Saccharomyces cerevisiae S288C chromosome III, complete sequence.
type: Entry
definition: Saccharomyces cerevisiae S288C chromosome III, complete sequence.
sequence version: NC_001135.5
sequence date: 2023-01-18
sequence: sequence
division: CON
label: NC_001135.5
type: RefSeq
SIO_000068: refseq
dblink: PRJNA128
keyword: RefSeq
source: Saccharomyces cerevisiae S288C
organism: Saccharomyces cerevisiae S288C
taxonomy: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
reference: 1
references: 34897464
reference: 2
references: 8849441
reference: 3
references: 1574125
reference: 4
reference: 5
reference: 6
reference: 7
reference: 8
reference: 9
comment: REVIEWED REFSEQ: This record has been curated by SGD. The reference\nsequence is identical to BK006937.\n\nOn Apr 26, 2011 this sequence version replaced NC_001135.4.\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: SGD\nAnnotation Status :: Full Annotation\nAnnotation Version :: R64-3-1\nURL :: http://www.yeastgenome.org/\n##Genome-Annotation-Data-END##\nCOMPLETENESS: full length.

sequence
subclass of: SO_0000340
sequence length: 316620
topology: linear
so has quality: SO_0000987
location: 1..316620
location: region:1-316620:1
RO_0002162: 559292

NC_001135
type: RefSeq
SIO_000068: refseq

PRJNA128
type: BioProject
SIO_000068: bioproject

1
title: New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources
author: Engel, S.R.
author: Wong, E.D.
author: Nash, R.S.
author: Aleksander, S.
author: Alexander, M.
author: Douglass, E.
author: Karra, K.
author: Miyasato, S.R.
author: Simison, M.
author: Skrzypek, M.S.
author: Weng, S.
author: Cherry, J.M.
journal: Genetics 220 (4) (2022)
pubmed: 34897464

34897464
type: PubMed
SIO_000068: pubmed

2
title: Life with 6000 genes
author: Goffeau, A.
author: Barrell, B.G.
author: Bussey, H.
author: Davis, R.W.
author: Dujon, B.
author: Feldmann, H.
author: Galibert, F.
author: Hoheisel, J.D.
author: Jacq, C.
author: Johnston, M.
author: Louis, E.J.
author: Mewes, H.W.
author: Murakami, Y.
author: Philippsen, P.
author: Tettelin, H.
author: Oliver, S.G.
journal: Science 274 (5287), 546 (1996)
pubmed: 8849441

8849441
type: PubMed
SIO_000068: pubmed

3
title: The complete DNA sequence of yeast chromosome III
author: Oliver, S.G.
author: van der Aart, Q.J.
author: Agostoni-Carbone, M.L.
author: Aigle, M.
author: Alberghina, L.
author: Alexandraki, D.
author: Antoine, G.
author: Anwar, R.
author: Ballesta, J.P.
author: Benit, P. et al.
journal: Nature
volume: 357
issue: 6373
pages: 38-46
year: 1992
pubmed: 1574125

1574125
type: PubMed
SIO_000068: pubmed

4
title: Direct Submission
journal: Submitted (13-JAN-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA

5
title: Direct Submission
journal: Submitted (16-JAN-2015) Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA
comments: Protein update by submitter

6
title: Direct Submission
journal: Submitted (12-APR-2011) Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA
comments: Sequence update by submitter

7
title: Direct Submission
journal: Submitted (27-MAY-2010) Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA
comments: Protein update by submitter

8
title: Direct Submission
journal: Submitted (21-MAY-2010) Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA
comments: Protein update by submitter

9
title: Direct Submission
journal: Submitted (11-DEC-2009) Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA

position:1:1
position: 1
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:316620:1
position: 316620
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

feature:1-316620:1:source
so part of: sequence
organism: Saccharomyces cerevisiae S288C
mol type: genomic DNA
strain: S288C
chromosome: III

559292
type: Taxonomy
SIO_000068: taxonomy

telomere
type: Telomere
subclass of: SO_0000624
RO_0002162: 559292
note: TEL03L; Telomeric region on the left arm of Chromosome III; composed of an X element core sequence, X element combinatorial repeats, and a terminal stretch of telomeric repeats
so part of: sequence
location: complement(1..1098)
location: region:1-1098:-1
so has part: feature:1-1098:-1:region

S000028871
type: SGD
SIO_000068: sgd

position:1:-1
position: 1
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:1098:-1
position: 1098
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:1-1098:-1:region

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS300; Autonomously Replicating Sequence
so part of: sequence
location: 989..1068
location: region:989-1068:1
so has part: feature:989-1068:1:region

S000028476
type: SGD
SIO_000068: sgd

position:989:1
position: 989
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:1068:1
position: 1068
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:989-1068:1:region

mobile_element
type: Mobile Element
subclass of: SO_0001037
RO_0002162: 559292
note: YCLWTy5-1; Ty5 element, LTR retrotransposon of the Copia (Pseudoviridae) group; this is the only near-full length Ty5 retrotransposon in S288C and it is non-functional
mobile element type: retrotransposon:YCLWTy5-1
so part of: sequence
location: 1179..4322
location: region:1179-4322:1
so has part: feature:1179-4322:1:region

S000006831
type: SGD
SIO_000068: sgd

position:1179:1
position: 1179
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:4322:1
position: 4322
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:1179-4322:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty5 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 1179..1429
location: region:1179-1429:1
so has part: feature:1179-1429:1:region

S000006828
type: SGD
SIO_000068: sgd

position:1429:1
position: 1429
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:1179-1429:1:region

YCL075W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCL075W
note: Pseudogene: encodes fragment of Ty Pol protein
pseudo: true
so part of: sequence
location: 2126..2566
location: region:2126-2566:1
so has part: feature:2126-2566:1:exon

850287
type: Gene
SIO_000068: ncbigene

S000000580
type: SGD
SIO_000068: sgd

position:2126:1
position: 2126
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:2566:1
position: 2566
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:2126-2566:1:exon

YCL075W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCL075W
pseudo: true
SIO_010081: YCL075W
subclass of: SO_0000673
so part of: YCL075W
location: 2126..2566
location: region:2126-2566:1
so has part: feature:2126-2566:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:2126-2566:1:exon

YCL074W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCL074W
note: Pseudogene: encodes fragment of Ty Pol protein
pseudo: true
so part of: sequence
location: 2824..3750
location: region:2824-3750:1
so has part: feature:2824-3750:1:exon

850288
type: Gene
SIO_000068: ncbigene

S000000579
type: SGD
SIO_000068: sgd

position:2824:1
position: 2824
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:3750:1
position: 3750
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:2824-3750:1:exon

YCL074W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCL074W
pseudo: true
SIO_010081: YCL074W
subclass of: SO_0000673
so part of: YCL074W
location: 2824..3750
location: region:2824-3750:1
so has part: feature:2824-3750:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:2824-3750:1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty5 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 4073..4322
location: region:4073-4322:1
so has part: feature:4073-4322:1:region

S000006829
type: SGD
SIO_000068: sgd

position:4073:1
position: 4073
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:4073-4322:1:region

YCL073C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GEX1
locus tag: YCL073C
so part of: sequence
location: complement(<6479..>8326)
location: region:6479-8326:-1
so has part: feature:6479-8326:-1:exon
subclass of: SO_0000010

850289
type: Gene
SIO_000068: ncbigene

position:6479:-1
position: 6479
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:8326:-1
position: 8326
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:6479-8326:-1:exon

YCL073C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GEX1
locus tag: YCL073C
product: glutathione exchanger
transcript id: NM_001178711.1
SIO_010081: YCL073C
subclass of: SO_0000673
so part of: YCL073C
location: complement(<6479..>8326)
location: region:6479-8326:-1
so has part: feature:6479-8326:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:6479-8326:-1:exon

YCL073C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GEX1
locus tag: YCL073C
experiment: EXISTENCE:direct assay:GO:0005774 vacuolar membrane [PMID:21490148]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:21490148]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0015299 solute:proton antiporter activity [PMID:21490148]
experiment: EXISTENCE:mutant phenotype:GO:0034775 glutathione transmembrane transport [PMID:21490148]
note: Proton:glutathione antiporter; localized to the vacuolar and plasma membranes; imports glutathione from the vacuole and exports it through the plasma membrane; has a role in resistance to oxidative stress and modulation of the PKA pathway; GEX1 has a paralog, GEX2, that arose from a segmental duplication
codon start: 1
product: glutathione exchanger
translation: MSSSVVGASSNKKSGIRQSCEIIERERHSNDDTYSMTSTFFKLKENEIMSAQFDSLKYKILLISTAFVCGFGISLDYTLRSTYTGYATNSYSEHSLLSTVQVINAVVSVGSQVVYSRLSDHFGRLRLFLVATIFYIMGTIIQSQATRLTMYAAGSVFYNCGYVGTNLLLTLILSDFSSLKWRMFYQYASYWPYIIIPWISGNIITAANPQKNWSWNIAMWAFIYPLSALPIIFLILYMKYKSSKTAEWRSLKEQARKERTGGLFENLVFLFWKLDIVGILLITVSLGCILVPLTLANETSQKWHNSKIIATLVSGGCLFFIFLYWEAKFAKSPLLPFKLLSDRGIWAPLGVTFFNFFTFFISCDYLYPVLLVSMKESSTSAARIVNLPDFVAATASPFYSLLVAKTRKLKLSVIGGCAAWMVCMGLFYKYRGGSGSHEGVIAASVIMGLSGLLCSNSVIVILQAMTTHSRMAVITGIQYTFSKLGAAIGASVSGAIWTQTMPNQLYKNLGNDTLAEIAYASPYTFISDYPWGSPERDAVVESYRYVQRIIMTVGLACTVPFFAFTMFMRDPELIDKATHEEFTEDGLVVLPDEENIFSQIKALFRHNRSNKKLGC
SIO_010081: YCL073C
subclass of: SO_0000673
so part of: YCL073C
location: complement(6479..8326)
location: region:6479-8326:-1
so has part: feature:6479-8326:-1:exon

NP_009863.2
type: Protein
SIO_000068: ncbiprotein

S000000575
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:6479-8326:-1:exon

YCL069W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: VBA3
locus tag: YCL069W
so part of: sequence
location: <9706..>11082
location: region:9706-11082:1
so has part: feature:9706-11082:1:exon
subclass of: SO_0000010

850290
type: Gene
SIO_000068: ncbigene

position:9706:1
position: 9706
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:11082:1
position: 11082
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:9706-11082:1:exon

YCL069W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: VBA3
locus tag: YCL069W
product: basic amino acid transporter
transcript id: NM_001178710.1
SIO_010081: YCL069W
subclass of: SO_0000673
so part of: YCL069W
location: <9706..>11082
location: region:9706-11082:1
so has part: feature:9706-11082:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:9706-11082:1:exon

YCL069W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: VBA3
locus tag: YCL069W
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:15572352]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0015174 basic amino acid transmembrane transporter activity [PMID:15572352]
experiment: EXISTENCE:direct assay:GO:0055085 transmembrane transport [PMID:15572352]
experiment: EXISTENCE:mutant phenotype:GO:0015174 basic amino acid transmembrane transporter activity [PMID:15572352]
experiment: EXISTENCE:mutant phenotype:GO:0015802 basic amino acid transport [PMID:15572352]
experiment: EXISTENCE:mutant phenotype:GO:0055085 transmembrane transport [PMID:15572352]
note: Permease of basic amino acids in the vacuolar membrane; VBA3 has a paralog, VBA5, that arose from a segmental duplication
codon start: 1
product: basic amino acid transporter
translation: MNMLIVGRVVASVGGSGLQTLCFVIGCTMVGERSRPLVISILSCAFAVAAIVGPIIGGAFTTHVTWRWCFYINLPIGGLAIIMFLLTYKAENKGILQQIKDAIGTISSFTFSKFRHQVNFKRLMNGIIFKFDFFGFALCSAGLVLFLLGLTFGGNKYSWNSGQVIAYLVLGVLLFIFSLVYDFFLFDKFNPEPDNISYRPLLLRRLVAKPAIIIINMVTFLLCTGYNGQMIYSVQFFQLIFASSAWKAGLHLIPIVITNVIAAIASGVITKKLGLVKPLLIFGGVLGVIGAGLMTLMTNTSTKSTQIGVLLLPGFSLGFALQASLMSAQLQITKDRPEAAMDFIEVTAFNTFMKSLGTTLGGVLSTTVFSASFHNKVSRAHLEPYEGKTVDDMILYRLQNYDGSHSTIGNILSDSIKNVFWMDLGFYALGFLFCSFSSNKKLIIPKKDETPEDNLEDK
SIO_010081: YCL069W
subclass of: SO_0000673
so part of: YCL069W
location: 9706..11082
location: region:9706-11082:1
so has part: feature:9706-11082:1:exon

NP_009864.1
type: Protein
SIO_000068: ncbiprotein

S000000574
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:9706-11082:1:exon

misc_feature
type: Miscellaneous Feature
subclass of: SO_0000001
RO_0002162: 559292
note: HML; Mating type cassette - left; unexpressed complete copy of the mating-type genes, silenced by the Sir2 histone deacetylase and its associated SIR1, SIR3 and SIR4 proteins; mating-type switching involves replacement of the Ya or Yalpha sequences present at the MAT locus with either the a or alpha genes located at one of the HM loci in a process stimulated by the HO endonuclease; sequence replacement occurs by gene conversion, leaving the donor unaltered
so part of: sequence
location: 11146..14849
location: region:11146-14849:1
so has part: feature:11146-14849:1:region

S000029214
type: SGD
SIO_000068: sgd

position:11146:1
position: 11146
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:14849:1
position: 14849
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:11146-14849:1:region

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS301; Inactive replication origin linked to the silent mating type locus HML; functions as a transcriptional silencer
so part of: sequence
location: 11146..11401
location: region:11146-11401:1
so has part: feature:11146-11401:1:region

S000028477
type: SGD
SIO_000068: sgd

position:11401:1
position: 11401
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:11146-11401:1:region

YCL068C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCL068C
so part of: sequence
location: complement(<11503..>12285)
location: region:11503-12285:-1
so has part: feature:11503-12285:-1:exon
subclass of: SO_0000010

850291
type: Gene
SIO_000068: ncbigene

position:11503:-1
position: 11503
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:12285:-1
position: 12285
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:11503-12285:-1:exon

YCL068C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCL068C
product: uncharacterized protein
transcript id: NM_001178709.1
SIO_010081: YCL068C
subclass of: SO_0000673
so part of: YCL068C
location: complement(<11503..>12285)
location: region:11503-12285:-1
so has part: feature:11503-12285:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:11503-12285:-1:exon

YCL068C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YCL068C
codon start: 1
product: uncharacterized protein
translation: MFVLIDNVLAYLLEQDDLFVTARFAIQGQIVSRRVNKIHISNITDVLLQQFISHTLPYNDNIVPKKILDSMRTAVRQLLEATACVSRECPLVKRSQDIKRARKRLLSDWYRLGADANMDAVLLVVNSAWRFLAVWRPFVNSIQHATQELYQNIAHYLLHGNVNIQRVTALLQLVMGQDDLLFSMDDVLQEVFRIQLYLNKMLPHNSHKWQKPSPFDSANLLLNFRDWTTDNALLQELLLSYPTINKNKHKNHSVPRLIQV
SIO_010081: YCL068C
subclass of: SO_0000673
so part of: YCL068C
location: complement(11503..12285)
location: region:11503-12285:-1
so has part: feature:11503-12285:-1:exon

NP_009865.2
type: Protein
SIO_000068: ncbiprotein

S000000573
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:11503-12285:-1:exon

YCL067C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ALPHA2
gene: HMLALPHA2
locus tag: YCL067C
gene synonym: ALPHA2
so part of: sequence
location: complement(<12386..>13018)
location: region:12386-13018:-1
so has part: feature:12386-13018:-1:exon
subclass of: SO_0000010

850292
type: Gene
SIO_000068: ncbigene

position:12386:-1
position: 12386
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:13018:-1
position: 13018
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:12386-13018:-1:exon

YCL067C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ALPHA2
gene: HMLALPHA2
locus tag: YCL067C
gene synonym: ALPHA2
product: homeodomain mating type protein alpha2
transcript id: NM_001178708.1
SIO_010081: YCL067C
subclass of: SO_0000673
so part of: YCL067C
location: complement(<12386..>13018)
location: region:12386-13018:-1
so has part: feature:12386-13018:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:12386-13018:-1:exon

YCL067C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ALPHA2
gene: HMLALPHA2
locus tag: YCL067C
gene synonym: ALPHA2
note: Silenced copy of ALPHA2 at HML; homeobox-domain protein that associates with Mcm1p in haploid cells to repress a-specific gene expression and interacts with a1p in diploid cells to repress haploid-specific gene expression
codon start: 1
product: homeodomain mating type protein alpha2
translation: MNKIPIKDLLNPQITDEFKSSILDINKKLFSICCNLPKLPESVTTEEEVELRDILGFLSRANKNRKISDEEKKLLQTTSQLTTTITVLLKEMRSIENDRSNYQLTQKNKSADGLVFNVVTQDMINKSTKPYRGHRFTKENVRILESWFAKNIENPYLDTKGLENLMKNTSLSRIQIKNWVSNRRRKEKTITIAPELADLLSGEPLAKKKE
SIO_010081: YCL067C
subclass of: SO_0000673
so part of: YCL067C
location: complement(12386..13018)
location: region:12386-13018:-1
so has part: feature:12386-13018:-1:exon

NP_009866.1
type: Protein
SIO_000068: ncbiprotein

S000000572
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:12386-13018:-1:exon

YCL066W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ALPHA1
gene: HMLALPHA1
locus tag: YCL066W
gene synonym: ALPHA1
so part of: sequence
location: <13282..>13809
location: region:13282-13809:1
so has part: feature:13282-13809:1:exon
subclass of: SO_0000010

850293
type: Gene
SIO_000068: ncbigene

position:13282:1
position: 13282
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:13809:1
position: 13809
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:13282-13809:1:exon

YCL066W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ALPHA1
gene: HMLALPHA1
locus tag: YCL066W
gene synonym: ALPHA1
product: transcriptional co-activator mating type protein alpha
transcript id: NM_001178707.1
SIO_010081: YCL066W
subclass of: SO_0000673
so part of: YCL066W
location: <13282..>13809
location: region:13282-13809:1
so has part: feature:13282-13809:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:13282-13809:1:exon

YCL066W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ALPHA1
gene: HMLALPHA1
locus tag: YCL066W
gene synonym: ALPHA1
note: Silenced copy of ALPHA1 at HML; ALPHA1 encodes a transcriptional coactivator involved in the regulation of mating-type alpha-specific gene expression
codon start: 1
product: transcriptional co-activator mating type protein alpha
translation: MFTSKPAFKIKNKASKSYRNTAVSKKLKEKRLAEHVRPSCFNIIRPLKKDIQIPVPSSRFLNKIQIHRIASGSQNTQFRQFNKTSIKSSKKYLNSFMAFRAYYSQFGSGVKQNVLSSLLAEEWHADKMQHGIWDYFAQQYNFINPGFGFVEWLTNNYAEVRGDGYWEDVFVHLAL
SIO_010081: YCL066W
subclass of: SO_0000673
so part of: YCL066W
location: 13282..13809
location: region:13282-13809:1
so has part: feature:13282-13809:1:exon

NP_009867.1
type: Protein
SIO_000068: ncbiprotein

S000000571
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:13282-13809:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS302; Inactive replication origin linked to the silent mating type locus HML; functions as a transcriptional silencer
so part of: sequence
location: 14575..14849
location: region:14575-14849:1
so has part: feature:14575-14849:1:region

S000028478
type: SGD
SIO_000068: sgd

position:14575:1
position: 14575
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:14575-14849:1:region

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS303; Autonomously Replicating Sequence on Chromosome III; inactive as replication origin at native locus near HML
so part of: sequence
location: 14871..15213
location: region:14871-15213:1
so has part: feature:14871-15213:1:region

S000028479
type: SGD
SIO_000068: sgd

position:14871:1
position: 14871
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:15213:1
position: 15213
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:14871-15213:1:region

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS320; Autonomously Replicating Sequence on Chromosome III; inactive as replication origin at native locus near HML
so part of: sequence
location: 15214..16274
location: region:15214-16274:1
so has part: feature:15214-16274:1:region

S000028480
type: SGD
SIO_000068: sgd

position:15214:1
position: 15214
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:16274:1
position: 16274
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:15214-16274:1:region

YCL064C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CHA1
locus tag: YCL064C
so part of: sequence
location: complement(<15798..>16880)
location: region:15798-16880:-1
so has part: feature:15798-16880:-1:exon
subclass of: SO_0000010

850295
type: Gene
SIO_000068: ncbigene

position:15798:-1
position: 15798
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:16880:-1
position: 16880
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:15798-16880:-1:exon

YCL064C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CHA1
locus tag: YCL064C
product: L-serine/L-threonine ammonia-lyase CHA1
transcript id: NM_001178706.1
SIO_010081: YCL064C
subclass of: SO_0000673
so part of: YCL064C
location: complement(<15798..>16880)
location: region:15798-16880:-1
so has part: feature:15798-16880:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:15798-16880:-1:exon

YCL064C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CHA1
locus tag: YCL064C
EC number: 4.3.1.17
EC number: 4.3.1.19
experiment: EXISTENCE:direct assay:GO:0003941 L-serine ammonia-lyase activity [PMID:7042346]
experiment: EXISTENCE:direct assay:GO:0004794 L-threonine ammonia-lyase activity [PMID:7042346]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0042645 mitochondrial nucleoid [PMID:15692048]
experiment: EXISTENCE:genetic interaction:GO:0006565 L-serine catabolic process [PMID:7042346]
experiment: EXISTENCE:genetic interaction:GO:0006567 threonine catabolic process [PMID:7042346]
note: Catabolic L-serine (L-threonine) deaminase; catalyzes the degradation of both L-serine and L-threonine; required to use serine or threonine as the sole nitrogen source, transcriptionally induced by serine and threonine
codon start: 1
product: L-serine/L-threonine ammonia-lyase CHA1
translation: MSIVYNKTPLLRQFFPGKASAQFFLKYECLQPSGSFKSRGIGNLIMKSAIRIQKDGKRSPQVFASSGGNAGFAAATACQRLSLPCTVVVPTATKKRMVDKIRNTGAQVIVSGAYWKEADTFLKTNVMNKIDSQVIEPIYVHPFDNPDIWEGHSSMIDEIVQDLKSQHISVNKVKGIVCSVGGGGLYNGIIQGLERYGLADRIPIVGVETNGCHVFNTSLKIGQPVQFKKITSIATSLGTAVISNQTFEYARKYNTRSVVIEDKDVIETCLKYTHQFNMVIEPACGAALHLGYNTKILENALGSKLAADDIVIIIACGGSSNTIKDLEEALDSMRKKDTPVIEVADNFIFPEKNIVNLKSA
SIO_010081: YCL064C
subclass of: SO_0000673
so part of: YCL064C
location: complement(15798..16880)
location: region:15798-16880:-1
so has part: feature:15798-16880:-1:exon

NP_001018030.1
type: Protein
SIO_000068: ncbiprotein

S000000569
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:15798-16880:-1:exon

YCL063W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YCL062W
gene: VAC17
locus tag: YCL063W
gene synonym: YCL062W
so part of: sequence
location: <17290..>18561
location: region:17290-18561:1
so has part: feature:17290-18561:1:exon
subclass of: SO_0000010

850296
type: Gene
SIO_000068: ncbigene

position:17290:1
position: 17290
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:18561:1
position: 18561
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:17290-18561:1:exon

YCL063W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YCL062W
gene: VAC17
locus tag: YCL063W
gene synonym: YCL062W
product: Vac17p
transcript id: NM_001178705.1
SIO_010081: YCL063W
subclass of: SO_0000673
so part of: YCL063W
location: <17290..>18561
location: region:17290-18561:1
so has part: feature:17290-18561:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:17290-18561:1:exon

YCL063W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YCL062W
gene: VAC17
locus tag: YCL063W
gene synonym: YCL062W
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:12594460]
experiment: EXISTENCE:genetic interaction:GO:0000011 vacuole inheritance [PMID:12594460]
experiment: EXISTENCE:mutant phenotype:GO:0000011 vacuole inheritance [PMID:12594460]
experiment: EXISTENCE:physical interaction:GO:0000011 vacuole inheritance [PMID:12594460]
experiment: EXISTENCE:physical interaction:GO:0043495 protein-membrane adaptor activity [PMID:12642614]
experiment: EXISTENCE:physical interaction:GO:0071563 Myo2p-Vac17p-Vac8p transport complex [PMID:12594460]
note: Phosphoprotein involved in vacuole inheritance; degraded in late M phase of the cell cycle; acts as a vacuole-specific receptor for myosin Myo2p; involved in regulation of asymmetric inheritance of aggregated/misfolded proteins and age reset
codon start: 1
product: Vac17p
translation: MATQALEDITERLLIRSQEAILQLDLWIQRQQRSSICQTTDQESLDKLSQQYNQYMSQLNSLYVRSESVRDKLSKEQQRRLITEDNEHQRIEDLVREFQDITLRLNELATVPNEAPNDSPQSQSTRSSLGSFQPRPLKIIERQRLCMVTPSKPPKKSVGFNPINEVDCPSKTNSLPCSPKKQPARNRTLRAAKSHDTGLNKSKKPSSSDTYESFFKNRQRLSLTFFDEMDDEDFDSDQDTIILPNISTPPHVGVTAKGAEFEPLRRYNSHESILSNKPAPSKSLNLGSFSASFFRPSNPTFGTSISNVQVNCHPTVAATMAPSRNGPRISSSKALLSSFIARSDTHTVKENNTNLKHASFMDKFNSSLSTISESFQSKRGRKNKGMNEERISNHNVAQEQKNNMDISVSIEELQDALNTELLF
SIO_010081: YCL063W
subclass of: SO_0000673
so part of: YCL063W
location: 17290..18561
location: region:17290-18561:1
so has part: feature:17290-18561:1:exon

NP_009870.1
type: Protein
SIO_000068: ncbiprotein

S000000568
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:17290-18561:1:exon

YCL061C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YCL060C
gene: MRC1
locus tag: YCL061C
gene synonym: YCL060C
so part of: sequence
location: complement(<18816..>22106)
location: region:18816-22106:-1
so has part: feature:18816-22106:-1:exon
subclass of: SO_0000010

850297
type: Gene
SIO_000068: ncbigene

position:18816:-1
position: 18816
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:22106:-1
position: 22106
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:18816-22106:-1:exon

YCL061C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YCL060C
gene: MRC1
locus tag: YCL061C
gene synonym: YCL060C
product: chromatin-modulating protein MRC1
transcript id: NM_001178704.1
SIO_010081: YCL061C
subclass of: SO_0000673
so part of: YCL061C
location: complement(<18816..>22106)
location: region:18816-22106:-1
so has part: feature:18816-22106:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:18816-22106:-1:exon

YCL061C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YCL060C
gene: MRC1
locus tag: YCL061C
gene synonym: YCL060C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0031298 replication fork protection complex [PMID:16531994]
experiment: EXISTENCE:direct assay:GO:0034399 nuclear periphery [PMID:25817432]
experiment: EXISTENCE:direct assay:GO:0043596 nuclear replication fork [PMID:16103218]
experiment: EXISTENCE:genetic interaction:GO:0006281 DNA repair [PMID:16219777]
experiment: EXISTENCE:genetic interaction:GO:0007064 mitotic sister chromatid cohesion [PMID:17483413]
experiment: EXISTENCE:genetic interaction:GO:0048478 replication fork protection [PMID:18851837]
experiment: EXISTENCE:mutant phenotype:GO:0000076 DNA replication checkpoint signaling [PMID:11331602|PMID:11715016|PMID:12944972]
experiment: EXISTENCE:mutant phenotype:GO:0000723 telomere maintenance [PMID:17323081]
experiment: EXISTENCE:mutant phenotype:GO:0006260 DNA replication [PMID:16137625]
experiment: EXISTENCE:mutant phenotype:GO:0006281 DNA repair [PMID:16219777]
experiment: EXISTENCE:mutant phenotype:GO:0007064 mitotic sister chromatid cohesion [PMID:17483413]
experiment: EXISTENCE:mutant phenotype:GO:0030466 silent mating-type cassette heterochromatin formation [PMID:11331602]
experiment: EXISTENCE:mutant phenotype:GO:0031509 subtelomeric heterochromatin formation [PMID:11331602]
experiment: EXISTENCE:mutant phenotype:GO:0031573 mitotic intra-S DNA damage checkpoint signaling [PMID:11715016]
experiment: EXISTENCE:mutant phenotype:GO:0033262 regulation of nuclear cell cycle DNA replication [PMID:23178807]
experiment: EXISTENCE:mutant phenotype:GO:0043570 maintenance of DNA repeat elements [PMID:18321795]
experiment: EXISTENCE:mutant phenotype:GO:0048478 replication fork protection [PMID:18632578]
experiment: EXISTENCE:physical interaction:GO:0048478 replication fork protection [PMID:18851837]
note: S-phase checkpoint protein required for DNA replication; couples DNA helicase and polymerase; stabilizes Pol2p at stalled replication forks during stress, where it forms a pausing complex with Tof1p and is phosphorylated by Mec1p; defines a novel S-phase checkpoint with Hog1p that coordinates DNA replication and transcription upon osmostress; protects uncapped telomeres; Dia2p-dependent degradation mediates checkpoint recovery; exposure to ethanol affects localization; mammalian claspin homolog
codon start: 1
product: chromatin-modulating protein MRC1
translation: MDDALHALSSLTAKKRTTTYKKVAVPILDENDNTNGNGPNDIDNPPELTGNGFLFANATLNRVKNRLEGKKAPEQNHNNGKDRSENSLPTQLISNLYDGGEELEKSEVKDNSYSEKNVSSSFTQTQRIPVSIQQDKVFNVPIHSVNDGKPTQLIKEDGLVNETSQALKTPLTTGRPGATQRIDSSGATSQTQPIKSIEPQSQIITTSSNHSNALSPKIPIIPTELIGTSPLFQSIQNRGPDTQMDVPPQTAHDEDKTQAIGIPQATHQEQKTQIDTVAQTLQDEVPHTLKIREIQSELASEDSKREKARNVEYKKPQKPIPTKKFFSKESFLADFDDSSSNEDDDIKLENAHPKPVQNDDELHENKSVELNLTDETRINEKRVPLLSSYANNLKREIDSSKCITLDLDSDSDEYGDDDMDSIKLSKDESVLPISQLSKATILNLKARLSKQNQKLSQRPNKSKDPKVDHNVLLNTLRKASRKQILDHQKEVIETKGLKLEDMAKEKEIVENLLEQEILRNKRIRQKEKRREKLEENDFQLNAHDSGSDSGSESSGFALSGNEIADYESSGSENDNRRESDSEKEDDEIILKQKKSHHVKHIINESDSDTEVEAKPKEKADESLPKRIAINLGHYGDNIGEDTDKFQETNVLDTQNIEEVMAERNTIENEVKDDVYVNEEADEAIRRQLIDKEKLQLKQKEKEHEAKIKELKKRGVTNFFEMEAEESEDEWHGIGGADGEGSDDYDSDLEKMIDDYSKNNFNPHEIREMLAAENKEMDIKMINKILYDIKNGGFRNKRAKNSLELELSDDDEDDVLQQYRLKRRELMRKRRLEIGDDAKLVKNPKSSAFFESMVEDIIEYKNPFGAEEEYNLDITSTATDLDTQDNSINVGDNTGNNEQKPVDQKNKKVIISEDFVQKSLSFLKSNNYEDFETDKELSRIQHGNDEAIEDLYTLKQNSSIKSFTNSQTDSTTSKTVNTIIDLEKRPEDEDEVENGDTSLVGVFKHPSIIKSFASRTDINDKFKEGNKTVKILKSYKTVGSSKASITYMGKTRKLIAPKRKTEGSHRYHHDHHNKKMKMKTKTKSNKLFESGQDSFDN
SIO_010081: YCL061C
subclass of: SO_0000673
so part of: YCL061C
location: complement(18816..22106)
location: region:18816-22106:-1
so has part: feature:18816-22106:-1:exon

NP_009871.2
type: Protein
SIO_000068: ncbiprotein

S000000566
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:18816-22106:-1:exon

YCL059C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: KRR1
locus tag: YCL059C
so part of: sequence
location: complement(<22429..>23379)
location: region:22429-23379:-1
so has part: feature:22429-23379:-1:exon
subclass of: SO_0000010

850298
type: Gene
SIO_000068: ncbigene

position:22429:-1
position: 22429
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:23379:-1
position: 23379
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:22429-23379:-1:exon

YCL059C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: KRR1
locus tag: YCL059C
product: ribosome biosynthesis protein KRR1
transcript id: NM_001178703.1
SIO_010081: YCL059C
subclass of: SO_0000673
so part of: YCL059C
location: complement(<22429..>23379)
location: region:22429-23379:-1
so has part: feature:22429-23379:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:22429-23379:-1:exon

YCL059C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: KRR1
locus tag: YCL059C
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:11027267|PMID:12150911]
experiment: EXISTENCE:direct assay:GO:0030686 90S preribosome [PMID:12150911]
experiment: EXISTENCE:direct assay:GO:0030688 preribosome, small subunit precursor [PMID:15167894]
experiment: EXISTENCE:direct assay:GO:0032040 small-subunit processome [PMID:15590835]
experiment: EXISTENCE:mutant phenotype:GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:11027267]
experiment: EXISTENCE:mutant phenotype:GO:0006364 rRNA processing [PMID:11996121]
experiment: EXISTENCE:mutant phenotype:GO:0042274 ribosomal small subunit biogenesis [PMID:12150911]
note: Nucleolar protein required for rRNA synthesis and ribosomal assembly; required for the synthesis of 18S rRNA and for the assembly of 40S ribosomal subunit; essential gene
codon start: 1
product: ribosome biosynthesis protein KRR1
translation: MVSTHNRDKPWDTDDIDKWKIEEFKEEDNASGQPFAEESSFMTLFPKYRESYLKTIWNDVTRALDKHNIACVLDLVEGSMTVKTTRKTYDPAIILKARDLIKLLARSVPFPQAVKILQDDMACDVIKIGNFVTNKERFVKRRQRLVGPNGNTLKALELLTKCYILVQGNTVSAMGPFKGLKEVRRVVEDCMKNIHPIYHIKELMIKRELAKRPELANEDWSRFLPMFKKRNVARKKPKKIRNVEKKVYTPFPPAQLPRKVDLEIESGEYFLSKREKQMKKLNEQKEKQMEREIERQEERAKDFIAPEEEAYKPNQN
SIO_010081: YCL059C
subclass of: SO_0000673
so part of: YCL059C
location: complement(22429..23379)
location: region:22429-23379:-1
so has part: feature:22429-23379:-1:exon

NP_009872.1
type: Protein
SIO_000068: ncbiprotein

S000000564
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:22429-23379:-1:exon

YCL058C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MDF1
gene: FYV5
locus tag: YCL058C
gene synonym: MDF1
so part of: sequence
location: complement(<23523..>23981)
location: region:23523-23981:-1
so has part: feature:23523-23981:-1:exon
subclass of: SO_0000010

850299
type: Gene
SIO_000068: ncbigene

position:23523:-1
position: 23523
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:23981:-1
position: 23981
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:23523-23981:-1:exon

YCL058C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MDF1
gene: FYV5
locus tag: YCL058C
gene synonym: MDF1
product: Fyv5p
transcript id: NM_001178702.1
SIO_010081: YCL058C
subclass of: SO_0000673
so part of: YCL058C
location: complement(<23523..>23981)
location: region:23523-23981:-1
so has part: feature:23523-23981:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:23523-23981:-1:exon

YCL058C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MDF1
gene: FYV5
locus tag: YCL058C
gene synonym: MDF1
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:26649943]
experiment: EXISTENCE:mutant phenotype:GO:0000750 pheromone-dependent signal transduction involved in conjugation with cellular fusion [PMID:20195295]
experiment: EXISTENCE:mutant phenotype:GO:0006873 cellular ion homeostasis [PMID:10234789]
note: De novo-originated gene from non-coding sequence; protein can suppress mating and promote vegetative growth; shortens lag phase by physically interacting with Snf1p; binds with Matalpha2p to promoters of haploid-specific genes; functions in mating and fermentation, mediates crosstalk between reproduction and vegetative growth; required for survival upon exposure to K1 killer toxin; involved in ion homeostasis
codon start: 1
product: Fyv5p
translation: MQYHSALYVYIYVTFTTIPYKEKPDIISICFSMLSFVFDFSVRICSRTLESFSWSLISSSAFKVVSAFSLAGSCVLASRSSVGIIVSLLLFNFSTCNFVLFLSAVLIDLFFCTFLPTPTFLPTPFFFMLHLPIFSLLNALELLYLIIAGLHI
SIO_010081: YCL058C
subclass of: SO_0000673
so part of: YCL058C
location: complement(23523..23981)
location: region:23523-23981:-1
so has part: feature:23523-23981:-1:exon

NP_009873.1
type: Protein
SIO_000068: ncbiprotein

S000000563
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:23523-23981:-1:exon

YCL058W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ADF1
locus tag: YCL058W-A
so part of: sequence
location: <23584..>23925
location: region:23584-23925:1
so has part: feature:23584-23925:1:exon
subclass of: SO_0000010

3289591
type: Gene
SIO_000068: ncbigene

position:23584:1
position: 23584
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:23925:1
position: 23925
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:23584-23925:1:exon

YCL058W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ADF1
locus tag: YCL058W-A
product: Adf1p
transcript id: NM_001184528.1
SIO_010081: YCL058W-A
subclass of: SO_0000673
so part of: YCL058W-A
location: <23584..>23925
location: region:23584-23925:1
so has part: feature:23584-23925:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:23584-23925:1:exon

YCL058W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ADF1
locus tag: YCL058W-A
experiment: EXISTENCE:direct assay:GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding [PMID:20195295]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:20195295]
experiment: EXISTENCE:mutant phenotype:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:20195295]
experiment: EXISTENCE:mutant phenotype:GO:0000750 pheromone-dependent signal transduction involved in conjugation with cellular fusion [PMID:20195295]
note: Transcriptional repressor encoded by the FYV5 antisense strand; negatively regulates transcription of FYV5 by binding to the promoter on the sense strand
codon start: 1
product: Adf1p
translation: MGKCSMKKKGVGKNVGVGKKVQKKRSISTAERKRTKLQVEKLNKSSETMIPTLLREASTQEPAKLKAETTLKAEELIKDQEKDSKVREQIRTEKSKTNDSMLKQIEMISGFSL
SIO_010081: YCL058W-A
subclass of: SO_0000673
so part of: YCL058W-A
location: 23584..23925
location: region:23584-23925:1
so has part: feature:23584-23925:1:exon

NP_001018031.2
type: Protein
SIO_000068: ncbiprotein

S000028518
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:23584-23925:1:exon

YCL057C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MCS10
alternative label: MIO10
alternative label: MOS1
gene: MIC10
locus tag: YCL057C-A
gene synonym: MCS10; MIO10; MOS1
so part of: sequence
location: complement(<24032..>24325)
location: region:24032-24325:-1
so has part: feature:24032-24325:-1:exon
subclass of: SO_0000010

850300
type: Gene
SIO_000068: ncbigene

position:24032:-1
position: 24032
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:24325:-1
position: 24325
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:24032-24325:-1:exon

YCL057C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MCS10
alternative label: MIO10
alternative label: MOS1
gene: MIC10
locus tag: YCL057C-A
gene synonym: MCS10; MIO10; MOS1
product: Mic10p
transcript id: NM_001184448.1
SIO_010081: YCL057C-A
subclass of: SO_0000673
so part of: YCL057C-A
location: complement(<24032..>24325)
location: region:24032-24325:-1
so has part: feature:24032-24325:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:24032-24325:-1:exon

YCL057C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MCS10
alternative label: MIO10
alternative label: MOS1
gene: MIC10
locus tag: YCL057C-A
gene synonym: MCS10; MIO10; MOS1
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0044284 mitochondrial crista junction [PMID:22009199]
experiment: EXISTENCE:direct assay:GO:0061024 membrane organization [PMID:25955211]
experiment: EXISTENCE:direct assay:GO:0061617 MICOS complex [PMID:21944719|PMID:21987634|PMID:22009199]
experiment: EXISTENCE:mutant phenotype:GO:0042407 cristae formation [PMID:21944719|PMID:21987634|PMID:22009199]
note: Conserved component of the MICOS complex; MICOS (formerly MINOS or MitOS) is a mitochondrial inner membrane complex that extends into the intermembrane space and has a role in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane; forms a subcomplex with Mic12p and Mic27p whose assembly and stability requires cardiolipin; homo-oligomers cause membrane bending; ortholog of human MINOS1
codon start: 1
product: Mic10p
translation: MSEQAQTQQPAKSTPSKDSNKNGSSVSTILDTKWDIVLSNMLVKTAMGFGVGVFTSVLFFKRRAFPVWLGIGFGVGRGYAEGDAIFRSSAGLRSSKV
SIO_010081: YCL057C-A
subclass of: SO_0000673
so part of: YCL057C-A
location: complement(24032..24325)
location: region:24032-24325:-1
so has part: feature:24032-24325:-1:exon

NP_065435.1
type: Protein
SIO_000068: ncbiprotein

S000007547
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:24032-24325:-1:exon

YCL057W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PRD1
locus tag: YCL057W
so part of: sequence
location: <24768..>26906
location: region:24768-26906:1
so has part: feature:24768-26906:1:exon
subclass of: SO_0000010

850301
type: Gene
SIO_000068: ncbigene

position:24768:1
position: 24768
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:26906:1
position: 26906
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:24768-26906:1:exon

YCL057W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PRD1
locus tag: YCL057W
product: metalloendopeptidase
transcript id: NM_001178701.1
SIO_010081: YCL057W
subclass of: SO_0000673
so part of: YCL057W
location: <24768..>26906
location: region:24768-26906:1
so has part: feature:24768-26906:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:24768-26906:1:exon

YCL057W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PRD1
locus tag: YCL057W
EC number: 3.4.24.37
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:8218194]
experiment: EXISTENCE:direct assay:GO:0004222 metalloendopeptidase activity [PMID:8218194|PMID:8307027]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:8307027|PMID:14562095|PMID:24390141]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:24769239|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005758 mitochondrial intermembrane space [PMID:8307027]
experiment: EXISTENCE:direct assay:GO:0005794 Golgi apparatus [PMID:8218194]
experiment: EXISTENCE:direct assay:GO:0006508 proteolysis [PMID:8307027]
experiment: EXISTENCE:mutant phenotype:GO:0004222 metalloendopeptidase activity [PMID:8307027]
experiment: EXISTENCE:mutant phenotype:GO:0006508 proteolysis [PMID:8307027]
note: Zinc metalloendopeptidase; found in the cytoplasm and intermembrane space of mitochondria; with Cym1p, involved in degradation of mitochondrial proteins and of presequence peptides cleaved from imported proteins; protein abundance increases in response to DNA replication stress
codon start: 1
product: metalloendopeptidase
translation: MRLLLCKNWFASPVISPLLYTRSLYSMANTTSFPIAPQAPPNWSFTPSDISGKTNEIINNSNNFYDSMSKVESPSVSNFVEPFMKFENELGPIINQLTFLQHVSSDKEIRDASVNSSMKLDELNIDLSLRHDIFLQFARVWQDVQSKADSVERETFKYVEKSYKDYIHSGLELDEGNRLKIKEIKKKISVNSINFSKNLGEQKEYITFTKEQLEGVPDSILTQFETIKSDKDSNETLYKVTFKYPDIFPVMKLASSAQTRKQAFLADQNKVPENEAILLDTLKLRDELASLLGYDTYANYNLYDKMAEDSTTVMNFLNDLKDKLIPLGRKELQVLQDMKAEDVKKLNQGADPNYYIWDHRYYDNKYLLENFNVDLEKISEYFPLEATITGMLEIYETLFNLKFIETKDSQNKSVWHDDVKQIAVWNMDDPKSPNFVGWIYFDLHPRDGKYGHAANFGLSSSFMIDDTTRSYPVTALVCNFSKSTKDKPSLLKHNEIVTFFHELGHGIHDLVGQNKESRFNGPGSVPWDFVEAPSQMLEFWTWNKNELINLSSHYKTGEKIPESLINSLIKTKHVNGALFTLRQLHFGLFDMKVHTCKDLQNLSICDTWNQLRQDISLISNGGTLSKGYDSFGHIMSDSYSAGYYGYLWAEVFATDMYHTKFAKDPLNAKNGIQYRDIVLARGGLYDINDNLKEFLGREPSKDAFLKELGLQN
SIO_010081: YCL057W
subclass of: SO_0000673
so part of: YCL057W
location: 24768..26906
location: region:24768-26906:1
so has part: feature:24768-26906:1:exon

NP_009874.1
type: Protein
SIO_000068: ncbiprotein

S000000562
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:24768-26906:1:exon

YCL056C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PEX34
locus tag: YCL056C
so part of: sequence
location: complement(<26925..>27359)
location: region:26925-27359:-1
so has part: feature:26925-27359:-1:exon
subclass of: SO_0000010

850302
type: Gene
SIO_000068: ncbigene

position:26925:-1
position: 26925
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:27359:-1
position: 27359
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:26925-27359:-1:exon

YCL056C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PEX34
locus tag: YCL056C
product: Pex34p
transcript id: NM_001178700.1
SIO_010081: YCL056C
subclass of: SO_0000673
so part of: YCL056C
location: complement(<26925..>27359)
location: region:26925-27359:-1
so has part: feature:26925-27359:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:26925-27359:-1:exon

YCL056C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PEX34
locus tag: YCL056C
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005778 peroxisomal membrane [PMID:21441307]
experiment: EXISTENCE:genetic interaction:GO:0007031 peroxisome organization [PMID:21441307]
experiment: EXISTENCE:mutant phenotype:GO:0007031 peroxisome organization [PMID:21441307]
note: Protein that regulates peroxisome populations; peroxisomal integral membrane protein; interacts with Pex11p, Pex25p, and Pex27p to control both constitutive peroxisome division and peroxisome morphology and abundance during peroxisome proliferation
codon start: 1
product: Pex34p
translation: MVSKKNTAEISAKDIWENIWSGVSSLLDFFAVLENLGVVNDKLYVSGLLRKVWLCYSCISVIKCVWKLIKLCKVKFKIDQRLDGEGNGLVKDKLINFKKKYNEHIRHITAALLQDLSYLMVLIYPGTRLFKRLSNIITLCRIIV
SIO_010081: YCL056C
subclass of: SO_0000673
so part of: YCL056C
location: complement(26925..27359)
location: region:26925-27359:-1
so has part: feature:26925-27359:-1:exon

NP_009875.1
type: Protein
SIO_000068: ncbiprotein

S000000561
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:26925-27359:-1:exon

YCL055W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: KAR4
locus tag: YCL055W
so part of: sequence
location: <27929..>28936
location: region:27929-28936:1
so has part: feature:27929-28936:1:exon
subclass of: SO_0000010

850303
type: Gene
SIO_000068: ncbigene

position:27929:1
position: 27929
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:28936:1
position: 28936
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:27929-28936:1:exon

YCL055W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: KAR4
locus tag: YCL055W
product: Kar4p
transcript id: NM_001178699.1
SIO_010081: YCL055W
subclass of: SO_0000673
so part of: YCL055W
location: <27929..>28936
location: region:27929-28936:1
so has part: feature:27929-28936:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:27929-28936:1:exon

YCL055W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: KAR4
locus tag: YCL055W
experiment: EXISTENCE:direct assay:GO:0003700 DNA-binding transcription factor activity [PMID:17101777]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0003700 DNA-binding transcription factor activity [PMID:17101777]
experiment: EXISTENCE:mutant phenotype:GO:0000742 karyogamy involved in conjugation with cellular fusion [PMID:8754797]
experiment: EXISTENCE:mutant phenotype:GO:0003700 DNA-binding transcription factor activity [PMID:17101777]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:17101777]
experiment: EXISTENCE:mutant phenotype:GO:0051321 meiotic cell cycle [PMID:8754797]
note: Transcription factor required for response to pheromones; also required during meiosis; exists in two forms, a slower-migrating form more abundant during vegetative growth and a faster-migrating form induced by pheromone; null mutant exhibits abnormal lipid metabolic phenotype
codon start: 1
product: Kar4p
translation: MAFQDPTYDQNKSRHINNSHLQGPNQETIEMKSKHVSFKPSRDFHTNDYSNNYIHGKSLPQQHVTNIENRVDGYPKLQKLFQAKAKQINQFATTPFGCKIGIDSIVPTLNHWIQNENLTFDVVMIGCLTENQFIYPILTQLPLDRLISKPGFLFIWANSQKINELTKLLNNEIWAKKFRRSEELVFVPIDKKSPFYPGLDQDDETLMEKMQWHCWMCITGTVRRSTDGHLIHCNVDTDLSIETKDTTNGAVPSHLYRIAENFSTATRRLHIIPARTGYETPVKVRPGWVIVSPDVMLDNFSPKRYKEEIANLGSNIPLKNEIELLRPRSPVQKAQ
SIO_010081: YCL055W
subclass of: SO_0000673
so part of: YCL055W
location: 27929..28936
location: region:27929-28936:1
so has part: feature:27929-28936:1:exon

NP_009876.1
type: Protein
SIO_000068: ncbiprotein

S000000560
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:27929-28936:1:exon

regulatory
type: Feature
subclass of: SO_0000001
RO_0002162: 559292
regulatory class: other
note: RE (recombination enhancer); Orientation-independent recombination enhancer; cis-acting region that controls mating-type dependent recombination along entire left arm of Chromosome III; Sir2p and the condensin complex are recruited to the RE exclusively in MATa cells, where the RE drives donor preference directional switching; RDT1 expression is MATa-specific
so part of: sequence
location: 29108..29809
location: region:29108-29809:1
so has part: feature:29108-29809:1:region

S000303804
type: SGD
SIO_000068: sgd

position:29108:1
position: 29108
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:29809:1
position: 29809
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:29108-29809:1:region

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS304; Autonomously Replicating Sequence on Chromosome III
so part of: sequence
location: 30200..30657
location: region:30200-30657:1
so has part: feature:30200-30657:1:region

S000028481
type: SGD
SIO_000068: sgd

position:30200:1
position: 30200
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:30657:1
position: 30657
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:30200-30657:1:region

YCL054W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RDT1
locus tag: YCL054W-A
so part of: sequence
location: <30910..>30996
location: region:30910-30996:1
so has part: feature:30910-30996:1:exon
subclass of: SO_0000010

23547378
type: Gene
SIO_000068: ncbigene

position:30910:1
position: 30910
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:30996:1
position: 30996
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:30910-30996:1:exon

YCL054W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RDT1
locus tag: YCL054W-A
product: Rdt1p
transcript id: NM_001305014.1
SIO_010081: YCL054W-A
subclass of: SO_0000673
so part of: YCL054W-A
location: <30910..>30996
location: region:30910-30996:1
so has part: feature:30910-30996:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:30910-30996:1:exon

YCL054W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RDT1
locus tag: YCL054W-A
note: Small gene in chromosome III recombination enhancer; activated during mating-type switching; bound by condensin complex, deletion drastically changes chromosome III structure, alters donor preference; promoter functions as locus control region (LCR) that regulates both transcription and long-range chromatin interactions
codon start: 1
product: Rdt1p
translation: MIRQKIFVFIVKSRRNSICPAIRRKEDY
SIO_010081: YCL054W-A
subclass of: SO_0000673
so part of: YCL054W-A
location: 30910..30996
location: region:30910-30996:1
so has part: feature:30910-30996:1:exon

NP_001291943.1
type: Protein
SIO_000068: ncbiprotein

S000178054
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:30910-30996:1:exon

YCL054W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SPB1
locus tag: YCL054W
so part of: sequence
location: <31449..>33974
location: region:31449-33974:1
so has part: feature:31449-33974:1:exon
subclass of: SO_0000010

850304
type: Gene
SIO_000068: ncbigene

position:31449:1
position: 31449
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:33974:1
position: 33974
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:31449-33974:1:exon

YCL054W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SPB1
locus tag: YCL054W
product: 27S pre-rRNA (guanosine2922-2'-O)-methyltransferase
transcript id: NM_001178698.1
SIO_010081: YCL054W
subclass of: SO_0000673
so part of: YCL054W
location: <31449..>33974
location: region:31449-33974:1
so has part: feature:31449-33974:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:31449-33974:1:exon

YCL054W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SPB1
locus tag: YCL054W
EC number: 2.1.1.167
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:10556316]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:10556316|PMID:10648622]
experiment: EXISTENCE:direct assay:GO:0030687 preribosome, large subunit precursor [PMID:11583614]
experiment: EXISTENCE:direct assay:GO:0031167 rRNA methylation [PMID:15546625]
experiment: EXISTENCE:genetic interaction:GO:0008650 rRNA (uridine-2'-O-)-methyltransferase activity [PMID:14636587]
experiment: EXISTENCE:genetic interaction:GO:0031167 rRNA methylation [PMID:14636587|PMID:15546625]
experiment: EXISTENCE:mutant phenotype:GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:10556316|PMID:10648622]
experiment: EXISTENCE:mutant phenotype:GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:10556316|PMID:10648622]
experiment: EXISTENCE:mutant phenotype:GO:0016435 rRNA (guanine) methyltransferase activity [PMID:15546625]
experiment: EXISTENCE:mutant phenotype:GO:0031167 rRNA methylation [PMID:15546625]
note: AdoMet-dependent methyltransferase; involved in rRNA processing and 60S ribosomal subunit maturation; methylates G2922 in the tRNA docking site of the large subunit rRNA and in the absence of snR52, U2921; suppressor of PAB1 mutants
codon start: 1
product: 27S pre-rRNA (guanosine2922-2'-O)-methyltransferase
translation: MGKTQKKNSKGRLDRYYYLAKEKGYRARSSFKIIQINEKYGHFLEKSKVVIDLCAAPGSWCQVASKLCPVNSLIIGVDIVPMKPMPNVITFQSDITTEDCRSKLRGYMKTWKADTVLHDGAPNVGLGWVQDAFTQSQLTLQALKLAVENLVVNGTFVTKIFRSKDYNKLIWVFQQLFEKVEATKPPASRNVSAEIFVVCKGFKAPKRLDPRLLDPKEVFEELPDGQQNMESKIYNPEKKVRKRQGYEEGDNLLYHETSILDFVRTEDPISMLGEMNKFTIDENDHEWKILKKLKQTTDEFRSCIEDLKVLGKKDFKMILRWRKIAREILGIEVKDDAKTEIEVVPLTEEEQIEKDLQGLQEKQRLNVKRERRRKNEMKQKELQRMQMNMITPTDIGIEAASLGKESLFNLKTAEKTGILNDLAKGKKRMIFTDDELAKDNDIYIDENIMIKDKDSAADADDLESELNAMYSDYKTRRSERDAKFRAKQARGGDNEEEWTGFNEGSLEKKEEEGKDYIEDNDDEGVEGDSDDDEAITNLISKLKGQEGDHKLSSKARMIFNDPIFNNVEPDLPVNTVNDGIMSSESVGDISKLNKKRKHEEMHQKQDEADSSDESSSDDSDFEIVANDNASEEFDSDYDSEEEKNQTKKEKHSRDIDIATVEAMTLAHQLALGQKNKHDLVDEGFNRYTFRDTENLPDWFLEDEKEHSKINKPITKEAAMAIKEKIKAMNARPIKKVAEAKARKRMRAVARLEKIKKKAGLINDDSDKTEKDKAEEISRLMRKVTKKPKTKPKVTLVVASGRNKGLAGRPKGVKGKYKMVDGVMKNEQRALRRIAKKHHKKK
SIO_010081: YCL054W
subclass of: SO_0000673
so part of: YCL054W
location: 31449..33974
location: region:31449-33974:1
so has part: feature:31449-33974:1:exon

NP_009877.1
type: Protein
SIO_000068: ncbiprotein

S000000559
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:31449-33974:1:exon

YCL052C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PBN1
locus tag: YCL052C
so part of: sequence
location: complement(<34143..>35393)
location: region:34143-35393:-1
so has part: feature:34143-35393:-1:exon
subclass of: SO_0000010

850305
type: Gene
SIO_000068: ncbigene

position:34143:-1
position: 34143
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:35393:-1
position: 35393
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:34143-35393:-1:exon

YCL052C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PBN1
locus tag: YCL052C
product: Pbn1p
transcript id: NM_001178697.1
SIO_010081: YCL052C
subclass of: SO_0000673
so part of: YCL052C
location: complement(<34143..>35393)
location: region:34143-35393:-1
so has part: feature:34143-35393:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:34143-35393:-1:exon

YCL052C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PBN1
locus tag: YCL052C
experiment: EXISTENCE:direct assay:GO:0000030 mannosyltransferase activity [PMID:15635094]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:9649520|PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0006506 GPI anchor biosynthetic process [PMID:15635094]
experiment: EXISTENCE:mutant phenotype:GO:0016485 protein processing [PMID:9649520]
experiment: EXISTENCE:mutant phenotype:GO:0030433 ubiquitin-dependent ERAD pathway [PMID:16418276]
experiment: EXISTENCE:physical interaction:GO:1990529 glycosylphosphatidylinositol-mannosyltransferase I complex [PMID:15635094]
note: Component of glycosylphosphatidylinositol-mannosyltransferase I; essential component; required for the autocatalytic post-translational processing of the protease B precursor Prb1p; localizes to ER in lumenal orientation; homolog of mammalian PIG-X
codon start: 1
product: Pbn1p
translation: MVTRHRVTVLYNAPEDIGNHMRQNDTHLTVRGGSGVVLQQRWLLERTGSLDKSFTRITWRPRADLARSLSVIENELSAGFSVYSNSSDVPERFITNPVYNSFHSEKFDIEQYLPPEVDLNLSWNPEDFTYDISVEPTQIQIVEYRLLKQGEEFTIARVKDEKLEVGVFFVDASDESDVDIGGIRCNWRMDDGKMERCQKTSLLYKQGHIAYNHSTTTTSLYLNEPIGLHPKIMIDLTDFEERPKCMYLMHLQLPLELFIDKFQSSPLLLFGEDDLELPEYSLRDKAWGSESIFELKAGTMNEVTLHTRYIEPSNNKGDKLEVSFDPEVILACDTGDNKVSRNPFYKKGLGYESLFTDDTTFRHLNSTTLLVPIPRPDTKDYSKIKNGTLLCLLISIIYIFSKVFGNNKKKRSVKRE
SIO_010081: YCL052C
subclass of: SO_0000673
so part of: YCL052C
location: complement(34143..35393)
location: region:34143-35393:-1
so has part: feature:34143-35393:-1:exon

NP_009878.1
type: Protein
SIO_000068: ncbiprotein

S000000557
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:34143-35393:-1:exon

YCL051W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: LRE1
locus tag: YCL051W
so part of: sequence
location: <35865..>37616
location: region:35865-37616:1
so has part: feature:35865-37616:1:exon
subclass of: SO_0000010

850306
type: Gene
SIO_000068: ncbigene

position:35865:1
position: 35865
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:37616:1
position: 37616
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:35865-37616:1:exon

YCL051W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: LRE1
locus tag: YCL051W
product: Lre1p
transcript id: NM_001178696.1
SIO_010081: YCL051W
subclass of: SO_0000673
so part of: YCL051W
location: <35865..>37616
location: region:35865-37616:1
so has part: feature:35865-37616:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:35865-37616:1:exon

YCL051W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: LRE1
locus tag: YCL051W
experiment: EXISTENCE:direct assay:GO:0004860 protein kinase inhibitor activity [PMID:23954433]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:23954433]
experiment: EXISTENCE:direct assay:GO:0006469 negative regulation of protein kinase activity [PMID:23954433]
experiment: EXISTENCE:genetic interaction:GO:0031505 fungal-type cell wall organization [PMID:11532139]
experiment: EXISTENCE:mutant phenotype:GO:0031505 fungal-type cell wall organization [PMID:9090049]
note: Protein involved in control of cell wall structure and stress response; direct inhibitor of the nuclear Dbf2 related (NDR) kinase Cbk1p-Mob2p; overproduction confers resistance to cell-wall degrading enzymes; exhibits genetic interactions with genes involved in the cell wall integrity pathway; LRE1 has a paralog, HLR1, that arose from the whole genome duplication
codon start: 1
product: Lre1p
translation: MPNTHTQHVQISEPNPVNTLSTPSKRGHRHRRSLAISGDFDFLKQPAAIVNLPPPQAAENCPSTAPTAVSSTLSPIRYNRFPCKTNEDAGTLDLPEPRFYPLSPKNNLQTPSPRFFISEEPSFSSPVKGVPDAIINLDDALKTRPRSFKSHRRSESAPPDLEVMVDKGNCAAGSNSMIKEEEDSLIEPESKNEYYEQKLPTALLSPLRPSLCVSEQAIDVDDSALNGSPTHHNHGMQNANARNSNTFNSLKIKGQKQRYYHYTKQLPLTVGCDSQSPKEQRSAASMTINQAMTPSSLAYTPSKLASTPATPVSFYDSNADINLESDNFPLKDNPRYAKDGYPKKCGNSQLNRVLDSDKRQDFSGESRRRRSGSPISHMQHRNLIDNMKGRRNSNTINSIFNYKSQHYEMPYDDMMKNENINAQSMPFSVNGVNNENSIGGVITRADDAPLQHSVVKSCTPDGKEEMNRLKSNDSNEYSKSEGQIRTNSQLSKDILMGEPGDMVDLSSFVNAQRKASNETGDLVFSLSQDDDALKTFHASNSAATSNESWCISDDALGKQAQDSEVRRKRKSKLGLFRHIFSRK
SIO_010081: YCL051W
subclass of: SO_0000673
so part of: YCL051W
location: 35865..37616
location: region:35865-37616:1
so has part: feature:35865-37616:1:exon

NP_009879.2
type: Protein
SIO_000068: ncbiprotein

S000000556
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:35865-37616:1:exon

YCL050C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: DTP1
gene: APA1
locus tag: YCL050C
gene synonym: DTP1
so part of: sequence
location: complement(<37836..>38801)
location: region:37836-38801:-1
so has part: feature:37836-38801:-1:exon
subclass of: SO_0000010

850307
type: Gene
SIO_000068: ncbigene

position:37836:-1
position: 37836
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:38801:-1
position: 38801
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:37836-38801:-1:exon

YCL050C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: DTP1
gene: APA1
locus tag: YCL050C
gene synonym: DTP1
product: bifunctional AP-4-A phosphorylase/ADP sulfurylase
transcript id: NM_001178695.1
SIO_010081: YCL050C
subclass of: SO_0000673
so part of: YCL050C
location: complement(<37836..>38801)
location: region:37836-38801:-1
so has part: feature:37836-38801:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:37836-38801:-1:exon

