Saccharomyces cerevisiae S288C chromosome II, complete sequence.
type: Entry
definition: Saccharomyces cerevisiae S288C chromosome II, complete sequence.
sequence version: NC_001134.8
sequence date: 2023-01-14
sequence: sequence
division: CON
label: NC_001134.8
type: RefSeq
SIO_000068: refseq
dblink: PRJNA128
keyword: RefSeq
source: Saccharomyces cerevisiae S288C
organism: Saccharomyces cerevisiae S288C
taxonomy: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
reference: 1
references: 34897464
reference: 2
references: 8849441
reference: 3
references: 7813418
reference: 4
reference: 5
reference: 6
reference: 7
comment: REVIEWED REFSEQ: This record has been curated by SGD. The reference\nsequence is identical to BK006936.\n\nOn Apr 26, 2011 this sequence version replaced NC_001134.7.\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: SGD\nAnnotation Status :: Full Annotation\nAnnotation Version :: R64-3-1\nURL :: http://www.yeastgenome.org/\n##Genome-Annotation-Data-END##\nCOMPLETENESS: full length.

sequence
subclass of: SO_0000340
sequence length: 813184
topology: linear
so has quality: SO_0000987
location: 1..813184
location: region:1-813184:1
RO_0002162: 559292

NC_001134
type: RefSeq
SIO_000068: refseq

PRJNA128
type: BioProject
SIO_000068: bioproject

1
title: New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources
author: Engel, S.R.
author: Wong, E.D.
author: Nash, R.S.
author: Aleksander, S.
author: Alexander, M.
author: Douglass, E.
author: Karra, K.
author: Miyasato, S.R.
author: Simison, M.
author: Skrzypek, M.S.
author: Weng, S.
author: Cherry, J.M.
journal: Genetics 220 (4) (2022)
pubmed: 34897464

34897464
type: PubMed
SIO_000068: pubmed

2
title: Life with 6000 genes
author: Goffeau, A.
author: Barrell, B.G.
author: Bussey, H.
author: Davis, R.W.
author: Dujon, B.
author: Feldmann, H.
author: Galibert, F.
author: Hoheisel, J.D.
author: Jacq, C.
author: Johnston, M.
author: Louis, E.J.
author: Mewes, H.W.
author: Murakami, Y.
author: Philippsen, P.
author: Tettelin, H.
author: Oliver, S.G.
journal: Science 274 (5287), 546 (1996)
pubmed: 8849441

8849441
type: PubMed
SIO_000068: pubmed

3
title: Complete DNA sequence of yeast chromosome II
author: Feldmann, H.
author: Aigle, M.
author: Aljinovic, G.
author: Andre, B.
author: Baclet, M.C.
author: Barthe, C.
author: Baur, A.
author: Becam, A.M.
author: Biteau, N.
author: Boles, E. et al.
journal: EMBO J.
volume: 13
issue: 24
pages: 5795-5809
year: 1994
pubmed: 7813418

7813418
type: PubMed
SIO_000068: pubmed

4
title: Direct Submission
journal: Submitted (13-JAN-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA

5
title: Direct Submission
journal: Submitted (04-MAY-2012) Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA
comments: Protein update by submitter

6
title: Direct Submission
journal: Submitted (31-MAR-2011) Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA
comments: Sequence update by submitter

7
title: Direct Submission
journal: Submitted (11-DEC-2009) Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA

position:1:1
position: 1
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:813184:1
position: 813184
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

feature:1-813184:1:source
so part of: sequence
organism: Saccharomyces cerevisiae S288C
mol type: genomic DNA
strain: S288C
chromosome: II

559292
type: Taxonomy
SIO_000068: taxonomy

telomere
type: Telomere
subclass of: SO_0000624
RO_0002162: 559292
note: TEL02L; Telomeric region on the left arm of Chromosome II; annotated components include an X element core sequence, X element combinatorial repeats, and a short Y' element; TEL02L does have telomeric repeats (TEL02L-TR), but they are missing from the genome annotation due to difficulties encountered during sequencing and/or assembly
so part of: sequence
location: complement(1..6608)
location: region:1-6608:-1
so has part: feature:1-6608:-1:region

S000028867
type: SGD
SIO_000068: sgd

position:1:-1
position: 1
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:6608:-1
position: 6608
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:1-6608:-1:region

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS200; Autonomously replicating sequence
so part of: sequence
location: 40..202
location: region:40-202:1
so has part: feature:40-202:1:region

S000178039
type: SGD
SIO_000068: sgd

position:40:1
position: 40
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:202:1
position: 202
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:40-202:1:region

YBL113C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBL113C
so part of: sequence
location: complement(<280..>2658)
location: region:280-2658:-1
so has part: feature:280-2658:-1:exon
subclass of: SO_0000010

852159
type: Gene
SIO_000068: ncbigene

position:280:-1
position: 280
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:2658:-1
position: 2658
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:280-2658:-1:exon

YBL113C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBL113C
product: uncharacterized protein
transcript id: NM_001180054.1
SIO_010081: YBL113C
subclass of: SO_0000673
so part of: YBL113C
location: complement(<280..>2658)
location: region:280-2658:-1
so has part: feature:280-2658:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:280-2658:-1:exon

YBL113C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBL113C
note: Helicase-like protein encoded within the telomeric Y' element
codon start: 1
product: uncharacterized protein
translation: MDLNQRKEKKGQHVGCCGSRTDLSADTVELIERMDRLAENQATASMSIVALPSSFQESNSSDRCRKYCSSDEDSDTCIHGSANASTNATTNSSTNATTTASINVRTSATTTASINVRTSATTTESTNSNTNATTTESTNSSTNATTTASINVRTSATTTESTNSSTNATTTASINVRTSATTTESTNSSTNATTTASINVRTSATTTESTNSNTNASTNATTNSSTNATTTASTNVRTSATTNATTNSSTNATTTASTNVRTSATTTASTNVRTSATTTASINVRTSATTTESINSSTNATTTESTNSNTSATTTESTDSNTNATTTASINVRTSATTTESTNSNTSATTTESTDSNTSATTTASTNSSTNATTTASTNSSTNATTTESTNASAKEDANKDGNAEDNRFHPVTDINKESYKRKGSQMVFLERKKLKAQFPNTSENMNVLQFLGFRSDEIKHLFLYGIDIYFCPEGVFTQYGLCKGCQKMFGLCVCWAGQKVSYRRIAWEALAVERMLRNDEEYKEYLEDIEPYHGDPVGYLKYFSVKRREIYSQIQRNYAWYLAITRRRETISVLDSTRGKQGSQVFRMSGRQIKELYYKVWSNLRESKTEVLQYFLNWDEKKCREEWEAKDDTVFVEALEKVGVFQRLRSMTSAGLQGPQYVKLQFSRHHRQLRSRYELSLGMHLRDQLALGVTPSKVPHWTAFLSMLIGLFYNKTFRQKLEYLLEQISEMWLLPHWLDLANVEVLAADNTRVPLYMLMVAVHKELDSDDVPDGRFDIILLCRDSSREVGE
SIO_010081: YBL113C
subclass of: SO_0000673
so part of: YBL113C
location: complement(280..2658)
location: region:280-2658:-1
so has part: feature:280-2658:-1:exon

NP_009437.1
type: Protein
SIO_000068: ncbiprotein

S000002153
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:280-2658:-1:exon

YBL112C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBL112C
so part of: sequence
location: complement(<2582..>2899)
location: region:2582-2899:-1
so has part: feature:2582-2899:-1:exon
subclass of: SO_0000010

852160
type: Gene
SIO_000068: ncbigene

position:2582:-1
position: 2582
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:2899:-1
position: 2899
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:2582-2899:-1:exon

YBL112C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBL112C
product: uncharacterized protein
transcript id: NM_001180053.1
SIO_010081: YBL112C
subclass of: SO_0000673
so part of: YBL112C
location: complement(<2582..>2899)
location: region:2582-2899:-1
so has part: feature:2582-2899:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:2582-2899:-1:exon

YBL112C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBL112C
note: hypothetical protein; YBL112C is contained within TEL02L
codon start: 1
product: uncharacterized protein
translation: MQVLIGTKLVTEGIDIKQLMMVIMLDNRLNIIELIQGVGRLRDGGLCYLLSRKNSWAARNRKGELPPIKEGCITEQVREFYGLESKKGKKGPACWMLWLQDRPVC
SIO_010081: YBL112C
subclass of: SO_0000673
so part of: YBL112C
location: complement(2582..2899)
location: region:2582-2899:-1
so has part: feature:2582-2899:-1:exon

NP_009438.1
type: Protein
SIO_000068: ncbiprotein

S000002152
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:2582-2899:-1:exon

YBL111C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBL111C
so part of: sequence
location: complement(<2907..>5009)
location: region:2907-5009:-1
so has part: feature:2907-5009:-1:exon
subclass of: SO_0000010

852161
type: Gene
SIO_000068: ncbigene

position:2907:-1
position: 2907
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:5009:-1
position: 5009
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:2907-5009:-1:exon

YBL111C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBL111C
product: uncharacterized protein
transcript id: NM_001180052.1
SIO_010081: YBL111C
subclass of: SO_0000673
so part of: YBL111C
location: complement(join(<2907..4116,4216..>5009))
location: region:2907-5009:-1
so has part: feature:4216-5009:-1:exon
so has part: feature:2907-4116:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:4216-5009:-1:exon

position:4216:-1
position: 4216
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:2907-4116:-1:exon

position:4116:-1
position: 4116
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YBL111C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBL111C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:22842922]
note: Helicase-like protein encoded within the telomeric Y' element; relocalizes from mitochondrion to cytoplasm upon DNA replication stress
codon start: 1
product: uncharacterized protein
translation: MKVSDRRKFEKANFDEFESALNNKNDLVHCPSITLFESIPTEVRSFYEDEKSGLIKVVKFRTGAMDRKRSFEKIVVSVMVGKNVQKFLTFVEDEPDFQGGPIPSKYLIPKKINLMVYTLFQVHTLKFNRKDYDTLSLFYLNRGYYNELSFRVLERCYEIASARPNDSSTMRTFTDFVSGTPIVRSLQKSTIRKYGYNLAPYMFLLLHVDELSIFSAYQASLPGEKKVDTERLKRDLCPRKPTEIKYFSQICNDMMNKKDRLGDVLATAQRIRRRYNKNGSSEPRLKTLDGLTSERWIQWLGLESDYHCSFSSTRNAEDVVAGEAASSDHDQKISRVTRKRPREPKSTNDILVAGRKLFGSSFEFRDLHQLRLCHEIYMADTPSVAVQAPPGYGKTELFHLPLIALASKGDVKYVSFLFVPYTVLLANCMIRLGRRGCLNVAPVRNFIEEGCDGVTDLYVGIYDDLASTNFTDRIAAWENIVECTFRTNNVKLGYLIVDEFHNFETEVYRQSQFGGITNLDFDAFEKAIFLSGTAPEAVADAALQRIGLTGLAKKSMDINELKRSEDLSRGLSSYPTRMFNLIKEKSEVPLGHVHKIWKKVESQPEEALKLLLALFEIEPESKAIVVASTTNEVEELACSWRKYFRVVWIHGKLGCCRKGVSHKGVCH
SIO_010081: YBL111C
subclass of: SO_0000673
so part of: YBL111C
location: complement(join(2907..4116,4216..5009))
location: region:2907-5009:-1
so has part: feature:4216-5009:-1:exon
so has part: feature:2907-4116:-1:exon

NP_009439.1
type: Protein
SIO_000068: ncbiprotein

S000002151
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:4216-5009:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:2907-4116:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS201; Autonomously replicating sequence
so part of: sequence
location: 6498..6620
location: region:6498-6620:1
so has part: feature:6498-6620:1:region

S000178040
type: SGD
SIO_000068: sgd

position:6498:1
position: 6498
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:6620:1
position: 6620
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:6498-6620:1:region

YBL108C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PAU9
locus tag: YBL108C-A
so part of: sequence
location: complement(<7605..>7733)
location: region:7605-7733:-1
so has part: feature:7605-7733:-1:exon
subclass of: SO_0000010

852163
type: Gene
SIO_000068: ncbigene

position:7605:-1
position: 7605
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:7733:-1
position: 7733
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:7605-7733:-1:exon

YBL108C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PAU9
locus tag: YBL108C-A
product: seripauperin PAU9
transcript id: NM_001184458.1
SIO_010081: YBL108C-A
subclass of: SO_0000673
so part of: YBL108C-A
location: complement(<7605..>7733)
location: region:7605-7733:-1
so has part: feature:7605-7733:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:7605-7733:-1:exon

YBL108C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PAU9
locus tag: YBL108C-A
note: hypothetical protein; member of the seripauperin multigene family encoded mainly in subtelomeric regions; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum and vacuole respectively
codon start: 1
product: seripauperin PAU9
translation: MLTGIAPDQVTRMITGVPWYSSRLKPAISSALSKDGIYTIAN
SIO_010081: YBL108C-A
subclass of: SO_0000673
so part of: YBL108C-A
location: complement(7605..7733)
location: region:7605-7733:-1
so has part: feature:7605-7733:-1:exon

NP_076873.1
type: Protein
SIO_000068: ncbiprotein

S000007592
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:7605-7733:-1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 8848..9092
location: region:8848-9092:1
so has part: feature:8848-9092:1:region

S000006798
type: SGD
SIO_000068: sgd

position:8848:1
position: 8848
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:9092:1
position: 9092
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:8848-9092:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty2 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 9093..9424
location: region:9093-9424:1
so has part: feature:9093-9424:1:region

S000006799
type: SGD
SIO_000068: sgd

position:9093:1
position: 9093
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:9424:1
position: 9424
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:9093-9424:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 9425..9518
location: region:9425-9518:1
so has part: feature:9425-9518:1:region

S000006800
type: SGD
SIO_000068: sgd

position:9425:1
position: 9425
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:9518:1
position: 9518
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:9425-9518:1:region

YNCB0001W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCB0001W
so part of: sequence
location: 9583..9666
location: region:9583-9666:1
so has part: feature:9583-9666:1:exon
subclass of: SO_0000663

852166
type: Gene
SIO_000068: ncbigene

position:9583:1
position: 9583
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:9666:1
position: 9666
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:9583-9666:1:exon

YNCB0001W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCB0001W
product: tRNA-Leu
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
experiment: EXISTENCE:direct assay:GO:0030371 translation repressor activity [PMID:27609601]
experiment: EXISTENCE:direct assay:GO:0043022 ribosome binding [PMID:27609601]
experiment: EXISTENCE:direct assay:GO:0043555 regulation of translation in response to stress [PMID:27609601]
note: Leucine tRNA (tRNA-Leu), predicted by tRNAscan-SE analysis
SIO_010081: YNCB0001W
subclass of: SO_0000673
so part of: YNCB0001W
location: 9583..9666
location: region:9583-9666:1
so has part: feature:9583-9666:1:exon

S000006647
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:9583-9666:1:exon

YBL107C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MIC23
gene: MIX23
locus tag: YBL107C
gene synonym: MIC23
so part of: sequence
location: complement(<9961..>10551)
location: region:9961-10551:-1
so has part: feature:9961-10551:-1:exon
subclass of: SO_0000010

852167
type: Gene
SIO_000068: ncbigene

position:9961:-1
position: 9961
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:10551:-1
position: 10551
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:9961-10551:-1:exon

YBL107C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MIC23
gene: MIX23
locus tag: YBL107C
gene synonym: MIC23
product: Mix23p
transcript id: NM_001178347.1
SIO_010081: YBL107C
subclass of: SO_0000673
so part of: YBL107C
location: complement(<9961..>10551)
location: region:9961-10551:-1
so has part: feature:9961-10551:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:9961-10551:-1:exon

YBL107C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MIC23
gene: MIX23
locus tag: YBL107C
gene synonym: MIC23
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005758 mitochondrial intermembrane space [PMID:22984289]
note: Mitochondrial intermembrane space hypothetical protein; imported via the MIA import machinery; contains an unusual twin cysteine motif (CX13C CX14C)
codon start: 1
product: Mix23p
translation: MVDNRRTFTAPQSLLETNLTFPNDEPSLTTITVTRERCVDPSLIDSFLRFLRHGSDDIIRQKLNNYRKGSINGKNKCKEFLKQELYPNWQIRNNIISFCEKEAAEMKNETDQQCGNNKKTTAEPLIDARIDPYAARERAEKQEAQYKDWTKVTEWVANNRKIEQILTSTTEGILRQNCEQNNDYLKEFTQFCKDNS
SIO_010081: YBL107C
subclass of: SO_0000673
so part of: YBL107C
location: complement(9961..10551)
location: region:9961-10551:-1
so has part: feature:9961-10551:-1:exon

NP_009443.1
type: Protein
SIO_000068: ncbiprotein

S000000203
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:9961-10551:-1:exon

YBL106C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SNI2
alternative label: SOP2
gene: SRO77
locus tag: YBL106C
gene synonym: SNI2; SOP2
so part of: sequence
location: complement(<10847..>13879)
location: region:10847-13879:-1
so has part: feature:10847-13879:-1:exon
subclass of: SO_0000010

852168
type: Gene
SIO_000068: ncbigene

position:10847:-1
position: 10847
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:13879:-1
position: 13879
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:10847-13879:-1:exon

YBL106C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SNI2
alternative label: SOP2
gene: SRO77
locus tag: YBL106C
gene synonym: SNI2; SOP2
product: putative Rab GTPase-binding protein SRO77
transcript id: NM_001178346.2
SIO_010081: YBL106C
subclass of: SO_0000673
so part of: YBL106C
location: complement(<10847..>13879)
location: region:10847-13879:-1
so has part: feature:10847-13879:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:10847-13879:-1:exon

YBL106C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SNI2
alternative label: SOP2
gene: SRO77
locus tag: YBL106C
gene synonym: SNI2; SOP2
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0006887 exocytosis [PMID:10402465]
experiment: EXISTENCE:genetic interaction:GO:0006893 Golgi to plasma membrane transport [PMID:10402465]
experiment: EXISTENCE:physical interaction:GO:0005886 plasma membrane [PMID:10402465]
experiment: EXISTENCE:physical interaction:GO:0006893 Golgi to plasma membrane transport [PMID:10402465]
note: Protein with roles in exocytosis and cation homeostasis; functions in docking and fusion of post-Golgi vesicles with plasma membrane; regulates cell proliferation and colony development via the Rho1-Tor1 pathway; interacts with SNARE protein Sec9p; homolog of Drosophila lethal giant larvae tumor suppressor; SRO77 has a paralog, SRO7, that arose from the whole genome duplication
codon start: 1
product: putative Rab GTPase-binding protein SRO77
translation: MFKKSRHLKNVSNAIKSARVHDVSNGINSKFFDTKKICTYGINGRITVTTFDYTQSLLAVATTAGEIHVYGQKQIEVVFTLKNRPQIKHMRFIKGIYLIAVDEKSNIIVLSVHSKQILTTVFCPNSITCIETDPSLDWMLIGLESGSILIYDVDRNQMSKLKIENFQKSVFLPKERLSPVISIQWNPRDIGTILISYEHITVIYSFIDYKVKQHFFYQLEPYAPGGDLSTNIEKKRTPKVIQSLYHPNSLHILTVHEDNSLVFWDVNSGKLIHARSIFETHVNFPNPALKDCSFTETPAIFKVSWLCQRNPEYTSLLIATKATENPCLPQEITMIDLGGTPMYSVTSFDAMSKYYAKPVQQKLFSLIGKAPLINFLPLPKASPYFGGCHDTNLILLLLEDGELETLIYPAGSFSSKASIFPRSLAWVRPTVTTCIAQSVQKNLWLGMMTIAQSESFLKGGIPATRNIRRHETRSALLTGHSNGSVRIWDASHSEVTDNAVFEVNTAKVLNRATNLAIKNISFASETLELAVSSEVGDVILFKFETNKFYGQLPKSDALQLKFSRFSLDDSKTILVDVSDRGPTNVKQGFIPSTVIHAKKGAVSAIMNSNIGFVAVGFIEGTLIILDRRGPAIIFNENIRVISKAGSSYVSTVHFCVMEYGDDGFSSILMLCGTDIGELMTFKILPATNGRFEVKFTDATKTNNQGKILGINSFAKDTGYSCSATISKMQGLSKGIAIPGFVTISGANDIRLVSPGKSKDTHALFKYPIATSGLSFIPIIDGKGERKLSTIMIVLLINGDIKVLTVPELKEVKNLRCPVPLSAQYVENSSILENGDIVIRTGKFQASLISVLNESATGTNHTADISQHTPIDTLYNPDLKIGYRPQVNSLQWARGTIYCTPYQLDELLGGIERPESKYEESAIARGCISSSSSNAARKLPPGTEDHRYARPVRSSGRSNGYGVLKSVSRAIETRLDTVETTINDYATTMGQTMNDAMEETGRDMMKSAVGF
SIO_010081: YBL106C
subclass of: SO_0000673
so part of: YBL106C
location: complement(10847..13879)
location: region:10847-13879:-1
so has part: feature:10847-13879:-1:exon

NP_009444.2
type: Protein
SIO_000068: ncbiprotein

S000000202
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:10847-13879:-1:exon

YBL105C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CLY15
alternative label: CLY5
alternative label: CLY7
alternative label: HPO2
alternative label: RSF8
alternative label: STT1
gene: PKC1
locus tag: YBL105C
gene synonym: CLY15; CLY5; CLY7; HPO2; RSF8; STT1
so part of: sequence
location: complement(<14241..>17696)
location: region:14241-17696:-1
so has part: feature:14241-17696:-1:exon
subclass of: SO_0000010

852169
type: Gene
SIO_000068: ncbigene

position:14241:-1
position: 14241
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:17696:-1
position: 17696
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:14241-17696:-1:exon

YBL105C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CLY15
alternative label: CLY5
alternative label: CLY7
alternative label: HPO2
alternative label: RSF8
alternative label: STT1
gene: PKC1
locus tag: YBL105C
gene synonym: CLY15; CLY5; CLY7; HPO2; RSF8; STT1
product: protein kinase C
transcript id: NM_001178345.2
SIO_010081: YBL105C
subclass of: SO_0000673
so part of: YBL105C
location: complement(<14241..>17696)
location: region:14241-17696:-1
so has part: feature:14241-17696:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:14241-17696:-1:exon

YBL105C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CLY15
alternative label: CLY5
alternative label: CLY7
alternative label: HPO2
alternative label: RSF8
alternative label: STT1
gene: PKC1
locus tag: YBL105C
gene synonym: CLY15; CLY5; CLY7; HPO2; RSF8; STT1
EC number: 2.7.11.13
experiment: EXISTENCE:direct assay:GO:0004697 protein kinase C activity [PMID:26179915|PMID:8207005]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:11545731]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11545731]
experiment: EXISTENCE:direct assay:GO:0005856 cytoskeleton [PMID:15910746]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:16622836]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0010494 cytoplasmic stress granule [PMID:32184286]
experiment: EXISTENCE:direct assay:GO:0030427 site of polarized growth [PMID:10893184]
experiment: EXISTENCE:direct assay:GO:0032165 prospore septin filament array [PMID:24390141]
experiment: EXISTENCE:direct assay:GO:0034063 stress granule assembly [PMID:32184286]
experiment: EXISTENCE:mutant phenotype:GO:0007165 signal transduction [PMID:7874200]
experiment: EXISTENCE:mutant phenotype:GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly [PMID:21163942]
experiment: EXISTENCE:mutant phenotype:GO:0030242 autophagy of peroxisome [PMID:20385774]
experiment: EXISTENCE:mutant phenotype:GO:0032186 cellular bud neck septin ring organization [PMID:26179915]
experiment: EXISTENCE:mutant phenotype:GO:0035556 intracellular signal transduction [PMID:7874200]
experiment: EXISTENCE:mutant phenotype:GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening [PMID:21163942]
experiment: EXISTENCE:mutant phenotype:GO:0060237 regulation of fungal-type cell wall organization [PMID:7874200]
note: Protein serine/threonine kinase; essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC)
codon start: 1
product: protein kinase C
translation: MSFSQLEQNIKKKIAVEENIIRGASALKKKTSNVMVIQKCNTNIREARQNLEYLEDSLKKLRLKTAQQSQGENGSEDNERCNSKEYGFLSTKSPNEHIFSRLDLVKYDCPSLAQRIQYMLQQLEFKLQVEKQYQEANTKLTKLYQIDGDQRSSSAAEGGAMESKYRIQMLNKALKKYQAINVDFDQFKHQPNDIMDNQQPKFRRKQLTGVLTIGITAARDVDHIQSPMFARKPESYVTIKIDDTIKARTKPSRNDRWSEDFQIPVEKGNEIEITVYDKVNDSLIPVAIMWLLLSDIAEEIRKKKAGQTNEQQGWVNASNINGGSSLASEEGSTLTSTYSNSAIQSTSAKNVQGENTSTSQISTNSWFVLEPSGQILLTLGFHKSSQIERKQLMGGLHRHGAIINRKEEIFEQHGHHFVQKSFYNIMCCAYCGDFLRYTGFQCQDCKFLCHKKCYTNVVTKCIAKTSTDTDPDEAKLNHRIPHRFLPTSNRGTKWCCHCGYILPWGRHKVRKCSECGIMCHAQCAHLVPDFCGMSMEMANKILKTIQDTKRNQEKKKRTVPSAQLGSSIGTANGSDLSPSKLAERANAPLPPQPRKHDKTPSPQKVGRDSPTKQHDPIIDKRISLQTHGREKLNKFIDENEAYLNFTEGAQQTAEFSSPEKTLDPTSNRRSLGLTDLSIEHSQTWESKDDLMRDELELWKAQREEMELEIKQDSGEIQEDLEVDHIDLETKQKLDWENKNDFREADLTIDSTHTNPFRDMNSETFQIEQDHASKEVLQETVSLAPTSTHASRTTDQQSPQKSQTSTSAKHKKRAAKRRKVSLDNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQRLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAILTDEPLYPIDMAGEIVQIFQGLLTKDPEKRLGAGPRDADEVMEEPFFRNINFDDILNLRVKPPYIPEIKSPEDTSYFEQEFTSAPPTLTPLPSVLTTSQQEEFRGFSFMPDDLDL
SIO_010081: YBL105C
subclass of: SO_0000673
so part of: YBL105C
location: complement(14241..17696)
location: region:14241-17696:-1
so has part: feature:14241-17696:-1:exon

NP_009445.2
type: Protein
SIO_000068: ncbiprotein

S000000201
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:14241-17696:-1:exon

YBL104C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YBL103C-A
gene: SEA4
locus tag: YBL104C
gene synonym: YBL103C-A
so part of: sequence
location: complement(<18177..>21293)
location: region:18177-21293:-1
so has part: feature:18177-21293:-1:exon
subclass of: SO_0000010

852170
type: Gene
SIO_000068: ncbigene

position:18177:-1
position: 18177
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:21293:-1
position: 21293
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:18177-21293:-1:exon

YBL104C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YBL103C-A
gene: SEA4
locus tag: YBL104C
gene synonym: YBL103C-A
product: Sea4p
transcript id: NM_001178344.1
SIO_010081: YBL104C
subclass of: SO_0000673
so part of: YBL104C
location: complement(<18177..>21293)
location: region:18177-21293:-1
so has part: feature:18177-21293:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:18177-21293:-1:exon

YBL104C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YBL103C-A
gene: SEA4
locus tag: YBL104C
gene synonym: YBL103C-A
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0035859 Seh1-associated complex [PMID:21454883]
experiment: EXISTENCE:genetic interaction:GO:1904263 positive regulation of TORC1 signaling [PMID:23716719]
note: Subunit of SEACAT, a subcomplex of the SEA complex; Sea4p, along with Rtc1p and Mtc5p, redundantly inhibit the TORC1 inhibitory role of the Iml1p/SEACIT (Iml1p-Npr2p-Npr3p) subcomplex, a GAP for GTPase Gtr1p (EGOC subunit) in response to amino acid limitation, thereby resulting in activation of TORC1 signaling; SEA is a coatomer-related complex that associates dynamically with the vacuole; contains an N-terminal beta-propeller fold and a C-terminal RING motif
codon start: 1
product: Sea4p
translation: MGLIKKVTHWSYDNLIDYLSVNPTRDEVTHYKVDPENESDESIIKLHTVKDFGSITCLDYSESEIGMIGVGEKNGYLRIFNISGQNSSSPASHAPVGLNANNETSMTNASGGKAAQAENIVGSVSNLKDTQGYPVSETNYDIRVRAKKQRCINSLGINTNGLIAMGLDRNKHDSSLQIWDMNYHDDSHETINPMFSYCTNESIVSLKFLNDTSVLAASTKFLKEIDVRSPNPIYQHPTRLTYDIKLNPFNDWQFSTYGDDGTLAIWDRRKLSDQASLGDLNVASPLLTFEKLVGSGAASRKYMNSCFRWSCVRNNEFATLHRGDTIKRWRLGYYCDSNRDIAADDDNEMNIENLFVSSVHDTNTMYDRVATFDYIPRSNNGTSLICMRQSGTIYRMPISEVCSKAILNNRNSLLLSNFENTEIDEIRVNNEHEKSNLENVKTILKNLSFEDLDVSEDYFPSGHDEPNNEIEYSELSEEENEGSNDVLDSKRGFELFWKPEKLLEKDISVIMRTRASLGYGLDPMNTVEMIDSSKNLQNNAYIRNTWRWIAIAKASVDDGTMVSGDLDLGYEGVIGIWNGINGISNQDRYRQETILSDKQLNKEMEKIIKLRRKNRDRNSPIANAAGSPKYVQRRLCLIISGWDLSRSDYEDKYNIIMKNGHYEKAAAWAVFFGDIPKAVEILGSAKKERLRLIATAIAGYLAYKDLPGNNAWRQQCRKMSSELDDPYLRVIFAFIADNDWWDILYEPAISLRERLGVALRFLNDTDLTTFLDRTSSTVIENGELEGLILTGITPNGIDLLQSYVNKTSDVQSAALISIFGSPRYFRDQRVDEWIQTYRDMLKSWELFSMRARFDVLRSKLSRTKTGVLTADIKPRQIYIQCQNCKQNINTPRTSSPSSAVSTSAGNYKNGEAYRRNNADYKKFNTGSSEAQAADEKPRHKYCCPHCGSSFPRCAICLMPLGTSNLPFVINGTQSRDPMQTEDSQDGANRELVSRKLKLNEWFSFCLSCNHGMHAGHAEEWFDRHNVCPTPGCTCQCNK
SIO_010081: YBL104C
subclass of: SO_0000673
so part of: YBL104C
location: complement(18177..21293)
location: region:18177-21293:-1
so has part: feature:18177-21293:-1:exon

NP_009446.2
type: Protein
SIO_000068: ncbiprotein

S000000200
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:18177-21293:-1:exon

YBL103C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RTG3
locus tag: YBL103C
so part of: sequence
location: complement(<22076..>23536)
location: region:22076-23536:-1
so has part: feature:22076-23536:-1:exon
subclass of: SO_0000010

852171
type: Gene
SIO_000068: ncbigene

position:22076:-1
position: 22076
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:23536:-1
position: 23536
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:22076-23536:-1:exon

YBL103C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RTG3
locus tag: YBL103C
product: Rtg3p
transcript id: NM_001178343.1
SIO_010081: YBL103C
subclass of: SO_0000673
so part of: YBL103C
location: complement(<22076..>23536)
location: region:22076-23536:-1
so has part: feature:22076-23536:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:22076-23536:-1:exon

YBL103C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RTG3
locus tag: YBL103C
experiment: EXISTENCE:direct assay:GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific [PMID:9032238]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:10848632]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:10848632]
experiment: EXISTENCE:direct assay:GO:0031930 mitochondria-nucleus signaling pathway [PMID:9032238]
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:19158363]
experiment: EXISTENCE:direct assay:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:9032238|PMID:9242640]
experiment: EXISTENCE:mutant phenotype:GO:0000422 autophagy of mitochondrion [PMID:19840933]
experiment: EXISTENCE:mutant phenotype:GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific [PMID:9032238]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:12393187|PMID:9032238|PMID:9242640]
experiment: EXISTENCE:mutant phenotype:GO:0071400 cellular response to oleic acid [PMID:12069115|PMID:12393187]
experiment: EXISTENCE:physical interaction:GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding [PMID:9867831]
note: bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways; forms a complex with another bHLH/Zip protein, Rtg1p, to activate the pathways; target of Hog1p
codon start: 1
product: Rtg3p
translation: MMNNNESEAENQRLLDELMNQTKVLQETLDFSLVTPTPHHNDDYKIHGSAYPGGETPAQQHEKLSYINTHNSNDNNNLMGSQARSNSQTPTASTIYEEAESQSSYLDDMFRTSQGGRPVTQNSISSIGQGPLRSSYSMAYDSPVDRAMNTPLQQQEGLKAELPHDFLFQHGTDDTMYNLTDDLSSSLSSSINSDMMTPNTYSSSFSYNPQSLGPASVSSTYSPKVRSPSSSFRAGSFLSSSFRHGSINTPRTRHTSISSNMTENIGPGSVPKILGGLTSDEKLRRKREFHNAVERRRRELIKQKIKELGQLVPPSLLNYDDLGKQIKPNKGIILDRTVEYLQYLAEILEIQARKKKALLAKIKELEEKKSSVAALSPFTNNHHASSGQNNSENSEERIIDIRSVPNALMNEQNSKAELHNWEPPLYDSVGNHNHAGTMESHPHTNIHEELKEFLSGDLIEAEDNAKLMFGDDNSNPADYLLEFGSG
SIO_010081: YBL103C
subclass of: SO_0000673
so part of: YBL103C
location: complement(22076..23536)
location: region:22076-23536:-1
so has part: feature:22076-23536:-1:exon

NP_009447.1
type: Protein
SIO_000068: ncbiprotein

S000000199
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:22076-23536:-1:exon

YBL102W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SFT2
locus tag: YBL102W
so part of: sequence
location: <24098..>24745
location: region:24098-24745:1
so has part: feature:24098-24745:1:exon
subclass of: SO_0000010

852172
type: Gene
SIO_000068: ncbigene

position:24098:1
position: 24098
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:24745:1
position: 24745
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:24098-24745:1:exon

YBL102W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SFT2
locus tag: YBL102W
product: Sft2p
transcript id: NM_001178342.1
SIO_010081: YBL102W
subclass of: SO_0000673
so part of: YBL102W
location: <24098..>24745
location: region:24098-24745:1
so has part: feature:24098-24745:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:24098-24745:1:exon

YBL102W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SFT2
locus tag: YBL102W
experiment: EXISTENCE:direct assay:GO:0000138 Golgi trans cisterna [PMID:7596416]
experiment: EXISTENCE:direct assay:GO:0000139 Golgi membrane [PMID:10406798|PMID:9725919]
experiment: EXISTENCE:genetic interaction:GO:0042147 retrograde transport, endosome to Golgi [PMID:10406798]
note: Tetra-spanning membrane protein found mostly in the late Golgi; non-essential; can suppress some sed5 alleles; may be part of the transport machinery, but precise function is unknown; similar to mammalian syntaxin 5
codon start: 1
product: Sft2p
translation: MSEEPPSDQVNSLRDSLNRWNQTRQQNSQGFNESAKTLFSSWADSLNTRAQDIYQTLPVSRQDLVQDQEPSWFQLSRTERMVLFVCFLLGATACFTLCTFLFPVLAAKPRKFGLLWTMGSLLFVLAFGVLMGPLAYLKHLTARERLPFSMFFFATCFMTIYFAAFSKNTVLTITCALLELVAVIYYAISYFPFGATGLRMLSSAGVNSARGVLRI
SIO_010081: YBL102W
subclass of: SO_0000673
so part of: YBL102W
location: 24098..24745
location: region:24098-24745:1
so has part: feature:24098-24745:1:exon

NP_009448.1
type: Protein
SIO_000068: ncbiprotein

S000000198
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:24098-24745:1:exon

YBL101C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ART2
gene: ECM21
locus tag: YBL101C
gene synonym: ART2
so part of: sequence
location: complement(<24946..>28299)
location: region:24946-28299:-1
so has part: feature:24946-28299:-1:exon
subclass of: SO_0000010

852173
type: Gene
SIO_000068: ncbigene

position:24946:-1
position: 24946
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:28299:-1
position: 28299
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:24946-28299:-1:exon

YBL101C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ART2
gene: ECM21
locus tag: YBL101C
gene synonym: ART2
product: Ecm21p
transcript id: NM_001178341.1
SIO_010081: YBL101C
subclass of: SO_0000673
so part of: YBL101C
location: complement(<24946..>28299)
location: region:24946-28299:-1
so has part: feature:24946-28299:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:24946-28299:-1:exon

YBL101C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ART2
gene: ECM21
locus tag: YBL101C
gene synonym: ART2
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0070086 ubiquitin-dependent endocytosis [PMID:18976803|PMID:32744498|PMID:31658248]
experiment: EXISTENCE:physical interaction:GO:0031625 ubiquitin protein ligase binding [PMID:18976803]
experiment: EXISTENCE:physical interaction:GO:0070086 ubiquitin-dependent endocytosis [PMID:18976803]
note: Alpha-arrestin, ubiquitin ligase adaptor for Rsp5p; regulates starvation- and substrate-induced Ub-dependent endocytosis of select plasma membrane localized amino acid transporters; substrate of Rsp5p-mediated Lys63-polyubiquitination and Ubp2-mediated deubiquitination; promoter contains several Gcn4p binding sites required for induction in response to starvation via Gcn4p and the general amino acid control pathway; ECM21 has a paralog, CSR2, that arose from the whole genome duplication
codon start: 1
product: Ecm21p
translation: MPFITSRPVAKNSSHSLSETDLNQSKGQPFQPSPTKKLGSMQQRRRSSTIRHALSSLLGGANVHSPAVLNNTTKGGNNNGNIRSSNTDAQLLGKKQNKQPPPNARRHSTTAIQGSISDSATTTPRSSTSDTNRRTSGRLSVDQEPRISGGRYSQIEEDSTVLDFDDDHNSSAVVSSDLSSTSLTRLANSKKFNEQFLIEYLTARGLLGPKTVLSNEYLKISISTSGESVFLPTISSNDDEYLSRLNGLNDGTDDAEADFFMDGIDQQEGNTPSLATTAAATESGGSINENRDTLLRENNSGDHPGSGSELNTRSVEIDSSMVSYSIAVIVSVKKPTRFTDMQLELCSRVKVFWNTGVPPTKTFNEEFYNAASMKWNLNDENFDLFVPLSISPDDQMIENNSNDRQMRLFKNIPTEERLYLDKTKTKASLLNAIDVNKTHLYQPGDYVFLVPVVFSNHIPETIYLPSARVSYRLRLATKAINRKGFYRQDSNSPQPIVSPDSSSSLSSTTSSLKLTETESAQAHRRISNTLFSKVKNHLHMSSHQLKNEESGEEDIFAEYPIKVIRTPPPVAVSTANKPIYINRVWTDSLSYEISFAQKYVSLNSEVPIKIKLAPICKNVCVKRIHVSITERVTFVSKGYEYEYDQTDPVAKDPYNPYYLDFASKRRKERSVSLFEIRTKEKGTRALREEIVENSFNDNLLSYSPFDDDSDSKGNPKERLGITEPIIIETKLKFPKYEDLDKRTAKIIPPYGIDAYTSIPNPEHAVANGPSHRRPSVIGFLSGHKGSKSHEENEKPVYDPKFHQTIIKSNSGLPVKTHTRLNTPKRGLYLDSLHFSNVYCRHKLEIMLRISKPDPECPSKLRHYEVLIDTPIFLVSEQCNSGNMELPTYDMATMEGKGNQVPLSMNSDFFGNTCPPPPTFEEAISVPASPIVSPMGSPNIMASYDPDLLSIQQLNLSRTTSVSGPSGYSDDAGVPNVNRNSISNANAMNGSISNSAFVSGNSGQGVARARATSVNDRSRFNNLDKLLSTPSPVNRSHNSSPTNGLSQANGTVRIPNATTENSKDKQNEFFKKGYTLANVKDDEEQEGIVSSSSADSLLSHGNEPPRYDEIVPLMSDEE
SIO_010081: YBL101C
subclass of: SO_0000673
so part of: YBL101C
location: complement(24946..28299)
location: region:24946-28299:-1
so has part: feature:24946-28299:-1:exon

NP_009449.1
type: Protein
SIO_000068: ncbiprotein

S000000197
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:24946-28299:-1:exon

YBL100W-C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YBL101W-C
locus tag: YBL100W-C
gene synonym: YBL101W-C
so part of: sequence
location: <28427..>28546
location: region:28427-28546:1
so has part: feature:28427-28546:1:exon
subclass of: SO_0000010

1466439
type: Gene
SIO_000068: ncbigene

position:28427:1
position: 28427
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:28546:1
position: 28546
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:28427-28546:1:exon

YBL100W-C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YBL101W-C
locus tag: YBL100W-C
gene synonym: YBL101W-C
product: uncharacterized protein
transcript id: NM_001184585.1
SIO_010081: YBL100W-C
subclass of: SO_0000673
so part of: YBL100W-C
location: <28427..>28546
location: region:28427-28546:1
so has part: feature:28427-28546:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:28427-28546:1:exon

YBL100W-C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YBL101W-C
locus tag: YBL100W-C
gene synonym: YBL101W-C
note: hypothetical protein; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
codon start: 1
product: uncharacterized protein
translation: MSRSIFFFSSLFLSPLNKIRNIGGKVENPWKSQIRDWKN
SIO_010081: YBL100W-C
subclass of: SO_0000673
so part of: YBL100W-C
location: 28427..28546
location: region:28427-28546:1
so has part: feature:28427-28546:1:exon

NP_878043.1
type: Protein
SIO_000068: ncbiprotein

S000028598
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:28427-28546:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS230; Autonomously Replicating Sequence
so part of: sequence
location: 28942..29160
location: region:28942-29160:1
so has part: feature:28942-29160:1:region

S000118996
type: SGD
SIO_000068: sgd

position:28942:1
position: 28942
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:29160:1
position: 29160
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:28942-29160:1:region

mobile_element
type: Mobile Element
subclass of: SO_0001037
RO_0002162: 559292
note: YBLWTy2-1; Ty2 element, LTR retrotransposon of the Copia (Pseudoviridae) group; contains co-transcribed genes TYA Gag and TYB Pol, encoding proteins involved in structure and function of virus-like particles, flanked by two direct repeats
mobile element type: retrotransposon:YBLWTy2-1
so part of: sequence
location: 29644..35602
location: region:29644-35602:1
so has part: feature:29644-35602:1:region

S000006809
type: SGD
SIO_000068: sgd

position:29644:1
position: 29644
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:35602:1
position: 35602
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:29644-35602:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty2 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 29644..29975
location: region:29644-29975:1
so has part: feature:29644-29975:1:region

S000006801
type: SGD
SIO_000068: sgd

position:29975:1
position: 29975
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:29644-29975:1:region

YBL100W-B
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YBL101W-B
locus tag: YBL100W-B
gene synonym: YBL101W-B
so part of: sequence
location: <29935..>35248
location: region:29935-35248:1
so has part: feature:29935-35248:1:exon
subclass of: SO_0000010

852175
type: Gene
SIO_000068: ncbigene

position:29935:1
position: 29935
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:35248:1
position: 35248
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:29935-35248:1:exon

YBL100W-B
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YBL101W-B
locus tag: YBL100W-B
gene synonym: YBL101W-B
product: gag-pol fusion protein
transcript id: NM_001180050.2
SIO_010081: YBL100W-B
subclass of: SO_0000673
so part of: YBL100W-B
location: <29935..>35248
location: region:29935-35248:1
so has part: feature:29935-35248:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:29935-35248:1:exon

YBL100W-B
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YBL101W-B
locus tag: YBL100W-B
gene synonym: YBL101W-B
EC number: 2.7.7.7
EC number: 2.7.7.49
EC number: 3.1.26.4
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:9448009]
ribosomal slippage: true
note: Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes
codon start: 1
product: gag-pol fusion protein
translation: MESQQLHQNPHSLHGSAYASVTSKEVSSNQDPLAVSASNLPEFDRDSTKVNSQQETTPGTSAVPENHHHVSPQPASVPPPQNGQYQQHGMMTPNKAMASNWAHYQQPSMMTCSHYQTSPAYYQPDPHYPLPQYIPPLSTSSPDPIDSQDQHSEVPQAKTKVRNNVLPPHTLTSEENFYTWVKFYIRFLKNSNLGDIIPNDQGEIKRQMTYEEHAYIYNTFQAFAPFHLLPTWVKQILEINYADILTVLCKSVSKMQTNNQELKDWIALANLEYDGSTSADTFEITVSTIIQRLKENNINVSDRLACQLILKGLSGDFKYLRNQYRTKTNMKLSQLFAEIQLIYDENKIMNLNKPSQYKQHSEYKNVSRTSPNTTNTKVTTRNYHRTNSSKPRAAKAHNIATSSKFSRVNNDHINESTVSSQYLSDDNELSLGQQQKESKPTHTIDSNDELPDHLLIDSGASQTLVRSAHYLHHATPNSEINIVDAQKQDIPINAIGNLHFNFQNGTKTSIKALHTPNIAYDLLSLSELANQNITACFTRNTLERSDGTVLAPIVKHGDFYWLSKKYLIPSHISKLTINNVNKSKSVNKYPYPLIHRMLGHANFRSIQKSLKKNAVTYLKESDIEWSNASTYQCPDCLIGKSTKHRHVKGSRLKYQESYEPFQYLHTDIFGPVHHLPKSAPSYFISFTDEKTRFQWVYPLHDRREESILNVFTSILAFIKNQFNARVLVIQMDRGSEYTNKTLHKFFTNRGITACYTTTADSRAHGVAERLNRTLLNDCRTLLHCSGLPNHLWFSAVEFSTIIRNSLVSPKNDKSARQHAGLAGLDITTILPFGQPVIVNNHNPDSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQDNQSKLDQFNYDTLTFDDDLNRLTAHNQSFIEQNETEQSYDQNTESDHDYQSEIEINSDPLVNDFSSQSMNPLQLDHEPVQKVRALKEVDADISEYNILPSPVRSRTPHIINKESTEMGGTIESDTTSPRHSSTFTARNQKRPGSPNDMIDLTSQDRVNYELENIKTTRLGGTEEPYIQRNSDTNIKYRTTNSTPSIDDRSPDSDSTTPIISIETKAACDNTPSIDTDPPEYRSSDHATPNIMPDKSSKNVTADSILDDLPLPDLTNKSPTDTSDVSKDIPHIHSRQTNSSLGGMDDSNVLTTTKSKKRSLEDNETEIEVSRDTWNNKNMRSLEPPRSKKRINLIAAIKGVKSIKPVRTTLRYDEAITYNEDNKEKDRYIEAYHKEINQLLRMNTWDTNKYYDRNDIDPKKVINSMFIFNKKRDGTHKARFVARGDIQHPDTYDSDMQSNTVHHYALMTSLSIALDNDYYITQLDISSAYLYADIKEELYIRPPPHLGLNDKLLRLRKSLYGLKQSGANWYETIKSYLINCCDMQEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANEKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRSKYMKLGMEKSLTEKLPKLNVPLNPKGKKLSAPGQPGHYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTKPDNKLVAISDASYGNQPYYKSQIGNIFLLNGKVIGGKSTKASLTCTSTTEAEIHAVSEAIPLLNNLSHLVQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYYIETKKNIADVMTKPLPIKTFKLLTNKWIH
SIO_010081: YBL100W-B
subclass of: SO_0000673
so part of: YBL100W-B
location: join(29935..31227,31229..35248)
location: region:29935-35248:1
so has part: feature:29935-31227:1:exon
so has part: feature:31229-35248:1:exon

NP_009450.1
type: Protein
SIO_000068: ncbiprotein

S000002149
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:29935-31227:1:exon

position:31227:1
position: 31227
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:31229-35248:1:exon

position:31229:1
position: 31229
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YBL100W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YBL101W-A
locus tag: YBL100W-A
gene synonym: YBL101W-A
so part of: sequence
location: <29935..>31251
location: region:29935-31251:1
so has part: feature:29935-31251:1:exon
subclass of: SO_0000010

852174
type: Gene
SIO_000068: ncbigene

position:31251:1
position: 31251
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:29935-31251:1:exon

YBL100W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YBL101W-A
locus tag: YBL100W-A
gene synonym: YBL101W-A
product: gag protein
transcript id: NM_001180049.1
SIO_010081: YBL100W-A
subclass of: SO_0000673
so part of: YBL100W-A
location: <29935..>31251
location: region:29935-31251:1
so has part: feature:29935-31251:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:29935-31251:1:exon

YBL100W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YBL101W-A
locus tag: YBL100W-A
gene synonym: YBL101W-A
note: Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag
codon start: 1
product: gag protein
translation: MESQQLHQNPHSLHGSAYASVTSKEVSSNQDPLAVSASNLPEFDRDSTKVNSQQETTPGTSAVPENHHHVSPQPASVPPPQNGQYQQHGMMTPNKAMASNWAHYQQPSMMTCSHYQTSPAYYQPDPHYPLPQYIPPLSTSSPDPIDSQDQHSEVPQAKTKVRNNVLPPHTLTSEENFYTWVKFYIRFLKNSNLGDIIPNDQGEIKRQMTYEEHAYIYNTFQAFAPFHLLPTWVKQILEINYADILTVLCKSVSKMQTNNQELKDWIALANLEYDGSTSADTFEITVSTIIQRLKENNINVSDRLACQLILKGLSGDFKYLRNQYRTKTNMKLSQLFAEIQLIYDENKIMNLNKPSQYKQHSEYKNVSRTSPNTTNTKVTTRNYHRTNSSKPRAAKAHNIATSSKFSRVNNDHINESTVSSQYLSDDNELSLRPATERI
SIO_010081: YBL100W-A
subclass of: SO_0000673
so part of: YBL100W-A
location: 29935..31251
location: region:29935-31251:1
so has part: feature:29935-31251:1:exon

NP_009451.1
type: Protein
SIO_000068: ncbiprotein

S000002148
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:29935-31251:1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty2 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 35271..35602
location: region:35271-35602:1
so has part: feature:35271-35602:1:region

S000006802
type: SGD
SIO_000068: sgd

position:35271:1
position: 35271
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:35271-35602:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 35604..35796
location: region:35604-35796:1
so has part: feature:35604-35796:1:region

S000006803
type: SGD
SIO_000068: sgd

position:35604:1
position: 35604
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:35796:1
position: 35796
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:35604-35796:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty4 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(35851..36221)
location: region:35851-36221:-1
so has part: feature:35851-36221:-1:region

S000006807
type: SGD
SIO_000068: sgd

position:35851:-1
position: 35851
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:36221:-1
position: 36221
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:35851-36221:-1:region

YNCB0002W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCB0002W
so part of: sequence
location: 36398..36488
location: region:36398-36488:1
so has part: feature:36398-36488:1:exon
subclass of: SO_0000663

852176
type: Gene
SIO_000068: ncbigene

position:36398:1
position: 36398
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:36488:1
position: 36488
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:36398-36488:1:exon

YNCB0002W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCB0002W
product: tRNA-Phe
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
experiment: EXISTENCE:direct assay:GO:0043022 ribosome binding [PMID:10024171]
note: Phenylalanine tRNA (tRNA-Phe), predicted by tRNAscan-SE analysis
SIO_010081: YNCB0002W
subclass of: SO_0000673
so part of: YNCB0002W
location: join(36398..36434,36453..36488)
location: region:36398-36488:1
so has part: feature:36398-36434:1:exon
so has part: feature:36453-36488:1:exon

S000006562
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:36398-36434:1:exon

position:36434:1
position: 36434
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:36453-36488:1:exon

position:36453:1
position: 36453
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YBL099W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ATP1
locus tag: YBL099W
so part of: sequence
location: <37053..>38690
location: region:37053-38690:1
so has part: feature:37053-38690:1:exon
subclass of: SO_0000010

852177
type: Gene
SIO_000068: ncbigene

position:37053:1
position: 37053
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:38690:1
position: 38690
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:37053-38690:1:exon

YBL099W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ATP1
locus tag: YBL099W
product: F1F0 ATP synthase subunit alpha
transcript id: NM_001178339.2
SIO_010081: YBL099W
subclass of: SO_0000673
so part of: YBL099W
location: <37053..>38690
location: region:37053-38690:1
so has part: feature:37053-38690:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:37053-38690:1:exon

YBL099W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ATP1
locus tag: YBL099W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:11502169|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005754 mitochondrial proton-transporting ATP synthase, catalytic core [PMID:15294286|PMID:17082766]
experiment: EXISTENCE:direct assay:GO:0015986 proton motive force-driven ATP synthesis [PMID:20691145]
experiment: EXISTENCE:direct assay:GO:0016887 ATP hydrolysis activity [PMID:18722382]
experiment: EXISTENCE:direct assay:GO:0042645 mitochondrial nucleoid [PMID:10869431]
experiment: EXISTENCE:direct assay:GO:0046933 proton-transporting ATP synthase activity, rotational mechanism [PMID:20691145]
experiment: EXISTENCE:mutant phenotype:GO:0005754 mitochondrial proton-transporting ATP synthase, catalytic core [PMID:2876995]
experiment: EXISTENCE:mutant phenotype:GO:0015986 proton motive force-driven ATP synthesis [PMID:2876995]
experiment: EXISTENCE:mutant phenotype:GO:0046933 proton-transporting ATP synthase activity, rotational mechanism [PMID:1827117|PMID:2876995]
note: Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase; which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; F1 translationally regulates ATP6 and ATP8 expression to achieve a balanced output of ATP synthase genes encoded in nucleus and mitochondria; phosphorylated; N-terminally propionylated in vivo
codon start: 1
product: F1F0 ATP synthase subunit alpha
translation: MLARTAAIRSLSRTLINSTKAARPAAAALASTRRLASTKAQPTEVSSILEERIKGVSDEANLNETGRVLAVGDGIARVFGLNNIQAEELVEFSSGVKGMALNLEPGQVGIVLFGSDRLVKEGELVKRTGNIVDVPVGPGLLGRVVDALGNPIDGKGPIDAAGRSRAQVKAPGILPRRSVHEPVQTGLKAVDALVPIGRGQRELIIGDRQTGKTAVALDTILNQKRWNNGSDESKKLYCVYVAVGQKRSTVAQLVQTLEQHDAMKYSIIVAATASEAAPLQYLAPFTAASIGEWFRDNGKHALIVYDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSEKEGSGSLTALPVIETQGGDVSAYIPTNVISITDGQIFLEAELFYKGIRPAINVGLSVSRVGSAAQVKALKQVAGSLKLFLAQYREVAAFAQFGSDLDASTKQTLVRGERLTQLLKQNQYSPLATEEQVPLIYAGVNGHLDGIELSRIGEFESSFLSYLKSNHNELLTEIREKGELSKELLASLKSATESFVATF
SIO_010081: YBL099W
subclass of: SO_0000673
so part of: YBL099W
location: 37053..38690
location: region:37053-38690:1
so has part: feature:37053-38690:1:exon

NP_009453.2
type: Protein
SIO_000068: ncbiprotein

S000000195
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:37053-38690:1:exon

YBL098W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: BNA4
locus tag: YBL098W
so part of: sequence
location: <39145..>40527
location: region:39145-40527:1
so has part: feature:39145-40527:1:exon
subclass of: SO_0000010

852179
type: Gene
SIO_000068: ncbigene

position:39145:1
position: 39145
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:40527:1
position: 40527
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:39145-40527:1:exon

YBL098W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: BNA4
locus tag: YBL098W
product: kynurenine 3-monooxygenase
transcript id: NM_001178338.1
SIO_010081: YBL098W
subclass of: SO_0000673
so part of: YBL098W
location: <39145..>40527
location: region:39145-40527:1
so has part: feature:39145-40527:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:39145-40527:1:exon

YBL098W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: BNA4
locus tag: YBL098W
EC number: 1.14.13.9
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095|PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005741 mitochondrial outer membrane [PMID:16407407]
experiment: EXISTENCE:direct assay:GO:0005777 peroxisome [PMID:36164978]
experiment: EXISTENCE:genetic interaction:GO:0034354 'de novo' NAD biosynthetic process from tryptophan [PMID:12062417]
experiment: EXISTENCE:mutant phenotype:GO:0004502 kynurenine 3-monooxygenase activity [PMID:15806102]
note: Kynurenine 3-monooxygenase; required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expression regulated by Hst1p; localizes to mitochondria and peroxisomes; putative therapeutic target for Huntington disease
codon start: 1
product: kynurenine 3-monooxygenase
translation: MSESVAIIGAGLVGCLAALAFSKEGYNVTLYDFRQDPRLDTTKNKNLKSINLAISARGIDALKSIDPDACEHILQDMIPMKGRMIHDLKGRQESQLYGLHGEAINSINRSVLNNSLLDELEKSTTELKFGHKLVKIEWTDDKQICHFAIGEDLKTPHTEKYDFVIGCDGAYSATRSQMQRKVEMDFSQEYMNLRYIELYIPPTEEFKPNYGGNFAIAPDHLHIWPRHKFMLIALANSDGSFTSTFFGSKDQISDLITSKSRVREFLIENFPDIINIMDLDDAVKRFITYPKESLVCVNCKPYDVPGGKAILLGDAAHAMVPFYGQGMNCGFEDVRILMALLKKHSGDRSRAFTEYTQTRHKDLVSITELAKRNYKEMSHDVTSKRFLLRKKLDALFSIIMKDKWIPLYTMISFRSDISYSRALERAGKQTRILKFLESLTLGMLSIGGYKLFKFLTRERS
SIO_010081: YBL098W
subclass of: SO_0000673
so part of: YBL098W
location: 39145..40527
location: region:39145-40527:1
so has part: feature:39145-40527:1:exon

NP_009454.1
type: Protein
SIO_000068: ncbiprotein

S000000194
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:39145-40527:1:exon

YBL097W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: BRN1
locus tag: YBL097W
so part of: sequence
location: <40831..>43095
location: region:40831-43095:1
so has part: feature:40831-43095:1:exon
subclass of: SO_0000010

852180
type: Gene
SIO_000068: ncbigene

position:40831:1
position: 40831
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:43095:1
position: 43095
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:40831-43095:1:exon

YBL097W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: BRN1
locus tag: YBL097W
product: condensin subunit BRN1
transcript id: NM_001178337.2
SIO_010081: YBL097W
subclass of: SO_0000673
so part of: YBL097W
location: <40831..>43095
location: region:40831-43095:1
so has part: feature:40831-43095:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:40831-43095:1:exon

YBL097W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: BRN1
locus tag: YBL097W
experiment: EXISTENCE:direct assay:GO:0000796 condensin complex [PMID:10811823]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:10749931]
experiment: EXISTENCE:genetic interaction:GO:0003682 chromatin binding [PMID:11864994]
experiment: EXISTENCE:mutant phenotype:GO:0000070 mitotic sister chromatid segregation [PMID:10749931]
experiment: EXISTENCE:mutant phenotype:GO:0007076 mitotic chromosome condensation [PMID:10749931|PMID:10811823|PMID:7698648]
experiment: EXISTENCE:mutant phenotype:GO:0070058 tRNA gene clustering [PMID:18708579]
note: Subunit of the condensin complex; required for chromosome condensation and for clustering of tRNA genes at the nucleolus; may influence multiple aspects of chromosome transmission
codon start: 1
product: condensin subunit BRN1
translation: MTTQLRYENNDDDERVEYNLFTNRSTMMANFEEWIKMATDNKINSRNSWNFALIDYFYDLDVLKDGENNINFQKASATLDGCIKIYSSRVDSVTTETGKLLSGLAQRKTNGASNGDDSNGGNGEGLGGDSDEANIEIDPLTGMPISNDPDVNNTRRRVYNRVLETTLVEFETIKMKELDQELIIDPLFKKALVDFDEGGAKSLLLNTLNIDNTARVIFDASIKDTQNVGQGKLQRKEEELIERDSLVDDENEPSQSLISTRNDSTVNDSVISAPSMEDEILSLGMDFIKFDQIAVCEISGSIEQLRNVVEDINQAKDFIENVNNRFDNFLTEEELQAAVPDNAEDDSDGFDMGMQQELCYPDENHDNTSHDEQDDDNVNSTTGSIFEKDLMAYFDENLNRNWRGREHWKVRNFKKANLVNKESDLLEETRTTIGDTTDKNTTDDKSMDTKKKHKQKKVLEIDFFKTDDSFEDKVFASKGRTKIDMPIKNRKNDTHYLLPDDFHFSTDRITRLFIKPGQKMSLFSHRKHTRGDVSSGLFEKSTVSANHSNNDIPTIADEHFWADNYERKEQEEKEKEQSKEVGDVVGGALDNPFEDDMDGVDFNQAFEGTDDNEEASVKLDLQDDEDHKFPIRENKVTYSRVSKKVDVRRLKKNVWRSINNLIQEHDSRKNREQSSNDSETHTEDESTKELKFSDIIQGISKMYSDDTLKDISTSFCFICLLHLANEHGLQITHTENYNDLIVNYEDLATTQAAS
SIO_010081: YBL097W
subclass of: SO_0000673
so part of: YBL097W
location: 40831..43095
location: region:40831-43095:1
so has part: feature:40831-43095:1:exon

NP_009455.3
type: Protein
SIO_000068: ncbiprotein

S000000193
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:40831-43095:1:exon

YBL095W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MRX3
locus tag: YBL095W
so part of: sequence
location: <43277..>44089
location: region:43277-44089:1
so has part: feature:43277-44089:1:exon
subclass of: SO_0000010

852181
type: Gene
SIO_000068: ncbigene

position:43277:1
position: 43277
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:44089:1
position: 44089
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:43277-44089:1:exon

YBL095W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MRX3
locus tag: YBL095W
product: Mrx3p
transcript id: NM_001178335.1
SIO_010081: YBL095W
subclass of: SO_0000673
so part of: YBL095W
location: <43277..>44089
location: region:43277-44089:1
so has part: feature:43277-44089:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:43277-44089:1:exon

YBL095W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MRX3
locus tag: YBL095W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005743 mitochondrial inner membrane [PMID:25546499]
note: Protein that associates with mitochondrial ribosome; likely functions in cristae junction formation; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
codon start: 1
product: Mrx3p
translation: MSRTIPFLFKLVNRAVILPTAGFTLGVGAFVKAWPDDAGVLSLNDPQTPAELISATKSRQPMELQRVDILAQIEKSEVYNKLAQDEKMHHVLFSEKIPSGHREYHVGQGLLFGKGKLEIDPLVFHDVNHGELTVIYHLGAELGNRDGNVHKGLLSLLLDEALCYCGFPLLPSKRGVTARLSLEFFEDIPVDTTIILKANVKEIKGRKCIIEGHLEQFPLEVSSRNGTRSWNLPHIWGFNHKQEMAKKFAKANCILVEPTWFKYFKWLDMF
SIO_010081: YBL095W
subclass of: SO_0000673
so part of: YBL095W
location: 43277..44089
location: region:43277-44089:1
so has part: feature:43277-44089:1:exon

NP_009457.1
type: Protein
SIO_000068: ncbiprotein

S000000191
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:43277-44089:1:exon

YBL093C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MED19
alternative label: NUT3
alternative label: RMR1
alternative label: SSN7
alternative label: SSX2
gene: ROX3
locus tag: YBL093C
gene synonym: MED19; NUT3; RMR1; SSN7; SSX2
so part of: sequence
location: complement(<44256..>44918)
location: region:44256-44918:-1
so has part: feature:44256-44918:-1:exon
subclass of: SO_0000010

852184
type: Gene
SIO_000068: ncbigene

position:44256:-1
position: 44256
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:44918:-1
position: 44918
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:44256-44918:-1:exon

YBL093C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MED19
alternative label: NUT3
alternative label: RMR1
alternative label: SSN7
alternative label: SSX2
gene: ROX3
locus tag: YBL093C
gene synonym: MED19; NUT3; RMR1; SSN7; SSX2
product: Rox3p
transcript id: NM_001178333.1
SIO_010081: YBL093C
subclass of: SO_0000673
so part of: YBL093C
location: complement(<44256..>44918)
location: region:44256-44918:-1
so has part: feature:44256-44918:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:44256-44918:-1:exon

YBL093C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MED19
alternative label: NUT3
alternative label: RMR1
alternative label: SSN7
alternative label: SSX2
gene: ROX3
locus tag: YBL093C
gene synonym: MED19; NUT3; RMR1; SSN7; SSX2
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:1656237]
experiment: EXISTENCE:direct assay:GO:0070847 core mediator complex [PMID:9891034]
experiment: EXISTENCE:mutant phenotype:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:16452140]
experiment: EXISTENCE:mutant phenotype:GO:0001113 transcription open complex formation at RNA polymerase II promoter [PMID:20048049]
experiment: EXISTENCE:mutant phenotype:GO:0003713 transcription coactivator activity [PMID:15831453]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:16452140]
experiment: EXISTENCE:mutant phenotype:GO:0051123 RNA polymerase II preinitiation complex assembly [PMID:15964818]
note: Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme
codon start: 1
product: Rox3p
translation: MASRVDETTVPSYYYYVDPETTYTYQQPNPLQDLISVYGLDDISRQVARTNLDGTKAVKLRKSYKNQIADLSGKFSTIPTRENGKGGQIAHILFQNNPDMMIQPPQQGQNMSEQQWREQLRNRDIALFQPPNFDWDLCSSVLSQFERSYPSEFANQNQGGAQAPFDIDDLAFDLDGTGKSQSGSNSGNNSKKRKNKSSGSSMATPTHSDSHEDMKRRRLE
SIO_010081: YBL093C
subclass of: SO_0000673
so part of: YBL093C
location: complement(44256..44918)
location: region:44256-44918:-1
so has part: feature:44256-44918:-1:exon

NP_009459.1
type: Protein
SIO_000068: ncbiprotein

S000000189
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:44256-44918:-1:exon

YBL092W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RPL32
locus tag: YBL092W
so part of: sequence
location: <45978..>46370
location: region:45978-46370:1
so has part: feature:45978-46370:1:exon
subclass of: SO_0000010

852185
type: Gene
SIO_000068: ncbigene

position:45978:1
position: 45978
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:46370:1
position: 46370
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:45978-46370:1:exon

YBL092W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RPL32
locus tag: YBL092W
product: ribosomal 60S subunit protein L32
transcript id: NM_001178332.1
SIO_010081: YBL092W
subclass of: SO_0000673
so part of: YBL092W
location: <45978..>46370
location: region:45978-46370:1
so has part: feature:45978-46370:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:45978-46370:1:exon

YBL092W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RPL32
locus tag: YBL092W
experiment: EXISTENCE:curator inference:GO:0002181 cytoplasmic translation [PMID:11983894]
experiment: EXISTENCE:curator inference:GO:0003735 structural constituent of ribosome [PMID:11983894]
experiment: EXISTENCE:direct assay:GO:0022625 cytosolic large ribosomal subunit [PMID:11983894]
note: Ribosomal 60S subunit protein L32; overexpression disrupts telomeric silencing; homologous to mammalian ribosomal protein L32, no bacterial homolog
codon start: 1
product: ribosomal 60S subunit protein L32
translation: MASLPHPKIVKKHTKKFKRHHSDRYHRVAENWRKQKGIDSVVRRRFRGNISQPKIGYGSNKKTKFLSPSGHKTFLVANVKDLETLTMHTKTYAAEIAHNISAKNRVVILARAKALGIKVTNPKGRLALEA
SIO_010081: YBL092W
subclass of: SO_0000673
so part of: YBL092W
location: 45978..46370
location: region:45978-46370:1
so has part: feature:45978-46370:1:exon

NP_009460.1
type: Protein
SIO_000068: ncbiprotein

S000000188
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:45978-46370:1:exon

YBL091C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SCS22
locus tag: YBL091C-A
so part of: sequence
location: complement(<46565..>47180)
location: region:46565-47180:-1
so has part: feature:46565-47180:-1:exon
subclass of: SO_0000010

852186
type: Gene
SIO_000068: ncbigene

position:46565:-1
position: 46565
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:47180:-1
position: 47180
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:46565-47180:-1:exon

YBL091C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SCS22
locus tag: YBL091C-A
product: phospholipid metabolism-regulating protein SCS22
transcript id: NM_001184321.1
SIO_010081: YBL091C-A
subclass of: SO_0000673
so part of: YBL091C-A
location: complement(join(<46565..47058,47147..>47180))
location: region:46565-47180:-1
so has part: feature:47147-47180:-1:exon
so has part: feature:46565-47058:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:47147-47180:-1:exon

position:47147:-1
position: 47147
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:46565-47058:-1:exon

position:47058:-1
position: 47058
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YBL091C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SCS22
locus tag: YBL091C-A
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0008654 phospholipid biosynthetic process [PMID:15668246]
experiment: EXISTENCE:genetic interaction:GO:0060304 regulation of phosphatidylinositol dephosphorylation [PMID:23237950]
experiment: EXISTENCE:genetic interaction:GO:0061709 reticulophagy [PMID:35101986]
experiment: EXISTENCE:genetic interaction:GO:0090158 endoplasmic reticulum membrane organization [PMID:23237950]
note: Protein involved in regulation of phospholipid metabolism; one of 6 proteins (Ist2p, Scs2p, Scs22p, Tcb1p, Tcb2p, Tcb3p) that connect the ER and plasma membrane (PM); regulates PM PI4P levels by controlling access of the Sac1p phosphatase to its substrate, PI4P; human VAP homolog; similar to D. melanogaster inturned protein; SWAT-GFP and mCherry fusion proteins localize to the cytosol; SCS22 has a paralog, SCS2, that arose from the whole genome duplication
codon start: 1
product: phospholipid metabolism-regulating protein SCS22
translation: MRIVPEKLVFKAPLNKQSTEYIKLENDGEKRVIFKVRTSAPTKYCVRPNVAIIGAHESVNVQIVFLGLPKSTADDEMDQKRDKFLIVTLPIPAAYQNVEDGELLSDWPNLEEQYKDDIVFKKIKIFHSVLPKRKPSGNHDAESARAPSAGNGQSLSSRALLIITVIALLVGWIYY
SIO_010081: YBL091C-A
subclass of: SO_0000673
so part of: YBL091C-A
location: complement(join(46565..47058,47147..47180))
location: region:46565-47180:-1
so has part: feature:47147-47180:-1:exon
so has part: feature:46565-47058:-1:exon

NP_009461.2
type: Protein
SIO_000068: ncbiprotein

S000007228
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:47147-47180:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:46565-47058:-1:exon

YBL091C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MAP2
locus tag: YBL091C
so part of: sequence
location: complement(<47363..>48628)
location: region:47363-48628:-1
so has part: feature:47363-48628:-1:exon
subclass of: SO_0000010

852187
type: Gene
SIO_000068: ncbigene

position:47363:-1
position: 47363
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:48628:-1
position: 48628
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:47363-48628:-1:exon

YBL091C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MAP2
locus tag: YBL091C
product: methionine aminopeptidase
transcript id: NM_001178331.2
SIO_010081: YBL091C
subclass of: SO_0000673
so part of: YBL091C
location: complement(<47363..>48628)
location: region:47363-48628:-1
so has part: feature:47363-48628:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:47363-48628:-1:exon

YBL091C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MAP2
locus tag: YBL091C
EC number: 3.4.11.18
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:genetic interaction:GO:0070006 metalloaminopeptidase activity [PMID:8618900]
experiment: EXISTENCE:mutant phenotype:GO:0035551 protein initiator methionine removal involved in protein maturation [PMID:11811952]
note: Methionine aminopeptidase; catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map1p
codon start: 1
product: methionine aminopeptidase
translation: MTDAEIENSPASDLKELNLENEGVEQQDQAKADESDPVESKKKKNKKKKKKKSNVKKIELLFPDGKYPEGAWMDYHQDFNLQRTTDEESRYLKRDLERAEHWNDVRKGAEIHRRVRRAIKDRIVPGMKLMDIADMIENTTRKYTGAENLLAMEDPKSQGIGFPTGLSLNHCAAHFTPNAGDKTVLKYEDVMKVDYGVQVNGNIIDSAFTVSFDPQYDNLLAAVKDATYTGIKEAGIDVRLTDIGEAIQEVMESYEVEINGETYQVKPCRNLCGHSIAPYRIHGGKSVPIVKNGDTTKMEEGEHFAIETFGSTGRGYVTAGGEVSHYARSAEDHQVMPTLDSAKNLLKTIDRNFGTLPFCRRYLDRLGQEKYLFALNNLVRHGLVQDYPPLNDIPGSYTAQFEHTILLHAHKKEVVSKGDDY
SIO_010081: YBL091C
subclass of: SO_0000673
so part of: YBL091C
location: complement(47363..48628)
location: region:47363-48628:-1
so has part: feature:47363-48628:-1:exon

NP_009462.2
type: Protein
SIO_000068: ncbiprotein

S000000187
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:47363-48628:-1:exon

YBL090W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: bS21m
alternative label: MRP50
gene: MRP21
locus tag: YBL090W
gene synonym: bS21m; MRP50
so part of: sequence
location: <48825..>49358
location: region:48825-49358:1
so has part: feature:48825-49358:1:exon
subclass of: SO_0000010

852188
type: Gene
SIO_000068: ncbigene

position:48825:1
position: 48825
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:49358:1
position: 49358
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:48825-49358:1:exon

YBL090W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: bS21m
alternative label: MRP50
gene: MRP21
locus tag: YBL090W
gene synonym: bS21m; MRP50
product: mitochondrial 37S ribosomal protein MRP21
transcript id: NM_001178330.1
SIO_010081: YBL090W
subclass of: SO_0000673
so part of: YBL090W
location: <48825..>49358
location: region:48825-49358:1
so has part: feature:48825-49358:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:48825-49358:1:exon

YBL090W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: bS21m
alternative label: MRP50
gene: MRP21
locus tag: YBL090W
gene synonym: bS21m; MRP50
experiment: EXISTENCE:direct assay:GO:0003735 structural constituent of ribosome [PMID:9528754]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005763 mitochondrial small ribosomal subunit [PMID:9528754]
experiment: EXISTENCE:genetic interaction:GO:0070124 mitochondrial translational initiation [PMID:9528754]
experiment: EXISTENCE:mutant phenotype:GO:0032543 mitochondrial translation [PMID:9528754]
note: Mitochondrial ribosomal protein of the small subunit; MRP21 exhibits genetic interactions with mutations in the COX2 and COX3 mRNA 5'-untranslated leader sequences
codon start: 1
product: mitochondrial 37S ribosomal protein MRP21
translation: MLKSTLRLSRISLRRGFTTIDCLRQQNSDIDKIILNPIKLAQGSNSDRGQTSKSKTDNADILSMEIPVDMMQSAGRINKRELLSEAEIARSSVENAQMRFNSGKSIIVNKNNPAESFKRLNRIMFENNIPGDKRSQRFYMKPGKVAELKRSQRHRKEFMMGFKRLIEIVKDAKRKGY
SIO_010081: YBL090W
subclass of: SO_0000673
so part of: YBL090W
location: 48825..49358
location: region:48825-49358:1
so has part: feature:48825-49358:1:exon

NP_009463.1
type: Protein
SIO_000068: ncbiprotein

S000000186
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:48825-49358:1:exon

YBL089W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: AVT5
locus tag: YBL089W
so part of: sequence
location: <49574..>50953
location: region:49574-50953:1
so has part: feature:49574-50953:1:exon
subclass of: SO_0000010

852189
type: Gene
SIO_000068: ncbigene

position:49574:1
position: 49574
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:50953:1
position: 50953
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:49574-50953:1:exon

YBL089W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: AVT5
locus tag: YBL089W
product: amino acid transporter
transcript id: NM_001178329.1
SIO_010081: YBL089W
subclass of: SO_0000673
so part of: YBL089W
location: <49574..>50953
location: region:49574-50953:1
so has part: feature:49574-50953:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:49574-50953:1:exon

YBL089W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: AVT5
locus tag: YBL089W
note: Putative transporter; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters; AVT5 has a paralog, AVT6, that arose from the whole genome duplication
codon start: 1
product: amino acid transporter
translation: MPSNVRSGVLTLLHTACGAGVLAMPFAFKPFGLMPGLITLTFCGICSLCGLLLQTRIAKYVPKSENASFAKLTQLINPSISVVFDFAIAVKCFGVGVSYLIIVGDLVPQIVQSIFYRNDDNMSGSQEHHMFLDRRLYITLIIVFVISPLCFKRSLNSLRYASMIAIVSVAYLSGLIIYHFVNRHQLERGQVYFMVPHGDSQSHSPLTTLPIFVFAYTCHHNMFSVINEQVDKSFKVIRRIPIFAIVLAYFLYIIIGGTGYMTFGENIVGNILTLYPNSISTTIGRLAMLLLVMLAFPLQCHPCRSSVKNIIIFIENFRKGKLYDNRASFIPLDNFNSEDPQEAPTQQNNEEPNLRSESLRHINIITLCILLFSYLLAISITSLAKVLAIVGATGSTSISFILPGLFGYKLIGSEFTGTNERVPTSIKIFKYLSLSLFIWGIAVMVASLSAIVFLGTSSH
SIO_010081: YBL089W
subclass of: SO_0000673
so part of: YBL089W
location: 49574..50953
location: region:49574-50953:1
so has part: feature:49574-50953:1:exon

NP_009464.2
type: Protein
SIO_000068: ncbiprotein

S000000185
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:49574-50953:1:exon

YBL088C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TEL1
locus tag: YBL088C
so part of: sequence
location: complement(<51019..>59382)
location: region:51019-59382:-1
so has part: feature:51019-59382:-1:exon
subclass of: SO_0000010

852190
type: Gene
SIO_000068: ncbigene

position:51019:-1
position: 51019
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:59382:-1
position: 59382
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:51019-59382:-1:exon

YBL088C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TEL1
locus tag: YBL088C
product: DNA-binding protein kinase TEL1
transcript id: NM_001178328.2
SIO_010081: YBL088C
subclass of: SO_0000673
so part of: YBL088C
location: complement(<51019..>59382)
location: region:51019-59382:-1
so has part: feature:51019-59382:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:51019-59382:-1:exon

YBL088C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TEL1
locus tag: YBL088C
EC number: 2.7.11.1
experiment: EXISTENCE:curator inference:GO:0005634 nucleus [PMID:3513174|PMID:7569949]
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:11095737]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0042162 telomeric DNA binding [PMID:17656141]
experiment: EXISTENCE:genetic interaction:GO:0000723 telomere maintenance [PMID:8604297]
experiment: EXISTENCE:genetic interaction:GO:0006281 DNA repair [PMID:25628362]
experiment: EXISTENCE:genetic interaction:GO:0006302 double-strand break repair [PMID:17347674]
experiment: EXISTENCE:mutant phenotype:GO:0000723 telomere maintenance [PMID:3513174|PMID:8604297]
experiment: EXISTENCE:mutant phenotype:GO:0004674 protein serine/threonine kinase activity [PMID:25329891]
experiment: EXISTENCE:mutant phenotype:GO:0006302 double-strand break repair [PMID:17347674]
experiment: EXISTENCE:mutant phenotype:GO:0006974 cellular response to DNA damage stimulus [PMID:17347674]
experiment: EXISTENCE:mutant phenotype:GO:0042770 signal transduction in response to DNA damage [PMID:17693258]
note: Protein kinase primarily involved in telomere length regulation; contributes to cell cycle checkpoint control in response to DNA damage; acts with Red1p and Mec1p to promote interhomolog recombination by phosphorylation of Hop1; functionally redundant with Mec1p; regulates P-body formation induced by replication stress; homolog of human ataxia-telangiectasia mutated (ATM) gene
codon start: 1
product: DNA-binding protein kinase TEL1
translation: MEDHGIVETLNFLSSTKIKERNNALDELTTILKEDPERIPTKALSTTAEALVELLASEHTKYCDLLRNLTVSTTNKLSLSENRLSTISYVLRLFVEKSCERFKVKTLKLLLAVVPELMVKDGSKSLLDAVSVHLSFALDALIKSDPFKLKFMIHQWISLVDKICEYFQSQMKLSMVDKTLTNFISILLNLLALDTVGIFQVTRTITWTVIDFLRLSKKENGNTRLIMSLINQLILKCHCFSVIDTLMLIKEAWSYNLTIGCTSNELVQDQLSLFDVMSSELMNHKLPYMIGQENYVEELRSESLVSLYREYILLRLSNYKPQLFTVNHVEFSYIRGSRDKNSWFALPDFRLRDRGGRSVWLKILGITKSLLTYFALNRKNENYSLLFKRRKCDSDIPSILRISDDMDTFLIHLLEENSSHEFEVLGLQLCSFYGTLQDFTKSFAEQLKELLFSKFEKIQCFNWVCFSFIPLLSQKECELSNGDMARLFKVCLPLVKSNESCQLSCLLLANSIKFSKQLLSDEKTINQIYDLYELSDILGPILVTNESFMLWGYLQYVGKDFQSMNGISSADRIFEWLKSKWNQLRGTDAKQDQFCNFISWLGNKYDPENPFNDKKGEGANPVSLCWDESHKIWQHFQEQREFLLGVKPEEKSECFNTPFFNLPKVSLDLTRYNEILYRLLENIESDAFSSPLQKFTWVAKLIQIVDNLCGDSTFSEFIAAYKRTTLITIPQLSFDSQNSYQSFFEEVLSIRTINVDHLVLDKINMKEIVNDFIRMQKNKSQTGTSAINYFEASSEDTTQNNSPYTIGGRFQKPLHSTIDKAVRAYLWSSRNKSISERLVAILEFSDCVSTDVFISYLGTVCQWLKQAIGEKSSYNKILEEFTEVLGEKLLCNHYSSSNQAMLLLTSYIEAIRPQWLSYPEQPLNSDCNDILDWIISRFEDNSFTGVAPTVNLSMLLLSLLQNHDLSHGSIRGGKQRVFATFIKCLQKLDSSNIINIMNSISSYMAQVSYKNQSIIFYEIKSLFGPPQQSIEKSAFYSLAMSMLSLVSYPSLVFSLEDMMTYSGFNHTRAFIQQALNKITVAFRYQNLTELFEYCKFDLIMYWFNRTKVPTSKLEKEWDISLFGFADIHEFLGRYFVEISAIYFSQGFNQKWILDMLHAITGNGDAYLVDNSYYLCIPLAFISGGVNELIFDILPQISGKTTVKYHKKYRLLMLKWIIRFTDLGSLTELRSTVEKLFPTSYLSPYLFENSSVSMRYQYPLHIPLALGATLVQTQFAHEKNNTHEFKLLFLSVITDLEKTSTYIGKLRCARELKYLFVLYENVLVKSSTLNFIIIRLSKFLIDTQIHDEVITIFSSLLNLADKNTFEIEPSLPNLFCKIFIYLRENKQLSPSFQQAIKLLEHRDLIKIKTWKYCLDAIFGNIVQDDIYENTELLDASDCGVDDVVLVSLLFSYARRPVASKIGCSLSKAAAINILKHHVPKEYLSKNFKLWFAALSRRILQQEVQRERSTNFNNEVHLKNFEMVFRHPEQPHMIYQRISTFNKEAELYDSTEVFFISECILTYLVGYSIGNSESEFCFRDNIMNENKDKVAPLDKDVLNAIYPLANNFGMESFICDTYLSVNEPYNCWLSKFARSLIHQISFNIPPIVCLYPLCKGSTAFCELVLTDLFFLSTTYDPKSCLNWSNRIFTQIAMLLHVKDSEIKLKMLFNVIKMIRMGSRCKERNCLRIYSSLDLQEICQISLKIKEFKFGYLLFEEMNMPNIREMNINTLQKIYECINDGDFLAGLPVPHSIEGVLNSINRIDSDTWKRFLFNNADFDANYTTSLEEEKESLIKATEDSGFYGLTSLLESRLSGSSDVYKWNLELGDWKLLTPKVVDSKAKGLYYAIKNLPQDVGFAEKSLEKSLLTIFDSRQHFISQTEWMDTLNAIIEFIKIAAIPQDVTSFPQTLMSIMKADKERLNTIDFYDHKTTLKSRHTLMNVLSRNSLDENVKCSKYLRLGSII…
SIO_010081: YBL088C
subclass of: SO_0000673
so part of: YBL088C
location: complement(51019..59382)
location: region:51019-59382:-1
so has part: feature:51019-59382:-1:exon

NP_009465.2
type: Protein
SIO_000068: ncbiprotein

S000000184
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:51019-59382:-1:exon

YBL087C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RPL23A
locus tag: YBL087C
so part of: sequence
location: complement(<59822..>60739)
location: region:59822-60739:-1
so has part: feature:59822-60739:-1:exon
subclass of: SO_0000010

852191
type: Gene
SIO_000068: ncbigene

position:59822:-1
position: 59822
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:60739:-1
position: 60739
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:59822-60739:-1:exon

YBL087C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RPL23A
locus tag: YBL087C
product: ribosomal 60S subunit protein L23A
transcript id: NM_001178327.1
SIO_010081: YBL087C
subclass of: SO_0000673
so part of: YBL087C
location: complement(join(<59822..60193,60698..>60739))
location: region:59822-60739:-1
so has part: feature:60698-60739:-1:exon
so has part: feature:59822-60193:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:60698-60739:-1:exon

position:60698:-1
position: 60698
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:59822-60193:-1:exon

position:60193:-1
position: 60193
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YBL087C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RPL23A
locus tag: YBL087C
experiment: EXISTENCE:curator inference:GO:0002181 cytoplasmic translation [PMID:11983894]
experiment: EXISTENCE:curator inference:GO:0003735 structural constituent of ribosome [PMID:11983894]
experiment: EXISTENCE:direct assay:GO:0022625 cytosolic large ribosomal subunit [PMID:11983894]
note: Ribosomal 60S subunit protein L23A; homologous to mammalian ribosomal protein L23 and bacterial L14; RPL23A has a paralog, RPL23B, that arose from the whole genome duplication
codon start: 1
product: ribosomal 60S subunit protein L23A
translation: MSGNGAQGTKFRISLGLPVGAIMNCADNSGARNLYIIAVKGSGSRLNRLPAASLGDMVMATVKKGKPELRKKVMPAIVVRQAKSWRRRDGVFLYFEDNAGVIANPKGEMKGSAITGPVGKECADLWPRVASNSGVVV
SIO_010081: YBL087C
subclass of: SO_0000673
so part of: YBL087C
location: complement(join(59822..60193,60698..60739))
location: region:59822-60739:-1
so has part: feature:60698-60739:-1:exon
so has part: feature:59822-60193:-1:exon

NP_009466.1
type: Protein
SIO_000068: ncbiprotein

S000000183
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:60698-60739:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:59822-60193:-1:exon

YBL086C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBL086C
so part of: sequence
location: complement(<61202..>62602)
location: region:61202-62602:-1
so has part: feature:61202-62602:-1:exon
subclass of: SO_0000010

852192
type: Gene
SIO_000068: ncbigene

position:61202:-1
position: 61202
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:62602:-1
position: 62602
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:61202-62602:-1:exon

YBL086C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBL086C
product: uncharacterized protein
transcript id: NM_001178326.1
SIO_010081: YBL086C
subclass of: SO_0000673
so part of: YBL086C
location: complement(<61202..>62602)
location: region:61202-62602:-1
so has part: feature:61202-62602:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:61202-62602:-1:exon

YBL086C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBL086C
note: hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
codon start: 1
product: uncharacterized protein
translation: MPFNHNSKAKRPKFLLDLQIKELVNIPQSSGYCYTKWRLKDGTGTSGHKVALDGEHQTTSTQSRGTTKHVHVQHHRAQWNYSLDKPILVKLHLDKNGRFLKKILVLDVFFEFADANSSLTSSSSPNGKVKKTTYANATALTATGNNSYSQKITGKLLLGTVDIDITEYVKEDETPTTNRFLLKHSKVNSIINVSLQLKLVRGSYEDFNISKSFTNGQLANYRPGINTILDNTSELSSPTSTTNQMSPKNTFSNFNGIGTTVAKPGTNATGNSTSIKSPTSTNHKSSEMTTKPGLSTTISSSMSPLIESLYQKTFKLPWDPRPGEFTPRECVEDILQGGNGWAKNEKGINLIDLQALRLNEMEEEYYNPNYGNNLGNKASSWPPNPSDDGYSTMGKREYLEKKQNWSHMSRAQRAKLRTHNDEDNENTANDKGSDKDNNSVEDNNPTDFLTDRIRENKNWSIITPSG
SIO_010081: YBL086C
subclass of: SO_0000673
so part of: YBL086C
location: complement(61202..62602)
location: region:61202-62602:-1
so has part: feature:61202-62602:-1:exon

NP_009467.1
type: Protein
SIO_000068: ncbiprotein

S000000182
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:61202-62602:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS202; Autonomously Replicating Sequence
so part of: sequence
location: 63259..63381
location: region:63259-63381:1
so has part: feature:63259-63381:1:region

S000118344
type: SGD
SIO_000068: sgd

position:63259:1
position: 63259
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:63381:1
position: 63381
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:63259-63381:1:region

YBL085W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: BOB1
alternative label: GIN7
gene: BOI1
locus tag: YBL085W
gene synonym: BOB1; GIN7
so part of: sequence
location: <63876..>66818
location: region:63876-66818:1
so has part: feature:63876-66818:1:exon
subclass of: SO_0000010

852193
type: Gene
SIO_000068: ncbigene

position:63876:1
position: 63876
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:66818:1
position: 66818
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:63876-66818:1:exon

YBL085W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: BOB1
alternative label: GIN7
gene: BOI1
locus tag: YBL085W
gene synonym: BOB1; GIN7
product: Boi1p
transcript id: NM_001178325.1
SIO_010081: YBL085W
subclass of: SO_0000673
so part of: YBL085W
location: <63876..>66818
location: region:63876-66818:1
so has part: feature:63876-66818:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:63876-66818:1:exon

YBL085W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: BOB1
alternative label: GIN7
gene: BOI1
locus tag: YBL085W
gene synonym: BOB1; GIN7
experiment: EXISTENCE:direct assay:GO:0005543 phospholipid binding [PMID:12097146|PMID:28751498]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005933 cellular bud [PMID:12097146]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:12097146|PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0030427 site of polarized growth [PMID:12097146]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:19053807]
experiment: EXISTENCE:genetic interaction:GO:0000920 septum digestion after cytokinesis [PMID:16615892]
experiment: EXISTENCE:genetic interaction:GO:0007015 actin filament organization [PMID:31964708]
experiment: EXISTENCE:genetic interaction:GO:0007118 budding cell apical bud growth [PMID:17417630]
experiment: EXISTENCE:mutant phenotype:GO:0099500 vesicle fusion to plasma membrane [PMID:28751498]
note: Protein involved in polar growth, functionally redundant with Boi2p; required for fusion of secretory vesicles with plasma membrane at sites of polarized growth; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain; relocalizes from bud neck to cytoplasm upon DNA replication stress; BOI1 has a paralog, BOI2, that arose from the whole genome duplication
codon start: 1
product: Boi1p
translation: MSLEGNTLGKGAKSFPLYIAVNQYSKRMEDELNMKPGDKIKVITDDGEYNDGWYYGRNLRTKEEGLYPAVFTKRIAIEKPENLHKSPTQESGNSGVKYGNLNDSASNIGKVSSHQQENRYTSLKSTMSDIDKALEELRSGSVEQEVSKSPTRVPEVSTPQLQDEQTLIQEKTRNEENTTHDSLFSSTADLNLSSESLKNISKSNISTKSLEPSSESVRQLDLKMAKSWSPEEVTDYFSLVGFDQSTCNKFKEHQVSGKILLELELEHLKELEINSFGIRFQIFKEIRNIKSAIDSSSNKLDADYSTFAFENQAAQLMPAATVNRDEIQQQISSKCNKLSSESSDRKSSSVTTELQRPSSVVVNPNFKLHDPAEQILDMTEVPNLFADKDIFESPGRAPKPPSYPSPVQPPQSPSFNNRYTNNNARFPPQTTYPPKNKNPTVYSNGLIPNSSTSSDNSTGKFKFPAMNGHDSNSRKTTLTSATIPSINTVNTDESLPAISNISSNATSHHPNRNSVVYNNHKRTESGSSFVDLFNRISMLSPVKSSFDEEETKQPSKASRAVFDSARRKSSYGHSRDASLSEMKKHRRNSSILSFFSSKSQSNPTSPTKQTFTIDPAKMTSHSRSQSNSYSHARSQSYSHSRKHSLVTSPLKTSLSPINSKSNIALAHSETPTSSNNKEAVSQPSEGKHKHKHKHKSKHKHKNSSSKDGSSEEKSKKKLFSSTKESFVGSKEFKRSPSELTQKSTKSILPRSNAKKQQTSAFTEGIRSITAKESMQTADCSGWMSKKGTGAMGTWKQRFFTLHGTRLSYFTNTNDEKERGLIDITAHRVLPASDDDRLISLYAASLGKGKYCFKLVPPQPGSKKGLTFTEPRVHYFAVENKSEMKAWLSAIIKATIDIDTSVPVISSYATPTIPLSKAQTLLEEARLQTQLRDAEEEEGRDQFGWDDTQNKRNSNYPIEQDQFETSDYLESSAFEYPGGRL
SIO_010081: YBL085W
subclass of: SO_0000673
so part of: YBL085W
location: 63876..66818
location: region:63876-66818:1
so has part: feature:63876-66818:1:exon

NP_009468.1
type: Protein
SIO_000068: ncbiprotein

S000000181
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:63876-66818:1:exon

YBL084C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: APC3
alternative label: SNB1
gene: CDC27
locus tag: YBL084C
gene synonym: APC3; SNB1
so part of: sequence
location: complement(<67169..>69445)
location: region:67169-69445:-1
so has part: feature:67169-69445:-1:exon
subclass of: SO_0000010

852194
type: Gene
SIO_000068: ncbigene

position:67169:-1
position: 67169
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:69445:-1
position: 69445
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:67169-69445:-1:exon

YBL084C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: APC3
alternative label: SNB1
gene: CDC27
locus tag: YBL084C
gene synonym: APC3; SNB1
product: anaphase promoting complex subunit CDC27
transcript id: NM_001178324.2
SIO_010081: YBL084C
subclass of: SO_0000673
so part of: YBL084C
location: complement(<67169..>69445)
location: region:67169-69445:-1
so has part: feature:67169-69445:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:67169-69445:-1:exon

YBL084C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: APC3
alternative label: SNB1
gene: CDC27
locus tag: YBL084C
gene synonym: APC3; SNB1
experiment: EXISTENCE:direct assay:GO:0005680 anaphase-promoting complex [PMID:9469814]
experiment: EXISTENCE:direct assay:GO:0016567 protein ubiquitination [PMID:16481473]
experiment: EXISTENCE:direct assay:GO:0031145 anaphase-promoting complex-dependent catabolic process [PMID:8895471]
experiment: EXISTENCE:direct assay:GO:0034399 nuclear periphery [PMID:25817432]
experiment: EXISTENCE:mutant phenotype:GO:0016567 protein ubiquitination [PMID:16481473]
experiment: EXISTENCE:mutant phenotype:GO:0031145 anaphase-promoting complex-dependent catabolic process [PMID:16481473]
experiment: EXISTENCE:mutant phenotype:GO:0061630 ubiquitin protein ligase activity [PMID:16481473]
note: Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C); APC/C is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition
codon start: 1
product: anaphase promoting complex subunit CDC27
translation: MAVNPELAPFTLSRGIPSFDDQALSTIIQLQDCIQQAIQQLNYSTAEFLAELLYAECSILDKSSVYWSDAVYLYALSLFLNKSYHTAFQISKEFKEYHLGIAYIFGRCALQLSQGVNEAILTLLSIINVFSSNSSNTRINMVLNSNLVHIPDLATLNCLLGNLYMKLDHSKEGAFYHSEALAINPYLWESYEAICKMRATVDLKRVFFDIAGKKSNSHNNNAASSFPSTSLSHFEPRSQPSLYSKTNKNGNNNINNNVNTLFQSSNSPPSTSASSFSSIQHFSRSQQQQANTSIRTCQNKNTQTPKNPAINSKTSSALPNNISMNLVSPSSKQPTISSLAKVYNRNKLLTTPPSKLLNNDRNHQNNNNNNNNNNNNNNNNNNNNNNNNIINKTTFKTPRNLYSSTGRLTTSKKNPRSLIISNSILTSDYSITLPEIMYNFALILRSSSQYNSFKAIRLFESQIPSHIKDTMPWCLVQLGKLHFEIINYDMSLKYFNRLKDLQPARVKDMEIFSTLLWHLHDKVKSSNLANGLMDTMPNKPETWCCIGNLLSLQKDHDAAIKAFEKATQLDPNFAYAYTLQGHEHSSNDSSDSAKTCYRKALACDPQHYNAYYGLGTSAMKLGQYEEALLYFEKARSINPVNVVLICCCGGSLEKLGYKEKALQYYELACHLQPTSSLSKYKMGQLLYSMTRYNVALQTFEELVKLVPDDATAHYLLGQTYRIVGRKKDAIKELTVAMNLDPKGNQVIIDELQKCHMQE
SIO_010081: YBL084C
subclass of: SO_0000673
so part of: YBL084C
location: complement(67169..69445)
location: region:67169-69445:-1
so has part: feature:67169-69445:-1:exon

NP_009469.2
type: Protein
SIO_000068: ncbiprotein

S000000180
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:67169-69445:-1:exon

YBL082C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RHK1
gene: ALG3
locus tag: YBL082C
gene synonym: RHK1
so part of: sequence
location: complement(<69751..>71127)
location: region:69751-71127:-1
so has part: feature:69751-71127:-1:exon
subclass of: SO_0000010

852196
type: Gene
SIO_000068: ncbigene

position:69751:-1
position: 69751
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:71127:-1
position: 71127
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:69751-71127:-1:exon

YBL082C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RHK1
gene: ALG3
locus tag: YBL082C
gene synonym: RHK1
product: dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase
transcript id: NM_001178322.1
SIO_010081: YBL082C
subclass of: SO_0000673
so part of: YBL082C
location: complement(<69751..>71127)
location: region:69751-71127:-1
so has part: feature:69751-71127:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:69751-71127:-1:exon

YBL082C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RHK1
gene: ALG3
locus tag: YBL082C
gene synonym: RHK1
EC number: 2.4.1.258
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0006490 oligosaccharide-lipid intermediate biosynthetic process [PMID:11308030]
experiment: EXISTENCE:direct assay:GO:0052925 dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity [PMID:11308030]
experiment: EXISTENCE:mutant phenotype:GO:0005783 endoplasmic reticulum [PMID:8842708]
experiment: EXISTENCE:mutant phenotype:GO:0006486 protein glycosylation [PMID:8842708]
experiment: EXISTENCE:mutant phenotype:GO:0006490 oligosaccharide-lipid intermediate biosynthetic process [PMID:8842708]
note: Dolichol-P-Man dependent alpha(1-3) mannosyltransferase; involved in synthesis of dolichol-linked oligosaccharide donor for N-linked glycosylation of proteins; G353A missense mutation in human ortholog ALG3 implicated in carbohydrate deficient glycoprotein syndrome type IV, which is characterized by microcephaly, severe epilepsy, minimal psychomotor development, partial deficiency of sialic acids in serum glycoproteins; wild-type human ALG3 can complement yeast alg3 mutant
codon start: 1
product: dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase
translation: MEGEQSPQGEKSLQRKQFVRPPLDLWQDLKDGVRYVIFDCRANLIVMPLLILFESMLCKIIIKKVAYTEIDYKAYMEQIEMIQLDGMLDYSQVSGGTGPLVYPAGHVLIYKMMYWLTEGMDHVERGQVFFRYLYLLTLALQMACYYLLHLPPWCVVLACLSKRLHSIYVLRLFNDCFTTLFMVVTVLGAIVASRCHQRPKLKKSLALVISATYSMAVSIKMNALLYFPAMMISLFILNDANVILTLLDLVAMIAWQVAVAVPFLRSFPQQYLHCAFNFGRKFMYQWSINWQMMDEEAFNDKRFHLALLISHLIALTTLFVTRYPRILPDLWSSLCHPLRKNAVLNANPAKTIPFVLIASNFIGVLFSRSLHYQFLSWYHWTLPILIFWSGMPFFVGPIWYVLHEWCWNSYPPNSQASTLLLALNTVLLLLLALTQLSGSVALAKSHLRTTSSMEKKLN
SIO_010081: YBL082C
subclass of: SO_0000673
so part of: YBL082C
location: complement(69751..71127)
location: region:69751-71127:-1
so has part: feature:69751-71127:-1:exon

NP_009471.1
type: Protein
SIO_000068: ncbiprotein

S000000178
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:69751-71127:-1:exon

YBL081W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBL081W
so part of: sequence
location: <71866..>72972
location: region:71866-72972:1
so has part: feature:71866-72972:1:exon
subclass of: SO_0000010

852197
type: Gene
SIO_000068: ncbigene

position:71866:1
position: 71866
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:72972:1
position: 72972
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:71866-72972:1:exon

YBL081W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBL081W
product: uncharacterized protein
transcript id: NM_001178321.1
SIO_010081: YBL081W
subclass of: SO_0000673
so part of: YBL081W
location: <71866..>72972
location: region:71866-72972:1
so has part: feature:71866-72972:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:71866-72972:1:exon

YBL081W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBL081W
note: Non-essential hypothetical protein; null mutation results in a decrease in plasma membrane electron transport
codon start: 1
product: uncharacterized protein
translation: MPGQIISIPFLSQNEDMDKYLLEYRSLKLLHQSSNSFQSHNAPSHQSNYHPHYNHMKYNNTGSYYYYNNNNNSSVNPHNQAGLQSINRSIPSAPYGAYNQNRANDVPYMNTQKKHHRFSANNNLNQQKYKQYPQYTSNPMVTAHLKQTYPQLYYNSNVNAHNNNNNSNNNNNNNNNSNNNNNLYNQTQFSTRYFNSNSSPSLTSSTSNSSSPYNQSTFEYILPSTSAASTNLSSSSSNNSMHTNPTTATSTSADLINDLPVGPTSSSLISDLHSPPTVSFLPASQTLLMSSTTSSSIGTNINPPQHSPSPSQREDFSTAPVNMSSSASLLMNDSSLGWGSNHMNVSSSSQPASSRPFGIWNTDMSVWS
SIO_010081: YBL081W
subclass of: SO_0000673
so part of: YBL081W
location: 71866..72972
location: region:71866-72972:1
so has part: feature:71866-72972:1:exon

NP_009472.1
type: Protein
SIO_000068: ncbiprotein

S000000177
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:71866-72972:1:exon

YBL080C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PET112
locus tag: YBL080C
so part of: sequence
location: complement(<73070..>74695)
location: region:73070-74695:-1
so has part: feature:73070-74695:-1:exon
subclass of: SO_0000010

852198
type: Gene
SIO_000068: ncbigene

position:73070:-1
position: 73070
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:74695:-1
position: 74695
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:73070-74695:-1:exon

YBL080C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PET112
locus tag: YBL080C
product: glutamyl-tRNA(Gln) amidotransferase subunit PET112
transcript id: NM_001178320.2
SIO_010081: YBL080C
subclass of: SO_0000673
so part of: YBL080C
location: complement(<73070..>74695)
location: region:73070-74695:-1
so has part: feature:73070-74695:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:73070-74695:-1:exon

YBL080C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PET112
locus tag: YBL080C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:19417106|PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex [PMID:19417106]
experiment: EXISTENCE:direct assay:GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity [PMID:19417106]
experiment: EXISTENCE:direct assay:GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation [PMID:19417106]
experiment: EXISTENCE:mutant phenotype:GO:0032543 mitochondrial translation [PMID:8082172]
note: Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex; involved in the formation of Q-tRNAQ; mutation is functionally complemented by the bacterial GatB ortholog
codon start: 1
product: glutamyl-tRNA(Gln) amidotransferase subunit PET112
translation: MLRLARFYSLARTKAIHSHGAPFRPEYALKCGLEIHTQLNTKNKLFSQSTNSATSLVDAPNHHTSYYDIALPGTQPVLNLEAILFAMKLSLALGSQVNSISQFDRKHYFYGDQPQGYQLTQHYRPFARGGKINLSKELDDIDESAKEIGILQLQIEQDTGKSHYTETDKDVITLVDLNRSNVPLIELVTKPDFSDIKQVRAFIKKYQNLVRHLHISSGDLETGAMRVDVNLSINEYARVELKNLPNTSSIINAIKYEYQRQVELISVGDTSSLMEPETRGWTGSSTVKLRSKETTIDYRYMPDPELPYINLAPDVISGVRGLMPQLPDDIMRILMKKPYQLSLKDAKILTYNSNQNDMYNHEALRSYYLDTFREFSKLAGERSNAKLPTNWIIHEFLGDLNKLQIPLAKAKEILPPPVFAQFLKLLHEEVISATSGKMLLFHILENFEQSNCQDLSIPDFSKLIEKFELHAINQVDPQELMDLCNDVIAQHTDDTFIRNLVTGKKKSSLKFLIGQGMRRSQGRIKANEFEKKFKEILNIQW
SIO_010081: YBL080C
subclass of: SO_0000673
so part of: YBL080C
location: complement(73070..74695)
location: region:73070-74695:-1
so has part: feature:73070-74695:-1:exon

NP_009473.2
type: Protein
SIO_000068: ncbiprotein

S000000176
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:73070-74695:-1:exon

YBL079W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: NLE3
gene: NUP170
locus tag: YBL079W
gene synonym: NLE3
so part of: sequence
location: <75259..>79767
location: region:75259-79767:1
so has part: feature:75259-79767:1:exon
subclass of: SO_0000010

852199
type: Gene
SIO_000068: ncbigene

position:75259:1
position: 75259
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:79767:1
position: 79767
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:75259-79767:1:exon

YBL079W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: NLE3
gene: NUP170
locus tag: YBL079W
gene synonym: NLE3
product: Nup170p
transcript id: NM_001178319.1
SIO_010081: YBL079W
subclass of: SO_0000673
so part of: YBL079W
location: <75259..>79767
location: region:75259-79767:1
so has part: feature:75259-79767:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:75259-79767:1:exon

YBL079W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: NLE3
gene: NUP170
locus tag: YBL079W
gene synonym: NLE3
experiment: EXISTENCE:curator inference:GO:0006913 nucleocytoplasmic transport [PMID:10684247]
experiment: EXISTENCE:direct assay:GO:0005643 nuclear pore [PMID:10684247]
experiment: EXISTENCE:direct assay:GO:0044611 nuclear pore inner ring [PMID:18046406]
experiment: EXISTENCE:direct assay:GO:0044877 protein-containing complex binding [PMID:23452847]
experiment: EXISTENCE:direct assay:GO:1990841 promoter-specific chromatin binding [PMID:23452847]
experiment: EXISTENCE:genetic interaction:GO:0017056 structural constituent of nuclear pore [PMID:19414608|PMID:20498018]
experiment: EXISTENCE:genetic interaction:GO:0051292 nuclear pore complex assembly [PMID:20498018|PMID:19414608]
experiment: EXISTENCE:mutant phenotype:GO:0003682 chromatin binding [PMID:23452847]
experiment: EXISTENCE:mutant phenotype:GO:0007059 chromosome segregation [PMID:11290711]
experiment: EXISTENCE:mutant phenotype:GO:0017056 structural constituent of nuclear pore [PMID:12509452|PMID:19414606|PMID:17418788]
experiment: EXISTENCE:mutant phenotype:GO:0031507 heterochromatin formation [PMID:23452847]
experiment: EXISTENCE:mutant phenotype:GO:0034398 telomere tethering at nuclear periphery [PMID:23452847]
experiment: EXISTENCE:mutant phenotype:GO:0036228 protein localization to nuclear inner membrane [PMID:16929305|PMID:21659568]
note: Subunit of inner ring of nuclear pore complex (NPC); contributes to NPC assembly and nucleocytoplasmic transport; interacts with genomic regions that contain ribosomal protein and subtelomeric genes, where it functions in nucleosome positioning and as a repressor of transcription; both Nup170p and Nup157p are similar to human Nup155p; NUP170 has a paralog, NUP157, that arose from the whole genome duplication
codon start: 1
product: Nup170p
translation: MFQSFFHNNGPAAAGETFSDSRSYPLTNHQEVPRNGLNELASSATKAQQQPTHILNSYPITGSNPLMRASAMGATSGSINPNMSNMNEHIRVSGMGTSKPLDLAGKYIDHLQHKDSNTPVLDERSYYNSGVDYNFSREKNGLGAFTPFEKQDVFNIPDEILHEFSTSQTKTDMGIFPELNRCWITIDNKLILWNINNDNEYQVVDDMKHTIQKVALVRPKPNTFVPAVKHLLLISTTMELFMFAISLDKATNELSVFNTHLSVPVQGIDVIDIVSHERSGRIFFAGQASGLNIWELHYSGSDDWFNSKCSKVCLTKSALLSLLPTNMLSQIPGVDFIQALFEDNSNGNGGFSQETITQLTIDQQRGIIYSLSSKSTIRAYVITEKSLEGPMSIEPAYISRIIGTTTARAAPILGPKYLKIVKISSVAPEENNNLFLVALTVGGVRLYFNGSMGRFNIEALRLESIKFPPSSVTPEVIQQELLHQQQEQAKRSFPFFSNLMSSEPVLLKFQKKSSVLLETTKASTIISPGIFFSAVIKSSQQTHQQEKKENSSVTGTTATAGSKTVKQQPVTLQHKLFVSVPDYGILKTHGKYVENATFLETAGPVQQIIPLSGLFNATTKPQGFANEFATQYTSETLRVAVLTSTSIEIYKYRTPDEIFEDLIDNPLPFVLNYGAAEACSTALFVTCKSNKSEKLRSNALTFLTMGIPGVVDIKPVYNRYSVSTVSSLLSKPTLSTATTNLQQSITGFSKPSPANKEDFDLDDVILSPRFYGIALLITRLLRDIWGRHVFMTFTDNRVTSHAFISSSDPITPSINNLKSDEISQNRNIISKVSISKDCIEYYLSSINILNEFFITYGDSISQISAPYVLANNSNGRVIDKTEEVANQAESIAINAMIKMVQSIKEGLSFLNVLYEESEVEGFDNQYLGFKDIISFVSLDVQKDLVKLDFKDLFAPNDKTKSLIREILLSIINRNITKGASIEYTATALQERCGSFCSASDILGFRAIEHLRRAKEIGLRNYDSLNYHLKNATALLEQIVDDLSIEKLKEAVSMMLSVNYYPKSIEFLLNIANSMDKGKLACQYVANGFLENDDRKQYYDKRILVYDLVFDTLIKVDELAEKKQSSKTQNQISISNDDEVKLRQKSYEAALKYNDRLFHYHMYDWLVSQNREEKLLDIETPFILPYLMEKAGSSLKISNILWVYYSRRSKFFESAEILYRLATSNFDITLFERIEFLSRANGFCNSVSPLSQKQRIVQLASRIQDACEVAGIQGDILSLVYTDARIDSAIKDELIKTLDGKILSTSELFNDFAVPLSYHEIALFIFKIADFRDHEVIMAKWDELFQSLRMEFNNTGKKEDSMNFINLLSNVLIKIGKNVQDSEFIFPIFELFPIVCNFFYETLPKEHIVSGSIVSIFITAGVSFNKMYYILKELIETSDSDNSVFNKEMTWLIHEWYKSDRKFRDIISYNDIIHLKEYKIDNDPIEKYVKNSGNNLGICFYKE
SIO_010081: YBL079W
subclass of: SO_0000673
so part of: YBL079W
location: 75259..79767
location: region:75259-79767:1
so has part: feature:75259-79767:1:exon

NP_009474.1
type: Protein
SIO_000068: ncbiprotein

S000000175
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:75259-79767:1:exon

YBL078C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: APG8
alternative label: AUT7
alternative label: CVT5
gene: ATG8
locus tag: YBL078C
gene synonym: APG8; AUT7; CVT5
so part of: sequence
location: complement(<80378..>80731)
location: region:80378-80731:-1
so has part: feature:80378-80731:-1:exon
subclass of: SO_0000010

852200
type: Gene
SIO_000068: ncbigene

position:80378:-1
position: 80378
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:80731:-1
position: 80731
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:80378-80731:-1:exon

YBL078C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: APG8
alternative label: AUT7
alternative label: CVT5
gene: ATG8
locus tag: YBL078C
gene synonym: APG8; AUT7; CVT5
product: ubiquitin-like protein ATG8
transcript id: NM_001178318.1
SIO_010081: YBL078C
subclass of: SO_0000673
so part of: YBL078C
location: complement(<80378..>80731)
location: region:80378-80731:-1
so has part: feature:80378-80731:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:80378-80731:-1:exon

YBL078C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: APG8
alternative label: AUT7
alternative label: CVT5
gene: ATG8
locus tag: YBL078C
gene synonym: APG8; AUT7; CVT5
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:10837468]
experiment: EXISTENCE:direct assay:GO:0000407 phagophore assembly site [PMID:11689437|PMID:15659643|PMID:16680092|PMID:23129774|P MID:19398890]
experiment: EXISTENCE:direct assay:GO:0005776 autophagosome [PMID:10525546|PMID:16079147]
experiment: EXISTENCE:direct assay:GO:0005811 lipid droplet [PMID:28003432]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0061025 membrane fusion [PMID:17632063]
experiment: EXISTENCE:direct assay:GO:0120095 vacuole-isolation membrane contact site [PMID:23549786]
experiment: EXISTENCE:genetic interaction:GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport [PMID:10837468]
experiment: EXISTENCE:mutant phenotype:GO:0000422 autophagy of mitochondrion [PMID:19793921]
experiment: EXISTENCE:mutant phenotype:GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport [PMID:10837468]
experiment: EXISTENCE:mutant phenotype:GO:0008429 phosphatidylethanolamine binding [PMID:19398890]
experiment: EXISTENCE:mutant phenotype:GO:0016241 regulation of macroautophagy [PMID:19398890]
experiment: EXISTENCE:mutant phenotype:GO:0031386 protein tag [PMID:22652539]
experiment: EXISTENCE:mutant phenotype:GO:0031503 protein-containing complex localization [PMID:22885598]
experiment: EXISTENCE:mutant phenotype:GO:0032258 cytoplasm to vacuole transport by the Cvt pathway [PMID:9649430|PMID:19398890]
experiment: EXISTENCE:mutant phenotype:GO:0034497 protein localization to phagophore assembly site [PMID:25680528]
experiment: EXISTENCE:mutant phenotype:GO:0034727 piecemeal microautophagy of the nucleus [PMID:18701704]
experiment: EXISTENCE:mutant phenotype:GO:0044805 late nucleophagy [PMID:22768199]
experiment: EXISTENCE:mutant phenotype:GO:0061025 membrane fusion [PMID:17632063]
experiment: EXISTENCE:mutant phenotype:GO:0061709 reticulophagy [PMID:26181331]
experiment: EXISTENCE:mutant phenotype:GO:0071211 protein targeting to vacuole involved in autophagy [PMID:22885598]
experiment: EXISTENCE:mutant phenotype:GO:0140042 lipid droplet formation [PMID:28003432]
experiment: EXISTENCE:mutant phenotype:GO:1905153 regulation of membrane invagination [PMID:31616012]
experiment: EXISTENCE:physical interaction:GO:0000329 fungal-type vacuole membrane [PMID:10837468]
experiment: EXISTENCE:physical interaction:GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport [PMID:10837468]
note: Ubiquitin-like protein conjugated to phosphatidylethanolamine (PE); role in membrane fusion and phagophore expansion during autophagosome formation; deconjugation is also required for biogenesis; targets Atg1p to autophagosomes; binds to the Atg1p-Atg13p complex, triggers its vacuolar degradation; role in vacuolar membrane protein turnover during early stationary phase; component of autophagosomes and Cvt vesicles; targeted to vacuole via AP-3 pathway
codon start: 1
product: ubiquitin-like protein ATG8
translation: MKSTFKSEYPFEKRKAESERIADRFKNRIPVICEKAEKSDIPEIDKRKYLVPADLTVGQFVYVIRKRIMLPPEKAIFIFVNDTLPPTAALMSAIYQEHKDKDGFLYVTYSGENTFGR
SIO_010081: YBL078C
subclass of: SO_0000673
so part of: YBL078C
location: complement(80378..80731)
location: region:80378-80731:-1
so has part: feature:80378-80731:-1:exon

NP_009475.1
type: Protein
SIO_000068: ncbiprotein

S000000174
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:80378-80731:-1:exon

YBL076C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ILS1
locus tag: YBL076C
so part of: sequence
location: complement(<81043..>84261)
location: region:81043-84261:-1
so has part: feature:81043-84261:-1:exon
subclass of: SO_0000010

852202
type: Gene
SIO_000068: ncbigene

position:81043:-1
position: 81043
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:84261:-1
position: 84261
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:81043-84261:-1:exon

