249866:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:249066-249866:-1:exon

YFR050C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PRE4
locus tag: YFR050C
experiment: EXISTENCE:curator inference:GO:0005634 nucleus [PMID:9087403]
experiment: EXISTENCE:curator inference:GO:0005789 endoplasmic reticulum membrane [PMID:9087403]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0010499 proteasomal ubiquitin-independent protein catabolic process [PMID:19162040]
experiment: EXISTENCE:direct assay:GO:0019774 proteasome core complex, beta-subunit complex [PMID:9087403]
experiment: EXISTENCE:direct assay:GO:0034515 proteasome storage granule [PMID:18504300]
experiment: EXISTENCE:direct assay:GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process [PMID:11545745|PMID:19029916]
experiment: EXISTENCE:genetic interaction:GO:0043248 proteasome assembly [PMID:17911101]
note: Beta 7 subunit of the 20S proteasome
codon start: 1
product: proteasome core particle subunit beta 7
translation: MNHDPFSWGRPADSTYGAYNTQIANAGASPMVNTQQPIVTGTSVISMKYDNGVIIAADNLGSYGSLLRFNGVERLIPVGDNTVVGISGDISDMQHIERLLKDLVTENAYDNPLADAEEALEPSYIFEYLATVMYQRRSKMNPLWNAIIVAGVQSNGDQFLRYVNLLGVTYSSPTLATGFGAHMANPLLRKVVDRESDIPKTTVQVAEEAIVNAMRVLYYRDARSSRNFSLAIIDKNTGLTFKKNLQVENMKWDFAKDIKGYGTQKI
SIO_010081: YFR050C
subclass of: SO_0000673
so part of: YFR050C
location: complement(249066..249866)
location: region:249066-249866:-1
so has part: feature:249066-249866:-1:exon

NP_116708.1
type: Protein
SIO_000068: ncbiprotein

S000001946
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:249066-249866:-1:exon

YFR051C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RET2
locus tag: YFR051C
so part of: sequence
location: complement(<250163..>251803)
location: region:250163-251803:-1
so has part: feature:250163-251803:-1:exon
subclass of: SO_0000010

850612
type: Gene
SIO_000068: ncbigene

position:250163:-1
position: 250163
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:251803:-1
position: 251803
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:250163-251803:-1:exon

YFR051C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RET2
locus tag: YFR051C
product: coatomer subunit delta
transcript id: NM_001180016.3
SIO_010081: YFR051C
subclass of: SO_0000673
so part of: YFR051C
location: complement(<250163..>251803)
location: region:250163-251803:-1
so has part: feature:250163-251803:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:250163-251803:-1:exon

YFR051C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RET2
locus tag: YFR051C
experiment: EXISTENCE:direct assay:GO:0030126 COPI vesicle coat [PMID:21435344]
experiment: EXISTENCE:genetic interaction:GO:0048313 Golgi inheritance [PMID:18595704]
experiment: EXISTENCE:genetic interaction:GO:0090167 Golgi distribution to daughter cells [PMID:18595704]
experiment: EXISTENCE:mutant phenotype:GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport [PMID:8617224]
experiment: EXISTENCE:mutant phenotype:GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [PMID:8617224]
experiment: EXISTENCE:mutant phenotype:GO:0030126 COPI vesicle coat [PMID:8617224]
note: Delta subunit of the coatomer complex (COPI); COPI coats Golgi-derived transport vesicles; involved in retrograde transport between Golgi and ER
codon start: 1
product: coatomer subunit delta
translation: MVVLAASITTRQGKPLLSRQFKDLSKDRVLELLSNFQNLVSEISSDHTFVEDKHVRYVYRPFDNYYIILITNRQSNIIKDLATLNLFSQTINSYLSSFQDQEIFHNAFEILSSFDEIVSMGGYKENLSFTQVQTYLSMESHEERIQEIIERNKEIEATEERKRRAKEIARKEHERKHGFMSSNGDYDGANRFMGSKDPNVTNAINSYYSHASPAAQQSYLQSSHAAAAEVAPVASPMATSQRAGHSATGGMKLGGGAGRRAGAAPRPSAISSASSGTPPPPEEDVPENNGILISIKEVINAEFSRDGTIHSSELKGVLELRINDHDLSHSNLKLADSIDVRDKSFQFKTHPNIDKQSFLSTKLISLRDKSKAFPANDQSLGVLRWRKVAPAEDDSLIPLTLTTWVSPSESQQGFDVIIEYESVLETELADVIFTIPVFPQEPVDINTESSTCSDAEVVNMDQEMGTSIKISKIAANDAGALAFTIEAPYEDALYPMTVSFQESTRDKLAKSFTGMAIQSVVMANDHDQELPYDVITSLKSDEYLVQ
SIO_010081: YFR051C
subclass of: SO_0000673
so part of: YFR051C
location: complement(250163..251803)
location: region:250163-251803:-1
so has part: feature:250163-251803:-1:exon