YCL050C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: DTP1
gene: APA1
locus tag: YCL050C
gene synonym: DTP1
EC number: 2.7.7.5
EC number: 2.7.7.53
experiment: EXISTENCE:direct assay:GO:0004780 sulfate adenylyltransferase (ADP) activity [PMID:2556364]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0008796 bis(5'-nucleosyl)-tetraphosphatase activity [PMID:2174863|PMID:2556364]
experiment: EXISTENCE:direct assay:GO:0009164 nucleoside catabolic process [PMID:2174863]
experiment: EXISTENCE:direct assay:GO:0009165 nucleotide biosynthetic process [PMID:2172926]
experiment: EXISTENCE:genetic interaction:GO:0008796 bis(5'-nucleosyl)-tetraphosphatase activity [PMID:2174863]
experiment: EXISTENCE:genetic interaction:GO:0009164 nucleoside catabolic process [PMID:2174863]
experiment: EXISTENCE:mutant phenotype:GO:0004780 sulfate adenylyltransferase (ADP) activity [PMID:2556364]
experiment: EXISTENCE:mutant phenotype:GO:0008796 bis(5'-nucleosyl)-tetraphosphatase activity [PMID:2174863|PMID:2556364]
experiment: EXISTENCE:mutant phenotype:GO:0009164 nucleoside catabolic process [PMID:2174863]
note: AP4A phosphorylase; bifunctional diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase and ADP sulfurylase involved in catabolism of bis(5'-nucleosidyl) tetraphosphates; catalyzes phosphorolysis of dinucleoside oligophosphates, cleaving substrates' alpha/beta-anhydride bond and introducing Pi into the beta-position of the corresponding NDP formed; protein abundance increases under DNA replication stress; APA1 has a paralog, APA2, that arose from the whole genome duplication
codon start: 1
product: bifunctional AP-4-A phosphorylase/ADP sulfurylase
translation: MSIPADIASLISDKYKSAFDNGNLKFIQTETTKTKDPKTSMPYLISHMPSLIEKPERGQTPEGEDPLGKPEEELTVIPEFGGADNKAYKLLLNKFPVIPEHTLLVTNEYQHQTDALTPTDLLTAYKLLCALDNEESDKRHMVFYNSGPASGSSLDHKHLQILQMPEKFVTFQDRLCNGKEHFLPTFNTEPLQDAKVSFAHFVLPMPESEETVDEDLLAMCYISILQRALTFFQDWLNENPELKKSYNLMLTKEWICVVPRSKAFSDEMKIGFNSTGYCGMILTKNDEVFSKITEKPELINDILLECGFPNTSGQKPNEYNY
SIO_010081: YCL050C
subclass of: SO_0000673
so part of: YCL050C
location: complement(37836..38801)
location: region:37836-38801:-1
so has part: feature:37836-38801:-1:exon

NP_009880.2
type: Protein
SIO_000068: ncbiprotein

S000000555
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:37836-38801:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS305; Efficient early-firing replication origin on Chromosome III
so part of: sequence
location: 39508..39595
location: region:39508-39595:1
so has part: feature:39508-39595:1:region

S000028482
type: SGD
SIO_000068: sgd

position:39508:1
position: 39508
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:39595:1
position: 39595
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:39508-39595:1:region

YCL049C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCL049C
so part of: sequence
location: complement(<39786..>40724)
location: region:39786-40724:-1
so has part: feature:39786-40724:-1:exon
subclass of: SO_0000010

850308
type: Gene
SIO_000068: ncbigene

position:39786:-1
position: 39786
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:40724:-1
position: 40724
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:39786-40724:-1:exon

YCL049C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCL049C
product: uncharacterized protein
transcript id: NM_001178694.1
SIO_010081: YCL049C
subclass of: SO_0000673
so part of: YCL049C
location: complement(<39786..>40724)
location: region:39786-40724:-1
so has part: feature:39786-40724:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:39786-40724:-1:exon

YCL049C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YCL049C
experiment: EXISTENCE:direct assay:GO:0016020 membrane [PMID:11935221]
note: hypothetical protein; localizes to membrane fraction; YCL049C is not an essential gene
codon start: 1
product: uncharacterized protein
translation: MFSKYLVTASSLFVALTSAASTVDLDALLLLPGVESHDGVDTVFSTKDFYQVSFVKSIAPAIVNSSVIFHDVSRGVAMGNVKSRASIFNPEETYYDWEQYQVVNNGDWRTEWAPASDCIWREEKDNSDETPDRFPISVPYNWTSQYSIVDYDTDANEDNLDFRFIKSLLDKKNWLKKINQTVSQSSIMVAPMIRPYNVVQLWYSKDMVWANVQRQYCSGVYPGGTQCSAWSRYYHVDAPTCDEPVASYMTKMLENEVQCPNERNATTLEPLRLNKQGDSDFSLTFEEEEEEETGSKSLWSTLKKIFSKRSIS
SIO_010081: YCL049C
subclass of: SO_0000673
so part of: YCL049C
location: complement(39786..40724)
location: region:39786-40724:-1
so has part: feature:39786-40724:-1:exon

NP_009881.2
type: Protein
SIO_000068: ncbiprotein

S000000554
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:39786-40724:-1:exon

YCL048W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCL048W-A
so part of: sequence
location: <41488..>41727
location: region:41488-41727:1
so has part: feature:41488-41727:1:exon
subclass of: SO_0000010

3799968
type: Gene
SIO_000068: ncbigene

position:41488:1
position: 41488
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:41727:1
position: 41727
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:41488-41727:1:exon

YCL048W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCL048W-A
product: uncharacterized protein
transcript id: NM_001184678.1
SIO_010081: YCL048W-A
subclass of: SO_0000673
so part of: YCL048W-A
location: <41488..>41727
location: region:41488-41727:1
so has part: feature:41488-41727:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:41488-41727:1:exon

YCL048W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YCL048W-A
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
note: hypothetical protein; SWAT-GFP and mCherry fusion proteins localize to the cell periphery and vacuole; YCL048W-A has a paralog, YDR524C-B, that arose from the whole genome duplication
codon start: 1
product: uncharacterized protein
translation: MQIKNIVAVLATVTAINAQVGIEPNATTPNATQPNATQPNTTLPTASVTTTVSIGEAVVNTMAAGAFGAAIAAGVAFLF
SIO_010081: YCL048W-A
subclass of: SO_0000673
so part of: YCL048W-A
location: 41488..41727
location: region:41488-41727:1
so has part: feature:41488-41727:1:exon

NP_001032573.1
type: Protein
SIO_000068: ncbiprotein

S000087203
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:41488-41727:1:exon

YCL048W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SPS22
locus tag: YCL048W
so part of: sequence
location: <42165..>43556
location: region:42165-43556:1
so has part: feature:42165-43556:1:exon
subclass of: SO_0000010

850309
type: Gene
SIO_000068: ncbigene

position:42165:1
position: 42165
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:43556:1
position: 43556
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:42165-43556:1:exon

YCL048W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SPS22
locus tag: YCL048W
product: Sps22p
transcript id: NM_001178693.1
SIO_010081: YCL048W
subclass of: SO_0000673
so part of: YCL048W
location: <42165..>43556
location: region:42165-43556:1
so has part: feature:42165-43556:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:42165-43556:1:exon

YCL048W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SPS22
locus tag: YCL048W
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0030476 ascospore wall assembly [PMID:15590821]
note: hypothetical protein; SPS22 has a paralog, SPS2, that arose from the whole genome duplication; redundant with Sps2p for the organization of the beta-glucan layer of the spore wall
codon start: 1
product: Sps22p
translation: MNRITRKSCLFAIIFASLFVTHALGAAIDPPRRPHNVKPFHNGNLELQRRANEPFFEIDVKSLNTNSPISELCKKDLHVIESSHDLFHLQNQCEFILGSLKVTNYDSNILDLNSLRAIGGDLIIQDSPELIRIQAGNLNKIEGLFQLQGLTSLVSVEIPTLKFCQSLEWKVVPILNYVSMDSQNIEIIKDIVISDTSLANIENFNKVQEIDTFNINNNRFLETIHSNVKTIRGQFSVHANAKELELEMPHLREVENITIRDTSLVYLPQLTKVKSSLEFIENYFYELNLNNLQKIGGTLGIINNVNLIKVNLENLTDIQGGLMIADNESLEDITFLPNLKQIGGAIFFEGSFKDIMFDSLKLVKGSAFIKSSSNVLDCNKWTNPSNGRSIIRGGKFTCISGKKENTLNVKQDGTIIEKGYKDLTQEGEDSKKRVISKYANSANPSMQLDPLLFGTCLVAMLLF
SIO_010081: YCL048W
subclass of: SO_0000673
so part of: YCL048W
location: 42165..43556
location: region:42165-43556:1
so has part: feature:42165-43556:1:exon

NP_009882.1
type: Protein
SIO_000068: ncbiprotein

S000000553
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:42165-43556:1:exon

YCL047C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: POF1
locus tag: YCL047C
so part of: sequence
location: complement(<43661..>44437)
location: region:43661-44437:-1
so has part: feature:43661-44437:-1:exon
subclass of: SO_0000010

850310
type: Gene
SIO_000068: ncbigene

position:43661:-1
position: 43661
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:44437:-1
position: 44437
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:43661-44437:-1:exon

YCL047C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: POF1
locus tag: YCL047C
product: nicotinamide-nucleotide adenylyltransferase
transcript id: NM_001178692.1
SIO_010081: YCL047C
subclass of: SO_0000673
so part of: YCL047C
location: complement(<43661..>44437)
location: region:43661-44437:-1
so has part: feature:43661-44437:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:43661-44437:-1:exon

YCL047C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: POF1
locus tag: YCL047C
EC number: 2.7.7.1
experiment: EXISTENCE:direct assay:GO:0000309 nicotinamide-nucleotide adenylyltransferase activity [PMID:24759102]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:24759102]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:24759102]
experiment: EXISTENCE:direct assay:GO:0016887 ATP hydrolysis activity [PMID:22204397]
experiment: EXISTENCE:genetic interaction:GO:0000309 nicotinamide-nucleotide adenylyltransferase activity [PMID:24759102]
experiment: EXISTENCE:genetic interaction:GO:0001403 invasive growth in response to glucose limitation [PMID:21460040]
experiment: EXISTENCE:genetic interaction:GO:0007124 pseudohyphal growth [PMID:21460040]
experiment: EXISTENCE:genetic interaction:GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway [PMID:24759102]
experiment: EXISTENCE:mutant phenotype:GO:0030433 ubiquitin-dependent ERAD pathway [PMID:22204397]
experiment: EXISTENCE:physical interaction:GO:0030433 ubiquitin-dependent ERAD pathway [PMID:22204397]
note: Nicotinamide mononucleotide-specific adenylyltransferase (NMNAT); catalyzes the conversion of nicotinamide mononucleotide (NMN) to nicotinamide adenine dinucleotide (NAD+); role in the nicotinamide riboside (NR) salvage pathway of NAD+ biosynthesis; involved in NR and NAD+ homeostasis; ATPase involved in protein quality control and filamentation pathways; interacts physically with Kss1p and suppresses the filamentation defect of a kss1 deletion
codon start: 1
product: nicotinamide-nucleotide adenylyltransferase
translation: MKKTFEQFRKSNLLFQVLKGPQHLECQKLFVLDSSFNPPHLAHFQLLSQTIKNFKLKDTRSHVLLLLAVNNADKLPKPASFPTRLEMMCLFADYLQEKLPQSVVSVGLTVFSKFIDKDKILHEQFVKGCSADIGYLVGFDTIARIFDEKYYHPLKISDVMESFMSGSQLYCLARGDCHLSAESQLRYASDILEGKFEPVIPREWGARIHVMQNDYPALRNVSSSEIRNKLKNGQVESLKDELPLCIYDYLINNKTIFD
SIO_010081: YCL047C
subclass of: SO_0000673
so part of: YCL047C
location: complement(43661..44437)
location: region:43661-44437:-1
so has part: feature:43661-44437:-1:exon

NP_009883.1
type: Protein
SIO_000068: ncbiprotein

S000000552
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:43661-44437:-1:exon

YCL045C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: EMC1
locus tag: YCL045C
so part of: sequence
location: complement(<44623..>46905)
location: region:44623-46905:-1
so has part: feature:44623-46905:-1:exon
subclass of: SO_0000010

850312
type: Gene
SIO_000068: ncbigene

position:44623:-1
position: 44623
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:46905:-1
position: 46905
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:44623-46905:-1:exon

YCL045C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: EMC1
locus tag: YCL045C
product: Emc1p
transcript id: NM_001178690.1
SIO_010081: YCL045C
subclass of: SO_0000673
so part of: YCL045C
location: complement(<44623..>46905)
location: region:44623-46905:-1
so has part: feature:44623-46905:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:44623-46905:-1:exon

YCL045C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: EMC1
locus tag: YCL045C
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:14562095|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0072546 EMC complex [PMID:19325107]
experiment: EXISTENCE:genetic interaction:GO:0034975 protein folding in endoplasmic reticulum [PMID:19325107]
note: Member of conserved endoplasmic reticulum membrane complex; involved in efficient folding of proteins in the ER; null mutant displays induction of the unfolded protein response; interacts with Gal80p; homologous to worm H17B01.4/EMC-1, fly CG2943, and human KIAA0090
codon start: 1
product: Emc1p
translation: MKITCTDLVYVFILLFLNTSCVQAVFSDDAFITDWQLANLGPWEKVIPDSRDRNRVLILSNPTETSCLVSSFNVSSGQILFRNVLPFTIDEIQLDSNDHNAMVCVNSSSNHWQKYDLHDWFLLEEGVDNAPSTTILPQSSYLNDQVSIKNNELHILDEQSKLAEWKLELPQGFNKVEYFHREDPLALVLNVNDTQYMGFSANGTELIPVWQRDEWLTNVVDYAVLDVFDSRDVELNKDMKAELDSNSLWNAYWLRLTTNWNRLINLLKENQFSPGRVFTKLLALDAKDTTVSDLKFGFAKILIVLTHDGFIGGLDMVNKGQLIWKLDLEIDQGVKMFWTDKNHDELVVFSHDGHYLTIEVTKDQPIIKSRSPLSERKTVDSVIRLNEHDHQYLIKFEDKDHLLFKLNPGKNTDVPIVANNHSSSHIFVTEHDTNGIYGYIIENDTVKQTWKKAVNSKEKMVAYSKRETTNLNTLGITLGDKSVLYKYLYPNLAAYLIANEEHHTITFNLIDTITGEILITQEHKDSPDFRFPMDIVFGEYWVVYSYFSSEPVPEQKLVVVELYESLTPDERLSNSSDNFSYDPLTGHINKPQFQTKQFIFPEIIKTMSISKTTDDITTKAIVMELENGQITYIPKLLLNARGKPAEEMAKDKKKEFMATPYTPVIPINDNFIITHFRNLLPGSDSQLISIPTNLESTSIICDLGLDVFCTRITPSGQFDLMSPTFEKGKLLITIFVLLVITYFIRPSVSNKKLKSQWLIK
SIO_010081: YCL045C
subclass of: SO_0000673
so part of: YCL045C
location: complement(44623..46905)
location: region:44623-46905:-1
so has part: feature:44623-46905:-1:exon

NP_009884.1
type: Protein
SIO_000068: ncbiprotein

S000000550
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:44623-46905:-1:exon

YCL044C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MGR1
locus tag: YCL044C
so part of: sequence
location: complement(<47111..>48364)
location: region:47111-48364:-1
so has part: feature:47111-48364:-1:exon
subclass of: SO_0000010

850313
type: Gene
SIO_000068: ncbigene

position:47111:-1
position: 47111
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:48364:-1
position: 48364
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:47111-48364:-1:exon

YCL044C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MGR1
locus tag: YCL044C
product: Mgr1p
transcript id: NM_001178689.1
SIO_010081: YCL044C
subclass of: SO_0000673
so part of: YCL044C
location: complement(<47111..>48364)
location: region:47111-48364:-1
so has part: feature:47111-48364:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:47111-48364:-1:exon

YCL044C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MGR1
locus tag: YCL044C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:14562095|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0031942 i-AAA complex [PMID:18843051|PMID:16267274]
experiment: EXISTENCE:direct assay:GO:0051787 misfolded protein binding [PMID:18843051]
experiment: EXISTENCE:mutant phenotype:GO:0006515 protein quality control for misfolded or incompletely synthesized proteins [PMID:18843051]
note: Subunit of the mitochondrial (mt) i-AAA protease supercomplex; i-AAA degrades misfolded mitochondrial proteins; forms a subcomplex with Mgr3p that binds to substrates to facilitate proteolysis; required for growth of cells lacking mtDNA
codon start: 1
product: Mgr1p
translation: MAVFTPPSGNSNSTDHTHTQDDHDKDDNDIKKFYIRPSLGLKLWGPLVPAPDNLPGLYTLITIQSAVGFFALWRLRRLYKLPPPRRIATGTHSDLSFGELPSEMIVNGKTKIKKDIADFPTLNRFSTTHGDIVLAPPPIIPRQSRFVSVRKLLWGLFGSLLLSQSLLELTRLNFLKYDPWCDEMKSVRDKKFFNNIVKYYHEGIDPTKIKVKDAMNGTPLSTNIPEVKQSVALARAQVEAQNPIIKWFGPLEYKPMSFNEYLNRMEFHLDMFEFFQNKRNIRENSIELINSISHNPQSSSTGLEGLSESKKLHLQNVEKRLHFLASSGDSISAPVKKRSSTTLSRGVILPHDTKGPQDIDLDTIRSLYDPWMTLALETSLSIKFIPTTMPSHTKTPTSTDQPLPGPTPKALTNEKTH
SIO_010081: YCL044C
subclass of: SO_0000673
so part of: YCL044C
location: complement(47111..48364)
location: region:47111-48364:-1
so has part: feature:47111-48364:-1:exon

NP_009886.1
type: Protein
SIO_000068: ncbiprotein

S000000549
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:47111-48364:-1:exon

YCL043C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MFP1
alternative label: TRG1
gene: PDI1
locus tag: YCL043C
gene synonym: MFP1; TRG1
so part of: sequence
location: complement(<48653..>50221)
location: region:48653-50221:-1
so has part: feature:48653-50221:-1:exon
subclass of: SO_0000010

850314
type: Gene
SIO_000068: ncbigene

position:48653:-1
position: 48653
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:50221:-1
position: 50221
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:48653-50221:-1:exon

YCL043C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MFP1
alternative label: TRG1
gene: PDI1
locus tag: YCL043C
gene synonym: MFP1; TRG1
product: protein disulfide isomerase PDI1
transcript id: NM_001178688.1
SIO_010081: YCL043C
subclass of: SO_0000673
so part of: YCL043C
location: complement(<48653..>50221)
location: region:48653-50221:-1
so has part: feature:48653-50221:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:48653-50221:-1:exon

YCL043C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MFP1
alternative label: TRG1
gene: PDI1
locus tag: YCL043C
gene synonym: MFP1; TRG1
EC number: 5.3.4.1
experiment: EXISTENCE:direct assay:GO:0003756 protein disulfide isomerase activity [PMID:16002399|PMID:16413482]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005788 endoplasmic reticulum lumen [PMID:1761554]
experiment: EXISTENCE:direct assay:GO:0015035 protein-disulfide reductase activity [PMID:16002399]
experiment: EXISTENCE:direct assay:GO:0036508 protein alpha-1,2-demannosylation [PMID:21700223]
experiment: EXISTENCE:direct assay:GO:0051082 unfolded protein binding [PMID:16002399]
experiment: EXISTENCE:direct assay:GO:1904382 mannose trimming involved in glycoprotein ERAD pathway [PMID:21700223|PMID:27053108]
experiment: EXISTENCE:genetic interaction:GO:1904382 mannose trimming involved in glycoprotein ERAD pathway [PMID:21700223]
experiment: EXISTENCE:mutant phenotype:GO:0003756 protein disulfide isomerase activity [PMID:11157982]
experiment: EXISTENCE:mutant phenotype:GO:0006457 protein folding [PMID:11157982]
experiment: EXISTENCE:mutant phenotype:GO:1904382 mannose trimming involved in glycoprotein ERAD pathway [PMID:21700223]
experiment: EXISTENCE:physical interaction:GO:0005515 protein binding [PMID:16002399]
note: Protein disulfide isomerase; multifunctional oxidoreductase of the ER lumen, essential for disulfide bond formation in secretory and cell-surface proteins, processing of non-native disulfide bonds; Ero1p activator; complexes with exomannosidase, Mnl1p to facilitate the recognition of misfolded glycoproteins and the trimming of glycan Man8GlcNAc2 to Man7GlcNAc2 on substrates, thereby accelerating ERAD; PDI1 has a paralog, EUG1, that arose from the whole genome duplication
codon start: 1
product: protein disulfide isomerase PDI1
translation: MKFSAGAVLSWSSLLLASSVFAQQEAVAPEDSAVVKLATDSFNEYIQSHDLVLAEFFAPWCGHCKNMAPEYVKAAETLVEKNITLAQIDCTENQDLCMEHNIPGFPSLKIFKNSDVNNSIDYEGPRTAEAIVQFMIKQSQPAVAVVADLPAYLANETFVTPVIVQSGKIDADFNATFYSMANKHFNDYDFVSAENADDDFKLSIYLPSAMDEPVVYNGKKADIADADVFEKWLQVEALPYFGEIDGSVFAQYVESGLPLGYLFYNDEEELEEYKPLFTELAKKNRGLMNFVSIDARKFGRHAGNLNMKEQFPLFAIHDMTEDLKYGLPQLSEEAFDELSDKIVLESKAIESLVKDFLKGDASPIVKSQEIFENQDSSVFQLVGKNHDEIVNDPKKDVLVLYYAPWCGHCKRLAPTYQELADTYANATSDVLIAKLDHTENDVRGVVIEGYPTIVLYPGGKKSESVVYQGSRSLDSLFDFIKENGHFDVDGKALYEEAQEKAAEEADADAELADEEDAIHDEL
SIO_010081: YCL043C
subclass of: SO_0000673
so part of: YCL043C
location: complement(48653..50221)
location: region:48653-50221:-1
so has part: feature:48653-50221:-1:exon

NP_009887.1
type: Protein
SIO_000068: ncbiprotein

S000000548
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:48653-50221:-1:exon

YCL042W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCL042W
so part of: sequence
location: <50584..>50943
location: region:50584-50943:1
so has part: feature:50584-50943:1:exon
subclass of: SO_0000010

850315
type: Gene
SIO_000068: ncbigene

position:50584:1
position: 50584
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:50943:1
position: 50943
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:50584-50943:1:exon

YCL042W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCL042W
product: uncharacterized protein
transcript id: NM_001178687.1
SIO_010081: YCL042W
subclass of: SO_0000673
so part of: YCL042W
location: <50584..>50943
location: region:50584-50943:1
so has part: feature:50584-50943:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:50584-50943:1:exon

YCL042W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YCL042W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276]
note: hypothetical protein; epitope-tagged protein localizes to the cytoplasm
codon start: 1
product: uncharacterized protein
translation: MEKKKILDAALAPRIISGVPTDGQPLSGGPLSWAWCHTTLKRWALMKTRPYKYPLSTEPPTPPSVPNSASVNHNTTTNTTLSYTRCHSTTYTKPLRERSSRPWTRSATISRLPPRSWTN
SIO_010081: YCL042W
subclass of: SO_0000673
so part of: YCL042W
location: 50584..50943
location: region:50584-50943:1
so has part: feature:50584-50943:1:exon

NP_009889.2
type: Protein
SIO_000068: ncbiprotein

S000000547
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:50584-50943:1:exon

YCL040W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: HOR3
gene: GLK1
locus tag: YCL040W
gene synonym: HOR3
so part of: sequence
location: <50838..>52340
location: region:50838-52340:1
so has part: feature:50838-52340:1:exon
subclass of: SO_0000010

850317
type: Gene
SIO_000068: ncbigene

position:50838:1
position: 50838
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:52340:1
position: 52340
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:50838-52340:1:exon

YCL040W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: HOR3
gene: GLK1
locus tag: YCL040W
gene synonym: HOR3
product: glucokinase
transcript id: NM_001178685.1
SIO_010081: YCL040W
subclass of: SO_0000673
so part of: YCL040W
location: <50838..>52340
location: region:50838-52340:1
so has part: feature:50838-52340:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:50838-52340:1:exon

YCL040W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: HOR3
gene: GLK1
locus tag: YCL040W
gene synonym: HOR3
EC number: 2.7.1.2
experiment: EXISTENCE:direct assay:GO:0004340 glucokinase activity [PMID:8501032]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:16622836]
experiment: EXISTENCE:direct assay:GO:0006013 mannose metabolic process [PMID:237183]
experiment: EXISTENCE:direct assay:GO:0006096 glycolytic process [PMID:8501032]
experiment: EXISTENCE:genetic interaction:GO:0046323 glucose import [PMID:6300872]
experiment: EXISTENCE:mutant phenotype:GO:0004340 glucokinase activity [PMID:6341351]
experiment: EXISTENCE:mutant phenotype:GO:0006006 glucose metabolic process [PMID:6300872]
note: Glucokinase; catalyzes the phosphorylation of glucose at C6 in the first irreversible step of glucose metabolism; one of three glucose phosphorylating enzymes; expression regulated by non-fermentable carbon sources; GLK1 has a paralog, EMI2, that arose from the whole genome duplication
codon start: 1
product: glucokinase
translation: MSFDDLHKATERAVIQAVDQICDDFEVTPEKLDELTAYFIEQMEKGLAPPKEGHTLASDKGLPMIPAFVTGSPNGTERGVLLAADLGGTNFRICSVNLHGDHTFSMEQMKSKIPDDLLDDENVTSDDLFGFLARRTLAFMKKYHPDELAKGKDAKPMKLGFTFSYPVDQTSLNSGTLIRWTKGFRIADTVGKDVVQLYQEQLSAQGMPMIKVVALTNDTVGTYLSHCYTSDNTDSMTSGEISEPVIGCIFGTGTNGCYMEEINKITKLPQELRDKLIKEGKTHMIINVEWGSFDNELKHLPTTKYDVVIDQKLSTNPGFHLFEKRVSGMFLGEVLRNILVDLHSQGLLLQQYRSKEQLPRHLTTPFQLSSEVLSHIEIDDSTGLRETELSLLQSLRLPTTPTERVQIQKLVRAISRRSAYLAAVPLAAILIKTNALNKRYHGEVEIGCDGSVVEYYPGFRSMLRHALALSPLGAEGERKVHLKIAKDGSGVGAALCALVA
SIO_010081: YCL040W
subclass of: SO_0000673
so part of: YCL040W
location: 50838..52340
location: region:50838-52340:1
so has part: feature:50838-52340:1:exon

NP_009890.1
type: Protein
SIO_000068: ncbiprotein

S000000545
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:50838-52340:1:exon

YCL039W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MOH2
gene: GID7
locus tag: YCL039W
gene synonym: MOH2
so part of: sequence
location: <52645..>54882
location: region:52645-54882:1
so has part: feature:52645-54882:1:exon
subclass of: SO_0000010

850318
type: Gene
SIO_000068: ncbigene

position:52645:1
position: 52645
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:54882:1
position: 54882
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:52645-54882:1:exon

YCL039W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MOH2
gene: GID7
locus tag: YCL039W
gene synonym: MOH2
product: glucose-induced degradation complex subunit GID7
transcript id: NM_001178684.1
SIO_010081: YCL039W
subclass of: SO_0000673
so part of: YCL039W
location: <52645..>54882
location: region:52645-54882:1
so has part: feature:52645-54882:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:52645-54882:1:exon

YCL039W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MOH2
gene: GID7
locus tag: YCL039W
gene synonym: MOH2
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005777 peroxisome [PMID:36164978]
experiment: EXISTENCE:direct assay:GO:0034657 GID complex [PMID:18508925]
experiment: EXISTENCE:mutant phenotype:GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process [PMID:12686616]
experiment: EXISTENCE:mutant phenotype:GO:0045721 negative regulation of gluconeogenesis [PMID:12686616]
note: Subunit of GID Complex that binds directly to central component Vid30p; GID complex is involved in proteasome-dependent catabolite inactivation of fructose-1,6-bisphosphatase; Gid7p contains six WD40 repeats; localizes to peroxisomes in oleate-growing cells; computational analysis suggests that Gid7p and Moh1p have similar functions
codon start: 1
product: glucose-induced degradation complex subunit GID7
translation: MSHTNKIAYVLNNDTEETASPSSVGCFDKKQLTKLLIHTLKELGYDSAANQLLLESGGYQNESNHIQTFFKLIKTGQFHLINWQIVCSLPLAHSSPLRSEWLQRLLIPTPTPATTSLFDHMLLQLQYLQQLMSSVNSSTCSDAEIATLRNYVEIMILVNRQIFLEFFHPVTNSASHKGPHTALPVLYLRKILKNFIEIWDSLLVSNDQFLNEENIFNPETTLRELSTYLTNPKLTAQLNLERDHLIDAISKYIDPNELVPKGRLLHLLKQAIKYQQSQDIFNIIDPDDDASFSSPPHRINLLQDNFSHDLTVTFQEWKTIQDTTDEIWFLTFSPNGKYLASATSESSRGYFITVYDVEQDFKIYKTCVSLSQSVLYLMFSPDSRYLVACPFSEDVTIYDMNATSLPDASATDSFLLYPSTRLSPMDSFKLDTTTYPDDTESSASSSSRPANANSNQSRVWCCDAFHTAERAGWMVVGSPDREAIVHSLTTKESLFSLKGRTCIALGHDENISGRKSIDPAKVLYKPTSSNGNWQYVEDDETFPRVHDVKISYDDKYVLLMTHQGVIDVYDFSGFPSKEELSKQTVDPKNFLIPRIARLDVGKNMTCISLPLNTTHQGFHRQQISESQHLVLVSLQDNELQMWDYKENILIQKYFGQKQQHFIIRSCFAYGNKLVMSGSEDGKIYIWDRIRGNLVSVLSGHSTVMSNSTKPMGKNCNVVASNPADKEMFASGGDDGKIKIWKISRN
SIO_010081: YCL039W
subclass of: SO_0000673
so part of: YCL039W
location: 52645..54882
location: region:52645-54882:1
so has part: feature:52645-54882:1:exon

NP_009891.1
type: Protein
SIO_000068: ncbiprotein

S000000544
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:52645-54882:1:exon

YCL038C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: AUT4
gene: ATG22
locus tag: YCL038C
gene synonym: AUT4
so part of: sequence
location: complement(<54941..>56527)
location: region:54941-56527:-1
so has part: feature:54941-56527:-1:exon
subclass of: SO_0000010

850319
type: Gene
SIO_000068: ncbigene

position:54941:-1
position: 54941
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:56527:-1
position: 56527
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:54941-56527:-1:exon

YCL038C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: AUT4
gene: ATG22
locus tag: YCL038C
gene synonym: AUT4
product: Atg22p
transcript id: NM_001178683.1
SIO_010081: YCL038C
subclass of: SO_0000673
so part of: YCL038C
location: complement(<54941..>56527)
location: region:54941-56527:-1
so has part: feature:54941-56527:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:54941-56527:-1:exon

YCL038C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: AUT4
gene: ATG22
locus tag: YCL038C
gene synonym: AUT4
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:17021250]
experiment: EXISTENCE:mutant phenotype:GO:0032974 amino acid transmembrane export from vacuole [PMID:17021250]
note: Vacuolar membrane protein; required for efflux of amino acids during autophagic body breakdown in vacuole; targeted to vacuole via AP-3 pathway; null mutation causes gradual loss of viability during starvation
codon start: 1
product: Atg22p
translation: MSYGTINDMNESVTNYRIKKAQNNIKGWYAYSFSSEPFVVSAVSTYIPLLLQQFASINGVKVHDHSIPCLSETGSDSDKCVLGLFNNRIFVDTSSFALYVFSLSVLFQTIIVISVSGIVDLWGSVKFKGRILVWFGIVGALSTVAISKLNDTQIYSLAGLYIVANGCFGVINVVGNSLLPIFVKDSLKCQSQGAYEPDKVDSLTTVISGRGASLGYSSALIVQIVSMFLVASKKGSKQDVQVAVLFVGIWWFVWQLPMIWLIDDVTIPIRVDDSTLASARSPYPGEQDALGQLNWKNYLSYGWVSLFESFKHARLLKDVMIFLIAWFIISDSITTINSTAVLFSKAELHMSTLNLIMISVLTVVNAMLGAFMIPQFLATKFRWTSSQTLMYIIIWASFIPFYGILGFFFNAFGLKHKFEMFLLAIWYGLSLGGLSAVSRSVFSLIVPPGKESTFFSMFSITDKGSSILGPFLVGLLTDKTHNIRYSFYFFFLLLMLSLPVLNCLDVKRGRREAEELSQVLPESERRLD
SIO_010081: YCL038C
subclass of: SO_0000673
so part of: YCL038C
location: complement(54941..56527)
location: region:54941-56527:-1
so has part: feature:54941-56527:-1:exon

NP_009892.1
type: Protein
SIO_000068: ncbiprotein

S000000543
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:54941-56527:-1:exon

YCL037C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SRO9
locus tag: YCL037C
so part of: sequence
location: complement(<57374..>58678)
location: region:57374-58678:-1
so has part: feature:57374-58678:-1:exon
subclass of: SO_0000010

850320
type: Gene
SIO_000068: ncbigene

position:57374:-1
position: 57374
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:58678:-1
position: 58678
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:57374-58678:-1:exon

YCL037C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SRO9
locus tag: YCL037C
product: Sro9p
transcript id: NM_001178682.1
SIO_010081: YCL037C
subclass of: SO_0000673
so part of: YCL037C
location: complement(<57374..>58678)
location: region:57374-58678:-1
so has part: feature:57374-58678:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:57374-58678:-1:exon

YCL037C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SRO9
locus tag: YCL037C
experiment: EXISTENCE:direct assay:GO:0003723 RNA binding [PMID:10564276]
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0005844 polysome [PMID:10564276]
experiment: EXISTENCE:direct assay:GO:0010494 cytoplasmic stress granule [PMID:23222640|PMID:26777405]
experiment: EXISTENCE:mutant phenotype:GO:0006417 regulation of translation [PMID:10564276]
note: Cytoplasmic RNA-binding protein; shuttles between nucleus and cytoplasm and is exported from the nucleus in an mRNA export-dependent manner; associates with translating ribosomes; involved in heme regulation of Hap1p as a component of the HMC complex, also involved in the organization of actin filaments; contains a La motif; SRO9 has a paralog, SLF1, that arose from the whole genome duplication
codon start: 1
product: Sro9p
translation: MSAETAAANTATAPVPEVQEQESSKSKQVNLTPAPLPTSSPWKLAPTEIPVSTISIEDLDATRKKKNRTPTPKSSTATKWVPIKASITVSGTKRSGSKNGASNGNSNKSKNNKTAASSTSSSNANRKKKHHQHNAKKQQQMKKDGFESAVGEEDSKDATSQENGQSTQQQQPPHHRNHHHSHHHNSNGPQRRKFHNSNNAGMPQNQGFPPQFKPYQGRNARNNNNNRSKYHNHFHHNQQHPQQPMVKLQQQFYPVQPVLMAINNIARQIEYYFSEENLTVDNYLRSKLSKDGFAPLSLISKFYRVVNMSFGGDTNLILAALREIVANEAATVNVAEGTLAAKEGDNVTGEAKEPSPLDKYFVRSKSWSNWLPETFETEINIEKELVGDALDQFMISLPPVPQQEEESSTELASQEQETKEDSAPVAAGESESSL
SIO_010081: YCL037C
subclass of: SO_0000673
so part of: YCL037C
location: complement(57374..58678)
location: region:57374-58678:-1
so has part: feature:57374-58678:-1:exon

NP_009893.2
type: Protein
SIO_000068: ncbiprotein

S000000542
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:57374-58678:-1:exon

YCL036W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YCD6
gene: GFD2
locus tag: YCL036W
gene synonym: YCD6
so part of: sequence
location: <59026..>60726
location: region:59026-60726:1
so has part: feature:59026-60726:1:exon
subclass of: SO_0000010

850321
type: Gene
SIO_000068: ncbigene

position:59026:1
position: 59026
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:60726:1
position: 60726
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:59026-60726:1:exon

YCL036W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YCD6
gene: GFD2
locus tag: YCL036W
gene synonym: YCD6
product: Gfd2p
transcript id: NM_001178681.1
SIO_010081: YCL036W
subclass of: SO_0000673
so part of: YCL036W
location: <59026..>60726
location: region:59026-60726:1
so has part: feature:59026-60726:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:59026-60726:1:exon

YCL036W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YCD6
gene: GFD2
locus tag: YCL036W
gene synonym: YCD6
note: hypothetical protein; identified as a high-copy suppressor of a dbp5 mutation; GFD2 has a paralog, YDR514C, that arose from the whole genome duplication
codon start: 1
product: Gfd2p
translation: MQVQKMVRDNSNNGSDKSVHWERRNNNGAGPRYRSRSGNTGALATKLSNGTLSVRGLVKDRTGSGKIAGCVEAFLDARTQLNTPWDRAKCNWLDQIDYYVQLRKTAFSKELDQLRKPMIDAYVAEMRQKFDASYGQSRAQLEAKLAQVDSEWHMVHGDVHAKLEKLVEERRFLKRLSDTIVPPRSKRSQRLSPLTKEDRANCICPQPKGMSDTAWFEAIQKKMLGMNGTIKLLETEQKLLADEKNSVRKTFWPMVEAHSRSNEFAYLEKCIRLMASQRAICFCLDIEAFETNQNVITEIGISIYDPRENMVPSMVPITKNYHLIIEESLELRNQKWVCDYKDCYLLGESYVLSLKECVHFIQSLINYYLVPVTEEDKTWSRAFVGHHVSGDLKWLETIGVKFPGRGYEGHLDHTLLLAETPGDLDVFILDTEQFYRKSYGEKGSSLGKILRLFEIPHAFLHNAGNDAYYTLHLFMKFCDVNFRKISGMDDVLKVMGQVKVWGERDVREPKVVPMSYAISIEEAVKNRTYRKGVKSSRKERVCQTEFGGLTYFGTAKDAFTSTLPTH
SIO_010081: YCL036W
subclass of: SO_0000673
so part of: YCL036W
location: 59026..60726
location: region:59026-60726:1
so has part: feature:59026-60726:1:exon

NP_009894.1
type: Protein
SIO_000068: ncbiprotein

S000000541
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:59026-60726:1:exon

YCL035C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GRX1
locus tag: YCL035C
so part of: sequence
location: complement(<60841..>61173)
location: region:60841-61173:-1
so has part: feature:60841-61173:-1:exon
subclass of: SO_0000010

850322
type: Gene
SIO_000068: ncbigene

position:60841:-1
position: 60841
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:61173:-1
position: 61173
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:60841-61173:-1:exon

YCL035C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GRX1
locus tag: YCL035C
product: dithiol glutaredoxin GRX1
transcript id: NM_001178680.1
SIO_010081: YCL035C
subclass of: SO_0000673
so part of: YCL035C
location: complement(<60841..>61173)
location: region:60841-61173:-1
so has part: feature:60841-61173:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:60841-61173:-1:exon

YCL035C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GRX1
locus tag: YCL035C
EC number: 1.11.1.9
EC number: 2.5.1.18
experiment: EXISTENCE:direct assay:GO:0004364 glutathione transferase activity [PMID:12684511]
experiment: EXISTENCE:direct assay:GO:0004602 glutathione peroxidase activity [PMID:18992757|PMID:11875065|PMID:12684511]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095|PMID:11914276]
experiment: EXISTENCE:genetic interaction:GO:0010731 protein glutathionylation [PMID:20074363]
experiment: EXISTENCE:mutant phenotype:GO:0034599 cellular response to oxidative stress [PMID:9571241]
note: Glutathione-dependent disulfide oxidoreductase; hydroperoxide and superoxide-radical responsive, heat-stable, with active site cysteine pair; protects cells from oxidative damage; GRX1 has a paralog, GRX2, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress
codon start: 1
product: dithiol glutaredoxin GRX1
translation: MVSQETIKHVKDLIAENEIFVASKTYCPYCHAALNTLFEKLKVPRSKVLVLQLNDMKEGADIQAALYEINGQRTVPNIYINGKHIGGNDDLQELRETGELEELLEPILAN
SIO_010081: YCL035C
subclass of: SO_0000673
so part of: YCL035C
location: complement(60841..61173)
location: region:60841-61173:-1
so has part: feature:60841-61173:-1:exon

NP_009895.1
type: Protein
SIO_000068: ncbiprotein

S000000540
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:60841-61173:-1:exon

YCL034W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: LSB5
locus tag: YCL034W
so part of: sequence
location: <61658..>62722
location: region:61658-62722:1
so has part: feature:61658-62722:1:exon
subclass of: SO_0000010

850323
type: Gene
SIO_000068: ncbigene

position:61658:1
position: 61658
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:62722:1
position: 62722
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:61658-62722:1:exon

YCL034W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: LSB5
locus tag: YCL034W
product: Lsb5p
transcript id: NM_001178679.1
SIO_010081: YCL034W
subclass of: SO_0000673
so part of: YCL034W
location: <61658..>62722
location: region:61658-62722:1
so has part: feature:61658-62722:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:61658-62722:1:exon

YCL034W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: LSB5
locus tag: YCL034W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:18298676]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005938 cell cortex [PMID:15651983|PMID:18298676|PMID:12388763]
experiment: EXISTENCE:direct assay:GO:0030479 actin cortical patch [PMID:15651983]
experiment: EXISTENCE:genetic interaction:GO:0006897 endocytosis [PMID:12388763]
experiment: EXISTENCE:genetic interaction:GO:0030036 actin cytoskeleton organization [PMID:12388763]
experiment: EXISTENCE:genetic interaction:GO:0051666 actin cortical patch localization [PMID:12388763]
experiment: EXISTENCE:physical interaction:GO:0007015 actin filament organization [PMID:10512884]
note: Protein involved in membrane-trafficking events at plasma membrane; interacts with actin regulators Sla1p and Las17p, ubiquitin, Arf3p to couple actin dynamics to membrane trafficking processes; similar structure to GGA family of proteins with N-terminal VHS domain and GAT domain; binds Las17p, which is homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly, actin polymerization; may mediate disassembly of Pan1 complex from endocytic coat
codon start: 1
product: Lsb5p
translation: MGFLSDHPHTAITETIFRIVSSRDYTLEVELAPLIQLIKADHNDYNYTVNQEEAARALRKKIKYGNRLQQSRTLDLLDLFISQGVKFTVMYNDDKLLQRLRGMATNSENSGSGEKYEPRIIKKCAAYAISWLNYITQNNLENARAYSGLYQLGQTVKQRYSKSSRSRRSGGGSGGRSNFMDDSADDTLYQSNSLTSADRLYRIPQINMNKEAPRIRLIISDALASAVSLQNSLIGLPKGKFSTDDEEATSKFIQARAIRRKVLRYLQLVTEGEFLGSLIHANDELVAALTAYDDRSAQDDSSDESDHGSYDDGIYDENEQDNSRYIDSESSEEESLSSYQPSTISNPFGDHNKI
SIO_010081: YCL034W
subclass of: SO_0000673
so part of: YCL034W
location: 61658..62722
location: region:61658-62722:1
so has part: feature:61658-62722:1:exon

NP_009896.2
type: Protein
SIO_000068: ncbiprotein

S000000539
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:61658-62722:1:exon

YCL033C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MXR2
locus tag: YCL033C
so part of: sequence
location: complement(<62776..>63282)
location: region:62776-63282:-1
so has part: feature:62776-63282:-1:exon
subclass of: SO_0000010

850324
type: Gene
SIO_000068: ncbigene

position:62776:-1
position: 62776
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:63282:-1
position: 63282
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:62776-63282:-1:exon

YCL033C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MXR2
locus tag: YCL033C
product: peptide-methionine (R)-S-oxide reductase
transcript id: NM_001178678.1
SIO_010081: YCL033C
subclass of: SO_0000673
so part of: YCL033C
location: complement(<62776..>63282)
location: region:62776-63282:-1
so has part: feature:62776-63282:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:62776-63282:-1:exon

YCL033C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MXR2
locus tag: YCL033C
EC number: 1.8.4.12
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:20799725]
experiment: EXISTENCE:direct assay:GO:0033743 peptide-methionine (R)-S-oxide reductase activity [PMID:15141092]
experiment: EXISTENCE:genetic interaction:GO:0034599 cellular response to oxidative stress [PMID:11929995]
experiment: EXISTENCE:mutant phenotype:GO:0033743 peptide-methionine (R)-S-oxide reductase activity [PMID:15141092]
experiment: EXISTENCE:mutant phenotype:GO:0034599 cellular response to oxidative stress [PMID:11929995]
note: Methionine-R-sulfoxide reductase; involved in the response to oxidative stress; protects iron-sulfur clusters from oxidative inactivation along with MXR1; involved in the regulation of lifespan
codon start: 1
product: peptide-methionine (R)-S-oxide reductase
translation: MNKWSRLYVITVRRTFPGRRNIVLTQYWNKSKKMSDESNDVKWNDALTPLQLMVLRDKATERPNTGAYLHTNESGVYHCANCDRPLYSSKAKFDARCGWPAFYEEVSPGAITYHRDNSLMPARVEICCARCGGHLGHVFEGEGWKQLLNLPKDTRHCVNSASLNLKKD
SIO_010081: YCL033C
subclass of: SO_0000673
so part of: YCL033C
location: complement(62776..63282)
location: region:62776-63282:-1
so has part: feature:62776-63282:-1:exon

NP_009897.1
type: Protein
SIO_000068: ncbiprotein

S000000538
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:62776-63282:-1:exon

YCL032W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: STE50
locus tag: YCL032W
so part of: sequence
location: <63441..>64481
location: region:63441-64481:1
so has part: feature:63441-64481:1:exon
subclass of: SO_0000010

850325
type: Gene
SIO_000068: ncbigene

position:63441:1
position: 63441
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:64481:1
position: 64481
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:63441-64481:1:exon

YCL032W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: STE50
locus tag: YCL032W
product: Ste50p
transcript id: NM_001178677.1
SIO_010081: YCL032W
subclass of: SO_0000673
so part of: YCL032W
location: <63441..>64481
location: region:63441-64481:1
so has part: feature:63441-64481:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:63441-64481:1:exon

YCL032W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: STE50
locus tag: YCL032W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:9742096]
experiment: EXISTENCE:direct assay:GO:0019887 protein kinase regulator activity [PMID:10397774]
experiment: EXISTENCE:direct assay:GO:0032093 SAM domain binding [PMID:16337230]
experiment: EXISTENCE:genetic interaction:GO:0000161 osmosensory signaling MAPK cascade [PMID:9742096]
experiment: EXISTENCE:mutant phenotype:GO:0000750 pheromone-dependent signal transduction involved in conjugation with cellular fusion [PMID:8793874]
experiment: EXISTENCE:mutant phenotype:GO:0001402 signal transduction involved in filamentous growth [PMID:9738877]
experiment: EXISTENCE:mutant phenotype:GO:0007232 osmosensory signaling pathway via Sho1 osmosensor [PMID:11370856]
experiment: EXISTENCE:physical interaction:GO:0000161 osmosensory signaling MAPK cascade [PMID:9742096]
note: Adaptor protein for various signaling pathways; involved in mating response, invasive/filamentous growth, osmotolerance; acts as an adaptor that links G protein-associated Cdc42p-Ste20p complex to the effector Ste11p to modulate signal transduction
codon start: 1
product: Ste50p
translation: MEDGKQAINEGSNDASPDLDVNGTILMNNEDFSQWSVDDVITWCISTLEVEETDPLCQRLRENDIVGDLLPELCLQDCQDLCDGDLNKAIKFKILINKMRDSKLEWKDDKTQEDMITVLKNLYTTTSAKLQEFQSQYTRLRMDVLDVMKTSSSSSPINTHGVSTTVPSSNNTIIPSSDGVSLSQTDYFDTVHNRQSPSRRESPVTVFRQPSLSHSKSLHKDSKNKVPQISTNQSHPSAVSTANTPGPSPNEALKQLRASKEDSCERILKNAMKRHNLADQDWRQYVLVICYGDQERLLELNEKPVIIFKNLKQQGLHPAIMLRRRGDFEEVAMMNGSDNVTPGGRL
SIO_010081: YCL032W
subclass of: SO_0000673
so part of: YCL032W
location: 63441..64481
location: region:63441-64481:1
so has part: feature:63441-64481:1:exon

NP_009898.1
type: Protein
SIO_000068: ncbiprotein

S000000537
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:63441-64481:1:exon

YCL031C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RRP7
locus tag: YCL031C
so part of: sequence
location: complement(<64675..>65568)
location: region:64675-65568:-1
so has part: feature:64675-65568:-1:exon
subclass of: SO_0000010

850326
type: Gene
SIO_000068: ncbigene

position:64675:-1
position: 64675
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:65568:-1
position: 65568
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:64675-65568:-1:exon

YCL031C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RRP7
locus tag: YCL031C
product: Rrp7p
transcript id: NM_001178676.1
SIO_010081: YCL031C
subclass of: SO_0000673
so part of: YCL031C
location: complement(<64675..>65568)
location: region:64675-65568:-1
so has part: feature:64675-65568:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:64675-65568:-1:exon

YCL031C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RRP7
locus tag: YCL031C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0019843 rRNA binding [PMID:24130456]
experiment: EXISTENCE:direct assay:GO:0032545 CURI complex [PMID:17452446]
experiment: EXISTENCE:direct assay:GO:0034456 UTP-C complex [PMID:17515605]
experiment: EXISTENCE:genetic interaction:GO:0000028 ribosomal small subunit assembly [PMID:9271380]
experiment: EXISTENCE:genetic interaction:GO:0006364 rRNA processing [PMID:9271380]
experiment: EXISTENCE:mutant phenotype:GO:0000028 ribosomal small subunit assembly [PMID:9271380]
experiment: EXISTENCE:mutant phenotype:GO:0006364 rRNA processing [PMID:9271380]
note: Essential protein involved in rRNA processing and ribosome biogenesis; forms a complex with Utp22p; protein abundance increases in response to DNA replication stress
codon start: 1
product: Rrp7p
translation: MGIEDISAMKNGFIVVPFKLPDHKALPKSQEASLHFMFAKRHQSSNSNESDCLFLVNLPLLSNIEHMKKFVGQLCGKYDTVSHVEELLYNDEFGLHEVDLSALTSDLMSSTDVNEKRYTPRNTALLKFVDAASINNCWNALKKYSNLHAKHPNELFEWTYTTPSFTTFVNFYKPLDIDYLKEDIHTHMAIFEQREAQAQEDVQSSIVDEDGFTLVVGKNTKSLNSIRKKILNKNPLSKHENKAKPISNIDKKAKKDFYRFQVRERKKQEINQLLSKFKEDQERIKVMKAKRKFNPYT
SIO_010081: YCL031C
subclass of: SO_0000673
so part of: YCL031C
location: complement(64675..65568)
location: region:64675-65568:-1
so has part: feature:64675-65568:-1:exon

NP_009899.1
type: Protein
SIO_000068: ncbiprotein

S000000536
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:64675-65568:-1:exon

YCL030C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HIS4
locus tag: YCL030C
so part of: sequence
location: complement(<65934..>68333)
location: region:65934-68333:-1
so has part: feature:65934-68333:-1:exon
subclass of: SO_0000010

850327
type: Gene
SIO_000068: ncbigene

position:65934:-1
position: 65934
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:68333:-1
position: 68333
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:65934-68333:-1:exon

YCL030C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HIS4
locus tag: YCL030C
product: trifunctional histidinol dehydrogenase/phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase
transcript id: NM_001178675.1
SIO_010081: YCL030C
subclass of: SO_0000673
so part of: YCL030C
location: complement(<65934..>68333)
location: region:65934-68333:-1
so has part: feature:65934-68333:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:65934-68333:-1:exon

YCL030C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: HIS4
locus tag: YCL030C
EC number: 1.1.1.23
EC number: 3.5.4.19
EC number: 3.6.1.31
experiment: EXISTENCE:direct assay:GO:0004399 histidinol dehydrogenase activity [PMID:379004]
experiment: EXISTENCE:direct assay:GO:0004635 phosphoribosyl-AMP cyclohydrolase activity [PMID:379004]
experiment: EXISTENCE:direct assay:GO:0004636 phosphoribosyl-ATP diphosphatase activity [PMID:379004]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0000105 histidine biosynthetic process [PMID:5919326|PMID:14190241]
experiment: EXISTENCE:mutant phenotype:GO:0004399 histidinol dehydrogenase activity [PMID:5919326]
experiment: EXISTENCE:mutant phenotype:GO:0004635 phosphoribosyl-AMP cyclohydrolase activity [PMID:5919326]
experiment: EXISTENCE:mutant phenotype:GO:0004636 phosphoribosyl-ATP diphosphatase activity [PMID:5919326]
note: Multifunctional enzyme containing phosphoribosyl-ATP pyrophosphatase; phosphoribosyl-AMP cyclohydrolase, and histidinol dehydrogenase activities; catalyzes the second, third, ninth and tenth steps in histidine biosynthesis
codon start: 1
product: trifunctional histidinol dehydrogenase/phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase
translation: MVLPILPLIDDLASWNSKKEYVSLVGQVLLDGSSLSNEEILQFSKEEEVPLVALSLPSGKFSDDEIIAFLNNGVSSLFIASQDAKTAEHLVEQLNVPKERVVVEENGVFSNQFMVKQKFSQDKIVSIKKLSKDMLTKEVLGEVRTDRPDGLYTTLVVDQYERCLGLVYSSKKSIAKAIDLGRGVYYSRSRNEIWIKGETSGNGQKLLQISTDCDSDALKFIVEQENVGFCHLETMSCFGEFKHGLVGLESLLKQRLQDAPEESYTRRLFNDSALLDAKIKEEAEELTEAKGKKELSWEAADLFYFALAKLVANDVSLKDVENNLNMKHLKVTRRKGDAKPKFVGQPKAEEEKLTGPIHLDVVKASDKVGVQKALSRPIQKTSEIMHLVNPIIENVRDKGNSALLEYTEKFDGVKLSNPVLNAPFPEEYFEGLTEEMKEALDLSIENVRKFHAAQLPTETLEVETQPGVLCSRFPRPIEKVGLYIPGGTAILPSTALMLGVPAQVAQCKEIVFASPPRKSDGKVSPEVVYVAEKVGASKIVLAGGAQAVAAMAYGTETIPKVDKILGPGNQFVTAAKMYVQNDTQALCSIDMPAGPSEVLVIADEDADVDFVASDLLSQAEHGIDSQVILVGVNLSEKKIQEIQDAVHNQALQLPRVDIVRKCIAHSTIVLCDGYEEALEMSNQYAPEHLILQIANANDYVKLVDNAGSVFVGAYTPESCGDYSSGTNHTLPTYGYARQYSGANTATFQKFITAQNITPEGLENIGRAVMCVAKKEGLDGHRNAVKIRMSKLGLIPKDFQ
SIO_010081: YCL030C
subclass of: SO_0000673
so part of: YCL030C
location: complement(65934..68333)
location: region:65934-68333:-1
so has part: feature:65934-68333:-1:exon

NP_009900.2
type: Protein
SIO_000068: ncbiprotein

S000000535
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:65934-68333:-1:exon

YCL029C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ARM5
alternative label: PAC14
gene: BIK1
locus tag: YCL029C
gene synonym: ARM5; PAC14
so part of: sequence
location: complement(<68599..>69921)
location: region:68599-69921:-1
so has part: feature:68599-69921:-1:exon
subclass of: SO_0000010

850328
type: Gene
SIO_000068: ncbigene

position:68599:-1
position: 68599
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:69921:-1
position: 69921
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:68599-69921:-1:exon

YCL029C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ARM5
alternative label: PAC14
gene: BIK1
locus tag: YCL029C
gene synonym: ARM5; PAC14
product: Bik1p
transcript id: NM_001178674.1
SIO_010081: YCL029C
subclass of: SO_0000673
so part of: YCL029C
location: complement(<68599..>69921)
location: region:68599-69921:-1
so has part: feature:68599-69921:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:68599-69921:-1:exon

YCL029C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ARM5
alternative label: PAC14
gene: BIK1
locus tag: YCL029C
gene synonym: ARM5; PAC14
experiment: EXISTENCE:direct assay:GO:0000776 kinetochore [PMID:11756471|PMID:35235370|PMID:11511347]
experiment: EXISTENCE:direct assay:GO:0005816 spindle pole body [PMID:2277073]
experiment: EXISTENCE:direct assay:GO:0005819 spindle [PMID:2277073]
experiment: EXISTENCE:direct assay:GO:0005876 spindle microtubule [PMID:11511347]
experiment: EXISTENCE:direct assay:GO:0005938 cell cortex [PMID:11511347]
experiment: EXISTENCE:direct assay:GO:0008017 microtubule binding [PMID:9398684]
experiment: EXISTENCE:direct assay:GO:0019894 kinesin binding [PMID:35235370]
experiment: EXISTENCE:direct assay:GO:0031115 negative regulation of microtubule polymerization [PMID:20392838]
experiment: EXISTENCE:direct assay:GO:0035371 microtubule plus-end [PMID:20392838]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:16380440]
experiment: EXISTENCE:genetic interaction:GO:0000022 mitotic spindle elongation [PMID:7559759]
experiment: EXISTENCE:genetic interaction:GO:0030543 2-micrometer plasmid partitioning [PMID:28004422]
experiment: EXISTENCE:mutant phenotype:GO:0000742 karyogamy involved in conjugation with cellular fusion [PMID:2277073]
experiment: EXISTENCE:mutant phenotype:GO:0000743 nuclear migration involved in conjugation with cellular fusion [PMID:16380440]
experiment: EXISTENCE:mutant phenotype:GO:0000819 sister chromatid segregation [PMID:35235370]
experiment: EXISTENCE:mutant phenotype:GO:0007020 microtubule nucleation [PMID:33752231]
experiment: EXISTENCE:mutant phenotype:GO:0030543 2-micrometer plasmid partitioning [PMID:28004422]
note: Microtubule-associated protein; component of the interface between microtubules and kinetochore, involved in sister chromatid separation; essential in polyploid cells but not in haploid or diploid cells; promotes plus-end directed movement of Dyn1p; ortholog of mammalian CLIP-170
codon start: 1
product: Bik1p
translation: MDRYQRKIGCFIQIPNLGRGQLKYVGPVDTKAGMFAGVDLLANIGKNDGSFMGKKYFQTEYPQSGLFIQLQKVASLIEKASISQTSRRTTMEPLSIPKNRSIVRLTNQFSPMDDPKSPTPMRSFRITSRHSGNQQSMDQEASDHHQQQEFGYDNREDRMEVDSILSSDRKANHNTTSDWKPDNGHMNDLNSSEVTIELREAQLTIEKLQRKQLHYKRLLDDQRMVLEEVQPTFDRYEATIQEREKEIDHLKQQLELERRQQAKQKQFFDAENEQLLAVVSQLHEEIKENEERNLSHNQPTGANEDVELLKKQLEQLRNIEDQFELHKTKWAKEREQLKMHNDSLSKEYQNLSKELFLTKPQDSSSEEVASLTKKLEEANEKIKQLEQAQAQTAVESLPIFDPPAPVDTTAGRQQWCEHCDTMGHNTAECPHHNPDNQQFF
SIO_010081: YCL029C
subclass of: SO_0000673
so part of: YCL029C
location: complement(68599..69921)
location: region:68599-69921:-1
so has part: feature:68599-69921:-1:exon

NP_009901.1
type: Protein
SIO_000068: ncbiprotein

S000000534
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:68599-69921:-1:exon

YCL028W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RNQ1
locus tag: YCL028W
so part of: sequence
location: <70150..>71367
location: region:70150-71367:1
so has part: feature:70150-71367:1:exon
subclass of: SO_0000010

850329
type: Gene
SIO_000068: ncbigene

position:70150:1
position: 70150
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:71367:1
position: 71367
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:70150-71367:1:exon

YCL028W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RNQ1
locus tag: YCL028W
product: prion domain-containing protein RNQ1
transcript id: NM_001178673.1
SIO_010081: YCL028W
subclass of: SO_0000673
so part of: YCL028W
location: <70150..>71367
location: region:70150-71367:1
so has part: feature:70150-71367:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:70150-71367:1:exon

YCL028W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RNQ1
locus tag: YCL028W
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:11511345]
note: [PIN(+)] prion, named for [PSI+] INducibility; an infectious protein conformation that is generally an ordered protein aggregate
codon start: 1
product: prion domain-containing protein RNQ1
translation: MDTDKLISEAESHFSQGNHAEAVAKLTSAAQSNPNDEQMSTIESLIQKIAGYVMDNRSGGSDASQDRAAGGGSSFMNTLMADSKGSSQTQLGKLALLATVMTHSSNKGSSNRGFDVGTVMSMLSGSGGGSQSMGASGLAALASQFFKSGNNSQGQGQGQGQGQGQGQGQGQGSFTALASLASSFMNSNNNNQQGQNQSSGGSSFGALASMASSFMHSNNNQNSNNSQQGYNQSYQNGNQNSQGYNNQQYQGGNGGYQQQQGQSGGAFSSLASMAQSYLGGGQTQSNQQQYNQQGQNNQQQYQQQGQNYQHQQQGQQQQQGHSSSFSALASMASSYLGNNSNSNSSYGGQQQANEYGRPQQNGQQQSNEYGRPQYGGNQNSNGQHESFNFSGNFSQQNNNGNQNRY
SIO_010081: YCL028W
subclass of: SO_0000673
so part of: YCL028W
location: 70150..71367
location: region:70150-71367:1
so has part: feature:70150-71367:1:exon

NP_009902.2
type: Protein
SIO_000068: ncbiprotein

S000000533
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:70150-71367:1:exon

YCL027W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FUS1
locus tag: YCL027W
so part of: sequence
location: <71803..>73341
location: region:71803-73341:1
so has part: feature:71803-73341:1:exon
subclass of: SO_0000010

850330
type: Gene
SIO_000068: ncbigene

position:71803:1
position: 71803
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:73341:1
position: 73341
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:71803-73341:1:exon

YCL027W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FUS1
locus tag: YCL027W
product: Fus1p
transcript id: NM_001178672.1
SIO_010081: YCL027W
subclass of: SO_0000673
so part of: YCL027W
location: <71803..>73341
location: region:71803-73341:1
so has part: feature:71803-73341:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:71803-73341:1:exon

YCL027W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FUS1
locus tag: YCL027W
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:2690078]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:12374868|PMID:3302672|PMID:19053807]
experiment: EXISTENCE:genetic interaction:GO:0000755 cytogamy [PMID:3302672]
experiment: EXISTENCE:mutant phenotype:GO:0000755 cytogamy [PMID:3313002|PMID:3302672]
experiment: EXISTENCE:mutant phenotype:GO:0031385 regulation of termination of mating projection growth [PMID:14734532]
experiment: EXISTENCE:mutant phenotype:GO:0032065 maintenance of protein location in cell cortex [PMID:18474625]
note: Membrane protein localized to the shmoo tip; required for cell fusion; expression regulated by mating pheromone; proposed to coordinate signaling, fusion, and polarization events required for fusion; potential Cdc28p substrate
codon start: 1
product: Fus1p
translation: MVATIMQTTTTVLTTVAAMSTTLASNYISSQASSSTSVTTVTTIATSIRSTPSNLLFSNVAAQPKSSSASTIGLSIGLPIGIFCFGLLILLCYFYLKRNSVSISNPPMSATIPREEEYCRRTNWFSRLFWQSKCEDQNSYSNRDIEKYNDTQWTSGDNMSSKIQYKISKPIIPQHILTPKKTVKNPYAWSGKNISLDPKVNEMEEEKVVDAFLYTKPPNIVHIESSMPSYNDLPSQKTVSSKKTALKTSEKWSYESPLSRWFLRGSTYFKDYGLSKTSLKTPTGAPQLKQMKMLSRISKGYFNESDIMPDERSPILEYNNTPLDANDSVNNLGNTTPDSQITSYRNNNIDLITARPHSVIYGTTAQQTLETNFNDHHDCNKSTEKHELIIPTPSKPLKKRKKRRQSKMYQHLQHLSRSKPLPLTPNSKYNGEASVQLGKTYTVIQDYEPRLTDEIRISLGEKVKILATHTDGWCLVEKCNTQKGSIHVSVDDKRYLNEDRGIVPGDCLQEYD
SIO_010081: YCL027W
subclass of: SO_0000673
so part of: YCL027W
location: 71803..73341
location: region:71803-73341:1
so has part: feature:71803-73341:1:exon