YBL076C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ILS1
locus tag: YBL076C
product: isoleucine--tRNA ligase ILS1
transcript id: NM_001178316.1
SIO_010081: YBL076C
subclass of: SO_0000673
so part of: YBL076C
location: complement(<81043..>84261)
location: region:81043-84261:-1
so has part: feature:81043-84261:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:81043-84261:-1:exon

YBL076C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ILS1
locus tag: YBL076C
EC number: 6.1.1.5
experiment: EXISTENCE:direct assay:GO:0004822 isoleucine-tRNA ligase activity [PMID:7619074|PMID:782885]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:7619074]
experiment: EXISTENCE:direct assay:GO:0006428 isoleucyl-tRNA aminoacylation [PMID:782885]
note: Cytoplasmic isoleucine-tRNA synthetase; target of the G1-specific inhibitor reveromycin A
codon start: 1
product: isoleucine--tRNA ligase ILS1
translation: MSESNAHFSFPKEEEKVLSLWDEIDAFHTSLELTKDKPEFSFFDGPPFATGTPHYGHILASTIKDIVPRYATMTGHHVERRFGWDTHGVPIEHIIDKKLGITGKDDVFKYGLENYNNECRSIVMTYASDWRKTIGRLGRWIDFDNDYKTMYPSFMESTWWAFKQLHEKGQVYRGFKVMPYSTGLTTPLSNFEAQQNYKDVNDPAVTIGFNVIGQEKTQLVAWTTTPWTLPSNLSLCVNADFEYVKIYDETRDRYFILLESLIKTLYKKPKNEKYKIVEKIKGSDLVGLKYEPLFPYFAEQFHETAFRVISDDYVTSDSGTGIVHNAPAFGEEDNAACLKNGVISEDSVLPNAIDDLGRFTKDVPDFEGVYVKDADKLIIKYLTNTGNLLLASQIRHSYPFCWRSDTPLLYRSVPAWFVRVKNIVPQMLDSVMKSHWVPNTIKEKRFANWIANARDWNVSRNRYWGTPIPLWVSDDFEEVVCVGSIKELEELTGVRNITDLHRDVIDKLTIPSKQGKGDLKRIEEVFDCWFESGSMPYASQHYPFENTEKFDERVPANFISEGLDQTRGWFYTLAVLGTHLFGSVPYKNVIVSGIVLAADGRKMSKSLKNYPDPSIVLNKYGADALRLYLINSPVLKAESLKFKEEGVKEVVSKVLLPWWNSFKFLDGQIALLKKMSNIDFQYDDSVKSDNVMDRWILASMQSLVQFIHEEMGQYKLYTVVPKLLNFIDELTNWYIRFNRRRLKGENGVEDCLKALNSLFDALFTFVRAMAPFTPFLSESIYLRLKEYIPEAVLAKYGKDGRSVHFLSYPVVKKEYFDEAIETAVSRMQSVIDLGRNIREKKTISLKTPLKTLVILHSDESYLKDVEALKNYIIEELNVRDVVITSDEAKYGVEYKAVADWPVLGKKLKKDAKKVKDALPSVTSEQVREYLESGKLEVAGIELVKGDLNAIRGLPESAVQAGQETRTDQDVLIIMDTNIYSELKSEGLARELVNRIQKLRKKCGLEATDDVLVEYELVKDTIDFEAIVKEHFDMLSKTCRSDIAKYDGSKTDPIGDEEQSINDTIFKLKVFKL
SIO_010081: YBL076C
subclass of: SO_0000673
so part of: YBL076C
location: complement(81043..84261)
location: region:81043-84261:-1
so has part: feature:81043-84261:-1:exon

NP_009477.1
type: Protein
SIO_000068: ncbiprotein

S000000172
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:81043-84261:-1:exon

YBL075C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YG106
gene: SSA3
locus tag: YBL075C
gene synonym: YG106
so part of: sequence
location: complement(<84499..>86448)
location: region:84499-86448:-1
so has part: feature:84499-86448:-1:exon
subclass of: SO_0000010

852203
type: Gene
SIO_000068: ncbigene

position:84499:-1
position: 84499
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:86448:-1
position: 86448
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:84499-86448:-1:exon

YBL075C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YG106
gene: SSA3
locus tag: YBL075C
gene synonym: YG106
product: Hsp70 family ATPase SSA3
transcript id: NM_001178315.1
SIO_010081: YBL075C
subclass of: SO_0000673
so part of: YBL075C
location: complement(<84499..>86448)
location: region:84499-86448:-1
so has part: feature:84499-86448:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:84499-86448:-1:exon

YBL075C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YG106
gene: SSA3
locus tag: YBL075C
gene synonym: YG106
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:10745074]
experiment: EXISTENCE:genetic interaction:GO:0006457 protein folding [PMID:9789005]
experiment: EXISTENCE:genetic interaction:GO:0016887 ATP hydrolysis activity [PMID:3302682]
experiment: EXISTENCE:genetic interaction:GO:0051082 unfolded protein binding [PMID:9789005]
experiment: EXISTENCE:mutant phenotype:GO:0006515 protein quality control for misfolded or incompletely synthesized proteins [PMID:24855027]
experiment: EXISTENCE:mutant phenotype:GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation [PMID:8754838]
note: ATPase involved in protein folding and the response to stress; plays a role in SRP-dependent cotranslational protein-membrane targeting and translocation; member of the heat shock protein 70 (HSP70) family; localized to the cytoplasm; SSA3 has a paralog, SSA4, that arose from the whole genome duplication
codon start: 1
product: Hsp70 family ATPase SSA3
translation: MSRAVGIDLGTTYSCVAHFSNDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQAAINPHNTVFDAKRLIGRKFDDPEVTTDAKHFPFKVISRDGKPVVQVEYKGETKTFTPEEISSMVLSKMKETAENYLGTTVNDAVVTVPAYFNDSQRQATKDAGTIAGMNVLRIINEPTAAAIAYGLDKKGRAEHNVLIFDLGGGTFDVSLLSIDEGVFEVKATAGDTHLGGEDFDNRLVNHLATEFKRKTKKDISNNQRSLRRLRTAAERAKRALSSSSQTSIEIDSLFEGMDFYTSLTRARFEELCADLFRSTLEPVEKVLKDSKLDKSQIDEIVLVGGSTRIPKIQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGDQSTKTQDLLLLDVAPLSLGIETAGGIMTKLIPRNSTIPTKKSETFSTYADNQPGVLIQVFEGERTRTKDNNLLGKFELSGIPPAPRGVPQIDVTFDIDANGILNVSALEKGTGKSNKITITNDKGRLSKDDIDRMVSEAEKYRADDEREAERVQAKNQLESYAFTLKNTINEASFKEKVGEDDAKRLETASQETIDWLDASQAASTDEYKDRQKELEGIANPIMTKFYGAGAGAGPGAGESGGFPGSMPNSGATGGGEDTGPTVEEVD
SIO_010081: YBL075C
subclass of: SO_0000673
so part of: YBL075C
location: complement(84499..86448)
location: region:84499-86448:-1
so has part: feature:84499-86448:-1:exon

NP_009478.1
type: Protein
SIO_000068: ncbiprotein

S000000171
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:84499-86448:-1:exon

YBL074C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: AAR2
locus tag: YBL074C
so part of: sequence
location: complement(<86722..>87789)
location: region:86722-87789:-1
so has part: feature:86722-87789:-1:exon
subclass of: SO_0000010

852205
type: Gene
SIO_000068: ncbigene

position:86722:-1
position: 86722
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:87789:-1
position: 87789
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:86722-87789:-1:exon

YBL074C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: AAR2
locus tag: YBL074C
product: U5 snRNP complex subunit AAR2
transcript id: NM_001178314.1
SIO_010081: YBL074C
subclass of: SO_0000673
so part of: YBL074C
location: complement(<86722..>87789)
location: region:86722-87789:-1
so has part: feature:86722-87789:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:86722-87789:-1:exon

YBL074C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: AAR2
locus tag: YBL074C
experiment: EXISTENCE:direct assay:GO:0005682 U5 snRNP [PMID:11720285]
experiment: EXISTENCE:mutant phenotype:GO:0000244 spliceosomal tri-snRNP complex assembly [PMID:11720285]
note: Component of the U5 snRNP complex; required for splicing of U3 precursors; originally described as a splicing factor specifically required for splicing pre-mRNA of the MATa1 cistron
codon start: 1
product: U5 snRNP complex subunit AAR2
translation: MNTVPFTSAPIEVTIGIDQYSFNVKENQPFHGIKDIPIGHVHVIHFQHADNSSMRYGYWFDCRMGNFYIQYDPKDGLYKMMEERDGAKFENIVHNFKERQMMVSYPKIDEDDTWYNLTEFVQMDKIRKIVRKDENQFSYVDSSMTTVQENELLKSSLQKAGSKMEAKNEDDPAHSLNYTVINFKSREAIRPGHEMEDFLDKSYYLNTVMLQGIFKNSSNYFGELQFAFLNAMFFGNYGSSLQWHAMIELICSSATVPKHMLDKLDEILYYQIKTLPEQYSDILLNERVWNICLYSSFQKNSLHNTEKIMENKYPELLGKDNEDDALIYGISDEERDDEDDEHNPTIVGGLYYQRP
SIO_010081: YBL074C
subclass of: SO_0000673
so part of: YBL074C
location: complement(86722..87789)
location: region:86722-87789:-1
so has part: feature:86722-87789:-1:exon

NP_009479.1
type: Protein
SIO_000068: ncbiprotein

S000000170
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:86722-87789:-1:exon

YNCB0003W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SNR56
locus tag: YNCB0003W
so part of: sequence
location: 88190..88277
location: region:88190-88277:1
so has part: feature:88190-88277:1:exon
subclass of: SO_0000578

9164868
type: Gene
SIO_000068: ncbigene

position:88190:1
position: 88190
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:88277:1
position: 88277
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:88190-88277:1:exon

YNCB0003W
type: Non Coding RNA
subclass of: SO_0000655
RO_0002162: 559292
nc RNA class: snoRNA
gene: SNR56
locus tag: YNCB0003W
product: SNR56
experiment: EXISTENCE:curator inference:GO:0005730 nucleolus [PMID:10024243]
experiment: EXISTENCE:curator inference:GO:0031428 box C/D RNP complex [PMID:10024243]
experiment: EXISTENCE:mutant phenotype:GO:0030562 rRNA 2'-O-ribose methylation guide activity [PMID:10024243]
experiment: EXISTENCE:mutant phenotype:GO:0031167 rRNA methylation [PMID:10024243]
note: C/D box small nucleolar RNA (snoRNA); guides 2'-O-methylation of small subunit (SSU) rRNA at position G1428
transcript id: NR_132151.1
SIO_010081: YNCB0003W
subclass of: SO_0000673
so part of: YNCB0003W
location: 88190..88277
location: region:88190-88277:1
so has part: feature:88190-88277:1:exon

S000006447
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:88190-88277:1:exon

YBL072C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RPS8A
locus tag: YBL072C
so part of: sequence
location: complement(<88523..>89125)
location: region:88523-89125:-1
so has part: feature:88523-89125:-1:exon
subclass of: SO_0000010

852206
type: Gene
SIO_000068: ncbigene

position:88523:-1
position: 88523
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:89125:-1
position: 89125
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:88523-89125:-1:exon

YBL072C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RPS8A
locus tag: YBL072C
product: ribosomal 40S subunit protein S8A
transcript id: NM_001178312.1
SIO_010081: YBL072C
subclass of: SO_0000673
so part of: YBL072C
location: complement(<88523..>89125)
location: region:88523-89125:-1
so has part: feature:88523-89125:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:88523-89125:-1:exon

YBL072C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RPS8A
locus tag: YBL072C
experiment: EXISTENCE:curator inference:GO:0002181 cytoplasmic translation [PMID:18782943]
experiment: EXISTENCE:direct assay:GO:0003735 structural constituent of ribosome [PMID:18782943]
experiment: EXISTENCE:direct assay:GO:0022627 cytosolic small ribosomal subunit [PMID:18782943]
experiment: EXISTENCE:direct assay:GO:0030686 90S preribosome [PMID:12150911]
experiment: EXISTENCE:genetic interaction:GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:16246728]
note: Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S8, no bacterial homolog; RPS8A has a paralog, RPS8B, that arose from the whole genome duplication
codon start: 1
product: ribosomal 40S subunit protein S8A
translation: MGISRDSRHKRSATGAKRAQFRKKRKFELGRQPANTKIGAKRIHSVRTRGGNKKYRALRIETGNFSWASEGISKKTRIAGVVYHPSNNELVRTNTLTKAAIVQIDATPFRQWFEAHYGQTLGKKKNVKEEETVAKSKNAERKWAARAASAKIESSVESQFSAGRLYACISSRPGQSGRCDGYILEGEELAFYLRRLTAKK
SIO_010081: YBL072C
subclass of: SO_0000673
so part of: YBL072C
location: complement(88523..89125)
location: region:88523-89125:-1
so has part: feature:88523-89125:-1:exon

NP_009481.1
type: Protein
SIO_000068: ncbiprotein

S000000168
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:88523-89125:-1:exon

YBL071C-B
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBL071C-B
so part of: sequence
location: complement(<89458..>89556)
location: region:89458-89556:-1
so has part: feature:89458-89556:-1:exon
subclass of: SO_0000010

1466440
type: Gene
SIO_000068: ncbigene

position:89458:-1
position: 89458
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:89556:-1
position: 89556
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:89458-89556:-1:exon

YBL071C-B
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBL071C-B
product: uncharacterized protein
transcript id: NM_001184584.1
SIO_010081: YBL071C-B
subclass of: SO_0000673
so part of: YBL071C-B
location: complement(<89458..>89556)
location: region:89458-89556:-1
so has part: feature:89458-89556:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:89458-89556:-1:exon

YBL071C-B
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBL071C-B
note: hypothetical protein; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
codon start: 1
product: uncharacterized protein
translation: MELFHIRYLQAYLKVIGNYTCHLLFGTHKKTL
SIO_010081: YBL071C-B
subclass of: SO_0000673
so part of: YBL071C-B
location: complement(89458..89556)
location: region:89458-89556:-1
so has part: feature:89458-89556:-1:exon

NP_878044.1
type: Protein
SIO_000068: ncbiprotein

S000028597
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:89458-89556:-1:exon

YBL071W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: DPH3
gene: KTI11
locus tag: YBL071W-A
gene synonym: DPH3
so part of: sequence
location: <89978..>90226
location: region:89978-90226:1
so has part: feature:89978-90226:1:exon
subclass of: SO_0000010

852207
type: Gene
SIO_000068: ncbigene

position:89978:1
position: 89978
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:90226:1
position: 90226
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:89978-90226:1:exon

YBL071W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: DPH3
gene: KTI11
locus tag: YBL071W-A
gene synonym: DPH3
product: Kti11p
transcript id: NM_001184454.1
SIO_010081: YBL071W-A
subclass of: SO_0000673
so part of: YBL071W-A
location: <89978..>90226
location: region:89978-90226:1
so has part: feature:89978-90226:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:89978-90226:1:exon

YBL071W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: DPH3
gene: KTI11
locus tag: YBL071W-A
gene synonym: DPH3
experiment: EXISTENCE:direct assay:GO:0005506 iron ion binding [PMID:18021800|PMID:34154323]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:18627462|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:18627462|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:34154323]
experiment: EXISTENCE:direct assay:GO:0008270 zinc ion binding [PMID:18021800]
experiment: EXISTENCE:direct assay:GO:0016730 oxidoreductase activity, acting on iron-sulfur proteins as donors [PMID:18021800]
experiment: EXISTENCE:direct assay:GO:0017183 peptidyl-diphthamide biosynthetic process from peptidyl-histidine [PMID:34154323]
experiment: EXISTENCE:direct assay:GO:0045182 translation regulator activity [PMID:34154323]
experiment: EXISTENCE:mutant phenotype:GO:0002098 tRNA wobble uridine modification [PMID:18755837]
experiment: EXISTENCE:mutant phenotype:GO:0017183 peptidyl-diphthamide biosynthetic process from peptidyl-histidine [PMID:15485916]
note: Zn-ribbon protein that co-purifies with Dph1 and Dph2; forms a complex required for synthesis of diphthamide on translation factor eEF2 and with Elongator subunits Iki3p, Elp2p, and Elp3p; involved in modification of wobble nucleosides in tRNAs; forms a stable heterodimer with Ats1p
codon start: 1
product: Kti11p
translation: MSTYDEIEIEDMTFEPENQMFTYPCPCGDRFQIYLDDMFEGEKVAVCPSCSLMIDVVFDKEDLAEYYEEAGIHPPEPIAAAA
SIO_010081: YBL071W-A
subclass of: SO_0000673
so part of: YBL071W-A
location: 89978..90226
location: region:89978-90226:1
so has part: feature:89978-90226:1:exon

NP_660100.1
type: Protein
SIO_000068: ncbiprotein

S000007587
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:89978-90226:1:exon

YBL071C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBL071C
so part of: sequence
location: complement(<90223..>90531)
location: region:90223-90531:-1
so has part: feature:90223-90531:-1:exon
subclass of: SO_0000010

852208
type: Gene
SIO_000068: ncbigene

position:90223:-1
position: 90223
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:90531:-1
position: 90531
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:90223-90531:-1:exon

YBL071C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBL071C
product: uncharacterized protein
transcript id: NM_001346794.1
SIO_010081: YBL071C
subclass of: SO_0000673
so part of: YBL071C
location: complement(<90223..>90531)
location: region:90223-90531:-1
so has part: feature:90223-90531:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:90223-90531:-1:exon

YBL071C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBL071C
note: hypothetical protein; conserved among S. cerevisiae strains; YBL071C is not an essential gene
codon start: 1
product: uncharacterized protein
translation: MILLKSEHGGKRKEMRQDDLMGPNHFSLRIMYKIIIYTYPVSLYAVKELNLSKTFSISALGILNSNSNRSPAKKQTFFSACVAKSYSSFFISICILDLASHL
SIO_010081: YBL071C
subclass of: SO_0000673
so part of: YBL071C
location: complement(90223..90531)
location: region:90223-90531:-1
so has part: feature:90223-90531:-1:exon

NP_001333723.1
type: Protein
SIO_000068: ncbiprotein

S000000167
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:90223-90531:-1:exon

YBL069W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: AST1
locus tag: YBL069W
so part of: sequence
location: <90741..>92030
location: region:90741-92030:1
so has part: feature:90741-92030:1:exon
subclass of: SO_0000010

852209
type: Gene
SIO_000068: ncbigene

position:90741:1
position: 90741
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:92030:1
position: 92030
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:90741-92030:1:exon

YBL069W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: AST1
locus tag: YBL069W
product: Ast1p
transcript id: NM_001178309.1
SIO_010081: YBL069W
subclass of: SO_0000673
so part of: YBL069W
location: <90741..>92030
location: region:90741-92030:1
so has part: feature:90741-92030:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:90741-92030:1:exon

YBL069W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: AST1
locus tag: YBL069W
experiment: EXISTENCE:direct assay:GO:0005770 late endosome [PMID:11739806]
experiment: EXISTENCE:direct assay:GO:0005794 Golgi apparatus [PMID:11739806]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:11739806]
experiment: EXISTENCE:direct assay:GO:0045121 membrane raft [PMID:11739806]
experiment: EXISTENCE:genetic interaction:GO:0006612 protein targeting to membrane [PMID:7822420]
experiment: EXISTENCE:mutant phenotype:GO:0032596 protein transport into membrane raft [PMID:11739806]
experiment: EXISTENCE:physical interaction:GO:0032596 protein transport into membrane raft [PMID:11739806]
note: Lipid raft associated protein; interacts with the plasma membrane ATPase Pma1p and has a role in its targeting to the plasma membrane by influencing its incorporation into lipid rafts; sometimes classified in the medium-chain dehydrogenase/reductases (MDRs) superfamily; AST1 has a paralog, AST2, that arose from the whole genome duplication
codon start: 1
product: Ast1p
translation: MAKDILKNQDPKLQAMIVEHSAPAPKEIPMDAPVLKRVARPLRHVKFIPIKSLIFHTKTGPMDFSYEKKIKTPIPKNKIVVRVSNVGLNPVDMKIRNGYTSSIYGEIGLGREYSGVITEVGENLNYAWHVGDEVYGIYYHPHLAVGCLQSSILVDPKVDPILLRPESVSAEEAAGSLFCLATGYNILNKLSKNKYLKQDSNVLINGGTSSVGMFVIQLLKRHYKLQKKLVIVTSANGPQVLQEKFPDLADEMIFIDYLTCRGKSSKPLRKMLEEKKISQYDPVEDKETILNYNEGKFDVVLDFVGGYDILSHSSSLIHGGGAYVTTVGDYVANYKEDIFDSWDNPSANARKMFGSIIWSYNYTHYYFDPNAKTASANNDWIEQCGDFLKNGTVKCVVDKVYDWKDHKEAFSYMATQRAQGKLIMNVEKF
SIO_010081: YBL069W
subclass of: SO_0000673
so part of: YBL069W
location: 90741..92030
location: region:90741-92030:1
so has part: feature:90741-92030:1:exon

NP_009484.2
type: Protein
SIO_000068: ncbiprotein

S000000165
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:90741-92030:1:exon

YBL068W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PRS4
locus tag: YBL068W
so part of: sequence
location: <92414..>93394
location: region:92414-93394:1
so has part: feature:92414-93394:1:exon
subclass of: SO_0000010

852211
type: Gene
SIO_000068: ncbigene

position:92414:1
position: 92414
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:93394:1
position: 93394
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:92414-93394:1:exon

YBL068W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PRS4
locus tag: YBL068W
product: ribose phosphate diphosphokinase subunit PRS4
transcript id: NM_001178308.2
SIO_010081: YBL068W
subclass of: SO_0000673
so part of: YBL068W
location: <92414..>93394
location: region:92414-93394:1
so has part: feature:92414-93394:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:92414-93394:1:exon

YBL068W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PRS4
locus tag: YBL068W
EC number: 2.7.6.1
experiment: EXISTENCE:direct assay:GO:0002189 ribose phosphate diphosphokinase complex [PMID:15280369]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:genetic interaction:GO:0004749 ribose phosphate diphosphokinase activity [PMID:15280369]
experiment: EXISTENCE:genetic interaction:GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process [PMID:15280369]
experiment: EXISTENCE:mutant phenotype:GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process [PMID:10212224]
experiment: EXISTENCE:physical interaction:GO:0031505 fungal-type cell wall organization [PMID:15470112]
note: 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP; which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes; PRS4 has a paralog, PRS2, that arose from the whole genome duplication; a missense mutation in the conserved residue R196 of its human homolog PRPS1 is pathogenic
codon start: 1
product: ribose phosphate diphosphokinase subunit PRS4
translation: MNSESREDMAINSIKLLAGNSHPDLAEQISKKLGIPLSKVGVYQYSNKETSVTIGESLRDEDVYIIQTGIGEQEINDFLMELLILIHACKIASARKITTVIPNFPYARQDKKDKSRAPITAKLVANLLQTAGADHVITMDLHASQIQGFFHIPVDNLYAEPSVLNYIRTKTDFDNAILVSPDAGGAKRVAALADKLDLNFALIHKERQKANEVSKMVLVGDVTNKSCLLVDDMADTCGTLVKACDTLMEHGAKEVIAIVTHGIFSGSAREKLRNSRLSRIVCTNTVPVDLDLPIADQIDISPTFAEAIRRLHNGESVSYLFTHAPV
SIO_010081: YBL068W
subclass of: SO_0000673
so part of: YBL068W
location: 92414..93394
location: region:92414-93394:1
so has part: feature:92414-93394:1:exon

NP_009485.3
type: Protein
SIO_000068: ncbiprotein

S000000164
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:92414-93394:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS203; Autonomously replicating sequence
so part of: sequence
location: 93435..93519
location: region:93435-93519:1
so has part: feature:93435-93519:1:region

S000178041
type: SGD
SIO_000068: sgd

position:93435:1
position: 93435
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:93519:1
position: 93519
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:93435-93519:1:region

YBL067C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: UBP13
locus tag: YBL067C
so part of: sequence
location: complement(<93639..>95882)
location: region:93639-95882:-1
so has part: feature:93639-95882:-1:exon
subclass of: SO_0000010

852212
type: Gene
SIO_000068: ncbigene

position:93639:-1
position: 93639
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:95882:-1
position: 95882
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:93639-95882:-1:exon

YBL067C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: UBP13
locus tag: YBL067C
product: ubiquitin-specific protease UBP13
transcript id: NM_001178307.2
SIO_010081: YBL067C
subclass of: SO_0000673
so part of: YBL067C
location: complement(<93639..>95882)
location: region:93639-95882:-1
so has part: feature:93639-95882:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:93639-95882:-1:exon

YBL067C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: UBP13
locus tag: YBL067C
EC number: 3.4.19.12
experiment: EXISTENCE:direct assay:GO:0004843 cysteine-type deubiquitinase activity [PMID:11076031]
experiment: EXISTENCE:mutant phenotype:GO:0010995 free ubiquitin chain depolymerization [PMID:11076031]
note: Ubiquitin-specific protease that cleaves Ub-protein fusions; UBP13 has a paralog, UBP9, that arose from the whole genome duplication
codon start: 1
product: ubiquitin-specific protease UBP13
translation: MIRRWLTISKSGKKKKAVNDTITEEVEKVDFKPVNHDINDELCYSESSDNPSSSLFVSNLDTKETFLNEDNNLQISSGLDYSSETCNQGSNYSQDGIFYISNAKAINAYGGIITQGPEAPILAMKVSDSMPYGDGSNKVFGYENFGNTCYCNSVLQCLYNLSSLRENILQFPKKSRESDQPRKKEMRGKKPRIFTEASFEKSIAGTNGHLPNPKPQSVDDGKPTPVNSVNSNTAGPSEKKSKFFKSFSAKHVQDNNKKEGSPAILTTGKPSSRPQDAPPLIVETPNEPGAPSRLSFENVTDRPPDVPRKIIVGRVLNYENPSRGSSNSNNLDLKGESNSSLSTPLDKKDTRRSSSSSQISPEHRKKSALIRGPVLNIDHSLNGSDKATLYSSLRDIFECITENTYLTGVVSPSSFVDVLKRENVLFNTTMHQDAHEFFNFLLNELSEYIERENKKIAASDINSDSEPSKSKNFISDLFQGTLTNQIKCLTCDNITSRDEPFLDFPIEVQGDEETDIQEILKSYHQREMLNGSNKFYCDECCGLQEAERLVGLKQLPDTLTLHLKRFKYSEKQNCNIKLFNNIHYPLTLNVCSSINSKVCQKYELAGIVVHMGGGPQHGHYVSLCKHEKFGWLLFDDETVEAVKEETVLEFTGESPNMATAYVLFYKAMYSNAVEKNDRENMAKEQDDNIDNLIKYDDWLRTCNSGQKKKEELPIADDLDTAIDDSFVSNTPIKSSKKKSRMFSFRKS
SIO_010081: YBL067C
subclass of: SO_0000673
so part of: YBL067C
location: complement(93639..95882)
location: region:93639-95882:-1
so has part: feature:93639-95882:-1:exon

NP_009486.3
type: Protein
SIO_000068: ncbiprotein

S000000163
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:93639-95882:-1:exon

YBL066C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SEF1
locus tag: YBL066C
so part of: sequence
location: complement(<96669..>100115)
location: region:96669-100115:-1
so has part: feature:96669-100115:-1:exon
subclass of: SO_0000010

852214
type: Gene
SIO_000068: ncbigene

position:96669:-1
position: 96669
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:100115:-1
position: 100115
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:96669-100115:-1:exon

YBL066C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SEF1
locus tag: YBL066C
product: Sef1p
transcript id: NM_001178306.1
SIO_010081: YBL066C
subclass of: SO_0000673
so part of: YBL066C
location: complement(<96669..>100115)
location: region:96669-100115:-1
so has part: feature:96669-100115:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:96669-100115:-1:exon

YBL066C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SEF1
locus tag: YBL066C
note: Putative transcription factor; has homolog in Kluyveromyces lactis
codon start: 1
product: Sef1p
translation: MVKDNRDSDQDQDFSSAHMKRQPEQQQLQQHQFPSKKQRISHHDDSHQINHRPVTSCTHCRQHKIKCDASQNFPHPCSRCEKIGLHCEINPQFRPKKGSQLQLLRQDVDEIKSKLDTLLANDSVFVHLLQQIPMGNSLLNKLNLHPTPTPGTIIPNPDSSPSSGSPTSSAAQRDSKVSVQTYLSREPQLLQANQGSNTNKFKANNEASSHMTLRASSLAQDSKGLVATEPNKLPPLLNDSALPNNSKESLPPALQMAFYKNNSAGNTPNGPFSPIQKTYSPHTTSTTVTTTTNQPPFAATSHVATNNNADRTKTPVVATTTTMPLLPSPHANVDEFVLGDISISIEKANRLHHIFVTRYLPYFPIMYSNNATELYSQSQLLFWTVMLTACLSDPEPTMYCKLSSLIKQLAIETCWIRTPRSTHISQALLILCIWPLPNQKVLDDCSYRFVGLAKSLSYQLGLHRGEFISEFTRTQTSMPNAEKWRTRTWLGIFFAELCWASILGLPPTSQTDYLLEKALSCGDEESEEDNNDSIDNNNNDKRNKKDEPHVESKYKLPGSFRRLLSLANFQAKLSHIIGSSTSSPDGLLEPKYRAETLSILGKELDLLAKTLNFQSDDTVNIYFLYVKLTVCCFAFLPETPPTDQIPYVTEAYLTATKIVTLLNNLLETHQLIELPIYIRQAATFSALILFKLQLTPLLPDKYFDSARQSVVTIHRLYRNQLTAWATSVENDISRTASMLEKLNFVLIMHPEVFVEEDGIISRMRSHLTGSLFYDLVWCVHEARRREMDPEYNKQALEKAAKKRKFSSNGIYNGTSSTGGITDRKLYPLPLYNHISRDDFETVTKTTPSGTTVTTLVPTKNALKQAEKLAKTNNGDSDGSIMEINGIPLSMLGETGSVKFQSLFANTSNSNDYNNNRTLLDASNDISIPSNSIYPVASVPASNNNPQSTKVDYYSNGPSVIPDLSMKRSVSTPVNHFPASVPGLRNHPVGNLSNNVTLGIDHPIPREHSNLQNVTMNYNNQFSNANAIGRSQSSMSHSRTPIASKSNNMTDLHSVVSDPGSSKSTAYPPLSLFSKSNDINSNKTNQRFSTGTNTVTSSNFQTIDNENNVKTPGNKLTDFFQQQSAGWIEGNSSNDDFFGWFDMNMEQGF
SIO_010081: YBL066C
subclass of: SO_0000673
so part of: YBL066C
location: complement(96669..100115)
location: region:96669-100115:-1
so has part: feature:96669-100115:-1:exon

NP_009487.2
type: Protein
SIO_000068: ncbiprotein

S000000162
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:96669-100115:-1:exon

YBL064C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PRX1
locus tag: YBL064C
so part of: sequence
location: complement(<100371..>101156)
location: region:100371-101156:-1
so has part: feature:100371-101156:-1:exon
subclass of: SO_0000010

852215
type: Gene
SIO_000068: ncbigene

position:100371:-1
position: 100371
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:101156:-1
position: 101156
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:100371-101156:-1:exon

YBL064C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PRX1
locus tag: YBL064C
product: thioredoxin peroxidase PRX1
transcript id: NM_001178304.1
SIO_010081: YBL064C
subclass of: SO_0000673
so part of: YBL064C
location: complement(<100371..>101156)
location: region:100371-101156:-1
so has part: feature:100371-101156:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:100371-101156:-1:exon

YBL064C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PRX1
locus tag: YBL064C
EC number: 1.11.1.25
EC number: 1.11.1.27
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:10681558|PMID:10821871|PMID:14576278|PMID:16823961|P MID:24769239]
experiment: EXISTENCE:direct assay:GO:0008379 thioredoxin peroxidase activity [PMID:10681558|PMID:10821871]
experiment: EXISTENCE:direct assay:GO:0045454 cell redox homeostasis [PMID:10681558]
experiment: EXISTENCE:genetic interaction:GO:0034599 cellular response to oxidative stress [PMID:15051715]
experiment: EXISTENCE:mutant phenotype:GO:0008379 thioredoxin peroxidase activity [PMID:10681558]
experiment: EXISTENCE:mutant phenotype:GO:0045454 cell redox homeostasis [PMID:10681558]
experiment: EXISTENCE:mutant phenotype:GO:0046686 response to cadmium ion [PMID:19332553]
experiment: EXISTENCE:mutant phenotype:GO:1903205 regulation of hydrogen peroxide-induced cell death [PMID:31389622]
note: Mitochondrial peroxiredoxin with thioredoxin peroxidase activity; has a role in reduction of hydroperoxides; reactivation requires Trr2p and glutathione; induced during respiratory growth and oxidative stress; phosphorylated; protein abundance increases in response to DNA replication stress
codon start: 1
product: thioredoxin peroxidase PRX1
translation: MFSRICSAQLKRTAWTLPKQAHLQSQTIKTFATAPILCKQFKQSDQPRLRINSDAPNFDADTTVGKINFYDYLGDSWGVLFSHPADFTPVCTTEVSAFAKLKPEFDKRNVKLIGLSVEDVESHEKWIQDIKEIAKVKNVGFPIIGDTFRNVAFLYDMVDAEGFKNINDGSLKTVRSVFVIDPKKKIRLIFTYPSTVGRNTSEVLRVIDALQLTDKEGVVTPINWQPADDVIIPPSVSNDEAKAKFGQFNEIKPYLRFTKSK
SIO_010081: YBL064C
subclass of: SO_0000673
so part of: YBL064C
location: complement(100371..101156)
location: region:100371-101156:-1
so has part: feature:100371-101156:-1:exon

NP_009489.1
type: Protein
SIO_000068: ncbiprotein

S000000160
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:100371-101156:-1:exon

YBL063W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CIN9
gene: KIP1
locus tag: YBL063W
gene synonym: CIN9
so part of: sequence
location: <101886..>105221
location: region:101886-105221:1
so has part: feature:101886-105221:1:exon
subclass of: SO_0000010

852216
type: Gene
SIO_000068: ncbigene

position:101886:1
position: 101886
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:105221:1
position: 105221
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:101886-105221:1:exon

YBL063W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CIN9
gene: KIP1
locus tag: YBL063W
gene synonym: CIN9
product: Kip1p
transcript id: NM_001178303.1
SIO_010081: YBL063W
subclass of: SO_0000673
so part of: YBL063W
location: <101886..>105221
location: region:101886-105221:1
so has part: feature:101886-105221:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:101886-105221:1:exon

YBL063W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CIN9
gene: KIP1
locus tag: YBL063W
gene synonym: CIN9
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005876 spindle microtubule [PMID:1618910]
experiment: EXISTENCE:genetic interaction:GO:0000070 mitotic sister chromatid segregation [PMID:7860634]
experiment: EXISTENCE:genetic interaction:GO:0000073 initial mitotic spindle pole body separation [PMID:1618897|PMID:1618910]
experiment: EXISTENCE:genetic interaction:GO:0003777 microtubule motor activity [PMID:1618910]
experiment: EXISTENCE:mutant phenotype:GO:0000022 mitotic spindle elongation [PMID:9813090]
experiment: EXISTENCE:mutant phenotype:GO:0007019 microtubule depolymerization [PMID:19041752]
experiment: EXISTENCE:mutant phenotype:GO:0030543 2-micrometer plasmid partitioning [PMID:19364922]
experiment: EXISTENCE:mutant phenotype:GO:0090307 mitotic spindle assembly [PMID:9813090]
note: Kinesin-related motor protein; tracks plus-ends and stabilizes microtubules; required for mitotic spindle assembly, chromosome segregation, and 2 micron plasmid partitioning; functionally redundant with Cin8p for chromosomal but not plasmid functions
codon start: 1
product: Kip1p
translation: MARSSLPNRRTAQFEANKRRTIAHAPSPSLSNGMHTLTPPTCNNGAATSDSNIHVYVRCRSRNKREIEEKSSVVISTLGPQGKEIILSNGSHQSYSSSKKTYQFDQVFGAESDQETVFNATAKNYIKEMLHGYNCTIFAYGQTGTGKTYTMSGDINILGDVQSTDNLLLGEHAGIIPRVLVDLFKELSSLNKEYSVKISFLELYNENLKDLLSDSEDDDPAVNDPKRQIRIFDNNNNNSSIMVKGMQEIFINSAHEGLNLLMQGSLKRKVAATKCNDLSSRSHTVFTITTNIVEQDSKDHGQNKNFVKIGKLNLVDLAGSENINRSGAENKRAQEAGLINKSLLTLGRVINALVDHSNHIPYRESKLTRLLQDSLGGMTKTCIIATISPAKISMEETASTLEYATRAKSIKNTPQVNQSLSKDTCLKDYIQEIEKLRNDLKNSRNKQGIFITQDQLDLYESNSILIDEQNLKIHNLREQIKKFKENYLNQLDINNLLQSEKEKLIAIIQNFNVDFSNFYSEIQKIHHTNLELMNEVIQQRDFSLENSQKQYNTNQNMQLKISQQVLQTLNTLQGSLNNYNSKCSEVIKGVTEELTRNVNTHKAKHDSTLKSLLNITTNLLMNQMNELVRSISTSLEIFQSDSTSHYRKDLNEIYQSHQQFLKNLQNDIKSCLDSIGSSILTSINEISQNCTTNLNSMNVLIENQQSGSSKLIKEQDLEIKKLKNDLINERRISNQFNQQLAEMKRYFQDHVSRTRSEFHDELNKCIDNLKDKQSKLDQDIWQKTASIFNETDIVVNKIHSDSIASLAHNAENTLKTVSQNNESFTNDLISLSRGMNMDISSKLRSLPINEFLNKISQTICETCGDDNTIASNPVLTSIKKFQNIICSDIALTNEKIMSLIDEIQSQIETISNENNINLIAINENFNSLCNFILTDYDENIMQISKTQDEVLSEHCEKLQSLKILGMDIFTAHSIEKPLHEHTRPEASVIKALPLLDYPKQFQIYRDAENKSKDDTSNSRTCIPNLSTNENFPLSQFSPKTPVPVPDQPLPKVLIPKSINSAKSNRSKTLPNTEGTGRESQNNLKRRFTTEPILKGEETENNDILQNKKLHQ
SIO_010081: YBL063W
subclass of: SO_0000673
so part of: YBL063W
location: 101886..105221
location: region:101886-105221:1
so has part: feature:101886-105221:1:exon

NP_009490.1
type: Protein
SIO_000068: ncbiprotein

S000000159
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:101886-105221:1:exon

YBL061C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CAL2
alternative label: CHS4
alternative label: CSD4
gene: SKT5
locus tag: YBL061C
gene synonym: CAL2; CHS4; CSD4
so part of: sequence
location: complement(<105316..>107406)
location: region:105316-107406:-1
so has part: feature:105316-107406:-1:exon
subclass of: SO_0000010

852218
type: Gene
SIO_000068: ncbigene

position:105316:-1
position: 105316
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:107406:-1
position: 107406
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:105316-107406:-1:exon

YBL061C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CAL2
alternative label: CHS4
alternative label: CSD4
gene: SKT5
locus tag: YBL061C
gene synonym: CAL2; CHS4; CSD4
product: Skt5p
transcript id: NM_001178301.1
SIO_010081: YBL061C
subclass of: SO_0000673
so part of: YBL061C
location: complement(<105316..>107406)
location: region:105316-107406:-1
so has part: feature:105316-107406:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:105316-107406:-1:exon

YBL061C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CAL2
alternative label: CHS4
alternative label: CSD4
gene: SKT5
locus tag: YBL061C
gene synonym: CAL2; CHS4; CSD4
experiment: EXISTENCE:direct assay:GO:0000131 incipient cellular bud site [PMID:15470103]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:15470103|PMID:9314530|PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0008047 enzyme activator activity [PMID:9234668]
experiment: EXISTENCE:mutant phenotype:GO:0034221 fungal-type cell wall chitin biosynthetic process [PMID:17142567|PMID:9234668]
note: Activator of Chs3p (chitin synthase III) during vegetative growth; recruits Chs3p to the bud neck via interaction with Bni4p; SKT5 has a paralog, SHC1, that arose from the whole genome duplication
codon start: 1
product: Skt5p
translation: MASSPQVHPYKKHLMQSQHINFDNRGLQFQNSSLKVGQDFSDNKENRENRDNEDFSTADLPKRSANQPLINEHLRAASVPLLSNDIGNSQEEDFVPVPPPQLHLNNSNNTSLSSLGSTPTNSPSPGALRQTNSSTSLTKEQIKKRTRSVDLSHMYLLNGSSDTQLTATNESVADLSHQMISRYLGGKNNTSLVPRLKTIEMYRQNVKKSKDPEVLFQYAQYMLQTALTIESSNALVQDSDKEGNVSQSDLKLQFLKEAQSYLKKLSIKGYSDAQYLLADGYSSGAFGKIENKEAFVLFQAAAKHGHIESAYRASHCLEEGLGTTRDSRKSVNFLKFAASRNHPSAMYKLGLYSFYGRMGLPTDVNTKLNGVKWLSRAAARANELTAAAPYELAKIYHEGFLDVVIPDEKYAMELYIQAASLGHVPSATLLAQIYETGNDTVGQDTSLSVHYYTQAALKGDSVAMLGLCAWYLLGAEPAFEKDENEAFQWALRAANAGLPKAQFTLGYFYEHGKGCDRNMEYAWKWYEKAAGNEDKRAINKLRSRDGGLASIGKKQHKKNKSISTLNLFSTVDSQTSNVGSNSRVSSKSETFFTGNPKRDREPQGLQINMNSNTNRNGIKTGSDTSIRKSSSSAKGMSREVAEQSMAAKQEVSLSNMGSSNMIRKDFPAVKTESKKPTSLKNKKDKQGKKKKDCVIM
SIO_010081: YBL061C
subclass of: SO_0000673
so part of: YBL061C
location: complement(105316..107406)
location: region:105316-107406:-1
so has part: feature:105316-107406:-1:exon

NP_009492.1
type: Protein
SIO_000068: ncbiprotein

S000000157
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:105316-107406:-1:exon

YBL060W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: YEL1
locus tag: YBL060W
so part of: sequence
location: <107932..>109995
location: region:107932-109995:1
so has part: feature:107932-109995:1:exon
subclass of: SO_0000010

852219
type: Gene
SIO_000068: ncbigene

position:107932:1
position: 107932
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:109995:1
position: 109995
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:107932-109995:1:exon

YBL060W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: YEL1
locus tag: YBL060W
product: Arf family guanine nucleotide exchange factor YEL1
transcript id: NM_001178300.1
SIO_010081: YBL060W
subclass of: SO_0000673
so part of: YBL060W
location: <107932..>109995
location: region:107932-109995:1
so has part: feature:107932-109995:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:107932-109995:1:exon

YBL060W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: YEL1
locus tag: YBL060W
experiment: EXISTENCE:direct assay:GO:0005085 guanyl-nucleotide exchange factor activity [PMID:17786213]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005934 cellular bud tip [PMID:17786213]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:17786213|PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0008104 protein localization [PMID:18397879]
experiment: EXISTENCE:mutant phenotype:GO:0010513 positive regulation of phosphatidylinositol biosynthetic process [PMID:18208507]
experiment: EXISTENCE:mutant phenotype:GO:0051666 actin cortical patch localization [PMID:18397879]
note: Guanine nucleotide exchange factor specific for Arf3p; localized to the bud neck and tip; required for localization of Arf3p to the bud neck and tip
codon start: 1
product: Arf family guanine nucleotide exchange factor YEL1
translation: MCASLNEVKKNDTYGVSQKGYNDNFSESEGVLHGSKSMPTSMKNMLQSPTMVNMCDILQNKEAANDEKPVIPTTDTATAGTGTEDISSTQSEETDQNSHLIASEILEGTFKDVSYKEYANFLGNDNNNQVLTEFVKLLSPLPSSLLETLFNLSKSIYFIAEAQNIDRILECLSIEWIACHPNTHWKSGYKSCHIVLFSLLILNSDLHNNFQVDHKKIKFSMVAFINNTLRALREENEYEELKIYSREHLIIEELSEYYKTLNETPLPLCTESRTSINISDNQSSLKRFSTLGSREFSTSNLRSVNSNSTTLYSRDGQVSVREMSAKSNKNFHNNHPMDALYLKESFDDGLITENGSSWFMDDLILISKKSLPRKYSKRDKDQVAAPKMTSKRNKSFFGWLKPSKTTTLIEHTSRRTSLSYLNKDSEWERVKIQVKEGRIFIFKIKPDVKDIIQSSETDSATIDYFKDISSSYFAYSLLEAEAHVVQDNIIIGSGAMKSNVCNKNTKRKSGNFTVSFPENINGPKLVLEFQTRSVEEAHKFMDCINFWAGRISPVPLTQFEAVSNAEYGWSDKILTEHASLNLKNIVVSEWKPLLGLELLYEDAKDVEMVELKERLKELMNFTRQLGIWIDKHNEIKDKLVEIWSFDDNYFEAVMNNWNSRYLYMNNQYKKRLSYLKALQKAMGSVQF
SIO_010081: YBL060W
subclass of: SO_0000673
so part of: YBL060W
location: 107932..109995
location: region:107932-109995:1
so has part: feature:107932-109995:1:exon

NP_009493.1
type: Protein
SIO_000068: ncbiprotein

S000000156
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:107932-109995:1:exon

YBL059C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CMC2
locus tag: YBL059C-A
so part of: sequence
location: complement(<110125..>110539)
location: region:110125-110539:-1
so has part: feature:110125-110539:-1:exon
subclass of: SO_0000010

852220
type: Gene
SIO_000068: ncbigene

position:110125:-1
position: 110125
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:110539:-1
position: 110539
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:110125-110539:-1:exon

YBL059C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CMC2
locus tag: YBL059C-A
product: Cmc2p
transcript id: NM_001184440.1
SIO_010081: YBL059C-A
subclass of: SO_0000673
so part of: YBL059C-A
location: complement(join(<110125..110420,110506..>110539))
location: region:110125-110539:-1
so has part: feature:110506-110539:-1:exon
so has part: feature:110125-110420:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:110506-110539:-1:exon

position:110506:-1
position: 110506
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:110125-110420:-1:exon

position:110420:-1
position: 110420
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YBL059C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CMC2
locus tag: YBL059C-A
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005758 mitochondrial intermembrane space [PMID:19703468]
experiment: EXISTENCE:mutant phenotype:GO:0033108 mitochondrial respiratory chain complex assembly [PMID:19703468]
note: Protein involved in respiratory chain complex assembly or maintenance; protein of the mitochondrial intermembrane space; contains twin Cx9C motifs that can form coiled coil-helix-coiled-coil helix fold
codon start: 1
product: Cmc2p
translation: MHPQLEAERFHSCLDFINALDKCHQKEYYKRIFGLCNNEKDALNKCLKEASLNNKKRAVIESRIKRADVEKRWKKIEEEEYGEDAILKTILDRQYAKKKQESDNDANSK
SIO_010081: YBL059C-A
subclass of: SO_0000673
so part of: YBL059C-A
location: complement(join(110125..110420,110506..110539))
location: region:110125-110539:-1
so has part: feature:110506-110539:-1:exon
so has part: feature:110125-110420:-1:exon

NP_031358.1
type: Protein
SIO_000068: ncbiprotein

S000007488
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:110506-110539:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:110125-110420:-1:exon

YBL059W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: IAI11
locus tag: YBL059W
so part of: sequence
location: <110594..>111244
location: region:110594-111244:1
so has part: feature:110594-111244:1:exon
subclass of: SO_0000010

852221
type: Gene
SIO_000068: ncbigene

position:110594:1
position: 110594
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:111244:1
position: 111244
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:110594-111244:1:exon

YBL059W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: IAI11
locus tag: YBL059W
product: Iai11p
transcript id: NM_001178299.1
SIO_010081: YBL059W
subclass of: SO_0000673
so part of: YBL059W
location: join(<110594..110879,110949..>111244)
location: region:110594-111244:1
so has part: feature:110594-110879:1:exon
so has part: feature:110949-111244:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:110594-110879:1:exon

position:110879:1
position: 110879
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:110949-111244:1:exon

position:110949:1
position: 110949
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YBL059W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: IAI11
locus tag: YBL059W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095|PMID:16823961|PMID:26928762]
note: Putative mitochondrial hypothetical protein; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; IAI11 has a paralog, YER093C-A, that arose from the whole genome duplication
codon start: 1
product: Iai11p
translation: MLLDAQRFFNRSFSINVICELKHNVNTRRKFEIKDWPTIMLVSRNDKPKISSEEVTHFIDDYKKRRKTQMTRFFGITIFTLITCRIAMKKMITAKVPLNTFQANYASRTQTITHTQKSLAGSLLAATGMTLGIFGMGITGTCWSWDVSSFQELKQRLERRANNEFVVTNMPLDKRSQQVVDSLVKTHNSSLCK
SIO_010081: YBL059W
subclass of: SO_0000673
so part of: YBL059W
location: join(110594..110879,110949..111244)
location: region:110594-111244:1
so has part: feature:110594-110879:1:exon
so has part: feature:110949-111244:1:exon

NP_009494.1
type: Protein
SIO_000068: ncbiprotein

S000000155
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:110594-110879:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:110949-111244:1:exon

YBL058W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: UBX1
gene: SHP1
locus tag: YBL058W
gene synonym: UBX1
so part of: sequence
location: <111437..>112708
location: region:111437-112708:1
so has part: feature:111437-112708:1:exon
subclass of: SO_0000010

852222
type: Gene
SIO_000068: ncbigene

position:111437:1
position: 111437
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:112708:1
position: 112708
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:111437-112708:1:exon

YBL058W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: UBX1
gene: SHP1
locus tag: YBL058W
gene synonym: UBX1
product: protein phosphatase regulator SHP1
transcript id: NM_001178298.1
SIO_010081: YBL058W
subclass of: SO_0000673
so part of: YBL058W
location: <111437..>112708
location: region:111437-112708:1
so has part: feature:111437-112708:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:111437-112708:1:exon

YBL058W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: UBX1
gene: SHP1
locus tag: YBL058W
gene synonym: UBX1
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0036435 K48-linked polyubiquitin modification-dependent protein binding [PMID:28525741]
experiment: EXISTENCE:mutant phenotype:GO:0000045 autophagosome assembly [PMID:20855502]
experiment: EXISTENCE:mutant phenotype:GO:0005977 glycogen metabolic process [PMID:7891699]
experiment: EXISTENCE:mutant phenotype:GO:0019888 protein phosphatase regulator activity [PMID:23418575|PMID:7891699]
experiment: EXISTENCE:mutant phenotype:GO:0030433 ubiquitin-dependent ERAD pathway [PMID:21148305]
experiment: EXISTENCE:mutant phenotype:GO:0030437 ascospore formation [PMID:7891699]
experiment: EXISTENCE:mutant phenotype:GO:0031134 sister chromatid biorientation [PMID:20483956]
experiment: EXISTENCE:mutant phenotype:GO:0034727 piecemeal microautophagy of the nucleus [PMID:20855502]
experiment: EXISTENCE:mutant phenotype:GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process [PMID:15258615]
note: Substrate adaptor for Cdc48p; ubiquitin regulatory X (UBX) and Ub-associated (UBA) domain-containing protein that acts as a substrate recruiting cofactor; K48-specific Ub chain binding protein involved in ER-associated degradation (ERAD); positively regulates Glc7p protein phosphatase activity to promote growth and mitotic progression in complex with Cdc48p; regulated by nuclear Ub-dependent degradation (INMAD pathway) independent of the Asi and Doa10 complexes; homolog of human p47 (NSFL1C)
codon start: 1
product: protein phosphatase regulator SHP1
translation: MAEIPDETIQQFMALTNVSHNIAVQYLSEFGDLNEALNSYYASQTDDQKDRREEAHWNRQQEKALKQEAFSTNSSNKAINTEHVGGLCPKPGSSQGSNEYLKRKGSTSPEPTKGSSRSGSGNNSRFMSFSDMVRGQADDDDEDQPRNTFAGGETSGLEVTDPSDPNSLLKDLLEKARRGGQMGAENGFRDDEDHEMGANRFTGRGFRLGSTIDAADEVVEDNTSQSQRRPEKVTREITFWKEGFQVADGPLYRYDDPANSFYLSELNQGRAPLKLLDVQFGQEVEVNVYKKLDESYKAPTRKLGGFSGQGQRLGSPIPGESSPAEVPKNETPAAQEQPMPDNEPKQGDTSIQIRYANGKREVLHCNSTDTVKFLYEHVTSNANTDPSRNFTLNYAFPIKPISNDETTLKDADLLNSVVVQRWA
SIO_010081: YBL058W
subclass of: SO_0000673
so part of: YBL058W
location: 111437..112708
location: region:111437-112708:1
so has part: feature:111437-112708:1:exon

NP_009495.1
type: Protein
SIO_000068: ncbiprotein

S000000154
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:111437-112708:1:exon

YBL057C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PTH2
locus tag: YBL057C
so part of: sequence
location: complement(<112801..>113427)
location: region:112801-113427:-1
so has part: feature:112801-113427:-1:exon
subclass of: SO_0000010

852223
type: Gene
SIO_000068: ncbigene

position:112801:-1
position: 112801
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:113427:-1
position: 113427
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:112801-113427:-1:exon

YBL057C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PTH2
locus tag: YBL057C
product: aminoacyl-tRNA hydrolase
transcript id: NM_001178297.2
SIO_010081: YBL057C
subclass of: SO_0000673
so part of: YBL057C
location: complement(<112801..>113427)
location: region:112801-113427:-1
so has part: feature:112801-113427:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:112801-113427:-1:exon

YBL057C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PTH2
locus tag: YBL057C
EC number: 3.1.1.29
experiment: EXISTENCE:direct assay:GO:0004045 aminoacyl-tRNA hydrolase activity [PMID:12799450]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005741 mitochondrial outer membrane [PMID:16407407]
experiment: EXISTENCE:direct assay:GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process [PMID:17082762]
experiment: EXISTENCE:genetic interaction:GO:0004045 aminoacyl-tRNA hydrolase activity [PMID:12475929]
experiment: EXISTENCE:mutant phenotype:GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process [PMID:17082762]
note: One of two mitochondrially-localized peptidyl-tRNA hydrolases; negatively regulates the ubiquitin-proteasome pathway via interactions with ubiquitin-like ubiquitin-associated proteins; dispensable for cell growth; see also PTH1
codon start: 1
product: aminoacyl-tRNA hydrolase
translation: MEKMTVSSNYTIALWATFTAISFAVGYQLGTSNASSTKKSSATLLRSKEMKEGKLHNDTDEEESESEDESDEDEDIESTSLNDIPGEVRMALVIRQDLGMTKGKIAAQCCHAALSCFRHIATNPARASYNPIMTQRWLNAGQAKITLKCPDKFTMDELYAKAISLGVNAAVIHDAGRTQIAAGSATVLGLGPAPKAVLDQITGDLKLY
SIO_010081: YBL057C
subclass of: SO_0000673
so part of: YBL057C
location: complement(112801..113427)
location: region:112801-113427:-1
so has part: feature:112801-113427:-1:exon

NP_009496.2
type: Protein
SIO_000068: ncbiprotein

S000000153
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:112801-113427:-1:exon

YBL056W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PTC3
locus tag: YBL056W
so part of: sequence
location: <113762..>115168
location: region:113762-115168:1
so has part: feature:113762-115168:1:exon
subclass of: SO_0000010

852224
type: Gene
SIO_000068: ncbigene

position:113762:1
position: 113762
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:115168:1
position: 115168
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:113762-115168:1:exon

YBL056W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PTC3
locus tag: YBL056W
product: type 2C protein phosphatase PTC3
transcript id: NM_001178296.2
SIO_010081: YBL056W
subclass of: SO_0000673
so part of: YBL056W
location: <113762..>115168
location: region:113762-115168:1
so has part: feature:113762-115168:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:113762-115168:1:exon

YBL056W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PTC3
locus tag: YBL056W
EC number: 3.1.3.16
experiment: EXISTENCE:direct assay:GO:0004722 protein serine/threonine phosphatase activity [PMID:10580002]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:12477803|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:12477803|PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity [PMID:10580002]
note: Type 2C protein phosphatase (PP2C); dephosphorylates Hog1p (see also Ptc2p) to limit maximal kinase activity induced by osmotic stress; dephosphorylates T169 phosphorylated Cdc28p (see also Ptc2p); role in DNA damage checkpoint inactivation; PTC3 has a paralog, PTC2, that arose from the whole genome duplication
codon start: 1
product: type 2C protein phosphatase PTC3
translation: MGQILSNPIIDKEHHSGTDCLTAFGLCAMQGWRMSMEDAHIVEPNLLAESDEEHLAFYGIFDGHGGSSVAEFCGSKMISILKKQESFKSGMLEQCLIDTFLATDVELLKDEKLKDDHSGCTATVILVSQLKKLLICANSGDSRTVLSTGGNSKAMSFDHKPTLLSEKSRIVAADGFVEMDRVNGNLALSRAIGDFEFKSNTKLGPHEQVVTCVPDIICHNLNYDEDEFVILACDGIWDCLTSQECVDLVHYGISQGNMTLSDISSRIVDVCCSPTTEGSGIGCDNMSISIVALLKENESESQWFERMRSKNYNIQTSFVQRRKSIFDFHDFSDDDNEVFAITTKKLQDRLNRSKDNDDMEIDDLDTELGSSATPSKLSGEDRTGPIDLFSLEALLEAGIQIRQRPSSDSDGNTSYFHGASLSDMLASLSNAAAGETEPNDADDNDDNDGEENGKNENAKKGSKIEEIE
SIO_010081: YBL056W
subclass of: SO_0000673
so part of: YBL056W
location: 113762..115168
location: region:113762-115168:1
so has part: feature:113762-115168:1:exon

NP_009497.2
type: Protein
SIO_000068: ncbiprotein

S000000152
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:113762-115168:1:exon

YBL055C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBL055C
so part of: sequence
location: complement(<115573..>116829)
location: region:115573-116829:-1
so has part: feature:115573-116829:-1:exon
subclass of: SO_0000010

852225
type: Gene
SIO_000068: ncbigene

position:115573:-1
position: 115573
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:116829:-1
position: 116829
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:115573-116829:-1:exon

YBL055C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBL055C
product: 3'-5'-exodeoxyribonuclease
transcript id: NM_001178295.1
SIO_010081: YBL055C
subclass of: SO_0000673
so part of: YBL055C
location: complement(<115573..>116829)
location: region:115573-116829:-1
so has part: feature:115573-116829:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:115573-116829:-1:exon

YBL055C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBL055C
experiment: EXISTENCE:direct assay:GO:0004519 endonuclease activity [PMID:15657035]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0008296 3'-5'-exodeoxyribonuclease activity [PMID:15657035]
experiment: EXISTENCE:mutant phenotype:GO:0006309 apoptotic DNA fragmentation [PMID:15657035]
experiment: EXISTENCE:mutant phenotype:GO:0034599 cellular response to oxidative stress [PMID:15657035]
note: 3'-->5' exonuclease and endonuclease with a possible role in apoptosis; has similarity to mammalian and C. elegans apoptotic nucleases
codon start: 1
product: 3'-5'-exodeoxyribonuclease
translation: MWGILLKSSNKSCSRLWKPILTQYYSMTSTATDSPLKYYDIGLNLTDPMFHGIYNGKQYHPADYVKLLERAAQRHVKNALVTGSSIAESQSAIELVSSVKDLSPLKLYHTIGVHPCCVNEFADASQGDKASASIDNPSMDEAYNESLYAKVISNPSFAQGKLKELYDLMNQQAKPHDTSFRSIGEIGLDYDRFHYSSKEMQKVFFEEQLKISCLNDKLSSYPLFLHMRSACDDFVQILERFIAGFTDERDTFQLQKLGASSSSGFYKFHPDRKLVVHSFTGSAIDLQKLLNLSPNIFIGVNGCSLRTEENLAVVKQIPTERLLLETDAPWCEIKRTHASFQYLAKYQEVRDFEYPAFKSVKKNKLADKLNAEELYMVKGRNEPCNMEQVAIVVSEVKDVDLATLIDTTWKTTCKIFGE
SIO_010081: YBL055C
subclass of: SO_0000673
so part of: YBL055C
location: complement(115573..116829)
location: region:115573-116829:-1
so has part: feature:115573-116829:-1:exon

NP_009498.1
type: Protein
SIO_000068: ncbiprotein

S000000151
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:115573-116829:-1:exon

YBL054W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PBF1
gene: TOD6
locus tag: YBL054W
gene synonym: PBF1
so part of: sequence
location: <117589..>119166
location: region:117589-119166:1
so has part: feature:117589-119166:1:exon
subclass of: SO_0000010

852226
type: Gene
SIO_000068: ncbigene

position:117589:1
position: 117589
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:119166:1
position: 119166
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:117589-119166:1:exon

YBL054W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PBF1
gene: TOD6
locus tag: YBL054W
gene synonym: PBF1
product: Tod6p
transcript id: NM_001178294.1
SIO_010081: YBL054W
subclass of: SO_0000673
so part of: YBL054W
location: <117589..>119166
location: region:117589-119166:1
so has part: feature:117589-119166:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:117589-119166:1:exon

YBL054W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PBF1
gene: TOD6
locus tag: YBL054W
gene synonym: PBF1
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:19158363]
experiment: EXISTENCE:direct assay:GO:0070210 Rpd3L-Expanded complex [PMID:19040720]
experiment: EXISTENCE:mutant phenotype:GO:0006357 regulation of transcription by RNA polymerase II [PMID:19158363]
note: PAC motif binding protein involved in rRNA and ribosome biogenesis; subunit of the RPD3L histone deacetylase complex; Myb-like HTH transcription factor; hypophosphorylated by rapamycin treatment in a Sch9p-dependent manner; activated in stochastic pulses of nuclear localization
codon start: 1
product: Tod6p
translation: MTLPKLSSVSVSSGHVSANSHGFSILSKHPHPNNLVHSHSLSHTNAKSHLPISSTSTKENSTNKEEAESLKKNNPSSWDPSDDIKLRHLKEIKNLGWKEIAHHFPNRTPNACQFRWRRLKSGNLKSNKTAVIDINKLFGVYATGDATPSAGTPSAEEAVKEEAVEDEDITAGSSAIEDSPPDFKPLVKPKYMDRKLITQRSTSTFSDHEPQHTKPRKLFVKPRSFSHSITTNTPNVKTAQQTNLSLYNTTSAKTNKAVNSNDYENIGLVPKIIIRSRRNSFIPSTQIPHSTTKTRKNSHSVISSRRSSFNMMHSRRSSFNSHAPTEPISRRASLVVSPYMSPRRLSTSQSVHYHPQHQYYLNPIASPNCKTDHANDKITHTRTFLDMQKFANKHPWSREDDEVLLNNTKDKQNHLSPLEISIVLPNNRSELEIQQRMDYLKRKGRVSGFHTNEGCKDEEEEDDIDPLHKENGINTPSQQSQNYGMLEAKHDNPKSSELSSMTSANDIRNEQDELPGINSIFKNIF
SIO_010081: YBL054W
subclass of: SO_0000673
so part of: YBL054W
location: 117589..119166
location: region:117589-119166:1
so has part: feature:117589-119166:1:exon

NP_009499.1
type: Protein
SIO_000068: ncbiprotein

S000000150
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:117589-119166:1:exon

YBL052C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: KAT6
gene: SAS3
locus tag: YBL052C
gene synonym: KAT6
so part of: sequence
location: complement(<119379..>121874)
location: region:119379-121874:-1
so has part: feature:119379-121874:-1:exon
subclass of: SO_0000010

852228
type: Gene
SIO_000068: ncbigene

position:119379:-1
position: 119379
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:121874:-1
position: 121874
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:119379-121874:-1:exon

YBL052C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: KAT6
gene: SAS3
locus tag: YBL052C
gene synonym: KAT6
product: histone acetyltransferase
transcript id: NM_001178292.1
SIO_010081: YBL052C
subclass of: SO_0000673
so part of: YBL052C
location: complement(<119379..>121874)
location: region:119379-121874:-1
so has part: feature:119379-121874:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:119379-121874:-1:exon

YBL052C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: KAT6
gene: SAS3
locus tag: YBL052C
gene synonym: KAT6
EC number: 2.3.1.48
experiment: EXISTENCE:direct assay:GO:0004402 histone acetyltransferase activity [PMID:10817755]
experiment: EXISTENCE:direct assay:GO:0033100 NuA3 histone acetyltransferase complex [PMID:10817755|PMID:17157260]
experiment: EXISTENCE:direct assay:GO:1990467 NuA3a histone acetyltransferase complex [PMID:25104842]
experiment: EXISTENCE:direct assay:GO:1990468 NuA3b histone acetyltransferase complex [PMID:25104842]
experiment: EXISTENCE:mutant phenotype:GO:0004402 histone acetyltransferase activity [PMID:10817755]
experiment: EXISTENCE:mutant phenotype:GO:0030466 silent mating-type cassette heterochromatin formation [PMID:11731479]
experiment: EXISTENCE:mutant phenotype:GO:0031509 subtelomeric heterochromatin formation [PMID:11731479]
note: Histone acetyltransferase catalytic subunit of NuA3 complex; acetylates histone H3, involved in transcriptional silencing; homolog of the mammalian MOZ proto-oncogene; mutant has aneuploidy tolerance; sas3gcn5 double mutation is lethal
codon start: 1
product: histone acetyltransferase
translation: MSLTANDESPKPKKNALLKNLEIDDLIHSQFVRSDTNGHRTTRRLFNSDASISHRIRGSVRSDKGLNKIKKGLISQQSKLASENSSQNIVNRDNKMGAVSFPIIEPNIEVSEELKVRIKYDSIKFFNFERLISKSSVIAPLVNKNITSSGPLIGFQRRVNRLKQTWDLATENMEYPYSSDNTPFRDNDSWQWYVPYGGTIKKMKDFSTKRTLPTWEDKIKFLTFLENSKSATYINGNVSLCNHNETDQENEDRKKRKGKVPRIKNKVWFSQIEYIVLRNYEIKPWYTSPFPEHINQNKMVFICEFCLKYMTSRYTFYRHQLKCLTFKPPGNEIYRDGKLSVWEIDGRENVLYCQNLCLLAKCFINSKTLYYDVEPFIFYILTEREDTENHPYQNAAKFHFVGYFSKEKFNSNDYNLSCILTLPIYQRKGYGQFLMEFSYLLSRKESKFGTPEKPLSDLGLLTYRTFWKIKCAEVLLKLRDSARRRSNNKNEDTFQQVSLNDIAKLTGMIPTDVVFGLEQLQVLYRHKTRSLSSLDDFNYIIKIDSWNRIENIYKTWSSKNYPRVKYDKLLWEPIILGPSFGINGMMNLEPTALADEALTNETMAPVISNNTHIENYNNSRAHNKRRRRRRRSSEHKTSKLHVNNIIEPEVPATDFFEDTVSSLTEYMCDYKNTNNDRLIYQAEKRVLESIHDRKGIPRSKFSTETHWELCFTIKNSETPLGNHAARRNDTGISSLEQDEVENDVDTELYVGENAKEDEDEDEDFTLDDDIEDEQISEENDEEEDTYEEDSDDDEDGKRKGQEQDENDIESHIRKERVRKRRKITLIEDDEE
SIO_010081: YBL052C
subclass of: SO_0000673
so part of: YBL052C
location: complement(119379..121874)
location: region:119379-121874:-1
so has part: feature:119379-121874:-1:exon

NP_009501.1
type: Protein
SIO_000068: ncbiprotein

S000000148
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:119379-121874:-1:exon

YBL051C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MDT1
gene: PIN4
locus tag: YBL051C
gene synonym: MDT1
so part of: sequence
location: complement(<122753..>124759)
location: region:122753-124759:-1
so has part: feature:122753-124759:-1:exon
subclass of: SO_0000010

852229
type: Gene
SIO_000068: ncbigene

position:122753:-1
position: 122753
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:124759:-1
position: 124759
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:122753-124759:-1:exon

YBL051C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MDT1
gene: PIN4
locus tag: YBL051C
gene synonym: MDT1
product: Pin4p
transcript id: NM_001178291.1
SIO_010081: YBL051C
subclass of: SO_0000673
so part of: YBL051C
location: complement(<122753..>124759)
location: region:122753-124759:-1
so has part: feature:122753-124759:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:122753-124759:-1:exon

YBL051C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MDT1
gene: PIN4
locus tag: YBL051C
gene synonym: MDT1
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:23222640|PMID:14562095]
experiment: EXISTENCE:genetic interaction:GO:0000077 DNA damage checkpoint signaling [PMID:15024067]
experiment: EXISTENCE:mutant phenotype:GO:0000086 G2/M transition of mitotic cell cycle [PMID:15024067]
experiment: EXISTENCE:physical interaction:GO:0000077 DNA damage checkpoint signaling [PMID:15024067]
note: Protein involved in G2/M phase progression and response to DNA damage; interacts with Rad53p; contains an RNA recognition motif, a nuclear localization signal, and several SQ/TQ cluster domains; hyperphosphorylated in response to DNA damage
codon start: 1
product: Pin4p
translation: METSSFENAPPAAINDAQDNNINTETNDQETNQQSIETRDAIDKENGVQTETGENSAKNAEQNVSSTNLNNAPTNGALDDDVIPNAIVIKNIPFAIKKEQLLDIIEEMDLPLPYAFNYHFDNGIFRGLAFANFTTPEETTQVITSLNGKEISGRKLKVEYKKMLPQAERERIEREKREKRGQLEEQHRSSSNLSLDSLSKMSGSGNNNTSNNQLFSTLMNGINANSMMNSPMNNTINNNSSNNNNSGNIILNQPSLSAQHTSSSLYQTNVNNQAQMSTERFYAPLPSTSTLPLPPQQLDFNDPDTLEIYSQLLLFKDREKYYYELAYPMGISASHKRIINVLCSYLGLVEVYDPRFIIIRRKILDHANLQSHLQQQGQMTSAHPLQPNSTGGSMNRSQSYTSLLQAHAAAAANSISNQAVNNSSNSNTINSNNGNGNNVIINNNSASSTPKISSQGQFSMQPTLTSPKMNIHHSSQYNSADQPQQPQPQTQQNVQSAAQQQQSFLRQQATLTPSSRIPSGYSANHYQINSVNPLLRNSQISPPNSQIPINSQTLSQAQPPAQSQTQQRVPVAYQNASLSSQQLYNLNGPSSANSQSQLLPQHTNGSVHSNFSYQSYHDESMLSAHNLNSADLIYKSLSHSGLDDGLEQGLNRSLSGLDLQNQNKKNLW
SIO_010081: YBL051C
subclass of: SO_0000673
so part of: YBL051C
location: complement(122753..124759)
location: region:122753-124759:-1
so has part: feature:122753-124759:-1:exon

NP_009502.1
type: Protein
SIO_000068: ncbiprotein

S000000147
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:122753-124759:-1:exon

YBL050W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RNS3
gene: SEC17
locus tag: YBL050W
gene synonym: RNS3
so part of: sequence
location: <125125..>126119
location: region:125125-126119:1
so has part: feature:125125-126119:1:exon
subclass of: SO_0000010

852230
type: Gene
SIO_000068: ncbigene

position:125125:1
position: 125125
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:126119:1
position: 126119
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:125125-126119:1:exon

YBL050W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RNS3
gene: SEC17
locus tag: YBL050W
gene synonym: RNS3
product: Sec17p
transcript id: NM_001178290.1
SIO_010081: YBL050W
subclass of: SO_0000673
so part of: YBL050W
location: join(<125125..125154,125271..>126119)
location: region:125125-126119:1
so has part: feature:125125-125154:1:exon
so has part: feature:125271-126119:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:125125-125154:1:exon

position:125154:1
position: 125154
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:125271-126119:1:exon

position:125271:1
position: 125271
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YBL050W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RNS3
gene: SEC17
locus tag: YBL050W
gene synonym: RNS3
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:19001347|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0001671 ATPase activator activity [PMID:10387016]
experiment: EXISTENCE:direct assay:GO:0005483 soluble NSF attachment protein activity [PMID:11994317]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:8636207]
experiment: EXISTENCE:direct assay:GO:0035494 SNARE complex disassembly [PMID:18650938|PMID:9425154]
experiment: EXISTENCE:direct assay:GO:0042144 vacuole fusion, non-autophagic [PMID:8670830|PMID:9685264]
experiment: EXISTENCE:direct assay:GO:0048280 vesicle fusion with Golgi apparatus [PMID:1601878]
experiment: EXISTENCE:mutant phenotype:GO:0006914 autophagy [PMID:11694599]
experiment: EXISTENCE:physical interaction:GO:0005483 soluble NSF attachment protein activity [PMID:10387016]
experiment: EXISTENCE:physical interaction:GO:0031201 SNARE complex [PMID:10397773]
note: Alpha-SNAP cochaperone; SNARE-complex adaptor for Sec18 (NSF) during the disassembly of postfusion cis-SNARE complexes; stimulates the ATPase activity of Sec18p; peripheral membrane protein required for vesicular transport between ER and Golgi, the 'priming' step in homotypic vacuole fusion, and autophagy; similar to mammalian alpha-SNAP
codon start: 1
product: Sec17p
translation: MSDPVELLKRAEKKGVPSSGFMKLFSGSDSYKFEEAADLCVQAATIYRLRKELNLAGDSFLKAADYQKKAGNEDEAGNTYVEAYKCFKSGGNSVNAVDSLENAIQIFTHRGQFRRGANFKFELGEILENDLHDYAKAIDCYELAGEWYAQDQSVALSNKCFIKCADLKALDGQYIEASDIYSKLIKSSMGNRLSQWSLKDYFLKKGLCQLAATDAVAAARTLQEGQSEDPNFADSRESNFLKSLIDAVNEGDSEQLSEHCKEFDNFMRLDKWKITILNKIKESIQQQEDDLL
SIO_010081: YBL050W
subclass of: SO_0000673
so part of: YBL050W
location: join(125125..125154,125271..126119)
location: region:125125-126119:1
so has part: feature:125125-125154:1:exon
so has part: feature:125271-126119:1:exon

NP_009503.1
type: Protein
SIO_000068: ncbiprotein

S000000146
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:125125-125154:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:125271-126119:1:exon

YBL049W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MOH1
locus tag: YBL049W
so part of: sequence
location: <126828..>127244
location: region:126828-127244:1
so has part: feature:126828-127244:1:exon
subclass of: SO_0000010

852231
type: Gene
SIO_000068: ncbigene

position:126828:1
position: 126828
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:127244:1
position: 127244
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:126828-127244:1:exon

YBL049W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MOH1
locus tag: YBL049W
product: Moh1p
transcript id: NM_001178289.1
SIO_010081: YBL049W
subclass of: SO_0000673
so part of: YBL049W
location: <126828..>127244
location: region:126828-127244:1
so has part: feature:126828-127244:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:126828-127244:1:exon

YBL049W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MOH1
locus tag: YBL049W
note: hypothetical protein, essential for stationary phase survival; not required for growth on nonfermentable carbon sources; possibly linked with vacuolar transport
codon start: 1
product: Moh1p
translation: MGLRYSIYIENPLSSPSSSYKSINDPLFHSQHRSQKNVSFITYGCRHCKTHLSSSFQIISRDYRGRTGTAYLMNKVVNVVEGKVEQRRMLTGDYLVCDILCHWCKRNVGWKYLQSSNDDQQYKEGKFILELKNICKCT
SIO_010081: YBL049W
subclass of: SO_0000673
so part of: YBL049W
location: 126828..127244
location: region:126828-127244:1
so has part: feature:126828-127244:1:exon

NP_009504.1
type: Protein
SIO_000068: ncbiprotein

S000000145
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:126828-127244:1:exon

YBL048W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RRT1
locus tag: YBL048W
so part of: sequence
location: <127299..>127610
location: region:127299-127610:1
so has part: feature:127299-127610:1:exon
subclass of: SO_0000010

852232
type: Gene
SIO_000068: ncbigene

position:127299:1
position: 127299
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:127610:1
position: 127610
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:127299-127610:1:exon

YBL048W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RRT1
locus tag: YBL048W
product: Rrt1p
transcript id: NM_001348869.1
SIO_010081: YBL048W
subclass of: SO_0000673
so part of: YBL048W
location: <127299..>127610
location: region:127299-127610:1
so has part: feature:127299-127610:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:127299-127610:1:exon

YBL048W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RRT1
locus tag: YBL048W
note: hypothetical protein; conserved across S. cerevisiae strains; identified in a screen for mutants with increased levels of rDNA transcription
codon start: 1
product: Rrt1p
translation: MILFKNLVFLPSILIGYISIRVSLLVWVNWVLVWSSCFQVAFIFSLWYFILSIYTFFYSKKIKQIISYEPSYFVFSYRAIDLCPERVLLYFFCIFNNVVFPML
SIO_010081: YBL048W
subclass of: SO_0000673
so part of: YBL048W
location: 127299..127610
location: region:127299-127610:1
so has part: feature:127299-127610:1:exon

NP_001335744.1
type: Protein
SIO_000068: ncbiprotein

S000000144
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:127299-127610:1:exon

YBL047C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: BUD15
gene: EDE1
locus tag: YBL047C
gene synonym: BUD15
so part of: sequence
location: complement(<127895..>132040)
location: region:127895-132040:-1
so has part: feature:127895-132040:-1:exon
subclass of: SO_0000010

852233
type: Gene
SIO_000068: ncbigene

position:127895:-1
position: 127895
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:132040:-1
position: 132040
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:127895-132040:-1:exon

YBL047C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: BUD15
gene: EDE1
locus tag: YBL047C
gene synonym: BUD15
product: Ede1p
transcript id: NM_001178287.1
SIO_010081: YBL047C
subclass of: SO_0000673
so part of: YBL047C
location: complement(<127895..>132040)
location: region:127895-132040:-1
so has part: feature:127895-132040:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:127895-132040:-1:exon

YBL047C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: BUD15
gene: EDE1
locus tag: YBL047C
gene synonym: BUD15
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:25366307]
experiment: EXISTENCE:direct assay:GO:0005934 cellular bud tip [PMID:11452010]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:11452010|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0030479 actin cortical patch [PMID:10954428|PMID:25366307]
experiment: EXISTENCE:direct assay:GO:0043130 ubiquitin binding [PMID:16563434]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:19053807]
experiment: EXISTENCE:genetic interaction:GO:0032467 positive regulation of cytokinesis [PMID:25371407]
experiment: EXISTENCE:mutant phenotype:GO:0006897 endocytosis [PMID:10954428]
experiment: EXISTENCE:mutant phenotype:GO:0030968 endoplasmic reticulum unfolded protein response [PMID:16582425]
experiment: EXISTENCE:mutant phenotype:GO:0032880 regulation of protein localization [PMID:25625208]
experiment: EXISTENCE:mutant phenotype:GO:0044396 actin cortical patch organization [PMID:25366307]
note: Endocytic adaptor; K63-specific Ub-chain binding protein involved in receptor endocytosis; scaffold protein that localizes to nascent endocytic sites after homo-oligomerization and organizes the endocytic machinery; role in autophagy of aberrant clathrin-mediated endocytosis protein condensates; binds membranes in a Ub-dependent manner; interacts with and functions upstream of Cmk2p to suppress stress-induced non-apoptotic cell death; putative cytokinesis regulator; homolog of mammalian Eps15
codon start: 1
product: Ede1p
translation: MASITFRTPLSSQEQAFYNQKFHQLDTEDLGVVTGEAVRPLFASSGLPGQLLSQVWATVDIDNKGFLNLNEFSAALRMIAQLQNAPNQPISAALYESTPTQLASFSINQNPAPMQSGSATGNTNNTDIPALSSNDIAKFSQLFDRTAKGAQTVAGDKAKDIFLKARLPNQTLGEIWALCDRDASGVLDKSEFIMAMYLIQLCMSHHPSMNTPPAVLPTQLWDSIRLEPVVVNQPNRTTPLSANSTGVSSLTRHSTISRLSTGAFSNAASDWSLSFEKKQQFDAIFDSLDKQHAGSLSSAVLVPFFLSSRLNQETLATIWDLADIHNNAEFTKLEFAIAMFLIQKKNAGVELPDVIPNELLQSPALGLYPPNPLPQQQSAPQIAIPSRASKPSLQDMPHQVSAPAVNTQPTVPQVLPQNSNNGSLNDLLALNPSFSSPSPTKAQTVVQNNTNNSFSYDNNNGQATLQQQQPQQPPPLTHSSSGLKKFTPTSNFGQSIIKEEPEEQEQLRESSDTFSAQPPPVPKHASSPVKRTASTTLPQVPNFSVFSMPAGAATSAATGAAVGAAVGAAALGASAFSRSSNNAFKNQDLFADGEASAQLSNATTEMANLSNQVNSLSKQASITNDKKSRATQELKRVTEMKNSIQIKLNNLRSTHDQNVKQTEQLEAQVLQVNKENETLAQQLAVSEANYHAAESKLNELTTDLQESQTKNAELKEQITNLNSMTASLQSQLNEKQQQVKQERSMVDVNSKQLELNQVTVANLQKEIDGLGEKISVYLTKQKELNDYQKTVEEQHAQLQAKYQDLSNKDTDLTDREKQLEERNRQIEEQENLYHQHVSKLQEMFDDLSQRKASFEKADQELKERNIEYANNVRELSERQMNLAMGQLPEDAKDIIAKSASNTDTTTKEATSRGNVHEDTVSKFVETTVENSNLNVNRVKDDEEKTERTESDVFDRDVPTLGSQSDSENANTNNGTQSGNETANPNLTETLSDRFDGDLNEYGIPRSQSLTSSVANNAPQSVRDDVELPETLEERDTINNTANRDNTGNLSHIPGEWEATPATASTDVLSNETTEVIEDGSTTKRANSNEDGESVSSIQESPKISAQPKAKTINEEFPPIQELHIDESDSSSSDDDEFEDTREIPSATVKTLQTPYNAQPTSSLEIHTEQVIKYPAPGTSPSHNEGNSKKASTNSILPVKDEFDDEFAGLEQAAVEEDNGADSESEFENVANAGSMEQFETIDHKDLDDELQMNAFTGTLTSSSNPTIPKPQVQQQSTSDPAQVSNDEWDEIFAGFGNSKAEPTKVATPSIPQQPIPLKNDPIVDASLSKGPIVNRGVATTPKSLAVEELSGMGFTEEEAHNALEKCNWDLEAATNFLLDSA
SIO_010081: YBL047C
subclass of: SO_0000673
so part of: YBL047C
location: complement(127895..132040)
location: region:127895-132040:-1
so has part: feature:127895-132040:-1:exon

NP_009506.1
type: Protein
SIO_000068: ncbiprotein

S000000143
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:127895-132040:-1:exon

YBL046W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: HSM6
gene: PSY4
locus tag: YBL046W
gene synonym: HSM6
so part of: sequence
location: <132424..>133749
location: region:132424-133749:1
so has part: feature:132424-133749:1:exon
subclass of: SO_0000010

852234
type: Gene
SIO_000068: ncbigene

position:132424:1
position: 132424
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:133749:1
position: 133749
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:132424-133749:1:exon

YBL046W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: HSM6
gene: PSY4
locus tag: YBL046W
gene synonym: HSM6
product: Psy4p
transcript id: NM_001178286.1
SIO_010081: YBL046W
subclass of: SO_0000673
so part of: YBL046W
location: <132424..>133749
location: region:132424-133749:1
so has part: feature:132424-133749:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:132424-133749:1:exon

YBL046W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: HSM6
gene: PSY4
locus tag: YBL046W
gene synonym: HSM6
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:16857015|PMID:19520826|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:19520826]
experiment: EXISTENCE:direct assay:GO:0030289 protein phosphatase 4 complex [PMID:16299494|PMID:17517611]
experiment: EXISTENCE:mutant phenotype:GO:0019888 protein phosphatase regulator activity [PMID:16857015]
experiment: EXISTENCE:mutant phenotype:GO:0030289 protein phosphatase 4 complex [PMID:16299494]
experiment: EXISTENCE:mutant phenotype:GO:2000002 negative regulation of DNA damage checkpoint [PMID:16299494]
note: Regulatory subunit of protein phosphatase PP4; presence of Psy4p in the PP4 complex (along with catalytic subunit Pph3p and Psy2p) is required for dephosphorylation of the histone variant H2AX, but not for dephosphorylation of Rad53p, during recovery from the DNA damage checkpoint; localization is cell-cycle dependent and regulated by Cdc28p phosphorylation; required for cisplatin resistance; homolog of mammalian R2
codon start: 1
product: Psy4p
translation: MSSTMLDDVDNNMMGIKSISLYELLSDVVKQGDKTRLVTAGPEQVLPDLIRHITETIPFDLFINLKNEMNDARNLVTRLNWLGKFLNDNFLQNHTFPFTILRICELCYDPFKYYKINELEKFVNALEKCCMVTSSWQVFDKTHGEKQEDDKEKDINFIKNQEDVSLMKIPWMTENNTRELAPFIREIDSIMSVNLGYDDEDEEEGFFDGDEDREMGNKSKRNVLLKDENFMVEEYYEDDCGINDDNSDNKGQNCQSDVTKNNSDDEDDDDNDDDYREDGADEDDEDDDHMGSTDDDEDDDEDRQAGESTKVQNFDKKNETPRKRKPTDLDNFEYDESPSFTNMDLTTPKKYKHTATGRFSIIESPSSSLLNAMDGSNEISSSQEEEKEDAHENHEGRSEGLLPGDELVSPSMSSSQEDKMVAIAGITYRENISSPLGKKSR
SIO_010081: YBL046W
subclass of: SO_0000673
so part of: YBL046W
location: 132424..133749
location: region:132424-133749:1
so has part: feature:132424-133749:1:exon

NP_009507.1
type: Protein
SIO_000068: ncbiprotein

S000000142
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:132424-133749:1:exon

YBL045C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: QCR1
gene: COR1
locus tag: YBL045C
gene synonym: QCR1
so part of: sequence
location: complement(<134143..>135516)
location: region:134143-135516:-1
so has part: feature:134143-135516:-1:exon
subclass of: SO_0000010

852235
type: Gene
SIO_000068: ncbigene

position:134143:-1
position: 134143
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:135516:-1
position: 135516
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:134143-135516:-1:exon

YBL045C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: QCR1
gene: COR1
locus tag: YBL045C
gene synonym: QCR1
product: ubiquinol--cytochrome-c reductase subunit COR1
transcript id: NM_001178285.1
SIO_010081: YBL045C
subclass of: SO_0000673
so part of: YBL045C
location: complement(<134143..>135516)
location: region:134143-135516:-1
so has part: feature:134143-135516:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:134143-135516:-1:exon

YBL045C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: QCR1
gene: COR1
locus tag: YBL045C
gene synonym: QCR1
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:11502169|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005750 mitochondrial respiratory chain complex III [PMID:10873857|PMID:3023384]
experiment: EXISTENCE:direct assay:GO:0008121 ubiquinol-cytochrome-c reductase activity [PMID:3023384]
experiment: EXISTENCE:mutant phenotype:GO:0009060 aerobic respiration [PMID:2174874]
note: Core subunit of the ubiquinol-cytochrome c reductase complex; the ubiquinol-cytochrome c reductase complex (bc1 complex) is a component of the mitochondrial inner membrane electron transport chain
codon start: 1
product: ubiquinol--cytochrome-c reductase subunit COR1
translation: MLRTVTSKTVSNQFKRSLATAVATPKAEVTQLSNGIVVATEHNPSAHTASVGVVFGSGAANENPYNNGVSNLWKNIFLSKENSAVAAKEGLALSSNISRDFQSYIVSSLPGSTDKSLDFLNQSFIQQKANLLSSSNFEATKKSVLKQVQDFEENDHPNRVLEHLHSTAFQNTPLSLPTRGTLESLENLVVADLESFANNHFLNSNAVVVGTGNIKHEDLVNSIESKNLSLQTGTKPVLKKKAAFLGSEVRLRDDTLPKAWISLAVEGEPVNSPNYFVAKLAAQIFGSYNAFEPASRLQGIKLLDNIQEYQLCDNFNHFSLSYKDSGLWGFSTATRNVTMIDDLIHFTLKQWNRLTISVTDTEVERAKSLLKLQLGQLYESGNPVNDANLLGAEVLIKGSKLSLGEAFKKIDAITVKDVKAWAGKRLWDQDIAIAGTGQIEGLLDYMRIRSDMSMMRW
SIO_010081: YBL045C
subclass of: SO_0000673
so part of: YBL045C
location: complement(134143..135516)
location: region:134143-135516:-1
so has part: feature:134143-135516:-1:exon

NP_009508.1
type: Protein
SIO_000068: ncbiprotein

S000000141
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:134143-135516:-1:exon

YBL044W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBL044W
so part of: sequence
location: <135998..>136366
location: region:135998-136366:1
so has part: feature:135998-136366:1:exon
subclass of: SO_0000010

852236
type: Gene
SIO_000068: ncbigene

position:135998:1
position: 135998
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:136366:1
position: 136366
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:135998-136366:1:exon

YBL044W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBL044W
product: uncharacterized protein
transcript id: NM_001178284.1
SIO_010081: YBL044W
subclass of: SO_0000673
so part of: YBL044W
location: <135998..>136366
location: region:135998-136366:1
so has part: feature:135998-136366:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:135998-136366:1:exon

YBL044W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBL044W
note: hypothetical protein; YBL044W is not an essential protein
codon start: 1
product: uncharacterized protein
translation: MGEMLERQKKRLPSKAKYLKYTASITETGNHEADSSVIFRPHHSDVTCSNARRAESRTLPQICSCILLDHGRRTRPEVRTGMVSLHGSFKGFPCFGIRRGISHVLPGQKLRGSCDNWKKRQN
SIO_010081: YBL044W
subclass of: SO_0000673
so part of: YBL044W
location: 135998..136366
location: region:135998-136366:1
so has part: feature:135998-136366:1:exon

NP_009509.1
type: Protein
SIO_000068: ncbiprotein

S000000140
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:135998-136366:1:exon

YBL043W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ECM13
locus tag: YBL043W
so part of: sequence
location: <136688..>137461
location: region:136688-137461:1
so has part: feature:136688-137461:1:exon
subclass of: SO_0000010

852237
type: Gene
SIO_000068: ncbigene

position:136688:1
position: 136688
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:137461:1
position: 137461
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:136688-137461:1:exon

YBL043W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ECM13
locus tag: YBL043W
product: Ecm13p
transcript id: NM_001178283.1
SIO_010081: YBL043W
subclass of: SO_0000673
so part of: YBL043W
location: <136688..>137461
location: region:136688-137461:1
so has part: feature:136688-137461:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:136688-137461:1:exon

YBL043W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ECM13
locus tag: YBL043W
note: Non-essential hypothetical protein; induced by treatment with 8-methoxypsoralen and UVA irradiation; ECM13 has a paralog, YJR115W, that arose from the whole genome duplication
codon start: 1
product: Ecm13p
translation: MNSTTPSIQDQYILASKVRSKLAKCVSVTTKNKDYNLRVLVGHANLLDKITENVETHNAATNALAGDPFSKGPENLSIEHIELSNANASKNDVGKEENAEKTIESEDYCDFYSSDEDPDADTLSSTDSEDDDDYEDYDFEYDYSGGDYNKKIDMYFSFHTAPNYQYLTHTNSHSEQTDELAESTPRYNALPATASTTEEEQDTETLDAVSLHSSAPIFRVLSRRVNGQEDDSENESSSDVDDGSVPLTRFHSCPITA
SIO_010081: YBL043W
subclass of: SO_0000673
so part of: YBL043W
location: 136688..137461
location: region:136688-137461:1
so has part: feature:136688-137461:1:exon

NP_009510.1
type: Protein
SIO_000068: ncbiprotein

S000000139
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:136688-137461:1:exon

YBL042C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FUI1
locus tag: YBL042C
so part of: sequence
location: complement(<138341..>140260)
location: region:138341-140260:-1
so has part: feature:138341-140260:-1:exon
subclass of: SO_0000010

852238
type: Gene
SIO_000068: ncbigene

position:138341:-1
position: 138341
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:140260:-1
position: 140260
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:138341-140260:-1:exon

YBL042C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FUI1
locus tag: YBL042C
product: uridine permease
transcript id: NM_001178282.1
SIO_010081: YBL042C
subclass of: SO_0000673
so part of: YBL042C
location: complement(<138341..>140260)
location: region:138341-140260:-1
so has part: feature:138341-140260:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:138341-140260:-1:exon

YBL042C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FUI1
locus tag: YBL042C
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:16854981|PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0015213 uridine transmembrane transporter activity [PMID:16854981]
experiment: EXISTENCE:direct assay:GO:0015862 uridine transport [PMID:16854981]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0005886 plasma membrane [PMID:10827169]
experiment: EXISTENCE:mutant phenotype:GO:0015213 uridine transmembrane transporter activity [PMID:10827169]
experiment: EXISTENCE:mutant phenotype:GO:0015862 uridine transport [PMID:10827169|PMID:16854981]
experiment: EXISTENCE:mutant phenotype:GO:0055085 transmembrane transport [PMID:10827169]
note: High affinity uridine permease, localizes to the plasma membrane; also mediates low but significant transport of the cytotoxic nucleoside analog 5-fluorouridine; not involved in uracil transport; relative distribution to the vacuole increases upon DNA replication stress
codon start: 1
product: uridine permease
translation: MPVSDSGFDNSSKTMKDDTIPTEDYEEITKESEMGDATKITSKIDANVIEKKDTDSENNITIAQDDEKVSWLQRVVEFFEVKNDSTDLADHKPENPIRTFKDLQESLRSTYLYNTDLRPVEAKRRTWTWKQYIFFWISGSFNVNTWQISATGLQLGLNWWQTWICIWVGYTFVAFFLILGSKVGNNYHISFPISSRVSFGIYFSIWIVINRVVMACVWNSTLAYIGSQCVQLMLKAIFGTNLNTRIKDTIKNPNLTNFEFMCFMVFWVACLPFLWFPPDKLRHIFALKSAITPFAAFGFLIWTLCKAKGHLALGSLNDNGGAISKTVLAWSVIRAIMSALDNFSTLILNAPDFTRFGKTYKSSVYSQLIALPVCYAIISLIGILSVSAAYTLYGVNYWSPLDILNRYLDNYTSGNRAGVFLISFIFAFDQLGANLSGNSIPAGTDLTALLPKFINIRRGSYICALISLAICPWDLLSSSSKFTTALAAYAVFLSAIAGVISADYFIVRKGYVNIFHCYTDKPGSYYMYNKYGTNWRAVVAYIFGIAPNFAGFLGSVGVSVPIGAMKVYYLNYFVGYLLAALSYCILVYFYPIKGIPGDAKITDRKWLEEWVEVEEFGTEREAFEEYGGVSTGYEKIRYI
SIO_010081: YBL042C
subclass of: SO_0000673
so part of: YBL042C
location: complement(138341..140260)
location: region:138341-140260:-1
so has part: feature:138341-140260:-1:exon

NP_009511.1
type: Protein
SIO_000068: ncbiprotein

S000000138
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:138341-140260:-1:exon

YBL041W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PRS3
gene: PRE7
locus tag: YBL041W
gene synonym: PRS3
so part of: sequence
location: <141247..>141972
location: region:141247-141972:1
so has part: feature:141247-141972:1:exon
subclass of: SO_0000010

852239
type: Gene
SIO_000068: ncbigene

position:141247:1
position: 141247
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:141972:1
position: 141972
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:141247-141972:1:exon

YBL041W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PRS3
gene: PRE7
locus tag: YBL041W
gene synonym: PRS3
product: proteasome core particle subunit beta 6
transcript id: NM_001178281.1
SIO_010081: YBL041W
subclass of: SO_0000673
so part of: YBL041W
location: <141247..>141972
location: region:141247-141972:1
so has part: feature:141247-141972:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:141247-141972:1:exon

YBL041W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PRS3
gene: PRE7
locus tag: YBL041W
gene synonym: PRS3
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0010499 proteasomal ubiquitin-independent protein catabolic process [PMID:19162040]
experiment: EXISTENCE:direct assay:GO:0019774 proteasome core complex, beta-subunit complex [PMID:9087403]
experiment: EXISTENCE:direct assay:GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process [PMID:11545745|PMID:19029916]
note: Beta 6 subunit of the 20S proteasome
codon start: 1
product: proteasome core particle subunit beta 6
translation: MATIASEYSSEASNTPIEHQFNPYGDNGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKRFKNSVKWYHFDHNDKKLSINSAARNIQHLLYGKRFFPYYVHTIIAGLDEDGKGAVYSFDPVGSYEREQCRAGGAAASLIMPFLDNQVNFKNQYEPGTNGKVKKPLKYLSVEEVIKLVRDSFTSATERHIQVGDGLEILIVTKDGVRKEFYELKRD
SIO_010081: YBL041W
subclass of: SO_0000673
so part of: YBL041W
location: 141247..141972
location: region:141247-141972:1
so has part: feature:141247-141972:1:exon

NP_009512.1
type: Protein
SIO_000068: ncbiprotein

S000000137
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:141247-141972:1:exon

YBL040C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ERD2
locus tag: YBL040C
so part of: sequence
location: complement(<142112..>142868)
location: region:142112-142868:-1
so has part: feature:142112-142868:-1:exon
subclass of: SO_0000010

852240
type: Gene
SIO_000068: ncbigene

position:142112:-1
position: 142112
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:142868:-1
position: 142868
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:142112-142868:-1:exon

YBL040C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ERD2
locus tag: YBL040C
product: Erd2p
transcript id: NM_001178280.1
SIO_010081: YBL040C
subclass of: SO_0000673
so part of: YBL040C
location: complement(join(<142112..142749,142847..>142868))
location: region:142112-142868:-1
so has part: feature:142847-142868:-1:exon
so has part: feature:142112-142749:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:142847-142868:-1:exon

position:142847:-1
position: 142847
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:142112-142749:-1:exon

position:142749:-1
position: 142749
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YBL040C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ERD2
locus tag: YBL040C
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:2194670]
experiment: EXISTENCE:mutant phenotype:GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport [PMID:2194671|PMID:9405360]
experiment: EXISTENCE:mutant phenotype:GO:0045015 HDEL sequence binding [PMID:2194670]
note: HDEL receptor; an integral membrane protein that binds to the HDEL motif in proteins destined for retention in the endoplasmic reticulum; has a role in maintenance of normal levels of ER-resident proteins
codon start: 1
product: Erd2p
translation: MNPFRILGDLSHLTSILILIHNIKTTRYIEGISFKTQTLYALVFITRYLDLLTFHWVSLYNALMKIFFIVSTAYIVVLLQGSKRTNTIAYNEMLMHDTFKIQHLLIGSALMSVFFHHKFTFLELAWSFSVWLESVAILPQLYMLSKGGKTRSLTVHYIFAMGLYRALYIPNWIWRYSTEDKKLDKIAFFAGLLQTLLYSDFFYIYYTKVIRGKGFKLPK
SIO_010081: YBL040C
subclass of: SO_0000673
so part of: YBL040C
location: complement(join(142112..142749,142847..142868))
location: region:142112-142868:-1
so has part: feature:142847-142868:-1:exon
so has part: feature:142112-142749:-1:exon

NP_009513.1
type: Protein
SIO_000068: ncbiprotein

S000000136
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:142847-142868:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:142112-142749:-1:exon

YBL039W-B
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YBL039W-A
gene: MIN6
locus tag: YBL039W-B
gene synonym: YBL039W-A
so part of: sequence
location: <143393..>143572
location: region:143393-143572:1
so has part: feature:143393-143572:1:exon
subclass of: SO_0000010

1466441
type: Gene
SIO_000068: ncbigene

position:143393:1
position: 143393
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:143572:1
position: 143572
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:143393-143572:1:exon

YBL039W-B
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YBL039W-A
gene: MIN6
locus tag: YBL039W-B
gene synonym: YBL039W-A
product: Min6p
transcript id: NM_001184527.1
SIO_010081: YBL039W-B
subclass of: SO_0000673
so part of: YBL039W-B
location: <143393..>143572
location: region:143393-143572:1
so has part: feature:143393-143572:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:143393-143572:1:exon

YBL039W-B
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YBL039W-A
gene: MIN6
locus tag: YBL039W-B
gene synonym: YBL039W-A
experiment: EXISTENCE:direct assay:GO:0005777 peroxisome [PMID:26928762]
note: Mitochondrial hypothetical protein; mCherry fusion protein localizes to the vacuole
codon start: 1
product: Min6p
translation: MGFFNNNPVIEFFHRITRKPSTIAMWVFAGLICSSTFYLMFMSSPTIDFNSKSKKKNDK
SIO_010081: YBL039W-B
subclass of: SO_0000673
so part of: YBL039W-B
location: 143393..143572
location: region:143393-143572:1
so has part: feature:143393-143572:1:exon

NP_878045.1
type: Protein
SIO_000068: ncbiprotein

S000028517
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:143393-143572:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS206; Autonomously replicating sequence
so part of: sequence
location: 143658..143745
location: region:143658-143745:1
so has part: feature:143658-143745:1:region

S000178042
type: SGD
SIO_000068: sgd

position:143658:1
position: 143658
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:143745:1
position: 143745
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:143658-143745:1:region

YBL039C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: URA7
locus tag: YBL039C
so part of: sequence
location: complement(<143989..>145728)
location: region:143989-145728:-1
so has part: feature:143989-145728:-1:exon
subclass of: SO_0000010

852241
type: Gene
SIO_000068: ncbigene

position:143989:-1
position: 143989
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:145728:-1
position: 145728
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:143989-145728:-1:exon

YBL039C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: URA7
locus tag: YBL039C
product: CTP synthase URA7
transcript id: NM_001178279.1
SIO_010081: YBL039C
subclass of: SO_0000673
so part of: YBL039C
location: complement(<143989..>145728)
location: region:143989-145728:-1
so has part: feature:143989-145728:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:143989-145728:-1:exon

YBL039C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: URA7
locus tag: YBL039C
EC number: 6.3.4.2
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0003883 CTP synthase activity [PMID:8075080]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0006241 CTP biosynthetic process [PMID:8075080]
experiment: EXISTENCE:direct assay:GO:0097268 cytoophidium [PMID:20713603]
experiment: EXISTENCE:mutant phenotype:GO:0003883 CTP synthase activity [PMID:1753946]
experiment: EXISTENCE:mutant phenotype:GO:0008654 phospholipid biosynthetic process [PMID:9668079]
experiment: EXISTENCE:mutant phenotype:GO:0019856 pyrimidine nucleobase biosynthetic process [PMID:1753946]
note: Major CTP synthase isozyme (see also URA8); catalyzes ATP-dependent transfer of amide nitrogen from glutamine to UTP, forming CTP, final step in de novo biosynthesis of pyrimidines; involved in phospholipid biosynthesis; targeted to vacuole via AP-3 pathway; capable of forming cytoplasmic filaments termed cytoophidium, especially during conditions of glucose depletion; URA7 has paralog URA8 that arose from the whole genome duplication
codon start: 1
product: CTP synthase URA7
translation: MKYVVVSGGVISGIGKGVLASSTGMLMKTLGLKVTSIKIDPYMNIDAGTMSPLEHGECFVLDDGGETDLDLGNYERYLGVTLTKDHNITTGKIYSHVIAKERKGDYLGKTVQIVPHLTNAIQDWIERVAKIPVDDTGMEPDVCIIELGGTVGDIESAPFVEALRQFQFKVGKENFALIHVSLVPVIHGEQKTKPTQAAIKGLRSLGLVPDMIACRCSETLDKPTIDKIAMFCHVGPEQVVNVHDVNSTYHVPLLLLEQKMIDYLHARLKLDEISLTEEEKQRGLELLSKWKATTGNFDESMETVKIALVGKYTNLKDSYLSVIKALEHSSMKCRRKLDIKWVEATDLEPEAQESNKTKFHEAWNMVSTADGILIPGGFGVRGTEGMVLAARWARENHIPFLGVCLGLQIATIEFTRSVLGRKDSHSAEFYPDIDEKNHVVVFMPEIDKETMGGSMRLGLRPTFFQNETEWSQIKKLYGDVSEVHERHRHRYEINPKMVDELENNGLIFVGKDDTGKRCEILELKNHPYYIATQYHPEYTSKVLDPSKPFLGLVAASAGILQDVIEGKYDLEAGENKFNF
SIO_010081: YBL039C
subclass of: SO_0000673
so part of: YBL039C
location: complement(143989..145728)
location: region:143989-145728:-1
so has part: feature:143989-145728:-1:exon

NP_009514.1
type: Protein
SIO_000068: ncbiprotein

S000000135
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:143989-145728:-1:exon

YBL038W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RML16
alternative label: uL16m
gene: MRPL16
locus tag: YBL038W
gene synonym: RML16; uL16m
so part of: sequence
location: <146187..>146885
location: region:146187-146885:1
so has part: feature:146187-146885:1:exon
subclass of: SO_0000010

852242
type: Gene
SIO_000068: ncbigene

position:146187:1
position: 146187
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:146885:1
position: 146885
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:146187-146885:1:exon

YBL038W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RML16
alternative label: uL16m
gene: MRPL16
locus tag: YBL038W
gene synonym: RML16; uL16m
product: mitochondrial 54S ribosomal protein YmL47
transcript id: NM_001178278.1
SIO_010081: YBL038W
subclass of: SO_0000673
so part of: YBL038W
location: <146187..>146885
location: region:146187-146885:1
so has part: feature:146187-146885:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:146187-146885:1:exon

YBL038W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RML16
alternative label: uL16m
gene: MRPL16
locus tag: YBL038W
gene synonym: RML16; uL16m
experiment: EXISTENCE:direct assay:GO:0003735 structural constituent of ribosome [PMID:7478995|PMID:9151978]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005762 mitochondrial large ribosomal subunit [PMID:7478995|PMID:9151978]
experiment: EXISTENCE:mutant phenotype:GO:0032543 mitochondrial translation [PMID:7478995]
note: Mitochondrial ribosomal protein of the large subunit; homologous to bacterial L16 ribosomal protein; synthetic lethality with hac1 mutation suggests a possible role in synthesis of precursors for protein glycosylation
codon start: 1
product: mitochondrial 54S ribosomal protein YmL47
translation: MFPYLTRMNLSIKMGGLTLKESSPNAFLNNTTIARRFKHEYAPRFKIVQKKQKGRVPVRTGGSIKGSTLQFGKYGLRLKSEGIRISAQQLKEADNAIMRYVRPLNNGHLWRRLCTNVAVCIKGNETRMGKGKGGFDHWMVRVPTGKILFEINGDDLHEKVAREAFRKAGTKLPGVYEFVSLDSLVRVGLHSFKNPKDDPVKNFYDENAKKPSKKYLNILKSQEPQYKLFRGR
SIO_010081: YBL038W
subclass of: SO_0000673
so part of: YBL038W
location: 146187..146885
location: region:146187-146885:1
so has part: feature:146187-146885:1:exon

NP_009515.1
type: Protein
SIO_000068: ncbiprotein

S000000134
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:146187-146885:1:exon

YBL037W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: APL3
locus tag: YBL037W
so part of: sequence
location: <147209..>150286
location: region:147209-150286:1
so has part: feature:147209-150286:1:exon
subclass of: SO_0000010

852243
type: Gene
SIO_000068: ncbigene

position:147209:1
position: 147209
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:150286:1
position: 150286
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:147209-150286:1:exon

YBL037W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: APL3
locus tag: YBL037W
product: Apl3p
transcript id: NM_001178277.1
SIO_010081: YBL037W
subclass of: SO_0000673
so part of: YBL037W
location: <147209..>150286
location: region:147209-150286:1
so has part: feature:147209-150286:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:147209-150286:1:exon

YBL037W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: APL3
locus tag: YBL037W
experiment: EXISTENCE:curator inference:GO:0006886 intracellular protein transport [PMID:10564262]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:19458192|PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0030122 AP-2 adaptor complex [PMID:10564262]
note: Alpha-adaptin; large subunit of the clathrin associated protein complex (AP-2); involved in vesicle mediated transport
codon start: 1
product: Apl3p
translation: MDRKKTLINSSVSNNNSTIKGLQLFIADLRSAQQAQEQEKRIQSEIVKIKQHFDAAKKKQGNHDRLGGYQRKKYVAKLAYIYITSNTTKLNEILFGLEQTVELLKSSIFSEKFIGYMTLELLYERSEVVAKVNDEVNYQLMKDLSSSDDNFVMLALNFVGVVGELTNRLAYNDDITTGVFKILRSPTSSIYLKKKSALSFLALLKSNHSILTEDLQRKQLWIQRILSLLDDTENYRLTLATIPLIEFIAKYIDPSYCTRLLPQLTEILYNCVVVGTSRSSDNQFPLEYTFANMPNPWLITKVVSLLSILIASPTERDSGSLLQTNNIDNELLNKLRKCVSVAIELGTRQAQDPMERIVQNTVLFSLINFASKLDPSDEAISNSVTALCSLLTSKEINIRYLTLDSLVKLCSSSGKPAIDAVRYKNLDMIFHLLNTERDSSIVRKVVDLLYTFTDVENVKIIVDGLLQYILSPKNLAEPQIKSDIAVKIAILTEKYATDINWFVIISLQLLSLTSNTTINDDEIWQRLCQIVVNNPSLHRITCERLVDYLCKKQASEAIIKAAAFLLGEYSSLITDRISSANLFTLFAEKYFSAPNVAKAMILTTMIKLYKTSPEIGSNVIKFFQLELNSLDIELQTRSFEYLNIIQLAKVNGNTDILQILFEPMPPFNSKSNPLLKRLGSLPASAGSTTLINTPSEASSSTPDLLSKRANSSRSIMVPMPPPSRRNTIDDVNSKISSSEDFSGKDSYYSRQILAPNWREGFTRMISHKQGVLFTSSLMKVFYRITTPDAQQPYVFHISLAFINLTEWEITGLSTQIIPSKTQGNPEYLIMNINTPSTATIGPHKRAEQSYEVSIRKPFDVEDSPILAIHFKCGGSTNTINLKTAIGMTTTLISSDVNPSMHLNLAQFISRWKTLSDALGKEGEYQKSGIKLNKDFRKVETISLEDGLLLLTQTVKRLGFDIVDQTSVRSTLFVSGIIHTKSEGNFGCLMKIQYQVNGTVNVTCKTTTAGPLAKYIVECIKNVLTK
SIO_010081: YBL037W
subclass of: SO_0000673
so part of: YBL037W
location: 147209..150286
location: region:147209-150286:1
so has part: feature:147209-150286:1:exon

NP_009516.1
type: Protein
SIO_000068: ncbiprotein

S000000133
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:147209-150286:1:exon

YBL036C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBL036C
so part of: sequence
location: complement(<150447..>151220)
location: region:150447-151220:-1
so has part: feature:150447-151220:-1:exon
subclass of: SO_0000010

852244
type: Gene
SIO_000068: ncbigene

position:150447:-1
position: 150447
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:151220:-1
position: 151220
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:150447-151220:-1:exon

YBL036C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBL036C
product: uncharacterized protein
transcript id: NM_001178276.1
SIO_010081: YBL036C
subclass of: SO_0000673
so part of: YBL036C
location: complement(<150447..>151220)
location: region:150447-151220:-1
so has part: feature:150447-151220:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:150447-151220:-1:exon

YBL036C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBL036C
experiment: EXISTENCE:direct assay:GO:0030170 pyridoxal phosphate binding [PMID:12499548]
note: Putative non-specific single-domain racemase; based on structural similarity; binds pyridoxal 5'-phosphate; expression of GFP-fusion protein induced in response to the DNA-damaging agent MMS
codon start: 1
product: uncharacterized protein
translation: MSTGITYDEDRKTQLIAQYESVREVVNAEAKNVHVNENASKILLLVVSKLKPASDIQILYDHGVREFGENYVQELIEKAKLLPDDIKWHFIGGLQTNKCKDLAKVPNLYSVETIDSLKKAKKLNESRAKFQPDCNPILCNVQINTSHEDQKSGLNNEAEIFEVIDFFLSEECKYIKLNGLMTIGSWNVSHEDSKENRDFATLVEWKKKIDAKFGTSLKLSMGMSADFREAIRQGTAEVRIGTDIFGARPPKNEARII
SIO_010081: YBL036C
subclass of: SO_0000673
so part of: YBL036C
location: complement(150447..151220)
location: region:150447-151220:-1
so has part: feature:150447-151220:-1:exon

NP_009517.1
type: Protein
SIO_000068: ncbiprotein

S000000132
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:150447-151220:-1:exon

YBL035C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: POL12
locus tag: YBL035C
so part of: sequence
location: complement(<151493..>153610)
location: region:151493-153610:-1
so has part: feature:151493-153610:-1:exon
subclass of: SO_0000010

852245
type: Gene
SIO_000068: ncbigene

position:151493:-1
position: 151493
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:153610:-1
position: 153610
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:151493-153610:-1:exon

YBL035C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: POL12
locus tag: YBL035C
product: DNA-directed DNA polymerase alpha subunit POL12
transcript id: NM_001178275.1
SIO_010081: YBL035C
subclass of: SO_0000673
so part of: YBL035C
location: complement(<151493..>153610)
location: region:151493-153610:-1
so has part: feature:151493-153610:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:151493-153610:-1:exon

YBL035C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: POL12
locus tag: YBL035C
experiment: EXISTENCE:curator inference:GO:0006273 lagging strand elongation [PMID:3888995]
experiment: EXISTENCE:direct assay:GO:0003887 DNA-directed DNA polymerase activity [PMID:1704371|PMID:3888995]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:8289832|PMID:15282802]
experiment: EXISTENCE:direct assay:GO:0005635 nuclear envelope [PMID:15282802]
experiment: EXISTENCE:direct assay:GO:0005658 alpha DNA polymerase:primase complex [PMID:22593576|PMID:3888995]
experiment: EXISTENCE:genetic interaction:GO:0016233 telomere capping [PMID:15132993]
experiment: EXISTENCE:mutant phenotype:GO:0006270 DNA replication initiation [PMID:8289832]
experiment: EXISTENCE:mutant phenotype:GO:0016233 telomere capping [PMID:15132993]
experiment: EXISTENCE:physical interaction:GO:0016233 telomere capping [PMID:15132993]
note: B subunit of DNA polymerase alpha-primase complex; required for initiation of DNA replication during mitotic and premeiotic DNA synthesis; also functions in telomere capping and length regulation
codon start: 1
product: DNA-directed DNA polymerase alpha subunit POL12
translation: MSGSIDVITHFGPDADKPEIITALENLTKLHALSVEDLYIKWEQFSNQRRQTHTDLTSKNIDEFKQFLQLQMEKRANQISSSSKVNTSTKKPVIKKSLNSSPLFGLSIPKTPTLKKRKLHGPFSLSDSKQTYNVGSEAETNEKGNSSLKLEFTPGMAEDAVGDSAPLSHAKSSDAKTPGSSTFQTPTTNTPTTSRQNVPAGEILDSLNPENIEISSGNPNVGLLSTEEPSYNQVKVEPFYDAKKYKFRTMRQNLQEASDVLDDQIESFTKIIQNHYKLSPNDFADPTIQSQSEIYAVGRIVPDSPTYDKFLNPESLSLETSRMGGVGRRVRLDLSQVNELSFFLGQIVAFKGKNANGDYFTVNSILPLPYPNSPVSTSQELQEFQANLEGSSLKVIVTCGPYFANDNFSLELLQEFIDSINNEVKPHVLIMFGPFIDITHPLIASGKLPNFPQFKTQPKTLDELFLKLFTPILKTISPHIQTVLIPSTKDAISNHAAYPQASLIRKALQLPKRNFKCMANPSSFQINEIYFGCSNVDTFKDLKEVIKGGTTSSRYRLDRVSEHILQQRRYYPIFPGSIRTRIKPKDVSTKKETNDMESKEEKVYEHISGADLDVSYLGLTEFVGGFSPDIMIIPSELQHFARVVQNVVVINPGRFIRATGNRGSYAQITVQCPDLEDGKLTLVEGEEPVYLHNVWKRARVDLIAS
SIO_010081: YBL035C
subclass of: SO_0000673
so part of: YBL035C
location: complement(151493..153610)
location: region:151493-153610:-1
so has part: feature:151493-153610:-1:exon

NP_009518.1
type: Protein
SIO_000068: ncbiprotein

S000000131
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:151493-153610:-1:exon

YBL034C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: STU1
locus tag: YBL034C
so part of: sequence
location: complement(<153848..>158389)
location: region:153848-158389:-1
so has part: feature:153848-158389:-1:exon
subclass of: SO_0000010

852246
type: Gene
SIO_000068: ncbigene

position:153848:-1
position: 153848
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:158389:-1
position: 158389
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:153848-158389:-1:exon