NP_116709.3
type: Protein
SIO_000068: ncbiprotein

S000001947
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:250163-251803:-1:exon

YFR052W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: NIN1
gene: RPN12
locus tag: YFR052W
gene synonym: NIN1
so part of: sequence
location: <252505..>253329
location: region:252505-253329:1
so has part: feature:252505-253329:1:exon
subclass of: SO_0000010

850613
type: Gene
SIO_000068: ncbigene

position:252505:1
position: 252505
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:253329:1
position: 253329
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:252505-253329:1:exon

YFR052W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: NIN1
gene: RPN12
locus tag: YFR052W
gene synonym: NIN1
product: proteasome regulatory particle lid subunit RPN12
transcript id: NM_001180017.1
SIO_010081: YFR052W
subclass of: SO_0000673
so part of: YFR052W
location: <252505..>253329
location: region:252505-253329:1
so has part: feature:252505-253329:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:252505-253329:1:exon

YFR052W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: NIN1
gene: RPN12
locus tag: YFR052W
gene synonym: NIN1
experiment: EXISTENCE:direct assay:GO:0008541 proteasome regulatory particle, lid subcomplex [PMID:9741626]
experiment: EXISTENCE:direct assay:GO:0034515 proteasome storage granule [PMID:18504300]
experiment: EXISTENCE:mutant phenotype:GO:0006511 ubiquitin-dependent protein catabolic process [PMID:10490625]
note: Subunit of the 19S regulatory particle of the 26S proteasome lid; synthetically lethal with RPT1, which is an ATPase component of the 19S regulatory particle; physically interacts with Nob1p and Rpn3p; protein abundance increases in response to DNA replication stress
codon start: 1
product: proteasome regulatory particle lid subunit RPN12
translation: MPSLAELTKSLSIAFENGDYAACEKLLPPIKIELIKNNLLIPDLSIQNDIYLNDLMITKRILEVGALASIQTFNFDSFENYFNQLKPYYFSNNHKLSESDKKSKLISLYLLNLLSQNNTTKFHSELQYLDKHIKNLEDDSLLSYPIKLDRWLMEGSYQKAWDLLQSGSQNISEFDSFTDILKSAIRDEIAKNTELSYDFLPLSNIKALLFFNNEKETEKFALERNWPIVNSKVYFNNQSKEKADYEDEMMHEEDQKTNIIEKAMDYAISIENIV
SIO_010081: YFR052W
subclass of: SO_0000673
so part of: YFR052W
location: 252505..253329
location: region:252505-253329:1
so has part: feature:252505-253329:1:exon

NP_116710.1
type: Protein
SIO_000068: ncbiprotein

S000001948
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:252505-253329:1:exon

YFR053C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HXK1
locus tag: YFR053C
so part of: sequence
location: complement(<253592..>255049)
location: region:253592-255049:-1
so has part: feature:253592-255049:-1:exon
subclass of: SO_0000010

850614
type: Gene
SIO_000068: ncbigene

position:253592:-1
position: 253592
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:255049:-1
position: 255049
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:253592-255049:-1:exon

YFR053C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HXK1
locus tag: YFR053C
product: hexokinase 1
transcript id: NM_001180018.3
SIO_010081: YFR053C
subclass of: SO_0000673
so part of: YFR053C
location: complement(<253592..>255049)
location: region:253592-255049:-1
so has part: feature:253592-255049:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:253592-255049:-1:exon