NP_009903.2
type: Protein
SIO_000068: ncbiprotein

S000000532
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:71803-73341:1:exon

YCL026C-B
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YCL027C-A
gene: HBN1
locus tag: YCL026C-B
gene synonym: YCL027C-A
so part of: sequence
location: complement(<73405..>73986)
location: region:73405-73986:-1
so has part: feature:73405-73986:-1:exon
subclass of: SO_0000010

850331
type: Gene
SIO_000068: ncbigene

position:73405:-1
position: 73405
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:73986:-1
position: 73986
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:73405-73986:-1:exon

YCL026C-B
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YCL027C-A
gene: HBN1
locus tag: YCL026C-B
gene synonym: YCL027C-A
product: putative nitroreductase
transcript id: NM_001184449.1
SIO_010081: YCL026C-B
subclass of: SO_0000673
so part of: YCL026C-B
location: complement(<73405..>73986)
location: region:73405-73986:-1
so has part: feature:73405-73986:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:73405-73986:-1:exon

YCL026C-B
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YCL027C-A
gene: HBN1
locus tag: YCL026C-B
gene synonym: YCL027C-A
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
note: hypothetical protein; similar to bacterial nitroreductases; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; protein becomes insoluble upon intracellular iron depletion; protein abundance increases in response to DNA replication stress
codon start: 1
product: putative nitroreductase
translation: MSAVATYLKTLTARRTIYALKPELPGEITINDIQSVVQTIIKETPTAFNSQPNRAVILTGETHKKVWDEVTKAIESPAGQKRPASARDEAFGSVIFFTDDKVTEKLKADFPAYAAAFPSFADHTSGAAQINSWVALEAMGLGGHLQHYNGYIKAALPSKIPESWTVQAQLVFGTPAAPPGEKTYIKNDVEIFN
SIO_010081: YCL026C-B
subclass of: SO_0000673
so part of: YCL026C-B
location: complement(73405..73986)
location: region:73405-73986:-1
so has part: feature:73405-73986:-1:exon

NP_065436.1
type: Protein
SIO_000068: ncbiprotein

S000007548
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:73405-73986:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS306; Early-firing autonomously replicating sequence on Chromosome III
so part of: sequence
location: 74458..74677
location: region:74458-74677:1
so has part: feature:74458-74677:1:region

S000028483
type: SGD
SIO_000068: sgd

position:74458:1
position: 74458
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:74677:1
position: 74677
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:74458-74677:1:region

YCL026C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YCLX08C
gene: FRM2
locus tag: YCL026C-A
gene synonym: YCLX08C
so part of: sequence
location: complement(<74704..>75285)
location: region:74704-75285:-1
so has part: feature:74704-75285:-1:exon
subclass of: SO_0000010

850332
type: Gene
SIO_000068: ncbigene

position:74704:-1
position: 74704
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:75285:-1
position: 75285
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:74704-75285:-1:exon

YCL026C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YCLX08C
gene: FRM2
locus tag: YCL026C-A
gene synonym: YCLX08C
product: type II nitroreductase
transcript id: NM_001178713.1
SIO_010081: YCL026C-A
subclass of: SO_0000673
so part of: YCL026C-A
location: complement(<74704..>75285)
location: region:74704-75285:-1
so has part: feature:74704-75285:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:74704-75285:-1:exon

YCL026C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YCLX08C
gene: FRM2
locus tag: YCL026C-A
gene synonym: YCLX08C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0016657 oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor [PMID:22687599]
experiment: EXISTENCE:genetic interaction:GO:0034599 cellular response to oxidative stress [PMID:19904831]
experiment: EXISTENCE:mutant phenotype:GO:0034599 cellular response to oxidative stress [PMID:19904831]
experiment: EXISTENCE:mutant phenotype:GO:0045922 negative regulation of fatty acid metabolic process [PMID:8701605]
note: Type II nitroreductase, using NADH as reductant; mutants are defective in fatty acid mediated repression of genes involved in fatty acid biosynthesis indicative of a role in lipid signaling; involved in the oxidative stress response; transcription induction by cadmium and selenite indicates a possible role in the metal stress response; expression induced in cells treated with the mycotoxin patulin
codon start: 1
product: type II nitroreductase
translation: MSPTGNYLNAITNRRTIYNLKPELPQGVGLDDVKRTVHVILKNTPTAFNSQVNRAVIIVGDTHKRIWDAVASAMPTAEAKKRPESCRDEAYGSVIFFTDEGPTEKLQRDFPALAAAFPTCAAHTTGAVQIQSWTALELLGLGANLQHYNDYVKSALPQDVPIAWTVQSQLVFGVPTALPEEKTFINNVINVYH
SIO_010081: YCL026C-A
subclass of: SO_0000673
so part of: YCL026C-A
location: complement(74704..75285)
location: region:74704-75285:-1
so has part: feature:74704-75285:-1:exon

NP_009904.2
type: Protein
SIO_000068: ncbiprotein

S000000589
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:74704-75285:-1:exon

YCL025C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: WAP1
alternative label: YCC5
gene: AGP1
locus tag: YCL025C
gene synonym: WAP1; YCC5
so part of: sequence
location: complement(<76018..>77919)
location: region:76018-77919:-1
so has part: feature:76018-77919:-1:exon
subclass of: SO_0000010

850333
type: Gene
SIO_000068: ncbigene

position:76018:-1
position: 76018
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:77919:-1
position: 77919
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:76018-77919:-1:exon

YCL025C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: WAP1
alternative label: YCC5
gene: AGP1
locus tag: YCL025C
gene synonym: WAP1; YCC5
product: amino acid transporter AGP1
transcript id: NM_001178671.1
SIO_010081: YCL025C
subclass of: SO_0000673
so part of: YCL025C
location: complement(<76018..>77919)
location: region:76018-77919:-1
so has part: feature:76018-77919:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:76018-77919:-1:exon

YCL025C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: WAP1
alternative label: YCC5
gene: AGP1
locus tag: YCL025C
gene synonym: WAP1; YCC5
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:27226538]
experiment: EXISTENCE:direct assay:GO:0006865 amino acid transport [PMID:10654085]
experiment: EXISTENCE:direct assay:GO:0015171 amino acid transmembrane transporter activity [PMID:10654085]
experiment: EXISTENCE:direct assay:GO:0055085 transmembrane transport [PMID:10654085]
experiment: EXISTENCE:genetic interaction:GO:0015193 L-proline transmembrane transporter activity [PMID:14968425]
experiment: EXISTENCE:genetic interaction:GO:0098718 serine import across plasma membrane [PMID:32845888]
experiment: EXISTENCE:mutant phenotype:GO:0098718 serine import across plasma membrane [PMID:32845888]
note: Broad-specificity, low-affinity amino acid permease; minor serine permease with major contributions from paralog Gnp1p; involved in uptake of asparagine, glutamine, and other amino acids; expression induced by amino acids and regulated by SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p)
codon start: 1
product: amino acid transporter AGP1
translation: MSSSKSLYELKDLKNSSTEIHATGQDNEIEYFETGSNDRPSSQPHLGYEQHNTSAVRRFFDSFKRADQGPQDEVEATQMNDLTSAISPSSRQAQELEKNESSDNIGANTGHKSDSLKKTIQPRHVLMIALGTGIGTGLLVGNGTALVHAGPAGLLIGYAIMGSILYCIIQACGEMALVYSNLTGGYNAYPSFLVDDGFGFAVAWVYCLQWLCVCPLELVTASMTIKYWTTSVNPDVFVIIFYVLVITINIFGARGYAEAEFFFNCCKILMMTGFFILGIIIDVGGAGNDGFIGGKYWHDPGAFNGKHAIDRFKGVAATLVTAAFAFGGSEFIAITTAEQSNPRKAIPGAAKQMIYRILFLFLATIILLGFLVPYNSDQLLGSTGGGTKASPYVIAVASHGVRVVPHFINAVILLSVLSMANSSFYSSARLFLTLSEQGYAPKVFSYIDRAGRPLIAMGVSALFAVIAFCAASPKEEQVFTWLLAISGLSQLFTWTAICLSHLRFRRAMKVQGRSLGELGFKSQTGVWGSAYACIMMILILIAQFWVAIAPIGEGKLDAQAFFENYLAMPILIALYVGYKVWHKDWKLFIRADKIDLDSHRQIFDEELIKQEDEEYRERLRNGPYWKRVVAFWC
SIO_010081: YCL025C
subclass of: SO_0000673
so part of: YCL025C
location: complement(76018..77919)
location: region:76018-77919:-1
so has part: feature:76018-77919:-1:exon

NP_009905.3
type: Protein
SIO_000068: ncbiprotein

S000000530
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:76018-77919:-1:exon

YCL024W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: KCC4
locus tag: YCL024W
so part of: sequence
location: <79162..>82275
location: region:79162-82275:1
so has part: feature:79162-82275:1:exon
subclass of: SO_0000010

850334
type: Gene
SIO_000068: ncbigene

position:79162:1
position: 79162
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:82275:1
position: 82275
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:79162-82275:1:exon

YCL024W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: KCC4
locus tag: YCL024W
product: serine/threonine protein kinase
transcript id: NM_001178670.1
SIO_010081: YCL024W
subclass of: SO_0000673
so part of: YCL024W
location: <79162..>82275
location: region:79162-82275:1
so has part: feature:79162-82275:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:79162-82275:1:exon

YCL024W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: KCC4
locus tag: YCL024W
EC number: 2.7.11.1
experiment: EXISTENCE:direct assay:GO:0000131 incipient cellular bud site [PMID:15901837]
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:16319894]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:15282802|PMID:9925642]
experiment: EXISTENCE:direct assay:GO:0005940 septin ring [PMID:15901837]
experiment: EXISTENCE:direct assay:GO:0006468 protein phosphorylation [PMID:16319894]
experiment: EXISTENCE:direct assay:GO:0032174 cellular bud neck septin collar [PMID:15901837]
experiment: EXISTENCE:mutant phenotype:GO:0000921 septin ring assembly [PMID:9925642]
experiment: EXISTENCE:mutant phenotype:GO:0007117 budding cell bud growth [PMID:9925642]
experiment: EXISTENCE:mutant phenotype:GO:0044879 mitotic morphogenesis checkpoint signaling [PMID:9925642]
note: Protein kinase of the bud neck involved in the septin checkpoint; associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p; KCC4 has a paralog, GIN4, that arose from the whole genome duplication
codon start: 1
product: serine/threonine protein kinase
translation: MTVANTETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKSIKDLPRENTYLYPLADSNNHTSASIDDSILQNLVVLWHGRHADDIVSKLKENGTNKEKILYALLYRFKLDSVRGSNKKNRNKIKKTKKNKRSSTLSSSSSLLLNNRSIQSTPRRRTSKRHSREFSSSRKRSSFLLSSNPTDSSPIPLRSSKRITHINVASANTQATPSGVPNPHKRNSKKRSSKRLSYMPNTKRSSLTSKSLSNFTNLIDDDDWEYIEKDAKRTSSNFATLIDEIFEPEKFELAKREKAELQRKVQEAKRQSVNAQKINEDEFGSEVSDGMKELKKINDKVSSPLINYEFSQQELLQDIDTLLTNRYQLSSYTRPISRLDPGLTPVTETLPNNLKEKTALLQDTEKKIIETIRRSKFLGSLLNVRGGLSPGKSELAPIEESPIVSTTPLIYNDRMEPRRISDVEVPHFTRKSKHFTTANNRRSVLSLYAKDSIKDLNEFLIKEDPDLPPQGSTDNESRSEDPEIAESITDSRNIQYDEDDSKDGDNVNNDNILSDFPQGVGISQEYDMKDKNPNQSPISKSAEPTLVVKLPSLSSFQGKNASGLGLYQREPSKVTLPSLTSNNSSVGENIEDGAEKGTESEKIAASLSDDDLKEDNDKKDNDTVNAPTTVKKPPNSVLLKKFSKGKILELEIHAKIPEKRLYEGLHKLLEGWKQYGLKNLVFNITNMIITGKLVNDSILFLRSTLFEIMVLPNGDGRSLIKFNKKTGSTKTLTKLATEIQIILQKEGVLDK
SIO_010081: YCL024W
subclass of: SO_0000673
so part of: YCL024W
location: 79162..82275
location: region:79162-82275:1
so has part: feature:79162-82275:1:exon

NP_009907.2
type: Protein
SIO_000068: ncbiprotein

S000000529
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:79162-82275:1:exon

YNCC0001C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCC0001C
so part of: sequence
location: complement(82462..82533)
location: region:82462-82533:-1
so has part: feature:82462-82533:-1:exon
subclass of: SO_0000663

850337
type: Gene
SIO_000068: ncbigene

position:82462:-1
position: 82462
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:82533:-1
position: 82533
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:82462-82533:-1:exon

YNCC0001C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCC0001C
product: tRNA-Glu
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Glutamine tRNA (tRNA-Glu), predicted by tRNAscan-SE analysis; thiolation of uridine at wobble position (34) requires Ncs6p
SIO_010081: YNCC0001C
subclass of: SO_0000673
so part of: YNCC0001C
location: complement(82462..82533)
location: region:82462-82533:-1
so has part: feature:82462-82533:-1:exon

S000006549
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:82462-82533:-1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 82700..83036
location: region:82700-83036:1
so has part: feature:82700-83036:1:region

S000126593
type: SGD
SIO_000068: sgd

position:82700:1
position: 82700
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:83036:1
position: 83036
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:82700-83036:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(83055..83194)
location: region:83055-83194:-1
so has part: feature:83055-83194:-1:region

S000006822
type: SGD
SIO_000068: sgd

position:83055:-1
position: 83055
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:83194:-1
position: 83194
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:83055-83194:-1:region

YCL021W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCL021W-A
so part of: sequence
location: <83620..>83997
location: region:83620-83997:1
so has part: feature:83620-83997:1:exon
subclass of: SO_0000010

850338
type: Gene
SIO_000068: ncbigene

position:83620:1
position: 83620
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:83997:1
position: 83997
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:83620-83997:1:exon

YCL021W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCL021W-A
product: uncharacterized protein
transcript id: NM_001184450.1
SIO_010081: YCL021W-A
subclass of: SO_0000673
so part of: YCL021W-A
location: <83620..>83997
location: region:83620-83997:1
so has part: feature:83620-83997:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:83620-83997:1:exon

YCL021W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YCL021W-A
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
note: hypothetical protein; SWAT-GFP and mCherry fusion proteins localize to the vacuole
codon start: 1
product: uncharacterized protein
translation: MVLTDAEELRSPVITSDMSFFDLESNHSSDSVHLLCEKYTHKLPIESESQTTFRLAPTKQRLYRQSTLYVPLSLKQRVFLFTERVKSIWAGLPRCKPNKYFKVAFALAVLTPLAIWIFYIDFRVH
SIO_010081: YCL021W-A
subclass of: SO_0000673
so part of: YCL021W-A
location: 83620..83997
location: region:83620-83997:1
so has part: feature:83620-83997:1:exon

NP_065437.1
type: Protein
SIO_000068: ncbiprotein

S000007549
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:83620-83997:1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 84069..84294
location: region:84069-84294:1
so has part: feature:84069-84294:1:region

S000006823
type: SGD
SIO_000068: sgd

position:84069:1
position: 84069
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:84294:1
position: 84294
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:84069-84294:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 84295..84626
location: region:84295-84626:1
so has part: feature:84295-84626:1:region

S000006825
type: SGD
SIO_000068: sgd

position:84295:1
position: 84295
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:84626:1
position: 84626
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:84295-84626:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 84630..84718
location: region:84630-84718:1
so has part: feature:84630-84718:1:region

S000006824
type: SGD
SIO_000068: sgd

position:84630:1
position: 84630
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:84718:1
position: 84718
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:84630-84718:1:region

mobile_element
type: Mobile Element
subclass of: SO_0001037
RO_0002162: 559292
note: YCLWTy2-1; Ty2 element, LTR retrotransposon of the Copia (Pseudoviridae) group; contains co-transcribed genes TYA Gag and TYB Pol, encoding proteins involved in structure and function of virus-like particles, flanked by two direct repeats
mobile element type: retrotransposon:YCLWTy2-1
so part of: sequence
location: 84811..90769
location: region:84811-90769:1
so has part: feature:84811-90769:1:region

S000006830
type: SGD
SIO_000068: sgd

position:84811:1
position: 84811
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:90769:1
position: 90769
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:84811-90769:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty2 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 84811..85142
location: region:84811-85142:1
so has part: feature:84811-85142:1:region

S000006826
type: SGD
SIO_000068: sgd

position:85142:1
position: 85142
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:84811-85142:1:region

YCL019W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCL019W
so part of: sequence
location: <85102..>90415
location: region:85102-90415:1
so has part: feature:85102-90415:1:exon
subclass of: SO_0000010

850340
type: Gene
SIO_000068: ncbigene

position:85102:1
position: 85102
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:90415:1
position: 90415
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:85102-90415:1:exon

YCL019W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCL019W
product: gag-pol fusion protein
transcript id: NM_001178666.2
SIO_010081: YCL019W
subclass of: SO_0000673
so part of: YCL019W
location: <85102..>90415
location: region:85102-90415:1
so has part: feature:85102-90415:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:85102-90415:1:exon

YCL019W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YCL019W
EC number: 2.7.7.7
EC number: 2.7.7.49
EC number: 3.1.26.4
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:9448009]
ribosomal slippage: true
note: Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes
codon start: 1
product: gag-pol fusion protein
translation: MESQQLHQNPRSLHGSAYASVTSKEVPSNQDPLAVSASNLPEFDRDSTKVNSQQETTPGTSAVPENHHHVSPQPASVPPPQNGQYQQHGMMTPNKAMASNWAHYQQPSMMTCSHYQTSPAYYQPDPHYPLPQYIPPLSTSSPDPIDSQNQHSEVPQAETKVRNNVLPPHTLTSEENFSTWVKFYIRFLKNSNLGDIIPNDQGEIKRQMTYEEHAYIYNTFQAFAPFHLLPTWVKQILEINYADILTVLCKSVSKMQTNNQELKDWIALANLEYDGSTSADTFEITVSTIIQRLKENNINVSDRLACQLILKGLSGDFKYLRNQYRTKTNMKLSQLFAEIQLIYDENKIMNLNKPSQYKQHSEYKNVSRTSPNTTNTKVTTRNYQRTNSSKPRAAKAHNIATSSKFSRVNNDHINESTVSSQYLSDDNELSLGQQQKESKPTHTIDSNDELPDHLLIDSGASQTLVRSAHYLHHATPNSEINIVDAQKQDIPINAIGNLHFNFQNGTKTSIKALHTPNIAYDLLSLSELANQNITACFTRNTLERSDGTVLAPIVKHGDFYWLSKKYLIPSHISKLTINNVNKSKSVNKYPYPLIHRMLGHANFRSIQKSLKKNAVTYLKESDIEWSNASTYQCPDCLIGKSTKHRHVKGSRLKYQESYEPFQYLHTDIFGPVHHLPKSAPSYFISFTDEKTRFQWVYPLHDRREESILNVFTSILAFIKNQFNARVLVIQMDRGSEYTNKTLHKFFTNRGITACYTTTADSRAHGVAERLNRTLLNDCRTLLHCSGLPNHLWFSAVEFSTIIRNSLVSPKNDKSARQHAGLAGLDITTILPFGQPVIVNNHNPDSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQDKQSKLDQFNYDTLTFDDDLNRLTAHNQSFIEQNETEQSYDQNTESDHDYQSEIEINSDPLVNDFSSQSINPLQLDKEPVQKVRAPKEVDADISEYNILPSPVRSRTPHIINKESTEMGGTVESDTTSPRHSSTFTARNQKRPGSPNDMIDLTSQDRVNYGLENIKTTRLGGTEEPYIQRNSDTNIKYRTTNSTPSIDDRSSNSESTTPIISIETKAVCDNTPSIDTDPPEYRSSDHATPNIMPDKSSKNVTADSILDDLPLPDLTHQSPTDTSDVSKDIPHIHSRQTNSSLGGMDDSNVLTTTKSKKRSLEDNETEIEVSRDTWNNKNMRSLEPPRSKKRINLIAAIKGVKSIKPVRTTLRYDEAITYNKDNKEKDRYVEAYHKEISQLLKMNTWDTNKYYDRNDIDPKKVINSMFIFNKKRDGTHKARFVARGDIQHPDTYDSDMQSNTVHHYALMTSLSIALDNDYYITQLDISSAYLYADIKEELYIRPPPHLGLNDKLLRLRKSLYGLKQSGANWYETIKSYLINCCDMQEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRSKYMKLGMEKSLTEKLPKLNVPLNPKGKKLRAPGQPGHYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTKPDNKLVAISDASYGNQPYYKSQIGNIFLLNGKVIGGKSTKASLTCTSTTEAEIHAVSEAIPLLNNLSHLVQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYYIETKKNIADVMTKPLPIKTFKLLTNKWIH
SIO_010081: YCL019W
subclass of: SO_0000673
so part of: YCL019W
location: join(85102..86391,86393..90415)
location: region:85102-90415:1
so has part: feature:85102-86391:1:exon
so has part: feature:86393-90415:1:exon

NP_009909.2
type: Protein
SIO_000068: ncbiprotein

S000000524
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:85102-86391:1:exon

position:86391:1
position: 86391
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:86393-90415:1:exon

position:86393:1
position: 86393
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YCL020W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCL020W
so part of: sequence
location: <85102..>86418
location: region:85102-86418:1
so has part: feature:85102-86418:1:exon
subclass of: SO_0000010

850339
type: Gene
SIO_000068: ncbigene

position:86418:1
position: 86418
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:85102-86418:1:exon

YCL020W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCL020W
product: gag protein
transcript id: NM_001178667.1
SIO_010081: YCL020W
subclass of: SO_0000673
so part of: YCL020W
location: <85102..>86418
location: region:85102-86418:1
so has part: feature:85102-86418:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:85102-86418:1:exon

YCL020W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YCL020W
note: Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag
codon start: 1
product: gag protein
translation: MESQQLHQNPRSLHGSAYASVTSKEVPSNQDPLAVSASNLPEFDRDSTKVNSQQETTPGTSAVPENHHHVSPQPASVPPPQNGQYQQHGMMTPNKAMASNWAHYQQPSMMTCSHYQTSPAYYQPDPHYPLPQYIPPLSTSSPDPIDSQNQHSEVPQAETKVRNNVLPPHTLTSEENFSTWVKFYIRFLKNSNLGDIIPNDQGEIKRQMTYEEHAYIYNTFQAFAPFHLLPTWVKQILEINYADILTVLCKSVSKMQTNNQELKDWIALANLEYDGSTSADTFEITVSTIIQRLKENNINVSDRLACQLILKGLSGDFKYLRNQYRTKTNMKLSQLFAEIQLIYDENKIMNLNKPSQYKQHSEYKNVSRTSPNTTNTKVTTRNYQRTNSSKPRAAKAHNIATSSKFSRVNNDHINESTVSSQYLSDDNELSLRPATERI
SIO_010081: YCL020W
subclass of: SO_0000673
so part of: YCL020W
location: 85102..86418
location: region:85102-86418:1
so has part: feature:85102-86418:1:exon

NP_009910.2
type: Protein
SIO_000068: ncbiprotein

S000000525
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:85102-86418:1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty2 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 90438..90769
location: region:90438-90769:1
so has part: feature:90438-90769:1:region

S000006827
type: SGD
SIO_000068: sgd

position:90438:1
position: 90438
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:90438-90769:1:region

YNCC0002W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SUP53
locus tag: YNCC0002W
so part of: sequence
location: 90859..90972
location: region:90859-90972:1
so has part: feature:90859-90972:1:exon
subclass of: SO_0000663

850341
type: Gene
SIO_000068: ncbigene

position:90859:1
position: 90859
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:90972:1
position: 90972
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:90859-90972:1:exon

YNCC0002W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
gene: SUP53
locus tag: YNCC0002W
product: tRNA-Leu
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Leucine tRNA (tRNA-Leu), predicted by tRNAscan-SE analysis; can mutate to suppress amber nonsense mutations
SIO_010081: YNCC0002W
subclass of: SO_0000673
so part of: YNCC0002W
location: join(90859..90896,90929..90972)
location: region:90859-90972:1
so has part: feature:90859-90896:1:exon
so has part: feature:90929-90972:1:exon

S000006637
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:90859-90896:1:exon

position:90896:1
position: 90896
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:90929-90972:1:exon

position:90929:1
position: 90929
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YCL018W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: LEU2
locus tag: YCL018W
so part of: sequence
location: <91324..>92418
location: region:91324-92418:1
so has part: feature:91324-92418:1:exon
subclass of: SO_0000010

850342
type: Gene
SIO_000068: ncbigene

position:91324:1
position: 91324
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:92418:1
position: 92418
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:91324-92418:1:exon

YCL018W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: LEU2
locus tag: YCL018W
product: 3-isopropylmalate dehydrogenase
transcript id: NM_001178665.1
SIO_010081: YCL018W
subclass of: SO_0000673
so part of: YCL018W
location: <91324..>92418
location: region:91324-92418:1
so has part: feature:91324-92418:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:91324-92418:1:exon

YCL018W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: LEU2
locus tag: YCL018W
EC number: 1.1.1.85
experiment: EXISTENCE:direct assay:GO:0003862 3-isopropylmalate dehydrogenase activity [PMID:3071718]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:4355481]
experiment: EXISTENCE:mutant phenotype:GO:0003862 3-isopropylmalate dehydrogenase activity [PMID:6297759]
experiment: EXISTENCE:mutant phenotype:GO:0006097 glyoxylate cycle [PMID:23642236]
experiment: EXISTENCE:mutant phenotype:GO:0009098 leucine biosynthetic process [PMID:6297759]
note: Beta-isopropylmalate dehydrogenase (IMDH); catalyzes the third step in the leucine biosynthesis pathway; can additionally catalyze the conversion of beta-ethylmalate into alpha-ketovalerate
codon start: 1
product: 3-isopropylmalate dehydrogenase
translation: MSAPKKIVVLPGDHVGQEITAEAIKVLKAISDVRSNVKFDFENHLIGGAAIDATGVPLPDEALEASKKADAVLLGAVGGPKWGTGSVRPEQGLLKIRKELQLYANLRPCNFASDSLLDLSPIKPQFAKGTDFVVVRELVGGIYFGKRKEDDGDGVAWDSEQYTVPEVQRITRMAAFMALQHEPPLPIWSLDKANVLASSRLWRKTVEETIKNEFPTLKVQHQLIDSAAMILVKNPTHLNGIIITSNMFGDIISDEASVIPGSLGLLPSASLASLPDKNTAFGLYEPCHGSAPDLPKNKVNPIATILSAAMMLKLSLNLPEEGKAIEDAVKKVLDAGIRTGDLGGSNSTTEVGDAVAEEVKKILA
SIO_010081: YCL018W
subclass of: SO_0000673
so part of: YCL018W
location: 91324..92418
location: region:91324-92418:1
so has part: feature:91324-92418:1:exon

NP_009911.2
type: Protein
SIO_000068: ncbiprotein

S000000523
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:91324-92418:1:exon

YCL017C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SPL1
gene: NFS1
locus tag: YCL017C
gene synonym: SPL1
so part of: sequence
location: complement(<92777..>94270)
location: region:92777-94270:-1
so has part: feature:92777-94270:-1:exon
subclass of: SO_0000010

850343
type: Gene
SIO_000068: ncbigene

position:92777:-1
position: 92777
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:94270:-1
position: 94270
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:92777-94270:-1:exon

YCL017C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SPL1
gene: NFS1
locus tag: YCL017C
gene synonym: SPL1
product: cysteine desulfurase
transcript id: NM_001178664.1
SIO_010081: YCL017C
subclass of: SO_0000673
so part of: YCL017C
location: complement(<92777..>94270)
location: region:92777-94270:-1
so has part: feature:92777-94270:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:92777-94270:-1:exon

YCL017C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SPL1
gene: NFS1
locus tag: YCL017C
gene synonym: SPL1
EC number: 2.8.1.7
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:19720832]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:10406803|PMID:19720832|PMID:14576278|PMID:16823961|P MID:24769239]
experiment: EXISTENCE:direct assay:GO:0016226 iron-sulfur cluster assembly [PMID:15220327]
experiment: EXISTENCE:direct assay:GO:0031071 cysteine desulfurase activity [PMID:15220327|PMID:12065597]
experiment: EXISTENCE:mutant phenotype:GO:0002098 tRNA wobble uridine modification [PMID:18755837]
experiment: EXISTENCE:mutant phenotype:GO:0005634 nucleus [PMID:11110795]
experiment: EXISTENCE:mutant phenotype:GO:0006879 cellular iron ion homeostasis [PMID:10551871]
experiment: EXISTENCE:mutant phenotype:GO:0016226 iron-sulfur cluster assembly [PMID:12970193]
experiment: EXISTENCE:mutant phenotype:GO:0034227 tRNA thio-modification [PMID:14722066|PMID:15220327]
experiment: EXISTENCE:mutant phenotype:GO:0070903 mitochondrial tRNA thio-modification [PMID:14722066]
experiment: EXISTENCE:physical interaction:GO:1990221 L-cysteine desulfurase complex [PMID:24045011]
note: Cysteine desulfurase involved in iron-sulfur cluster biogenesis; required for thio-modification of mitochondrial and cytoplasmic tRNAs; involved in DNA damage response by providing iron-sulfur cluster cofactors for DNA repair enzymes; essential protein located predominantly in mitochondria
codon start: 1
product: cysteine desulfurase
translation: MLKSTATRSITRLSQVYNVPAATYRACLVSRRFYSPPAAGVKLDDNFSLETHTDIQAAAKAQASARASASGTTPDAVVASGSTAMSHAYQENTGFGTRPIYLDMQATTPTDPRVLDTMLKFYTGLYGNPHSNTHSYGWETNTAVENARAHVAKMINADPKEIIFTSGATESNNMVLKGVPRFYKKTKKHIITTRTEHKCVLEAARAMMKEGFEVTFLNVDDQGLIDLKELEDAIRPDTCLVSVMAVNNEIGVIQPIKEIGAICRKNKIYFHTDAAQAYGKIHIDVNEMNIDLLSISSHKIYGPKGIGAIYVRRRPRVRLEPLLSGGGQERGLRSGTLAPPLVAGFGEAARLMKKEFDNDQAHIKRLSDKLVKGLLSAEHTTLNGSPDHRYPGCVNVSFAYVEGESLLMALRDIALSSGSACTSASLEPSYVLHALGKDDALAHSSIRFGIGRFSTEEEVDYVVKAVSDRVKFLRELSPLWEMVQEGIDLNSIKWSGH
SIO_010081: YCL017C
subclass of: SO_0000673
so part of: YCL017C
location: complement(92777..94270)
location: region:92777-94270:-1
so has part: feature:92777-94270:-1:exon

NP_009912.2
type: Protein
SIO_000068: ncbiprotein

S000000522
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:92777-94270:-1:exon

YCL016C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: DCC1
locus tag: YCL016C
so part of: sequence
location: complement(<94621..>95763)
location: region:94621-95763:-1
so has part: feature:94621-95763:-1:exon
subclass of: SO_0000010

850344
type: Gene
SIO_000068: ncbigene

position:94621:-1
position: 94621
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:95763:-1
position: 95763
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:94621-95763:-1:exon

YCL016C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: DCC1
locus tag: YCL016C
product: Dcc1p
transcript id: NM_001178663.1
SIO_010081: YCL016C
subclass of: SO_0000673
so part of: YCL016C
location: complement(<94621..>95763)
location: region:94621-95763:-1
so has part: feature:94621-95763:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:94621-95763:-1:exon

YCL016C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: DCC1
locus tag: YCL016C
experiment: EXISTENCE:genetic interaction:GO:0007064 mitotic sister chromatid cohesion [PMID:17483413]
experiment: EXISTENCE:mutant phenotype:GO:0007064 mitotic sister chromatid cohesion [PMID:11389843]
experiment: EXISTENCE:mutant phenotype:GO:0034398 telomere tethering at nuclear periphery [PMID:16525505]
experiment: EXISTENCE:mutant phenotype:GO:0035753 maintenance of DNA trinucleotide repeats [PMID:21347277]
experiment: EXISTENCE:physical interaction:GO:0031390 Ctf18 RFC-like complex [PMID:11389843]
note: Subunit of a complex with Ctf8p and Ctf18p; shares some components with Replication Factor C; required for sister chromatid cohesion and telomere length maintenance
codon start: 1
product: Dcc1p
translation: MSINLHSAPEYDPSYKLIQLTPELLDIIQDPVQNHQLRFKSLDKDKSEVVLCSHDKTWVLKQRKHSNTVLLMREFVPEQPITFDETLLFGLSKPYMDVVGFAKTESEFETRETHGELNLNSVPIYNGELDFSDKIMKRSSTKVIGTLEELLENSPCSALEGISKWHKIGGSVKDGVLCILSQDFLFKALHVLLMSAMAESLDLQHLNVEDTHHAVGKDIEDEFNPYTREIIETVLNKFAVQEQEAENNTWRLRIPFIAQWYGIQALRKYVSGISMPIDEFLIKWKSLFPPFFPCDIDIDMLRGYHFKPTDKTVQYIAKSTLPMDPKERFKVLFRLQSQWDLEDIKPLIEELNSRGMKIDSFIMKYARRKRLGKKTVVTSR
SIO_010081: YCL016C
subclass of: SO_0000673
so part of: YCL016C
location: complement(94621..95763)
location: region:94621-95763:-1
so has part: feature:94621-95763:-1:exon

NP_009913.2
type: Protein
SIO_000068: ncbiprotein

S000000521
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:94621-95763:-1:exon

YCL014W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YCL012W
gene: BUD3
locus tag: YCL014W
gene synonym: YCL012W
so part of: sequence
location: <96281..>101191
location: region:96281-101191:1
so has part: feature:96281-101191:1:exon
subclass of: SO_0000010

850345
type: Gene
SIO_000068: ncbigene

position:96281:1
position: 96281
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:101191:1
position: 101191
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:96281-101191:1:exon

YCL014W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YCL012W
gene: BUD3
locus tag: YCL014W
gene synonym: YCL012W
product: Bud3p
transcript id: NM_001178662.1
SIO_010081: YCL014W
subclass of: SO_0000673
so part of: YCL014W
location: <96281..>101191
location: region:96281-101191:1
so has part: feature:96281-101191:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:96281-101191:1:exon

YCL014W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YCL012W
gene: BUD3
locus tag: YCL014W
gene synonym: YCL012W
experiment: EXISTENCE:direct assay:GO:0000142 cellular bud neck contractile ring [PMID:7730410]
experiment: EXISTENCE:direct assay:GO:0005085 guanyl-nucleotide exchange factor activity [PMID:25002677]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:12972503]
experiment: EXISTENCE:direct assay:GO:0043547 positive regulation of GTPase activity [PMID:25002677]
experiment: EXISTENCE:genetic interaction:GO:0043547 positive regulation of GTPase activity [PMID:25002677]
experiment: EXISTENCE:mutant phenotype:GO:0000755 cytogamy [PMID:9744878]
experiment: EXISTENCE:mutant phenotype:GO:0005085 guanyl-nucleotide exchange factor activity [PMID:25002677]
experiment: EXISTENCE:mutant phenotype:GO:0007120 axial cellular bud site selection [PMID:2065354]
note: Guanine nucleotide exchange factor (GEF) for Cdc42p; activates Cdc42p in early G1, accounting for the first stage of biphasic activation, with Cdc24p accounting for the second stage in late G1; involved in the Cdc42p-mediated assembly of the axial landmark that dictates the site for the next round of budding, resulting in the axial budding pattern in haploids; localizes with septins to the bud neck contractile ring in mitosis
codon start: 1
product: Bud3p
translation: MEKDLSSLYSEKKDKENDETLFNIKLSKSVVETTPLNGHSLFDDDKSLSDWTDNVFTQSVFYHGSDDLIWGKFFVCVYKSPNSNKLNAIIFDKLGTSCFESVDISSNSQYYPAIENLSPSDQESNVKKCIAVILLQRYPLLSPSDLSQILSNKSENCDYDPPYAGDLASSCQLITAVPPEDLGKRFFTSGLLQNRFVSSTLLDVIYENNESTIELNNRLVFHLGEQLEQLFNPVTEYSPEQTEYGYKAPEDELPTESDDDLVKAICNELLQLQTNFTFNLVEFLQKFLIALRVRVLNEEINGLSTTKLNRLFPPTIDEVTRINCIFLDSLKTAIPYGSLEVLKACSITIPYFYKAYTRHEAATKNFSKDIKLFIRHFSNVIPEREVYTEMKIESIIKGPQEKLLKLKLIIERLWKSKKWRPKNQEMAKKCYNNIIDVIDSFGKLDSPLHSYSTRVFTPSGKILTELAKCWPVELQYKWLKRRVVGVYDVVDLNDENKRNLLVIFSDYVVFINILEAESYYTSDGSNRPLISDILMNSLINEVPLPSKIPKLKVERHCYIDEVLVSILDKSTLRFDRLKGKDSFSMVCKLSSAFISSSSVADLITKARILEKDTAFHLFKASRSHFTLYSTAHELCAYDSEKIKSKFALFLNIPPSKEILEVNNLHLAFFARFCSNDGRDNIVILDVLTKHDDKHIEVTSDNIVFTIINQLAIEIPICFSSLNSSMAKDLLCVNENLIKNLEHQLEEVKHPSTDEHRAVNSKLSGASDFDATHEKKRSYGTITTFRSYTSDLKDSPSGDNSNVTKETKEILPVKPTKKSSKKPREIQKKTKTNASKAEHIEKKKPNKGKGFFGVLKNVFGSKSKSKPSPVQRVPKKISQRHPKSPVKKPMTSEKKSSPKRAVVSSPKIKKKSTSFSTKESQTAKSSLRAVEFKSDDLIGKPPDVGNGAHPQENTRISSVVRDTKYVSYNPSQPVTENTSNEKNVEPKADQSTKQDNISNFADVEVSASSYPEKLDAETDDQIIGKATNSSSVHGNKELPDLAEVTTANRVSTTSAGDQRIDTQSEFLRAADVENLSDDDEHRQNESRVFNDDLFGDFIPKHYRNKQENINSSSNLFPEGKVPQEKGVSNENTNISLKTNEDASTLTQKLSPQASKVLTENSNELKDTNNEGKDAKDIKLGDDYSDKETAKEITKPKNFVEGITERKEIFPTIPRLAPPASKINFQRSPSYIELFQGMRVVLDKHDAHYNWKRLASQVSLSEGLKVNTEEDAAIINKSQDDAKAERMTQISEVIEYEMQQPIPTYLPKAHLDDSGIEKSDDKFFEIEEELKEELKGSKTGNEDVGNNNPSNSIPKIEKPPAFKVIRTSPVRIIGRTFEDTRKYENGSPSDISFTYDTHNNDEPDKRLMELKFPSQDEIPDDRFYTPAEEPTAEFPVEELPNTPRSINVTTSNNKSTDDKLSSGNIDQKPTELLDDLEFSSFNIAFGNTSMSTDNMKISSDLSSNKTVLGNAQKVQESPSGPLIYVLPQSSTKHEKEGFLRKKQKDEPIWVSPSKIDFADLSRRTKALTPERNTVPLKNNDSRKYKYTGEGSIGNMTNMLLTKDASYAYLKDFVALSDDEDEDGKQNCAVGGPEKLKFY
SIO_010081: YCL014W
subclass of: SO_0000673
so part of: YCL014W
location: 96281..101191
location: region:96281-101191:1
so has part: feature:96281-101191:1:exon

NP_009914.2
type: Protein
SIO_000068: ncbiprotein

S000000520
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:96281-101191:1:exon

YCL012C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YCL011C-A
locus tag: YCL012C
gene synonym: YCL011C-A
so part of: sequence
location: complement(<101317..>101788)
location: region:101317-101788:-1
so has part: feature:101317-101788:-1:exon
subclass of: SO_0000010

2746859
type: Gene
SIO_000068: ncbigene

position:101317:-1
position: 101317
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:101788:-1
position: 101788
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:101317-101788:-1:exon

YCL012C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YCL011C-A
locus tag: YCL012C
gene synonym: YCL011C-A
product: uncharacterized protein
transcript id: NM_001184672.1
SIO_010081: YCL012C
subclass of: SO_0000673
so part of: YCL012C
location: complement(join(<101317..101633,101701..>101788))
location: region:101317-101788:-1
so has part: feature:101701-101788:-1:exon
so has part: feature:101317-101633:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:101701-101788:-1:exon

position:101701:-1
position: 101701
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:101317-101633:-1:exon

position:101633:-1
position: 101633
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YCL012C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YCL011C-A
locus tag: YCL012C
gene synonym: YCL011C-A
note: hypothetical protein; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum and vacuole respectively; orthologs are present in S. bayanus, S. paradoxus and Ashbya gossypii; YCL012C is not an essential gene
codon start: 1
product: uncharacterized protein
translation: MKSLFYLKLLLWVVLLSLCLLMAHRKTKVADKFRALRSRIQLRFNRHIRLNDSFADDLENGLHSRNFDIISENSNDVRGGLDDVSKNEIKQIMENDNVDFDKARLLYMERKFGQNGIAPDGTPIDPKAFTFDSR
SIO_010081: YCL012C
subclass of: SO_0000673
so part of: YCL012C
location: complement(join(101317..101633,101701..101788))
location: region:101317-101788:-1
so has part: feature:101701-101788:-1:exon
so has part: feature:101317-101633:-1:exon

NP_976246.1
type: Protein
SIO_000068: ncbiprotein

S000029705
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:101701-101788:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:101317-101633:-1:exon

YCL011C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RLF6
gene: GBP2
locus tag: YCL011C
gene synonym: RLF6
so part of: sequence
location: complement(<102075..>103358)
location: region:102075-103358:-1
so has part: feature:102075-103358:-1:exon
subclass of: SO_0000010

850346
type: Gene
SIO_000068: ncbigene

position:102075:-1
position: 102075
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:103358:-1
position: 103358
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:102075-103358:-1:exon

YCL011C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RLF6
gene: GBP2
locus tag: YCL011C
gene synonym: RLF6
product: single-stranded telomeric DNA-binding/mRNA-binding protein
transcript id: NM_001178660.1
SIO_010081: YCL011C
subclass of: SO_0000673
so part of: YCL011C
location: complement(<102075..>103358)
location: region:102075-103358:-1
so has part: feature:102075-103358:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:102075-103358:-1:exon

YCL011C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RLF6
gene: GBP2
locus tag: YCL011C
gene synonym: RLF6
experiment: EXISTENCE:direct assay:GO:0000723 telomere maintenance [PMID:12519786]
experiment: EXISTENCE:direct assay:GO:0003682 chromatin binding [PMID:14769921]
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:12634846|PMID:14769921|PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:12634846|PMID:22932476|PMID:26359986]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0005844 polysome [PMID:33910495]
experiment: EXISTENCE:direct assay:GO:0010494 cytoplasmic stress granule [PMID:18981231|PMID:26777405|PMID:33910495]
experiment: EXISTENCE:direct assay:GO:0043047 single-stranded telomeric DNA binding [PMID:7777547|PMID:7800479]
experiment: EXISTENCE:genetic interaction:GO:0000723 telomere maintenance [PMID:12519786]
experiment: EXISTENCE:mutant phenotype:GO:0000723 telomere maintenance [PMID:12519786]
experiment: EXISTENCE:mutant phenotype:GO:0016973 poly(A)+ mRNA export from nucleus [PMID:12634846]
experiment: EXISTENCE:mutant phenotype:GO:0043047 single-stranded telomeric DNA binding [PMID:7777547]
experiment: EXISTENCE:mutant phenotype:GO:0071028 nuclear mRNA surveillance [PMID:24452287]
note: Poly(A+) RNA-binding protein; key surveillance factor for the selective export of spliced mRNAs from the nucleus to the cytoplasm; preference for intron-containing genes; similar to Npl3p; also binds single-stranded telomeric repeat sequence in vitro; relocalizes to the cytosol in response to hypoxia; GBP2 has a paralog, HRB1, that arose from the whole genome duplication
codon start: 1
product: single-stranded telomeric DNA-binding/mRNA-binding protein
translation: MERELGMYGNDRSRSRSPVRRRLSDDRDRYDDYNDSSSNNGNGSRRQRRDRGSRFNDRYDQSYGGSRYHDDRNWPPRRGGRGRGGSRSFRGGRGGGRGRTLGPIVERDLERQFDATKRNFENSIFVRNLTFDCTPEDLKELFGTVGEVVEADIITSKGHHRGMGTVEFTKNESVQDAISKFDGALFMDRKLMVRQDNPPPEAAKEFSKKATREEIDNGFEVFIINLPYSMNWQSLKDMFKECGHVLRADVELDFNGFSRGFGSVIYPTEDEMIRAIDTFNGMEVEGRVLEVREGRFNKRKNNDRYNQRREDLEDTRGTEPGLAQDAAVHIDETAAKFTEGVNPGGDRNCFIYCSNLPFSTARSDLFDLFGPIGKINNAELKPQENGQPTGVAVVEYENLVDADFCIQKLNNYNYGGCSLQISYARRD
SIO_010081: YCL011C
subclass of: SO_0000673
so part of: YCL011C
location: complement(102075..103358)
location: region:102075-103358:-1
so has part: feature:102075-103358:-1:exon

NP_009916.1
type: Protein
SIO_000068: ncbiprotein

S000000517
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:102075-103358:-1:exon

YCL010C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SGF29
locus tag: YCL010C
so part of: sequence
location: complement(<103571..>104350)
location: region:103571-104350:-1
so has part: feature:103571-104350:-1:exon
subclass of: SO_0000010

850347
type: Gene
SIO_000068: ncbigene

position:103571:-1
position: 103571
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:104350:-1
position: 104350
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:103571-104350:-1:exon

YCL010C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SGF29
locus tag: YCL010C
product: Sgf29p
transcript id: NM_001178659.1
SIO_010081: YCL010C
subclass of: SO_0000673
so part of: YCL010C
location: complement(<103571..>104350)
location: region:103571-104350:-1
so has part: feature:103571-104350:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:103571-104350:-1:exon

YCL010C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SGF29
locus tag: YCL010C
experiment: EXISTENCE:direct assay:GO:0000124 SAGA complex [PMID:12052880]
experiment: EXISTENCE:direct assay:GO:0035064 methylated histone binding [PMID:21685874]
experiment: EXISTENCE:mutant phenotype:GO:0008104 protein localization [PMID:22224423]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:21685874]
experiment: EXISTENCE:mutant phenotype:GO:0072742 SAGA complex localization to transcription regulatory region [PMID:21685874]
experiment: EXISTENCE:mutant phenotype:GO:0140671 ADA complex [PMID:21734642]
experiment: EXISTENCE:physical interaction:GO:0140671 ADA complex [PMID:21734642]
note: Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes; HAT/Core module also contains Gcn5p, Ngg1p, and Ada2p; binds methylated histone H3K4; involved in transcriptional regulation through SAGA and TBP recruitment to target promoters and H3 acetylation
codon start: 1
product: Sgf29p
translation: MDGYWDVVVSSLQDIYNANEVIPFDDELQTKKLNFLNMSKDQLQLHLNTFQEHMENVNRVHRILDNVRSNLSLMLNQSREEKSEENTEDAEEGEGTRMALSQGKKAVGKVGRSYWTSEYNPNAPILVGSEVAYKPRRGSADGEWIQCEVLKVVADGTRFEVRDPEPDELGNSGKVYKCNRKELLLIPPGFPTKNYPPGTKVLARYPETTTFYPAIVIGTKRDGTCRLRFDGEEEVDKETEVTRRLVLPSPTALANLARK
SIO_010081: YCL010C
subclass of: SO_0000673
so part of: YCL010C
location: complement(103571..104350)
location: region:103571-104350:-1
so has part: feature:103571-104350:-1:exon

NP_009917.1
type: Protein
SIO_000068: ncbiprotein

S000000516
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:103571-104350:-1:exon

YCL009C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ILV6
locus tag: YCL009C
so part of: sequence
location: complement(<104619..>105548)
location: region:104619-105548:-1
so has part: feature:104619-105548:-1:exon
subclass of: SO_0000010

850348
type: Gene
SIO_000068: ncbigene

position:104619:-1
position: 104619
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:105548:-1
position: 105548
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:104619-105548:-1:exon

YCL009C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ILV6
locus tag: YCL009C
product: acetolactate synthase regulatory subunit
transcript id: NM_001178658.1
SIO_010081: YCL009C
subclass of: SO_0000673
so part of: YCL009C
location: complement(<104619..>105548)
location: region:104619-105548:-1
so has part: feature:104619-105548:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:104619-105548:-1:exon

YCL009C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ILV6
locus tag: YCL009C
experiment: EXISTENCE:direct assay:GO:0003984 acetolactate synthase activity [PMID:16390333|PMID:8972574]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005948 acetolactate synthase complex [PMID:10213630]
experiment: EXISTENCE:direct assay:GO:0009082 branched-chain amino acid biosynthetic process [PMID:8972574]
experiment: EXISTENCE:direct assay:GO:0030234 enzyme regulator activity [PMID:8972574]
experiment: EXISTENCE:direct assay:GO:0042645 mitochondrial nucleoid [PMID:15692048]
experiment: EXISTENCE:mutant phenotype:GO:0003984 acetolactate synthase activity [PMID:16390333]
note: Regulatory subunit of acetolactate synthase; acetolactate synthase catalyzes the first step of branched-chain amino acid biosynthesis; enhances activity of the Ilv2p catalytic subunit, localizes to mitochondria
codon start: 1
product: acetolactate synthase regulatory subunit
translation: MLRSLLQSGHRRVVASSCATMVRCSSSSTSALAYKQMHRHATRPPLPTLDTPSWNANSAVSSIIYETPAPSRQPRKQHVLNCLVQNEPGVLSRVSGTLAARGFNIDSLVVCNTEVKDLSRMTIVLQGQDGVVEQARRQIEDLVPVYAVLDYTNSEIIKRELVMARISLLGTEYFEDLLLHHHTSTNAGAADSQELVAEIREKQFHPANLPASEVLRLKHEHLNDITNLTNNFGGRVVDISETSCIVELSAKPTRISAFLKLVEPFGVLECARSGMMALPRTPLKTSTEEAADEDEKISEIVDISQLPPG
SIO_010081: YCL009C
subclass of: SO_0000673
so part of: YCL009C
location: complement(104619..105548)
location: region:104619-105548:-1
so has part: feature:104619-105548:-1:exon

NP_009918.1
type: Protein
SIO_000068: ncbiprotein

S000000515
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:104619-105548:-1:exon

YCL008C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: AGS1
alternative label: VPL15
alternative label: VPS23
gene: STP22
locus tag: YCL008C
gene synonym: AGS1; VPL15; VPS23
so part of: sequence
location: complement(<105696..>106853)
location: region:105696-106853:-1
so has part: feature:105696-106853:-1:exon
subclass of: SO_0000010

850349
type: Gene
SIO_000068: ncbigene

position:105696:-1
position: 105696
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:106853:-1
position: 106853
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:105696-106853:-1:exon

YCL008C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: AGS1
alternative label: VPL15
alternative label: VPS23
gene: STP22
locus tag: YCL008C
gene synonym: AGS1; VPL15; VPS23
product: ubiquitin-binding ESCRT-I subunit protein STP22
transcript id: NM_001178657.1
SIO_010081: YCL008C
subclass of: SO_0000673
so part of: YCL008C
location: complement(<105696..>106853)
location: region:105696-106853:-1
so has part: feature:105696-106853:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:105696-106853:-1:exon

YCL008C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: AGS1
alternative label: VPL15
alternative label: VPS23
gene: STP22
locus tag: YCL008C
gene synonym: AGS1; VPL15; VPS23
experiment: EXISTENCE:curator inference:GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [PMID:15086794]
experiment: EXISTENCE:direct assay:GO:0000813 ESCRT I complex [PMID:15044434]
experiment: EXISTENCE:direct assay:GO:0005768 endosome [PMID:11511343]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0009898 cytoplasmic side of plasma membrane [PMID:20028738]
experiment: EXISTENCE:direct assay:GO:0043130 ubiquitin binding [PMID:19380877]
experiment: EXISTENCE:direct assay:GO:0061709 reticulophagy [PMID:31802527]
experiment: EXISTENCE:mutant phenotype:GO:0006612 protein targeting to membrane [PMID:11511343]
experiment: EXISTENCE:mutant phenotype:GO:0006623 protein targeting to vacuole [PMID:11511343]
experiment: EXISTENCE:mutant phenotype:GO:0045324 late endosome to vacuole transport [PMID:17145965]
experiment: EXISTENCE:mutant phenotype:GO:1902915 negative regulation of protein polyubiquitination [PMID:23645667]
experiment: EXISTENCE:mutant phenotype:GO:1904669 ATP export [PMID:26585826]
experiment: EXISTENCE:physical interaction:GO:0000813 ESCRT I complex [PMID:16615894]
note: Component of the ESCRT-I complex; ESCRT-I is involved in ubiquitin-dependent sorting of proteins into the endosome; prevents polyubiquitination of the arrestin-related protein Rim8p, thereby directing its monoubiquitination by Rsp5p; homologous to the mouse and human Tsg101 tumor susceptibility gene; mutants exhibit a Class E Vps phenotype
codon start: 1
product: ubiquitin-binding ESCRT-I subunit protein STP22
translation: MSANGKISVPEAVVNWLFKVIQPIYNDGRTTFHDSLALLDNFHSLRPRTRVFTHSDGTPQLLLSIYGTISTGEDGSSPHSIPVIMWVPSMYPVKPPFISINLENFDMNTISSSLPIQEYIDSNGWIALPILHCWDPAAMNLIMVVQELMSLLHEPPQDQAPSLPPKPNTQLQQEQNTPPLPPKPKSPHLKPPLPPPPPPQPASNALDLMDMDNTDISPTNHHEMLQNLQTVVNELYREDVDYVADKILTRQTVMQESIARFHEIIAIDKNHLRAVEQAIEQTMHSLNAQIDVLTANRAKVQQFSSTSHVDDEDVNSIAVAKTDGLNQLYNLVAQDYALTDTIECLSRMLHRGTIPLDTFVKQGRELARQQFLVRWHIQRITSPLS
SIO_010081: YCL008C
subclass of: SO_0000673
so part of: YCL008C
location: complement(105696..106853)
location: region:105696-106853:-1
so has part: feature:105696-106853:-1:exon

NP_009919.3
type: Protein
SIO_000068: ncbiprotein

S000000514
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:105696-106853:-1:exon

YCL005W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CWH36
alternative label: LDB10
gene: VMA9
locus tag: YCL005W-A
gene synonym: CWH36; LDB10
so part of: sequence
location: <107023..>107417
location: region:107023-107417:1
so has part: feature:107023-107417:1:exon
subclass of: SO_0000010

2732686
type: Gene
SIO_000068: ncbigene

position:107023:1
position: 107023
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:107417:1
position: 107417
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:107023-107417:1:exon

YCL005W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CWH36
alternative label: LDB10
gene: VMA9
locus tag: YCL005W-A
gene synonym: CWH36; LDB10
product: H(+)-transporting V0 sector ATPase subunit e
transcript id: NM_001184518.1
SIO_010081: YCL005W-A
subclass of: SO_0000673
so part of: YCL005W-A
location: join(<107023..107033,107111..107191,107288..>107417)
location: region:107023-107417:1
so has part: feature:107023-107033:1:exon
so has part: feature:107111-107191:1:exon
so has part: feature:107288-107417:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:107023-107033:1:exon

position:107033:1
position: 107033
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:107111-107191:1:exon

position:107111:1
position: 107111
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:107191:1
position: 107191
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 3
SIO_000628: feature:107288-107417:1:exon

position:107288:1
position: 107288
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YCL005W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CWH36
alternative label: LDB10
gene: VMA9
locus tag: YCL005W-A
gene synonym: CWH36; LDB10
experiment: EXISTENCE:mutant phenotype:GO:0000032 cell wall mannoprotein biosynthetic process [PMID:14734024]
experiment: EXISTENCE:mutant phenotype:GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain [PMID:14970230]
experiment: EXISTENCE:mutant phenotype:GO:0000329 fungal-type vacuole membrane [PMID:14970230]
experiment: EXISTENCE:mutant phenotype:GO:0007035 vacuolar acidification [PMID:14970230]
experiment: EXISTENCE:mutant phenotype:GO:0042625 ATPase-coupled ion transmembrane transporter activity [PMID:14970230]
experiment: EXISTENCE:mutant phenotype:GO:0055085 transmembrane transport [PMID:14970230]
experiment: EXISTENCE:mutant phenotype:GO:0065003 protein-containing complex assembly [PMID:16569636]
experiment: EXISTENCE:physical interaction:GO:0065003 protein-containing complex assembly [PMID:16569636]
note: Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex; essential for vacuolar acidification; interacts with the V-ATPase assembly factor Vma21p in the ER; involved in V0 biogenesis
codon start: 1
product: H(+)-transporting V0 sector ATPase subunit e
translation: MSSFYTVVGVFIVVSAMSVLFWIMAPKNNQAVWRSTVILTLAMMFLMWAITFLCQLHPLVAPRRSDLRPEFAE
SIO_010081: YCL005W-A
subclass of: SO_0000673
so part of: YCL005W-A
location: join(107023..107033,107111..107191,107288..107417)
location: region:107023-107417:1
so has part: feature:107023-107033:1:exon
so has part: feature:107111-107191:1:exon
so has part: feature:107288-107417:1:exon

NP_958835.1
type: Protein
SIO_000068: ncbiprotein

S000028508
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:107023-107033:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:107111-107191:1:exon

urn:…
SIO_000300: 3
SIO_000628: feature:107288-107417:1:exon

YNCC0003C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SNR43
locus tag: YNCC0003C
so part of: sequence
location: complement(107504..107712)
location: region:107504-107712:-1
so has part: feature:107504-107712:-1:exon
subclass of: SO_0000578

9164875
type: Gene
SIO_000068: ncbigene

position:107504:-1
position: 107504
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:107712:-1
position: 107712
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:107504-107712:-1:exon

YNCC0003C
type: Non Coding RNA
subclass of: SO_0000655
RO_0002162: 559292
nc RNA class: snoRNA
gene: SNR43
locus tag: YNCC0003C
product: SNR43
experiment: EXISTENCE:curator inference:GO:0005730 nucleolus [PMID:15923376]
experiment: EXISTENCE:mutant phenotype:GO:0030559 rRNA pseudouridylation guide activity [PMID:18332121|PMID:15923376]
experiment: EXISTENCE:mutant phenotype:GO:0031118 rRNA pseudouridine synthesis [PMID:15923376|PMID:18332121]
experiment: EXISTENCE:physical interaction:GO:0031429 box H/ACA snoRNP complex [PMID:15923376]
note: H/ACA box small nucleolar RNA (snoRNA); guides pseudouridylation of large subunit (LSU) rRNA at position U966 and of 5.8S rRNA at position 73
transcript id: NR_132155.1
SIO_010081: YNCC0003C
subclass of: SO_0000673
so part of: YNCC0003C
location: complement(107504..107712)
location: region:107504-107712:-1
so has part: feature:107504-107712:-1:exon

S000006503
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:107504-107712:-1:exon

YCL005W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: LDB16
locus tag: YCL005W
so part of: sequence
location: <108021..>108791
location: region:108021-108791:1
so has part: feature:108021-108791:1:exon
subclass of: SO_0000010

850351
type: Gene
SIO_000068: ncbigene

position:108021:1
position: 108021
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:108791:1
position: 108791
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:108021-108791:1:exon

YCL005W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: LDB16
locus tag: YCL005W
product: Ldb16p
transcript id: NM_001178654.1
SIO_010081: YCL005W
subclass of: SO_0000673
so part of: YCL005W
location: <108021..>108791
location: region:108021-108791:1
so has part: feature:108021-108791:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:108021-108791:1:exon

YCL005W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: LDB16
locus tag: YCL005W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:24434579]
experiment: EXISTENCE:direct assay:GO:0005811 lipid droplet [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0034389 lipid droplet organization [PMID:26572621]
experiment: EXISTENCE:mutant phenotype:GO:0090155 negative regulation of sphingolipid biosynthetic process [PMID:31594806]
note: Protein involved in lipid droplet (LD) assembly; forms a complex with Sei1p at ER-LD contact sites, stabilizing contact sites; ensures that LDs bud from the ER towards the cytosolic side of the membrane; null mutants have decreased net negative cell surface charge and localized accumulation of phosphatidic acid (PA) marker proteins; GFP-fusion protein expression is induced in response to MMS; null mutant can be complemented by the human seipin, BSCL2
codon start: 1
product: Ldb16p
translation: MFVVDWSVQLCMGVISPLFRALVQLPLSIFVWNGFQLVALPINIPLRLFLGTSLSRLVAQTSTLDFYVVLTLFQYFAVLCAFGSIIGLIFGFILGVFHSICGVPSVYISLEWKRWFAPIRTVLERASTSIVNIMRGQTIAPIPMPKPNPTHISKPNMKKFHDEPGADDMTITHDVNCYITPCQTPTNEKIQHYNNDSFNTTTTDDEPTDIWDRSDTYQNSFVTNETLMSLSNRAKLRRNASDADIVNIKILRRNSR
SIO_010081: YCL005W
subclass of: SO_0000673
so part of: YCL005W
location: 108021..108791
location: region:108021-108791:1
so has part: feature:108021-108791:1:exon

NP_009922.2
type: Protein
SIO_000068: ncbiprotein

S000000511
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:108021-108791:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS307; Autonomously Replicating Sequence on Chromosome III
so part of: sequence
location: 108727..109060
location: region:108727-109060:1
so has part: feature:108727-109060:1:region

S000028484
type: SGD
SIO_000068: sgd

position:108727:1
position: 108727
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:109060:1
position: 109060
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:108727-109060:1:region

YCL004W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PEL1
alternative label: YCL003W
gene: PGS1
locus tag: YCL004W
gene synonym: PEL1; YCL003W
so part of: sequence
location: <109105..>110670
location: region:109105-110670:1
so has part: feature:109105-110670:1:exon
subclass of: SO_0000010

850352
type: Gene
SIO_000068: ncbigene

position:109105:1
position: 109105
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:110670:1
position: 110670
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:109105-110670:1:exon

YCL004W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PEL1
alternative label: YCL003W
gene: PGS1
locus tag: YCL004W
gene synonym: PEL1; YCL003W
product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
transcript id: NM_001178653.1
SIO_010081: YCL004W
subclass of: SO_0000673
so part of: YCL004W
location: <109105..>110670
location: region:109105-110670:1
so has part: feature:109105-110670:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:109105-110670:1:exon

YCL004W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PEL1
alternative label: YCL003W
gene: PGS1
locus tag: YCL004W
gene synonym: PEL1; YCL003W
EC number: 2.7.8.5
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:9799363]
experiment: EXISTENCE:mutant phenotype:GO:0008444 CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity [PMID:9545322]
experiment: EXISTENCE:mutant phenotype:GO:0032049 cardiolipin biosynthetic process [PMID:9545322]
note: Phosphatidylglycerolphosphate synthase; catalyzes the synthesis of phosphatidylglycerolphosphate from CDP-diacylglycerol and sn-glycerol 3-phosphate in the first committed and rate-limiting step of cardiolipin biosynthesis
codon start: 1
product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
translation: MTTRLLQLTRPHYRLLSLPLQKPFNIKRQMSAANPSPFGNYLNTITKSLQQNLQTCFHFQAKEIDIIESPSQFYDLLKTKILNSQNRIFIASLYLGKSETELVDCISQALTKNPKLKVSFLLDGLRGTRELPSACSATLLSSLVAKYGSERVDCRLYKTPAYHGWKKVLVPKRFNEGLGLQHMKIYGFDNEVILSGANLSNDYFTNRQDRYYLFKSRNFSNYYFKLHQLISSFSYQIIKPMVDGSINIIWPDSNPTVEPTKNKRLFLREASQLLDGFLKSSKQSLPITAVGQFSTLVYPISQFTPLFPKYNDKSTEKRTILSLLSTITSNAISWTFTAGYFNILPDIKAKLLATPVAEANVITASPFANGFYQSKGVSSNLPGAYLYLSKKFLQDVCRYRQDHAITLREWQRGVVNKPNGWSYHAKGIWLSARDKNDANNWKPFITVIGSSNYTRRAYSLDLESNALIITRDEELRKKMKAELDNLLQYTKPVTLEDFQSDPERHVGTGVKIATSILGKKL
SIO_010081: YCL004W
subclass of: SO_0000673
so part of: YCL004W
location: 109105..110670
location: region:109105-110670:1
so has part: feature:109105-110670:1:exon