YBL034C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: STU1
locus tag: YBL034C
product: Stu1p
transcript id: NM_001178274.1
SIO_010081: YBL034C
subclass of: SO_0000673
so part of: YBL034C
location: complement(<153848..>158389)
location: region:153848-158389:-1
so has part: feature:153848-158389:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:153848-158389:-1:exon

YBL034C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: STU1
locus tag: YBL034C
experiment: EXISTENCE:direct assay:GO:0000776 kinetochore [PMID:19952112]
experiment: EXISTENCE:direct assay:GO:0005827 polar microtubule [PMID:19952112]
experiment: EXISTENCE:direct assay:GO:0008017 microtubule binding [PMID:12058056]
experiment: EXISTENCE:direct assay:GO:0043515 kinetochore binding [PMID:19952112]
experiment: EXISTENCE:direct assay:GO:0048487 beta-tubulin binding [PMID:12058056]
experiment: EXISTENCE:direct assay:GO:0072686 mitotic spindle [PMID:19952112|PMID:7806575]
experiment: EXISTENCE:direct assay:GO:1990023 mitotic spindle midzone [PMID:19952112]
experiment: EXISTENCE:mutant phenotype:GO:0008017 microtubule binding [PMID:12058056]
experiment: EXISTENCE:mutant phenotype:GO:0008608 attachment of spindle microtubules to kinetochore [PMID:19952112]
experiment: EXISTENCE:mutant phenotype:GO:0048487 beta-tubulin binding [PMID:12058056]
experiment: EXISTENCE:mutant phenotype:GO:0090307 mitotic spindle assembly [PMID:7806575]
note: Microtubule plus-end-tracking non-motor protein; binds to MTs, stabilizing interpolar MT plus ends, facilitating polymerization of spindle MTs and producing an outward force on spindle poles; required for structural integrity of the mitotic spindle; binds detached kinetochores (KTs) and promotes capture; relocalizes to MTs and stabilizes the spindle once captured KTs reach a spindle pole; localizes to the spindle, spindles poles, and detached KTs; CLASP family member homologous to human CLASP1/2
codon start: 1
product: Stu1p
translation: MSSFNNETNNNSNTNTHPDDSFPLYTVFKDESVPIEEKMALLTRFKGHVKKELVNESSIQAYFAALLFISGHYAYRSYPRLIFLSHSSLCYLIKRVAMQSPVQFNDTLVEQLLNHLIFELPNEKKFWLASIKAIEAIYLVNPSKIQAILANFLRRPSENQNGDYLNRIKSTLLTIDELIQINEKNNSNHLQLLRFFMLSFTNLLNNNLNEHANDDNNNVIIELIFDIMYKYLKMDDENSQDLIDGFINDLEVEKFKQKFISLAKSQDQHGSQEDKSTLFDEEYEFQLLLAEAKLPQLSNNLSSKDPAMKKNYESLNQLQQDLENLLAPFQSVKETEQNWKLRQSNIIELDNIISGNIPKDNPEEFVTVIKEVQLIELISRATSSLRTTLSLTALLFLKRLIHILNDQLPLSILDQIFVIFKNLLSSTKKISSQTAFHCLITLIIDINHFHNKLFQLSFLLINEKTVTPRFCSAILLRSFLIKFNDSNLSLNNSNTTSPTSKLENNIIYIEEWLKKGISDSQTTVREAMRLTFWYFYKCYPTNAKRLLSSSFSPQLKKATELAIPAHLNINYQVSRVSSTASASSATSRLYSHSSNNSSRKTSLLEQKRNYPSYAQPTQSSSTSLLNAPAVTAGGSVIASKLSNKLKTNLRSTSEYSSKENEKRARHHDSMNSVSNSNTKDNNNVTKRKVSAPPSSTAATKVSENYTNFDDFPSNQIDLTDELSNSYSNPLIKKYMDKNDVSMSSSPISLKGSNKLGEYETLYKKFNDASFPAQIKDALQYLQKELLLTSQQSSSAPKFEFPMIMKKLRQIMIKSPNDFKPFLSIEKFTNGVPLNYLIELYSINSFDYAEILKNRMNPEKPYELTNLIITIADLFNFLNANNCPNDFKLYYMKYKTTFFNYNFKLLLEIFRNLNIKHDNTLRSGTNDLMPKISMILFQIYGKEFDYTCYFNLIFEIYKFDNNRFNKLLADFDIVSTKMKICHELEKKDANFKVEDIISRESSVSFTPIDNKKSEGDEESDDAVDENDVKKCMEMTMINPFKNLETDKTLELKNNVGKRTSSTDSVVIHDDNDKDKKLSEMTKIVSVYQLDQPNPAKEEDDIDMENSQKSDLNLSEIFQNSGENTERKLKDDNEPTVKFSTDPPKIINEPEKLIGNGNENEKPDLETMSPIKINGDENMGQKQRITVKRERDVALTEQDINSKKMKLVNNKKSEKMHLLIMDNFPRDSLTVYEISHLLMVDSNGNTLMDFDVYFNHMSKAINRIKSGSFTMKHINYLIEPLITCFQNQKMTDWLTNENGFDELLDVAIMLLKSTDDTPSIPSKISSKSIILVHCLLVWKKFLNTLSENADDDGVSVRMCFEEVWEQILLMLNKFSDYGNEIYKLAQEFRDSLMLSHFFKKHSATRILSMLVTEIQPDTAGVKETFLIETLWKMLQSPTICQQFKKSNISEIIQTMSYFIMGTDNTSWNFTSAVVLARCLRVLQTTPDYTEQETERLFDCLPKNVFKMIMFIASNE
SIO_010081: YBL034C
subclass of: SO_0000673
so part of: YBL034C
location: complement(153848..158389)
location: region:153848-158389:-1
so has part: feature:153848-158389:-1:exon

NP_009519.1
type: Protein
SIO_000068: ncbiprotein

S000000130
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:153848-158389:-1:exon

YBL033C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RIB1
locus tag: YBL033C
so part of: sequence
location: complement(<158656..>159693)
location: region:158656-159693:-1
so has part: feature:158656-159693:-1:exon
subclass of: SO_0000010

852247
type: Gene
SIO_000068: ncbigene

position:158656:-1
position: 158656
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:159693:-1
position: 159693
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:158656-159693:-1:exon

YBL033C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RIB1
locus tag: YBL033C
product: GTP cyclohydrolase II
transcript id: NM_001178273.1
SIO_010081: YBL033C
subclass of: SO_0000673
so part of: YBL033C
location: complement(<158656..>159693)
location: region:158656-159693:-1
so has part: feature:158656-159693:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:158656-159693:-1:exon

YBL033C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RIB1
locus tag: YBL033C
EC number: 3.5.4.25
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0009231 riboflavin biosynthetic process [PMID:4555411|PMID:5366000]
experiment: EXISTENCE:mutant phenotype:GO:0019238 cyclohydrolase activity [PMID:4555411]
note: GTP cyclohydrolase II; catalyzes the first step of the riboflavin biosynthesis pathway
codon start: 1
product: GTP cyclohydrolase II
translation: MTIDNYDNSKQDSSKYEVSGTGDGRNGDGGLPLVQCVARARIPTTQGPDIFLHLYSNNRDNKEHLAIVFGEDIRSRSLFRRRQCETQQDRMIRGAYIGKLYPGRTVADEDDRLGLALEFDDSTGELLASKATTWDAHNDTLVRIHSECYTGENAWSARCDCGEQFDRAGRLIACDHEPTSNIKGGNGHGVIVYLRQEGRGIGLGEKLKAYNLQDLGADTVQANLMLKHPVDARDFSLGKAILLDLGIGNVRLLTNNPEKIKQVDHAPYLKCVERVPMVPIHWTNSSEGIDSKEIEGYLRTKIERMGHLLTEPLKLHTNPQPTETSEAQNQNRMNSALSSTSTLAI
SIO_010081: YBL033C
subclass of: SO_0000673
so part of: YBL033C
location: complement(158656..159693)
location: region:158656-159693:-1
so has part: feature:158656-159693:-1:exon

NP_009520.1
type: Protein
SIO_000068: ncbiprotein

S000000129
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:158656-159693:-1:exon

YBL032W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: KHD1
gene: HEK2
locus tag: YBL032W
gene synonym: KHD1
so part of: sequence
location: <160184..>161329
location: region:160184-161329:1
so has part: feature:160184-161329:1:exon
subclass of: SO_0000010

852248
type: Gene
SIO_000068: ncbigene

position:160184:1
position: 160184
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:161329:1
position: 161329
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:160184-161329:1:exon

YBL032W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: KHD1
gene: HEK2
locus tag: YBL032W
gene synonym: KHD1
product: Hek2p
transcript id: NM_001178272.1
SIO_010081: YBL032W
subclass of: SO_0000673
so part of: YBL032W
location: <160184..>161329
location: region:160184-161329:1
so has part: feature:160184-161329:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:160184-161329:1:exon

YBL032W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: KHD1
gene: HEK2
locus tag: YBL032W
gene synonym: KHD1
experiment: EXISTENCE:direct assay:GO:0000781 chromosome, telomeric region [PMID:11739741]
experiment: EXISTENCE:direct assay:GO:0000932 P-body [PMID:20953064|PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:11867544|PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11867544]
experiment: EXISTENCE:direct assay:GO:0008298 intracellular mRNA localization [PMID:11867544]
experiment: EXISTENCE:genetic interaction:GO:0000723 telomere maintenance [PMID:11739741]
experiment: EXISTENCE:genetic interaction:GO:0048255 mRNA stabilization [PMID:20953064]
experiment: EXISTENCE:mutant phenotype:GO:0007004 telomere maintenance via telomerase [PMID:11739741]
experiment: EXISTENCE:mutant phenotype:GO:0008298 intracellular mRNA localization [PMID:11867544]
experiment: EXISTENCE:mutant phenotype:GO:0048255 mRNA stabilization [PMID:20953064]
note: RNA binding protein involved in asymmetric localization of ASH1 mRNA; represses translation of ASH1 mRNA, an effect reversed by Yck1p-dependent phosphoryation; regulates telomere position effect and length; similarity to hnRNP-K; increases mRNA stability by binding (CNN)n repeat elements
codon start: 1
product: Hek2p
translation: MSQFFEAATPVAIPTNNTNGGSSDAGSAATGGAPVVGTTAQPTINHRLLLSLKEAAKIIGTKGSTISRIRAANAVKIGISEKVPGCSDRILSCAGNVINVANAIGDIVDVLNKRNPENEDAAEGEAEEHYYFHFLNHILPAPSKDEIRDLQQLEDIGYVRLIVANSHISSIIGKAGATIKSLINKHGVKIVASKDFLPASDERIIEIQGFPGSITNVLIEISEIILSDVDVRFSTERSYFPHLKKSSGEPTSPSTSSNTRIELKIPELYVGAIIGRGMNRIKNLKTFTKTNIVVERKDDDDKDENFRKFIITSKFPKNVKLAESMLLKNLNTEIEKRENYKRKLEAAEGDATVVTERSDSASFLEEKEEPQENHDNKEEQS
SIO_010081: YBL032W
subclass of: SO_0000673
so part of: YBL032W
location: 160184..161329
location: region:160184-161329:1
so has part: feature:160184-161329:1:exon

NP_009521.1
type: Protein
SIO_000068: ncbiprotein

S000000128
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:160184-161329:1:exon

YBL031W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SHE1
locus tag: YBL031W
so part of: sequence
location: <161699..>162715
location: region:161699-162715:1
so has part: feature:161699-162715:1:exon
subclass of: SO_0000010

852249
type: Gene
SIO_000068: ncbigene

position:161699:1
position: 161699
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:162715:1
position: 162715
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:161699-162715:1:exon

YBL031W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SHE1
locus tag: YBL031W
product: She1p
transcript id: NM_001178271.1
SIO_010081: YBL031W
subclass of: SO_0000673
so part of: YBL031W
location: <161699..>162715
location: region:161699-162715:1
so has part: feature:161699-162715:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:161699-162715:1:exon

YBL031W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SHE1
locus tag: YBL031W
experiment: EXISTENCE:direct assay:GO:0005819 spindle [PMID:17634282]
experiment: EXISTENCE:direct assay:GO:0005880 nuclear microtubule [PMID:17634282]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:17634282]
experiment: EXISTENCE:direct assay:GO:0008017 microtubule binding [PMID:23142046]
experiment: EXISTENCE:direct assay:GO:0015630 microtubule cytoskeleton [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0000022 mitotic spindle elongation [PMID:18194531]
note: Mitotic spindle protein; interacts with components of the Dam1 (DASH) complex, its effector Sli15p, and microtubule-associated protein Bim1p; also localizes to nuclear microtubules and to the bud neck in a ring-shaped structure; inhibits dynein function
codon start: 1
product: She1p
translation: MNDKLQEEHNEKDTTSQINGFTPPHMSIDFHSNNNSNIIETIGVSKRLGNSVLSELDSRASSKFEFLKDQSEQQYNGDKNNEPKSGSYNINEFFQAKHDSQFGQMESLDTHYTLLHTPKRKSQHAIPQDRSDSMKRSRPSRSIPYTTPVVNDITRRIRRLKLRNSLVNGNDIVARARSMQANSNINSIKNTPLSKPKPFMHKPNFLMPTTNSLNKINSAHRNTSSSSTASSIPRSKVHRSISIRDLHAKTKPVERTPVAQGTNSQLKNSVSVFDRLYKQTTFSRSTSMNNLSSGTSAKSKEHTNVKTRLVKSKTSGSLSSNLKQSTATGTKSDRPIWR
SIO_010081: YBL031W
subclass of: SO_0000673
so part of: YBL031W
location: 161699..162715
location: region:161699-162715:1
so has part: feature:161699-162715:1:exon

NP_009522.1
type: Protein
SIO_000068: ncbiprotein

S000000127
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:161699-162715:1:exon

YBL030C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: AAC2
alternative label: ANC2
gene: PET9
locus tag: YBL030C
gene synonym: AAC2; ANC2
so part of: sequence
location: complement(<163041..>163997)
location: region:163041-163997:-1
so has part: feature:163041-163997:-1:exon
subclass of: SO_0000010

852250
type: Gene
SIO_000068: ncbigene

position:163041:-1
position: 163041
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:163997:-1
position: 163997
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:163041-163997:-1:exon

YBL030C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: AAC2
alternative label: ANC2
gene: PET9
locus tag: YBL030C
gene synonym: AAC2; ANC2
product: ADP/ATP carrier protein PET9
transcript id: NM_001178270.1
SIO_010081: YBL030C
subclass of: SO_0000673
so part of: YBL030C
location: complement(<163041..>163997)
location: region:163041-163997:-1
so has part: feature:163041-163997:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:163041-163997:-1:exon

YBL030C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: AAC2
alternative label: ANC2
gene: PET9
locus tag: YBL030C
gene synonym: AAC2; ANC2
experiment: EXISTENCE:direct assay:GO:0005471 ATP:ADP antiporter activity [PMID:8476415]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:24769239|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005743 mitochondrial inner membrane [PMID:795470]
experiment: EXISTENCE:direct assay:GO:0005778 peroxisomal membrane [PMID:35127709]
experiment: EXISTENCE:direct assay:GO:0015866 ADP transport [PMID:8476415]
experiment: EXISTENCE:direct assay:GO:0015867 ATP transport [PMID:8476415|PMID:35127709]
experiment: EXISTENCE:direct assay:GO:0042626 ATPase-coupled transmembrane transporter activity [PMID:35127709]
experiment: EXISTENCE:direct assay:GO:0055085 transmembrane transport [PMID:8476415]
experiment: EXISTENCE:genetic interaction:GO:0009061 anaerobic respiration [PMID:1915842]
experiment: EXISTENCE:mutant phenotype:GO:0006839 mitochondrial transport [PMID:2167309]
experiment: EXISTENCE:mutant phenotype:GO:0006915 apoptotic process [PMID:17822411]
experiment: EXISTENCE:mutant phenotype:GO:0009060 aerobic respiration [PMID:2167309]
experiment: EXISTENCE:mutant phenotype:GO:0015886 heme transport [PMID:18728780]
note: Major ADP/ATP carrier of the mitochondrial inner membrane; exchanges cytosolic ADP for mitochondrially synthesized ATP; also imports heme and ATP; also functions in peroxisomes; required for viability in many lab strains that carry a sal1 mutation; PET9 has a paralog, AAC3, that arose from the whole genome duplication; human homolog SLC25A4 implicated in progressive external ophthalmoplegia can complement yeast null mutant
codon start: 1
product: ADP/ATP carrier protein PET9
translation: MSSNAQVKTPLPPAPAPKKESNFLIDFLMGGVSAAVAKTAASPIERVKLLIQNQDEMLKQGTLDRKYAGILDCFKRTATQEGVISFWRGNTANVIRYFPTQALNFAFKDKIKAMFGFKKEEGYAKWFAGNLASGGAAGALSLLFVYSLDYARTRLAADSKSSKKGGARQFNGLIDVYKKTLKSDGVAGLYRGFLPSVVGIVVYRGLYFGMYDSLKPLLLTGSLEGSFLASFLLGWVVTTGASTCSYPLDTVRRRMMMTSGQAVKYDGAFDCLRKIVAAEGVGSLFKGCGANILRGVAGAGVISMYDQLQMILFGKKFK
SIO_010081: YBL030C
subclass of: SO_0000673
so part of: YBL030C
location: complement(163041..163997)
location: region:163041-163997:-1
so has part: feature:163041-163997:-1:exon

NP_009523.1
type: Protein
SIO_000068: ncbiprotein

S000000126
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:163041-163997:-1:exon

YBL029C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBL029C-A
so part of: sequence
location: complement(<164488..>164772)
location: region:164488-164772:-1
so has part: feature:164488-164772:-1:exon
subclass of: SO_0000010

852251
type: Gene
SIO_000068: ncbigene

position:164488:-1
position: 164488
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:164772:-1
position: 164772
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:164488-164772:-1:exon

YBL029C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBL029C-A
product: uncharacterized protein
transcript id: NM_001184457.1
SIO_010081: YBL029C-A
subclass of: SO_0000673
so part of: YBL029C-A
location: complement(<164488..>164772)
location: region:164488-164772:-1
so has part: feature:164488-164772:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:164488-164772:-1:exon

YBL029C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBL029C-A
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:16622836]
note: hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery; protein abundance increases in response to DNA replication stress; has potential orthologs in Saccharomyces species and in Yarrowia lipolytica
codon start: 1
product: uncharacterized protein
translation: MSFIPIVCGMKSFDSSYDTVPGHQNLYCPNCHNYSVGPIKRKEFFTIWFIPLVPVFWGKQLHCPICNWRQDFKNDEQLNKVIQEQQNLRQKQPN
SIO_010081: YBL029C-A
subclass of: SO_0000673
so part of: YBL029C-A
location: complement(164488..164772)
location: region:164488-164772:-1
so has part: feature:164488-164772:-1:exon

NP_076874.1
type: Protein
SIO_000068: ncbiprotein

S000007591
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:164488-164772:-1:exon

YBL029W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBL029W
so part of: sequence
location: <166134..>167264
location: region:166134-167264:1
so has part: feature:166134-167264:1:exon
subclass of: SO_0000010

852252
type: Gene
SIO_000068: ncbigene

position:166134:1
position: 166134
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:167264:1
position: 167264
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:166134-167264:1:exon

YBL029W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBL029W
product: uncharacterized protein
transcript id: NM_001178269.1
SIO_010081: YBL029W
subclass of: SO_0000673
so part of: YBL029W
location: <166134..>167264
location: region:166134-167264:1
so has part: feature:166134-167264:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:166134-167264:1:exon

YBL029W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBL029W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
note: Non-essential hypothetical protein
codon start: 1
product: uncharacterized protein
translation: MCANIPEFDSFYENENINYNLESFAPLNCDVNSPFLPINNNDINVNAYGDENLTYSNFLLSYNDKLATTTAKNNSINNSNSNNNSNNNKNNNNNHNNNNLLGNDISQMAFLLDYPSTLNEPQFAVNCKDIYRKDISTPSSLVSSLPPAKFSLSLSNSPSPPPPSSSSLKHGEAIISNTSESSDIFADPNSFEKDTMPLTQELTLENLNNQLNYPDFTINAIEQDPAPSSFSSSSSSSESTVSSSRKRKPCHDSYTHSSPSSSESKKISDSRLSAEGLAKVLNLESPEEALKRERFILGIFQNELNYPLGYKTWIRDTTKEYRTKLINQLHERVKVKYPEYNQSILETIIRRGTYYMMQSRLRRERRMKLKERKRTT
SIO_010081: YBL029W
subclass of: SO_0000673
so part of: YBL029W
location: 166134..167264
location: region:166134-167264:1
so has part: feature:166134-167264:1:exon

NP_009524.1
type: Protein
SIO_000068: ncbiprotein

S000000125
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:166134-167264:1:exon

YBL028C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBL028C
so part of: sequence
location: complement(<167518..>167838)
location: region:167518-167838:-1
so has part: feature:167518-167838:-1:exon
subclass of: SO_0000010

852253
type: Gene
SIO_000068: ncbigene

position:167518:-1
position: 167518
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:167838:-1
position: 167838
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:167518-167838:-1:exon

YBL028C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBL028C
product: uncharacterized protein
transcript id: NM_001178268.1
SIO_010081: YBL028C
subclass of: SO_0000673
so part of: YBL028C
location: complement(<167518..>167838)
location: region:167518-167838:-1
so has part: feature:167518-167838:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:167518-167838:-1:exon

YBL028C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBL028C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0030687 preribosome, large subunit precursor [PMID:17443350]
note: hypothetical protein that may interact with ribosomes; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus; predicted to be involved in ribosome biogenesis
codon start: 1
product: uncharacterized protein
translation: MAKSLRASSHLNAKSVKRRGVFQKAVDAREQRISDKLKEDLLKQKLEDLKKKEEQGIDMDVDEKKSNEEAPRKKISTSGWRDGRHHTYKKAKLMKQSKKKTSFTRF
SIO_010081: YBL028C
subclass of: SO_0000673
so part of: YBL028C
location: complement(167518..167838)
location: region:167518-167838:-1
so has part: feature:167518-167838:-1:exon

NP_009525.1
type: Protein
SIO_000068: ncbiprotein

S000000124
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:167518-167838:-1:exon

YBL027W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RPL19B
locus tag: YBL027W
so part of: sequence
location: <168423..>169376
location: region:168423-169376:1
so has part: feature:168423-169376:1:exon
subclass of: SO_0000010

852254
type: Gene
SIO_000068: ncbigene

position:168423:1
position: 168423
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:169376:1
position: 169376
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:168423-169376:1:exon

YBL027W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RPL19B
locus tag: YBL027W
product: ribosomal 60S subunit protein L19B
transcript id: NM_001178267.1
SIO_010081: YBL027W
subclass of: SO_0000673
so part of: YBL027W
location: join(<168423..168424,168809..>169376)
location: region:168423-169376:1
so has part: feature:168423-168424:1:exon
so has part: feature:168809-169376:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:168423-168424:1:exon

position:168424:1
position: 168424
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:168809-169376:1:exon

position:168809:1
position: 168809
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YBL027W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RPL19B
locus tag: YBL027W
experiment: EXISTENCE:curator inference:GO:0002181 cytoplasmic translation [PMID:11983894]
experiment: EXISTENCE:curator inference:GO:0003735 structural constituent of ribosome [PMID:11983894]
experiment: EXISTENCE:direct assay:GO:0022625 cytosolic large ribosomal subunit [PMID:11983894]
note: Ribosomal 60S subunit protein L19B; rpl19a and rpl19b single null mutations result in slow growth, while the double null mutation is lethal; homologous to mammalian ribosomal protein L19, no bacterial homolog; RPL19B has a paralog, RPL19A, that arose from the whole genome duplication
codon start: 1
product: ribosomal 60S subunit protein L19B
translation: MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
SIO_010081: YBL027W
subclass of: SO_0000673
so part of: YBL027W
location: join(168423..168424,168809..169376)
location: region:168423-169376:1
so has part: feature:168423-168424:1:exon
so has part: feature:168809-169376:1:exon

NP_009526.1
type: Protein
SIO_000068: ncbiprotein

S000000123
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:168423-168424:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:168809-169376:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS207; Autonomously Replicating Sequence
so part of: sequence
location: 170173..170279
location: region:170173-170279:1
so has part: feature:170173-170279:1:region

S000118345
type: SGD
SIO_000068: sgd

position:170173:1
position: 170173
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:170279:1
position: 170279
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:170173-170279:1:region

YBL026W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SMX5
alternative label: SNP3
gene: LSM2
locus tag: YBL026W
gene synonym: SMX5; SNP3
so part of: sequence
location: <170623..>171038
location: region:170623-171038:1
so has part: feature:170623-171038:1:exon
subclass of: SO_0000010

852255
type: Gene
SIO_000068: ncbigene

position:170623:1
position: 170623
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:171038:1
position: 171038
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:170623-171038:1:exon

YBL026W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SMX5
alternative label: SNP3
gene: LSM2
locus tag: YBL026W
gene synonym: SMX5; SNP3
product: Sm-like protein LSM2
transcript id: NM_001178266.1
SIO_010081: YBL026W
subclass of: SO_0000673
so part of: YBL026W
location: join(<170623..170676,170805..>171038)
location: region:170623-171038:1
so has part: feature:170623-170676:1:exon
so has part: feature:170805-171038:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:170623-170676:1:exon

position:170676:1
position: 170676
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:170805-171038:1:exon

position:170805:1
position: 170805
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YBL026W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SMX5
alternative label: SNP3
gene: LSM2
locus tag: YBL026W
gene synonym: SMX5; SNP3
experiment: EXISTENCE:direct assay:GO:0000398 mRNA splicing, via spliceosome [PMID:10377396]
experiment: EXISTENCE:direct assay:GO:0000932 P-body [PMID:18611963]
experiment: EXISTENCE:direct assay:GO:0003723 RNA binding [PMID:15075370]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005688 U6 snRNP [PMID:10369684|PMID:11720284]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:15075370]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0046540 U4/U6 x U5 tri-snRNP complex [PMID:10377396|PMID:10449419]
experiment: EXISTENCE:direct assay:GO:1990726 Lsm1-7-Pat1 complex [PMID:24139796]
experiment: EXISTENCE:mutant phenotype:GO:0000398 mRNA splicing, via spliceosome [PMID:10428970]
experiment: EXISTENCE:physical interaction:GO:0005732 sno(s)RNA-containing ribonucleoprotein complex [PMID:15075370]
note: Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress
codon start: 1
product: Sm-like protein LSM2
translation: MLFFSFFKTLVDQEVVVELKNDIEIKGTLQSVDQFLNLKLDNISCTDEKKYPHLGSVRNIFIRGSTVRYVYLNKNMVDTNLLQDATRREVMTERK
SIO_010081: YBL026W
subclass of: SO_0000673
so part of: YBL026W
location: join(170623..170676,170805..171038)
location: region:170623-171038:1
so has part: feature:170623-170676:1:exon
so has part: feature:170805-171038:1:exon

NP_009527.1
type: Protein
SIO_000068: ncbiprotein

S000000122
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:170623-170676:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:170805-171038:1:exon

YBL025W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RRN10
locus tag: YBL025W
so part of: sequence
location: <171481..>171918
location: region:171481-171918:1
so has part: feature:171481-171918:1:exon
subclass of: SO_0000010

852256
type: Gene
SIO_000068: ncbigene

position:171481:1
position: 171481
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:171918:1
position: 171918
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:171481-171918:1:exon

YBL025W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RRN10
locus tag: YBL025W
product: Rrn10p
transcript id: NM_001178265.1
SIO_010081: YBL025W
subclass of: SO_0000673
so part of: YBL025W
location: <171481..>171918
location: region:171481-171918:1
so has part: feature:171481-171918:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:171481-171918:1:exon

YBL025W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RRN10
locus tag: YBL025W
experiment: EXISTENCE:direct assay:GO:0000500 RNA polymerase I upstream activating factor complex [PMID:8846924]
experiment: EXISTENCE:direct assay:GO:0001165 RNA polymerase I cis-regulatory region sequence-specific DNA binding [PMID:18451108]
experiment: EXISTENCE:direct assay:GO:0001181 RNA polymerase I general transcription initiation factor activity [PMID:8846924]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:22362748]
experiment: EXISTENCE:direct assay:GO:0042790 nucleolar large rRNA transcription by RNA polymerase I [PMID:8846924]
experiment: EXISTENCE:mutant phenotype:GO:0042790 nucleolar large rRNA transcription by RNA polymerase I [PMID:8846924]
note: Protein involved in promoting high level transcription of rDNA; subunit of UAF (upstream activation factor) for RNA polymerase I
codon start: 1
product: Rrn10p
translation: MDRNVYEACSNIIKEFGTHVVSADEVLAEKIDNAVPIPFKTREEIDADVEKDRNEGVFEGNIIPDIDLRVVHYYATQLCLNKYPHLINAFDETSLITLGLLIEKWVKDYLTSIQTEQGRQSKVIGKGPCEFISKHIDYRHAPGNI
SIO_010081: YBL025W
subclass of: SO_0000673
so part of: YBL025W
location: 171481..171918
location: region:171481-171918:1
so has part: feature:171481-171918:1:exon

NP_009528.1
type: Protein
SIO_000068: ncbiprotein

S000000121
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:171481-171918:1:exon

YBL024W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: TRM4
gene: NCL1
locus tag: YBL024W
gene synonym: TRM4
so part of: sequence
location: <172534..>174588
location: region:172534-174588:1
so has part: feature:172534-174588:1:exon
subclass of: SO_0000010

852257
type: Gene
SIO_000068: ncbigene

position:172534:1
position: 172534
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:174588:1
position: 174588
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:172534-174588:1:exon

YBL024W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: TRM4
gene: NCL1
locus tag: YBL024W
gene synonym: TRM4
product: tRNA (cytosine-C5-)-methyltransferase
transcript id: NM_001178264.1
SIO_010081: YBL024W
subclass of: SO_0000673
so part of: YBL024W
location: <172534..>174588
location: region:172534-174588:1
so has part: feature:172534-174588:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:172534-174588:1:exon

YBL024W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: TRM4
gene: NCL1
locus tag: YBL024W
gene synonym: TRM4
EC number: 2.1.1.202
experiment: EXISTENCE:direct assay:GO:0000049 tRNA binding [PMID:17567576]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:9767141]
experiment: EXISTENCE:direct assay:GO:0016428 tRNA (cytosine-5-)-methyltransferase activity [PMID:10445884]
experiment: EXISTENCE:direct assay:GO:0030488 tRNA methylation [PMID:10445884]
experiment: EXISTENCE:mutant phenotype:GO:0002127 tRNA wobble base cytosine methylation [PMID:22760636]
experiment: EXISTENCE:mutant phenotype:GO:0006417 regulation of translation [PMID:31416893]
experiment: EXISTENCE:mutant phenotype:GO:0019222 regulation of metabolic process [PMID:31416893]
experiment: EXISTENCE:mutant phenotype:GO:0070301 cellular response to hydrogen peroxide [PMID:22760636]
note: S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase; methylates cytosine to m5C at several positions in tRNAs and intron-containing pre-tRNAs; increases proportion of tRNALeu(CAA) with m5C at wobble position in response to hydrogen peroxide, causing selective translation of mRNA from genes enriched in TTG codon; loss of NCL1 confers hypersensitivity to oxidative stress; similar to Nop2p and human proliferation associated nucleolar protein p120
codon start: 1
product: tRNA (cytosine-C5-)-methyltransferase
translation: MARRKNFKKGNKKTFGARDDSRAQKNWSELVKENEKWEKYYKTLALFPEDQWEEFKKTCQAPLPLTFRITGSRKHAGEVLNLFKERHLPNLTNVEFEGEKIKAPVELPWYPDHLAWQLDVPKTVIRKNEQFAKTQRFLVVENAVGNISRQEAVSMIPPIVLEVKPHHTVLDMCAAPGSKTAQLIEALHKDTDEPSGFVVANDADARRSHMLVHQLKRLNSANLMVVNHDAQFFPRIRLHGNSNNKNDVLKFDRILCDVPCSGDGTMRKNVNVWKDWNTQAGLGLHAVQLNILNRGLHLLKNNGRLVYSTCSLNPIENEAVVAEALRKWGDKIRLVNCDDKLPGLIRSKGVSKWPVYDRNLTEKTKGDEGTLDSFFSPSEEEASKFNLQNCMRVYPHQQNTGGFFITVFEKVEDSTEAATEKLSSETPALESEGPQTKKIKVEEVQKKERLPRDANEEPFVFVDPQHEALKVCWDFYGIDNIFDRNTCLVRNATGEPTRVVYTVCPALKDVIQANDDRLKIIYSGVKLFVSQRSDIECSWRIQSESLPIMKHHMKSNRIVEANLEMLKHLLIESFPNFDDIRSKNIDNDFVEKMTKLSSGCAFIDVSRNDPAKENLFLPVWKGNKCINLMVCKEDTHELLYRIFGIDANAKATPSAEEKEKEKETTESPAETTTGTSTEAPSAAN
SIO_010081: YBL024W
subclass of: SO_0000673
so part of: YBL024W
location: 172534..174588
location: region:172534-174588:1
so has part: feature:172534-174588:1:exon

NP_009529.1
type: Protein
SIO_000068: ncbiprotein

S000000120
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:172534-174588:1:exon

YBL023C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MCM2
locus tag: YBL023C
so part of: sequence
location: complement(<174920..>177526)
location: region:174920-177526:-1
so has part: feature:174920-177526:-1:exon
subclass of: SO_0000010

852258
type: Gene
SIO_000068: ncbigene

position:174920:-1
position: 174920
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:177526:-1
position: 177526
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:174920-177526:-1:exon

YBL023C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MCM2
locus tag: YBL023C
product: MCM DNA helicase complex subunit MCM2
transcript id: NM_001178263.1
SIO_010081: YBL023C
subclass of: SO_0000673
so part of: YBL023C
location: complement(<174920..>177526)
location: region:174920-177526:-1
so has part: feature:174920-177526:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:174920-177526:-1:exon

YBL023C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MCM2
locus tag: YBL023C
EC number: 3.6.4.12
experiment: EXISTENCE:direct assay:GO:0003682 chromatin binding [PMID:10783164]
experiment: EXISTENCE:direct assay:GO:0003688 DNA replication origin binding [PMID:11756674|PMID:16824194]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:10704410|PMID:22842922|PMID:8224843]
experiment: EXISTENCE:direct assay:GO:0005656 nuclear pre-replicative complex [PMID:16824194|PMID:9335335]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:10704410|PMID:22842922|PMID:8224843]
experiment: EXISTENCE:direct assay:GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication [PMID:16824194]
experiment: EXISTENCE:direct assay:GO:0017116 single-stranded DNA helicase activity [PMID:18657510]
experiment: EXISTENCE:direct assay:GO:0031261 DNA replication preinitiation complex [PMID:9554851]
experiment: EXISTENCE:direct assay:GO:0031298 replication fork protection complex [PMID:16531994]
experiment: EXISTENCE:direct assay:GO:0042555 MCM complex [PMID:12480933]
experiment: EXISTENCE:direct assay:GO:0071162 CMG complex [PMID:26524492]
experiment: EXISTENCE:direct assay:GO:1905775 negative regulation of DNA helicase activity [PMID:13679365]
experiment: EXISTENCE:mutant phenotype:GO:0000727 double-strand break repair via break-induced replication [PMID:20516198]
experiment: EXISTENCE:mutant phenotype:GO:0003697 single-stranded DNA binding [PMID:17895243]
experiment: EXISTENCE:mutant phenotype:GO:0006271 DNA strand elongation involved in DNA replication [PMID:10834843]
experiment: EXISTENCE:mutant phenotype:GO:0006974 cellular response to DNA damage stimulus [PMID:22564307]
experiment: EXISTENCE:mutant phenotype:GO:1902975 mitotic DNA replication initiation [PMID:9407029|PMID:8224843]
note: Protein involved in DNA replication; component of the Mcm2-7 hexameric helicase complex that binds chromatin as a part of the pre-replicative complex; relative distribution to the nucleus increases upon DNA replication stress
codon start: 1
product: MCM DNA helicase complex subunit MCM2
translation: MSDNRRRRREEDDSDSENELPPSSPQQHFRGGMNPVSSPIGSPDMINPEGDDNEVDDVPDIDEVEEQMNEVDLMDDNMYEDYAADHNRDRYDPDQVDDREQQELSLSERRRIDAQLNERDRLLRNVAYIDDEDEEQEGAAQLDEMGLPVQRRRRRRQYEDLENSDDDLLSDMDIDPLREELTLESLSNVKANSYSEWITQPNVSRTIARELKSFLLEYTDETGRSVYGARIRTLGEMNSESLEVNYRHLAESKAILALFLAKCPEEMLKIFDLVAMEATELHYPDYARIHSEIHVRISDFPTIYSLRELRESNLSSLVRVTGVVTRRTGVFPQLKYVKFNCLKCGSILGPFFQDSNEEIRISFCTNCKSKGPFRVNGEKTVYRNYQRVTLQEAPGTVPPGRLPRHREVILLADLVDVSKPGEEVEVTGIYKNNYDGNLNAKNGFPVFATIIEANSIKRREGNTANEGEEGLDVFSWTEEEEREFRKISRDRGIIDKIISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVGLTASVRKDPITKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVVDSHVRSHPENDEDREGEELKNNGESAIEQGEDEINEQLNARQRRLQRQRKKEEEISPIPQELLMKYIHYARTKIYPKLHQMDMDKVSRVYADLRRESISTGSFPITVRHLESILRIAESFAKMRLSEFVSSYDLDRAIKVVVDSFVDAQKVSVRRQLRRSFAIYTLGH
SIO_010081: YBL023C
subclass of: SO_0000673
so part of: YBL023C
location: complement(174920..177526)
location: region:174920-177526:-1
so has part: feature:174920-177526:-1:exon

NP_009530.1
type: Protein
SIO_000068: ncbiprotein

S000000119
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:174920-177526:-1:exon

YBL022C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PIM1
locus tag: YBL022C
so part of: sequence
location: complement(<177874..>181275)
location: region:177874-181275:-1
so has part: feature:177874-181275:-1:exon
subclass of: SO_0000010

852259
type: Gene
SIO_000068: ncbigene

position:177874:-1
position: 177874
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:181275:-1
position: 181275
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:177874-181275:-1:exon

YBL022C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PIM1
locus tag: YBL022C
product: ATP-dependent Lon protease PIM1
transcript id: NM_001178262.1
SIO_010081: YBL022C
subclass of: SO_0000673
so part of: YBL022C
location: complement(<177874..>181275)
location: region:177874-181275:-1
so has part: feature:177874-181275:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:177874-181275:-1:exon

YBL022C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PIM1
locus tag: YBL022C
EC number: 3.4.21.53
experiment: EXISTENCE:direct assay:GO:0000262 mitochondrial chromosome [PMID:31532710]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:genetic interaction:GO:0006515 protein quality control for misfolded or incompletely synthesized proteins [PMID:7957078]
experiment: EXISTENCE:genetic interaction:GO:0051131 chaperone-mediated protein complex assembly [PMID:8810243]
experiment: EXISTENCE:mutant phenotype:GO:0004176 ATP-dependent peptidase activity [PMID:8146662|PMID:8276800]
experiment: EXISTENCE:mutant phenotype:GO:0005759 mitochondrial matrix [PMID:8146662|PMID:8276800]
experiment: EXISTENCE:mutant phenotype:GO:0006515 protein quality control for misfolded or incompletely synthesized proteins [PMID:16336126|PMID:7957078]
experiment: EXISTENCE:mutant phenotype:GO:1901858 regulation of mitochondrial DNA metabolic process [PMID:31532710]
note: ATP-dependent Lon protease; involved in degradation of misfolded mitochondrial proteins; required for mitochondrial maintenance and biogenesis; regulates mitochondrial DNA copy number with Mrx6p; subunit of a complex containing Mrx6p, Pet20p, and Mam33p that may regulate mtDNA replication; protease-independent, chaperone-like function in mitochondrial membrane complex assembly; localizes to the mitochondrial matrix
codon start: 1
product: ATP-dependent Lon protease PIM1
translation: MLRTRTTKTLSTVARTTRAIQYYRSIAKTAAVSQRRFASTLTVRDVENIKPSHIIKSPTWQEFQHQLKDPRYMEHFAQLDAQFARHFMATNSGKSILAKDDSTSQKKDEDVKIVPDEKDTDNDVEPTRDDEIVNKDQEGEASKNSRSSASGGGQSSSSRSDSGDGSSKQKPPKDVPEVYPQMLALPIARRPLFPGFYKAVVISDERVMKAIKEMLDRQQPYIGAFMLKNSEEDTDVITDKNDVYDVGVLAQITSAFPSKDEKTGTETMTALLYPHRRIKIDELFPPNEEKEKSKEQAKDTDTETTVVEDANNPEDQESTSPATPKLEDIVVERIPDSELQHHKRVEATEEESEELDDIQEGEDINPTEFLKNYNVSLVNVLNLEDEPFDRKSPVINALTSEILKVFKEISQLNTMFREQIATFSASIQSATTNIFEEPARLADFAAAVSAGEEDELQDILSSLNIEHRLEKSLLVLKKELMNAELQNKISKDVETKIQKRQREYYLMEQLKGIKRELGIDDGRDKLIDTYKERIKSLKLPDSVQKIFDDEITKLSTLETSMSEFGVIRNYLDWLTSIPWGKHSKEQYSIPRAKKILDEDHYGMVDVKDRILEFIAVGKLLGKVDGKIICFVGPPGVGKTSIGKSIARALNRKFFRFSVGGMTDVAEIKGHRRTYIGALPGRVVQALKKCQTQNPLILIDEIDKIGHGGIHGDPSAALLEVLDPEQNNSFLDNYLDIPIDLSKVLFVCTANSLETIPRPLLDRMEVIELTGYVAEDKVKIAEQYLVPSAKKSAGLENSHVDMTEDAITALMKYYCRESGVRNLKKHIEKIYRKAALQVVKKLSIEDSPTSSADSKPKESVSSEEKAENNAKSSSEKTKDNNSEKTSDDIEALKTSEKINVSISQKNLKDYVGPPVYTTDRLYETTPPGVVMGLAWTNMGGCSLYVESVLEQPLHNCKHPTFERTGQLGDVMKESSRLAYSFAKMYLAQKFPENRFFEKASIHLHCPEGATPKDGPSAGVTMATSFLSLALNKSIDPTVAMTGELTLTGKVLRIGGLREKAVAAKRSGAKTIIFPKDNLNDWEELPDNVKEGLEPLAADWYNDIFQKLFKDVNTKEGNSVWKAEFEILDAKKEKD
SIO_010081: YBL022C
subclass of: SO_0000673
so part of: YBL022C
location: complement(177874..181275)
location: region:177874-181275:-1
so has part: feature:177874-181275:-1:exon

NP_009531.1
type: Protein
SIO_000068: ncbiprotein

S000000118
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:177874-181275:-1:exon

YBL021C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HAP3
locus tag: YBL021C
so part of: sequence
location: complement(<181660..>182094)
location: region:181660-182094:-1
so has part: feature:181660-182094:-1:exon
subclass of: SO_0000010

852260
type: Gene
SIO_000068: ncbigene

position:181660:-1
position: 181660
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:182094:-1
position: 182094
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:181660-182094:-1:exon

YBL021C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HAP3
locus tag: YBL021C
product: Hap3p
transcript id: NM_001178261.1
SIO_010081: YBL021C
subclass of: SO_0000673
so part of: YBL021C
location: complement(<181660..>182094)
location: region:181660-182094:-1
so has part: feature:181660-182094:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:181660-182094:-1:exon

YBL021C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: HAP3
locus tag: YBL021C
experiment: EXISTENCE:direct assay:GO:0000436 carbon catabolite activation of transcription from RNA polymerase II promoter [PMID:2832951]
experiment: EXISTENCE:direct assay:GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding [PMID:7828851]
experiment: EXISTENCE:direct assay:GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific [PMID:2832951]
experiment: EXISTENCE:direct assay:GO:0016602 CCAAT-binding factor complex [PMID:2832951]
experiment: EXISTENCE:mutant phenotype:GO:0043457 regulation of cellular respiration [PMID:2182199]
experiment: EXISTENCE:physical interaction:GO:0016602 CCAAT-binding factor complex [PMID:2832951]
note: Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex; complex is heme-activated and glucose-repressed; complex is a transcriptional activator and global regulator of respiratory gene expression; contains sequences contributing to both complex assembly and DNA binding
codon start: 1
product: Hap3p
translation: MNTNESEHVSTSPEDTQENGGNASSSGSLQQISTLREQDRWLPINNVARLMKNTLPPSAKVSKDAKECMQECVSELISFVTSEASDRCAADKRKTINGEDILISLHALGFENYAEVLKIYLAKYRQQQALKNQLMYEQDDEEVP
SIO_010081: YBL021C
subclass of: SO_0000673
so part of: YBL021C
location: complement(181660..182094)
location: region:181660-182094:-1
so has part: feature:181660-182094:-1:exon

NP_009532.1
type: Protein
SIO_000068: ncbiprotein

S000000117
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:181660-182094:-1:exon

YBL020W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RFT1
locus tag: YBL020W
so part of: sequence
location: <182401..>184125
location: region:182401-184125:1
so has part: feature:182401-184125:1:exon
subclass of: SO_0000010

852261
type: Gene
SIO_000068: ncbigene

position:182401:1
position: 182401
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:184125:1
position: 184125
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:182401-184125:1:exon

YBL020W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RFT1
locus tag: YBL020W
product: glycolipid translocation protein
transcript id: NM_001178260.1
SIO_010081: YBL020W
subclass of: SO_0000673
so part of: YBL020W
location: <182401..>184125
location: region:182401-184125:1
so has part: feature:182401-184125:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:182401-184125:1:exon

YBL020W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RFT1
locus tag: YBL020W
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0005789 endoplasmic reticulum membrane [PMID:11807558]
experiment: EXISTENCE:genetic interaction:GO:0034203 glycolipid translocation [PMID:11807558]
experiment: EXISTENCE:mutant phenotype:GO:0005789 endoplasmic reticulum membrane [PMID:11807558]
experiment: EXISTENCE:mutant phenotype:GO:0034203 glycolipid translocation [PMID:11807558]
note: Membrane protein required for translocation of Man5GlcNac2-PP-Dol; required for translocation of Man5GlcNac2-PP-Dol from the cytoplasmic side to the lumenal side of the ER membrane but is not the flippase; mutation is suppressed by expression of human p53 protein; essential gene
codon start: 1
product: glycolipid translocation protein
translation: MAKKNSQLPSTSEQILERSTTGATFLMMGQLFTKLVTFILNNLLIRFLSPRIFGITAFLEFIQGTVLFFSRDAIRLSTLRISDSGNGIIDDDDEEEYQETHYKSKVLQTAVNFAYIPFWIGFPLSIGLIAWQYRNINAYFITLPFFRWSIFLIWLSIIVELLSEPFFIVNQFMLNYAARSRFESIAVTTGCIVNFIVVYAVQQSRYPMGVVTSDIDKEGIAILAFALGKLAHSITLLACYYWDYLKNFKPKKLFSTRLTKIKTRENNELKKGYPKSTSYFFQNDILQHFKKVYFQLCFKHLLTEGDKLIINSLCTVEEQGIYALLSNYGSLLTRLLFAPIEESLRLFLARLLSSHNPKNLKLSIEVLVNLTRFYIYLSLMIIVFGPANSSFLLQFLIGSKWSTTSVLDTIRVYCFYIPFLSLNGIFEAFFQSVATGDQILKHSYFMMAFSGIFLLNSWLLIEKLKLSIEGLILSNIINMVLRILYCGVFLNKFHRELFTDSSFFFNFKDFKTVIIAGSTICLLDWWFIGYVKNLQQFVVNVLFAMGLLALILVKERQTIQSFINKRAVSNSKDV
SIO_010081: YBL020W
subclass of: SO_0000673
so part of: YBL020W
location: 182401..184125
location: region:182401-184125:1
so has part: feature:182401-184125:1:exon

NP_009533.1
type: Protein
SIO_000068: ncbiprotein

S000000116
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:182401-184125:1:exon

YBL019W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ETH1
gene: APN2
locus tag: YBL019W
gene synonym: ETH1
so part of: sequence
location: <184353..>185915
location: region:184353-185915:1
so has part: feature:184353-185915:1:exon
subclass of: SO_0000010

852262
type: Gene
SIO_000068: ncbigene

position:184353:1
position: 184353
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:185915:1
position: 185915
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:184353-185915:1:exon

YBL019W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ETH1
gene: APN2
locus tag: YBL019W
gene synonym: ETH1
product: DNA-(apurinic or apyrimidinic site) lyase APN2
transcript id: NM_001178259.1
SIO_010081: YBL019W
subclass of: SO_0000673
so part of: YBL019W
location: <184353..>185915
location: region:184353-185915:1
so has part: feature:184353-185915:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:184353-185915:1:exon

YBL019W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ETH1
gene: APN2
locus tag: YBL019W
gene synonym: ETH1
EC number: 3.1.11.2
experiment: EXISTENCE:curator inference:GO:0005634 nucleus [PMID:10806210]
experiment: EXISTENCE:direct assay:GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity [PMID:10806210]
experiment: EXISTENCE:direct assay:GO:0008081 phosphoric diester hydrolase activity [PMID:11238902]
experiment: EXISTENCE:direct assay:GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity [PMID:11238902]
experiment: EXISTENCE:direct assay:GO:0008408 3'-5' exonuclease activity [PMID:30778235]
experiment: EXISTENCE:genetic interaction:GO:0006284 base-excision repair [PMID:9765213]
note: Class II abasic (AP) endonuclease involved in repair of DNA damage; also possesses 3'-diesterase and PCNA-stiimulated 3' to 5' exonuclease activities; resolves blocked 3' ends that result from removal of misincorporated nucleotides; frays and cleaves 3' DNA termini facilitating 3' DNA-end healing via endonucleolytic cleavage; homolog of human APEX2 and E. coli exoIII
codon start: 1
product: DNA-(apurinic or apyrimidinic site) lyase APN2
translation: MSSSENTLLDGKSENTIRFLTFNVNGIRTFFHYQPFSQMNQSLRSVFDFFRADIITFQELKTEKLSISKWGRVDGFYSFISIPQTRKGYSGVGCWIRIPEKNHPLYHALQVVKAEEGITGYLTIKNGKHSAISYRNDVNQGIGGYDSLDPDLDEKSALELDSEGRCVMVELACGIVIISVYCPANSNSSEEGEMFRLRFLKVLLRRVRNLDKIGKKIVLMGDVNVCRDLIDSADTLEQFSIPITDPMGGTKLEAQYRDKAIQFIINPDTPHRRIFNQILADSLLPDASKRGILIDTTRLIQTRNRLKMYTVWNMLKNLRPSNYGSRIDFILVSLKLERCIKAADILPDILGSDHCPVYSDLDILDDRIEPGTTQVPIPKFEARYKYNLRNHNVLEMFAKKDTNKESNKQKYCVSKVMNTKKNSNIKNKSLDSFFQKVNGEKDDRIKESSEIPQQAKKRISTPKLNFKDVFGKPPLCRHGEESMLKTSKTSANPGRKFWICKRSRGDSNNTESSCGFFQWV
SIO_010081: YBL019W
subclass of: SO_0000673
so part of: YBL019W
location: 184353..185915
location: region:184353-185915:1
so has part: feature:184353-185915:1:exon

NP_009534.1
type: Protein
SIO_000068: ncbiprotein

S000000115
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:184353-185915:1:exon

YBL018C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: POP8
locus tag: YBL018C
so part of: sequence
location: complement(<185998..>186474)
location: region:185998-186474:-1
so has part: feature:185998-186474:-1:exon
subclass of: SO_0000010

852263
type: Gene
SIO_000068: ncbigene

position:185998:-1
position: 185998
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:186474:-1
position: 186474
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:185998-186474:-1:exon

YBL018C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: POP8
locus tag: YBL018C
product: ribonuclease P
transcript id: NM_001178258.1
SIO_010081: YBL018C
subclass of: SO_0000673
so part of: YBL018C
location: complement(join(<185998..186352,186428..>186474))
location: region:185998-186474:-1
so has part: feature:186428-186474:-1:exon
so has part: feature:185998-186352:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:186428-186474:-1:exon

position:186428:-1
position: 186428
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:185998-186352:-1:exon

position:186352:-1
position: 186352
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YBL018C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: POP8
locus tag: YBL018C
EC number: 3.1.26.5
experiment: EXISTENCE:direct assay:GO:0000171 ribonuclease MRP activity [PMID:9620854]
experiment: EXISTENCE:direct assay:GO:0000172 ribonuclease MRP complex [PMID:9620854]
experiment: EXISTENCE:direct assay:GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay [PMID:14729943]
experiment: EXISTENCE:direct assay:GO:0004526 ribonuclease P activity [PMID:9620854]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0005655 nucleolar ribonuclease P complex [PMID:9620854]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0034965 intronic box C/D RNA processing [PMID:18713869]
experiment: EXISTENCE:mutant phenotype:GO:0004526 ribonuclease P activity [PMID:9620854]
experiment: EXISTENCE:mutant phenotype:GO:0008033 tRNA processing [PMID:9620854]
experiment: EXISTENCE:physical interaction:GO:0000172 ribonuclease MRP complex [PMID:17881380]
note: Subunit of both RNase MRP and nuclear RNase P; RNase MRP cleaves pre-rRNA, while nuclear RNase P cleaves tRNA precursors to generate mature 5' ends and facilitates turnover of nuclear RNAs; relocalizes to the cytosol in response to hypoxia
codon start: 1
product: ribonuclease P
translation: MGKKTFREWQYFKLSITSFDQDVDDAHAIDQMTWRQWLNNALKRSYGIFGEGVEYSFLHVDDKLAYIRVNHADKDTFSSSISTYISTDELVGSPLTVSILQESSSLRLLEVTDDDRLWLKKVMEEEEQDCKCI
SIO_010081: YBL018C
subclass of: SO_0000673
so part of: YBL018C
location: complement(join(185998..186352,186428..186474))
location: region:185998-186474:-1
so has part: feature:186428-186474:-1:exon
so has part: feature:185998-186352:-1:exon

NP_009535.1
type: Protein
SIO_000068: ncbiprotein

S000000114
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:186428-186474:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:185998-186352:-1:exon

YBL017C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: VPS10
alternative label: VPT1
gene: PEP1
locus tag: YBL017C
gene synonym: VPS10; VPT1
so part of: sequence
location: complement(<186844..>191583)
location: region:186844-191583:-1
so has part: feature:186844-191583:-1:exon
subclass of: SO_0000010

852264
type: Gene
SIO_000068: ncbigene

position:186844:-1
position: 186844
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:191583:-1
position: 191583
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:186844-191583:-1:exon

YBL017C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: VPS10
alternative label: VPT1
gene: PEP1
locus tag: YBL017C
gene synonym: VPS10; VPT1
product: type I sorting receptor
transcript id: NM_001178257.1
SIO_010081: YBL017C
subclass of: SO_0000673
so part of: YBL017C
location: complement(<186844..>191583)
location: region:186844-191583:-1
so has part: feature:186844-191583:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:186844-191583:-1:exon

YBL017C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: VPS10
alternative label: VPT1
gene: PEP1
locus tag: YBL017C
gene synonym: VPS10; VPT1
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005794 Golgi apparatus [PMID:20936498]
experiment: EXISTENCE:mutant phenotype:GO:0000423 mitophagy [PMID:31332264]
experiment: EXISTENCE:mutant phenotype:GO:0000425 pexophagy [PMID:31332264]
experiment: EXISTENCE:mutant phenotype:GO:0005048 signal sequence binding [PMID:8187177]
experiment: EXISTENCE:mutant phenotype:GO:0006623 protein targeting to vacuole [PMID:8187177]
experiment: EXISTENCE:mutant phenotype:GO:0007034 vacuolar transport [PMID:8187177]
note: Type I transmembrane sorting receptor for multiple vacuolar hydrolases; plays role in post-ER quality control in the Golgi, involved in protein targeting from the endoplasmic reticulum to the vacuole for degradation; cycles between late-Golgi and prevacuolar endosome-like compartments; targeted to vacuole via AP-3 pathway
codon start: 1
product: type I sorting receptor
translation: MILLHFVYSLWALLLIPLTNAEEFTPKVTKTIAQDSFDILSFDDSNTLIRKQDTSVTISFDDGETWEKVEGIEGEITWIYIDPFNRHDRAVATAMNGSYLYITNDQGKSWERITLPDSGESISPRECYIETHPLNKNYFLAKCNYCEKTEVNNDNEENSGDEEGQFEIFNITRCTDKVFASNDGGKSFSEIKSSLERNENSPISISDCGFAKTSKDSDLESSDTSIICLFQNMQLIMDEFSSPYTESKLVLTTDWGKSLKEFDQFKDKVVNGYRILKSHMVVLTQGDRYNDMSSMDVWVSNDLSNFKMAYMPTQLRHSMQGEIYEDAMGRIILPMSRERSDQEEDKGIVSEILISDSQGLKFSPIPWTANEVFGYINFYQPTYLKGTMIASLYPLSRRRNRKGKAKGVKSKGVTKISVDNGLTWTMLKVVDPDNADSFDCDITDFENCSLQNMFYTREGSTPTAGILMTTGIVGDGSVFDWGDQRTFISRDGGLTWKLAFDFPCLYAVGDYGNVIVAIPYNADEDDDPQSEFYYSLDQGKTWTEYQLETTIYPNEVMNTTPDGSGAKFILNGFTLAHMDGTTNFIYAIDFSTAFNDKTCEENDFEDWNLAEGKCVNGVKYKIRRRKQDAQCLVKKVFEDLQLFETACDKCTEADYECAFEFVRDATGKCVPDYNLIVLSDVCDKTKKKTVPVKPLQLVKGDKCKKPMTVKSVDISCEGVPKKGTNDKEIVVTENKFDFKIQFYQYFDTVTDESLLMINSRGEAYISHDGGQTIKRFDSNGETIIEVVFNPYYNSSAYLFGSKGSIFSTHDRGYSFMTAKLPEARQLGMPLDFNAKAQDTFIYYGGKNCESILSPECHAVAYLTNDGGETFTEMLDNAIHCEFAGSLFKYPSNEDMVMCQVKEKSSQTRSLVSSTDFFQDDKNTVFENIIGYLSTGGYIIVAVPHENNELRAYVTIDGTEFAEAKFPYDEDVGKQEAFTILESEKGSIFLHLATNLVPGRDFGNLLKSNSNGTSFVTLEHAVNRNTFGYVDFEKIQGLEGIILTNIVSNSDKVAENKEDKQLKTKITFNEGSDWNFLKPPKRDSEGKKFSCSSKSLDECSLHLHGYTERKDIRDTYSSGSALGMMFGVGNVGPNLLPYKECSTFFTTDGGETWAEVKKTPHQWEYGDHGGILVLVPENSETDSISYSTDFGKTWKDYKFCADKVLVKDITTVPRDSALRFLLFGEAADIGGSSFRTYTIDFRNIFERQCDFDITGKESADYKYSPLGSKSNCLFGHQTEFLRKTDENCFIGNIPLSEFSRNIKNCSCTRQDFECDYNFYKANDGTCKLVKGLSPANAADVCKKEPDLIEYFESSGYRKIPLSTCEGGLKLDAPSSPHACPGKEKEFKEKYSVSAGPFAFIFISILLIIFFAAWFVYDRGIRRNGGFARFGEIRLGDDGLIENNNTDRVVNNIVKSGFYVFSNIGSLLQHTKTNIAHAISKIRGRFGNRTGPSYSSLIHDQFLDEADDLLAGHDEDANDLSSFMDQGSNFEIEEDDVPTLEEEHTSYTDQPTTTDVPDTLPEGNEENIDRPDSTAPSNENQ
SIO_010081: YBL017C
subclass of: SO_0000673
so part of: YBL017C
location: complement(186844..191583)
location: region:186844-191583:-1
so has part: feature:186844-191583:-1:exon

NP_009536.1
type: Protein
SIO_000068: ncbiprotein

S000000113
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:186844-191583:-1:exon

YBL016W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: DAC2
gene: FUS3
locus tag: YBL016W
gene synonym: DAC2
so part of: sequence
location: <192451..>193512
location: region:192451-193512:1
so has part: feature:192451-193512:1:exon
subclass of: SO_0000010

852265
type: Gene
SIO_000068: ncbigene

position:192451:1
position: 192451
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:193512:1
position: 193512
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:192451-193512:1:exon

YBL016W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: DAC2
gene: FUS3
locus tag: YBL016W
gene synonym: DAC2
product: mitogen-activated serine/threonine-protein kinase FUS3
transcript id: NM_001178256.1
SIO_010081: YBL016W
subclass of: SO_0000673
so part of: YBL016W
location: <192451..>193512
location: region:192451-193512:1
so has part: feature:192451-193512:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:192451-193512:1:exon

YBL016W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: DAC2
gene: FUS3
locus tag: YBL016W
gene synonym: DAC2
EC number: 2.7.11.24
experiment: EXISTENCE:direct assay:GO:0000750 pheromone-dependent signal transduction involved in conjugation with cellular fusion [PMID:15620357|PMID:8384702]
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:16319894]
experiment: EXISTENCE:direct assay:GO:0004707 MAP kinase activity [PMID:15620357|PMID:8384702]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:10233162|PMID:18417610]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:10233162]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0010494 cytoplasmic stress granule [PMID:26777405]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:11781566|PMID:17952059]
experiment: EXISTENCE:direct assay:GO:0071507 pheromone response MAPK cascade [PMID:8159759]
experiment: EXISTENCE:mutant phenotype:GO:0001403 invasive growth in response to glucose limitation [PMID:10652102|PMID:15620357|PMID:8001818]
experiment: EXISTENCE:mutant phenotype:GO:0010526 negative regulation of transposition, RNA-mediated [PMID:9566871]
experiment: EXISTENCE:mutant phenotype:GO:0046827 positive regulation of protein export from nucleus [PMID:22588722]
experiment: EXISTENCE:physical interaction:GO:0043409 negative regulation of MAPK cascade [PMID:16424299]
note: Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis
codon start: 1
product: mitogen-activated serine/threonine-protein kinase FUS3
translation: MPKRIVYNISSDFQLKSLLGEGAYGVVCSATHKPTGEIVAIKKIEPFDKPLFALRTLREIKILKHFKHENIITIFNIQRPDSFENFNEVYIIQELMQTDLHRVISTQMLSDDHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLLINSNCDLKVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIGTPHSDNDLRCIESPRAREYIKSLPMYPAAPLEKMFPRVNPKGIDLLQRMLVFDPAKRITAKEALEHPYLQTYHDPNDEPEGEPIPPSFFEFDHYKEALTTKDLKKLIWNEIFS
SIO_010081: YBL016W
subclass of: SO_0000673
so part of: YBL016W
location: 192451..193512
location: region:192451-193512:1
so has part: feature:192451-193512:1:exon

NP_009537.1
type: Protein
SIO_000068: ncbiprotein

S000000112
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:192451-193512:1:exon

YBL015W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ACH1
locus tag: YBL015W
so part of: sequence
location: <194122..>195702
location: region:194122-195702:1
so has part: feature:194122-195702:1:exon
subclass of: SO_0000010

852266
type: Gene
SIO_000068: ncbigene

position:194122:1
position: 194122
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:195702:1
position: 195702
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:194122-195702:1:exon

YBL015W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ACH1
locus tag: YBL015W
product: acetyl-CoA hydrolase
transcript id: NM_001178255.1
SIO_010081: YBL015W
subclass of: SO_0000673
so part of: YBL015W
location: <194122..>195702
location: region:194122-195702:1
so has part: feature:194122-195702:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:194122-195702:1:exon

YBL015W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ACH1
locus tag: YBL015W
EC number: 3.1.2.1
experiment: EXISTENCE:direct assay:GO:0003986 acetyl-CoA hydrolase activity [PMID:12606555]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:12606555|PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:11746603]
experiment: EXISTENCE:direct assay:GO:0008775 acetate CoA-transferase activity [PMID:19298859]
experiment: EXISTENCE:mutant phenotype:GO:0006083 acetate metabolic process [PMID:8841387]
note: Protein with CoA transferase activity; particularly for CoASH transfer from succinyl-CoA to acetate; has minor acetyl-CoA-hydrolase activity; phosphorylated; required for acetate utilization and for diploid pseudohyphal growth
codon start: 1
product: acetyl-CoA hydrolase
translation: MTISNLLKQRVRYAPYLKKVKEAHELIPLFKNGQYLGWSGFTGVGTPKAVPEALIDHVEKNNLQGKLRFNLFVGASAGPEENRWAEHDMIIKRAPHQVGKPIAKAINQGRIEFFDKHLSMFPQDLTYGFYTRERKDNKILDYTIIEATAIKEDGSIVPGPSVGGSPEFITVSDKVIIEVNTATPSFEGIHDIDMPVNPPFRKPYPYLKVDDKCGVDSIPVDPEKVVAIVESTMRDQVPPNTPSDDMSRAIAGHLVEFFRNEVKHGRLPENLLPLQSGIGNIANAVIEGLAGAQFKHLTVWTEVLQDSFLDLFENGSLDYATATSVRLTEKGFDRAFANWENFKHRLCLRSQVVSNNPEMIRRLGVIAMNTPVEVDIYAHANSTNVNGSRMLNGLGGSADFLRNAKLSIMHAPSARPTKVDPTGISTIVPMASHVDQTEHDLDILVTDQGLADLRGLSPKERAREIINKCAHPDYQALLTDYLDRAEHYAKKHNCLHEPHMLKNAFKFHTNLAEKGTMKVDSWEPVD
SIO_010081: YBL015W
subclass of: SO_0000673
so part of: YBL015W
location: 194122..195702
location: region:194122-195702:1
so has part: feature:194122-195702:1:exon

NP_009538.1
type: Protein
SIO_000068: ncbiprotein

S000000111
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:194122-195702:1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(197016..197320)
location: region:197016-197320:-1
so has part: feature:197016-197320:-1:region

S000006796
type: SGD
SIO_000068: sgd

position:197016:-1
position: 197016
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:197320:-1
position: 197320
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:197016-197320:-1:region

YNCB0004W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCB0004W
so part of: sequence
location: 197494..197567
location: region:197494-197567:1
so has part: feature:197494-197567:1:exon
subclass of: SO_0000663

852267
type: Gene
SIO_000068: ncbigene

position:197494:1
position: 197494
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:197567:1
position: 197567
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:197494-197567:1:exon

YNCB0004W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCB0004W
product: tRNA-Ile
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Isoleucine tRNA (tRNA-Ile), predicted by tRNAscan-SE analysis
SIO_010081: YNCB0004W
subclass of: SO_0000673
so part of: YNCB0004W
location: 197494..197567
location: region:197494-197567:1
so has part: feature:197494-197567:1:exon

S000006600
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:197494-197567:1:exon

YNCB0005C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCB0005C
so part of: sequence
location: complement(197629..197699)
location: region:197629-197699:-1
so has part: feature:197629-197699:-1:exon
subclass of: SO_0000663

852268
type: Gene
SIO_000068: ncbigene

position:197629:-1
position: 197629
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:197699:-1
position: 197699
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:197629-197699:-1:exon

YNCB0005C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCB0005C
product: tRNA-Gly
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
experiment: EXISTENCE:direct assay:GO:0030371 translation repressor activity [PMID:27609601]
experiment: EXISTENCE:direct assay:GO:0043022 ribosome binding [PMID:27609601]
experiment: EXISTENCE:direct assay:GO:0043555 regulation of translation in response to stress [PMID:27609601]
note: Glycine tRNA (tRNA-Gly), predicted by tRNAscan-SE analysis
SIO_010081: YNCB0005C
subclass of: SO_0000673
so part of: YNCB0005C
location: complement(197629..197699)
location: region:197629-197699:-1
so has part: feature:197629-197699:-1:exon

S000006574
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:197629-197699:-1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty3 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 197714..198054
location: region:197714-198054:1
so has part: feature:197714-198054:1:region

S000006797
type: SGD
SIO_000068: sgd

position:197714:1
position: 197714
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:198054:1
position: 198054
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:197714-198054:1:region

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS231; Autonomously Replicating Sequence
so part of: sequence
location: 198313..198473
location: region:198313-198473:1
so has part: feature:198313-198473:1:region

S000118997
type: SGD
SIO_000068: sgd

position:198313:1
position: 198313
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:198473:1
position: 198473
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:198313-198473:1:region

YBL014C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RRN6
locus tag: YBL014C
so part of: sequence
location: complement(<199064..>201748)
location: region:199064-201748:-1
so has part: feature:199064-201748:-1:exon
subclass of: SO_0000010

852269
type: Gene
SIO_000068: ncbigene

position:199064:-1
position: 199064
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:201748:-1
position: 201748
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:199064-201748:-1:exon

YBL014C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RRN6
locus tag: YBL014C
product: Rrn6p
transcript id: NM_001178254.2
SIO_010081: YBL014C
subclass of: SO_0000673
so part of: YBL014C
location: complement(<199064..>201748)
location: region:199064-201748:-1
so has part: feature:199064-201748:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:199064-201748:-1:exon

YBL014C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RRN6
locus tag: YBL014C
experiment: EXISTENCE:curator inference:GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding []
experiment: EXISTENCE:direct assay:GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding [PMID:20421203]
experiment: EXISTENCE:direct assay:GO:0001179 RNA polymerase I general transcription initiation factor binding [PMID:11032814]
experiment: EXISTENCE:direct assay:GO:0042790 nucleolar large rRNA transcription by RNA polymerase I [PMID:7958901]
experiment: EXISTENCE:direct assay:GO:0070860 RNA polymerase I core factor complex [PMID:7958901|PMID:8702872|PMID:8887672]
experiment: EXISTENCE:mutant phenotype:GO:0042790 nucleolar large rRNA transcription by RNA polymerase I [PMID:7958901]
experiment: EXISTENCE:physical interaction:GO:0001179 RNA polymerase I general transcription initiation factor binding [PMID:11032814]
note: Component of the core factor (CF) rDNA transcription factor complex; CF is required for transcription of 35S rRNA genes by RNA polymerase I and is composed of Rrn6p, Rrn7p, and Rrn11p
codon start: 1
product: Rrn6p
translation: MSEGQIPSSDVLGSQLGVGVQGASLYCPQENYTTKKQEKPQWLRPVDDTLAEDALDLHIVVKSLLCDTAIRYISDDKVLQESDADDDLITSDIDEDTDNQGDTSIVVNPVIPVVPKDVHFFKKVDVGNDSMFGVNCDTPVSFQDYIPSDLLRNLDDTLQESTNSSRPMQDAFFWDPTVANRLDSQYIQTASDLRNYRDGTEIIAYASGKTGSVLNIAVLTRQNTLHLNRHNNVTSIELHSPIKSIKIPGASESIGRRSNLVGIITENSFQIFRIESVHSRSCDVMVSSSEPLYFVEIDDLQVVDFAFNPWDLQQFAIIDIKGNWSIGRIPKNFNNNNKRKLQLIDNLHGTIFDPEELSSWKRIEWFSHFQKILVFDRSKMIEIDFMNNWQTEVVQAKAWSNIRDYKRIDDKNGILLTSREIIIVGASESNDPVRRISWKHDLDPDDTTLRITVQKVKKPDHILLVAFVYSMRHKRIYMHVFSHRKANLFQSLGCSTVLEIPGGTPTGIETILTLDHIDDESRREEDADENFELVVDFLVKLRNSSEVYYYALSNTQNSEPNKQETPIIVDHPEWASLFNNADEREKESIGALVSQIKLKERERISRVQNLIEHENSHDEDKYLQDLGYRLSIATNELLESWQKTKDESILSGSLSHSKLKNLLENSDSFASIPEFSSLLDQFFQYYQDQDVTFIGFEKLLHLFLHEDVPGLDIFYNKLLQCWVLVSPQAELLTKEIVKDIIWSLARLEKPSLFEPIQNEISRSLSGPYQDIISSWDMDDINEEDESNEFNFDSQFSAPFNGRPPFNLNSQSQIPTIKSSQSSGLARRKRILKTQSQKATPLSQSTQNLSVLPDSMTPAFTLMQPPSSQISFVNDSQPRNSQKAKKKKKRIRGFG
SIO_010081: YBL014C
subclass of: SO_0000673
so part of: YBL014C
location: complement(199064..201748)
location: region:199064-201748:-1
so has part: feature:199064-201748:-1:exon

NP_009539.2
type: Protein
SIO_000068: ncbiprotein

S000000110
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:199064-201748:-1:exon

YBL013W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FMT1
locus tag: YBL013W
so part of: sequence
location: <202056..>203261
location: region:202056-203261:1
so has part: feature:202056-203261:1:exon
subclass of: SO_0000010

852270
type: Gene
SIO_000068: ncbigene

position:202056:1
position: 202056
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:203261:1
position: 203261
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:202056-203261:1:exon

YBL013W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FMT1
locus tag: YBL013W
product: methionyl-tRNA formyltransferase
transcript id: NM_001178253.1
SIO_010081: YBL013W
subclass of: SO_0000673
so part of: YBL013W
location: <202056..>203261
location: region:202056-203261:1
so has part: feature:202056-203261:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:202056-203261:1:exon

YBL013W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FMT1
locus tag: YBL013W
EC number: 2.1.2.9
experiment: EXISTENCE:direct assay:GO:0004479 methionyl-tRNA formyltransferase activity [PMID:12549912]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:5277072|PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0071951 conversion of methionyl-tRNA to N-formyl-methionyl-tRNA [PMID:12549912]
experiment: EXISTENCE:mutant phenotype:GO:0004479 methionyl-tRNA formyltransferase activity [PMID:10781559]
experiment: EXISTENCE:mutant phenotype:GO:0071951 conversion of methionyl-tRNA to N-formyl-methionyl-tRNA [PMID:10781559]
note: Methionyl-tRNA formyltransferase; catalyzes formylation of mitochondria initiator Met-tRNA and residual cytosolic Met-tRNA due to inefficient translocation into the mitochondrial matrix; starvation or stationary phase entry increases Gcn2p phosphorylation-mediated cytosolic retention of Fmt1p, enhancing N-terminal protein formylation and ultimately N-end rule pathway mediated destruction that involves the Psh1p ubiquitin ligase; potential Cdc28p substrate
codon start: 1
product: methionyl-tRNA formyltransferase
translation: MVKMRRITPTRLLFTCRYISNNASPPVQPLNVLFFGSDTFSNFSLQALNELRQNNGSCGIVDNIQVVTRSPKWCGRQKSILKYPPIFDMAEKLQLPRPITCDTKQEMLALSKLTPSRQGNPENDGSGAPFNAIIAVSFGKLIPGDLIRAVPLALNVHPSLLPRHKGSAPIQRALLEGDTYTGVTIQTLHPDRFDHGAIVAQTEPLAIATMLSKGRVNDSTADFNSEGLPRRTAILMDQLGALGAQLLGQTLRERLYLPQNRVQAPTAYKPSYAHRITTEDKRIHWARDSAAELLNKLETLGPLHAFKEATAARKDAQNSVLKRILFHECKVMRDARLDNGSKPGMFKYDDIKDCILVTCRGNLLLCVSRLQFEGFAVERAGQFMARLRKRCGALSEKLVFL
SIO_010081: YBL013W
subclass of: SO_0000673
so part of: YBL013W
location: 202056..203261
location: region:202056-203261:1
so has part: feature:202056-203261:1:exon

NP_009540.2
type: Protein
SIO_000068: ncbiprotein

S000000109
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:202056-203261:1:exon

YBL011W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: GAT2
gene: SCT1
locus tag: YBL011W
gene synonym: GAT2
so part of: sequence
location: <203538..>205817
location: region:203538-205817:1
so has part: feature:203538-205817:1:exon
subclass of: SO_0000010

852271
type: Gene
SIO_000068: ncbigene

position:203538:1
position: 203538
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:205817:1
position: 205817
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:203538-205817:1:exon

YBL011W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: GAT2
gene: SCT1
locus tag: YBL011W
gene synonym: GAT2
product: bifunctional glycerol-3-phosphate/glycerone-phosphate O-acyltransferase SCT1
transcript id: NM_001178251.1
SIO_010081: YBL011W
subclass of: SO_0000673
so part of: YBL011W
location: <203538..>205817
location: region:203538-205817:1
so has part: feature:203538-205817:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:203538-205817:1:exon

YBL011W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: GAT2
gene: SCT1
locus tag: YBL011W
gene synonym: GAT2
EC number: 2.3.1.15
EC number: 2.3.1.42
experiment: EXISTENCE:direct assay:GO:0004366 glycerol-3-phosphate O-acyltransferase activity [PMID:11544256]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:14562095|PMID:26928762|PMID:19525420]
experiment: EXISTENCE:direct assay:GO:0016287 glycerone-phosphate O-acyltransferase activity [PMID:11544256]
experiment: EXISTENCE:mutant phenotype:GO:0004366 glycerol-3-phosphate O-acyltransferase activity [PMID:11544256]
experiment: EXISTENCE:mutant phenotype:GO:0008654 phospholipid biosynthetic process [PMID:11544256]
note: Glycerol 3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase; dual substrate-specific acyltransferase of the glycerolipid biosynthesis pathway; prefers 16-carbon fatty acids; similar to Gpt2p; gene is constitutively transcribed
codon start: 1
product: bifunctional glycerol-3-phosphate/glycerone-phosphate O-acyltransferase SCT1
translation: MPAPKLTEKFASSKSTQKTTNYSSIEAKSVKTSADQAYIYQEPSATKKILYSIATWLLYNIFHCFFREIRGRGSFKVPQQGPVIFVAAPHANQFVDPVILMGEVKKSVNRRVSFLIAESSLKQPPIGFLASFFMAIGVVRPQDNLKPAEGTIRVDPTDYKRVIGHDTHFLTDCMPKGLIGLPKSMGFGEIQSIESDTSLTLRKEFKMAKPEIKTALLTGTTYKYAAKVDQSCVYHRVFEHLAHNNCIGIFPEGGSHDRTNLLPLKAGVAIMALGCMDKHPDVNVKIVPCGMNYFHPHKFRSRAVVEFGDPIEIPKELVAKYHNPETNRDAVKELLDTISKGLQSVTVTCSDYETLMVVQTIRRLYMTQFSTKLPLPLIVEMNRRMVKGYEFYRNDPKIADLTKDIMAYNAALRHYNLPDHLVEEAKVNFAKNLGLVFFRSIGLCILFSLAMPGIIMFSPVFILAKRISQEKARTALSKSTVKIKANDVIATWKILIGMGFAPLLYIFWSVLITYYLRHKPWNKIYVFSGSYISCVIVTYSALIVGDIGMDGFKSLRPLVLSLTSPKGLQKLQKDRRNLAERIIEVVNNFGSELFPDFDSAALREEFDVIDEEEEDRKTSELNRRKMLRKQKIKRQEKDSSSPIISQRDNHDAYEHHNQDSDGVSLVNSDNSLSNIPLFSSTFHRKSESSLASTSVAPSSSSEFEVENEILEEKNGLASKIAQAVLNKRIGENTAREEEEEEEEEEEEEEEEEEGKEGDA
SIO_010081: YBL011W
subclass of: SO_0000673
so part of: YBL011W
location: 203538..205817
location: region:203538-205817:1
so has part: feature:203538-205817:1:exon

NP_009542.1
type: Protein
SIO_000068: ncbiprotein

S000000107
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:203538-205817:1:exon

YBL010C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: LAA2
locus tag: YBL010C
so part of: sequence
location: complement(<206107..>206949)
location: region:206107-206949:-1
so has part: feature:206107-206949:-1:exon
subclass of: SO_0000010

852273
type: Gene
SIO_000068: ncbigene

position:206107:-1
position: 206107
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:206949:-1
position: 206949
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:206107-206949:-1:exon

YBL010C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: LAA2
locus tag: YBL010C
product: Laa2p
transcript id: NM_001178250.1
SIO_010081: YBL010C
subclass of: SO_0000673
so part of: YBL010C
location: complement(<206107..>206949)
location: region:206107-206949:-1
so has part: feature:206107-206949:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:206107-206949:-1:exon

YBL010C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: LAA2
locus tag: YBL010C
experiment: EXISTENCE:direct assay:GO:0030136 clathrin-coated vesicle [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0031503 protein-containing complex localization [PMID:30523155]
experiment: EXISTENCE:mutant phenotype:GO:0035653 clathrin-coated vesicle cargo loading, AP-1-mediated [PMID:30523155]
note: Clathrin adaptor (adaptin) accessory protein; physically interacts with and is involved in localization of clathrin adaptor protein complex-1 (AP-1); green fluorescent protein (GFP)-fusion protein colocalizes with clathrin-coated vesicles
codon start: 1
product: Laa2p
translation: MSDRDQIEPVTNALDAESDSSDDFGNFSDASVENDLYNQNSTLTTSSESVVDNCLNKILPKGEFDLEEETIKNDCFKLSKLIEDERPHVIYEQLVQLDPVLQPFIWNKSHIRRNLLHILRLSDNNGSEGVGTKREEEPLNDELFKRICDAVEKNEQTATGLFLRDNFKIDYTPPMTLKSLQKEEEREQEQHIPQLLMADFTSMDEESLRQYHDTLCQSIDFLVSKSRSLKKQQRDLLKDKTTFENVVTNLTGHTQRLQRDEIALYNKKRNKKKRFSWVGY
SIO_010081: YBL010C
subclass of: SO_0000673
so part of: YBL010C
location: complement(206107..206949)
location: region:206107-206949:-1
so has part: feature:206107-206949:-1:exon

NP_009543.1
type: Protein
SIO_000068: ncbiprotein

S000000106
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:206107-206949:-1:exon

YBL009W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ALK2
locus tag: YBL009W
so part of: sequence
location: <207194..>209224
location: region:207194-209224:1
so has part: feature:207194-209224:1:exon
subclass of: SO_0000010

852274
type: Gene
SIO_000068: ncbigene

position:207194:1
position: 207194
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:209224:1
position: 209224
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:207194-209224:1:exon

YBL009W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ALK2
locus tag: YBL009W
product: protein kinase ALK2
transcript id: NM_001178249.1
SIO_010081: YBL009W
subclass of: SO_0000673
so part of: YBL009W
location: <207194..>209224
location: region:207194-209224:1
so has part: feature:207194-209224:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:207194-209224:1:exon

YBL009W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ALK2
locus tag: YBL009W
EC number: 2.7.11.1
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:16855400]
experiment: EXISTENCE:mutant phenotype:GO:0000278 mitotic cell cycle [PMID:16855400]
experiment: EXISTENCE:mutant phenotype:GO:0044879 mitotic morphogenesis checkpoint signaling [PMID:33585466]
note: Atypical protein kinase; along with its paralog, ALK1, required for proper spindle positioning and nuclear segregation following mitotic arrest, proper organization of formins and polarisome components in mitosis, and survival after spindle assembly checkpoint delay; negatively regulates the morphogenesis checkpoint in response to polarity insults in opposition to ALK1; phosphorylated in response to DNA damage; similar to mammalian haspins
codon start: 1
product: protein kinase ALK2
translation: MNFDAVADQQMTDRRYFALEVAESDDADSSLNSSSMGSPAVDVGRKVYKITSHKGSAEDESQSFFTSSDSPTSKTRPVGKTIENDDYYGKRSSTGSSLKQLFNKININDTAHSSNKENVSQSVLSENKLLSPSKRLSKQGLTKVTNSKFRTPLRPISNQSTLSRDEPVKDFRSLKFRSGSDFKCWGDEKTSSHVHSSSVNSVNSFTSTTSSSKWKFWKNDNLLSRSLSSRSVNDQDPNFVQPKPTNSLQKKSSISSFHNSIFGGGKHTEKKRNSGFIMPDHQSTKELNHKHSSSNLSFRSLKHKTSHSSLNKLKVRRKGNTQELNHPIKKTCQISLPVPDQVSKDKIQLKLKNSTSLASLSSEVTPINTLDYNDSILQQILQLCDVKYILHDLREAQSLGLFTLNTRSVQLSHNFWQTYHSDMQTSLICKKVCLGALSDLTTSNLISLHELKSLRLIQGTSGVANLLQAYVVPSNQCENDQNLILYLFFKYQGTPLSRCSNIDYSQALSIFWQCSSILYVAESKFQLEHRNLTLDHILIDSKGNVTLIDMKCCRFLNIDNNKASYTRLDHHYFFQGRGTLQFEIYELMRSMLPQPISWATFEPRTNLLWLYHLSSSLLKMAKKAVVSGALNREENILIELTHLLDPARKHSKTIFKKELVIRTCGDLLSLKGEIMQ
SIO_010081: YBL009W
subclass of: SO_0000673
so part of: YBL009W
location: 207194..209224
location: region:207194-209224:1
so has part: feature:207194-209224:1:exon

NP_009544.1
type: Protein
SIO_000068: ncbiprotein

S000000105
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:207194-209224:1:exon

YBL008W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBL008W-A
so part of: sequence
location: <209409..>209648
location: region:209409-209648:1
so has part: feature:209409-209648:1:exon
subclass of: SO_0000010

1466442
type: Gene
SIO_000068: ncbigene

position:209409:1
position: 209409
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:209648:1
position: 209648
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:209409-209648:1:exon

YBL008W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBL008W-A
product: uncharacterized protein
transcript id: NM_001184539.1
SIO_010081: YBL008W-A
subclass of: SO_0000673
so part of: YBL008W-A
location: <209409..>209648
location: region:209409-209648:1
so has part: feature:209409-209648:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:209409-209648:1:exon

YBL008W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBL008W-A
note: hypothetical protein; identified by fungal homology and RT-PCR
codon start: 1
product: uncharacterized protein
translation: MKMNPCTVILCKSLFFFCLFQVDCYCNRKNIQNQSSRIATKIKRSYWFRWQKHIILANIHKIIKAYQRSIIKLPVTKGL
SIO_010081: YBL008W-A
subclass of: SO_0000673
so part of: YBL008W-A
location: 209409..209648
location: region:209409-209648:1
so has part: feature:209409-209648:1:exon

NP_878046.1
type: Protein
SIO_000068: ncbiprotein

S000028529
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:209409-209648:1:exon

YBL008W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HIR1
locus tag: YBL008W
so part of: sequence
location: <209653..>212175
location: region:209653-212175:1
so has part: feature:209653-212175:1:exon
subclass of: SO_0000010

852275
type: Gene
SIO_000068: ncbigene

position:209653:1
position: 209653
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:212175:1
position: 212175
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:209653-212175:1:exon

YBL008W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HIR1
locus tag: YBL008W
product: Hir1p
transcript id: NM_001178248.2
SIO_010081: YBL008W
subclass of: SO_0000673
so part of: YBL008W
location: <209653..>212175
location: region:209653-212175:1
so has part: feature:209653-212175:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:209653-212175:1:exon

YBL008W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: HIR1
locus tag: YBL008W
experiment: EXISTENCE:direct assay:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:9001207]
experiment: EXISTENCE:direct assay:GO:0000417 HIR complex [PMID:16264190|PMID:16303565]
experiment: EXISTENCE:direct assay:GO:0000775 chromosome, centromeric region [PMID:11782447]
experiment: EXISTENCE:direct assay:GO:0003677 DNA binding [PMID:16264190]
experiment: EXISTENCE:direct assay:GO:0003714 transcription corepressor activity [PMID:9001207]
experiment: EXISTENCE:direct assay:GO:0006325 chromatin organization [PMID:16264190|PMID:16303565]
experiment: EXISTENCE:genetic interaction:GO:0006368 transcription elongation by RNA polymerase II promoter [PMID:16449659]
experiment: EXISTENCE:genetic interaction:GO:0016480 negative regulation of transcription by RNA polymerase III [PMID:23962978]
experiment: EXISTENCE:mutant phenotype:GO:0016480 negative regulation of transcription by RNA polymerase III [PMID:23962978]
experiment: EXISTENCE:mutant phenotype:GO:0031491 nucleosome binding [PMID:16264190]
experiment: EXISTENCE:physical interaction:GO:0000417 HIR complex [PMID:16264190]
note: Subunit of the HIR complex; HIR is a nucleosome assembly complex involved in regulation of histone gene transcription; contributes to nucleosome formation, heterochromatic gene silencing, and formation of functional kinetochores
codon start: 1
product: Hir1p
translation: MKVVKFPWLAHREESRKYEIYTVDVSHDGKRLATGGLDGKIRIWSIDSILRCMELESLTPEIPLPQDLQMPLCSMSRHTGSITCVKFSPDGKYLASGSDDRILLIWALDEEQSSQPAFGSEHEREHWTVRKRLVAHDNDIQDICWAPDSSILVTVGLDRSVIVWNGSTFEKLKRFDVHQSLVKGVVFDPANKYFATTSDDRTMKIFRYHKTGDISFTIEHIITEPFKESPLTTYFRRPSWSPDGQHIAVPNATNGPVSSVAIVNRGTWDTNVSLIGHDAPTEVARFNPRLFERNAGVKQKKDDDPENALVGQNDDKVHHFDKNIDSVVATAGQDKSLAVWSTSRPRPILVAFDIANKSITDMSWNPDGSLLFVASLDSSITLFKFENNELGKPIPLEKNMEQLYRYGVDKDSLDFPESINQLLLEDQTKSFKHTKISTSKLGENHPTLATNSASNQKDNNDASVSRSEHINILIPKRKKDAILNKAVTLKSGKKRVAPTLISTSSSSPFSNGIKKPTLDSKRIENNVKSSTKTINSKNTLLNVPEGVEKKISISSFPLPRLGIHSLIMGTKERSAWKISNSELENDDADNAGGKGSDGTSNSIDDIAVLSEEENDFHRMTLNAKLTQEKIWSEEPTTRCLLQSDVIPDTDVVVLEGGSLDDIAVLEIRNGVERSIQFDSEALLDNPTRILGYQGGKRTIETFIPEVIICAIGSKDCKCWCLASANGSIYILSYNGQQRIPKICLGHKVIKMVTSSKYLLVLTERGLFFAWDLLDLKLVLRNVPILPILNGQPIHGNKVRINKVIKCFRLDGSSCDLLLEVGDPKNVYKWTKDLGCWSLYK
SIO_010081: YBL008W
subclass of: SO_0000673
so part of: YBL008W
location: 209653..212175
location: region:209653-212175:1
so has part: feature:209653-212175:1:exon

NP_009545.2
type: Protein
SIO_000068: ncbiprotein

S000000104
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:209653-212175:1:exon

YBL007C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SLA1
locus tag: YBL007C
so part of: sequence
location: complement(<212632..>216366)
location: region:212632-216366:-1
so has part: feature:212632-216366:-1:exon
subclass of: SO_0000010

852276
type: Gene
SIO_000068: ncbigene

position:212632:-1
position: 212632
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:216366:-1
position: 216366
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:212632-216366:-1:exon

YBL007C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SLA1
locus tag: YBL007C
product: cytoskeletal protein-binding protein SLA1
transcript id: NM_001178247.1
SIO_010081: YBL007C
subclass of: SO_0000673
so part of: YBL007C
location: complement(<212632..>216366)
location: region:212632-216366:-1
so has part: feature:212632-216366:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:212632-216366:-1:exon

YBL007C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SLA1
locus tag: YBL007C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:17286805]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005938 cell cortex [PMID:11950888]
experiment: EXISTENCE:direct assay:GO:0030479 actin cortical patch [PMID:10198057|PMID:16824951]
experiment: EXISTENCE:direct assay:GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation [PMID:12814545|PMID:22973053]
experiment: EXISTENCE:direct assay:GO:0043130 ubiquitin binding [PMID:17244534]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:19053807]
experiment: EXISTENCE:direct assay:GO:0140224 SLAC complex [PMID:22973053]
experiment: EXISTENCE:direct assay:GO:1990964 actin cytoskeleton-regulatory complex [PMID:10594004]
experiment: EXISTENCE:mutant phenotype:GO:0000147 actin cortical patch assembly [PMID:10198057|PMID:8335689]
experiment: EXISTENCE:mutant phenotype:GO:0005634 nucleus [PMID:17286805]
experiment: EXISTENCE:mutant phenotype:GO:0006897 endocytosis [PMID:11940605|PMID:17363896]
experiment: EXISTENCE:mutant phenotype:GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation [PMID:12814545]
experiment: EXISTENCE:mutant phenotype:GO:0140312 cargo adaptor activity [PMID:11940605|PMID:17065552|PMID:17363896]
experiment: EXISTENCE:physical interaction:GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation [PMID:22973053]
experiment: EXISTENCE:physical interaction:GO:0140224 SLAC complex [PMID:22973053]
note: Cytoskeletal protein binding protein; required for assembly of the cortical actin cytoskeleton; interacts with proteins regulating actin dynamics and proteins required for endocytosis; found in the nucleus and cell cortex; has 3 SH3 domains
codon start: 1
product: cytoskeletal protein-binding protein SLA1
translation: MTVFLGIYRAVYAYEPQTPEELAIQEDDLLYLLQKSDIDDWWTVKKRVIGSDSEEPVGLVPSTYIEEAPVLKKVRAIYDYEQVQNADEELTFHENDVFDVFDDKDADWLLVKSTVSNEFGFIPGNYVEPENGSTSKQEQAPAAAEAPAATPAAAPASAAVLPTNFLPPPQHNDRARMMQSKEDQAPDEDEEGPPPAMPARPTATTETTDATAAAVRSRTRLSYSDNDNDDEEDDYYYNSNSNNVGNHEYNTEYHSWNVTEIEGRKKKKAKLSIGNNKINFIPQKGTPHEWSIDKLVSYDNEKKHMFLEFVDPYRSLELHTGNTTTCEEIMNIIGEYKGASRDPGLREVEMASKSKKRGIVQYDFMAESQDELTIKSGDKVYILDDKKSKDWWMCQLVDSGKSGLVPAQFIEPVRDKKHTESTASGIIKSIKKNFTKSPSRSRSRSRSKSNANASWKDDELQNDVVGSAAGKRSRKSSLSSHKKNSSATKDFPNPKKSRLWVDRSGTFKVDAEFIGCAKGKIHLHKANGVKIAVAADKLSNEDLAYVEKITGFSLEKFKANDGSSSRGTDSRDSERERRRRLKEQEEKERDRRLKERELYELKKARELLDEERSRLQEKELPPIKPPRPTSTTSVPNTTSVPPAESSNNNNSSNKYDWFEFFLNCGVDVSNCQRYTINFDREQLTEDMMPDINNSMLRTLGLREGDIVRVMKHLDKKFGRENIASIPTNATGNMFSQPDGSLNVATSPETSLPQQLLPQTTSPAQTAPSTSAETDDAWTVKPASKSESNLLSKKSEFTGSMQDLLDLQPLEPKKAAASTPEPNLKDLEPVKTGGTTVPAAPVSSAPVSSAPAPLDPFKTGGNNILPLSTGFVMMPMITGGDMLPMQRTGGFVVPQTTFGMQSQVTGGILPVQKTGNGLIPISNTGGAMMPQTTFGAAATVLPLQKTGGGLIPIATTGGAQFPQTSFNVQGQQQLPTGSILPVQKTANGLISANTGVSMPTVQRTGGTMIPQTSFGVSQQLTGGAMMTQPQNTGSAMMPQTSFNAVPQITGGAMMPQTSFNALPQVTGGAMMPLQRTGGALNTFNTGGAMIPQTSFSSQAQNTGGFRPQSQFGLTLQKTGGIAPLNQNQFTGGAMNTLSTGGVLQQQQPQTMNTFNTGGVMQELQMMTTFNTGGAMQQPQMMNTFNTDGIMQQPQMMNTFNTGGAMQQPQQQALQNQPTGFGFGNGPQQSRQANIFNATASNPFGF
SIO_010081: YBL007C
subclass of: SO_0000673
so part of: YBL007C
location: complement(212632..216366)
location: region:212632-216366:-1
so has part: feature:212632-216366:-1:exon

NP_009546.1
type: Protein
SIO_000068: ncbiprotein

S000000103
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:212632-216366:-1:exon

YBL006C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RSC14
gene: LDB7
locus tag: YBL006C
gene synonym: RSC14
so part of: sequence
location: complement(<216587..>217129)
location: region:216587-217129:-1
so has part: feature:216587-217129:-1:exon
subclass of: SO_0000010

852277
type: Gene
SIO_000068: ncbigene

position:216587:-1
position: 216587
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:217129:-1
position: 217129
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:216587-217129:-1:exon

YBL006C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RSC14
gene: LDB7
locus tag: YBL006C
gene synonym: RSC14
product: Ldb7p
transcript id: NM_001178246.1
SIO_010081: YBL006C
subclass of: SO_0000673
so part of: YBL006C
location: complement(<216587..>217129)
location: region:216587-217129:-1
so has part: feature:216587-217129:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:216587-217129:-1:exon

YBL006C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RSC14
gene: LDB7
locus tag: YBL006C
gene synonym: RSC14
experiment: EXISTENCE:direct assay:GO:0006337 nucleosome disassembly [PMID:16492771]
experiment: EXISTENCE:direct assay:GO:0006338 chromatin remodeling [PMID:12183366]
experiment: EXISTENCE:direct assay:GO:0006368 transcription elongation by RNA polymerase II promoter [PMID:17081996]
experiment: EXISTENCE:direct assay:GO:0016586 RSC-type complex [PMID:10619019|PMID:12183366]
experiment: EXISTENCE:genetic interaction:GO:0016586 RSC-type complex [PMID:16204215]
experiment: EXISTENCE:mutant phenotype:GO:0016586 RSC-type complex [PMID:16204215]
experiment: EXISTENCE:physical interaction:GO:0016586 RSC-type complex [PMID:16204215]
note: Component of the RSC chromatin remodeling complex; interacts with Rsc3p, Rsc30p, Npl6p, and Htl1p to form a module important for a broad range of RSC functions
codon start: 1
product: Ldb7p
translation: MSGSNMGYYDVLAGLSALEKSSQVVFSATELQQLTQQSHATDKGIEGSENSKAKVSKPKRVAVHGYLGGKVSLADAAQVEYEVGHSLLGSYVPRQQLEALSSVDFSHHFHRTLECKAALETHDVFLAGAGQLSLPFQSHIESPRNSEAKRKRKVIICKRCQSRFIGSHRRSQLREHACVD
SIO_010081: YBL006C
subclass of: SO_0000673
so part of: YBL006C
location: complement(216587..217129)
location: region:216587-217129:-1
so has part: feature:216587-217129:-1:exon

NP_009547.2
type: Protein
SIO_000068: ncbiprotein

S000000102
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:216587-217129:-1:exon

YBL005W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: AMY2
alternative label: TPE2
gene: PDR3
locus tag: YBL005W
gene synonym: AMY2; TPE2
so part of: sequence
location: <217470..>220400
location: region:217470-220400:1
so has part: feature:217470-220400:1:exon
subclass of: SO_0000010

852278
type: Gene
SIO_000068: ncbigene

position:217470:1
position: 217470
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:220400:1
position: 220400
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:217470-220400:1:exon

YBL005W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: AMY2
alternative label: TPE2
gene: PDR3
locus tag: YBL005W
gene synonym: AMY2; TPE2
product: drug-responsive transcription factor PDR3
transcript id: NM_001178245.1
SIO_010081: YBL005W
subclass of: SO_0000673
so part of: YBL005W
location: <217470..>220400
location: region:217470-220400:1
so has part: feature:217470-220400:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:217470-220400:1:exon

YBL005W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: AMY2
alternative label: TPE2
gene: PDR3
locus tag: YBL005W
gene synonym: AMY2; TPE2
experiment: EXISTENCE:direct assay:GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding [PMID:8798494]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:11136452|PMID:11914276|PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276]
experiment: EXISTENCE:genetic interaction:GO:2001040 positive regulation of cellular response to drug [PMID:8078477]
experiment: EXISTENCE:mutant phenotype:GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific [PMID:8798494|PMID:9428726]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:8798494|PMID:9428726]
experiment: EXISTENCE:mutant phenotype:GO:2001040 positive regulation of cellular response to drug [PMID:8078477|PMID:9767597]
note: Transcriptional activator of the pleiotropic drug resistance network; regulates expression of ATP-binding cassette (ABC) transporters through binding to cis-acting PDRE sites (PDR responsive elements); has a role in response to drugs and organic solvents; post-translationally up-regulated in cells lacking functional mitochondrial genome; involved in diauxic shift; relative distribution to nucleus increases upon DNA replication stress; APCC(Cdh1) substrate
codon start: 1
product: drug-responsive transcription factor PDR3
translation: MKVKKSTRSKVSTACVNCRKRKIKCTGKYPCTNCISYDCTCVFLKKHLPQKEDSSQSLPTTAVAPPSSHANVEASADVQHLDTAIKLDNQYYFKLMNDLIQTPVSPSATHAPDTSNNPTNDNNILFKDDSKYQNQLVTYQNILTNLYALPPCDDTQLLIDKTKSQLNNLINSWNPEINYPKLSSFSPRPQRSIETYLLTNKYRNKIHMTRFSFWTDQMVKSQSPDSFLATTPLVDEVFGLFSPIQAFSLRGIGYLIKKNIENTGSSMLIDTKETIYLILRLFDLCYEHLIQGCISISNPLENYLQKIKQTPTTTASASLPTSPAPLSNDLVISVIHQLPQPFIQSITGFTTTQLIENLHDSFSMFRIVTQMYAQHRKRFAEFLNQAFSLPHQEKSVLFSSFCSSEYLLSTLCYAYYNVTLYHMLDINTLDYLEILVSLLEIQNEIDERFGFEKMLEVAVTCSTKMGLSRWEYYVGIDENTAERRRKIWWKIYSLEKRFLTDLGDLSLINEHQMNCLLPKDFRDMGFINHKEFLTKIGTSSLSPSSPKLKNLSLSRLIEYGELAIAQIVGDFFSETLYNEKFTSLEVSVKPTIIRQKLLEKVFEDIESFRLKLAKIKLHTSRVFQVAHCKYPEYPKNDLIEAAKFVSYHKNTWFSILGAVNNLIARLSEDPEVITEQSMKYANEMFQEWREINQFLIQVDTDFIVWACLDFYELIFFVMASKFYVEDPHITLEDVINTLKVFKRITNIISFFNNNLDEKDYDCQTFREFSRSSSLVAISIRIIFLKYCYAEQIDRAEFIERLKEVEPGLSDLLREFFDTRSFIYRYMLKSVEKSGFHLIIRKMLESDYKFLYRDKLATGNIPDQGNSSQISQLYDSTAPSYNNASASAANSPLKLSSLLNSGEESYTQDASENVPCNLRHQDRSLQQTKRQHSAPSQISANENNIYNLGTLEEFVSSGDLTDLYHTLWNDNTSYPFL
SIO_010081: YBL005W
subclass of: SO_0000673
so part of: YBL005W
location: 217470..220400
location: region:217470-220400:1
so has part: feature:217470-220400:1:exon

NP_009548.1
type: Protein
SIO_000068: ncbiprotein

S000000101
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:217470-220400:1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 220895..221036
location: region:220895-221036:1
so has part: feature:220895-221036:1:region

S000006804
type: SGD
SIO_000068: sgd

position:220895:1
position: 220895
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:221036:1
position: 221036
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:220895-221036:1:region

mobile_element
type: Mobile Element
subclass of: SO_0001037
RO_0002162: 559292
note: YBLWTy1-1; Ty1 element, LTR retrotransposon of the Copia (Pseudoviridae) group; contains co-transcribed genes TYA Gag and TYB Pol, encoding proteins involved in structure and function of virus-like particles, flanked by two direct repeats
mobile element type: retrotransposon:YBLWTy1-1
so part of: sequence
location: 221037..226952
location: region:221037-226952:1
so has part: feature:221037-226952:1:region

S000006808
type: SGD
SIO_000068: sgd

position:221037:1
position: 221037
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:226952:1
position: 226952
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:221037-226952:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 221037..221370
location: region:221037-221370:1
so has part: feature:221037-221370:1:region

S000006805
type: SGD
SIO_000068: sgd

position:221370:1
position: 221370
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:221037-221370:1:region

YBL005W-B
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBL005W-B
so part of: sequence
location: <221330..>226598
location: region:221330-226598:1
so has part: feature:221330-226598:1:exon
subclass of: SO_0000010

852280
type: Gene
SIO_000068: ncbigene

position:221330:1
position: 221330
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:226598:1
position: 226598
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:221330-226598:1:exon

YBL005W-B
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBL005W-B
product: gag-pol fusion protein
transcript id: NM_001180048.2
SIO_010081: YBL005W-B
subclass of: SO_0000673
so part of: YBL005W-B
location: <221330..>226598
location: region:221330-226598:1
so has part: feature:221330-226598:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:221330-226598:1:exon

YBL005W-B
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBL005W-B
EC number: 2.7.7.7
EC number: 2.7.7.49
EC number: 3.1.26.4
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:9448009]
ribosomal slippage: true
note: Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes
codon start: 1
product: gag-pol fusion protein
translation: MESQQLSQHSPIFHGSACASVTSKEVQTTQDPLDISASKTEECEKVSTQANSQQPTTPPSSAVPENHHHASPQAAQVPLPQNGPYPQQRMMNTQQANISGWPVYGHPSLMPYPPYQMSPMYAPPGAQSQFTQYPQYVGTHLNTPSPESGNSFPDSSSAKSNMTSTNQHVRPPPILTSPNDFLNWVKIYIKFLQNSNLGDIIPTATRKAVRQMTDDELTFLCHTFQLFAPSQFLPPWVKDILSVDYTDIMKILSKSINKMQSDTQEVNDITTLATLHYNGSTPADAFEAEVTNILDRLNNNGIPINNKVACQFIMRGLSGEYKFLPYARHRCIHMTVADLFSDIHSMYEEQQESKRNKSTYRRSPSDEKKDSRTYTNTTKPKSITRNSQKPNNSQSRTARAHNVSTFNNSPGPDNDLIRGSTTEPIQLKNTHDLHLGQELTESTVNHTNHSDDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQDNTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWVSKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNESDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKSAPSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSEYTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFSAIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLTASYQSFIASNEIQQSNDLNIESDHDFQSDIELYPEQPRNVLSKAVSPTDSTPPSTHTEDSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISDIESTDSGGMHRLDVPLLAPMSQSNTHESSYASKSKDFRHSDSYSDNETNHTNVPISSTGGTNNKTVPQTSEQETEKRIIHRSPSIDTSSSESNSLHHVVPIKTSDTCPKENTEESIIADLPLPDLPPEPPTELSDSFKELPPINSRQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSLEPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLLKMKTWDTDKYYDRKEIDPKRVINSMFIFNRKRDGTHKARFVARGDIQHPDTYDSGMQSNTVHHYALMTSLSLALDNNYHITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLKKSLYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMVLFSKNLNSNKRIIDKLKMQYDTKIINLGESDEEIQYDILGLEIKYQRGKYMKLGMENSLTEKIPKLNVPLNPKGRKLSAPGQPGLYIDQQELELEEDDYKMKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSKQVLDMTYELIQFIWNTRDKQLIWHKSKPVKPTNKLVVISDASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSYLIQELDKKPITKGLLTDSKSTISIIISNNEEKFRNRFFGTKAMRLRDEVSGNHLHVCYIETKKNIADVMTKPLPIKTFKLLTNKWIH
SIO_010081: YBL005W-B
subclass of: SO_0000673
so part of: YBL005W-B
location: join(221330..222634,222636..226598)
location: region:221330-226598:1
so has part: feature:221330-222634:1:exon
so has part: feature:222636-226598:1:exon

NP_009549.1
type: Protein
SIO_000068: ncbiprotein

S000002147
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:221330-222634:1:exon

position:222634:1
position: 222634
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:222636-226598:1:exon

position:222636:1
position: 222636
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YBL005W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBL005W-A
so part of: sequence
location: <221330..>222652
location: region:221330-222652:1
so has part: feature:221330-222652:1:exon
subclass of: SO_0000010

852279
type: Gene
SIO_000068: ncbigene

position:222652:1
position: 222652
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:221330-222652:1:exon

YBL005W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBL005W-A
product: gag protein
transcript id: NM_001180047.1
SIO_010081: YBL005W-A
subclass of: SO_0000673
so part of: YBL005W-A
location: <221330..>222652
location: region:221330-222652:1
so has part: feature:221330-222652:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:221330-222652:1:exon

YBL005W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBL005W-A
note: Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag
codon start: 1
product: gag protein
translation: MESQQLSQHSPIFHGSACASVTSKEVQTTQDPLDISASKTEECEKVSTQANSQQPTTPPSSAVPENHHHASPQAAQVPLPQNGPYPQQRMMNTQQANISGWPVYGHPSLMPYPPYQMSPMYAPPGAQSQFTQYPQYVGTHLNTPSPESGNSFPDSSSAKSNMTSTNQHVRPPPILTSPNDFLNWVKIYIKFLQNSNLGDIIPTATRKAVRQMTDDELTFLCHTFQLFAPSQFLPPWVKDILSVDYTDIMKILSKSINKMQSDTQEVNDITTLATLHYNGSTPADAFEAEVTNILDRLNNNGIPINNKVACQFIMRGLSGEYKFLPYARHRCIHMTVADLFSDIHSMYEEQQESKRNKSTYRRSPSDEKKDSRTYTNTTKPKSITRNSQKPNNSQSRTARAHNVSTFNNSPGPDNDLIRGSTTEPIQLKNTHDLHLRPGTY
SIO_010081: YBL005W-A
subclass of: SO_0000673
so part of: YBL005W-A
location: 221330..222652
location: region:221330-222652:1
so has part: feature:221330-222652:1:exon

NP_009550.1
type: Protein
SIO_000068: ncbiprotein

S000002146
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:221330-222652:1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 226621..226952
location: region:226621-226952:1
so has part: feature:226621-226952:1:region

S000006806
type: SGD
SIO_000068: sgd

position:226621:1
position: 226621
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:226621-226952:1:region

YNCB0006W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCB0006W
so part of: sequence
location: 227075..227156
location: region:227075-227156:1
so has part: feature:227075-227156:1:exon
subclass of: SO_0000663

852281
type: Gene
SIO_000068: ncbigene

position:227075:1
position: 227075
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:227156:1
position: 227156
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:227075-227156:1:exon

YNCB0006W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCB0006W
product: tRNA-Ser
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
experiment: EXISTENCE:direct assay:GO:0030371 translation repressor activity [PMID:27609601]
experiment: EXISTENCE:direct assay:GO:0043022 ribosome binding [PMID:27609601]
experiment: EXISTENCE:direct assay:GO:0043555 regulation of translation in response to stress [PMID:27609601]
note: Serine tRNA (tRNA-Ser), predicted by tRNAscan-SE analysis
SIO_010081: YNCB0006W
subclass of: SO_0000673
so part of: YNCB0006W
location: 227075..227156
location: region:227075-227156:1
so has part: feature:227075-227156:1:exon

S000006720
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:227075-227156:1:exon

YBL004W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: UTP20
locus tag: YBL004W
so part of: sequence
location: <227636..>235117
location: region:227636-235117:1
so has part: feature:227636-235117:1:exon
subclass of: SO_0000010

852282
type: Gene
SIO_000068: ncbigene

position:227636:1
position: 227636
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:235117:1
position: 235117
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:227636-235117:1:exon

YBL004W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: UTP20
locus tag: YBL004W
product: Utp20p
transcript id: NM_001178244.1
SIO_010081: YBL004W
subclass of: SO_0000673
so part of: YBL004W
location: <227636..>235117
location: region:227636-235117:1
so has part: feature:227636-235117:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:227636-235117:1:exon

YBL004W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: UTP20
locus tag: YBL004W
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0005654 nucleoplasm [PMID:17652137]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:15590835|PMID:17652137|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:17652137|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0030686 90S preribosome [PMID:17652137|PMID:12150911]
experiment: EXISTENCE:direct assay:GO:0030688 preribosome, small subunit precursor [PMID:17652137]
experiment: EXISTENCE:direct assay:GO:0032040 small-subunit processome [PMID:15590835]
experiment: EXISTENCE:mutant phenotype:GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:15590835|PMID:17652137]
experiment: EXISTENCE:mutant phenotype:GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:15590835|PMID:17652137]
experiment: EXISTENCE:mutant phenotype:GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:17652137|PMID:15590835]
note: Component of the small-subunit (SSU) processome; SSU processome is involved in the biogenesis of the 18S rRNA
codon start: 1
product: Utp20p
translation: MAKQRQTTKSSKRYRYSSFKARIDDLKIEPARNLEKRVHDYVESSHFLASFDQWKEINLSAKFTEFAAEIEHDVQTLPQILYHDKKIFNSLVSFINFHDEFSLQPLLDLLAQFCHDLGPDFLKFYEEAIKTLINLLDAAIEFESSNVFEWGFNCLAYIFKYLSKFLVKKLVLTCDLLIPLLSHSKEYLSRFSAEALSFLVRKCPVSNLREFVRSVFEKLEGDDEQTNLYEGLLILFTESMTSTQETLHSKAKAIMSVLLHEALTKSSPERSVSLLSDIWMNISKYASIESLLPVYEVMYQDFNDSLDATNIDRILKVLTTIVFSESGRKIPDWNKITILIERIMSQSENCASLSQDKVAFLFALFIRNSDVKTLTLFHQKLFNYALTNISDCFLEFFQFALRLSYERVFSFNGLKFLQLFLKKNWQSQGKKIALFFLEVDDKPELQKVREVNFPEEFILSIRDFFVTAEINDSNDLFEIYWRAIIFKYSKLQNTEIIIPLLERIFSTFASPDNFTKDMVGTLLKIYRKEDDASGNNLLKTILDNYENYKESLNFLRGWNKLVSNLHPSESLKGLMSHYPSLLLSLTDNFMLPDGKIRYETLELMKTLMILQGMQVPDLLSSCMVIEEIPLTLQNARDLTIRIKNVGAEFGKTKTDKLVSSFFLKYLFGLLTVRFSPVWTGVFDTLPNVYTKDEALVWKLVLSFIKLPDENQNLDYYQPLLEDGANKVLWDSSVVRLRDTIDTFSHIWSKYSTQNTSIISTTIERRGNTTYPILIRNQALKVMLSIPQVAENHFVDIAPFVYNDFKTYKDEEDMENERVITGSWTEVDRNVFLKTLSKFKNIKNVYSATELHDHLMVLLGSRNTDVQKLALDALLAYKNPTLNKYRDNLKNLLDDTLFKDEITTFLTENGSQSIKAEDEKVVMPYVLRIFFGRAQVPPTSGQKRSRKIAVISVLPNFKKPYINDFLSLASERLDYNYFFGNSHQINSSKATLKTIRRMTGFVNIVNSTLSVLRTNFPLHTNSVLQPLIYSIAMAYYVLDTESTEEVHLRKMASNLRQQGLKCLSSVFEFVGNTFDWSTSMEDIYAVVVKPRISHFSDENLQQPSSLLRLFLYWAHNPSLYQFLYYDEFATATALMDTISNQHVKEAVIGPIIEAADSIIRNPVNDDHYVDLVTLICTSCLKILPSLYVKLSDSNSISTFLNLLVSITEMGFIQDDHVRSRLISSLISILKGKLKKLQENDTQKILKILKLIVFNYNCSWSDIEELYTTISSLFKTFDERNLRVSLTELFIELGRKVPELESISKLVADLNSYSSSRMHEYDFPRILSTFKGLIEDGYKSYSELEWLPLLFTFLHFINNKEELALRTNASHAIMKFIDFINEKPNLNEASKSISMLKDILLPNIRIGLRDSLEEVQSEYVSVLSYMVKNTKYFTDFEDMAILLYNGDEEADFFTNVNHIQLHRRQRAIKRLGEHAHQLKDNSISHYLIPMIEHYVFSDDERYRNIGNETQIAIGGLAQHMSWNQYKALLRRYISMLKTKPNQMKQAVQLIVQLSVPLRETLRIVRDGAESKLTLSKFPSNLDEPSNFIKQELYPTLSKILGTRDDETIIERMPIAEALVNIVLGLTNDDITNFLPSILTNICQVLRSKSEELRDAVRVTLGKISIILGAEYLVFVIKELMATLKRGSQIHVLSYTVHYILKSMHGVLKHSDLDTSSSMIVKIIMENIFGFAGEEKDSENYHTKVKEIKSNKSYDAGEILASNISLTEFGTLLSPVKALLMVRINLRNQNKLSELLRRYLLGLNHNSDSESESILKFCHQLFQESEMSNSPQIPKKKVKDQVDEKEDFFLVNLESKSYTINSNSLLLNSTLQKFALDLLRNVITRHRSFLTVSHLEGFIPFLRDSLLSENEGVVISTLRILITLIRLDFSDESSEIFKNCARKVLNIIKVSPSTSSELCQMGLKFLSAFIRHTDSTLKDTALSYVLGRVLPDLNEPSRQGLAF…
SIO_010081: YBL004W
subclass of: SO_0000673
so part of: YBL004W
location: 227636..235117
location: region:227636-235117:1
so has part: feature:227636-235117:1:exon