YFR053C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: HXK1
locus tag: YFR053C
EC number: 2.7.1.1
experiment: EXISTENCE:direct assay:GO:0004396 hexokinase activity [PMID:12611889|PMID:332086]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11254124]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16962558|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0006013 mannose metabolic process [PMID:332086]
experiment: EXISTENCE:direct assay:GO:0006096 glycolytic process [PMID:332086]
experiment: EXISTENCE:genetic interaction:GO:0046323 glucose import [PMID:6300872]
experiment: EXISTENCE:genetic interaction:GO:1990539 fructose import across plasma membrane [PMID:6300872]
experiment: EXISTENCE:mutant phenotype:GO:0004396 hexokinase activity [PMID:6341351]
experiment: EXISTENCE:mutant phenotype:GO:0006000 fructose metabolic process [PMID:6300872]
experiment: EXISTENCE:mutant phenotype:GO:0006006 glucose metabolic process [PMID:6300872]
note: Hexokinase isoenzyme 1; a cytosolic protein that catalyzes phosphorylation of glucose during glucose metabolism; expression is highest during growth on non-glucose carbon sources; glucose-induced repression involves hexokinase Hxk2p; HXK1 has a paralog, HXK2, that arose from the whole genome duplication
codon start: 1
product: hexokinase 1
translation: MVHLGPKKPQARKGSMADVPKELMDEIHQLEDMFTVDSETLRKVVKHFIDELNKGLTKKGGNIPMIPGWVMEFPTGKESGNYLAIDLGGTNLRVVLVKLSGNHTFDTTQSKYKLPHDMRTTKHQEELWSFIADSLKDFMVEQELLNTKDTLPLGFTFSYPASQNKINEGILQRWTKGFDIPNVEGHDVVPLLQNEISKRELPIEIVALINDTVGTLIASYYTDPETKMGVIFGTGVNGAFYDVVSDIEKLEGKLADDIPSNSPMAINCEYGSFDNEHLVLPRTKYDVAVDEQSPRPGQQAFEKMTSGYYLGELLRLVLLELNEKGLMLKDQDLSKLKQPYIMDTSYPARIEDDPFENLEDTDDIFQKDFGVKTTLPERKLIRRLCELIGTRAARLAVCGIAAICQKRGYKTGHIAADGSVYNKYPGFKEAAAKGLRDIYGWTGDASKDPITIVPAEDGSGAGAAVIAALSEKRIAEGKSLGIIGA
SIO_010081: YFR053C
subclass of: SO_0000673
so part of: YFR053C
location: complement(253592..255049)
location: region:253592-255049:-1
so has part: feature:253592-255049:-1:exon

NP_116711.3
type: Protein
SIO_000068: ncbiprotein

S000001949
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:253592-255049:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS609; Autonomously replicating sequence on Chromosome VI; activated very late in S phase in 37% of cell cycles; this origin is specifically fired in the absence of RAD53 in the presence of hydroxyurea
so part of: sequence
location: 256277..256431
location: region:256277-256431:1
so has part: feature:256277-256431:1:region

S000007641
type: SGD
SIO_000068: sgd

position:256277:1
position: 256277
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:256431:1
position: 256431
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:256277-256431:1:region

YFR054C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YFR054C
so part of: sequence
location: complement(<258855..>259433)
location: region:258855-259433:-1
so has part: feature:258855-259433:-1:exon
subclass of: SO_0000010

850615
type: Gene
SIO_000068: ncbigene

position:258855:-1
position: 258855
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:259433:-1
position: 259433
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:258855-259433:-1:exon

YFR054C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YFR054C
product: uncharacterized protein
transcript id: NM_001348833.1
SIO_010081: YFR054C
subclass of: SO_0000673
so part of: YFR054C
location: complement(<258855..>259433)
location: region:258855-259433:-1
so has part: feature:258855-259433:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:258855-259433:-1:exon

YFR054C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YFR054C
note: hypothetical protein; conserved among S. cerevisiae strains
codon start: 1
product: uncharacterized protein
translation: MLFAYSGCLAPQCIPDISSFKALPFRDTESRFTTDSSVISSRFSSSFTSSSSKIIIITSIFSSKMDNEHVGASLIVSLSMASLILTNVFSFSSTSYSSQPSDYIACSPSGIDDQPVAEPSGYTPVGSSSPHSGCITSGLDAIGYQSSLNEGQSTNASSRFVTKVYSHSALTHIILHLLSILQKFYLQVSTIS
SIO_010081: YFR054C
subclass of: SO_0000673
so part of: YFR054C
location: complement(258855..259433)
location: region:258855-259433:-1
so has part: feature:258855-259433:-1:exon

NP_001335774.1
type: Protein
SIO_000068: ncbiprotein

S000001950
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:258855-259433:-1:exon

YFR055W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: IRC7
locus tag: YFR055W
so part of: sequence
location: <264204..>265226
location: region:264204-265226:1
so has part: feature:264204-265226:1:exon
subclass of: SO_0000010

850616
type: Gene
SIO_000068: ncbigene

position:264204:1
position: 264204
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:265226:1
position: 265226
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:264204-265226:1:exon

YFR055W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: IRC7
locus tag: YFR055W
product: cysteine-S-conjugate beta-lyase IRC7
transcript id: NM_001180021.1
SIO_010081: YFR055W
subclass of: SO_0000673
so part of: YFR055W
location: <264204..>265226
location: region:264204-265226:1
so has part: feature:264204-265226:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:264204-265226:1:exon