NP_009923.2
type: Protein
SIO_000068: ncbiprotein

S000000510
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:109105-110670:1:exon

YCL002C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCL002C
so part of: sequence
location: complement(<110808..>111675)
location: region:110808-111675:-1
so has part: feature:110808-111675:-1:exon
subclass of: SO_0000010

850353
type: Gene
SIO_000068: ncbigene

position:110808:-1
position: 110808
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:111675:-1
position: 111675
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:110808-111675:-1:exon

YCL002C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCL002C
product: uncharacterized protein
transcript id: NM_001178652.2
SIO_010081: YCL002C
subclass of: SO_0000673
so part of: YCL002C
location: complement(join(<110808..111557,111634..>111675))
location: region:110808-111675:-1
so has part: feature:111634-111675:-1:exon
so has part: feature:110808-111557:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:111634-111675:-1:exon

position:111634:-1
position: 111634
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:110808-111557:-1:exon

position:111557:-1
position: 111557
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YCL002C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YCL002C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
note: hypothetical protein; YCL002C is not an essential gene
codon start: 1
product: uncharacterized protein
translation: MLVIVLQGLAGFLSIIAILCQKRYNKLHRSIYGLSYDLFLLDFVGNGLYLYCALHYCYSSLVREQLSQRFPLFYPLNDARSIPISSFLILKDFCVSCCCMMVLRQLYYYRSTKHIYQGISITSIIIISVFLVLGIFTYGCSISNLPLKNSGKFGVFYLEHINYLWVMANLLKCFKYVPQMSINWMGCSTVGLSSKFALISFLAESIDLLGRLVIPTNALFYEIPFNSTPFWVKLIQFVTLLVILCQVQYVYVGRKPRLPKGKL
SIO_010081: YCL002C
subclass of: SO_0000673
so part of: YCL002C
location: complement(join(110808..111557,111634..111675))
location: region:110808-111675:-1
so has part: feature:111634-111675:-1:exon
so has part: feature:110808-111557:-1:exon

NP_009924.4
type: Protein
SIO_000068: ncbiprotein

S000000508
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:111634-111675:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:110808-111557:-1:exon

YCL001W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RER1
locus tag: YCL001W
so part of: sequence
location: <111916..>112482
location: region:111916-112482:1
so has part: feature:111916-112482:1:exon
subclass of: SO_0000010

850354
type: Gene
SIO_000068: ncbigene

position:111916:1
position: 111916
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:112482:1
position: 112482
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:111916-112482:1:exon

YCL001W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RER1
locus tag: YCL001W
product: protein retrieval receptor
transcript id: NM_001178651.1
SIO_010081: YCL001W
subclass of: SO_0000673
so part of: YCL001W
location: <111916..>112482
location: region:111916-112482:1
so has part: feature:111916-112482:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:111916-112482:1:exon

YCL001W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RER1
locus tag: YCL001W
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:22761830]
experiment: EXISTENCE:direct assay:GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [PMID:11238450]
experiment: EXISTENCE:direct assay:GO:0030134 COPII-coated ER to Golgi transport vesicle [PMID:11157978]
experiment: EXISTENCE:direct assay:GO:0030137 COPI-coated vesicle [PMID:11238450]
experiment: EXISTENCE:mutant phenotype:GO:0006621 protein retention in ER lumen [PMID:8707815]
experiment: EXISTENCE:mutant phenotype:GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [PMID:11238450]
experiment: EXISTENCE:mutant phenotype:GO:0030137 COPI-coated vesicle [PMID:11238450]
note: Protein involved in retention of membrane proteins; including Sec12p, in the ER; localized to Golgi; functions as a retrieval receptor in returning membrane proteins to the ER
codon start: 1
product: protein retrieval receptor
translation: MDYDSSDTMNGGSSNPLITKMNTMKLLYQHYLDKVTPHAKERWAVLGGLLCLFMVRITMAEGWYVICYGLGLFLLNQFLAFLTPKFDMSLQQDEENNELEAGEKSEEFRPFIRRLPEFKFWYNSIRATVISLLLSLFSIFDIPVFWPILLMYFILLFFLTMRRQIQHMIKYRYIPLDIGKKKYSHSSN
SIO_010081: YCL001W
subclass of: SO_0000673
so part of: YCL001W
location: 111916..112482
location: region:111916-112482:1
so has part: feature:111916-112482:1:exon

NP_009925.1
type: Protein
SIO_000068: ncbiprotein

S000000507
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:111916-112482:1:exon

YCL001W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCL001W-A
so part of: sequence
location: <113080..>113541
location: region:113080-113541:1
so has part: feature:113080-113541:1:exon
subclass of: SO_0000010

850355
type: Gene
SIO_000068: ncbigene

position:113080:1
position: 113080
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:113541:1
position: 113541
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:113080-113541:1:exon

YCL001W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCL001W-A
product: uncharacterized protein
transcript id: NM_001184314.1
SIO_010081: YCL001W-A
subclass of: SO_0000673
so part of: YCL001W-A
location: <113080..>113541
location: region:113080-113541:1
so has part: feature:113080-113541:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:113080-113541:1:exon

YCL001W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YCL001W-A
note: hypothetical protein; YCL001W-A gene has similarity to DOM34 and is present in a region duplicated between chromosomes XIV and III
codon start: 1
product: uncharacterized protein
translation: MTFLQFINNNRQEGQGYISEKLFKTKKNEMIRKTVTNLVAVRLKNLSHEFDVIENYLRYIASTSEHLFTAIKRHFNKCARKLLKEAIDSKSNSETATVVLQEGFSGICLLKASSIILKLKLKFPKKKDRTDISKLCDKKERMTQWLEISILMN
SIO_010081: YCL001W-A
subclass of: SO_0000673
so part of: YCL001W-A
location: 113080..113541
location: region:113080-113541:1
so has part: feature:113080-113541:1:exon

NP_009926.1
type: Protein
SIO_000068: ncbiprotein

S000007221
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:113080-113541:1:exon

YCL001W-B
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCL001W-B
so part of: sequence
location: <113770..>114024
location: region:113770-114024:1
so has part: feature:113770-114024:1:exon
subclass of: SO_0000010

850356
type: Gene
SIO_000068: ncbigene

position:113770:1
position: 113770
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:114024:1
position: 114024
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:113770-114024:1:exon

YCL001W-B
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCL001W-B
product: uncharacterized protein
transcript id: NM_001184462.1
SIO_010081: YCL001W-B
subclass of: SO_0000673
so part of: YCL001W-B
location: <113770..>114024
location: region:113770-114024:1
so has part: feature:113770-114024:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:113770-114024:1:exon

YCL001W-B
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YCL001W-B
note: hypothetical protein; present in a region duplicated between chromosomes XIV and III; YCL001W-B has a paralog, DOM34, that arose from the whole genome duplication
codon start: 1
product: uncharacterized protein
translation: MDDFLEHLSKDDNKAWYGAEETERAAKLDAIETLLITDSVLKRNDVKKREKYLDLIENSGNNNGKIFVLSTSKITVSNLTNQQI
SIO_010081: YCL001W-B
subclass of: SO_0000673
so part of: YCL001W-B
location: 113770..114024
location: region:113770-114024:1
so has part: feature:113770-114024:1:exon

NP_076878.1
type: Protein
SIO_000068: ncbiprotein

S000007596
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:113770-114024:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS308; Autonomously Replicating Sequence on Chromosome III
so part of: sequence
location: 114321..114939
location: region:114321-114939:1
so has part: feature:114321-114939:1:region

S000028485
type: SGD
SIO_000068: sgd

position:114321:1
position: 114321
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:114939:1
position: 114939
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:114321-114939:1:region

centromere
type: Centromere
subclass of: SO_0000577
RO_0002162: 559292
note: CEN3; Chromosome III centromere
so part of: sequence
location: 114385..114501
location: region:114385-114501:1
so has part: feature:114385-114501:1:region

S000006465
type: SGD
SIO_000068: sgd

position:114385:1
position: 114385
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:114501:1
position: 114501
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:114385-114501:1:region

centromere
type: Centromere
subclass of: SO_0000577
RO_0002162: 559292
note: CEN3_CDEI of CEN3
so part of: sequence
location: 114385..114394
location: region:114385-114394:1
so has part: feature:114385-114394:1:region

position:114394:1
position: 114394
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:114385-114394:1:region

centromere
type: Centromere
subclass of: SO_0000577
RO_0002162: 559292
note: CEN3_CDEII of CEN3
so part of: sequence
location: 114395..114476
location: region:114395-114476:1
so has part: feature:114395-114476:1:region

position:114395:1
position: 114395
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:114476:1
position: 114476
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:114395-114476:1:region

centromere
type: Centromere
subclass of: SO_0000577
RO_0002162: 559292
note: CEN3_CDEIII of CEN3
so part of: sequence
location: 114477..114501
location: region:114477-114501:1
so has part: feature:114477-114501:1:region

position:114477:1
position: 114477
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:114477-114501:1:region

YCR001W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCR001W
so part of: sequence
location: <115685..>115999
location: region:115685-115999:1
so has part: feature:115685-115999:1:exon
subclass of: SO_0000010

850357
type: Gene
SIO_000068: ncbigene

position:115685:1
position: 115685
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:115999:1
position: 115999
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:115685-115999:1:exon

YCR001W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCR001W
product: uncharacterized protein
transcript id: NM_001348893.1
SIO_010081: YCR001W
subclass of: SO_0000673
so part of: YCR001W
location: <115685..>115999
location: region:115685-115999:1
so has part: feature:115685-115999:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:115685-115999:1:exon

YCR001W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YCR001W
note: hypothetical protein; conserved among S. cerevisiae strains; YCR001W is not an essential gene
codon start: 1
product: uncharacterized protein
translation: MLYLLKKLKHIDSYGESNLSMFYLKFYCPWKLCPLLPILYGRNKSVQNAWSCHKLHRFIDFPTPSANMNFFFFIRVCYGTVSLFISTFLKKISFFIYVNFTVYF
SIO_010081: YCR001W
subclass of: SO_0000673
so part of: YCR001W
location: 115685..115999
location: region:115685-115999:1
so has part: feature:115685-115999:1:exon

NP_001335748.1
type: Protein
SIO_000068: ncbiprotein

S000000594
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:115685-115999:1:exon

YCR002C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CDC10
locus tag: YCR002C
so part of: sequence
location: complement(<117380..>118348)
location: region:117380-118348:-1
so has part: feature:117380-118348:-1:exon
subclass of: SO_0000010

850358
type: Gene
SIO_000068: ncbigene

position:117380:-1
position: 117380
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:118348:-1
position: 118348
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:117380-118348:-1:exon

YCR002C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CDC10
locus tag: YCR002C
product: septin CDC10
transcript id: NM_001178715.1
SIO_010081: YCR002C
subclass of: SO_0000673
so part of: YCR002C
location: complement(<117380..>118348)
location: region:117380-118348:-1
so has part: feature:117380-118348:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:117380-118348:-1:exon

YCR002C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CDC10
locus tag: YCR002C
experiment: EXISTENCE:curator inference:GO:0030011 maintenance of cell polarity [PMID:10882120]
experiment: EXISTENCE:direct assay:GO:0000144 cellular bud neck septin ring [PMID:9884239|PMID:31990274]
experiment: EXISTENCE:direct assay:GO:0001400 mating projection base [PMID:18552279]
experiment: EXISTENCE:direct assay:GO:0003924 GTPase activity [PMID:14993234]
experiment: EXISTENCE:direct assay:GO:0005200 structural constituent of cytoskeleton [PMID:18550837|PMID:22144691|PMID:29321251]
experiment: EXISTENCE:direct assay:GO:0005545 1-phosphatidylinositol binding [PMID:12665577]
experiment: EXISTENCE:direct assay:GO:0005628 prospore membrane [PMID:18826657|PMID:24390141]
experiment: EXISTENCE:direct assay:GO:0005876 spindle microtubule [PMID:18826657]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0010314 phosphatidylinositol-5-phosphate binding [PMID:12665577]
experiment: EXISTENCE:direct assay:GO:0031105 septin complex [PMID:18550837]
experiment: EXISTENCE:direct assay:GO:0032160 septin filament array [PMID:15282341]
experiment: EXISTENCE:direct assay:GO:0042764 ascospore-type prospore [PMID:18701287]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:19053807]
experiment: EXISTENCE:direct assay:GO:0043934 sporulation [PMID:18701287]
experiment: EXISTENCE:direct assay:GO:0060090 molecular adaptor activity [PMID:15901837]
experiment: EXISTENCE:direct assay:GO:0070273 phosphatidylinositol-4-phosphate binding [PMID:12665577]
experiment: EXISTENCE:direct assay:GO:0072687 meiotic spindle [PMID:18826657]
experiment: EXISTENCE:mutant phenotype:GO:0000281 mitotic cytokinesis [PMID:4950437]
experiment: EXISTENCE:mutant phenotype:GO:0000921 septin ring assembly [PMID:14993234]
experiment: EXISTENCE:mutant phenotype:GO:0010458 exit from mitosis [PMID:12699621]
experiment: EXISTENCE:physical interaction:GO:0031105 septin complex [PMID:9813094]
note: Component of the septin ring, required for cytokinesis; septins are GTP-binding proteins that assemble into rod-like hetero-oligomers that can associate to form filaments; septin rings at the mother-bud neck act as scaffolds for recruiting cell division factors and as barriers to prevent diffusion of specific proteins between mother and daughter cells; N-terminus interacts with phosphatidylinositol-4,5-bisphosphate; protein abundance increases under DNA damage stress
codon start: 1
product: septin CDC10
translation: MDPLSSVQPASYVGFDTITNQIEHRLLKKGFQFNIMVVGQSGLGKSTLINTLFASHLIDSATGDDISALPVTKTTEMKISTHTLVEDRVRLNINVIDTPGFGDFIDNSKAWEPIVKYIKEQHSQYLRKELTAQRERFITDTRVHAILYFLQPNGKELSRLDVEALKRLTEIANVIPVIGKSDTLTLDERTEFRELIQNEFEKYNFKIYPYDSEELTDEELELNRSVRSIIPFAVVGSENEIEINGETFRGRKTRWSAINVEDINQCDFVYLREFLIRTHLQDLIETTSYIHYEGFRARQLIALKENANSRSSAHMSSNAIQR
SIO_010081: YCR002C
subclass of: SO_0000673
so part of: YCR002C
location: complement(117380..118348)
location: region:117380-118348:-1
so has part: feature:117380-118348:-1:exon

NP_009928.1
type: Protein
SIO_000068: ncbiprotein

S000000595
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:117380-118348:-1:exon

YCR003W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: bL32m
gene: MRPL32
locus tag: YCR003W
gene synonym: bL32m
so part of: sequence
location: <118620..>119171
location: region:118620-119171:1
so has part: feature:118620-119171:1:exon
subclass of: SO_0000010

850359
type: Gene
SIO_000068: ncbigene

position:118620:1
position: 118620
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:119171:1
position: 119171
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:118620-119171:1:exon

YCR003W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: bL32m
gene: MRPL32
locus tag: YCR003W
gene synonym: bL32m
product: mitochondrial 54S ribosomal protein YmL32
transcript id: NM_001178716.1
SIO_010081: YCR003W
subclass of: SO_0000673
so part of: YCR003W
location: <118620..>119171
location: region:118620-119171:1
so has part: feature:118620-119171:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:118620-119171:1:exon

YCR003W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: bL32m
gene: MRPL32
locus tag: YCR003W
gene synonym: bL32m
experiment: EXISTENCE:curator inference:GO:0032543 mitochondrial translation [PMID:2060626]
experiment: EXISTENCE:direct assay:GO:0003735 structural constituent of ribosome [PMID:2060626]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:24769239|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005762 mitochondrial large ribosomal subunit [PMID:2060626]
note: Mitochondrial ribosomal protein of the large subunit; protein abundance increases in response to DNA replication stress
codon start: 1
product: mitochondrial 54S ribosomal protein YmL32
translation: MNSLIFGKQLAFHKIVPTTAIGWLVPLGNPSLQIPGQKQLGSIHRWLREKLQQDHKDTEDKDFFSNNGILLAVPKKKVSHQKKRQKLYGPGKKQLKMIHHLNKCPSCGHYKRANTLCMYCVGQISHIWKTHTAKEEIKPRQEEELSELDQRVLYPGRRDTKYTKDLKDKDNYLERRVRTLKKD
SIO_010081: YCR003W
subclass of: SO_0000673
so part of: YCR003W
location: 118620..119171
location: region:118620-119171:1
so has part: feature:118620-119171:1:exon

NP_009929.1
type: Protein
SIO_000068: ncbiprotein

S000000596
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:118620-119171:1:exon

YCR004C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: YCP4
locus tag: YCR004C
so part of: sequence
location: complement(<119575..>120318)
location: region:119575-120318:-1
so has part: feature:119575-120318:-1:exon
subclass of: SO_0000010

850360
type: Gene
SIO_000068: ncbigene

position:119575:-1
position: 119575
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:120318:-1
position: 120318
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:119575-120318:-1:exon

YCR004C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: YCP4
locus tag: YCR004C
product: flavodoxin-like fold family protein
transcript id: NM_001178717.1
SIO_010081: YCR004C
subclass of: SO_0000673
so part of: YCR004C
location: complement(<119575..>120318)
location: region:119575-120318:-1
so has part: feature:119575-120318:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:119575-120318:-1:exon

YCR004C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: YCP4
locus tag: YCR004C
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:21442317|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:14576278|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:16622836]
experiment: EXISTENCE:direct assay:GO:0032126 eisosome [PMID:19064668]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
note: hypothetical protein; has sequence and structural similarity to flavodoxins; predicted to be palmitoylated; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
codon start: 1
product: flavodoxin-like fold family protein
translation: MVKIAIITYSTYGHIDVLAQAVKKGVEAAGGKADIYRVEETLPDEVLTKMNAPQKPEDIPVATEKTLLEYDAFLFGVPTRFGNLPAQWSAFWDKTGGLWAKGSLNGKAAGIFVSTSSYGGGQESTVKACLSYLAHHGIIFLPLGYKNSFAELASIEEVHGGSPWGAGTLAGPDGSRTASPLELRIAEIQGKTFYETAKKLFPAKEAKPSTEKKTTTSDAAKRQTKPAAATTAEKKEDKGLLSCCTVM
SIO_010081: YCR004C
subclass of: SO_0000673
so part of: YCR004C
location: complement(119575..120318)
location: region:119575-120318:-1
so has part: feature:119575-120318:-1:exon

NP_009930.1
type: Protein
SIO_000068: ncbiprotein

S000000597
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:119575-120318:-1:exon

YCR005C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CIT2
locus tag: YCR005C
so part of: sequence
location: complement(<120946..>122328)
location: region:120946-122328:-1
so has part: feature:120946-122328:-1:exon
subclass of: SO_0000010

850361
type: Gene
SIO_000068: ncbigene

position:120946:-1
position: 120946
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:122328:-1
position: 122328
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:120946-122328:-1:exon

YCR005C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CIT2
locus tag: YCR005C
product: citrate (Si)-synthase CIT2
transcript id: NM_001178718.1
SIO_010081: YCR005C
subclass of: SO_0000673
so part of: YCR005C
location: complement(<120946..>122328)
location: region:120946-122328:-1
so has part: feature:120946-122328:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:120946-122328:-1:exon

YCR005C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CIT2
locus tag: YCR005C
EC number: 2.3.3.16
experiment: EXISTENCE:direct assay:GO:0004108 citrate (Si)-synthase activity [PMID:2181273]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:25982115]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005777 peroxisome [PMID:16877773|PMID:25982115]
experiment: EXISTENCE:genetic interaction:GO:0004108 citrate (Si)-synthase activity [PMID:2181273]
experiment: EXISTENCE:genetic interaction:GO:0006101 citrate metabolic process [PMID:12913175]
note: Citrate synthase, peroxisomal isozyme involved in glyoxylate cycle; catalyzes condensation of acetyl coenzyme A and oxaloacetate to form citrate; expression is controlled by Rtg1p and Rtg2p transcription factors; SCF-Ucc1 regulates level of Cit2p to maintain citrate homeostasis; oxaloacetate-dependent positive feedback loop inhibits Cit2p ubiquitination; CIT2 has a paralog, CIT1, that arose from the whole genome duplication
codon start: 1
product: citrate (Si)-synthase CIT2
translation: MTVPYLNSNRNVASYLQSNSSQEKTLKERFSEIYPIHAQDVRQFVKEHGKTKISDVLLEQVYGGMRGIPGSVWEGSVLDPEDGIRFRGRTIADIQKDLPKAKGSSQPLPEALFWLLLTGEVPTQAQVENLSADLMSRSELPSHVVQLLDNLPKDLHPMAQFSIAVTALESESKFAKAYAQGISKQDYWSYTFEDSLDLLGKLPVIAAKIYRNVFKDGKMGEVDPNADYAKNLVNLIGSKDEDFVDLMRLYLTIHSDHEGGNVSAHTSHLVGSALSSPYLSLASGLNGLAGPLHGRANQEVLEWLFALKEEVNDDYSKDTIEKYLWDTLNSGRVIPGYGHAVLRKTDPRYMAQRKFAMDHFPDYELFKLVSSIYEVAPGVLTEHGKTKNPWPNVDAHSGVLLQYYGLKESSFYTVLFGVSRAFGILAQLITDRAIGASIERPKSYSTEKYKELVKNIESKL
SIO_010081: YCR005C
subclass of: SO_0000673
so part of: YCR005C
location: complement(120946..122328)
location: region:120946-122328:-1
so has part: feature:120946-122328:-1:exon

NP_009931.1
type: Protein
SIO_000068: ncbiprotein

S000000598
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:120946-122328:-1:exon

YCR006C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCR006C
so part of: sequence
location: complement(<122530..>123003)
location: region:122530-123003:-1
so has part: feature:122530-123003:-1:exon
subclass of: SO_0000010

850362
type: Gene
SIO_000068: ncbigene

position:122530:-1
position: 122530
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:123003:-1
position: 123003
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:122530-123003:-1:exon

YCR006C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCR006C
product: uncharacterized protein
transcript id: NM_001348894.1
SIO_010081: YCR006C
subclass of: SO_0000673
so part of: YCR006C
location: complement(<122530..>123003)
location: region:122530-123003:-1
so has part: feature:122530-123003:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:122530-123003:-1:exon

YCR006C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YCR006C
note: hypothetical protein; conserved among S. cerevisiae strains; YCR006C is not an essential gene
codon start: 1
product: uncharacterized protein
translation: MFIRVCNRLIYTPTNVLLITVEDGRISVLLWFRYAIPAELCYTRLARILRGKHCADFPQSCCHNISRFGVLNKSVLGSFNQWLGGISKERKLIARTFDAFIRWSSTRGEEVTTYFFLQKKSVTFSVARRLSGRQQWEAQRKNNNNGKRNYLLSVTFV
SIO_010081: YCR006C
subclass of: SO_0000673
so part of: YCR006C
location: complement(122530..123003)
location: region:122530-123003:-1
so has part: feature:122530-123003:-1:exon

NP_001335749.1
type: Protein
SIO_000068: ncbiprotein

S000000599
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:122530-123003:-1:exon

YNCC0004C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SUF2
locus tag: YNCC0004C
so part of: sequence
location: complement(123577..123648)
location: region:123577-123648:-1
so has part: feature:123577-123648:-1:exon
subclass of: SO_0000663

850363
type: Gene
SIO_000068: ncbigene

position:123577:-1
position: 123577
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:123648:-1
position: 123648
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:123577-123648:-1:exon

YNCC0004C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
gene: SUF2
locus tag: YNCC0004C
product: tRNA-Pro
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Proline tRNA (tRNA-Pro), predicted by tRNAscan-SE analysis; can mutate to suppress +1 frameshift mutations in proline codons
SIO_010081: YNCC0004C
subclass of: SO_0000673
so part of: YNCC0004C
location: complement(123577..123648)
location: region:123577-123648:-1
so has part: feature:123577-123648:-1:exon

S000006678
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:123577-123648:-1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(124134..124465)
location: region:124134-124465:-1
so has part: feature:124134-124465:-1:region

S000006832
type: SGD
SIO_000068: sgd

position:124134:-1
position: 124134
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:124465:-1
position: 124465
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:124134-124465:-1:region

YCR007C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCR007C
so part of: sequence
location: complement(<126011..>126730)
location: region:126011-126730:-1
so has part: feature:126011-126730:-1:exon
subclass of: SO_0000010

850364
type: Gene
SIO_000068: ncbigene

position:126011:-1
position: 126011
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:126730:-1
position: 126730
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:126011-126730:-1:exon

YCR007C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCR007C
product: DUP240 family protein
transcript id: NM_001178720.1
SIO_010081: YCR007C
subclass of: SO_0000673
so part of: YCR007C
location: complement(<126011..>126730)
location: region:126011-126730:-1
so has part: feature:126011-126730:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:126011-126730:-1:exon

YCR007C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YCR007C
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
note: Putative integral membrane protein; member of DUP240 gene family; SWAT-GFP and mCherry fusion proteins localize to the cell periphery and vacuole; YCR007C is not an essential gene
codon start: 1
product: DUP240 family protein
translation: MQPHLDNNSNNDDVKLDTLGEQNVLSSAENITLPEDTFKSYMTYLLYEMAHYKPMIFSFLALSVSILIVVIFHNVKACDVVFGFSIFVTSILFLSTLIPFNVYISDEGFRIKLLLEVITHRPAVKGKEWRAITDNMNQYLLDNGLWSTRYYFYSSERCYKFFRFLVKEKPPGVNVNSSVKDATSTQIDAPANEASNEVIKCFSFSSDPIFEAYFVKAVEVEKQAQQEYWRKQYPDADIP
SIO_010081: YCR007C
subclass of: SO_0000673
so part of: YCR007C
location: complement(126011..126730)
location: region:126011-126730:-1
so has part: feature:126011-126730:-1:exon

NP_009933.1
type: Protein
SIO_000068: ncbiprotein

S000000600
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:126011-126730:-1:exon

YNCC0005W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCC0005W
so part of: sequence
location: 127716..127789
location: region:127716-127789:1
so has part: feature:127716-127789:1:exon
subclass of: SO_0000663

850365
type: Gene
SIO_000068: ncbigene

position:127716:1
position: 127716
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:127789:1
position: 127789
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:127716-127789:1:exon

YNCC0005W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCC0005W
product: tRNA-Asn
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Asparagine tRNA (tRNA-Asn), predicted by tRNAscan-SE analysis
SIO_010081: YNCC0005W
subclass of: SO_0000673
so part of: YNCC0005W
location: 127716..127789
location: region:127716-127789:1
so has part: feature:127716-127789:1:exon

S000006668
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:127716-127789:1:exon

YCR008W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: HAL4
gene: SAT4
locus tag: YCR008W
gene synonym: HAL4
so part of: sequence
location: <128470..>130281
location: region:128470-130281:1
so has part: feature:128470-130281:1:exon
subclass of: SO_0000010

850366
type: Gene
SIO_000068: ncbigene

position:128470:1
position: 128470
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:130281:1
position: 130281
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:128470-130281:1:exon

YCR008W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: HAL4
gene: SAT4
locus tag: YCR008W
gene synonym: HAL4
product: serine/threonine protein kinase SAT4
transcript id: NM_001178721.1
SIO_010081: YCR008W
subclass of: SO_0000673
so part of: YCR008W
location: <128470..>130281
location: region:128470-130281:1
so has part: feature:128470-130281:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:128470-130281:1:exon

YCR008W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: HAL4
gene: SAT4
locus tag: YCR008W
gene synonym: HAL4
EC number: 2.7.11.1
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:16319894]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:25117470]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:25117470]
experiment: EXISTENCE:genetic interaction:GO:0000082 G1/S transition of mitotic cell cycle [PMID:12518319]
experiment: EXISTENCE:genetic interaction:GO:0008104 protein localization [PMID:21237705]
experiment: EXISTENCE:mutant phenotype:GO:0009249 protein lipoylation [PMID:25117470]
experiment: EXISTENCE:mutant phenotype:GO:0009594 detection of nutrient [PMID:32191698]
experiment: EXISTENCE:mutant phenotype:GO:0030003 cellular cation homeostasis [PMID:10207057]
experiment: EXISTENCE:mutant phenotype:GO:0045807 positive regulation of endocytosis [PMID:32191698]
experiment: EXISTENCE:mutant phenotype:GO:1903329 regulation of iron-sulfur cluster assembly [PMID:25117470]
note: Ser/Thr protein kinase involved in salt tolerance, nutrient response; functions in regulation of Trk1p-Trk2p potassium transporter; overexpression affects the Fe-S and lipoamide containing proteins in the mitochondrion; required for lipoylation of Lat1p, Kgd2p and Gcv3p; partially redundant with Hal5p; has similarity to Npr1p; localizes to the cytoplasm and mitochondrion
codon start: 1
product: serine/threonine protein kinase SAT4
translation: MTGMNDNNAAIPQQTPRKHALSSKVMQLFRSGSRSSRQGKASSNIQPPSNINTNVPSASKSAKFGLHTPTTATPRVVSNPSNTAGVSKPGMYMPEYYQSASPSHSSSSASLNNHIDINTSKSSSAASLTSSVSALSLSPTSAINISSKSLSPKFSHHSNSNTAITPAPTPTASNINNVNKITNTSAPICGRFLVHKDGTHEHHLKNAKRQEKLSTMIKNMVGASKLRGEAKSAVPDIIMDPKTTLKSNKNPPTLFAGFMKQVVDMDDKYPEGAPTSGALNCPERDIYRSDQKDSKNNTHNITTTKKDRQCFAEKYGRCQEVLGKGAFGVVRICQKKNVSSQDGNKSEKLYAVKEFKRRTSESAEKYSKRLTSEFCISSSLHHTNIVTTLDLFQDAKGEYCEVMEYCAGGDLFTLVVAAGKLEYMEADCFFKQLIRGVVYMHEMGVCHRDLKPENLLLTHDGVLKITDFGNSECFKMAWEKNIHLSGGVCGSSPYIAPEEYIKEEFDPRPVDIWACGVIYMAMRTGRQLWSSAEKDDPFYMNYLKGRKEKGGYEPIESLKRARCRNVIYSMLDPVPYRRINGKQILNSEWGREIKCCHNGRALK
SIO_010081: YCR008W
subclass of: SO_0000673
so part of: YCR008W
location: 128470..130281
location: region:128470-130281:1
so has part: feature:128470-130281:1:exon

NP_009934.1
type: Protein
SIO_000068: ncbiprotein

S000000601
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:128470-130281:1:exon

YCR009C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: END6
alternative label: FUS7
alternative label: SPE161
gene: RVS161
locus tag: YCR009C
gene synonym: END6; FUS7; SPE161
so part of: sequence
location: complement(<130745..>131542)
location: region:130745-131542:-1
so has part: feature:130745-131542:-1:exon
subclass of: SO_0000010

850367
type: Gene
SIO_000068: ncbigene

position:130745:-1
position: 130745
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:131542:-1
position: 131542
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:130745-131542:-1:exon

YCR009C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: END6
alternative label: FUS7
alternative label: SPE161
gene: RVS161
locus tag: YCR009C
gene synonym: END6; FUS7; SPE161
product: amphiphysin-like protein RVS161
transcript id: NM_001178722.1
SIO_010081: YCR009C
subclass of: SO_0000673
so part of: YCR009C
location: complement(<130745..>131542)
location: region:130745-131542:-1
so has part: feature:130745-131542:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:130745-131542:-1:exon

YCR009C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: END6
alternative label: FUS7
alternative label: SPE161
gene: RVS161
locus tag: YCR009C
gene synonym: END6; FUS7; SPE161
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005937 mating projection [PMID:9566960]
experiment: EXISTENCE:direct assay:GO:0008289 lipid binding [PMID:20610658|PMID:27093085]
experiment: EXISTENCE:direct assay:GO:0030479 actin cortical patch [PMID:16239147]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:19053807]
experiment: EXISTENCE:direct assay:GO:0045121 membrane raft [PMID:12477802]
experiment: EXISTENCE:direct assay:GO:0060988 lipid tube assembly [PMID:20610658]
experiment: EXISTENCE:direct assay:GO:0097320 plasma membrane tubulation [PMID:27093085]
experiment: EXISTENCE:mutant phenotype:GO:0000747 conjugation with cellular fusion [PMID:11096097]
experiment: EXISTENCE:mutant phenotype:GO:0006897 endocytosis [PMID:8590801]
experiment: EXISTENCE:mutant phenotype:GO:0006970 response to osmotic stress [PMID:1776363]
experiment: EXISTENCE:mutant phenotype:GO:0030036 actin cytoskeleton organization [PMID:7891662]
experiment: EXISTENCE:mutant phenotype:GO:0031532 actin cytoskeleton reorganization [PMID:7891662]
experiment: EXISTENCE:mutant phenotype:GO:0042594 response to starvation [PMID:1776363]
experiment: EXISTENCE:mutant phenotype:GO:0051666 actin cortical patch localization [PMID:8590801]
experiment: EXISTENCE:physical interaction:GO:0008092 cytoskeletal protein binding [PMID:10388809]
experiment: EXISTENCE:physical interaction:GO:1990528 Rvs161p-Rvs167p complex [PMID:20610658]
note: Amphiphysin-like lipid raft protein; N-BAR domain protein that interacts with Rvs167p and regulates polarization of the actin cytoskeleton, endocytosis, cell polarity, cell fusion and viability following starvation or osmotic stress
codon start: 1
product: amphiphysin-like protein RVS161
translation: MSWEGFKKAINRAGHSVIIKNVDKTIDKEYDMEERRYKVLQRAGEALQKEAKGFLDSLRAVTASQTTIAEVISNLYDDSKYVAGGGYNVGNYYLQCVQDFDSETVKQLDGPLRETVLDPITKFSTYFKEIEEAIKKRDHKKQDFDAAKAKVRRLVDKPAKDASKLPRAEKELSLAKDIFENLNNQLKTELPQLVSLRVPYFDPSFEALIKIQLRFCTDGYTRLAQIQQYLDQQSRDDYANGLLDTKIEELLGQMTSLDICALGIK
SIO_010081: YCR009C
subclass of: SO_0000673
so part of: YCR009C
location: complement(130745..131542)
location: region:130745-131542:-1
so has part: feature:130745-131542:-1:exon

NP_009935.1
type: Protein
SIO_000068: ncbiprotein

S000000602
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:130745-131542:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS309; Autonomously Replicating Sequence on Chromosome III
so part of: sequence
location: 132043..132120
location: region:132043-132120:1
so has part: feature:132043-132120:1:region

S000028486
type: SGD
SIO_000068: sgd

position:132043:1
position: 132043
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:132120:1
position: 132120
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:132043-132120:1:region

YCR010C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ATO1
gene: ADY2
locus tag: YCR010C
gene synonym: ATO1
so part of: sequence
location: complement(<132273..>133124)
location: region:132273-133124:-1
so has part: feature:132273-133124:-1:exon
subclass of: SO_0000010

850368
type: Gene
SIO_000068: ncbigene

position:132273:-1
position: 132273
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:133124:-1
position: 133124
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:132273-133124:-1:exon

YCR010C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ATO1
gene: ADY2
locus tag: YCR010C
gene synonym: ATO1
product: Ady2p
transcript id: NM_001178723.1
SIO_010081: YCR010C
subclass of: SO_0000673
so part of: YCR010C
location: complement(<132273..>133124)
location: region:132273-133124:-1
so has part: feature:132273-133124:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:132273-133124:-1:exon

YCR010C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ATO1
gene: ADY2
locus tag: YCR010C
gene synonym: ATO1
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:17395151|PMID:16622836]
experiment: EXISTENCE:mutant phenotype:GO:0006846 acetate transport [PMID:14968426]
experiment: EXISTENCE:mutant phenotype:GO:0008519 ammonium transmembrane transporter activity [PMID:12429834]
experiment: EXISTENCE:mutant phenotype:GO:0015123 acetate transmembrane transporter activity [PMID:14968426]
experiment: EXISTENCE:mutant phenotype:GO:0019740 nitrogen utilization [PMID:12429834]
experiment: EXISTENCE:mutant phenotype:GO:0055085 transmembrane transport [PMID:14968426]
experiment: EXISTENCE:mutant phenotype:GO:0072488 ammonium transmembrane transport [PMID:12429834]
note: Acetate transporter required for normal sporulation; phosphorylated in mitochondria; ADY2 has a paralog, ATO2, that arose from the whole genome duplication
codon start: 1
product: Ady2p
translation: MSDKEQTSGNTDLENAPAGYYSSHDNDVNGVAEDERPSHDSLGKIYTGGDNNEYIYIGRQKFLKSDLYQAFGGTLNPGLAPAPVHKFANPAPLGLSAFALTTFVLSMFNARAQGITVPNVVVGCAMFYGGLVQLIAGIWEIALENTFGGTALCSYGGFWLSFAAIYIPWFGILEAYEDNESDLNNALGFYLLGWAIFTFGLTVCTMKSTVMFFLLFFLLALTFLLLSIGHFANRLGVTRAGGVLGVVVAFIAWYNAYAGVATKQNSYVLARPFPLPSTERVIF
SIO_010081: YCR010C
subclass of: SO_0000673
so part of: YCR010C
location: complement(132273..133124)
location: region:132273-133124:-1
so has part: feature:132273-133124:-1:exon

NP_009936.1
type: Protein
SIO_000068: ncbiprotein

S000000603
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:132273-133124:-1:exon

YCR011C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ADP1
locus tag: YCR011C
so part of: sequence
location: complement(<133724..>136873)
location: region:133724-136873:-1
so has part: feature:133724-136873:-1:exon
subclass of: SO_0000010

850369
type: Gene
SIO_000068: ncbigene

position:133724:-1
position: 133724
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:136873:-1
position: 136873
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:133724-136873:-1:exon

YCR011C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ADP1
locus tag: YCR011C
product: putative ATP-dependent permease ADP1
transcript id: NM_001178724.1
SIO_010081: YCR011C
subclass of: SO_0000673
so part of: YCR011C
location: complement(<133724..>136873)
location: region:133724-136873:-1
so has part: feature:133724-136873:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:133724-136873:-1:exon

YCR011C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ADP1
locus tag: YCR011C
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:19001347]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:11914276]
note: Putative ATP-dependent permease of the ABC transporter family
codon start: 1
product: putative ATP-dependent permease ADP1
translation: MGSHRRYLYYSILSFLLLSCSVVLAKQDKTPFFEGTSSKNSRLTAQDKGNDTCPPCFNCMLPIFECKQFSECNSYTGRCECIEGFAGDDCSLPLCGGLSPDESGNKDRPIRAQNDTCHCDNGWGGINCDVCQEDFVCDAFMPDPSIKGTCYKNGMIVDKVFSGCNVTNEKILQILNGKIPQITFACDKPNQECNFQFWIDQLESFYCGLSDCAFEYDLEQNTSHYKCNDVQCKCVPDTVLCGAKGSIDISDFLTETIKGPGDFSCDLETRQCKFSEPSMNDLILTVFGDPYITLKCESGECVHYSEIPGYKSPSKDPTVSWQGKLVLALTAVMVLALFTFATFYISKSPLFRNGLGSSKSPIRLPDEDAVNNFLQNEDDTLATLSFENITYSVPSINSDGVEETVLNEISGIVKPGQILAIMGGSGAGKTTLLDILAMKRKTGHVSGSIKVNGISMDRKSFSKIIGFVDQDDFLLPTLTVFETVLNSALLRLPKALSFEAKKARVYKVLEELRIIDIKDRIIGNEFDRGISGGEKRRVSIACELVTSPLVLFLDEPTSGLDASNANNVIECLVRLSSDYNRTLVLSIHQPRSNIFYLFDKLVLLSKGEMVYSGNAKKVSEFLRNEGYICPDNYNIADYLIDITFEAGPQGKRRRIRNISDLEAGTDTNDIDNTIHQTTFTSSDGTTQREWAHLAAHRDEIRSLLRDEEDVEGTDGRRGATEIDLNTKLLHDKYKDSVYYAELSQEIEEVLSEGDEESNVLNGDLPTGQQSAGFLQQLSILNSRSFKNMYRNPKLLLGNYLLTILLSLFLGTLYYNVSNDISGFQNRMGLFFFILTYFGFVTFTGLSSFALERIIFIKERSNNYYSPLAYYISKIMSEVVPLRVVPPILLSLIVYPMTGLNMKDNAFFKCIGILILFNLGISLEILTIGIIFEDLNNSIILSVLVLLGSLLFSGLFINTKNITNVAFKYLKNFSVFYYAYESLLINEVKTLMLKERKYGLNIEVPGATILSTFGFVVQNLVFDIKILALFNVVFLIMGYLALKWIVVEQK
SIO_010081: YCR011C
subclass of: SO_0000673
so part of: YCR011C
location: complement(133724..136873)
location: region:133724-136873:-1
so has part: feature:133724-136873:-1:exon

NP_009937.2
type: Protein
SIO_000068: ncbiprotein

S000000604
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:133724-136873:-1:exon

YCR012W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PGK1
locus tag: YCR012W
so part of: sequence
location: <137746..>138996
location: region:137746-138996:1
so has part: feature:137746-138996:1:exon
subclass of: SO_0000010

850370
type: Gene
SIO_000068: ncbigene

position:137746:1
position: 137746
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:138996:1
position: 138996
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:137746-138996:1:exon

YCR012W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PGK1
locus tag: YCR012W
product: phosphoglycerate kinase
transcript id: NM_001178725.1
SIO_010081: YCR012W
subclass of: SO_0000673
so part of: YCR012W
location: <137746..>138996
location: region:137746-138996:1
so has part: feature:137746-138996:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:137746-138996:1:exon

YCR012W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PGK1
locus tag: YCR012W
EC number: 2.7.2.3
experiment: EXISTENCE:direct assay:GO:0004618 phosphoglycerate kinase activity [PMID:6254992]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:27385335|PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16962558|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:16622836]
experiment: EXISTENCE:mutant phenotype:GO:0006094 gluconeogenesis [PMID:400791]
experiment: EXISTENCE:mutant phenotype:GO:0006096 glycolytic process [PMID:400791]
note: 3-phosphoglycerate kinase; catalyzes transfer of high-energy phosphoryl groups from the acyl phosphate of 1,3-bisphosphoglycerate to ADP to produce ATP; key enzyme in glycolysis and gluconeogenesis
codon start: 1
product: phosphoglycerate kinase
translation: MSLSSKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHLGRPNGERNEKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLRYHIEEEGSRKVDGQKVKASKEDVQKFRHELSSLADVYINDAFGTAHRAHSSMVGFDLPQRAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMAFTFKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTDKEGIPAGWQGLDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSSAAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLELLEGKELPGVAFLSEKK
SIO_010081: YCR012W
subclass of: SO_0000673
so part of: YCR012W
location: 137746..138996
location: region:137746-138996:1
so has part: feature:137746-138996:1:exon

NP_009938.2
type: Protein
SIO_000068: ncbiprotein

S000000605
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:137746-138996:1:exon

YCR014C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: POL4
locus tag: YCR014C
so part of: sequence
location: complement(<139185..>140933)
location: region:139185-140933:-1
so has part: feature:139185-140933:-1:exon
subclass of: SO_0000010

850372
type: Gene
SIO_000068: ncbigene

position:139185:-1
position: 139185
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:140933:-1
position: 140933
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:139185-140933:-1:exon

YCR014C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: POL4
locus tag: YCR014C
product: DNA-directed DNA polymerase IV
transcript id: NM_001178727.1
SIO_010081: YCR014C
subclass of: SO_0000673
so part of: YCR014C
location: complement(<139185..>140933)
location: region:139185-140933:-1
so has part: feature:139185-140933:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:139185-140933:-1:exon

YCR014C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: POL4
locus tag: YCR014C
EC number: 2.7.7.7
experiment: EXISTENCE:curator inference:GO:0005634 nucleus [PMID:8265341]
experiment: EXISTENCE:direct assay:GO:0003887 DNA-directed DNA polymerase activity [PMID:8265341]
experiment: EXISTENCE:direct assay:GO:0006302 double-strand break repair [PMID:12235149]
experiment: EXISTENCE:direct assay:GO:0006303 double-strand break repair via nonhomologous end joining [PMID:10438542|PMID:15342630]
experiment: EXISTENCE:mutant phenotype:GO:0006303 double-strand break repair via nonhomologous end joining [PMID:10438542]
note: DNA polymerase IV; undergoes pair-wise interactions with Dnl4p-Lif1p and Rad27p to mediate repair of DNA double-strand breaks by non-homologous end joining (NHEJ); homologous to mammalian DNA polymerase beta
codon start: 1
product: DNA-directed DNA polymerase IV
translation: MSLKGKFFAFLPNPNTSSNKFFKSILEKKGATIVSSIQNCLQSSRKEVVILIEDSFVDSDMHLTQKDIFQREAGLNDVDEFLGKIEQSGIQCVKTSCITKWVQNDKFAFQKDDLIKFQPSIIVISDNADDGQSSTDKESEISTDVESERNDDSNNKDMIQASKPLKRLLQGDKGRASLVTDKTKYKNNELIIGALKRLTKKYEIEGEKFRARSYRLAKQSMENCDFNVRSGEEAHTKLRNIGPSIAKKIQVILDTGVLPGLNDSVGLEDKLKYFKNCYGIGSEIAKRWNLLNFESFCVAAKKDPEEFVSDWTILFGWSYYDDWLCKMSRNECFTHLKKVQKALRGIDPECQVELQGSYNRGYSKCGDIDLLFFKPFCNDTTELAKIMETLCIKLYKDGYIHCFLQLTPNLEKLFLKRIVERFRTAKIVGYGERKRWYSSEIIKKFFMGVKLSPRELEELKEMKNDEGTLLIEEEEEEETKLKPIDQYMSLNAKDGNYCRRLDFFCCKWDELGAGRIHYTGSKEYNRWIRILAAQKGFKLTQHGLFRNNILLESFNERRIFELLNLKYAEPEHRNIEWEKKTA
SIO_010081: YCR014C
subclass of: SO_0000673
so part of: YCR014C
location: complement(139185..140933)
location: region:139185-140933:-1
so has part: feature:139185-140933:-1:exon

NP_009940.2
type: Protein
SIO_000068: ncbiprotein

S000000607
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:139185-140933:-1:exon

YCR015C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CTO1
locus tag: YCR015C
so part of: sequence
location: complement(<141217..>142170)
location: region:141217-142170:-1
so has part: feature:141217-142170:-1:exon
subclass of: SO_0000010

850373
type: Gene
SIO_000068: ncbigene

position:141217:-1
position: 141217
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:142170:-1
position: 142170
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:141217-142170:-1:exon

YCR015C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CTO1
locus tag: YCR015C
product: Cto1p
transcript id: NM_001178728.1
SIO_010081: YCR015C
subclass of: SO_0000673
so part of: YCR015C
location: complement(<141217..>142170)
location: region:141217-142170:-1
so has part: feature:141217-142170:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:141217-142170:-1:exon

YCR015C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CTO1
locus tag: YCR015C
experiment: EXISTENCE:direct assay:GO:0042131 thiamine phosphate phosphatase activity [PMID:26071590]
experiment: EXISTENCE:mutant phenotype:GO:0006817 phosphate ion transport [PMID:25725023]
note: Protein required for cold tolerance; involved in phosphate uptake; YCR015C is not an essential gene
codon start: 1
product: Cto1p
translation: MKTIIISDFDETITRVDTICTIAKLPYLLNPRLKPEWGHFTKTYMDGYHKYKYNGTRSLPLLSSGVPTIISQSNFNKLFADELKYQNHNRVVELNSVNEITKQQIFKSISLDQMKTFARDQNHEDCLLRDGFKTFCSSVVKNFESDFYVLSINWSKEFIHEVIGDRRLKNSHIFCNDLKKVSDKCSQSYNGEFDCRLLTGSDKVKILGEILDKIDSGCNKEGNSCSYWYIGDSETDLLSILHPSTNGVLLINPQENPSKFIKITEKIIGIPKDKISSFEADNGPAWLQFCEKEGGKGAYLVKSWDSLKDLIMQVTKM
SIO_010081: YCR015C
subclass of: SO_0000673
so part of: YCR015C
location: complement(141217..142170)
location: region:141217-142170:-1
so has part: feature:141217-142170:-1:exon

NP_009941.2
type: Protein
SIO_000068: ncbiprotein

S000000608
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:141217-142170:-1:exon

YNCC0006C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SNR33
locus tag: YNCC0006C
so part of: sequence
location: complement(142364..142546)
location: region:142364-142546:-1
so has part: feature:142364-142546:-1:exon
subclass of: SO_0000578

9164874
type: Gene
SIO_000068: ncbigene

position:142364:-1
position: 142364
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:142546:-1
position: 142546
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:142364-142546:-1:exon

YNCC0006C
type: Non Coding RNA
subclass of: SO_0000655
RO_0002162: 559292
nc RNA class: snoRNA
gene: SNR33
locus tag: YNCC0006C
product: SNR33
experiment: EXISTENCE:curator inference:GO:0005730 nucleolus [PMID:9160748]
experiment: EXISTENCE:mutant phenotype:GO:0030559 rRNA pseudouridylation guide activity [PMID:9160748]
experiment: EXISTENCE:mutant phenotype:GO:0031118 rRNA pseudouridine synthesis [PMID:9160748]
experiment: EXISTENCE:physical interaction:GO:0031429 box H/ACA snoRNP complex [PMID:15923376|PMID:9472021]
note: H/ACA box small nucleolar RNA (snoRNA); guides pseudouridylation of large subunit (LSU) rRNA at position U1042
transcript id: NR_132156.1
SIO_010081: YNCC0006C
subclass of: SO_0000673
so part of: YNCC0006C
location: complement(142364..142546)
location: region:142364-142546:-1
so has part: feature:142364-142546:-1:exon

S000007298
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:142364-142546:-1:exon

YNCC0007C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SUF16
locus tag: YNCC0007C
so part of: sequence
location: complement(142701..142771)
location: region:142701-142771:-1
so has part: feature:142701-142771:-1:exon
subclass of: SO_0000663

850374
type: Gene
SIO_000068: ncbigene

position:142701:-1
position: 142701
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:142771:-1
position: 142771
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:142701-142771:-1:exon

YNCC0007C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
gene: SUF16
locus tag: YNCC0007C
product: tRNA-Gly
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
experiment: EXISTENCE:direct assay:GO:0030371 translation repressor activity [PMID:27609601]
experiment: EXISTENCE:direct assay:GO:0043022 ribosome binding [PMID:27609601]
experiment: EXISTENCE:direct assay:GO:0043555 regulation of translation in response to stress [PMID:27609601]
note: Glycine tRNA (tRNA-Gly), predicted by tRNAscan-SE analysis;can mutate to suppress +1 frameshift mutations in glycine codons
SIO_010081: YNCC0007C
subclass of: SO_0000673
so part of: YNCC0007C
location: complement(142701..142771)
location: region:142701-142771:-1
so has part: feature:142701-142771:-1:exon

S000006575
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:142701-142771:-1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(142758..143080)
location: region:142758-143080:-1
so has part: feature:142758-143080:-1:region

S000006833
type: SGD
SIO_000068: sgd

position:142758:-1
position: 142758
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:143080:-1
position: 143080
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:142758-143080:-1:region

YCR016W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCR016W
so part of: sequence
location: <143634..>144506
location: region:143634-144506:1
so has part: feature:143634-144506:1:exon
subclass of: SO_0000010

850375
type: Gene
SIO_000068: ncbigene

position:143634:1
position: 143634
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:144506:1
position: 144506
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:143634-144506:1:exon

YCR016W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCR016W
product: uncharacterized protein
transcript id: NM_001178729.1
SIO_010081: YCR016W
subclass of: SO_0000673
so part of: YCR016W
location: <143634..>144506
location: region:143634-144506:1
so has part: feature:143634-144506:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:143634-144506:1:exon

YCR016W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YCR016W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:14562095]
note: hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus and nucleus; predicted to be involved in ribosome biogenesis
codon start: 1
product: uncharacterized protein
translation: MSENHVPAWKRIALKRQTISSGDESKEKGQSNLIDDDPLNITTHLSTGNLTKKEKKRIINGESKSSTKKGKRVSKPGTKKKEKLSKDEKNSKKNKILKDQLRYLIEFFRTKSESKFPTGILELESVKENYGDSLIKDEPSESGVVEVWKFSKQKQNWLIKHFFNLDEIPSVYNDLLLLYFRDLQGKSKEELISKCKGKLKQWNDYVEDQETKIKALIAEDKASEPINGEEKEEGEKDGNAEQGKQKEVQDEQEEVQMPNKELVQRSLKLLEIWKNDDSEQIELKNFFVDV
SIO_010081: YCR016W
subclass of: SO_0000673
so part of: YCR016W
location: 143634..144506
location: region:143634-144506:1
so has part: feature:143634-144506:1:exon

NP_009942.2
type: Protein
SIO_000068: ncbiprotein

S000000609
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:143634-144506:1:exon

YCR017C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CWH43
locus tag: YCR017C
so part of: sequence
location: complement(<144773..>147634)
location: region:144773-147634:-1
so has part: feature:144773-147634:-1:exon
subclass of: SO_0000010

850376
type: Gene
SIO_000068: ncbigene

position:144773:-1
position: 144773
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:147634:-1
position: 147634
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:144773-147634:-1:exon

YCR017C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CWH43
locus tag: YCR017C
product: Cwh43p
transcript id: NM_001178730.1
SIO_010081: YCR017C
subclass of: SO_0000673
so part of: YCR017C
location: complement(<144773..>147634)
location: region:144773-147634:-1
so has part: feature:144773-147634:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:144773-147634:-1:exon

YCR017C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CWH43
locus tag: YCR017C
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:11427965]
experiment: EXISTENCE:direct assay:GO:0005934 cellular bud tip [PMID:11427965]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:11427965]
experiment: EXISTENCE:mutant phenotype:GO:0006505 GPI anchor metabolic process [PMID:27462707]
experiment: EXISTENCE:mutant phenotype:GO:0006506 GPI anchor biosynthetic process [PMID:17714445|PMID:17761529]
experiment: EXISTENCE:mutant phenotype:GO:0031505 fungal-type cell wall organization [PMID:11427965]
note: GPI lipid remodelase; responsible for introducing ceramides into GPI anchors having a C26:0 fatty acid in sn-2 of the glycerol moiety; can also use lyso-GPI protein anchors and various base resistant lipids as substrates; contains 14-16 transmembrane segments and several putative glycosylation and phosphorylation sites; null mutation is synthetically lethal with pkc1 deletion
codon start: 1
product: Cwh43p
translation: MLIINGKIIPIAHTICAFSAFFAALVTGYSLHFHKIVTNAHYTYPDEWFPSVSATIGDRYPERSIFQILIALTAFPRFLLLLGHYYLNQSKVCFLVGVLRTVSCGGWVYITSTDDHDIHDIFMITYIVLTLPWDIMITRYSSPLTSKNKGLTATIFFGTLFPMIYWYIQHSVQQRAGAYSIYAYFEWSLILLDIAFDAFAYADFKKIDIVLAFNEKPGNTSFFQIRDSSPINYGEEKSSELQKSGEKKVEKEKPVARSATGSYFRFDSFFYLLTNIFNGFLFWSNVTSLLCSIWHFPLWYMGISGYEAAILGYLGPIFLYLPFVSEAFTQYGVLLGGIIAIGAYIVQMPELRLISVAVGTSITVATFVQNLRYITNAETSFSFALTWLLGLVASVILKMGFYTNNPTWVILDERNGGYNKTALVLTVLFGMLSPYVNSINFEGKRNAQAKSASLIGKLFLAVGFGSLLFGIHQLLTDSSTTIYWAWEGYNESHGPLPWPWGALTCTVMLFASLSSVKFMGKPLVPCLLLLISTAVLSARSITQWPKYIFGGLLYAIAMLWLVPSYFSALGQVQNIWVYVLSFSVYIIFVLAHVWVVAYAFVPMGWVLREKIETVLAFSSTFIIIGALTCKNLNIQLVTMGKKFFIYVFFFAVALLSLTARFVYDIRPTGIPQPYHPDSQLITAGIWTIHFGLDNDMWASEDRMINLIKDMELDVVGLLETDTQRITMGNRDLTSKLAHDLNMYADFGPGPNKHTWGCVLLSKFPIVNSTHHLLPSPVGELAPAIHATLQTYNDTLVDVFVFHSGQEEDEEDRRLQSNYMAKLMGNTTRPAILLSYLVVDPGEGNYNTYVSETSGMHDIDPSDDDRWCEYILYRGLRRTGYARVARGTITDTELQVGKFQVLSEQALVEHSDSMYEYGHMSEPEYEDMKFPDKFLGEGERGHFYHVFDEPRYYL
SIO_010081: YCR017C
subclass of: SO_0000673
so part of: YCR017C
location: complement(144773..147634)
location: region:144773-147634:-1
so has part: feature:144773-147634:-1:exon

NP_009943.2
type: Protein
SIO_000068: ncbiprotein

S000000610
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:144773-147634:-1:exon

YCR018C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SRD1
locus tag: YCR018C
so part of: sequence
location: complement(<148238..>148903)
location: region:148238-148903:-1
so has part: feature:148238-148903:-1:exon
subclass of: SO_0000010

850377
type: Gene
SIO_000068: ncbigene

position:148238:-1
position: 148238
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:148903:-1
position: 148903
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:148238-148903:-1:exon

YCR018C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SRD1
locus tag: YCR018C
product: Srd1p
transcript id: NM_001178731.1
SIO_010081: YCR018C
subclass of: SO_0000673
so part of: YCR018C
location: complement(<148238..>148903)
location: region:148238-148903:-1
so has part: feature:148238-148903:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:148238-148903:-1:exon

YCR018C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SRD1
locus tag: YCR018C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:genetic interaction:GO:0006364 rRNA processing [PMID:2179050]
note: Protein involved in the processing of pre-rRNA to mature rRNA; contains a C2/C2 zinc finger motif; srd1 mutation suppresses defects caused by the rrp1-1 mutation
codon start: 1
product: Srd1p
translation: MRYNNYDNSGSSFLTRVVKKSDMEKTLLLNREIDDWKSNDKKKAYKERGRVYASCSFIEVSFSQIRAVDVEKKIENAEQLRDLTRNIVKNKTSSLNEITPSKNRVTSACNSERRTTSQEANNLEGYHSCAQGTSRSASITKKYSKKTTSRPKREKRQTILPNGEIKECSKCKDTWTIQWRSGPDQNRELCSPCGLAYGKRLKKENEKKRQAADKRIDRNNP
SIO_010081: YCR018C
subclass of: SO_0000673
so part of: YCR018C
location: complement(148238..148903)
location: region:148238-148903:-1
so has part: feature:148238-148903:-1:exon

NP_009944.2
type: Protein
SIO_000068: ncbiprotein

S000000611
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:148238-148903:-1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 149482..149809
location: region:149482-149809:1
so has part: feature:149482-149809:1:region

S000006835
type: SGD
SIO_000068: sgd

position:149482:1
position: 149482
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:149809:1
position: 149809
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:149482-149809:1:region

YNCC0008W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCC0008W
so part of: sequence
location: 149920..149991
location: region:149920-149991:1
so has part: feature:149920-149991:1:exon
subclass of: SO_0000663

850378
type: Gene
SIO_000068: ncbigene

position:149920:1
position: 149920
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:149991:1
position: 149991
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:149920-149991:1:exon

YNCC0008W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCC0008W
product: tRNA-Met
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006413 translational initiation [PMID:9023104]
experiment: EXISTENCE:direct assay:GO:0016282 eukaryotic 43S preinitiation complex [PMID:12008673]
experiment: EXISTENCE:direct assay:GO:0033290 eukaryotic 48S preinitiation complex [PMID:17242201]
experiment: EXISTENCE:direct assay:GO:0071074 eukaryotic initiation factor eIF2 binding [PMID:14698289]
note: Methionine tRNA (tRNA-Met), predicted by tRNAscan-SE analysis
SIO_010081: YNCC0008W
subclass of: SO_0000673
so part of: YNCC0008W
location: 149920..149991
location: region:149920-149991:1
so has part: feature:149920-149991:1:exon

S000006658
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:149920-149991:1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 150220..150551
location: region:150220-150551:1
so has part: feature:150220-150551:1:region

S000006836
type: SGD
SIO_000068: sgd

position:150220:1
position: 150220
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:150551:1
position: 150551
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:150220-150551:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty4 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(150695..151055)
location: region:150695-151055:-1
so has part: feature:150695-151055:-1:region

S000007429
type: SGD
SIO_000068: sgd

position:150695:-1
position: 150695
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:151055:-1
position: 151055
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:150695-151055:-1:region

YNCC0009C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCC0009C
so part of: sequence
location: complement(151284..151356)
location: region:151284-151356:-1
so has part: feature:151284-151356:-1:exon
subclass of: SO_0000663

850379
type: Gene
SIO_000068: ncbigene

position:151284:-1
position: 151284
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:151356:-1
position: 151356
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:151284-151356:-1:exon

YNCC0009C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCC0009C
product: tRNA-Lys
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:8915539]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:8915539]
experiment: EXISTENCE:mutant phenotype:GO:0030533 triplet codon-amino acid adaptor activity [PMID:17560369]
experiment: EXISTENCE:mutant phenotype:GO:0032543 mitochondrial translation [PMID:17560369]
note: Lysine tRNA (tRNA-Lys), predicted by tRNAscan-SE analysis; a small portion is imported into mitochondria via interaction with mt lysyl-tRNA synthetase Msk1p and is necessary to decode AAG codons at high temperature, when base modification of mt-encoded tRNA-Lys is reduced
SIO_010081: YNCC0009C
subclass of: SO_0000673
so part of: YNCC0009C
location: complement(151284..151356)
location: region:151284-151356:-1
so has part: feature:151284-151356:-1:exon

S000006615
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:151284-151356:-1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 151521..151851
location: region:151521-151851:1
so has part: feature:151521-151851:1:region

S000006837
type: SGD
SIO_000068: sgd

position:151521:1
position: 151521
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:151851:1
position: 151851
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:151521-151851:1:region

YCR019W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MAK32
locus tag: YCR019W
so part of: sequence
location: <152837..>153928
location: region:152837-153928:1
so has part: feature:152837-153928:1:exon
subclass of: SO_0000010

850381
type: Gene
SIO_000068: ncbigene

position:152837:1
position: 152837
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:153928:1
position: 153928
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:152837-153928:1:exon

YCR019W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MAK32
locus tag: YCR019W
product: Mak32p
transcript id: NM_001178732.1
SIO_010081: YCR019W
subclass of: SO_0000673
so part of: YCR019W
location: <152837..>153928
location: region:152837-153928:1
so has part: feature:152837-153928:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:152837-153928:1:exon