NP_009551.2
type: Protein
SIO_000068: ncbiprotein

S000000100
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:227636-235117:1:exon

YBL003C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: H2A2
gene: HTA2
locus tag: YBL003C
gene synonym: H2A2
so part of: sequence
location: complement(<235394..>235792)
location: region:235394-235792:-1
so has part: feature:235394-235792:-1:exon
subclass of: SO_0000010

852283
type: Gene
SIO_000068: ncbigene

position:235394:-1
position: 235394
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:235792:-1
position: 235792
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:235394-235792:-1:exon

YBL003C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: H2A2
gene: HTA2
locus tag: YBL003C
gene synonym: H2A2
product: histone H2A
transcript id: NM_001178243.1
SIO_010081: YBL003C
subclass of: SO_0000673
so part of: YBL003C
location: complement(<235394..>235792)
location: region:235394-235792:-1
so has part: feature:235394-235792:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:235394-235792:-1:exon

YBL003C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: H2A2
gene: HTA2
locus tag: YBL003C
gene synonym: H2A2
experiment: EXISTENCE:direct assay:GO:0031298 replication fork protection complex [PMID:16531994]
experiment: EXISTENCE:mutant phenotype:GO:0006281 DNA repair [PMID:15781691]
note: Histone H2A; core histone protein required for chromatin assembly and chromosome function; one of two nearly identical (see also HTA1) subtypes; DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p
codon start: 1
product: histone H2A
translation: MSGGKGGKAGSAAKASQSRSAKAGLTFPVGRVHRLLRRGNYAQRIGSGAPVYLTAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDDELNKLLGNVTIAQGGVLPNIHQNLLPKKSAKTAKASQEL
SIO_010081: YBL003C
subclass of: SO_0000673
so part of: YBL003C
location: complement(235394..235792)
location: region:235394-235792:-1
so has part: feature:235394-235792:-1:exon

NP_009552.1
type: Protein
SIO_000068: ncbiprotein

S000000099
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:235394-235792:-1:exon

YBL002W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HTB2
locus tag: YBL002W
so part of: sequence
location: <236492..>236887
location: region:236492-236887:1
so has part: feature:236492-236887:1:exon
subclass of: SO_0000010

852284
type: Gene
SIO_000068: ncbigene

position:236492:1
position: 236492
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:236887:1
position: 236887
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:236492-236887:1:exon

YBL002W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HTB2
locus tag: YBL002W
product: histone H2B
transcript id: NM_001178242.1
SIO_010081: YBL002W
subclass of: SO_0000673
so part of: YBL002W
location: <236492..>236887
location: region:236492-236887:1
so has part: feature:236492-236887:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:236492-236887:1:exon

YBL002W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: HTB2
locus tag: YBL002W
experiment: EXISTENCE:direct assay:GO:0031298 replication fork protection complex [PMID:16531994]
note: Histone H2B; core histone protein required for chromatin assembly and chromosome function; nearly identical to HTB1; Rad6p-Bre1p-Lge1p mediated ubiquitination regulates reassembly after DNA replication, transcriptional activation, meiotic DSB formation and H3 methylation
codon start: 1
product: histone H2B
translation: MSSAAEKKPASKAPAEKKPAAKKTSTSVDGKKRSKVRKETYSSYIYKVLKQTHPDTGISQKSMSILNSFVNDIFERIATEASKLAAYNKKSTISAREIQTAVRLILPGELAKHAVSEGTRAVTKYSSSTQA
SIO_010081: YBL002W
subclass of: SO_0000673
so part of: YBL002W
location: 236492..236887
location: region:236492-236887:1
so has part: feature:236492-236887:1:exon

NP_009553.1
type: Protein
SIO_000068: ncbiprotein

S000000098
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:236492-236887:1:exon

YBL001C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ECM15
locus tag: YBL001C
so part of: sequence
location: complement(<237153..>237467)
location: region:237153-237467:-1
so has part: feature:237153-237467:-1:exon
subclass of: SO_0000010

852285
type: Gene
SIO_000068: ncbigene

position:237153:-1
position: 237153
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:237467:-1
position: 237467
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:237153-237467:-1:exon

YBL001C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ECM15
locus tag: YBL001C
product: Ecm15p
transcript id: NM_001178241.1
SIO_010081: YBL001C
subclass of: SO_0000673
so part of: YBL001C
location: complement(<237153..>237467)
location: region:237153-237467:-1
so has part: feature:237153-237467:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:237153-237467:-1:exon

YBL001C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ECM15
locus tag: YBL001C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
note: Non-essential hypothetical protein; likely exists as tetramer, may be regulated by the binding of small-molecule ligands (possibly sulfate ions), may have a role in yeast cell-wall biogenesis
codon start: 1
product: Ecm15p
translation: MPKIFCLADVCMVPIGTDSASISDFVALIEKKIRESPLKSTLHSAGTTIEGPWDDVMGLIGEIHEYGHEKGYVRVHTDIRVGTRTDKHQTAQDKIDVVLKKISQ
SIO_010081: YBL001C
subclass of: SO_0000673
so part of: YBL001C
location: complement(237153..237467)
location: region:237153-237467:-1
so has part: feature:237153-237467:-1:exon

NP_009554.1
type: Protein
SIO_000068: ncbiprotein

S000000097
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:237153-237467:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS208; Autonomously Replicating Sequence
so part of: sequence
location: 237787..237900
location: region:237787-237900:1
so has part: feature:237787-237900:1:region

S000118346
type: SGD
SIO_000068: sgd

position:237787:1
position: 237787
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:237900:1
position: 237900
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:237787-237900:1:region

centromere
type: Centromere
subclass of: SO_0000577
RO_0002162: 559292
note: CEN2; Chromosome II centromere
so part of: sequence
location: 238207..238323
location: region:238207-238323:1
so has part: feature:238207-238323:1:region

S000006464
type: SGD
SIO_000068: sgd

position:238207:1
position: 238207
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:238323:1
position: 238323
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:238207-238323:1:region

centromere
type: Centromere
subclass of: SO_0000577
RO_0002162: 559292
note: CEN2_CDEI of CEN2
so part of: sequence
location: 238207..238216
location: region:238207-238216:1
so has part: feature:238207-238216:1:region

position:238216:1
position: 238216
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:238207-238216:1:region

centromere
type: Centromere
subclass of: SO_0000577
RO_0002162: 559292
note: CEN2_CDEII of CEN2
so part of: sequence
location: 238217..238298
location: region:238217-238298:1
so has part: feature:238217-238298:1:region

position:238217:1
position: 238217
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:238298:1
position: 238298
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:238217-238298:1:region

centromere
type: Centromere
subclass of: SO_0000577
RO_0002162: 559292
note: CEN2_CDEIII of CEN2
so part of: sequence
location: 238299..238323
location: region:238299-238323:1
so has part: feature:238299-238323:1:region

position:238299:1
position: 238299
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:238299-238323:1:region

YBR001C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: NTH2
locus tag: YBR001C
so part of: sequence
location: complement(<238941..>241283)
location: region:238941-241283:-1
so has part: feature:238941-241283:-1:exon
subclass of: SO_0000010

852286
type: Gene
SIO_000068: ncbigene

position:238941:-1
position: 238941
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:241283:-1
position: 241283
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:238941-241283:-1:exon

YBR001C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: NTH2
locus tag: YBR001C
product: alpha,alpha-trehalase NTH2
transcript id: NM_001178349.1
SIO_010081: YBR001C
subclass of: SO_0000673
so part of: YBR001C
location: complement(<238941..>241283)
location: region:238941-241283:-1
so has part: feature:238941-241283:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:238941-241283:-1:exon

YBR001C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: NTH2
locus tag: YBR001C
EC number: 3.2.1.28
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0004555 alpha,alpha-trehalase activity [PMID:18065618]
experiment: EXISTENCE:mutant phenotype:GO:0005993 trehalose catabolic process [PMID:18065618]
note: Putative neutral trehalase, required for thermotolerance; may mediate resistance to other cellular stresses; NTH2 has a paralog, NTH1, that arose from the whole genome duplication
codon start: 1
product: alpha,alpha-trehalase NTH2
translation: MVDFLPKVTEINPPSEGNDGEDNIKPLSSGSEQRPLKEEGQQGGRRHHRRLSSMHEYFDPFSNAEVYYGPITDPRKQSKIHRLNRTRTMSVFNKVSDFKNGMKDYTLKRRGSEDDSFLSSQGNRRFYIDNVDLALDELLASEDTDKNHQITIEDTGPKVIKVGTANSNGFKHVNVRGTYMLSNLLQELTIAKSFGRHQIFLDEARINENPVDRLSRLITTQFWTSLTRRVDLYNIAEIARDSKIDTPGAKNPRIYVPYNCPEQYEFYIQASQMNPSLKLEVEYLPKDITAEYVKSLNDTPGLLALAMEEHVNPSTGERSLVGYPYAVPGGRFNELYGWDSYLMALGLIESNKVDVARGMVEHFIFEIDHYSKILNANRSYYLCRSQPPFLTDMALLVFEKIGGKNNPNAIQLLKRAFRAAIKEYKEVWMSSPRLDSLTGLSCYHSDGIGIPPETEPDHFDTILLPYAEKYNVTLEKLRYLYNEGMIKEPKLDAFFLHDRAVRESGHDTTYRFEGVCAYLATIDLNSLLYKYEKDIAFVIKEYFGNEYKDENDGTVTDSEHWEELAELRKTRINKYMWDEDSGFFFYYNTKLKCRTSYESATTFWSLWAGLATEEQAKITVEKALPQLEMLGGLVACTEKSRGPISIDRPIRQWDYPFGWAPHQILAWKGLSAYGYQQVATRLAYRWLYMITKSFVDYNGMVVEKYDVTRGTDPHRVDAEYGNQGADFKGVATEGFGWVNTSYLLGLKYMNNHARRALAACSPPLPFFNSLKPSEKKLYYL
SIO_010081: YBR001C
subclass of: SO_0000673
so part of: YBR001C
location: complement(238941..241283)
location: region:238941-241283:-1
so has part: feature:238941-241283:-1:exon

NP_009555.1
type: Protein
SIO_000068: ncbiprotein

S000000205
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:238941-241283:-1:exon

YBR002C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RER2
locus tag: YBR002C
so part of: sequence
location: complement(<241708..>242568)
location: region:241708-242568:-1
so has part: feature:241708-242568:-1:exon
subclass of: SO_0000010

852287
type: Gene
SIO_000068: ncbigene

position:241708:-1
position: 241708
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:242568:-1
position: 242568
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:241708-242568:-1:exon

YBR002C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RER2
locus tag: YBR002C
product: ditrans,polycis-polyprenyl diphosphate synthase
transcript id: NM_001178350.1
SIO_010081: YBR002C
subclass of: SO_0000673
so part of: YBR002C
location: complement(<241708..>242568)
location: region:241708-242568:-1
so has part: feature:241708-242568:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:241708-242568:-1:exon

YBR002C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RER2
locus tag: YBR002C
EC number: 2.5.1.87
experiment: EXISTENCE:direct assay:GO:0004659 prenyltransferase activity [PMID:17345630|PMID:9858571]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:11442630|PMID:24868093|PMID:9858571|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005811 lipid droplet [PMID:24868093]
experiment: EXISTENCE:direct assay:GO:0006486 protein glycosylation [PMID:9858571]
experiment: EXISTENCE:direct assay:GO:0019408 dolichol biosynthetic process [PMID:10217761|PMID:25066056]
experiment: EXISTENCE:direct assay:GO:0045547 dehydrodolichyl diphosphate synthase activity [PMID:11442630|PMID:25066056]
experiment: EXISTENCE:direct assay:GO:1904423 dehydrodolichyl diphosphate synthase complex [PMID:25066056]
experiment: EXISTENCE:mutant phenotype:GO:0006486 protein glycosylation [PMID:9858571]
experiment: EXISTENCE:mutant phenotype:GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport [PMID:12911815]
note: Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1; major enzyme of polyprenol synthesis in both the endoplasmic reticulum (ER) and in lipid droplets; participates in ER protein sorting; human ortholog DHDDS functionally complements the heat sensitive growth defect of a ts allele, and is associated with retinitis pigmentosa
codon start: 1
product: ditrans,polycis-polyprenyl diphosphate synthase
translation: METDSGIPGHSFVLKWTKNIFSRTLRASNCVPRHVGFIMDGNRRFARKKEMDVKEGHEAGFVSMSRILELCYEAGVDTATVFAFSIENFKRSSREVESLMTLARERIRQITERGELACKYGVRIKIIGDLSLLDKSLLEDVRVAVETTKNNKRATLNICFPYTGREEILHAMKETIVQHKKGAAIDESTLESHLYTAGVPPLDLLIRTSGVSRLSDFLIWQASSKGVRIELLDCLWPEFGPIRMAWILLKFSFHKSFLNKEYRLEEGDYDEETNGDPIDLKEKKLN
SIO_010081: YBR002C
subclass of: SO_0000673
so part of: YBR002C
location: complement(241708..242568)
location: region:241708-242568:-1
so has part: feature:241708-242568:-1:exon

NP_009556.1
type: Protein
SIO_000068: ncbiprotein

S000000206
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:241708-242568:-1:exon

YBR003W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: COQ1
locus tag: YBR003W
so part of: sequence
location: <242809..>244230
location: region:242809-244230:1
so has part: feature:242809-244230:1:exon
subclass of: SO_0000010

852288
type: Gene
SIO_000068: ncbigene

position:242809:1
position: 242809
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:244230:1
position: 244230
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:242809-244230:1:exon

YBR003W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: COQ1
locus tag: YBR003W
product: trans-hexaprenyltranstransferase
transcript id: NM_001178351.1
SIO_010081: YBR003W
subclass of: SO_0000673
so part of: YBR003W
location: <242809..>244230
location: region:242809-244230:1
so has part: feature:242809-244230:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:242809-244230:1:exon

YBR003W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: COQ1
locus tag: YBR003W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:14576278|PMID:24769239]
experiment: EXISTENCE:mutant phenotype:GO:0000010 trans-hexaprenyltranstransferase activity [PMID:9708911]
experiment: EXISTENCE:mutant phenotype:GO:0005739 mitochondrion [PMID:10760477]
experiment: EXISTENCE:mutant phenotype:GO:0006744 ubiquinone biosynthetic process [PMID:9708911]
note: Hexaprenyl pyrophosphate synthetase; catalyzes the first step in ubiquinone (coenzyme Q) biosynthesis
codon start: 1
product: trans-hexaprenyltranstransferase
translation: MFQRSGAAHHIKLISSRRCRFKSSFAVALNAASKLVTPKILWNNPISLVSKEMNTLAKNIVALIGSGHPVLNKVTSYYFETEGKKVRPLLVLLLSRALSEIPMTERNHLKIDKSDVPEDPIYSKPSQNQLFQRPASSISPLHILHGIKPLNPLTKGPEPLPEETFDKQRGILPKQRRLAEIVEMIHTASLLHDDVIDHSDTRRGRPSGNAAFTNKMAVLAGDFLLGRATVSISRLHNPEVVELMSNSIANLVEGEFMQLKNTSIDADIDTIENGHKLLPVPSKKLEVKEHDFRVPSRQQGLQLSHDQIIETAFEYYIHKTYLKTAALISKSCRCAAILSGASPAVIDECYDFGRNLGICFQLVDDMLDFTVSGKDLGKPSGADLKLGIATAPVLFAWKEDPSLGPLISRNFSERGDVEKTIDSVRLHNGIAKTKILAEEYRDKALQNLRDSLPESDARSALEFLTNSILTRRK
SIO_010081: YBR003W
subclass of: SO_0000673
so part of: YBR003W
location: 242809..244230
location: region:242809-244230:1
so has part: feature:242809-244230:1:exon

NP_009557.1
type: Protein
SIO_000068: ncbiprotein

S000000207
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:242809-244230:1:exon

YBR004C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GPI18
locus tag: YBR004C
so part of: sequence
location: complement(<244366..>245667)
location: region:244366-245667:-1
so has part: feature:244366-245667:-1:exon
subclass of: SO_0000010

852289
type: Gene
SIO_000068: ncbigene

position:244366:-1
position: 244366
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:245667:-1
position: 245667
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:244366-245667:-1:exon

YBR004C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GPI18
locus tag: YBR004C
product: GPI-anchor transamidase GPI18
transcript id: NM_001178352.2
SIO_010081: YBR004C
subclass of: SO_0000673
so part of: YBR004C
location: complement(<244366..>245667)
location: region:244366-245667:-1
so has part: feature:244366-245667:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:244366-245667:-1:exon

YBR004C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GPI18
locus tag: YBR004C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:17615295|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:17615295]
experiment: EXISTENCE:genetic interaction:GO:0000009 alpha-1,6-mannosyltransferase activity [PMID:15720390]
experiment: EXISTENCE:genetic interaction:GO:0000030 mannosyltransferase activity [PMID:15623507]
experiment: EXISTENCE:genetic interaction:GO:0006506 GPI anchor biosynthetic process [PMID:15623507]
experiment: EXISTENCE:genetic interaction:GO:0031501 mannosyltransferase complex [PMID:17615295]
experiment: EXISTENCE:mutant phenotype:GO:0000009 alpha-1,6-mannosyltransferase activity [PMID:15720390]
experiment: EXISTENCE:mutant phenotype:GO:0000030 mannosyltransferase activity [PMID:15720390]
experiment: EXISTENCE:mutant phenotype:GO:0006506 GPI anchor biosynthetic process [PMID:15720390]
experiment: EXISTENCE:physical interaction:GO:0031501 mannosyltransferase complex [PMID:17615295]
note: Functional ortholog of human PIG-V; PIG-V is a mannosyltransferase that transfers the second mannose in glycosylphosphatidylinositol biosynthesis; the authentic, non-tagged protein was localized to mitochondria
codon start: 1
product: GPI-anchor transamidase GPI18
translation: MIVGLTLYFVLFRSIQYLLVFLTPIRQFDTSTSLLLNELCSSPSEINSYWNKYFWNKLLSWDSVFFIKNITSKNGKPQFEHEYAFSQLWTFFVRLFIKSNNDSIYHALRVGVAIENVLFYLSGIVLYFLTKKIFSQNIRQSQFARTIAKKTSLLFFLTSAAGFLTSIYSEPLSFFFAFVGIWSRECSISVPVLGQFDISWRYWFPYSFISMACFTLASLNRSNCVLLGIYFIFDLIELTKNRKFVKAICFPLLSGSLMFSALLYQQYYLPYKTFCPQRGEWCKSQLFSSIFITKTSLYSYIQSHYWGVGLLKYWTPNNIPNFLFAVPNIIILIYSSIYFSKIYPSYNLKALVWITRALVVIVCFFAHVQILNRIASFLPLHLWYLADRLVKTSDPKKMENPKGDDKIVKFYIYWLAFWIPLQTILFAAFLPPA
SIO_010081: YBR004C
subclass of: SO_0000673
so part of: YBR004C
location: complement(244366..245667)
location: region:244366-245667:-1
so has part: feature:244366-245667:-1:exon

NP_009558.2
type: Protein
SIO_000068: ncbiprotein

S000000208
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:244366-245667:-1:exon

YBR005W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SSH6
gene: RCR1
locus tag: YBR005W
gene synonym: SSH6
so part of: sequence
location: <245906..>246547
location: region:245906-246547:1
so has part: feature:245906-246547:1:exon
subclass of: SO_0000010

852290
type: Gene
SIO_000068: ncbigene

position:245906:1
position: 245906
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:246547:1
position: 246547
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:245906-246547:1:exon

YBR005W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SSH6
gene: RCR1
locus tag: YBR005W
gene synonym: SSH6
product: Rcr1p
transcript id: NM_001178353.1
SIO_010081: YBR005W
subclass of: SO_0000673
so part of: YBR005W
location: <245906..>246547
location: region:245906-246547:1
so has part: feature:245906-246547:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:245906-246547:1:exon

YBR005W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SSH6
gene: RCR1
locus tag: YBR005W
gene synonym: SSH6
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:15590673]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:32421152]
experiment: EXISTENCE:direct assay:GO:0043495 protein-membrane adaptor activity [PMID:32421152]
experiment: EXISTENCE:direct assay:GO:0072659 protein localization to plasma membrane [PMID:32421152]
experiment: EXISTENCE:genetic interaction:GO:0016192 vesicle-mediated transport [PMID:17287526]
experiment: EXISTENCE:mutant phenotype:GO:0006033 chitin localization [PMID:15590673]
note: Plasma membrane (PM) ubiquitin ligase-substrate adaptor; involved in cell wall chitin deposition; ubiquitinates and down-regulates chitin synthase Chs3p abundance at PM via calcineurin/Crz1 signaling pathway which regulates RCR1 expression; delivered to PM by exomer complex using novel PM sorting motif; RCR1 has a paralog, RCR2, that arose from the whole genome duplication
codon start: 1
product: Rcr1p
translation: MGLISYENEAINEVKKADNHHVSKFVTSYYGPSSSSWQSGIWILFVLFVAAVILIILFTFVANRRRRRMGRAPIRGTAWLTPPSYRQSQQQYTGTVQQRTDDYVPEYTETANEHDLGYYDQRGEFHPNDKAAYVAPPPLVQECSSESVNSLERPPAAVVHQANSLDTDYGLTRPSNGRVPAVSDTVEQLERLPGGTTTQEINPPERAKVNARS
SIO_010081: YBR005W
subclass of: SO_0000673
so part of: YBR005W
location: 245906..246547
location: region:245906-246547:1
so has part: feature:245906-246547:1:exon

NP_009559.1
type: Protein
SIO_000068: ncbiprotein

S000000209
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:245906-246547:1:exon

YBR006W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: UGA5
gene: UGA2
locus tag: YBR006W
gene synonym: UGA5
so part of: sequence
location: <247010..>248503
location: region:247010-248503:1
so has part: feature:247010-248503:1:exon
subclass of: SO_0000010

852291
type: Gene
SIO_000068: ncbigene

position:247010:1
position: 247010
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:248503:1
position: 248503
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:247010-248503:1:exon

YBR006W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: UGA5
gene: UGA2
locus tag: YBR006W
gene synonym: UGA5
product: succinate-semialdehyde dehydrogenase (NAD(P)(+))
transcript id: NM_001178354.1
SIO_010081: YBR006W
subclass of: SO_0000673
so part of: YBR006W
location: <247010..>248503
location: region:247010-248503:1
so has part: feature:247010-248503:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:247010-248503:1:exon

YBR006W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: UGA5
gene: UGA2
locus tag: YBR006W
gene synonym: UGA5
EC number: 1.2.1.16
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:genetic interaction:GO:0006540 glutamate decarboxylation to succinate [PMID:11031268]
experiment: EXISTENCE:mutant phenotype:GO:0006540 glutamate decarboxylation to succinate [PMID:11031268]
experiment: EXISTENCE:mutant phenotype:GO:0009013 succinate-semialdehyde dehydrogenase [NAD(P)+] activity [PMID:11031268|PMID:3888627]
experiment: EXISTENCE:mutant phenotype:GO:0009450 gamma-aminobutyric acid catabolic process [PMID:11031268|PMID:3888627]
experiment: EXISTENCE:mutant phenotype:GO:0034599 cellular response to oxidative stress [PMID:11031268]
note: Succinate semialdehyde dehydrogenase; involved in the utilization of gamma-aminobutyrate (GABA) as a nitrogen source; part of the 4-aminobutyrate and glutamate degradation pathways; localized to the cytoplasm
codon start: 1
product: succinate-semialdehyde dehydrogenase (NAD(P)(+))
translation: MTLSKYSKPTLNDPNLFRESGYIDGKWVKGTDEVFEVVDPASGEIIARVPEQPVSVVEEAIDVAYETFKTYKNTTPRERAKWLRNMYNLMLENLDDLATIITLENGKALGEAKGEIKYAASYFEWYAEEAPRLYGATIQPLNPHNRVFTIRQPVGVCGIICPWNFPSAMITRKAAAALAVGCTVVIKPDSQTPLSALAMAYLAEKAGFPKGSFNVILSHANTPKLGKTLCESPKVKKVTFTGSTNVGKILMKQSSSTLKKLSFELGGNAPFIVFEDADLDQALEQAMACKFRGLGQTCVCANRLYVHSSIIDKFAKLLAERVKKFVIGHGLDPKTTHGCVINSSAIEKVERHKQDAIDKGAKVVLEGGRLTELGPNFYAPVILSHVPSTAIVSKEETFGPLCPIFSFDTMEEVVGYANDTEFGLAAYVFSKNVNTLYTVSEALETGMVSCNTGVFSDCSIPFGGVKESGFGREGSLYGIEDYTVLKTITIGNLPNSI
SIO_010081: YBR006W
subclass of: SO_0000673
so part of: YBR006W
location: 247010..248503
location: region:247010-248503:1
so has part: feature:247010-248503:1:exon

NP_009560.1
type: Protein
SIO_000068: ncbiprotein

S000000210
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:247010-248503:1:exon

YBR007C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: DSF2
locus tag: YBR007C
so part of: sequence
location: complement(<248806..>251016)
location: region:248806-251016:-1
so has part: feature:248806-251016:-1:exon
subclass of: SO_0000010

852292
type: Gene
SIO_000068: ncbigene

position:248806:-1
position: 248806
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:251016:-1
position: 251016
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:248806-251016:-1:exon

YBR007C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: DSF2
locus tag: YBR007C
product: Dsf2p
transcript id: NM_001178355.2
SIO_010081: YBR007C
subclass of: SO_0000673
so part of: YBR007C
location: complement(<248806..>251016)
location: region:248806-251016:-1
so has part: feature:248806-251016:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:248806-251016:-1:exon

YBR007C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: DSF2
locus tag: YBR007C
experiment: EXISTENCE:direct assay:GO:0005934 cellular bud tip [PMID:22842922]
note: Deletion suppressor of mpt5 mutation; relocalizes from bud neck to cytoplasm upon DNA replication stress
codon start: 1
product: Dsf2p
translation: MNQNLKNTSWADRIGSDDQERKANSSEVSQSPPPNNSFESSMDSQFSYAHSNKSSISFESIQTTERLLDKLDLSLEDELILQEALLEEENASRNSQLSQTSGPTLCMPASEFPSLRYRTNPSPTYIQARDRSLIIDNLKEKDSTLRGKYSSGKVERHLPVKSRYSYIVEEDYDSETFSGMKPQMNRNEKDYKYPNLENGNRSTNSPNPFNFEKYRIENTRLHHLYPTLISDNNTSVDNNANSKNNRTTSNNINTSTKTDRISEKQSCPNEFTTTQKSNCLYRNGSSTSTNTSFSEVGQLSKPKTQSSFESESSSFSKLKLTKSDTTPIKPSPKRSNSSTSTITKTNTMTNDISLPPTPPYKAHKKKTSLNSLKKLFKSPRTRAKNKKDLESEGSSPIRSATNSLDFSGENIQLPSTSSTINNSSPHLARYIFPPNPVFHFKTASTPQSSTDKKKNSKARPNRTHLRTFSDFHTTEKDSKIGELSALTEQSNKPYHPKVRRRTLSLDGMLPNNSTQCMDSFSHKKEGSNATSKCGKLKFHPEPYDNDESSHIGQAITMRHQGKLEESAQRLKKACACGNKTAFLLYGLALRHGCGVDKNLKLSLGYLMAATDIKSFAAEVLDLDINPLNFASMDDIPDIAPEPTAPALYECGMAYLKGLGMDHPDERKGLKFLEKAALLGHVDSMCLSGTIWSKTSNVKKRDLARAAAWFRIADKKGANLLGSDWIYKEKYMKQGPK
SIO_010081: YBR007C
subclass of: SO_0000673
so part of: YBR007C
location: complement(248806..251016)
location: region:248806-251016:-1
so has part: feature:248806-251016:-1:exon

NP_009561.2
type: Protein
SIO_000068: ncbiprotein

S000000211
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:248806-251016:-1:exon

YBR008C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FLR1
locus tag: YBR008C
so part of: sequence
location: complement(<252563..>254209)
location: region:252563-254209:-1
so has part: feature:252563-254209:-1:exon
subclass of: SO_0000010

852293
type: Gene
SIO_000068: ncbigene

position:252563:-1
position: 252563
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:254209:-1
position: 254209
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:252563-254209:-1:exon

YBR008C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FLR1
locus tag: YBR008C
product: Flr1p
transcript id: NM_001178356.1
SIO_010081: YBR008C
subclass of: SO_0000673
so part of: YBR008C
location: complement(<252563..>254209)
location: region:252563-254209:-1
so has part: feature:252563-254209:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:252563-254209:-1:exon

YBR008C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FLR1
locus tag: YBR008C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:10903515]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:1990961 xenobiotic detoxification by transmembrane export across the plasma membrane [PMID:10572257|PMID:9235926]
experiment: EXISTENCE:mutant phenotype:GO:0015244 fluconazole transmembrane transporter activity [PMID:9235926]
experiment: EXISTENCE:mutant phenotype:GO:1990961 xenobiotic detoxification by transmembrane export across the plasma membrane [PMID:10572257]
note: Plasma membrane transporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; involved in efflux of fluconazole, diazaborine, benomyl, methotrexate, and other drugs; expression induced in cells treated with the mycotoxin patulin; relocalizes from nucleus to plasma membrane upon DNA replication stress
codon start: 1
product: Flr1p
translation: MVYTSTYRHTIVVDLLEYLGIVSNLETLQSAREDETRKPENTDKKECKPDYDIECGPNRSCSESSTDSDSSGSQIEKNDPFRVDWNGPSDPENPQNWPLLKKSLVVFQIMLLTCVTYMGSSIYTPGQEYIQEEFHVGHVVATLNLSLYVLGYGLGPIIFSPLSETARYGRLNLYMVTLFFFMIFQVGCATVHNIGGLIVMRFISGILCSPSLATGGGTVADIISPEMVPLVLGMWSAGAVAAPVLAPLLGAAMVDAKNWRFIFWLLMWLSAATFILLAFFFPETQHHNILYRRALKLRKETGDDRYYTEQDKLDREVDARTFLINTLYRPLKMIIKEPAILAFDLYIAVAYGCFYLFFEAFPIVFVGIYHFSLVEVGLAYMGFCVGCVLAYGLFGILNMRIIVPRFRNGTFTPEAFLIVAMCVCWCLPLSLFLFGWTARVHWILPVISEVFFVLAVFNIFQATFAYLATCYPKYVASVFAGNGFCRASFACAFPLFGRAMYDNLATKNYPVAWGSSLVGFLTLGLAIIPFILYKYGPSLRTRSSYTEE
SIO_010081: YBR008C
subclass of: SO_0000673
so part of: YBR008C
location: complement(252563..254209)
location: region:252563-254209:-1
so has part: feature:252563-254209:-1:exon

NP_009562.1
type: Protein
SIO_000068: ncbiprotein

S000000212
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:252563-254209:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS209; Autonomously Replicating Sequence; originally referred to as H4 ARS
so part of: sequence
location: 254998..255083
location: region:254998-255083:1
so has part: feature:254998-255083:1:region

S000114517
type: SGD
SIO_000068: sgd

position:254998:1
position: 254998
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:255083:1
position: 255083
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:254998-255083:1:region

YBR009C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HHF1
locus tag: YBR009C
so part of: sequence
location: complement(<255373..>255684)
location: region:255373-255684:-1
so has part: feature:255373-255684:-1:exon
subclass of: SO_0000010

852294
type: Gene
SIO_000068: ncbigene

position:255373:-1
position: 255373
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:255684:-1
position: 255684
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:255373-255684:-1:exon

YBR009C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HHF1
locus tag: YBR009C
product: histone H4
transcript id: NM_001178357.1
SIO_010081: YBR009C
subclass of: SO_0000673
so part of: YBR009C
location: complement(<255373..>255684)
location: region:255373-255684:-1
so has part: feature:255373-255684:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:255373-255684:-1:exon

YBR009C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: HHF1
locus tag: YBR009C
experiment: EXISTENCE:direct assay:GO:0031298 replication fork protection complex [PMID:16531994]
note: Histone H4; core histone protein required for chromatin assembly and chromosome function; one of two identical histone proteins (see also HHF2); contributes to telomeric silencing; involved in mRNA multiplexing; N-terminal domain involved in maintaining genomic integrity
codon start: 1
product: histone H4
translation: MSGRGKGGKGLGKGGAKRHRKILRDNIQGITKPAIRRLARRGGVKRISGLIYEEVRAVLKSFLESVIRDSVTYTEHAKRKTVTSLDVVYALKRQGRTLYGFGG
SIO_010081: YBR009C
subclass of: SO_0000673
so part of: YBR009C
location: complement(255373..255684)
location: region:255373-255684:-1
so has part: feature:255373-255684:-1:exon

NP_009563.1
type: Protein
SIO_000068: ncbiprotein

S000000213
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:255373-255684:-1:exon

YBR010W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: BUR5
alternative label: SIN2
gene: HHT1
locus tag: YBR010W
gene synonym: BUR5; SIN2
so part of: sequence
location: <256331..>256741
location: region:256331-256741:1
so has part: feature:256331-256741:1:exon
subclass of: SO_0000010

852295
type: Gene
SIO_000068: ncbigene

position:256331:1
position: 256331
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:256741:1
position: 256741
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:256331-256741:1:exon

YBR010W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: BUR5
alternative label: SIN2
gene: HHT1
locus tag: YBR010W
gene synonym: BUR5; SIN2
product: histone H3
transcript id: NM_001178358.1
SIO_010081: YBR010W
subclass of: SO_0000673
so part of: YBR010W
location: <256331..>256741
location: region:256331-256741:1
so has part: feature:256331-256741:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:256331-256741:1:exon

YBR010W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: BUR5
alternative label: SIN2
gene: HHT1
locus tag: YBR010W
gene synonym: BUR5; SIN2
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0008823 cupric reductase activity [PMID:32631887]
experiment: EXISTENCE:direct assay:GO:0031298 replication fork protection complex [PMID:16531994]
experiment: EXISTENCE:direct assay:GO:0043505 CENP-A containing nucleosome [PMID:22693454]
experiment: EXISTENCE:mutant phenotype:GO:0006878 cellular copper ion homeostasis [PMID:32631887]
experiment: EXISTENCE:mutant phenotype:GO:0008823 cupric reductase activity [PMID:32631887]
experiment: EXISTENCE:mutant phenotype:GO:0009060 aerobic respiration [PMID:32631887]
experiment: EXISTENCE:mutant phenotype:GO:0009303 rRNA transcription [PMID:16002464]
experiment: EXISTENCE:mutant phenotype:GO:0043935 sexual sporulation resulting in formation of a cellular spore [PMID:20713519]
experiment: EXISTENCE:mutant phenotype:GO:0070911 global genome nucleotide-excision repair [PMID:21460225]
note: Histone H3; core histone protein required for chromatin assembly, part of heterochromatin-mediated telomeric and HM silencing; one of two identical histone H3 proteins (see HHT2); regulated by acetylation, methylation, and phosphorylation; H3K14 acetylation plays an important role in the unfolding of strongly positioned nucleosomes during repair of UV damage
codon start: 1
product: histone H3
translation: MARTKQTARKSTGGKAPRKQLASKAARKSAPSTGGVKKPHRYKPGTVALREIRRFQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAIGALQESVEAYLVSLFEDTNLAAIHAKRVTIQKKDIKLARRLRGERS
SIO_010081: YBR010W
subclass of: SO_0000673
so part of: YBR010W
location: 256331..256741
location: region:256331-256741:1
so has part: feature:256331-256741:1:exon

NP_009564.1
type: Protein
SIO_000068: ncbiprotein

S000000214
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:256331-256741:1:exon

YBR011C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PPA1
gene: IPP1
locus tag: YBR011C
gene synonym: PPA1
so part of: sequence
location: complement(<257112..>257975)
location: region:257112-257975:-1
so has part: feature:257112-257975:-1:exon
subclass of: SO_0000010

852296
type: Gene
SIO_000068: ncbigene

position:257112:-1
position: 257112
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:257975:-1
position: 257975
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:257112-257975:-1:exon

YBR011C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PPA1
gene: IPP1
locus tag: YBR011C
gene synonym: PPA1
product: inorganic diphosphatase IPP1
transcript id: NM_001178359.1
SIO_010081: YBR011C
subclass of: SO_0000673
so part of: YBR011C
location: complement(<257112..>257975)
location: region:257112-257975:-1
so has part: feature:257112-257975:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:257112-257975:-1:exon

YBR011C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PPA1
gene: IPP1
locus tag: YBR011C
gene synonym: PPA1
EC number: 3.6.1.1
experiment: EXISTENCE:curator inference:GO:0006796 phosphate-containing compound metabolic process [PMID:8224193]
experiment: EXISTENCE:direct assay:GO:0004427 inorganic diphosphate phosphatase activity [PMID:8224193]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
note: Cytoplasmic inorganic pyrophosphatase (PPase); homodimer that catalyzes the rapid exchange of oxygens from Pi with water, highly expressed and essential for viability, active-site residues show identity to those from E. coli PPase
codon start: 1
product: inorganic diphosphatase IPP1
translation: MTYTTRQIGAKNTLEYKVYIEKDGKPVSAFHDIPLYADKENNIFNMVVEIPRWTNAKLEITKEETLNPIIQDTKKGKLRFVRNCFPHHGYIHNYGAFPQTWEDPNVSHPETKAVGDNDPIDVLEIGETIAYTGQVKQVKALGIMALLDEGETDWKVIAIDINDPLAPKLNDIEDVEKYFPGLLRATNEWFRIYKIPDGKPENQFAFSGEAKNKKYALDIIKETHDSWKQLIAGKSSDSKGIDLTNVTLPDTPTYSKAASDAIPPASPKADAPIDKSIDKWFFISGSV
SIO_010081: YBR011C
subclass of: SO_0000673
so part of: YBR011C
location: complement(257112..257975)
location: region:257112-257975:-1
so has part: feature:257112-257975:-1:exon

NP_009565.1
type: Protein
SIO_000068: ncbiprotein

S000000215
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:257112-257975:-1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(258670..258976)
location: region:258670-258976:-1
so has part: feature:258670-258976:-1:region

S000006810
type: SGD
SIO_000068: sgd

position:258670:-1
position: 258670
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:258976:-1
position: 258976
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:258670-258976:-1:region

mobile_element
type: Mobile Element
subclass of: SO_0001037
RO_0002162: 559292
note: YBRWTy1-2; Ty1 element, LTR retrotransposon of the Copia (Pseudoviridae) group; contains co-transcribed genes TYA Gag and TYB Pol, encoding proteins involved in structure and function of virus-like particles, flanked by two direct repeats
mobile element type: retrotransposon:YBRWTy1-2
so part of: sequence
location: 259578..265494
location: region:259578-265494:1
so has part: feature:259578-265494:1:region

S000006821
type: SGD
SIO_000068: sgd

position:259578:1
position: 259578
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:265494:1
position: 265494
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:259578-265494:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 259578..259909
location: region:259578-259909:1
so has part: feature:259578-259909:1:region

S000006815
type: SGD
SIO_000068: sgd

position:259909:1
position: 259909
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:259578-259909:1:region

YBR012W-B
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBR012W-B
so part of: sequence
location: <259869..>265140
location: region:259869-265140:1
so has part: feature:259869-265140:1:exon
subclass of: SO_0000010

852299
type: Gene
SIO_000068: ncbigene

position:259869:1
position: 259869
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:265140:1
position: 265140
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:259869-265140:1:exon

YBR012W-B
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBR012W-B
product: gag-pol fusion protein
transcript id: NM_001180056.2
SIO_010081: YBR012W-B
subclass of: SO_0000673
so part of: YBR012W-B
location: <259869..>265140
location: region:259869-265140:1
so has part: feature:259869-265140:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:259869-265140:1:exon

YBR012W-B
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBR012W-B
EC number: 2.7.7.7
EC number: 2.7.7.49
EC number: 3.1.26.4
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:9448009]
ribosomal slippage: true
note: Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes
codon start: 1
product: gag-pol fusion protein
translation: MESQQLSNYPHISHGSACASVTSKEVHTNQDPLDVSASKIQEYDKASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRPITDDELTFLYNAFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQKLTESTVNHTNHSDDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQDNTKTSLKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWVSKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNESDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKSAPSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSEYTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFSAIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKDSRLDQFNYDALTFDEDLNRLTASYQSFIASNEIQQSNDLNIESDHDFQSDIELYPEQPRNVLSKAVSPTDSTPPSTHTEDSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISDIESTDSGGMHRLDVPLLAPMSQSNTHESSYASKSKDFRHSDSYSDNETNHTNVPISSTGGTNNKTVPQTSEQETEKRIIHRFTSDRILPSSESNSLHHVVPIKTSDTCFKENTEESIIADLPLPDLPPEPPTELSDSFKELPPINSRQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSLEPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLLKMKTWDTDKYYDRKEIDPKRVINSMFIFNRKRDGTHKARFVARGDIQHPDTYDSGMQSNTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLKKSLYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKDLNSNKRIIAKLKMQYDTKIINLGESDDEIQHDILGLEIKYQRGKYMKLGMENSLTEKIPKLNVPLNPNGRKLGAPGQPGLYINQQELELEEDDYKMKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSKQVLDMTYELIQFIWNTRDKQLIWHKSKPVKPTNKLVVISDASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSYLIQELDKKPITKGLLTDSKSTISIIISNNEEKFRNRFFGTKAMRLRDEVSGNHLHVCYIETKKNIADVMTKPLPIKTFKLLTNKWIH
SIO_010081: YBR012W-B
subclass of: SO_0000673
so part of: YBR012W-B
location: join(259869..261173,261175..265140)
location: region:259869-265140:1
so has part: feature:259869-261173:1:exon
so has part: feature:261175-265140:1:exon

NP_009567.1
type: Protein
SIO_000068: ncbiprotein

S000002155
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:259869-261173:1:exon

position:261173:1
position: 261173
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:261175-265140:1:exon

position:261175:1
position: 261175
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YBR012W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBR012W-A
so part of: sequence
location: <259869..>261191
location: region:259869-261191:1
so has part: feature:259869-261191:1:exon
subclass of: SO_0000010

852298
type: Gene
SIO_000068: ncbigene

position:261191:1
position: 261191
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:259869-261191:1:exon

YBR012W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBR012W-A
product: gag protein
transcript id: NM_001180055.1
SIO_010081: YBR012W-A
subclass of: SO_0000673
so part of: YBR012W-A
location: <259869..>261191
location: region:259869-261191:1
so has part: feature:259869-261191:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:259869-261191:1:exon

YBR012W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBR012W-A
note: Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag
codon start: 1
product: gag protein
translation: MESQQLSNYPHISHGSACASVTSKEVHTNQDPLDVSASKIQEYDKASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRPITDDELTFLYNAFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPETY
SIO_010081: YBR012W-A
subclass of: SO_0000673
so part of: YBR012W-A
location: 259869..261191
location: region:259869-261191:1
so has part: feature:259869-261191:1:exon

NP_009568.1
type: Protein
SIO_000068: ncbiprotein

S000002154
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:259869-261191:1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 265163..265494
location: region:265163-265494:1
so has part: feature:265163-265494:1:region

S000006816
type: SGD
SIO_000068: sgd

position:265163:1
position: 265163
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:265163-265494:1:region

YBR013C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBR013C
so part of: sequence
location: complement(<265492..>265881)
location: region:265492-265881:-1
so has part: feature:265492-265881:-1:exon
subclass of: SO_0000010

852300
type: Gene
SIO_000068: ncbigene

position:265492:-1
position: 265492
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:265881:-1
position: 265881
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:265492-265881:-1:exon

YBR013C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBR013C
product: uncharacterized protein
transcript id: NM_001178361.1
SIO_010081: YBR013C
subclass of: SO_0000673
so part of: YBR013C
location: complement(<265492..>265881)
location: region:265492-265881:-1
so has part: feature:265492-265881:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:265492-265881:-1:exon

YBR013C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBR013C
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
note: hypothetical protein; haploid deletion mutant exhibits synthetic phenotype with alpha-synuclein; SWAT-GFP fusion protein localizes to the endoplasmic reticulum while mCherry fusion protein localizes to both the endoplasmic reticulum and vacuole
codon start: 1
product: uncharacterized protein
translation: MIYPLFRICILGAFLLGSYACLENSTQKGIEGVTLSHNSVQINNTLAKSAPFCESDALSMNYSTENMLSNNACDYTKNSSYPYIITIITKAFDNALENSLNLQANRKLYHRVGTCIQNIFYQLLLTVNY
SIO_010081: YBR013C
subclass of: SO_0000673
so part of: YBR013C
location: complement(265492..265881)
location: region:265492-265881:-1
so has part: feature:265492-265881:-1:exon

NP_009569.1
type: Protein
SIO_000068: ncbiprotein

S000000217
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:265492-265881:-1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(266178..266256)
location: region:266178-266256:-1
so has part: feature:266178-266256:-1:region

S000006811
type: SGD
SIO_000068: sgd

position:266178:-1
position: 266178
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:266256:-1
position: 266256
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:266178-266256:-1:region

YNCB0007W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCB0007W
so part of: sequence
location: 266378..266450
location: region:266378-266450:1
so has part: feature:266378-266450:1:exon
subclass of: SO_0000663

852301
type: Gene
SIO_000068: ncbigene

position:266378:1
position: 266378
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:266450:1
position: 266450
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:266378-266450:1:exon

YNCB0007W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCB0007W
product: tRNA-Thr
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Threonine tRNA (tRNA-Thr), predicted by tRNAscan-SE analysis
SIO_010081: YNCB0007W
subclass of: SO_0000673
so part of: YNCB0007W
location: 266378..266450
location: region:266378-266450:1
so has part: feature:266378-266450:1:exon

S000006737
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:266378-266450:1:exon

YBR014C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GRX7
locus tag: YBR014C
so part of: sequence
location: complement(<266725..>267336)
location: region:266725-267336:-1
so has part: feature:266725-267336:-1:exon
subclass of: SO_0000010

852302
type: Gene
SIO_000068: ncbigene

position:266725:-1
position: 266725
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:267336:-1
position: 267336
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:266725-267336:-1:exon

YBR014C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GRX7
locus tag: YBR014C
product: glutathione-disulfide reductase GRX7
transcript id: NM_001178362.1
SIO_010081: YBR014C
subclass of: SO_0000673
so part of: YBR014C
location: complement(<266725..>267336)
location: region:266725-267336:-1
so has part: feature:266725-267336:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:266725-267336:-1:exon

YBR014C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GRX7
locus tag: YBR014C
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0004362 glutathione-disulfide reductase (NADPH) activity [PMID:18400945]
experiment: EXISTENCE:direct assay:GO:0005794 Golgi apparatus [PMID:18503006]
experiment: EXISTENCE:direct assay:GO:0005796 Golgi lumen [PMID:18400945]
experiment: EXISTENCE:direct assay:GO:0005801 cis-Golgi network [PMID:18400945]
experiment: EXISTENCE:direct assay:GO:0016020 membrane [PMID:18503006]
experiment: EXISTENCE:genetic interaction:GO:0034599 cellular response to oxidative stress [PMID:18400945]
note: Cis-golgi localized monothiol glutaredoxin; more similar in activity to dithiol than other monothiol glutaredoxins; involved in the oxidative stress response; does not bind metal ions; GRX7 has a paralog, GRX6, that arose from the whole genome duplication
codon start: 1
product: glutathione-disulfide reductase GRX7
translation: MAIVINKRNVRVLVITNLLLIVVFFVLRNSNASVNESITTHHPDSLVTFDNSGNAPGTHQSVHDTVNTQDKEAEEVDKNSGDAEFDAAAEYNKIMEQSPMIVFSKTGCPYSKKLKALLTNSYTFSPSYYVVELDRHEHTKELQDQIEKVTGRRTVPNVIIGGTSRGGYTEIAELHKNDELLDSFKKWSDGAFTVKANSQSESA
SIO_010081: YBR014C
subclass of: SO_0000673
so part of: YBR014C
location: complement(266725..267336)
location: region:266725-267336:-1
so has part: feature:266725-267336:-1:exon

NP_009570.1
type: Protein
SIO_000068: ncbiprotein

S000000218
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:266725-267336:-1:exon

YBR015C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CRV4
alternative label: LDB8
alternative label: TTP1
gene: MNN2
locus tag: YBR015C
gene synonym: CRV4; LDB8; TTP1
so part of: sequence
location: complement(<267710..>269503)
location: region:267710-269503:-1
so has part: feature:267710-269503:-1:exon
subclass of: SO_0000010

852303
type: Gene
SIO_000068: ncbigene

position:267710:-1
position: 267710
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:269503:-1
position: 269503
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:267710-269503:-1:exon

YBR015C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CRV4
alternative label: LDB8
alternative label: TTP1
gene: MNN2
locus tag: YBR015C
gene synonym: CRV4; LDB8; TTP1
product: alpha-1,2-mannosyltransferase MNN2
transcript id: NM_001178363.1
SIO_010081: YBR015C
subclass of: SO_0000673
so part of: YBR015C
location: complement(<267710..>269503)
location: region:267710-269503:-1
so has part: feature:267710-269503:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:267710-269503:-1:exon

YBR015C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CRV4
alternative label: LDB8
alternative label: TTP1
gene: MNN2
locus tag: YBR015C
gene synonym: CRV4; LDB8; TTP1
experiment: EXISTENCE:direct assay:GO:0005794 Golgi apparatus [PMID:9756928]
experiment: EXISTENCE:mutant phenotype:GO:0000026 alpha-1,2-mannosyltransferase activity [PMID:9756928]
experiment: EXISTENCE:mutant phenotype:GO:0006486 protein glycosylation [PMID:9756928]
note: Alpha-1,2-mannosyltransferase; responsible for addition of the first alpha-1,2-linked mannose to form the branches on the mannan backbone of oligosaccharides, localizes to an early Golgi compartment
codon start: 1
product: alpha-1,2-mannosyltransferase MNN2
translation: MLLTKRFSKLFKLTFIVLILCGLFVITNKYMDENTSVKEYKEYLDRYVQSYSNKYSSSSDAASADDSTPLRDNDEAGNEKLKSFYNNVFNFLMVDSPKGSTAKQYNEACLLKGDIGDRPDHYKDLYKLSAKELSKCLELSPDEVASLTKSHKDYVEHIATLVSPKGTYKGSGIATVGGGKFSLMAFLIIKTLRNMGTTLPVEVLIPPGDEGETEFCNKILPKYNSKCIYVSDILPRETIEKFVFKGYQFKSLALIASSFENLLLLDADNFPIKPLDNIFNEEPYVSTGLVMWPDFWRRTTHPLYYDIAGIAVDKKKRVRNSRDDITPPAVYTKDLKDLSDVPLSDLDGTIPDVSTESGQLMINKTKHLATALLSLFYNVNGPTWYYPIFSQKAAGEGDKETFIAAANFYGLSFYQVRTRTGVEGYHDEDGFHGVAMLQHDFVQDYGRYLNAMESIGNKYGGTKSADAIKFDKNYSLEKYTEEFFDNEDLNAKNHVDVMFIHSNFPKFDPYDLSKSNFLTTNGKPARSYTALKKVKNYDIELENFKVLNEYVCVNKNPFKYLDDLLGQDKTEWKRVCGYITDRLAFLESTHDKAIAGK
SIO_010081: YBR015C
subclass of: SO_0000673
so part of: YBR015C
location: complement(267710..269503)
location: region:267710-269503:-1
so has part: feature:267710-269503:-1:exon

NP_009571.1
type: Protein
SIO_000068: ncbiprotein

S000000219
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:267710-269503:-1:exon

YBR016W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBR016W
so part of: sequence
location: <270247..>270633
location: region:270247-270633:1
so has part: feature:270247-270633:1:exon
subclass of: SO_0000010

852304
type: Gene
SIO_000068: ncbigene

position:270247:1
position: 270247
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:270633:1
position: 270633
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:270247-270633:1:exon

YBR016W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBR016W
product: uncharacterized protein
transcript id: NM_001178364.1
SIO_010081: YBR016W
subclass of: SO_0000673
so part of: YBR016W
location: <270247..>270633
location: region:270247-270633:1
so has part: feature:270247-270633:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:270247-270633:1:exon

YBR016W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBR016W
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:12514182]
experiment: EXISTENCE:direct assay:GO:0033101 cellular bud membrane [PMID:12514182]
experiment: EXISTENCE:direct assay:GO:0070250 mating projection membrane [PMID:12514182]
note: Tail-anchored plasma membrane protein with a conserved CYSTM module; predicted to be palmitoylated; has similarity to hydrophilins, which are involved in the adaptive response to hyperosmotic conditions; YBR016W has a paralog, YDL012C, that arose from the whole genome duplication
codon start: 1
product: uncharacterized protein
translation: MSANDYYGGTAGEKSQYSRPSNPPPSSAHQNKTQERGYPPQQQQQYYQQQQQHPGYYNQQGYNQQGYNQQGYNQQGYNQQGYNQQGYNQQGHQQPVYVQQQPPQRGNEGCLAACLAALCICCTMDMLF
SIO_010081: YBR016W
subclass of: SO_0000673
so part of: YBR016W
location: 270247..270633
location: region:270247-270633:1
so has part: feature:270247-270633:1:exon

NP_009572.1
type: Protein
SIO_000068: ncbiprotein

S000000220
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:270247-270633:1:exon

YBR017C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: KAP104
locus tag: YBR017C
so part of: sequence
location: complement(<270947..>273703)
location: region:270947-273703:-1
so has part: feature:270947-273703:-1:exon
subclass of: SO_0000010

852305
type: Gene
SIO_000068: ncbigene

position:270947:-1
position: 270947
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:273703:-1
position: 273703
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:270947-273703:-1:exon

YBR017C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: KAP104
locus tag: YBR017C
product: Kap104p
transcript id: NM_001178365.1
SIO_010081: YBR017C
subclass of: SO_0000673
so part of: YBR017C
location: complement(<270947..>273703)
location: region:270947-273703:-1
so has part: feature:270947-273703:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:270947-273703:-1:exon

YBR017C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: KAP104
locus tag: YBR017C
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:8849456]
experiment: EXISTENCE:direct assay:GO:0005934 cellular bud tip [PMID:19198597]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:19198597]
experiment: EXISTENCE:direct assay:GO:0006606 protein import into nucleus [PMID:19366694|PMID:8849456|PMID:9488461]
experiment: EXISTENCE:direct assay:GO:0008139 nuclear localization sequence binding [PMID:9488461]
experiment: EXISTENCE:mutant phenotype:GO:0006606 protein import into nucleus [PMID:19366694|PMID:8849456]
experiment: EXISTENCE:mutant phenotype:GO:0010458 exit from mitosis [PMID:12524331]
note: Transportin or cytosolic karyopherin beta 2; functions in the rg-nuclear localization signal-mediated nuclear import/reimport of mRNA-binding proteins Nab2p and Hrp1p; regulates asymmetric protein synthesis in daughter cells during mitosis
codon start: 1
product: Kap104p
translation: MASTWKPAEDYVLQLATLLQNCMSPNPEIRNNAMEAMENFQLQPEFLNYLCYILIEGESDDVLKQHYSLQDLQNNRATAGMLLKNSMLGGNNLIKSNSHDLGYVKSNIIHGLYNSNNNLVSNVTGIVITTLFSTYYRQHRDDPTGLQMLYQLLELTSNGNEPSIKALSKIMEDSAQFFQLEWSGNTKPMEALLDSFFRFISNPNFSPVIRSESVKCINTVIPLQTQSFIVRLDKFLEIIFQLAQNDENDLVRAQICISFSFLLEFRPDKLVSHLDGIVQFMLHLITTVNEEKVAIEACEFLHAFATSPNIPEHILQPYVKDIVPILLSKMVYNEESIVLLEASNDDDAFLEDKDEDIKPIAPRIVKKKEAGNGEDADDNEDDDDDDDDEDGDVDTQWNLRKCSAATLDVMTNILPHQVMDIAFPFLREHLGSDRWFIREATILALGAMAEGGMKYFNDGLPALIPFLVEQLNDKWAPVRKMTCWTLSRFSPWILQDHTEFLIPVLEPIINTLMDKKKDVQEAAISSVAVFIENADSELVETLFYSQLLTSFDKCLKYYKKKNLIILYDAIGRFAEKCALDETAMQIILPPLIEKWALLSDSDKELWPLLECLSCVASSLGERFMPMAPEVYNRAFRILCHCVELEAKSHQDPTIVVPEKDFIITSLDLIDGLVQGLGAHSQDLLFPQGTKDLTILKIMLECLQDPVHEVRQSCFALLGDIVYFFNSELVIGNLEDFLKLIGTEIMHNDDSDGTPAVINAIWALGLISERIDLNTYIIDMSRIILDLFTTNTQIVDSSVMENLSVTIGKMGLTHPEVFSSGAFANDSNWNKWCLSVNALDDVEEKSSAYMGFLKIINLTSTEVTMSNDTIHKIVTGLSSNVEANVFAQEIYTFLMNHSAQISAINFTPDEISFLQQFTS
SIO_010081: YBR017C
subclass of: SO_0000673
so part of: YBR017C
location: complement(270947..273703)
location: region:270947-273703:-1
so has part: feature:270947-273703:-1:exon

NP_009573.1
type: Protein
SIO_000068: ncbiprotein

S000000221
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:270947-273703:-1:exon

YBR018C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GAL7
locus tag: YBR018C
so part of: sequence
location: complement(<274427..>275527)
location: region:274427-275527:-1
so has part: feature:274427-275527:-1:exon
subclass of: SO_0000010

852306
type: Gene
SIO_000068: ncbigene

position:274427:-1
position: 274427
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:275527:-1
position: 275527
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:274427-275527:-1:exon

YBR018C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GAL7
locus tag: YBR018C
product: UDP-glucose:hexose-1-phosphate uridylyltransferase
transcript id: NM_001178366.1
SIO_010081: YBR018C
subclass of: SO_0000673
so part of: YBR018C
location: complement(<274427..>275527)
location: region:274427-275527:-1
so has part: feature:274427-275527:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:274427-275527:-1:exon

YBR018C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GAL7
locus tag: YBR018C
EC number: 2.7.7.12
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:10993714]
experiment: EXISTENCE:direct assay:GO:0008108 UDP-glucose:hexose-1-phosphate uridylyltransferase activity [PMID:387754]
experiment: EXISTENCE:direct assay:GO:0033499 galactose catabolic process via UDP-galactose [PMID:387754]
experiment: EXISTENCE:mutant phenotype:GO:0008108 UDP-glucose:hexose-1-phosphate uridylyltransferase activity [PMID:14158615]
experiment: EXISTENCE:mutant phenotype:GO:0033499 galactose catabolic process via UDP-galactose [PMID:14158615]
note: Galactose-1-phosphate uridyl transferase; synthesizes glucose-1-phosphate and UDP-galactose from UDP-D-glucose and alpha-D-galactose-1-phosphate in the second step of galactose catabolism; human homolog UGP2 can complement yeast null mutant
codon start: 1
product: UDP-glucose:hexose-1-phosphate uridylyltransferase
translation: MTAEEFDFSSHSHRRYNPLTDSWILVSPHRAKRPWLGQQEAAYKPTAPLYDPKCYLCPGNKRATGNLNPRYESTYIFPNDYAAVRLDQPILPQNDSNEDNLKNRLLKVQSVRGNCFVICFSPNHNLTIPQMKQSDLVHIVNSWQALTDDLSREARENHKPFKYVQIFENKGTAMGCSNLHPHGQAWCLESIPSEVSQELKSFDKYKREHNTDLFADYVKLESREKSRVVVENESFIVVVPYWAIWPFETLVISKKKLASISQFNQMVKEDLASILKQLTIKYDNLFETSFPYSMGIHQAPLNATGDELSNSWFHMHFYPPLLRSATVRKFLVGFELLGEPQRDLTSEQAAEKLRNLDGQIHYLQRL
SIO_010081: YBR018C
subclass of: SO_0000673
so part of: YBR018C
location: complement(274427..275527)
location: region:274427-275527:-1
so has part: feature:274427-275527:-1:exon

NP_009574.1
type: Protein
SIO_000068: ncbiprotein

S000000222
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:274427-275527:-1:exon

YBR019C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GAL10
locus tag: YBR019C
so part of: sequence
location: complement(<276253..>278352)
location: region:276253-278352:-1
so has part: feature:276253-278352:-1:exon
subclass of: SO_0000010

852307
type: Gene
SIO_000068: ncbigene

position:276253:-1
position: 276253
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:278352:-1
position: 278352
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:276253-278352:-1:exon

YBR019C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GAL10
locus tag: YBR019C
product: bifunctional UDP-glucose 4-epimerase/aldose 1-epimerase
transcript id: NM_001178367.1
SIO_010081: YBR019C
subclass of: SO_0000673
so part of: YBR019C
location: complement(<276253..>278352)
location: region:276253-278352:-1
so has part: feature:276253-278352:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:276253-278352:-1:exon

YBR019C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GAL10
locus tag: YBR019C
EC number: 5.1.3.2
EC number: 5.1.3.3
experiment: EXISTENCE:direct assay:GO:0003978 UDP-glucose 4-epimerase activity [PMID:14764091]
experiment: EXISTENCE:direct assay:GO:0004034 aldose 1-epimerase activity [PMID:14764091]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:14764091]
experiment: EXISTENCE:direct assay:GO:0033499 galactose catabolic process via UDP-galactose [PMID:14764091]
experiment: EXISTENCE:mutant phenotype:GO:0003978 UDP-glucose 4-epimerase activity [PMID:14158615]
experiment: EXISTENCE:mutant phenotype:GO:0033499 galactose catabolic process via UDP-galactose [PMID:14158615]
note: UDP-glucose-4-epimerase; catalyzes interconversion of UDP-galactose and UDP-D-glucose in galactose metabolism; also catalyzes conversion of alpha-D-glucose or alpha-D-galactose to their beta-anomers; human homolog GALE implicated in galactosemia, can complement yeast null mutant
codon start: 1
product: bifunctional UDP-glucose 4-epimerase/aldose 1-epimerase
translation: MTAQLQSESTSKIVLVTGGAGYIGSHTVVELIENGYDCVVADNLSNSTYDSVARLEVLTKHHIPFYEVDLCDRKGLEKVFKEYKIDSVIHFAGLKAVGESTQIPLRYYHNNILGTVVLLELMQQYNVSKFVFSSSATVYGDATRFPNMIPIPEECPLGPTNPYGHTKYAIENILNDLYNSDKKSWKFAILRYFNPIGAHPSGLIGEDPLGIPNNLLPYMAQVAVGRREKLYIFGDDYDSRDGTPIRDYIHVVDLAKGHIAALQYLEAYNENEGLCREWNLGSGKGSTVFEVYHAFCKASGIDLPYKVTGRRAGDVLNLTAKPDRAKRELKWQTELQVEDSCKDLWKWTTENPFGYQLRGVEARFSAEDMRYDARFVTIGAGTRFQATFANLGASIVDLKVNGQSVVLGYENEEGYLNPDSAYIGATIGRYANRISKGKFSLCNKDYQLTVNNGVNANHSSIGSFHRKRFLGPIIQNPSKDVFTAEYMLIDNEKDTEFPGDLLVTIQYTVNVAQKSLEMVYKGKLTAGEATPINLTNHSYFNLNKPYGDTIEGTEIMVRSKKSVDVDKNMIPTGNIVDREIATFNSTKPTVLGPKNPQFDCCFVVDENAKPSQINTLNNELTLIVKAFHPDSNITLEVLSTEPTYQFYTGDFLSAGYEARQGFAIEPGRYIDAINQENWKDCVTLKNGETYGSKIVYRFS
SIO_010081: YBR019C
subclass of: SO_0000673
so part of: YBR019C
location: complement(276253..278352)
location: region:276253-278352:-1
so has part: feature:276253-278352:-1:exon

NP_009575.1
type: Protein
SIO_000068: ncbiprotein

S000000223
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:276253-278352:-1:exon

YNCB0008W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCB0008W
so part of: sequence
location: 276805..280645
location: region:276805-280645:1
so has part: feature:276805-280645:1:exon
subclass of: SO_0000011

65052914
type: Gene
SIO_000068: ncbigene

position:276805:1
position: 276805
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:280645:1
position: 280645
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:276805-280645:1:exon

YNCB0008W
type: Non Coding RNA
subclass of: SO_0000655
RO_0002162: 559292
nc RNA class: antisense_RNA
locus tag: YNCB0008W
product: uncharacterized ncRNA
note: lncRNA antisense to GAL10 and overlapping GAL1 mRNAs; GAL10-ncRNA transcription recruits Set2p methyltransferase and histone deacetylation activities in cis, leading to stable changes in chromatin structure; acts to enhance glucose repression of GAL1-10 induction at low environmental sugar concentrations; expression driven by Reb1p; does not appear to control GAL1 induction
transcript id: NR_172474.1
SIO_010081: YNCB0008W
subclass of: SO_0000673
so part of: YNCB0008W
location: 276805..280645
location: region:276805-280645:1
so has part: feature:276805-280645:1:exon

S000303802
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:276805-280645:1:exon

YBR020W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GAL1
locus tag: YBR020W
so part of: sequence
location: <279021..>280607
location: region:279021-280607:1
so has part: feature:279021-280607:1:exon
subclass of: SO_0000010

852308
type: Gene
SIO_000068: ncbigene

position:279021:1
position: 279021
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:280607:1
position: 280607
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:279021-280607:1:exon

YBR020W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GAL1
locus tag: YBR020W
product: galactokinase
transcript id: NM_001178368.1
SIO_010081: YBR020W
subclass of: SO_0000673
so part of: YBR020W
location: <279021..>280607
location: region:279021-280607:1
so has part: feature:279021-280607:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:279021-280607:1:exon

YBR020W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GAL1
locus tag: YBR020W
EC number: 2.7.1.6
experiment: EXISTENCE:direct assay:GO:0004335 galactokinase activity [PMID:14144]
experiment: EXISTENCE:direct assay:GO:0033499 galactose catabolic process via UDP-galactose [PMID:14144]
experiment: EXISTENCE:direct assay:GO:0046835 carbohydrate phosphorylation [PMID:14144]
experiment: EXISTENCE:genetic interaction:GO:0000411 positive regulation of transcription by galactose [PMID:2199310]
experiment: EXISTENCE:genetic interaction:GO:0005737 cytoplasm [PMID:2199310]
experiment: EXISTENCE:mutant phenotype:GO:0004335 galactokinase activity [PMID:13495476]
experiment: EXISTENCE:mutant phenotype:GO:0033499 galactose catabolic process via UDP-galactose [PMID:13495476]
note: Galactokinase; phosphorylates alpha-D-galactose to alpha-D-galactose-1-phosphate in the first step of galactose catabolism; expression regulated by Gal4p; human homolog GALK2 complements yeast null mutant; GAL1 has a paralog, GAL3, that arose from the whole genome duplication
codon start: 1
product: galactokinase
translation: MTKSHSEEVIVPEFNSSAKELPRPLAEKCPSIIKKFISAYDAKPDFVARSPGRVNLIGEHIDYCDFSVLPLAIDFDMLCAVKVLNEKNPSITLINADPKFAQRKFDLPLDGSYVTIDPSVSDWSNYFKCGLHVAHSFLKKLAPERFASAPLAGLQVFCEGDVPTGSGLSSSAAFICAVALAVVKANMGPGYHMSKQNLMRITVVAEHYVGVNNGGMDQAASVCGEEDHALYVEFKPQLKATPFKFPQLKNHEISFVIANTLVVSNKFETAPTNYNLRVVEVTTAANVLAATYGVVLLSGKEGSSTNKGNLRDFMNVYYARYHNISTPWNGDIESGIERLTKMLVLVEESLANKKQGFSVDDVAQSLNCSREEFTRDYLTTSPVRFQVLKLYQRAKHVYSESLRVLKAVKLMTTASFTADEDFFKQFGALMNESQASCDKLYECSCPEIDKICSIALSNGSYGSRLTGAGWGGCTVHLVPGGPNGNIEKVKEALANEFYKVKYPKITDAELENAIIVSKPALGSCLYEL
SIO_010081: YBR020W
subclass of: SO_0000673
so part of: YBR020W
location: 279021..280607
location: region:279021-280607:1
so has part: feature:279021-280607:1:exon

NP_009576.1
type: Protein
SIO_000068: ncbiprotein

S000000224
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:279021-280607:1:exon

YBR021W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FUR4
locus tag: YBR021W
so part of: sequence
location: <281443..>283344
location: region:281443-283344:1
so has part: feature:281443-283344:1:exon
subclass of: SO_0000010

852309
type: Gene
SIO_000068: ncbigene

position:281443:1
position: 281443
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:283344:1
position: 283344
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:281443-283344:1:exon

YBR021W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FUR4
locus tag: YBR021W
product: uracil permease
transcript id: NM_001178369.1
SIO_010081: YBR021W
subclass of: SO_0000673
so part of: YBR021W
location: <281443..>283344
location: region:281443-283344:1
so has part: feature:281443-283344:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:281443-283344:1:exon

YBR021W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FUR4
locus tag: YBR021W
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:8948441]
experiment: EXISTENCE:direct assay:GO:0015505 uracil:cation symporter activity [PMID:8948441]
experiment: EXISTENCE:direct assay:GO:0015857 uracil transport [PMID:8948441]
experiment: EXISTENCE:direct assay:GO:0032126 eisosome [PMID:15536122]
experiment: EXISTENCE:direct assay:GO:0055085 transmembrane transport [PMID:8948441]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
note: Plasma membrane localized uracil permease; expression is tightly regulated by uracil levels and environmental cues; conformational alterations induced by unfolding or substrate binding result in Rsp5p-mediated ubiquitination and degradation
codon start: 1
product: uracil permease
translation: MPDNLSLHLSGSSKRLNSRQLMESSNETFAPNNVDLEKEYKSSQSNITTEVYEASSFEEKVSSEKPQYSSFWKKIYYEYVVVDKSILGVSILDSFMYNQDLKPVEKERRVWSWYNYCYFWLAECFNINTWQIAATGLQLGLNWWQCWITIWIGYGFVGAFVVLASRVGSAYHLSFPISSRASFGIFFSLWPVINRVVMAIVWYSVQAYIAATPVSLMLKSIFGKDLQDKIPDHFGSPNATTYEFMCFFIFWAASLPFLLVPPHKIRHLFTVKAVLVPFASFGFLIWAIRRAHGRIALGSLTDVQPHGSAFSWAFLRSLMGCMANFSTMVINAPDFSRFSKNPNSALWSQLVCIPFLFSITCLIGILVTAAGYEIYGINYWSPLDVLEKFLQTTYNKGTRAGVFLISFVFAVAQLGTNISANSLSCGTDMSAIFPKFINIKRGSLFCAAMALCICPWNLMATSSKFTMALSAYAIFLSSIAGVVCSDYFVVRRGYIKLTHIYSHQKGSFYMYGNRFGINWRALAAYLCGVAPCLPGFIAEVGAPAIKVSDGAMKLYYLSYWVGYGLSFSSYTALCYFFPVPGCPVNNIIKDKGWFQRWANVDDFEEEWKDTIERDDLVDDNISVYEHEHEKTFI
SIO_010081: YBR021W
subclass of: SO_0000673
so part of: YBR021W
location: 281443..283344
location: region:281443-283344:1
so has part: feature:281443-283344:1:exon

NP_009577.1
type: Protein
SIO_000068: ncbiprotein

S000000225
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:281443-283344:1:exon

YBR022W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: POA1
locus tag: YBR022W
so part of: sequence
location: <283738..>284271
location: region:283738-284271:1
so has part: feature:283738-284271:1:exon
subclass of: SO_0000010

852310
type: Gene
SIO_000068: ncbigene

position:283738:1
position: 283738
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:284271:1
position: 284271
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:283738-284271:1:exon

YBR022W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: POA1
locus tag: YBR022W
product: ADP-ribose 1''-phosphate phosphatase
transcript id: NM_001178370.1
SIO_010081: YBR022W
subclass of: SO_0000673
so part of: YBR022W
location: <283738..>284271
location: region:283738-284271:1
so has part: feature:283738-284271:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:283738-284271:1:exon

YBR022W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: POA1
locus tag: YBR022W
EC number: 3.1.3.84
experiment: EXISTENCE:direct assay:GO:0016791 phosphatase activity [PMID:10550052|PMID:15684411]
experiment: EXISTENCE:direct assay:GO:0047407 ADP-ribosyl-[dinitrogen reductase] hydrolase activity [PMID:23474712]
note: Phosphatase that is highly specific for ADP-ribose 1''-phosphate; a tRNA splicing metabolite; may have a role in regulation of tRNA splicing
codon start: 1
product: ADP-ribose 1''-phosphate phosphatase
translation: MSNITYVKGNILKPKSYARILIHSCNCNGSWGGGIAYQLALRYPKAEKDYVEVCEKYGSNLLGKCILLPSYENSDLLICCLFTSSFGGSSHGEKQSILNYTKLALDKLKTFREAKDKTRTSEDSIGDYLNGHIKYPIGEYKLEMPQINSGIFGVPWKETERVLEEFSGDMSFTVYQL
SIO_010081: YBR022W
subclass of: SO_0000673
so part of: YBR022W
location: 283738..284271
location: region:283738-284271:1
so has part: feature:283738-284271:1:exon

NP_009578.1
type: Protein
SIO_000068: ncbiprotein

S000000226
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:283738-284271:1:exon

YBR023C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CAL1
alternative label: CSD2
alternative label: DIT101
alternative label: KTI2
gene: CHS3
locus tag: YBR023C
gene synonym: CAL1; CSD2; DIT101; KTI2
so part of: sequence
location: complement(<284428..>287925)
location: region:284428-287925:-1
so has part: feature:284428-287925:-1:exon
subclass of: SO_0000010

852311
type: Gene
SIO_000068: ncbigene

position:284428:-1
position: 284428
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:287925:-1
position: 287925
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:284428-287925:-1:exon

YBR023C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CAL1
alternative label: CSD2
alternative label: DIT101
alternative label: KTI2
gene: CHS3
locus tag: YBR023C
gene synonym: CAL1; CSD2; DIT101; KTI2
product: chitin synthase CHS3
transcript id: NM_001178371.1
SIO_010081: YBR023C
subclass of: SO_0000673
so part of: YBR023C
location: complement(<284428..>287925)
location: region:284428-287925:-1
so has part: feature:284428-287925:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:284428-287925:-1:exon

YBR023C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CAL1
alternative label: CSD2
alternative label: DIT101
alternative label: KTI2
gene: CHS3
locus tag: YBR023C
gene synonym: CAL1; CSD2; DIT101; KTI2
EC number: 2.4.1.16
experiment: EXISTENCE:direct assay:GO:0000131 incipient cellular bud site [PMID:9008706|PMID:15470103|PMID:8909536]
experiment: EXISTENCE:direct assay:GO:0005628 prospore membrane [PMID:15755916]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:9008706]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:15470103|PMID:8909536]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:19053807]
experiment: EXISTENCE:direct assay:GO:0045009 chitosome [PMID:8970154]
experiment: EXISTENCE:mutant phenotype:GO:0004100 chitin synthase activity [PMID:9760183]
experiment: EXISTENCE:mutant phenotype:GO:0030476 ascospore wall assembly [PMID:1293886]
experiment: EXISTENCE:mutant phenotype:GO:0034221 fungal-type cell wall chitin biosynthetic process [PMID:3280554]
experiment: EXISTENCE:mutant phenotype:GO:0097271 protein localization to bud neck [PMID:29405545]
note: Chitin synthase III; catalyzes the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for synthesis of the majority of cell wall chitin, the chitin ring during bud emergence, and spore wall chitosan; contains overlapping di-leucine and di-acidic signals that mediate, respectively, intracellular trafficking by AP-1 and trafficking to plasma membrane by exomer complex; requires AP-3 complex for its intracellular retention
codon start: 1
product: chitin synthase CHS3
translation: MTGLNGDDPDDYYLNLNQDEESLLRSRHSVGSGAPHRQGSLVRPERSRLNNPDNPHFYYAQKTQEQMNHLDVLPSSTGVNPNATRRSGSLRSKGSVRSKFSGRETDSYLLQDMNTTDKKASVKISDEGVAEDEFDKDGDVDNFEESSTQPINKSIKPLRKETNDTLSFWQMYCYFITFWAPAPILAFCGMPKKERQMAWREKVALISVILYIGAIVAFLTFGFTKTVCSSSKLRLKNNEVSTEFVVINGKAYELDTSSRSGIQDVEVDSDTLYGPWSDAGKDASFLFQNVNGNCHNLITPKSNSSIPHDDDNNLAWYFPCKLKNQDGSSKPNFTVENYAGWNCHTSKEDRDAFYGLKSKADVYFTWDGIKNSSRNLIVYNGDVLDLDLLDWLEKDDVDYPVVFDDLKTSNLQGYDLSLVLSNGHERKIARCLSEIIKVGEVDSKTVGCIASDVVLYVSLVFILSVVIIKFIIACYFRWTVARKQGAYIVDNKTMDKHTNDIEDWSNNIQTKAPLKEVDPHLRPKKYSKKSLGHKRASTFDLLKKHSSKMFQFNESVIDLDTSMSSSLQSSGSYRGMTTMTTQNAWKLSNENKAVHSRNPSTLLPTSSMFWNKATSSPVPGSSLIQSLDSTIIHPDIVQQPPLDFMPYGFPLIHTICFVTCYSEDEEGLRTTLDSLSTTDYPNSHKLLMVVCDGLIKGSGNDKTTPEIALGMMDDFVTPPDEVKPYSYVAVASGSKRHNMAKIYAGFYKYDDSTIPPENQQRVPIITIVKCGTPAEQGAAKPGNRGKRDSQIILMSFLEKITFDERMTQLEFQLLKNIWQITGLMADFYETVLMVDADTKVFPDALTHMVAEMVKDPLIMGLCGETKIANKAQSWVTAIQVFEYYISHHQAKAFESVFGSVTCLPGCFSMYRIKSPKGSDGYWVPVLANPDIVERYSDNVTNTLHKKNLLLLGEDRFLSSLMLKTFPKRKQVFVPKAACKTIAPDKFKVLLSQRRRWINSTVHNLFELVLIRDLCGTFCFSMQFVIGIELIGTMVLPLAICFTIYVIIFAIVSKPTPVITLVLLAIILGLPGLIVVITATRWSYLWWMCVYICALPIWNFVLPSYAYWKFDDFSWGDTRTIAGGNKKAQDENEGEFDHSKIKMRTWREFEREDILNRKEESDSFVA
SIO_010081: YBR023C
subclass of: SO_0000673
so part of: YBR023C
location: complement(284428..287925)
location: region:284428-287925:-1
so has part: feature:284428-287925:-1:exon

NP_009579.1
type: Protein
SIO_000068: ncbiprotein

S000000227
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:284428-287925:-1:exon

YBR024W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SCO2
locus tag: YBR024W
so part of: sequence
location: <289445..>290350
location: region:289445-290350:1
so has part: feature:289445-290350:1:exon
subclass of: SO_0000010

852312
type: Gene
SIO_000068: ncbigene

position:289445:1
position: 289445
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:290350:1
position: 290350
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:289445-290350:1:exon

YBR024W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SCO2
locus tag: YBR024W
product: putative thioredoxin peroxidase SCO2
transcript id: NM_001178372.1
SIO_010081: YBR024W
subclass of: SO_0000673
so part of: YBR024W
location: <289445..>290350
location: region:289445-290350:1
so has part: feature:289445-290350:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:289445-290350:1:exon

YBR024W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SCO2
locus tag: YBR024W
experiment: EXISTENCE:direct assay:GO:0005507 copper ion binding [PMID:25959673]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0031966 mitochondrial membrane [PMID:8702795]
experiment: EXISTENCE:genetic interaction:GO:0034599 cellular response to oxidative stress [PMID:30593977]
experiment: EXISTENCE:genetic interaction:GO:0045454 cell redox homeostasis [PMID:30593977]
note: Protein anchored to mitochondrial inner membrane; may have a redundant function with Sco1p in delivery of copper to cytochrome c oxidase; interacts with Cox2p; SCO2 has a paralog, SCO1, that arose from the whole genome duplication
codon start: 1
product: putative thioredoxin peroxidase SCO2
translation: MLNSSRKYACRSLFRQANVSIKGLFYNGGAYRRGFSTGCCLRSDNKESPSARQPLDRLQLGDEINEPEPIRTRFFQFSRWKATIALLLLSGGTYAYLSRKRRLLETEKEADANRAYGSVALGGPFNLTDFNGKPFTEENLKGKFSILYFGFSHCPDICPEELDRLTYWISELDDKDHIKIQPLFISCDPARDTPDVLKEYLSDFHPAIIGLTGTYDQVKSVCKKYKVYFSTPRDVKPNQDYLVDHSIFFYLIDPEGQFIDALGRNYDEQSGLEKIREQIQAYVPKEERERRSKKWYSFIFN
SIO_010081: YBR024W
subclass of: SO_0000673
so part of: YBR024W
location: 289445..290350
location: region:289445-290350:1
so has part: feature:289445-290350:1:exon

NP_009580.1
type: Protein
SIO_000068: ncbiprotein

S000000228
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:289445-290350:1:exon

YBR025C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: OLA1
locus tag: YBR025C
so part of: sequence
location: complement(<290681..>291865)
location: region:290681-291865:-1
so has part: feature:290681-291865:-1:exon
subclass of: SO_0000010

852313
type: Gene
SIO_000068: ncbigene

position:290681:-1
position: 290681
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:291865:-1
position: 291865
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:290681-291865:-1:exon

YBR025C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: OLA1
locus tag: YBR025C
product: Obg-like ATPase
transcript id: NM_001178373.1
SIO_010081: YBR025C
subclass of: SO_0000673
so part of: YBR025C
location: complement(<290681..>291865)
location: region:290681-291865:-1
so has part: feature:290681-291865:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:290681-291865:-1:exon

YBR025C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: OLA1
locus tag: YBR025C
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:10684247]
experiment: EXISTENCE:direct assay:GO:0010494 cytoplasmic stress granule [PMID:26359986]
experiment: EXISTENCE:direct assay:GO:0016887 ATP hydrolysis activity [PMID:17430889]
experiment: EXISTENCE:mutant phenotype:GO:1900036 positive regulation of cellular response to heat [PMID:34571008]
note: P-loop ATPase with similarity to human OLA1 and bacterial YchF; identified as specifically interacting with the proteasome; positively regulates heat shock response; null mutant displays increased translation rate and increased readthrough of premature stop codons; protein abundance increases in response to hydrogen peroxide and to DNA replication stress
codon start: 1
product: Obg-like ATPase
translation: MPPKKQVEEKKVLLGRPGNNLKAGIVGLANVGKSTFFQAITRCPLGNPANYPFATIDPEEARVIVPSPRFDKLCEIYKKTASEVPAHLTVYDIAGLTKGASAGEGLGNAFLSHIRSVDSIYQVVRCFDDAEIIHVEGDVDPVRDLEIINQELRLKDIEFAQKALEGAEKIAKRGGQSLEVKQKKEEMDLITKIIKLLESGQRVANHSWTSKEVEIINSMFLLTAKPCIYLINLSERDYIRKKNKHLLRIKEWVDKYSPGDLIIPFSVSLEERLSHMSPEDAEEELKKLQTISALPKIITTMRQKLDLISFFTCGPDEVREWTIRRGTKAPQAAGVIHNDLMNTFILAQVMKCEDVFEYKDDSAIKAAGKLMQKGKDYVVEDGDIIYFRAGAGKN
SIO_010081: YBR025C
subclass of: SO_0000673
so part of: YBR025C
location: complement(290681..291865)
location: region:290681-291865:-1
so has part: feature:290681-291865:-1:exon

NP_009581.1
type: Protein
SIO_000068: ncbiprotein

S000000229
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:290681-291865:-1:exon

YBR026C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MRF1
alternative label: MRF1'
gene: ETR1
locus tag: YBR026C
gene synonym: MRF1; MRF1'
so part of: sequence
location: complement(<292877..>294019)
location: region:292877-294019:-1
so has part: feature:292877-294019:-1:exon
subclass of: SO_0000010

852314
type: Gene
SIO_000068: ncbigene

position:292877:-1
position: 292877
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:294019:-1
position: 294019
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:292877-294019:-1:exon

YBR026C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MRF1
alternative label: MRF1'
gene: ETR1
locus tag: YBR026C
gene synonym: MRF1; MRF1'
product: enoyl-[acyl-carrier-protein] reductase
transcript id: NM_001178374.1
SIO_010081: YBR026C
subclass of: SO_0000673
so part of: YBR026C
location: complement(<292877..>294019)
location: region:292877-294019:-1
so has part: feature:292877-294019:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:292877-294019:-1:exon

YBR026C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MRF1
alternative label: MRF1'
gene: ETR1
locus tag: YBR026C
gene synonym: MRF1; MRF1'
EC number: 1.3.1.104
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:11509667|PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0016631 enoyl-[acyl-carrier-protein] reductase activity [PMID:11509667]
experiment: EXISTENCE:mutant phenotype:GO:0006633 fatty acid biosynthetic process [PMID:11509667]
experiment: EXISTENCE:mutant phenotype:GO:0009060 aerobic respiration [PMID:11509667]
note: 2-enoyl thioester reductase; member of the medium chain dehydrogenase/reductase family; localized to mitochondria, where it has a probable role in fatty acid synthesis; human MECR functionally complements the respiratory growth defect of the null mutant
codon start: 1
product: enoyl-[acyl-carrier-protein] reductase
translation: MLPTFKRYMSSSAHQIPKHFKSLIYSTHEVEDCTKVLSVKNYTPKQDLSQSIVLKTLAFPINPSDINQLQGVYPSRPEKTYDYSTDEPAAIAGNEGVFEVVSLPSGSSKGDLKLGDRVIPLQANQGTWSNYRVFSSSSDLIKVNDLDLFSAATVSVNGCTGFQLVSDYIDWNSNGNEWIIQNAGTSSVSKIVTQVAKAKGIKTLSVIRDRDNFDEVAKVLEDKYGATKVISESQNNDKTFAKEVLSKILGENARVRLALNSVGGKSSASIARKLENNALMLTYGGMSKQPVTLPTSLHIFKGLTSKGYWVTEKNKKNPQSKIDTISDFIKMYNYGHIISPRDEIETLTWNTNTTTDEQLLELVKKGITGKGKKKMVVLEW
SIO_010081: YBR026C
subclass of: SO_0000673
so part of: YBR026C
location: complement(292877..294019)
location: region:292877-294019:-1
so has part: feature:292877-294019:-1:exon

NP_009582.1
type: Protein
SIO_000068: ncbiprotein

S000000230
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:292877-294019:-1:exon

YBR027C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBR027C
so part of: sequence
location: complement(<294024..>294356)
location: region:294024-294356:-1
so has part: feature:294024-294356:-1:exon
subclass of: SO_0000010

852315
type: Gene
SIO_000068: ncbigene

position:294024:-1
position: 294024
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:294356:-1
position: 294356
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:294024-294356:-1:exon

YBR027C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBR027C
product: uncharacterized protein
transcript id: NM_001346795.1
SIO_010081: YBR027C
subclass of: SO_0000673
so part of: YBR027C
location: complement(<294024..>294356)
location: region:294024-294356:-1
so has part: feature:294024-294356:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:294024-294356:-1:exon

YBR027C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBR027C
note: hypothetical protein; conserved among S. cerevisiae strains; YBR027C is not an essential gene
codon start: 1
product: uncharacterized protein
translation: MFKGSVSLYILCFALGLRNTFLIYNVCNNIKNNCMDNTSGPIGDTIFLIYGIIIIIGPRRCFFFYLKRVVLLQGTHEWCTQGLFPWLKKLEITNVHCHLRRFIICQLHLI
SIO_010081: YBR027C
subclass of: SO_0000673
so part of: YBR027C
location: complement(294024..294356)
location: region:294024-294356:-1
so has part: feature:294024-294356:-1:exon

NP_001333724.1
type: Protein
SIO_000068: ncbiprotein

S000000231
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:294024-294356:-1:exon

YBR028C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: YPK3
locus tag: YBR028C
so part of: sequence
location: complement(<294425..>296002)
location: region:294425-296002:-1
so has part: feature:294425-296002:-1:exon
subclass of: SO_0000010

852316
type: Gene
SIO_000068: ncbigene

position:294425:-1
position: 294425
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:296002:-1
position: 296002
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:294425-296002:-1:exon

YBR028C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: YPK3
locus tag: YBR028C
product: putative protein kinase YPK3
transcript id: NM_001178376.1
SIO_010081: YBR028C
subclass of: SO_0000673
so part of: YBR028C
location: complement(<294425..>296002)
location: region:294425-296002:-1
so has part: feature:294425-296002:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:294425-296002:-1:exon

YBR028C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: YPK3
locus tag: YBR028C
EC number: 2.7.11.1
experiment: EXISTENCE:direct assay:GO:0004674 protein serine/threonine kinase activity [PMID:26582391]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22289182|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0018105 peptidyl-serine phosphorylation [PMID:26582391]
experiment: EXISTENCE:direct assay:GO:0046777 protein autophosphorylation [PMID:26582391]
experiment: EXISTENCE:genetic interaction:GO:0004674 protein serine/threonine kinase activity [PMID:26582391]
experiment: EXISTENCE:genetic interaction:GO:0018105 peptidyl-serine phosphorylation [PMID:26582391]
experiment: EXISTENCE:mutant phenotype:GO:0004674 protein serine/threonine kinase activity [PMID:26582391]
experiment: EXISTENCE:mutant phenotype:GO:0018105 peptidyl-serine phosphorylation [PMID:25767889|PMID:26582391]
experiment: EXISTENCE:mutant phenotype:GO:0046777 protein autophosphorylation [PMID:26582391]
note: AGC kinase; phosphorylated by cAMP-dependent protein kinase (PKA) in a TORC1-dependent manner; directly phosphorylated by TORC1; phosphorylates ribosomal protein Rps6a/b (S6), in a TORC-dependent manner; undergoes autophosphorylation
codon start: 1
product: putative protein kinase YPK3
translation: MIFSLDEELHRVSLDDKKNDIKVDYSSAIYNDINHEQGSSITYEESINHLSVHSNAIPLNGMSPAHRMRRRSSAYSKFPILTPPNTRRFSITGSDAMRTNTNRLSITPQDIISSNIGENELSRNLHDFKPVRVLGQGAYGKVLLVKDVNTSKLYAMKQLRKAEILISQTATDSKREDEDKNDGNNNDNDDGLSKRLERTFAERSILSEIEHPNIVKLFYSFHDNSKLYLLLQYIPGGELFYHLKEHGTLDETTVSFYAAEISCALRFLHTKGVVYRDLKPENCLLNQRGHLVLTDFGLSKKSANDSAVDEEDPENVNALYSIIGTPEYCAPEILLGKAYSQNCDWYSLGCLLYDMLVGKPPYTGSNHKVIINKIQQNKQGPKIPFYLSEGMKDILNALLKKETAKRWNVDKYWAKTGANNKPTKSKKKKSGAARTSLFTEHFIFRKIDWKLLESGQLQKTTLGPIVPVITDLELAENFDTEFTSMSYEETYTDSKPININSVSKSPDMFKGFSYKASGSYLEKYF
SIO_010081: YBR028C
subclass of: SO_0000673
so part of: YBR028C
location: complement(294425..296002)
location: region:294425-296002:-1
so has part: feature:294425-296002:-1:exon

NP_009584.1
type: Protein
SIO_000068: ncbiprotein

S000000232
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:294425-296002:-1:exon

YBR029C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CDG1
gene: CDS1
locus tag: YBR029C
gene synonym: CDG1
so part of: sequence
location: complement(<296369..>297742)
location: region:296369-297742:-1
so has part: feature:296369-297742:-1:exon
subclass of: SO_0000010

852317
type: Gene
SIO_000068: ncbigene

position:296369:-1
position: 296369
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:297742:-1
position: 297742
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:296369-297742:-1:exon

YBR029C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CDG1
gene: CDS1
locus tag: YBR029C
gene synonym: CDG1
product: phosphatidate cytidylyltransferase
transcript id: NM_001178377.1
SIO_010081: YBR029C
subclass of: SO_0000673
so part of: YBR029C
location: complement(<296369..>297742)
location: region:296369-297742:-1
so has part: feature:296369-297742:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:296369-297742:-1:exon

YBR029C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CDG1
gene: CDS1
locus tag: YBR029C
gene synonym: CDG1
EC number: 2.7.7.41
experiment: EXISTENCE:direct assay:GO:0004605 phosphatidate cytidylyltransferase activity [PMID:8557688]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:23623749|PMID:8557688|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0070319 Golgi to plasma membrane transport vesicle [PMID:2163397]
experiment: EXISTENCE:mutant phenotype:GO:0006658 phosphatidylserine metabolic process [PMID:2832385]
experiment: EXISTENCE:mutant phenotype:GO:0016024 CDP-diacylglycerol biosynthetic process [PMID:2832385]
experiment: EXISTENCE:mutant phenotype:GO:0046488 phosphatidylinositol metabolic process [PMID:2832385|PMID:8557688]
note: Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase); an enzyme that catalyzes that conversion of CTP + phosphate into diphosphate + CDP-diaclglyerol, a critical step in the synthesis of all major yeast phospholipids; human homolog CDS1 can complement yeast cds1 null mutant
codon start: 1
product: phosphatidate cytidylyltransferase
translation: MSDNPEMKPHGTSKEIVESVTDATSKAIDKLQEELHKDASESVTPVTKESTAATKESRKYNFFIRTVWTFVMISGFFITLASGHAWCIVLILGCQIATFKECIAVTSASGREKNLPLTKTLNWYLLFTTIYYLDGKSLFKFFQATFYEYPVLNFIVTNHKFICYCLYLMGFVLFVCSLRKGFLKFQFGSLCVTHMVLLLVVFQAHLIIKNVLNGLFWFLLPCGLVIVNDIFAYLCGITFGKTKLIEISPKKTLEGFLGAWFFTALASIILTRILSPYTYLTCPVEDLHTNFFSNLTCELNPVFLPQVYRLPPIFFDKVQINSITVKPIYFHALNLATFASLFAPFGGFFASGLKRTFKVKDFGHSIPGHGGITDRVDCQFIMGSFANLYYETFISEHRITVDTVLSTILMNLNDKQIIELIDILIRFLSKKGIISAKNFEKLADIFNVTKKSLTNHS
SIO_010081: YBR029C
subclass of: SO_0000673
so part of: YBR029C
location: complement(296369..297742)
location: region:296369-297742:-1
so has part: feature:296369-297742:-1:exon

NP_009585.1
type: Protein
SIO_000068: ncbiprotein

S000000233
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:296369-297742:-1:exon

YBR030W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RKM3
locus tag: YBR030W
so part of: sequence
location: <298292..>299950
location: region:298292-299950:1
so has part: feature:298292-299950:1:exon
subclass of: SO_0000010

852318
type: Gene
SIO_000068: ncbigene

position:298292:1
position: 298292
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:299950:1
position: 299950
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:298292-299950:1:exon

YBR030W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RKM3
locus tag: YBR030W
product: protein-lysine N-methyltransferase
transcript id: NM_001178378.1
SIO_010081: YBR030W
subclass of: SO_0000673
so part of: YBR030W
location: <298292..>299950
location: region:298292-299950:1
so has part: feature:298292-299950:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:298292-299950:1:exon

YBR030W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RKM3
locus tag: YBR030W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22932476|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:22932476]
experiment: EXISTENCE:genetic interaction:GO:0016279 protein-lysine N-methyltransferase activity [PMID:18957409]
experiment: EXISTENCE:genetic interaction:GO:0018026 peptidyl-lysine monomethylation [PMID:18957409]
experiment: EXISTENCE:mutant phenotype:GO:0016279 protein-lysine N-methyltransferase activity [PMID:18957409]
experiment: EXISTENCE:mutant phenotype:GO:0018026 peptidyl-lysine monomethylation [PMID:18957409|PMID:24517342]
note: Ribosomal lysine methyltransferase; specific for monomethylation of Rpl42ap and Rpl42bp (lysine 40); nuclear SET domain containing protein; relocalizes to the cytosol in response to hypoxia
codon start: 1
product: protein-lysine N-methyltransferase
translation: MSVTFKDDVHRILKFVANCNGRFEDSKCDIRESPLGGLGVFAKTDIAEGESILTLNKSSIFSASNSSIANLLCDSSIDGMLALNIAFIYETTVFRNSSHWYPFLRTIRIRDDEGHLNLPPSFWHADAKRLLKGTSFDTLFDSLAPEEEIMEGFEIAVDLAHKWNDEFGLEIPKGFLDVSEENHEEDYNLKLEKFISVAYTLSSRGFEIDAYHETALVPIADLFNHHVSDPDLKFVSLYDVCDKCGEPDMCKHLIAEEYLEAENLDKNMPKVASMETRVIDEDLIKSLENDLEKEYSNVTANIEDDDGGIENPDECVDLVLKNDVAQGQEIFNSYGELSNVFLLARYGFTVPENQYDIVHLGPDFMKILKKEEKYQEKVKWWSQVGHGLFSAWYAQMRQEDEEDEDGQAKSDNLSDDIESEEEEEEEEGDDSLESWLSQLYIDSSGEPSPSTWALANLLTLTAVQWESLFSKKATPHISDSIVNEEKLPFLAKKDNPHSKKLLSNLLKEKQLPCIKGDNSSKITSATKSMLQNARTLVQSEHNILDRCLKRLS
SIO_010081: YBR030W
subclass of: SO_0000673
so part of: YBR030W
location: 298292..299950
location: region:298292-299950:1
so has part: feature:298292-299950:1:exon

NP_009586.1
type: Protein
SIO_000068: ncbiprotein

S000000234
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:298292-299950:1:exon

YBR031W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RPL4A
locus tag: YBR031W
so part of: sequence
location: <300166..>301254
location: region:300166-301254:1
so has part: feature:300166-301254:1:exon
subclass of: SO_0000010

852319
type: Gene
SIO_000068: ncbigene

position:300166:1
position: 300166
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:301254:1
position: 301254
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:300166-301254:1:exon

YBR031W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RPL4A
locus tag: YBR031W
product: ribosomal 60S subunit protein L4A
transcript id: NM_001178379.1
SIO_010081: YBR031W
subclass of: SO_0000673
so part of: YBR031W
location: <300166..>301254
location: region:300166-301254:1
so has part: feature:300166-301254:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:300166-301254:1:exon

YBR031W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RPL4A
locus tag: YBR031W
experiment: EXISTENCE:curator inference:GO:0002181 cytoplasmic translation [PMID:11983894]
experiment: EXISTENCE:curator inference:GO:0003735 structural constituent of ribosome [PMID:11983894]
experiment: EXISTENCE:direct assay:GO:0022625 cytosolic large ribosomal subunit [PMID:11983894]
note: Ribosomal 60S subunit protein L4A; N-terminally acetylated; homologous to mammalian ribosomal protein L4 and bacterial L4; RPL4A has a paralog, RPL4B, that arose from the whole genome duplication
codon start: 1
product: ribosomal 60S subunit protein L4A
translation: MSRPQVTVHSLTGEATANALPLPAVFSAPIRPDIVHTVFTSVNKNKRQAYAVSEKAGHQTSAESWGTGRAVARIPRVGGGGTGRSGQGAFGNMCRGGRMFAPTKTWRKWNVKVNHNEKRYATASAIAATAVASLVLARGHRVEKIPEIPLVVSTDLESIQKTKEAVAALKAVGAHSDLLKVLKSKKLRAGKGKYRNRRWTQRRGPLVVYAEDNGIVKALRNVPGVETANVASLNLLQLAPGAHLGRFVIWTEAAFTKLDQVWGSETVASSKVGYTLPSHIISTSDVTRIINSSEIQSAIRPAGQATQKRTHVLKKNPLKNKQVLLRLNPYAKVFAAEKLGSKKAEKTGTKPAAVFTETLKHD
SIO_010081: YBR031W
subclass of: SO_0000673
so part of: YBR031W
location: 300166..301254
location: region:300166-301254:1
so has part: feature:300166-301254:1:exon

NP_009587.1
type: Protein
SIO_000068: ncbiprotein

S000000235
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:300166-301254:1:exon

YBR032W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBR032W
so part of: sequence
location: <301519..>301821
location: region:301519-301821:1
so has part: feature:301519-301821:1:exon
subclass of: SO_0000010

852320
type: Gene
SIO_000068: ncbigene

position:301519:1
position: 301519
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:301821:1
position: 301821
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:301519-301821:1:exon

YBR032W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBR032W
product: uncharacterized protein
transcript id: NM_001346796.1
SIO_010081: YBR032W
subclass of: SO_0000673
so part of: YBR032W
location: <301519..>301821
location: region:301519-301821:1
so has part: feature:301519-301821:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:301519-301821:1:exon

YBR032W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBR032W
note: hypothetical protein; conserved among S. cerevisiae strains; YBR032W is not an essential gene
codon start: 1
product: uncharacterized protein
translation: MVIIRITLSNLLREKGDLCLELLRVDKGIYPFDTSQPIGSMQVLLPHASNYPGSAQFYLFDAATKLGFEQSVNLNYSENHWLNNTPCQYLYVFLQQARLE
SIO_010081: YBR032W
subclass of: SO_0000673
so part of: YBR032W
location: 301519..301821
location: region:301519-301821:1
so has part: feature:301519-301821:1:exon

NP_001333725.1
type: Protein
SIO_000068: ncbiprotein

S000000236
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:301519-301821:1:exon

YBR033W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: EDS1
locus tag: YBR033W
so part of: sequence
location: <301944..>304703
location: region:301944-304703:1
so has part: feature:301944-304703:1:exon
subclass of: SO_0000010

852321
type: Gene
SIO_000068: ncbigene

position:301944:1
position: 301944
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:304703:1
position: 304703
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:301944-304703:1:exon

YBR033W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: EDS1
locus tag: YBR033W
product: Eds1p
transcript id: NM_001178381.1
SIO_010081: YBR033W
subclass of: SO_0000673
so part of: YBR033W
location: <301944..>304703
location: region:301944-304703:1
so has part: feature:301944-304703:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:301944-304703:1:exon

YBR033W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: EDS1
locus tag: YBR033W
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:19111667]
note: Putative zinc cluster protein, predicted to be a transcription factor; not an essential gene; EDS1 has a paralog, RGT1, that arose from the whole genome duplication
codon start: 1
product: Eds1p
translation: MSHHVPNLYGTPIRDPHERKRNSASMGEVNQSVSSRNCERGSEKGTKQRKKASHACDQCRRKRIKCRFDKHTGVCQGCLEVGEKCQFIRVPLKRGPAKKRGSVVSIEKFSSDNDPLQYRPRTHSYPMNSGNNYLPSLARNSSFPSISSLFVPSITAQSQQFVKVPYDDIKRRSSLAILGSDSSISTEFGGNYRLDENLNVRQEGKDIVAKGMITPVEEMGACSSNVRRQGSQSLPIQEQRASPYINPFISGRSRLSSLSYTSEATTSEGNTQGKNQCMLTPNSVRSIEKERLNSLTAGFPNKKLGTDGRSDKWDKNSTWKPVYRSSNPSHPSTEKNVSLNQEASAKPLMLGTYRQFDATSFYKVLGIYYNFFHINFPVIPINKSKFTDMLDPEKPNVIDEIRQINNEIIQCFKTALEVLVFCKIKQRRSSKSTKSWSRDSLCDFQKGLYYIQNFNKCIADCFQSLITIKPVLKQNSSVIPSRIKFIYFSTIIVLNFILILAGEESSLLLGPSVGVFNEFQAHKLFLPFQNTSPMLLLNSNEESGDEILDYAVLFKRLYILLNILDTLQSFRLGQPKLINLNFGSAIETYFSDKTGHNQVVEKAPVALDNILRNLKLGEFITYFVLNRKSLQVNVPHHLLFTNQTDYGEFAVEKGEHDNIAGKFETLLKKKEILIRKLLNIEQKNDHILENCCNSDAEMKNIGELVCSMITLVSGILDSITNMNAENSVDLDSKPLPNAYFAQDSEEELMSPTQSITSNLASEENTRCTTKDLMGTVSIFMLPMVEECYNIISLIGPIPTTLISLYIRNGNMAKGINDRIMTLSTALNELVQITALFNTLEPFRKNAHDRAKRYYVSATSSTGCYESVMKSMYSGKCAASNASNVAPSEEENKKILKKFADIGWKLMDDSELGCCCCFFN
SIO_010081: YBR033W
subclass of: SO_0000673
so part of: YBR033W
location: 301944..304703
location: region:301944-304703:1
so has part: feature:301944-304703:1:exon

NP_009589.1
type: Protein
SIO_000068: ncbiprotein

S000000237
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:301944-304703:1:exon

YBR034C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: HCP1
alternative label: ODP1
alternative label: RMT1
gene: HMT1
locus tag: YBR034C
gene synonym: HCP1; ODP1; RMT1
so part of: sequence
location: complement(<304930..>305976)
location: region:304930-305976:-1
so has part: feature:304930-305976:-1:exon
subclass of: SO_0000010

852322
type: Gene
SIO_000068: ncbigene

position:304930:-1
position: 304930
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:305976:-1
position: 305976
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:304930-305976:-1:exon

YBR034C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: HCP1
alternative label: ODP1
alternative label: RMT1
gene: HMT1
locus tag: YBR034C
gene synonym: HCP1; ODP1; RMT1
product: protein-arginine omega-N methyltransferase HMT1
transcript id: NM_001178382.1
SIO_010081: YBR034C
subclass of: SO_0000673
so part of: YBR034C
location: complement(<304930..>305976)
location: region:304930-305976:-1
so has part: feature:304930-305976:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:304930-305976:-1:exon

YBR034C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: HCP1
alternative label: ODP1
alternative label: RMT1
gene: HMT1
locus tag: YBR034C
gene synonym: HCP1; ODP1; RMT1
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:8668183]
experiment: EXISTENCE:direct assay:GO:0018216 peptidyl-arginine methylation [PMID:22997150|PMID:25715670|PMID:8647869]
experiment: EXISTENCE:direct assay:GO:0035241 protein-arginine omega-N monomethyltransferase activity [PMID:8647869]
experiment: EXISTENCE:direct assay:GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity [PMID:8647869]
experiment: EXISTENCE:mutant phenotype:GO:0006406 mRNA export from nucleus [PMID:8668183]
experiment: EXISTENCE:mutant phenotype:GO:0018216 peptidyl-arginine methylation [PMID:18515076|PMID:20035717|PMID:8647869]
experiment: EXISTENCE:mutant phenotype:GO:0032968 positive regulation of transcription elongation by RNA polymerase II [PMID:20053728]
experiment: EXISTENCE:mutant phenotype:GO:0035241 protein-arginine omega-N monomethyltransferase activity [PMID:8647869]
experiment: EXISTENCE:mutant phenotype:GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity [PMID:8647869]
experiment: EXISTENCE:mutant phenotype:GO:0046656 folic acid biosynthetic process [PMID:31515157]
experiment: EXISTENCE:mutant phenotype:GO:0060567 negative regulation of termination of DNA-templated transcription [PMID:20053728]
note: Nuclear SAM-dependent mono- and asymmetric methyltransferase; modifies hnRNPs, including Npl3p and Hrp1p, affecting their activity and nuclear export; methylates U1 snRNP protein Snp1p, ribosomal protein Rps2p, and histones H3 and H4; interacts genetically with genes encoding components of Rpd3(L) and this interaction is important for Rpd3 recruitment to the subtelomeric region
codon start: 1
product: protein-arginine omega-N methyltransferase HMT1
translation: MSKTAVKDSATEKTKLSESEQHYFNSYDHYGIHEEMLQDTVRTLSYRNAIIQNKDLFKDKIVLDVGCGTGILSMFAAKHGAKHVIGVDMSSIIEMAKELVELNGFSDKITLLRGKLEDVHLPFPKVDIIISEWMGYFLLYESMMDTVLYARDHYLVEGGLIFPDKCSIHLAGLEDSQYKDEKLNYWQDVYGFDYSPFVPLVLHEPIVDTVERNNVNTTSDKLIEFDLNTVKISDLAFKSNFKLTAKRQDMINGIVTWFDIVFPAPKGKRPVEFSTGPHAPYTHWKQTIFYFPDDLDAETGDTIEGELVCSPNEKNNRDLNIKISYKFESNGIDGNSRSRKNEGSYLMH
SIO_010081: YBR034C
subclass of: SO_0000673
so part of: YBR034C
location: complement(304930..305976)
location: region:304930-305976:-1
so has part: feature:304930-305976:-1:exon

NP_009590.1
type: Protein
SIO_000068: ncbiprotein

S000000238
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:304930-305976:-1:exon

YBR035C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PDX3
locus tag: YBR035C
so part of: sequence
location: complement(<306269..>306955)
location: region:306269-306955:-1
so has part: feature:306269-306955:-1:exon
subclass of: SO_0000010

852323
type: Gene
SIO_000068: ncbigene

position:306269:-1
position: 306269
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:306955:-1
position: 306955
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:306269-306955:-1:exon

YBR035C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PDX3
locus tag: YBR035C
product: pyridoxamine-phosphate oxidase PDX3
transcript id: NM_001178383.1
SIO_010081: YBR035C
subclass of: SO_0000673
so part of: YBR035C
location: complement(<306269..>306955)
location: region:306269-306955:-1
so has part: feature:306269-306955:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:306269-306955:-1:exon

YBR035C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PDX3
locus tag: YBR035C
EC number: 1.4.3.5
experiment: EXISTENCE:curator inference:GO:0009443 pyridoxal 5'-phosphate salvage [PMID:7896706]
experiment: EXISTENCE:direct assay:GO:0004733 pyridoxamine-phosphate oxidase activity [PMID:26327315]
experiment: EXISTENCE:direct assay:GO:0005758 mitochondrial intermembrane space [PMID:22984289]
experiment: EXISTENCE:direct assay:GO:0010181 FMN binding [PMID:26327315]
experiment: EXISTENCE:mutant phenotype:GO:0004733 pyridoxamine-phosphate oxidase activity [PMID:7896706]
note: Pyridoxine (pyridoxamine) phosphate oxidase; has homologs in E. coli and Myxococcus xanthus; transcription is under the general control of nitrogen metabolism
codon start: 1
product: pyridoxamine-phosphate oxidase PDX3
translation: MTKQAEETQKPIIFAPETYQYDKFTLNEKQLTDDPIDLFTKWFNEAKEDPRETLPEAITFSSAELPSGRVSSRILLFKELDHRGFTIYSNWGTSRKAHDIATNPNAAIVFFWKDLQRQVRVEGITEHVNRETSERYFKTRPRGSKIGAWASRQSDVIKNREELDELTQKNTERFKDAEDIPCPDYWGGLRIVPLEIEFWQGRPSRLHDRFVYRRKTENDPWKVVRLAP
SIO_010081: YBR035C
subclass of: SO_0000673
so part of: YBR035C
location: complement(306269..306955)
location: region:306269-306955:-1
so has part: feature:306269-306955:-1:exon

NP_009591.1
type: Protein
SIO_000068: ncbiprotein

S000000239
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:306269-306955:-1:exon

YNCB0009C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SNR161
locus tag: YNCB0009C
so part of: sequence
location: complement(307185..307345)
location: region:307185-307345:-1
so has part: feature:307185-307345:-1:exon
subclass of: SO_0000578

9164869
type: Gene
SIO_000068: ncbigene

position:307185:-1
position: 307185
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:307345:-1
position: 307345
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:307185-307345:-1:exon

YNCB0009C
type: Non Coding RNA
subclass of: SO_0000655
RO_0002162: 559292
nc RNA class: snoRNA
gene: SNR161
locus tag: YNCB0009C
product: SNR161
experiment: EXISTENCE:curator inference:GO:0005730 nucleolus [PMID:15306656]
experiment: EXISTENCE:mutant phenotype:GO:0030559 rRNA pseudouridylation guide activity [PMID:15306656|PMID:15923376]
experiment: EXISTENCE:mutant phenotype:GO:0031118 rRNA pseudouridine synthesis [PMID:15306656|PMID:15923376]
experiment: EXISTENCE:physical interaction:GO:0031429 box H/ACA snoRNP complex [PMID:15923376]
note: H/ACA small nucleolar RNA (snoRNA); guides pseudouridylation of small subunit (SSU) rRNA at positions U632 and U766
transcript id: NR_132152.1
SIO_010081: YNCB0009C
subclass of: SO_0000673
so part of: YNCB0009C
location: complement(307185..307345)
location: region:307185-307345:-1
so has part: feature:307185-307345:-1:exon

S000087162
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:307185-307345:-1:exon

YNCB0010W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TLC1
locus tag: YNCB0010W
so part of: sequence
location: 307587..308887
location: region:307587-308887:1
so has part: feature:307587-308887:1:exon
subclass of: SO_0000011

9164870
type: Gene
SIO_000068: ncbigene

position:307587:1
position: 307587
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:308887:1
position: 308887
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:307587-308887:1:exon

YNCB0010W
type: Non Coding RNA
subclass of: SO_0000655
RO_0002162: 559292
nc RNA class: telomerase_RNA
gene: TLC1
locus tag: YNCB0010W
product: TLC1
experiment: EXISTENCE:direct assay:GO:0000333 telomerase catalytic core complex [PMID:15813705]
experiment: EXISTENCE:direct assay:GO:0003720 telomerase activity [PMID:15813705]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:12101098]
experiment: EXISTENCE:direct assay:GO:0005697 telomerase holoenzyme complex [PMID:10898986]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:12101098]
experiment: EXISTENCE:direct assay:GO:0007004 telomere maintenance via telomerase [PMID:15813705]
experiment: EXISTENCE:mutant phenotype:GO:0000722 telomere maintenance via recombination [PMID:23390378|PMID:25822194]
experiment: EXISTENCE:mutant phenotype:GO:0007004 telomere maintenance via telomerase [PMID:15813705]
note: RNA template component of telomerase; flexible scaffold that tethers telomerase holoenzyme protein subunits to the complex; contains template sequence that Est2p uses to add irregular repeats of TG(1-3) residues onto a DNA end; promoter regulated by the cell cycle dependent transcriptional activators Swi4p/Swi6p and Mbp1p/Swi6p
transcript id: NR_132153.1
SIO_010081: YNCB0010W
subclass of: SO_0000673
so part of: YNCB0010W
location: 307587..308887
location: region:307587-308887:1
so has part: feature:307587-308887:1:exon

S000006657
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:307587-308887:1:exon

YBR036C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CLS2
gene: CSG2
locus tag: YBR036C
gene synonym: CLS2
so part of: sequence
location: complement(<309081..>310313)
location: region:309081-310313:-1
so has part: feature:309081-310313:-1:exon
subclass of: SO_0000010

852324
type: Gene
SIO_000068: ncbigene

position:309081:-1
position: 309081
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:310313:-1
position: 310313
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:309081-310313:-1:exon

YBR036C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CLS2
gene: CSG2
locus tag: YBR036C
gene synonym: CLS2
product: mannosylinositol phosphorylceramide synthase regulatory subunit
transcript id: NM_001178384.1
SIO_010081: YBR036C
subclass of: SO_0000673
so part of: YBR036C
location: complement(<309081..>310313)
location: region:309081-310313:-1
so has part: feature:309081-310313:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:309081-310313:-1:exon

YBR036C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CLS2
gene: CSG2
locus tag: YBR036C
gene synonym: CLS2
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:7854312]
experiment: EXISTENCE:mutant phenotype:GO:0006688 glycosphingolipid biosynthetic process [PMID:8063782]
experiment: EXISTENCE:mutant phenotype:GO:0006874 cellular calcium ion homeostasis [PMID:7854312]
experiment: EXISTENCE:mutant phenotype:GO:0030234 enzyme regulator activity [PMID:12954640]
note: Endoplasmic reticulum membrane protein; required for mannosylation of inositolphosphorylceramide and for growth at high calcium concentrations; protein abundance increases in response to DNA replication stress
codon start: 1
product: mannosylinositol phosphorylceramide synthase regulatory subunit
translation: MSTTLLWFSSVIGYVIQTKCLSNIQSKKEISVGPNGTIATPETNGDNGNSSSLTFYLTFMYFASWLLLVPASRLWEKMRPMFVSDSDSNRNSQFDNNNSGSVTNEDVDTFSHVLDDPQPRIPAQQQKQKIISVATFKYVAKLTVLALIMIVADLTYNMALSLSPAFDVALMQNTAIFEIVTLLYGVCGISRKNYVFRNFLIMMNAVIGILIISYTKATCDMLAGKLSVNPNTGELSDPFLFDRLKGALICGLGALIMGPFAVLWNRWFCSNISKNENSAVVLVKQSTHMALIGIIGMVILLPFIPKFPSRESVESISLFYNDKSFWFSLLGSIIFGSLPSLISILELNRKAPAEYLTTCNLGAIIFMGLAEWVCEPTQTTIVRWEVIGYIMLTVSLLVLSVTLGEGKYHH
SIO_010081: YBR036C
subclass of: SO_0000673
so part of: YBR036C
location: complement(309081..310313)
location: region:309081-310313:-1
so has part: feature:309081-310313:-1:exon