YFR055W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: IRC7
locus tag: YFR055W
EC number: 4.4.1.13
experiment: EXISTENCE:direct assay:GO:0006790 sulfur compound metabolic process [PMID:21569935]
experiment: EXISTENCE:direct assay:GO:0019450 L-cysteine catabolic process to pyruvate [PMID:21569935]
experiment: EXISTENCE:direct assay:GO:0047804 cysteine-S-conjugate beta-lyase activity [PMID:21569935]
experiment: EXISTENCE:mutant phenotype:GO:0006790 sulfur compound metabolic process [PMID:21569935]
experiment: EXISTENCE:mutant phenotype:GO:0019450 L-cysteine catabolic process to pyruvate [PMID:21569935]
experiment: EXISTENCE:mutant phenotype:GO:0047804 cysteine-S-conjugate beta-lyase activity [PMID:21569935]
note: Cysteine desulphydrase, enables growth on cysteine as nitrogen source; involved in the production of thiols; null mutant displays increased levels of spontaneous Rad52p foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner and by copper levels in a Mac1-dependent manner
codon start: 1
product: cysteine-S-conjugate beta-lyase IRC7
translation: MIDRTELSKFGITTQLSVIGRNPDEQSGFVNPPLYKGSTIILKKLSDLEQRKGRFYGTAGSPTIDNLENAWTHLTGGAGTVLSASGLGSISLALLALSKAGDHILMTDSVYVPTRMLCDGLLAKFGVETDYYDPSIGKDIEKLVKPNTTVIFLESPGSGTMEVQDIPALVSVAKKHGIKTILDNTWATPLFFDAHAHGIDISVEAGTKYLGGHSDLLIGLASANEECWPLLRSTYDAMAMLPGAEDCQLALRGMRTLHLRLKEVERKALDLAAWLGNRDEVEKVLHPAFEDCPGHEYWVRDYKGSSGLFSIVLKNGFTRAGLEKMVEGMKVLQLGFSWGG
SIO_010081: YFR055W
subclass of: SO_0000673
so part of: YFR055W
location: 264204..265226
location: region:264204-265226:1
so has part: feature:264204-265226:1:exon

NP_116714.1
type: Protein
SIO_000068: ncbiprotein

S000001952
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:264204-265226:1:exon

YFR057W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YFR057W
so part of: sequence
location: <269061..>269516
location: region:269061-269516:1
so has part: feature:269061-269516:1:exon
subclass of: SO_0000010

850618
type: Gene
SIO_000068: ncbigene

position:269061:1
position: 269061
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:269516:1
position: 269516
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:269061-269516:1:exon

YFR057W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YFR057W
product: uncharacterized protein
transcript id: NM_001180022.3
SIO_010081: YFR057W
subclass of: SO_0000673
so part of: YFR057W
location: <269061..>269516
location: region:269061-269516:1
so has part: feature:269061-269516:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:269061-269516:1:exon

YFR057W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YFR057W
note: Telomere-linked gene, silencing of which is strictly Sir2-dependent
codon start: 1
product: uncharacterized protein
translation: MIFGPTSVYSKCSAKSSGIIKDTAKLPISRVRIKVMLEITVSFLFFDRFPRSFLNHNLYDSICPFFAWQYTSYYLSIYRQSFLFHFLQKDFSNDFVSEELIYALVALGAKNSFDNSLSKHTYEYYNHSKRNLLEDSTNKNSAFSSASVTKP
SIO_010081: YFR057W
subclass of: SO_0000673
so part of: YFR057W
location: 269061..269516
location: region:269061-269516:1
so has part: feature:269061-269516:1:exon

NP_116715.3
type: Protein
SIO_000068: ncbiprotein

S000001953
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:269061-269516:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS610; Autonomously Replicating Sequence
so part of: sequence
location: 269417..270035
location: region:269417-270035:1
so has part: feature:269417-270035:1:region

S000121260
type: SGD
SIO_000068: sgd

position:269417:1
position: 269417
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:270035:1
position: 270035
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:269417-270035:1:region

telomere
type: Telomere
subclass of: SO_0000624
RO_0002162: 559292
note: TEL06R; Telomeric region on the right arm of Chromosome VI; composed of an X element core sequence and a short terminal stretch of telomeric repeats
so part of: sequence
location: 269731..270161
location: region:269731-270161:1
so has part: feature:269731-270161:1:region

S000028957
type: SGD
SIO_000068: sgd

position:269731:1
position: 269731
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:269731-270161:1:region