YCR019W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MAK32
locus tag: YCR019W
note: Protein necessary for stability of L-A dsRNA-containing particles
codon start: 1
product: Mak32p
translation: MMNEEDSTETKSLVITNGMFIIDDIERSKYNIHYKNVPGGGGTFAILGACIISSGNVTSKGLKWIVDRGSDFPKEVIREIDSWGTDVRFRDDFSRLTTKGLNYYEGSDDLRKFKFLTPKKQINVDDWISTFGQKIIDEMHAFHLLCSGSRCLDIINDLLRVKSSKGTKPIVIWEPFPDLCDFDHQNDIKSVMQRNDVTVILSPNAEESSRLFGLSSKEPTSLEECLALAHRFDDFMDENNMCILRCGALGSISVSEKFKNGRTYDHFPAYHFKTQSKVLDPTGGGNSFLGGFAVSYALTKSLDIASICGNIAAGAIIEQFGIPRYDPIAKTWNGITFLDRLKFYLSQSGLQYNINDLYKSLTR
SIO_010081: YCR019W
subclass of: SO_0000673
so part of: YCR019W
location: 152837..153928
location: region:152837-153928:1
so has part: feature:152837-153928:1:exon

NP_009946.1
type: Protein
SIO_000068: ncbiprotein

S000000612
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:152837-153928:1:exon

YCR020C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: HIT2
gene: PET18
locus tag: YCR020C
gene synonym: HIT2
so part of: sequence
location: complement(<154012..>154659)
location: region:154012-154659:-1
so has part: feature:154012-154659:-1:exon
subclass of: SO_0000010

850382
type: Gene
SIO_000068: ncbigene

position:154012:-1
position: 154012
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:154659:-1
position: 154659
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:154012-154659:-1:exon

YCR020C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: HIT2
gene: PET18
locus tag: YCR020C
gene synonym: HIT2
product: Pet18p
transcript id: NM_001178733.1
SIO_010081: YCR020C
subclass of: SO_0000673
so part of: YCR020C
location: complement(<154012..>154659)
location: region:154012-154659:-1
so has part: feature:154012-154659:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:154012-154659:-1:exon

YCR020C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: HIT2
gene: PET18
locus tag: YCR020C
gene synonym: HIT2
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:16850348]
experiment: EXISTENCE:expression pattern:GO:0006772 thiamine metabolic process [PMID:10383756]
note: hypothetical protein; has weak similarity to proteins involved in thiamin metabolism; expression is induced in the absence of thiamin
codon start: 1
product: Pet18p
translation: MSCTTDKLIQKYDALVRKTTEHKFAKELCAGTLKDRSLYIYLSQDLQFFETSLRLICKTTSLAPTTHALITLAKKIGFFSNDENSYFHDCLELLAPSLTKEERDNFDNKAIPGVDAYINFLDELRKDASITWPSLVTSLWVAEELYWRWARDTPRAPGLHWKYQKWIDLHDGEHFQTWCEFLKAEVDKFPVEEVESIFVKVSQFEFEFFESCYNA
SIO_010081: YCR020C
subclass of: SO_0000673
so part of: YCR020C
location: complement(154012..154659)
location: region:154012-154659:-1
so has part: feature:154012-154659:-1:exon

NP_009947.1
type: Protein
SIO_000068: ncbiprotein

S000000613
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:154012-154659:-1:exon

YCR020C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LSM9
alternative label: NAA38
alternative label: SMX1
gene: MAK31
locus tag: YCR020C-A
gene synonym: LSM9; NAA38; SMX1
so part of: sequence
location: complement(<154830..>155096)
location: region:154830-155096:-1
so has part: feature:154830-155096:-1:exon
subclass of: SO_0000010

850383
type: Gene
SIO_000068: ncbigene

position:154830:-1
position: 154830
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:155096:-1
position: 155096
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:154830-155096:-1:exon

YCR020C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LSM9
alternative label: NAA38
alternative label: SMX1
gene: MAK31
locus tag: YCR020C-A
gene synonym: LSM9; NAA38; SMX1
product: Mak31p
transcript id: NM_001178734.1
SIO_010081: YCR020C-A
subclass of: SO_0000673
so part of: YCR020C-A
location: complement(<154830..>155096)
location: region:154830-155096:-1
so has part: feature:154830-155096:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:154830-155096:-1:exon

YCR020C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LSM9
alternative label: NAA38
alternative label: SMX1
gene: MAK31
locus tag: YCR020C-A
gene synonym: LSM9; NAA38; SMX1
experiment: EXISTENCE:direct assay:GO:0031417 NatC complex [PMID:10504710]
experiment: EXISTENCE:mutant phenotype:GO:0004596 peptide alpha-N-acetyltransferase activity [PMID:11274203]
experiment: EXISTENCE:mutant phenotype:GO:0006474 N-terminal protein amino acid acetylation [PMID:11274203]
note: Non-catalytic subunit of N-terminal acetyltransferase of the NatC type; required for replication of dsRNA virus; member of the Sm protein family
codon start: 1
product: Mak31p
translation: MDILKLSDFIGNTLIVSLTEDRILVGSLVAVDAQMNLLLDHVEERMGSSSRMMGLVSVPRRSVKTIMIDKPVLQELTANKVELMANIV
SIO_010081: YCR020C-A
subclass of: SO_0000673
so part of: YCR020C-A
location: complement(154830..155096)
location: region:154830-155096:-1
so has part: feature:154830-155096:-1:exon

NP_009948.1
type: Protein
SIO_000068: ncbiprotein

S000000614
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:154830-155096:-1:exon

YCR020W-B
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HTL1
locus tag: YCR020W-B
so part of: sequence
location: <155320..>155556
location: region:155320-155556:1
so has part: feature:155320-155556:1:exon
subclass of: SO_0000010

850384
type: Gene
SIO_000068: ncbigene

position:155320:1
position: 155320
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:155556:1
position: 155556
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:155320-155556:1:exon

YCR020W-B
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HTL1
locus tag: YCR020W-B
product: Htl1p
transcript id: NM_001184313.1
SIO_010081: YCR020W-B
subclass of: SO_0000673
so part of: YCR020W-B
location: <155320..>155556
location: region:155320-155556:1
so has part: feature:155320-155556:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:155320-155556:1:exon

YCR020W-B
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: HTL1
locus tag: YCR020W-B
experiment: EXISTENCE:curator inference:GO:0003682 chromatin binding [PMID:12417720]
experiment: EXISTENCE:curator inference:GO:0006338 chromatin remodeling [PMID:12417720]
experiment: EXISTENCE:direct assay:GO:0006337 nucleosome disassembly [PMID:16492771]
experiment: EXISTENCE:direct assay:GO:0006368 transcription elongation by RNA polymerase II promoter [PMID:17081996]
experiment: EXISTENCE:direct assay:GO:0016586 RSC-type complex [PMID:12417720]
note: Component of the RSC chromatin remodeling complex; RSC functions in transcriptional regulation and elongation, chromosome stability, and establishing sister chromatid cohesion; involved in telomere maintenance
codon start: 1
product: Htl1p
translation: MSQNNTISSMNPERAYNNVTLKNLTAFQLLSQRENICELLNLVESTERHNSIINPERQRMSLEEMKKMLDALKNERKK
SIO_010081: YCR020W-B
subclass of: SO_0000673
so part of: YCR020W-B
location: 155320..155556
location: region:155320-155556:1
so has part: feature:155320-155556:1:exon

NP_009949.1
type: Protein
SIO_000068: ncbiprotein

S000006439
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:155320-155556:1:exon

YCR021C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YRO1
gene: HSP30
locus tag: YCR021C
gene synonym: YRO1
so part of: sequence
location: complement(<156109..>157107)
location: region:156109-157107:-1
so has part: feature:156109-157107:-1:exon
subclass of: SO_0000010

850385
type: Gene
SIO_000068: ncbigene

position:156109:-1
position: 156109
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:157107:-1
position: 157107
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:156109-157107:-1:exon

YCR021C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YRO1
gene: HSP30
locus tag: YCR021C
gene synonym: YRO1
product: Hsp30p
transcript id: NM_001178735.1
SIO_010081: YCR021C
subclass of: SO_0000673
so part of: YCR021C
location: complement(<156109..>157107)
location: region:156109-157107:-1
so has part: feature:156109-157107:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:156109-157107:-1:exon

YCR021C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YRO1
gene: HSP30
locus tag: YCR021C
gene synonym: YRO1
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:1535043|PMID:16622836]
experiment: EXISTENCE:mutant phenotype:GO:0032780 negative regulation of ATP-dependent activity [PMID:9250391]
note: Negative regulator of the H(+)-ATPase Pma1p; stress-responsive protein; hydrophobic plasma membrane localized; induced by heat shock, ethanol treatment, weak organic acid, glucose limitation, and entry into stationary phase
codon start: 1
product: Hsp30p
translation: MNDTLSSFLNRNEALGLNPPHGLDMHITKRGSDWLWAVFAVFGFILLCYVVMFFIAENKGSRLTRYALAPAFLITFFEFFAFFTYASDLGWTGVQAEFNHVKVSKSITGEVPGIRQIFYSKYIAWFLSWPCLLFLIELAASTTGENDDISALDMVHSLLIQIVGTLFWVVSLLVGSLIKSTYKWGYYTIGAVAMLVTQGVICQRQFFNLKTRGFNALMLCTCMVIVWLYFICWGLSDGGNRIQPDGEAIFYGVLDLCVFAIYPCYLLIAVSRDGKLPRLSLTGGFSHHHATDDVEDAAPETKEAVPESPRASGETAIHEPEPEAEQAVEDTA
SIO_010081: YCR021C
subclass of: SO_0000673
so part of: YCR021C
location: complement(156109..157107)
location: region:156109-157107:-1
so has part: feature:156109-157107:-1:exon

NP_009950.1
type: Protein
SIO_000068: ncbiprotein

S000000615
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:156109-157107:-1:exon

YCR022C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCR022C
so part of: sequence
location: complement(<157421..>157765)
location: region:157421-157765:-1
so has part: feature:157421-157765:-1:exon
subclass of: SO_0000010

850386
type: Gene
SIO_000068: ncbigene

position:157421:-1
position: 157421
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:157765:-1
position: 157765
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:157421-157765:-1:exon

YCR022C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCR022C
product: uncharacterized protein
transcript id: NM_001348895.1
SIO_010081: YCR022C
subclass of: SO_0000673
so part of: YCR022C
location: complement(<157421..>157765)
location: region:157421-157765:-1
so has part: feature:157421-157765:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:157421-157765:-1:exon

YCR022C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YCR022C
note: hypothetical protein; conserved among S. cerevisiae strains; YCR022C is not an essential gene
codon start: 1
product: uncharacterized protein
translation: MENRCSNPCYIQSDPSDLLSLRLPARFCWPFSRSSRIFQGSSRRRILSEGKNASKACFVRIFGMAKVSKAISRSRSRLLFRSLPPHPACLFEYQISSSSLFHHPFLLWQGQVFF
SIO_010081: YCR022C
subclass of: SO_0000673
so part of: YCR022C
location: complement(157421..157765)
location: region:157421-157765:-1
so has part: feature:157421-157765:-1:exon

NP_001335750.1
type: Protein
SIO_000068: ncbiprotein

S000000616
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:157421-157765:-1:exon

YCR023C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCR023C
so part of: sequence
location: complement(<158538..>160373)
location: region:158538-160373:-1
so has part: feature:158538-160373:-1:exon
subclass of: SO_0000010

850387
type: Gene
SIO_000068: ncbigene

position:158538:-1
position: 158538
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:160373:-1
position: 160373
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:158538-160373:-1:exon

YCR023C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCR023C
product: uncharacterized protein
transcript id: NM_001178737.1
SIO_010081: YCR023C
subclass of: SO_0000673
so part of: YCR023C
location: complement(<158538..>160373)
location: region:158538-160373:-1
so has part: feature:158538-160373:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:158538-160373:-1:exon

YCR023C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YCR023C
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:12562762]
note: Vacuolar membrane hypothetical protein; targeted to vacuole via AP-3 pathway; member of multidrug resistance family; not an essential gene
codon start: 1
product: uncharacterized protein
translation: MARQKLTFKEQMDGFPWVQLVVVSLVRFSEPIAFSSLFPYVYFMVRDFNIAPNDAQVSKYSGYLSSSFALCQVISAYHWGRFSEKHGRKITLTCGLIGTSVSLLILGFSRNFYQALVARSLMGLLNGNVGVIRTIIGEIATERKHQALAFSTMPLLFQFGAVVGPMIGGFLVFRDGTMNEVPLWFPHFAKRIIRSYPYALPNVVVCMFLMFGLTNATLFLEETHPAFKDRRDYGLEVGDFIKKNIFGIQPKRRPWQKRIQDDSENIHHRNENVNSIRGQDSEEDENSPLVNTTNDDDTESIQSIDPILTRRQSVGLIRTYSLHEPTDAVHANIDTAPDGCKESSIFHHVFHTKVFYPISVNFIMALHLIVYNEFLPVFLAYDLAVDPENPKKLASKFPWKISGGIGYEPEQTGTLLSTTGIFGCFVVIFIFPIVDRNFDCLTIFRTLVKLYPIMYVMVPYVVFLQNERIPSWYTVVYLYIITGIKTFCGALTSPQIMLLIHNSSPLSCRSVINGATISISASARFIGPLVWGYIMSWSQQNDVAWVSWWSLSLFCMVALYQSYKIAPIDDNENELHGQGSEDAYNSQSQSSDLRMAHRSSLSSLSNQRCTT
SIO_010081: YCR023C
subclass of: SO_0000673
so part of: YCR023C
location: complement(158538..160373)
location: region:158538-160373:-1
so has part: feature:158538-160373:-1:exon

NP_009952.2
type: Protein
SIO_000068: ncbiprotein

S000000617
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:158538-160373:-1:exon

YCR024C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SLM5
locus tag: YCR024C
so part of: sequence
location: complement(<160744..>162222)
location: region:160744-162222:-1
so has part: feature:160744-162222:-1:exon
subclass of: SO_0000010

850388
type: Gene
SIO_000068: ncbigene

position:160744:-1
position: 160744
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:162222:-1
position: 162222
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:160744-162222:-1:exon

YCR024C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SLM5
locus tag: YCR024C
product: asparagine--tRNA ligase SLM5
transcript id: NM_001178738.1
SIO_010081: YCR024C
subclass of: SO_0000673
so part of: YCR024C
location: complement(<160744..>162222)
location: region:160744-162222:-1
so has part: feature:160744-162222:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:160744-162222:-1:exon

YCR024C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SLM5
locus tag: YCR024C
EC number: 6.1.1.22
experiment: EXISTENCE:direct assay:GO:0004816 asparagine-tRNA ligase activity [PMID:9030748]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0006421 asparaginyl-tRNA aminoacylation [PMID:9030748]
experiment: EXISTENCE:mutant phenotype:GO:0005739 mitochondrion [PMID:9030748]
experiment: EXISTENCE:mutant phenotype:GO:0070145 mitochondrial asparaginyl-tRNA aminoacylation [PMID:9030748]
note: Mitochondrial asparaginyl-tRNA synthetase
codon start: 1
product: asparagine--tRNA ligase SLM5
translation: MFHAFTFLKGGRFYSSLTVKSLYEQVHHTSHDPISINGWIKSIRLLKRIAFLDLQDGTSVNPLRIVIPLTNTDEVQFLKILKTGQTLSISNATWQSTPNRKQPFELQIKNPVKSIKLVGPVSENYPLQKKYQTLRYLRSLPTLKYRTAYLSAILRLRSFVEFQFMLYFQKNHFTKVSPPILTSNDCEGAGELFQVSTNTSPTASSYFGKPTYLTVSTQLHLEILALSLSRCWTLSPCFRAEKSDTPRHLSEFWMLEVEMCFVNSVNELTSFVETTIKHIIKACIDNQQELLPKQFISSQENNASSELSINQETQQIKTRWEDLINEKWHNITYTNAIEILKKRHNEVSHFKYEPKWGQPLQTEHEKFLAGEYFKSPVFVTDYPRLCKPFYMKQNSTPDDTVGCFDLLVPGMGEIIGGSLREDDYDKLCREMKARGMNRSGELDWYVSLRKEGSAPHGGFGLGFERFISYLYGNHNIKDAIPFYRTSAESIDF
SIO_010081: YCR024C
subclass of: SO_0000673
so part of: YCR024C
location: complement(160744..162222)
location: region:160744-162222:-1
so has part: feature:160744-162222:-1:exon

NP_009953.1
type: Protein
SIO_000068: ncbiprotein

S000000618
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:160744-162222:-1:exon

YCR024C-B
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCR024C-B
so part of: sequence
location: complement(<162599..>162865)
location: region:162599-162865:-1
so has part: feature:162599-162865:-1:exon
subclass of: SO_0000010

1466398
type: Gene
SIO_000068: ncbigene

position:162599:-1
position: 162599
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:162865:-1
position: 162865
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:162599-162865:-1:exon

YCR024C-B
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCR024C-B
product: uncharacterized protein
transcript id: NM_001184645.1
SIO_010081: YCR024C-B
subclass of: SO_0000673
so part of: YCR024C-B
location: complement(<162599..>162865)
location: region:162599-162865:-1
so has part: feature:162599-162865:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:162599-162865:-1:exon

YCR024C-B
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YCR024C-B
note: hypothetical protein; identified by expression profiling and mass spectrometry
codon start: 1
product: uncharacterized protein
translation: MCVCAIPFFEFFLPFIPHYAFLLFVSSVRFTVNERCYYLVCVLKLNCAFFFMVMIFELKRVCVSYLDRSRKIQIVSFFPFITIIFFHS
SIO_010081: YCR024C-B
subclass of: SO_0000673
so part of: YCR024C-B
location: complement(162599..162865)
location: region:162599-162865:-1
so has part: feature:162599-162865:-1:exon

NP_878057.1
type: Protein
SIO_000068: ncbiprotein

S000028818
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:162599-162865:-1:exon

YCR024C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PMP1
locus tag: YCR024C-A
so part of: sequence
location: complement(<162945..>163067)
location: region:162945-163067:-1
so has part: feature:162945-163067:-1:exon
subclass of: SO_0000010

850389
type: Gene
SIO_000068: ncbigene

position:162945:-1
position: 162945
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:163067:-1
position: 163067
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:162945-163067:-1:exon

YCR024C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PMP1
locus tag: YCR024C-A
product: proteolipid ATPase
transcript id: NM_001178739.1
SIO_010081: YCR024C-A
subclass of: SO_0000673
so part of: YCR024C-A
location: complement(<162945..>163067)
location: region:162945-163067:-1
so has part: feature:162945-163067:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:162945-163067:-1:exon

YCR024C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PMP1
locus tag: YCR024C-A
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:1532582]
experiment: EXISTENCE:direct assay:GO:0016020 membrane [PMID:1532582]
experiment: EXISTENCE:genetic interaction:GO:0030234 enzyme regulator activity [PMID:8063750]
experiment: EXISTENCE:genetic interaction:GO:0032781 positive regulation of ATP-dependent activity [PMID:8063750]
note: Regulatory subunit for the plasma membrane H(+)-ATPase Pma1p; small single-membrane span proteolipid; forms unique helix and positively charged cytoplasmic domain that is able to specifically segregate phosphatidylserines; PMP1 has a paralog, PMP2, that arose from the whole genome duplication
codon start: 1
product: proteolipid ATPase
translation: MTLPGGVILVFILVGLACIAIIATIIYRKWQARQRGLQRF
SIO_010081: YCR024C-A
subclass of: SO_0000673
so part of: YCR024C-A
location: complement(162945..163067)
location: region:162945-163067:-1
so has part: feature:162945-163067:-1:exon

NP_058137.1
type: Protein
SIO_000068: ncbiprotein

S000000619
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:162945-163067:-1:exon

YCR025C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCR025C
so part of: sequence
location: complement(<163446..>163856)
location: region:163446-163856:-1
so has part: feature:163446-163856:-1:exon
subclass of: SO_0000010

850390
type: Gene
SIO_000068: ncbigene

position:163446:-1
position: 163446
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:163856:-1
position: 163856
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:163446-163856:-1:exon

YCR025C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCR025C
product: uncharacterized protein
transcript id: NM_001348896.1
SIO_010081: YCR025C
subclass of: SO_0000673
so part of: YCR025C
location: complement(<163446..>163856)
location: region:163446-163856:-1
so has part: feature:163446-163856:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:163446-163856:-1:exon

YCR025C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YCR025C
note: hypothetical protein; conserved across S. cerevisiae strains; YCR025C is not an essential gene
codon start: 1
product: uncharacterized protein
translation: MSSFGHRAFFSCCPLLEGETLHSIKLRKEATYQTQSGWPVRWPIRYPRALPLESHVHPYHMIVKLPHPRTQPRLFLWLSLHWTGIPFLGKPGIGRNRVKSKQFSHFQQSKIKTTMRKKTTNRKQKAERCQYRLVTA
SIO_010081: YCR025C
subclass of: SO_0000673
so part of: YCR025C
location: complement(163446..163856)
location: region:163446-163856:-1
so has part: feature:163446-163856:-1:exon

NP_001335751.1
type: Protein
SIO_000068: ncbiprotein

S000000620
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:163446-163856:-1:exon

YCR026C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: NPP1
locus tag: YCR026C
so part of: sequence
location: complement(<164111..>166339)
location: region:164111-166339:-1
so has part: feature:164111-166339:-1:exon
subclass of: SO_0000010

850391
type: Gene
SIO_000068: ncbigene

position:164111:-1
position: 164111
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:166339:-1
position: 166339
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:164111-166339:-1:exon

YCR026C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: NPP1
locus tag: YCR026C
product: nucleotide diphosphatase/phosphodiesterase NPP1
transcript id: NM_001178741.1
SIO_010081: YCR026C
subclass of: SO_0000673
so part of: YCR026C
location: complement(<164111..>166339)
location: region:164111-166339:-1
so has part: feature:164111-166339:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:164111-166339:-1:exon

YCR026C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: NPP1
locus tag: YCR026C
EC number: 3.1.4.1
EC number: 3.6.1.9
experiment: EXISTENCE:direct assay:GO:0047429 nucleoside triphosphate diphosphatase activity [PMID:16278456]
experiment: EXISTENCE:genetic interaction:GO:0017111 ribonucleoside triphosphate phosphatase activity [PMID:16278456]
experiment: EXISTENCE:genetic interaction:GO:0047429 nucleoside triphosphate diphosphatase activity [PMID:16278456]
experiment: EXISTENCE:mutant phenotype:GO:0009141 nucleoside triphosphate metabolic process [PMID:16278456]
experiment: EXISTENCE:mutant phenotype:GO:0016036 cellular response to phosphate starvation [PMID:16278456]
experiment: EXISTENCE:mutant phenotype:GO:0017111 ribonucleoside triphosphate phosphatase activity [PMID:16278456]
experiment: EXISTENCE:mutant phenotype:GO:0047429 nucleoside triphosphate diphosphatase activity [PMID:16278456]
note: Nucleotide pyrophosphatase/phosphodiesterase; mediates extracellular nucleotide phosphate hydrolysis along with Npp2p and Pho5p; activity and expression enhanced during conditions of phosphate starvation; involved in spore wall assembly; NPP1 has a paralog, NPP2, that arose from the whole genome duplication, and an npp1 npp2 double mutant exhibits reduced dityrosine fluorescence relative to the single mutants
codon start: 1
product: nucleotide diphosphatase/phosphodiesterase NPP1
translation: MELQNDLESLDNELNDFSEDPFRDDFITDEDAVRSGWRSAWTRMKYWFYKNRLKWTNNPIVIGDAKDSRDGSNFRRGIPLYELDANGQPIDTELVDENELSFGTGFHSKVPFKIIFRTLFGSLVFAIFLILMINIAKPHHSTRVLSHFGSPEFDPYVKYFNGTHEFFPLTIVISLDGFHPSLISKRNTPFLHDLYELKYDGGMNITSTPFMVPSFPTETFPNHWTLVTGQYPIHHGIVSNVFWDPDLNEEFHPGVLDPRIWNNNDTEPIWQTVQSAFDGDIPFKAATHMWPGSDVNYTKYNEEKLQPEHKNPIARERTPFYFDEFNAKEPLSQKLSKIIEYVDMSTLNERPQLILGYVPNVDAFGHKHGYPSESEYYYEDFTETLGEVDTFLKQLVESLQERNLTSFTNLVIVSDHGMSDIVVPSNVIIWEDLLDEKLRKDYVSHAYLEGPMMAISLKDSGNINEVYHNLKTSIDEDKYTVYVNGNFPKEWNFNDGKNHHMASIWIVPEPGYAVMKKEQLKKVAKGDHKDKNEDNVFTIGSHGYDNNAIDMRSVFIGMGPYFPQGYIEPFQNTEIYNLLCDICGVAEKDRNSNDGTGMLMNQLREPQSSEEVEIEDDFDYLVSKFGEFSTYNIIWGGYPEETEQDNVDNDNDDNDDGNTDEIAAMPSSSLTIKLEMTTSIPSATETLLGETSPSSRSSSSSSIQASATASTVGDWLQDIINDAKDLIDDIIDSIDDLVDSDT
SIO_010081: YCR026C
subclass of: SO_0000673
so part of: YCR026C
location: complement(164111..166339)
location: region:164111-166339:-1
so has part: feature:164111-166339:-1:exon

NP_009955.2
type: Protein
SIO_000068: ncbiprotein

S000000621
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:164111-166339:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS310; Compound autonomously replicating sequence on Chromosome III
so part of: sequence
location: 166503..167348
location: region:166503-167348:1
so has part: feature:166503-167348:1:region

S000028487
type: SGD
SIO_000068: sgd

position:166503:1
position: 166503
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:167348:1
position: 167348
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:166503-167348:1:region

YCR027C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RSG1
gene: RHB1
locus tag: YCR027C
gene synonym: RSG1
so part of: sequence
location: complement(<167370..>167999)
location: region:167370-167999:-1
so has part: feature:167370-167999:-1:exon
subclass of: SO_0000010

850392
type: Gene
SIO_000068: ncbigene

position:167370:-1
position: 167370
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:167999:-1
position: 167999
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:167370-167999:-1:exon

YCR027C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RSG1
gene: RHB1
locus tag: YCR027C
gene synonym: RSG1
product: putative GTPase RHB1
transcript id: NM_001178742.1
SIO_010081: YCR027C
subclass of: SO_0000673
so part of: YCR027C
location: complement(<167370..>167999)
location: region:167370-167999:-1
so has part: feature:167370-167999:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:167370-167999:-1:exon

YCR027C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RSG1
gene: RHB1
locus tag: YCR027C
gene synonym: RSG1
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0042147 retrograde transport, endosome to Golgi [PMID:17101785]
note: Putative Rheb-related GTPase; involved in regulating canavanine resistance and arginine uptake; member of the Ras superfamily of G-proteins
codon start: 1
product: putative GTPase RHB1
translation: MEYATMSSSNSTHNFQRKIALIGARNVGKTTLTVRFVESRFVESYYPTIENEFTRIIPYKSHDCTLEILDTAGQDEVSLLNIKSLTGVRGIILCYSIINRASFDLIPILWDKLVDQLGKDNLPVILVGTKADLGRSTKGVKRCVTKAEGEKLASTIGSQDKRNQAAFIECSAELDYNVEETFMLLLKQMERVEGTLGLDAENNNKCSIM
SIO_010081: YCR027C
subclass of: SO_0000673
so part of: YCR027C
location: complement(167370..167999)
location: region:167370-167999:-1
so has part: feature:167370-167999:-1:exon

NP_009956.2
type: Protein
SIO_000068: ncbiprotein

S000000622
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:167370-167999:-1:exon

YNCC0010C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCC0010C
so part of: sequence
location: complement(168301..168372)
location: region:168301-168372:-1
so has part: feature:168301-168372:-1:exon
subclass of: SO_0000663

850393
type: Gene
SIO_000068: ncbigene

position:168301:-1
position: 168301
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:168372:-1
position: 168372
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:168301-168372:-1:exon

YNCC0010C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCC0010C
product: tRNA-Gln
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:15706032]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:15706032]
note: Glutamine tRNA (tRNA-Gln), predicted by tRNAscan-SE analysis; thiolation of uridine at wobble position (34) requires Ncs6p
SIO_010081: YNCC0010C
subclass of: SO_0000673
so part of: YNCC0010C
location: complement(168301..168372)
location: region:168301-168372:-1
so has part: feature:168301-168372:-1:exon

S000006692
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:168301-168372:-1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 169573..169888
location: region:169573-169888:1
so has part: feature:169573-169888:1:region

S000006838
type: SGD
SIO_000068: sgd

position:169573:1
position: 169573
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:169888:1
position: 169888
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:169573-169888:1:region

YCR028C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FEN2
locus tag: YCR028C
so part of: sequence
location: complement(<170886..>172424)
location: region:170886-172424:-1
so has part: feature:170886-172424:-1:exon
subclass of: SO_0000010

850394
type: Gene
SIO_000068: ncbigene

position:170886:-1
position: 170886
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:172424:-1
position: 172424
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:170886-172424:-1:exon

YCR028C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FEN2
locus tag: YCR028C
product: Fen2p
transcript id: NM_001178743.1
SIO_010081: YCR028C
subclass of: SO_0000673
so part of: YCR028C
location: complement(<170886..>172424)
location: region:170886-172424:-1
so has part: feature:170886-172424:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:170886-172424:-1:exon

YCR028C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FEN2
locus tag: YCR028C
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0005886 plasma membrane [PMID:10373490]
experiment: EXISTENCE:mutant phenotype:GO:0006897 endocytosis [PMID:15020461]
experiment: EXISTENCE:mutant phenotype:GO:0015233 pantothenate transmembrane transporter activity [PMID:10373490]
experiment: EXISTENCE:mutant phenotype:GO:0015887 pantothenate transmembrane transport [PMID:10373490]
note: Plasma membrane H+-pantothenate symporter; confers sensitivity to the antifungal agent fenpropimorph; relocalizes from vacuole to cytoplasm upon DNA replication stress
codon start: 1
product: Fen2p
translation: MMKESKSITQHEVERESVSSKRAIKKRLLLFKIDLFVLSFVCLQYWINYVDRVGFTNAYISGMKEDLKMVGNDLTVSNTVFMIGYIVGMVPNNLMLLCVPPRIWLSFCTFAWGLLTLGMYKVTSFKHICAIRFFQALFESCTFSGTHFVLGSWYKEDELPIRSAIFTGSGLVGSMFSGFMQTSIFTHLNGRNGLAGWRWLFIIDFCITLPIAIYGFIFFPGLPDQTSAVSKFSMTRYIFNEQELHYARRRLPARDESTRLDWSTIPRVLKRWHWWMFSLVWVLGGENLGFASNSTFALWLQNQKYTLAQRNNYPSGIFAVGIVSTLCSAVYMSKIPRARHWHVSVFISLVMVIVAVLIRADPLNPKVVFSAQYLGGVAYAGQAVFFSWANIICHADLQERAIVLASMNMFSGAVNAWWSILFFASDMVPKFERGCYALLATAISSGIVSVVIRSLQIKENLSKKQVPYIDANDMPGEDDDDDNQDNENDGDDESMEVELHNEEMAEISNPFR
SIO_010081: YCR028C
subclass of: SO_0000673
so part of: YCR028C
location: complement(170886..172424)
location: region:170886-172424:-1
so has part: feature:170886-172424:-1:exon

NP_009957.1
type: Protein
SIO_000068: ncbiprotein

S000000623
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:170886-172424:-1:exon

YCR028C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RIM1
locus tag: YCR028C-A
so part of: sequence
location: complement(<172950..>173440)
location: region:172950-173440:-1
so has part: feature:172950-173440:-1:exon
subclass of: SO_0000010

850395
type: Gene
SIO_000068: ncbigene

position:172950:-1
position: 172950
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:173440:-1
position: 173440
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:172950-173440:-1:exon

YCR028C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RIM1
locus tag: YCR028C-A
product: Rim1p
transcript id: NM_001184315.1
SIO_010081: YCR028C-A
subclass of: SO_0000673
so part of: YCR028C-A
location: complement(join(<172950..173115,173199..>173440))
location: region:172950-173440:-1
so has part: feature:173199-173440:-1:exon
so has part: feature:172950-173115:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:173199-173440:-1:exon

position:173199:-1
position: 173199
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:172950-173115:-1:exon

position:173115:-1
position: 173115
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YCR028C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RIM1
locus tag: YCR028C-A
experiment: EXISTENCE:direct assay:GO:0003697 single-stranded DNA binding [PMID:1324172]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:1324172|PMID:24769239|PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0042645 mitochondrial nucleoid [PMID:10869431]
experiment: EXISTENCE:direct assay:GO:0090297 positive regulation of mitochondrial DNA replication [PMID:26184436]
experiment: EXISTENCE:mutant phenotype:GO:0000002 mitochondrial genome maintenance [PMID:1324172]
note: ssDNA-binding protein essential for mitochondrial genome maintenance; involved in mitochondrial DNA replication; stimulates utilization by Mip1p DNA polymerase of RNA primers synthesized by Rpo41p
codon start: 1
product: Rim1p
translation: MFLRTQARFFHATTKKMDFSKMSIVGRIGSEFTEHTSANNNRYLKYSIASQPRRDGQTNWYNITVFNEPQINFLTEYVRKGALVYVEADAANYVFERDDGSKGTTLSLVQKDINLLKNGKKLEDAEGQENAASSE
SIO_010081: YCR028C-A
subclass of: SO_0000673
so part of: YCR028C-A
location: complement(join(172950..173115,173199..173440))
location: region:172950-173440:-1
so has part: feature:173199-173440:-1:exon
so has part: feature:172950-173115:-1:exon

NP_009958.2
type: Protein
SIO_000068: ncbiprotein

S000007222
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:173199-173440:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:172950-173115:-1:exon

YCR030C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YCR029C-A
gene: SYP1
locus tag: YCR030C
gene synonym: YCR029C-A
so part of: sequence
location: complement(<173826..>176438)
location: region:173826-176438:-1
so has part: feature:173826-176438:-1:exon
subclass of: SO_0000010

850396
type: Gene
SIO_000068: ncbigene

position:173826:-1
position: 173826
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:176438:-1
position: 176438
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:173826-176438:-1:exon

YCR030C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YCR029C-A
gene: SYP1
locus tag: YCR030C
gene synonym: YCR029C-A
product: Syp1p
transcript id: NM_001178744.1
SIO_010081: YCR030C
subclass of: SO_0000673
so part of: YCR030C
location: complement(<173826..>176438)
location: region:173826-176438:-1
so has part: feature:173826-176438:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:173826-176438:-1:exon

YCR030C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YCR029C-A
gene: SYP1
locus tag: YCR030C
gene synonym: YCR029C-A
experiment: EXISTENCE:direct assay:GO:0000144 cellular bud neck septin ring [PMID:26179915]
experiment: EXISTENCE:direct assay:GO:0001400 mating projection base [PMID:11014808]
experiment: EXISTENCE:direct assay:GO:0004857 enzyme inhibitor activity [PMID:19962315]
experiment: EXISTENCE:direct assay:GO:0005628 prospore membrane [PMID:24390141]
experiment: EXISTENCE:direct assay:GO:0005934 cellular bud tip [PMID:11014808]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:11014808]
experiment: EXISTENCE:direct assay:GO:0043086 negative regulation of catalytic activity [PMID:19962315]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:19053807]
experiment: EXISTENCE:direct assay:GO:0061645 endocytic patch [PMID:19962315]
experiment: EXISTENCE:genetic interaction:GO:0032185 septin cytoskeleton organization [PMID:18791237]
experiment: EXISTENCE:mutant phenotype:GO:0000147 actin cortical patch assembly [PMID:19776351]
experiment: EXISTENCE:mutant phenotype:GO:0032185 septin cytoskeleton organization [PMID:18791237]
experiment: EXISTENCE:physical interaction:GO:0032185 septin cytoskeleton organization [PMID:18791237]
note: Negative regulator of WASP-Arp23 complex; involved in endocytic site formation; directly inhibits Las17p stimulation of Arp23 complex-mediated actin assembly in vitro; may regulate assembly and disassembly of the septin ring; colocalizes and interacts with septin subunits; potential role in actin cytoskeletal organization
codon start: 1
product: Syp1p
translation: MTEQRTKYADSILTTKSPYEATETIRIRLSQVKLLNKDFYLLFKELANLKRNYAQQLRKIIAENEDITKILNAQMIESNVLTPQEMSAFRFNSLGELRNVWDTVIEELKSDLKSSTEYYNTLDQQVVRELKESVENNTSWRESKDLHSKLSKNAASIEHYSKNNENSSHLEEARRQWDQQSPYLFELFETIDYNRLDTLKNCMLRFQTSFSDYLLNTTKECETVMTKFLAFEPQSEIDRFAKDASQYNFQLSSSSKEVVPNNASPASATGARPVSVSNGAANTEREKKSPQKDKRKSAFGNIGHRLASASSSLTHNDLMNNEFSDSTNNSSLKSKKSSHTLRSKVGSIFGRNKTKNKRQQQSSSNSHIQASITETPNNSSTRVSSTATSSIYQKQRRPTYSSSKSNNWTPGEASDTPPLPPHATPKNVDAPVTADTPPAQTFTPSEVPPSTPQQSSPPTAKEPDSSNLPKTVPISISQPPLQPQSKTKPLPVEPASPSISLPTATVDNQPSGQVDSRPLHIRAPALPPSRKQNFIHNRDSQLYDSLPNHGSGATPTSSSLSSIPQERPVSTLSSQITGELRELNPQATGSSTSLVGQSLFQHSSLDTSQFGLNASIAEVLNASFKDGMLQNSQLIGEIALNYLPNSVMNSPLPIGINLRINNGAKFEKVILNQAFIERVAPEEFKVNPSFIDSRTLGAIKYSIKEPIAPIVIHPVWRFESHQASVVLTVKMSPSLPDEISQIVIEDLVVFVNIDGANATSALSKPQGSFSKEKKRITWRFKEPVVLTRNGEGQRLIARFITDGLAHESAKGVITKFTISETDNVALPHSGAGSGITLTCQELDENNPFGGEWLDVNTKRTLTTGNYHGLA
SIO_010081: YCR030C
subclass of: SO_0000673
so part of: YCR030C
location: complement(173826..176438)
location: region:173826-176438:-1
so has part: feature:173826-176438:-1:exon

NP_009959.2
type: Protein
SIO_000068: ncbiprotein

S000000626
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:173826-176438:-1:exon

YNCC0011W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SNR65
locus tag: YNCC0011W
so part of: sequence
location: 177183..177282
location: region:177183-177282:1
so has part: feature:177183-177282:1:exon
subclass of: SO_0000578

9164872
type: Gene
SIO_000068: ncbigene

position:177183:1
position: 177183
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:177282:1
position: 177282
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:177183-177282:1:exon

YNCC0011W
type: Non Coding RNA
subclass of: SO_0000655
RO_0002162: 559292
nc RNA class: snoRNA
gene: SNR65
locus tag: YNCC0011W
product: SNR65
experiment: EXISTENCE:curator inference:GO:0005730 nucleolus [PMID:10024243]
experiment: EXISTENCE:curator inference:GO:0031428 box C/D RNP complex [PMID:10024243]
experiment: EXISTENCE:mutant phenotype:GO:0030562 rRNA 2'-O-ribose methylation guide activity [PMID:10024243]
experiment: EXISTENCE:mutant phenotype:GO:0031167 rRNA methylation [PMID:10024243]
note: C/D box small nucleolar RNA (snoRNA); guides 2'-O-methylation of large subunit (LSU) rRNA at position U2347
transcript id: NR_132157.1
SIO_010081: YNCC0011W
subclass of: SO_0000673
so part of: YNCC0011W
location: 177183..177282
location: region:177183-177282:1
so has part: feature:177183-177282:1:exon

S000006456
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:177183-177282:1:exon

YCR031C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CRY1
alternative label: RPL59
gene: RPS14A
locus tag: YCR031C
gene synonym: CRY1; RPL59
so part of: sequence
location: complement(<177500..>178220)
location: region:177500-178220:-1
so has part: feature:177500-178220:-1:exon
subclass of: SO_0000010

850397
type: Gene
SIO_000068: ncbigene

position:177500:-1
position: 177500
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:178220:-1
position: 178220
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:177500-178220:-1:exon

YCR031C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CRY1
alternative label: RPL59
gene: RPS14A
locus tag: YCR031C
gene synonym: CRY1; RPL59
product: ribosomal 40S subunit protein S14A
transcript id: NM_001178745.1
SIO_010081: YCR031C
subclass of: SO_0000673
so part of: YCR031C
location: complement(join(<177500..177906,178214..>178220))
location: region:177500-178220:-1
so has part: feature:178214-178220:-1:exon
so has part: feature:177500-177906:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:178214-178220:-1:exon

position:178214:-1
position: 178214
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:177500-177906:-1:exon

position:177906:-1
position: 177906
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YCR031C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CRY1
alternative label: RPL59
gene: RPS14A
locus tag: YCR031C
gene synonym: CRY1; RPL59
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:9858605]
experiment: EXISTENCE:direct assay:GO:0030686 90S preribosome [PMID:12150911]
experiment: EXISTENCE:direct assay:GO:0032040 small-subunit processome [PMID:15590835]
experiment: EXISTENCE:genetic interaction:GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:16246728]
experiment: EXISTENCE:mutant phenotype:GO:0000028 ribosomal small subunit assembly [PMID:2277060|PMID:8293976]
experiment: EXISTENCE:mutant phenotype:GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:15125836]
note: Protein component of the small (40S) ribosomal subunit; required for ribosome assembly and 20S pre-rRNA processing; mutations confer cryptopleurine resistance; homologous to mammalian ribosomal protein S14 and bacterial S11; RPS14A has a paralog, RPS14B, that arose from the whole genome duplication
codon start: 1
product: ribosomal 40S subunit protein S14A
translation: MSNVVQARDNSQVFGVARIYASFNDTFVHVTDLSGKETIARVTGGMKVKADRDESSPYAAMLAAQDVAAKCKEVGITAVHVKIRATGGTRTKTPGPGGQAALRALARSGLRIGRIEDVTPVPSDSTRKKGGRRGRRL
SIO_010081: YCR031C
subclass of: SO_0000673
so part of: YCR031C
location: complement(join(177500..177906,178214..178220))
location: region:177500-178220:-1
so has part: feature:178214-178220:-1:exon
so has part: feature:177500-177906:-1:exon

NP_009960.2
type: Protein
SIO_000068: ncbiprotein

S000000627
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:178214-178220:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:177500-177906:-1:exon

YNCC0012C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SNR189
locus tag: YNCC0012C
so part of: sequence
location: complement(178610..178798)
location: region:178610-178798:-1
so has part: feature:178610-178798:-1:exon
subclass of: SO_0000578

9164873
type: Gene
SIO_000068: ncbigene

position:178610:-1
position: 178610
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:178798:-1
position: 178798
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:178610-178798:-1:exon

YNCC0012C
type: Non Coding RNA
subclass of: SO_0000655
RO_0002162: 559292
nc RNA class: snoRNA
gene: SNR189
locus tag: YNCC0012C
product: SNR189
experiment: EXISTENCE:curator inference:GO:0005730 nucleolus [PMID:15923376]
experiment: EXISTENCE:mutant phenotype:GO:0000454 snoRNA guided rRNA pseudouridine synthesis [PMID:15306656|PMID:15923376]
experiment: EXISTENCE:mutant phenotype:GO:0030559 rRNA pseudouridylation guide activity [PMID:15306656|PMID:15923376]
experiment: EXISTENCE:physical interaction:GO:0031429 box H/ACA snoRNP complex [PMID:15923376]
note: H/ACA box small nucleolar RNA (snoRNA); guides pseudouridylation of large subunit (LSU) rRNA at position U2735 and small subunit (SSU) rRNA at position U466
transcript id: NR_132158.1
SIO_010081: YNCC0012C
subclass of: SO_0000673
so part of: YNCC0012C
location: complement(178610..178798)
location: region:178610-178798:-1
so has part: feature:178610-178798:-1:exon

S000007314
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:178610-178798:-1:exon

YCR032W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: BPH1
locus tag: YCR032W
so part of: sequence
location: <179520..>186023
location: region:179520-186023:1
so has part: feature:179520-186023:1:exon
subclass of: SO_0000010

850398
type: Gene
SIO_000068: ncbigene

position:179520:1
position: 179520
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:186023:1
position: 186023
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:179520-186023:1:exon

YCR032W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: BPH1
locus tag: YCR032W
product: Bph1p
transcript id: NM_001178746.1
SIO_010081: YCR032W
subclass of: SO_0000673
so part of: YCR032W
location: <179520..>186023
location: region:179520-186023:1
so has part: feature:179520-186023:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:179520-186023:1:exon

YCR032W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: BPH1
locus tag: YCR032W
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005770 late endosome [PMID:35343566]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:15296494]
experiment: EXISTENCE:direct assay:GO:0031267 small GTPase binding [PMID:35343566]
experiment: EXISTENCE:mutant phenotype:GO:0006497 protein lipidation [PMID:35343566]
experiment: EXISTENCE:mutant phenotype:GO:0006886 intracellular protein transport [PMID:15296494]
experiment: EXISTENCE:mutant phenotype:GO:0006897 endocytosis [PMID:35343566]
experiment: EXISTENCE:mutant phenotype:GO:0009268 response to pH [PMID:9509574]
experiment: EXISTENCE:mutant phenotype:GO:0031505 fungal-type cell wall organization [PMID:15296494]
note: Endosomal protein involved in endocytosis and autophagy; homologous to Chediak-Higashi syndrome and Beige proteins, both of which are implicated in disease syndromes in human and mouse, respectively, due to defective lysosomal trafficking; mutant phenotype and genetic interactions suggest a role in protein sorting
codon start: 1
product: Bph1p
translation: MNSIINAASKVLRLQDDVKKATIILGDILILQPINHEVEPDVENLVQHELTKIIQGYPIQDNMIINSKKGTVEDDLCELNNYTCFALSKSFDLCHDSRNFNIAQPKRWIQLLETLTDSVSFAVIVQIILTLSNISLINKQTLGKLKKLRIRIFEILSNKNDSWKSTLLQKNLIEWYIFMLSVDCTPLELQNLYLHKELKFCNGILNSLTLQVSDPRSQNYLQFENTYKLFQIQKSSRINNSFLFYIEFNSVTSNRIMTIERHIYLEIKEGQFCISNDNYIIGLFENFEFEAGTLYFIGVLIDHNNRITLYVDGSMINQLTLFENSICQLSTCELGSMICSIKVYRFYLWDGLLTEFAINILQAIGTNYQYTFSKKKEGPEVLSLCQDFLIAKAHLMARPTTEISSTKYIDEIELLEMENIIIDVNPNDILQDFTESSNFTVKFEESTNSKNIPEVGKCYFYRSSNLVSKFVSIDSIRLAFLNMTESGSIDDLFHHVSHLMNLLRNIDILNWFKKDFGFPLFAYTLKQKITQDLSQPLNIQFFNLFLEFCGWDFNDISKSIILDTDAYENIVLNLDLWYMNEDQSSLASGGLEIIRFLFFQISSLMEASIYSKFNSNKFNDMNILEKLCLSYQAVTKRENQNSKFNELSSDLISVFVTLLKSNTDKRHLQWFLHLSYYFIKRKDVRSTEIILQAVDQLFSFYLDQGSDENAKILSEIIPLKLILMIMDQIVENNESNPITCLNILFKVVLTNKPLFKQFYKNDGLKLILTMLCKVGKSYREEIISLLLTYSIGNYTTANEIFSGAEDMIGGISNDKITAKEIIYLAVNFIEWHVINSNASDSSSVLDLNNHILRFVEDLKSLSAVPINESVFDPKKSYVMVSLLDLSIALNESEDISKFKSSSKVISELIKGNIMCALTKYAAYDFEVYMSTFFCHSTEYKLVYPKTVMNNSSYLELSFIVTLLPEILNDLVDSNNNLNLMMLKHPYTMSNLLYFLRKFRPDTSQIVMPKDFYFSSYTCLLHCVIQIDKSSFYHFKNVSKSQLLQDFKICIMNLIYSNTLKQIIWEKEEYEMFSESLMAHQEVLFAHGACDNETVGLLLIFFANRLRDCGYNKAVFNCMKVIIKNKERKLKEVACFFDPANKSEVLEGLSNILSCNNSETMNLITEQYPFFFNNTQQVRFINIVTNILFKNNNFSPISVRQIKNQVYEWKNARSEYVTQNNKKCLILFRKDNTSLDFKIKKSISRYTYNLKTDREENAVFYRNNLNLLIFHLKHTLEIQSNPNSSCKWSSDFAEDFDGMKRRLLPAWEPKYEPLINEEDANQDTITGGNRQRRESGSILSYEFIEHMETLESEPVGDLNENRKILRLLKDNDSIATIWNCSLIIGLEIKEGILIHGSNYLYFVSDYYFSLEDKKILKLSEVSQESRDMTVSLINGPDVKRVSTFLKHEVFVWKLLDITFVTKRPFLLRDVAIELLFKERVSAFFSFYNKRVRDDVLRVLNKIPKHLPADPIFSSVLQEINDRGNSIVARNGIGKASIASKFTSVFSANNSLIDGFEISKKWVRGEISNFYYLLSINILAGRSFNDLTQYPVFPWVIADYESNVLDLENPKTYRDLSKPMGAQSEKRKLQFIERYEALASLENADSAPFHYGTHYSSAMIVSSYLIRLKPFVESFLLLQGGSFGPADRLFSSLERAWSSASSENTTDVRELTPEFFFLPEFLINVNSYDFGTDQSGKKVDDVVLPPWANGDPKVFIQKNREALESPYVSAHLHEWIDLIFGYKQKGDIAVKSVNVFNRLSYPGAVNLDNIDDENERRAITGIIHNFGQTPLQIFQEPHPEKIACNVQQLTTEVWRKVPMKPIFEKTIFNLNEKNRSVDYVIHDPSYFDSLYWRGFAFPNLFFRTEESLVSLRIVHKNWLKIGLDIFKKTHMAQITSFAYWKLGEFITGDKNGLIKVWKYRKDKHSVSGNLENKKTMFGHLCELKEMRCYHDYNTLLTLDISG…
SIO_010081: YCR032W
subclass of: SO_0000673
so part of: YCR032W
location: 179520..186023
location: region:179520-186023:1
so has part: feature:179520-186023:1:exon

NP_009961.2
type: Protein
SIO_000068: ncbiprotein

S000000628
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:179520-186023:1:exon

YCR033W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SNT1
locus tag: YCR033W
so part of: sequence
location: <186489..>190169
location: region:186489-190169:1
so has part: feature:186489-190169:1:exon
subclass of: SO_0000010

850399
type: Gene
SIO_000068: ncbigene

position:186489:1
position: 186489
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:190169:1
position: 190169
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:186489-190169:1:exon

YCR033W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SNT1
locus tag: YCR033W
product: Snt1p
transcript id: NM_001178747.1
SIO_010081: YCR033W
subclass of: SO_0000673
so part of: YCR033W
location: <186489..>190169
location: region:186489-190169:1
so has part: feature:186489-190169:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:186489-190169:1:exon

YCR033W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SNT1
locus tag: YCR033W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0034967 Set3 complex [PMID:11711434]
experiment: EXISTENCE:direct assay:GO:0070210 Rpd3L-Expanded complex [PMID:19040720]
experiment: EXISTENCE:mutant phenotype:GO:0006355 regulation of DNA-templated transcription [PMID:19379692]
experiment: EXISTENCE:mutant phenotype:GO:0032874 positive regulation of stress-activated MAPK cascade [PMID:18487345]
note: Set3C histone deacetylase scaffold; can act as prion [ESI+] (Expressed Subtelomeric Information) that drives emergence and transgenerational inheritance of activated chromatin state; prion conformer is triggered by transient Snt1p phosphorylation upon cell cycle arrest; [ESI+] reshapes the activity Set3C, recruiting RNAPII, interfering with Rap1p binding to activate genes in otherwise repressed subtelomeric domains; relocalizes to cytosol in response to hypoxia
codon start: 1
product: Snt1p
translation: MGYPPPTRRLGDKKRYHYSNNPNRRHPSAVYSKNSFPKSSNNGFVSSPTADNSTNPSVTPSTASVPLPTAAPGSTFGIEAPRPSRYDPSSVSRPSSSSYSSTRKIGSRYNPDVERSSSTTSSTPESMNTSTITHTNTDIGNSRYSRKTMSRYNPQSTSSTNVTHFPSALSNAPPFYVANGSSRRPRSMDDYSPDVTNKLETNNVSSVNNNSPHSYYSRSNKWRSIGTPSRPPFDNHVGNMTTTSNTNSIHQREPFWKANSTTILKSTHSQSSPSLHTKKFHDANKLDKPEASVKVETPSKDETKAISYHDNNFPPRKSVSKPNAPLEPDNIKVGEEDALGKKEVHKSGREIAKEHPTPVKMKEHDELEARAKKVSKINIDGKQDEIWTTAKTVASAVEVSKESQKELTRSVERKESPEIRDYERAYDPKALKTDVTKLTVDNDNKSYEEPLEKVEGCIFPLPKAETRLWELKNQKRNKIISEQKYLLKKAIRNFSEYPFYAQNKLIHQQATGLILTKIISKIKKEEHLKKINLKHDYFDLQKKYEKECEILTKLSENLRKEEIENKRKEHELMEQKRREEGIETEKEKSLRHPSSSSSSRRRNRADFVDDAEMENVLLQIDPNYKHYQAAATIPPLILDPIRKHSYKFCDVNNLVTDKKLWASRILKDASDNFTDHEHSLFLEGYLIHPKKFGKISHYMGGLRSPEECVLHYYRTKKTVNYKQLLIDKNKKRKMSAAAKRRKRKERSNDEEVEVDESKEESTNTIEKEEKSENNAEENVQPVLVQGSEVKGDPLGTPEKVENMIEQRGEEFAGELENAERVNDLKRAHDEVGEESNKSSVIETNNGVQIMDPKGAVQNGYYPEETKELDFSLENALQRKKHKSAPEHKTSYWSVRESQLFPELLKEFGSQWSLISEKLGTKSTTMVRNYYQRNAARNGWKLLVDETDLKRDGTSSESVQQSQILIQPERPNINAYSNIPPQQRPALGYFVGQPTHGHNTSISSIDGSIRPFGPDFHRDTFSKISAPLTTLPPPRLPSIQFPRSEMAEPTVTDLRNRPLDHIDTLADAASSVTNNQNFSNERNAIDIGRKSTTISNLLNNSDRSMKSSFQSASRHEAQLEDTPSMNNIVVQEIKPNITTPRSSSISALLNPVNGNGQSNPDGRPLLPFQHAISQGTPTFPLPAPRTSPISRAPPKFNFSNDPLAALAAVASAPDAMSSFLSKKENNN
SIO_010081: YCR033W
subclass of: SO_0000673
so part of: YCR033W
location: 186489..190169
location: region:186489-190169:1
so has part: feature:186489-190169:1:exon

NP_009962.2
type: Protein
SIO_000068: ncbiprotein

S000000629
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:186489-190169:1:exon

YCR034W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: FEN1
alternative label: GNS1
alternative label: VBM2
gene: ELO2
locus tag: YCR034W
gene synonym: FEN1; GNS1; VBM2
so part of: sequence
location: <190592..>191635
location: region:190592-191635:1
so has part: feature:190592-191635:1:exon
subclass of: SO_0000010

850400
type: Gene
SIO_000068: ncbigene

position:190592:1
position: 190592
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:191635:1
position: 191635
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:190592-191635:1:exon

YCR034W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: FEN1
alternative label: GNS1
alternative label: VBM2
gene: ELO2
locus tag: YCR034W
gene synonym: FEN1; GNS1; VBM2
product: fatty acid elongase ELO2
transcript id: NM_001178748.1
SIO_010081: YCR034W
subclass of: SO_0000673
so part of: YCR034W
location: <190592..>191635
location: region:190592-191635:1
so has part: feature:190592-191635:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:190592-191635:1:exon

YCR034W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: FEN1
alternative label: GNS1
alternative label: VBM2
gene: ELO2
locus tag: YCR034W
gene synonym: FEN1; GNS1; VBM2
EC number: 2.3.1.199
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:12087109]
experiment: EXISTENCE:genetic interaction:GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway [PMID:23325927]
experiment: EXISTENCE:mutant phenotype:GO:0009922 fatty acid elongase activity [PMID:12684876]
experiment: EXISTENCE:mutant phenotype:GO:0016192 vesicle-mediated transport [PMID:9832547]
experiment: EXISTENCE:mutant phenotype:GO:0030148 sphingolipid biosynthetic process [PMID:9211877]
experiment: EXISTENCE:mutant phenotype:GO:0030497 fatty acid elongation [PMID:9211877]
experiment: EXISTENCE:mutant phenotype:GO:0042761 very long-chain fatty acid biosynthetic process [PMID:23325927]
note: Fatty acid elongase, involved in sphingolipid biosynthesis; acts on fatty acids of up to 24 carbons in length; mutations have regulatory effects on 1,3-beta-glucan synthase, vacuolar ATPase, and the secretory pathway; ELO2 has a paralog, ELO1, that arose from the whole genome duplication; lethality of the elo2 elo3 double null mutation is functionally complemented by human ELOVL1 and weakly complemented by human ELOVL3 or ELOV7
codon start: 1
product: fatty acid elongase ELO2
translation: MNSLVTQYAAPLFERYPQLHDYLPTLERPFFNISLWEHFDDVVTRVTNGRFVPSEFQFIAGELPLSTLPPVLYAITAYYVIIFGGRFLLSKSKPFKLNGLFQLHNLVLTSLSLTLLLLMVEQLVPIIVQHGLYFAICNIGAWTQPLVTLYYMNYIVKFIEFIDTFFLVLKHKKLTFLHTYHHGATALLCYTQLMGTTSISWVPISLNLGVHVVMYWYYFLAARGIRVWWKEWVTRFQIIQFVLDIGFIYFAVYQKAVHLYFPILPHCGDCVGSTTATFAGCAIISSYLVLFISFYINVYKRKGTKTSRVVKRAHGGVAAKVNEYVNVDLKNVPTPSPSPKPQHRRKR
SIO_010081: YCR034W
subclass of: SO_0000673
so part of: YCR034W
location: 190592..191635
location: region:190592-191635:1
so has part: feature:190592-191635:1:exon

NP_009963.1
type: Protein
SIO_000068: ncbiprotein

S000000630
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:190592-191635:1:exon

YCR035C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RRP43
locus tag: YCR035C
so part of: sequence
location: complement(<191834..>193018)
location: region:191834-193018:-1
so has part: feature:191834-193018:-1:exon
subclass of: SO_0000010

850401
type: Gene
SIO_000068: ncbigene

position:191834:-1
position: 191834
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:193018:-1
position: 193018
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:191834-193018:-1:exon

YCR035C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RRP43
locus tag: YCR035C
product: exosome non-catalytic core subunit RRP43
transcript id: NM_001178749.1
SIO_010081: YCR035C
subclass of: SO_0000673
so part of: YCR035C
location: complement(<191834..>193018)
location: region:191834-193018:-1
so has part: feature:191834-193018:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:191834-193018:-1:exon

YCR035C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RRP43
locus tag: YCR035C
experiment: EXISTENCE:curator inference:GO:0043628 regulatory ncRNA 3'-end processing [PMID:10465791]
experiment: EXISTENCE:curator inference:GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay [PMID:10465791]
experiment: EXISTENCE:curator inference:GO:0070481 nuclear-transcribed mRNA catabolic process, non-stop decay [PMID:10465791]
experiment: EXISTENCE:curator inference:GO:0070651 nonfunctional rRNA decay [PMID:10465791]
experiment: EXISTENCE:curator inference:GO:0071051 polyadenylation-dependent snoRNA 3'-end processing [PMID:10465791]
experiment: EXISTENCE:direct assay:GO:0000176 nuclear exosome (RNase complex) [PMID:10465791|PMID:19046973]
experiment: EXISTENCE:direct assay:GO:0000177 cytoplasmic exosome (RNase complex) [PMID:19046973|PMID:10465791]
experiment: EXISTENCE:direct assay:GO:0005654 nucleoplasm [PMID:9891085]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:9891085]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:9891085]
experiment: EXISTENCE:direct assay:GO:0071038 nuclear polyadenylation-dependent tRNA catabolic process [PMID:15828860|PMID:17643380]
experiment: EXISTENCE:mutant phenotype:GO:0000467 exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:10508172|PMID:12364597|PMID:9390555]
experiment: EXISTENCE:mutant phenotype:GO:0006397 mRNA processing [PMID:27385342]
experiment: EXISTENCE:mutant phenotype:GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' [PMID:12364597]
experiment: EXISTENCE:mutant phenotype:GO:0071035 nuclear polyadenylation-dependent rRNA catabolic process [PMID:18940861]
experiment: EXISTENCE:mutant phenotype:GO:0071042 nuclear polyadenylation-dependent mRNA catabolic process [PMID:19369424]
note: Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hRrp43p (OIP2, EXOSC8); protein abundance increases in response to DNA replication stress
codon start: 1
product: exosome non-catalytic core subunit RRP43
translation: MAESTTLETIEIHPITFPPEVLARISPELSLQRHLSLGIRPCLRKYEEFRDVAIENNTLSRYADAGNIDTKNNILGSNVLKSGKTIVITSITGGIIEETSAAIKDLDDFGEEELFEVTKEEDIIANYASVYPVVEVERGRVGACTDEEMTISQKLHDSILHSRILPKKALKVKAGVRSANEDGTFSVLYPDELEDDTLNETNLKMKRKWSYVLYAKIVVLSRTGPVFDLCWNSLMYALQSVKLPRAFIDERASDLRMTIRTRGRSATIRETYEIICDQTKSVPLMINAKNIAFASNYGIVELDPECQLQNSDNSEEEEVDIDMDKLNTVLIADLDTEAEETSIHSTISILAAPSGNYKQLTLVGGGAKITPEMIKRSLLLSRVRADDLSTRFNI
SIO_010081: YCR035C
subclass of: SO_0000673
so part of: YCR035C
location: complement(191834..193018)
location: region:191834-193018:-1
so has part: feature:191834-193018:-1:exon

NP_009964.2
type: Protein
SIO_000068: ncbiprotein

S000000631
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:191834-193018:-1:exon

YCR036W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RBK1
locus tag: YCR036W
so part of: sequence
location: <193297..>194298
location: region:193297-194298:1
so has part: feature:193297-194298:1:exon
subclass of: SO_0000010

850402
type: Gene
SIO_000068: ncbigene

position:193297:1
position: 193297
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:194298:1
position: 194298
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:193297-194298:1:exon

YCR036W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RBK1
locus tag: YCR036W
product: putative ribokinase
transcript id: NM_001178750.1
SIO_010081: YCR036W
subclass of: SO_0000673
so part of: YCR036W
location: <193297..>194298
location: region:193297-194298:1
so has part: feature:193297-194298:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:193297-194298:1:exon

YCR036W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RBK1
locus tag: YCR036W
EC number: 2.7.1.15
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
note: Ribokinase, phosphorylates ribose to ribose-5-phosphate; required for recycling ribose during nucleotide metabolism
codon start: 1
product: putative ribokinase
translation: MGITVIGSLNYDLDTFTDRLPNAGETFRANHFETHAGGKGLNQAAAIGKLKNPSSRYSVRMIGNVGNDTFGKQLKDTLSDCGVDITHVGTYEGINTGTATILIEEKAGGQNRILIVEGANSKTIYDPKQLCEIFPEGKEEEEYVVFQHEIPDPLSIIKWIHANRPNFQIVYNPSPFKAMPKKDWELVDLLVVNEIEGLQIVESVFDNELVEEIREKIKDDFLGEYRKICELLYEKLMNRKKRGIVVMTLGSRGVLFCSHESPEVQFLPAIQNVSVVDTTGAGDTFLGGLVTQLYQGETLSTAIKFSTLASSLTIQRKGAAESMPLYKDVQKDA
SIO_010081: YCR036W
subclass of: SO_0000673
so part of: YCR036W
location: 193297..194298
location: region:193297-194298:1
so has part: feature:193297-194298:1:exon