NP_009592.1
type: Protein
SIO_000068: ncbiprotein

S000000240
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:309081-310313:-1:exon

YBR037C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PET161
gene: SCO1
locus tag: YBR037C
gene synonym: PET161
so part of: sequence
location: complement(<310565..>311452)
location: region:310565-311452:-1
so has part: feature:310565-311452:-1:exon
subclass of: SO_0000010

852325
type: Gene
SIO_000068: ncbigene

position:310565:-1
position: 310565
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:311452:-1
position: 311452
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:310565-311452:-1:exon

YBR037C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PET161
gene: SCO1
locus tag: YBR037C
gene synonym: PET161
product: Cu-binding protein SCO1
transcript id: NM_001178385.1
SIO_010081: YBR037C
subclass of: SO_0000673
so part of: YBR037C
location: complement(<310565..>311452)
location: region:310565-311452:-1
so has part: feature:310565-311452:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:310565-311452:-1:exon

YBR037C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PET161
gene: SCO1
locus tag: YBR037C
gene synonym: PET161
experiment: EXISTENCE:direct assay:GO:0005507 copper ion binding [PMID:11546815]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005743 mitochondrial inner membrane [PMID:1944230]
experiment: EXISTENCE:genetic interaction:GO:0034599 cellular response to oxidative stress [PMID:30593977]
experiment: EXISTENCE:genetic interaction:GO:0045454 cell redox homeostasis [PMID:30593977]
experiment: EXISTENCE:mutant phenotype:GO:0033617 mitochondrial cytochrome c oxidase assembly [PMID:10854440]
note: Copper-binding protein of mitochondrial inner membrane; required for cytochrome c oxidase activity and respiration; may function to deliver copper to cytochrome c oxidase; similar to thioredoxins; SCO1 has a paralog, SCO2, that arose from the whole genome duplication
codon start: 1
product: Cu-binding protein SCO1
translation: MLKLSRSANLRLVQLPAARLSGNGAKLLTQRGFFTVTRLWQSNGKKPLSRVPVGGTPIKDNGKVREGSIEFSTGKAIALFLAVGGALSYFFNREKRRLETQKEAEANRGYGKPSLGGPFHLEDMYGNEFTEKNLLGKFSIIYFGFSNCPDICPDELDKLGLWLNTLSSKYGITLQPLFITCDPARDSPAVLKEYLSDFHPSILGLTGTFDEVKNACKKYRVYFSTPPNVKPGQDYLVDHSIFFYLMDPEGQFVDALGRNYDEKTGVDKIVEHVKSYVPAEQRAKQKEAWYSFLFK
SIO_010081: YBR037C
subclass of: SO_0000673
so part of: YBR037C
location: complement(310565..311452)
location: region:310565-311452:-1
so has part: feature:310565-311452:-1:exon

NP_009593.1
type: Protein
SIO_000068: ncbiprotein

S000000241
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:310565-311452:-1:exon

YBR038W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CHS2
locus tag: YBR038W
so part of: sequence
location: <311898..>314789
location: region:311898-314789:1
so has part: feature:311898-314789:1:exon
subclass of: SO_0000010

852326
type: Gene
SIO_000068: ncbigene

position:311898:1
position: 311898
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:314789:1
position: 314789
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:311898-314789:1:exon

YBR038W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CHS2
locus tag: YBR038W
product: chitin synthase CHS2
transcript id: NM_001178386.1
SIO_010081: YBR038W
subclass of: SO_0000673
so part of: YBR038W
location: <311898..>314789
location: region:311898-314789:1
so has part: feature:311898-314789:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:311898-314789:1:exon

YBR038W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CHS2
locus tag: YBR038W
EC number: 2.4.1.16
experiment: EXISTENCE:direct assay:GO:0004100 chitin synthase activity [PMID:9990311]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:8909536|PMID:15772160]
experiment: EXISTENCE:mutant phenotype:GO:0006031 chitin biosynthetic process [PMID:22573892]
experiment: EXISTENCE:mutant phenotype:GO:1902406 mitotic actomyosin contractile ring maintenance [PMID:15772160]
note: Chitin synthase II; catalyzes transfer of N-acetylglucosamine (GlcNAc) to chitin upon activation of zymogenic form; required for chitin synthesis in the primary septum during cytokinesis; localization regulated by Cdk1p during mitosis; phosphorylation by Dbf2p kinase regulates its dynamics and chitin synthesis during cytokinesis
codon start: 1
product: chitin synthase CHS2
translation: MTRNPFMVEPSNGSPNRRGASNLSKFYANANSNSRWANPSEESLEDSYDQSNVFQGLPASPSRAALRYSPDRRHRTQFYRDSAHNSPVAPNRYAANLQESPKRAGEAVIHLSEGSNLYPRDNADLPVDPYHLSPQQQPSNNLFGSGRLYSQSSKYTMSTTSTTAPSLAEADDEKEKYLTSTTSYDDQSTIFSADTFNETKFELNHPTRQQYVRRANSESKRRMVSDLPPPSKKKALLKLDNPIPKGLLDTLPRRNSPEFTEMRYTACTVEPDDFLREGYTLRFAEMNRECQIAICITMYNEDKYSLARTIHSIMKNVAHLCKREKSHVWGPNGWKKVSVILISDGRAKVNQGSLDYLAALGVYQEDMAKASVNGDPVKAHIFELTTQVSINADLDYVSKDIVPVQLVFCLKEENKKKINSHRWLFNAFCPVLQPTVVTLVDVGTRLNNTAIYRLWKVFDMDSNVAGAAGQIKTMKGKWGLKLFNPLVASQNFEYKISNILDKPLESVFGYISVLPGALSAYRYRALKNHEDGTGPLRSYFLGETQEGRDHDVFTANMYLAEDRILCWELVAKRDAKWVLKYVKEATGETDVPEDVSEFISQRRRWLNGAMFAAIYAQLHFYQIWKTKHSVVRKFFLHVEFLYQFIQMLFSWFSIANFVLTFYYLAGSMNLVIKHGEALFIFFKYLIFCDLASLFIISMGNRPQGAKHLFITSMVILSICATYSLICGFVFAFKSLASGTESHKIFVDIVISLLSTYGLYFFSSLMYLDPWHMFTSSIQYFLTLPAFTCTLQIFAFCNTHDVSWGTKGSTQESKQLSKAIVVQGPDGKQIVETDWPQEVDKKFLEIKSRLKEPEFEESSGNEKQSKNDYYRDIRTRIVMIWMLSNLILIMSIIQVFTPQDTDNGYLIFILWSVAALAAFRVVGSMAFLFMKYLRIIVSYRNKVEGSGSWEVSKLDLPNVFHKKG
SIO_010081: YBR038W
subclass of: SO_0000673
so part of: YBR038W
location: 311898..314789
location: region:311898-314789:1
so has part: feature:311898-314789:1:exon

NP_009594.1
type: Protein
SIO_000068: ncbiprotein

S000000242
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:311898-314789:1:exon

YBR039W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ATP3
locus tag: YBR039W
so part of: sequence
location: <315575..>316510
location: region:315575-316510:1
so has part: feature:315575-316510:1:exon
subclass of: SO_0000010

852327
type: Gene
SIO_000068: ncbigene

position:315575:1
position: 315575
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:316510:1
position: 316510
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:315575-316510:1:exon

YBR039W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ATP3
locus tag: YBR039W
product: F1F0 ATP synthase subunit gamma
transcript id: NM_001178387.1
SIO_010081: YBR039W
subclass of: SO_0000673
so part of: YBR039W
location: <315575..>316510
location: region:315575-316510:1
so has part: feature:315575-316510:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:315575-316510:1:exon

YBR039W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ATP3
locus tag: YBR039W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:24769239|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005756 mitochondrial proton-transporting ATP synthase, central stalk [PMID:17082766]
experiment: EXISTENCE:direct assay:GO:0015986 proton motive force-driven ATP synthesis [PMID:20691145]
experiment: EXISTENCE:direct assay:GO:0046933 proton-transporting ATP synthase activity, rotational mechanism [PMID:20691145]
experiment: EXISTENCE:mutant phenotype:GO:0005756 mitochondrial proton-transporting ATP synthase, central stalk [PMID:7929329]
experiment: EXISTENCE:mutant phenotype:GO:0015986 proton motive force-driven ATP synthesis [PMID:7929329]
experiment: EXISTENCE:mutant phenotype:GO:0046961 proton-transporting ATPase activity, rotational mechanism [PMID:7929329]
note: Gamma subunit of the F1 sector of mitochondrial F1F0 ATP synthase; F1F0 ATP synthase is a large, evolutionarily conserved enzyme complex required for ATP synthesis
codon start: 1
product: F1F0 ATP synthase subunit gamma
translation: MLSRIVSNNATRSVMCHQAQVGILYKTNPVRTYATLKEVEMRLKSIKNIEKITKTMKIVASTRLSKAEKAKISAKKMDEAEQLFYKNAETKNLDVEATETGAPKELIVAITSDKGLCGSIHSQLAKAVRRHLNDQPNADIVTIGDKIKMQLLRTHPNNIKLSINGIGKDAPTFQESALIADKLLSVMKAGTYPKISIFYNDPVSSLSFEPSEKPIFNAKTIEQSPSFGKFEIDTDANVPRDLFEYTLANQMLTAMAQGYAAEISARRNAMDNASKNAGDMINRYSILYNRTRQAVITNELVDIITGASSLG
SIO_010081: YBR039W
subclass of: SO_0000673
so part of: YBR039W
location: 315575..316510
location: region:315575-316510:1
so has part: feature:315575-316510:1:exon

NP_009595.1
type: Protein
SIO_000068: ncbiprotein

S000000243
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:315575-316510:1:exon

YBR040W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FIG1
locus tag: YBR040W
so part of: sequence
location: <316968..>317864
location: region:316968-317864:1
so has part: feature:316968-317864:1:exon
subclass of: SO_0000010

852328
type: Gene
SIO_000068: ncbigene

position:316968:1
position: 316968
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:317864:1
position: 317864
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:316968-317864:1:exon

YBR040W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FIG1
locus tag: YBR040W
product: Fig1p
transcript id: NM_001178388.1
SIO_010081: YBR040W
subclass of: SO_0000673
so part of: YBR040W
location: <316968..>317864
location: region:316968-317864:1
so has part: feature:316968-317864:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:316968-317864:1:exon

YBR040W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FIG1
locus tag: YBR040W
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0009277 fungal-type cell wall [PMID:9456310]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:12374868]
experiment: EXISTENCE:mutant phenotype:GO:0000753 cell morphogenesis involved in conjugation with cellular fusion [PMID:9456310]
experiment: EXISTENCE:mutant phenotype:GO:0000755 cytogamy [PMID:9456310]
note: Integral membrane protein required for efficient mating; may participate in or regulate the low affinity Ca2+ influx system, which affects intracellular signaling and cell-cell fusion during mating; targeted to vacuole via AP-3 pathway
codon start: 1
product: Fig1p
translation: MVAISMIWFFTKRMPRIFALAFNLISIFLLIFLLIGCYNPSNQSTFLVKYKFDDNSPFYTIIEKSYEKSNTTLGLEEVIIRSGYMGVCIDNIPSQYSSYNNMTTFSNSICYARKNLSSVPLYRDLEIQLSNIASSSSKTQSSVVLNILKLAQLTSVNVIHPYVLMATVILTILMFLFILYVTVPKLPFKLAVNKFLLLLSSTIVLTWGIGAMWTHVGINASYRLVPSSSMNIITVKKGKKAAVMAWFSFAFLLLDSVVLWLIFLRDRKSLKDEIDNVPCAQNRYNNYSSDSSTLHSKV
SIO_010081: YBR040W
subclass of: SO_0000673
so part of: YBR040W
location: 316968..317864
location: region:316968-317864:1
so has part: feature:316968-317864:1:exon

NP_009596.1
type: Protein
SIO_000068: ncbiprotein

S000000244
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:316968-317864:1:exon

YBR041W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FAT1
locus tag: YBR041W
so part of: sequence
location: <318266..>320275
location: region:318266-320275:1
so has part: feature:318266-320275:1:exon
subclass of: SO_0000010

852329
type: Gene
SIO_000068: ncbigene

position:318266:1
position: 318266
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:320275:1
position: 320275
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:318266-320275:1:exon

YBR041W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FAT1
locus tag: YBR041W
product: long-chain fatty acid transporter FAT1
transcript id: NM_001178389.1
SIO_010081: YBR041W
subclass of: SO_0000673
so part of: YBR041W
location: <318266..>320275
location: region:318266-320275:1
so has part: feature:318266-320275:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:318266-320275:1:exon

YBR041W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FAT1
locus tag: YBR041W
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:9988704]
experiment: EXISTENCE:direct assay:GO:0005811 lipid droplet [PMID:10515935|PMID:24868093]
experiment: EXISTENCE:direct assay:GO:0009898 cytoplasmic side of plasma membrane [PMID:17679730]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0044539 long-chain fatty acid import into cell [PMID:12601005]
experiment: EXISTENCE:mutant phenotype:GO:0000038 very long-chain fatty acid metabolic process [PMID:9660783|PMID:9988704]
experiment: EXISTENCE:mutant phenotype:GO:0005324 long-chain fatty acid transporter activity [PMID:9079682]
experiment: EXISTENCE:mutant phenotype:GO:0005777 peroxisome [PMID:9660783]
experiment: EXISTENCE:mutant phenotype:GO:0006515 protein quality control for misfolded or incompletely synthesized proteins [PMID:31746669]
experiment: EXISTENCE:mutant phenotype:GO:0031957 very long-chain fatty acid-CoA ligase activity [PMID:9660783]
experiment: EXISTENCE:mutant phenotype:GO:0044539 long-chain fatty acid import into cell [PMID:10880966|PMID:12601005]
note: Very long chain fatty acyl-CoA synthetase and fatty acid transporter; activates imported fatty acids with a preference for very long lengths (C20-C26); has a separate function in the transport of long chain fatty acids
codon start: 1
product: long-chain fatty acid transporter FAT1
translation: MSPIQVVVFALSRIFLLLFRLIKLIITPIQKSLGYLFGNYFDELDRKYRYKEDWYIIPYFLKSVFCYIIDVRRHRFQNWYLFIKQVQQNGDHLAISYTRPMAEKGEFQLETFTYIETYNIVLRLSHILHFDYNVQAGDYVAIDCTNKPLFVFLWLSLWNIGAIPAFLNYNTKGTPLVHSLKISNITQVFIDPDASNPIRESEEEIKNALPDVKLNYLEEQDLMHELLNSQSPEFLQQDNVRTPLGLTDFKPSMLIYTSGTTGLPKSAIMSWRKSSVGCQVFGHVLHMTNESTVFTAMPLFHSTAALLGACAILSHGGCLALSHKFSASTFWKQVYLTGATHIQYVGEVCRYLLHTPISKYEKMHKVKVAYGNGLRPDIWQDFRKRFNIEVIGEFYAATEAPFATTTFQKGDFGIGACRNYGTIIQWFLSFQQTLVRMDPNDDSVIYRNSKGFCEVAPVGEPGEMLMRIFFPKKPETSFQGYLGNAKETKSKVVRDVFRRGDAWYRCGDLLKADEYGLWYFLDRMGDTFRWKSENVSTTEVEDQLTASNKEQYAQVLVVGIKVPKYEGRAGFAVIKLTDNSLDITAKTKLLNDSLSRLNLPSYAMPLFVKFVDEIKMTDNHKILKKVYREQKLPKGLDGNDTIFWLKNYKRYEVLTAADWEAIDAQTIKL
SIO_010081: YBR041W
subclass of: SO_0000673
so part of: YBR041W
location: 318266..320275
location: region:318266-320275:1
so has part: feature:318266-320275:1:exon

NP_009597.2
type: Protein
SIO_000068: ncbiprotein

S000000245
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:318266-320275:1:exon

YBR042C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PSI1
gene: CST26
locus tag: YBR042C
gene synonym: PSI1
so part of: sequence
location: complement(<320416..>321609)
location: region:320416-321609:-1
so has part: feature:320416-321609:-1:exon
subclass of: SO_0000010

852330
type: Gene
SIO_000068: ncbigene

position:320416:-1
position: 320416
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:321609:-1
position: 321609
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:320416-321609:-1:exon

YBR042C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PSI1
gene: CST26
locus tag: YBR042C
gene synonym: PSI1
product: putative acyltransferase
transcript id: NM_001178390.1
SIO_010081: YBR042C
subclass of: SO_0000673
so part of: YBR042C
location: complement(<320416..>321609)
location: region:320416-321609:-1
so has part: feature:320416-321609:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:320416-321609:-1:exon

YBR042C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PSI1
gene: CST26
locus tag: YBR042C
gene synonym: PSI1
experiment: EXISTENCE:direct assay:GO:0005811 lipid droplet [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0016746 acyltransferase activity [PMID:19796168|PMID:27462707]
experiment: EXISTENCE:mutant phenotype:GO:0036149 phosphatidylinositol acyl-chain remodeling [PMID:19796168|PMID:27462707]
note: Acyltransferase; enzyme mainly responsible for the introduction of saturated very long chain fatty acids into neo-synthesized molecules of phosphatidylinositol; required for incorporation of stearic acid into phosphatidylinositol; affects chromosome stability when overexpressed; CST26 has a paralog, YDR018C, that arose from the whole genome duplication
codon start: 1
product: putative acyltransferase
translation: MLHQKIAHKVRKVVVPGISLLIFFQGCLILLFLQLTYKTLYCRNDIRKQIGLNKTKRLFIVLVSSILHVVAPSAVRITTENSSVPKGTFFLDLKKKRILSHLKSNSVAICNHQIYTDWIFLWWLAYTSNLGANVFIILKKSLASIPILGFGMRNYNFIFMSRKWAQDKITLSNSLAGLDSNARGAGSLAGKSPERITEEGESIWNPEVIDPKQIHWPYNLILFPEGTNLSADTRQKSAKYAAKIGKKPFKNVLLPHSTGLRYSLQKLKPSIESLYDITIGYSGVKQEEYGELIYGLKSIFLEGKYPKLVDIHIRAFDVKDIPLEDENEFSEWLYKIWSEKDALMERYYSTGSFVSDPETNHSVTDSFKINRIELTEVLILPTLTIIWLVYKLYCFIF
SIO_010081: YBR042C
subclass of: SO_0000673
so part of: YBR042C
location: complement(320416..321609)
location: region:320416-321609:-1
so has part: feature:320416-321609:-1:exon

NP_009598.1
type: Protein
SIO_000068: ncbiprotein

S000000246
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:320416-321609:-1:exon

YBR043C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: AQR2
gene: QDR3
locus tag: YBR043C
gene synonym: AQR2
so part of: sequence
location: complement(<321876..>323945)
location: region:321876-323945:-1
so has part: feature:321876-323945:-1:exon
subclass of: SO_0000010

852331
type: Gene
SIO_000068: ncbigene

position:321876:-1
position: 321876
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:323945:-1
position: 323945
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:321876-323945:-1:exon

YBR043C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: AQR2
gene: QDR3
locus tag: YBR043C
gene synonym: AQR2
product: Qdr3p
transcript id: NM_001178391.2
SIO_010081: YBR043C
subclass of: SO_0000673
so part of: YBR043C
location: complement(<321876..>323945)
location: region:321876-323945:-1
so has part: feature:321876-323945:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:321876-323945:-1:exon

YBR043C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: AQR2
gene: QDR3
locus tag: YBR043C
gene synonym: AQR2
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:15649438|PMID:34887841]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0030476 ascospore wall assembly [PMID:23966878]
experiment: EXISTENCE:mutant phenotype:GO:0010509 polyamine homeostasis [PMID:21148207]
experiment: EXISTENCE:mutant phenotype:GO:0015203 polyamine transmembrane transporter activity [PMID:21148207]
experiment: EXISTENCE:mutant phenotype:GO:0015562 efflux transmembrane transporter activity [PMID:15649438]
experiment: EXISTENCE:mutant phenotype:GO:0015565 threonine efflux transmembrane transporter activity [PMID:34887841]
experiment: EXISTENCE:mutant phenotype:GO:0032973 amino acid export across plasma membrane [PMID:34887841]
experiment: EXISTENCE:mutant phenotype:GO:0055085 transmembrane transport [PMID:15649438]
note: Multidrug transporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; has a role in polyamine homeostasis; involved in spore wall asembly; sequence similarity to DTR1 and QDR1, and the triple mutant dtr1 qdr1 qdr3 exhibits reduced dityrosine fluorescence relative to the single mutants; expression is upregulated under polyamine stress; required for resistance to quinidine, barban, cisplatin, and bleomycin
codon start: 1
product: Qdr3p
translation: MQAQGSQSNVGSLRSNCSDNSLPNNHVMMHCDESSGSPHSEHNDYSYEKTNLESTASNSREHRDNQLSRLKSEEYVVPKNQRRGLLPQLAIIPEFKDARDYPPMMKKMIVFLIAFSSMMGPMGTSIIFPAINSITTEFKTSVIMVNVSIGVYLLSLGVFPLWWSSLSELEGRRTTYITSFALLFAFNIGSALAPDINSFIALRMLCGAASASVQSVGAGTVADLYISEDRGKNLSYYYLGPLLAPLLSPIFGSLLVNRWPWRSTQWFMVILSGCNVILLTVLLPETLRKQDSKGAIAQILAERRIQVDNNERGEIQEDYQRGEDETDRIENQVATLSTEKHNYVGEVRDQDSLDLESHSSPNTYDGRAGETQLQRIYTEASRSLYEYQLDDSGIDATTAQVTRIRSTDPKLARSIRENSLRKLQTNLEEQVKKVLSSNGGEIAPKQVSAVRKVWDTFFVYFIKPLKSLHFLEYPPVALAITFSAISFSTVYFVNMTVEYKYSRPPYNFKPLYIGLLYIPNSVTYFFASIYGGRWVDMLLKRYKEKYGILAPEARISWNVVTSVISFPIALLIFGWCLDKKCHWVTPLIGTALFGYAAMMTIGATLSYLVDSLPGKGATGVALNNLIRQILAATAVFVTTPMLNGMGTGWAFTMLAFIVLGASSVLIILKKHGDYWRENYDLQKLYDKID
SIO_010081: YBR043C
subclass of: SO_0000673
so part of: YBR043C
location: complement(321876..323945)
location: region:321876-323945:-1
so has part: feature:321876-323945:-1:exon

NP_009599.2
type: Protein
SIO_000068: ncbiprotein

S000000247
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:321876-323945:-1:exon

YBR044C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TCM62
locus tag: YBR044C
so part of: sequence
location: complement(<324341..>326059)
location: region:324341-326059:-1
so has part: feature:324341-326059:-1:exon
subclass of: SO_0000010

852332
type: Gene
SIO_000068: ncbigene

position:324341:-1
position: 324341
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:326059:-1
position: 326059
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:324341-326059:-1:exon

YBR044C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TCM62
locus tag: YBR044C
product: Tcm62p
transcript id: NM_001178392.2
SIO_010081: YBR044C
subclass of: SO_0000673
so part of: YBR044C
location: complement(<324341..>326059)
location: region:324341-326059:-1
so has part: feature:324341-326059:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:324341-326059:-1:exon

YBR044C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TCM62
locus tag: YBR044C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005743 mitochondrial inner membrane [PMID:9822678]
experiment: EXISTENCE:mutant phenotype:GO:0034553 mitochondrial respiratory chain complex II assembly [PMID:9822678]
note: Protein involved in assembly of the succinate dehydrogenase complex; mitochondrial; putative chaperone
codon start: 1
product: Tcm62p
translation: MLRNCLRKLGNHQTKCSVKTLHTPIYRTKNLQVLRDTLSGIKLLEKIITSSSYNKTLIYEPKYKSKPQVVSSHDTMRLHNVMRELLDSLQVDEATNTRLQSNRPRKLGRVGLQLFMDCIQDNLTATSTSLTCSLLEHYFKYPEKEVTNGIKAGLRYIRDFLAKNKIIVKSQNDVDALVEQLTMSSSDSQSIKRVLKAINYELFSDDIVRVINGNKTYDEVDVSKGWKYPAGILDSNEAYLRSLELPTKKLVSIDKDMLVLMYDGTLRDANKILPTITYARKLRKSVLLIVNGDCTGDALTSVTINNNRNKRENNESRIVVLKYSKKANNDLAPQENLDFIKFLRLPCGYDSIYSPEYSPLVPSKMCADKYYGSIESIKATTGEAFLYNSIDAEAIPNKVPKSFLQNTVTLSIGGHNEIEIDRRRNAIDNCLNNVLCHGLAKGFIPGYGISLLKAIPGLNELKANEPNFMTKVGINAVLSAVILPSEVAFKNAYGYNYYEINSLIAGAINEKSFPMAKFSPNSEPVNTVKDGNLEPWSKMDSCLAGVETFIELLTSCNTIITCVYKKPERHKA
SIO_010081: YBR044C
subclass of: SO_0000673
so part of: YBR044C
location: complement(324341..326059)
location: region:324341-326059:-1
so has part: feature:324341-326059:-1:exon

NP_009600.2
type: Protein
SIO_000068: ncbiprotein

S000000248
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:324341-326059:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS211; Autonomously Replicating Sequence
so part of: sequence
location: 326140..326375
location: region:326140-326375:1
so has part: feature:326140-326375:1:region

S000118347
type: SGD
SIO_000068: sgd

position:326140:1
position: 326140
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:326375:1
position: 326375
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:326140-326375:1:region

YNCB0011C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCB0011C
so part of: sequence
location: complement(326792..326865)
location: region:326792-326865:-1
so has part: feature:326792-326865:-1:exon
subclass of: SO_0000663

852333
type: Gene
SIO_000068: ncbigene

position:326792:-1
position: 326792
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:326865:-1
position: 326865
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:326792-326865:-1:exon

YNCB0011C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCB0011C
product: tRNA-Val
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Valine tRNA (tRNA-Val), predicted by tRNAscan-SE analysis
SIO_010081: YNCB0011C
subclass of: SO_0000673
so part of: YNCB0011C
location: complement(326792..326865)
location: region:326792-326865:-1
so has part: feature:326792-326865:-1:exon

S000006769
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:326792-326865:-1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 327069..327394
location: region:327069-327394:1
so has part: feature:327069-327394:1:region

S000006817
type: SGD
SIO_000068: sgd

position:327069:1
position: 327069
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:327394:1
position: 327394
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:327069-327394:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 327390..327704
location: region:327390-327704:1
so has part: feature:327390-327704:1:region

S000006818
type: SGD
SIO_000068: sgd

position:327390:1
position: 327390
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:327704:1
position: 327704
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:327390-327704:1:region

YBR045C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GIP1
locus tag: YBR045C
so part of: sequence
location: complement(<328173..>330092)
location: region:328173-330092:-1
so has part: feature:328173-330092:-1:exon
subclass of: SO_0000010

852334
type: Gene
SIO_000068: ncbigene

position:328173:-1
position: 328173
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:330092:-1
position: 330092
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:328173-330092:-1:exon

YBR045C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GIP1
locus tag: YBR045C
product: protein phosphatase regulator GIP1
transcript id: NM_001178393.2
SIO_010081: YBR045C
subclass of: SO_0000673
so part of: YBR045C
location: complement(<328173..>330092)
location: region:328173-330092:-1
so has part: feature:328173-330092:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:328173-330092:-1:exon

YBR045C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GIP1
locus tag: YBR045C
experiment: EXISTENCE:direct assay:GO:0005628 prospore membrane [PMID:11724821]
experiment: EXISTENCE:direct assay:GO:0019888 protein phosphatase regulator activity [PMID:11724821]
experiment: EXISTENCE:mutant phenotype:GO:0008157 protein phosphatase 1 binding [PMID:9584086]
experiment: EXISTENCE:mutant phenotype:GO:0030476 ascospore wall assembly [PMID:11724821]
experiment: EXISTENCE:mutant phenotype:GO:0043666 regulation of phosphoprotein phosphatase activity [PMID:11724821]
experiment: EXISTENCE:physical interaction:GO:0000164 protein phosphatase type 1 complex [PMID:9584086]
note: Meiosis-specific regulatory subunit of the Glc7p protein phosphatase; regulates spore wall formation and septin organization, required for expression of some late meiotic genes and for normal localization of Glc7p
codon start: 1
product: protein phosphatase regulator GIP1
translation: METILQPKARPFESLKRKRFREWLRPSTAHGSLLHSDTLDLRDFAKPNPADTFSNLDSGHCPLVTTPIKYECPDGKSSFFRGDTKFETLFSNRKFYEFKDNLKRGLKKIRHGRNGHQSEKRCPVVEETKKSVSDNLDKPDNNTPCFDRFHTNSKEFETQFDHSNRSQNSEKAYLDNESCWNLSEKFIPFNNLKYEDLKHFEENLQSLAPATFTPIESNESLDRSDSTRGTKRSIRNDSSDTTSEKRLCLKQYSDEPESDHSMESTPSIYITKEVQERIEALSSTDSFLIEKVDFPSNKIGSSASDYESDNEYRNMDEDSINDVTTEKEGNVVIPDSNTSTVDAMEKPIEVSSALKDDTLDKDIDDASSSYSDDVETTFEPVESEELSDLSDTSSSGSSKIYTIPTFRGLTNRTNISQILSKVGKADLSQDNLTHLIKSHQKKKRCVNFRNKRFYDAFNPYVDNEEDAELSDSENISEMDTDLCIKDRSTSSVRFDENSRLLIYKKSKKLNKDETQSGYSTTEMRSILKTKMNSQHDEESQRASKCDTVGVAQFLHYFQYTEYKRQRNEAENYRLRGEQLSKYYSEEYPLDFAAVECEDSVNDKSDIILSMRATERNIGRQLKGISSQGAQIISLDEDVF
SIO_010081: YBR045C
subclass of: SO_0000673
so part of: YBR045C
location: complement(328173..330092)
location: region:328173-330092:-1
so has part: feature:328173-330092:-1:exon

NP_009601.2
type: Protein
SIO_000068: ncbiprotein

S000000249
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:328173-330092:-1:exon

YBR046C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ZTA1
locus tag: YBR046C
so part of: sequence
location: complement(<330507..>331511)
location: region:330507-331511:-1
so has part: feature:330507-331511:-1:exon
subclass of: SO_0000010

852335
type: Gene
SIO_000068: ncbigene

position:330507:-1
position: 330507
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:331511:-1
position: 331511
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:330507-331511:-1:exon

YBR046C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ZTA1
locus tag: YBR046C
product: NADPH:quinone reductase
transcript id: NM_001178394.1
SIO_010081: YBR046C
subclass of: SO_0000673
so part of: YBR046C
location: complement(<330507..>331511)
location: region:330507-331511:-1
so has part: feature:330507-331511:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:330507-331511:-1:exon

YBR046C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ZTA1
locus tag: YBR046C
EC number: 1.6.5.5
experiment: EXISTENCE:direct assay:GO:0003960 NADPH:quinone reductase activity [PMID:17497241]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0032440 2-alkenal reductase [NAD(P)+] activity [PMID:21276778]
experiment: EXISTENCE:direct assay:GO:0035925 mRNA 3'-UTR AU-rich region binding [PMID:17497241|PMID:19007762]
experiment: EXISTENCE:mutant phenotype:GO:0034599 cellular response to oxidative stress [PMID:17497241]
note: NADPH-dependent quinone reductase; GFP-tagged protein localizes to the cytoplasm and nucleus; has similarity to E. coli quinone oxidoreductase and to human zeta-crystallin
codon start: 1
product: NADPH:quinone reductase
translation: MKCTIPEQQKVILIDEIGGYDVIKYEDYPVPSISEEELLIKNKYTGVNYIESYFRKGIYPCEKPYVLGREASGTVVAKGKGVTNFEVGDQVAYISNSTFAQYSKISSQGPVMKLPKGTSDEELKLYAAGLLQVLTALSFTNEAYHVKKGDYVLLFAAAGGVGLILNQLLKMKGAHTIAVASTDEKLKIAKEYGAEYLINASKEDILRQVLKFTNGKGVDASFDSVGKDTFEISLAALKRKGVFVSFGNASGLIPPFSITRLSPKNITLVRPQLYGYIADPEEWKYYSDEFFGLVNSKKLNIKIYKTYPLRDYRTAAADIESRKTVGKLVLEIPQ
SIO_010081: YBR046C
subclass of: SO_0000673
so part of: YBR046C
location: complement(330507..331511)
location: region:330507-331511:-1
so has part: feature:330507-331511:-1:exon

NP_009602.1
type: Protein
SIO_000068: ncbiprotein

S000000250
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:330507-331511:-1:exon

YBR047W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FMP23
locus tag: YBR047W
so part of: sequence
location: <331833..>332360
location: region:331833-332360:1
so has part: feature:331833-332360:1:exon
subclass of: SO_0000010

852336
type: Gene
SIO_000068: ncbigene

position:331833:1
position: 331833
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:332360:1
position: 332360
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:331833-332360:1:exon

YBR047W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FMP23
locus tag: YBR047W
product: Fmp23p
transcript id: NM_001178395.1
SIO_010081: YBR047W
subclass of: SO_0000673
so part of: YBR047W
location: <331833..>332360
location: region:331833-332360:1
so has part: feature:331833-332360:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:331833-332360:1:exon

YBR047W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FMP23
locus tag: YBR047W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095|PMID:14576278|PMID:16823961]
note: hypothetical protein; proposed to be involved in iron or copper homeostasis; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
codon start: 1
product: Fmp23p
translation: MLINHLSKIRTVRHFSNIKPVLSKEVSRRVIVAPASHFKTSSPNVKSNIPIHEYKQLPEDSNYIEKHYKELQVFLNEFLIKKLNKTYADFEGDPDELVFQLEKFIELEVTPRYTNHSAPDGCEERFKSIGDRIVVDRYLDFVKDVRLTLLLNGGHSFIFDVMLQAKEVFDKMQKE
SIO_010081: YBR047W
subclass of: SO_0000673
so part of: YBR047W
location: 331833..332360
location: region:331833-332360:1
so has part: feature:331833-332360:1:exon

NP_009603.1
type: Protein
SIO_000068: ncbiprotein

S000000251
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:331833-332360:1:exon

YBR048W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RPS11B
locus tag: YBR048W
so part of: sequence
location: <332831..>333812
location: region:332831-333812:1
so has part: feature:332831-333812:1:exon
subclass of: SO_0000010

852337
type: Gene
SIO_000068: ncbigene

position:332831:1
position: 332831
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:333812:1
position: 333812
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:332831-333812:1:exon

YBR048W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RPS11B
locus tag: YBR048W
product: ribosomal 40S subunit protein S11B
transcript id: NM_001178396.1
SIO_010081: YBR048W
subclass of: SO_0000673
so part of: YBR048W
location: join(<332831..332875,333387..>333812)
location: region:332831-333812:1
so has part: feature:332831-332875:1:exon
so has part: feature:333387-333812:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:332831-332875:1:exon

position:332875:1
position: 332875
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:333387-333812:1:exon

position:333387:1
position: 333387
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YBR048W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RPS11B
locus tag: YBR048W
experiment: EXISTENCE:curator inference:GO:0002181 cytoplasmic translation [PMID:6814480]
experiment: EXISTENCE:direct assay:GO:0003735 structural constituent of ribosome [PMID:6814480]
experiment: EXISTENCE:direct assay:GO:0022627 cytosolic small ribosomal subunit [PMID:6814480]
experiment: EXISTENCE:direct assay:GO:0030686 90S preribosome [PMID:12150911]
experiment: EXISTENCE:genetic interaction:GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:16246728]
experiment: EXISTENCE:mutant phenotype:GO:0000028 ribosomal small subunit assembly [PMID:8070651]
note: Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S11 and bacterial S17; RPS11B has a paralog, RPS11A, that arose from the whole genome duplication
codon start: 1
product: ribosomal 40S subunit protein S11B
translation: MSTELTVQSERAFQKQPHIFNNPKVKTSKRTKRWYKNAGLGFKTPKTAIEGSYIDKKCPFTGLVSIRGKILTGTVVSTKMHRTIVIRRAYLHYIPKYNRYEKRHKNVPVHVSPAFRVQVGDIVTVGQCRPISKTVRFNVVKVSAAAGKANKQFAKF
SIO_010081: YBR048W
subclass of: SO_0000673
so part of: YBR048W
location: join(332831..332875,333387..333812)
location: region:332831-333812:1
so has part: feature:332831-332875:1:exon
so has part: feature:333387-333812:1:exon

NP_009604.1
type: Protein
SIO_000068: ncbiprotein

S000000252
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:332831-332875:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:333387-333812:1:exon

YBR049C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: EBF1
alternative label: GRF2
gene: REB1
locus tag: YBR049C
gene synonym: EBF1; GRF2
so part of: sequence
location: complement(<334386..>336818)
location: region:334386-336818:-1
so has part: feature:334386-336818:-1:exon
subclass of: SO_0000010

852338
type: Gene
SIO_000068: ncbigene

position:334386:-1
position: 334386
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:336818:-1
position: 336818
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:334386-336818:-1:exon

YBR049C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: EBF1
alternative label: GRF2
gene: REB1
locus tag: YBR049C
gene synonym: EBF1; GRF2
product: DNA-binding protein REB1
transcript id: NM_001178397.1
SIO_010081: YBR049C
subclass of: SO_0000673
so part of: YBR049C
location: complement(<334386..>336818)
location: region:334386-336818:-1
so has part: feature:334386-336818:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:334386-336818:-1:exon

YBR049C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: EBF1
alternative label: GRF2
gene: REB1
locus tag: YBR049C
gene synonym: EBF1; GRF2
experiment: EXISTENCE:direct assay:GO:0001174 transcriptional start site selection at RNA polymerase II promoter [PMID:27601258]
experiment: EXISTENCE:direct assay:GO:0005654 nucleoplasm [PMID:20852627]
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:25479637|PMID:27601258]
experiment: EXISTENCE:mutant phenotype:GO:0001174 transcriptional start site selection at RNA polymerase II promoter [PMID:27601258]
experiment: EXISTENCE:mutant phenotype:GO:0006357 regulation of transcription by RNA polymerase II [PMID:27601258]
experiment: EXISTENCE:mutant phenotype:GO:0006369 termination of RNA polymerase II transcription [PMID:25479637]
note: RNA polymerase I enhancer binding protein; DNA binding protein that binds to genes transcribed by both RNA polymerase I and RNA polymerase II; required for termination of RNA polymerase I transcription; Reb1p bound to DNA acts to block RNA polymerase II readthrough transcription
codon start: 1
product: DNA-binding protein REB1
translation: MPSGHNDKNANQESVEEAVLKYVGVGLDHQNHDPQLHTKDLENKHSKKQNIVESSSDVDVNNNDDSNRNEDNNDDSENISALNANESSSNVDHANSNEQHNAVMDWYLRQTAHNQQDDEDDENNNNTDNGNDSNNHFSQSDIVVDDDDDKNKKDAGVGVDDDHQSMAMAAVAAAYTLSKNNNNNNSIANDSNSRKRQHDNGNNHENSQKKRKNNNDDDDRQIGNVDPELTTLGDADDNDTNNDVIDRDQLVHKAIIDADSITQHPDFQQYLNTAADTDDNEKLKHIKDHLMRTHGLNHQNKNHNDDTDDLSNSTKQYSELQKDSMLDSSLNKSRNYMEVLPKVISQDTQPHQQKSPSHDNEAGSVDNSEISQLLQSAATKASSLVSLSSSSATPSTSRSNNSKAFDKAEDAALERFINEYEAIERLTRQQVCERIWSSDRPKDNFWNNIYKVLPYRSSSSIYKHMRRKYHIFEQRGKWTAEEEQELAKLCAEKEGQWAEIGKTLGRMPEDCRDRWRNYVKCGTNRASNRWSVEEEELLKKVISDMLEEAQQQQSQLHPNLLEEEQHLLQDDQNDHRNNDEDDDDTASAAAAAAAAIQEQQQLLQQKQQDDDDAIAAAAAAASSSLGDNKDEDKPHDSLGIQLDDNSQNSMVPAPSATSTHSKSLSNTIRRHNNKLRKSLMGNGKLDFKDIINWTIVSERMGGTRSRIQCRYKWNKLVKREAIAKIQTVKDDDMLWIFEKLRDLGITEDSQVDWDELAALKPGMKLNGLELKLCYERMKKKVKGYKQKSINEISKELVDYFSSNISMKTEN
SIO_010081: YBR049C
subclass of: SO_0000673
so part of: YBR049C
location: complement(334386..336818)
location: region:334386-336818:-1
so has part: feature:334386-336818:-1:exon

NP_009605.1
type: Protein
SIO_000068: ncbiprotein

S000000253
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:334386-336818:-1:exon

YBR050C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: REG2
locus tag: YBR050C
so part of: sequence
location: complement(<337183..>338199)
location: region:337183-338199:-1
so has part: feature:337183-338199:-1:exon
subclass of: SO_0000010

852340
type: Gene
SIO_000068: ncbigene

position:337183:-1
position: 337183
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:338199:-1
position: 338199
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:337183-338199:-1:exon

YBR050C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: REG2
locus tag: YBR050C
product: protein phosphatase regulator REG2
transcript id: NM_001178398.1
SIO_010081: YBR050C
subclass of: SO_0000673
so part of: YBR050C
location: complement(<337183..>338199)
location: region:337183-338199:-1
so has part: feature:337183-338199:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:337183-338199:-1:exon

YBR050C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: REG2
locus tag: YBR050C
experiment: EXISTENCE:direct assay:GO:0019888 protein phosphatase regulator activity [PMID:8649403]
experiment: EXISTENCE:mutant phenotype:GO:0043666 regulation of phosphoprotein phosphatase activity [PMID:8649403]
experiment: EXISTENCE:physical interaction:GO:0000164 protein phosphatase type 1 complex [PMID:8649403]
note: Regulatory subunit of the Glc7p type-1 protein phosphatase; involved with Reg1p, Glc7p, and Snf1p in regulation of glucose-repressible genes, also involved in glucose-induced proteolysis of maltose permease; REG2 has a paralog, REG1, that arose from the whole genome duplication
codon start: 1
product: protein phosphatase regulator REG2
translation: MTLSNCDSLDNLFQDPPEEEESSKFVEAVRTLMNRNDMGYPPAAANGTYCLKKIKSLNAKQWKINKKRMCMLPAVKKKNFDFHEQRSLILNLNLWKFIKFINCSSKNNYNKNNKHVRSSNNTVKNENVLPLQKHKKVDNDQRLENLFWRSWFKARKRRDIMGKPRERHIKFNDNVEQCIITDEHFIQRLPSTRLNSTDEQRPCSKSELDPCIGNAASKRSFYDYNSVYVASDAIITTAAATAIISSNSGDYQRGHDVRDVPRNVLLQAGETDFSSVLRVDSDLKLSNISHHSPVKPSSTSSHSTFIFESETDTDTDTDAETENDIDAYIDTSIPNLLL
SIO_010081: YBR050C
subclass of: SO_0000673
so part of: YBR050C
location: complement(337183..338199)
location: region:337183-338199:-1
so has part: feature:337183-338199:-1:exon

NP_009606.1
type: Protein
SIO_000068: ncbiprotein

S000000254
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:337183-338199:-1:exon

YBR052C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RFS1
locus tag: YBR052C
so part of: sequence
location: complement(<338720..>339352)
location: region:338720-339352:-1
so has part: feature:338720-339352:-1:exon
subclass of: SO_0000010

852341
type: Gene
SIO_000068: ncbigene

position:338720:-1
position: 338720
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:339352:-1
position: 339352
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:338720-339352:-1:exon

YBR052C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RFS1
locus tag: YBR052C
product: flavodoxin-like fold family protein
transcript id: NM_001178400.1
SIO_010081: YBR052C
subclass of: SO_0000673
so part of: YBR052C
location: complement(<338720..>339352)
location: region:338720-339352:-1
so has part: feature:338720-339352:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:338720-339352:-1:exon

YBR052C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RFS1
locus tag: YBR052C
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:21442317|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0032126 eisosome [PMID:19064668]
note: hypothetical protein; member of a flavodoxin-like fold protein family that includes Pst2p and Ycp4p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; RFS1 has a paralog, PST2, that arose from the whole genome duplication
codon start: 1
product: flavodoxin-like fold family protein
translation: MPKVAILIYSVDDIIATLAENEKKGIEIAGGEAEIFQVPDVSYKTEYATEEGKEAAKVAKTNADFSYKILTRETLVEYDYYLFGIPTKFGNFPAEWKSFWDSNTGGLWAKGSLHGKIAGLFVSGAISGKGDTEMCIMNAMSTLVHHGVIYVPLGYKNAYKELTDVEDVNGSCAWGAGCVSGIDGGRPPSLSELRVHQLQGKAFYDRIKDL
SIO_010081: YBR052C
subclass of: SO_0000673
so part of: YBR052C
location: complement(338720..339352)
location: region:338720-339352:-1
so has part: feature:338720-339352:-1:exon

NP_009608.1
type: Protein
SIO_000068: ncbiprotein

S000000256
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:338720-339352:-1:exon

YBR053C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBR053C
so part of: sequence
location: complement(<339675..>340751)
location: region:339675-340751:-1
so has part: feature:339675-340751:-1:exon
subclass of: SO_0000010

852342
type: Gene
SIO_000068: ncbigene

position:339675:-1
position: 339675
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:340751:-1
position: 340751
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:339675-340751:-1:exon

YBR053C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBR053C
product: uncharacterized protein
transcript id: NM_001178401.1
SIO_010081: YBR053C
subclass of: SO_0000673
so part of: YBR053C
location: complement(<339675..>340751)
location: region:339675-340751:-1
so has part: feature:339675-340751:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:339675-340751:-1:exon

YBR053C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBR053C
note: hypothetical protein; induced by cell wall perturbation
codon start: 1
product: uncharacterized protein
translation: MSSVGDFEEIILHDLKPYYHVPGAIHSEGITFVKETGTLLWVDIFKGEVHKVEDIEQPESSHSFFSISRANYGKNASIEYPPNPDELKESVGCIFPILDGASQNEIKQVLFGSKFGIGKLDFSKSEWEYVILYSECPELSTDRAYKLRSNDGNVSPDGKYIYVGLMSDFPFDLEPIGCLLRVDLLAHKIELVWNCLLIPNAIHWDESDQKTMYVTDSLNFTIWKCPGGDLLKRDELIDVKNSNNQSFESPEPDGSAIWFSKDGKHSGFLFITVWSTSKVQMFDLTNGKLLKEFILPEQTPRVSCCCFVGKDLFVTTANAEINDAVRTNTDKNGGCIYKIPNVLDGNVPLESTKRQPLH
SIO_010081: YBR053C
subclass of: SO_0000673
so part of: YBR053C
location: complement(339675..340751)
location: region:339675-340751:-1
so has part: feature:339675-340751:-1:exon

NP_009609.1
type: Protein
SIO_000068: ncbiprotein

S000000257
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:339675-340751:-1:exon

YBR054W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: YRO2
locus tag: YBR054W
so part of: sequence
location: <343101..>344135
location: region:343101-344135:1
so has part: feature:343101-344135:1:exon
subclass of: SO_0000010

852343
type: Gene
SIO_000068: ncbigene

position:343101:1
position: 343101
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:344135:1
position: 344135
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:343101-344135:1:exon

YBR054W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: YRO2
locus tag: YBR054W
product: Yro2p
transcript id: NM_001178402.1
SIO_010081: YBR054W
subclass of: SO_0000673
so part of: YBR054W
location: <343101..>344135
location: region:343101-344135:1
so has part: feature:343101-344135:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:343101-344135:1:exon

YBR054W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: YRO2
locus tag: YBR054W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:25503505]
experiment: EXISTENCE:direct assay:GO:0005933 cellular bud [PMID:14562095]
note: Protein with a putative role in response to acid stress; null mutant is sensitive to acetic acid; transcription is regulated by Haa1p and induced in the presence of acetic acid; protein observed in plasma membrane foci in the presence of acetic acid; the authentic, non-tagged protein is detected in a phosphorylated state in highly purified mitochondria in high-throughput studies
codon start: 1
product: Yro2p
translation: MSDYVELLKRGGNEAIKINPPTGADFHITSRGSDWLFTVFCVNLLFGVILVPLMFRKPVKDRFVYYTAIAPNLFMSIAYFTMASNLGWIPVRAKYNHVQTSTQKEHPGYRQIFYARYVGWFLAFPWPIIQMSLLGGTPLWQIAFNVGMTEIFTVCWLIAACVHSTYKWGYYTIGIGAAIVVCISLMTTTFNLVKARGKDVSNVFITFMSVIMFLWLIAYPTCFGITDGGNVLQPDSATIFYGIIDLLILSILPVLFMPLANYLGIERLGLIFDEEPAEHVGPVAEKKMPSPASFKSSDSDSSIKEKLKLKKKHKKDKKKAKKAKKAKKAKKAQEEEEDVATDSE
SIO_010081: YBR054W
subclass of: SO_0000673
so part of: YBR054W
location: 343101..344135
location: region:343101-344135:1
so has part: feature:343101-344135:1:exon

NP_009610.1
type: Protein
SIO_000068: ncbiprotein

S000000258
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:343101-344135:1:exon

YBR055C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RNA6
alternative label: TSM7269
gene: PRP6
locus tag: YBR055C
gene synonym: RNA6; TSM7269
so part of: sequence
location: complement(<344602..>347301)
location: region:344602-347301:-1
so has part: feature:344602-347301:-1:exon
subclass of: SO_0000010

852344
type: Gene
SIO_000068: ncbigene

position:344602:-1
position: 344602
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:347301:-1
position: 347301
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:344602-347301:-1:exon

YBR055C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RNA6
alternative label: TSM7269
gene: PRP6
locus tag: YBR055C
gene synonym: RNA6; TSM7269
product: U4/U6-U5 snRNP complex subunit PRP6
transcript id: NM_001178403.1
SIO_010081: YBR055C
subclass of: SO_0000673
so part of: YBR055C
location: complement(<344602..>347301)
location: region:344602-347301:-1
so has part: feature:344602-347301:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:344602-347301:-1:exon

YBR055C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RNA6
alternative label: TSM7269
gene: PRP6
locus tag: YBR055C
gene synonym: RNA6; TSM7269
experiment: EXISTENCE:direct assay:GO:0046540 U4/U6 x U5 tri-snRNP complex [PMID:10377396|PMID:10449419|PMID:8479905]
experiment: EXISTENCE:direct assay:GO:0071001 U4/U6 snRNP [PMID:8479905]
experiment: EXISTENCE:mutant phenotype:GO:0000398 mRNA splicing, via spliceosome [PMID:2147224]
experiment: EXISTENCE:mutant phenotype:GO:0071001 U4/U6 snRNP [PMID:2147224]
note: Splicing factor; component of the U4/U6-U5 snRNP complex
codon start: 1
product: U4/U6-U5 snRNP complex subunit PRP6
translation: MERPSFLDQEPPAGYVPGIGRGATGFSTKEKQVVSNDDKGRRIPKRYRENLNNHLQSQPKDDEDDEAANVFKTLELKLAQKKKKRANEKDDDNSVDSSNVKRQFADLKESLAAVTESEWMDIPDATDFTRRNKRNRIQEQLNRKTYAAPDSLIPGNVDLNKLTEEREKLLQSQIDENLAQLTKNASNPIQVNKPNAATDALSYLKDLENDRVNSLSDATLEDLQKMRTILKSYRKADPTNPQGWIASARLEEKARKFSVAKKIIENGCQECPRSSDIWLENIRLHESDVHYCKTLVATAINFNPTSPLLWFKAIDLESTTVNKYRVVRKALQEIPRDEGLWKLAVSFEADKAQVIKMLEKATQFIPQSMDLLTAYTNLQSYHNAKMTLNSFRKILPQEPEIWIISTLLEERNNPDIPVDKLVSLLKEGLLELSKNGYKATLSAWLKRAEALNDAPNSNLTCQAIVYAILEWLRESGEYESELNNVDQILEKMPHSKVQIAVLKKLIQWDPCDTVLWSRLKMATESYHKIEELLAFFQELLFQTKNSDDIRANMREKSPGLLMMYVSEYWKAQKGDTRQTLVLIDQIIDFAPHNLDLRFFKIKLLGRSLQLDELRDFFQQTFSSLEDFKISGTERLYYKYVNFLRYQDLNEEAIKFLNERCLKSFPICHKFFLQLGQIYHSMGNIEMSRETYLSGTRLVPNCPLLWVSLSKIDEIDLKNPVRARSILDRGLLKNPDDVLFYIAKIQMEIRLGNLDQAELLVTQALQKFPSNALLWVEQIKLFKHGNKSSLKKTIFQDALRRTQNDHRVLLEIGVSFYAEAQYETSLKWLERALKKCSRYGDTWVWLFRTYARLGKDTVDLYNMFDQCEPTYGPEWIAASKNVKMQYCTPREILLRLMNDK
SIO_010081: YBR055C
subclass of: SO_0000673
so part of: YBR055C
location: complement(344602..347301)
location: region:344602-347301:-1
so has part: feature:344602-347301:-1:exon

NP_009611.1
type: Protein
SIO_000068: ncbiprotein

S000000259
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:344602-347301:-1:exon

YNCB0012W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCB0012W
so part of: sequence
location: 347603..347686
location: region:347603-347686:1
so has part: feature:347603-347686:1:exon
subclass of: SO_0000663

852345
type: Gene
SIO_000068: ncbigene

position:347603:1
position: 347603
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:347686:1
position: 347686
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:347603-347686:1:exon

YNCB0012W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCB0012W
product: tRNA-Leu
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
experiment: EXISTENCE:direct assay:GO:0030371 translation repressor activity [PMID:27609601]
experiment: EXISTENCE:direct assay:GO:0043022 ribosome binding [PMID:27609601]
experiment: EXISTENCE:direct assay:GO:0043555 regulation of translation in response to stress [PMID:27609601]
note: Leucine tRNA (tRNA-Leu), predicted by tRNAscan-SE analysis
SIO_010081: YNCB0012W
subclass of: SO_0000673
so part of: YNCB0012W
location: 347603..347686
location: region:347603-347686:1
so has part: feature:347603-347686:1:exon

S000006648
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:347603-347686:1:exon

YBR056W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MRX18
locus tag: YBR056W
so part of: sequence
location: <347879..>349384
location: region:347879-349384:1
so has part: feature:347879-349384:1:exon
subclass of: SO_0000010

852346
type: Gene
SIO_000068: ncbigene

position:347879:1
position: 347879
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:349384:1
position: 349384
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:347879-349384:1:exon

YBR056W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MRX18
locus tag: YBR056W
product: 17-beta-hydroxysteroid dehydrogenase-like protein
transcript id: NM_001178404.1
SIO_010081: YBR056W
subclass of: SO_0000673
so part of: YBR056W
location: <347879..>349384
location: region:347879-349384:1
so has part: feature:347879-349384:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:347879-349384:1:exon

YBR056W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MRX18
locus tag: YBR056W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005758 mitochondrial intermembrane space [PMID:22984289]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
note: Putative glycoside hydrolase of the mitochondrial intermembrane space
codon start: 1
product: 17-beta-hydroxysteroid dehydrogenase-like protein
translation: MIGSLRNKFEHFKVSEKGGQNLSTTLPKLPPAKDLDRSTIYKYRYNYGVNLGALFVLEPWIFSKETICTIDGKEYDSEFDAISQQLKKHSSEDVAKMLSDHYKKYIDRIDWEWLSKDAHITALRIPIGYWHVEDGKHLDSLPFAPLRKVYELAKPWEKLGELINNAKKMSIGVLIDLHGLPGGANCDSHSGSKSGEAAFFHKEKYMTKVYKDILPAIINTMTLGNENIIGIQVVNEACFDNNPKGQKFYYSEAINTVEKLQPGLPVIISDGWWPQQWADWVKEKHFSEIVVIDSHVYRCFSDSDKSKDANSIIKDLPNTVNFPHEDADYTVGEFSGVLDGQTWNKTSGDRDAIVQKYVQTQADVFSHVASWGWFFWTLQFEYGDGGEWGLAPMMQKGNLPKRPHGDDLQVDKKKIDSIIHEHEAYWNGKGKNFEHWRFEDGIKTAVDDIIAFRKFDNSLIGRWHSWKSQRRAEYVSAKKDSEFMWEWDQGYQRGLDEFNKY
SIO_010081: YBR056W
subclass of: SO_0000673
so part of: YBR056W
location: 347879..349384
location: region:347879-349384:1
so has part: feature:347879-349384:1:exon

NP_009612.1
type: Protein
SIO_000068: ncbiprotein

S000000260
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:347879-349384:1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 350459..350751
location: region:350459-350751:1
so has part: feature:350459-350751:1:region

S000006819
type: SGD
SIO_000068: sgd

position:350459:1
position: 350459
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:350751:1
position: 350751
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:350459-350751:1:region

YNCB0013W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCB0013W
so part of: sequence
location: 350827..350898
location: region:350827-350898:1
so has part: feature:350827-350898:1:exon
subclass of: SO_0000663

852347
type: Gene
SIO_000068: ncbigene

position:350827:1
position: 350827
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:350898:1
position: 350898
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:350827-350898:1:exon

YNCB0013W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCB0013W
product: tRNA-Gln
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Glutamine tRNA (tRNA-Gln), predicted by tRNAscan-SE analysis; thiolation of uridine at wobble position (34) requires Ncs6p
SIO_010081: YNCB0013W
subclass of: SO_0000673
so part of: YNCB0013W
location: 350827..350898
location: region:350827-350898:1
so has part: feature:350827-350898:1:exon

S000006691
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:350827-350898:1:exon

YBR056W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MNC1
locus tag: YBR056W-A
so part of: sequence
location: <351255..>351455
location: region:351255-351455:1
so has part: feature:351255-351455:1:exon
subclass of: SO_0000010

1466443
type: Gene
SIO_000068: ncbigene

position:351255:1
position: 351255
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:351455:1
position: 351455
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:351255-351455:1:exon

YBR056W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MNC1
locus tag: YBR056W-A
product: Mnc1p
transcript id: NM_001270739.1
SIO_010081: YBR056W-A
subclass of: SO_0000673
so part of: YBR056W-A
location: <351255..>351455
location: region:351255-351455:1
so has part: feature:351255-351455:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:351255-351455:1:exon

YBR056W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MNC1
locus tag: YBR056W-A
note: Putative membrane protein upregulated in toxic manganese levels; mRNA identified as translated by ribosome profiling data; partially overlaps dubious ORF YBR056C-B; YBR056W-A has a paralog, YDR034W-B, that arose from the whole genome duplication
codon start: 1
product: Mnc1p
translation: MRHQYYQPQPMYYQPQPQPIYIQQGPPPPRNDCCCCCNCGDCCSAIANVLCCLCLIDLCCSCAGGM
SIO_010081: YBR056W-A
subclass of: SO_0000673
so part of: YBR056W-A
location: 351255..351455
location: region:351255-351455:1
so has part: feature:351255-351455:1:exon

NP_001257668.1
type: Protein
SIO_000068: ncbiprotein

S000028736
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:351255-351455:1:exon

YBR057C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MUM2
locus tag: YBR057C
so part of: sequence
location: complement(<352193..>353293)
location: region:352193-353293:-1
so has part: feature:352193-353293:-1:exon
subclass of: SO_0000010

852348
type: Gene
SIO_000068: ncbigene

position:352193:-1
position: 352193
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:353293:-1
position: 353293
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:352193-353293:-1:exon

YBR057C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MUM2
locus tag: YBR057C
product: Mum2p
transcript id: NM_001178405.1
SIO_010081: YBR057C
subclass of: SO_0000673
so part of: YBR057C
location: complement(<352193..>353293)
location: region:352193-353293:-1
so has part: feature:352193-353293:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:352193-353293:-1:exon

YBR057C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MUM2
locus tag: YBR057C
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0036396 RNA N6-methyladenosine methyltransferase complex [PMID:22685417]
experiment: EXISTENCE:genetic interaction:GO:0080009 mRNA methylation [PMID:22685417]
experiment: EXISTENCE:mutant phenotype:GO:0006279 premeiotic DNA replication [PMID:9504908]
experiment: EXISTENCE:mutant phenotype:GO:0051321 meiotic cell cycle [PMID:22685417]
experiment: EXISTENCE:mutant phenotype:GO:0080009 mRNA methylation [PMID:22685417]
experiment: EXISTENCE:mutant phenotype:GO:2000221 negative regulation of pseudohyphal growth [PMID:22685417]
experiment: EXISTENCE:physical interaction:GO:0005515 protein binding [PMID:22685417]
experiment: EXISTENCE:physical interaction:GO:0036396 RNA N6-methyladenosine methyltransferase complex [PMID:22685417]
note: Protein essential for meiotic DNA replication and sporulation; cytoplasmic protein; subunit of the MIS complex which controls mRNA methylation during during the induction of sporulation; also interacts with Orc2p, which is a component of the origin recognition complex
codon start: 1
product: Mum2p
translation: MNYMAYDYDPQHSLETSFNNLAFHPHQQSQQQALYESGERNDARPGLMNTLGQASKMNNSMLPQGSSASPLTGQHSLNSTTNFNMPPSMNTYNYQNVPQASMRNTLNHNNIMNGATANDYWLDPMNNMTNNKDTNGNPNDSMSSMSNMTAKTSINSTAFKNSFVPFNHVTALSMNNVNSNEMNSNKDDRMEALEVELQIKESQIESLENEIQRLKKIFNEGLNYKQNEHKYEKENCHIPQTFELPASLEVIFRKLSSSLHAKEKELAETKENLESILTALALNPTNSVTKYGRYDAESIAHKMVVRLENLTNENKEMAKMLAYGRSKETQIELQLAKKENLELREKIASLEAHLASKESSKEDVAN
SIO_010081: YBR057C
subclass of: SO_0000673
so part of: YBR057C
location: complement(352193..353293)
location: region:352193-353293:-1
so has part: feature:352193-353293:-1:exon

NP_009613.1
type: Protein
SIO_000068: ncbiprotein

S000000261
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:352193-353293:-1:exon

YBR058C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: GID6
gene: UBP14
locus tag: YBR058C
gene synonym: GID6
so part of: sequence
location: complement(<353672..>356017)
location: region:353672-356017:-1
so has part: feature:353672-356017:-1:exon
subclass of: SO_0000010

852349
type: Gene
SIO_000068: ncbigene

position:353672:-1
position: 353672
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:356017:-1
position: 356017
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:353672-356017:-1:exon

YBR058C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: GID6
gene: UBP14
locus tag: YBR058C
gene synonym: GID6
product: ubiquitin-specific protease UBP14
transcript id: NM_001178406.1
SIO_010081: YBR058C
subclass of: SO_0000673
so part of: YBR058C
location: complement(<353672..>356017)
location: region:353672-356017:-1
so has part: feature:353672-356017:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:353672-356017:-1:exon

YBR058C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: GID6
gene: UBP14
locus tag: YBR058C
gene synonym: GID6
EC number: 3.4.19.12
experiment: EXISTENCE:curator inference:GO:0005737 cytoplasm [PMID:8982460]
experiment: EXISTENCE:direct assay:GO:0004843 cysteine-type deubiquitinase activity [PMID:19410548]
experiment: EXISTENCE:mutant phenotype:GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process [PMID:12686616]
experiment: EXISTENCE:mutant phenotype:GO:0045721 negative regulation of gluconeogenesis [PMID:12686616]
note: Ubiquitin-specific protease; specifically disassembles unanchored ubiquitin chains; involved in fructose-1,6-bisphosphatase (Fbp1p) degradation; similar to human isopeptidase T
codon start: 1
product: ubiquitin-specific protease UBP14
translation: MAEAVLENVNVPAVVSKDECIYCFESPYNEPLALNASPKHSLNICLNCFQATCNRHVPLHIRVTEYACDTIHSNYLTIAKVEKPKQENVEENNNNKKIKLQVIETSEDDTHNTIWSLQRFNGENVPRTVLSKSTDSDISSTALEKIEKILKAKSQDFEDKKNSWVLEISTCPHTENFQIPSKPENTVNLNQCSSCDLTQNLWLCLHCGNIGCGREQIGIDGHSHALDHYRSNNNHPLAIKLGSLSSSTYDLYCYACDDETRFPDNVNLGSALQIYGINIQEKIADEKTLVQLQVEQNENWQFRMVDSSGKEFEKLSASKNYGCGLINLGNSCYLNSVIQSLVNGGVPNWSLDFLGSKFPLDVVYPDNNLKCQWIKLLNAMKCEPELYPNGIKPTTFKKCIGQNHQEFSSNRQQDAMEFLTFLLDLLDKKFFSSSSSGIPNPNDLVRFMMEDRLQCNICGKVKYSYEPTEAIQIPLEENDEPQDMLERIKAYFEGQTIEFKCANCKEKVTANKKPGFKSLPQTLILNPIRIRLQNWIPVKTSNELSLPGLIDRDDMLDVSSYLSQGFDPQTENLLPDEDENRSSFTPNQCSISQLIEMGFTQNASVRALFNTGNQDAESAMNWLFQHMDDPDLNDPFVPPPNVPKKDKREVDEVSLTSMLSMGLNPNLCRKALILNNGDVNRSVEWVFNNMDDDGTFPEPEVPNEEQQQKKDLGYSTAKPYALTAVICHKGNSVHSGHYVVFIRKLVADKWKWVLYNDEKLVAADSIEDMKKNGYIYFYTRC
SIO_010081: YBR058C
subclass of: SO_0000673
so part of: YBR058C
location: complement(353672..356017)
location: region:353672-356017:-1
so has part: feature:353672-356017:-1:exon

NP_009614.2
type: Protein
SIO_000068: ncbiprotein

S000000262
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:353672-356017:-1:exon

YBR058C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TSC3
locus tag: YBR058C-A
so part of: sequence
location: complement(<356324..>356566)
location: region:356324-356566:-1
so has part: feature:356324-356566:-1:exon
subclass of: SO_0000010

852350
type: Gene
SIO_000068: ncbigene

position:356324:-1
position: 356324
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:356566:-1
position: 356566
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:356324-356566:-1:exon

YBR058C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TSC3
locus tag: YBR058C-A
product: Tsc3p
transcript id: NM_001184442.3
SIO_010081: YBR058C-A
subclass of: SO_0000673
so part of: YBR058C-A
location: complement(<356324..>356566)
location: region:356324-356566:-1
so has part: feature:356324-356566:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:356324-356566:-1:exon

YBR058C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TSC3
locus tag: YBR058C-A
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0008047 enzyme activator activity [PMID:10713067]
experiment: EXISTENCE:direct assay:GO:0035339 SPOTS complex [PMID:20182505]
experiment: EXISTENCE:mutant phenotype:GO:0008047 enzyme activator activity [PMID:10713067]
experiment: EXISTENCE:mutant phenotype:GO:0090154 positive regulation of sphingolipid biosynthetic process [PMID:10713067|PMID:23286903]
experiment: EXISTENCE:physical interaction:GO:0006666 3-keto-sphinganine metabolic process [PMID:10713067]
note: Protein that stimulates the activity of serine palmitoyltransferase; involved in sphingolipid biosynthesis; Lcb1p and Lcb2p are the two components of serine palmitoyltransferase
codon start: 1
product: Tsc3p
translation: MTQHKSSMVYIPTTKEAKRRNGKSEGILNTIEEVVEKLYWTYYIHLPFYLMASFDSFFLHVFFLTIFSLSFFGILKYCFL
SIO_010081: YBR058C-A
subclass of: SO_0000673
so part of: YBR058C-A
location: complement(356324..356566)
location: region:356324-356566:-1
so has part: feature:356324-356566:-1:exon

NP_116327.3
type: Protein
SIO_000068: ncbiprotein

S000007521
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:356324-356566:-1:exon

YBR059C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: AKL1
locus tag: YBR059C
so part of: sequence
location: complement(<356861..>360187)
location: region:356861-360187:-1
so has part: feature:356861-360187:-1:exon
subclass of: SO_0000010

852351
type: Gene
SIO_000068: ncbigene

position:356861:-1
position: 356861
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:360187:-1
position: 360187
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:356861-360187:-1:exon

YBR059C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: AKL1
locus tag: YBR059C
product: serine/threonine protein kinase AKL1
transcript id: NM_001178407.1
SIO_010081: YBR059C
subclass of: SO_0000673
so part of: YBR059C
location: complement(<356861..>360187)
location: region:356861-360187:-1
so has part: feature:356861-360187:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:356861-360187:-1:exon

YBR059C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: AKL1
locus tag: YBR059C
EC number: 2.7.11.1
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:16319894]
experiment: EXISTENCE:direct assay:GO:0004674 protein serine/threonine kinase activity [PMID:29895620|PMID:12956961]
experiment: EXISTENCE:direct assay:GO:0005628 prospore membrane [PMID:24390141]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:14562095|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0004674 protein serine/threonine kinase activity [PMID:29895620]
experiment: EXISTENCE:mutant phenotype:GO:1900186 negative regulation of clathrin-dependent endocytosis [PMID:29895620|PMID:28069741|PMID:17178891]
note: Ser/Thr protein kinase; phosphorylates Pan1p, Sla1p and Ent1p to negatively regulate endocytosis in response to membrane stress; regulates actin cytoskeleton organization and clathrin-dependent endocytosis; phosphorylated and inhibited by upstream kinase, Fpk1p; member, along with Ark1p and Prk1p, of the Ark kinase family
codon start: 1
product: serine/threonine protein kinase AKL1
translation: MSITNGTSRSVSAMGHPAVERYTPGHIVCVGTHKVEVVNYLAEGGFAQIYVVKFLEYLNEFDNTASVPLKIGDVACLKRVLVQDENGLNEMRNEVEVMKKLKGAPNIVQYFDSNASRRRDGVQGFEVLLLMELCPNKSLLDYMNQRLSTKLTEAEIVKIMYDVALSISQMHYLPVSLIHRDIKIENVLVDAKNNFKLADFGSTSTCFPIVTTHQDIALLTQNIYVHTTPQYRSPEMIDLYRCLPINEKSDIWALGVFLYKLLFFTTPFEMTGQFAILHSKYEFPVNKYSSKLINLIIIMLAENPNLRPNIYQVLYHLCEILNVEVPIEDKYAEGAYNFSKYTQFQNKLQNVQLQMYQLQQKKIMQNNKLSDSEENLLNDMFLSSFEISSKLPMNASDGHAAVSRIPSQNVGQELEEEKESQSDQRKSTLSEDKSSRTTSNANSSGTANNPQEINTIQSPGIEDKSIFENKTPGELYYPSVSELDTYLDKELVKQSSDPTISEQSPRLNTQSLPQRQKSTSSYSSGGRSMKSTSYGAATIGSDEALANEKTAGINKMKQHKSNNPFPKMNVAYHSTNELSNDASNFFLEEQQQGQRYQQAQNQTGTQGNTFPDESQYQSRVEQQQQQQDQPKGPANYSQRNFYTGRDRSNKPMQLGGTIAGDSGNRRVNFQNISQNYATNSQSGYLPSQNSPAIPMVRPVISMNQQQAQQIQAQQLQAQQMQAKQQMQAKQQMQVQQQLQVQQQMQIQNANNNGTYVSDRTNHTTEDMRNAQGGEPPILAGNSANEPMHSSSKNEALLIELSPLKEDAGKQSFQDTNEPQTGGIEDAGGSGTIKGSNNNRNGVLNLSLNEMDLSRDDTGAAVSSFSSSSSSASIQQAKLSGRKGSSKRNNYSTDELGDSMVSSESIDIDLDDARRGKTAERRPLHNERGHKDQARSSDASKSNQFKSKDFSSVSTRQPRQSLDLNFQEVNLSSPTLTQEHRNKNDSPAPNSHHSYRVSPHASTAITENKRHSTGHELSTRSNGKHETHRTGSKQRHDLERYRHSKDKDSNSSITISTSTPSEMRKSFARARQSLDLERVRREAMASSASSSGGSNGKRRSFFSVFRSEK
SIO_010081: YBR059C
subclass of: SO_0000673
so part of: YBR059C
location: complement(356861..360187)
location: region:356861-360187:-1
so has part: feature:356861-360187:-1:exon

NP_009615.1
type: Protein
SIO_000068: ncbiprotein

S000000263
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:356861-360187:-1:exon

YBR060C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RRR1
alternative label: SIR5
gene: ORC2
locus tag: YBR060C
gene synonym: RRR1; SIR5
so part of: sequence
location: complement(<360652..>362514)
location: region:360652-362514:-1
so has part: feature:360652-362514:-1:exon
subclass of: SO_0000010

852352
type: Gene
SIO_000068: ncbigene

position:360652:-1
position: 360652
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:362514:-1
position: 362514
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:360652-362514:-1:exon

YBR060C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RRR1
alternative label: SIR5
gene: ORC2
locus tag: YBR060C
gene synonym: RRR1; SIR5
product: origin recognition complex subunit 2
transcript id: NM_001178408.1
SIO_010081: YBR060C
subclass of: SO_0000673
so part of: YBR060C
location: complement(<360652..>362514)
location: region:360652-362514:-1
so has part: feature:360652-362514:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:360652-362514:-1:exon

YBR060C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RRR1
alternative label: SIR5
gene: ORC2
locus tag: YBR060C
gene synonym: RRR1; SIR5
experiment: EXISTENCE:direct assay:GO:0003682 chromatin binding [PMID:9159120|PMID:9288745]
experiment: EXISTENCE:direct assay:GO:0003688 DNA replication origin binding [PMID:16824194|PMID:9288745]
experiment: EXISTENCE:direct assay:GO:0005656 nuclear pre-replicative complex [PMID:16824194|PMID:9335335]
experiment: EXISTENCE:direct assay:GO:0005664 nuclear origin of replication recognition complex [PMID:9372948]
experiment: EXISTENCE:direct assay:GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication [PMID:16824194]
experiment: EXISTENCE:direct assay:GO:0030466 silent mating-type cassette heterochromatin formation [PMID:12897051]
experiment: EXISTENCE:direct assay:GO:0031261 DNA replication preinitiation complex [PMID:9554851]
experiment: EXISTENCE:genetic interaction:GO:0006270 DNA replication initiation [PMID:7579692]
experiment: EXISTENCE:mutant phenotype:GO:0005664 nuclear origin of replication recognition complex [PMID:9372948]
experiment: EXISTENCE:mutant phenotype:GO:0006270 DNA replication initiation [PMID:16716188|PMID:7579692]
experiment: EXISTENCE:mutant phenotype:GO:0031509 subtelomeric heterochromatin formation [PMID:16980387]
note: Subunit of the origin recognition complex (ORC); ORC directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; interacts with Spp1p and with trimethylated histone H3; phosphorylated by Cdc28p
codon start: 1
product: origin recognition complex subunit 2
translation: MLNGEDFVEHNDILSSPAKSRNVTPKRVDPHGERQLRRIHSSKKNLLERISLVGNERKNTSPDPALKPKTPSKAPRKRGRPRKIQEELTDRIKKDEKDTISSKKKRKLDKDTSGNVNEESKTSNNKQVMEKTGIKEKREREKIQVATTTYEDNVTPQTDDNFVSNSPEPPEPATPSKKSLTTNHDFTSPLKQIIMNNLKEYKDSTSPGKLTLSRNFTPTPVPKNKKLYQTSETKSASSFLDTFEGYFDQRKIVRTNAKSRHTMSMAPDVTREEFSLVSNFFNENFQKRPRQKLFEIQKKMFPQYWFELTQGFSLLFYGVGSKRNFLEEFAIDYLSPKIAYSQLAYENELQQNKPVNSIPCLILNGYNPSCNYRDVFKEITDLLVPAELTRSETKYWGNHVILQIQKMIDFYKNQPLDIKLILVVHNLDGPSIRKNTFQTMLSFLSVIRQIAIVASTDHIYAPLLWDNMKAQNYNFVFHDISNFEPSTVESTFQDVMKMGKSDTSSGAEGAKYVLQSLTVNSKKMYKLLIETQMQNMGNLSANTGPKRGTQRTGVELKLFNHLCAADFIASNEIALRSMLREFIEHKMANITKNNSGMEIIWVPYTYAELEKLLKTVLNTL
SIO_010081: YBR060C
subclass of: SO_0000673
so part of: YBR060C
location: complement(360652..362514)
location: region:360652-362514:-1
so has part: feature:360652-362514:-1:exon

NP_009616.1
type: Protein
SIO_000068: ncbiprotein

S000000264
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:360652-362514:-1:exon

YBR061C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TRM7
locus tag: YBR061C
so part of: sequence
location: complement(<364787..>365719)
location: region:364787-365719:-1
so has part: feature:364787-365719:-1:exon
subclass of: SO_0000010

852353
type: Gene
SIO_000068: ncbigene

position:364787:-1
position: 364787
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:365719:-1
position: 365719
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:364787-365719:-1:exon

YBR061C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TRM7
locus tag: YBR061C
product: tRNA methyltransferase TRM7
transcript id: NM_001178409.3
SIO_010081: YBR061C
subclass of: SO_0000673
so part of: YBR061C
location: complement(<364787..>365719)
location: region:364787-365719:-1
so has part: feature:364787-365719:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:364787-365719:-1:exon

YBR061C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TRM7
locus tag: YBR061C
EC number: 2.1.1.205
experiment: EXISTENCE:direct assay:GO:0002128 tRNA nucleoside ribose methylation [PMID:11927565]
experiment: EXISTENCE:direct assay:GO:0002130 wobble position ribose methylation [PMID:11927565]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11927565]
experiment: EXISTENCE:direct assay:GO:0106050 tRNA 2'-O-methyltransferase activity [PMID:11927565]
experiment: EXISTENCE:mutant phenotype:GO:0002130 wobble position ribose methylation [PMID:22912484]
experiment: EXISTENCE:mutant phenotype:GO:0002181 cytoplasmic translation [PMID:11927565]
note: 2'-O-ribose methyltransferase; methylates the 2'-O-ribose of tRNA-Phe, tRNA-Trp, and tRNA-Leu at positions C32 and N34 of tRNA anticodon loop; crucial biological role likely modification of tRNA-Phe; interacts with Trm732p and Rtt10p in 2'-O-methylation of C32 and N34 substrate tRNAs, respectively; yeast null mutant can be functionally complemented by human FTSJ1, mutations in which have been implicated in nonsyndromic X-linked intellectual disability (NSXLID)
codon start: 1
product: tRNA methyltransferase TRM7
translation: MGKSSKDKRDLYYRKAKEQGYRARSAFKLLQLNDQFHFLDDPNLKRVVDLCAAPGSWSQVLSRKLFDESPSSDKEDRKIVSVDLQPMSPIPHVTTLQADITHPKTLARILKLFGNEKADFVCSDGAPDVTGLHDLDEYVQQQLIMSALQLTACILKKGGTFVAKIFRGRDIDMLYSQLGYLFDKIVCAKPRSSRGTSLEAFIVCLGYNPPSNWTPKLDVNTSVDEFFQGCFLNKLCISDKLSHWNEEERNIAEFMACGSLQSFDSDATYHDLPSSVAGTSSSLDPVQSPTNPPYKKALELKRSGKLTRSV
SIO_010081: YBR061C
subclass of: SO_0000673
so part of: YBR061C
location: complement(364787..365719)
location: region:364787-365719:-1
so has part: feature:364787-365719:-1:exon

NP_009617.3
type: Protein
SIO_000068: ncbiprotein

S000000265
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:364787-365719:-1:exon

YBR062C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBR062C
so part of: sequence
location: complement(<365976..>366600)
location: region:365976-366600:-1
so has part: feature:365976-366600:-1:exon
subclass of: SO_0000010

852354
type: Gene
SIO_000068: ncbigene

position:365976:-1
position: 365976
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:366600:-1
position: 366600
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:365976-366600:-1:exon

YBR062C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBR062C
product: uncharacterized protein
transcript id: NM_001178410.1
SIO_010081: YBR062C
subclass of: SO_0000673
so part of: YBR062C
location: complement(join(<365976..366502,366585..>366600))
location: region:365976-366600:-1
so has part: feature:366585-366600:-1:exon
so has part: feature:365976-366502:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:366585-366600:-1:exon

position:366585:-1
position: 366585
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:365976-366502:-1:exon

position:366502:-1
position: 366502
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YBR062C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBR062C
note: hypothetical protein that interacts with Msb2p; may play a role in activation of the filamentous growth pathway
codon start: 1
product: uncharacterized protein
translation: MSTYEEEHGIQQNSRDYQEVGGTSQEEQRRQVRSQLQGLFQNFGNTSGEGDAHSDSTLLLRLLSQMLPESLQEEWLQEMDKGKSAGCPDTFAASLPRINKKKLKATDNCSICYTNYLEDEYPLVVELPHCHHKFDLECLSVWLSRSTTCPLCRDNVMGHRIINEIDTTEAELEEDWGMYG
SIO_010081: YBR062C
subclass of: SO_0000673
so part of: YBR062C
location: complement(join(365976..366502,366585..366600))
location: region:365976-366600:-1
so has part: feature:366585-366600:-1:exon
so has part: feature:365976-366502:-1:exon

NP_009618.2
type: Protein
SIO_000068: ncbiprotein

S000000266
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:366585-366600:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:365976-366502:-1:exon

YBR063C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CNM1
locus tag: YBR063C
so part of: sequence
location: complement(<366970..>368184)
location: region:366970-368184:-1
so has part: feature:366970-368184:-1:exon
subclass of: SO_0000010

852356
type: Gene
SIO_000068: ncbigene

position:366970:-1
position: 366970
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:368184:-1
position: 368184
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:366970-368184:-1:exon

YBR063C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CNM1
locus tag: YBR063C
product: Cnm1p
transcript id: NM_001178411.1
SIO_010081: YBR063C
subclass of: SO_0000673
so part of: YBR063C
location: complement(<366970..>368184)
location: region:366970-368184:-1
so has part: feature:366970-368184:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:366970-368184:-1:exon

YBR063C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CNM1
locus tag: YBR063C
experiment: EXISTENCE:direct assay:GO:0005515 protein binding [PMID:34694322]
experiment: EXISTENCE:direct assay:GO:0005635 nuclear envelope [PMID:34694322]
experiment: EXISTENCE:direct assay:GO:0005741 mitochondrial outer membrane [PMID:34694322]
experiment: EXISTENCE:direct assay:GO:0044232 organelle membrane contact site [PMID:34694322]
experiment: EXISTENCE:direct assay:GO:0140056 organelle localization by membrane tethering [PMID:34694322]
note: Molecular tether on nuclear membrane; mediates contact by interacting with Tom70p on mitochondria; protein abundance is regulated by phosphatidylcholine, enabling coupling of phospholipid homeostasis with contact extent
codon start: 1
product: Cnm1p
translation: MEELGLKSTFPYEYGSDFTMIRTEMLNTTKSETTILFSNIKSILAIIWKYSFTFLRSFSDSIKLIIDDVVTIGSRNFAERLQIEAKKNNDQEDIWASTIILGVIIGYLISSIKRKNTFPIMPTSSPKIDDCRFKTGDTISIVINFNEDCLNNRSDVTEERNYEESTVLHSKESVLSIGRQNMVTLNQSDENFTYGNFDEYDLLTKDYTTEVLTRSPGSNPEFKAVVNNTLLDSANETPFKGIEKSINETMVKVPMGCDVSLSHYGRQYAPGNISIMRSFTARDNTKSVSREIRDICKSFLIIKSQFGDELFLTMFMEKPVFFDNNIPIEITGAYREKRERLDEVIHKDLIRYDEVQNLTRIRNLLRVKSQKICSRRHNSSVPTKKLLVNDKGATSILLWYSNYS
SIO_010081: YBR063C
subclass of: SO_0000673
so part of: YBR063C
location: complement(366970..368184)
location: region:366970-368184:-1
so has part: feature:366970-368184:-1:exon

NP_009619.1
type: Protein
SIO_000068: ncbiprotein

S000000267
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:366970-368184:-1:exon

YBR065C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SLT11
gene: ECM2
locus tag: YBR065C
gene synonym: SLT11
so part of: sequence
location: complement(<368584..>369678)
location: region:368584-369678:-1
so has part: feature:368584-369678:-1:exon
subclass of: SO_0000010

852357
type: Gene
SIO_000068: ncbigene

position:368584:-1
position: 368584
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:369678:-1
position: 369678
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:368584-369678:-1:exon

YBR065C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SLT11
gene: ECM2
locus tag: YBR065C
gene synonym: SLT11
product: Ecm2p
transcript id: NM_001178413.3
SIO_010081: YBR065C
subclass of: SO_0000673
so part of: YBR065C
location: complement(<368584..>369678)
location: region:368584-369678:-1
so has part: feature:368584-369678:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:368584-369678:-1:exon

YBR065C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SLT11
gene: ECM2
locus tag: YBR065C
gene synonym: SLT11
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0017070 U6 snRNA binding [PMID:33547186]
experiment: EXISTENCE:genetic interaction:GO:0000398 mRNA splicing, via spliceosome [PMID:9528778]
note: Pre-mRNA splicing factor; facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome, function may be regulated by Slu7p
codon start: 1
product: Ecm2p
translation: MNDEINEPPPNICEQCLGDEANIRMTKIPQGSECKICTLPFTLYHFKTSKRSNNIIKTLICVRCATQRNICQCCMLDSRWHIPIQLRDHLISLVNEENVMTEEAKNDMMKRFLSLKNVKLGGAQITSDPSEADNIVDKLKNILLRATSDGPSTPLIKNTTALYKNEKGANEVKNLEKYASVDISHILKKLPLNESFLKNPSTKSFFLYNIDASIPEWKITDTVSQLLGIKKWKDGNSLSLIVNHKAKCGGLRFQSSELGERFVSKISETLVTPKGLKRGVLLIDRFRIFIIPWSSGFSAASFGTNTAENIKLSLSLNKLIQLELGLSFPTKSTDNAKNDKKKTSKKVHKDRSKKSKPRANKLTI
SIO_010081: YBR065C
subclass of: SO_0000673
so part of: YBR065C
location: complement(368584..369678)
location: region:368584-369678:-1
so has part: feature:368584-369678:-1:exon

NP_009621.3
type: Protein
SIO_000068: ncbiprotein

S000000269
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:368584-369678:-1:exon

YBR066C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: NRG2
locus tag: YBR066C
so part of: sequence
location: complement(<370037..>370699)
location: region:370037-370699:-1
so has part: feature:370037-370699:-1:exon
subclass of: SO_0000010

852358
type: Gene
SIO_000068: ncbigene

position:370037:-1
position: 370037
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:370699:-1
position: 370699
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:370037-370699:-1:exon

YBR066C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: NRG2
locus tag: YBR066C
product: Nrg2p
transcript id: NM_001178414.1
SIO_010081: YBR066C
subclass of: SO_0000673
so part of: YBR066C
location: complement(<370037..>370699)
location: region:370037-370699:-1
so has part: feature:370037-370699:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:370037-370699:-1:exon

YBR066C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: NRG2
locus tag: YBR066C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:20802496]
experiment: EXISTENCE:genetic interaction:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:12024013|PMID:15466424|PMID:16278455]
experiment: EXISTENCE:genetic interaction:GO:0000433 carbon catabolite repression of transcription from RNA polymerase II promoter by glucose [PMID:16278455]
experiment: EXISTENCE:genetic interaction:GO:0043709 cell adhesion involved in single-species biofilm formation [PMID:12024013]
experiment: EXISTENCE:genetic interaction:GO:2000221 negative regulation of pseudohyphal growth [PMID:12024013]
experiment: EXISTENCE:mutant phenotype:GO:0000433 carbon catabolite repression of transcription from RNA polymerase II promoter by glucose [PMID:11404322]
note: Transcriptional repressor; mediates glucose repression and negatively regulates filamentous growth; activated in stochastic pulses of nuclear localization in response to low glucose
codon start: 1
product: Nrg2p
translation: MSIGYKDNLMSTILAKDRKCEFPINFECSPSQITLMPEMFSFNNERKYQTLIPLMKTSHLIDDDLKDKLNKCAFDFFSGKQANRTSDGTISRLTASGKTSPILPLQNINIVKAENTGNGKSDPYSSIKISKPTKTVIKLKSTKTNTAGQRTRHFCKICSTGFTTSGHLSRHNRIHTGEKNHICPHEGCGQRFSRHDNCNQHYRTHANKKKRNWKRREASS
SIO_010081: YBR066C
subclass of: SO_0000673
so part of: YBR066C
location: complement(370037..370699)
location: region:370037-370699:-1
so has part: feature:370037-370699:-1:exon

NP_009622.1
type: Protein
SIO_000068: ncbiprotein

S000000270
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:370037-370699:-1:exon

YBR067C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TIP1
locus tag: YBR067C
so part of: sequence
location: complement(<372103..>372735)
location: region:372103-372735:-1
so has part: feature:372103-372735:-1:exon
subclass of: SO_0000010

852359
type: Gene
SIO_000068: ncbigene

position:372103:-1
position: 372103
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:372735:-1
position: 372735
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:372103-372735:-1:exon

YBR067C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TIP1
locus tag: YBR067C
product: putative lipase
transcript id: NM_001178415.1
SIO_010081: YBR067C
subclass of: SO_0000673
so part of: YBR067C
location: complement(<372103..>372735)
location: region:372103-372735:-1
so has part: feature:372103-372735:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:372103-372735:-1:exon

YBR067C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TIP1
locus tag: YBR067C
experiment: EXISTENCE:direct assay:GO:0005199 structural constituent of cell wall [PMID:10216230]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0009277 fungal-type cell wall [PMID:10216230|PMID:15781460]
experiment: EXISTENCE:direct assay:GO:0016298 lipase activity [PMID:9818717]
experiment: EXISTENCE:direct assay:GO:0031505 fungal-type cell wall organization [PMID:10216230]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
note: Major cell wall mannoprotein with possible lipase activity; transcription is induced by heat- and cold-shock; member of the Srp1p/Tip1p family of serine-alanine-rich proteins
codon start: 1
product: putative lipase
translation: MSVSKIAFVLSAIASLAVADTSAAETAELQAIIGDINSHLSDYLGLETGNSGFQIPSDVLSVYQQVMTYTDDAYTTLFSELDFDAITKTIVKLPWYTTRLSSEIAAALASVSPASSEAASSSEAASSSKAASSSEATSSAAPSSSAAPSSSAAPSSSAESSSKAVSSSVAPTTSSVSTSTVETASNAGQRVNAGAASFGAVVAGAAALLL
SIO_010081: YBR067C
subclass of: SO_0000673
so part of: YBR067C
location: complement(372103..372735)
location: region:372103-372735:-1
so has part: feature:372103-372735:-1:exon

NP_009623.1
type: Protein
SIO_000068: ncbiprotein

S000000271
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:372103-372735:-1:exon

YBR068C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: BAP2
locus tag: YBR068C
so part of: sequence
location: complement(<373861..>375690)
location: region:373861-375690:-1
so has part: feature:373861-375690:-1:exon
subclass of: SO_0000010

852360
type: Gene
SIO_000068: ncbigene

position:373861:-1
position: 373861
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:375690:-1
position: 375690
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:373861-375690:-1:exon

YBR068C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: BAP2
locus tag: YBR068C
product: branched-chain amino acid permease BAP2
transcript id: NM_001178416.4
SIO_010081: YBR068C
subclass of: SO_0000673
so part of: YBR068C
location: complement(<373861..>375690)
location: region:373861-375690:-1
so has part: feature:373861-375690:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:373861-375690:-1:exon

YBR068C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: BAP2
locus tag: YBR068C
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:10654085]
experiment: EXISTENCE:direct assay:GO:0006865 amino acid transport [PMID:10654085]
experiment: EXISTENCE:direct assay:GO:0015171 amino acid transmembrane transporter activity [PMID:10654085]
experiment: EXISTENCE:direct assay:GO:0055085 transmembrane transport [PMID:10654085]
note: High-affinity leucine permease; functions as a branched-chain amino acid permease involved in uptake of leucine, isoleucine and valine; contains 12 predicted transmembrane domains; BAP2 has a paralog, BAP3, that arose from the whole genome duplication
codon start: 1
product: branched-chain amino acid permease BAP2
translation: MLSSEDFGSSGKKETSPDSISIRSFSAGNNFQSSSSEKTYSKQKSGSDKLIHRFADSFKRAEGSTTRTKQINENTSDLEDGVESITSDSKLKKSMKSRHVVMMSLGTGIGTGLLVANAKGLHYGGPAALIIGYILVSFVTYFMIQAAGEMAVTYPTLPANFNAYSSIFISKSFGFATVWLYCFQWLTVLPLELITASMTIQFWNDKINPDIYILIFYVFLVFIHFFGVKAYGETEFIFNCCKILMIAGFIILSIVINCGGAGNDGYIGATYWHNPGAFAGDTSIGRFKNVCYILVTAYFSFGGMELFALSVQEQSNPRKSTPVAAKRSIYRIVVIYLLTMILIGFNVPYNDDQLMGAGGSATHASPYVLAASIHGVKIVPHIINAVILISVVSVANSSLYAGPRLICSLAQQGYAPKFLDYVDREGRPLRALIVCCVFGVIAFVAASSKEEIVFTWLAAIAGLSELFTWTSIMLSHLRFRQAMKVQGRSLDELGYKATTGIWGSIYGVFFNILVFVAQFWVALAPLGNGGKCDAESFFQNYLAFPIWLAFYFGYMVYNRDFTLLNPLDKIDLDFHRRIYDPELMRQEDEENKEKLRNMSLMRKAYHFWC
SIO_010081: YBR068C
subclass of: SO_0000673
so part of: YBR068C
location: complement(373861..375690)
location: region:373861-375690:-1
so has part: feature:373861-375690:-1:exon

NP_009624.4
type: Protein
SIO_000068: ncbiprotein

S000000272
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:373861-375690:-1:exon

YBR069C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: TAP1
alternative label: VAP1
gene: TAT1
locus tag: YBR069C
gene synonym: TAP1; VAP1
so part of: sequence
location: complement(<376574..>378433)
location: region:376574-378433:-1
so has part: feature:376574-378433:-1:exon
subclass of: SO_0000010

852361
type: Gene
SIO_000068: ncbigene

position:376574:-1
position: 376574
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:378433:-1
position: 378433
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:376574-378433:-1:exon

YBR069C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: TAP1
alternative label: VAP1
gene: TAT1
locus tag: YBR069C
gene synonym: TAP1; VAP1
product: amino acid transporter TAT1
transcript id: NM_001178417.1
SIO_010081: YBR069C
subclass of: SO_0000673
so part of: YBR069C
location: complement(<376574..>378433)
location: region:376574-378433:-1
so has part: feature:376574-378433:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:376574-378433:-1:exon

YBR069C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: TAP1
alternative label: VAP1
gene: TAT1
locus tag: YBR069C
gene synonym: TAP1; VAP1
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:23666621]
experiment: EXISTENCE:direct assay:GO:0006865 amino acid transport [PMID:10654085]
experiment: EXISTENCE:direct assay:GO:0015171 amino acid transmembrane transporter activity [PMID:10654085]
experiment: EXISTENCE:direct assay:GO:0055085 transmembrane transport [PMID:10654085]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0015827 tryptophan transport [PMID:7523855]
experiment: EXISTENCE:genetic interaction:GO:0022893 low-affinity tryptophan transmembrane transporter activity [PMID:7523855]
experiment: EXISTENCE:mutant phenotype:GO:0015828 tyrosine transport [PMID:7523855]
note: Amino acid transporter for valine, leucine, isoleucine, and tyrosine; low-affinity tryptophan and histidine transporter; overexpression confers FK506 and FTY720 resistance; protein abundance increases in response to DNA replication stress
codon start: 1
product: amino acid transporter TAT1
translation: MDDSVSFIAKEASPAQYSHSLHERTHSEKQKRDFTITEKQDEVSGQTAEPRRTDSKSILQRKCKEFFDSFKRQLPPDRNSELESQEKNNLTKSIKSRHLVMISLGTGIGTGLLVGNGQVLGTAGPAGLVLGYGIASIMLYCIIQAAGELGLCYAGLTGNYTRYPSILVDPSLGFAVSVVYTIQWLTVLPLQLVTAAMTVKYWTSVNADIFVAVVFVFVIIINLFGSRGYAEAEFIFNSCKILMVIGFVILAIIINCGGAGDRRYIGAEYWHNPGPFAHGFKGVCTVFCYAAFSYGGIEVLLLSAAEQENPTKSIPNACKKVVYRILLIYMLTTILVCFLVPYNSDELLGSSDSSGSHASPFVIAVASHGVKVVPHFINAVILISVISVANSSLYSGPRLLLSLAEQGVLPKCLAYVDRNGRPLLCFFVSLVFGCIGFVATSDAEEQVFTWLLAISSLSQLFIWMSMSLSHIRFRDAMAKQGRSMNEVGYKAQTGYWGSWLAVLIAIFFLVCQFWVAIAPVNEHGKLNVKVFFQNYLAMPIVLFAYFGHKIYFKSWSFWIPAEKIDLDSHRNIFVSPSLTEIDKVDDNDDLKEYENSESSENPNSSRSRKFFKRMTNFWC
SIO_010081: YBR069C
subclass of: SO_0000673
so part of: YBR069C
location: complement(376574..378433)
location: region:376574-378433:-1
so has part: feature:376574-378433:-1:exon

NP_009625.1
type: Protein
SIO_000068: ncbiprotein

S000000273
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:376574-378433:-1:exon

YNCB0014W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TBRT
locus tag: YNCB0014W
so part of: sequence
location: 376610..378633
location: region:376610-378633:1
so has part: feature:376610-378633:1:exon
subclass of: SO_0000011

65052915
type: Gene
SIO_000068: ncbigene

position:376610:1
position: 376610
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:378633:1
position: 378633
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:376610-378633:1:exon

YNCB0014W
type: Non Coding RNA
subclass of: SO_0000655
RO_0002162: 559292
nc RNA class: antisense_RNA
gene: TBRT
locus tag: YNCB0014W
product: TBRT
note: Antisense lncRNA XUT_2F-154 (TBRT); transcription mediates repression of BAP2 and TAT1
transcript id: NR_172475.1
SIO_010081: YNCB0014W
subclass of: SO_0000673
so part of: YNCB0014W
location: 376610..378633
location: region:376610-378633:1
so has part: feature:376610-378633:1:exon

S000303803
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:376610-378633:1:exon

YBR070C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ALG14
locus tag: YBR070C
so part of: sequence
location: complement(<379221..>379934)
location: region:379221-379934:-1
so has part: feature:379221-379934:-1:exon
subclass of: SO_0000010

852362
type: Gene
SIO_000068: ncbigene

position:379221:-1
position: 379221
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:379934:-1
position: 379934
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:379221-379934:-1:exon

YBR070C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ALG14
locus tag: YBR070C
product: N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase anchoring subunit ALG14
transcript id: NM_001178418.1
SIO_010081: YBR070C
subclass of: SO_0000673
so part of: YBR070C
location: complement(<379221..>379934)
location: region:379221-379934:-1
so has part: feature:379221-379934:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:379221-379934:-1:exon

YBR070C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ALG14
locus tag: YBR070C
experiment: EXISTENCE:direct assay:GO:0004577 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity [PMID:16100113]
experiment: EXISTENCE:direct assay:GO:0005777 peroxisome [PMID:35563734]
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:16100110|PMID:17686769]
experiment: EXISTENCE:direct assay:GO:0006488 dolichol-linked oligosaccharide biosynthetic process [PMID:16100113]
experiment: EXISTENCE:direct assay:GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network [PMID:15282802]
experiment: EXISTENCE:mutant phenotype:GO:0004577 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity [PMID:15615718|PMID:16100113]
experiment: EXISTENCE:mutant phenotype:GO:0006488 dolichol-linked oligosaccharide biosynthetic process [PMID:15615718|PMID:16100113]
experiment: EXISTENCE:mutant phenotype:GO:0043495 protein-membrane adaptor activity [PMID:16100110|PMID:16100113]
experiment: EXISTENCE:physical interaction:GO:0006488 dolichol-linked oligosaccharide biosynthetic process [PMID:16100110]
experiment: EXISTENCE:physical interaction:GO:0043541 UDP-N-acetylglucosamine transferase complex [PMID:16100110|PMID:16100113]
note: Component of UDP-GlcNAc transferase; required for second step of dolichyl-linked oligosaccharide synthesis; anchors catalytic subunit Alg13p to ER membrane; localizes to the peroxisome; similar to bacterial and human glycosyltransferases; both human homologs ALG13 and ALG14 are required to complement yeast alg14 mutant; mutations of human ALG14 cause congenital myasthenic syndrome
codon start: 1
product: N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase anchoring subunit ALG14
translation: MKTAYLASLVLIVSTAYVIRLIAILPFFHTQAGTEKDTKDGVNLLKIRKSSKKPLKIFVFLGSGGHTGEMIRLLENYQDLLLGKSIVYLGYSDEASRQRFAHFIKKFGHCKVKYYEFMKAREVKATLLQSVKTIIGTLVQSFVHVVRIRFAMCGSPHLFLLNGPGTCCIISFWLKIMELLLPLLGSSHIVYVESLARINTPSLTGKILYWVVDEFIVQWQELRDNYLPRSKWFGILV
SIO_010081: YBR070C
subclass of: SO_0000673
so part of: YBR070C
location: complement(379221..379934)
location: region:379221-379934:-1
so has part: feature:379221-379934:-1:exon

NP_009626.1
type: Protein
SIO_000068: ncbiprotein

S000000274
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:379221-379934:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS212; Autonomously Replicating Sequence
so part of: sequence
location: 379221..379912
location: region:379221-379912:1
so has part: feature:379221-379912:1:region

S000130151
type: SGD
SIO_000068: sgd

position:379221:1
position: 379221
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:379912:1
position: 379912
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:379221-379912:1:region

YBR071W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBR071W
so part of: sequence
location: <380411..>381046
location: region:380411-381046:1
so has part: feature:380411-381046:1:exon
subclass of: SO_0000010

852363
type: Gene
SIO_000068: ncbigene

position:380411:1
position: 380411
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:381046:1
position: 381046
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:380411-381046:1:exon

YBR071W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBR071W
product: uncharacterized protein
transcript id: NM_001178419.3
SIO_010081: YBR071W
subclass of: SO_0000673
so part of: YBR071W
location: <380411..>381046
location: region:380411-381046:1
so has part: feature:380411-381046:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:380411-381046:1:exon

YBR071W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBR071W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:21777356|PMID:11914276|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:21777356]
note: hypothetical protein found in the cytoplasm and bud neck; mRNA expression may be regulated by the cell cycle and/or cell wall stress; overexpression of YBR071W affects endocytic protein trafficking
codon start: 1
product: uncharacterized protein
translation: MLRRSKNSSTNTNADTKKRQSMHLGSKSSLISLTSEFGHGHSKTKQKKEEGTAPSQFLSPTNKRSTSSQSKLKRSSLLLDETLLKDYHSAMRHMQTNAAKEEKLRMAPSPTQSTRSESDASLSSTKSSISSIFSQDNDYSIHDLLYEDIEEMDKTDAFKINNTIAIDDSKALFVFCSNDSSSRTASIETLHESNLDNLDMGSSRRTSLDFF
SIO_010081: YBR071W
subclass of: SO_0000673
so part of: YBR071W
location: 380411..381046
location: region:380411-381046:1
so has part: feature:380411-381046:1:exon

NP_009627.3
type: Protein
SIO_000068: ncbiprotein

S000000275
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:380411-381046:1:exon

YBR072W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HSP26
locus tag: YBR072W
so part of: sequence
location: <382030..>382674
location: region:382030-382674:1
so has part: feature:382030-382674:1:exon
subclass of: SO_0000010

852364
type: Gene
SIO_000068: ncbigene

position:382030:1
position: 382030
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:382674:1
position: 382674
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:382030-382674:1:exon

YBR072W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HSP26
locus tag: YBR072W
product: chaperone protein HSP26
transcript id: NM_001178420.1
SIO_010081: YBR072W
subclass of: SO_0000673
so part of: YBR072W
location: <382030..>382674
location: region:382030-382674:1
so has part: feature:382030-382674:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:382030-382674:1:exon

YBR072W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: HSP26
locus tag: YBR072W
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:20844764]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:2645298]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:2645298|PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0006457 protein folding [PMID:10581247]
experiment: EXISTENCE:direct assay:GO:0010494 cytoplasmic stress granule [PMID:26777405|PMID:24291094]
experiment: EXISTENCE:direct assay:GO:0034605 cellular response to heat [PMID:10581247]
experiment: EXISTENCE:direct assay:GO:0051082 unfolded protein binding [PMID:10581247]
note: Small heat shock protein (sHSP) with chaperone activity; forms hollow, sphere-shaped oligomers that suppress unfolded proteins aggregation; long-lived protein that is preferentially retained in mother cells and forms cytoplasmic foci; oligomer activation requires heat-induced conformational change; also has mRNA binding activity
codon start: 1
product: chaperone protein HSP26
translation: MSFNSPFFDFFDNINNEVDAFNRLLGEGGLRGYAPRRQLANTPAKDSTGKEVARPNNYAGALYDPRDETLDDWFDNDLSLFPSGFGFPRSVAVPVDILDHDNNYELKVVVPGVKSKKDIDIEYHQNKNQILVSGEIPSTLNEESKDKVKVKESSSGKFKRVITLPDYPGVDADNIKADYANGVLTLTVPKLKPQKDGKNHVKKIEVSSQESWGN
SIO_010081: YBR072W
subclass of: SO_0000673
so part of: YBR072W
location: 382030..382674
location: region:382030-382674:1
so has part: feature:382030-382674:1:exon

NP_009628.1
type: Protein
SIO_000068: ncbiprotein

S000000276
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:382030-382674:1:exon

YBR072C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBR072C-A
so part of: sequence
location: complement(<382860..>383021)
location: region:382860-383021:-1
so has part: feature:382860-383021:-1:exon
subclass of: SO_0000010

1466444
type: Gene
SIO_000068: ncbigene

position:382860:-1
position: 382860
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:383021:-1
position: 383021
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:382860-383021:-1:exon

YBR072C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBR072C-A
product: uncharacterized protein
transcript id: NM_001184540.1
SIO_010081: YBR072C-A
subclass of: SO_0000673
so part of: YBR072C-A
location: complement(<382860..>383021)
location: region:382860-383021:-1
so has part: feature:382860-383021:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:382860-383021:-1:exon

YBR072C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBR072C-A
experiment: EXISTENCE:direct assay:GO:0005777 peroxisome [PMID:36164978]
note: hypothetical protein; identified by fungal homology and RT-PCR; localizes to cytosol and peroxisomes
codon start: 1
product: uncharacterized protein
translation: MHILTRSSKNAFPRSRSRQDIHISSHIHRDTSNSALLKILVITRTRLDSFVKT
SIO_010081: YBR072C-A
subclass of: SO_0000673
so part of: YBR072C-A
location: complement(382860..383021)
location: region:382860-383021:-1
so has part: feature:382860-383021:-1:exon

NP_878048.1
type: Protein
SIO_000068: ncbiprotein

S000028532
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:382860-383021:-1:exon

YBR073W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: TID1
gene: RDH54
locus tag: YBR073W
gene synonym: TID1
so part of: sequence
location: <383112..>385988
location: region:383112-385988:1
so has part: feature:383112-385988:1:exon
subclass of: SO_0000010

852365
type: Gene
SIO_000068: ncbigene

position:383112:1
position: 383112
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:385988:1
position: 385988
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:383112-385988:1:exon

YBR073W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: TID1
gene: RDH54
locus tag: YBR073W
gene synonym: TID1
product: DNA-dependent ATPase RDH54
transcript id: NM_001178421.4
SIO_010081: YBR073W
subclass of: SO_0000673
so part of: YBR073W
location: <383112..>385988
location: region:383112-385988:1
so has part: feature:383112-385988:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:383112-385988:1:exon

YBR073W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: TID1
gene: RDH54
locus tag: YBR073W
gene synonym: TID1
EC number: 3.6.4.12
experiment: EXISTENCE:curator inference:GO:0005634 nucleus [PMID:16831867]
experiment: EXISTENCE:direct assay:GO:0003690 double-stranded DNA binding [PMID:16831867]
experiment: EXISTENCE:direct assay:GO:0008094 ATP-dependent activity, acting on DNA [PMID:10970884]
experiment: EXISTENCE:direct assay:GO:0015616 DNA translocase activity [PMID:10970884]
experiment: EXISTENCE:direct assay:GO:0030491 heteroduplex formation [PMID:10970884]
experiment: EXISTENCE:direct assay:GO:0032392 DNA geometric change [PMID:10970884|PMID:16831867]
experiment: EXISTENCE:direct assay:GO:0032508 DNA duplex unwinding [PMID:16831867]
experiment: EXISTENCE:mutant phenotype:GO:0003690 double-stranded DNA binding [PMID:16831867]
experiment: EXISTENCE:mutant phenotype:GO:0006281 DNA repair [PMID:16831867]
experiment: EXISTENCE:mutant phenotype:GO:0006310 DNA recombination [PMID:16831867]
experiment: EXISTENCE:mutant phenotype:GO:0007131 reciprocal meiotic recombination [PMID:9409819|PMID:9409820]
experiment: EXISTENCE:mutant phenotype:GO:0008094 ATP-dependent activity, acting on DNA [PMID:16831867]
experiment: EXISTENCE:mutant phenotype:GO:0032392 DNA geometric change [PMID:16831867]
experiment: EXISTENCE:mutant phenotype:GO:0032508 DNA duplex unwinding [PMID:16831867]
experiment: EXISTENCE:mutant phenotype:GO:0045144 meiotic sister chromatid segregation [PMID:16230461]
note: DNA-dependent ATPase; DNA recombination/repair translocase, supercoils DNA, promotes DNA strand opening; stimulates strand exchange by modifying dsDNA topology; involved in recombinational repair of DNA double-strand breaks (DSBs) during mitosis, meiosis; implicated in cell divisions in telomerase-negative strains through adaptation to DNA damage, which allows bypass of cell cycle arrest and contributes senescence-specific genome instability; phosphorylated in response to DNA damage
codon start: 1
product: DNA-dependent ATPase RDH54
translation: MAVISVKPRRREKILQEVKNSSVYQTVFDSGTTQMQIPKYENKPFKPPRRVGSNKYTQLKPTATAVTTAPISKAKVTVNLKRSISAGPTLNLAKKPNNLSSNENTRYFTIMYRKPTTKKHKTWSGDGYATLKASSDKLCFYNEAGKFLGSSMLPSDSDSLFETLFKAGSNEVQLDYELKENAEIRSAKEALSQNMGNPSPPTTSTTETVPSTKNDGGKYQMPLSQLFSLNTVKRFKSVTKQTNEHMTTVPKTSQNSKAKKYYPVFDVNKIDNPIVMNKNAAAEVDVIVDPLLGKFLRPHQREGVKFMYDCLMGLARPTIENPDIDCTTKSLVLENDSDISGCLLADDMGLGKTLMSITLIWTLIRQTPFASKVSCSQSGIPLTGLCKKILVVCPVTLIGNWKREFGKWLNLSRIGVLTLSSRNSPDMDKMAVRNFLKVQRTYQVLIIGYEKLLSVSEELEKNKHLIDMLVCDEGHRLKNGASKILNTLKSLDIRRKLLLTGTPIQNDLNEFFTIIDFINPGILGSFASFKRRFIIPITRARDTANRYNEELLEKGEERSKEMIEITKRFILRRTNAILEKYLPPKTDIILFCKPYSQQILAFKDILQGARLDFGQLTFSSSLGLITLLKKVCNSPGLVGSDPYYKSHIKDTQSQDSYSRSLNSGKLKVLMTLLEGIRKGTKEKVVVVSNYTQTLDIIENLMNMAGMSHCRLDGSIPAKQRDSIVTSFNRNPAIFGFLLSAKSGGVGLNLVGASRLILFDNDWNPSVDLQAMSRIHRDGQKKPCFIYRLVTTGCIDEKILQRQLMKNSLSQKFLGDSEMRNKESSNDDLFNKEDLKDLFSVHTDTKSNTHDLICSCDGLGEEIEYPETNQQQNTVELRKRSTTTWTSALDLQKKMNEAATNDDAKKSQYIRQCLVHYKHIDPARQDELFDEVITDSFTELKDSITFAFVKPGEICLREQ
SIO_010081: YBR073W
subclass of: SO_0000673
so part of: YBR073W
location: 383112..385988
location: region:383112-385988:1
so has part: feature:383112-385988:1:exon

NP_009629.6
type: Protein
SIO_000068: ncbiprotein

S000000277
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:383112-385988:1:exon

YBR074W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YBR075W
gene: PFF1
locus tag: YBR074W
gene synonym: YBR075W
so part of: sequence
location: <386286..>389216
location: region:386286-389216:1
so has part: feature:386286-389216:1:exon
subclass of: SO_0000010

852366
type: Gene
SIO_000068: ncbigene

position:386286:1
position: 386286
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:389216:1
position: 389216
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:386286-389216:1:exon

YBR074W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YBR075W
gene: PFF1
locus tag: YBR074W
gene synonym: YBR075W
product: Pff1p
transcript id: NM_001178422.2
SIO_010081: YBR074W
subclass of: SO_0000673
so part of: YBR074W
location: <386286..>389216
location: region:386286-389216:1
so has part: feature:386286-389216:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:386286-389216:1:exon

YBR074W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YBR075W
gene: PFF1
locus tag: YBR074W
gene synonym: YBR075W
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:23679341|PMID:19001347|PMID:26928762]
note: Multi-spanning vacuolar membrane protease; glycosylated transmembrane protein bearing homology to M28 family of metalloproteases; has lumenal-facing protease domain; proposed role in vacuole physiology; targeted to vacuole via AP-3 pathway
codon start: 1
product: Pff1p
translation: MKLKSVFRSVLKYRKTNLSLLLLITYSIITLLYIFDHERYKLNLPKEDEHPEFNDLLETAWGDLQIITASFHPYTSKENDKVHDYLLKRVLEITGNSSFASVSDDKESERSILFQQQDPFNESSRFSRVTYFESSNILVKLEGKNPEEEGLLLSAHFDSVPTGYGATDDGMGVVSLLANLKYHIKHRPNRTLIFNFNNNEEFGLLGASTYFDHSWSNLTKYVINLEGTGAGGKAVLFRTSDTSTARIYQQSVKENPFGNSIYQQGFYSRYVRSETDYKIYEENGMRGWDVAFYKPRNLYHTIKDSIQYTSKASLWHMLHTSLQLSAYVASNSLDTADQTPACYFDFIGLKFFVISAKTLFYWNCIFLLVSPVVAIGLYLISRDRMTWKSYSWLSWTRFPLSLAAGIIVQKLFSNDIIRSNPLTFSRNYFWPISAFFTQVIFTSYVLINCSNFFFPCADMKSLSIIELFIILWTILLFTSKLLYSSDYRYTGLYPLSIFFLLSTIAAILRLLALALGMRTRKRLGRECRDHHSNYSSHSQIDMERDGQENLEQPQDQLTSSQDDQASIQDDNVSTTSAGPSHNVDEDHGMDSSSQQHDERVPLLKGSNSMEEGLSTRENSLKLEYTDYAWIIQFLLIVPIPSFILFNSVDVIMDALNHTVQEGSKATFDVLRFGMVGSILIALPILPFFYKVNYITISLTALLFLISASKTLLVHPFTNSNPLKVRFSQNIDLSQGNAASVHVLGREGNFLKPMLQDLPSIKYSSTHINCTSVTNGMELCMYDGMQPNLLSTNGNTNISSMVKVHVLHNNRNSTERSPYEPIVAELLLEVKENRACTLTFESRHQAKSPVREITVYQKKNSAPQKANITKTIKSASGINELQLHKLDFDQETYHIGVQWFPKLLTDGNVEDDKLGTKDELSVSISCYWGEYDSESVVNGTAVRKIPAFDELINYAPLSFSFTNEQKGLVIVKDAIIL
SIO_010081: YBR074W
subclass of: SO_0000673
so part of: YBR074W
location: 386286..389216
location: region:386286-389216:1
so has part: feature:386286-389216:1:exon

NP_009630.3
type: Protein
SIO_000068: ncbiprotein

S000000278
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:386286-389216:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS213; Autonomously Replicating Sequence
so part of: sequence
location: 389212..390371
location: region:389212-390371:1
so has part: feature:389212-390371:1:region

S000130152
type: SGD
SIO_000068: sgd

position:389212:1
position: 389212
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:390371:1
position: 390371
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:389212-390371:1:region

YBR076W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ECM8
locus tag: YBR076W
so part of: sequence
location: <390227..>391291
location: region:390227-391291:1
so has part: feature:390227-391291:1:exon
subclass of: SO_0000010

852368
type: Gene
SIO_000068: ncbigene

position:390227:1
position: 390227
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:391291:1
position: 391291
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:390227-391291:1:exon