NP_009965.2
type: Protein
SIO_000068: ncbiprotein

S000000632
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:193297-194298:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS313; Autonomously Replicating Sequence on Chromosome III
so part of: sequence
location: 194308..194367
location: region:194308-194367:1
so has part: feature:194308-194367:1:region

S000028488
type: SGD
SIO_000068: sgd

position:194308:1
position: 194308
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:194367:1
position: 194367
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:194308-194367:1:region

YCR037C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PHO87
locus tag: YCR037C
so part of: sequence
location: complement(<194414..>197185)
location: region:194414-197185:-1
so has part: feature:194414-197185:-1:exon
subclass of: SO_0000010

850403
type: Gene
SIO_000068: ncbigene

position:194414:-1
position: 194414
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:197185:-1
position: 197185
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:194414-197185:-1:exon

YCR037C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PHO87
locus tag: YCR037C
product: SPX domain-containing inorganic phosphate transporter
transcript id: NM_001178751.1
SIO_010081: YCR037C
subclass of: SO_0000673
so part of: YCR037C
location: complement(<194414..>197185)
location: region:194414-197185:-1
so has part: feature:194414-197185:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:194414-197185:-1:exon

YCR037C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PHO87
locus tag: YCR037C
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:21143198]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0005315 inorganic phosphate transmembrane transporter activity [PMID:11779791]
experiment: EXISTENCE:genetic interaction:GO:0006817 phosphate ion transport [PMID:11779791]
experiment: EXISTENCE:genetic interaction:GO:2000185 regulation of phosphate transmembrane transport [PMID:12821119]
experiment: EXISTENCE:mutant phenotype:GO:0006797 polyphosphate metabolic process [PMID:17804816]
experiment: EXISTENCE:mutant phenotype:GO:0097080 plasma membrane selenite transport [PMID:20688911]
note: Low-affinity inorganic phosphate (Pi) transporter; acts upstream of Pho81p in regulation of PHO pathway; targeted to vacuole via AP-3 pathway; expression is independent of Pi concentration and Pho4p activity; contains 12 membrane-spanning segments; PHO87 has a paralog, PHO90, that arose from the whole genome duplication
codon start: 1
product: SPX domain-containing inorganic phosphate transporter
translation: MRFSHFLKYNAVPEWQNHYLDYNELKNLIYTLQTDELKQETPTGDLNDDADSQTPGPIADIESNIAAGEPSSSKRRFTHKLKRKLFGSKTPSGSKRGDSDEKAIDGNNINEETIELDELSPQGKTTSFNKNFIRKKFFESRSSSVSSEGKTLFSSYDTFVTNLSDEKLKVDDFYKRMEAKFYERFDHLINDLEKEGIVTRLNETFNPEIQALPPLREIISGTSETHSSNNPFEIHSSNIDSELRNRFDYSEEEMDEDDDVDVFADTTDNTALLNYSQFNIKSQKKSLLKQTIINLYIDLCQLKSFIELNRMGFSKITKKSDKVLHMNTRQELIESEEFFKDTYIFQHETLSSLNSKIAQLIEFYAVLMGQPGNVDSCKQELKSYLHDHIVWERSNTWKDMLGLSSQNNDIITIEDEAEKLMQEKLQIEYFKYPLPKPINLKFTKIENLAVPKLFFGKRAMKIGFIIIVTGVLLGVKTFNDPVEHRCMALVECCAFLWASEAIPLHITGLLVPLLTVLFRVLKDDDGKVMGAAAASTEILGTMWSSTIMILLAGFTLGEALSQYNVAKVLASWLLALAGTKPRNVLLMAMSVVFFLSMWISNVASPVLTYSLLTPLLDPLDYTSPFAKALVMGVALSADIGGMASPISSPQNIISMQYLKPYGIGWGQFFAVALPTGILSMLCSWALMILTFKIGKTKLEKFKPIRTRFTIKQYFIIIVTIATILLWCVESQIESAFGSSGEIAVIPIVLFFGTGLLSTKDFNTFPWSIVVLAMGGIALGKAVSSSGLLVTIARALQKKIQNDGVFAILCIFGILMLVVGTFVSHTVSAIIIIPLVQEVGDKLSDPKAAPILVFGCALLASCGMGLASSGFPNVTAISMTDKKGNRWLTVGAFISRGVPASLLAFVCVITLGYGISSSVLKGST
SIO_010081: YCR037C
subclass of: SO_0000673
so part of: YCR037C
location: complement(194414..197185)
location: region:194414-197185:-1
so has part: feature:194414-197185:-1:exon

NP_009966.2
type: Protein
SIO_000068: ncbiprotein

S000000633
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:194414-197185:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS314; Autonomously Replicating Sequence on Chromosome III; active in <10% of cell cycles
so part of: sequence
location: 197460..197598
location: region:197460-197598:1
so has part: feature:197460-197598:1:region

S000028489
type: SGD
SIO_000068: sgd

position:197460:1
position: 197460
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:197598:1
position: 197598
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:197460-197598:1:region

YCR038C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: BUD5
locus tag: YCR038C
so part of: sequence
location: complement(<197621..>199549)
location: region:197621-199549:-1
so has part: feature:197621-199549:-1:exon
subclass of: SO_0000010

850405
type: Gene
SIO_000068: ncbigene

position:197621:-1
position: 197621
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:199549:-1
position: 199549
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:197621-199549:-1:exon

YCR038C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: BUD5
locus tag: YCR038C
product: Ras family guanine nucleotide exchange factor BUD5
transcript id: NM_001178752.1
SIO_010081: YCR038C
subclass of: SO_0000673
so part of: YCR038C
location: complement(<197621..>199549)
location: region:197621-199549:-1
so has part: feature:197621-199549:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:197621-199549:-1:exon

YCR038C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: BUD5
locus tag: YCR038C
experiment: EXISTENCE:direct assay:GO:0000131 incipient cellular bud site [PMID:11313501]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:11313501]
experiment: EXISTENCE:genetic interaction:GO:0005085 guanyl-nucleotide exchange factor activity [PMID:11589573|PMID:8234337]
experiment: EXISTENCE:mutant phenotype:GO:0007120 axial cellular bud site selection [PMID:1905981]
experiment: EXISTENCE:mutant phenotype:GO:0007121 bipolar cellular bud site selection [PMID:1905981]
note: GTP/GDP exchange factor for Rsr1p (Bud1p); required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types
codon start: 1
product: Ras family guanine nucleotide exchange factor BUD5
translation: MSPKNKYVYICVEYIYIYFAKIHKQSTLSSDTTKMFVLIDNVLAYLLEQDDLFVTARFAIQGQIVSRRVNKIHISNITDVLLQQFISHTLPYNDNIVPKKILDSMRTAVRQLLEATACVSRECPLVKRSQDIKRARKRLLSDWYRLGADANMDAVLLVVNSAWRFLAVWRPFVNSIQHATQELYQNIAHYLLHGNVNIQRVTALIQLVMGQDDLLFSMDDVLQEVFRIQLYLNKMLPHNSHKWQKPSPFDSANLLLNFRDWTTDNALLQELLLSYPTINKNKHKNHSVPRLIQIWVESYWQDSETTLKDILNFWYSHLAEYYEYQELFADIVQLFINKKRTRQLKIHYIGLTDKEIEENKPPLDYENLFLQYEIDKTNANDELCGATDLSDLLFQWKQGELLEVEAFALNVSPWSLAKTLTLLESSLYLDIETIEFTRHFKHNDTTIDSVFTLSNQLSSYVLETTLQQTHTISYWLQVALSCLYLRNLNSLASIITSLQNHSIERLSLPIDVKSDHLFQRLKVVVHPNNNYNVYRRTIKHIFHSQLPCVPFTSLLIRDITFIRDGNDTFTKDGNNVNMQKFNQITKIVAFAQYLQQKQYEDIHCSNTTARSLLGAMIKVHTLYNDNKDRAYQVSIAKVPRLT
SIO_010081: YCR038C
subclass of: SO_0000673
so part of: YCR038C
location: complement(197621..199549)
location: region:197621-199549:-1
so has part: feature:197621-199549:-1:exon

NP_009967.2
type: Protein
SIO_000068: ncbiprotein

S000000634
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:197621-199549:-1:exon

misc_feature
type: Miscellaneous Feature
subclass of: SO_0000001
RO_0002162: 559292
note: MATALPHA; Mating type locus; note that the systematic sequence in SGD contains MATalpha sequences
so part of: sequence
location: 198671..201177
location: region:198671-201177:1
so has part: feature:198671-201177:1:region

S000029699
type: SGD
SIO_000068: sgd

position:198671:1
position: 198671
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:201177:1
position: 201177
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:198671-201177:1:region

YCR039C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ALPHA2
gene: MATALPHA2
locus tag: YCR039C
gene synonym: ALPHA2
so part of: sequence
location: complement(<199546..>200178)
location: region:199546-200178:-1
so has part: feature:199546-200178:-1:exon
subclass of: SO_0000010

850406
type: Gene
SIO_000068: ncbigene

position:199546:-1
position: 199546
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:200178:-1
position: 200178
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:199546-200178:-1:exon

YCR039C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ALPHA2
gene: MATALPHA2
locus tag: YCR039C
gene synonym: ALPHA2
product: homeodomain mating type protein alpha2
transcript id: NM_001178753.1
SIO_010081: YCR039C
subclass of: SO_0000673
so part of: YCR039C
location: complement(<199546..>200178)
location: region:199546-200178:-1
so has part: feature:199546-200178:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:199546-200178:-1:exon

YCR039C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ALPHA2
gene: MATALPHA2
locus tag: YCR039C
gene synonym: ALPHA2
experiment: EXISTENCE:direct assay:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:3893743]
experiment: EXISTENCE:direct assay:GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific [PMID:15598821]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:1976249]
experiment: EXISTENCE:direct assay:GO:0008301 DNA binding, bending [PMID:7569974|PMID:7739902]
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:3893743]
note: Homeobox-domain protein; with Mcm1p, represses a-specific genes in haploids; acts with A1p to repress transcription of haploid-specific genes in diploids; one of two genes encoded by the MATalpha mating type cassette
codon start: 1
product: homeodomain mating type protein alpha2
translation: MNKIPIKDLLNPQITDEFKSSILDINKKLFSICCNLPKLPESVTTEEEVELRDILGFLSRANKNRKISDEEKKLLQTTSQLTTTITVLLKEMRSIENDRSNYQLTQKNKSADGLVFNVVTQDMINKSTKPYRGHRFTKENVRILESWFAKNIENPYLDTKGLENLMKNTSLSRIQIKNWVSNRRRKEKTITIAPELADLLSGEPLAKKKE
SIO_010081: YCR039C
subclass of: SO_0000673
so part of: YCR039C
location: complement(199546..200178)
location: region:199546-200178:-1
so has part: feature:199546-200178:-1:exon

NP_009868.3
type: Protein
SIO_000068: ncbiprotein

S000000635
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:199546-200178:-1:exon

YCR040W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ALPHA1
gene: MATALPHA1
locus tag: YCR040W
gene synonym: ALPHA1
so part of: sequence
location: <200442..>200969
location: region:200442-200969:1
so has part: feature:200442-200969:1:exon
subclass of: SO_0000010

850407
type: Gene
SIO_000068: ncbigene

position:200442:1
position: 200442
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:200969:1
position: 200969
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:200442-200969:1:exon

YCR040W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ALPHA1
gene: MATALPHA1
locus tag: YCR040W
gene synonym: ALPHA1
product: transcriptional co-activator mating type protein alpha
transcript id: NM_001178754.1
SIO_010081: YCR040W
subclass of: SO_0000673
so part of: YCR040W
location: <200442..>200969
location: region:200442-200969:1
so has part: feature:200442-200969:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:200442-200969:1:exon

YCR040W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ALPHA1
gene: MATALPHA1
locus tag: YCR040W
gene synonym: ALPHA1
experiment: EXISTENCE:curator inference:GO:0005634 nucleus [PMID:6337727]
experiment: EXISTENCE:direct assay:GO:0008301 DNA binding, bending [PMID:15118075]
experiment: EXISTENCE:mutant phenotype:GO:0003713 transcription coactivator activity [PMID:6337727]
experiment: EXISTENCE:mutant phenotype:GO:0006357 regulation of transcription by RNA polymerase II [PMID:6337727]
experiment: EXISTENCE:mutant phenotype:GO:0007532 regulation of mating-type specific transcription, DNA-templated [PMID:6337727]
note: Transcriptional co-activator that regulates mating-type-specific genes; targets the transcription factor Mcm1p to the promoters of alpha-specific genes; one of two genes encoded by the MATalpha mating type cassette
codon start: 1
product: transcriptional co-activator mating type protein alpha
translation: MFTSKPAFKIKNKASKSYRNTAVSKKLKEKRLAEHVRPSCFNIIRPLKKDIQIPVPSSRFLNKIQIHRIASGSQNTQFRQFNKTSIKSSKKYLNSFMAFRAYYSQFGSGVKQNVLSSLLAEEWHADKMQHGIWDYFAQQYNFINPGFGFVEWLTNNYAEVRGDGYWEDVFVHLAL
SIO_010081: YCR040W
subclass of: SO_0000673
so part of: YCR040W
location: 200442..200969
location: region:200442-200969:1
so has part: feature:200442-200969:1:exon

NP_009869.3
type: Protein
SIO_000068: ncbiprotein

S000000636
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:200442-200969:1:exon

YCR041W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCR041W
so part of: sequence
location: <200911..>201243
location: region:200911-201243:1
so has part: feature:200911-201243:1:exon
subclass of: SO_0000010

850408
type: Gene
SIO_000068: ncbigene

position:200911:1
position: 200911
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:201243:1
position: 201243
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:200911-201243:1:exon

YCR041W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCR041W
product: uncharacterized protein
transcript id: NM_001310667.1
SIO_010081: YCR041W
subclass of: SO_0000673
so part of: YCR041W
location: <200911..>201243
location: region:200911-201243:1
so has part: feature:200911-201243:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:200911-201243:1:exon

YCR041W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YCR041W
note: hypothetical protein; overexpression suppresses the high-frequency loss of mini-chromosomes, probably by increasing the rate of proper chromosome segregation; translated gene product of YCR041W, but not its transcript, is responsible for suppression; suppression ability of YCR041W is completely dependent on silencing protein Sir4p
codon start: 1
product: uncharacterized protein
translation: MLKYVVTDIGKMCLYIWPYRVWSWRRLFIFRVLNVVSIAILFETPHRLALVPNVCLYTHMAIPLSTCLFCLCLCICIKYDITQTQANNQFLASFFVLILTINDLDVTFVI
SIO_010081: YCR041W
subclass of: SO_0000673
so part of: YCR041W
location: 200911..201243
location: region:200911-201243:1
so has part: feature:200911-201243:1:exon

NP_001297596.1
type: Protein
SIO_000068: ncbiprotein

S000000637
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:200911-201243:1:exon

YCR042C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: TAF150
alternative label: TSM1
gene: TAF2
locus tag: YCR042C
gene synonym: TAF150; TSM1
so part of: sequence
location: complement(<201174..>205397)
location: region:201174-205397:-1
so has part: feature:201174-205397:-1:exon
subclass of: SO_0000010

850409
type: Gene
SIO_000068: ncbigene

position:201174:-1
position: 201174
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:205397:-1
position: 205397
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:201174-205397:-1:exon

YCR042C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: TAF150
alternative label: TSM1
gene: TAF2
locus tag: YCR042C
gene synonym: TAF150; TSM1
product: Taf2p
transcript id: NM_001178756.1
SIO_010081: YCR042C
subclass of: SO_0000673
so part of: YCR042C
location: complement(<201174..>205397)
location: region:201174-205397:-1
so has part: feature:201174-205397:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:201174-205397:-1:exon

YCR042C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: TAF150
alternative label: TSM1
gene: TAF2
locus tag: YCR042C
gene synonym: TAF150; TSM1
experiment: EXISTENCE:curator inference:GO:0016251 RNA polymerase II general transcription initiation factor activity [PMID:15448131]
experiment: EXISTENCE:curator inference:GO:0051123 RNA polymerase II preinitiation complex assembly [PMID:10788514]
experiment: EXISTENCE:direct assay:GO:0003682 chromatin binding [PMID:10818000|PMID:12600943]
experiment: EXISTENCE:direct assay:GO:0005669 transcription factor TFIID complex [PMID:10788514|PMID:15448131]
experiment: EXISTENCE:direct assay:GO:0006366 transcription by RNA polymerase II [PMID:12138208|PMID:15448131]
note: TFIID subunit (150 kDa); involved in RNA polymerase II transcription initiation
codon start: 1
product: Taf2p
translation: MMSFSKNATPRAIVSESSTLHEMKFRNFRVAHEKISLDIDLATHCITGSATIIIIPLIQNLEYVTFDCKEMTIKDVLVENRRCDQFIHDDPLQTNLNGLTSQNVLYSDNSIEQSHFLRSKFASLNEYPETDSKSQLTIKIPSSIKISLEDANALSNYTPITPSIKTTPGFQESVFTPITLQIEYEIRNPKSGIKFDTVYADKPWLWNVYTSNGEICSSASYWVPCVDLLDEKSTWELEFSVPRLVKNIGTSKLIGQNGEESEKEKEDTPEHDEEEEGKPARVIKDEDKDSNLKNDEEGKNSKSKDAQDNDEEEEEGESDEEEEEGEEERRNIEESNNPSLRDVIVCCSEYSNIKELPHPIDLTKKKCIFQIINPVAPHHIGWAIGAFNSWSLPLISPPSVDAEDEVEEDKLRENVVDNVNDTMDDDIGSDIIPIQIFTLPTQETDELTVINSTVVCQKIIDFYSKEFGSYPFTCYSMVFLPTAPSKHMDFAALGICNTRLLYPLEVIDKAFSTTNELAWALANQWSCVNITPLDMNDYWCCLGIAGYMVFQVTKKLMGNNTYKYQLKRNSEAIVEQDFEKPPIGSTFTGSSRPISWSSKDLSFIQLKAPMILHILDRRMTKTERSFGMSRVLPKIFLQAMSGDLPNNSLTSSHFQHVCERVNKSKLENFFNEWVYGSGVPILRVTQRFNRKRMVIELGIRQVQDEELGHEKVVGEEGFFKSALDHLEHPDLNRTECFTGSMTIRIHEHDGTPYEHIVEIKDTFTKIDIQYNTKYRRLRKRGGGANDENGVENNNEEKPIVVDVNCLGNVYMSPEECSRFSLTEFNRTSESNELLKQNEAFEWIRIDSDLEWICQMHINQPDYMFSSQLRQDGDIEAQLEAIRYYEDVVVNGGVKSLVYSSILFRTAIDERYFFGIRLAACEALSKYVYDPDFTGGVKHLIQIFQILFCLEDSNIPKSNNFENPKLYFLQCNIPKYLAKVKNENGKCPKLVKQFLLDILVYNENGENKYSDDAYVRSLIENVVKVALNEYKDKAYMEKVKTQLLRYENLVNWLSSYESLIKTTIMYAKYKLHKVGAYDFTELTGMIMHTLTLGINNGDISRESFQNEFLMVLKIMLLEGGLKNKDALVLFTEILCFHEDSYIRDKSVDVLSECVNLVVMDGSLDTISDDIKSSVQSVHNEVKNIKSEDDIELFLSGHYVDDMKIKIEKIGRQNISGLIQICRDMFKGYSPLKILLWDVLNLPVLSLYQRKQIHDLVRVMYTLINSFVVRLETPRERRLVAKMNSNEEGKLDIVIKRESILKVHIKKEVTSTVEAPKKANKIKISLKGDKPVRKVEKQIVKPKVTSKQRKVKSHVNRMGSLPLRFVKIQQQPRVMVHLSSVPYSQFVQITKVTSRSFMVKIRTKNDAKN
SIO_010081: YCR042C
subclass of: SO_0000673
so part of: YCR042C
location: complement(201174..205397)
location: region:201174-205397:-1
so has part: feature:201174-205397:-1:exon

NP_009971.1
type: Protein
SIO_000068: ncbiprotein

S000000638
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:201174-205397:-1:exon

YCR043C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCR043C
so part of: sequence
location: complement(<206261..>206644)
location: region:206261-206644:-1
so has part: feature:206261-206644:-1:exon
subclass of: SO_0000010

850410
type: Gene
SIO_000068: ncbigene

position:206261:-1
position: 206261
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:206644:-1
position: 206644
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:206261-206644:-1:exon

YCR043C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCR043C
product: uncharacterized protein
transcript id: NM_001178757.1
SIO_010081: YCR043C
subclass of: SO_0000673
so part of: YCR043C
location: complement(<206261..>206644)
location: region:206261-206644:-1
so has part: feature:206261-206644:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:206261-206644:-1:exon

YCR043C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YCR043C
experiment: EXISTENCE:direct assay:GO:0005794 Golgi apparatus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:19053807]
note: hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to the Golgi apparatus; YCR043C is not an essential gene
codon start: 1
product: uncharacterized protein
translation: MIPAPLDASLLREHAFQGTNDLSTVLSPSTFTDEGGYKPVLKYGLGYFNYGLVIDDEVYDYSVCDIIRGHVYDHFWCYFCCFMILFTIWLISLNWCPSSKKSKFDWSKKKDDFKMEGGDLEYQHVKI
SIO_010081: YCR043C
subclass of: SO_0000673
so part of: YCR043C
location: complement(206261..206644)
location: region:206261-206644:-1
so has part: feature:206261-206644:-1:exon

NP_009972.1
type: Protein
SIO_000068: ncbiprotein

S000000639
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:206261-206644:-1:exon

YCR044C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: COS16
gene: PER1
locus tag: YCR044C
gene synonym: COS16
so part of: sequence
location: complement(<206877..>207950)
location: region:206877-207950:-1
so has part: feature:206877-207950:-1:exon
subclass of: SO_0000010

850411
type: Gene
SIO_000068: ncbigene

position:206877:-1
position: 206877
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:207950:-1
position: 207950
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:206877-207950:-1:exon

YCR044C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: COS16
gene: PER1
locus tag: YCR044C
gene synonym: COS16
product: Per1p
transcript id: NM_001178758.1
SIO_010081: YCR044C
subclass of: SO_0000673
so part of: YCR044C
location: complement(<206877..>207950)
location: region:206877-207950:-1
so has part: feature:206877-207950:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:206877-207950:-1:exon

YCR044C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: COS16
gene: PER1
locus tag: YCR044C
gene synonym: COS16
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:9560393]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:17021251]
experiment: EXISTENCE:mutant phenotype:GO:0006506 GPI anchor biosynthetic process [PMID:17021251]
experiment: EXISTENCE:mutant phenotype:GO:0030026 cellular manganese ion homeostasis [PMID:9560393]
note: Protein of the endoplasmic reticulum; required for GPI-phospholipase A2 activity that remodels the GPI anchor as a prerequisite for association of GPI-anchored proteins with lipid rafts; functionally complemented by human ortholog PERLD1
codon start: 1
product: Per1p
translation: MRLAVVVTLLVHCFLVTCSPGDNLDEFIDCTYACEYNRRCPNSQINYIDPETNMFHDIEFFDTPPLYSKLLFWDCISDCDYQCQHIITRWRIDEEEEIYQFHGKWPFLRVLGTQEFFSTIFSIGNFIPHYKGFVKFSRIIREEGDRRRKNSRSILIWNYLYVTVAGMLAWTASSVFHCRDLIITEKLDYFFAGLTVLTGFHAIFARMTSMFLYPKIAQAFTASVAAIFALHILRLYVDWSYTYNMRFNIFFGVLQYILLIMLSCQNYHALQKQKLMGEFKKTAYSSFKRQIFKLCVIPILLVIVTTMAMSLELFDFFSYEWQIDAHALWHLCTIWPSWVLYDFFLEDYAYWGNRQLY
SIO_010081: YCR044C
subclass of: SO_0000673
so part of: YCR044C
location: complement(206877..207950)
location: region:206877-207950:-1
so has part: feature:206877-207950:-1:exon

NP_009973.1
type: Protein
SIO_000068: ncbiprotein

S000000640
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:206877-207950:-1:exon

YCR045C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: OSW3
gene: RRT12
locus tag: YCR045C
gene synonym: OSW3
so part of: sequence
location: complement(<208135..>209610)
location: region:208135-209610:-1
so has part: feature:208135-209610:-1:exon
subclass of: SO_0000010

850412
type: Gene
SIO_000068: ncbigene

position:208135:-1
position: 208135
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:209610:-1
position: 209610
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:208135-209610:-1:exon

YCR045C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: OSW3
gene: RRT12
locus tag: YCR045C
gene synonym: OSW3
product: Rrt12p
transcript id: NM_001178759.1
SIO_010081: YCR045C
subclass of: SO_0000673
so part of: YCR045C
location: complement(<208135..>209610)
location: region:208135-209610:-1
so has part: feature:208135-209610:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:208135-209610:-1:exon

YCR045C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: OSW3
gene: RRT12
locus tag: YCR045C
gene synonym: OSW3
experiment: EXISTENCE:direct assay:GO:0005619 ascospore wall [PMID:19779569]
experiment: EXISTENCE:direct assay:GO:0005635 nuclear envelope [PMID:19779569]
experiment: EXISTENCE:mutant phenotype:GO:0030476 ascospore wall assembly [PMID:19779569]
note: Probable subtilisin-family protease; role in formation of the dityrosine layer of spore walls; localizes to the spore wall and also the nuclear envelope and ER region in mature spores
codon start: 1
product: Rrt12p
translation: MKPQCILISLLVNLAYAEEYLVRFKNPTAFQQFTSNSNRSWRQFIDNKIEKKFSIGSFRGVTMNLSKNLVNKLKKSPLVADIVPNFRFEAFEGDSVNSAESSYTFNATAKYSYEDVEEEQNITYQPDAPRHLARISRHYQLPFDVGDKDRYKSWFNYYYEHDYQGQDVNAYIMDTGIFADHPEFEDRVIQGIDLTKEGFGDQNGHGTHVAGLVGSKTYGAAKRVNLVEVKVLGKDGSGEASNVLSGLEFIVEHCTKVSRPQGKKCVANLSLGSFRSPIINMAVEGAIEEGIVFVAAAGNFNLDAYWASPASAENVITVGAFDDHIDTIAKFSNWGPCVNIFAPGVEIESLSHLNYNDTLILSGTSMSTPIVTGVAAILLSKGIEPEMIAQEIEYLSTRNVFHRRTLFFKPSTPNQILYNGVDKLDDPYDDETFPRLNIEAIAKELEEYNATLQTPMSENLQSGSKLWGWNNDVTLPLGEIRLKRRDFMKNL
SIO_010081: YCR045C
subclass of: SO_0000673
so part of: YCR045C
location: complement(208135..209610)
location: region:208135-209610:-1
so has part: feature:208135-209610:-1:exon

NP_009974.1
type: Protein
SIO_000068: ncbiprotein

S000000641
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:208135-209610:-1:exon

YCR046C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: bL19m
gene: IMG1
locus tag: YCR046C
gene synonym: bL19m
so part of: sequence
location: complement(<209914..>210423)
location: region:209914-210423:-1
so has part: feature:209914-210423:-1:exon
subclass of: SO_0000010

850413
type: Gene
SIO_000068: ncbigene

position:209914:-1
position: 209914
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:210423:-1
position: 210423
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:209914-210423:-1:exon

YCR046C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: bL19m
gene: IMG1
locus tag: YCR046C
gene synonym: bL19m
product: mitochondrial 54S ribosomal protein IMG1
transcript id: NM_001178760.1
SIO_010081: YCR046C
subclass of: SO_0000673
so part of: YCR046C
location: complement(<209914..>210423)
location: region:209914-210423:-1
so has part: feature:209914-210423:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:209914-210423:-1:exon

YCR046C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: bL19m
gene: IMG1
locus tag: YCR046C
gene synonym: bL19m
experiment: EXISTENCE:curator inference:GO:0032543 mitochondrial translation [PMID:12392552]
experiment: EXISTENCE:direct assay:GO:0003735 structural constituent of ribosome [PMID:12392552]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005762 mitochondrial large ribosomal subunit [PMID:12392552]
note: Mitochondrial ribosomal protein of the large subunit; required for respiration and for maintenance of the mitochondrial genome
codon start: 1
product: mitochondrial 54S ribosomal protein IMG1
translation: MWSRNVRLLGSWTRSYMVPATKRKTIPVYPPVQRIASSQIMKQVALSEIESLDPGAVKRKLISKKNKDRLKAGDVVRIVYDSSKCSYDTFVGYILSIDRKQLVQDASLLLRNQIAKTAVEIRVPLFSPLIERIDLLTPHVSSRQRNKHYYIRGTRLDVGDLEAGLRRKK
SIO_010081: YCR046C
subclass of: SO_0000673
so part of: YCR046C
location: complement(209914..210423)
location: region:209914-210423:-1
so has part: feature:209914-210423:-1:exon

NP_009975.1
type: Protein
SIO_000068: ncbiprotein

S000000642
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:209914-210423:-1:exon

YCR047C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: BUD23
locus tag: YCR047C
so part of: sequence
location: complement(<210718..>211545)
location: region:210718-211545:-1
so has part: feature:210718-211545:-1:exon
subclass of: SO_0000010

850414
type: Gene
SIO_000068: ncbigene

position:210718:-1
position: 210718
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:211545:-1
position: 211545
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:210718-211545:-1:exon

YCR047C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: BUD23
locus tag: YCR047C
product: 18S rRNA (guanine1575-N7)-methyltransferase
transcript id: NM_001178761.1
SIO_010081: YCR047C
subclass of: SO_0000673
so part of: YCR047C
location: complement(<210718..>211545)
location: region:210718-211545:-1
so has part: feature:210718-211545:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:210718-211545:-1:exon

YCR047C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: BUD23
locus tag: YCR047C
EC number: 2.1.1.309
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:18332120]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0000056 ribosomal small subunit export from nucleus [PMID:18332120]
experiment: EXISTENCE:mutant phenotype:GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:18332120]
experiment: EXISTENCE:mutant phenotype:GO:0016435 rRNA (guanine) methyltransferase activity [PMID:18332120]
experiment: EXISTENCE:mutant phenotype:GO:0070476 rRNA (guanine-N7)-methylation [PMID:18332120]
note: Ribosome biogenesis factor; methyltransferase that methylates residue G1575 of 18S rRNA; required for rRNA processing and nuclear export of 40S ribosomal subunits independently of methylation activity; required for recruitment of Rps2p; functions with DEAH-box RNA helicase Ecm16p; diploid mutant displays random budding pattern; functional homolog of human WBSCR22
codon start: 1
product: 18S rRNA (guanine1575-N7)-methyltransferase
translation: MSRPEELAPPEIFYNDSEAHKYTGSTRVQHIQAKMTLRALELLNLQPCSFILDIGCGSGLSGEILTQEGDHVWCGLDISPSMLATGLSRELEGDLMLQDMGTGIPFRAGSFDAAISISAIQWLCNADTSYNDPKQRLMRFFNTLYAALKKGGKFVAQFYPKNDDQVDDILQSAKVAGFSGGLVVDDPESKKNKKYYLVLSSGAPPQGEEQVNLDGVTMDEENVNLKKQLRQRLKGGKDKESAKSFILRKKELMKRRGRKVAKDSKFTGRKRRHRF
SIO_010081: YCR047C
subclass of: SO_0000673
so part of: YCR047C
location: complement(210718..211545)
location: region:210718-211545:-1
so has part: feature:210718-211545:-1:exon

NP_009976.1
type: Protein
SIO_000068: ncbiprotein

S000000643
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:210718-211545:-1:exon

YCR048W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SAT2
gene: ARE1
locus tag: YCR048W
gene synonym: SAT2
so part of: sequence
location: <211929..>213761
location: region:211929-213761:1
so has part: feature:211929-213761:1:exon
subclass of: SO_0000010

850415
type: Gene
SIO_000068: ncbigene

position:211929:1
position: 211929
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:213761:1
position: 213761
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:211929-213761:1:exon

YCR048W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SAT2
gene: ARE1
locus tag: YCR048W
gene synonym: SAT2
product: sterol acyltransferase
transcript id: NM_001178762.1
SIO_010081: YCR048W
subclass of: SO_0000673
so part of: YCR048W
location: <211929..>213761
location: region:211929-213761:1
so has part: feature:211929-213761:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:211929-213761:1:exon

YCR048W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SAT2
gene: ARE1
locus tag: YCR048W
gene synonym: SAT2
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:10672016|PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0034737 ergosterol O-acyltransferase activity [PMID:10672016]
experiment: EXISTENCE:genetic interaction:GO:0034738 lanosterol O-acyltransferase activity [PMID:10672016]
experiment: EXISTENCE:mutant phenotype:GO:0016125 sterol metabolic process [PMID:10672016]
experiment: EXISTENCE:mutant phenotype:GO:0034738 lanosterol O-acyltransferase activity [PMID:10672016]
note: Acyl-CoA:sterol acyltransferase; endoplasmic reticulum enzyme that contributes the major sterol esterification activity in the absence of oxygen; ARE1 has a paralog, ARE2, that arose from the whole genome duplication
codon start: 1
product: sterol acyltransferase
translation: MTETKDLLQDEEFLKIRRLNSAEANKRHSVTYDNVILPQESMEVSPRSSTTSLVEPVESTEGVESTEAERVAGKQEQEEEYPVDAHMQKYLSHLKSKSRSRFHRKDASKYVSFFGDVSFDPRPTLLDSAINVPFQTTFKGPVLEKQLKNLQLTKTKTKATVKTTVKTTEKTDKADAPPGEKLESNFSGIYVFAWMFLGWIAIRCCTDYYASYGSAWNKLEIVQYMTTDLFTIAMLDLAMFLCTFFVVFVHWLVKKRIINWKWTGFVAVSIFELAFIPVTFPIYVYYFDFNWVTRIFLFLHSVVFVMKSHSFAFYNGYLWDIKQELEYSSKQLQKYKESLSPETREILQKSCDFCLFELNYQTKDNDFPNNISCSNFFMFCLFPVLVYQINYPRTSRIRWRYVLEKVCAIIGTIFLMMVTAQFFMHPVAMRCIQFHNTPTFGGWIPATQEWFHLLFDMIPGFTVLYMLTFYMIWDALLNCVAELTRFADRYFYGDWWNCVSFEEFSRIWNVPVHKFLLRHVYHSSMGALHLSKSQATLFTFFLSAVFHEMAMFAIFRRVRGYLFMFQLSQFVWTALSNTKFLRARPQLSNVVFSFGVCSGPSIIMTLYLTL
SIO_010081: YCR048W
subclass of: SO_0000673
so part of: YCR048W
location: 211929..213761
location: region:211929-213761:1
so has part: feature:211929-213761:1:exon

NP_009978.1
type: Protein
SIO_000068: ncbiprotein

S000000644
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:211929-213761:1:exon

YCR050C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCR050C
so part of: sequence
location: complement(<213464..>213772)
location: region:213464-213772:-1
so has part: feature:213464-213772:-1:exon
subclass of: SO_0000010

850417
type: Gene
SIO_000068: ncbigene

position:213464:-1
position: 213464
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:213772:-1
position: 213772
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:213464-213772:-1:exon

YCR050C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCR050C
product: uncharacterized protein
transcript id: NM_001178764.1
SIO_010081: YCR050C
subclass of: SO_0000673
so part of: YCR050C
location: complement(<213464..>213772)
location: region:213464-213772:-1
so has part: feature:213464-213772:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:213464-213772:-1:exon

YCR050C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YCR050C
note: Non-essential hypothetical protein; deletion mutant is synthetically sick or lethal with alpha-synuclein
codon start: 1
product: uncharacterized protein
translation: MVAVHKVRYNVIMILGPEQTPNEKTTLDNCGLARRNLVLLKAVHTNCDSWNMNRYPLTLLKMANMAISWNTALKKKVNNVAWLLLKCNAPMELWYTCLSKNL
SIO_010081: YCR050C
subclass of: SO_0000673
so part of: YCR050C
location: complement(213464..213772)
location: region:213464-213772:-1
so has part: feature:213464-213772:-1:exon

NP_009979.1
type: Protein
SIO_000068: ncbiprotein

S000000646
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:213464-213772:-1:exon

YCR051W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCR051W
so part of: sequence
location: <214071..>214739
location: region:214071-214739:1
so has part: feature:214071-214739:1:exon
subclass of: SO_0000010

850418
type: Gene
SIO_000068: ncbigene

position:214071:1
position: 214071
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:214739:1
position: 214739
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:214071-214739:1:exon

YCR051W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCR051W
product: uncharacterized protein
transcript id: NM_001178765.1
SIO_010081: YCR051W
subclass of: SO_0000673
so part of: YCR051W
location: <214071..>214739
location: region:214071-214739:1
so has part: feature:214071-214739:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:214071-214739:1:exon

YCR051W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YCR051W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
note: hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; contains ankyrin (Ank) repeats; YCR051W is not an essential gene
codon start: 1
product: uncharacterized protein
translation: MNANIWVAASDGNLDRVEHILRESKGAMTPQSKDINGYTPMHAAAAYGHLDLLKKMCNEYNGDINVLDNDGDTPLHHVEDVATARLIVEELGGDFTIRNVEGQTPYDSFVENGEDGELIEYMRIKSGVADVHGVDGVQGEGVIDSKLLEEFKDNVRYTLENDPEEGADEATLQRRRQLEQIITGDNAEEELERYIRAMVREQMLGQGSMAGSGDEPDSKRRK
SIO_010081: YCR051W
subclass of: SO_0000673
so part of: YCR051W
location: 214071..214739
location: region:214071-214739:1
so has part: feature:214071-214739:1:exon

NP_009980.1
type: Protein
SIO_000068: ncbiprotein

S000000647
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:214071-214739:1:exon

YCR052W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RSC6
locus tag: YCR052W
so part of: sequence
location: <214994..>216445
location: region:214994-216445:1
so has part: feature:214994-216445:1:exon
subclass of: SO_0000010

850419
type: Gene
SIO_000068: ncbigene

position:214994:1
position: 214994
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:216445:1
position: 216445
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:214994-216445:1:exon

YCR052W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RSC6
locus tag: YCR052W
product: Rsc6p
transcript id: NM_001178766.1
SIO_010081: YCR052W
subclass of: SO_0000673
so part of: YCR052W
location: <214994..>216445
location: region:214994-216445:1
so has part: feature:214994-216445:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:214994-216445:1:exon

YCR052W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RSC6
locus tag: YCR052W
experiment: EXISTENCE:direct assay:GO:0005198 structural molecule activity [PMID:31886770]
experiment: EXISTENCE:direct assay:GO:0006337 nucleosome disassembly [PMID:16492771]
experiment: EXISTENCE:direct assay:GO:0006338 chromatin remodeling [PMID:31886770]
experiment: EXISTENCE:direct assay:GO:0016586 RSC-type complex [PMID:10619019|PMID:12183366]
experiment: EXISTENCE:direct assay:GO:0032968 positive regulation of transcription elongation by RNA polymerase II [PMID:17081996]
note: Component of the RSC chromatin remodeling complex; essential for mitotic growth; RSC6 has a paralog, SNF12, that arose from the whole genome duplication
codon start: 1
product: Rsc6p
translation: MVTQTNPVPVTYPTDAYIPTYLPDDKVSNLADLKKLIEMDSRLDLYLTRRRLDTSINLPTNTKTKDHPPNKEMLRIYVYNTTESSPRSDSGTPADSGKTTWTLRIEGKLLHESANGKHPFSEFLEGVAVDFKRLKPLGMGKKRKRDSSLSLPLNLQQPEYNDQDSTMGDNDNGEDEDSAEAESREEIVDALEWNYDENNVVEFDGIDIKRQGKDNLRCSITIQLRGVDGGKVQYSPNLATLIGMQTGSVNDAVYSIYKYILINNLFVTEQTEAQDGSNDAEDSSNENNNKNGAGDDDGVEGSTPKDKPELGEVKLDSLLQKVLDTNAAHLPLMNVVQTVNKLVSPLPPIILDYTIDLSKDTTYGATTLDVDVSHILHQPQPQPNLQKEEETDAEDTAKLREITKLALQLNSSAQKYQFFHELSLHPRETLTHYLWSSKQNELVLQGDQYFNEDAARTSDIYSNNNNDRSLMGNISLLYSQGRL
SIO_010081: YCR052W
subclass of: SO_0000673
so part of: YCR052W
location: 214994..216445
location: region:214994-216445:1
so has part: feature:214994-216445:1:exon

NP_009981.1
type: Protein
SIO_000068: ncbiprotein

S000000648
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:214994-216445:1:exon

YCR053W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: THR4
locus tag: YCR053W
so part of: sequence
location: <216697..>218241
location: region:216697-218241:1
so has part: feature:216697-218241:1:exon
subclass of: SO_0000010

850420
type: Gene
SIO_000068: ncbigene

position:216697:1
position: 216697
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:218241:1
position: 218241
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:216697-218241:1:exon

YCR053W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: THR4
locus tag: YCR053W
product: threonine synthase THR4
transcript id: NM_001178767.1
SIO_010081: YCR053W
subclass of: SO_0000673
so part of: YCR053W
location: <216697..>218241
location: region:216697-218241:1
so has part: feature:216697-218241:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:216697-218241:1:exon

YCR053W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: THR4
locus tag: YCR053W
EC number: 4.2.3.1
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095|PMID:24390141]
experiment: EXISTENCE:mutant phenotype:GO:0004795 threonine synthase activity [PMID:8082795]
experiment: EXISTENCE:mutant phenotype:GO:0009088 threonine biosynthetic process [PMID:8082795]
note: Threonine synthase; conserved protein that catalyzes formation of threonine from O-phosphohomoserine; expression is regulated by the GCN4-mediated general amino acid control pathway
codon start: 1
product: threonine synthase THR4
translation: MPNASQVYRSTRSSSPKTISFEEAIIQGLATDGGLFIPPTIPQVDQATLFNDWSKLSFQDLAFAIMRLYIAQEEIPDADLKDLIKRSYSTFRSDEVTPLVQNVTGDKENLHILELFHGPTYAFKDVALQFVGNLFEYFLQRTNANLPEGEKKQITVVGATSGDTGSAAIYGLRGKKDVSVFILYPTGRISPIQEEQMTTVPDENVQTLSVTGTFDNCQDIVKAIFGDKEFNSKHNVGAVNSINWARILAQMTYYFYSFFQATNGKDSKKVKFVVPSGNFGDILAGYFAKKMGLPIEKLAIATNENDILDRFLKSGLYERSDKVAATLSPAMDILISSNFERLLWYLAREYLANGDDLKAGEIVNNWFQELKTNGKFQVDKSIIEGASKDFTSERVSNEETSETIKKIYESSVNPKHYILDPHTAVGVCATERLIAKDNDKSIQYISLSTAHPAKFADAVNNALSGFSNYSFEKDVLPEELKKLSTLKKKLKFIERADVELVKNAIEEELAKMKL
SIO_010081: YCR053W
subclass of: SO_0000673
so part of: YCR053W
location: 216697..218241
location: region:216697-218241:1
so has part: feature:216697-218241:1:exon

NP_009982.1
type: Protein
SIO_000068: ncbiprotein

S000000649
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:216697-218241:1:exon

YCR054C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CTR86
locus tag: YCR054C
so part of: sequence
location: complement(<218376..>220067)
location: region:218376-220067:-1
so has part: feature:218376-220067:-1:exon
subclass of: SO_0000010

850421
type: Gene
SIO_000068: ncbigene

position:218376:-1
position: 218376
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:220067:-1
position: 220067
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:218376-220067:-1:exon

YCR054C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CTR86
locus tag: YCR054C
product: Ctr86p
transcript id: NM_001178768.1
SIO_010081: YCR054C
subclass of: SO_0000673
so part of: YCR054C
location: complement(<218376..>220067)
location: region:218376-220067:-1
so has part: feature:218376-220067:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:218376-220067:-1:exon

YCR054C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CTR86
locus tag: YCR054C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095|PMID:22842922]
note: Essential hypothetical protein; with orthologs in Ashbya gossypii and Candida albicans; similar to human ATXN10, mutations in which cause spinocerebellar ataxia type 10; codon usage corresponds to that observed for yeast genes expressed at low levels; relative distribution to the nucleus increases upon DNA replication stress
codon start: 1
product: Ctr86p
translation: MPMNNFLDEFNLFDSIITMMKNDPCCVEDYEPIVENLNRIFQRTFNDEEHRKSMANSQLFWERLRDTLEAMLLPASLNENSSIPYTRTVRGLILMMRNLAAENQEIPQKLLLQNLVIRGFLHATSEYVVDTPLIKHLYIACLTCLFNIQQNYSTVDMTTFPALLQFLQYPYGIKLEDGEEEEHFWLPYLFLFKTYLNNDEFSNEFFRDNDTPQKDYYCVRDRIFFDIVTAKFIQDQENSFLIEKGRNYLDDSKLEITSIDLSVLECISKSLTTASFGKYLNGLEERQPGKFTTLLQILQLVVTSKEDWNTYELTAIMSWCYPILQRLACKDIPAFFNKSCNDYAPSVAIQLHSTLLSCLDIISDLCKFNHVRKFLISYDSVKILVSLLDTFQKNLLRINFLKGNGDTVNEIKITDHEGNKIEDRLLIFNRVNTNESFIRADNFPHCKLVIIEILASLVYAHPEIQDQIRELGGLALILSNCVIDDNDPFIKERSIVCLKFLLKNNAKNQEYVKKMEAQDVVQDDALSKAGFEISVEKGGKVRLVSKEEDPGNENSEIISIDED
SIO_010081: YCR054C
subclass of: SO_0000673
so part of: YCR054C
location: complement(218376..220067)
location: region:218376-220067:-1
so has part: feature:218376-220067:-1:exon

NP_009983.1
type: Protein
SIO_000068: ncbiprotein

S000000650
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:218376-220067:-1:exon

YCR057C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: UTP1
alternative label: YCR055C
alternative label: YCR058C
gene: PWP2
locus tag: YCR057C
gene synonym: UTP1; YCR055C; YCR058C
so part of: sequence
location: complement(<220457..>223228)
location: region:220457-223228:-1
so has part: feature:220457-223228:-1:exon
subclass of: SO_0000010

850422
type: Gene
SIO_000068: ncbigene

position:220457:-1
position: 220457
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:223228:-1
position: 223228
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:220457-223228:-1:exon

YCR057C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: UTP1
alternative label: YCR055C
alternative label: YCR058C
gene: PWP2
locus tag: YCR057C
gene synonym: UTP1; YCR055C; YCR058C
product: snoRNA-binding rRNA-processing protein PWP2
transcript id: NM_001178769.1
SIO_010081: YCR057C
subclass of: SO_0000673
so part of: YCR057C
location: complement(<220457..>223228)
location: region:220457-223228:-1
so has part: feature:220457-223228:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:220457-223228:-1:exon

YCR057C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: UTP1
alternative label: YCR055C
alternative label: YCR058C
gene: PWP2
locus tag: YCR057C
gene synonym: UTP1; YCR055C; YCR058C
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:12068309|PMID:12150911]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:8804409]
experiment: EXISTENCE:direct assay:GO:0030686 90S preribosome [PMID:15231838|PMID:12150911]
experiment: EXISTENCE:direct assay:GO:0032040 small-subunit processome [PMID:12068309]
experiment: EXISTENCE:direct assay:GO:0034388 Pwp2p-containing subcomplex of 90S preribosome [PMID:15231838|PMID:17515605]
experiment: EXISTENCE:mutant phenotype:GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:15231838|PMID:15489292|PMID:15590835]
experiment: EXISTENCE:mutant phenotype:GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:12068309]
experiment: EXISTENCE:mutant phenotype:GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:15231838|PMID:15489292|PMID:15590835]
experiment: EXISTENCE:mutant phenotype:GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:15489292|PMID:15590835|PMID:15231838]
experiment: EXISTENCE:mutant phenotype:GO:0000920 septum digestion after cytokinesis [PMID:8804409]
experiment: EXISTENCE:mutant phenotype:GO:0030010 establishment of cell polarity [PMID:8804409]
note: Conserved 90S pre-ribosomal component; essential for proper endonucleolytic cleavage of the 35 S rRNA precursor at A0, A1, and A2 sites; contains eight WD-repeats; PWP2 deletion leads to defects in cell cycle and bud morphogenesis
codon start: 1
product: snoRNA-binding rRNA-processing protein PWP2
translation: MKSDFKFSNLLGTVYRQGNITFSDDGKQLLSPVGNRVSVFDLINNKSFTFEYEHRKNIAAIDLNKQGTLLISIDEDGRAILVNFKARNVLHHFNFKEKCSAVKFSPDGRLFALASGRFLQIWKTPDVNKDRQFAPFVRHRVHAGHFQDITSLTWSQDSRFILTTSKDLSAKIWSVDSEEKNLAATTFNGHRDYVMGAFFSHDQEKIYTVSKDGAVFVWEFTKRPSDDDDNESEDDDKQEEVDISKYSWRITKKHFFYANQAKVKCVTFHPATRLLAVGFTSGEFRLYDLPDFTLIQQLSMGQNPVNTVSVNQTGEWLAFGSSKLGQLLVYEWQSESYILKQQGHFDSTNSLAYSPDGSRVVTASEDGKIKVWDITSGFCLATFEEHTSSVTAVQFAKRGQVMFSSSLDGTVRAWDLIRYRNFRTFTGTERIQFNCLAVDPSGEVVCAGSLDNFDIHVWSVQTGQLLDALSGHEGPVSCLSFSQENSVLASASWDKTIRIWSIFGRSQQVEPIEVYSDVLALSMRPDGKEVAVSTLKGQISIFNIEDAKQVGNIDCRKDIISGRFNQDRFTAKNSERSKFFTTIHYSFDGMAIVAGGNNNSICLYDVPNEVLLKRFIVSRNMALNGTLEFLNSKKMTEAGSLDLIDDAGENSDLEDRIDNSLPGSQRGGDLSTRKMRPEVRVTSVQFSPTANAFAAASTEGLLIYSTNDTILFDPFDLDVDVTPHSTVEALREKQFLNALVMAFRLNEEYLINKVYEAIPIKEIPLVASNIPAIYLPRILKFIGDFAIESQHIEFNLIWIKALLSASGGYINEHKYLFSTAMRSIQRFIVRVAKEVVNTTTDNKYTYRFLVSTDGSMEDGAADDDEVLLKDDADEDNEENEENDVVMESDDEEGWIGFNGKDNKLPLSNENDSSDEEENEKELP
SIO_010081: YCR057C
subclass of: SO_0000673
so part of: YCR057C
location: complement(220457..223228)
location: region:220457-223228:-1
so has part: feature:220457-223228:-1:exon

NP_009984.1
type: Protein
SIO_000068: ncbiprotein

S000000653
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:220457-223228:-1:exon

YCR059C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: YIH1
locus tag: YCR059C
so part of: sequence
location: complement(<223454..>224230)
location: region:223454-224230:-1
so has part: feature:223454-224230:-1:exon
subclass of: SO_0000010

850423
type: Gene
SIO_000068: ncbigene

position:223454:-1
position: 223454
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:224230:-1
position: 224230
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:223454-224230:-1:exon

YCR059C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: YIH1
locus tag: YCR059C
product: Yih1p
transcript id: NM_001178770.1
SIO_010081: YCR059C
subclass of: SO_0000673
so part of: YCR059C
location: complement(<223454..>224230)
location: region:223454-224230:-1
so has part: feature:223454-224230:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:223454-224230:-1:exon

YCR059C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: YIH1
locus tag: YCR059C
experiment: EXISTENCE:direct assay:GO:0003785 actin monomer binding [PMID:15126500]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0043022 ribosome binding [PMID:22404850]
experiment: EXISTENCE:direct assay:GO:1905538 polysome binding [PMID:22404850]
experiment: EXISTENCE:mutant phenotype:GO:0001933 negative regulation of protein phosphorylation [PMID:15126500]
experiment: EXISTENCE:mutant phenotype:GO:0004860 protein kinase inhibitor activity [PMID:15126500]
note: Negative regulator of eIF2 kinase Gcn2p; competes with Gcn2p for binding to Gcn1p; may contribute to regulation of translation in response to starvation via regulation of Gcn2p; binds to monomeric actin and to ribosomes and polyribosomes; ortholog of mammalian IMPACT
codon start: 1
product: Yih1p
translation: MDDDHEQLVEELEAVEAIYPDLLSKKQEDGSIIVVKVPQHEYMTLQISFPTHYPSEEAPNVIEVGVCTSLAKRDLYDTKYLQHLFQEVMDSVFHRGSVCLFDFLTELDGVLYVEPEEETEPVQQSDIPTDPFEGWTASDPITDRGSTFMAFAAHVTSEEQAFAMLDLLKTDSKMRKANHVMSAWRIKQDGSAATYQDSDDDGETAAGSRMLHLITIMDVWNVIVVVARWFGGAHIGPDRFKHINSTAREAVVRAGFDS
SIO_010081: YCR059C
subclass of: SO_0000673
so part of: YCR059C
location: complement(223454..224230)
location: region:223454-224230:-1
so has part: feature:223454-224230:-1:exon

NP_009985.1
type: Protein
SIO_000068: ncbiprotein

S000000655
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:223454-224230:-1:exon

YCR060W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TAH1
locus tag: YCR060W
so part of: sequence
location: <224399..>224734
location: region:224399-224734:1
so has part: feature:224399-224734:1:exon
subclass of: SO_0000010

850424
type: Gene
SIO_000068: ncbigene

position:224399:1
position: 224399
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:224734:1
position: 224734
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:224399-224734:1:exon

YCR060W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TAH1
locus tag: YCR060W
product: Tah1p
transcript id: NM_001178771.1
SIO_010081: YCR060W
subclass of: SO_0000673
so part of: YCR060W
location: <224399..>224734
location: region:224399-224734:1
so has part: feature:224399-224734:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:224399-224734:1:exon

YCR060W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TAH1
locus tag: YCR060W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0051087 chaperone binding [PMID:18412542]
experiment: EXISTENCE:direct assay:GO:0097255 R2TP complex [PMID:15766533]
experiment: EXISTENCE:genetic interaction:GO:0006457 protein folding [PMID:15766533]
experiment: EXISTENCE:mutant phenotype:GO:0000492 box C/D snoRNP assembly [PMID:18268103]
experiment: EXISTENCE:mutant phenotype:GO:0006457 protein folding [PMID:15766533]
experiment: EXISTENCE:mutant phenotype:GO:0051087 chaperone binding [PMID:15766533]
experiment: EXISTENCE:physical interaction:GO:0006457 protein folding [PMID:15766533]
experiment: EXISTENCE:physical interaction:GO:0051087 chaperone binding [PMID:15766533]
experiment: EXISTENCE:physical interaction:GO:0097255 R2TP complex [PMID:18268103]
note: Component of conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1); R2TP complex interacts with Hsp90 (Hsp82p and Hsc82p) to mediate assembly of large protein complexes such as box C/D snoRNPs and RNA polymerase II; contains a single TPR domain with at least two TPR motifs; plays a role in determining prion variants
codon start: 1
product: Tah1p
translation: MSQFEKQKEQGNSLFKQGLYREAVHCYDQLITAQPQNPVGYSNKAMALIKLGEYTQAIQMCQQGLRYTSTAEHVAIRSKLQYRLELAQGAVGSVQIPVVEVDELPEGYDRS
SIO_010081: YCR060W
subclass of: SO_0000673
so part of: YCR060W
location: 224399..224734
location: region:224399-224734:1
so has part: feature:224399-224734:1:exon

NP_009986.1
type: Protein
SIO_000068: ncbiprotein

S000000656
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:224399-224734:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS315; Highly-active autonomously replicating sequence; initiates replication in 90% of cell cycles
so part of: sequence
location: 224816..225061
location: region:224816-225061:1
so has part: feature:224816-225061:1:region

S000028490
type: SGD
SIO_000068: sgd

position:224816:1
position: 224816
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:225061:1
position: 225061
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:224816-225061:1:region

YCR061W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YCR062W
gene: TVS1
locus tag: YCR061W
gene synonym: YCR062W
so part of: sequence
location: <225563..>227458
location: region:225563-227458:1
so has part: feature:225563-227458:1:exon
subclass of: SO_0000010

850425
type: Gene
SIO_000068: ncbigene

position:225563:1
position: 225563
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:227458:1
position: 227458
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:225563-227458:1:exon

YCR061W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YCR062W
gene: TVS1
locus tag: YCR061W
gene synonym: YCR062W
product: Tvs1p
transcript id: NM_001178772.1
SIO_010081: YCR061W
subclass of: SO_0000673
so part of: YCR061W
location: <225563..>227458
location: region:225563-227458:1
so has part: feature:225563-227458:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:225563-227458:1:exon

YCR061W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YCR062W
gene: TVS1
locus tag: YCR061W
gene synonym: YCR062W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0008361 regulation of cell size [PMID:12089449]
note: hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; non-essential gene; upregulated by and required for tolerance to 4-Methylcyclohexane methanol; induced by treatment with 8-methoxypsoralen and UVA irradiation; contains 10-11 predicted transmembrane domains
codon start: 1
product: Tvs1p
translation: MVRFVSILSLFGCAATLVTAHDDMDMDMDMDMDMDMNIDTTTSQSIDVSSTASIVPVPHEPKHLHGLPILQSPSLTPAERLYWENYNTTTYFTTQAGNRSALRYHIITLLLVAFVLYPVSLALSAARSRWYLPLLFVNLCICISSVMALSVFKNTFPEEDWYAHNIYGTTSVLLLVFMLVHFFAAVLSVPVSLASKKEYRPVDTIPLNDLESTPVMVNSARGSPSPSSNRDTLFSLSSDTTTATATNNNKRRRAEGEDEGDNTSNHDTLRDEDYDNDDDEIASIEAPPLLPQDIPVFRILFTNTKYQMLAAHLSCVANVVFHMLTYPLFMYIFVDLIIGFAVGNLLGKGIRIFNLLAHWIKGGVFFTLGVVSLARYCGFAAKYGWAWNNISFTSQLTQTRSSNLLFRFAPAGTFTMEFVESFLIFFYGSTNIFLEHLAGNGGAWTAKDLQHVSIAFMFIGTGLCGLLTEYKLNHWRFEHARKRPQTDVVAATPGYSPNPFPAFTIFWTGILMSQHAQSSQFSTTIHTQWGYLLSYGSFFRLLTFLILFLVPNTNSAASKPFTELITSFCLLCGGLVFMESTDQSIEAMEYRGFTPMFTFNLSVGFVSLLMAWEMILFIWKDWLIKTRKTSL
SIO_010081: YCR061W
subclass of: SO_0000673
so part of: YCR061W
location: 225563..227458
location: region:225563-227458:1
so has part: feature:225563-227458:1:exon

NP_009987.2
type: Protein
SIO_000068: ncbiprotein

S000000657
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:225563-227458:1:exon

YNCC0013W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SUP61
locus tag: YNCC0013W
so part of: sequence
location: 227942..228042
location: region:227942-228042:1
so has part: feature:227942-228042:1:exon
subclass of: SO_0000663

850426
type: Gene
SIO_000068: ncbigene

position:227942:1
position: 227942
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:228042:1
position: 228042
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:227942-228042:1:exon

YNCC0013W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
gene: SUP61
locus tag: YNCC0013W
product: tRNA-Ser
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Serine tRNA (tRNA-Ser), predicted by tRNAscan-SE analysis; i6A37 modification is catalyzed by Mod5p; can mutate to suppress amber or ochre nonsense mutations; suppressor mutant alleles are recessive lethal and can only be maintained when an additional wild-type copy of the gene is present, because SUP61 encodes the only tRNA species that can decode UCG codons
SIO_010081: YNCC0013W
subclass of: SO_0000673
so part of: YNCC0013W
location: join(227942..227978,227998..228042)
location: region:227942-228042:1
so has part: feature:227942-227978:1:exon
so has part: feature:227998-228042:1:exon

S000006730
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:227942-227978:1:exon

position:227978:1
position: 227978
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:227998-228042:1:exon

position:227998:1
position: 227998
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YCR063W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CWC14
gene: BUD31
locus tag: YCR063W
gene synonym: CWC14
so part of: sequence
location: <228318..>228791
location: region:228318-228791:1
so has part: feature:228318-228791:1:exon
subclass of: SO_0000010

850427
type: Gene
SIO_000068: ncbigene

position:228318:1
position: 228318
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:228791:1
position: 228791
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:228318-228791:1:exon

YCR063W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CWC14
gene: BUD31
locus tag: YCR063W
gene synonym: CWC14
product: U2 snRNP complex subunit BUD31
transcript id: NM_001178774.1
SIO_010081: YCR063W
subclass of: SO_0000673
so part of: YCR063W
location: <228318..>228791
location: region:228318-228791:1
so has part: feature:228318-228791:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:228318-228791:1:exon

YCR063W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CWC14
gene: BUD31
locus tag: YCR063W
gene synonym: CWC14
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005686 U2 snRNP [PMID:16314500]
experiment: EXISTENCE:mutant phenotype:GO:0000282 cellular bud site selection [PMID:11452010]
experiment: EXISTENCE:physical interaction:GO:0000398 mRNA splicing, via spliceosome [PMID:16314500|PMID:15303280]
note: Component of the SF3b subcomplex of the U2 snRNP; increases efficiency of first and second step pre-mRNA splicing; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern; facilitates passage through G1/S Start, but is not required for G2/M transition or exit from mitosis
codon start: 1
product: U2 snRNP complex subunit BUD31
translation: MPRIKTRRSKPAPDGFEKIKPTLTDFEIQLRDAQKDKSSKLAAKSNEQLWEIMQLHHQRSRYIYTLYYKRKAISKDLYDWLIKEKYADKLLIAKWRKTGYEKLCCLRCIQKNETNNGSTCICRVPRAQLEEEARKKGTQVSFHQCVHCGCRGCASTD
SIO_010081: YCR063W
subclass of: SO_0000673
so part of: YCR063W
location: 228318..228791
location: region:228318-228791:1
so has part: feature:228318-228791:1:exon

NP_009990.1
type: Protein
SIO_000068: ncbiprotein

S000000659
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:228318-228791:1:exon

YCR065W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HCM1
locus tag: YCR065W
so part of: sequence
location: <229310..>231004
location: region:229310-231004:1
so has part: feature:229310-231004:1:exon
subclass of: SO_0000010

850429
type: Gene
SIO_000068: ncbigene

position:229310:1
position: 229310
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:231004:1
position: 231004
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:229310-231004:1:exon

YCR065W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HCM1
locus tag: YCR065W
product: Hcm1p
transcript id: NM_001178776.1
SIO_010081: YCR065W
subclass of: SO_0000673
so part of: YCR065W
location: <229310..>231004
location: region:229310-231004:1
so has part: feature:229310-231004:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:229310-231004:1:exon

YCR065W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: HCM1
locus tag: YCR065W
experiment: EXISTENCE:direct assay:GO:0000785 chromatin [PMID:12464632]
experiment: EXISTENCE:direct assay:GO:0003700 DNA-binding transcription factor activity [PMID:16912276]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:19159085|PMID:20847055]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:20847055]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:33339134]
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:19111667]
experiment: EXISTENCE:direct assay:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:8441413]
experiment: EXISTENCE:genetic interaction:GO:0051300 spindle pole body organization [PMID:9920414]
experiment: EXISTENCE:mutant phenotype:GO:0003700 DNA-binding transcription factor activity [PMID:16912276]
experiment: EXISTENCE:mutant phenotype:GO:0007005 mitochondrion organization [PMID:20847055]
experiment: EXISTENCE:mutant phenotype:GO:0034246 mitochondrial transcription factor activity [PMID:33339134]
experiment: EXISTENCE:mutant phenotype:GO:0034599 cellular response to oxidative stress [PMID:20847055]
experiment: EXISTENCE:mutant phenotype:GO:1903108 regulation of mitochondrial transcription [PMID:33339134]
note: Forkhead transcription factor; drives S-phase activation of genes involved in chromosome segregation, spindle dynamics, budding; also activates genes involved in respiration, use of alternative energy sources, NAD synthesis, oxidative stress resistance; regulated by cell wall integrity checkpoint; key factor in early adaptation to nutrient deficiency and diauxic shift; suppressor of calmodulin mutants with specific SPB assembly defects; ortholog of C. elegans lifespan regulator PHA-4
codon start: 1
product: Hcm1p
translation: MMNEDISIIDGHNSFLTEKSTVLLTQAKRTLEDEKEMITPPSSTVRKTMKEVNKRPSHPLSPDHSSPIAPSKAKRQRSDTCARSNGNLTLEEILQSLERRRINGELAKKPPYSYATLICLAILQSQEGKLTLSQIYHWIHVHFPYYKQKDASWQNSIRHNLSLNDAFIKTEKSCDGKGHFWEVRPGAETKFFKGENRGYEFVKDSLQDIGKYFEIDSTLDELEQVESGEGNDDLPDEEEREEAGKFPSIEIQLNSSPILRVSQLHHIPQLKTDNSVLNPHENLESMRNMIENDVNNIDSLEPPYVMKKYHTSLGLPSLVNAKDHFQAGVKNNNITQANRFNTLPITSAKSPQNFRKYFTSFNSNFEDLSPLRSNVGAGSLLDPLPYSPLKLYDQKNLALMSKPQSQQSYSNSQLPPPPSSHGSDLLKTPKMRHSDGLEKTPSRLISTPKDGNSILRKWQTPSHLFEDLYCSPLFRAIETPIRYITTPGGTLETQISPRKSSAPDVLTSATNSKFASSGLFGVDVYSVWKRATEKISDGNNTTDSNQKHHPYHNHPSNDSGNEKN
SIO_010081: YCR065W
subclass of: SO_0000673
so part of: YCR065W
location: 229310..231004
location: region:229310-231004:1
so has part: feature:229310-231004:1:exon

NP_009991.2
type: Protein
SIO_000068: ncbiprotein

S000000661
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:229310-231004:1:exon

YCR066W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RAD18
locus tag: YCR066W
so part of: sequence
location: <231500..>232963
location: region:231500-232963:1
so has part: feature:231500-232963:1:exon
subclass of: SO_0000010

850430
type: Gene
SIO_000068: ncbigene

position:231500:1
position: 231500
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:232963:1
position: 232963
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:231500-232963:1:exon

YCR066W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RAD18
locus tag: YCR066W
product: E3 ubiquitin-protein ligase RAD18
transcript id: NM_001178777.1
SIO_010081: YCR066W
subclass of: SO_0000673
so part of: YCR066W
location: <231500..>232963
location: region:231500-232963:1
so has part: feature:231500-232963:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:231500-232963:1:exon

YCR066W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RAD18
locus tag: YCR066W
EC number: 2.3.2.27
experiment: EXISTENCE:direct assay:GO:0000785 chromatin [PMID:10880451]
experiment: EXISTENCE:direct assay:GO:0003697 single-stranded DNA binding [PMID:7926769|PMID:9287349]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:10880451]
experiment: EXISTENCE:direct assay:GO:0017116 single-stranded DNA helicase activity [PMID:9287349]
experiment: EXISTENCE:direct assay:GO:0097505 Rad6-Rad18 complex [PMID:9287349]
experiment: EXISTENCE:genetic interaction:GO:0042275 error-free postreplication DNA repair [PMID:10924462|PMID:9576943]
experiment: EXISTENCE:genetic interaction:GO:0042276 error-prone translesion synthesis [PMID:11973297|PMID:15687278]
experiment: EXISTENCE:genetic interaction:GO:0070987 error-free translesion synthesis [PMID:9409821]
experiment: EXISTENCE:mutant phenotype:GO:0006513 protein monoubiquitination [PMID:12226657]
note: E3 ubiquitin ligase; forms heterodimer with Rad6p to monoubiquitinate PCNA-K164; heterodimer binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; required for postreplication repair; SUMO-targeted ubiquitin ligase (STUbl) that contains a SUMO-interacting motif (SIM) which stimulates its ubiquitin ligase activity towards the sumoylated form of PCNA
codon start: 1
product: E3 ubiquitin-protein ligase RAD18
translation: MDHQITTASDFTTTSIPSLYQLDTLLRCHICKDFLKVPVLTPCGHTFCSLCIRTHLNNQPNCPLCLFEFRESLLRSEFLVSEIIQSYTSLRSSLLDALRIPKPTPVPENEEVPGPENSSWIELISESESDSVNAADDDLQIVATSERKLAKRSMTDILPLSSKPSKRNFAMFRSERIKKKSKPNEQMAQCPICQQFYPLKALEKTHLDECLTLQSLGKKPKISTTFPTESNPHNKSSSRFKVRTPEVDKSSCGETSHVDKYLNSMMSAEHQRLPKINFTSMTQSQIKQKLSSLGLSTNGTRQNMIKRYNHYEMLWNSNFCDSLEPVDEAELKRQLLSWDVSHNKTPQNSSNKGGISKLMIMKSNGKSSSYRKLLENFKNDKFNRKGWMVMFRKDFARLIREAKMKIKTGSSDSSGSVGHSNDGDGVEKVQSDQGTEDQQMEKDQDTVINEDRVAGERNLPNEDSTDADLSRELMDLNEYSKDPPGNN
SIO_010081: YCR066W
subclass of: SO_0000673
so part of: YCR066W
location: 231500..232963
location: region:231500-232963:1
so has part: feature:231500-232963:1:exon

NP_009992.1
type: Protein
SIO_000068: ncbiprotein

S000000662
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:231500-232963:1:exon

YCR067C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SED4
locus tag: YCR067C
so part of: sequence
location: complement(<233125..>236322)
location: region:233125-236322:-1
so has part: feature:233125-236322:-1:exon
subclass of: SO_0000010

850431
type: Gene
SIO_000068: ncbigene

position:233125:-1
position: 233125
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:236322:-1
position: 236322
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:233125-236322:-1:exon

YCR067C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SED4
locus tag: YCR067C
product: GTPase-activating protein SED4
transcript id: NM_001178778.1
SIO_010081: YCR067C
subclass of: SO_0000673
so part of: YCR067C
location: complement(<233125..>236322)
location: region:233125-236322:-1
so has part: feature:233125-236322:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:233125-236322:-1:exon

YCR067C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SED4
locus tag: YCR067C
experiment: EXISTENCE:direct assay:GO:0003400 regulation of COPII vesicle coating [PMID:21291503]
experiment: EXISTENCE:direct assay:GO:0005096 GTPase activator activity [PMID:21291503]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:24390141]
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:7593162]
experiment: EXISTENCE:direct assay:GO:0043547 positive regulation of GTPase activity [PMID:21291503]
experiment: EXISTENCE:physical interaction:GO:0043547 positive regulation of GTPase activity [PMID:21291503]
note: Integral ER membrane protein that stimulates Sar1p GTPase activity; involved in COPII vesicle budding through disassociation of coat proteins from membranes onto liposomes; binds Sec16p; SED4 has a paralog, SEC12, that arose from the whole genome duplication
codon start: 1
product: GTPase-activating protein SED4
translation: MSGNSANYDVGYPIYGAKFINEGTLLVAGGGGQFNSSFPNKITALKVNFQKKKHIRRFREITLDSIDDAPTSLDCNNNLILVGCNELFNDSSMENVNHHLRKFVFEQEHLKFVASIDFNRTTDPSVFTKFVYINQRATVAAIASSEVPTVIRIIDPRNLTENYEIETGREVNDLHFAPNGILLSYITSNSLEVASVRDGNFVARKTDFDKNLVLSNIRFLNDNTLLVAASLSNSDGVSLLKLGVSSKGVKILKTASFMFDLNGITSMDVSPNKKFVALSSNDNLVAIVSVEKLKLVQLVPRVHESTITKVTFSPDSRYLASTSMGNTINVLKLSGTSSSILRNIWKFFLNFVLLVVLAGAIQLGYKHNVHGFIYKHAHDIYKSKFKENTTIDQGSSSYFTINDDYRGITESADIISATDVASDIETEFSSFDTSTMRTTTEDEQKFVWISSSADSQFTSADIPTSASSSSSSSSSSFYEESVTNEPIVSSPTSEITKPLASPTEPNIVEKPSLPLNSESIDLLSSSSNSITEYPEPTPDLEEKLSSLIVEQSESEITTDRESVSKLLSTESPSLSHMPSSSSSSLSLSSSLTTSPTTALSTSTATAVTTTQTNPTNDAANTSFLDNSKPASTREIYKTKIITEVITKIEYRNIPASDSNAEAEQYVTTSSSMLLTPTDTMVSSPVSEIDPIASELERMVETPTHSISIASEFDSVASNLIPNEEILSTSASQDSISSHPSTFSDSSITSGFQSIEVSTVTSSVLASESIPSISDSTFSKFHSISEPVSSAIVETATSSFSKTETKTSRVIAFSTEDSERSSALIDNSEYTSVLADNLEPTSVLADNSEPTSVLADSSEPTSVFTDAVQSPKTSVGQSSLSESTNIEGTSMASMIFSSSGASIGALSDIGKGTLSVESASSTVAQPMPGVTTTAPSFVSSPHKISASSIDASGFVQKEIMIEVQSSKDSSEAFGVRHKISENVNTPVSRMLTTEMQASGTVDVTEDVSLSSEVISALNVEITSLPNPVAPPQTIAAPLNNNSNTNIVNDDNAVAGTVNYAGLHDEL
SIO_010081: YCR067C
subclass of: SO_0000673
so part of: YCR067C
location: complement(233125..236322)
location: region:233125-236322:-1
so has part: feature:233125-236322:-1:exon

NP_009993.1
type: Protein
SIO_000068: ncbiprotein

S000000663
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:233125-236322:-1:exon

YCR068W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: AUT5
alternative label: CVT17
gene: ATG15
locus tag: YCR068W
gene synonym: AUT5; CVT17
so part of: sequence
location: <237214..>238776
location: region:237214-238776:1
so has part: feature:237214-238776:1:exon
subclass of: SO_0000010

850432
type: Gene
SIO_000068: ncbigene

position:237214:1
position: 237214
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:238776:1
position: 238776
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:237214-238776:1:exon

YCR068W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: AUT5
alternative label: CVT17
gene: ATG15
locus tag: YCR068W
gene synonym: AUT5; CVT17
product: triglyceride lipase ATG15
transcript id: NM_001178779.1
SIO_010081: YCR068W
subclass of: SO_0000673
so part of: YCR068W
location: <237214..>238776
location: region:237214-238776:1
so has part: feature:237214-238776:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:237214-238776:1:exon

YCR068W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: AUT5
alternative label: CVT17
gene: ATG15
locus tag: YCR068W
gene synonym: AUT5; CVT17
EC number: 3.1.1.3
experiment: EXISTENCE:direct assay:GO:0004620 phospholipase activity [PMID:27543826]
experiment: EXISTENCE:direct assay:GO:0005775 vacuolar lumen [PMID:11566994]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0006624 vacuolar protein processing [PMID:11085977]
experiment: EXISTENCE:direct assay:GO:0006660 phosphatidylserine catabolic process [PMID:27543826]
experiment: EXISTENCE:direct assay:GO:0006914 autophagy [PMID:11085977|PMID:11566994]
experiment: EXISTENCE:direct assay:GO:0016020 membrane [PMID:11085977]
experiment: EXISTENCE:direct assay:GO:0030397 membrane disassembly [PMID:11085977]
experiment: EXISTENCE:mutant phenotype:GO:0000425 pexophagy [PMID:31332264]
experiment: EXISTENCE:mutant phenotype:GO:0004620 phospholipase activity [PMID:27543826]
experiment: EXISTENCE:mutant phenotype:GO:0006624 vacuolar protein processing [PMID:11085977]
experiment: EXISTENCE:mutant phenotype:GO:0006660 phosphatidylserine catabolic process [PMID:27543826]
experiment: EXISTENCE:mutant phenotype:GO:0006914 autophagy [PMID:11085977|PMID:11566994]
experiment: EXISTENCE:mutant phenotype:GO:0030397 membrane disassembly [PMID:11085977]
experiment: EXISTENCE:mutant phenotype:GO:0034496 multivesicular body membrane disassembly [PMID:12499386]
experiment: EXISTENCE:mutant phenotype:GO:0034727 piecemeal microautophagy of the nucleus [PMID:18701704]
experiment: EXISTENCE:mutant phenotype:GO:0046461 neutral lipid catabolic process [PMID:26061644]
note: Phospholipase; preferentially hydrolyses phosphatidylserine, with minor activity against cardiolipin and phosphatidylethanolamine; required for lysis of autophagic and CVT bodies; targeted to vacuole via Vps10p-dependent endosomal vacuolar protein sorting pathway; targeted to intravacuolar vesicles during autophagy via multivesicular body (MVB) pathway; required for maintenance of lipid droplet quantity after diauxic shift; regulates lipolysis; expression regulated by Yap1p during autophagy
codon start: 1
product: triglyceride lipase ATG15
translation: MLHKSPSRKRFASPLHLGCILTLTVLCLIAYYFALPDYLSVGKSSSRGAMDQKSDGTFRLKSIYRHGVGANHRLHQRLEVTPEVISAAGMLYQETTTQGQDFEDQEPLWTTNAEYATTNPFDFEFELRRMPLLMKRMKERDPEFIESYIYGETYMTEEEEHAMWIDDDIVAPNITDRGTVVSLALMSSNAYVRIPQTGDWRNVTEPWNETEPEDFGWDGDGIRGHVFYNEVENIVVLSIKGTSAQGLPGSGEDETTGNDKINDNLLFSCCCARVSYLWTTVCDCYVKSYICDESCLEKELRRKDRFYSAVVDIYKGVLKEYPDAAIWVTGHSLGGALASLLGRTFGLPAVAFESPGELLPSKRLHLPFPPGLPSYMEGIWHFGHNADPIFMGTCNGASSSCSLVGYAMETACHTGRVCVYDVVNDKGWSVNMFNHRIHKVIDEVLLGYEQAAKCVEPEPCVDCYNWKFIPSRDWESSSRLITKTKSHAAPTTTTRTTATTTSSSTCVGRNWLGFCTKYEL
SIO_010081: YCR068W
subclass of: SO_0000673
so part of: YCR068W
location: 237214..238776
location: region:237214-238776:1
so has part: feature:237214-238776:1:exon

NP_009994.2
type: Protein
SIO_000068: ncbiprotein

S000000664
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:237214-238776:1:exon

YCR069W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CYP4
alternative label: SCC3
alternative label: YCR070W
gene: CPR4
locus tag: YCR069W
gene synonym: CYP4; SCC3; YCR070W
so part of: sequence
location: <239055..>240011
location: region:239055-240011:1
so has part: feature:239055-240011:1:exon
subclass of: SO_0000010

850433
type: Gene
SIO_000068: ncbigene

position:239055:1
position: 239055
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:240011:1
position: 240011
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:239055-240011:1:exon

YCR069W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CYP4
alternative label: SCC3
alternative label: YCR070W
gene: CPR4
locus tag: YCR069W
gene synonym: CYP4; SCC3; YCR070W
product: peptidylprolyl isomerase family protein CPR4
transcript id: NM_001178780.1
SIO_010081: YCR069W
subclass of: SO_0000673
so part of: YCR069W
location: <239055..>240011
location: region:239055-240011:1
so has part: feature:239055-240011:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:239055-240011:1:exon

YCR069W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CYP4
alternative label: SCC3
alternative label: YCR070W
gene: CPR4
locus tag: YCR069W
gene synonym: CYP4; SCC3; YCR070W
EC number: 5.2.1.8
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
note: Peptidyl-prolyl cis-trans isomerase (cyclophilin); catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; has a potential role in the secretory pathway; CPR4 has a paralog, CPR8, that arose from the whole genome duplication
codon start: 1
product: peptidylprolyl isomerase family protein CPR4
translation: MWLKSLLLCLYSLVLCQVHAAPSSGKQITSKDVDLQKKYEPSPPATHRGIITIEYFDPVSKSMKEADLTFELYGTVVPKTVNNFAMLAHGVKAVIEGKDPNDIHTYSYRKTKINKVYPNKYIQGGVVAPDVGPFTVYGPKFDDENFYLKHDRPERLAMAYFGPDSNTSEFIITTKADGNEELDGKSVVFGQITSGLDQLMDAIQYTETDEYGKPQHELRFLYFVLEILKISNILDLHAAYTEKVEKFRNGDVSVGSTLENIFRNDKAYTPLTTSTGTTAYDLNHPISRALMCLTVLGLCFIAYKGMHEKPHTVSLRHK
SIO_010081: YCR069W
subclass of: SO_0000673
so part of: YCR069W
location: 239055..240011
location: region:239055-240011:1
so has part: feature:239055-240011:1:exon

NP_009995.1
type: Protein
SIO_000068: ncbiprotein

S000000665
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:239055-240011:1:exon

YCR071C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: mL49
gene: IMG2
locus tag: YCR071C
gene synonym: mL49
so part of: sequence
location: complement(<240103..>240543)
location: region:240103-240543:-1
so has part: feature:240103-240543:-1:exon
subclass of: SO_0000010

850434
type: Gene
SIO_000068: ncbigene

position:240103:-1
position: 240103
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:240543:-1
position: 240543
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:240103-240543:-1:exon

YCR071C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: mL49
gene: IMG2
locus tag: YCR071C
gene synonym: mL49
product: mitochondrial 54S ribosomal protein IMG2
transcript id: NM_001178781.1
SIO_010081: YCR071C
subclass of: SO_0000673
so part of: YCR071C
location: complement(<240103..>240543)
location: region:240103-240543:-1
so has part: feature:240103-240543:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:240103-240543:-1:exon

YCR071C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: mL49
gene: IMG2
locus tag: YCR071C
gene synonym: mL49
experiment: EXISTENCE:curator inference:GO:0032543 mitochondrial translation [PMID:12392552]
experiment: EXISTENCE:direct assay:GO:0003735 structural constituent of ribosome [PMID:12392552]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:24769239|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005762 mitochondrial large ribosomal subunit [PMID:12392552]
note: Mitochondrial ribosomal protein of the large subunit; conserved in metazoa, with similarity to human mitochondrial ribosomal protein MRPL49
codon start: 1
product: mitochondrial 54S ribosomal protein IMG2
translation: MISSCVTRCFGRGKCLPGPATASIYQTIRCISTNSNKAAEAPIFPKLEDVKMHELIGNNNFGKKTYYVERSRTGNLPVYSAYKNGGNKIITEIRKIEGDVIQLRNDLQEQLPFIPKKSWSVVMQSKKIIIKGNAVEAVKRVLTKKF
SIO_010081: YCR071C
subclass of: SO_0000673
so part of: YCR071C
location: complement(240103..240543)
location: region:240103-240543:-1
so has part: feature:240103-240543:-1:exon

NP_009996.2
type: Protein
SIO_000068: ncbiprotein

S000000667
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:240103-240543:-1:exon

YCR072C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RSA4
locus tag: YCR072C
so part of: sequence
location: complement(<240805..>242352)
location: region:240805-242352:-1
so has part: feature:240805-242352:-1:exon
subclass of: SO_0000010

850435
type: Gene
SIO_000068: ncbigene

position:240805:-1
position: 240805
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:242352:-1
position: 242352
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:240805-242352:-1:exon

YCR072C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RSA4
locus tag: YCR072C
product: Rsa4p
transcript id: NM_001178782.1
SIO_010081: YCR072C
subclass of: SO_0000673
so part of: YCR072C
location: complement(<240805..>242352)
location: region:240805-242352:-1
so has part: feature:240805-242352:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:240805-242352:-1:exon

YCR072C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RSA4
locus tag: YCR072C
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:16221974]
experiment: EXISTENCE:mutant phenotype:GO:0000027 ribosomal large subunit assembly [PMID:16221974]
experiment: EXISTENCE:mutant phenotype:GO:0110136 protein-RNA complex remodeling [PMID:19737519]
note: Ribosomal large subunit (60S) assembly factor; association of the N-terminal ubiquitin-like (UBL) domain of this preribosomal factor with the MIDAS domain in the Rea1p tail, promoted by the GTPase Nog2p, is required for the ATP-dependent dissociation of preribosomal factors including the Rix1p subcomplex, Rea1p, Nog2p and Rsa1p itself prior to nuclear export of pre-60S particles; contains WD-repeats and a UBL domain; localizes to the nucleolus
codon start: 1
product: Rsa4p
translation: MSTLIPPPSKKQKKEAQLPREVAIIPKDLPNVSIKFQALDTGDNVGGALRVPGAISEKQLEELLNQLNGTSDDPVPYTFSCTIQGKKASDPVKTIDITDNLYSSLIKPGYNSTEDQITLLYTPRAVFKVKPVTRSSSAIAGHGSTILCSAFAPHTSSRMVTGAGDNTARIWDCDTQTPMHTLKGHYNWVLCVSWSPDGEVIATGSMDNTIRLWDPKSGQCLGDALRGHSKWITSLSWEPIHLVKPGSKPRLASSSKDGTIKIWDTVSRVCQYTMSGHTNSVSCVKWGGQGLLYSGSHDRTVRVWDINSQGRCINILKSHAHWVNHLSLSTDYALRIGAFDHTGKKPSTPEEAQKKALENYEKICKKNGNSEEMMVTASDDYTMFLWNPLKSTKPIARMTGHQKLVNHVAFSPDGRYIVSASFDNSIKLWDGRDGKFISTFRGHVASVYQVAWSSDCRLLVSCSKDTTLKVWDVRTRKLSVDLPGHKDEVYTVDWSVDGKRVCSGGKDKMVRLWTH
SIO_010081: YCR072C
subclass of: SO_0000673
so part of: YCR072C
location: complement(240805..242352)
location: region:240805-242352:-1
so has part: feature:240805-242352:-1:exon

NP_009997.2
type: Protein
SIO_000068: ncbiprotein

S000000668
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:240805-242352:-1:exon

YCR073C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SSK22
locus tag: YCR073C
so part of: sequence
location: complement(<242588..>246583)
location: region:242588-246583:-1
so has part: feature:242588-246583:-1:exon
subclass of: SO_0000010

850436
type: Gene
SIO_000068: ncbigene

position:242588:-1
position: 242588
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:246583:-1
position: 246583
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:242588-246583:-1:exon

YCR073C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SSK22
locus tag: YCR073C
product: mitogen-activated protein kinase kinase kinase SSK22
transcript id: NM_001178783.1
SIO_010081: YCR073C
subclass of: SO_0000673
so part of: YCR073C
location: complement(<242588..>246583)
location: region:242588-246583:-1
so has part: feature:242588-246583:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:242588-246583:-1:exon

YCR073C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SSK22
locus tag: YCR073C
EC number: 2.7.11.1
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:16319894]
experiment: EXISTENCE:direct assay:GO:0006468 protein phosphorylation [PMID:16319894]
experiment: EXISTENCE:genetic interaction:GO:0000161 osmosensory signaling MAPK cascade [PMID:7624781|PMID:9742096]
experiment: EXISTENCE:mutant phenotype:GO:0000161 osmosensory signaling MAPK cascade [PMID:7624781]
note: MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; functionally redundant with Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p; SSK22 has a paralog, SSK2, that arose from the whole genome duplication
codon start: 1
product: mitogen-activated protein kinase kinase kinase SSK22
translation: MMMDILNTQQQKAAEGGRVLAPHTISSKLVKRLSSHSSHKLSRSDLKALGGSETISDGPSQLTFKDRYVFNESLYLKKLKKTALDDYYTRGIKLTNRYEEDDGDDEIIRLSNGDRIDEDLHSGVKFFSTTPYCRKMRSDSDELAWNEIATERFKWQSMLARVLKGDIVKGEKTRIANQVKKPGLNKELSDEIWLELKAWLNGRTMQEMEQSLTYLRDSSDSVFEEIMKFQIPQGKILSLDALEAILQDLMNRYHSVVSYWPNLKKMYKDKPITNTAEFTARIDVMNSWLNFKTNLTLRRQELDDWINRFSPISSSDNCQEDFDGVPQWNCKMKILAEQLMKEKNIESIFQKKIFYPLSPWMFKLKLHFIVYRETLTKMNIKYPYERLRSLLAFPVYLIKEVILTRLSYARKLKNPTMMMIDQMIDDFNAFIRLSVQLKYTLTKYCSNLPFDVDFDPTFENTVIEAIRYLFFLLNLKLIDSSKQNFKAPDLLLKYWDHLKNTGHYINGAETVIPNEFLKLTLRLVHKLQFYLLKQQNFPPTFANASEAEKWLSSIFENLGAMKRKLNRFSNILVKAFQNSAVYQINHNAQLVKKLKDAHYFLVYSGNTFESSGVYMFAAPELLGCDNDTILRILRNKSIGCDLVPKLDIGNNLNVYDITTKETDLNILVSKGEDSKGIPYYRVVANSSSDLDRHAHQSKKKNFSTDPFDQHLDEKNNEVFELEVALSSLGALVVLYPGEPVVWDGPVYKLPGNNLFASNEMDLGKIGNPNTLILLNQGSNYALTYQIDKFNQTVGDSVSFIEKRCSLNSIESSLQKINKAYYKLTYTVLNNYKGILGSFMKQCPGNELLNSIFMFGRDFGRSFLKYNAFSSKRKYVIIFLMVKLGMNWLKFLVEECDPTDQRTFRWCVLAMDFAMQMTSGYNILALNVKQFQELKERVSVCMSLLISHFDVMGARATEAENGMQQARLNIDTEENIDEEATLEINSRLRLEAIKTLEKTMKRNPRQMGKVLDATDQGNKYLLSLASSLSNVSMRWQKRSFIGGGTFGQVYSAINLENGEILAVKEIKIHDTTTMKKIFPLIKEEMTVLEMLNHPNIVQYYGVEVHRDKVNIFMEYCEGGSLASLLDHGRIEDEMVTQVYTFELLEGLAYLHQSGVVHRDIKPENILLDFNGIIKYVDFGTARTVVGSRTRTVRNAAVQDFGVETKSLNEMMGTPMYMAPETISGSAVKGKLGADDVWALGCVVLEMATGRRPWSNLDNEWAIMYHVAAGRIPQLPNRDEMTAAGRAFLERCLVQDPTMRATAVELLIDPWMIQIREIAFGNSEKDQVPILSS
SIO_010081: YCR073C
subclass of: SO_0000673
so part of: YCR073C
location: complement(242588..246583)
location: region:242588-246583:-1
so has part: feature:242588-246583:-1:exon

NP_009998.2
type: Protein
SIO_000068: ncbiprotein

S000000669
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:242588-246583:-1:exon

YCR073W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YCRX13W
gene: SOL2
locus tag: YCR073W-A
gene synonym: YCRX13W
so part of: sequence
location: <246963..>247910
location: region:246963-247910:1
so has part: feature:246963-247910:1:exon
subclass of: SO_0000010

850437
type: Gene
SIO_000068: ncbigene

position:246963:1
position: 246963
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:247910:1
position: 247910
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:246963-247910:1:exon

YCR073W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YCRX13W
gene: SOL2
locus tag: YCR073W-A
gene synonym: YCRX13W
product: Sol2p
transcript id: NM_001178815.1
SIO_010081: YCR073W-A
subclass of: SO_0000673
so part of: YCR073W-A
location: <246963..>247910
location: region:246963-247910:1
so has part: feature:246963-247910:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:246963-247910:1:exon

YCR073W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YCRX13W
gene: SOL2
locus tag: YCR073W-A
gene synonym: YCRX13W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:15454531]
experiment: EXISTENCE:mutant phenotype:GO:0006409 tRNA export from nucleus [PMID:15454531]
note: Protein with a possible role in tRNA export; shows similarity to 6-phosphogluconolactonase non-catalytic domains but does not exhibit this enzymatic activity; homologous to Sol3p and Sol4p; SOL2 has a paralog, SOL1, that arose from the whole genome duplication
codon start: 1
product: Sol2p
translation: MTTTVPKIFAFHEFSDVAEAVADHVVHAQDGALAPKNERKHSVPNISMNALDMTREASCKSTASAAEGKSGSSGSGSGSSKPKKEKRFKIALSGGSLIEVLHEGLLKRDDVRWGDWDIYFADERLVPFSSNESNYGCAKRKILDLIDTAKYGTPKVYHIDESLIDDPQECADNYEKVLIRGFAGRDSVKLPMFDLFLLGCAPDGHIASLFPNFQDNLREKLAWVVPVENAPSGPSTRISLTIPVICHSHRVTFVVEGATKAPIIKTIMERPEKGLPSSIVNEGAAGRVSWFVDDDALTDVLVTKKKYKFHQGLSI
SIO_010081: YCR073W-A
subclass of: SO_0000673
so part of: YCR073W-A
location: 246963..247910
location: region:246963-247910:1
so has part: feature:246963-247910:1:exon

NP_009999.2
type: Protein
SIO_000068: ncbiprotein

S000000718
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:246963-247910:1:exon

YCR075C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ERS1
locus tag: YCR075C
so part of: sequence
location: complement(<248033..>248815)
location: region:248033-248815:-1
so has part: feature:248033-248815:-1:exon
subclass of: SO_0000010

850438
type: Gene
SIO_000068: ncbigene

position:248033:-1
position: 248033
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:248815:-1
position: 248815
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:248033-248815:-1:exon

YCR075C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ERS1
locus tag: YCR075C
product: cystinosin-like protein ERS1
transcript id: NM_001178784.1
SIO_010081: YCR075C
subclass of: SO_0000673
so part of: YCR075C
location: complement(<248033..>248815)
location: region:248033-248815:-1
so has part: feature:248033-248815:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:248033-248815:-1:exon

YCR075C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ERS1
locus tag: YCR075C
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:15885099|PMID:27142334]
experiment: EXISTENCE:direct assay:GO:0005768 endosome [PMID:15885099]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:27142334]
experiment: EXISTENCE:direct assay:GO:0015811 L-cystine transport [PMID:27142334]
experiment: EXISTENCE:genetic interaction:GO:0015184 L-cystine transmembrane transporter activity [PMID:15885099]
experiment: EXISTENCE:genetic interaction:GO:0015811 L-cystine transport [PMID:15885099]
note: Protein involved in cystine transport; localizes to the vacuole, plasma membrane and endosome; similarity to human cystinosin, a H(+)-driven transporter involved in L-cystine export from lysosomes and implicated in the disease cystinosis; contains seven transmembrane domains; mutation is functionally complemented by human CTNS
codon start: 1
product: cystinosin-like protein ERS1
translation: MVSLDDILGIVYVTSWSISMYPPIITNWRHKSASAISMDFVMLNTAGYSYLVISIFLQLYCWKMTGDESDLGRPKLTQFDFWYCLHGCLMNVVLLTQVVAGARIWRFPGKGHRKMNPWYLRILLASLAIFSLLTVQFMYSNYWYDWHNSRTLAYCNNLFLLKISMSLIKYIPQVTHNSTRKSMDCFPIQGVFLDVTGGIASLLQLIWQLSNDQGFSLDTFVTNFGKVGLSMVTLIFNFIFIMQWFVYRSRGHDLASEYPL
SIO_010081: YCR075C
subclass of: SO_0000673
so part of: YCR075C
location: complement(248033..248815)
location: region:248033-248815:-1
so has part: feature:248033-248815:-1:exon

NP_010000.1
type: Protein
SIO_000068: ncbiprotein

S000000671
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:248033-248815:-1:exon

YCR075W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: EGO2
locus tag: YCR075W-A
so part of: sequence
location: <248975..>249202
location: region:248975-249202:1
so has part: feature:248975-249202:1:exon
subclass of: SO_0000010

1466399
type: Gene
SIO_000068: ncbigene

position:248975:1
position: 248975
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:249202:1
position: 249202
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:248975-249202:1:exon

YCR075W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: EGO2
locus tag: YCR075W-A
product: Ego2p
transcript id: NM_001184529.1
SIO_010081: YCR075W-A
subclass of: SO_0000673
so part of: YCR075W-A
location: <248975..>249202
location: region:248975-249202:1
so has part: feature:248975-249202:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:248975-249202:1:exon

YCR075W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: EGO2
locus tag: YCR075W-A
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:26206314]
experiment: EXISTENCE:mutant phenotype:GO:0038202 TORC1 signaling [PMID:26206314]
experiment: EXISTENCE:mutant phenotype:GO:0072665 protein localization to vacuole [PMID:26206314]
experiment: EXISTENCE:physical interaction:GO:0071986 Ragulator complex [PMID:26206314]
note: Subunit of the EGO/GSE complex; the vacuolar/endosomal membrane associated EGO/GSE complex regulates exit from rapamycin-induced growth arrest, stimulating microautophagy and sorting of Gap1p from the endosome to the plasma membrane; identified by homology to Ashbya gossypii; EGO2 has a paralog, EGO4, that arose from the whole genome duplication
codon start: 1
product: Ego2p
translation: MEAEKQSDIKGTIAFDTHGNVIESTGVGSQRIEDIGDLSKVTLDAEGFAQVQGDSLLVHLYKRNDITLAVYTSAQ
SIO_010081: YCR075W-A
subclass of: SO_0000673
so part of: YCR075W-A
location: 248975..249202
location: region:248975-249202:1
so has part: feature:248975-249202:1:exon

NP_878058.1
type: Protein
SIO_000068: ncbiprotein

S000028519
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:248975-249202:1:exon

YCR076C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FUB1
locus tag: YCR076C
so part of: sequence
location: complement(<249293..>250045)
location: region:249293-250045:-1
so has part: feature:249293-250045:-1:exon
subclass of: SO_0000010

850439
type: Gene
SIO_000068: ncbigene

position:249293:-1
position: 249293
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:250045:-1
position: 250045
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:249293-250045:-1:exon

YCR076C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FUB1
locus tag: YCR076C
product: Fub1p
transcript id: NM_001178785.1
SIO_010081: YCR076C
subclass of: SO_0000673
so part of: YCR076C
location: complement(<249293..>250045)
location: region:249293-250045:-1
so has part: feature:249293-250045:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:249293-250045:-1:exon

YCR076C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FUB1
locus tag: YCR076C
experiment: EXISTENCE:direct assay:GO:0070628 proteasome binding [PMID:22362029]
note: Proteasome-binding protein; interacts physically with multiple subunits of the 20S proteasome and genetically with genes encoding 20S core particle and 19S regulatory particle subunits; specifically blocks all three proteasome active sites; exhibits boundary activity which inhibits the propagation of heterochromatic silencing; contains a PI31 proteasome regulator domain and sequence similarity with human PSMF1, a proteasome inhibitor; not an essential gene
codon start: 1
product: Fub1p
translation: MIENKVELVAELVLESIGKTEVVSRHTEGTKSCQVSFRIKDSPSEKGSTSFLSELVVIQTLDDNDKYTVVIRHGTSITMACVVGYSDFKLPTELKWPLERESLPVEPDLKPIMTQLKRQTAGSADMPKFDDEYQAQARQNQGTAPLNPYPGLTVTEPSFANPAGGYADGDLYPVGTSHPDWSGGLPNPLGNPSSQGGMIFDPNRRPAPRREDMPPGWMPGSKYDEPFGPGSGGFGGSGSGGFGGSGSGFI
SIO_010081: YCR076C
subclass of: SO_0000673
so part of: YCR076C
location: complement(249293..250045)
location: region:249293-250045:-1
so has part: feature:249293-250045:-1:exon

NP_010001.1
type: Protein
SIO_000068: ncbiprotein

S000000672
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:249293-250045:-1:exon

YCR077C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MRT1
gene: PAT1
locus tag: YCR077C
gene synonym: MRT1
so part of: sequence
location: complement(<250238..>252628)
location: region:250238-252628:-1
so has part: feature:250238-252628:-1:exon
subclass of: SO_0000010

850440
type: Gene
SIO_000068: ncbigene

position:250238:-1
position: 250238
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:252628:-1
position: 252628
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:250238-252628:-1:exon

YCR077C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MRT1
gene: PAT1
locus tag: YCR077C
gene synonym: MRT1
product: Pat1p
transcript id: NM_001178786.2
SIO_010081: YCR077C
subclass of: SO_0000673
so part of: YCR077C
location: complement(<250238..>252628)
location: region:250238-252628:-1
so has part: feature:250238-252628:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:250238-252628:-1:exon

YCR077C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MRT1
gene: PAT1
locus tag: YCR077C
gene synonym: MRT1
experiment: EXISTENCE:direct assay:GO:0000776 kinetochore [PMID:23893485]
experiment: EXISTENCE:direct assay:GO:0000932 P-body [PMID:12730603]
experiment: EXISTENCE:direct assay:GO:0003682 chromatin binding [PMID:23706738]
experiment: EXISTENCE:direct assay:GO:0003723 RNA binding [PMID:25035297]
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:23706738]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:23706738|PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0010494 cytoplasmic stress granule [PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0022627 cytosolic small ribosomal subunit [PMID:10779343]
experiment: EXISTENCE:direct assay:GO:0045947 negative regulation of translational initiation [PMID:20832728]
experiment: EXISTENCE:direct assay:GO:1990726 Lsm1-7-Pat1 complex [PMID:24139796]
experiment: EXISTENCE:genetic interaction:GO:0033962 P-body assembly [PMID:18981231]
experiment: EXISTENCE:mutant phenotype:GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA [PMID:10913177]
experiment: EXISTENCE:mutant phenotype:GO:0000932 P-body [PMID:12730603]
experiment: EXISTENCE:mutant phenotype:GO:0001731 formation of translation preinitiation complex [PMID:20832728]
experiment: EXISTENCE:mutant phenotype:GO:0006446 regulation of translational initiation [PMID:10779343]
experiment: EXISTENCE:mutant phenotype:GO:0033962 P-body assembly [PMID:18981231]
experiment: EXISTENCE:mutant phenotype:GO:0045947 negative regulation of translational initiation [PMID:20832728]
experiment: EXISTENCE:physical interaction:GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA [PMID:10913177]
experiment: EXISTENCE:physical interaction:GO:0005515 protein binding [PMID:26952104]
note: Deadenylation-dependent mRNA-decapping factor; also required for faithful chromosome transmission, maintenance of rDNA locus stability, and protection of mRNA 3'-UTRs from trimming; associated with topoisomerase II; binds to mRNAs under glucose starvation, most often in the 3' UTR; functionally linked to Pab1p; forms cytoplasmic foci upon DNA replication stress; phosphorylation by PKA inhibits P body foci formation
codon start: 1
product: Pat1p
translation: MSFFGLENSGNARDGPLDFEESYKGYGEHELEENDYLNDETFGDNVQVGTDFDFGNPHSSGSSGNAIGGNGVGATARSYVAATAEGISGPRTDGTAAAGPLDLKPMESLWSTAPPPAMAPSPQSTMAPAPAPQQMAPLQPILSMQDLERQQRQMQQQFMNFHAMGHPQGLPQGPPQQQFPMQPASGQPGPSQFAPPPPPPGVNVNMNQMPMGPVQVPVQASPSPIGMSNTPSPGPVVGATKMPLQSGRRSKRDLSPEEQRRLQIRHAKVEKILKYSGLMTPRDKDFITRYQLSQIVTEDPYNEDFYFQVYKIIQRGGITSESNKGLIARAYLEHSGHRLGGRYKRTDIALQRMQSQVEKAVTVAKERPSKLKDQQAAAGNSSQDNKQANTVLGKISSTLNSKNPRRQLQIPRQQPSDPDALKDVTDSLTNVDLASSGSSSTGSSAAAVASKQRRRSSYAFNNGNGATNLNKSGGKKFILELIETVYEEILDLEANLRNGQQTDSTAMWEALHIDDSSYDVNPFISMLSFDKGIKIMPRIFNFLDKQQKLKILQKIFNELSHLQIIILSSYKTTPKPTLTQLKKVDLFQMIILKIIVSFLSNNSNFIEIMGLLLQLIRNNNVSFLTTSKIGLNLITILISRAALIKQDSSRSNILSSPEISTWNEIYDKLFTSLESKIQLIFPPREYNDHIMRLQNDKFMDEAYIWQFLASLALSGKLNHQRIIIDEVRDEIFATINEAETLQKKEKELSVLPQRSQELDTELKSIIYNKEKLYQDLNLFLNVMGLVYRDGEISELK
SIO_010081: YCR077C
subclass of: SO_0000673
so part of: YCR077C
location: complement(250238..252628)
location: region:250238-252628:-1
so has part: feature:250238-252628:-1:exon

NP_010002.3
type: Protein
SIO_000068: ncbiprotein

S000000673
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:250238-252628:-1:exon

YCR079W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: AUP1
alternative label: PPP2
gene: PTC6
locus tag: YCR079W
gene synonym: AUP1; PPP2
so part of: sequence
location: <252845..>254173
location: region:252845-254173:1
so has part: feature:252845-254173:1:exon
subclass of: SO_0000010

850441
type: Gene
SIO_000068: ncbigene

position:252845:1
position: 252845
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:254173:1
position: 254173
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:252845-254173:1:exon

YCR079W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: AUP1
alternative label: PPP2
gene: PTC6
locus tag: YCR079W
gene synonym: AUP1; PPP2
product: type 2C protein phosphatase PTC6
transcript id: NM_001180034.1
SIO_010081: YCR079W
subclass of: SO_0000673
so part of: YCR079W
location: <252845..>254173
location: region:252845-254173:1
so has part: feature:252845-254173:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:252845-254173:1:exon

YCR079W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: AUP1
alternative label: PPP2
gene: PTC6
locus tag: YCR079W
gene synonym: AUP1; PPP2
EC number: 3.1.3.16
EC number: 3.1.3.43
experiment: EXISTENCE:direct assay:GO:0004722 protein serine/threonine phosphatase activity [PMID:17002782]
experiment: EXISTENCE:direct assay:GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity [PMID:28539364]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:24769239|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005758 mitochondrial intermembrane space [PMID:17166847]
experiment: EXISTENCE:direct assay:GO:0005759 mitochondrial matrix [PMID:18180296]
experiment: EXISTENCE:genetic interaction:GO:0016236 macroautophagy [PMID:17166847]
experiment: EXISTENCE:mutant phenotype:GO:0000422 autophagy of mitochondrion [PMID:17166847]
experiment: EXISTENCE:mutant phenotype:GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity [PMID:18180296]
experiment: EXISTENCE:mutant phenotype:GO:0070262 peptidyl-serine dephosphorylation [PMID:18180296]
experiment: EXISTENCE:mutant phenotype:GO:1901524 regulation of mitophagy [PMID:31548421]
experiment: EXISTENCE:mutant phenotype:GO:1904184 positive regulation of pyruvate dehydrogenase activity [PMID:18180296]
note: Mitochondrial type 2C protein phosphatase (PP2C); has similarity to mammalian PP1Ks; involved in mitophagy; null mutant is sensitive to rapamycin and has decreased phosphorylation of the Pda1 subunit of pyruvate dehydrogenase
codon start: 1
product: type 2C protein phosphatase PTC6
translation: MRLGNAYAYCKPSQNVGLKLDLLRGLPGYVGHATSRINRLENQDNYSIKMMRSWPNAYGSALNCSVFDGHGEKGAQLSQLLADKLCSSLDFPEPSWDKQDLKKLVQEYARRFPEGNYWKHKLSTFEKFYNKFIKNCNSKQELLLMKEGDSAILGQNGGRMIFDKMGNIIDKIALLTELDRLRLFYGFARFDLDQCCGLGTAAGSTASSIFLYPYDDPNAPIDEGKDDDSWIISHSGLLKLIVTQVGDSKIILCDQDGIAHALTTTHHINSSRERHRLSIDPSRLDPDAFGETRFLNNFANTRSFGDVAGKPYGISSEPDIFSFLVGNTLHLPRSERSKLPFNGDECFLALVTDGITNKLADQEVVDLITSTVNSWGLKKATPQFVAEETIKFIQAIATKHSDNATCVVVRLSNWGNWPNVDRTGPQRETKLMNAQSNETKLN
SIO_010081: YCR079W
subclass of: SO_0000673
so part of: YCR079W
location: 252845..254173
location: region:252845-254173:1
so has part: feature:252845-254173:1:exon

NP_010003.2
type: Protein
SIO_000068: ncbiprotein

S000002133
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:252845-254173:1:exon

YCR081W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: GIG1
alternative label: MED12
alternative label: NUT6
alternative label: SSN5
alternative label: YCR080W
gene: SRB8
locus tag: YCR081W
gene synonym: GIG1; MED12; NUT6; SSN5; YCR080W
so part of: sequence
location: <254371..>258654
location: region:254371-258654:1
so has part: feature:254371-258654:1:exon
subclass of: SO_0000010

850442
type: Gene
SIO_000068: ncbigene

position:254371:1
position: 254371
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:258654:1
position: 258654
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:254371-258654:1:exon

YCR081W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: GIG1
alternative label: MED12
alternative label: NUT6
alternative label: SSN5
alternative label: YCR080W
gene: SRB8
locus tag: YCR081W
gene synonym: GIG1; MED12; NUT6; SSN5; YCR080W
product: Srb8p
transcript id: NM_001178787.1
SIO_010081: YCR081W
subclass of: SO_0000673
so part of: YCR081W
location: <254371..>258654
location: region:254371-258654:1
so has part: feature:254371-258654:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:254371-258654:1:exon

YCR081W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: GIG1
alternative label: MED12
alternative label: NUT6
alternative label: SSN5
alternative label: YCR080W
gene: SRB8
locus tag: YCR081W
gene synonym: GIG1; MED12; NUT6; SSN5; YCR080W
experiment: EXISTENCE:direct assay:GO:0003713 transcription coactivator activity [PMID:20505076]
experiment: EXISTENCE:direct assay:GO:0016592 mediator complex [PMID:11383511|PMID:12200444]
experiment: EXISTENCE:mutant phenotype:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:16109375]
experiment: EXISTENCE:mutant phenotype:GO:0000411 positive regulation of transcription by galactose [PMID:15601835]
experiment: EXISTENCE:mutant phenotype:GO:0003713 transcription coactivator activity [PMID:20505076]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:15601835]
note: Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; involved in glucose repression
codon start: 1
product: Srb8p
translation: MNNGSGRYLLTPPDDLHPYVPSSKPQEQVYPDFKPWEHTAAEDQILANFVAKGFYHTPMVNFESISARSSVHESLVTQSNILSQQFDKIIKIREDHINKIPSNSTTTLHGPGFQLPNRITLTDHRKETWLHELSSSHTSLVKIGKFIPHGLKRRQVIEQCYLKFIPLKRAIWLIKCCYFIEWKSNHKKKRSNAAGADDAISMHLLKDWTDTFVYILEKLIFDMTNHYNDSQQLRTWKRQISYFLKLLGNCYSLRLINKEIFHHWLVEFINKMENFEFLPLSLHILMIFWNDICQIDTNAPVAATITSSQKEPFFLVTKITDMLLHKYYIVSSSKSMINDENYIINDIKKNNKIKLNILKILSSLILKIFQEQSLEVFIFPTSNWEIYKPLLFEIVSNADTNQNSDMKKKLELISYRNESLKNNSSIRNVIMSASNANDFQLTIVTCKQFPKLSCIQLNCIDTQFTKLLDDNPTEFDWPTYVDQNPLTMHKIIQLILWSIHPSRQFDHYESNQLVAKLLLLRINSTDEDLHEFQIEDAIWSLVFQLAKNFSAQKRVVSYMMPSLYRLLNILITYGIIKVPTYIRKLISSGLLYLQDSNDKFVHVQLLINLKISPLMKSQYNMVLRNVMEYDVKFYEIFNFDQLVEITEQIKMRILSNDITNLQLSKTPLSIKIMVAEWYLSHLCSGILSSVNRTVLLKIFKIFCIDLEVFHHFFKWIEFIVYHQLLSDIESLEALMDILLCYQKLFSQFINDHILFTKTFIFIYKKVLKEKDVPAYNVTSFMPFWKFFMKNFPFVLKVDNDLRIELQSVYNDEKLKTEKLKNDKSEVLKVYSMINNSNQAVGQTWNFPEVFQVNIRFLLHNSEIIDTNTSKQFQKARNNVMLLIATNLKEYNKFMSIFLKRKDFTNKNLIQLISLKLLTFEVTQNVLGLEYIIRLLPINLENNDGSYGLFLKYHKEQFIKSNFEKILLTCYELEKKYHGNECEINYYEILLKILITYGSSPKLLATSTKIIMLLLNDSVENSSNILEDILYYSTCPSETDLNDIPLGSGQPDNDTVVTNDDKSDDDDHTVDEIDHVEYYVMMDFANLWVFQAFTCFCIKKIMENNEPAMAMEDLKNFIFQIIEITNSNDLCSQIFDQLKDMQTIEMITQIVEKDFCTSCLQNNNQKIDDNYIVVVIEIITSLSMRFQRETSGMIVISMENYHLLIKIIRQLSELNEGNLSKREIQIDAVLKIFSFHQDSIFQRIIADLSADKPTSPFIDSICKLFDKISFNLRLKLFLYEILSSLKSFAIYSSTIDAPAFHTSGKVELPKKLLNLPPFQVSSFVKETKLHSGDYGEEEDADQEESFSLNLGIGIVEIAHENEQKWLIYDKKDHKYVCTFSMEPYHFISNYNTKYTDDMATGSNDTTAFNDSCVNLSLFDARFERKNPH
SIO_010081: YCR081W
subclass of: SO_0000673
so part of: YCR081W
location: 254371..258654
location: region:254371-258654:1
so has part: feature:254371-258654:1:exon

NP_010004.1
type: Protein
SIO_000068: ncbiprotein

S000000677
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:254371-258654:1:exon

YCR082W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: AHC2
locus tag: YCR082W
so part of: sequence
location: <258883..>259269
location: region:258883-259269:1
so has part: feature:258883-259269:1:exon
subclass of: SO_0000010

850443
type: Gene
SIO_000068: ncbigene

position:258883:1
position: 258883
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:259269:1
position: 259269
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:258883-259269:1:exon

YCR082W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: AHC2
locus tag: YCR082W
product: Ahc2p
transcript id: NM_001178788.1
SIO_010081: YCR082W
subclass of: SO_0000673
so part of: YCR082W
location: <258883..>259269
location: region:258883-259269:1
so has part: feature:258883-259269:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:258883-259269:1:exon

YCR082W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: AHC2
locus tag: YCR082W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:16464826]
experiment: EXISTENCE:direct assay:GO:0140110 transcription regulator activity [PMID:16464826]
experiment: EXISTENCE:mutant phenotype:GO:0140671 ADA complex [PMID:21734642]
experiment: EXISTENCE:physical interaction:GO:0016573 histone acetylation [PMID:21734642]
experiment: EXISTENCE:physical interaction:GO:0140671 ADA complex [PMID:21734642]
note: Component of the ADA histone acetyltransferase complex; Ahc2p and Ahc1p are unique to the ADA complex and not shared with the related SAGA and SLIK complexes; may tether Ahc1p to the complex
codon start: 1
product: Ahc2p
translation: MITPKGTHDAVAKFQKTDLHQDLDYIVLQQRRTQLETLINERESFVKNLCSLFHKIQNTKNYQEFVDVLAENRDLLREIFTVENGFQKQKWISNDDIPQIDWDKFALDINAYIAENDQLLALYEDGLL
SIO_010081: YCR082W
subclass of: SO_0000673
so part of: YCR082W
location: 258883..259269
location: region:258883-259269:1
so has part: feature:258883-259269:1:exon

NP_010005.1
type: Protein
SIO_000068: ncbiprotein

S000000678
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:258883-259269:1:exon

YCR083W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TRX3
locus tag: YCR083W
so part of: sequence
location: <259578..>259961
location: region:259578-259961:1
so has part: feature:259578-259961:1:exon
subclass of: SO_0000010

850444
type: Gene
SIO_000068: ncbigene

position:259578:1
position: 259578
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:259961:1
position: 259961
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:259578-259961:1:exon

YCR083W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TRX3
locus tag: YCR083W
product: Trx3p
transcript id: NM_001178789.1
SIO_010081: YCR083W
subclass of: SO_0000673
so part of: YCR083W
location: <259578..>259961
location: region:259578-259961:1
so has part: feature:259578-259961:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:259578-259961:1:exon

YCR083W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TRX3
locus tag: YCR083W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:10037727|PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0015036 disulfide oxidoreductase activity [PMID:10037727]
experiment: EXISTENCE:mutant phenotype:GO:0034599 cellular response to oxidative stress [PMID:10037727]
note: Mitochondrial thioredoxin; highly conserved oxidoreductase required to maintain the redox homeostasis of the cell, forms the mitochondrial thioredoxin system with Trr2p, redox state is maintained by both Trr2p and Glr1p
codon start: 1
product: Trx3p
translation: MLFYKPVMRMAVRPLKSIRFQSSYTSITKLTNLTEFRNLIKQNDKLVIDFYATWCGPCKMMQPHLTKLIQAYPDVRFVKCDVDESPDIAKECEVTAMPTFVLGKDGQLIGKIIGANPTALEKGIKDL
SIO_010081: YCR083W
subclass of: SO_0000673
so part of: YCR083W
location: 259578..259961
location: region:259578-259961:1
so has part: feature:259578-259961:1:exon

NP_010006.1
type: Protein
SIO_000068: ncbiprotein

S000000679
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:259578-259961:1:exon

YCR084C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: AAR1
alternative label: AER2
alternative label: AMM1
alternative label: CRT4
alternative label: CYC9
alternative label: FLK1
alternative label: ROX4
alternative label: SFL2
alternative label: UMR7
gene: TUP1
locus tag: YCR084C
gene synonym: AAR1; AER2; AMM1; CRT4; CYC9; FLK1; ROX4; SFL2; UMR7
so part of: sequence
location: complement(<260311..>262452)
location: region:260311-262452:-1
so has part: feature:260311-262452:-1:exon
subclass of: SO_0000010

850445
type: Gene
SIO_000068: ncbigene

position:260311:-1
position: 260311
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:262452:-1
position: 262452
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:260311-262452:-1:exon

YCR084C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: AAR1
alternative label: AER2
alternative label: AMM1
alternative label: CRT4
alternative label: CYC9
alternative label: FLK1
alternative label: ROX4
alternative label: SFL2
alternative label: UMR7
gene: TUP1
locus tag: YCR084C
gene synonym: AAR1; AER2; AMM1; CRT4; CYC9; FLK1; ROX4; SFL2; UMR7
product: chromatin-silencing transcriptional regulator TUP1
transcript id: NM_001178790.1
SIO_010081: YCR084C
subclass of: SO_0000673
so part of: YCR084C
location: complement(<260311..>262452)
location: region:260311-262452:-1
so has part: feature:260311-262452:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:260311-262452:-1:exon

YCR084C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: AAR1
alternative label: AER2
alternative label: AMM1
alternative label: CRT4
alternative label: CYC9
alternative label: FLK1
alternative label: ROX4
alternative label: SFL2
alternative label: UMR7
gene: TUP1
locus tag: YCR084C
gene synonym: AAR1; AER2; AMM1; CRT4; CYC9; FLK1; ROX4; SFL2; UMR7
experiment: EXISTENCE:direct assay:GO:0003714 transcription corepressor activity [PMID:9741624]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:1739976]
experiment: EXISTENCE:direct assay:GO:0036033 mediator complex binding [PMID:11226276]
experiment: EXISTENCE:direct assay:GO:0042393 histone binding [PMID:8675011]
experiment: EXISTENCE:direct assay:GO:0042826 histone deacetylase binding [PMID:14525981]
experiment: EXISTENCE:direct assay:GO:0080025 phosphatidylinositol-3,5-bisphosphate binding [PMID:21536737]
experiment: EXISTENCE:mutant phenotype:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:18708352|PMID:1900249|PMID:9858577|PMID:9560430|PMID :1312982]
experiment: EXISTENCE:mutant phenotype:GO:0000433 carbon catabolite repression of transcription from RNA polymerase II promoter by glucose [PMID:9461460]
experiment: EXISTENCE:mutant phenotype:GO:0003714 transcription corepressor activity [PMID:9741624]
experiment: EXISTENCE:mutant phenotype:GO:0006357 regulation of transcription by RNA polymerase II [PMID:9280286]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:26546823]
experiment: EXISTENCE:mutant phenotype:GO:2001020 regulation of response to DNA damage stimulus [PMID:9741624]
experiment: EXISTENCE:physical interaction:GO:0017053 transcription repressor complex [PMID:9111019]
experiment: EXISTENCE:physical interaction:GO:0036033 mediator complex binding [PMID:11226276]
experiment: EXISTENCE:physical interaction:GO:0042826 histone deacetylase binding [PMID:14525981]
note: General repressor of transcription in complex with Cyc8p; involved in the establishment of repressive chromatin structure through interactions with histones H3 and H4 and stabilization of nucleosomes over promoters; appears to enhance expression of mating-related genes; functions as a coactivator in certain situations
codon start: 1
product: chromatin-silencing transcriptional regulator TUP1
translation: MTASVSNTQNKLNELLDAIRQEFLQVSQEANTYRLQNQKDYDFKMNQQLAEMQQIRNTVYELELTHRKMKDAYEEEIKHLKLGLEQRDHQIASLTVQQQRQQQQQQQVQQHLQQQQQQLAAASASVPVAQQPPATTSATATPAANTTTGSPSAFPVQASRPNLVGSQLPTTTLPVVSSNAQQQLPQQQLQQQQLQQQQPPPQVSVAPLSNTAINGSPTSKETTTLPSVKAPESTLKETEPENNNTSKINDTGSATTATTTTATETEIKPKEEDATPASLHQDHYLVPYNQRANHSKPIPPFLLDLDSQSVPDALKKQTNDYYILYNPALPREIDVELHKSLDHTSVVCCVKFSNDGEYLATGCNKTTQVYRVSDGSLVARLSDDSAANNHRNSITENNTTTSTDNNTMTTTTTTTITTTAMTSAAELAKDVENLNTSSSPSSDLYIRSVCFSPDGKFLATGAEDRLIRIWDIENRKIVMILQGHEQDIYSLDYFPSGDKLVSGSGDRTVRIWDLRTGQCSLTLSIEDGVTTVAVSPGDGKYIAAGSLDRAVRVWDSETGFLVERLDSENESGTGHKDSVYSVVFTRDGQSVVSGSLDRSVKLWNLQNANNKSDSKTPNSGTCEVTYIGHKDFVLSVATTQNDEYILSGSKDRGVLFWDKKSGNPLLMLQGHRNSVISVAVANGSPLGPEYNVFATGSGDCKARIWKYKKIAPN
SIO_010081: YCR084C
subclass of: SO_0000673
so part of: YCR084C
location: complement(260311..262452)
location: region:260311-262452:-1
so has part: feature:260311-262452:-1:exon

NP_010007.1
type: Protein
SIO_000068: ncbiprotein

S000000680
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:260311-262452:-1:exon

YCR085W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCR085W
so part of: sequence
location: <262916..>263269
location: region:262916-263269:1
so has part: feature:262916-263269:1:exon
subclass of: SO_0000010

850446
type: Gene
SIO_000068: ncbigene

position:262916:1
position: 262916
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:263269:1
position: 263269
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:262916-263269:1:exon

YCR085W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCR085W
product: uncharacterized protein
transcript id: NM_001348897.1
SIO_010081: YCR085W
subclass of: SO_0000673
so part of: YCR085W
location: <262916..>263269
location: region:262916-263269:1
so has part: feature:262916-263269:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:262916-263269:1:exon

YCR085W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YCR085W
note: hypothetical protein; conserved among S. cerevisiae strains; YCR085W is not an essential gene
codon start: 1
product: uncharacterized protein
translation: MLFLYTYVYVFLCTNNDVYNETSVMLSKTSAHCFIAEEVTTDNGLICGLAMLGKTKYQFYELFTVYSIQSLTQLASRVKKGGLIMARLILFTLCALPVLFHFILFMLQYLVFVYIEK
SIO_010081: YCR085W
subclass of: SO_0000673
so part of: YCR085W
location: 262916..263269
location: region:262916-263269:1
so has part: feature:262916-263269:1:exon

NP_001335752.1
type: Protein
SIO_000068: ncbiprotein

S000000681
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:262916-263269:1:exon

YCR086W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CSM1
locus tag: YCR086W
so part of: sequence
location: <263392..>263964
location: region:263392-263964:1
so has part: feature:263392-263964:1:exon
subclass of: SO_0000010

850447
type: Gene
SIO_000068: ncbigene

position:263392:1
position: 263392
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:263964:1
position: 263964
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:263392-263964:1:exon

YCR086W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CSM1
locus tag: YCR086W
product: Csm1p
transcript id: NM_001178792.1
SIO_010081: YCR086W
subclass of: SO_0000673
so part of: YCR086W
location: <263392..>263964
location: region:263392-263964:1
so has part: feature:263392-263964:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:263392-263964:1:exon

YCR086W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CSM1
locus tag: YCR086W
experiment: EXISTENCE:direct assay:GO:0005635 nuclear envelope [PMID:11489916]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:12689592]
experiment: EXISTENCE:direct assay:GO:0033551 monopolin complex [PMID:12689592]
experiment: EXISTENCE:genetic interaction:GO:0051455 monopolar spindle attachment to meiosis I kinetochore [PMID:12689592]
experiment: EXISTENCE:mutant phenotype:GO:0034503 protein localization to nucleolar rDNA repeats [PMID:19362534]
experiment: EXISTENCE:mutant phenotype:GO:0045132 meiotic chromosome segregation [PMID:11470404]
experiment: EXISTENCE:mutant phenotype:GO:0045143 homologous chromosome segregation [PMID:12689592]
experiment: EXISTENCE:mutant phenotype:GO:0070550 rDNA chromatin condensation [PMID:18923139]
experiment: EXISTENCE:physical interaction:GO:0045143 homologous chromosome segregation [PMID:12689592]
note: Nucleolar protein that mediates homolog segregation during meiosis I; forms a complex with Lrs4p and then Mam1p at kinetochores; required for condensin recruitment to the replication fork barrier site and rDNA repeat segregation
codon start: 1
product: Csm1p
translation: MDPLTVYKNSVKQQIDSADLLVANLVNENFVLSEKLDTKATEIKQLQKQIDSLNAQVKELKTQTSQQAENSEVIKDLYEYLCNVRVHKSYEDDSGLWFDISQGTHSGGSSDDYSIMDYKLGFVKGQAQVTEVIYAPVLKQRSTEELYSLQSKLPEYLFETLSFPLSSLNQFYNKIAKSLNKKREKKDETE
SIO_010081: YCR086W
subclass of: SO_0000673
so part of: YCR086W
location: 263392..263964
location: region:263392-263964:1
so has part: feature:263392-263964:1:exon

NP_010009.1
type: Protein
SIO_000068: ncbiprotein

S000000682
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:263392-263964:1:exon

YCR087C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCR087C-A
so part of: sequence
location: complement(<264006..>264467)
location: region:264006-264467:-1
so has part: feature:264006-264467:-1:exon
subclass of: SO_0000010

850449
type: Gene
SIO_000068: ncbigene

position:264006:-1
position: 264006
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:264467:-1
position: 264467
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:264006-264467:-1:exon

YCR087C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCR087C-A
product: uncharacterized protein
transcript id: NM_001184316.1
SIO_010081: YCR087C-A
subclass of: SO_0000673
so part of: YCR087C-A
location: complement(<264006..>264467)
location: region:264006-264467:-1
so has part: feature:264006-264467:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:264006-264467:-1:exon