YBR076W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ECM8
locus tag: YBR076W
product: Ecm8p
transcript id: NM_001178424.2
SIO_010081: YBR076W
subclass of: SO_0000673
so part of: YBR076W
location: <390227..>391291
location: region:390227-391291:1
so has part: feature:390227-391291:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:390227-391291:1:exon

YBR076W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ECM8
locus tag: YBR076W
note: Non-essential hypothetical protein
codon start: 1
product: Ecm8p
translation: MDYGYFFPAQRIEETNGVDFWIDSNAEFTQSKRPDSSTSTLSRVLTDTTNVSNNSGSLKRKTIKNKIFPQRKIFNDSENFDFGKANTDCKHVFKSISKQLIFLPRCFQHHSIRGWMKDRYSEFGYKIKRNQNCPPSACVQALYNTSRSNTEESNPNSLDSLIMYKYMRYSEKKKELMCRFCQGNNWILAENYLKHLFFAHGILSEFKPHTLYHFESKLLKIQGKLNFKIQVLKEPEFSKKILNSLTVSIIPSPLAYYTQTLNGGFRRIHVKCPHCENWIRLGWCEYDEIIRDSFQDFESLRNLNADYNGMSYIQTRNREDIEGIYENYFTHYIQCDLATFRTKCLYVQVITKSN
SIO_010081: YBR076W
subclass of: SO_0000673
so part of: YBR076W
location: 390227..391291
location: region:390227-391291:1
so has part: feature:390227-391291:1:exon

NP_009632.2
type: Protein
SIO_000068: ncbiprotein

S000000280
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:390227-391291:1:exon

YBR077C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: EGO3
alternative label: GSE1
alternative label: NIR1
gene: SLM4
locus tag: YBR077C
gene synonym: EGO3; GSE1; NIR1
so part of: sequence
location: complement(<391805..>392293)
location: region:391805-392293:-1
so has part: feature:391805-392293:-1:exon
subclass of: SO_0000010

852369
type: Gene
SIO_000068: ncbigene

position:391805:-1
position: 391805
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:392293:-1
position: 392293
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:391805-392293:-1:exon

YBR077C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: EGO3
alternative label: GSE1
alternative label: NIR1
gene: SLM4
locus tag: YBR077C
gene synonym: EGO3; GSE1; NIR1
product: Slm4p
transcript id: NM_001178425.3
SIO_010081: YBR077C
subclass of: SO_0000673
so part of: YBR077C
location: complement(<391805..>392293)
location: region:391805-392293:-1
so has part: feature:391805-392293:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:391805-392293:-1:exon

YBR077C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: EGO3
alternative label: GSE1
alternative label: NIR1
gene: SLM4
locus tag: YBR077C
gene synonym: EGO3; GSE1; NIR1
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:15989961|PMID:23708375|PMID:14562095|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0031902 late endosome membrane [PMID:16732272]
experiment: EXISTENCE:direct assay:GO:0071986 Ragulator complex [PMID:16732272]
experiment: EXISTENCE:mutant phenotype:GO:0007165 signal transduction [PMID:15539461]
experiment: EXISTENCE:mutant phenotype:GO:0016237 lysosomal microautophagy [PMID:15989961]
experiment: EXISTENCE:physical interaction:GO:0071986 Ragulator complex [PMID:15989961]
note: Subunit of EGO/GSE complex; vacuolar/endosomal membrane-associated EGO/GSE complex regulates exit from rapamycin-induced growth arrest, stimulating microautophagy and sorting of Gap1p from endosome to plasma membrane; essential for integrity and function of EGO; targeted to vacuole via AP-3 pathway; gene exhibits synthetic genetic interaction with MSS4
codon start: 1
product: Slm4p
translation: MVMLHSKNVKGFLENTLKPYDLHSVDFKTSSLQSSMIITATNGGILSYATSNNDVPKNSINEINSVNNLKMMSLLIKDKWSEDENDTEEQHSNSCYPVEIDSFKTKIYTYEMEDLHTCVAQIPNSDLLLLFIAEGSFPYGLLVIKIERAMRELTDLFGYKLG
SIO_010081: YBR077C
subclass of: SO_0000673
so part of: YBR077C
location: complement(391805..392293)
location: region:391805-392293:-1
so has part: feature:391805-392293:-1:exon

NP_009633.3
type: Protein
SIO_000068: ncbiprotein

S000000281
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:391805-392293:-1:exon

YBR078W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ECM33
locus tag: YBR078W
so part of: sequence
location: <393123..>394742
location: region:393123-394742:1
so has part: feature:393123-394742:1:exon
subclass of: SO_0000010

852370
type: Gene
SIO_000068: ncbigene

position:393123:1
position: 393123
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:394742:1
position: 394742
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:393123-394742:1:exon

YBR078W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ECM33
locus tag: YBR078W
product: Ecm33p
transcript id: NM_001178426.2
SIO_010081: YBR078W
subclass of: SO_0000673
so part of: YBR078W
location: join(<393123..393180,393511..>394742)
location: region:393123-394742:1
so has part: feature:393123-393180:1:exon
so has part: feature:393511-394742:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:393123-393180:1:exon

position:393180:1
position: 393180
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:393511-394742:1:exon

position:393511:1
position: 393511
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YBR078W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ECM33
locus tag: YBR078W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239|PMID:14576278]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:12583915|PMID:16622836]
experiment: EXISTENCE:direct assay:GO:0009277 fungal-type cell wall [PMID:15781460]
experiment: EXISTENCE:mutant phenotype:GO:0031505 fungal-type cell wall organization [PMID:15583168]
note: GPI-anchored protein involved in efficient glucose uptake; possible role in apical bud growth; GPI-anchoring on the plasma membrane crucial to function; phosphorylated in mitochondria; similar to Sps2p; ECM33 has a paralog, PST1, that arose from the whole genome duplication
codon start: 1
product: Ecm33p
translation: MQFKNALTATAILSASALAANSTTSIPSSCSIGTSATATAQADLDKISGCSTIVGNLTITGDLGSAALASIQEIDGSLTIFNSSSLSSFSADSIKKITGDLNMQELIILTSASFGSLQEVDSINMVTLPAISTFSTDLQNANNIIVSDTTLESVEGFSTLKKVNVFNINNNRYLNSFQSSLESVSDSLQFSSNGDNTTLAFDNLVWANNITLRDVNSISFGSLQTVNASLGFINNTLPSLNLTQLSKVGQSLSIVSNDELSKAAFSNLTTVGGGFIIANNTQLKVIDGFNKVQTVGGAIEVTGNFSTLDLSSLKSVRGGANFDSSSSNFSCNALKKLQSNGAIQGDSFVCKNGATSTSVKLSSTSTESSKSSATSSASSSGDASNAQANVSASASSSSSSSKKSKGAAPELVPATSFMGVVAAVGVALL
SIO_010081: YBR078W
subclass of: SO_0000673
so part of: YBR078W
location: join(393123..393180,393511..394742)
location: region:393123-394742:1
so has part: feature:393123-393180:1:exon
so has part: feature:393511-394742:1:exon

NP_009634.2
type: Protein
SIO_000068: ncbiprotein

S000000282
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:393123-393180:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:393511-394742:1:exon

YBR079C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: TIF32
gene: RPG1
locus tag: YBR079C
gene synonym: TIF32
so part of: sequence
location: complement(<395383..>398277)
location: region:395383-398277:-1
so has part: feature:395383-398277:-1:exon
subclass of: SO_0000010

852371
type: Gene
SIO_000068: ncbigene

position:395383:-1
position: 395383
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:398277:-1
position: 398277
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:395383-398277:-1:exon

YBR079C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: TIF32
gene: RPG1
locus tag: YBR079C
gene synonym: TIF32
product: translation initiation factor eIF3 core subunit a
transcript id: NM_001178427.1
SIO_010081: YBR079C
subclass of: SO_0000673
so part of: YBR079C
location: complement(<395383..>398277)
location: region:395383-398277:-1
so has part: feature:395383-398277:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:395383-398277:-1:exon

YBR079C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: TIF32
gene: RPG1
locus tag: YBR079C
gene synonym: TIF32
experiment: EXISTENCE:direct assay:GO:0000131 incipient cellular bud site [PMID:11302750]
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0003743 translation initiation factor activity [PMID:9671501]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276|PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005852 eukaryotic translation initiation factor 3 complex [PMID:9671501]
experiment: EXISTENCE:direct assay:GO:0006413 translational initiation [PMID:9671501]
experiment: EXISTENCE:direct assay:GO:0010494 cytoplasmic stress granule [PMID:19470581|PMID:26777405]
experiment: EXISTENCE:direct assay:GO:0043614 multi-eIF complex [PMID:15838098]
experiment: EXISTENCE:mutant phenotype:GO:0002188 translation reinitiation [PMID:20679478]
experiment: EXISTENCE:physical interaction:GO:0005852 eukaryotic translation initiation factor 3 complex [PMID:9660829]
note: eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3); subunit of the core complex of eIF3; part of a Prt1p-Rpg1p-Nip1p subcomplex that stimulates binding of mRNA and tRNA(i)Met to ribosomes; essential for loading mRNA onto ribosome at entry and exit channels of preinitiation complex; involved in translation reinitiation; eIF3 is also involved in programmed stop codon readthrough
codon start: 1
product: translation initiation factor eIF3 core subunit a
translation: MAPPPFRPENAIKRADELISVGEKQAALQSLHDFITARRIRWATPSTVEPVVFKFLEIGVELKKGKLLKDGLHQYKKLIQGSTEGLVSVGAVARKFIDLVESKIASEQTRADELQKQEIDDDLEGGVTPENLLISVYESDQSVAGFNDEAITSWLRFTWESYRAVLDLLRNNALLEITYSGVVKKTMHFCLKYQRKNEFKRLAEMLRQHLDAANYQQSKSGNNLVDLSDADTLQRYLDQRFQQVDVSVKLELWHEAYRSIEDVFHLMKISKRAPKPSTLANYYENLVKVFFVSGDPLLHTTAWKKFYKLYSTNPRATEEEFKTYSSTIFLSAISTQLDEIPSIGYDPHLRMYRLLNLDAKPTRKEMLQSIIEDESIYGKVDEELKELYDIIEVNFDVDTVKQQLENLLVKLSSKTYFSQYIAPLRDVIMRRVFVAASQKFTTVSQSELYKLATLPAPLDLSAWDIEKSLLQAAVEDYVSITIDHESAKVTFAKDPFDIFASTASKEVSEEENTEPEVQEEKEETDEALGPQETEDGEEKEEESDPVIIRNSYIHNKLLELSNVLHDVDSFNNASYMEKVRIARETLIKKNKDDLEKISKIVDERVKRSQEQKQKHMEHAALHAEQDAEVRQQRILEEKAAIEAKLEEEAHRRLIEKKKREFEAIKEREITKMITEVNAKGHVYIDPNEAKSLDLDTIKQVIIAEVSKNKSELESRMEYAMKKLDHTERALRKVELPLLQKEVDKLQETDTANYEAMKKKIVDAAKAEYEARMADRKNLVMVYDDYLKFKEHVSGTKESELAAIRNQKKAELEAAKKARIEEVRKRRYEEAIARRKEEIANAERQKRAQELAEATRKQREIEEAAAKKSTPYSFRAGNREPPSTPSTLPKATVSPDKAKLDMIAQKQREMEEAIEQRLAGRTAGGSSPATPATPATPATPTPSSGPKKMTMAEKLRAKRLAKGGR
SIO_010081: YBR079C
subclass of: SO_0000673
so part of: YBR079C
location: complement(395383..398277)
location: region:395383-398277:-1
so has part: feature:395383-398277:-1:exon

NP_009635.1
type: Protein
SIO_000068: ncbiprotein

S000000283
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:395383-398277:-1:exon

YBR080C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ANU4
gene: SEC18
locus tag: YBR080C
gene synonym: ANU4
so part of: sequence
location: complement(<398614..>400890)
location: region:398614-400890:-1
so has part: feature:398614-400890:-1:exon
subclass of: SO_0000010

852372
type: Gene
SIO_000068: ncbigene

position:398614:-1
position: 398614
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:400890:-1
position: 400890
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:398614-400890:-1:exon

YBR080C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ANU4
gene: SEC18
locus tag: YBR080C
gene synonym: ANU4
product: AAA family ATPase SEC18
transcript id: NM_001178428.3
SIO_010081: YBR080C
subclass of: SO_0000673
so part of: YBR080C
location: complement(<398614..>400890)
location: region:398614-400890:-1
so has part: feature:398614-400890:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:398614-400890:-1:exon

YBR080C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ANU4
gene: SEC18
locus tag: YBR080C
gene synonym: ANU4
experiment: EXISTENCE:direct assay:GO:0000149 SNARE binding [PMID:27364524]
experiment: EXISTENCE:direct assay:GO:0005794 Golgi apparatus [PMID:23613772]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport [PMID:9382859]
experiment: EXISTENCE:direct assay:GO:0016887 ATP hydrolysis activity [PMID:10387016]
experiment: EXISTENCE:direct assay:GO:0035494 SNARE complex disassembly [PMID:18650938|PMID:9425154]
experiment: EXISTENCE:direct assay:GO:0042144 vacuole fusion, non-autophagic [PMID:8670830|PMID:9685264]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:19053807]
experiment: EXISTENCE:direct assay:GO:0048280 vesicle fusion with Golgi apparatus [PMID:9382859]
experiment: EXISTENCE:direct assay:GO:0070300 phosphatidic acid binding [PMID:27364524]
experiment: EXISTENCE:mutant phenotype:GO:0000045 autophagosome assembly [PMID:11694599]
experiment: EXISTENCE:mutant phenotype:GO:0016236 macroautophagy [PMID:11694599]
experiment: EXISTENCE:mutant phenotype:GO:0043001 Golgi to plasma membrane protein transport [PMID:2071670]
experiment: EXISTENCE:mutant phenotype:GO:0048219 inter-Golgi cisterna vesicle-mediated transport [PMID:10637300|PMID:2071670]
note: AAA ATPase and SNARE disassembly chaperone; required for vesicular transport between ER and Golgi, the 'priming' step in homotypic vacuole fusion, autophagy, and protein secretion; releases Sec17p from SNAP complexes; has similarity to mammalian N-ethylmaleimide-sensitive factor (NSF)
codon start: 1
product: AAA family ATPase SEC18
translation: MFKIPGFGKAAANHTPPDMTNMDTRTRHLKVSNCPNNSYALANVAAVSPNDFPNNIYIIIDNLFVFTTRHSNDIPPGTIGFNGNQRTWGGWSLNQDVQAKAFDLFKYSGKQSYLGSIDIDISFRARGKAVSTVFDQDELAKQFVRCYESQIFSPTQYLIMEFQGHFFDLKIRNVQAIDLGDIEPTSAVATGIETKGILTKQTQINFFKGRDGLVNLKSSNSLRPRSNAVIRPDFKFEDLGVGGLDKEFTKIFRRAFASRIFPPSVIEKLGISHVKGLLLYGPPGTGKTLIARKIGTMLNAKEPKIVNGPEILSKYVGSSEENIRNLFKDAEAEYRAKGEESSLHIIIFDELDSVFKQRGSRGDGTGVGDNVVNQLLAKMDGVDQLNNILVIGMTNRKDLIDSALLRPGRFEVQVEIHLPDEKGRLQIFDIQTKKMRENNMMSDDVNLAELAALTKNFSGAEIEGLVKSASSFAINKTVNIGKGATKLNTKDIAKLKVTREDFLNALNDVTPAFGISEEDLKTCVEGGMMLYSERVNSILKNGARYVRQVRESDKSRLVSLLIHGPAGSGKTALAAEIALKSGFPFIRLISPNELSGMSESAKIAYIDNTFRDAYKSPLNILVIDSLETLVDWVPIGPRFSNNILQMLKVALKRKPPQDRRLLIMTTTSAYSVLQQMDILSCFDNEIAVPNMTNLDELNNVMIESNFLDDAGRVKVINELSRSCPNFNVGIKKTLTNIETARHDEDPVNELVELMTQSA
SIO_010081: YBR080C
subclass of: SO_0000673
so part of: YBR080C
location: complement(398614..400890)
location: region:398614-400890:-1
so has part: feature:398614-400890:-1:exon

NP_009636.3
type: Protein
SIO_000068: ncbiprotein

S000000284
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:398614-400890:-1:exon

YBR081C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: GIT2
gene: SPT7
locus tag: YBR081C
gene synonym: GIT2
so part of: sequence
location: complement(<401253..>405251)
location: region:401253-405251:-1
so has part: feature:401253-405251:-1:exon
subclass of: SO_0000010

852373
type: Gene
SIO_000068: ncbigene

position:401253:-1
position: 401253
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:405251:-1
position: 405251
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:401253-405251:-1:exon

YBR081C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: GIT2
gene: SPT7
locus tag: YBR081C
gene synonym: GIT2
product: SAGA histone acetyltransferase complex subunit SPT7
transcript id: NM_001178429.1
SIO_010081: YBR081C
subclass of: SO_0000673
so part of: YBR081C
location: complement(<401253..>405251)
location: region:401253-405251:-1
so has part: feature:401253-405251:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:401253-405251:-1:exon

YBR081C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: GIT2
gene: SPT7
locus tag: YBR081C
gene synonym: GIT2
experiment: EXISTENCE:direct assay:GO:0000124 SAGA complex [PMID:9224714|PMID:9674426]
experiment: EXISTENCE:direct assay:GO:0005198 structural molecule activity [PMID:12101232]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0006325 chromatin organization [PMID:9674426]
experiment: EXISTENCE:direct assay:GO:0046695 SLIK (SAGA-like) complex [PMID:12446794]
experiment: EXISTENCE:mutant phenotype:GO:0000747 conjugation with cellular fusion [PMID:7713415]
experiment: EXISTENCE:mutant phenotype:GO:0005198 structural molecule activity [PMID:9858534]
experiment: EXISTENCE:mutant phenotype:GO:0065003 protein-containing complex assembly [PMID:12101232|PMID:9858534]
note: Subunit of the SAGA transcriptional regulatory complex; involved in proper assembly of the complex; also present as a C-terminally truncated form in the SLIK/SALSA transcriptional regulatory complex
codon start: 1
product: SAGA histone acetyltransferase complex subunit SPT7
translation: MTERIPIKNYQRTNAKALLKLTEKLFNKNFFDLYLTSQQLVVLEYLLSISSEEDKLKAWDYFLKGNIALNVEKSFPLTQEEEHHGAVSPAVDTRSDDVSSQTIKDNNNTNTNTSISNENHVENEIEDKGDNAIANEDNFVNNDESDNVEEDLFKLDLEDLKQQISGTRFIGNLSLKIRYVLWQCAIDYIYCDRNEFGDENDTEYTLLDVEEKEEEEIGKNEKPQNKEGISKFAEDEDYDDEDENYDEDSTDVKNVDDPPKNLDSISSSNIEIDDERRLVLNISISKETLSKLKTNNVEEIMGNWNKIYHSFEYDKETMIKRLKLEESDKMIEKGKKKRSRSDLEAATDEQDRENTNDEPDTNQKLPTPEGSTFSDTGNKRPKQSNLDLTVNLGIENLSLKHLLSSIQQKKSQLGISDYELKHLIMDVRKNRSKWTSDERIGQEELYEACEKVVLELRNYTEHSTPFLNKVSKREAPNYHQIIKKSMDLNTVLKKLKSFQYDSKQEFVDDIMLIWKNCLTYNSDPSHFLRGHAIAMQKKSLQLIRMIPNITIRNRADLEKEIEDMEKDKDYELDEEEEVAGSGRKGLNMGAHMLAKENGKVSEKDSSKTVKDEAPTNDDKLTSVIPEGEKEKDKTASSTVTVHENVNKNEIKENGKNEEQDMVEESSKTEDSSKDADAAKKDTEDGLQDKTAENKEAGENNEEEEDDDDEDEDEDMVDSQSYLLEKDDDRDDLEISVWKTVTAKVRAEICLKRTEYFKNGKLNSDSEAFLKNPQRMKRFDQLFLEYKEQKALESYRQKIEQNSIMKNGFGTVLKQEDDDQLQFHNDHSLNGNEAFEKQPNDIELDDTRFLQEYDISNAIPDIVYEGVNTKTLDKMEDASVDRMLQNGINKQSRFLANKDLGLTPKMNQNITLIQQIRHICHKISLIRMLQSPLSAQNSRSNPNAFLNNHIYNYTIIDDSLDIDPVSQLPTHDYKNNRELIWKFMHKNISKVAMANGFETAHPSAINMLTEIAGDYLSNLIKTLKLHHETNSLNRGTNVEMLQTTLLENGINRPDDLFSYVESEFGKKTKKLQDIKQKLESFLRALLRPTLQELSERNFEDESQSFFTGDFASELTGEDFFGFRELGLEKEFGVLSSSVPLQLLTTQFQTVDGETKVQAKKIQPEESDSIVYKKITKGMLDAGSFWNTLLPLLQKDYERSKAYIAKQSKSSANDKTSMTSTEDNSFALLEEDQFVSKKTATKARLPPTGKISTTYKKKPIASAFILPEEDLENDVKADPTTTVNAKVGAENDGDSSLFLRTPQPLDPLDMDDAFDDTNMGSNSSFSLSLPRLNQ
SIO_010081: YBR081C
subclass of: SO_0000673
so part of: YBR081C
location: complement(401253..405251)
location: region:401253-405251:-1
so has part: feature:401253-405251:-1:exon

NP_009637.1
type: Protein
SIO_000068: ncbiprotein

S000000285
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:401253-405251:-1:exon

YNCB0015W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCB0015W
so part of: sequence
location: 405878..405949
location: region:405878-405949:1
so has part: feature:405878-405949:1:exon
subclass of: SO_0000663

852374
type: Gene
SIO_000068: ncbigene

position:405878:1
position: 405878
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:405949:1
position: 405949
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:405878-405949:1:exon

YNCB0015W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCB0015W
product: tRNA-Arg
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Arginine tRNA (tRNA-Arg), predicted by tRNAscan-SE analysis; one of 11 nuclear tRNA genes containing the tDNA-anticodon UCU (converted to mcm5-UCU in the mature tRNA); decodes AGA codons into arginine; one of 19 nuclear tRNAs for arginine; part of dicistronic transcript with tD(GUC)B
SIO_010081: YNCB0015W
subclass of: SO_0000673
so part of: YNCB0015W
location: 405878..405949
location: region:405878-405949:1
so has part: feature:405878-405949:1:exon

S000006708
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:405878-405949:1:exon

YNCB0016W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCB0016W
so part of: sequence
location: 405960..406031
location: region:405960-406031:1
so has part: feature:405960-406031:1:exon
subclass of: SO_0000663

852375
type: Gene
SIO_000068: ncbigene

position:405960:1
position: 405960
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:406031:1
position: 406031
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:405960-406031:1:exon

YNCB0016W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCB0016W
product: tRNA-Asp
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Aspartate tRNA (tRNA-Asp), predicted by tRNAscan-SE analysis
SIO_010081: YNCB0016W
subclass of: SO_0000673
so part of: YNCB0016W
location: 405960..406031
location: region:405960-406031:1
so has part: feature:405960-406031:1:exon

S000006530
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:405960-406031:1:exon

YBR082C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: UBC4
locus tag: YBR082C
so part of: sequence
location: complement(<406628..>407169)
location: region:406628-407169:-1
so has part: feature:406628-407169:-1:exon
subclass of: SO_0000010

852376
type: Gene
SIO_000068: ncbigene

position:406628:-1
position: 406628
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:407169:-1
position: 407169
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:406628-407169:-1:exon

YBR082C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: UBC4
locus tag: YBR082C
product: E2 ubiquitin-conjugating protein UBC4
transcript id: NM_001178430.1
SIO_010081: YBR082C
subclass of: SO_0000673
so part of: YBR082C
location: complement(join(<406628..407027,407123..>407169))
location: region:406628-407169:-1
so has part: feature:407123-407169:-1:exon
so has part: feature:406628-407027:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:407123-407169:-1:exon

position:407123:-1
position: 407123
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:406628-407027:-1:exon

position:407027:-1
position: 407027
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YBR082C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: UBC4
locus tag: YBR082C
EC number: 2.3.2.23
experiment: EXISTENCE:direct assay:GO:0000209 protein polyubiquitination [PMID:2154373|PMID:24034674]
experiment: EXISTENCE:direct assay:GO:0004842 ubiquitin-protein transferase activity [PMID:2154373]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:20598539]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:20598539]
experiment: EXISTENCE:direct assay:GO:0006513 protein monoubiquitination [PMID:8391479]
experiment: EXISTENCE:direct assay:GO:0016567 protein ubiquitination [PMID:16926149]
experiment: EXISTENCE:direct assay:GO:0030674 protein-macromolecule adaptor activity [PMID:11788821]
experiment: EXISTENCE:direct assay:GO:0043130 ubiquitin binding [PMID:21357418]
experiment: EXISTENCE:direct assay:GO:0070628 proteasome binding [PMID:10848595]
experiment: EXISTENCE:mutant phenotype:GO:0000209 protein polyubiquitination [PMID:32009536]
experiment: EXISTENCE:mutant phenotype:GO:0043130 ubiquitin binding [PMID:21357418]
experiment: EXISTENCE:mutant phenotype:GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [PMID:11788821]
experiment: EXISTENCE:mutant phenotype:GO:0071629 cytoplasm protein quality control by the ubiquitin-proteasome system [PMID:20462952]
experiment: EXISTENCE:mutant phenotype:GO:0072671 mitochondria-associated ubiquitin-dependent protein catabolic process [PMID:32118579]
note: Ubiquitin-conjugating enzyme (E2); key E2 partner with Ubc1p for the anaphase-promoting complex (APC); mediates degradation of abnormal or excess proteins, including calmodulin and histone H3; regulates levels of DNA Polymerase-{alpha} to promote efficient and accurate DNA replication; interacts with many SCF ubiquitin protein ligases; component of the cellular stress response; UBC4 has a paralog, UBC5, that arose from the whole genome duplication
codon start: 1
product: E2 ubiquitin-conjugating protein UBC4
translation: MSSSKRIAKELSDLERDPPTSCSAGPVGDDLYHWQASIMGPADSPYAGGVFFLSIHFPTDYPFKPPKISFTTKIYHPNINANGNICLDILKDQWSPALTLSKVLLSICSLLTDANPDDPLVPEIAHIYKTDRPKYEATAREWTKKYAV
SIO_010081: YBR082C
subclass of: SO_0000673
so part of: YBR082C
location: complement(join(406628..407027,407123..407169))
location: region:406628-407169:-1
so has part: feature:407123-407169:-1:exon
so has part: feature:406628-407027:-1:exon

NP_009638.1
type: Protein
SIO_000068: ncbiprotein

S000000286
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:407123-407169:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:406628-407027:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS214; Autonomously Replicating Sequence
so part of: sequence
location: 407953..408068
location: region:407953-408068:1
so has part: feature:407953-408068:1:region

S000118348
type: SGD
SIO_000068: sgd

position:407953:1
position: 407953
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:408068:1
position: 408068
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:407953-408068:1:region

YBR083W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ROC1
gene: TEC1
locus tag: YBR083W
gene synonym: ROC1
so part of: sequence
location: <409169..>410629
location: region:409169-410629:1
so has part: feature:409169-410629:1:exon
subclass of: SO_0000010

852377
type: Gene
SIO_000068: ncbigene

position:409169:1
position: 409169
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:410629:1
position: 410629
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:409169-410629:1:exon

YBR083W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ROC1
gene: TEC1
locus tag: YBR083W
gene synonym: ROC1
product: Tec1p
transcript id: NM_001178431.3
SIO_010081: YBR083W
subclass of: SO_0000673
so part of: YBR083W
location: <409169..>410629
location: region:409169-410629:1
so has part: feature:409169-410629:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:409169-410629:1:exon

YBR083W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ROC1
gene: TEC1
locus tag: YBR083W
gene synonym: ROC1
experiment: EXISTENCE:direct assay:GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding [PMID:20118212]
experiment: EXISTENCE:direct assay:GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific [PMID:9036858]
experiment: EXISTENCE:direct assay:GO:0003700 DNA-binding transcription factor activity [PMID:10652102]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:19218425]
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:19111667]
experiment: EXISTENCE:direct assay:GO:0045893 positive regulation of DNA-templated transcription [PMID:10652102]
experiment: EXISTENCE:direct assay:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:9036858]
experiment: EXISTENCE:direct assay:GO:1990527 Tec1p-Ste12p-Dig1p complex [PMID:16782869]
experiment: EXISTENCE:direct assay:GO:2000222 positive regulation of pseudohyphal growth [PMID:9036858]
experiment: EXISTENCE:genetic interaction:GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific [PMID:16782869]
experiment: EXISTENCE:mutant phenotype:GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific [PMID:16782869]
experiment: EXISTENCE:mutant phenotype:GO:0001403 invasive growth in response to glucose limitation [PMID:12455687]
experiment: EXISTENCE:mutant phenotype:GO:0007124 pseudohyphal growth [PMID:8730867|PMID:9036858|PMID:9055077]
experiment: EXISTENCE:mutant phenotype:GO:0010527 positive regulation of transposition, RNA-mediated [PMID:10652102]
note: Transcription factor targeting filamentation genes and Ty1 expression; Ste12p activation of most filamentation gene promoters depends on Tec1p and Tec1p transcriptional activity is dependent on its association with Ste12p; binds to TCS elements upstream of filamentation genes, which are regulated by Tec1p/Ste12p/Dig1p complex; competes with Dig2p for binding to Ste12p/Dig1p; positive regulator of chronological life span; TEA/ATTS DNA-binding domain family member
codon start: 1
product: Tec1p
translation: MSLKEDDFGKDNSRNIESYTGRIFDVYIQKDSYSQSALDDMFPEAVVSTAACVKNEAEDNINLIDTHPQFELVNTGLGAKSDDLKSPSAKATFTDKQRKNEVPNISVSNYFPGQSSETSSTTESWTIGCDKWSEKVEEAFLEALRLIMKNGTTKIKIRNANFGRNELISLYIKHKTNEFRTKKQISSHIQVWKKTIQNKIKDSLTLSSKEKELLHLIEHGAEQTTENSNLFYDIFEEIIDSLPSVSDSGSLTPKNLYVSNNSSGLSVHSKLLTPITASNEKKIENFIKTNAASQAKTPLIYAKHIYENIDGYKCVPSKRPLEQLSPTELHQGDRPNKASFSNKKAILESAKKIEIEQRKIINKYQRISRIQEHESNPEFSSNSNSGSEYESEEEVVPRSATVTQLQSRPVPYYKNNGMPYSLSKVRGRPMYPRPAEDAYNANYIQGLPQYQTSYFSQLLLSSPQHYEHSPHQRNFTPSNQSHGNFY
SIO_010081: YBR083W
subclass of: SO_0000673
so part of: YBR083W
location: 409169..410629
location: region:409169-410629:1
so has part: feature:409169-410629:1:exon

NP_009639.3
type: Protein
SIO_000068: ncbiprotein

S000000287
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:409169-410629:1:exon

YBR084W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MIS1
locus tag: YBR084W
so part of: sequence
location: <411054..>413981
location: region:411054-413981:1
so has part: feature:411054-413981:1:exon
subclass of: SO_0000010

852378
type: Gene
SIO_000068: ncbigene

position:411054:1
position: 411054
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:413981:1
position: 413981
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:411054-413981:1:exon

YBR084W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MIS1
locus tag: YBR084W
product: trifunctional formate-tetrahydrofolate ligase/methenyltetrahydrofolate cyclohydrolase/methylenetetrahydrofolate dehydrogenase MIS1
transcript id: NM_001178432.1
SIO_010081: YBR084W
subclass of: SO_0000673
so part of: YBR084W
location: <411054..>413981
location: region:411054-413981:1
so has part: feature:411054-413981:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:411054-413981:1:exon

YBR084W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MIS1
locus tag: YBR084W
EC number: 1.5.1.5
EC number: 3.5.4.9
EC number: 6.3.4.3
experiment: EXISTENCE:direct assay:GO:0004329 formate-tetrahydrofolate ligase activity [PMID:3528153]
experiment: EXISTENCE:direct assay:GO:0004477 methenyltetrahydrofolate cyclohydrolase activity [PMID:3528153]
experiment: EXISTENCE:direct assay:GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity [PMID:3528153]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:3528153|PMID:16823961|PMID:14576278|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0046656 folic acid biosynthetic process [PMID:3528153]
experiment: EXISTENCE:mutant phenotype:GO:0006139 nucleobase-containing compound metabolic process [PMID:10781559]
note: Mitochondrial C1-tetrahydrofolate synthase; involved in interconversion between different oxidation states of tetrahydrofolate (THF); provides activities of formyl-THF synthetase, methenyl-THF cyclohydrolase, and methylene-THF dehydrogenase
codon start: 1
product: trifunctional formate-tetrahydrofolate ligase/methenyltetrahydrofolate cyclohydrolase/methylenetetrahydrofolate dehydrogenase MIS1
translation: MLSRLSLLSNSRAFQQARWRIYRLKVSPTVHASQYHILSGRKLAQSIREKANDEIQAIKLKHPNFKPTLKIIQVGARPDSSTYVRMKLKASKDSNVDCIIEKLPAEITEVELLKKISDINDDDSIHGLLIQLPLPRHLDETTITNAVDFKKDVDGFHRYNAGELAKKGGKPYFIPCTPYGCMKLLEEAHVKLDGKNAVVLGRSSIVGNPIASLLKNANATVTVCHSHTRNIAEVVSQADIVIAACGIPQYVKSDWIKEGAVVIDVGINYVPDISKKSGQKLVGDVDFDSVKEKTSYITPVPGGVGPMTVAMLVSNVLLAAKRQFVESEKLPVIKPLPLHLESPVPSDIDISRAQSPKHIKQVAEELGIHSHELELYGHYKAKISPNIFKRLESRENGKYVLVAGITPTPLGEGKSTTTMGLVQALSAHLGKPSIANVRQPSLGPTLGVKGGAAGGGYAQVIPMDEFNLHLTGDIHAISAANNLLAAAIDTRMFHEATQKNDSTFYKRLVPRKKGIRKFTPSMQRRLKRLDIEKEDPDALTPEEVKRFARLNINPDTITIRRVVDINDRMLRQITIGEAATEKGFTRTTGFDITVASELMAILALSKSLHEMKERIGRMVIGADYDNKPVTVEDIGCTGALTALLRDAIKPNLMQTLEGTPVMVHAGPFANISIGASSVIADLMALKLVGSEKNPLNDKNIHEPGYVVTEAGFDFAMGGERFFDIKCRSSGLVPDAVVLVATVRALKSHGGAPNVKPGQSLPKEYTEENIDFVAKGVSNLVKQIENIKTFGIPVVVAINRFETDSQAEIEVIKKAALNAGASHAVTSNHWMEGGKGAVELAHAVVDATKEPKNFNFLYDVNSSIEDKLTSIVQKMYGGAKIEVSPEAQKKIDTYKKQGFGNLPICIAKTQYSLSHDPSLKGVPRGFTFPIRDVRASIGAGYLYALAAEIQTIPGLSTYAGYMAVEVDDDGEIEGLF
SIO_010081: YBR084W
subclass of: SO_0000673
so part of: YBR084W
location: 411054..413981
location: region:411054-413981:1
so has part: feature:411054-413981:1:exon

NP_009640.1
type: Protein
SIO_000068: ncbiprotein

S000000288
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:411054-413981:1:exon

YBR084C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RPL19A
locus tag: YBR084C-A
so part of: sequence
location: complement(<414186..>415261)
location: region:414186-415261:-1
so has part: feature:414186-415261:-1:exon
subclass of: SO_0000010

852379
type: Gene
SIO_000068: ncbigene

position:414186:-1
position: 414186
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:415261:-1
position: 415261
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:414186-415261:-1:exon

YBR084C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RPL19A
locus tag: YBR084C-A
product: ribosomal 60S subunit protein L19A
transcript id: NM_001180057.1
SIO_010081: YBR084C-A
subclass of: SO_0000673
so part of: YBR084C-A
location: complement(join(<414186..414753,415260..>415261))
location: region:414186-415261:-1
so has part: feature:415260-415261:-1:exon
so has part: feature:414186-414753:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:415260-415261:-1:exon

position:415260:-1
position: 415260
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:414186-414753:-1:exon

position:414753:-1
position: 414753
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YBR084C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RPL19A
locus tag: YBR084C-A
experiment: EXISTENCE:curator inference:GO:0002181 cytoplasmic translation [PMID:11983894]
experiment: EXISTENCE:curator inference:GO:0003735 structural constituent of ribosome [PMID:11983894]
experiment: EXISTENCE:direct assay:GO:0022625 cytosolic large ribosomal subunit [PMID:11983894]
note: Ribosomal 60S subunit protein L19A; rpl19a and rpl19b single null mutations result in slow growth, while the double null mutation is lethal; homologous to mammalian ribosomal protein L19, no bacterial homolog; RPL19A has a paralog, RPL19B, that arose from the whole genome duplication
codon start: 1
product: ribosomal 60S subunit protein L19A
translation: MANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIVKKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRVLRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQREKALNEEAEARRLKNRAARDRRAQRVAEKRDALLKEDA
SIO_010081: YBR084C-A
subclass of: SO_0000673
so part of: YBR084C-A
location: complement(join(414186..414753,415260..415261))
location: region:414186-415261:-1
so has part: feature:415260-415261:-1:exon
so has part: feature:414186-414753:-1:exon

NP_009641.1
type: Protein
SIO_000068: ncbiprotein

S000002156
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:415260-415261:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:414186-414753:-1:exon

YBR085W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ANC3
gene: AAC3
locus tag: YBR085W
gene synonym: ANC3
so part of: sequence
location: <415983..>416906
location: region:415983-416906:1
so has part: feature:415983-416906:1:exon
subclass of: SO_0000010

852380
type: Gene
SIO_000068: ncbigene

position:415983:1
position: 415983
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:416906:1
position: 416906
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:415983-416906:1:exon

YBR085W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ANC3
gene: AAC3
locus tag: YBR085W
gene synonym: ANC3
product: ADP/ATP carrier protein AAC3
transcript id: NM_001178433.3
SIO_010081: YBR085W
subclass of: SO_0000673
so part of: YBR085W
location: <415983..>416906
location: region:415983-416906:1
so has part: feature:415983-416906:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:415983-416906:1:exon

YBR085W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ANC3
gene: AAC3
locus tag: YBR085W
gene synonym: ANC3
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961]
experiment: EXISTENCE:genetic interaction:GO:0009061 anaerobic respiration [PMID:1915842|PMID:2165073]
experiment: EXISTENCE:mutant phenotype:GO:0015886 heme transport [PMID:18728780]
note: Mitochondrial inner membrane ADP/ATP translocator; exchanges cytosolic ADP for mitochondrially synthesized ATP; expressed under anaerobic conditions; similar to Aac1p; has roles in maintenance of viability and in respiration; AAC3 has a paralog, PET9, that arose from the whole genome duplication
codon start: 1
product: ADP/ATP carrier protein AAC3
translation: MSSDAKQQETNFAINFLMGGVSAAIAKTAASPIERVKILIQNQDEMIKQGTLDKKYSGIVDCFKRTAKQEGLISFWRGNTANVIRYFPTQALNFAFKDKIKLMFGFKKEEGYGKWFAGNLASGGAAGALSLLFVYSLDFARTRLAADAKSSKKGGARQFNGLTDVYKKTLKSDGIAGLYRGFMPSVVGIVVYRGLYFGMFDSLKPLVLTGSLDGSFLASFLLGWVVTTGASTCSYPLDTVRRRMMMTSGQAVKYNGAIDCLKKIVASEGVGSLFKGCGANILRSVAGAGVISMYDQLQMILFGKKFK
SIO_010081: YBR085W
subclass of: SO_0000673
so part of: YBR085W
location: 415983..416906
location: region:415983-416906:1
so has part: feature:415983-416906:1:exon

NP_009642.3
type: Protein
SIO_000068: ncbiprotein

S000000289
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:415983-416906:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS215; Autonomously Replicating Sequence; replication origin of very weak function
so part of: sequence
location: 417784..418079
location: region:417784-418079:1
so has part: feature:417784-418079:1:region

S000118349
type: SGD
SIO_000068: sgd

position:417784:1
position: 417784
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:418079:1
position: 418079
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:417784-418079:1:region

YBR085C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBR085C-A
so part of: sequence
location: complement(<418907..>419164)
location: region:418907-419164:-1
so has part: feature:418907-419164:-1:exon
subclass of: SO_0000010

852381
type: Gene
SIO_000068: ncbigene

position:418907:-1
position: 418907
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:419164:-1
position: 419164
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:418907-419164:-1:exon

YBR085C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBR085C-A
product: uncharacterized protein
transcript id: NM_001184443.1
SIO_010081: YBR085C-A
subclass of: SO_0000673
so part of: YBR085C-A
location: complement(<418907..>419164)
location: region:418907-419164:-1
so has part: feature:418907-419164:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:418907-419164:-1:exon

YBR085C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBR085C-A
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
note: hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to the nucleus; protein abundance increases in response to DNA replication stress
codon start: 1
product: uncharacterized protein
translation: MSSALYKQSTNFTHSTGSFLQSAPVELTTVSGYQEFLKKQEKKNYEIQTVLSEDKSHGYVLKDGEVIANIIGEAKDYLLDLAGQA
SIO_010081: YBR085C-A
subclass of: SO_0000673
so part of: YBR085C-A
location: complement(418907..419164)
location: region:418907-419164:-1
so has part: feature:418907-419164:-1:exon

NP_061491.1
type: Protein
SIO_000068: ncbiprotein

S000007522
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:418907-419164:-1:exon

YBR086C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: IST2
locus tag: YBR086C
so part of: sequence
location: complement(<420201..>423041)
location: region:420201-423041:-1
so has part: feature:420201-423041:-1:exon
subclass of: SO_0000010

852382
type: Gene
SIO_000068: ncbigene

position:420201:-1
position: 420201
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:423041:-1
position: 423041
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:420201-423041:-1:exon

YBR086C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: IST2
locus tag: YBR086C
product: Ist2p
transcript id: NM_001178434.1
SIO_010081: YBR086C
subclass of: SO_0000673
so part of: YBR086C
location: complement(<420201..>423041)
location: region:420201-423041:-1
so has part: feature:420201-423041:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:420201-423041:-1:exon

YBR086C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: IST2
locus tag: YBR086C
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:11030653|PMID:17234190]
experiment: EXISTENCE:direct assay:GO:0008289 lipid binding [PMID:19453974]
experiment: EXISTENCE:direct assay:GO:0032541 cortical endoplasmic reticulum [PMID:23237950]
experiment: EXISTENCE:direct assay:GO:0033101 cellular bud membrane [PMID:11030653|PMID:13679573]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0060304 regulation of phosphatidylinositol dephosphorylation [PMID:23237950]
experiment: EXISTENCE:genetic interaction:GO:0090158 endoplasmic reticulum membrane organization [PMID:23237950]
experiment: EXISTENCE:mutant phenotype:GO:0072659 protein localization to plasma membrane [PMID:24416406]
note: Cortical ER protein involved in ER-plasma membrane (PM) tethering; one of 6 proteins (Ist2, Scs2, Scs22, Tcb1, Tcb2, Tcb3) that connect ER to PM, regulate PM phosphatidylinositol-4-phosphate (PI4P) levels by controlling access of Sac1 phosphatase to PI4P; required to locate Osh6, Osh7 in ER/PM contact site to allow phosphatidylserine transport from ER to PM; localizes to mother in small-budded cells, to bud in medium-, large-budded cells; mRNA transported to bud tip by actomyosin-driven process
codon start: 1
product: Ist2p
translation: MSQTITSLDPNCVIVFNKTSSANEKSLNVEFKRLNIHSIIEPGHDLQTSYAFIRIHQDNAKPLFSFLQNLDFIESIIPYHDTELSDDLHKLISISKSKILEAPKQYELYNLSNLTNNPKQSLYFAFLQNYIKWLIPFSFFGLSIRFLSNFTYEFNSTYSLFAILWTLSFTAFWLYKYEPFWSDRLSKYSSFSTIEFLQDKQKAQKKASSVIMLKKCCFIPVALLFGAILLSFQLYCFALEIFIKQIYNGPMISILSFLPTILICTFTPVLTVIYNKYFVEPMTKWENHSSVVNAKKSKEAKNFVIIFLSSYVPLLITLFLYLPMGHLLTAEIRTKVFNAFSILARLPTHDSDFIIDTKRYEDQFFYFIVINQLIQFSMENFVPSLVSIAQQKINGPNPNFVKAESEIGKAQLSSSDMKIWSKVKSYQTDPWGATFDLDANFKKLLLQFGYLVMFSTIWPLAPFICLIVNLIVYQVDLRKAVLYSKPEYFPFPIYDKPSSVSNTQKLTVGLWNSVLVMFSILGCVITATLTYMYQSCNIPGVGAHTSIHTNKAWYLANPINHSWINIVLYAVFIEHVSVAIFFLFSSILKSSHDDVANGIVPKHVVNVQNPPKQEVFEKIPSPEFNSNNEKELVQRKGSANEKLHQELGEKQPASSANGYEAHAATHANNDPSSLSSASSPSLSSSSSSSKTGVVKAVDNDTAGSAGKKPLATESTEKRNSLVKVPTVGSYGVAGATLPETIPTSKNYYLRFDEDGKSIRDAKSSAESSNATNNNTLGTESKLLPDGDAVDALSRKIDQIPKIAVTGGENNENTQAKDDAATKTPLIKDANIKPVVNAAVNDNQSKVSVATEQTKKTEVSTKNGPSRSISTKETKDSARPSNNNTTTTTTTDATQPHHHHHHHRHRDAGVKNVTNNSKTTESSSSSSAAKEKPKHKKGLLHKLKKKL
SIO_010081: YBR086C
subclass of: SO_0000673
so part of: YBR086C
location: complement(420201..423041)
location: region:420201-423041:-1
so has part: feature:420201-423041:-1:exon

NP_009643.2
type: Protein
SIO_000068: ncbiprotein

S000000290
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:420201-423041:-1:exon

YBR087W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RFC5
locus tag: YBR087W
so part of: sequence
location: <423765..>424829
location: region:423765-424829:1
so has part: feature:423765-424829:1:exon
subclass of: SO_0000010

852383
type: Gene
SIO_000068: ncbigene

position:423765:1
position: 423765
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:424829:1
position: 424829
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:423765-424829:1:exon

YBR087W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RFC5
locus tag: YBR087W
product: replication factor C subunit 5
transcript id: NM_001178435.3
SIO_010081: YBR087W
subclass of: SO_0000673
so part of: YBR087W
location: <423765..>424829
location: region:423765-424829:1
so has part: feature:423765-424829:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:423765-424829:1:exon

YBR087W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RFC5
locus tag: YBR087W
experiment: EXISTENCE:direct assay:GO:0003689 DNA clamp loader activity [PMID:12604797|PMID:8995429]
experiment: EXISTENCE:direct assay:GO:0005663 DNA replication factor C complex [PMID:7651383]
experiment: EXISTENCE:direct assay:GO:0006272 leading strand elongation [PMID:1346062]
experiment: EXISTENCE:direct assay:GO:0031389 Rad17 RFC-like complex [PMID:12604797]
experiment: EXISTENCE:mutant phenotype:GO:0005663 DNA replication factor C complex [PMID:8559655]
experiment: EXISTENCE:mutant phenotype:GO:0007062 sister chromatid cohesion [PMID:12665596]
experiment: EXISTENCE:physical interaction:GO:0031389 Rad17 RFC-like complex [PMID:10660302]
experiment: EXISTENCE:physical interaction:GO:0031390 Ctf18 RFC-like complex [PMID:11389843]
experiment: EXISTENCE:physical interaction:GO:0031391 Elg1 RFC-like complex [PMID:12909721|PMID:12912927]
note: Subunit of heteropentameric Replication factor C (RF-C); RF-C is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon
codon start: 1
product: replication factor C subunit 5
translation: MSLWVDKYRPKSLNALSHNEELTNFLKSLSDQPRDLPHLLLYGPNGTGKKTRCMALLESIFGPGVYRLKIDVRQFVTASNRKLELNVVSSPYHLEITPSDMGNNDRIVIQELLKEVAQMEQVDFQDSKDGLAHRYKCVIINEANSLTKDAQAALRRTMEKYSKNIRLIMVCDSMSPIIAPIKSRCLLIRCPAPSDSEISTILSDVVTNERIQLETKDILKRIAQASNGNLRVSLLMLESMALNNELALKSSSPIIKPDWIIVIHKLTRKIVKERSVNSLIECRAVLYDLLAHCIPANIILKELTFSLLDVETLNTTNKSSIIEYSSVFDERLSLGNKAIFHLEGFIAKVMCCLD
SIO_010081: YBR087W
subclass of: SO_0000673
so part of: YBR087W
location: 423765..424829
location: region:423765-424829:1
so has part: feature:423765-424829:1:exon

NP_009644.3
type: Protein
SIO_000068: ncbiprotein

S000000291
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:423765-424829:1:exon

YBR088C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: POL30
locus tag: YBR088C
so part of: sequence
location: complement(<424990..>425766)
location: region:424990-425766:-1
so has part: feature:424990-425766:-1:exon
subclass of: SO_0000010

852385
type: Gene
SIO_000068: ncbigene

position:424990:-1
position: 424990
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:425766:-1
position: 425766
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:424990-425766:-1:exon

YBR088C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: POL30
locus tag: YBR088C
product: proliferating cell nuclear antigen
transcript id: NM_001178436.1
SIO_010081: YBR088C
subclass of: SO_0000673
so part of: YBR088C
location: complement(<424990..>425766)
location: region:424990-425766:-1
so has part: feature:424990-425766:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:424990-425766:-1:exon

YBR088C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: POL30
locus tag: YBR088C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:15282802]
experiment: EXISTENCE:direct assay:GO:0005657 replication fork [PMID:12015307]
experiment: EXISTENCE:direct assay:GO:0006272 leading strand elongation [PMID:1682321]
experiment: EXISTENCE:direct assay:GO:0006273 lagging strand elongation [PMID:7673186]
experiment: EXISTENCE:direct assay:GO:0030337 DNA polymerase processivity factor activity [PMID:18635534|PMID:2902631]
experiment: EXISTENCE:direct assay:GO:1902394 positive regulation of exodeoxyribonuclease activity [PMID:12192046]
experiment: EXISTENCE:direct assay:GO:1903022 positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands [PMID:12192046]
experiment: EXISTENCE:direct assay:GO:1905779 positive regulation of exonuclease activity [PMID:30778235]
experiment: EXISTENCE:genetic interaction:GO:0000278 mitotic cell cycle [PMID:7516465]
experiment: EXISTENCE:genetic interaction:GO:0000710 meiotic mismatch repair [PMID:18245822]
experiment: EXISTENCE:genetic interaction:GO:0006298 mismatch repair [PMID:8910404|PMID:9504910]
experiment: EXISTENCE:genetic interaction:GO:0006301 postreplication repair [PMID:8790390]
experiment: EXISTENCE:genetic interaction:GO:0007064 mitotic sister chromatid cohesion [PMID:16934511]
experiment: EXISTENCE:genetic interaction:GO:0030466 silent mating-type cassette heterochromatin formation [PMID:10545450]
experiment: EXISTENCE:genetic interaction:GO:0034087 establishment of mitotic sister chromatid cohesion [PMID:16934511]
experiment: EXISTENCE:genetic interaction:GO:0035753 maintenance of DNA trinucleotide repeats [PMID:16079237]
experiment: EXISTENCE:genetic interaction:GO:0070987 error-free translesion synthesis [PMID:19264809]
experiment: EXISTENCE:mutant phenotype:GO:0000710 meiotic mismatch repair [PMID:18245822]
experiment: EXISTENCE:mutant phenotype:GO:0006289 nucleotide-excision repair [PMID:9806417]
experiment: EXISTENCE:mutant phenotype:GO:0006298 mismatch repair [PMID:8858149]
experiment: EXISTENCE:mutant phenotype:GO:0006301 postreplication repair [PMID:8790390]
experiment: EXISTENCE:mutant phenotype:GO:0030466 silent mating-type cassette heterochromatin formation [PMID:16157874]
experiment: EXISTENCE:mutant phenotype:GO:0031509 subtelomeric heterochromatin formation [PMID:16157874]
experiment: EXISTENCE:mutant phenotype:GO:0035753 maintenance of DNA trinucleotide repeats [PMID:16079237]
experiment: EXISTENCE:physical interaction:GO:0006273 lagging strand elongation [PMID:7673186]
experiment: EXISTENCE:physical interaction:GO:0006298 mismatch repair [PMID:8858149]
experiment: EXISTENCE:physical interaction:GO:0007064 mitotic sister chromatid cohesion [PMID:16934511]
experiment: EXISTENCE:physical interaction:GO:0043626 PCNA complex [PMID:8001157]
note: Proliferating cell nuclear antigen (PCNA); functions as the sliding replication clamp for DNA polymerase delta; may function as a docking site for other proteins required for mitotic and meiotic chromosomal DNA replication and for DNA repair; PCNA ubiquitination at K164 plays a crucial role during Okazaki fragment processing; leucine at position 164 is essential for stable complex formation with replicative DNA polymerase delta
codon start: 1
product: proliferating cell nuclear antigen
translation: MLEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEYRCDHPVTLGMDLTSLSKILRCGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLKLMDIDADFLKIEELQYDSTLSLPSSEFSKIVRDLSQLSDSINIMITKETIKFVADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFDLKSGFLQFFLAPKFNDEE
SIO_010081: YBR088C
subclass of: SO_0000673
so part of: YBR088C
location: complement(424990..425766)
location: region:424990-425766:-1
so has part: feature:424990-425766:-1:exon

NP_009645.1
type: Protein
SIO_000068: ncbiprotein

S000000292
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:424990-425766:-1:exon

YBR089C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YBR090C-A
gene: NHP6B
locus tag: YBR089C-A
gene synonym: YBR090C-A
so part of: sequence
location: complement(<426190..>426489)
location: region:426190-426489:-1
so has part: feature:426190-426489:-1:exon
subclass of: SO_0000010

852386
type: Gene
SIO_000068: ncbigene

position:426190:-1
position: 426190
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:426489:-1
position: 426489
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:426190-426489:-1:exon

YBR089C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YBR090C-A
gene: NHP6B
locus tag: YBR089C-A
gene synonym: YBR090C-A
product: high-mobility group nucleosome-binding protein
transcript id: NM_001180058.2
SIO_010081: YBR089C-A
subclass of: SO_0000673
so part of: YBR089C-A
location: complement(<426190..>426489)
location: region:426190-426489:-1
so has part: feature:426190-426489:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:426190-426489:-1:exon

YBR089C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YBR090C-A
gene: NHP6B
locus tag: YBR089C-A
gene synonym: YBR090C-A
experiment: EXISTENCE:direct assay:GO:0001195 maintenance of transcriptional fidelity during transcription elongation by RNA polymerase III [PMID:16407207]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:3169249]
experiment: EXISTENCE:direct assay:GO:0008301 DNA binding, bending [PMID:7721780]
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:19158363]
experiment: EXISTENCE:direct assay:GO:0070898 RNA polymerase III preinitiation complex assembly [PMID:17178828]
experiment: EXISTENCE:genetic interaction:GO:0006338 chromatin remodeling [PMID:14739928]
experiment: EXISTENCE:genetic interaction:GO:0006366 transcription by RNA polymerase II [PMID:8946917]
experiment: EXISTENCE:genetic interaction:GO:0070898 RNA polymerase III preinitiation complex assembly [PMID:11287614]
note: High-mobility group (HMG) protein; binds to and remodels nucleosomes; involved in recruiting FACT and other chromatin remodelling complexes to the chromosomes; functionally redundant with Nhp6Ap; required for transcriptional initiation fidelity of some tRNA genes; homologous to mammalian HMGB1 and HMGB2; NHP6B has a paralog, NHP6A, that arose from the whole genome duplication
codon start: 1
product: high-mobility group nucleosome-binding protein
translation: MAATKEAKQPKEPKKRTTRRKKDPNAPKRGLSAYMFFANENRDIVRSENPDVTFGQVGRILGERWKALTAEEKQPYESKAQADKKRYESEKELYNATRA
SIO_010081: YBR089C-A
subclass of: SO_0000673
so part of: YBR089C-A
location: complement(426190..426489)
location: region:426190-426489:-1
so has part: feature:426190-426489:-1:exon

NP_009647.2
type: Protein
SIO_000068: ncbiprotein

S000002157
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:426190-426489:-1:exon

YBR090C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBR090C
so part of: sequence
location: complement(<426333..>427058)
location: region:426333-427058:-1
so has part: feature:426333-427058:-1:exon
subclass of: SO_0000010

852387
type: Gene
SIO_000068: ncbigene

position:426333:-1
position: 426333
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:427058:-1
position: 427058
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:426333-427058:-1:exon

YBR090C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBR090C
product: uncharacterized protein
transcript id: NM_001178438.4
SIO_010081: YBR090C
subclass of: SO_0000673
so part of: YBR090C
location: complement(join(<426333..426516,426874..>427058))
location: region:426333-427058:-1
so has part: feature:426874-427058:-1:exon
so has part: feature:426333-426516:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:426874-427058:-1:exon

position:426874:-1
position: 426874
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:426333-426516:-1:exon

position:426516:-1
position: 426516
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YBR090C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBR090C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
note: hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus
codon start: 1
product: uncharacterized protein
translation: MVPAPGSRAFPSPVFLGGVFFVFFFRWRGNYKVQQVRLRQYWEFTLWETAPNTKQKNDFFAKTLTYIKLALWPQLKKQSNQRNQRRGPPGERRILTPLRGACQLICSLLMKTETLSVPRILT
SIO_010081: YBR090C
subclass of: SO_0000673
so part of: YBR090C
location: complement(join(426333..426516,426874..427058))
location: region:426333-427058:-1
so has part: feature:426874-427058:-1:exon
so has part: feature:426333-426516:-1:exon

NP_009648.4
type: Protein
SIO_000068: ncbiprotein

S000000294
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:426874-427058:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:426333-426516:-1:exon

YBR091C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MRS5
gene: TIM12
locus tag: YBR091C
gene synonym: MRS5
so part of: sequence
location: complement(<427155..>427484)
location: region:427155-427484:-1
so has part: feature:427155-427484:-1:exon
subclass of: SO_0000010

852388
type: Gene
SIO_000068: ncbigene

position:427155:-1
position: 427155
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:427484:-1
position: 427484
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:427155-427484:-1:exon

YBR091C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MRS5
gene: TIM12
locus tag: YBR091C
gene synonym: MRS5
product: Tim12p
transcript id: NM_001178439.1
SIO_010081: YBR091C
subclass of: SO_0000673
so part of: YBR091C
location: complement(<427155..>427484)
location: region:427155-427484:-1
so has part: feature:427155-427484:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:427155-427484:-1:exon

YBR091C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MRS5
gene: TIM12
locus tag: YBR091C
gene synonym: MRS5
experiment: EXISTENCE:direct assay:GO:0005543 phospholipid binding [PMID:18387953]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0008320 protein transmembrane transporter activity [PMID:9430585|PMID:9495346]
experiment: EXISTENCE:direct assay:GO:0042721 TIM22 mitochondrial import inner membrane insertion complex [PMID:9495346]
experiment: EXISTENCE:direct assay:GO:0045039 protein insertion into mitochondrial inner membrane [PMID:9495346]
experiment: EXISTENCE:mutant phenotype:GO:0005543 phospholipid binding [PMID:18387953]
experiment: EXISTENCE:mutant phenotype:GO:0008320 protein transmembrane transporter activity [PMID:9430585|PMID:9495346]
experiment: EXISTENCE:mutant phenotype:GO:0045039 protein insertion into mitochondrial inner membrane [PMID:9430585|PMID:9495346]
note: Essential protein of the inner mitochondrial membrane; peripherally localized; component of the TIM22 complex, which is a twin-pore translocase that mediates insertion of numerous multispanning inner membrane proteins
codon start: 1
product: Tim12p
translation: MSFFLNSLRGNQEVSQEKLDVAGVQFDAMCSTFNNILSTCLEKCIPHEGFGEPDLTKGEQCCIDRCVAKMHYSNRLIGGFVQTRGFGPENQLRHYSRFVAKEIADDSKK
SIO_010081: YBR091C
subclass of: SO_0000673
so part of: YBR091C
location: complement(427155..427484)
location: region:427155-427484:-1
so has part: feature:427155-427484:-1:exon

NP_009649.1
type: Protein
SIO_000068: ncbiprotein

S000000295
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:427155-427484:-1:exon

YBR092C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PHO3
locus tag: YBR092C
so part of: sequence
location: complement(<427698..>429101)
location: region:427698-429101:-1
so has part: feature:427698-429101:-1:exon
subclass of: SO_0000010

852389
type: Gene
SIO_000068: ncbigene

position:427698:-1
position: 427698
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:429101:-1
position: 429101
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:427698-429101:-1:exon

YBR092C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PHO3
locus tag: YBR092C
product: acid phosphatase PHO3
transcript id: NM_001178440.1
SIO_010081: YBR092C
subclass of: SO_0000673
so part of: YBR092C
location: complement(<427698..>429101)
location: region:427698-429101:-1
so has part: feature:427698-429101:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:427698-429101:-1:exon

YBR092C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PHO3
locus tag: YBR092C
EC number: 3.1.3.2
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0006796 phosphate-containing compound metabolic process [PMID:2407294]
experiment: EXISTENCE:direct assay:GO:0042723 thiamine-containing compound metabolic process [PMID:2407294]
experiment: EXISTENCE:mutant phenotype:GO:0003993 acid phosphatase activity [PMID:2676709]
experiment: EXISTENCE:mutant phenotype:GO:0030287 cell wall-bounded periplasmic space [PMID:2676709]
note: Constitutively expressed acid phosphatase similar to Pho5p; brought to the cell surface by transport vesicles; hydrolyzes thiamin phosphates in the periplasmic space, increasing cellular thiamin uptake; expression is repressed by thiamin
codon start: 1
product: acid phosphatase PHO3
translation: MFKSVVYSVLAAALVNAGTIPLGELADVAKIGTQEDIFPFLGGAGPYFSFPGDYGISRDLPEGCEMKQLQMLARHGERYPTYSKGATIMKTWYKLSNYTRQFNGSLSFLNDDYEFFIRDDDDLEMETTFANSDNVLNPYTGEMDAKRHAREFLAQYGYMFENQTSFPIFAASSERVHDTAQYFIDGLGDQFNISLQTVSEAMSAGANTLSAGNACPGWDEDANDDILDKYDTTYLDDIAKRLNKENKGLNLTSKDANTLFAWCAYELNARGYSDVCDIFTEDELVRYSYGQDLVSFYQDGPGYDMIRSVGANLFNATLKLLKQSETQDLKVWLSFTHDTDILNYLTTAGIIDDKNNLTAEYVPFMGNTFHKSWYVPQGARVYTEKFQCSNDTYVRYVINDAVVPIETCSTGPGFSCEINDFYDYAEKRVAGTDFLKVCNVSSVSNVTELTFYWDWNTTHYNDTLLKQ
SIO_010081: YBR092C
subclass of: SO_0000673
so part of: YBR092C
location: complement(427698..429101)
location: region:427698-429101:-1
so has part: feature:427698-429101:-1:exon

NP_009650.1
type: Protein
SIO_000068: ncbiprotein

S000000296
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:427698-429101:-1:exon

YBR093C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PHO5
locus tag: YBR093C
so part of: sequence
location: complement(<429548..>430951)
location: region:429548-430951:-1
so has part: feature:429548-430951:-1:exon
subclass of: SO_0000010

852390
type: Gene
SIO_000068: ncbigene

position:429548:-1
position: 429548
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:430951:-1
position: 430951
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:429548-430951:-1:exon

YBR093C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PHO5
locus tag: YBR093C
product: acid phosphatase PHO5
transcript id: NM_001178441.3
SIO_010081: YBR093C
subclass of: SO_0000673
so part of: YBR093C
location: complement(<429548..>430951)
location: region:429548-430951:-1
so has part: feature:429548-430951:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:429548-430951:-1:exon

YBR093C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PHO5
locus tag: YBR093C
EC number: 3.1.3.2
experiment: EXISTENCE:direct assay:GO:0003993 acid phosphatase activity [PMID:8817921]
experiment: EXISTENCE:direct assay:GO:0009277 fungal-type cell wall [PMID:3537693]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0017111 ribonucleoside triphosphate phosphatase activity [PMID:16278456]
experiment: EXISTENCE:genetic interaction:GO:0047429 nucleoside triphosphate diphosphatase activity [PMID:16278456]
experiment: EXISTENCE:mutant phenotype:GO:0006796 phosphate-containing compound metabolic process [PMID:16278456]
experiment: EXISTENCE:mutant phenotype:GO:0008361 regulation of cell size [PMID:12089449]
experiment: EXISTENCE:mutant phenotype:GO:0016036 cellular response to phosphate starvation [PMID:16278456]
experiment: EXISTENCE:mutant phenotype:GO:0017111 ribonucleoside triphosphate phosphatase activity [PMID:16278456]
experiment: EXISTENCE:mutant phenotype:GO:0047429 nucleoside triphosphate diphosphatase activity [PMID:16278456]
note: Repressible acid phosphatase; 1 of 3 repressible acid phosphatases that also mediates extracellular nucleotide-derived phosphate hydrolysis; secretory pathway derived cell surface glycoprotein; induced by phosphate starvation and coordinately regulated by PHO4 and PHO2
codon start: 1
product: acid phosphatase PHO5
translation: MFKSVVYSILAASLANAGTIPLGKLADVDKIGTQKDIFPFLGGAGPYYSFPGDYGISRDLPEGCEMKQLQMVGRHGERYPTVSLAKTIKSTWYKLSNYTRQFNGSLSFLNDDYEFFIRDDDDLEMETTFANSDDVLNPYTGEMNAKRHARDFLAQYGYMVENQTSFAVFTSNSKRCHDTAQYFIDGLGDQFNITLQTVSEAESAGANTLSACNSCPAWDYDANDDIVNEYDTTYLDDIAKRLNKENKGLNLTSTDASTLFSWCAFEVNAKGYSDVCDIFTKDELVHYSYYQDLHTYYHEGPGYDIIKSVGSNLFNASVKLLKQSEIQDQKVWLSFTHDTDILNFLTTAGIIDDKNNLTAEYVPFMGNTFHRSWYVPQGARVYTEKFQCSNDTYVRYVINDAVVPIETCSTGPGFSCEINDFYDYAEKRVAGTDFLKVCNVSSVSNSTELTFYWDWNTTHYNASLLRQ
SIO_010081: YBR093C
subclass of: SO_0000673
so part of: YBR093C
location: complement(429548..430951)
location: region:429548-430951:-1
so has part: feature:429548-430951:-1:exon

NP_009651.3
type: Protein
SIO_000068: ncbiprotein

S000000297
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:429548-430951:-1:exon

YBR094W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PBY1
locus tag: YBR094W
so part of: sequence
location: <432036..>434297
location: region:432036-434297:1
so has part: feature:432036-434297:1:exon
subclass of: SO_0000010

852391
type: Gene
SIO_000068: ncbigene

position:432036:1
position: 432036
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:434297:1
position: 434297
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:432036-434297:1:exon

YBR094W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PBY1
locus tag: YBR094W
product: putative tubulin tyrosine ligase
transcript id: NM_001178442.2
SIO_010081: YBR094W
subclass of: SO_0000673
so part of: YBR094W
location: <432036..>434297
location: region:432036-434297:1
so has part: feature:432036-434297:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:432036-434297:1:exon

YBR094W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PBY1
locus tag: YBR094W
EC number: 6.3.2.25
experiment: EXISTENCE:direct assay:GO:0000932 P-body [PMID:17307817]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095|PMID:22842922]
note: Putative tubulin tyrosine ligase associated with P-bodies; may have a role in mRNA metabolism; yeast knockout collection strain identified as a pby1 null mutant is actually wild-type for PBY1 and deleted for mms4
codon start: 1
product: putative tubulin tyrosine ligase
translation: MRVLITNDDGPLSDQFSPYIRPFIQHIKRNYPEWKITVCVPHVQKSWVGKAHLAGKNLTAQFIYSKVDAEDNTFWGPFIQPQIRSENSKLPYVLNAEIPKDTIEWILIDGTPASCANIGLHLLSNEPFDLVLSGPNVGRNTSAAYITSSGTVGGAMESVITGNTKAIAISWAYFNGLKNVSPLLMEKASKRSLDVIKHLVKNWDPKTDLYSINIPLVESLSDDTKVYYAPIWENRWIPIFNGPHINLENSFAEIEDGNESSSISFNWAPKFGAHKDSIHYMDEYKDRTVLTDAEVIESEMISVTPMKATFKGVNHLLGELKLTEEENNLSKTNNLIVVSIDPMEYIYKPLTHALKKYLPQVEIVSNLPEFDNGGCEKEMKVFHYGDYEQLDMDKLMELPNNYFTNSYIYRKALIRKHFLSHTIQTYTAKNPESILKKAYLESFTIDLDYAEFLDDALDENWELRQELENESQDKWWIVKPSMSDKGQGIRVFKTIEDLQAIFDSFDDEDSEAEESGNDDDADDVNGEFMDNNKVNISQLRHFIIQEYLTNPLLLASMDNRKFHIRCYVVCRGDLQVFVYDRMLALFAAKPFVPLDPYAYSVTDLKDLECHLTNTCLQSKKKDKDSSVLEFDSIEEIPNERKSNIKEQIHSITNDVFLAAVNVNRLNFQPLPNAFETYGVDFLIDSNYEVKLLEINAFPDFKQTGKDLKNLIDELFDDTVKYCVTPIFNENRNKTDDETDPNFVKVIDYTSNGW
SIO_010081: YBR094W
subclass of: SO_0000673
so part of: YBR094W
location: 432036..434297
location: region:432036-434297:1
so has part: feature:432036-434297:1:exon

NP_009652.2
type: Protein
SIO_000068: ncbiprotein

S000000298
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:432036-434297:1:exon

YBR095C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RAF60
gene: RXT2
locus tag: YBR095C
gene synonym: RAF60
so part of: sequence
location: complement(<434406..>435698)
location: region:434406-435698:-1
so has part: feature:434406-435698:-1:exon
subclass of: SO_0000010

852392
type: Gene
SIO_000068: ncbigene

position:434406:-1
position: 434406
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:435698:-1
position: 435698
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:434406-435698:-1:exon

YBR095C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RAF60
gene: RXT2
locus tag: YBR095C
gene synonym: RAF60
product: Rxt2p
transcript id: NM_001178443.1
SIO_010081: YBR095C
subclass of: SO_0000673
so part of: YBR095C
location: complement(<434406..>435698)
location: region:434406-435698:-1
so has part: feature:434406-435698:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:434406-435698:-1:exon

YBR095C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RAF60
gene: RXT2
locus tag: YBR095C
gene synonym: RAF60
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22932476|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0033698 Rpd3L complex [PMID:16286007|PMID:16286008|PMID:16314178|PMID:19040720]
experiment: EXISTENCE:direct assay:GO:0070210 Rpd3L-Expanded complex [PMID:19040720]
experiment: EXISTENCE:mutant phenotype:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:16275642]
experiment: EXISTENCE:mutant phenotype:GO:0000747 conjugation with cellular fusion [PMID:10628851]
experiment: EXISTENCE:mutant phenotype:GO:0001403 invasive growth in response to glucose limitation [PMID:10628851]
experiment: EXISTENCE:mutant phenotype:GO:0004407 histone deacetylase activity [PMID:16275642]
experiment: EXISTENCE:mutant phenotype:GO:0061186 negative regulation of silent mating-type cassette heterochromatin formation [PMID:16286008]
experiment: EXISTENCE:mutant phenotype:GO:0061188 negative regulation of rDNA heterochromatin formation [PMID:16286008]
experiment: EXISTENCE:mutant phenotype:GO:2000219 positive regulation of invasive growth in response to glucose limitation [PMID:18202364]
note: Component of the histone deacetylase Rpd3L complex; possibly involved in cell fusion and invasive growth; relocalizes to the cytosol in response to hypoxia
codon start: 1
product: Rxt2p
translation: MTIRSSMKNNAELESKSVLANESNIISTFTRRIIKEKSGNYQVLKRSLDGKLIYPEATGISSNRGNKLLQRSEVVTRRDLNNSKPMIEQTVFYNGSEHRLLQTNIVTDSRRKRIKFTPDINVEPVLVGDENDIDGSEKEDENITDEYYGEEDDDDLSKLVNVKEILTPILSLGDIINHKTISRTFSSPILKNLALQIILMIEKEQMSVVRYSQFLEVFLGDHPEPIYESNLNLPSYNHNLTLPEDRGASDEDDINNKNNINEVNSNSLSTEAGHINNGMEEFGEEDPFFALPRLEQSNALLSLLPSSSGSASISTLTAAEQQQLNEEIESARQLSQIALQRNKEFIRNLQKIRKSVIKANRIRGRILNWSREYLGISDDDITIPVALRVVKRGLISATTNKTTNFEEEIENTMEDGVVDDNEPDEEANRA
SIO_010081: YBR095C
subclass of: SO_0000673
so part of: YBR095C
location: complement(434406..435698)
location: region:434406-435698:-1
so has part: feature:434406-435698:-1:exon

NP_009653.2
type: Protein
SIO_000068: ncbiprotein

S000000299
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:434406-435698:-1:exon

YBR096W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBR096W
so part of: sequence
location: <436021..>436713
location: region:436021-436713:1
so has part: feature:436021-436713:1:exon
subclass of: SO_0000010

852393
type: Gene
SIO_000068: ncbigene

position:436021:1
position: 436021
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:436713:1
position: 436713
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:436021-436713:1:exon

YBR096W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBR096W
product: uncharacterized protein
transcript id: NM_001178444.3
SIO_010081: YBR096W
subclass of: SO_0000673
so part of: YBR096W
location: <436021..>436713
location: region:436021-436713:1
so has part: feature:436021-436713:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:436021-436713:1:exon

YBR096W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBR096W
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:14562095]
note: hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to the ER
codon start: 1
product: uncharacterized protein
translation: MGVCTIFRWLFAAYLLSSYKSLPGAYFVRFYYYVIQNLFLPMFTGFETENIKKLEKNEYGCFSYTSLDTYASPFECDFYFHKSNSTYFAELDISRGNLMCKIFQKLMLNSKHYPYIPVANVFTNFLKEIKPFQKYSVSSRIICWDEKWIYVMSRFTIKKGTVLCSLSLTKYVLKDGRKTIKPKDALEYCGLYNEKVAKISEDNLKLLTERCGFHETVPLENLSQEYCSEI
SIO_010081: YBR096W
subclass of: SO_0000673
so part of: YBR096W
location: 436021..436713
location: region:436021-436713:1
so has part: feature:436021-436713:1:exon

NP_009654.3
type: Protein
SIO_000068: ncbiprotein

S000000300
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:436021-436713:1:exon

YBR097W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: GRD8
alternative label: VAC4
alternative label: VPL19
alternative label: VPS40
alternative label: VPT15
gene: VPS15
locus tag: YBR097W
gene synonym: GRD8; VAC4; VPL19; VPS40; VPT15
so part of: sequence
location: <436951..>441315
location: region:436951-441315:1
so has part: feature:436951-441315:1:exon
subclass of: SO_0000010

852394
type: Gene
SIO_000068: ncbigene

position:436951:1
position: 436951
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:441315:1
position: 441315
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:436951-441315:1:exon

YBR097W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: GRD8
alternative label: VAC4
alternative label: VPL19
alternative label: VPS40
alternative label: VPT15
gene: VPS15
locus tag: YBR097W
gene synonym: GRD8; VAC4; VPL19; VPS40; VPT15
product: ubiquitin-binding serine/threonine protein kinase VPS15
transcript id: NM_001178445.2
SIO_010081: YBR097W
subclass of: SO_0000673
so part of: YBR097W
location: <436951..>441315
location: region:436951-441315:1
so has part: feature:436951-441315:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:436951-441315:1:exon

YBR097W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: GRD8
alternative label: VAC4
alternative label: VPL19
alternative label: VPS40
alternative label: VPT15
gene: VPS15
locus tag: YBR097W
gene synonym: GRD8; VAC4; VPL19; VPS40; VPT15
EC number: 2.7.11.1
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0004674 protein serine/threonine kinase activity [PMID:7989323]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I [PMID:11157979]
experiment: EXISTENCE:direct assay:GO:0034272 phosphatidylinositol 3-kinase complex, class III, type II [PMID:11157979]
experiment: EXISTENCE:direct assay:GO:0043130 ubiquitin binding [PMID:21070969]
experiment: EXISTENCE:direct assay:GO:0071561 nucleus-vacuole junction [PMID:23335340]
experiment: EXISTENCE:direct assay:GO:0120095 vacuole-isolation membrane contact site [PMID:23549786]
experiment: EXISTENCE:mutant phenotype:GO:0000011 vacuole inheritance [PMID:1493335]
experiment: EXISTENCE:mutant phenotype:GO:0006623 protein targeting to vacuole [PMID:7721937]
experiment: EXISTENCE:mutant phenotype:GO:0016236 macroautophagy [PMID:11157979|PMID:32788210]
experiment: EXISTENCE:mutant phenotype:GO:0030242 autophagy of peroxisome [PMID:21121900]
experiment: EXISTENCE:mutant phenotype:GO:0032968 positive regulation of transcription elongation by RNA polymerase II [PMID:23335340]
experiment: EXISTENCE:mutant phenotype:GO:0045053 protein retention in Golgi apparatus [PMID:8649377]
experiment: EXISTENCE:mutant phenotype:GO:0045324 late endosome to vacuole transport [PMID:11157979]
experiment: EXISTENCE:mutant phenotype:GO:0048017 inositol lipid-mediated signaling [PMID:16839886]
note: Serine/threonine protein kinase involved in vacuolar protein sorting; functions as a membrane-associated complex with Vps34p; active form recruits Vps34p to the Golgi membrane; interacts with the GDP-bound form of Gpa1p; myristoylated; a fraction is localized, with Vps34p, to nuclear pores at nucleus-vacuole junctions and may facilitate transcription elongation for genes positioned at the nuclear periphery
codon start: 1
product: ubiquitin-binding serine/threonine protein kinase VPS15
translation: MGAQLSLVVQASPSIAIFSYIDVLEEVHYVSQLNSSRFLKTCKALDPNGEIVIKVFIKPKDQYSLRPFLQRIRAQSFKLGQLPHVLNYSKLIETNRAGYMIRQHLKNNLYDRLSLRPYLQDIELKFIAFQLLNALKDIHNLNIVHGDIKTENILVTSWNWCILTDFAAFIKPVYLPEDNPGEFLFYFDTSKRRTCYLAPERFNSKLYQDGKSNNGRLTKEMDIFSLGCVIAEIFAEGRPIFNLSQLFKYKSNSYDVNREFLMEEMNSTDLRNLVLDMIQLDPSKRLSCDELLNKYRGIFFPDYFYTFIYDYFRNLVTMTTSTPISDNTCTNSTLEDNVKLLDETTEKIYRDFSQICHCLDFPLIKDGGEIGSDPPILESYKIEIEISRFLNTNLYFPQNYHLVLQQFTKVSEKIKSVKEECALLFISYLSHSIRSIVSTATKLKNLELLAVFAQFVSDENKIDRVVPYFVCCFEDSDQDVQALSLLTLIQVLTSVRKLNQLNENIFVDYLLPRLKRLLISNRQNTNYLRIVFANCLSDLAIIINRFQEFTFAQHCNDNSMDNNTEIMESSTKYSAKLIQSVEDLTVSFLTDNDTYVKMALLQNILPLCKFFGRERTNDIILSHLITYLNDKDPALRVSLIQTISGISILLGTVTLEQYILPLLIQTITDSEELVVISVLQSLKSLFKTGLIRKKYYIDISKTTSPLLLHPNNWIRQFTLMIIIEIINKLSKAEVYCILYPIIRPFFEFDVEFNFKSMISCCKQPVSRSVYNLLCSWSVRASKSLFWKKIITNHVDSFGNNRIEFITKNYSSKNYGFNKRDTKSSSSLKGIKTSSTVYSHDNKEIPLTAEDRNWIDKFHIIGLTEKDIWKIVALRGYVIRTARVMAANPDFPYNNSNYRPLVQNSPPNLNLTNIMPRNIFFDVEFAEESTSEGQDSNLENQQIYKYDESEKDSNKLNINGSKQLSTVMDINGSLIFKNKSIATTTSNLKNVFVQLEPTSYHMHSPNHGLKDNANVKPERKVVVSNSYEGDVESIEKFLSTFKILPPLRDYKEFGPIQEIVRSPNMGNLRGKLIATLMENEPNSITSSAVSPGETPYLITGSDQGVIKIWNLKEIIVGEVYSSSLTYDCSSTVTQITMIPNFDAFAVSSKDGQIIVLKVNHYQQESEVKFLNCECIRKINLKNFGKNEYAVRMRAFVNEEKSLLVALTNLSRVIIFDIRTLERLQIIENSPRHGAVSSICIDEECCVLILGTTRGIIDIWDIRFNVLIRSWSFGDHAPITHVEVCQFYGKNSVIVVGGSSKTFLTIWNFVKGHCQYAFINSDEQPSMEHFLPIEKGLEELNFCGIRSLNALSTISVSNDKILLTDEATSSIVMFSLNELSSSKAVISPSRFSDVFIPTQVTANLTMLLRKMKRTSTHSVDDSLYHHDIINSISTCEVDETPLLVACDNSGLIGIFQ
SIO_010081: YBR097W
subclass of: SO_0000673
so part of: YBR097W
location: 436951..441315
location: region:436951-441315:1
so has part: feature:436951-441315:1:exon

NP_009655.2
type: Protein
SIO_000068: ncbiprotein

S000000301
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:436951-441315:1:exon

YBR098W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SLX2
alternative label: YBR100W
gene: MMS4
locus tag: YBR098W
gene synonym: SLX2; YBR100W
so part of: sequence
location: <441515..>443590
location: region:441515-443590:1
so has part: feature:441515-443590:1:exon
subclass of: SO_0000010

852395
type: Gene
SIO_000068: ncbigene

position:441515:1
position: 441515
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:443590:1
position: 443590
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:441515-443590:1:exon

YBR098W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SLX2
alternative label: YBR100W
gene: MMS4
locus tag: YBR098W
gene synonym: SLX2; YBR100W
product: Mms4p
transcript id: NM_001178446.1
SIO_010081: YBR098W
subclass of: SO_0000673
so part of: YBR098W
location: <441515..>443590
location: region:441515-443590:1
so has part: feature:441515-443590:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:441515-443590:1:exon

YBR098W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SLX2
alternative label: YBR100W
gene: MMS4
locus tag: YBR098W
gene synonym: SLX2; YBR100W
experiment: EXISTENCE:direct assay:GO:0004520 endodeoxyribonuclease activity [PMID:11641278]
experiment: EXISTENCE:direct assay:GO:0008821 crossover junction endodeoxyribonuclease activity [PMID:17363897]
experiment: EXISTENCE:direct assay:GO:0048476 Holliday junction resolvase complex [PMID:17363897]
experiment: EXISTENCE:genetic interaction:GO:0000712 resolution of meiotic recombination intermediates [PMID:18691964]
experiment: EXISTENCE:genetic interaction:GO:0006265 DNA topological change [PMID:11139495]
experiment: EXISTENCE:genetic interaction:GO:0007131 reciprocal meiotic recombination [PMID:11641278]
experiment: EXISTENCE:genetic interaction:GO:0010520 regulation of reciprocal meiotic recombination [PMID:18691965]
experiment: EXISTENCE:mutant phenotype:GO:0006281 DNA repair [PMID:9604884]
experiment: EXISTENCE:mutant phenotype:GO:0006974 cellular response to DNA damage stimulus [PMID:11139495]
experiment: EXISTENCE:mutant phenotype:GO:0007131 reciprocal meiotic recombination [PMID:18615017]
note: Subunit of structure-specific Mms4p-Mus81p endonuclease; cleaves branched DNA; involved in recombination, DNA repair, and joint molecule formation/resolution during meiotic recombination; phosphorylation of the non-catalytic subunit Mms4p by Cdc28p and Cdc5p during mitotic cell cycle activates the function of Mms4p-Mus81p
codon start: 1
product: Mms4p
translation: MSQIVDFVEDKDSRNDASIQIIDGPSNVEIIALSESMDQDECKRAHVSSAEMIPSSPQRKSVSNDVENVDLNKSIELSAPFFQDISISKLDDFSTTVNSIIDSSLRNENNAKGNAKKLLDDLISDEWSADLESSGKKHNKSQYNLRDIAEKWGVQSLKNPEPIAVDCEYKTQGIGKTNSDISDSPKSQIGAADILFDFPLSPVKHENPTEEKHNSIANENSSPDNSLKPAGKQNHGEDGTSMAKRVYNKGEDEQEHLPKGKKRTIALSRTLINSTKLPDTVELNLSKFLDSSDSITTDVLSTPAKGSNIVRTGSQPIFSNANCFQEAKRSKTLTAEDPKCTKNTAREVSQLENYIAYGQYYTREDSKNKIRHLLKENKNAFKRVNQIYRDNIKARSQMIIEFSPSLLQLFKKGDSDLQQQLAPAVVQSSYNDSMPLLRFLRKCDSIYDFSNDFYYPCDPKIVEENVLILYYDAQEFFEQYTSQKKELYRKIRFFSKNGKHVILILSDINKLKRAIFQLENEKYKARVEQRLSGTEEALRPRSKKSSQVGKLGIKKFDLEQRLRFIDREWHVKIHTVNSHMEFINSLPNLVSLIGKQRMDPAIRYMKYAHLNVKSAQDSTETLKKTFHQIGRMPEMKANNVVSLYPSFQSLLEDIEKGRLQSDNEGKYLMTEAVEKRLYKLFTCTDPNDTIE
SIO_010081: YBR098W
subclass of: SO_0000673
so part of: YBR098W
location: 441515..443590
location: region:441515-443590:1
so has part: feature:441515-443590:1:exon

NP_009656.2
type: Protein
SIO_000068: ncbiprotein

S000000302
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:441515-443590:1:exon

YBR101C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FES1
locus tag: YBR101C
so part of: sequence
location: complement(<443821..>444693)
location: region:443821-444693:-1
so has part: feature:443821-444693:-1:exon
subclass of: SO_0000010

852397
type: Gene
SIO_000068: ncbigene

position:443821:-1
position: 443821
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:444693:-1
position: 444693
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:443821-444693:-1:exon

YBR101C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FES1
locus tag: YBR101C
product: Hsp70 nucleotide exchange factor FES1
transcript id: NM_001178449.3
SIO_010081: YBR101C
subclass of: SO_0000673
so part of: YBR101C
location: complement(<443821..>444693)
location: region:443821-444693:-1
so has part: feature:443821-444693:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:443821-444693:-1:exon

YBR101C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FES1
locus tag: YBR101C
experiment: EXISTENCE:direct assay:GO:0000774 adenyl-nucleotide exchange factor activity [PMID:12052876]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:12052876]
experiment: EXISTENCE:direct assay:GO:0071629 cytoplasm protein quality control by the ubiquitin-proteasome system [PMID:23530227]
experiment: EXISTENCE:mutant phenotype:GO:0071629 cytoplasm protein quality control by the ubiquitin-proteasome system [PMID:23530227]
note: Hsp70 (Ssa1p) nucleotide exchange factor; required for the release of misfolded proteins from the Hsp70 system to the Ub-proteasome machinery for degradation; cytosolic homolog of Sil1p, which is the nucleotide exchange factor for BiP (Kar2p) in the endoplasmic reticulum; protein abundance increases in response to DNA replication stress
codon start: 1
product: Hsp70 nucleotide exchange factor FES1
translation: MEKLLQWSIANSQGDKEAMARAGQPDPKLLQQLFGGGGPDDPTLMKESMAVIMNPEVDLETKLVAFDNFEMLIENLDNANNIENLKLWEPLLDVLVQTKDEELRAAALSIIGTAVQNNLDSQNNFMKYDNGLRSLIEIASDKTKPLDVRTKAFYALSNLIRNHKDISEKFFKLNGLDCIAPVLSDNTAKPKLKMRAIALLTAYLSSVKIDENIISVLRKDGVIESTIECLSDESNLNIIDRVLSFLSHLISSGIKFNEQELHKLNEGYKHIEPLKDRLNEDDYLAVKYVL
SIO_010081: YBR101C
subclass of: SO_0000673
so part of: YBR101C
location: complement(443821..444693)
location: region:443821-444693:-1
so has part: feature:443821-444693:-1:exon

NP_009659.3
type: Protein
SIO_000068: ncbiprotein

S000000305
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:443821-444693:-1:exon

YBR102C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: USA3
gene: EXO84
locus tag: YBR102C
gene synonym: USA3
so part of: sequence
location: complement(<445062..>447323)
location: region:445062-447323:-1
so has part: feature:445062-447323:-1:exon
subclass of: SO_0000010

852398
type: Gene
SIO_000068: ncbigene

position:445062:-1
position: 445062
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:447323:-1
position: 447323
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:445062-447323:-1:exon

YBR102C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: USA3
gene: EXO84
locus tag: YBR102C
gene synonym: USA3
product: exocyst subunit EXO84
transcript id: NM_001178450.1
SIO_010081: YBR102C
subclass of: SO_0000673
so part of: YBR102C
location: complement(<445062..>447323)
location: region:445062-447323:-1
so has part: feature:445062-447323:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:445062-447323:-1:exon

YBR102C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: USA3
gene: EXO84
locus tag: YBR102C
gene synonym: USA3
experiment: EXISTENCE:curator inference:GO:0090522 vesicle tethering involved in exocytosis [PMID:10438536]
experiment: EXISTENCE:direct assay:GO:0000131 incipient cellular bud site [PMID:10438536]
experiment: EXISTENCE:direct assay:GO:0000145 exocyst [PMID:10438536]
experiment: EXISTENCE:direct assay:GO:0005628 prospore membrane [PMID:24390141]
experiment: EXISTENCE:direct assay:GO:0005934 cellular bud tip [PMID:10438536]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:10438536]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:19053807]
experiment: EXISTENCE:genetic interaction:GO:0006887 exocytosis [PMID:10438536]
experiment: EXISTENCE:mutant phenotype:GO:0000245 spliceosomal complex assembly [PMID:11425851]
experiment: EXISTENCE:mutant phenotype:GO:0001927 exocyst assembly [PMID:15788396]
experiment: EXISTENCE:mutant phenotype:GO:0006887 exocytosis [PMID:10438536|PMID:15788396]
experiment: EXISTENCE:mutant phenotype:GO:0006893 Golgi to plasma membrane transport [PMID:10438536|PMID:15788396]
experiment: EXISTENCE:mutant phenotype:GO:0051601 exocyst localization [PMID:15788396]
experiment: EXISTENCE:physical interaction:GO:0000245 spliceosomal complex assembly [PMID:11425851]
note: Exocyst subunit with dual roles in exocytosis and spliceosome assembly; subunit of the the exocyst complex which mediates polarized targeting and tethering of post-Golgi secretory vesicles to active sites of exocytosis at the plasma membrane (PM) prior to SNARE-mediated fusion; required for exocyst assembly and targeting the complex to specific sites on the bud tip PM; associates the U1 snRNP; role in pre-mRNA splicing and prespliceosome formation; possible Cdc28 substrate
codon start: 1
product: exocyst subunit EXO84
translation: MVEFSLKKARNNWKHVKKSASSPAKQKTPPSPAKPKQKTKKNPYSDLKDPATSYTLPTINARERSRVATSMQRRLSIHNTNYAPPTLDYSMPLPDMPNMIVPNDNVDSSHNNSSFTTENESVSSKGPSNSLNLSTADLSLNDSSYNKVPARSAMRNTVNPSGSNDPFNNSTSLRKMLANPHFNAKDFVHDKLGNASAITIDKFTSNLTDLSIQVQEEVKLNINKSYNEIMTVNNDLNVAMLELKRVRANINDLNEVLDQCTKIAEKRLQLQDQIDQERQGNFNNVESHSNSPALLPPLKAGQNGNLMRRDRSSVLILEKFWDTELDQLFKNVEGAQKFINSTKGRHILMNSANWMELNTTTGKPLQMVQIFILNDLVLIADKSRDKQNDFIVSQCYPLKDVTVTQEEFSTKRLLFKFSNSNSSLYECRDADECSRLLDVIRKAKDDLCDIFHVEEENSKRIRESFRYLQSTQQTPGRENNRSPNKNKRRSMGGSITPGRNVTGAMDQYLLQNLTLSMHSRPRSRDMSSTAQRLKFLDEGVEEIDIELARLRFESAVETLLDIESQLEDLSERISDEELMLLNLISLKIEQRREAISSKLSQSILSSNEIVHLKSGTENMIKLGLPEQALDLFLQNRSNFIQDLILQIGSVDNPTNYLTQLAVIRFQTIKKTVEDFQDIFKELGAKISSILVDWCSDEVDNHFKLIDKQLLNDEMLSPGSIKSSRKQIDGLKAVGLDFVYKLDEFIKKNSDKIR
SIO_010081: YBR102C
subclass of: SO_0000673
so part of: YBR102C
location: complement(445062..447323)
location: region:445062-447323:-1
so has part: feature:445062-447323:-1:exon

NP_009660.1
type: Protein
SIO_000068: ncbiprotein

S000000306
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:445062-447323:-1:exon

YBR103W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: EMB1
gene: SIF2
locus tag: YBR103W
gene synonym: EMB1
so part of: sequence
location: <447709..>449316
location: region:447709-449316:1
so has part: feature:447709-449316:1:exon
subclass of: SO_0000010

852399
type: Gene
SIO_000068: ncbigene

position:447709:1
position: 447709
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:449316:1
position: 449316
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:447709-449316:1:exon

YBR103W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: EMB1
gene: SIF2
locus tag: YBR103W
gene synonym: EMB1
product: Sif2p
transcript id: NM_001178451.1
SIO_010081: YBR103W
subclass of: SO_0000673
so part of: YBR103W
location: <447709..>449316
location: region:447709-449316:1
so has part: feature:447709-449316:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:447709-449316:1:exon

YBR103W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: EMB1
gene: SIF2
locus tag: YBR103W
gene synonym: EMB1
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:9651685]
experiment: EXISTENCE:direct assay:GO:0034967 Set3 complex [PMID:11711434]
experiment: EXISTENCE:direct assay:GO:0070210 Rpd3L-Expanded complex [PMID:19040720]
experiment: EXISTENCE:mutant phenotype:GO:0006355 regulation of DNA-templated transcription [PMID:19379692]
experiment: EXISTENCE:mutant phenotype:GO:0032874 positive regulation of stress-activated MAPK cascade [PMID:18487345]
experiment: EXISTENCE:physical interaction:GO:0045835 negative regulation of meiotic nuclear division [PMID:11711434]
note: WD40 repeat-containing subunit of Set3C histone deacetylase complex; complex represses early/middle sporulation genes; antagonizes telomeric silencing; binds specifically to the Sir4p N-terminus
codon start: 1
product: Sif2p
translation: MSITSEELNYLIWRYCQEMGHEVSALALQDETRVLEFDEKYKEHIPLGTLVNLVQRGILYTESELMVDSKGDISALNEHHLSEDFNLVQALQIDKEKFPEISSEGRFTLETNSESNKAGEDGASTVERETQEDDTNSIDSSDDLDGFVKILKEIVKLDNIVSSTWNPLDESILAYGEKNSVARLARIVETDQEGKKYWKLTIIAELRHPFALSASSGKTTNQVTCLAWSHDGNSIVTGVENGELRLWNKTGALLNVLNFHRAPIVSVKWNKDGTHIISMDVENVTILWNVISGTVMQHFELKETGGSSINAENHSGDGSLGVDVEWVDDDKFVIPGPKGAIFVYQITEKTPTGKLIGHHGPISVLEFNDTNKLLLSASDDGTLRIWHGGNGNSQNCFYGHSQSIVSASWVGDDKVISCSMDGSVRLWSLKQNTLLALSIVDGVPIFAGRISQDGQKYAVAFMDGQVNVYDLKKLNSKSRSLYGNRDGILNPLPIPLYASYQSSQDNDYIFDLSWNCAGNKISVAYSLQEGSVVAI
SIO_010081: YBR103W
subclass of: SO_0000673
so part of: YBR103W
location: 447709..449316
location: region:447709-449316:1
so has part: feature:447709-449316:1:exon

NP_009661.1
type: Protein
SIO_000068: ncbiprotein

S000000307
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:447709-449316:1:exon

YBR104W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: YMC2
locus tag: YBR104W
so part of: sequence
location: <449667..>450656
location: region:449667-450656:1
so has part: feature:449667-450656:1:exon
subclass of: SO_0000010

852401
type: Gene
SIO_000068: ncbigene

position:449667:1
position: 449667
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:450656:1
position: 450656
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:449667-450656:1:exon

YBR104W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: YMC2
locus tag: YBR104W
product: organic acid transporter
transcript id: NM_001178452.3
SIO_010081: YBR104W
subclass of: SO_0000673
so part of: YBR104W
location: <449667..>450656
location: region:449667-450656:1
so has part: feature:449667-450656:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:449667-450656:1:exon

YBR104W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: YMC2
locus tag: YBR104W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16140254|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:genetic interaction:GO:0005342 organic acid transmembrane transporter activity [PMID:16140254]
experiment: EXISTENCE:genetic interaction:GO:0006839 mitochondrial transport [PMID:16140254]
experiment: EXISTENCE:genetic interaction:GO:0055085 transmembrane transport [PMID:16140254]
note: Putative mitochondrial inner membrane transporter; proposed role in oleate metabolism and glutamate biosynthesis; member of the mitochondrial carrier (MCF) family; YMC2 has a paralog, YMC1, that arose from the whole genome duplication
codon start: 1
product: organic acid transporter
translation: MSEEFPTPQLLDELEDQQKVTTPNEKRELSSNRVLKDIFAGTIGGIAQVLVGQPFDTTKVRLQTATTRTTTLEVLRNLVKNEGVFAFYKGALTPLLGVGICVSVQFGVNEAMKRFFQNYNASKNPNMSSQDVDLSRSNTLPLSQYYVCGLTGGVVNSFLASPIEQIRIRLQTQTSNGGDREFKGPWDCIKKLKAQGGLMRGLFPTMIRAGHGLGTYFLVYEALVAREIGTGLTRNEIPPWKLCLFGAFSGTMLWLTVYPLDVVKSIIQNDDLRKPKYKNSISYVAKTIYAKEGIRAFFKGFGPTMVRSAPVNGATFLTFELVMRFLGEE
SIO_010081: YBR104W
subclass of: SO_0000673
so part of: YBR104W
location: 449667..450656
location: region:449667-450656:1
so has part: feature:449667-450656:1:exon

NP_009662.3
type: Protein
SIO_000068: ncbiprotein

S000000308
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:449667-450656:1:exon

YBR105C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: GID4
gene: VID24
locus tag: YBR105C
gene synonym: GID4
so part of: sequence
location: complement(<450881..>451969)
location: region:450881-451969:-1
so has part: feature:450881-451969:-1:exon
subclass of: SO_0000010

852402
type: Gene
SIO_000068: ncbigene

position:450881:-1
position: 450881
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:451969:-1
position: 451969
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:450881-451969:-1:exon

YBR105C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: GID4
gene: VID24
locus tag: YBR105C
gene synonym: GID4
product: glucose-induced degradation complex subunit VID24
transcript id: NM_001178453.1
SIO_010081: YBR105C
subclass of: SO_0000673
so part of: YBR105C
location: complement(<450881..>451969)
location: region:450881-451969:-1
so has part: feature:450881-451969:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:450881-451969:-1:exon

YBR105C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: GID4
gene: VID24
locus tag: YBR105C
gene synonym: GID4
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0031410 cytoplasmic vesicle [PMID:9508768]
experiment: EXISTENCE:direct assay:GO:0034657 GID complex [PMID:16872538|PMID:18508925]
experiment: EXISTENCE:mutant phenotype:GO:0006623 protein targeting to vacuole [PMID:9508768|PMID:12730205]
experiment: EXISTENCE:mutant phenotype:GO:0007039 protein catabolic process in the vacuole [PMID:15358789|PMID:9508768]
experiment: EXISTENCE:mutant phenotype:GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process [PMID:12686616|PMID:15358789]
experiment: EXISTENCE:mutant phenotype:GO:0045721 negative regulation of gluconeogenesis [PMID:12686616]
note: GID Complex regulatory subunit; binds GID Complex in response to glucose through interactions with complex member Vid28p; regulates fructose-1,6-bisphosphatase (FBPase) targeting to the vacuole; promotes proteasome-dependent catabolite degradation of FBPase; peripheral membrane protein located at Vid (vacuole import and degradation) vesicles
codon start: 1
product: glucose-induced degradation complex subunit VID24
translation: MINNPKVDSVAEKPKAVTSKQSEQAASPEPTPAPPVSRNQYPITFNLTSTAPFHLHDRHRYLQEQDLYKCASRDSLSSLQQLAHTPNGSTRKKYIVEDQSPYSSENPVIVTSSYNHTVCTNYLRPRMQFTGYQISGYKRYQVTVNLKTVDLPKKDCTSLSPHLSGFLSIRGLTNQHPEISTYFEAYAVNHKELGFLSSSWKDEPVLNEFKATDQTDLEHWINFPSFRQLFLMSQKNGLNSTDDNGTTNAAKKLPPQQLPTTPSADAGNISRIFSQEKQFDNYLNERFIFMKWKEKFLVPDALLMEGVDGASYDGFYYIVHDQVTGNIQGFYYHQDAEKFQQLELVPSLKNKVESSDCSFEFA
SIO_010081: YBR105C
subclass of: SO_0000673
so part of: YBR105C
location: complement(450881..451969)
location: region:450881-451969:-1
so has part: feature:450881-451969:-1:exon

NP_009663.1
type: Protein
SIO_000068: ncbiprotein

S000000309
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:450881-451969:-1:exon

YBR106W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PHO88
gene: SND3
locus tag: YBR106W
gene synonym: PHO88
so part of: sequence
location: <452658..>453224
location: region:452658-453224:1
so has part: feature:452658-453224:1:exon
subclass of: SO_0000010

852403
type: Gene
SIO_000068: ncbigene

position:452658:1
position: 452658
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:453224:1
position: 453224
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:452658-453224:1:exon

YBR106W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PHO88
gene: SND3
locus tag: YBR106W
gene synonym: PHO88
product: Snd3p
transcript id: NM_001178454.1
SIO_010081: YBR106W
subclass of: SO_0000673
so part of: YBR106W
location: <452658..>453224
location: region:452658-453224:1
so has part: feature:452658-453224:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:452658-453224:1:exon

YBR106W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PHO88
gene: SND3
locus tag: YBR106W
gene synonym: PHO88
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:27905431|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0016020 membrane [PMID:8709965]
experiment: EXISTENCE:mutant phenotype:GO:0045047 protein targeting to ER [PMID:27905431]
experiment: EXISTENCE:mutant phenotype:GO:0051604 protein maturation [PMID:19433630]
note: Involved in SRP-independent protein targeting to the ER; component of an alternative ER-targeting pathway partially redundant with the GET pathway that can compensate for SRP loss; preference for substrates with downstream transmembrane domains; interacts with Snd1p, Env10p/Snd2p, and Sec61p-translocon subunits; role in establishing nucleus-vacuole junctions (NVJs) in high glucose; targeted to the NVJ during glucose starvation to facilitate expansion; role in phosphate transport with Pho86p
codon start: 1
product: Snd3p
translation: MNPQVSNIIIMLVMMQLSRRIDMEDPTIIMYIRILYCSSIGISWIIYQMARKRIVAKNDMTTMKYVEPGNAMSGEGEKLQVTTVRDYDLKEIDSAIKSIYTGMAMMGFMHLYLKYTNPLFMQSISPVKSALEHNEVKIHLFGKPATGDLKRPFKAPSLFGGMGQTGPKTDKKSIEEAERAGNAGVKAE
SIO_010081: YBR106W
subclass of: SO_0000673
so part of: YBR106W
location: 452658..453224
location: region:452658-453224:1
so has part: feature:452658-453224:1:exon

NP_009664.1
type: Protein
SIO_000068: ncbiprotein

S000000310
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:452658-453224:1:exon

YBR107C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MCM19
gene: IML3
locus tag: YBR107C
gene synonym: MCM19
so part of: sequence
location: complement(<453793..>454530)
location: region:453793-454530:-1
so has part: feature:453793-454530:-1:exon
subclass of: SO_0000010

852404
type: Gene
SIO_000068: ncbigene

position:453793:-1
position: 453793
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:454530:-1
position: 454530
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:453793-454530:-1:exon

YBR107C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MCM19
gene: IML3
locus tag: YBR107C
gene synonym: MCM19
product: Iml3p
transcript id: NM_001178455.3
SIO_010081: YBR107C
subclass of: SO_0000673
so part of: YBR107C
location: complement(<453793..>454530)
location: region:453793-454530:-1
so has part: feature:453793-454530:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:453793-454530:-1:exon

YBR107C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MCM19
gene: IML3
locus tag: YBR107C
gene synonym: MCM19
experiment: EXISTENCE:direct assay:GO:0000940 outer kinetochore [PMID:12589047]
experiment: EXISTENCE:genetic interaction:GO:0034087 establishment of mitotic sister chromatid cohesion [PMID:19730685]
experiment: EXISTENCE:mutant phenotype:GO:0030437 ascospore formation [PMID:15241623]
experiment: EXISTENCE:mutant phenotype:GO:0034087 establishment of mitotic sister chromatid cohesion [PMID:19730685]
experiment: EXISTENCE:mutant phenotype:GO:0034089 establishment of meiotic sister chromatid cohesion [PMID:19730685]
experiment: EXISTENCE:mutant phenotype:GO:0034090 maintenance of meiotic sister chromatid cohesion [PMID:14752166]
experiment: EXISTENCE:mutant phenotype:GO:0045144 meiotic sister chromatid segregation [PMID:15241623]
experiment: EXISTENCE:mutant phenotype:GO:0071459 protein localization to chromosome, centromeric region [PMID:16357219|PMID:26653857]
note: Outer kinetochore protein and component of the Ctf19 complex; involved in the establishment of pericentromeric cohesion during mitosis; prevents non-disjunction of sister chromatids during meiosis II; forms a stable complex with Chl4p; required for localization of Sgo1p to pericentric sites during meiosis I; orthologous to human centromere constitutive-associated network (CCAN) subunit CENP-L and fission yeast fta1
codon start: 1
product: Iml3p
translation: MPYTWKFLGISKQLSLENGIAKLNQLLNLEVDLDIQTIRVPSDPDGGTAADEYIRYEMRLDISNLDEGTYSKFIFLGNSKMEVPMFLCYCGTDNRNEVVLQWLKAEYGVIMWPIKFEQKTMIKLADASIVHVTKENIEQITWFSSKLYFEPETQDKNLRQFSIEIPRESCEGLALGYGNTMHPYNDAIVPYIYNETGMAVERLPLTSVILAGHTKIMRESIVTSTRSLRNRVLAVVLQSIQFTSE
SIO_010081: YBR107C
subclass of: SO_0000673
so part of: YBR107C
location: complement(453793..454530)
location: region:453793-454530:-1
so has part: feature:453793-454530:-1:exon

NP_009665.3
type: Protein
SIO_000068: ncbiprotein

S000000311
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:453793-454530:-1:exon

YBR108W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: AIM3
locus tag: YBR108W
so part of: sequence
location: <454822..>457665
location: region:454822-457665:1
so has part: feature:454822-457665:1:exon
subclass of: SO_0000010

852405
type: Gene
SIO_000068: ncbigene

position:454822:1
position: 454822
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:457665:1
position: 457665
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:454822-457665:1:exon

YBR108W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: AIM3
locus tag: YBR108W
product: Aim3p
transcript id: NM_001178456.2
SIO_010081: YBR108W
subclass of: SO_0000673
so part of: YBR108W
location: <454822..>457665
location: region:454822-457665:1
so has part: feature:454822-457665:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:454822-457665:1:exon

YBR108W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: AIM3
locus tag: YBR108W
experiment: EXISTENCE:direct assay:GO:0030479 actin cortical patch [PMID:21035341]
experiment: EXISTENCE:direct assay:GO:0045121 membrane raft [PMID:15561700]
experiment: EXISTENCE:genetic interaction:GO:0000147 actin cortical patch assembly [PMID:21035341]
experiment: EXISTENCE:mutant phenotype:GO:0051016 barbed-end actin filament capping [PMID:23333351]
note: Protein that inhibits barbed-end actin filament elongation; interacts with Rvs167p; null mutant is viable and displays elevated frequency of mitochondrial genome loss
codon start: 1
product: Aim3p
translation: MGFWENNKDSITSGLKSAGKYGYQGTKYVAKTGYKASKKHYNNSKARRERKSGKKNSSDEEYDSEDEMEYERKPTDIRSLKDPKSFPPPPLKPGQKTYTGQQQQQMPNGQASYAFQGAYQGQPGAGSTEQSQYAQPQYNQYPQQQLQQGVMPQQQQLQQGVVPQQPPIYGEQVPPYGSNSNATSYQSLPQQNQPQNAIPSQVSLNSASQQSTGFVSQNLQYGTQSSNPAPSPSFQNGLQCHQQPQYVSHGSTNLGQSQFPSGQQQQPTTQFGQQVLPSPAQPQQQQQGQPLPPPRGQVILPAPGEPLSNGFGQQQQQQQQQQQPLNQNNALLPQMNVEGVSGMAAVQPVYGQAMSSTTNMQDSNPSYGASPMQGQPPVGGQPPVPVRMQPQPPQPMQQGNIYPIEPSLDSTGSTPHFEVTPFDPDAPAPKPKIDIPTVDVSSLPPPPTHRDRGAVVHQEPAPSGKIQPNTTSSAASLPAKHSRTTTADNERNSGNKENDESTSKSSILGHYDVDVNIMPPPKPFRHGLDSVPSEHTTKNAPERAVPILPPRNNVEPPPPPSRGNFERTESVLSTNAANVQEDPISNFLPPPKPFRHTETKQNQNSKASPVEMKGEVLPGHPSEEDRNVEPSLVPQSKPQSQSQFRRAHMETQPIQNFQPPPKPFRRSQSSNSSDSSYTIDGPEANHGRGRGRIAKHHDGDEYNPKSENSTENGRLGDAPNSFIRKRAPTPPAPSRSEKLHEGTITSEVDSSKDANKYEKSIPPVTSSIQAQQSTKKAPPPVVKPKPRNFSLKANEYPKELTREATGQDEVLNSITNELSHIKLRKTNVNLEKLGGSKKVKDSSPVPSDLDEKYVSASGSITPPRPPPSRSSPKKVPPVVPKKNDNLKKKPPVVPKKKPLLKSLEPRPIEMERAYSGDISAADDNLNPFERYKRNVVPQEDDRLHKLK
SIO_010081: YBR108W
subclass of: SO_0000673
so part of: YBR108W
location: 454822..457665
location: region:454822-457665:1
so has part: feature:454822-457665:1:exon

NP_009666.3
type: Protein
SIO_000068: ncbiprotein

S000000312
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:454822-457665:1:exon

YBR109C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CMD1
locus tag: YBR109C
so part of: sequence
location: complement(<457919..>458362)
location: region:457919-458362:-1
so has part: feature:457919-458362:-1:exon
subclass of: SO_0000010

852406
type: Gene
SIO_000068: ncbigene

position:457919:-1
position: 457919
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:458362:-1
position: 458362
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:457919-458362:-1:exon

YBR109C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CMD1
locus tag: YBR109C
product: calmodulin
transcript id: NM_001178457.1
SIO_010081: YBR109C
subclass of: SO_0000673
so part of: YBR109C
location: complement(<457919..>458362)
location: region:457919-458362:-1
so has part: feature:457919-458362:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:457919-458362:-1:exon

YBR109C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CMD1
locus tag: YBR109C
experiment: EXISTENCE:direct assay:GO:0000131 incipient cellular bud site [PMID:1639847]
experiment: EXISTENCE:direct assay:GO:0005509 calcium ion binding [PMID:3533275|PMID:8461293]
experiment: EXISTENCE:direct assay:GO:0005823 central plaque of spindle pole body [PMID:8601600|PMID:8886974]
experiment: EXISTENCE:direct assay:GO:0005933 cellular bud [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005934 cellular bud tip [PMID:1639847]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:1639847|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0042144 vacuole fusion, non-autophagic [PMID:9859992]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:1639847]
experiment: EXISTENCE:direct assay:GO:0048306 calcium-dependent protein binding [PMID:1321337]
experiment: EXISTENCE:direct assay:GO:1903525 regulation of membrane tubulation [PMID:27093085]
experiment: EXISTENCE:genetic interaction:GO:0000742 karyogamy involved in conjugation with cellular fusion [PMID:12836012]
experiment: EXISTENCE:genetic interaction:GO:0006661 phosphatidylinositol biosynthetic process [PMID:12079494]
experiment: EXISTENCE:mutant phenotype:GO:0000742 karyogamy involved in conjugation with cellular fusion [PMID:12836012]
experiment: EXISTENCE:mutant phenotype:GO:0006606 protein import into nucleus [PMID:17878171]
experiment: EXISTENCE:mutant phenotype:GO:0006661 phosphatidylinositol biosynthetic process [PMID:12079494]
experiment: EXISTENCE:mutant phenotype:GO:0006897 endocytosis [PMID:27093085]
experiment: EXISTENCE:mutant phenotype:GO:0006898 receptor-mediated endocytosis [PMID:7988551|PMID:9450989]
experiment: EXISTENCE:mutant phenotype:GO:0007010 cytoskeleton organization [PMID:8310294]
experiment: EXISTENCE:mutant phenotype:GO:0007114 cell budding [PMID:8310294]
experiment: EXISTENCE:mutant phenotype:GO:0016237 lysosomal microautophagy [PMID:16055436]
experiment: EXISTENCE:mutant phenotype:GO:0042144 vacuole fusion, non-autophagic [PMID:9859992]
experiment: EXISTENCE:mutant phenotype:GO:0051300 spindle pole body organization [PMID:1469052]
experiment: EXISTENCE:physical interaction:GO:0005515 protein binding [PMID:10749918|PMID:8294515|PMID:9450989|PMID:9950677]
experiment: EXISTENCE:physical interaction:GO:0048306 calcium-dependent protein binding [PMID:9756868]
experiment: EXISTENCE:physical interaction:GO:0051019 mitogen-activated protein kinase binding [PMID:27421986]
note: Calmodulin; Ca2+ binding protein that regulates Ca2+ independent processes (mitosis, bud growth, actin organization, endocytosis, etc.) and Ca2+ dependent processes (stress-activated pathways), targets include Nuf1p, Myo2p and calcineurin; binds to the Hog1p MAPK in response to hyperosmotic stress; potentiates membrane tubulation and constriction mediated by the Rvs161p-Rvs167p complex; human CALM1 or CALM2 functionally complement repression induced inviability
codon start: 1
product: calmodulin
translation: MSSNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLTDAEVDDMLREVSDGSGEINIQQFAALLSK
SIO_010081: YBR109C
subclass of: SO_0000673
so part of: YBR109C
location: complement(457919..458362)
location: region:457919-458362:-1
so has part: feature:457919-458362:-1:exon

NP_009667.1
type: Protein
SIO_000068: ncbiprotein

S000000313
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:457919-458362:-1:exon

YBR110W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ALG1
locus tag: YBR110W
so part of: sequence
location: <458872..>460221
location: region:458872-460221:1
so has part: feature:458872-460221:1:exon
subclass of: SO_0000010

852407
type: Gene
SIO_000068: ncbigene

position:458872:1
position: 458872
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:460221:1
position: 460221
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:458872-460221:1:exon

YBR110W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ALG1
locus tag: YBR110W
product: chitobiosyldiphosphodolichol beta-1,4 mannosyltransferase
transcript id: NM_001178458.3
SIO_010081: YBR110W
subclass of: SO_0000673
so part of: YBR110W
location: <458872..>460221
location: region:458872-460221:1
so has part: feature:458872-460221:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:458872-460221:1:exon