YCR087C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YCR087C-A
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:14562095]
note: hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus; YCR087C-A is not an essential gene
codon start: 1
product: uncharacterized protein
translation: MVTFNCEVCNDTVPKKNTEKHYYRCPNAYYTCIDCSKTFEDGVSYKNHTSCISEDEKYQKALYKGNKKQKQKQQQKQQQKQHQHQPVATPAKKVEKPVIKKAEKVEKTSNGIELHKGKSLYKILKTMKDKGAKKTFLKSLVVDSEGQIRYAKE
SIO_010081: YCR087C-A
subclass of: SO_0000673
so part of: YCR087C-A
location: complement(264006..264467)
location: region:264006-264467:-1
so has part: feature:264006-264467:-1:exon

NP_010011.1
type: Protein
SIO_000068: ncbiprotein

S000007223
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:264006-264467:-1:exon

YCR088W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ABP1
locus tag: YCR088W
so part of: sequence
location: <265068..>266846
location: region:265068-266846:1
so has part: feature:265068-266846:1:exon
subclass of: SO_0000010

850450
type: Gene
SIO_000068: ncbigene

position:265068:1
position: 265068
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:266846:1
position: 266846
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:265068-266846:1:exon

YCR088W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ABP1
locus tag: YCR088W
product: Abp1p
transcript id: NM_001178794.1
SIO_010081: YCR088W
subclass of: SO_0000673
so part of: YCR088W
location: <265068..>266846
location: region:265068-266846:1
so has part: feature:265068-266846:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:265068-266846:1:exon

YCR088W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ABP1
locus tag: YCR088W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005938 cell cortex [PMID:11950888]
experiment: EXISTENCE:direct assay:GO:0030479 actin cortical patch [PMID:3060468|PMID:8163554|PMID:16824951]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:19053807]
experiment: EXISTENCE:direct assay:GO:0051015 actin filament binding [PMID:3060468]
experiment: EXISTENCE:direct assay:GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation [PMID:16824951]
experiment: EXISTENCE:mutant phenotype:GO:0000147 actin cortical patch assembly [PMID:18177206]
experiment: EXISTENCE:mutant phenotype:GO:0044379 protein localization to actin cortical patch [PMID:10087264|PMID:11668184|PMID:15798181]
experiment: EXISTENCE:mutant phenotype:GO:0051016 barbed-end actin filament capping [PMID:23333351]
note: Actin-binding protein of the cortical actin cytoskeleton; important for activation of actin nucleation mediated by the Arp2/Arp3 complex; inhibits actin filament elongation at the barbed-end; phosphorylation within its proline-rich region, mediated by Cdc28p and Pho85p, protects Abp1p from PEST sequence-mediated proteolysis; mammalian homolog of HIP-55 (hematopoietic progenitor kinase 1 [HPK1]-interacting protein of 55 kDa)
codon start: 1
product: Abp1p
translation: MALEPIDYTTHSREIDAEYLKIVRGSDPDTTWLIISPNAKKEYEPESTGSSFHDFLQLFDETKVQYGLARVSPPGSDVEKIIIIGWCPDSAPLKTRASFAANFAAVANNLFKGYHVQVTARDEDDLDENELLMKISNAAGARYSIQTSSKQQGKASTPPVKKSFTPSKSPAPVSKKEPVKTPSPAPAAKISSRVNDNNDDDDWNEPELKERDFDQAPLKPNQSSYKPIGKIDLQKVIAEEKAKEDPRLVQKPTAAGSKIDPSSDIANLKNESKLKRDSEFNSFLGTTKPPSMTESSLKNDDDKVIKGFRNEKSPAQLWAERKAKQNSGNAETKAEAPKPEVPEDEPEGEPDVKDLKSKFEGLAASEKEEEEMENKFAPPPKKSEPTIISPKPFSKPQEPVKAEEAEQPKTDYKKIGNPLPGMHIEADNEEEPEENDDDWDDDEDEAAQPPLPSRNVASGAPVQKEEPEQEEIAPSLPSRNSIPAPKQEEAPEQAPEEEIEEEAEEAAPQLPSRSSAAPPPPPRRATPEKKPKENPWATAEYDYDAAEDNELTFVENDKIINIEFVDDDWWLGELEKDGSKGLFPSNYVSLGN
SIO_010081: YCR088W
subclass of: SO_0000673
so part of: YCR088W
location: 265068..266846
location: region:265068-266846:1
so has part: feature:265068-266846:1:exon

NP_010012.1
type: Protein
SIO_000068: ncbiprotein

S000000684
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:265068-266846:1:exon

YCR089W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FIG2
locus tag: YCR089W
so part of: sequence
location: <267434..>272263
location: region:267434-272263:1
so has part: feature:267434-272263:1:exon
subclass of: SO_0000010

850451
type: Gene
SIO_000068: ncbigene

position:267434:1
position: 267434
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:272263:1
position: 272263
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:267434-272263:1:exon

YCR089W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FIG2
locus tag: YCR089W
product: Fig2p
transcript id: NM_001178795.1
SIO_010081: YCR089W
subclass of: SO_0000673
so part of: YCR089W
location: <267434..>272263
location: region:267434-272263:1
so has part: feature:267434-272263:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:267434-272263:1:exon

YCR089W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FIG2
locus tag: YCR089W
experiment: EXISTENCE:direct assay:GO:0005937 mating projection [PMID:11027318]
experiment: EXISTENCE:direct assay:GO:0009277 fungal-type cell wall [PMID:9456310]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0000753 cell morphogenesis involved in conjugation with cellular fusion [PMID:9456310]
experiment: EXISTENCE:mutant phenotype:GO:0000755 cytogamy [PMID:9456310]
experiment: EXISTENCE:mutant phenotype:GO:0001403 invasive growth in response to glucose limitation [PMID:11027318]
experiment: EXISTENCE:mutant phenotype:GO:0044182 filamentous growth of a population of unicellular organisms [PMID:11027318]
note: Cell wall adhesin, expressed specifically during mating; may be involved in maintenance of cell wall integrity during mating; FIG2 has a paralog, AGA1, that arose from the whole genome duplication
codon start: 1
product: Fig2p
translation: MNSFASLGLIYSVVNLLTRVEAQIVFYQNSSTSLPVPTLVSTSIADFHESSSTGEVQYSSSYSYVQPSIDSFTSSSFLTSFEAPTETSSSYAVSSSLITSDTFSSYSDIFDEETSSLISTSAASSEKASSTLSSTAQPHRTSHSSSSFELPVTAPSSSSLPSSTSLTFTSVNPSQSWTSFNSEKSSALSSTIDFTSSEISGSTSPKSLESFDTTGTITSSYSPSPSSKNSNQTSLLSPLEPLSSSSGDLILSSTIQATTNDQTSKTIPTLVDATSSLPPTLRSSSMAPTSGSDSISHNFTSPPSKTSGNYDVLTSNSIDPSLFTTTSEYSSTQLSSLNRASKSETVNFTASIASTPFGTDSATSLIDPISSVGSTASSFVGISTANFSTQGNSNYVPESTASGSSQYQDWSSSSLPLSQTTWVVINTTNTQGSVTSTTSPAYVSTATKTVDGVITEYVTWCPLTQTKSQAIGVSSSISSVPQASSFSGSSILSSNSSTLAASNNVPESTASGSSQYQDWSSSSLPLSQTTWVVINTTNTQGSVTSTTSPAYVSTATKTVDGVITEYVTWCPLTQTKSQAIGISSSTISATQTSKPSSILTLGISTLQLSDATFKGTETINTHLMTESTSITEPTYFSGTSDSFYLCTSEVNLASSLSSYPNFSSSEGSTATITNSTVTFGSTSKYPSTSVSNPTEASQHVSSSVNSLTDFTSNSTETIAVISNIHKTSSNKDYSLTTTQLKTSGMQTLVLSTVTTTVNGAATEYTTWCPASSIAYTTSISYKTLVLTTEVCSHSECTPTVITSVTATSSTIPLLSTSSSTVLSSTVSEGAKNPAASEVTINTQVSATSEATSTSTQVSATSATATASESSTTSQVSTASETISTLGTQNFTTTGSLLFPALSTEMINTTVVSRKTLIISTEVCSHSKCVPTVITEVVTSKGTPSNGHSSQTLQTEAVEVTLSSHQTVTMSTEVCSNSICTPTVITSVQMRSTPFPYLTSSTSSSSLASTKKSSLEASSEMSTFSVSTQSLPLAFTSSEKRSTTSVSQWSNTVLTNTIMSSSSNVISTNEKPSSTTSPYNFSSGYSLPSSSTPSQYSLSTATTTINGIKTVYTTWCPLAEKSTVAASSQSSRSVDRFVSSSKPSSSLSQTSIQYTLSTATTTISGLKTVYTTWCPLTSKSTLGATTQTSSTAKVRITSASSATSTSISLSTSTESESSSGYLSKGVCSGTECTQDVPTQSSSPASTLAYSPSVSTSSSSSFSTTTASTLTSTHTSVPLLPSSSSISASSPSSTSLLSTSLPSPAFTSSTLPTATAVSSSTFIASSLPLSSKSSLSLSPVSSSILMSQFSSSSSSSSSLASLPSLSISPTVDTVSVLQPTTSIATLTCTDSQCQQEVSTICNGSNCDDVTSTATTPPSTVTDTMTCTGSECQKTTSSSCDGYSCKVSETYKSSATISACSGEGCQASATSELNSQYVTMTSVITPSAITTTSVEVHSTESTISITTVKPVTYTSSDTNGELITITSSSQTVIPSVTTIITRTKVAITSAPKPTTTTYVEQRLSSSGIATSFVAAASSTWITTPIVSTYAGSASKFLCSKFFMIMVMVINFI
SIO_010081: YCR089W
subclass of: SO_0000673
so part of: YCR089W
location: 267434..272263
location: region:267434-272263:1
so has part: feature:267434-272263:1:exon

NP_010013.2
type: Protein
SIO_000068: ncbiprotein

S000000685
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:267434-272263:1:exon

YCR090C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCR090C
so part of: sequence
location: complement(<272315..>272863)
location: region:272315-272863:-1
so has part: feature:272315-272863:-1:exon
subclass of: SO_0000010

850452
type: Gene
SIO_000068: ncbigene

position:272315:-1
position: 272315
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:272863:-1
position: 272863
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:272315-272863:-1:exon

YCR090C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCR090C
product: uncharacterized protein
transcript id: NM_001178796.1
SIO_010081: YCR090C
subclass of: SO_0000673
so part of: YCR090C
location: complement(<272315..>272863)
location: region:272315-272863:-1
so has part: feature:272315-272863:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:272315-272863:-1:exon

YCR090C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YCR090C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
note: hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YCR090C is not an essential gene
codon start: 1
product: uncharacterized protein
translation: MPLFLVLKATLSENVTKVSIENTNESRAEFAFDLQCTSCRELHDSKVIINTFEEYAMPASKGTASFLMKCKFCSKELSVNLCAFEDEYLTDQSDDKWAKIKDVRKKHGLSKVKEDSFIPLSLDCRGCELIKFYPDTITFEVSLSSGKVMSCQLEDNEWYDYDDNLGEEVTMTDFSSSIIKGK
SIO_010081: YCR090C
subclass of: SO_0000673
so part of: YCR090C
location: complement(272315..272863)
location: region:272315-272863:-1
so has part: feature:272315-272863:-1:exon

NP_010014.1
type: Protein
SIO_000068: ncbiprotein

S000000686
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:272315-272863:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS316; Inefficient autonomously replicating sequence; active in 25% of cell cycles
so part of: sequence
location: 272852..273095
location: region:272852-273095:1
so has part: feature:272852-273095:1:region

S000028491
type: SGD
SIO_000068: sgd

position:272852:1
position: 272852
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:273095:1
position: 273095
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:272852-273095:1:region

YCR091W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: FPK2
gene: KIN82
locus tag: YCR091W
gene synonym: FPK2
so part of: sequence
location: <274404..>276566
location: region:274404-276566:1
so has part: feature:274404-276566:1:exon
subclass of: SO_0000010

850453
type: Gene
SIO_000068: ncbigene

position:274404:1
position: 274404
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:276566:1
position: 276566
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:274404-276566:1:exon

YCR091W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: FPK2
gene: KIN82
locus tag: YCR091W
gene synonym: FPK2
product: putative serine/threonine protein kinase KIN82
transcript id: NM_001178797.2
SIO_010081: YCR091W
subclass of: SO_0000673
so part of: YCR091W
location: <274404..>276566
location: region:274404-276566:1
so has part: feature:274404-276566:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:274404-276566:1:exon

YCR091W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: FPK2
gene: KIN82
locus tag: YCR091W
gene synonym: FPK2
EC number: 2.7.11.1
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:16319894]
experiment: EXISTENCE:genetic interaction:GO:0000749 response to pheromone triggering conjugation with cellular fusion [PMID:25378585]
experiment: EXISTENCE:genetic interaction:GO:0045332 phospholipid translocation [PMID:18199685]
experiment: EXISTENCE:mutant phenotype:GO:0000749 response to pheromone triggering conjugation with cellular fusion [PMID:11337509]
note: Putative serine/threonine protein kinase; implicated in the regulation of phospholipid asymmetry through the activation of phospholipid translocases (flippases); involved in the phosphorylation of upstream inhibitory kinase Ypk1p along with Fpk1p; has a redundant role in the cellular response to mating pheromone; KIN82 has a paralog, FPK1, that arose from the whole genome duplication
codon start: 1
product: putative serine/threonine protein kinase KIN82
translation: MTQQEYRSPSQRLSKGRSMSLPKIFARNLRSLQNNAPPGKNINVNCLNVNSCSLSASPSSQINMACNGNKQDLPIPFPLHVECNDSWSSSKLNKFKSMFNHNRSKSSGTTDASTSEKGTHKREPRSTIHTELLQSSIIGEPNVHSTTSSTLIPNEAICSTPNEISGSSSPDAELFTFDMPTDPSSFHTPSSPSYIAKDSRNLSNGSLNDINENEELQNFHRKISENGSASPLANLSLSNSPIDSPRKNSETRKDQIPMNITPRLRRAASEPFNTAKDGLMREDYIALKQPPSLGDIVEPRRSRRLRTKSFGNKFQDITVEPQSFEKIRLLGQGDVGKVYLVRERDTNQIFALKVLNKHEMIKRKKIKRVLTEQEILATSDHPFIVTLYHSFQTKDYLYLCMEYCMGGEFFRALQTRKSKCIAEEDAKFYASEVVAALEYLHLLGFIYRDLKPENILLHQSGHVMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVIRGNGHTAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILTKDVKFPHDKEVSKNCKDLIKKLLNKNEAKRLGSKSGAADIKRHPFFKKVQWSFLRNQDPPLIPALNDNGCELPFILSCNKHPKRNSVSEQETKMFCEKVANDDEIDEADPFHDFNSMSLTKKDHNILTYSENYTYGKILYKATCTRPRHNSSHRSFFKDIIPEL
SIO_010081: YCR091W
subclass of: SO_0000673
so part of: YCR091W
location: 274404..276566
location: region:274404-276566:1
so has part: feature:274404-276566:1:exon

NP_010015.3
type: Protein
SIO_000068: ncbiprotein

S000000687
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:274404-276566:1:exon

YCR092C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MSH3
locus tag: YCR092C
so part of: sequence
location: complement(<276764..>279820)
location: region:276764-279820:-1
so has part: feature:276764-279820:-1:exon
subclass of: SO_0000010

850454
type: Gene
SIO_000068: ncbigene

position:276764:-1
position: 276764
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:279820:-1
position: 279820
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:276764-279820:-1:exon

YCR092C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MSH3
locus tag: YCR092C
product: mismatch repair protein MSH3
transcript id: NM_001178798.1
SIO_010081: YCR092C
subclass of: SO_0000673
so part of: YCR092C
location: complement(<276764..>279820)
location: region:276764-279820:-1
so has part: feature:276764-279820:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:276764-279820:-1:exon

YCR092C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MSH3
locus tag: YCR092C
experiment: EXISTENCE:direct assay:GO:0000403 Y-form DNA binding [PMID:16781730]
experiment: EXISTENCE:direct assay:GO:0000404 heteroduplex DNA loop binding [PMID:16781730]
experiment: EXISTENCE:direct assay:GO:0000406 double-strand/single-strand DNA junction binding [PMID:16781730]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0030983 mismatched DNA binding [PMID:17636021]
experiment: EXISTENCE:direct assay:GO:0032135 DNA insertion or deletion binding [PMID:8805366]
experiment: EXISTENCE:genetic interaction:GO:0000735 removal of nonhomologous ends [PMID:9256462]
experiment: EXISTENCE:mutant phenotype:GO:0000710 meiotic mismatch repair [PMID:16702432]
experiment: EXISTENCE:mutant phenotype:GO:0000735 removal of nonhomologous ends [PMID:9256462]
experiment: EXISTENCE:mutant phenotype:GO:0006298 mismatch repair [PMID:8510668|PMID:9520271]
experiment: EXISTENCE:mutant phenotype:GO:0006310 DNA recombination [PMID:15920474]
experiment: EXISTENCE:mutant phenotype:GO:0006312 mitotic recombination [PMID:8849883]
experiment: EXISTENCE:mutant phenotype:GO:0043111 replication fork arrest [PMID:27045900]
experiment: EXISTENCE:physical interaction:GO:0032302 MutSbeta complex [PMID:8805366]
note: Mismatch repair protein; forms dimers with Msh2p that mediate repair of insertion or deletion mutations and removal of nonhomologous DNA ends, contains a PCNA (Pol30p) binding motif required for genome stability
codon start: 1
product: mismatch repair protein MSH3
translation: MAGQPTISRFFKKAVKSELTHKQEQEVAVGNGAGSESICLDTDEEDNLSSVASTTVTNDSFPLKGSVSSKNSKNSEKTSGTSTTFNDIDFAKKLDRIMKRRSDENVEAEDDEEEGEEDFVKKKARKSPTAKLTPLDKQVKDLKMHHRDKVLVIRVGYKYKCFAEDAVTVSRILHIKLVPGKLTIDESNPQDCNHRQFAYCSFPDVRLNVHLERLVHHNLKVAVVEQAETSAIKKHDPGASKSSVFERKISNVFTKATFGVNSTFVLRGKRILGDTNSIWALSRDVHQGKVAKYSLISVNLNNGEVVYDEFEEPNLADEKLQIRIKYLQPIEVLVNTDDLPLHVAKFFKDISCPLIHKQEYDLEDHVVQAIKVMNEKIQLSPSLIRLVSKLYSHMVEYNNEQVMLIPSIYSPFASKIHMLLDPNSLQSLDIFTHDGGKGSLFWLLDHTRTSFGLRMLREWILKPLVDVHQIEERLDAIECITSEINNSIFFESLNQMLNHTPDLLRTLNRIMYGTTSRKEVYFYLKQITSFVDHFKMHQSYLSEHFKSSDGRIGKQSPLLFRLFSELNELLSTTQLPHFLTMINVSAVMEKNSDKQVMDFFNLNNYDCSEGIIKIQRESESVRSQLKEELAEIRKYLKRPYLNFRDEVDYLIEVKNSQIKDLPDDWIKVNNTKMVSRFTTPRTQKLTQKLEYYKDLLIRESELQYKEFLNKITAEYTELRKITLNLAQYDCILSLAATSCNVNYVRPTFVNGQQAIIAKNARNPIIESLDVHYVPNDIMMSPENGKINIITGPNMGGKSSYIRQVALLTIMAQIGSFVPAEEIRLSIFENVLTRIGAHDDIINGDSTFKVEMLDILHILKNCNKRSLLLLDEVGRGTGTHDGIAISYALIKYFSELSDCPLILFTTHFPMLGEIKSPLIRNYHMDYVEEQKTGEDWMSVIFLYKLKKGLTYNSYGMNVAKLARLDKDIINRAFSISEELRKESINEDALKLFSSLKRILKSDNITATDKLAKLLSLDIH
SIO_010081: YCR092C
subclass of: SO_0000673
so part of: YCR092C
location: complement(276764..279820)
location: region:276764-279820:-1
so has part: feature:276764-279820:-1:exon

NP_010016.2
type: Protein
SIO_000068: ncbiprotein

S000000688
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:276764-279820:-1:exon

YCR093W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: NOT1
alternative label: ROS1
alternative label: SMD6
gene: CDC39
locus tag: YCR093W
gene synonym: NOT1; ROS1; SMD6
so part of: sequence
location: <280117..>286443
location: region:280117-286443:1
so has part: feature:280117-286443:1:exon
subclass of: SO_0000010

850455
type: Gene
SIO_000068: ncbigene

position:280117:1
position: 280117
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:286443:1
position: 286443
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:280117-286443:1:exon

YCR093W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: NOT1
alternative label: ROS1
alternative label: SMD6
gene: CDC39
locus tag: YCR093W
gene synonym: NOT1; ROS1; SMD6
product: CCR4-NOT core subunit CDC39
transcript id: NM_001178799.1
SIO_010081: YCR093W
subclass of: SO_0000673
so part of: YCR093W
location: <280117..>286443
location: region:280117-286443:1
so has part: feature:280117-286443:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:280117-286443:1:exon

YCR093W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: NOT1
alternative label: ROS1
alternative label: SMD6
gene: CDC39
locus tag: YCR093W
gene synonym: NOT1; ROS1; SMD6
experiment: EXISTENCE:direct assay:GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [PMID:11889048]
experiment: EXISTENCE:direct assay:GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening [PMID:11889048]
experiment: EXISTENCE:direct assay:GO:0001671 ATPase activator activity [PMID:27692063]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:7926748]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11889048]
experiment: EXISTENCE:direct assay:GO:0010607 negative regulation of cytoplasmic mRNA processing body assembly [PMID:27692063]
experiment: EXISTENCE:direct assay:GO:0032968 positive regulation of transcription elongation by RNA polymerase II [PMID:21406554]
experiment: EXISTENCE:genetic interaction:GO:0006368 transcription elongation by RNA polymerase II promoter [PMID:11404327]
experiment: EXISTENCE:mutant phenotype:GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [PMID:11889048]
experiment: EXISTENCE:mutant phenotype:GO:0000749 response to pheromone triggering conjugation with cellular fusion [PMID:2099190]
experiment: EXISTENCE:mutant phenotype:GO:0006368 transcription elongation by RNA polymerase II promoter [PMID:11404327]
experiment: EXISTENCE:mutant phenotype:GO:0007124 pseudohyphal growth [PMID:9055077]
experiment: EXISTENCE:mutant phenotype:GO:0010607 negative regulation of cytoplasmic mRNA processing body assembly [PMID:27692063]
experiment: EXISTENCE:mutant phenotype:GO:0051726 regulation of cell cycle [PMID:2680756]
experiment: EXISTENCE:physical interaction:GO:0006357 regulation of transcription by RNA polymerase II [PMID:10490603]
experiment: EXISTENCE:physical interaction:GO:0030015 CCR4-NOT core complex [PMID:10490603]
note: Subunit of the CCR4-NOT1 core complex; this complex has multiple roles in the regulation of mRNA levels including regulation of transcription and destabilization of mRNA by deadenylation; basal transcription factor that increases initiation and elongation; activates the ATPase activity of Dhh1p, resulting in processing body disassembly
codon start: 1
product: CCR4-NOT core subunit CDC39
translation: MLSATYRDLNTASNLETSKEKQAAQIVIAQISLLFTTLNNDNFESVEREIRHILDRSSVDIYIKVWERLLTLSSRDILQAGKFLLQENLLHRLLLEFAKDLPKKSTDLIELLKERTFNNQEFQKQTGITLSLFIDLFDKSANKDIIESLDRSSQINDFKTIKMNHTNYLRNFFLQTTPETLESNLRDLLHSLEGESLNDLLALLLSEILSPGSQNLQNDPTRSWLTPPMVLDATNRGNVIARSISSLQANQINWNRVFNLMSTKYFLSAPLMPTTASLSCLFAALHDGPVIDEFFSCDWKVIFKLDLAIQLHKWSVQNGCFDLLNAEGTRKVSETIPNTKQSLLYLLSIASLNLELFLQREELSDGPMLAYFQECFFEDFNYAPEYLILALVKEMKRFVLLIENRTVIDEILITLLIQVHNKSPSSFKDVISTITDDSKIVDAAKIIINSDDAPIANFLKSLLDTGRLDTVINKLPFNEAFKILPCARQIGWEGFDTFLKTKVSPSNVDVVLESLEVQTKMTDTNTPFRSLKTFDLFAFHSLIEVLNKCPLDVLQLQRFESLEFSLLIAFPRLINFGFGHDEAILANGDIAGINNDIEKEMQNYLQKMYSGELAIKDVIELLRRLRDSDLPRDQEVFTCITHAVIAESTFFQDYPLDALATTSVLFGSMILFQLLRGFVLDVAFRIIMRFAKEPPESKMFKFAVQAIYAFRIRLAEYPQYCKDLLRDVPALKSQAQVYQSIVEAATLANAPKERSRPVQEMIPLKFFAVDEVSCQINQEGAPKDVVEKVLFVLNNVTLANLNNKVDELKKSLTPNYFSWFSTYLVTQRAKTEPNYHDLYSKVIVAMGSGLLHQFMVNVTLRQLFVLLSTKDEQAIDKKHLKNLASWLGCITLALNKPIKHKNIAFREMLIEAYKENRLEIVVPFVTKILQRASESKIFKPPNPWTVGILKLLIELNEKANWKLSLTFEVEVLLKSFNLTTKSLKPSNFINTPEVIETLSGALGSITLEQQQTEQQRQIILMQQHQQQMLIYQQRQQQQQQRQQQQQHHISANTIADQQAAFGGEGSISHDNPFNNLLGSTIFVTHPDLKRVFQMALAKSVREILLEVVEKSSGIAVVTTTKIILKDFATEVDESKLKTAAIIMVRHLAQSLARATSIEPLKEGIRSTMQSLAPNLMSLSSSPAEELDTAINENIGIALVLIEKASMDKSTQDLADQLMQAIAIRRYHKERRADQPFITQNTNPYSLSLPEPLGLKNTGVTPQQFRVYEEFGKNIPNLDVIPFAGLPAHAPPMTQNVGLTQPQQQQAQMPTQILTSEQIRAQQQQQQLQKSRLNQPSQSAQPPGVNVPNPQGGIAAVQSDLEQNQRVLVHLMDILVSQIKENATKNNLAELGDQNQIKTIIFQILTFIAKSAQKDQLALKVSQAVVNSLFATSESPLCREVLSLLLEKLCSLSLVARKDVVWWLVYALDSRKFNVPVIRSLLEVNLIDATELDNVLVTAMKNKMENSTEFAMKLIQNTVLSDDPILMRMDFIKTLEHLASSEDENVKKFIKEFEDTKIMPVRKGTKTTRTEKLYLVFTEWVKLLQRVENNDVITTVFIKQLVEKGVISDTDNLLTFVKSSLELSVSSFKESDPTDEVFIAIDALGSLIIKLLILQGFKDDTRRDYINAIFSVIVLVFAKDHSQEGTTFNERPYFRLFSNILYEWATIRTHNFVRISDSSTRQELIEFDSVFYNTFSGYLHALQPFAFPGFSFAWVTLLSHRMLLPIMLRLPNKIGWEKLMLLIIDLFKFLDQYTSKHAVSDAVSVVYKGTLRVILGISNDMPSFLIENHYELMNNLPPTYFQLKNVILSAIPKNMTVPNPYDVDLNMEDIPACKELPEVFFDPVIDLHSLKKPVDNYLRIPSNSLLRTILSAIYKDTYDIKKGVGYDFLSVDSKLIRAIVLHVGIEAGIEYKRTSSNAVFNTKSSYYTLLFNLIQNGSIEMKYQIILSIVEQLRYPNIHTY…
SIO_010081: YCR093W
subclass of: SO_0000673
so part of: YCR093W
location: 280117..286443
location: region:280117-286443:1
so has part: feature:280117-286443:1:exon

NP_010017.2
type: Protein
SIO_000068: ncbiprotein

S000000689
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:280117-286443:1:exon

YCR094W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CDC50
locus tag: YCR094W
so part of: sequence
location: <286762..>287937
location: region:286762-287937:1
so has part: feature:286762-287937:1:exon
subclass of: SO_0000010

850456
type: Gene
SIO_000068: ncbigene

position:286762:1
position: 286762
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:287937:1
position: 287937
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:286762-287937:1:exon

YCR094W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CDC50
locus tag: YCR094W
product: aminophospholipid translocase regulatory protein CDC50
transcript id: NM_001178800.1
SIO_010081: YCR094W
subclass of: SO_0000673
so part of: YCR094W
location: <286762..>287937
location: region:286762-287937:1
so has part: feature:286762-287937:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:286762-287937:1:exon

YCR094W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CDC50
locus tag: YCR094W
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005802 trans-Golgi network [PMID:15090616]
experiment: EXISTENCE:direct assay:GO:0031902 late endosome membrane [PMID:12589066]
experiment: EXISTENCE:genetic interaction:GO:0006897 endocytosis [PMID:16195350]
experiment: EXISTENCE:genetic interaction:GO:0015247 aminophospholipid flippase activity [PMID:15090616]
experiment: EXISTENCE:genetic interaction:GO:0045332 phospholipid translocation [PMID:15090616]
experiment: EXISTENCE:genetic interaction:GO:0051666 actin cortical patch localization [PMID:16195350]
experiment: EXISTENCE:mutant phenotype:GO:0006886 intracellular protein transport [PMID:16956384]
experiment: EXISTENCE:mutant phenotype:GO:0042147 retrograde transport, endosome to Golgi [PMID:28057802]
experiment: EXISTENCE:physical interaction:GO:1990530 Cdc50p-Drs2p complex [PMID:15090616]
note: Endosomal protein that interacts with phospholipid flippase Drs2p; interaction with Cdc50p is essential for Drs2p catalytic activity; mutations affect cell polarity and polarized growth; similar to Lem3p; CDC50 has a paralog, YNR048W, that arose from the whole genome duplication
codon start: 1
product: aminophospholipid translocase regulatory protein CDC50
translation: MVSLFKRGKAPPLTKEGPTSKKPPNTAFRQQRLKAWQPILSPQSVLPLLIFVACIFTPIGIGLIVSATKVQDLTIDYSHCDTKASTTAFEDIPKKYIKYHFKSKVENKPQWRLTENENGEQSCELQFEIPNDIKKSIFIYYKITNFYQNHRRYVQSFDTKQILGEPIKKDDLDTSCSPIRSREDKIIYPCGLIANSMFNDTFSQVLSGIDDTEDYNLTNKHISWSIDRHRFKTTKYNASDIVPPPNWMKKYPDGYTDENLPDIHTWEEFQVWMRTAAFPKFYKLTLKNESASLPKGKYQMNIELNYPISLFGGTKSFVLTTNGAIGGRNMSLGVLYLIVAGLCALFGIIFLVKLIFQPRAMGDHTYLNFDDEENEDYEDVHAENTTLREIL
SIO_010081: YCR094W
subclass of: SO_0000673
so part of: YCR094W
location: 286762..287937
location: region:286762-287937:1
so has part: feature:286762-287937:1:exon

NP_010018.1
type: Protein
SIO_000068: ncbiprotein

S000000690
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:286762-287937:1:exon

YCR095C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: OCA4
locus tag: YCR095C
so part of: sequence
location: complement(<288170..>289258)
location: region:288170-289258:-1
so has part: feature:288170-289258:-1:exon
subclass of: SO_0000010

850457
type: Gene
SIO_000068: ncbigene

position:288170:-1
position: 288170
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:289258:-1
position: 289258
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:288170-289258:-1:exon

YCR095C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: OCA4
locus tag: YCR095C
product: Oca4p
transcript id: NM_001178801.1
SIO_010081: YCR095C
subclass of: SO_0000673
so part of: YCR095C
location: complement(<288170..>289258)
location: region:288170-289258:-1
so has part: feature:288170-289258:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:288170-289258:-1:exon

YCR095C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: OCA4
locus tag: YCR095C
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
note: Cytoplasmic protein required for replication of Brome mosaic virus; S. cerevisiae is a model system for studying replication of positive-strand RNA viruses in their natural hosts
codon start: 1
product: Oca4p
translation: MLVPPANFGIAEEGIYRCSKVETLNLSFLETLNLKTAIFIGGQEPSKFFKDFFTRSSIKWIVLRMSDFSAAAVPVKSSSVSNANLYSNNNSTLSLQEEKKKSTANGSQNSTTGDPVIQEELAYHLTDNDDLMLIKSTCLKRTFKTLLNVDNYNVLLVDKTALVIGILRKIQKWNIASIINEYRLFSGKNRNYFAETFLEIINIEIEQEKDNKTIVDNKAKKLPLENNRTHSIEYKANSGKLIRVNEDDLCREPEVPQRLLTLINQIETKVKNNKVLQVSGVLGDDLKKTSSDLGIFGHRYRLAFNKKENGDYGYYKARGKDNVKIRIPCDSELPDWFRFQRDLWEKENVPEEHHFYREHIFT
SIO_010081: YCR095C
subclass of: SO_0000673
so part of: YCR095C
location: complement(288170..289258)
location: region:288170-289258:-1
so has part: feature:288170-289258:-1:exon

NP_010019.1
type: Protein
SIO_000068: ncbiprotein

S000000691
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:288170-289258:-1:exon

YCR095W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCR095W-A
so part of: sequence
location: <289639..>289797
location: region:289639-289797:1
so has part: feature:289639-289797:1:exon
subclass of: SO_0000010

3077354
type: Gene
SIO_000068: ncbigene

position:289639:1
position: 289639
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:289797:1
position: 289797
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:289639-289797:1:exon

YCR095W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCR095W-A
product: uncharacterized protein
transcript id: NM_001184674.1
SIO_010081: YCR095W-A
subclass of: SO_0000673
so part of: YCR095W-A
location: <289639..>289797
location: region:289639-289797:1
so has part: feature:289639-289797:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:289639-289797:1:exon

YCR095W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YCR095W-A
codon start: 1
product: uncharacterized protein
translation: MTVLIKLGLRILHVYKGFFRKVILKYFFFSSEHTKVNKKSSMHAFLCKIYKR
SIO_010081: YCR095W-A
subclass of: SO_0000673
so part of: YCR095W-A
location: 289639..289797
location: region:289639-289797:1
so has part: feature:289639-289797:1:exon

NP_001018032.1
type: Protein
SIO_000068: ncbiprotein

S000029724
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:289639-289797:1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 291373..291712
location: region:291373-291712:1
so has part: feature:291373-291712:1:region

S000006839
type: SGD
SIO_000068: sgd

position:291373:1
position: 291373
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:291712:1
position: 291712
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:291373-291712:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty5 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 291922..292167
location: region:291922-292167:1
so has part: feature:291922-292167:1:region

S000006841
type: SGD
SIO_000068: sgd

position:291922:1
position: 291922
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:292167:1
position: 292167
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:291922-292167:1:region

misc_feature
type: Miscellaneous Feature
subclass of: SO_0000001
RO_0002162: 559292
note: HMR; Mating-type cassette - right; unexpressed complete copy of the mating-type genes, silenced by the Sir2 histone deacetylase and its associated SIR1, SIR3 and SIR4 proteins; mating-type switching involves replacement of the Ya or Yalpha sequences present at the MAT locus with either the a or alpha genes located at one of the HM loci in a process stimulated by the HO endonuclease; sequence replacement occurs by gene conversion, leaving the donor unaltered
so part of: sequence
location: 292388..295034
location: region:292388-295034:1
so has part: feature:292388-295034:1:region

S000029655
type: SGD
SIO_000068: sgd

position:292388:1
position: 292388
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:295034:1
position: 295034
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:292388-295034:1:region

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS317; ARS that fires extremely inefficiently and late during S phase; fires late and inefficiently compared to other origins in the genome; active in only a small fraction of cell cycles
so part of: sequence
location: 292638..292694
location: region:292638-292694:1
so has part: feature:292638-292694:1:region

S000028492
type: SGD
SIO_000068: sgd

position:292638:1
position: 292638
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:292694:1
position: 292694
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:292638-292694:1:region

YCR096C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: A2
gene: HMRA2
locus tag: YCR096C
gene synonym: A2
so part of: sequence
location: complement(<293179..>293538)
location: region:293179-293538:-1
so has part: feature:293179-293538:-1:exon
subclass of: SO_0000010

850458
type: Gene
SIO_000068: ncbigene

position:293179:-1
position: 293179
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:293538:-1
position: 293538
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:293179-293538:-1:exon

YCR096C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: A2
gene: HMRA2
locus tag: YCR096C
gene synonym: A2
product: homeodomain mating type protein a2
transcript id: NM_001178802.1
SIO_010081: YCR096C
subclass of: SO_0000673
so part of: YCR096C
location: complement(<293179..>293538)
location: region:293179-293538:-1
so has part: feature:293179-293538:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:293179-293538:-1:exon

YCR096C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: A2
gene: HMRA2
locus tag: YCR096C
gene synonym: A2
note: Silenced copy of a2 at HMR; similarity to Alpha2p; required along with a1p for inhibiting expression of the HO endonuclease in a/alpha HO/HO diploid cells with an active mating-type interconversion system
codon start: 1
product: homeodomain mating type protein a2
translation: MRSIENDRSNYQLTQKNKSADGLVFNVVTQDMINKSTKPYRGHRFTKENVRILESWFAKNIENPYLDTKGLENLMKNTSLSRIQIKNWVSNRRRKEKTITIAPELADLLSGEPLAKKKE
SIO_010081: YCR096C
subclass of: SO_0000673
so part of: YCR096C
location: complement(293179..293538)
location: region:293179-293538:-1
so has part: feature:293179-293538:-1:exon

NP_010020.1
type: Protein
SIO_000068: ncbiprotein

S000000692
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:293179-293538:-1:exon

YCR097W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YCR097WB
gene: HMRA1
locus tag: YCR097W
gene synonym: YCR097WB
so part of: sequence
location: <293835..>294321
location: region:293835-294321:1
so has part: feature:293835-294321:1:exon
subclass of: SO_0000010

850459
type: Gene
SIO_000068: ncbigene

position:293835:1
position: 293835
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:294321:1
position: 294321
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:293835-294321:1:exon

YCR097W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YCR097WB
gene: HMRA1
locus tag: YCR097W
gene synonym: YCR097WB
product: Hmra1p
transcript id: NM_001178804.1
SIO_010081: YCR097W
subclass of: SO_0000673
so part of: YCR097W
location: join(<293835..293939,293994..294239,294292..>294321)
location: region:293835-294321:1
so has part: feature:293835-293939:1:exon
so has part: feature:293994-294239:1:exon
so has part: feature:294292-294321:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:293835-293939:1:exon

position:293939:1
position: 293939
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:293994-294239:1:exon

position:293994:1
position: 293994
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:294239:1
position: 294239
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 3
SIO_000628: feature:294292-294321:1:exon

position:294292:1
position: 294292
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YCR097W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YCR097WB
gene: HMRA1
locus tag: YCR097W
gene synonym: YCR097WB
experiment: EXISTENCE:direct assay:GO:0003714 transcription corepressor activity [PMID:1977088]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:8411150]
experiment: EXISTENCE:direct assay:GO:0007532 regulation of mating-type specific transcription, DNA-templated [PMID:1977088]
note: Silenced copy of a1 at HMR; homeobox corepressor that interacts with Alpha2p to repress haploid-specific gene transcription in diploid cells
codon start: 1
product: Hmra1p
translation: MDDICSMAENINRTLFNILGTEIDEINLNTNNLYNFIMESNLTKVEQHTLHKNISNNRLEIYHHIKKEKSPKGKSSISPQARAFLEQVFRRKQSLNSKEKEEVAKKCGITPLQVRVWFINKRMRSK
SIO_010081: YCR097W
subclass of: SO_0000673
so part of: YCR097W
location: join(293835..293939,293994..294239,294292..294321)
location: region:293835-294321:1
so has part: feature:293835-293939:1:exon
so has part: feature:293994-294239:1:exon
so has part: feature:294292-294321:1:exon

NP_010021.1
type: Protein
SIO_000068: ncbiprotein

S000000694
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:293835-293939:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:293994-294239:1:exon

urn:…
SIO_000300: 3
SIO_000628: feature:294292-294321:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS318; ARS that becomes active if the nearby ARS317/HMR-E silencer is deleted; active in only a small fraction of cell cycles
so part of: sequence
location: 294820..294901
location: region:294820-294901:1
so has part: feature:294820-294901:1:region

S000028493
type: SGD
SIO_000068: sgd

position:294820:1
position: 294820
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:294901:1
position: 294901
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:294820-294901:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 295003..295330
location: region:295003-295330:1
so has part: feature:295003-295330:1:region

S000006840
type: SGD
SIO_000068: sgd

position:295003:1
position: 295003
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:295330:1
position: 295330
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:295003-295330:1:region

YNCC0014W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCC0014W
so part of: sequence
location: 295484..295556
location: region:295484-295556:1
so has part: feature:295484-295556:1:exon
subclass of: SO_0000663

850461
type: Gene
SIO_000068: ncbigene

position:295484:1
position: 295484
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:295556:1
position: 295556
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:295484-295556:1:exon

YNCC0014W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCC0014W
product: tRNA-Thr
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Threonine tRNA (tRNA-Thr), predicted by tRNAscan-SE analysis
SIO_010081: YNCC0014W
subclass of: SO_0000673
so part of: YNCC0014W
location: 295484..295556
location: region:295484-295556:1
so has part: feature:295484-295556:1:exon

S000006738
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:295484-295556:1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(295958..296190)
location: region:295958-296190:-1
so has part: feature:295958-296190:-1:region

S000006834
type: SGD
SIO_000068: sgd

position:295958:-1
position: 295958
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:296190:-1
position: 296190
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:295958-296190:-1:region

YCR098C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GIT1
locus tag: YCR098C
so part of: sequence
location: complement(<297049..>298605)
location: region:297049-298605:-1
so has part: feature:297049-298605:-1:exon
subclass of: SO_0000010

850462
type: Gene
SIO_000068: ncbigene

position:297049:-1
position: 297049
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:298605:-1
position: 298605
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:297049-298605:-1:exon

YCR098C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GIT1
locus tag: YCR098C
product: Git1p
transcript id: NM_001178805.1
SIO_010081: YCR098C
subclass of: SO_0000673
so part of: YCR098C
location: complement(<297049..>298605)
location: region:297049-298605:-1
so has part: feature:297049-298605:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:297049-298605:-1:exon

YCR098C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GIT1
locus tag: YCR098C
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0001406 glycerophosphodiester transmembrane transporter activity [PMID:16924500]
experiment: EXISTENCE:direct assay:GO:0001407 glycerophosphodiester transmembrane transport [PMID:16924500]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:16924500]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0015169 glycerol-3-phosphate transmembrane transporter activity [PMID:20133652]
experiment: EXISTENCE:genetic interaction:GO:0015794 glycerol-3-phosphate transmembrane transport [PMID:20133652]
experiment: EXISTENCE:mutant phenotype:GO:0001406 glycerophosphodiester transmembrane transporter activity [PMID:9691030]
experiment: EXISTENCE:mutant phenotype:GO:0001407 glycerophosphodiester transmembrane transport [PMID:9691030]
experiment: EXISTENCE:mutant phenotype:GO:0005886 plasma membrane [PMID:9691030]
experiment: EXISTENCE:mutant phenotype:GO:0015169 glycerol-3-phosphate transmembrane transporter activity [PMID:20133652]
experiment: EXISTENCE:mutant phenotype:GO:0015794 glycerol-3-phosphate transmembrane transport [PMID:20133652]
experiment: EXISTENCE:mutant phenotype:GO:0055085 transmembrane transport [PMID:9691030]
note: Plasma membrane permease; mediates uptake of glycerophosphoinositol and glycerophosphocholine as sources of the nutrients inositol and phosphate; expression and transport rate are regulated by phosphate and inositol availability
codon start: 1
product: Git1p
translation: MEDKDITSVNEKEVNENTNPRIIKYDAERRATRTETSKKDKWKNIVTIIASGFALISDGYVNGSMSMLNKVFVMEYGKKNYSSKVSTRVSNAALVGIIFGQFFMGIAADYYSRKSCILVATAILVIGSALCAASHGTTVPGMFWMLTVMRGLVGIGVGAEYPTSTLSANESANEYTTTKRGGILVMVTNLPLAFGGPFATIIFLIVYKICSGTKHLEAIWRTVFAIGCFWPLSVFYFRWKTATTEVYEKGRIKRNIPYFLALKFYWKRLLGTCGTWFMYDFVTFPNGIFSSTIISSVIKDQNDLVKVAEWNLLLGVLAVLGVPIGAYLSDRIGRKYTLMFGFSGYIIFGLIIGCAYDQLKKITPLFIIFYAFMNMLGNAGPGDMLGVISSEASATAVRGVFYGLSAVTGKIGSVVGVECFQPIRDNLGARWTFIIAAICGLIGIIITYFFVPHSLESDLMKQDVEFHNYLVSNGWTGKMGFDETDEESMVRTIEVEENGTNCSKKNAEIISVRQVDQS
SIO_010081: YCR098C
subclass of: SO_0000673
so part of: YCR098C
location: complement(297049..298605)
location: region:297049-298605:-1
so has part: feature:297049-298605:-1:exon

NP_010022.1
type: Protein
SIO_000068: ncbiprotein

S000000695
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:297049-298605:-1:exon

YCR099C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCR099C
so part of: sequence
location: complement(<300832..>301299)
location: region:300832-301299:-1
so has part: feature:300832-301299:-1:exon
subclass of: SO_0000010

850463
type: Gene
SIO_000068: ncbigene

position:300832:-1
position: 300832
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:301299:-1
position: 301299
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:300832-301299:-1:exon

YCR099C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCR099C
product: uncharacterized protein
transcript id: NM_001178806.1
SIO_010081: YCR099C
subclass of: SO_0000673
so part of: YCR099C
location: complement(<300832..>301299)
location: region:300832-301299:-1
so has part: feature:300832-301299:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:300832-301299:-1:exon

YCR099C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YCR099C
codon start: 1
product: uncharacterized protein
translation: MRSIFLLHFDYKTCEEEDFEDWNLADGKCLNGAKYMYKRRKQDARCLVKRTFKDMILHEIPCDSCTESDYECSSEFVRDAKGDCIPDYDQIALSDICDKANGETVSLEPLQLIKGDKCKKPMEIEAMNIPCEKILRESSNGKKIATIENKFDFEI
SIO_010081: YCR099C
subclass of: SO_0000673
so part of: YCR099C
location: complement(300832..301299)
location: region:300832-301299:-1
so has part: feature:300832-301299:-1:exon

NP_010023.1
type: Protein
SIO_000068: ncbiprotein

S000000696
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:300832-301299:-1:exon

YCR100C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: EMA35
locus tag: YCR100C
so part of: sequence
location: complement(<301271..>302221)
location: region:301271-302221:-1
so has part: feature:301271-302221:-1:exon
subclass of: SO_0000010

850464
type: Gene
SIO_000068: ncbigene

position:301271:-1
position: 301271
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:302221:-1
position: 302221
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:301271-302221:-1:exon

YCR100C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: EMA35
locus tag: YCR100C
product: Ema35p
transcript id: NM_001178807.1
SIO_010081: YCR100C
subclass of: SO_0000673
so part of: YCR100C
location: complement(<301271..>302221)
location: region:301271-302221:-1
so has part: feature:301271-302221:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:301271-302221:-1:exon

YCR100C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: EMA35
locus tag: YCR100C
note: Protein involved in protein sorting; involved in targeting mitochondrial membrane proteins to mitochondrial translocation system; mutation causes respiration defects
codon start: 1
product: Ema35p
translation: MSSTDIWISNDASTFQKAQLPTQLRHVKVIKIREDSIGRIILLISTEITNEENADPDLSEIFISDSQGLKFSPVEWTPNHQFGNFRLTFPDFLKGTIFGSFHPSIDYSNHQVNYTENIAGGETKISVDNGLTWSNLKVVDEENADSFGCDITRPERCSLQGYFYNLKLSNPSAGIILMTGSVGDDNEFDRKDRKTFISRDGGLTWRVAHNSSGLYATGDLGNIIVYIPSPSYKDGDVQSKLYFSLDQGRTWNQYELVDALFYIHPLELINTTPDGSGSKFILSGHLITTASQEGNNTNISYIARSVLYAIDFSAAF
SIO_010081: YCR100C
subclass of: SO_0000673
so part of: YCR100C
location: complement(301271..302221)
location: region:301271-302221:-1
so has part: feature:301271-302221:-1:exon

NP_010024.1
type: Protein
SIO_000068: ncbiprotein

S000000697
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:301271-302221:-1:exon

YCR101C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCR101C
so part of: sequence
location: complement(<302482..>303030)
location: region:302482-303030:-1
so has part: feature:302482-303030:-1:exon
subclass of: SO_0000010

850465
type: Gene
SIO_000068: ncbigene

position:302482:-1
position: 302482
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:303030:-1
position: 303030
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:302482-303030:-1:exon

YCR101C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCR101C
product: uncharacterized protein
transcript id: NM_001178808.1
SIO_010081: YCR101C
subclass of: SO_0000673
so part of: YCR101C
location: complement(<302482..>303030)
location: region:302482-303030:-1
so has part: feature:302482-303030:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:302482-303030:-1:exon

YCR101C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YCR101C
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0016020 membrane [PMID:11935221]
note: hypothetical protein; localizes to the membrane fraction; YCR101C is not an essential gene
codon start: 1
product: uncharacterized protein
translation: MILLHAIYTLWVIILLPLLNAEKFVPKVTEAPIETSFNLVSFDDSNTSIRLDGWGVVWISFDAGENWETVKEIEERIFRFTVDPFHGQERGFAFICESPKFYITDDRGESWRALTIPSSEEYLDGDCFITTHPRNKELLIANCYSYMIDADVLYDPSEIYLSNDGNPFLKLNLPWKRKKTTI
SIO_010081: YCR101C
subclass of: SO_0000673
so part of: YCR101C
location: complement(302482..303030)
location: region:302482-303030:-1
so has part: feature:302482-303030:-1:exon

NP_010025.1
type: Protein
SIO_000068: ncbiprotein

S000000698
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:302482-303030:-1:exon

YCR102C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCR102C
so part of: sequence
location: complement(<304361..>305467)
location: region:304361-305467:-1
so has part: feature:304361-305467:-1:exon
subclass of: SO_0000010

850466
type: Gene
SIO_000068: ncbigene

position:304361:-1
position: 304361
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:305467:-1
position: 305467
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:304361-305467:-1:exon

YCR102C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCR102C
product: uncharacterized protein
transcript id: NM_001178809.1
SIO_010081: YCR102C
subclass of: SO_0000673
so part of: YCR102C
location: complement(<304361..>305467)
location: region:304361-305467:-1
so has part: feature:304361-305467:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:304361-305467:-1:exon

YCR102C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YCR102C
experiment: EXISTENCE:direct assay:GO:0071468 cellular response to acidic pH [PMID:31374572]
experiment: EXISTENCE:mutant phenotype:GO:0046688 response to copper ion [PMID:15886332]
note: Putative quinone oxidoreductase; overexpression improves ethanol production and acid stress resistance; involved in copper metabolism; similar to Cochliobolus carbonum toxD gene
codon start: 1
product: uncharacterized protein
translation: MKAVVIEDGKAVVKEGVPIPELEEGFVLIKTLAVAGNPTDWAHIDYKVGPQGSILGCDAAGQIVKLGPAVDPKDFSIGDYIYGFIHGSSVRFPSNGAFAEYSAISTVVAYKSPNELKFLGEDVLPAGPVRSLEGAATIPVSLTTAGLVLTYNLGLNLKWEPSTPQRNGPILLWGGATAVGQSLIQLANKLNGFTKIIVVASRKHEKLLKEYGADQLFDYHDIDVVEQIKHKYNNISYLVDCVANQNTLQQVYKCAADKQDATVVELTNLTEENVKKENRRQNVTIDRTRLYSIGGHEVPFGGITFPADPEARRAATEFVKFINPKISDGQIHHIPARVYKNGLYDVPRILEDIKIGKNSGEKLVAVLN
SIO_010081: YCR102C
subclass of: SO_0000673
so part of: YCR102C
location: complement(304361..305467)
location: region:304361-305467:-1
so has part: feature:304361-305467:-1:exon

NP_010026.1
type: Protein
SIO_000068: ncbiprotein

S000000699
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:304361-305467:-1:exon

YCR104W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PAU3
locus tag: YCR104W
so part of: sequence
location: <307801..>308175
location: region:307801-308175:1
so has part: feature:307801-308175:1:exon
subclass of: SO_0000010

850468
type: Gene
SIO_000068: ncbigene

position:307801:1
position: 307801
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:308175:1
position: 308175
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:307801-308175:1:exon

YCR104W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PAU3
locus tag: YCR104W
product: seripauperin PAU3
transcript id: NM_001178811.1
SIO_010081: YCR104W
subclass of: SO_0000673
so part of: YCR104W
location: <307801..>308175
location: region:307801-308175:1
so has part: feature:307801-308175:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:307801-308175:1:exon

YCR104W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PAU3
locus tag: YCR104W
note: Member of the seripauperin multigene family; encoded mainly in subtelomeric region; active during alcoholic fermentation; regulated by anaerobiosis; negatively regulated by oxygen; repressed by heme
codon start: 1
product: seripauperin PAU3
translation: MVKLTSIAAGVAAIAAGIAAAPATTTLSPSDERVNLVELGVYVSDIRAHLAQYYLFQAAHPTETYPVEIAEAVFNYGDFTTMLTGIPAEQVTRVITGVPWYSTRLRPAISSALSKDGIYTAIPK
SIO_010081: YCR104W
subclass of: SO_0000673
so part of: YCR104W
location: 307801..308175
location: region:307801-308175:1
so has part: feature:307801-308175:1:exon

NP_010029.1
type: Protein
SIO_000068: ncbiprotein

S000000701
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:307801-308175:1:exon

YCR105W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ADHVII
gene: ADH7
locus tag: YCR105W
gene synonym: ADHVII
so part of: sequence
location: <309070..>310155
location: region:309070-310155:1
so has part: feature:309070-310155:1:exon
subclass of: SO_0000010

850469
type: Gene
SIO_000068: ncbigene

position:309070:1
position: 309070
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:310155:1
position: 310155
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:309070-310155:1:exon

YCR105W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ADHVII
gene: ADH7
locus tag: YCR105W
gene synonym: ADHVII
product: NADP-dependent alcohol dehydrogenase
transcript id: NM_001178812.1
SIO_010081: YCR105W
subclass of: SO_0000673
so part of: YCR105W
location: <309070..>310155
location: region:309070-310155:1
so has part: feature:309070-310155:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:309070-310155:1:exon

YCR105W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ADHVII
gene: ADH7
locus tag: YCR105W
gene synonym: ADHVII
EC number: 1.1.1.2
experiment: EXISTENCE:direct assay:GO:0006066 alcohol metabolic process [PMID:12423374]
experiment: EXISTENCE:direct assay:GO:0008106 alcohol dehydrogenase (NADP+) activity [PMID:12423374]
note: NADPH-dependent medium chain alcohol dehydrogenase; has broad substrate specificity; member of the cinnamyl family of alcohol dehydrogenases; may be involved in fusel alcohol synthesis or in aldehyde tolerance
codon start: 1
product: NADP-dependent alcohol dehydrogenase
translation: MLYPEKFQGIGISNAKDWKHPKLVSFDPKPFGDHDVDVEIEACGICGSDFHIAVGNWGPVPENQILGHEIIGRVVKVGSKCHTGVKIGDRVGVGAQALACFECERCKSDNEQYCTNDHVLTMWTPYKDGYISQGGFASHVRLHEHFAIQIPENIPSPLAAPLLCGGITVFSPLLRNGCGPGKRVGIVGIGGIGHMGILLAKAMGAEVYAFSRGHSKREDSMKLGADHYIAMLEDKGWTEQYSNALDLLVVCSSSLSKVNFDSIVKIMKIGGSIVSIAAPEVNEKLVLKPLGLMGVSISSSAIGSRKEIEQLLKLVSEKNVKIWVEKLPISEEGVSHAFTRMESGDVKYRFTLVDYDKKFHK
SIO_010081: YCR105W
subclass of: SO_0000673
so part of: YCR105W
location: 309070..310155
location: region:309070-310155:1
so has part: feature:309070-310155:1:exon

NP_010030.1
type: Protein
SIO_000068: ncbiprotein

S000000702
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:309070-310155:1:exon

YCR106W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RDS1
locus tag: YCR106W
so part of: sequence
location: <310958..>313456
location: region:310958-313456:1
so has part: feature:310958-313456:1:exon
subclass of: SO_0000010

850470
type: Gene
SIO_000068: ncbigene

position:310958:1
position: 310958
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:313456:1
position: 313456
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:310958-313456:1:exon

YCR106W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RDS1
locus tag: YCR106W
product: Rds1p
transcript id: NM_001178813.1
SIO_010081: YCR106W
subclass of: SO_0000673
so part of: YCR106W
location: <310958..>313456
location: region:310958-313456:1
so has part: feature:310958-313456:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:310958-313456:1:exon

YCR106W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RDS1
locus tag: YCR106W
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:19111667]
experiment: EXISTENCE:mutant phenotype:GO:0009410 response to xenobiotic stimulus [PMID:11943786]
note: Putative zinc cluster transcription factor; involved in conferring resistance to cycloheximide
codon start: 1
product: Rds1p
translation: MDSITVKKPRLRLVCLQCKKIKRKCDKLRPACSRCQQNSLQCEYEERTDLSANVAANDSDGFNSSHKLNFEQQPVLERTGLRYSLQVPEGVVNATLSIWNAEDMLVIVGLVTFLDYPFAAHSLAQHDQYIRALCASLYGMALVDFSNYANGIPCEDTSRSILGPLSFIEKAIFRRIEHSKQFRVQSAALGLLYNAFSMEEENFSTLLPSLIAEVEDVLMQKKDCEILLRCFYQNIYPFYPFMDISLFESDLTSLLLQDDNNRWKISTEVKNVRKKIETLSLLTIVMAMALMHSKLDANLLSMVKENASESARKLSLLCHKLLCLLDVFRYPNENTFTCLLYFYVSEHLDPESPDCVLSPTNLLTLHHLLNLSMTLGLQYEPSKYKRFKDPEVIRQRRILWLGVQSLLFQISLAEGDAGKSNSEYMEAYLTDFEEYIEASSEYEKSSASESNVQMNDIVWNKYKFHVILSKLMSDCTSVIQHPQLFHILGNIKRSEDFMAENFPTSSIYQPLHEKEPNAIKVGKSTVLDVMDIQKTEIFLTNIVGSMCFLNIFDVLSLHFEKKCVMHWEEYEKNYHFLTLKSFNAYLKLAGLISDYLENKFQGNILESRGYIIDKQICFMLVRIWMFQCRILLRFSYKQESQKKLASSSISTNDNEKEDEMIVILERLIKHIRNQMAHLVDLAKGKLQDSYFGAYQTVPMFRYVVYLIDVGGLVSVTNGFWDKISSDGEIPPKVQQAVRLKWGLDCNNSRRIKQKLISSQSLQSFNQVLLCQMEDAVLSSSFAIKANTAMSQNTAEEFFNISEEEALNQLLENNNFDAFWDLLGENLSDMPSL
SIO_010081: YCR106W
subclass of: SO_0000673
so part of: YCR106W
location: 310958..313456
location: region:310958-313456:1
so has part: feature:310958-313456:1:exon

NP_010031.1
type: Protein
SIO_000068: ncbiprotein

S000000703
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:310958-313456:1:exon

YCR107W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: AAD3
locus tag: YCR107W
so part of: sequence
location: <313890..>314981
location: region:313890-314981:1
so has part: feature:313890-314981:1:exon
subclass of: SO_0000010

850471
type: Gene
SIO_000068: ncbigene

position:313890:1
position: 313890
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:314981:1
position: 314981
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:313890-314981:1:exon

YCR107W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: AAD3
locus tag: YCR107W
product: putative aryl-alcohol dehydrogenase
transcript id: NM_001178814.1
SIO_010081: YCR107W
subclass of: SO_0000673
so part of: YCR107W
location: <313890..>314981
location: region:313890-314981:1
so has part: feature:313890-314981:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:313890-314981:1:exon

YCR107W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: AAD3
locus tag: YCR107W
note: Putative aryl-alcohol dehydrogenase; similar to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role; AAD3 has a paralog, AAD15, that arose from a segmental duplication; members of the AAD gene family comprise three pairs (AAD3 + AAD15, AAD6/AAD16 + AAD4, AAD10 + AAD14) whose two genes are more related to one another than to other members of the family
codon start: 1
product: putative aryl-alcohol dehydrogenase
translation: MIGSASDSSSKLGRLRFLSETAAIKVSPLILGEVSYDGARSDFLKSMNKNRAFELLDTFYEAGGNFIDAANNCQNEQSEEWIGEWIQSRRLRDQIVIATKFIKSDKKYKAGESNTANYCGNHKRSLHVSVRDSLRKLQTDWIDILYVHWWDYMSSIEEFMDSLHILVQQGKVLYLGVSDTPAWVVSAANYYATSYGKTPFSIYQGKWNVLNRDFERDIIPMARHFGMALAPWDVMGGGRFQSKKAMEERRKNGEGIRSFVGASEQTDAEIKISEALAKIAEEHGTESVTAIAIAYVRSKAKNFFPSVEGGKIEDLKENIKALSIDLTPDNIKYLESIVPFDIGFPNNFIVLNSLTQKYGTNNV
SIO_010081: YCR107W
subclass of: SO_0000673
so part of: YCR107W
location: 313890..314981
location: region:313890-314981:1
so has part: feature:313890-314981:1:exon

NP_010032.1
type: Protein
SIO_000068: ncbiprotein

S000000704
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:313890-314981:1:exon

telomere
type: Telomere
subclass of: SO_0000624
RO_0002162: 559292
note: TEL03R; Telomeric region on the right arm of Chromosome III; composed of an X element core sequence, X element combinatorial repeats, and a short terminal stretch of telomeric repeats
so part of: sequence
location: 315783..316620
location: region:315783-316620:1
so has part: feature:315783-316620:1:region

S000028944
type: SGD
SIO_000068: sgd

position:315783:1
position: 315783
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:315783-316620:1:region

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS319; Highly-active subtelomeric autonomously replicating sequence; initiates replication in 90% of cell cycles
so part of: sequence
location: 315807..315879
location: region:315807-315879:1
so has part: feature:315807-315879:1:region

S000028494
type: SGD
SIO_000068: sgd

position:315807:1
position: 315807
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:315879:1
position: 315879
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:315807-315879:1:region

YCR108C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YCR108C
so part of: sequence
location: complement(<315997..>316188)
location: region:315997-316188:-1
so has part: feature:315997-316188:-1:exon
subclass of: SO_0000010

1466400
type: Gene
SIO_000068: ncbigene

position:315997:-1
position: 315997
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:316188:-1
position: 316188
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:315997-316188:-1:exon

YCR108C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YCR108C
product: uncharacterized protein
transcript id: NM_001184543.1
SIO_010081: YCR108C
subclass of: SO_0000673
so part of: YCR108C
location: complement(<315997..>316188)
location: region:315997-316188:-1
so has part: feature:315997-316188:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:315997-316188:-1:exon

YCR108C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YCR108C
note: hypothetical protein; identified by fungal homology and RT-PCR
codon start: 1
product: uncharacterized protein
translation: MPYSPSLILMGHTHTDATVYTTLKLPYSHTPIHGPFSLNQYQMHPHHYARHLPQRSIPCAIYP
SIO_010081: YCR108C
subclass of: SO_0000673
so part of: YCR108C
location: complement(315997..316188)
location: region:315997-316188:-1
so has part: feature:315997-316188:-1:exon

NP_878059.1
type: Protein
SIO_000068: ncbiprotein

S000028536
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:315997-316188:-1:exon