YBR110W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ALG1
locus tag: YBR110W
EC number: 2.4.1.142
experiment: EXISTENCE:direct assay:GO:0019187 beta-1,4-mannosyltransferase activity [PMID:6368538]
experiment: EXISTENCE:mutant phenotype:GO:0006487 protein N-linked glycosylation [PMID:6369318]
experiment: EXISTENCE:mutant phenotype:GO:0006490 oligosaccharide-lipid intermediate biosynthetic process [PMID:7037780]
experiment: EXISTENCE:physical interaction:GO:0005783 endoplasmic reticulum [PMID:15044395]
note: Mannosyltransferase; involved in asparagine-linked glycosylation in the endoplasmic reticulum (ER); essential for viability; human homolog ALG1 complements yeast null mutant
codon start: 1
product: chitobiosyldiphosphodolichol beta-1,4 mannosyltransferase
translation: MFLEIPRWLLALIILYLSIPLVVYYVIPYLFYGNKSTKKRIIIFVLGDVGHSPRICYHAISFSKLGWQVELCGYVEDTLPKIISSDPNITVHHMSNLKRKGGGTSVIFMVKKVLFQVLSIFKLLWELRGSDYILVQNPPSIPILPIAVLYKLTGCKLIIDWHNLAYSILQLKFKGNFYHPLVLISYMVEMIFSKFADYNLTVTEAMRKYLIQSFHLNPKRCAVLYDRPASQFQPLAGDISRQKALTTKAFIKNYIRDDFDTEKGDKIIVTSTSFTPDEDIGILLGALKIYENSYVKFDSSLPKILCFITGKGPLKEKYMKQVEEYDWKRCQIEFVWLSAEDYPKLLQLCDYGVSLHTSSSGLDLPMKILDMFGSGLPVIAMNYPVLDELVQHNVNGLKFVDRRELHESLIFAMKDADLYQKLKKNVTQEAENRWQSNWERTMRDLKLIH
SIO_010081: YBR110W
subclass of: SO_0000673
so part of: YBR110W
location: 458872..460221
location: region:458872-460221:1
so has part: feature:458872-460221:1:exon

NP_009668.3
type: Protein
SIO_000068: ncbiprotein

S000000314
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:458872-460221:1:exon

YBR111C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RMA2
gene: YSA1
locus tag: YBR111C
gene synonym: RMA2
so part of: sequence
location: complement(<461178..>461873)
location: region:461178-461873:-1
so has part: feature:461178-461873:-1:exon
subclass of: SO_0000010

852408
type: Gene
SIO_000068: ncbigene

position:461178:-1
position: 461178
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:461873:-1
position: 461873
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:461178-461873:-1:exon

YBR111C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RMA2
gene: YSA1
locus tag: YBR111C
gene synonym: RMA2
product: ADP-ribose diphosphatase
transcript id: NM_001178459.1
SIO_010081: YBR111C
subclass of: SO_0000673
so part of: YBR111C
location: complement(<461178..>461873)
location: region:461178-461873:-1
so has part: feature:461178-461873:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:461178-461873:-1:exon

YBR111C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RMA2
gene: YSA1
locus tag: YBR111C
gene synonym: RMA2
EC number: 3.6.1.13
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:19251690|PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0019693 ribose phosphate metabolic process [PMID:10542272|PMID:12370179]
experiment: EXISTENCE:direct assay:GO:0047631 ADP-ribose diphosphatase activity [PMID:10542272]
note: Nudix hydrolase family member with ADP-ribose pyrophosphatase activity; shown to metabolize O-acetyl-ADP-ribose to AMP and acetylated ribose 5'-phosphate
codon start: 1
product: ADP-ribose diphosphatase
translation: MFLRNVRVISLNSRRLFRTMSTVKGKPEDAKIIEARHVKETSDCKWIGLQKIIYKDPNGKEREWDSAVRTTRSSGGVDGIGILTILKYKDGKPDEILLQKQFRPPVEGVCIEMPAGLIDAGEDIDTAALRELKEETGYSGKIISKSPTVFNDPGFTNTNLCLVTVEVDMSLPENQKPVTQLEDNEFIECFSVELHKFPDEMVKLDQQGYKLDARVQNVAQGILMAKQYHIK
SIO_010081: YBR111C
subclass of: SO_0000673
so part of: YBR111C
location: complement(461178..461873)
location: region:461178-461873:-1
so has part: feature:461178-461873:-1:exon

NP_009669.1
type: Protein
SIO_000068: ncbiprotein

S000000315
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:461178-461873:-1:exon

YBR111W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SUS1
locus tag: YBR111W-A
so part of: sequence
location: <462139..>462579
location: region:462139-462579:1
so has part: feature:462139-462579:1:exon
subclass of: SO_0000010

1466445
type: Gene
SIO_000068: ncbigene

position:462139:1
position: 462139
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:462579:1
position: 462579
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:462139-462579:1:exon

YBR111W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SUS1
locus tag: YBR111W-A
product: Sus1p
transcript id: NM_001184520.1
SIO_010081: YBR111W-A
subclass of: SO_0000673
so part of: YBR111W-A
location: join(<462139..462209,462290..462429,462500..>462579)
location: region:462139-462579:1
so has part: feature:462139-462209:1:exon
so has part: feature:462290-462429:1:exon
so has part: feature:462500-462579:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:462139-462209:1:exon

position:462209:1
position: 462209
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:462290-462429:1:exon

position:462290:1
position: 462290
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:462429:1
position: 462429
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 3
SIO_000628: feature:462500-462579:1:exon

position:462500:1
position: 462500
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YBR111W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SUS1
locus tag: YBR111W-A
experiment: EXISTENCE:direct assay:GO:0000124 SAGA complex [PMID:14718168]
experiment: EXISTENCE:direct assay:GO:0003682 chromatin binding [PMID:29598828]
experiment: EXISTENCE:direct assay:GO:0005643 nuclear pore [PMID:14718168]
experiment: EXISTENCE:direct assay:GO:0005654 nucleoplasm [PMID:14718168]
experiment: EXISTENCE:direct assay:GO:0008047 enzyme activator activity [PMID:18488019]
experiment: EXISTENCE:direct assay:GO:0070390 transcription export complex 2 [PMID:15311284]
experiment: EXISTENCE:direct assay:GO:0071819 DUBm complex [PMID:20395473]
experiment: EXISTENCE:mutant phenotype:GO:0000973 post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery [PMID:18003937]
experiment: EXISTENCE:mutant phenotype:GO:0006368 transcription elongation by RNA polymerase II promoter [PMID:18667528]
experiment: EXISTENCE:mutant phenotype:GO:0016973 poly(A)+ mRNA export from nucleus [PMID:14718168]
experiment: EXISTENCE:mutant phenotype:GO:0032880 regulation of protein localization [PMID:19269973]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:14718168]
experiment: EXISTENCE:mutant phenotype:GO:0071028 nuclear mRNA surveillance [PMID:18003937]
note: Global transcriptional regulator, component of SAGA, TREX-2 complexes; interacts with RNA polymerase II; involved in mRNA export coupled transcription activation and elongation; involved in post-transcriptional tethering of active genes to nuclear periphery and to non-nascent mRNP; plays role in negatively regulating telomere length through modulation of H2BK123 mono-ubiquitination and its interaction with nuclear pore complex
codon start: 1
product: Sus1p
translation: MTMDTAQLKSQIQQYLVESGNYELISNELKARLLQEGWVDKVKDLTKSEMNINESTNFTQILSTVEPKALEMVSDSTRETVLKQIREFLEEIVDTQ
SIO_010081: YBR111W-A
subclass of: SO_0000673
so part of: YBR111W-A
location: join(462139..462209,462290..462429,462500..462579)
location: region:462139-462579:1
so has part: feature:462139-462209:1:exon
so has part: feature:462290-462429:1:exon
so has part: feature:462500-462579:1:exon

NP_878049.2
type: Protein
SIO_000068: ncbiprotein

S000028510
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:462139-462209:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:462290-462429:1:exon

urn:…
SIO_000300: 3
SIO_000628: feature:462500-462579:1:exon

YBR112C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CRT8
alternative label: SSN6
gene: CYC8
locus tag: YBR112C
gene synonym: CRT8; SSN6
so part of: sequence
location: complement(<462870..>465770)
location: region:462870-465770:-1
so has part: feature:462870-465770:-1:exon
subclass of: SO_0000010

852410
type: Gene
SIO_000068: ncbigene

position:462870:-1
position: 462870
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:465770:-1
position: 465770
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:462870-465770:-1:exon

YBR112C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CRT8
alternative label: SSN6
gene: CYC8
locus tag: YBR112C
gene synonym: CRT8; SSN6
product: transcription regulator CYC8
transcript id: NM_001178460.3
SIO_010081: YBR112C
subclass of: SO_0000673
so part of: YBR112C
location: complement(<462870..>465770)
location: region:462870-465770:-1
so has part: feature:462870-465770:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:462870-465770:-1:exon

YBR112C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CRT8
alternative label: SSN6
gene: CYC8
locus tag: YBR112C
gene synonym: CRT8; SSN6
experiment: EXISTENCE:direct assay:GO:0003713 transcription coactivator activity [PMID:9867831]
experiment: EXISTENCE:direct assay:GO:0003714 transcription corepressor activity [PMID:9741624]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:1739976]
experiment: EXISTENCE:direct assay:GO:0042826 histone deacetylase binding [PMID:14525981]
experiment: EXISTENCE:direct assay:GO:1900191 negative regulation of single-species biofilm formation [PMID:32054862]
experiment: EXISTENCE:genetic interaction:GO:0003713 transcription coactivator activity [PMID:9867831]
experiment: EXISTENCE:genetic interaction:GO:0006338 chromatin remodeling [PMID:14739928]
experiment: EXISTENCE:mutant phenotype:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:18708352|PMID:9858577|PMID:9560430]
experiment: EXISTENCE:mutant phenotype:GO:0006357 regulation of transcription by RNA polymerase II [PMID:9280286]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:26546823]
experiment: EXISTENCE:mutant phenotype:GO:2001020 regulation of response to DNA damage stimulus [PMID:9741624]
experiment: EXISTENCE:physical interaction:GO:0003713 transcription coactivator activity [PMID:9867831]
experiment: EXISTENCE:physical interaction:GO:0003714 transcription corepressor activity [PMID:9741624]
experiment: EXISTENCE:physical interaction:GO:0017053 transcription repressor complex [PMID:9111019]
note: General transcriptional co-repressor; acts together with Tup1p; also acts as part of a transcriptional co-activator complex that recruits the SWI/SNF and SAGA complexes to promoters; can form the prion [OCT+]
codon start: 1
product: transcription regulator CYC8
translation: MNPGGEQTIMEQPAQQQQQQQQQQQQQQQQAAVPQQPLDPLTQSTAETWLSIASLAETLGDGDRAAMAYDATLQFNPSSAKALTSLAHLYRSRDMFQRAAELYERALLVNPELSDVWATLGHCYLMLDDLQRAYNAYQQALYHLSNPNVPKLWHGIGILYDRYGSLDYAEEAFAKVLELDPHFEKANEIYFRLGIIYKHQGKWSQALECFRYILPQPPAPLQEWDIWFQLGSVLESMGEWQGAKEAYEHVLAQNQHHAKVLQQLGCLYGMSNVQFYDPQKALDYLLKSLEADPSDATTWYHLGRVHMIRTDYTAAYDAFQQAVNRDSRNPIFWCSIGVLYYQISQYRDALDAYTRAIRLNPYISEVWYDLGTLYETCNNQLSDALDAYKQAARLDVNNVHIRERLEALTKQLENPGNINKSNGAPTNASPAPPPVILQPTLQPNDQGNPLNTRISAQSANATASMVQQQHPAQQTPINSSATMYSNGASPQLQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAHAQAQAQAQAQAQAQAQAQAQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLQPLPRQQLQQKGVSVQMLNPQQGQPYITQPTVIQAHQLQPFSTQAMEHPQSSQLPPQQQQLQSVQHPQQLQGQPQAQAPQPLIQHNVEQNVLPQKRYMEGAIHTLVDAAVSSSTHTENNTKSPRQPTHAIPTQAPATGITNAEPQVKKQKLNSPNSNINKLVNTATSIEENAKSEVSNQSPAVVESNTNNTSQEEKPVKANSIPSVIGAQEPPQEASPAEEATKAASVSPSTKPLNTEPESSSVQPTVSSESSTTKANDQSTAETIELSTATVPAEASPVEDEVRQHSKEENGTTEASAPSTEEAEPAASRDAEKQQDETAATTITVIKPTLETMETVKEEAKMREEEQTSQEKSPQENTLPRENVVRQVEEDENYDD
SIO_010081: YBR112C
subclass of: SO_0000673
so part of: YBR112C
location: complement(462870..465770)
location: region:462870-465770:-1
so has part: feature:462870-465770:-1:exon

NP_009670.3
type: Protein
SIO_000068: ncbiprotein

S000000316
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:462870-465770:-1:exon

YBR114W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PSO5
gene: RAD16
locus tag: YBR114W
gene synonym: PSO5
so part of: sequence
location: <467248..>469620
location: region:467248-469620:1
so has part: feature:467248-469620:1:exon
subclass of: SO_0000010

852411
type: Gene
SIO_000068: ncbigene

position:467248:1
position: 467248
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:469620:1
position: 469620
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:467248-469620:1:exon

YBR114W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PSO5
gene: RAD16
locus tag: YBR114W
gene synonym: PSO5
product: DNA repair protein RAD16
transcript id: NM_001178462.1
SIO_010081: YBR114W
subclass of: SO_0000673
so part of: YBR114W
location: <467248..>469620
location: region:467248-469620:1
so has part: feature:467248-469620:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:467248-469620:1:exon

YBR114W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PSO5
gene: RAD16
locus tag: YBR114W
gene synonym: PSO5
experiment: EXISTENCE:direct assay:GO:0000113 nucleotide-excision repair factor 4 complex [PMID:9497356]
experiment: EXISTENCE:direct assay:GO:0000715 nucleotide-excision repair, DNA damage recognition [PMID:15177043]
experiment: EXISTENCE:direct assay:GO:0003684 damaged DNA binding [PMID:9497356]
experiment: EXISTENCE:direct assay:GO:0004842 ubiquitin-protein transferase activity [PMID:16675952]
experiment: EXISTENCE:direct assay:GO:0008094 ATP-dependent activity, acting on DNA [PMID:9497356]
experiment: EXISTENCE:direct assay:GO:0008104 protein localization [PMID:15226437]
experiment: EXISTENCE:direct assay:GO:0031463 Cul3-RING ubiquitin ligase complex [PMID:16675952]
experiment: EXISTENCE:mutant phenotype:GO:0000715 nucleotide-excision repair, DNA damage recognition [PMID:15177043]
experiment: EXISTENCE:mutant phenotype:GO:0006511 ubiquitin-dependent protein catabolic process [PMID:16675952]
note: Nucleotide excision repair (NER) protein; binds damaged DNA during NER; binds DNA in an ATP-dependent manner (with Rad7p) during NER; required for NER of non-transcribed chromatin; subunit of Nucleotide Excision Repair Factor 4 (NEF4) and the Elongin-Cullin-Socs (ECS) ligase complex
codon start: 1
product: DNA repair protein RAD16
translation: MQEGGFIRRRRTRSTKKSVNYNELSDDDTAVKNSKTLQLKGNSENVNDSQDEEYRDDATLVKSPDDDDKDFIIDLTGSDKERTATDENTHAIKNDNDEIIEIKEERDVSDDDEPLTKKRKTTARKKKKKTSTKKKSPKVTPYERNTLRLYEHHPELRNVFTDLKNAPPYVPQRSKQPDGMTIKLLPFQLEGLHWLISQEESIYAGGVLADEMGMGKTIQTIALLMNDLTKSPSLVVAPTVALMQWKNEIEQHTKGQLKIYIYHGASRTTDIKDLQGYDVVLTTYAVLESVFRKQNYGFRRKNGLFKQPSVLHNIDFYRVILDEAHNIKDRQSNTARAVNNLKTQKRWCLSGTPLQNRIGEMYSLIRFLNINPFTKYFCTKCDCASKDWKFTDRMHCDHCSHVIMQHTNFFNHFMLKNIQKFGVEGPGLESFNNIQTLLKNIMLRRTKVERADDLGLPPRIVTVRRDFFNEEEKDLYRSLYTDSKRKYNSFVEEGVVLNNYANIFTLITRMRQLADHPDLVLKRLNNFPGDDIGVVICQLCNDEAEEPIESKCHHKFCRLCIKEYVESFMENNNKLTCPVCHIGLSIDLSQPALEVDLDSFKKQSIVSRLNMSGKWQSSTKIEALVEELYKLRSNKRTIKSIVFSQFTSMLDLVEWRLKRAGFQTVKLQGSMSPTQRDETIKYFMNNIQCEVFLVSLKAGGVALNLCEASQVFILDPWWNPSVEWQSGDRVHRIGQYRPVKITRFCIEDSIEARIIELQEKKANMIHATINQDEAAISRLTPADLQFLFNN
SIO_010081: YBR114W
subclass of: SO_0000673
so part of: YBR114W
location: 467248..469620
location: region:467248-469620:1
so has part: feature:467248-469620:1:exon

NP_009672.1
type: Protein
SIO_000068: ncbiprotein

S000000318
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:467248-469620:1:exon

YBR115C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: LYS2
locus tag: YBR115C
so part of: sequence
location: complement(<469748..>473926)
location: region:469748-473926:-1
so has part: feature:469748-473926:-1:exon
subclass of: SO_0000010

852412
type: Gene
SIO_000068: ncbigene

position:469748:-1
position: 469748
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:473926:-1
position: 473926
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:469748-473926:-1:exon

YBR115C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: LYS2
locus tag: YBR115C
product: L-aminoadipate-semialdehyde dehydrogenase
transcript id: NM_001178463.1
SIO_010081: YBR115C
subclass of: SO_0000673
so part of: YBR115C
location: complement(<469748..>473926)
location: region:469748-473926:-1
so has part: feature:469748-473926:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:469748-473926:-1:exon

YBR115C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: LYS2
locus tag: YBR115C
EC number: 1.2.1.31
EC number: 1.2.1.95
experiment: EXISTENCE:direct assay:GO:0004043 L-aminoadipate-semialdehyde dehydrogenase activity [PMID:10320345]
experiment: EXISTENCE:direct assay:GO:0019878 lysine biosynthetic process via aminoadipic acid [PMID:10320345]
experiment: EXISTENCE:mutant phenotype:GO:0004043 L-aminoadipate-semialdehyde dehydrogenase activity [PMID:3023949|PMID:4401608]
experiment: EXISTENCE:mutant phenotype:GO:0019878 lysine biosynthetic process via aminoadipic acid [PMID:3023949|PMID:4401608]
note: Alpha aminoadipate reductase; catalyzes the reduction of alpha-aminoadipate to alpha-aminoadipate 6-semialdehyde, which is the fifth step in biosynthesis of lysine; activation requires posttranslational phosphopantetheinylation by Lys5p
codon start: 1
product: L-aminoadipate-semialdehyde dehydrogenase
translation: MTNEKVWIEKLDNPTLSVLPHDFLRPQQEPYTKQATYSLQLPQLDVPHDSFSNKYAVALSVWAALIYRVTGDDDIVLYIANNKILRFNIQPTWSFNELYSTINNELNKLNSIEANFSFDELAEKIQSCQDLERTPQLFRLAFLENQDFKLDEFKHHLVDFALNLDTSNNAHVLNLIYNSLLYSNERVTIVADQFTQYLTAALSDPSNCITKISLITASSKDSLPDPTKNLGWCDFVGCIHDIFQDNAEAFPERTCVVETPTLNSDKSRSFTYRDINRTSNIVAHYLIKTGIKRGDVVMIYSSRGVDLMVCVMGVLKAGATFSVIDPAYPPARQTIYLGVAKPRGLIVIRAAGQLDQLVEDYINDELEIVSRINSIAIQENGTIEGGKLDNGEDVLAPYDHYKDTRTGVVVGPDSNPTLSFTSGSEGIPKGVLGRHFSLAYYFNWMSKRFNLTENDKFTMLSGIAHDPIQRDMFTPLFLGAQLYVPTQDDIGTPGRLAEWMSKYGCTVTHLTPAMGQLLTAQATTPFPKLHHAFFVGDILTKRDCLRLQTLAENCRIVNMYGTTETQRAVSYFEVKSKNDDPNFLKKLKDVMPAGKGMLNVQLLVVNRNDRTQICGIGEIGEIYVRAGGLAEGYRGLPELNKEKFVNNWFVEKDHWNYLDKDNGEPWRQFWLGPRDRLYRTGDLGRYLPNGDCECCGRADDQVKIRGFRIELGEIDTHISQHPLVRENITLVRKNADNEPTLITFMVPRFDKPDDLSKFQSDVPKEVETDPIVKGLIGYHLLSKDIRTFLKKRLASYAMPSLIVVMDKLPLNPNGKVDKPKLQFPTPKQLNLVAENTVSETDDSQFTNVEREVRDLWLSILPTKPASVSPDDSFFDLGGHSILATKMIFTLKKKLQVDLPLGTIFKYPTIKAFAAEIDRIKSSGGSSQGEVVENVTANYAEDAKKLVETLPSSYPSREYFVEPNSAEGKTTINVFVTGVTGFLGSYILADLLGRSPKNYSFKVFAHVRAKDEEAAFARLQKAGITYGTWNEKFASNIKVVLGDLSKSQFGLSDEKWMDLANTVDIIIHNGALVHWVYPYAKLRDPNVISTINVMSLAAVGKPKFFDFVSSTSTLDTEYYFNLSDKLVSEGKPGILESDDLMNSASGLTGGYGQSKWAAEYIIRRAGERGLRGCIVRPGYVTGASANGSSNTDDFLLRFLKGSVQLGKIPDIENSVNMVPVDHVARVVVATSLNPPKENELAVAQVTGHPRILFKDYLYTLHDYGYDVEIESYSKWKKSLEASVIDRNEENALYPLLHMVLDNLPESTKAPELDDRNAVASLKKDTAWTGVDWSNGIGVTPEEVGIYIAFLNKVGFLPPPTHNDKLPLPSIELTQAQISLVASGAGARGSSAAA
SIO_010081: YBR115C
subclass of: SO_0000673
so part of: YBR115C
location: complement(469748..473926)
location: region:469748-473926:-1
so has part: feature:469748-473926:-1:exon

NP_009673.1
type: Protein
SIO_000068: ncbiprotein

S000000319
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:469748-473926:-1:exon

YBR117C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TKL2
locus tag: YBR117C
so part of: sequence
location: complement(<474392..>476437)
location: region:474392-476437:-1
so has part: feature:474392-476437:-1:exon
subclass of: SO_0000010

852414
type: Gene
SIO_000068: ncbigene

position:474392:-1
position: 474392
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:476437:-1
position: 476437
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:474392-476437:-1:exon

YBR117C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TKL2
locus tag: YBR117C
product: transketolase TKL2
transcript id: NM_001178465.3
SIO_010081: YBR117C
subclass of: SO_0000673
so part of: YBR117C
location: complement(<474392..>476437)
location: region:474392-476437:-1
so has part: feature:474392-476437:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:474392-476437:-1:exon

YBR117C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TKL2
locus tag: YBR117C
EC number: 2.2.1.1
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0006098 pentose-phosphate shunt [PMID:7916691]
note: Transketolase; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids; TKL2 has a paralog, TKL1, that arose from the whole genome duplication
codon start: 1
product: transketolase TKL2
translation: MAQFSDIDKLAVSTLRLLSVDQVESAQSGHPGAPLGLAPVAHVIFKQLRCNPNNEHWINRDRFVLSNGHSCALLYSMLHLLGYDYSIEDLRQFRQVNSRTPGHPEFHSAGVEITSGPLGQGISNAVGMAIAQANFAATYNEDGFPISDSYTFAIVGDGCLQEGVSSETSSLAGHLQLGNLITFYDSNSISIDGKTSYSFDEDVLKRYEAYGWEVMEVDKGDDDMESISSALEKAKLSKDKPTIIKVTTTIGFGSLQQGTAGVHGSALKADDVKQLKKRWGFDPNKSFVVPQEVYDYYKKTVVEPGQKLNEEWDRMFEEYKTKFPEKGKELQRRLNGELPEGWEKHLPKFTPDDDALATRKTSQQVLTNMVQVLPELIGGSADLTPSNLTRWEGAVDFQPPITQLGNYAGRYIRYGVREHGMGAIMNGISAFGANYKPYGGTFLNFVSYAAGAVRLAALSGNPVIWVATHDSIGLGEDGPTHQPIETLAHLRAIPNMHVWRPADGNETSAAYYSAIKSGRTPSVVALSRQNLPQLEHSSFEKALKGGYVIHDVENPDIILVSTGSEVSISIDAAKKLYDTKKIKARVVSLPDFYTFDRQSEEYRFSVLPDGVPIMSFEVLATSSWGKYAHQSFGLDEFGRSGKGPEIYKLFDFTADGVASRAEKTINYYKGKQLLSPMGRAF
SIO_010081: YBR117C
subclass of: SO_0000673
so part of: YBR117C
location: complement(474392..476437)
location: region:474392-476437:-1
so has part: feature:474392-476437:-1:exon

NP_009675.3
type: Protein
SIO_000068: ncbiprotein

S000000321
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:474392-476437:-1:exon

YBR118W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TEF2
locus tag: YBR118W
so part of: sequence
location: <477671..>479047
location: region:477671-479047:1
so has part: feature:477671-479047:1:exon
subclass of: SO_0000010

852415
type: Gene
SIO_000068: ncbigene

position:477671:1
position: 477671
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:479047:1
position: 479047
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:477671-479047:1:exon

YBR118W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TEF2
locus tag: YBR118W
product: translation elongation factor EF-1 alpha
transcript id: NM_001178466.1
SIO_010081: YBR118W
subclass of: SO_0000673
so part of: YBR118W
location: <477671..>479047
location: region:477671-479047:1
so has part: feature:477671-479047:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:477671-479047:1:exon

YBR118W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TEF2
locus tag: YBR118W
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:25561732]
experiment: EXISTENCE:direct assay:GO:0005525 GTP binding [PMID:17925388]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:20032305]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0019003 GDP binding [PMID:17925388]
experiment: EXISTENCE:direct assay:GO:0051015 actin filament binding [PMID:25561732]
experiment: EXISTENCE:direct assay:GO:0051017 actin filament bundle assembly [PMID:19095653|PMID:25561732|PMID:16116436]
experiment: EXISTENCE:direct assay:GO:1904408 melatonin binding [PMID:31708896]
experiment: EXISTENCE:genetic interaction:GO:0006409 tRNA export from nucleus [PMID:10766739|PMID:17203074]
experiment: EXISTENCE:mutant phenotype:GO:0003746 translation elongation factor activity [PMID:10514524]
experiment: EXISTENCE:mutant phenotype:GO:0006409 tRNA export from nucleus [PMID:10766739|PMID:17203074]
experiment: EXISTENCE:mutant phenotype:GO:0006414 translational elongation [PMID:10514524]
experiment: EXISTENCE:mutant phenotype:GO:0051017 actin filament bundle assembly [PMID:16116436]
experiment: EXISTENCE:physical interaction:GO:0005739 mitochondrion [PMID:16962558]
note: Translational elongation factor EF-1 alpha; GTP-bound active form, binds to and delivers aminoacylated tRNA to the A-site of ribosomes for elongation of nascent polypeptides; moonlighting function as an actin binding and bundling protein; association with GTPase Rho1p on the vacuolar membrane may facilitate F-actin remodeling; involved in tRNA re-export from the nucleus; Tef2p-RFP levels increase during replicative aging
codon start: 1
product: translation elongation factor EF-1 alpha
translation: MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLGRFAVRDMRQTVAVGVIKSVDKTEKAAKVTKAAQKAAKK
SIO_010081: YBR118W
subclass of: SO_0000673
so part of: YBR118W
location: 477671..479047
location: region:477671-479047:1
so has part: feature:477671-479047:1:exon

NP_009676.1
type: Protein
SIO_000068: ncbiprotein

S000000322
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:477671-479047:1:exon

YBR119W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MUD1
locus tag: YBR119W
so part of: sequence
location: <479338..>480323
location: region:479338-480323:1
so has part: feature:479338-480323:1:exon
subclass of: SO_0000010

852416
type: Gene
SIO_000068: ncbigene

position:479338:1
position: 479338
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:480323:1
position: 480323
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:479338-480323:1:exon

YBR119W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MUD1
locus tag: YBR119W
product: Mud1p
transcript id: NM_001178467.1
SIO_010081: YBR119W
subclass of: SO_0000673
so part of: YBR119W
location: join(<479338..479345,479435..>480323)
location: region:479338-480323:1
so has part: feature:479338-479345:1:exon
so has part: feature:479435-480323:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:479338-479345:1:exon

position:479345:1
position: 479345
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:479435-480323:1:exon

position:479435:1
position: 479435
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YBR119W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MUD1
locus tag: YBR119W
experiment: EXISTENCE:direct assay:GO:0005685 U1 snRNP [PMID:9630245]
experiment: EXISTENCE:direct assay:GO:0071004 U2-type prespliceosome [PMID:16618970]
experiment: EXISTENCE:genetic interaction:GO:0000398 mRNA splicing, via spliceosome [PMID:8449403]
experiment: EXISTENCE:genetic interaction:GO:0030619 U1 snRNA binding [PMID:8449403]
experiment: EXISTENCE:physical interaction:GO:0030619 U1 snRNA binding [PMID:8849781]
note: U1 snRNP A protein; homolog of human U1-A; involved in nuclear mRNA splicing
codon start: 1
product: Mud1p
translation: MSALYFQNLPSRPANKENYTRLLLKHINPNNKYAINPSLPLPHNKLQISSQPLMLLDDQMGLLEVSISRSSKMTNQAFLTFVTQEEADRFLEKYTTTALKVQGRKVRMGKARTNSLLGLSIEMQKKKGNDETYNLDIKKVLKARKLKRKLRSDDICAKKFRLKRQIRRLKHKLRSRKVEEAEIDRIVKEFETRRLENMKSQQENLKQSQKPLKRAKVSNTMENPPNKVLLIQNLPSGTTEQLLSQILGNEALVEIRLVSVRNLAFVEYETVADATKIKNQLGSTYKLQNNDVTIGFAK
SIO_010081: YBR119W
subclass of: SO_0000673
so part of: YBR119W
location: join(479338..479345,479435..480323)
location: region:479338-480323:1
so has part: feature:479338-479345:1:exon
so has part: feature:479435-480323:1:exon

NP_009677.1
type: Protein
SIO_000068: ncbiprotein

S000000323
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:479338-479345:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:479435-480323:1:exon

YBR120C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CBP6
locus tag: YBR120C
so part of: sequence
location: complement(<480435..>480923)
location: region:480435-480923:-1
so has part: feature:480435-480923:-1:exon
subclass of: SO_0000010

852417
type: Gene
SIO_000068: ncbigene

position:480435:-1
position: 480435
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:480923:-1
position: 480923
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:480435-480923:-1:exon

YBR120C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CBP6
locus tag: YBR120C
product: Cbp6p
transcript id: NM_001178468.3
SIO_010081: YBR120C
subclass of: SO_0000673
so part of: YBR120C
location: complement(<480435..>480923)
location: region:480435-480923:-1
so has part: feature:480435-480923:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:480435-480923:-1:exon

YBR120C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CBP6
locus tag: YBR120C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005761 mitochondrial ribosome [PMID:21670217]
experiment: EXISTENCE:direct assay:GO:0043022 ribosome binding [PMID:21670217]
experiment: EXISTENCE:mutant phenotype:GO:0070131 positive regulation of mitochondrial translation [PMID:21670217]
experiment: EXISTENCE:physical interaction:GO:0034551 mitochondrial respiratory chain complex III assembly [PMID:21670217]
experiment: EXISTENCE:physical interaction:GO:0043022 ribosome binding [PMID:21670217]
experiment: EXISTENCE:physical interaction:GO:0061671 Cbp3p-Cbp6 complex [PMID:21670217]
note: Mitochondrial protein required for translation of the COB mRNA; forms a complex with Cbp3p that binds to mt ribosomes near the polypeptide tunnel exit and promotes efficient translation of the COB mRNA; Cbp3p-Cbp6p complex also interacts with newly synthesized cytochrome b (Cobp) and Cbp4p to promote assembly of Cobp into the cytochrome bc1 complex; Cbp3p-Cbp6p complex is sequestered if assembly of Complex III is blocked, downregulating COB mRNA translation
codon start: 1
product: Cbp6p
translation: MSSSQVVRDSAKKLVNLLEKYPKDRIHHLVSFRDVQIARFRRVAGLPNVDDKGKSIKEKKPSLDEIKSIINRTSGPLGLNKEMLTKIQNKMVDEKFTEESINEQIRALSTIMNNKFRNYYDIGDKLYKPAGNPQYYQRLINAVDGKKKESLFTAMRTVLFGK
SIO_010081: YBR120C
subclass of: SO_0000673
so part of: YBR120C
location: complement(480435..480923)
location: region:480435-480923:-1
so has part: feature:480435-480923:-1:exon

NP_009678.3
type: Protein
SIO_000068: ncbiprotein

S000000324
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:480435-480923:-1:exon

YBR121C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GRS1
locus tag: YBR121C
so part of: sequence
location: complement(<481364..>483367)
location: region:481364-483367:-1
so has part: feature:481364-483367:-1:exon
subclass of: SO_0000010

852418
type: Gene
SIO_000068: ncbigene

position:481364:-1
position: 481364
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:483367:-1
position: 483367
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:481364-483367:-1:exon

YBR121C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GRS1
locus tag: YBR121C
product: glycine--tRNA ligase
transcript id: NM_001178469.2
SIO_010081: YBR121C
subclass of: SO_0000673
so part of: YBR121C
location: complement(<481364..>483367)
location: region:481364-483367:-1
so has part: feature:481364-483367:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:481364-483367:-1:exon

YBR121C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GRS1
locus tag: YBR121C
EC number: 6.1.1.14
experiment: EXISTENCE:direct assay:GO:0004820 glycine-tRNA ligase activity [PMID:21877692]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:mutant phenotype:GO:0004820 glycine-tRNA ligase activity [PMID:10874035]
experiment: EXISTENCE:mutant phenotype:GO:0005737 cytoplasm [PMID:10874035]
experiment: EXISTENCE:mutant phenotype:GO:0005739 mitochondrion [PMID:10874035]
experiment: EXISTENCE:mutant phenotype:GO:0006353 DNA-templated transcription termination [PMID:10224248]
experiment: EXISTENCE:mutant phenotype:GO:0006426 glycyl-tRNA aminoacylation [PMID:10874035]
experiment: EXISTENCE:mutant phenotype:GO:0070150 mitochondrial glycyl-tRNA aminoacylation [PMID:10874035]
note: Cytoplasmic and mitochondrial glycyl-tRNA synthase; ligates glycine to the cognate anticodon-bearing tRNA; transcription termination factor that may interact with the 3'-end of pre-mRNA to promote 3'-end formation; GRS1 has a paralog, GRS2, that arose from the whole genome duplication; human homolog GARS implicated in Charcot-Marie-Tooth disease, can complement yeast null mutant
codon start: 1
product: glycine--tRNA ligase
translation: MSVEDIKKARAAVPFNREQLESVLRGRFFYAPAFDLYGGVSGLYDYGPPGCAFQNNIIDAWRKHFILEEDMLEVDCTMLTPYEVLKTSGHVDKFSDWMCRDLKTGEIFRADHLVEEVLEARLKGDQEARGLVEDANAAAKDDAEKKKRKKKVKQIKAVKLDDDVVKEYEEILAKIDGYSGPELGELMEKYDIGNPVTGETLESPRAFNLMFETAIGPSGQLKGYLRPETAQGQFLNFNKLLEFNNSKTPFASASIGKSFRNEISPRAGLLRVREFLMAEIEHFVDPLDKSHPKFNEIKDIKLSFLPRDVQEAGSTEPIVKTVGEAVASRMVDNETLGYFIARIYQFLMKIGVDESKLRFRQHMANEMAHYAADCWDGELKTSYGWIECVGCADRSAYDLTVHSKKTKEKLVVRQKLDNPIEVTKWEIDLTKKLFGPKFRKDAPKVESHLLNMSQDDLASKAELLKANGKFTIKVDGVDGEVELDDKLVKIEQRTKVEHVREYVPSVIEPSFGIGRIIYSVFEHSFWNRPEDNARSVLSFPPLVAPTKVLLVPLSNHKDLVPVTTEVAKILRKSQIPFKIDDSGVSIGKRYARNDELGTPFGVTIDFESAKDHSVTLRERDSTKQVRGSVENVIKAIRDITYNGASWEEGTKDLTPFIAQAEAEAETD
SIO_010081: YBR121C
subclass of: SO_0000673
so part of: YBR121C
location: complement(481364..483367)
location: region:481364-483367:-1
so has part: feature:481364-483367:-1:exon

NP_009679.2
type: Protein
SIO_000068: ncbiprotein

S000000325
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:481364-483367:-1:exon

YBR122C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: bL31m
gene: MRPL36
locus tag: YBR122C
gene synonym: bL31m
so part of: sequence
location: complement(<483970..>484503)
location: region:483970-484503:-1
so has part: feature:483970-484503:-1:exon
subclass of: SO_0000010

852419
type: Gene
SIO_000068: ncbigene

position:483970:-1
position: 483970
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:484503:-1
position: 484503
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:483970-484503:-1:exon

YBR122C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: bL31m
gene: MRPL36
locus tag: YBR122C
gene synonym: bL31m
product: mitochondrial 54S ribosomal protein YmL36
transcript id: NM_001178470.1
SIO_010081: YBR122C
subclass of: SO_0000673
so part of: YBR122C
location: complement(<483970..>484503)
location: region:483970-484503:-1
so has part: feature:483970-484503:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:483970-484503:-1:exon

YBR122C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: bL31m
gene: MRPL36
locus tag: YBR122C
gene synonym: bL31m
experiment: EXISTENCE:direct assay:GO:0003735 structural constituent of ribosome [PMID:12392552]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005762 mitochondrial large ribosomal subunit [PMID:12392552]
experiment: EXISTENCE:mutant phenotype:GO:0032543 mitochondrial translation [PMID:19339279]
note: Mitochondrial ribosomal protein of the large subunit; overproduction suppresses mutations in the COX2 leader peptide-encoding region
codon start: 1
product: mitochondrial 54S ribosomal protein YmL36
translation: MLKSIFAKRFASTGSYPGSTRITLPRRPAKKIQLGKSRPAIYHQFNVKMELSDGSVVIRRSQYPKGEIRLIQDQRNNPLWNPSRDDLVVVDANSGGSLDRFNKRYSSLFSVDSTTPNSSSETVELSEENKKKTQIKKEEKEDVSEKAFGMDDYLSLLDDSEQQIKSGKLASKKRDKK
SIO_010081: YBR122C
subclass of: SO_0000673
so part of: YBR122C
location: complement(483970..484503)
location: region:483970-484503:-1
so has part: feature:483970-484503:-1:exon

NP_009680.2
type: Protein
SIO_000068: ncbiprotein

S000000326
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:483970-484503:-1:exon

YBR123C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TFC1
locus tag: YBR123C
so part of: sequence
location: complement(<484742..>486691)
location: region:484742-486691:-1
so has part: feature:484742-486691:-1:exon
subclass of: SO_0000010

852421
type: Gene
SIO_000068: ncbigene

position:484742:-1
position: 484742
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:486691:-1
position: 486691
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:484742-486691:-1:exon

YBR123C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TFC1
locus tag: YBR123C
product: transcription factor TFIIIC subunit TFC1
transcript id: NM_001178471.3
SIO_010081: YBR123C
subclass of: SO_0000673
so part of: YBR123C
location: complement(<484742..>486691)
location: region:484742-486691:-1
so has part: feature:484742-486691:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:484742-486691:-1:exon

YBR123C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TFC1
locus tag: YBR123C
experiment: EXISTENCE:direct assay:GO:0000127 transcription factor TFIIIC complex [PMID:1474578|PMID:2002052|PMID:2052571|PMID:2180956]
experiment: EXISTENCE:direct assay:GO:0001002 RNA polymerase III type 1 promoter sequence-specific DNA binding [PMID:2404611|PMID:2649882]
experiment: EXISTENCE:direct assay:GO:0001003 RNA polymerase III type 2 promoter sequence-specific DNA binding [PMID:2404611]
experiment: EXISTENCE:direct assay:GO:0006383 transcription by RNA polymerase III [PMID:3633923|PMID:8464480]
experiment: EXISTENCE:direct assay:GO:0008301 DNA binding, bending [PMID:2002052]
experiment: EXISTENCE:direct assay:GO:0042791 5S class rRNA transcription by RNA polymerase III [PMID:2183033]
experiment: EXISTENCE:mutant phenotype:GO:0006383 transcription by RNA polymerase III [PMID:12533520]
note: Subunit of RNA polymerase III transcription initiation factor complex; one of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauA globular domain of TFIIIC that binds DNA at the BoxA promoter sites of tRNA and similar genes; human homolog is TFIIIC-63
codon start: 1
product: transcription factor TFIIIC subunit TFC1
translation: MPVEEPLATLSSIPDSSADQAPPLIADEFTLDLPRIPSLELPLNVSTKHSSIQKAIKMCGGIEKVKEAFKEHGPIESQHGLQLYLNDDTDSDGSKSYFNEHPVIGKRVPFRDESVILKVTMPKGTLSKNNNSVKDSIKSLKDSNKLRVTPVSIVDNTIKFREMSDFQIKLDNVPSAREFKSSFGSLEWNNFKSFVNSVPDNDSQPQENIGNLILDRSVKIPSTDFQLPPPPKLSMVGFPLLYKYKANPFAKKKKNGVTEVKGTYIKNYQLFVHDLSDKTVIPSQAHEQVLYDFEVAKKTKVYPGTKSDSKFYESLEECLKILRELFARRPIWVKRHLDGIVPKKIHHTMKIALALISYRFTMGPWRNTYIKFGIDPRSSVEYAQYQTEYFKIERKLLSSPIVKKNVPKPPPLVFESDTPGGIDSRFKFDGKRIPWYLMLQIDLLIGEPNIAEVFHNVEYLDKANELTGWFKELDLVKIRRIVKYELGCMVQGNYEYNKYKLKYFKTMLFVKESMVPENKNSEEGMGVNTNKDADGDINMDAGSQMSSNAIEEDKGIAAGDDFDDNGAITEEPDDAALENEEMDTDQNLKVPASIDDDVDDVDADEEEQESFDVKTASFQDIINKIAKLDPKTAETMKSELKGFVDEVDL
SIO_010081: YBR123C
subclass of: SO_0000673
so part of: YBR123C
location: complement(484742..486691)
location: region:484742-486691:-1
so has part: feature:484742-486691:-1:exon

NP_009681.3
type: Protein
SIO_000068: ncbiprotein

S000000327
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:484742-486691:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS216; Autonomously Replicating Sequence
so part of: sequence
location: 486707..486954
location: region:486707-486954:1
so has part: feature:486707-486954:1:region

S000118350
type: SGD
SIO_000068: sgd

position:486707:1
position: 486707
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:486954:1
position: 486954
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:486707-486954:1:region

YBR125C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: GCT1
gene: PTC4
locus tag: YBR125C
gene synonym: GCT1
so part of: sequence
location: complement(<487199..>488380)
location: region:487199-488380:-1
so has part: feature:487199-488380:-1:exon
subclass of: SO_0000010

852422
type: Gene
SIO_000068: ncbigene

position:487199:-1
position: 487199
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:488380:-1
position: 488380
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:487199-488380:-1:exon

YBR125C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: GCT1
gene: PTC4
locus tag: YBR125C
gene synonym: GCT1
product: type 2C protein phosphatase PTC4
transcript id: NM_001178473.1
SIO_010081: YBR125C
subclass of: SO_0000673
so part of: YBR125C
location: complement(<487199..>488380)
location: region:487199-488380:-1
so has part: feature:487199-488380:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:487199-488380:-1:exon

YBR125C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: GCT1
gene: PTC4
locus tag: YBR125C
gene synonym: GCT1
EC number: 3.1.3.16
experiment: EXISTENCE:direct assay:GO:0004722 protein serine/threonine phosphatase activity [PMID:10580002]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0006470 protein dephosphorylation [PMID:10580002]
note: Cytoplasmic type 2C protein phosphatase (PP2C); identified as a high-copy number suppressor of cnb1 mpk1 synthetic lethality; overexpression decreases high-osmolarity induced Hog1p phosphorylation and kinase activity
codon start: 1
product: type 2C protein phosphatase PTC4
translation: MGQLLSHPLTEKTIEYNEYKNNQASTGIVPRFYNCVGSMQGYRLTQEDAHLIRNENSVVYVRFFNPFIDKYETLSLNVFAVFDGHGGDDCSKFLSGGRHHRDGNGSSNGNGEPNAGLIKWIAYSFENHHYTSTTNNDSSKFKRSFNTLEGLVSQIFKDAFILQDEELYRHFANSSCGSTAVVACIINEESLYVANCGDSRCILSSKSNGIKTMSFDHKPQHIGELIRINDNGGTVSLGRVGGVLALSRAFSDFQFKRGVTYPHRRTKLTNITQNLTYGTPPQEAQVTVEPDVLMHKIDYSKDEFLVLACDGIWDIYNNKQLIHFIKYHLVSGTKLDTIITKLLDHGIAQANSNTGVGFDNMTAIIVVLNRKGETLQDWFNKMKTRLERERGLV
SIO_010081: YBR125C
subclass of: SO_0000673
so part of: YBR125C
location: complement(487199..488380)
location: region:487199-488380:-1
so has part: feature:487199-488380:-1:exon

NP_009683.1
type: Protein
SIO_000068: ncbiprotein

S000000329
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:487199-488380:-1:exon

YBR126C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: BYP1
alternative label: CIF1
alternative label: FDP1
alternative label: GGS1
alternative label: GLC6
alternative label: TSS1
gene: TPS1
locus tag: YBR126C
gene synonym: BYP1; CIF1; FDP1; GGS1; GLC6; TSS1
so part of: sequence
location: complement(<488905..>490392)
location: region:488905-490392:-1
so has part: feature:488905-490392:-1:exon
subclass of: SO_0000010

852423
type: Gene
SIO_000068: ncbigene

position:488905:-1
position: 488905
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:490392:-1
position: 490392
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:488905-490392:-1:exon

YBR126C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: BYP1
alternative label: CIF1
alternative label: FDP1
alternative label: GGS1
alternative label: GLC6
alternative label: TSS1
gene: TPS1
locus tag: YBR126C
gene synonym: BYP1; CIF1; FDP1; GGS1; GLC6; TSS1
product: alpha,alpha-trehalose-phosphate synthase (UDP-forming) TPS1
transcript id: NM_001178474.1
SIO_010081: YBR126C
subclass of: SO_0000673
so part of: YBR126C
location: complement(<488905..>490392)
location: region:488905-490392:-1
so has part: feature:488905-490392:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:488905-490392:-1:exon

YBR126C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: BYP1
alternative label: CIF1
alternative label: FDP1
alternative label: GGS1
alternative label: GLC6
alternative label: TSS1
gene: TPS1
locus tag: YBR126C
gene synonym: BYP1; CIF1; FDP1; GGS1; GLC6; TSS1
EC number: 2.4.1.15
experiment: EXISTENCE:direct assay:GO:0003825 alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity [PMID:1425702]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005946 alpha,alpha-trehalose-phosphate synthase complex (UDP-forming) [PMID:1425702]
experiment: EXISTENCE:direct assay:GO:0005992 trehalose biosynthetic process [PMID:1425702]
experiment: EXISTENCE:direct assay:GO:0044262 cellular carbohydrate metabolic process [PMID:1425702]
experiment: EXISTENCE:mutant phenotype:GO:0003825 alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity [PMID:9837904|PMID:1425702]
experiment: EXISTENCE:mutant phenotype:GO:0004805 trehalose-phosphatase activity [PMID:9837904]
experiment: EXISTENCE:mutant phenotype:GO:0005946 alpha,alpha-trehalose-phosphate synthase complex (UDP-forming) [PMID:1425702]
experiment: EXISTENCE:mutant phenotype:GO:0005992 trehalose biosynthetic process [PMID:1425702]
experiment: EXISTENCE:mutant phenotype:GO:0044262 cellular carbohydrate metabolic process [PMID:1425702]
experiment: EXISTENCE:mutant phenotype:GO:0071465 cellular response to desiccation [PMID:25456447]
experiment: EXISTENCE:physical interaction:GO:0005946 alpha,alpha-trehalose-phosphate synthase complex (UDP-forming) [PMID:9837904]
note: Synthase subunit of trehalose-6-P synthase/phosphatase complex; synthesizes the storage carbohydrate trehalose, which is critically important for survival of long-term desiccation; also found in a monomeric form; expression is induced by the stress response and repressed by the Ras-cAMP pathway; protein abundance increases in response to DNA replication stress and in response to prolonged exposure to boric acid; required for pseudohyphal growth
codon start: 1
product: alpha,alpha-trehalose-phosphate synthase (UDP-forming) TPS1
translation: MTTDNAKAQLTSSSGGNIIVVSNRLPVTITKNSSTGQYEYAMSSGGLVTALEGLKKTYTFKWFGWPGLEIPDDEKDQVRKDLLEKFNAVPIFLSDEIADLHYNGFSNSILWPLFHYHPGEINFDENAWLAYNEANQTFTNEIAKTMNHNDLIWVHDYHLMLVPEMLRVKIHEKQLQNVKVGWFLHTPFPSSEIYRILPVRQEILKGVLSCDLVGFHTYDYARHFLSSVQRVLNVNTLPNGVEYQGRFVNVGAFPIGIDVDKFTDGLKKESVQKRIQQLKETFKGCKIIVGVDRLDYIKGVPQKLHAMEVFLNEHPEWRGKVVLVQVAVPSRGDVEEYQYLRSVVNELVGRINGQFGTVEFVPIHFMHKSIPFEELISLYAVSDVCLVSSTRDGMNLVSYEYIACQEEKKGSLILSEFTGAAQSLNGAIIVNPWNTDDLSDAINEALTLPDVKKEVNWEKLYKYISKYTSAFWGENFVHELYSTSSSSTSSSATKN
SIO_010081: YBR126C
subclass of: SO_0000673
so part of: YBR126C
location: complement(488905..490392)
location: region:488905-490392:-1
so has part: feature:488905-490392:-1:exon

NP_009684.1
type: Protein
SIO_000068: ncbiprotein

S000000330
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:488905-490392:-1:exon

YBR126W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MEO1
locus tag: YBR126W-A
so part of: sequence
location: <490850..>491056
location: region:490850-491056:1
so has part: feature:490850-491056:1:exon
subclass of: SO_0000010

13393614
type: Gene
SIO_000068: ncbigene

position:490850:1
position: 490850
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:491056:1
position: 491056
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:490850-491056:1:exon

YBR126W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MEO1
locus tag: YBR126W-A
product: Meo1p
transcript id: NM_001270740.1
SIO_010081: YBR126W-A
subclass of: SO_0000673
so part of: YBR126W-A
location: <490850..>491056
location: region:490850-491056:1
so has part: feature:490850-491056:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:490850-491056:1:exon

YBR126W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MEO1
locus tag: YBR126W-A
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
note: hypothetical protein; identified by gene-trapping, microarray analysis, and genome-wide homology searches; mRNA identified as translated by ribosome profiling data; SWAT-GFP, seamless-GFP and mCherry fusion proteins localize to the endoplasmic reticulum; partially overlaps the dubious ORF YBR126W-B
codon start: 1
product: Meo1p
translation: MAITPDKQKKEQQHQPQNGPLDYAHICKCIAMFFVVAGVVLMFFETGLDPEQKEQIKRLHQLDGIPHA
SIO_010081: YBR126W-A
subclass of: SO_0000673
so part of: YBR126W-A
location: 490850..491056
location: region:490850-491056:1
so has part: feature:490850-491056:1:exon

NP_001257669.1
type: Protein
SIO_000068: ncbiprotein

S000028600
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:490850-491056:1:exon

YBR127C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: VAT2
gene: VMA2
locus tag: YBR127C
gene synonym: VAT2
so part of: sequence
location: complement(<491269..>492822)
location: region:491269-492822:-1
so has part: feature:491269-492822:-1:exon
subclass of: SO_0000010

852424
type: Gene
SIO_000068: ncbigene

position:491269:-1
position: 491269
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:492822:-1
position: 492822
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:491269-492822:-1:exon

YBR127C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: VAT2
gene: VMA2
locus tag: YBR127C
gene synonym: VAT2
product: H(+)-transporting V1 sector ATPase subunit B
transcript id: NM_001178475.3
SIO_010081: YBR127C
subclass of: SO_0000673
so part of: YBR127C
location: complement(<491269..>492822)
location: region:491269-492822:-1
so has part: feature:491269-492822:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:491269-492822:-1:exon

YBR127C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: VAT2
gene: VMA2
locus tag: YBR127C
gene synonym: VAT2
experiment: EXISTENCE:direct assay:GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain [PMID:2478556|PMID:2857169]
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:18048916|PMID:23836928|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0010494 cytoplasmic stress granule [PMID:26777405]
experiment: EXISTENCE:direct assay:GO:0045121 membrane raft [PMID:23836928]
experiment: EXISTENCE:direct assay:GO:1990816 vacuole-mitochondrion membrane contact site [PMID:25026036]
experiment: EXISTENCE:mutant phenotype:GO:0000425 pexophagy [PMID:31332264]
experiment: EXISTENCE:mutant phenotype:GO:0006874 cellular calcium ion homeostasis [PMID:10991947]
experiment: EXISTENCE:mutant phenotype:GO:0007035 vacuolar acidification [PMID:18048916|PMID:2141385]
experiment: EXISTENCE:mutant phenotype:GO:0046961 proton-transporting ATPase activity, rotational mechanism [PMID:2141385]
experiment: EXISTENCE:mutant phenotype:GO:0055085 transmembrane transport [PMID:2141385]
experiment: EXISTENCE:mutant phenotype:GO:1902906 proteasome storage granule assembly [PMID:23690178]
note: Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase; electrogenic proton pump found throughout the endomembrane system; contains nucleotide binding sites; also detected in the cytoplasm; protein abundance increases in response to DNA replication stress; human homolog ATP6V1B1, implicated in autosomal-recessive distal renal tubular acidosis (RTA) with sensorineural deafness, complements yeast null mutant
codon start: 1
product: H(+)-transporting V1 sector ATPase subunit B
translation: MVLSDKELFAINKKAVEQGFNVKPRLNYNTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTSGIDVKKTTVEFTGESLRIPVSEDMLGRIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYPPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEFLEKFEKTFITQGAYEDRTVFESLDQAWSLLRIYPKEMLNRISPKILDEFYDRARDDADEDEEDPDTRSSGKKKDASQEESLI
SIO_010081: YBR127C
subclass of: SO_0000673
so part of: YBR127C
location: complement(491269..492822)
location: region:491269-492822:-1
so has part: feature:491269-492822:-1:exon

NP_009685.3
type: Protein
SIO_000068: ncbiprotein

S000000331
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:491269-492822:-1:exon

YBR128C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: APG14
alternative label: CVT12
gene: ATG14
locus tag: YBR128C
gene synonym: APG14; CVT12
so part of: sequence
location: complement(<493081..>494115)
location: region:493081-494115:-1
so has part: feature:493081-494115:-1:exon
subclass of: SO_0000010

852425
type: Gene
SIO_000068: ncbigene

position:493081:-1
position: 493081
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:494115:-1
position: 494115
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:493081-494115:-1:exon

YBR128C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: APG14
alternative label: CVT12
gene: ATG14
locus tag: YBR128C
gene synonym: APG14; CVT12
product: Atg14p
transcript id: NM_001178476.1
SIO_010081: YBR128C
subclass of: SO_0000673
so part of: YBR128C
location: complement(<493081..>494115)
location: region:493081-494115:-1
so has part: feature:493081-494115:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:493081-494115:-1:exon

YBR128C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: APG14
alternative label: CVT12
gene: ATG14
locus tag: YBR128C
gene synonym: APG14; CVT12
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:16421251]
experiment: EXISTENCE:direct assay:GO:0000407 phagophore assembly site [PMID:16421251|PMID:23129774]
experiment: EXISTENCE:direct assay:GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I [PMID:11157979]
experiment: EXISTENCE:direct assay:GO:0120095 vacuole-isolation membrane contact site [PMID:23549786]
experiment: EXISTENCE:genetic interaction:GO:0016236 macroautophagy [PMID:9712845]
experiment: EXISTENCE:mutant phenotype:GO:0016236 macroautophagy [PMID:9712845|PMID:11157979|PMID:32788210]
experiment: EXISTENCE:mutant phenotype:GO:0030242 autophagy of peroxisome [PMID:21121900]
experiment: EXISTENCE:mutant phenotype:GO:0032258 cytoplasm to vacuole transport by the Cvt pathway [PMID:8901576]
experiment: EXISTENCE:mutant phenotype:GO:0034727 piecemeal microautophagy of the nucleus [PMID:18701704]
note: Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I; Atg14p targets complex I to the phagophore assembly site (PAS); required for localizing additional ATG proteins to the PAS; required for overflow degradation of misfolded proteins when ERAD is saturated; homolog of human Barkor; other members are Vps34, Vps15, and Vps30p
codon start: 1
product: Atg14p
translation: MHCPICHHRAHVVYCAHCINTSPSLLLKLKLDLILLKDENKELNGKVEQILNEAMNYDQLDIKRMEKKKDPLMNSLMKLDVLRMKKNNNLIRHRIEQLNERIYSKRNHISELKVEIDNYKCYKVGTGTDKLREQVEISDAKNKLAQVSKICESARDYKLNLLNNWFVIQKLQDNFQIPFAIAFQPLISLKNFRILPLAITNDSINIMWKYISFFSDILMIKLPYTNKICEQPMFEFSDSIQTVVQRLIKLIINILQICRHLKLVPSTPMDIPWLLDQYDVDGLFYNMVKRNKMKCRSVSLYWTFGMLYSMVLDNMNNPQRGHPARRTAPPPTVTGPHDRWYVVG
SIO_010081: YBR128C
subclass of: SO_0000673
so part of: YBR128C
location: complement(493081..494115)
location: region:493081-494115:-1
so has part: feature:493081-494115:-1:exon

NP_009686.1
type: Protein
SIO_000068: ncbiprotein

S000000332
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:493081-494115:-1:exon

YBR129C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: OPY1
locus tag: YBR129C
so part of: sequence
location: complement(<494353..>495339)
location: region:494353-495339:-1
so has part: feature:494353-495339:-1:exon
subclass of: SO_0000010

852426
type: Gene
SIO_000068: ncbigene

position:494353:-1
position: 494353
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:495339:-1
position: 495339
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:494353-495339:-1:exon

YBR129C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: OPY1
locus tag: YBR129C
product: Opy1p
transcript id: NM_001178477.1
SIO_010081: YBR129C
subclass of: SO_0000673
so part of: YBR129C
location: complement(<494353..>495339)
location: region:494353-495339:-1
so has part: feature:494353-495339:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:494353-495339:-1:exon

YBR129C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: OPY1
locus tag: YBR129C
experiment: EXISTENCE:direct assay:GO:0005546 phosphatidylinositol-4,5-bisphosphate binding [PMID:22562153]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22562153|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:22562153]
experiment: EXISTENCE:genetic interaction:GO:1902647 negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process [PMID:22562153]
experiment: EXISTENCE:mutant phenotype:GO:1902647 negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process [PMID:22562153]
note: hypothetical protein; overproduction blocks cell cycle arrest in the presence of mating pheromone; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
codon start: 1
product: Opy1p
translation: MIAGATAPSSQHEILIASNLIKKPSTSQNKTPTAQSSSGNNGAADGAPQGYHHHHHHHRHLWWPRTTDHQYWCVLRKNQFAYYKTRDEREAISVIPRFDILNFKISELDGILTVYTPSKDLIFKFPRGQNEKVGMELMHNWKIALEKFLSSPSGNESVTTGSDYDEEEDDDDLIVVDEKAGPSSSKHSCSLTMDEQLSREDKEFYRMFDPRNAEHQVCSGILYTKVKKKKLFNRAKWQKFNVELTNTSFNLYSFKTGKLKKSIKLDKIIDCIELDNNSKMKNDDTNFALITFDERLSFKAANDQDMVDWIINFKSGILIRKKLKAENI
SIO_010081: YBR129C
subclass of: SO_0000673
so part of: YBR129C
location: complement(494353..495339)
location: region:494353-495339:-1
so has part: feature:494353-495339:-1:exon

NP_009687.1
type: Protein
SIO_000068: ncbiprotein

S000000333
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:494353-495339:-1:exon

YBR130C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SHE3
locus tag: YBR130C
so part of: sequence
location: complement(<495592..>496869)
location: region:495592-496869:-1
so has part: feature:495592-496869:-1:exon
subclass of: SO_0000010

852427
type: Gene
SIO_000068: ncbigene

position:495592:-1
position: 495592
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:496869:-1
position: 496869
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:495592-496869:-1:exon

YBR130C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SHE3
locus tag: YBR130C
product: She3p
transcript id: NM_001178478.3
SIO_010081: YBR130C
subclass of: SO_0000673
so part of: YBR130C
location: complement(<495592..>496869)
location: region:495592-496869:-1
so has part: feature:495592-496869:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:495592-496869:-1:exon

YBR130C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SHE3
locus tag: YBR130C
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:10212145]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005934 cellular bud tip [PMID:11032818]
experiment: EXISTENCE:direct assay:GO:1990825 sequence-specific mRNA binding [PMID:28092367]
experiment: EXISTENCE:mutant phenotype:GO:0007533 mating type switching [PMID:8625407]
experiment: EXISTENCE:mutant phenotype:GO:0008298 intracellular mRNA localization [PMID:10212145|PMID:28092367]
experiment: EXISTENCE:mutant phenotype:GO:0048309 endoplasmic reticulum inheritance [PMID:14691136]
note: Protein adaptor between Myo4p and the She2p-mRNA complex; part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud; also required for cortical ER inheritance
codon start: 1
product: She3p
translation: MSDQDNTQTSSSKLAPHHNIFMANLESSPTKDRNTSSQNASSSRVIESLHDQIDMLTKTNLQLTTQSQNLLSKLELAQSKESKLLENLNLLKNENENLNSIFERKNKKLKELEKDYSELSNRYNEQKEKMDQLSKLAKNSSAIEQSCSEKLQNMEVNYNSLLESQNLYRDHYSDEISKLNEKIGLLELELSNQNLNYGSDTSSNSDIELNLNKFNDSVKDLKSLETEKDSKLSKIITHSLDELNLQSWLNLYQTNENLISTFAEKMDLKDVLKRNDEKISNKGAVVQTLKKNVQTQVESNNADALSSNNAQDMLPIKMVKLRKTPNTNDSSSNGNSSNNKRRSFYTASPLLSSGSIPKSASPVLPGVKRTASVRKPSSSSSKTNVTHNNDPSTSPTISVPPGVTRTVSSTHKKKGNSMVVHGAQS
SIO_010081: YBR130C
subclass of: SO_0000673
so part of: YBR130C
location: complement(495592..496869)
location: region:495592-496869:-1
so has part: feature:495592-496869:-1:exon

NP_009688.3
type: Protein
SIO_000068: ncbiprotein

S000000334
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:495592-496869:-1:exon

YBR131W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CVT16
gene: CCZ1
locus tag: YBR131W
gene synonym: CVT16
so part of: sequence
location: <497163..>499277
location: region:497163-499277:1
so has part: feature:497163-499277:1:exon
subclass of: SO_0000010

852428
type: Gene
SIO_000068: ncbigene

position:497163:1
position: 497163
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:499277:1
position: 499277
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:497163-499277:1:exon

YBR131W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CVT16
gene: CCZ1
locus tag: YBR131W
gene synonym: CVT16
product: Ccz1p
transcript id: NM_001178479.3
SIO_010081: YBR131W
subclass of: SO_0000673
so part of: YBR131W
location: <497163..>499277
location: region:497163-499277:1
so has part: feature:497163-499277:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:497163-499277:1:exon

YBR131W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CVT16
gene: CCZ1
locus tag: YBR131W
gene synonym: CVT16
experiment: EXISTENCE:direct assay:GO:0001786 phosphatidylserine binding [PMID:24413168]
experiment: EXISTENCE:direct assay:GO:0005085 guanyl-nucleotide exchange factor activity [PMID:20797862|PMID:24413168]
experiment: EXISTENCE:direct assay:GO:0005768 endosome [PMID:20797862]
experiment: EXISTENCE:direct assay:GO:0005770 late endosome [PMID:11069774]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0006914 autophagy [PMID:12208507]
experiment: EXISTENCE:direct assay:GO:0010314 phosphatidylinositol-5-phosphate binding [PMID:24413168]
experiment: EXISTENCE:direct assay:GO:0032266 phosphatidylinositol-3-phosphate binding [PMID:24413168]
experiment: EXISTENCE:direct assay:GO:0035658 Mon1-Ccz1 complex [PMID:24413168]
experiment: EXISTENCE:direct assay:GO:0043547 positive regulation of GTPase activity [PMID:20797862|PMID:24413168]
experiment: EXISTENCE:direct assay:GO:0097352 autophagosome maturation [PMID:12208507]
experiment: EXISTENCE:genetic interaction:GO:0044395 protein targeting to vacuolar membrane [PMID:23979137]
experiment: EXISTENCE:mutant phenotype:GO:0006623 protein targeting to vacuole [PMID:12364329]
experiment: EXISTENCE:mutant phenotype:GO:0007034 vacuolar transport [PMID:11590240]
experiment: EXISTENCE:mutant phenotype:GO:0016236 macroautophagy [PMID:19793921]
experiment: EXISTENCE:mutant phenotype:GO:0032258 cytoplasm to vacuole transport by the Cvt pathway [PMID:19793921]
experiment: EXISTENCE:mutant phenotype:GO:0044395 protein targeting to vacuolar membrane [PMID:23979137]
experiment: EXISTENCE:mutant phenotype:GO:0048278 vesicle docking [PMID:14662743]
experiment: EXISTENCE:physical interaction:GO:0035658 Mon1-Ccz1 complex [PMID:20797862]
note: Subunit of a heterodimeric guanine nucleotide exchange factor (GEF); subunit of the Mon1-Ccz1 GEF complex, which stimulates nucleotide exchange and activation of Ypt7p, a Rab family GTPase involved in membrane tethering and fusion events at the late endosome and vacuole; GEF activity is stimulated by membrane association and anionic phospholipids; involved in localizing Ypt7p to the vacuolar membrane; required for macroautophagy, the CVT pathway and mitophagy
codon start: 1
product: Ccz1p
translation: MRLHYITVFDPSRSTNENDTFKQLLLFHYFGTTDSIPSLNEKLSIIGVIQGIWSLTSSCVNKDGEDLEKIIELNNDIIFCIKVESRFFISLAISNISDDQSAIPLQYLSAYLWLSYRFFKLLNGSFSGFNKDFRKLTDLLNEFVIPFWNDIYLNLETVTNRSFTVMWPGFYKRANFQHSSYNPGEKNNVEESWDAIILQNILLDKKSYLGLKDILVYHLPKRTKAANRESMGTKTYGLVRNFTSDLNTLPDISNWLYHLHCTYGEISSHILTGNVHFKEELQVEEEQERSRDTNGRDEEESQEQQRREHQETTQNNTSELSLSERVIHNVTLPISFAYDAIHEVSTTTGVSGSLSMIMDYVPKPHWPFISSSNKSADKNNYSNSNDNANSNAPLMAQSEAVGGTIGNSRFGFLISPLNSDLLPSSYQALKLNLNFENSKDKEDFYNCLFWYFDDFLIVIVCDPDFNKICERDYLKDLSFQLCQSMECLNNEILNSQNCDNVESFAYVIRDNVTKEIDSSVPFGSPKFTSDESISTLQLAINGIDQFINDNSNSLSLANWNPITIMGGSNAISKKNTTEGFGNGVNDKTQKFKRKYLNFLNLMSAEKLWDLQVDVLQFLTSLQNSKRDPDYFQEERLLKLNNGVLCYIKENNSNLIIIIKNWFQNNGTSKAAKQRNRFSSDSSKGSSLFQSLGRDVTDWWESREI
SIO_010081: YBR131W
subclass of: SO_0000673
so part of: YBR131W
location: 497163..499277
location: region:497163-499277:1
so has part: feature:497163-499277:1:exon

NP_009689.3
type: Protein
SIO_000068: ncbiprotein

S000000335
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:497163-499277:1:exon

YBR132C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: AGP2
locus tag: YBR132C
so part of: sequence
location: complement(<499652..>501442)
location: region:499652-501442:-1
so has part: feature:499652-501442:-1:exon
subclass of: SO_0000010

852429
type: Gene
SIO_000068: ncbigene

position:499652:-1
position: 499652
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:501442:-1
position: 501442
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:499652-501442:-1:exon

YBR132C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: AGP2
locus tag: YBR132C
product: Agp2p
transcript id: NM_001178480.1
SIO_010081: YBR132C
subclass of: SO_0000673
so part of: YBR132C
location: complement(<499652..>501442)
location: region:499652-501442:-1
so has part: feature:499652-501442:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:499652-501442:-1:exon

YBR132C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: AGP2
locus tag: YBR132C
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:10545096]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:10545096]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:10545096]
experiment: EXISTENCE:mutant phenotype:GO:1902269 positive regulation of polyamine transmembrane transport [PMID:23755272]
experiment: EXISTENCE:mutant phenotype:GO:1902274 positive regulation of (R)-carnitine transmembrane transport [PMID:23755272]
note: Plasma membrane regulator of polyamine and carnitine transport; has similarity to transporters but lacks transport activity; may act as a sensor that transduces environmental signals; has a positive or negative regulatory effect on transcription of many transporter genes
codon start: 1
product: Agp2p
translation: MTKERMTIDYENDGDFEYDKNKYKTITTRIKSIEPSEGWLEPSGSVGHINTIPEAGDVHVDEHEDRGSSIDDDSRTYLLYFTETRRKLENRHVQLIAISGVIGTALFVAIGKALYRGGPASLLLAFALWCVPILCITVSTAEMVCFFPVSSPFLRLATKCVDDSLAVMASWNFWFLECVQIPFEIVSVNTIIHYWRDDYSAGIPLAVQVVLYLLISICAVKYYGEMEFWLASFKIILALGLFTFTFITMLGGNPEHDRYGFRNYGESPFKKYFPDGNDVGKSSGYFQGFLACLIQASFTIAGGEYISMLAGEVKRPRKVLPKAFKQVFVRLTFLFLGSCLCVGIVCSPNDPDLTAAINEARPGAGSSPYVIAMNNLKIRILPDIVNIALITAAFSAGNAYTYCSSRTFYGMALDGYAPKIFTRCNRHGVPIYSVAISLVWALVSLLQLNSNSAVVLNWLINLITASQLINFVVLCIVYLFFRRAYHVQQDSLPKLPFRSWGQPYTAIIGLVSCSAMILIQGYTVFFPKLWNTQDFLFSYLMVFINIGIYVGYKFIWKRGKDHFKNPHEIDFSKELTEIENHEIESSFEKFQYYSKA
SIO_010081: YBR132C
subclass of: SO_0000673
so part of: YBR132C
location: complement(499652..501442)
location: region:499652-501442:-1
so has part: feature:499652-501442:-1:exon

NP_009690.1
type: Protein
SIO_000068: ncbiprotein

S000000336
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:499652-501442:-1:exon

YBR133C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HSL7
locus tag: YBR133C
so part of: sequence
location: complement(<501804..>504287)
location: region:501804-504287:-1
so has part: feature:501804-504287:-1:exon
subclass of: SO_0000010

852431
type: Gene
SIO_000068: ncbigene

position:501804:-1
position: 501804
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:504287:-1
position: 504287
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:501804-504287:-1:exon

YBR133C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: HSL7
locus tag: YBR133C
product: protein arginine N-methyltransferase
transcript id: NM_001178481.1
SIO_010081: YBR133C
subclass of: SO_0000673
so part of: YBR133C
location: complement(<501804..>504287)
location: region:501804-504287:-1
so has part: feature:501804-504287:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:501804-504287:-1:exon

YBR133C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: HSL7
locus tag: YBR133C
EC number: 2.1.1.320
experiment: EXISTENCE:direct assay:GO:0000144 cellular bud neck septin ring [PMID:10490648|PMID:27053666]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005824 outer plaque of spindle pole body [PMID:11408575]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:10805747|PMID:11408575|PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0032174 cellular bud neck septin collar [PMID:23389636]
experiment: EXISTENCE:direct assay:GO:0035241 protein-arginine omega-N monomethyltransferase activity [PMID:16426232|PMID:18515076]
experiment: EXISTENCE:direct assay:GO:0035243 protein-arginine omega-N symmetric methyltransferase activity [PMID:18515076]
experiment: EXISTENCE:mutant phenotype:GO:0000086 G2/M transition of mitotic cell cycle [PMID:10490630]
experiment: EXISTENCE:mutant phenotype:GO:0000144 cellular bud neck septin ring [PMID:27053666]
experiment: EXISTENCE:mutant phenotype:GO:0030163 protein catabolic process [PMID:23042131]
experiment: EXISTENCE:mutant phenotype:GO:0051726 regulation of cell cycle [PMID:8647431]
note: Protein arginine N-methyltransferase; exhibits septin and Hsl1p-dependent localization to the bud neck in budded cells and periodic Hsl1p-dependent phosphorylation; required with Hsl1p, and Elm1p for the mother-bud neck recruitment, phosphorylation, and degradation of Swe1p; responsible for symmetric dimethylation of histone H4 on Arg3; relocalizes away from bud neck upon DNA replication stress; human homolog PRMT5 can complement yeast hsl7 mutant
codon start: 1
product: protein arginine N-methyltransferase
translation: MHSNVFVGVKPGFNHKQHSKKSRFLENVSSHSPELPSNYDYVLLPITTPRYKEIVGQVFKDFQRQSIQNWKPLQIPEPQLQDICIPPFNVKKLDNDDTPSYIGLLSSWLELESRDPNVRDLGLKVLLNECKYARFVGINKLILAPPRDLSNLQLYGQMIYRLLQNRIVFAAPALTISISLPLYEDSDPLATWELWNTVRKQCEYHPSLTISLALPRTRTPSYVLNRWLAEPVSCLLVSSSIFASNQYDYPVLHKFNQNLILKFQKVNGDSQILGNELCVILHGMEKYANNVKGGESAYLEYINYLLKKGDKVLNSNSNHQFLLQEDSRIMPPLKPHSDNLLNSTYLTFEKDLVKYDLYESAILEALQDLAPRASAKRPLVILVAGAGRGPLVDRTFKIISMLFMDSKVSIIAIEKNPQAYLYLQKRNFDCWDNRVKLIKEDMTKWQINEPSEKRIQIDLCISELLGSFGCNELSPECLWSIEKYHSHNDTIFIPRSYSSYIAPISSPLFYQKLSQTNRSLEAPWIVHRVPYCILSSRVNEVWRFEHPMAQKDTVQDEDDFTVEFSQSSLNEFKIKHRGEIHGFIGFFSANLYNNIFLSTLPNDSTVRLKFSEETLMNTRREENLIKKCDHTPNMTSWSPIIFPLKQPISFIDDSELSVLMSRIHSDTEQKVWYEWSLESFIYLMLSNYTSAVTAASMTIPRSIVTDDTKTLAHNRHYSATTNQKLDNQIDLDQDIENEEEQGFLSNLETGWQSVQDIHGLSETAKPDHLDSINKPMFDLKSTKALEPSNELPRHEDLEEDVPEVHVRVKTSVSTLHNVCGRAFSLPL
SIO_010081: YBR133C
subclass of: SO_0000673
so part of: YBR133C
location: complement(501804..504287)
location: region:501804-504287:-1
so has part: feature:501804-504287:-1:exon

NP_009691.1
type: Protein
SIO_000068: ncbiprotein

S000000337
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:501804-504287:-1:exon

YBR135W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CKS1
locus tag: YBR135W
so part of: sequence
location: <504854..>505306
location: region:504854-505306:1
so has part: feature:504854-505306:1:exon
subclass of: SO_0000010

852432
type: Gene
SIO_000068: ncbigene

position:504854:1
position: 504854
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:505306:1
position: 505306
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:504854-505306:1:exon

YBR135W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CKS1
locus tag: YBR135W
product: cyclin-dependent protein kinase regulatory subunit CKS1
transcript id: NM_001178483.3
SIO_010081: YBR135W
subclass of: SO_0000673
so part of: YBR135W
location: <504854..>505306
location: region:504854-505306:1
so has part: feature:504854-505306:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:504854-505306:1:exon

YBR135W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CKS1
locus tag: YBR135W
experiment: EXISTENCE:direct assay:GO:0000307 cyclin-dependent protein kinase holoenzyme complex [PMID:2664468]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0030295 protein kinase activator activity [PMID:10913169]
experiment: EXISTENCE:direct assay:GO:0042393 histone binding [PMID:20855529]
experiment: EXISTENCE:direct assay:GO:0043130 ubiquitin binding [PMID:17198374]
experiment: EXISTENCE:direct assay:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:20516216]
experiment: EXISTENCE:mutant phenotype:GO:0006357 regulation of transcription by RNA polymerase II [PMID:15629725]
experiment: EXISTENCE:mutant phenotype:GO:0007346 regulation of mitotic cell cycle [PMID:2664468|PMID:8491379]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:20516216]
note: Cyclin-dependent protein kinase regulatory subunit and adaptor; interacts with Cdc28p (aka Cdk1p); required for G1/S and G2/M phase transitions and budding; mediates phosphorylation and degradation of Sic1p; modulates proteolysis of M-phase targets through interactions with the proteasome; role in transcriptional regulation, recruiting proteasomal subunits to target gene promoters; human homologs CKS1B and CKS2 can each complement yeast cks1 null mutant
codon start: 1
product: cyclin-dependent protein kinase regulatory subunit CKS1
translation: MYHHYHAFQGRKLTDQERARVLEFQDSIHYSPRYSDDNYEYRHVMLPKAMLKVIPSDYFNSEVGTLRILTEDEWRGLGITQSLGWEHYECHAPEPHILLFKRPLNYEAELRAATAAAQQQQQQQQQQQQQQQQHQTQSISNDMQVPPQIS
SIO_010081: YBR135W
subclass of: SO_0000673
so part of: YBR135W
location: 504854..505306
location: region:504854-505306:1
so has part: feature:504854-505306:1:exon

NP_009693.3
type: Protein
SIO_000068: ncbiprotein

S000000339
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:504854-505306:1:exon

YBR136W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ESR1
alternative label: RAD31
alternative label: SAD3
gene: MEC1
locus tag: YBR136W
gene synonym: ESR1; RAD31; SAD3
so part of: sequence
location: <505668..>512774
location: region:505668-512774:1
so has part: feature:505668-512774:1:exon
subclass of: SO_0000010

852433
type: Gene
SIO_000068: ncbigene

position:505668:1
position: 505668
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:512774:1
position: 512774
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:505668-512774:1:exon

YBR136W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ESR1
alternative label: RAD31
alternative label: SAD3
gene: MEC1
locus tag: YBR136W
gene synonym: ESR1; RAD31; SAD3
product: protein kinase MEC1
transcript id: NM_001178484.3
SIO_010081: YBR136W
subclass of: SO_0000673
so part of: YBR136W
location: <505668..>512774
location: region:505668-512774:1
so has part: feature:505668-512774:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:505668-512774:1:exon

YBR136W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ESR1
alternative label: RAD31
alternative label: SAD3
gene: MEC1
locus tag: YBR136W
gene synonym: ESR1; RAD31; SAD3
EC number: 2.7.11.1
experiment: EXISTENCE:direct assay:GO:0000723 telomere maintenance [PMID:15721260]
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:11095737]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:23934994]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:genetic interaction:GO:0000722 telomere maintenance via recombination [PMID:17202155]
experiment: EXISTENCE:genetic interaction:GO:0004672 protein kinase activity [PMID:21841787]
experiment: EXISTENCE:mutant phenotype:GO:0006260 DNA replication [PMID:10511542]
experiment: EXISTENCE:mutant phenotype:GO:0006310 DNA recombination [PMID:10511543]
experiment: EXISTENCE:mutant phenotype:GO:0007131 reciprocal meiotic recombination [PMID:10511543]
experiment: EXISTENCE:mutant phenotype:GO:0042770 signal transduction in response to DNA damage [PMID:17693258]
experiment: EXISTENCE:mutant phenotype:GO:1901857 positive regulation of cellular respiration [PMID:31073026]
experiment: EXISTENCE:mutant phenotype:GO:2000105 positive regulation of DNA-templated DNA replication [PMID:23307868]
note: Genome integrity checkpoint protein and PI kinase superfamily member; Mec1p and Dun1p function in same pathway to regulate dNTP pools and telomere length; signal transducer required for cell cycle arrest and transcriptional responses to damaged or unreplicated DNA; facilitates replication fork progression and regulates P-body formation under replication stress; promotes interhomolog recombination by phosphorylating Hop1p; associates with shortened, dysfunctional telomeres
codon start: 1
product: protein kinase MEC1
translation: MESHVKYLDELILAIKDLNSGVDSKVQIKKVPTDPSSSQEYAKSLKILNTLIRNLKDQRRNNIMKNDTIFSKTVSALALLLEYNPFLLVMKDSNGNFEIQRLIDDFLNISVLNYDNYHRIWFMRRKLGSWCKACVEFYGKPAKFQLTAHFENTMNLYEQALTEVLLGKTELLKFYDTLKGLYILLYWFTSEYSTFGNSIAFLDSSLGFTKFDFNFQRLIRIVLYVFDSCELAALEYAEIQLKYISLVVDYVCNRTISTALDAPALVCCEQLKFVLTTMHHFLDNKYGLLDNDPTMAKGILRLYSLCISNDFSKCFVDHFPIDQWADFSQSEHFPFTQLTNKALSIVYFDLKRRSLPVEALKYDNKFNIWVYQSEPDSSLKNVTSPFDDRYKQLEKLRLLVLKKFNKTERGTLLKYRVNQLSPGFFQRAGNDFKLILNEASVSIQTCFKTNNITRLTSWTVILGRLACLESEKFSGTLPNSTKDMDNWYVCHLCDIEKTGNPFVRINPNRPEAAGKSEIFRILHSNFLSHPNIDEFSESLLSGILFSLHRIFSHFQPPKLTDGNGQINKSFKLVQKCFMNSNRYLRLLSTRIIPLFNISDSHNSEDEHTATLIKFLQSQKLPVVKENLVIAWTQLTLTTSNDVFDTLLLKLIDIFNSDDYSLRIMMTLQIKNMAKILKKTPYQLLSPILPVLLRQLGKNLVERKVGFQNLIELLGYSSKTILDIFQRYIIPYAIIQYKSDVLSEIAKIMCDGDTSLINQMKVNLLKKNSRQIFAVALVKHGLFSLDILETLFLNRAPTFDKGYITAYLPDYKTLAEITKLYKNSVTKDASDSENANMILCSLRFLITNFEKDKRHGSKYKNINNWTDDQEQAFQKKLQDNILGIFQVFSSDIHDVEGRTTYYEKLRVINGISFLIIYAPKKSIISALAQISICLQTGLGLKEVRYEAFRCWHLLVRHLNDEELSTVIDSLIAFILQKWSEFNGKLRNIVYSILDTLIKEKSDLILKLKPYTTLALVGKPELGILARDGQFARMVNKIRSTTDLIPIFANNLKSSNKYVINQNLDDIEVYLRRKQTERSIDFTPKKVGQTSDITLVLGALLDTSHKFRNLDKDLCEKCAKCISMIGVLDVTKHEFKRTTYSENEVYDLNDSVQTIKFLIWVINDILVPAFWQSENPSKQLFVALVIQESLKYCGLSSESWDMNHKELYPNEAKLWEKFNSVSKTTIYPLLSSLYLAQSWKEYVPLKYPSNNFKEGYKIWVKRFTLDLLKTGTTENHPLHVFSSLIREDDGSLSNFLLPYISLDIIIKAEKGTPYADILNGIIIEFDSIFTCNLEGMNNLQVDSLRMCYESIFRVFEYCKKWATEFKQNYSKLHGTFIIKDTKTTNMLLRIDEFLRTTPSDLLAQRSLETDSFERSALYLEQCYRQNPHDKNQNGQLLKNLQITYEEIGDIDSLDGVLRTFATGNLVSKIEELQYSENWKLAQDCFNVLGKFSDDPKTTTRMLKSMYDHQLYSQIISNSSFHSSDGKISLSPDVKEWYSIGLEAANLEGNVQTLKNWVEQIESLRNIDDREVLLQYNIAKALIAISNEDPLRTQKYIHNSFRLIGTNFITSSKETTLLKKQNLLMKLHSLYDLSFLSSAKDKFEYKSNTTILDYRMERIGADFVPNHYILSMRKSFDQLKMNEQADADLGKTFFTLAQLARNNARLDIASESLMHCLERRLPQAELEFAEILWKQGENDRALKIVQEIHEKYQENSSVNARDRAAVLLKFTEWLDLSNNSASEQIIKQYQDIFQIDSKWDKPYYSIGLYYSRLLERKKAEGYITNGRFEYRAISYFLLAFEKNTAKVRENLPKVITFWLDIAAASISEAPGNRKEMLSKATEDICSHVEEALQHCPTYIWYFVLTQLLSRLLHSHQSSAQIIMHILLSLAVEYPSHILWYITALVNSNSSKRVLRGKHILEKYRQHSQNPHDLVSSALDLTKALTRVCLQDVKSITSRSGKSL…
SIO_010081: YBR136W
subclass of: SO_0000673
so part of: YBR136W
location: 505668..512774
location: region:505668-512774:1
so has part: feature:505668-512774:1:exon

NP_009694.3
type: Protein
SIO_000068: ncbiprotein

S000000340
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:505668-512774:1:exon

YBR137W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBR137W
so part of: sequence
location: <513044..>513583
location: region:513044-513583:1
so has part: feature:513044-513583:1:exon
subclass of: SO_0000010

852434
type: Gene
SIO_000068: ncbigene

position:513044:1
position: 513044
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:513583:1
position: 513583
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:513044-513583:1:exon

YBR137W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBR137W
product: uncharacterized protein
transcript id: NM_001178485.2
SIO_010081: YBR137W
subclass of: SO_0000673
so part of: YBR137W
location: <513044..>513583
location: region:513044-513583:1
so has part: feature:513044-513583:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:513044-513583:1:exon

YBR137W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBR137W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11266464]
experiment: EXISTENCE:direct assay:GO:0072380 TRC complex [PMID:20850366]
experiment: EXISTENCE:genetic interaction:GO:0006620 post-translational protein targeting to endoplasmic reticulum membrane [PMID:25288638]
note: Protein with a role in ER delivery of tail-anchored membrane proteins; interacts with Sgt2p; binds to the TRC complex, which inserts proteins into the ER membrane; interacts with Msn5p karyopherin; YBR137W is not an essential gene
codon start: 1
product: uncharacterized protein
translation: MVVLDKKLLERLTSRKVPLEELEDMEKRCFLSTFTYQDAFDLGTYIRNAVKENFPEKPVAIDISLPNGHCLFRTVTYGGSALDNDFWIQRKKKTALRFGHSSFYMGCKKGDKTPEEKFFVDSKEYAFHGGAVLIQSERSDYPYACLTISGLKQEEDHLMAVSSLIAFANESLEEDLNLD
SIO_010081: YBR137W
subclass of: SO_0000673
so part of: YBR137W
location: 513044..513583
location: region:513044-513583:1
so has part: feature:513044-513583:1:exon

NP_009695.2
type: Protein
SIO_000068: ncbiprotein

S000000341
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:513044-513583:1:exon

YBR138C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBR138C
so part of: sequence
location: complement(<513762..>515336)
location: region:513762-515336:-1
so has part: feature:513762-515336:-1:exon
subclass of: SO_0000010

852435
type: Gene
SIO_000068: ncbigene

position:513762:-1
position: 513762
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:515336:-1
position: 515336
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:513762-515336:-1:exon

YBR138C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBR138C
product: uncharacterized protein
transcript id: NM_001178486.2
SIO_010081: YBR138C
subclass of: SO_0000673
so part of: YBR138C
location: complement(<513762..>515336)
location: region:513762-515336:-1
so has part: feature:513762-515336:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:513762-515336:-1:exon

YBR138C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBR138C
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
note: Cytoplasmic hypothetical protein; APCC(Cdh1) substrate; potentially phosphorylated by Cdc28p; YBR138C is not an essential gene
codon start: 1
product: uncharacterized protein
translation: MEKDQIQPRVLESVDTNSLSLLSSNTSSNMNSNTNNKLSIIASDISTGSVLSRPLTPPVVQDIENNSMLQWQFEKKEFIFDSNSTPSKQAKPLQRNSPYQGNSQSENQNQQLLNVRKRRSQLIGAKPKIPSKLYQSVSKLDLIDDKSFTSLPIAPPCNIETNEDDSGNNEYNNNKKRPRLNPVNELRVHNNKRNRYVSYGPSLDTKNYELTENTSQDIPPLVLVEDYIPYTQSKSTKKMVSISDLKSKLSKRRDNHIPLRVKNSYSEINKETNRNSFEPNSLTLIPHILRNTEENRDESNNPLDFIKEEIEISDISIPNSIENMVVNLVNIPSSNKSYDDLYLSELNVHSQLRKCVICEKALYEISSRLLNSGYYKEIVCEQCTVRYEEAAKIFENCEFESSMDESNLSSGTFSDLENSAEPFHLSTDVPKKINRHIEDNKIDLKKEISKKKDSFSKELIERLQLQLLENDKSIKHHFNKDAMGSKSMNWFLEARRKLKWKWRINGLLPHFLRNQNSDRLNFQP
SIO_010081: YBR138C
subclass of: SO_0000673
so part of: YBR138C
location: complement(513762..515336)
location: region:513762-515336:-1
so has part: feature:513762-515336:-1:exon

NP_009696.2
type: Protein
SIO_000068: ncbiprotein

S000000342
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:513762-515336:-1:exon

YBR139W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ATG42
locus tag: YBR139W
so part of: sequence
location: <515664..>517190
location: region:515664-517190:1
so has part: feature:515664-517190:1:exon
subclass of: SO_0000010

852436
type: Gene
SIO_000068: ncbigene

position:515664:1
position: 515664
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:517190:1
position: 517190
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:515664-517190:1:exon

YBR139W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ATG42
locus tag: YBR139W
product: carboxypeptidase C
transcript id: NM_001178487.3
SIO_010081: YBR139W
subclass of: SO_0000673
so part of: YBR139W
location: <515664..>517190
location: region:515664-517190:1
so has part: feature:515664-517190:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:515664-517190:1:exon

YBR139W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ATG42
locus tag: YBR139W
EC number: 3.4.16.5
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:14562095|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0000328 fungal-type vacuole lumen [PMID:29514932]
experiment: EXISTENCE:direct assay:GO:0017171 serine hydrolase activity [PMID:14645503]
experiment: EXISTENCE:genetic interaction:GO:0004185 serine-type carboxypeptidase activity [PMID:29514932]
experiment: EXISTENCE:genetic interaction:GO:0016236 macroautophagy [PMID:29514932]
experiment: EXISTENCE:genetic interaction:GO:0031638 zymogen activation [PMID:29514932]
experiment: EXISTENCE:genetic interaction:GO:0046938 phytochelatin biosynthetic process [PMID:17408619]
note: Vacuolar serine-type carboxypeptidase; involved, along with functional homolog Prc1p, in vacuolar zymogen activation, breakdown of the autophagic body, and autophagosome-dependent protein synthesis; role in phytochelatin synthesis; localizes to the vacuole lumen; expression induced by nitrogen limitation in a GLN3, GAT1-independent manner; N-glycosylated
codon start: 1
product: carboxypeptidase C
translation: MKYLNLVFVLQLLISIKYASFGRAFSLFEDDTTFANLDKQLKLPQNTQQTLKLDRLNHDDPLFTTFISSVDTDYSLRLRTVDPSKLGIDTVKQWSGYMDYKDSKHFFYWFFESRNDPANDPIILWLNGGPGCSSFTGLLFELGPSSIGADMKPIHNPYSWNNNASMIFLEQPLGVGFSYGDEKVSSTKLAGKDAYIFLELFFEAFPHLRSNDFHIAGESYAGHYIPQIAHEIVVKNPERTFNLTSVMIGNGITDPLIQADYYEPMACGKGGYHPVLSSEECEKMSKAAGRCRRLNKLCYASKSSLPCIVATAYCDSALLEPYINTGLNVYDIRGPCEDNSTDGMCYTGLRYVDQYMNFPEVQETLGSDVHNYSGCDNDVFTGFLFTGDGSKPFQQYIAELLNHNIPVLIYAGDKDYICNWLGNHAWSNELEWINKRRYQRRMLRPWVSKETGEELGQVKNYGPFTFLRIYDAGHMVPYDQPEASLEMVNSWISGNRAFSDLSTLENAS
SIO_010081: YBR139W
subclass of: SO_0000673
so part of: YBR139W
location: 515664..517190
location: region:515664-517190:1
so has part: feature:515664-517190:1:exon

NP_009697.3
type: Protein
SIO_000068: ncbiprotein

S000000343
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:515664-517190:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS217; Autonomously replicating sequence
so part of: sequence
location: 517185..517386
location: region:517185-517386:1
so has part: feature:517185-517386:1:region

S000178050
type: SGD
SIO_000068: sgd

position:517185:1
position: 517185
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:517386:1
position: 517386
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:517185-517386:1:region

YBR140C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: GLC1
alternative label: PPD1
gene: IRA1
locus tag: YBR140C
gene synonym: GLC1; PPD1
so part of: sequence
location: complement(<517350..>526628)
location: region:517350-526628:-1
so has part: feature:517350-526628:-1:exon
subclass of: SO_0000010

852437
type: Gene
SIO_000068: ncbigene

position:517350:-1
position: 517350
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:526628:-1
position: 526628
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:517350-526628:-1:exon

YBR140C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: GLC1
alternative label: PPD1
gene: IRA1
locus tag: YBR140C
gene synonym: GLC1; PPD1
product: GTPase-activating protein IRA1
transcript id: NM_001178488.3
SIO_010081: YBR140C
subclass of: SO_0000673
so part of: YBR140C
location: complement(<517350..>526628)
location: region:517350-526628:-1
so has part: feature:517350-526628:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:517350-526628:-1:exon

YBR140C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: GLC1
alternative label: PPD1
gene: IRA1
locus tag: YBR140C
gene synonym: GLC1; PPD1
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:mutant phenotype:GO:0005096 GTPase activator activity [PMID:2178777]
experiment: EXISTENCE:mutant phenotype:GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [PMID:2540426]
experiment: EXISTENCE:mutant phenotype:GO:0016020 membrane [PMID:1875942]
experiment: EXISTENCE:mutant phenotype:GO:0043547 positive regulation of GTPase activity [PMID:2178777]
experiment: EXISTENCE:mutant phenotype:GO:0045761 regulation of adenylate cyclase activity [PMID:1875942]
experiment: EXISTENCE:mutant phenotype:GO:0046580 negative regulation of Ras protein signal transduction [PMID:15339905]
note: GTPase-activating protein; negatively regulates RAS by converting it from GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions, mediates membrane association of adenylate cyclase; mutations cause catalase T deficiency, defective glycogen synthesis and defective trehalose accumulation; IRA1 has a paralog, IRA2, that arose from the whole genome duplication; defects in human homolog NF1 are associated with neurofibromatosis
codon start: 1
product: GTPase-activating protein IRA1
translation: MNQSDPQDKKNFPMEYSLTKHLFFDRLLLVLPIESNLKTYADVEADSVFNSCRSIILNIAITKDLNPIIENTLGLIDLIVQDEEITSDNITDDIAHSILVLLRLLSDVFEYYWDQNNDFKKIRNDNYKPGFSSHRPNFHTSRPKHTRINPALATMLLCKISKLKFNTRTLKVLQNMSHHLSGSATISKSSILPDSQEFLQKRNYPAYTEKIDLTIDYIQRFISASNHVEFTKCVKTKVVAPLLISHTSTELGVVNHLDLFGCEYLTDKNLLAYLDILQHLSSYMKRTIFHSLLLYYASKAFLFWIMARPKEYVKIYNNLISSDYNSPSSSSDNGGSNNSDKTSISQLVSLLFDDVYSTFSVSSLLTNVNNDHHYHLHHSSSSSKTTNTNSPNSISKTSIKQSSVNASGNVSPSQFSTGNDASPTSPMASLSSPLNTNILGYPLSPITSTLGQANTSTSTTAATTKTDADTPSTMNTNNNNNNNNSANLNNIPQRIFSLDDISSFNSSRKSLNLDDSNSLFLWDTSQHSNASMTNTNMHAGVNNSQSQNDQSSLNYMENIMELYSNYTGSELSSHTAILRFLVVLTLLDSEVYDEMNSNSYRKISEPIMNINPKDSNTSSWGSASKNPSIRHLTHGLKKLTLQQGRKRNVKFLTYLIRNLNGGQFVSDVSLIDSIRSILFLMTMTSSISQIDSNIASVIFSKRFYNLLGQNLEVGTNWNSATANTFISHCVERNPLTHRRLQLEFFASGLQLDSDLFLRHLQLEKELNHIDLPKISLYTEGFRVFFHLVSTKKLHEDIAEKTSSVLKRLFCIIADILLKATPYFDDNVTKIIASILDGHILDQFDAARTLSNDDHVSFDAATSVYTEPTEIIHNSSDASLVSSLSQSPLSINSGSNITNTRTWDIQSILPTLSNRSSASDLSLSNILTNPLEAQQNNNANLLAHRLSGVPTTKRYASPNDSERSRQSPYSSPPQLQQSDLPSPLSVLSSSAGFSSNHSITATPTILKNIKSPKPNKTKKIADDKQLKQPSYSRVILSDNDEARKIMMNIFSIFKRMTNWFIRPDANTEFPKTFTDIIKPLFVSILDSNQRLQVTARAFIEIPLSYIATFEDIDNDLDPRVLNDHYLLCTYAVTLFASSLFDLKLENAKREMLLDIIVKFQRVRSYLSNLAEKHNLVQAIITTERLTLPLLVGAVGSGIFISLYCSRGNTPRLIKISCCEFLRSLRFYQKYVGALDQYSIYNIDFIDAMAQDNFTASGSVALQRRLRNNILTYIKGSDSILLDSMDVIYKKWFYFSCSKSVTQEELVDFRSLAGILASMSGILSDMQELEKSKSAPDNEGDSLSFESRNPAYEVHKSLKLELTKKMNFFISKQCQWLNNPNLLTRENSRDILSIELHPLSFNLLFNNLGLKIDELMSIDLSKSHEDSSFVLLEQIIIIIRTILKRDDDEKIMLLFSTDLLDAVDKLIEIVEKISIKSSKYYKGIIQMSKMFRAFEHSEKNLGISNHFHLKNKWLKLVIGWFKLSINKDYDFENLSRPLREMDLQKRDEDFLYIDTSIESAKALAYLTHNVPLEIPPSSSKEDWNRSSTVSFGNHFTILLKGLEKSADLNQFPVSLRHKISILNENVIIALTNLSNANVNVSLKFTLPMGYSPNKDIRIAFLRVFIDIVTNYPVNPEKHEMDKMLAIDDFLKYIIKNPILAFFGSLACSPADVDLYAGGFLNAFDTRNASHILVTELLKQEIKRAARSDDILRRNSCATRALSLYTRSRGNKYLIKTLRPVLQGIVDNKESFEIDKMKPGSENSEKMLDLFEKYMTRLIDAITSSIDDFPIELVDICKTIYNAASVNFPEYAYIAVGSFVFLRFIGPALVSPDSENIIIVTHAHDRKPFITLAKVIQSLANGRENIFKKDILVSKEEFLKTCSDKIFNFLSELCKIPTNNFTVNVREDPTPISFDYSFLHKFFYLNEFTIRKEIINESKLPGEFSFLKNTVMLNDKILGVLGQ…
SIO_010081: YBR140C
subclass of: SO_0000673
so part of: YBR140C
location: complement(517350..526628)
location: region:517350-526628:-1
so has part: feature:517350-526628:-1:exon

NP_009698.3
type: Protein
SIO_000068: ncbiprotein

S000000344
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:517350-526628:-1:exon

YBR141C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: BMT2
locus tag: YBR141C
so part of: sequence
location: complement(<527025..>528038)
location: region:527025-528038:-1
so has part: feature:527025-528038:-1:exon
subclass of: SO_0000010

852438
type: Gene
SIO_000068: ncbigene

position:527025:-1
position: 527025
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:528038:-1
position: 528038
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:527025-528038:-1:exon

YBR141C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: BMT2
locus tag: YBR141C
product: 25S rRNA (adenine2142-N1)-methyltransferase
transcript id: NM_001178489.2
SIO_010081: YBR141C
subclass of: SO_0000673
so part of: YBR141C
location: complement(<527025..>528038)
location: region:527025-528038:-1
so has part: feature:527025-528038:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:527025-528038:-1:exon

YBR141C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: BMT2
locus tag: YBR141C
EC number: 2.1.1.286
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:23558746|PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0016433 rRNA (adenine) methyltransferase activity [PMID:23558746]
note: Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase; methylates adenine (m1A) of large subunit (LSU) rRNA at position 2142; belongs to Rossmann fold superfamily; null mutant exhibits abnormal lipid metabolic phenotype; not an essential gene
codon start: 1
product: 25S rRNA (adenine2142-N1)-methyltransferase
translation: MHSRKSKSITGKRKQVGSNVTRVIKPQKTRRIIRRFHHLINKRQSICKFLCLKENLDDSNEEKNDKIIRLSIKGNVRLGKYYEDGKSQSFNDAMESQLLRLHSLIKNESKSKDTSDLAVMYTLLGYIMNQINKLGGLETYQIASQNGQLKERGGDTSKLLEKWIRSSFENCPGAVALEIGSLSSGNRISRCALFRNVVRIDLEEHEGVIKQDFMERPLPRNENDKFDLISCSLVLNFVKNHRDRGAMCHRMVKFLKPQGYIFIVLPQACVTHSRYCDKTLLQNLLGSIGLIMLNSHQSNKLYYCLYQLQVVPPQPSSFSKRIKVNDGPGLNNFGITL
SIO_010081: YBR141C
subclass of: SO_0000673
so part of: YBR141C
location: complement(527025..528038)
location: region:527025-528038:-1
so has part: feature:527025-528038:-1:exon

NP_009699.2
type: Protein
SIO_000068: ncbiprotein

S000000345
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:527025-528038:-1:exon

YBR142W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MAK5
locus tag: YBR142W
so part of: sequence
location: <528317..>530638
location: region:528317-530638:1
so has part: feature:528317-530638:1:exon
subclass of: SO_0000010

852439
type: Gene
SIO_000068: ncbigene

position:528317:1
position: 528317
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:530638:1
position: 530638
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:528317-530638:1:exon

YBR142W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MAK5
locus tag: YBR142W
product: putative ATP-dependent RNA helicase
transcript id: NM_001178490.1
SIO_010081: YBR142W
subclass of: SO_0000673
so part of: YBR142W
location: <528317..>530638
location: region:528317-530638:1
so has part: feature:528317-530638:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:528317-530638:1:exon

YBR142W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MAK5
locus tag: YBR142W
EC number: 3.6.4.13
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:13680366]
experiment: EXISTENCE:mutant phenotype:GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:13680366]
experiment: EXISTENCE:mutant phenotype:GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:13680366]
experiment: EXISTENCE:mutant phenotype:GO:0042273 ribosomal large subunit biogenesis [PMID:13680366|PMID:7739558]
note: Essential nucleolar protein; putative DEAD-box RNA helicase required for maintenance of M1 dsRNA virus; involved in biogenesis of large (60S) ribosomal subunits
codon start: 1
product: putative ATP-dependent RNA helicase
translation: MGKKRAPQKGKTVTKPQEIIVDESKLNWKPVDIPDTLDDFGGFYGLEEIDGVDVKVVDGKVTFVTKKDSKVLKDSNKEKVGDDQESVENESGSDSESELLEFKNLDDIKEGELSAASYSSSDEDEQGNIESSKLTDPSEDVDEDVDEDVLKENVFNKDINIDDISPVNLPEWTNLAPLSMTILQSLQNLNFLRPTEIQKKSIPVIMQGVDVMGKASTGSGKTLAYGIPIVEKLISNFSQKNKKPISLIFTPTRELAHQVTDHLKKICEPVLAKSQYSILSLTGGLSIQKQQRLLKYDNSGQIVIATPGRFLELLEKDNTLIKRFSKVNTLILDEADRLLQDGHFDEFEKIIKHLLVERRKNRENSEGSSKIWQTLIFSATFSIDLFDKLSSSRQVKDRRFKNNEDELNAVIQHLMSKIHFNSKPVIIDTNPESKVSSQIKESLIECPPLERDLYCYYFLTMFPGTTLIFCNAIDSVKKLTVYLNNLGIPAFQIHSSMTQKNRLKSLERFKQQSAKQKTINHSNPDSVQLSTVLIASDVAARGLDIPGVQHVIHYHLPRSTDIYIHRSGRTARAGSEGVSAMICSPQESMGPLRKLRKTLATKNSVSTDLNSRSTNRKPIKWQNTVPLLPIETDILSQLRERSRLAGELADHEIASNSLRKDDNWLKKAADELGIDVDSDEDDISKSNSDTFLLKNKNKKMQKTINKDKVKAMRATLNELLSVPIRKDRRQKYLTGGLVNLADNLVKKRGHNSIIGHEKTNALETLKKKKKRNN
SIO_010081: YBR142W
subclass of: SO_0000673
so part of: YBR142W
location: 528317..530638
location: region:528317-530638:1
so has part: feature:528317-530638:1:exon

NP_009700.1
type: Protein
SIO_000068: ncbiprotein

S000000346
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:528317-530638:1:exon

YBR143C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SAL4
alternative label: SUP1
alternative label: SUP47
gene: SUP45
locus tag: YBR143C
gene synonym: SAL4; SUP1; SUP47
so part of: sequence
location: complement(<530869..>532182)
location: region:530869-532182:-1
so has part: feature:530869-532182:-1:exon
subclass of: SO_0000010

852440
type: Gene
SIO_000068: ncbigene

position:530869:-1
position: 530869
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:532182:-1
position: 532182
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:530869-532182:-1:exon

YBR143C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SAL4
alternative label: SUP1
alternative label: SUP47
gene: SUP45
locus tag: YBR143C
gene synonym: SAL4; SUP1; SUP47
product: translation termination factor eRF1
transcript id: NM_001178491.3
SIO_010081: YBR143C
subclass of: SO_0000673
so part of: YBR143C
location: complement(<530869..>532182)
location: region:530869-532182:-1
so has part: feature:530869-532182:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:530869-532182:-1:exon

YBR143C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SAL4
alternative label: SUP1
alternative label: SUP47
gene: SUP45
locus tag: YBR143C
gene synonym: SAL4; SUP1; SUP47
experiment: EXISTENCE:direct assay:GO:0003747 translation release factor activity [PMID:20947765]
experiment: EXISTENCE:direct assay:GO:0006415 translational termination [PMID:20947765]
experiment: EXISTENCE:direct assay:GO:0010494 cytoplasmic stress granule [PMID:23451152]
experiment: EXISTENCE:direct assay:GO:0018444 translation release factor complex [PMID:7556078]
experiment: EXISTENCE:genetic interaction:GO:0006415 translational termination [PMID:18724935]
experiment: EXISTENCE:mutant phenotype:GO:0006353 DNA-templated transcription termination [PMID:23109428]
experiment: EXISTENCE:mutant phenotype:GO:0006415 translational termination [PMID:9182990|PMID:18724935]
experiment: EXISTENCE:mutant phenotype:GO:0016149 translation release factor activity, codon specific [PMID:9182990]
note: Polypeptide release factor (eRF1) in translation termination; mutant form acts as a recessive omnipotent suppressor; methylated by Mtq2p-Trm112p in ternary complex eRF1-eRF3-GTP; mutation of methylation site confers resistance to zymocin; has a role in cytokinesis through interaction with Mlc1p
codon start: 1
product: translation termination factor eRF1
translation: MDNEVEKNIEIWKVKKLVQSLEKARGNGTSMISLVIPPKGQIPLYQKMLTDEYGTASNIKSRVNRLSVLSAITSTQQKLKLYNTLPKNGLVLYCGDIITEDGKEKKVTFDIEPYKPINTSLYLCDNKFHTEVLSELLQADDKFGFIVMDGQGTLFGSVSGNTRTVLHKFTVDLPKKHGRGGQSALRFARLREEKRHNYVRKVAEVAVQNFITNDKVNVKGLILAGSADFKTDLAKSELFDPRLACKVISIVDVSYGGENGFNQAIELSAEALANVKYVQEKKLLEAYFDEISQDTGKFCYGIDDTLKALDLGAVEKLIVFENLETIRYTFKDAEDNEVIKFAEPEAKDKSFAIDKATGQEMDVVSEEPLIEWLAANYKNFGATLEFITDKSSEGAQFVTGFGGIGAMLRYKVNFEQLVDESEDEYYDEDEGSDYDFI
SIO_010081: YBR143C
subclass of: SO_0000673
so part of: YBR143C
location: complement(530869..532182)
location: region:530869-532182:-1
so has part: feature:530869-532182:-1:exon

NP_009701.3
type: Protein
SIO_000068: ncbiprotein

S000000347
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:530869-532182:-1:exon

YBR144C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBR144C
so part of: sequence
location: complement(<533235..>533549)
location: region:533235-533549:-1
so has part: feature:533235-533549:-1:exon
subclass of: SO_0000010

852441
type: Gene
SIO_000068: ncbigene

position:533235:-1
position: 533235
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:533549:-1
position: 533549
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:533235-533549:-1:exon

YBR144C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBR144C
product: uncharacterized protein
transcript id: NM_001348890.1
SIO_010081: YBR144C
subclass of: SO_0000673
so part of: YBR144C
location: complement(<533235..>533549)
location: region:533235-533549:-1
so has part: feature:533235-533549:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:533235-533549:-1:exon

YBR144C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBR144C
note: hypothetical protein; conserved across S. cerevisiae strains; YBR144C is not an essential gene
codon start: 1
product: uncharacterized protein
translation: MLFDSSFRERRTFYNAAGSVSVPFYKQIAEQTHDIFKRCNVREHILRPCPVDISHFSRDLNGAPLSYTENIKFTAKFWANAWIDYESVMKTLLVKLYISFFFMC
SIO_010081: YBR144C
subclass of: SO_0000673
so part of: YBR144C
location: complement(533235..533549)
location: region:533235-533549:-1
so has part: feature:533235-533549:-1:exon

NP_001335745.1
type: Protein
SIO_000068: ncbiprotein

S000000348
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:533235-533549:-1:exon

YBR145W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ADH5
locus tag: YBR145W
so part of: sequence
location: <533762..>534817
location: region:533762-534817:1
so has part: feature:533762-534817:1:exon
subclass of: SO_0000010

852442
type: Gene
SIO_000068: ncbigene

position:533762:1
position: 533762
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:534817:1
position: 534817
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:533762-534817:1:exon

YBR145W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ADH5
locus tag: YBR145W
product: alcohol dehydrogenase ADH5
transcript id: NM_001178493.3
SIO_010081: YBR145W
subclass of: SO_0000673
so part of: YBR145W
location: <533762..>534817
location: region:533762-534817:1
so has part: feature:533762-534817:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:533762-534817:1:exon

YBR145W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ADH5
locus tag: YBR145W
EC number: 1.1.1.1
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:genetic interaction:GO:0000947 amino acid catabolic process to alcohol via Ehrlich pathway [PMID:12499363]
experiment: EXISTENCE:mutant phenotype:GO:0006116 NADH oxidation [PMID:15082781]
experiment: EXISTENCE:mutant phenotype:GO:0019655 glycolytic fermentation to ethanol [PMID:15082781]
note: Alcohol dehydrogenase isoenzyme V; involved in ethanol production; ADH5 has a paralog, ADH1, that arose from the whole genome duplication
codon start: 1
product: alcohol dehydrogenase ADH5
translation: MPSQVIPEKQKAIVFYETDGKLEYKDVTVPEPKPNEILVHVKYSGVCHSDLHAWHGDWPFQLKFPLIGGHEGAGVVVKLGSNVKGWKVGDFAGIKWLNGTCMSCEYCEVGNESQCPYLDGTGFTHDGTFQEYATADAVQAAHIPPNVNLAEVAPILCAGITVYKALKRANVIPGQWVTISGACGGLGSLAIQYALAMGYRVIGIDGGNAKRKLFEQLGGEIFIDFTEEKDIVGAIIKATNGGSHGVINVSVSEAAIEASTRYCRPNGTVVLVGMPAHAYCNSDVFNQVVKSISIVGSCVGNRADTREALDFFARGLIKSPIHLAGLSDVPEIFAKMEKGEIVGRYVVETSK
SIO_010081: YBR145W
subclass of: SO_0000673
so part of: YBR145W
location: 533762..534817
location: region:533762-534817:1
so has part: feature:533762-534817:1:exon

NP_009703.3
type: Protein
SIO_000068: ncbiprotein

S000000349
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:533762-534817:1:exon

YBR146W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: uS9m
gene: MRPS9
locus tag: YBR146W
gene synonym: uS9m
so part of: sequence
location: <535260..>536096
location: region:535260-536096:1
so has part: feature:535260-536096:1:exon
subclass of: SO_0000010

852443
type: Gene
SIO_000068: ncbigene

position:535260:1
position: 535260
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:536096:1
position: 536096
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:535260-536096:1:exon

YBR146W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: uS9m
gene: MRPS9
locus tag: YBR146W
gene synonym: uS9m
product: mitochondrial 37S ribosomal protein MRPS9
transcript id: NM_001178494.1
SIO_010081: YBR146W
subclass of: SO_0000673
so part of: YBR146W
location: <535260..>536096
location: region:535260-536096:1
so has part: feature:535260-536096:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:535260-536096:1:exon

YBR146W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: uS9m
gene: MRPS9
locus tag: YBR146W
gene synonym: uS9m
experiment: EXISTENCE:curator inference:GO:0032543 mitochondrial translation [PMID:11278769]
experiment: EXISTENCE:direct assay:GO:0003735 structural constituent of ribosome [PMID:11278769]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005763 mitochondrial small ribosomal subunit [PMID:11278769]
note: Mitochondrial ribosomal protein of the small subunit
codon start: 1
product: mitochondrial 37S ribosomal protein MRPS9
translation: MFSRLSLFRRAALAPAPMRMSFRTIYQKTEDELPRRIVPKLATFYSANPNHEDRINRLERLLRKYIKLPSQNNNEAQQTKAPWISFDEYALIGGGTKLKPTQYTQLLYMLNKLHNIDPQLTNDEITSELSQYYKKSSMLSNNIKIKTLDEFGRSIAVGKRKSSTAKVFVVRGTGEILVNGRQLNDYFLKMKDRESIMYPLQVIESVGKYNIFATTSGGGPTGQAESIMHAIAKALVVFNPLLKSRLHKAGVLTRDYRHVERKKPGKKKARKMPTWVKR
SIO_010081: YBR146W
subclass of: SO_0000673
so part of: YBR146W
location: 535260..536096
location: region:535260-536096:1
so has part: feature:535260-536096:1:exon

NP_009704.1
type: Protein
SIO_000068: ncbiprotein

S000000350
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:535260-536096:1:exon

YBR147W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RRT11
alternative label: YPQ3
gene: RTC2
locus tag: YBR147W
gene synonym: RRT11; YPQ3
so part of: sequence
location: <536575..>537465
location: region:536575-537465:1
so has part: feature:536575-537465:1:exon
subclass of: SO_0000010

852444
type: Gene
SIO_000068: ncbigene

position:536575:1
position: 536575
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:537465:1
position: 537465
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:536575-537465:1:exon

YBR147W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RRT11
alternative label: YPQ3
gene: RTC2
locus tag: YBR147W
gene synonym: RRT11; YPQ3
product: cationic amino acid transporter
transcript id: NM_001178495.1
SIO_010081: YBR147W
subclass of: SO_0000673
so part of: YBR147W
location: <536575..>537465
location: region:536575-537465:1
so has part: feature:536575-537465:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:536575-537465:1:exon

YBR147W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RRT11
alternative label: YPQ3
gene: RTC2
locus tag: YBR147W
gene synonym: RRT11; YPQ3
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:23169667]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961]
experiment: EXISTENCE:mutant phenotype:GO:0015174 basic amino acid transmembrane transporter activity [PMID:23169667]
experiment: EXISTENCE:mutant phenotype:GO:0034488 basic amino acid transmembrane export from vacuole [PMID:23169667]
note: Putative vacuolar membrane transporter for cationic amino acids; likely contributes to amino acid homeostasis by exporting cationic amino acids from the vacuole; positive regulation by Lys14p suggests that lysine may be the primary substrate; member of the PQ-loop family, with seven transmembrane domains; similar to mammalian PQLC2 vacuolar transporter; RTC2 has a paralog, YPQ1, that arose from the whole genome duplication
codon start: 1
product: cationic amino acid transporter
translation: MKLIPIILNAKNLSGMAGSISICCWIVVFVPQIYENFRRQSAEGLSLLFIVLWLLGDIFNVMGAMMQNLLPTMIILAAYYTLADLILLIQCMWYDKEKKSILQEVKKNVDPVHLPPANPINETVLQDVFNEYEPLLPRIEEEDSQSYSSLELGRTIVVKERENFFNDFLIVSGVLIAGILSWYISYCSGLDNGIPKKKPAFEQINLPAQILGYLSAILYLGSRIPQIVLNFKRKSCEGVSFLFFLFACLGNTSFIISVLSASWLIGSAGTLLMDFTVFIQFFLYAKPKYEKILIDN
SIO_010081: YBR147W
subclass of: SO_0000673
so part of: YBR147W
location: 536575..537465
location: region:536575-537465:1
so has part: feature:536575-537465:1:exon

NP_009705.1
type: Protein
SIO_000068: ncbiprotein

S000000351
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:536575-537465:1:exon

YBR148W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: YSW1
locus tag: YBR148W
so part of: sequence
location: <537876..>539705
location: region:537876-539705:1
so has part: feature:537876-539705:1:exon
subclass of: SO_0000010

852445
type: Gene
SIO_000068: ncbigene

position:537876:1
position: 537876
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:539705:1
position: 539705
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:537876-539705:1:exon

YBR148W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: YSW1
locus tag: YBR148W
product: Ysw1p
transcript id: NM_001178496.3
SIO_010081: YBR148W
subclass of: SO_0000673
so part of: YBR148W
location: <537876..>539705
location: region:537876-539705:1
so has part: feature:537876-539705:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:537876-539705:1:exon

YBR148W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: YSW1
locus tag: YBR148W
experiment: EXISTENCE:direct assay:GO:0005628 prospore membrane [PMID:19465564]
experiment: EXISTENCE:direct assay:GO:0031105 septin complex [PMID:24390141]
experiment: EXISTENCE:mutant phenotype:GO:0032120 ascospore-type prospore membrane formation [PMID:19465564]
note: Protein required for normal prospore membrane formation; interacts with Gip1p, which is the meiosis-specific regulatory subunit of the Glc7p protein phosphatase; expressed specifically in spores and localizes to the prospore membrane; YSW1 has a paralog, SPO21, that arose from the whole genome duplication
codon start: 1
product: Ysw1p
translation: MSSLADTVEGSEAKRGRFSNNALTSDTGILQKNSTLRNWFLKPTADLKNSCEDRVEDDVNDVYLNDKNSQKSVEERKLGRKVRSFFKQTNSNKDESVLEDEDDALVWKKTSNKCAKKENSHDIQKGSFTKKIRNSIFKSANDVKEFRNENNLLLPVELSSDDENESHFTDANSHVMQSKSPEKIPSKDQCLTKGAKNKGLKKEYEKSFEEYSDDSDDEFSPATPPENVLEGPYKFVFQTPNTFTSQPNITVENDFHKGGRHVIDYLNKKLATMNIDIDLTSGGKQNVSWEEELDQLSDHVIESITNHISKGRMHAQEKQDELEKLKLENLNLSTLKQENLQHKQEINSLKDNLESISKKNNDLILEMNKLKKKSTNNKTNEYISTDENENEEITKSNMGPGILELNVNETSKKLQQSTFKPSKYLPRETRNNENRLKHLEKRIFGLEKSLEKKKKQVRADSVRLDLNRYTIDQFLTLLKSLSEVLQFHNVYGNDLKENDDNIIKIETCCSALNMKNCFEDSSFRLQENSFKRQLGPLFANINFSLIDQLTMNFRFYERSANFQKETIGGLRMMLQDKDNYIKTLMQHLKKKESTKLIKDSKNGASTLTS
SIO_010081: YBR148W
subclass of: SO_0000673
so part of: YBR148W
location: 537876..539705
location: region:537876-539705:1
so has part: feature:537876-539705:1:exon

NP_009706.3
type: Protein
SIO_000068: ncbiprotein

S000000352
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:537876-539705:1:exon

YBR149W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ARA1
locus tag: YBR149W
so part of: sequence
location: <539987..>541021
location: region:539987-541021:1
so has part: feature:539987-541021:1:exon
subclass of: SO_0000010

852446
type: Gene
SIO_000068: ncbigene

position:539987:1
position: 539987
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:541021:1
position: 541021
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:539987-541021:1:exon

YBR149W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ARA1
locus tag: YBR149W
product: D-arabinose 1-dehydrogenase (NAD(P)(+)) ARA1
transcript id: NM_001178497.3
SIO_010081: YBR149W
subclass of: SO_0000673
so part of: YBR149W
location: <539987..>541021
location: region:539987-541021:1
so has part: feature:539987-541021:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:539987-541021:1:exon

YBR149W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ARA1
locus tag: YBR149W
EC number: 1.1.1.117
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:9920381]
experiment: EXISTENCE:direct assay:GO:0044262 cellular carbohydrate metabolic process [PMID:9920381]
experiment: EXISTENCE:direct assay:GO:0045290 D-arabinose 1-dehydrogenase [NAD(P)+] activity [PMID:9920381]
experiment: EXISTENCE:mutant phenotype:GO:0044262 cellular carbohydrate metabolic process [PMID:9920381]
note: NADP+ dependent arabinose dehydrogenase; involved in carbohydrate metabolism; purified as homodimer; naturally occurs with a N-terminus degradation product
codon start: 1
product: D-arabinose 1-dehydrogenase (NAD(P)(+)) ARA1
translation: MSSSVASTENIVENMLHPKTTEIYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELLEDGSIKREDLFITTKVWPVLWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPNLKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFASLTKDELQELNDFGEKYPVRFIDEPFAAILPEFTGNGPNLDNLKY
SIO_010081: YBR149W
subclass of: SO_0000673
so part of: YBR149W
location: 539987..541021
location: region:539987-541021:1
so has part: feature:539987-541021:1:exon

NP_009707.3
type: Protein
SIO_000068: ncbiprotein

S000000353
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:539987-541021:1:exon

YBR150C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TBS1
locus tag: YBR150C
so part of: sequence
location: complement(<541209..>544493)
location: region:541209-544493:-1
so has part: feature:541209-544493:-1:exon
subclass of: SO_0000010

852447
type: Gene
SIO_000068: ncbigene

position:541209:-1
position: 541209
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:544493:-1
position: 544493
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:541209-544493:-1:exon

YBR150C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TBS1
locus tag: YBR150C
product: Tbs1p
transcript id: NM_001178498.1
SIO_010081: YBR150C
subclass of: SO_0000673
so part of: YBR150C
location: complement(<541209..>544493)
location: region:541209-544493:-1
so has part: feature:541209-544493:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:541209-544493:-1:exon

YBR150C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TBS1
locus tag: YBR150C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:19158363]
note: hypothetical protein; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; associates with rDNA chromatin in vivo; TBS1 has a paralog, HAL9, that arose from the whole genome duplication
codon start: 1
product: Tbs1p
translation: MNMDSGITSSHGSMDKTQKQSSEWAANQKHNQRVENTRVLMGPAVPAMPPVPSNFPPVPTGTIMSPQLSPFPDHRLRHHPLAHMMPADKNFLAYNMESFKSRVTKACDYCRKRKIRCTEIEPISGKCRNCIKYNKDCTFHFHEELKRRREEALNNKGNGKSVKKPRLDKENKFKDENFDIAVRSRNTSSTDSSPKLHTNLSQEYIGVSAGKSASDKEDTWPDFVPIDRTVLEKIELNHTKVAGKVFVLEEICKNMKGTIEKLAEKSKIDVIDKEYMKRPKRKQYSKALLTKQKMFHFRQNVLSHLTDEEFLSPINEMFTTTFKYSILQTKLVLDFSFRSASSPSSDNILYPLPRLAIAKRLLKNIKCPSLASLLHIVDVDQCLQFADVHFDPAKGRLTSSQAFLLNICLCLGATVTNFEEKQELVDEDNHETYYFEKFELWRLRSFTFLNSVYYYHKLSVARADMTALKALLLLAKFAQQKISASSAVKVLSVAIKVALDLRLNLHSTYEDLELDEIIKRRRLWCYCFSTDKFFSVVLSRPPFLKEENTDVLTDESYVELFRDKILPNLSIKYDDSKLEGVKDIVSVVNLLANHLEYVPYIQSYFLSRLSLIESQIYYSCFSIRTTLDDTLDEIIENVLENQKALDRMRDDLPTILSLENYKENMRILSLDSSKLDFEVSCCTTILLHLRWYHQKITLSLFVISIIGDNLDQRESSRHDIAEIIRRSRLDFKRNCIEVLNILKDFEYYPTVQNEFLYFSLTTVFSMFLYLSEIMVNDEHAMETGYIIGLLRDTHTRMLGSEERCLSVHNLKWQTSLFFYTFFLRSTMEKFNLTSKYAKFYAFDSNYYEGVLNRLVKHTRESKDDMVELLKTSFINKEKMAAFGSFVTEDQEKMEVSFNIFNEITIQDLNFLQFSSIPKLWENKTLEPGEEYHHSNGTNTDNNETTGADDTDDNNNNNNNNNKNGNNSSSTINNNNNNYSNSNNNDNDNNINDDDDDDDDDDDDDDDDDDDDDNDDDYSNNGADDDEEDDDYDRSLFPTGLASLLDASYPERTANDYRDENEQSNKLFEKIEGHLEHGVFFYDRDFFFKNVCVKM
SIO_010081: YBR150C
subclass of: SO_0000673
so part of: YBR150C
location: complement(541209..544493)
location: region:541209-544493:-1
so has part: feature:541209-544493:-1:exon

NP_009708.1
type: Protein
SIO_000068: ncbiprotein

S000000354
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:541209-544493:-1:exon

YBR151W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: APD1
locus tag: YBR151W
so part of: sequence
location: <545028..>545978
location: region:545028-545978:1
so has part: feature:545028-545978:1:exon
subclass of: SO_0000010

852448
type: Gene
SIO_000068: ncbigene

position:545028:1
position: 545028
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:545978:1
position: 545978
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:545028-545978:1:exon

YBR151W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: APD1
locus tag: YBR151W
product: Apd1p
transcript id: NM_001178499.1
SIO_010081: YBR151W
subclass of: SO_0000673
so part of: YBR151W
location: <545028..>545978
location: region:545028-545978:1
so has part: feature:545028-545978:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:545028-545978:1:exon

YBR151W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: APD1
locus tag: YBR151W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:30879301]
note: 2Fe-2S cytosolic hypothetical protein; bishistidinyl coordinated, non-Rieske [2Fe-2S] cluster containing thiredoxin-like ferredoxin; required for normal localization of actin patches and for normal tolerance of sodium ions and hydrogen peroxide; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the cytoplasm; homologous to AIM32
codon start: 1
product: Apd1p
translation: MAFLNIFKQKRGDEASQLSAKGREEISQSIKICKSDDAANEHSCSGDCKTEIEEGEQAFAKLKIEHETPLLNSSKTPKIHFVVPTSQIDWQHDACLEDPKSVQYKISQWCDKNSAKFSNVGTGKTLNCAVSSLPKDIMDIDVMRGTKNNVLILPYFIWLNDLRSDDVEATLDGLVPDLLDENISREKLLETRPNVAVARERAFVFICSHTTRDKRCGITAPYLKKVFDSKLQEHGLYRDNSDYRAEGVKIAFVNHVGGHKFAANVQIYLRNPNTLIWLGRVTPTIVPSIVEHLIVPEEPTLPFPEKVRCIKKYQSW
SIO_010081: YBR151W
subclass of: SO_0000673
so part of: YBR151W
location: 545028..545978
location: region:545028-545978:1
so has part: feature:545028-545978:1:exon

NP_009709.1
type: Protein
SIO_000068: ncbiprotein

S000000355
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:545028-545978:1:exon

YBR152W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SPP381
locus tag: YBR152W
so part of: sequence
location: <546376..>547251
location: region:546376-547251:1
so has part: feature:546376-547251:1:exon
subclass of: SO_0000010

852449
type: Gene
SIO_000068: ncbigene

position:546376:1
position: 546376
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:547251:1
position: 547251
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:546376-547251:1:exon

YBR152W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SPP381
locus tag: YBR152W
product: U4/U6-U5 snRNP complex subunit SPP381
transcript id: NM_001178500.3
SIO_010081: YBR152W
subclass of: SO_0000673
so part of: YBR152W
location: <546376..>547251
location: region:546376-547251:1
so has part: feature:546376-547251:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:546376-547251:1:exon

YBR152W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SPP381
locus tag: YBR152W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0046540 U4/U6 x U5 tri-snRNP complex [PMID:9858581|PMID:10449419]
experiment: EXISTENCE:genetic interaction:GO:0000349 generation of catalytic spliceosome for first transesterification step [PMID:9858581]
experiment: EXISTENCE:mutant phenotype:GO:0000398 mRNA splicing, via spliceosome [PMID:9858581|PMID:10449419]
note: mRNA splicing factor, component of U4/U6.U5 tri-snRNP; interacts genetically and physically with Prp38p; relocalizes to the cytosol in response to hypoxia; temperature-sensitive phenotype of prp38-1 mutant can be suppressed by human homolog of SPP381, MFAP1
codon start: 1
product: U4/U6-U5 snRNP complex subunit SPP381
translation: MSFRHFKRRLDTSSADESSSADEEHPDQNVSLTEKSASLSHSDLGGEILNGTGKNRTPNDGQESNESDGSPESDESPESEESSDNSDSSDSDDMRPLPRPLFMKKKANNLQKATKIDQPWNAQDDARVLQTKKENMIKNIDKANQVAKNYETMKLRLNTNYSTNEELIKQCLLLDDNDEVDSEKERQKWFERQNERKQKHRRIQLAKQRESEEYEAKRFEAMQKGKDGNTKYDVILDKEKEKLDHKKQRSAEKVEKSHNNNRYKITRTKNVEFGDLGKNSRDYEETEYSVI
SIO_010081: YBR152W
subclass of: SO_0000673
so part of: YBR152W
location: 546376..547251
location: region:546376-547251:1
so has part: feature:546376-547251:1:exon

NP_009710.3
type: Protein
SIO_000068: ncbiprotein

S000000356
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:546376-547251:1:exon

YBR153W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RIB7
locus tag: YBR153W
so part of: sequence
location: <547460..>548194
location: region:547460-548194:1
so has part: feature:547460-548194:1:exon
subclass of: SO_0000010

852450
type: Gene
SIO_000068: ncbigene

position:547460:1
position: 547460
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:548194:1
position: 548194
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:547460-548194:1:exon

YBR153W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RIB7
locus tag: YBR153W
product: 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase
transcript id: NM_001178501.3
SIO_010081: YBR153W
subclass of: SO_0000673
so part of: YBR153W
location: <547460..>548194
location: region:547460-548194:1
so has part: feature:547460-548194:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:547460-548194:1:exon

YBR153W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RIB7
locus tag: YBR153W
EC number: 1.1.1.302
experiment: EXISTENCE:direct assay:GO:0008703 5-amino-6-(5-phosphoribosylamino)uracil reductase activity [PMID:23620735]
experiment: EXISTENCE:mutant phenotype:GO:0008703 5-amino-6-(5-phosphoribosylamino)uracil reductase activity [PMID:4555411]
experiment: EXISTENCE:mutant phenotype:GO:0009231 riboflavin biosynthetic process [PMID:5366000]
note: Diaminohydroxyphoshoribosylaminopyrimidine deaminase; catalyzes the second step of the riboflavin biosynthesis pathway
codon start: 1
product: 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase
translation: MSLTPLCEDLPQFLQNYLPNAGQTENTIVPFVTLTYAQSLDARVSRGPGVRTTISHPETKTMTHYLRHHHDGILVGSGTVLADNPGLNCKWGPDPAANSPRPIIIDTKQKWRFDGSKMQELFIKRQGKPPIVVVTSEPIIKEQHVDYAICPINDTTKLVDWKKLFEILKEEFNIRSVMVEGGANVINQLLLRSDIVNSLIITIGSTFLGSSGTEVSPPQTVNLKDMSWWKGITDVVLCARLADD
SIO_010081: YBR153W
subclass of: SO_0000673
so part of: YBR153W
location: 547460..548194
location: region:547460-548194:1
so has part: feature:547460-548194:1:exon

NP_009711.3
type: Protein
SIO_000068: ncbiprotein

S000000357
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:547460-548194:1:exon

YBR154C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: RPB5
locus tag: YBR154C
so part of: sequence
location: complement(<548362..>549009)
location: region:548362-549009:-1
so has part: feature:548362-549009:-1:exon
subclass of: SO_0000010

852451
type: Gene
SIO_000068: ncbigene

position:548362:-1
position: 548362
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:549009:-1
position: 549009
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:548362-549009:-1:exon

YBR154C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: RPB5
locus tag: YBR154C
product: DNA-directed RNA polymerase core subunit RPB5
transcript id: NM_001178502.1
SIO_010081: YBR154C
subclass of: SO_0000673
so part of: YBR154C
location: complement(<548362..>549009)
location: region:548362-549009:-1
so has part: feature:548362-549009:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:548362-549009:-1:exon

YBR154C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: RPB5
locus tag: YBR154C
experiment: EXISTENCE:direct assay:GO:0001054 RNA polymerase I activity [PMID:9837969]
experiment: EXISTENCE:direct assay:GO:0001055 RNA polymerase II activity [PMID:8288647]
experiment: EXISTENCE:direct assay:GO:0001056 RNA polymerase III activity [PMID:3905793]
experiment: EXISTENCE:direct assay:GO:0003968 RNA-dependent RNA polymerase activity [PMID:18004386]
experiment: EXISTENCE:direct assay:GO:0005665 RNA polymerase II, core complex [PMID:1331084|PMID:2183013|PMID:2186966]
experiment: EXISTENCE:direct assay:GO:0005666 RNA polymerase III complex [PMID:10611227|PMID:3905793]
experiment: EXISTENCE:direct assay:GO:0005736 RNA polymerase I complex [PMID:11486042|PMID:9837969]
experiment: EXISTENCE:direct assay:GO:0006360 transcription by RNA polymerase I [PMID:9837969]
experiment: EXISTENCE:direct assay:GO:0042797 tRNA transcription by RNA polymerase III [PMID:3905793]
experiment: EXISTENCE:genetic interaction:GO:0006366 transcription by RNA polymerase II [PMID:9860960]
experiment: EXISTENCE:mutant phenotype:GO:0006360 transcription by RNA polymerase I [PMID:17179178]
experiment: EXISTENCE:mutant phenotype:GO:0006366 transcription by RNA polymerase II [PMID:17179178|PMID:9860960]
experiment: EXISTENCE:mutant phenotype:GO:0006383 transcription by RNA polymerase III [PMID:17179178]
note: RNA polymerase subunit ABC27; common to RNA polymerases I, II, and III; contacts DNA and affects transactivation
codon start: 1
product: DNA-directed RNA polymerase core subunit RPB5
translation: MDQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
SIO_010081: YBR154C
subclass of: SO_0000673
so part of: YBR154C
location: complement(548362..549009)
location: region:548362-549009:-1
so has part: feature:548362-549009:-1:exon

NP_009712.1
type: Protein
SIO_000068: ncbiprotein

S000000358
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:548362-549009:-1:exon

misc_feature
type: Miscellaneous Feature
subclass of: SO_0000001
RO_0002162: 559292
note: ETC8; Chromosome-organizing-clamp; tethers chromosomal regions to the nuclear periphery; binds TFIIIC transcription factor but does not recruit RNA Polymerase III; can act as a transcription-blocking insulator or as a heterochromatin barrier element; located between divergently transcribed genes RPB5 and CNS1
so part of: sequence
location: 549229..549251
location: region:549229-549251:1
so has part: feature:549229-549251:1:region

S000077079
type: SGD
SIO_000068: sgd

position:549229:1
position: 549229
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:549251:1
position: 549251
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:549229-549251:1:region

YBR155W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CNS1
locus tag: YBR155W
so part of: sequence
location: <549771..>550928
location: region:549771-550928:1
so has part: feature:549771-550928:1:exon
subclass of: SO_0000010

852452
type: Gene
SIO_000068: ncbigene

position:549771:1
position: 549771
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:550928:1
position: 550928
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:549771-550928:1:exon

YBR155W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CNS1
locus tag: YBR155W
product: HSP70/90 family co-chaperone CNS1
transcript id: NM_001178503.1
SIO_010081: YBR155W
subclass of: SO_0000673
so part of: YBR155W
location: <549771..>550928
location: region:549771-550928:1
so has part: feature:549771-550928:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:549771-550928:1:exon

YBR155W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CNS1
locus tag: YBR155W
experiment: EXISTENCE:direct assay:GO:0030544 Hsp70 protein binding [PMID:15044454]
experiment: EXISTENCE:direct assay:GO:0043022 ribosome binding [PMID:25380751]
experiment: EXISTENCE:direct assay:GO:0051879 Hsp90 protein binding [PMID:12788914]
experiment: EXISTENCE:genetic interaction:GO:0042026 protein refolding [PMID:9819421]
experiment: EXISTENCE:physical interaction:GO:0005737 cytoplasm [PMID:15044454]
experiment: EXISTENCE:physical interaction:GO:0006457 protein folding [PMID:15044454]
note: TPR-containing co-chaperone; binds both Hsp82p (Hsp90) and Ssa1p (Hsp70); stimulates ATPase activity of Ssa1p; ts mutants reduce Hsp82p function, overexpression suppresses phenotypes of HSP82 ts allele and cpr7 deletion; human homolog TTC4 complements yeast cns1 mutant
codon start: 1
product: HSP70/90 family co-chaperone CNS1
translation: MSSVNANGGYTKPQKYVPGPGDPELPPQLSEFKDKTSDEILKEMNRMPFFMTKLDETDGAGGENVELEALKALAYEGEPHEIAENFKKQGNELYKAKRFKDARELYSKGLAVECEDKSINESLYANRAACELELKNYRRCIEDCSKALTINPKNVKCYYRTSKAFFQLNKLEEAKSAATFANQRIDPENKSILNMLSVIDRKEQELKAKEEKQQREAQERENKKIMLESAMTLRNITNIKTHSPVELLNEGKIRLEDPMDFESQLIYPALIMYPTQDEFDFVGEVSELTTVQELVDLVLEGPQERFKKEGKENFTPKKVLVFMETKAGGLIKAGKKLTFHDILKKESPDVPLFDNALKIYIVPKVESEGWISKWDKQKALERRSV
SIO_010081: YBR155W
subclass of: SO_0000673
so part of: YBR155W
location: 549771..550928
location: region:549771-550928:1
so has part: feature:549771-550928:1:exon

NP_009713.1
type: Protein
SIO_000068: ncbiprotein

S000000359
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:549771-550928:1:exon

YBR156C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SLI15
locus tag: YBR156C
so part of: sequence
location: complement(<551104..>553200)
location: region:551104-553200:-1
so has part: feature:551104-553200:-1:exon
subclass of: SO_0000010

852453
type: Gene
SIO_000068: ncbigene

position:551104:-1
position: 551104
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:553200:-1
position: 553200
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:551104-553200:-1:exon

YBR156C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SLI15
locus tag: YBR156C
product: Sli15p
transcript id: NM_001178504.3
SIO_010081: YBR156C
subclass of: SO_0000673
so part of: YBR156C
location: complement(<551104..>553200)
location: region:551104-553200:-1
so has part: feature:551104-553200:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:551104-553200:-1:exon

YBR156C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SLI15
locus tag: YBR156C
experiment: EXISTENCE:direct assay:GO:0005828 kinetochore microtubule [PMID:11724818]
experiment: EXISTENCE:direct assay:GO:0005876 spindle microtubule [PMID:11724818]
experiment: EXISTENCE:direct assay:GO:0032133 chromosome passenger complex [PMID:19158380]
experiment: EXISTENCE:direct assay:GO:0051233 spindle midzone [PMID:12566427]
experiment: EXISTENCE:mutant phenotype:GO:0007059 chromosome segregation [PMID:10385519]
experiment: EXISTENCE:mutant phenotype:GO:0030295 protein kinase activator activity [PMID:10385519]
experiment: EXISTENCE:mutant phenotype:GO:0032185 septin cytoskeleton organization [PMID:17652458]
experiment: EXISTENCE:mutant phenotype:GO:0032465 regulation of cytokinesis [PMID:16615892]
note: Subunit of the conserved chromosomal passenger complex (CPC); complex regulates kinetochore-microtubule attachments, activation of the spindle tension checkpoint, and mitotic spindle disassembly; other complex members are Ipl1p, Bir1p, and Nbl1p
codon start: 1
product: Sli15p
translation: MDWAIKAARKKTQRKPGSTRSIIETLDDLNNLTTDAHSEINQRLYESSEWLRNNVYMNTLKYEDKKMEESLISPENTHNKMDVEFPKMKGEYELSNSQNDAAKDVTKTPRNGLHNDKSITPKSLRRKEVTEGMNRFSIHDTNKSPVEPLNSVKVDANESEKSSPWSPYKVEKVLRESSKTSESPINTKRFDNQTWAAKEEMENEPILQALKKAESVKVKPPPNSGIARSQRRSNMFVPLPNKDPLIIQHIPPTKSSGSIPKVRTVKESPIAFKKKSTINSPAIRAVENSDTAGSTKASSVFDRLSSIPTKSFENKISRGNVGHKYSSSSIDLTGSPMKKVSQKFKSINSTDTDMQEALRDIFSVKNKITKNNSPKGKNSRKSSIPRFDKTSLKLTTHKKLAIIAEQKKKSKHSSDVHKTGSRPHSISPTKISVDSSSPSKEVKNYYQSPVRGYLRPTKASISPNKNKNLTTSQTPHRLKIKEKTLRKLSPNIADISKPESRKSKNYRLTNLQLLPPAEAERDDLKKKFDKRLSGIMRSQQEHHRRKQEKQKRMSHLEQDLKKQTSFSNDYKDIRLKESLAPFDNHVRDTINKNTAFSTDNILATINTVDHREIIGNVTPKIASVNDSLPEINTDSEDEASVTLAAWAKSPYLQEQLIRQQDINPQTIFGPIPPLHTDEIFPNPRLNRLKPRQIVPKRS
SIO_010081: YBR156C
subclass of: SO_0000673
so part of: YBR156C
location: complement(551104..553200)
location: region:551104-553200:-1
so has part: feature:551104-553200:-1:exon

NP_009714.3
type: Protein
SIO_000068: ncbiprotein

S000000360
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:551104-553200:-1:exon

YBR157C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ICS2
locus tag: YBR157C
so part of: sequence
location: complement(<553543..>554310)
location: region:553543-554310:-1
so has part: feature:553543-554310:-1:exon
subclass of: SO_0000010

852454
type: Gene
SIO_000068: ncbigene

position:553543:-1
position: 553543
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:554310:-1
position: 554310
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:553543-554310:-1:exon

YBR157C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ICS2
locus tag: YBR157C
product: Ics2p
transcript id: NM_001178505.3
SIO_010081: YBR157C
subclass of: SO_0000673
so part of: YBR157C
location: complement(<553543..>554310)
location: region:553543-554310:-1
so has part: feature:553543-554310:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:553543-554310:-1:exon

YBR157C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ICS2
locus tag: YBR157C
note: hypothetical protein; null mutation does not confer any obvious defects in growth, spore germination, viability, or carbohydrate utilization
codon start: 1
product: Ics2p
translation: MGKFEQKERERISTFSFPTTGSQSSTSIKSLGSPLYGRFSSLSSTESQFDSSKQPHEYEKSFYFEESQGEALFNKLKTYSFPGDKDGVKTRRNSSICPRKPNAVSPLRVESNELSSHSHSRSLSHELTKPSGRRKSYHRKSHAISFSRSCKPNFIDGYDSNSSIGVNSRKTSLASSFLDKEYHSSPDTSYTHQMSPKNTIMNTNEQLRRNASGRFGSLKEFAEKNQINIEGKIFAHKVETGDILQPLIDLDIDNK
SIO_010081: YBR157C
subclass of: SO_0000673
so part of: YBR157C
location: complement(553543..554310)
location: region:553543-554310:-1
so has part: feature:553543-554310:-1:exon

NP_009715.4
type: Protein
SIO_000068: ncbiprotein

S000000361
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:553543-554310:-1:exon

YBR158W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CST13
alternative label: ICS4
gene: AMN1
locus tag: YBR158W
gene synonym: CST13; ICS4
so part of: sequence
location: <556549..>558198
location: region:556549-558198:1
so has part: feature:556549-558198:1:exon
subclass of: SO_0000010

852455
type: Gene
SIO_000068: ncbigene

position:556549:1
position: 556549
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:558198:1
position: 558198
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:556549-558198:1:exon

YBR158W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CST13
alternative label: ICS4
gene: AMN1
locus tag: YBR158W
gene synonym: CST13; ICS4
product: Amn1p
transcript id: NM_001178506.1
SIO_010081: YBR158W
subclass of: SO_0000673
so part of: YBR158W
location: <556549..>558198
location: region:556549-558198:1
so has part: feature:556549-558198:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:556549-558198:1:exon

YBR158W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CST13
alternative label: ICS4
gene: AMN1
locus tag: YBR158W
gene synonym: CST13; ICS4
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:12628189]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:12628189]
experiment: EXISTENCE:direct assay:GO:0005933 cellular bud [PMID:12628189]
experiment: EXISTENCE:genetic interaction:GO:0001100 negative regulation of exit from mitosis [PMID:12628189]
experiment: EXISTENCE:genetic interaction:GO:2001042 negative regulation of septum digestion after cytokinesis [PMID:30273335]
experiment: EXISTENCE:mutant phenotype:GO:0001100 negative regulation of exit from mitosis [PMID:12628189]
experiment: EXISTENCE:mutant phenotype:GO:0007094 mitotic spindle assembly checkpoint signaling [PMID:12628189]
experiment: EXISTENCE:mutant phenotype:GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [PMID:30273335]
experiment: EXISTENCE:mutant phenotype:GO:0031578 mitotic spindle orientation checkpoint signaling [PMID:12628189]
experiment: EXISTENCE:mutant phenotype:GO:0032984 protein-containing complex disassembly [PMID:12628189]
experiment: EXISTENCE:mutant phenotype:GO:2001042 negative regulation of septum digestion after cytokinesis [PMID:30273335]
experiment: EXISTENCE:physical interaction:GO:0031267 small GTPase binding [PMID:12628189]
note: Modulator of cell separation and mitotic exit; inhibits separation through Ub-dependent Ace2p proteolysis; part of a daughter-specific switch induced by the mitotic exit network that inhibits exit and resets the cell cycle after the execution of MEN function, blocking Tem1p and Cdc15 association; required for chromosome stability and multiple mitotic checkpoints; regulated by SCF; haploid transcription regulated by Ste12p; contains 12 degenerate leucine-rich repeat motifs and an atypical F-box
codon start: 1
product: Amn1p
translation: MKLERVSSNGSFKRGRDIQSLESPCTRPLKKMSPSPSFTSLKMEKPFKDIVRKYGGHLHQSSYNPGSSKVELVRPDLSLKTDQSFLQSSVQTTPNKKSCNEYLSTPEATPLKNTATENAWATSRVVSASSLSIVTPTEIKNILVDEFSELKLGQPLTAQHQRSHAVFEIPEIVENIIKMIVSLESANIPKERPCLRRNPQSYEHSLLMYKDEERAKKAWSAAQQLRDPPLVGHKEKKQGALFSCMMVNRLWLNVTRPFLFKSLHFKSVHNFKEFLRTSQETTQVMRPSHFILHKLHQVTQPDIERLSRMECQNLKWLEFYVCPRITPPLSWFDNLHKLEKLIIPGNKNIDDNFLLRLSQSIPNLKHLVLRACDNVSDSGVVCIALNCPKLKTFNIGRHRRGNLITSVSLVALGKYTQVETVGFAGCDVDDAGIWEFARLNGKNVERLSLNSCRLLTDYSLPILFALNSFPNLAVLEIRNLDKITDVRHFVKYNLWKKSLDAPILIEACERITKLIDQEENRVKRINSLVALKDMTAWVNADDEIENNVD
SIO_010081: YBR158W
subclass of: SO_0000673
so part of: YBR158W
location: 556549..558198
location: region:556549-558198:1
so has part: feature:556549-558198:1:exon

NP_009716.1
type: Protein
SIO_000068: ncbiprotein

S000000362
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:556549-558198:1:exon

YBR159W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: IFA38
locus tag: YBR159W
so part of: sequence
location: <558685..>559728
location: region:558685-559728:1
so has part: feature:558685-559728:1:exon
subclass of: SO_0000010

852456
type: Gene
SIO_000068: ncbigene

position:558685:1
position: 558685
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:559728:1
position: 559728
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:558685-559728:1:exon

YBR159W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: IFA38
locus tag: YBR159W
product: ketoreductase
transcript id: NM_001178507.1
SIO_010081: YBR159W
subclass of: SO_0000673
so part of: YBR159W
location: <558685..>559728
location: region:558685-559728:1
so has part: feature:558685-559728:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:558685-559728:1:exon

YBR159W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: IFA38
locus tag: YBR159W
EC number: 1.1.1.330
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:12087109]
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:23263984]
experiment: EXISTENCE:mutant phenotype:GO:0030148 sphingolipid biosynthetic process [PMID:23263984]
experiment: EXISTENCE:mutant phenotype:GO:0030497 fatty acid elongation [PMID:12087109]
experiment: EXISTENCE:mutant phenotype:GO:0042761 very long-chain fatty acid biosynthetic process [PMID:23263984]
experiment: EXISTENCE:mutant phenotype:GO:0045703 ketoreductase activity [PMID:12087109]
note: Microsomal beta-keto-reductase; contains oleate response element (ORE) sequence in the promoter region; mutants exhibit reduced VLCFA synthesis, accumulate high levels of dihydrosphingosine, phytosphingosine and medium-chain ceramides
codon start: 1
product: ketoreductase
translation: MTFMQQLQEAGERFRCINGLLWVVFGLGVLKCTTLSLRFLALIFDLFLLPAVNFDKYGAKTGKYCAITGASDGIGKEFARQMAKRGFNLVLISRTQSKLEALQKELEDQHHVVVKILAIDIAEDKESNYESIKELCAQLPITVLVNNVGQSHSIPVPFLETEEKELRNIITINNTATLLITQIIAPKIVETVKAENKKSGTRGLILTMGSFGGLIPTPLLATYSGSKSFLQGWSNSLAGELSKDAIDVELIISYLVTSSMSKIRRSSLMIPNPQQFVKSTLRSVGRRCGSQERYATMTPYWAHAVYQFVITETFGVYSKIVNSINYSFHKSIRIRALKKAARQVKKE
SIO_010081: YBR159W
subclass of: SO_0000673
so part of: YBR159W
location: 558685..559728
location: region:558685-559728:1
so has part: feature:558685-559728:1:exon

NP_009717.1
type: Protein
SIO_000068: ncbiprotein

S000000363
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:558685-559728:1:exon

YBR160W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CDK1
alternative label: HSL5
alternative label: SRM5
gene: CDC28
locus tag: YBR160W
gene synonym: CDK1; HSL5; SRM5
so part of: sequence
location: <560078..>560974
location: region:560078-560974:1
so has part: feature:560078-560974:1:exon
subclass of: SO_0000010

852457
type: Gene
SIO_000068: ncbigene

position:560078:1
position: 560078
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:560974:1
position: 560974
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:560078-560974:1:exon

YBR160W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CDK1
alternative label: HSL5
alternative label: SRM5
gene: CDC28
locus tag: YBR160W
gene synonym: CDK1; HSL5; SRM5
product: cyclin-dependent serine/threonine-protein kinase CDC28
transcript id: NM_001178508.3
SIO_010081: YBR160W
subclass of: SO_0000673
so part of: YBR160W
location: <560078..>560974
location: region:560078-560974:1
so has part: feature:560078-560974:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:560078-560974:1:exon

YBR160W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CDK1
alternative label: HSL5
alternative label: SRM5
gene: CDC28
locus tag: YBR160W
gene synonym: CDK1; HSL5; SRM5
EC number: 2.7.11.22
experiment: EXISTENCE:direct assay:GO:0000307 cyclin-dependent protein kinase holoenzyme complex [PMID:1849458|PMID:2142620]
experiment: EXISTENCE:direct assay:GO:0000723 telomere maintenance [PMID:24164896]
experiment: EXISTENCE:direct assay:GO:0000993 RNA polymerase II complex binding [PMID:22689984]
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:16319894]
experiment: EXISTENCE:direct assay:GO:0004674 protein serine/threonine kinase activity [PMID:16096060|PMID:22521784|PMID:22563681|PMID:22689984|P MID:23314252|PMID:24319056|PMID:27203178|PMID:21498574|PMI D:12050115|PMID:25602519|PMID:32083180|PMID:8930895]
experiment: EXISTENCE:direct assay:GO:0004693 cyclin-dependent protein serine/threonine kinase activity [PMID:2142620|PMID:27068241]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14685274]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:3312233]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:17560371]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:12554645]
experiment: EXISTENCE:direct assay:GO:0010494 cytoplasmic stress granule [PMID:26777405]
experiment: EXISTENCE:direct assay:GO:0010571 positive regulation of nuclear cell cycle DNA replication [PMID:14747467]
experiment: EXISTENCE:direct assay:GO:0042393 histone binding [PMID:20855529]
experiment: EXISTENCE:direct assay:GO:0045892 negative regulation of DNA-templated transcription [PMID:14993267]
experiment: EXISTENCE:direct assay:GO:0045893 positive regulation of DNA-templated transcription [PMID:1652372]
experiment: EXISTENCE:direct assay:GO:0045930 negative regulation of mitotic cell cycle [PMID:10074450]
experiment: EXISTENCE:direct assay:GO:0051446 positive regulation of meiotic cell cycle [PMID:16814718]
experiment: EXISTENCE:direct assay:GO:1905634 regulation of protein localization to chromatin [PMID:25602519]
experiment: EXISTENCE:genetic interaction:GO:0000706 meiotic DNA double-strand break processing [PMID:20150422]
experiment: EXISTENCE:genetic interaction:GO:0010568 regulation of budding cell apical bud growth [PMID:17417630]
experiment: EXISTENCE:genetic interaction:GO:0010696 positive regulation of mitotic spindle pole body separation [PMID:16688214]
experiment: EXISTENCE:genetic interaction:GO:0010898 positive regulation of triglyceride catabolic process [PMID:19150427]
experiment: EXISTENCE:genetic interaction:GO:0030163 protein catabolic process [PMID:21993622]
experiment: EXISTENCE:genetic interaction:GO:0032210 regulation of telomere maintenance via telomerase [PMID:19135888]
experiment: EXISTENCE:genetic interaction:GO:0045893 positive regulation of DNA-templated transcription [PMID:1652372]
experiment: EXISTENCE:genetic interaction:GO:0090307 mitotic spindle assembly [PMID:21558801]
experiment: EXISTENCE:genetic interaction:GO:1901319 positive regulation of trehalose catabolic process [PMID:27203179]
experiment: EXISTENCE:genetic interaction:GO:1902596 negative regulation of DNA replication origin binding [PMID:29388912]
experiment: EXISTENCE:genetic interaction:GO:1990758 mitotic sister chromatid biorientation [PMID:22056777]
experiment: EXISTENCE:mutant phenotype:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:22056777]
experiment: EXISTENCE:mutant phenotype:GO:0000729 DNA double-strand break processing [PMID:21841787]
experiment: EXISTENCE:mutant phenotype:GO:0004674 protein serine/threonine kinase activity [PMID:22521784|PMID:21841787|PMID:8930895]
experiment: EXISTENCE:mutant phenotype:GO:0006303 double-strand break repair via nonhomologous end joining [PMID:22563681]
experiment: EXISTENCE:mutant phenotype:GO:0006370 7-methylguanosine mRNA capping [PMID:22689984]
experiment: EXISTENCE:mutant phenotype:GO:0006892 post-Golgi vesicle-mediated transport [PMID:22767578]
experiment: EXISTENCE:mutant phenotype:GO:0007130 synaptonemal complex assembly [PMID:20825495]
experiment: EXISTENCE:mutant phenotype:GO:0010568 regulation of budding cell apical bud growth [PMID:17417630]
experiment: EXISTENCE:mutant phenotype:GO:0010570 regulation of filamentous growth [PMID:9891070]
experiment: EXISTENCE:mutant phenotype:GO:0010571 positive regulation of nuclear cell cycle DNA replication [PMID:12783856|PMID:14747467|PMID:4580573]
experiment: EXISTENCE:mutant phenotype:GO:0010696 positive regulation of mitotic spindle pole body separation [PMID:16688214|PMID:8887667]
experiment: EXISTENCE:mutant phenotype:GO:0010898 positive regulation of triglyceride catabolic process [PMID:19150427]
experiment: EXISTENCE:mutant phenotype:GO:0030163 protein catabolic process [PMID:21098119]
experiment: EXISTENCE:mutant phenotype:GO:0032880 regulation of protein localization [PMID:29263158]
experiment: EXISTENCE:mutant phenotype:GO:0034504 protein localization to nucleus [PMID:19188495]
experiment: EXISTENCE:mutant phenotype:GO:0045819 positive regulation of glycogen catabolic process [PMID:27203179]
experiment: EXISTENCE:mutant phenotype:GO:0045875 negative regulation of sister chromatid cohesion [PMID:21549314]
experiment: EXISTENCE:mutant phenotype:GO:0045892 negative regulation of DNA-templated transcription [PMID:12081645|PMID:14993267]
experiment: EXISTENCE:mutant phenotype:GO:0045931 positive regulation of mitotic cell cycle [PMID:2165600|PMID:7002718]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:22689984]
experiment: EXISTENCE:mutant phenotype:GO:0051446 positive regulation of meiotic cell cycle [PMID:16814718|PMID:2680756]
experiment: EXISTENCE:mutant phenotype:GO:0051447 negative regulation of meiotic cell cycle [PMID:12081645]
experiment: EXISTENCE:mutant phenotype:GO:0090169 regulation of spindle assembly [PMID:21558801]
experiment: EXISTENCE:mutant phenotype:GO:1901319 positive regulation of trehalose catabolic process [PMID:27203179]
experiment: EXISTENCE:mutant phenotype:GO:1902889 protein localization to spindle microtubule [PMID:22521784]
experiment: EXISTENCE:mutant phenotype:GO:1903500 negative regulation of mitotic actomyosin contractile ring assembly [PMID:24413167]
experiment: EXISTENCE:mutant phenotype:GO:1904291 positive regulation of mitotic DNA damage checkpoint [PMID:15496928]
experiment: EXISTENCE:mutant phenotype:GO:1905168 positive regulation of double-strand break repair via homologous recombination [PMID:15496928]
experiment: EXISTENCE:mutant phenotype:GO:1990139 protein localization to nuclear periphery [PMID:20702586]
experiment: EXISTENCE:mutant phenotype:GO:2001033 negative regulation of double-strand break repair via nonhomologous end joining [PMID:19699692]
note: Cyclin-dependent kinase (CDK) catalytic subunit; master regulator of mitotic and meiotic cell cycles; alternately associates with G1, S, G2/M phase cyclins, which provide substrate specificity; regulates metabolism, basal transcription, chromosome dynamics, growth and morphogenesis; transcript induction in osmostress involves antisense RNA; human homologs CDK1, CDK2, CDK3 can complement yeast conditional cdc28 mutants; human CDK1, CDK2 can complement yeast cdc28 null mutant
codon start: 1
product: cyclin-dependent serine/threonine-protein kinase CDC28
translation: MSGELANYKRLEKVGEGTYGVVYKALDLRPGQGQRVVALKKIRLESEDEGVPSTAIREISLLKELKDDNIVRLYDIVHSDAHKLYLVFEFLDLDLKRYMEGIPKDQPLGADIVKKFMMQLCKGIAYCHSHRILHRDLKPQNLLINKDGNLKLGDFGLARAFGVPLRAYTHEIVTLWYRAPEVLLGGKQYSTGVDTWSIGCIFAEMCNRKPIFSGDSEIDQIFKIFRVLGTPNEAIWPDIVYLPDFKPSFPQWRRKDLSQVVPSLDPRGIDLLDKLLAYDPINRISARRAAIHPYFQES
SIO_010081: YBR160W
subclass of: SO_0000673
so part of: YBR160W
location: 560078..560974
location: region:560078-560974:1
so has part: feature:560078-560974:1:exon

NP_009718.3
type: Protein
SIO_000068: ncbiprotein

S000000364
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:560078-560974:1:exon

YBR161W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CSH1
locus tag: YBR161W
so part of: sequence
location: <561634..>562764
location: region:561634-562764:1
so has part: feature:561634-562764:1:exon
subclass of: SO_0000010

852458
type: Gene
SIO_000068: ncbigene

position:561634:1
position: 561634
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:562764:1
position: 562764
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:561634-562764:1:exon

YBR161W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CSH1
locus tag: YBR161W
product: mannosylinositol phosphorylceramide synthase catalytic subunit CSH1
transcript id: NM_001178509.3
SIO_010081: YBR161W
subclass of: SO_0000673
so part of: YBR161W
location: <561634..>562764
location: region:561634-562764:1
so has part: feature:561634-562764:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:561634-562764:1:exon

YBR161W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CSH1
locus tag: YBR161W
EC number: 2.4.1.370
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:14562095|PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0006688 glycosphingolipid biosynthetic process [PMID:12954640]
experiment: EXISTENCE:mutant phenotype:GO:0030148 sphingolipid biosynthetic process [PMID:12954640]
experiment: EXISTENCE:mutant phenotype:GO:0103064 inositol phosphorylceramide mannosyltransferase activity [PMID:12954640]
note: Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit; forms a complex with regulatory subunit Csg2p; function in sphingolipid biosynthesis is overlapping with that of Sur1p; CSH1 has a paralog, SUR1, that arose from the whole genome duplication
codon start: 1
product: mannosylinositol phosphorylceramide synthase catalytic subunit CSH1
translation: MKKELKILIIANIALLISIIHYTFDLLTLCIDDTSKDALTDEQLNPPNGFNSTFYESPPQLIPKIIHQTYKTNDIPEQWVKGRQKCIDLHPDYTYILWTDEMSDTFIKQEYPWFLDTFRSYEYPIERADAIRYFILSHYGGIYIDLDDGCERRLDPLLKVPAFLRKTSPTGVSNDVMGSVPRHPFFLKVIKSLKHYKKNWYIPYMTIMGSTGPLFISVVWKQYKRWSNTAENGAVRILQPADYKMHNNSFFSISKGSSWHTGDANFMKTLENHILSCVVTGFIFGFFILYGEFTFYTWLCSGPFNNKRYYIQWLSDKFKLHKWKLTSSYKNKEKRRNPTRHEYNSRGKRLRKDSNIPYDSVFLDIEKNHAKFTDLT
SIO_010081: YBR161W
subclass of: SO_0000673
so part of: YBR161W
location: 561634..562764
location: region:561634-562764:1
so has part: feature:561634-562764:1:exon

NP_009719.3
type: Protein
SIO_000068: ncbiprotein

S000000365
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:561634-562764:1:exon

YBR162C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TOS1
locus tag: YBR162C
so part of: sequence
location: complement(<563203..>564570)
location: region:563203-564570:-1
so has part: feature:563203-564570:-1:exon
subclass of: SO_0000010

852459
type: Gene
SIO_000068: ncbigene

position:563203:-1
position: 563203
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:564570:-1
position: 564570
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:563203-564570:-1:exon

YBR162C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TOS1
locus tag: YBR162C
product: Tos1p
transcript id: NM_001178510.1
SIO_010081: YBR162C
subclass of: SO_0000673
so part of: YBR162C
location: complement(<563203..>564570)
location: region:563203-564570:-1
so has part: feature:563203-564570:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:563203-564570:-1:exon

YBR162C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TOS1
locus tag: YBR162C
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0009277 fungal-type cell wall [PMID:11935221|PMID:15781460]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
note: Covalently-bound cell wall hypothetical protein; identified as a cell cycle regulated SBF target gene; deletion mutants are highly resistant to treatment with beta-1,3-glucanase; has sequence similarity to YJL171C
codon start: 1
product: Tos1p
translation: MLQKLSMTALVGLFSSVVSLVNADCTYSGGNYYCAQTDAIIYSNVGLSATYQDVTNMDESSCACTQADFTASGSLAPFNEELSVHFRGPIELLQFGVYYPNGESNALKKRSEKQSIESCKEGEAVVSRHKHQHKRDVAVEYVQVTSTVYVDSNGQTVTADSTNTVVGPAVPSSYTKDSTVLSSSAQAVETSESQSSISSSKTTSSAAAASSSSSSSSNTNGDWSRGSYFVPGSTSNCTFMNNQGGTAGSGVWSSCFGNSISFAASDGVSGAASAQALGDVTIKSGNEFMIFSGEECSGNNGDCGYYREGIPAYHGFGGADKIFVFEFSMPSDTSGSAYNQDMPAIWLLNAKIPRTLQYGDASCSCWKTGCGEMDLFEILTAGSDKLISHIHDGQDGGTQDYFERPTDGTLKAAVIFNSSDKTIHIIEVDESFDATLSDDVVDQWLSKSGSSAALP
SIO_010081: YBR162C
subclass of: SO_0000673
so part of: YBR162C
location: complement(563203..564570)
location: region:563203-564570:-1
so has part: feature:563203-564570:-1:exon

NP_009720.1
type: Protein
SIO_000068: ncbiprotein

S000000366
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:563203-564570:-1:exon

YBR162W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: YSY6
locus tag: YBR162W-A
so part of: sequence
location: <565231..>565428
location: region:565231-565428:1
so has part: feature:565231-565428:1:exon
subclass of: SO_0000010

852460
type: Gene
SIO_000068: ncbigene

position:565231:1
position: 565231
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:565428:1
position: 565428
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:565231-565428:1:exon

YBR162W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: YSY6
locus tag: YBR162W-A
product: Ysy6p
transcript id: NM_001180059.1
SIO_010081: YBR162W-A
subclass of: SO_0000673
so part of: YBR162W-A
location: <565231..>565428
location: region:565231-565428:1
so has part: feature:565231-565428:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:565231-565428:1:exon

YBR162W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: YSY6
locus tag: YBR162W-A
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:14562095|PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0009306 protein secretion [PMID:10469658]
note: hypothetical protein; expression suppresses a secretory pathway mutation in E. coli; has similarity to the mammalian RAMP4 protein involved in secretion
codon start: 1
product: Ysy6p
translation: MAVQTPRQRLANAKFNKNNEKYRKYGKKKEGKTEKTAPVISKTWLGILLFLLVGGGVLQLISYIL
SIO_010081: YBR162W-A
subclass of: SO_0000673
so part of: YBR162W-A
location: 565231..565428
location: region:565231-565428:1
so has part: feature:565231-565428:1:exon

NP_009721.1
type: Protein
SIO_000068: ncbiprotein

S000002158
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:565231-565428:1:exon

YBR163W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: DEM1
gene: EXO5
locus tag: YBR163W
gene synonym: DEM1
so part of: sequence
location: <565723..>567480
location: region:565723-567480:1
so has part: feature:565723-567480:1:exon
subclass of: SO_0000010

852461
type: Gene
SIO_000068: ncbigene

position:565723:1
position: 565723
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:567480:1
position: 567480
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:565723-567480:1:exon

YBR163W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: DEM1
gene: EXO5
locus tag: YBR163W
gene synonym: DEM1
product: Exo5p
transcript id: NM_001178511.3
SIO_010081: YBR163W
subclass of: SO_0000673
so part of: YBR163W
location: <565723..>567480
location: region:565723-567480:1
so has part: feature:565723-567480:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:565723-567480:1:exon

YBR163W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: DEM1
gene: EXO5
locus tag: YBR163W
gene synonym: DEM1
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity [PMID:20086101]
experiment: EXISTENCE:mutant phenotype:GO:0000002 mitochondrial genome maintenance [PMID:20086101]
note: Mitochondrial 5'-3' exonuclease and sliding exonuclease; required for mitochondrial genome maintenance; distantly related to the RecB nuclease domain of bacterial RecBCD recombinases; may be regulated by the transcription factor Ace2
codon start: 1
product: Exo5p
translation: MLGRALINKYGFLIHPRRFVHLNDKSLDGTFILPSKKNHMYDVPTNDPSGILNASDIDRINNLPFFDNTSPTKETNTKEGALLSEKLASVKELFGEDPENPSFINYRFPRGLENPYFDIQVNQLKKKRLSVTQLCTTQNWCELRNFYDFYSQNLSNQLLNLKFQVQKGKKIHKSLEDETHPELNQYKSFTHNFLALTKLSMDIDNDMDALLDNWFNSINRLVSLFTKGDGHAREIVCHGFINLEDGKLVEHLLNSDSKTKENVIISGVIDHLTLRNRHNHQVQKGAAHLDTEYQSWGNILTNLLSNLKELKSNNEIVISDIKTRSVPKIPSIESVIESSKLQTMYYKFFFSHLSQDMTQTYHSFLINAQRRGLDVDAPINPTKILTFILTNPLFANDVKNLLYGLPINHSAFDNDAKGSNTFDMTAFNDLLDRGPTSFNVPIEQDEDSSESTKCVSLRDYGHFYTKWKTPLTLKYFAARLSQIYFIVGNLVSNDLMIEYYYHNDNFHNIIFPYDPLKLGTHAHDSAMVWFGGRDMHPIEPTQKNFNTYCKFCDYRHVCSWKNKNELKLIDLGKELKKIILESSMK
SIO_010081: YBR163W
subclass of: SO_0000673
so part of: YBR163W
location: 565723..567480
location: region:565723-567480:1
so has part: feature:565723-567480:1:exon

NP_009722.3
type: Protein
SIO_000068: ncbiprotein

S000000367
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:565723-567480:1:exon

YBR164C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: DLP2
gene: ARL1
locus tag: YBR164C
gene synonym: DLP2
so part of: sequence
location: complement(<567875..>568426)
location: region:567875-568426:-1
so has part: feature:567875-568426:-1:exon
subclass of: SO_0000010

852462
type: Gene
SIO_000068: ncbigene

position:567875:-1
position: 567875
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:568426:-1
position: 568426
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:567875-568426:-1:exon

YBR164C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: DLP2
gene: ARL1
locus tag: YBR164C
gene synonym: DLP2
product: Arf family GTPase ARL1
transcript id: NM_001178512.3
SIO_010081: YBR164C
subclass of: SO_0000673
so part of: YBR164C
location: complement(<567875..>568426)
location: region:567875-568426:-1
so has part: feature:567875-568426:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:567875-568426:-1:exon

YBR164C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: DLP2
gene: ARL1
locus tag: YBR164C
gene synonym: DLP2
experiment: EXISTENCE:direct assay:GO:0003924 GTPase activity [PMID:9388248]
experiment: EXISTENCE:direct assay:GO:0005794 Golgi apparatus [PMID:15077113|PMID:15564045]
experiment: EXISTENCE:direct assay:GO:0005802 trans-Golgi network [PMID:15975906|PMID:23345439]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:15975906|PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0016236 macroautophagy [PMID:27462928]
experiment: EXISTENCE:mutant phenotype:GO:0006623 protein targeting to vacuole [PMID:12052896|PMID:12210899]
experiment: EXISTENCE:mutant phenotype:GO:0006897 endocytosis [PMID:12052896]
experiment: EXISTENCE:mutant phenotype:GO:0016192 vesicle-mediated transport [PMID:11840166]
experiment: EXISTENCE:mutant phenotype:GO:0016236 macroautophagy [PMID:27462928]
experiment: EXISTENCE:mutant phenotype:GO:0031503 protein-containing complex localization [PMID:27462928]
experiment: EXISTENCE:mutant phenotype:GO:0032258 cytoplasm to vacuole transport by the Cvt pathway [PMID:27462928]
experiment: EXISTENCE:mutant phenotype:GO:0034067 protein localization to Golgi apparatus [PMID:26966233]
experiment: EXISTENCE:mutant phenotype:GO:0034497 protein localization to phagophore assembly site [PMID:27462928]
experiment: EXISTENCE:mutant phenotype:GO:0034976 response to endoplasmic reticulum stress [PMID:26966233]
experiment: EXISTENCE:mutant phenotype:GO:0043001 Golgi to plasma membrane protein transport [PMID:16926193]
note: Soluble GTPase with a role in regulation of membrane traffic; regulates potassium influx; role in membrane organization at trans-Golgi network; required for delivery of Atg9p to the phagophore assembly site during autophagy under high temperature stress; required with Ypt6p for starvation-induced autophagy; required for the CVT pathway under non-starvation conditions; G protein of the Ras superfamily, similar to ADP-ribosylation factor
codon start: 1
product: Arf family GTPase ARL1
translation: MGNIFSSMFDKLWGSNKELRILILGLDGAGKTTILYRLQIGEVVTTKPTIGFNVETLSYKNLKLNVWDLGGQTSIRPYWRCYYADTAAVIFVVDSTDKDRMSTASKELHLMLQEEELQDAALLVFANKQDQPGALSASEVSKELNLVELKDRSWSIVASSAIKGEGITEGLDWLIDVIKEEQL
SIO_010081: YBR164C
subclass of: SO_0000673
so part of: YBR164C
location: complement(567875..568426)
location: region:567875-568426:-1
so has part: feature:567875-568426:-1:exon

NP_009723.3
type: Protein
SIO_000068: ncbiprotein

S000000368
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:567875-568426:-1:exon

YBR165W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: UBS1
locus tag: YBR165W
so part of: sequence
location: <568852..>569685
location: region:568852-569685:1
so has part: feature:568852-569685:1:exon
subclass of: SO_0000010

852463
type: Gene
SIO_000068: ncbigene

position:568852:1
position: 568852
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:569685:1
position: 569685
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:568852-569685:1:exon

YBR165W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: UBS1
locus tag: YBR165W
product: Ubs1p
transcript id: NM_001178513.1
SIO_010081: YBR165W
subclass of: SO_0000673
so part of: YBR165W
location: <568852..>569685
location: region:568852-569685:1
so has part: feature:568852-569685:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:568852-569685:1:exon

YBR165W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: UBS1
locus tag: YBR165W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:10991951]
experiment: EXISTENCE:mutant phenotype:GO:0006611 protein export from nucleus [PMID:10991951]
experiment: EXISTENCE:mutant phenotype:GO:0016567 protein ubiquitination [PMID:10991951]
note: Ubiquitin-conjugating enzyme suppressor that regulates Cdc34p; functions as a general positive regulator of Cdc34p activity; nuclear protein that may represent a link between nucleocytoplasmic transport and ubiquitin ligase activity
codon start: 1
product: Ubs1p
translation: MAYSLTRKLLKDWKYFMRHPEKTQGLFHVRPHDSDLHLWHVVMYEPRTSLEVYLLLYIGGNDQDPYIIMKCLSPNCCFPINRTVSMTHLNYLLLKDLGLQDLLFHIWQPLFHIQATEDLQYSPSTVKFNRAWNRIIYKDFKSYFPELIGTLQPGDYSIVKSYSKNHNISNSNGGSVNEFMSSYNAQSHTFHAQDNSKNPYTNSSIGKSSMLSTLNNNNVNKRTHDYNAIDFMTKNLLACDDDSIHPVVSSKRSRTLACPDETNDNRGSEHYTKRKKI
SIO_010081: YBR165W
subclass of: SO_0000673
so part of: YBR165W
location: 568852..569685
location: region:568852-569685:1
so has part: feature:568852-569685:1:exon

NP_009724.1
type: Protein
SIO_000068: ncbiprotein

S000000369
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:568852-569685:1:exon

YBR166C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TYR1
locus tag: YBR166C
so part of: sequence
location: complement(<569842..>571200)
location: region:569842-571200:-1
so has part: feature:569842-571200:-1:exon
subclass of: SO_0000010

852464
type: Gene
SIO_000068: ncbigene

position:569842:-1
position: 569842
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:571200:-1
position: 571200
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:569842-571200:-1:exon

YBR166C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: TYR1
locus tag: YBR166C
product: prephenate dehydrogenase (NADP(+))
transcript id: NM_001178514.1
SIO_010081: YBR166C
subclass of: SO_0000673
so part of: YBR166C
location: complement(<569842..>571200)
location: region:569842-571200:-1
so has part: feature:569842-571200:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:569842-571200:-1:exon

YBR166C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: TYR1
locus tag: YBR166C
EC number: 1.3.1.13
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0006571 tyrosine biosynthetic process [PMID:30771296]
experiment: EXISTENCE:direct assay:GO:0008977 prephenate dehydrogenase (NAD+) activity [PMID:30771296]
experiment: EXISTENCE:mutant phenotype:GO:0006570 tyrosine metabolic process [PMID:2697638]
experiment: EXISTENCE:mutant phenotype:GO:0008977 prephenate dehydrogenase (NAD+) activity [PMID:2697638]
note: Prephenate dehydrogenase involved in tyrosine biosynthesis; expression is dependent on phenylalanine levels
codon start: 1
product: prephenate dehydrogenase (NADP(+))
translation: MVSEDKIEQWKATKVIGIIGLGDMGLLYANKFTDAGWGVICCDREEYYDELKEKYASAKFELVKNGHLVSRQSDYIIYSVEASNISKIVATYGPSSKVGTIVGGQTSCKLPEIEAFEKYLPKDCDIITVHSLHGPKVNTEGQPLVIINHRSQYPESFEFVNSVMACLKSKQVYLTYEEHDKITADTQAVTHAAFLSMGSAWAKIKIYPWTLGVNKWYGGLENVKVNISLRIYSNKWHVYAGLAITNPSAHQQILQYATSATELFSLMIDNKEQELTDRLLKAKQFVFGKHTGLLLLDDTILEKYSLSKSSIGNSNNCKPVPNSHLSLLAIVDSWFQLGIDPYDHMICSTPLFRIFLGVSEYLFLKPGLLEQTIDAAIHDKSFIKDDLEFVISAREWSSVVSFANFDIYKKQFQSVQKFFEPMLPEANLIGNEMIKTILSHSSDRSAAEKRNT
SIO_010081: YBR166C
subclass of: SO_0000673
so part of: YBR166C
location: complement(569842..571200)
location: region:569842-571200:-1
so has part: feature:569842-571200:-1:exon

NP_009725.1
type: Protein
SIO_000068: ncbiprotein

S000000370
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:569842-571200:-1:exon

YBR167C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RPP2
gene: POP7
locus tag: YBR167C
gene synonym: RPP2
so part of: sequence
location: complement(<571468..>571890)
location: region:571468-571890:-1
so has part: feature:571468-571890:-1:exon
subclass of: SO_0000010

852465
type: Gene
SIO_000068: ncbigene

position:571468:-1
position: 571468
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:571890:-1
position: 571890
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:571468-571890:-1:exon

YBR167C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RPP2
gene: POP7
locus tag: YBR167C
gene synonym: RPP2
product: ribonuclease P/MRP protein subunit POP7
transcript id: NM_001178515.3
SIO_010081: YBR167C
subclass of: SO_0000673
so part of: YBR167C
location: complement(<571468..>571890)
location: region:571468-571890:-1
so has part: feature:571468-571890:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:571468-571890:-1:exon

YBR167C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RPP2
gene: POP7
locus tag: YBR167C
gene synonym: RPP2
EC number: 3.1.26.5
experiment: EXISTENCE:direct assay:GO:0000171 ribonuclease MRP activity [PMID:9620854]
experiment: EXISTENCE:direct assay:GO:0000172 ribonuclease MRP complex [PMID:9620854]
experiment: EXISTENCE:direct assay:GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay [PMID:14729943]
experiment: EXISTENCE:direct assay:GO:0003723 RNA binding [PMID:26135751]
experiment: EXISTENCE:direct assay:GO:0004526 ribonuclease P activity [PMID:9620854]
experiment: EXISTENCE:direct assay:GO:0005655 nucleolar ribonuclease P complex [PMID:9618478|PMID:9620854]
experiment: EXISTENCE:direct assay:GO:0005697 telomerase holoenzyme complex [PMID:27156450]
experiment: EXISTENCE:direct assay:GO:0034965 intronic box C/D RNA processing [PMID:18713869]
experiment: EXISTENCE:mutant phenotype:GO:0000171 ribonuclease MRP activity [PMID:9620854]
experiment: EXISTENCE:mutant phenotype:GO:0000172 ribonuclease MRP complex [PMID:9618478]
experiment: EXISTENCE:mutant phenotype:GO:0004526 ribonuclease P activity [PMID:9620854]
experiment: EXISTENCE:mutant phenotype:GO:0006364 rRNA processing [PMID:9618478|PMID:9620854]
experiment: EXISTENCE:mutant phenotype:GO:0008033 tRNA processing [PMID:9618478|PMID:9620854]
experiment: EXISTENCE:physical interaction:GO:0000172 ribonuclease MRP complex [PMID:17881380]
note: Subunit of RNase MRP, nuclear RNase P and telomerase; forms a soluble heterodimer with Pop6p that binds P3 domain of RNase MRP and RNase P RNAs; RNase MRP cleaves pre-rRNA, nuclear RNase P cleaves tRNA precursors to generate mature 5' ends and facilitates turnover of nuclear RNAs, while telomerase replenishes telomeric DNA
codon start: 1
product: ribonuclease P/MRP protein subunit POP7
translation: MALKKNTHNKSTKRVTKHPSLKTLTHKQIHTTIFVKSTTPYVSALKRINKFLDSVHKQGSSYVAVLGMGKAVEKTLALGCHFQDQKNKKIEVYTKTIEVLDEVITEGQADIDMESDVEDDDKETQLKKRAVSGVELRIYV
SIO_010081: YBR167C
subclass of: SO_0000673
so part of: YBR167C
location: complement(571468..571890)
location: region:571468-571890:-1
so has part: feature:571468-571890:-1:exon

NP_009726.3
type: Protein
SIO_000068: ncbiprotein

S000000371
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:571468-571890:-1:exon

YBR168W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PEX32
locus tag: YBR168W
so part of: sequence
location: <572371..>573612
location: region:572371-573612:1
so has part: feature:572371-573612:1:exon
subclass of: SO_0000010

852466
type: Gene
SIO_000068: ncbigene

position:572371:1
position: 572371
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:573612:1
position: 573612
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:572371-573612:1:exon

YBR168W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PEX32
locus tag: YBR168W
product: Pex32p
transcript id: NM_001178516.3
SIO_010081: YBR168W
subclass of: SO_0000673
so part of: YBR168W
location: <572371..>573612
location: region:572371-573612:1
so has part: feature:572371-573612:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:572371-573612:1:exon

YBR168W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PEX32
locus tag: YBR168W
experiment: EXISTENCE:direct assay:GO:0005778 peroxisomal membrane [PMID:14617799]
experiment: EXISTENCE:mutant phenotype:GO:0007031 peroxisome organization [PMID:14617799]
note: Peroxisomal integral membrane protein; involved in negative regulation of peroxisome size; partially functionally redundant with Pex31p; genetic interactions suggest action at a step downstream of steps mediated by Pex28p and Pex29p
codon start: 1
product: Pex32p
translation: MDTNSKTKVQTENKKIKAKFIHNHGQKPSLIQITPPMISSTLFHAYPLLLIFDNALANIMWLSDDKCLTFIYLTSIWLTISFFIPVETEASHFLPFTKILRLWLGIISGAFLFLSFMYYIVSLIASLRDTEPPTLDEIVVLLESVLDKLEVLRNELNVWKKLKLSFDGVNKECSGKRLFCRLFLFGTIFQIIIMRYISPGTYTRFFIITGLIYNTSSFQATLRLLWRFTAVRNFYYLGIESFKISSFLPKHLKMEQIIPLSQGRAITVPLVEVLPKLLRDKKGDDHIHILQLLLNEQKDNFGNEDLKILEIEVYENQRRWYQNKNWSTKLLPYERQNYCIEIKNTDGTLTMRSCLPPDGLGEEELPNNWHWINDNWDGTDWIYSDSAWKEIGQYSSLESFTRSRKWKRRLFHL
SIO_010081: YBR168W
subclass of: SO_0000673
so part of: YBR168W
location: 572371..573612
location: region:572371-573612:1
so has part: feature:572371-573612:1:exon

NP_009727.3
type: Protein
SIO_000068: ncbiprotein

S000000372
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:572371-573612:1:exon

YBR169C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SSE2
locus tag: YBR169C
so part of: sequence
location: complement(<573915..>575996)
location: region:573915-575996:-1
so has part: feature:573915-575996:-1:exon
subclass of: SO_0000010

852467
type: Gene
SIO_000068: ncbigene

position:573915:-1
position: 573915
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:575996:-1
position: 575996
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:573915-575996:-1:exon

YBR169C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SSE2
locus tag: YBR169C
product: adenyl-nucleotide exchange factor SSE2
transcript id: NM_001178517.1
SIO_010081: YBR169C
subclass of: SO_0000673
so part of: YBR169C
location: complement(<573915..>575996)
location: region:573915-575996:-1
so has part: feature:573915-575996:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:573915-575996:-1:exon

YBR169C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SSE2
locus tag: YBR169C
experiment: EXISTENCE:direct assay:GO:0000774 adenyl-nucleotide exchange factor activity [PMID:16688212]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:genetic interaction:GO:0010499 proteasomal ubiquitin-independent protein catabolic process [PMID:29507114]
experiment: EXISTENCE:genetic interaction:GO:0042026 protein refolding [PMID:16688211]
experiment: EXISTENCE:genetic interaction:GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process [PMID:29507114]
note: Member of Hsp110 subclass of the heat shock protein 70 (HSP70) family; serves as nucleotide exchange factor to load ATP onto the SSA class of cytosolic Hsp70s; may be involved in protein folding; localized to the cytoplasm; SSE2 has a paralog, SSE1, that arose from the whole genome duplication
codon start: 1
product: adenyl-nucleotide exchange factor SSE2
translation: MSTPFGLDLGNNNSVLAVARNRGIDVVVNEVSNRSTPSLVGFGPRNRYLGESGKTKQTSNVKNTVENLKRIIGLKFKDPEFDIENKFFTSKLVQLKNGKVGVEVEFGGKTHVFSATQLTAMFIDKVKHTVQEETKSSITDVCLAVPVWYSEEQRYNIADAARIAGLNPVRIVNDVTAAAVSYGVFKNDLPGPEEKPRIIGLVDIGHSTYTCSIMAFRKGEMKVLGTAYDKHFGGRDFDRAITEHFADQFKDKYKIDIRKNPKAYNRILIAAEKLKKVLSANTTAPFSVESVMDDIDVSSQLSREELEELVEPLLKRVTYPITNALAQAKLTVNDIDFVEIIGGTTRIPVLKKSISDVFGKPLSSTLNQDEAVAKGAAFICAIHSPTLRVRPFKFEDIDPYSVSYTWDKQVDDEDRLEVFPANSSYPSTKLITLHRTGDFSMKAVYTHPSKLPKGTSTTIAKWSFTGVKVPKDQDFIPVKVKLRCDPSGLHIIENAYTTEDITVQEPVPLPEDAPEDAEPQFKEVTKTIKKDVLGMTAKTFALNPVELNDLIEKENELRNQDKLVAETEDRKNALEEYIYTLRAKLDDEYSDFASDAEKEKLKNMLATTENWLYGDGDDSTKAKYIAKYEELASLGNIIRGRYLAKEEEKRQALRANQETSKMNDIAEKLAEQRRARAASDDSDDNNDENMDLD
SIO_010081: YBR169C
subclass of: SO_0000673
so part of: YBR169C
location: complement(573915..575996)
location: region:573915-575996:-1
so has part: feature:573915-575996:-1:exon

NP_009728.1
type: Protein
SIO_000068: ncbiprotein

S000000373
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:573915-575996:-1:exon

YBR170C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: HRD4
gene: NPL4
locus tag: YBR170C
gene synonym: HRD4
so part of: sequence
location: complement(<576344..>578086)
location: region:576344-578086:-1
so has part: feature:576344-578086:-1:exon
subclass of: SO_0000010

852468
type: Gene
SIO_000068: ncbigene

position:576344:-1
position: 576344
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:578086:-1
position: 578086
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:576344-578086:-1:exon

YBR170C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: HRD4
gene: NPL4
locus tag: YBR170C
gene synonym: HRD4
product: nuclear protein localization protein 4
transcript id: NM_001178518.1
SIO_010081: YBR170C
subclass of: SO_0000673
so part of: YBR170C
location: complement(<576344..>578086)
location: region:576344-578086:-1
so has part: feature:576344-578086:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:576344-578086:-1:exon

YBR170C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: HRD4
gene: NPL4
locus tag: YBR170C
gene synonym: HRD4
experiment: EXISTENCE:direct assay:GO:0000837 Doa10p ubiquitin ligase complex [PMID:16873066]
experiment: EXISTENCE:direct assay:GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex [PMID:16873065|PMID:16873066]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22842922|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0006274 DNA replication termination [PMID:31509741]
experiment: EXISTENCE:direct assay:GO:0030894 replisome [PMID:31509741]
experiment: EXISTENCE:direct assay:GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex [PMID:11598205|PMID:11733065]
experiment: EXISTENCE:direct assay:GO:0036266 Cdc48p-Npl4p-Vms1p AAA ATPase complex [PMID:21070972]
experiment: EXISTENCE:direct assay:GO:0036435 K48-linked polyubiquitin modification-dependent protein binding [PMID:28525741]
experiment: EXISTENCE:direct assay:GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network [PMID:11598205]
experiment: EXISTENCE:direct assay:GO:1990112 RQC complex [PMID:23178123]
experiment: EXISTENCE:mutant phenotype:GO:0030433 ubiquitin-dependent ERAD pathway [PMID:11739805]
experiment: EXISTENCE:mutant phenotype:GO:0030970 retrograde protein transport, ER to cytosol [PMID:11740563]
experiment: EXISTENCE:mutant phenotype:GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process [PMID:20206597]
experiment: EXISTENCE:mutant phenotype:GO:0051228 mitotic spindle disassembly [PMID:14636562]
experiment: EXISTENCE:mutant phenotype:GO:0051974 negative regulation of telomerase activity [PMID:26365526]
experiment: EXISTENCE:mutant phenotype:GO:0070651 nonfunctional rRNA decay [PMID:22505030]
experiment: EXISTENCE:mutant phenotype:GO:0071629 cytoplasm protein quality control by the ubiquitin-proteasome system [PMID:18812321]
experiment: EXISTENCE:mutant phenotype:GO:0071712 ER-associated misfolded protein catabolic process [PMID:11740563|PMID:11813000]
experiment: EXISTENCE:mutant phenotype:GO:0072665 protein localization to vacuole [PMID:29444958]
experiment: EXISTENCE:mutant phenotype:GO:0072671 mitochondria-associated ubiquitin-dependent protein catabolic process [PMID:32118579|PMID:21070972]
experiment: EXISTENCE:mutant phenotype:GO:0099638 endosome to plasma membrane protein transport [PMID:36125415]
experiment: EXISTENCE:mutant phenotype:GO:1900182 positive regulation of protein localization to nucleus [PMID:11598205|PMID:11733065]
experiment: EXISTENCE:mutant phenotype:GO:1990116 ribosome-associated ubiquitin-dependent protein catabolic process [PMID:23358411]
note: Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase; K48-specific Ub chain binding receptor that assists Cdc48p in the dislocation of misfolded, polyubiquitinated ERAD substrates destined for proteasomal degradation; role in regulated destruction of ER membrane proteins, like HMG-CoA reductase (Hmg1/2p), cytosolic proteins (Fbp1p) and mislocalized proteins (Cse4p); mobilizes membrane-bound transcription factors by regulated Ub/proteasome-dependent processing; contains a UBX domain
codon start: 1
product: nuclear protein localization protein 4
translation: MLIRFRSKNGTHRVSCQENDLFGTVIEKLVGNLDPNADVDTFTVCEKPGQGIHAVSELADRTVMDLGLKHGDMLILNYSDKPANEKDGVNVEIGSVGIDSKGIRQHRYGPLRIKELAVDEELEKEDGLIPRQKSKLCKHGDRGMCEYCSPLPPWDKEYHEKNKIKHISFHSYLKKLNENANKKENGSSYISPLSEPDFRINKRCHNGHEPWPRGICSKCQPSAITLQQQEFRMVDHVEFQKSEIINEFIQAWRYTGMQRFGYMYGSYSKYDNTPLGIKAVVEAIYEPPQHDEQDGLTMDVEQVKNEMLQIDRQAQEMGLSRIGLIFTDLSDAGAGDGSVFCKRHKDSFFLSSLEVIMAARHQTRHPNVSKYSEQGFFSSKFVTCVISGNLEGEIDISSYQVSTEAEALVTADMISGSTFPSMAYINDTTDERYVPEIFYMKSNEYGITVKENAKPAFPVDYLLVTLTHGFPNTDTETNSKFVSSTGFPWSNRQAMGQSQDYQELKKYLFNVASSGDFNLLHEKISNFHLLLYINSLQILSPDEWKLLIESAVKNEWEESLLKLVSSAGWQTLVMILQESG
SIO_010081: YBR170C
subclass of: SO_0000673
so part of: YBR170C
location: complement(576344..578086)
location: region:576344-578086:-1
so has part: feature:576344-578086:-1:exon

NP_009729.1
type: Protein
SIO_000068: ncbiprotein

S000000374
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:576344-578086:-1:exon

YBR171W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: HSS1
alternative label: KAR7
alternative label: SEC71
gene: SEC66
locus tag: YBR171W
gene synonym: HSS1; KAR7; SEC71
so part of: sequence
location: <578364..>578984
location: region:578364-578984:1
so has part: feature:578364-578984:1:exon
subclass of: SO_0000010

852469
type: Gene
SIO_000068: ncbigene

position:578364:1
position: 578364
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:578984:1
position: 578984
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:578364-578984:1:exon

YBR171W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: HSS1
alternative label: KAR7
alternative label: SEC71
gene: SEC66
locus tag: YBR171W
gene synonym: HSS1; KAR7; SEC71
product: Sec63 complex subunit SEC66
transcript id: NM_001178519.3
SIO_010081: YBR171W
subclass of: SO_0000673
so part of: YBR171W
location: <578364..>578984
location: region:578364-578984:1
so has part: feature:578364-578984:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:578364-578984:1:exon

YBR171W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: HSS1
alternative label: KAR7
alternative label: SEC71
gene: SEC66
locus tag: YBR171W
gene synonym: HSS1; KAR7; SEC71
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:14562095|PMID:26928762|PMID:27831485]
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:9275186]
experiment: EXISTENCE:direct assay:GO:0008320 protein transmembrane transporter activity [PMID:9252322]
experiment: EXISTENCE:direct assay:GO:0031204 post-translational protein targeting to membrane, translocation [PMID:7758110]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0031204 post-translational protein targeting to membrane, translocation [PMID:32513868]
experiment: EXISTENCE:mutant phenotype:GO:0030447 filamentous growth [PMID:15645503]
experiment: EXISTENCE:mutant phenotype:GO:0031204 post-translational protein targeting to membrane, translocation [PMID:8257795|PMID:32513868]
experiment: EXISTENCE:physical interaction:GO:0031207 Sec62/Sec63 complex [PMID:8257795]
note: Non-essential subunit of Sec63 complex; with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and translocation into the ER; other members are Sec63p, Sec62p, and Sec72p
codon start: 1
product: Sec63 complex subunit SEC66
translation: MSEFNETKFSNNGTFFETEEPIVETKSISVYTPLIYVFILVVSLVMFASSYRKKQAKKISEQPSIFDENDAHDLYFQIKEMSENEKIHEKVLKAALLNRGAESVRRSLKLKELAPQINLLYKNGSIGEDYWKRFETEVKLIELEFKDTLQEAERLQPGWVQLFVMVCKEICFNQALSRRYQSILKRKEVCIKEWELKINNDGRLVN
SIO_010081: YBR171W
subclass of: SO_0000673
so part of: YBR171W
location: 578364..578984
location: region:578364-578984:1
so has part: feature:578364-578984:1:exon

NP_009730.3
type: Protein
SIO_000068: ncbiprotein

S000000375
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:578364-578984:1:exon

YBR172C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SMY2
locus tag: YBR172C
so part of: sequence
location: complement(<579150..>581372)
location: region:579150-581372:-1
so has part: feature:579150-581372:-1:exon
subclass of: SO_0000010

852470
type: Gene
SIO_000068: ncbigene

position:579150:-1
position: 579150
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:581372:-1
position: 581372
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:579150-581372:-1:exon

YBR172C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SMY2
locus tag: YBR172C
product: Smy2p
transcript id: NM_001178520.3
SIO_010081: YBR172C
subclass of: SO_0000673
so part of: YBR172C
location: complement(<579150..>581372)
location: region:579150-581372:-1
so has part: feature:579150-581372:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:579150-581372:-1:exon

YBR172C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SMY2
locus tag: YBR172C
experiment: EXISTENCE:direct assay:GO:0005515 protein binding [PMID:36288698]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:36288698]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:17973654]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport [PMID:17973654]
experiment: EXISTENCE:mutant phenotype:GO:0006357 regulation of transcription by RNA polymerase II [PMID:36288698]
experiment: EXISTENCE:mutant phenotype:GO:0032984 protein-containing complex disassembly [PMID:36288698]
experiment: EXISTENCE:mutant phenotype:GO:0071630 nuclear protein quality control by the ubiquitin-proteasome system [PMID:36288698]
experiment: EXISTENCE:physical interaction:GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport [PMID:17973654]
note: GYF domain protein; involved in COPII vesicle formation; regulates Cdc48p function in transcription stress response; interacts with the Sec23p/Sec24p subcomplex; overexpression suppresses the temperature sensitivity of a myo2 mutant; homologous to human GIGYF1 and GIGYF2; similar to S. pombe Mpd2; SMY2 has a paralog, SYH1, that arose from the whole genome duplication
codon start: 1
product: Smy2p
translation: MIAPDSQRLFGSFDEQFKDLKLDSVDTENNNTHGVSTILDSSPASVNNNTNGAVAASVNTVPGSTFRSNTPLLGGRHPLSRTSSLIDSIGIQRAASPFSSMKEPFIPQSSGVMSSSFWHGDHPESRVSTPVQQHPLLQRNESSSSFSYAANLGVNLSTHSLAVDITPLSTPTAAQSHVNLFPSSDIPPNMSMNGMSQLPAPVSVESSWRYIDTQGQIHGPFTTQMMSQWYIGGYFASTLQISRLGSTPETLGINDIFITLGELMTKLEKYDTDPFTTFDKLHVQTTSSDSINLNLAPYASGVAATGTIKATENDIFKPLTHDNIWDMDGGTTSKGVDIKLASATTISQTDESHKQEYKSTTMLEKGKKEKSESVAKALLDEQEKRNRELKRKEEARLSKKQKQKEDDLLKKQKEQKEQKEKEALEAEKQKKSEKTKKDTQTQTEGFKTSKDLPSLNSSSANPAPWASKVKVNNAIETSIKNGVSSTGKKKGEPLGLQQRNSKEEKQKEELKSVLNWANKSSLPSNQTIDIKSQFQKSPKGMKESSPLKELEDPNFIEEQKKLWEKVQSSSKQVKSTSSASTTTSSWTTVTSKGKAPIGTVVSPYSKTNTSLNSSLTAKTSTTSTTTTFASMNNVSPRQEFIKWCKSQMKLNSGITNNNVLELLLSLPTGPESKELIQETIYANSDVMDGRRFATEFIKRRVACEKQGDDPLSWNEALALSGNDDDGWEFQVVSKKKGRKH
SIO_010081: YBR172C
subclass of: SO_0000673
so part of: YBR172C
location: complement(579150..581372)
location: region:579150-581372:-1
so has part: feature:579150-581372:-1:exon

NP_009731.4
type: Protein
SIO_000068: ncbiprotein

S000000376
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:579150-581372:-1:exon

YBR173C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RNS2
gene: UMP1
locus tag: YBR173C
gene synonym: RNS2
so part of: sequence
location: complement(<581726..>582172)
location: region:581726-582172:-1
so has part: feature:581726-582172:-1:exon
subclass of: SO_0000010

852471
type: Gene
SIO_000068: ncbigene

position:581726:-1
position: 581726
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:582172:-1
position: 582172
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:581726-582172:-1:exon

YBR173C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RNS2
gene: UMP1
locus tag: YBR173C
gene synonym: RNS2
product: Ump1p
transcript id: NM_001178521.1
SIO_010081: YBR173C
subclass of: SO_0000673
so part of: YBR173C
location: complement(<581726..>582172)
location: region:581726-582172:-1
so has part: feature:581726-582172:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:581726-582172:-1:exon

YBR173C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RNS2
gene: UMP1
locus tag: YBR173C
gene synonym: RNS2
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:11922673]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11922673]
experiment: EXISTENCE:direct assay:GO:0006974 cellular response to DNA damage stimulus [PMID:10975253]
experiment: EXISTENCE:genetic interaction:GO:0043248 proteasome assembly [PMID:17431397]
experiment: EXISTENCE:mutant phenotype:GO:0006511 ubiquitin-dependent protein catabolic process [PMID:9491890]
experiment: EXISTENCE:mutant phenotype:GO:0043248 proteasome assembly [PMID:9491890]
note: Chaperone required for correct maturation of the 20S proteasome; short-lived chaperone; may inhibit premature dimerization of proteasome half-mers; degraded by proteasome upon completion of its assembly
codon start: 1
product: Ump1p
translation: MNIVPQDTFKSQVSTDQDKSVLSSAVPSLPDTLRQQEGGAVPLSTQLNDRHPLESTLKNWETTQRQRQMEQYRQIFGIAEPMKRTMEMEIVNRTDFNPLSTNGSIHRDILLNKECSIDWEDVYPGTGLQASTMVGDDVHSKIEKQLGI
SIO_010081: YBR173C
subclass of: SO_0000673
so part of: YBR173C
location: complement(581726..582172)
location: region:581726-582172:-1
so has part: feature:581726-582172:-1:exon

NP_009732.1
type: Protein
SIO_000068: ncbiprotein

S000000377
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:581726-582172:-1:exon

YBR175W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CPS30
alternative label: SAF35
gene: SWD3
locus tag: YBR175W
gene synonym: CPS30; SAF35
so part of: sequence
location: <582408..>583355
location: region:582408-583355:1
so has part: feature:582408-583355:1:exon
subclass of: SO_0000010

852472
type: Gene
SIO_000068: ncbigene

position:582408:1
position: 582408
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:583355:1
position: 583355
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:582408-583355:1:exon

YBR175W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CPS30
alternative label: SAF35
gene: SWD3
locus tag: YBR175W
gene synonym: CPS30; SAF35
product: Swd3p
transcript id: NM_001178523.1
SIO_010081: YBR175W
subclass of: SO_0000673
so part of: YBR175W
location: <582408..>583355
location: region:582408-583355:1
so has part: feature:582408-583355:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:582408-583355:1:exon

YBR175W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CPS30
alternative label: SAF35
gene: SWD3
locus tag: YBR175W
gene synonym: CPS30; SAF35
experiment: EXISTENCE:direct assay:GO:0042800 histone H3K4 methyltransferase activity [PMID:11742990|PMID:11805083]
experiment: EXISTENCE:mutant phenotype:GO:0000723 telomere maintenance [PMID:11742990]
experiment: EXISTENCE:mutant phenotype:GO:0031509 subtelomeric heterochromatin formation [PMID:11687631|PMID:11752412|PMID:11805083]
experiment: EXISTENCE:mutant phenotype:GO:0042800 histone H3K4 methyltransferase activity [PMID:11752412|PMID:11805083]
experiment: EXISTENCE:mutant phenotype:GO:1903341 regulation of meiotic DNA double-strand break formation [PMID:23246437]
experiment: EXISTENCE:physical interaction:GO:0048188 Set1C/COMPASS complex [PMID:11687631|PMID:11752412|PMID:11742990]
note: Essential subunit of the COMPASS (Set1C) complex; COMPASS methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member and ortholog of mammalian WDR5
codon start: 1
product: Swd3p
translation: MFQFVTPVGTQNGLKATCAKISPDGQFLAITQGLNILIYDINRRTVSQTLVTSHARPFSELCWSPDGQCIATASDDFSVEIIHLSYGLLHTFIGHTAPVISLTFNRKGNLLFTSSMDESIKIWDTLNGSLMKTISAHSEAVVSVDVPMNDSSILSSGSYDGLIRIFDAETGHCLKTLTYDKDWKRENGVVPISQVKFSENARYLLVKSLDGVVKIWDCIGGCVVRTFQVQPLEKGVLHHSCGMDFLNPEDGSTPLVISGYENGDIYCWNSDTKSLLQLLDGSLYHHSSPVMSIHCFGNIMCSLALNGDCCLWRWV
SIO_010081: YBR175W
subclass of: SO_0000673
so part of: YBR175W
location: 582408..583355
location: region:582408-583355:1
so has part: feature:582408-583355:1:exon

NP_009734.1
type: Protein
SIO_000068: ncbiprotein

S000000379
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:582408-583355:1:exon

YBR176W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ECM31
locus tag: YBR176W
so part of: sequence
location: <583720..>584658
location: region:583720-584658:1
so has part: feature:583720-584658:1:exon
subclass of: SO_0000010

852474
type: Gene
SIO_000068: ncbigene

position:583720:1
position: 583720
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:584658:1
position: 584658
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:583720-584658:1:exon

YBR176W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ECM31
locus tag: YBR176W
product: 3-methyl-2-oxobutanoate hydroxymethyltransferase
transcript id: NM_001178524.3
SIO_010081: YBR176W
subclass of: SO_0000673
so part of: YBR176W
location: <583720..>584658
location: region:583720-584658:1
so has part: feature:583720-584658:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:583720-584658:1:exon

YBR176W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ECM31
locus tag: YBR176W
EC number: 2.1.2.11
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:17054397|PMID:14562095|PMID:14576278|PMID:16823961|P MID:24769239]
experiment: EXISTENCE:mutant phenotype:GO:0003864 3-methyl-2-oxobutanoate hydroxymethyltransferase activity [PMID:11154694]
experiment: EXISTENCE:mutant phenotype:GO:0015940 pantothenate biosynthetic process [PMID:11154694]
note: Ketopantoate hydroxymethyltransferase; required for pantothenic acid biosynthesis, converts 2-oxoisovalerate into 2-dehydropantoate
codon start: 1
product: 3-methyl-2-oxobutanoate hydroxymethyltransferase
translation: MNIMKRQLCTSSKRFFSTAKNVVKYNTIQDIRNKYFTGTPLSMCTAYDFITATWVNKANCDLLLVGDSLAMTSLGYDSTITLSLNEFKYHVASVCRAEGSSMVVVDMPFGTFESGISDGLKNAIDIMKLDSKVTSVKVEVGSYTKDKYAMKFIEELCSRGIPVMAHIGLTPQKVHSLGGYKVQGSKSLLQMQELYETAMQLQKIGCWSILIECVPHKMAQFITSKLSVPTIGIGAGNGTSGQVLVISDLLGMQGDSVPKFVKQAVNMTDIATQGLKEYIASVEDRTFPERGTHTFKVKEDLWNEFLSSINEK
SIO_010081: YBR176W
subclass of: SO_0000673
so part of: YBR176W
location: 583720..584658
location: region:583720-584658:1
so has part: feature:583720-584658:1:exon

NP_009735.3
type: Protein
SIO_000068: ncbiprotein

S000000380
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:583720-584658:1:exon

YBR177C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: EHT1
locus tag: YBR177C
so part of: sequence
location: complement(<584807..>586162)
location: region:584807-586162:-1
so has part: feature:584807-586162:-1:exon
subclass of: SO_0000010

852476
type: Gene
SIO_000068: ncbigene

position:584807:-1
position: 584807
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:586162:-1
position: 586162
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:584807-586162:-1:exon

YBR177C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: EHT1
locus tag: YBR177C
product: medium-chain fatty acid ethyl ester synthase/esterase
transcript id: NM_001178525.3
SIO_010081: YBR177C
subclass of: SO_0000673
so part of: YBR177C
location: complement(<584807..>586162)
location: region:584807-586162:-1
so has part: feature:584807-586162:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:584807-586162:-1:exon

YBR177C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: EHT1
locus tag: YBR177C
EC number: 2.3.1.84
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005741 mitochondrial outer membrane [PMID:16407407]
experiment: EXISTENCE:direct assay:GO:0005811 lipid droplet [PMID:10515935|PMID:24868093]
experiment: EXISTENCE:direct assay:GO:0017171 serine hydrolase activity [PMID:14645503]
experiment: EXISTENCE:direct assay:GO:0034319 alcohol O-butanoyltransferase activity [PMID:16361250]
experiment: EXISTENCE:direct assay:GO:0034338 short-chain carboxylesterase activity [PMID:16361250]
experiment: EXISTENCE:direct assay:GO:0051792 medium-chain fatty acid biosynthetic process [PMID:16361250]
experiment: EXISTENCE:mutant phenotype:GO:0044255 cellular lipid metabolic process [PMID:10515935]
experiment: EXISTENCE:mutant phenotype:GO:0051792 medium-chain fatty acid biosynthetic process [PMID:16361250]
experiment: EXISTENCE:mutant phenotype:GO:0051793 medium-chain fatty acid catabolic process [PMID:16361250]
note: Octanoyl-CoA:ethanol acyltransferase; also functions as thioesterase; plays a minor role in medium-chain fatty acid ethyl ester biosynthesis; localizes to lipid particles and the mitochondrial outer membrane; EHT1 has a paralog, EEB1, that arose from the whole genome duplication
codon start: 1
product: medium-chain fatty acid ethyl ester synthase/esterase
translation: MSEVSKWPAINPFHWGYNGTVSHIVGENGSIKLHLKDNKEQVDFDEFANKYVPTLKNGAQFKLSPYLFTGILQTLYLGAADFSKKFPVFYGREIVKFSDGGVCTADWLIDSWKKDYEFDQSTTSFDKKKFDKDEKATHPEGWPRLQPRTRYLKDNELEELREVDLPLVVILHGLAGGSHEPIIRSLAENLSRSGRFQVVVLNTRGCARSKITTRNLFTAYHTMDIREFLQREKQRHPDRKLYAVGCSFGATMLANYLGEEGDKSPLSAAATLCNPWDLLLSAIRMSQDWWSRTLFSKNIAQFLTRTVQVNMGELGVPNGSLPDHPPTVKNPSFYMFTPENLIKAKSFKSTREFDEVYTAPALGFPNAMEYYKAASSINRVDTIRVPTLVINSRDDPVVGPDQPYSIVEKNPRILYCRTDLGGHLAYLDKDNNSWATKAIAEFFTKFDELVV
SIO_010081: YBR177C
subclass of: SO_0000673
so part of: YBR177C
location: complement(584807..586162)
location: region:584807-586162:-1
so has part: feature:584807-586162:-1:exon

NP_009736.3
type: Protein
SIO_000068: ncbiprotein

S000000381
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:584807-586162:-1:exon

YBR179C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FZO1
locus tag: YBR179C
so part of: sequence
location: complement(<586547..>589114)
location: region:586547-589114:-1
so has part: feature:586547-589114:-1:exon
subclass of: SO_0000010

852477
type: Gene
SIO_000068: ncbigene

position:586547:-1
position: 586547
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:589114:-1
position: 589114
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:586547-589114:-1:exon

YBR179C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FZO1
locus tag: YBR179C
product: mitofusin
transcript id: NM_001178527.1
SIO_010081: YBR179C
subclass of: SO_0000673
so part of: YBR179C
location: complement(<586547..>589114)
location: region:586547-589114:-1
so has part: feature:586547-589114:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:586547-589114:-1:exon

YBR179C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FZO1
locus tag: YBR179C
experiment: EXISTENCE:direct assay:GO:0003924 GTPase activity [PMID:19812251]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005741 mitochondrial outer membrane [PMID:11266460|PMID:9685359|PMID:9786948|PMID:16407407]
experiment: EXISTENCE:direct assay:GO:0005743 mitochondrial inner membrane [PMID:11266460]
experiment: EXISTENCE:genetic interaction:GO:0048312 intracellular distribution of mitochondria [PMID:23341591]
experiment: EXISTENCE:mutant phenotype:GO:0008053 mitochondrial fusion [PMID:9786948|PMID:12808034]
experiment: EXISTENCE:physical interaction:GO:0008053 mitochondrial fusion [PMID:12808034]
note: Mitofusin, protein involved in mitochondrial outer membrane fusion; role in mitochondrial genome maintenance; efficient tethering and degradation of Fzo1p requires an intact N-terminal GTPase domain; targeted for destruction by the ubiquitin ligase SCF-Mdm30p and the cytosolic ubiquitin-proteasome system; activity regulated by ubiquitylation at conserved lysine residues and by deubiquitylases Ubp2p and Ubp12p
codon start: 1
product: mitofusin
translation: MSEGKQQFKDSNKPHKDSTDQDDDAATIVPQTLTYSRNEGHFLGSNFHGVTDDRTTLFDGEEGRREDDLLPSLRSSNSKAHLISSQLSQWNYNNNRVLLKRSILKTQAFMDQLQEENNIRPIFIAANDEREKLHVLQLNIKLDGQYNTKEKNGFNIEKKALSKLFHSQIVSVTNHLNALKKRVDDVSSKVFITGDVNTGKSALCNSLLKQRLLPEDQLPCTNVFSEILEARENDGIEEVHAIPLNIAPTLKEAIDMYSIQNPKTYEIHTLKELPDLVPQNGKYALLKIYIKDDKRPASTSLLRNGTVDISLIDSPGLNMDSLQTAEVMSRQEEIDLVIFVVNAENQLTLSAKEFISLASREKKLMFFVVKKFDKIRDKQRCKELILKQIRDLSPETYKRAADFVHFVSKNGDELPHYHNENDNEDHGDRKPDDDPYSSSDPDPDFDSLEDSLRNFVLKKRSLSKLLPAKTYLSKLLSDIIMISKSNMKMYSEEEIKINEQLETLRPEILSARAKCNDLTTSVDQMAEQTITMTYNNTKEALLNALDVPLHEYPKYQGLGQIYDFIFSTEAFIANQIDESIGSSELFAKQKTDLLVKKIYEIGKNELGDDFMCERVFRSELMFRKRKHLIGKRLKVSLSITDLFAPTWKGFLSYLSWQKPVTAPLPDIEGQTNEGQIGLMKYLGLKNYPLTQYWSRPSLLFTSKIPTLTLYFLGSTKVVGNIILNGIKLSSWSSLKKLSVPVIVVGSLLGLTYLIHDLPRALPMNLSIKYKRKLQELDYIHLNAQRTSNEVRDVLRVPTREILRSCEIIMDKKQITKKELENKKESNLLSIKFFQSLYEGTVAQKLMVEEINLDID
SIO_010081: YBR179C
subclass of: SO_0000673
so part of: YBR179C
location: complement(586547..589114)
location: region:586547-589114:-1
so has part: feature:586547-589114:-1:exon

NP_009738.1
type: Protein
SIO_000068: ncbiprotein

S000000383
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:586547-589114:-1:exon

YBR180W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: DTR1
locus tag: YBR180W
so part of: sequence
location: <589741..>591459
location: region:589741-591459:1
so has part: feature:589741-591459:1:exon
subclass of: SO_0000010

852478
type: Gene
SIO_000068: ncbigene

position:589741:1
position: 589741
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:591459:1
position: 591459
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:589741-591459:1:exon

YBR180W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: DTR1
locus tag: YBR180W
product: Dtr1p
transcript id: NM_001178528.1
SIO_010081: YBR180W
subclass of: SO_0000673
so part of: YBR180W
location: <589741..>591459
location: region:589741-591459:1
so has part: feature:589741-591459:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:589741-591459:1:exon

YBR180W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: DTR1
locus tag: YBR180W
experiment: EXISTENCE:direct assay:GO:0005628 prospore membrane [PMID:12455697|PMID:15755916]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0005275 amine transmembrane transporter activity [PMID:12455697]
experiment: EXISTENCE:mutant phenotype:GO:0015837 amine transport [PMID:12455697]
experiment: EXISTENCE:mutant phenotype:GO:0030476 ascospore wall assembly [PMID:12455697]
experiment: EXISTENCE:mutant phenotype:GO:0055085 transmembrane transport [PMID:12455697]
note: Putative dityrosine transporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; required for spore wall synthesis; sequence similarity to QDR1 and QDR3, and the triple mutant dtr1 qdr1 qdr3 exhibits reduced dityrosine fluorescence relative to the single mutants; expressed during sporulation
codon start: 1
product: Dtr1p
translation: MGSEPFQKKNLGLQINSQESGTTRSTFHSLEDLGDDVINESWDQVNQKRANIDHDVFHEHPDSSPSLSAQKAKTKEEEVAVKSSNSQSRDPSPDTQAHIPYTYFSKDQRLIIFGIIIFIGFLGPMSGNIYIPALPLLQREYDVSATTINATVSVFMAVFSVGPLFWGALADFGGRKFLYMVSLSLMLIVNILLAAVPVNIAALFVLRIFQAFASSSVISLGAGTVTDVVPPKHRGKAIAYFMMGPNMGPIIAPIVAGLILMKGNYWRWLFGFTSIMTGIALILVTALLPETLRCIVGNGDPKWGDKKDERENNESPFFEGNKISHRRLFPDIGIRKPVNNDAFFQENFPKPPKAGLTLYWKMIKCPPIIITSVSTALLFSSYYAFSVTFSYYLEHDYRFTMLEIGAAYVCPGVAMLLGSQSGGHLSDYLRSRWIKSHPKKKFPAEFRLLLNLIGILLTICGTIGYGWAIFFHYHFVVLLVFSALTAFGMTWCSNTSMTYLTELFPKRAAGTVAVSSFFRNVGAAISSAIILQLCNAMGIGWCFTGLGLCSSISLIGILYLLIFQRKYTAKEF
SIO_010081: YBR180W
subclass of: SO_0000673
so part of: YBR180W
location: 589741..591459
location: region:589741-591459:1
so has part: feature:589741-591459:1:exon

NP_009739.1
type: Protein
SIO_000068: ncbiprotein

S000000384
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:589741-591459:1:exon

YBR181C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LPG18
alternative label: RPS101
alternative label: RPS102
gene: RPS6B
locus tag: YBR181C
gene synonym: LPG18; RPS101; RPS102
so part of: sequence
location: complement(<591712..>592774)
location: region:591712-592774:-1
so has part: feature:591712-592774:-1:exon
subclass of: SO_0000010

852479
type: Gene
SIO_000068: ncbigene

position:591712:-1
position: 591712
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:592774:-1
position: 592774
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:591712-592774:-1:exon

YBR181C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LPG18
alternative label: RPS101
alternative label: RPS102
gene: RPS6B
locus tag: YBR181C
gene synonym: LPG18; RPS101; RPS102
product: ribosomal 40S subunit protein S6B
transcript id: NM_001178529.3
SIO_010081: YBR181C
subclass of: SO_0000673
so part of: YBR181C
location: complement(join(<591712..592416,592769..>592774))
location: region:591712-592774:-1
so has part: feature:592769-592774:-1:exon
so has part: feature:591712-592416:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:592769-592774:-1:exon

position:592769:-1
position: 592769
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:591712-592416:-1:exon

position:592416:-1
position: 592416
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YBR181C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LPG18
alternative label: RPS101
alternative label: RPS102
gene: RPS6B
locus tag: YBR181C
gene synonym: LPG18; RPS101; RPS102
experiment: EXISTENCE:curator inference:GO:0002181 cytoplasmic translation [PMID:6814480]
experiment: EXISTENCE:direct assay:GO:0003735 structural constituent of ribosome [PMID:6814480]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0022627 cytosolic small ribosomal subunit [PMID:6814480]
experiment: EXISTENCE:direct assay:GO:0032040 small-subunit processome [PMID:15590835]
experiment: EXISTENCE:genetic interaction:GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:16246728]
note: Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S6, no bacterial homolog; phosphorylated on S233 by Ypk3p in a TORC1-dependent manner, and on S232 in a TORC1/2-dependent manner by Ypk1/2/3p; RPS6B has a paralog, RPS6A, that arose from the whole genome duplication
codon start: 1
product: ribosomal 40S subunit protein S6B
translation: MKLNISYPVNGSQKTFEIDDEHRIRVFFDKRIGQEVDGEAVGDEFKGYVFKISGGNDKQGFPMKQGVLLPTRIKLLLTKNVSCYRPRRDGERKRKSVRGAIVGPDLAVLALVIVKKGEQELEGLTDTTVPKRLGPKRANNIRKFFGLSKEDDVRDFVIRREVTKGEKTYTKAPKIQRLVTPQRLQRKRHQRALKVRNAQAQREAAAEYAQLLAKRLSERKAEKAEIRKRRASSLKA
SIO_010081: YBR181C
subclass of: SO_0000673
so part of: YBR181C
location: complement(join(591712..592416,592769..592774))
location: region:591712-592774:-1
so has part: feature:592769-592774:-1:exon
so has part: feature:591712-592416:-1:exon

NP_009740.3
type: Protein
SIO_000068: ncbiprotein

S000000385
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:592769-592774:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:591712-592416:-1:exon

YBR182C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SMP1
locus tag: YBR182C
so part of: sequence
location: complement(<593506..>594864)
location: region:593506-594864:-1
so has part: feature:593506-594864:-1:exon
subclass of: SO_0000010

852480
type: Gene
SIO_000068: ncbigene

position:593506:-1
position: 593506
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:594864:-1
position: 594864
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:593506-594864:-1:exon

YBR182C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SMP1
locus tag: YBR182C
product: Smp1p
transcript id: NM_001178530.3
SIO_010081: YBR182C
subclass of: SO_0000673
so part of: YBR182C
location: complement(<593506..>594864)
location: region:593506-594864:-1
so has part: feature:593506-594864:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:593506-594864:-1:exon

YBR182C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SMP1
locus tag: YBR182C
experiment: EXISTENCE:curator inference:GO:0003700 DNA-binding transcription factor activity []
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:12482976]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:12482976]
experiment: EXISTENCE:direct assay:GO:0008301 DNA binding, bending [PMID:10064699]
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:9121433|PMID:19158363]
experiment: EXISTENCE:genetic interaction:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:12482976]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:12482976]
note: MADS-box transcription factor involved in osmotic stress response; SMP1 has a paralog, RLM1, that arose from the whole genome duplication
codon start: 1
product: Smp1p
translation: MGRRKIEIEPIKDDRNRTVTFIKRKAGLFKKAHELSVLCQVDIAVIILGSNNTFYEYSSVDMSNLLNVHQNNTDLPHNIIEPSDYGDYVKKPRVVLNERKRRRRRATVLQPASHSGSCTVSSQDSSSVQNNGNLSAPLASNDAGNAGVSTPLVHCHGAISRSGSNHSDCARNSADYQMLQGGLNSGGSFHANDYKESVDQQHVANEAIHRNFMNKRIRPDTHLLLSESNHSNYHNFYPSPYENLPKPSLPASLVGNIPSFQSQFVQVIPANSNPMGKGFNGTGDSESFEAKQKIHPTVAISNTLEGPAPVQAMVHHLHQLNSNRGKLSGKPYLKLNIPKATNDACQRSPAMYSGTASPKTDVQATPNQMLASNMSSPLSRSKFLGFKNNDMDDLYHNGRCGSTYVNNKTFFLKPPIGRPPKFPKSPSSSIVVFPSSVASSTLKSTSSTNSPD
SIO_010081: YBR182C
subclass of: SO_0000673
so part of: YBR182C
location: complement(593506..594864)
location: region:593506-594864:-1
so has part: feature:593506-594864:-1:exon

NP_009741.3
type: Protein
SIO_000068: ncbiprotein

S000000386
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:593506-594864:-1:exon

YBR182C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBR182C-A
so part of: sequence
location: complement(<595361..>595555)
location: region:595361-595555:-1
so has part: feature:595361-595555:-1:exon
subclass of: SO_0000010

1466446
type: Gene
SIO_000068: ncbigene

position:595361:-1
position: 595361
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:595555:-1
position: 595555
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:595361-595555:-1:exon

YBR182C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBR182C-A
product: uncharacterized protein
transcript id: NM_001184586.1
SIO_010081: YBR182C-A
subclass of: SO_0000673
so part of: YBR182C-A
location: complement(<595361..>595555)
location: region:595361-595555:-1
so has part: feature:595361-595555:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:595361-595555:-1:exon

YBR182C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBR182C-A
note: hypothetical protein; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
codon start: 1
product: uncharacterized protein
translation: MKIFTLYTMIQQYFFDNGGVYSIKNFYSAVPKEKMNIILVSLDCELQKLALKLSKKTSGTHTTH
SIO_010081: YBR182C-A
subclass of: SO_0000673
so part of: YBR182C-A
location: complement(595361..595555)
location: region:595361-595555:-1
so has part: feature:595361-595555:-1:exon

NP_878050.1
type: Protein
SIO_000068: ncbiprotein

S000028603
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:595361-595555:-1:exon

YBR183W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: YPC1
locus tag: YBR183W
so part of: sequence
location: <596115..>597065
location: region:596115-597065:1
so has part: feature:596115-597065:1:exon
subclass of: SO_0000010

852481
type: Gene
SIO_000068: ncbigene

position:596115:1
position: 596115
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:597065:1
position: 597065
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:596115-597065:1:exon

YBR183W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: YPC1
locus tag: YBR183W
product: phytoceramidase
transcript id: NM_001178531.1
SIO_010081: YBR183W
subclass of: SO_0000673
so part of: YBR183W
location: <596115..>597065
location: region:596115-597065:1
so has part: feature:596115-597065:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:596115-597065:1:exon

YBR183W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: YPC1
locus tag: YBR183W
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:10900202|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0032541 cortical endoplasmic reticulum [PMID:24866405]
experiment: EXISTENCE:genetic interaction:GO:0046513 ceramide biosynthetic process [PMID:11694577]
experiment: EXISTENCE:genetic interaction:GO:0050291 sphingosine N-acyltransferase activity [PMID:11694577]
experiment: EXISTENCE:mutant phenotype:GO:0046514 ceramide catabolic process [PMID:10702247]
experiment: EXISTENCE:mutant phenotype:GO:0050291 sphingosine N-acyltransferase activity [PMID:10702247]
experiment: EXISTENCE:mutant phenotype:GO:0070774 phytoceramidase activity [PMID:10702247|PMID:10900202]
note: Alkaline ceramidase; also has reverse (CoA-independent) ceramide synthase activity; catalyzes both breakdown and synthesis of phytoceramide; overexpression confers fumonisin B1 resistance; YPC1 has a paralog, YDC1, that arose from the whole genome duplication
codon start: 1
product: phytoceramidase
translation: MGIFRWNYPESSVPGVWGETTSTIDWCEENYVVSPYIAEWSNTLTNSVFILSAIYTTYSAYKNKLEKRFLLIGFGYGLVGVGSWLFHMTLKYRFQLLDELPMIYAMCIPTWSLVCEAKEALLNGDNHKKVPLFEQIFIGVIIGLAVTTASILYVIYKNVDIHQILFGVQIVVVAATAGSLTYRYVHDPLAKRNLKASMALGAILFLSGYISWLLDIHYCSFWVHVRRSILALPLGVLLEPHGWWHILTGMGIYFYIVSLEHLRVITLNVSCNYQFIWRWKVFPELIWKGRKPSTRYSLELFGPYVEDQSIEVKKEK
SIO_010081: YBR183W
subclass of: SO_0000673
so part of: YBR183W
location: 596115..597065
location: region:596115-597065:1
so has part: feature:596115-597065:1:exon

NP_009742.1
type: Protein
SIO_000068: ncbiprotein

S000000387
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:596115-597065:1:exon

YBR184W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBR184W
so part of: sequence
location: <597363..>598934
location: region:597363-598934:1
so has part: feature:597363-598934:1:exon
subclass of: SO_0000010

852482
type: Gene
SIO_000068: ncbigene

position:597363:1
position: 597363
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:598934:1
position: 598934
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:597363-598934:1:exon

YBR184W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBR184W
product: uncharacterized protein
transcript id: NM_001178532.3
SIO_010081: YBR184W
subclass of: SO_0000673
so part of: YBR184W
location: <597363..>598934
location: region:597363-598934:1
so has part: feature:597363-598934:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:597363-598934:1:exon

YBR184W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBR184W
note: hypothetical protein; YBR184W is not an essential gene
codon start: 1
product: uncharacterized protein
translation: MYQNNVLNAILASEKSNFQYDSGTILRNHKRPIITFNNNIEHTVSEPNNFTGYEEKEDLDIMDICPYYPKARMLADAIQHAKTSASENKMELSMKTIPCLKKENVHVEKGHDWSQLSTSRICKILEDIADKKNKTRRQSAPLQKTKYFPTNENQNTDIENQNWSQIPNEDICALIEKIASRRNKNRKRKNLSCSKVQEIQGNIDLPKKDVQEGDISDSSLFAAVRGTKKVSGYDYNSEDKIPNAIRLPYCKQILRLFSLLQMKRNDLIVTSENCNSGVFFSNFNYQLQVKSNCIANISSTLSFLPHHEITVYTSFILYPNVVDNIWECTRYAIQLLKSEAAQFTLLRDIYSGFTIILSNHRYHPKGFSADYCYSANELTLFLFVIRTGQKKVLYRSIPHNTAAIEKDSSFDTENRKRRSEEEVVLKCRKCSNNSLALKEISTYRLDSAEGFEKSQPLKDEAKLSDMNYVQGSISYNRTILTGLWKLFHRLCCKDRYRKTNLSETLFYDDSTERWVRMGELMHY
SIO_010081: YBR184W
subclass of: SO_0000673
so part of: YBR184W
location: 597363..598934
location: region:597363-598934:1
so has part: feature:597363-598934:1:exon

NP_009743.3
type: Protein
SIO_000068: ncbiprotein

S000000388
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:597363-598934:1:exon

YBR185C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MBA1
locus tag: YBR185C
so part of: sequence
location: complement(<599123..>599959)
location: region:599123-599959:-1
so has part: feature:599123-599959:-1:exon
subclass of: SO_0000010

852483
type: Gene
SIO_000068: ncbigene

position:599123:-1
position: 599123
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:599959:-1
position: 599959
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:599123-599959:-1:exon

YBR185C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MBA1
locus tag: YBR185C
product: Mba1p
transcript id: NM_001178533.3
SIO_010081: YBR185C
subclass of: SO_0000673
so part of: YBR185C
location: complement(<599123..>599959)
location: region:599123-599959:-1
so has part: feature:599123-599959:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:599123-599959:-1:exon

YBR185C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MBA1
locus tag: YBR185C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005743 mitochondrial inner membrane [PMID:11381092]
experiment: EXISTENCE:direct assay:GO:0007007 inner mitochondrial membrane organization [PMID:11381092]
experiment: EXISTENCE:direct assay:GO:0097177 mitochondrial ribosome binding [PMID:16601683]
experiment: EXISTENCE:genetic interaction:GO:0070131 positive regulation of mitochondrial translation [PMID:20427570]
experiment: EXISTENCE:mutant phenotype:GO:0032979 protein insertion into mitochondrial inner membrane from matrix [PMID:16601683]
note: Membrane-associated mitoribosome receptor; involved along with Dpi29p in the cotranslational insertion of nascent polypeptide chains into the inner mitochondrial membrane; associates with nascent polypeptide chains; interacts with Mdm38p and may recruit mRNA-specific translational activators to the mitoribosome; null mutant displays decreased tolerance to mistranslation-induced proteotoxic stress; localizes to the inner mitochondrial membrane
codon start: 1
product: Mba1p
translation: MSVLRSTCLFFPPRSLLISFNKRRLFSTSRLILNKESETTKKKDKSKQQDFNPRHLGVAAEIFIPSAYKNLPNVFAHPLIVANALIRRLYTFGLNSVQVALFRFQSGIKPSFLLWKNKAIETYINVNTSFAHKNLSDIKGLVSLWVQEALEARSRQLPGNATLDWQLIKFNAVPKLVSVQPIMIPGMPLEHLQLVYKFDTKQRLIKVNQQTKKTETLDRDVVDYIAFLCDATTNDMILMGSLFESKPNDKLPKSYEDDAKVAIHRMKVNGDIYRLPPS
SIO_010081: YBR185C
subclass of: SO_0000673
so part of: YBR185C
location: complement(599123..599959)
location: region:599123-599959:-1
so has part: feature:599123-599959:-1:exon

NP_009744.3
type: Protein
SIO_000068: ncbiprotein

S000000389
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:599123-599959:-1:exon

YBR186W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PCH2
locus tag: YBR186W
so part of: sequence
location: <600553..>602360
location: region:600553-602360:1
so has part: feature:600553-602360:1:exon
subclass of: SO_0000010

852484
type: Gene
SIO_000068: ncbigene

position:600553:1
position: 600553
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:602360:1
position: 602360
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:600553-602360:1:exon

YBR186W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PCH2
locus tag: YBR186W
product: Pch2p
transcript id: NM_001178534.1
SIO_010081: YBR186W
subclass of: SO_0000673
so part of: YBR186W
location: join(<600553..602103,602217..>602360)
location: region:600553-602360:1
so has part: feature:600553-602103:1:exon
so has part: feature:602217-602360:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:600553-602103:1:exon

position:602103:1
position: 602103
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:602217-602360:1:exon

position:602217:1
position: 602217
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YBR186W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PCH2
locus tag: YBR186W
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:11029058]
experiment: EXISTENCE:direct assay:GO:0016887 ATP hydrolysis activity [PMID:24367111]
experiment: EXISTENCE:genetic interaction:GO:0042138 meiotic DNA double-strand break formation [PMID:22745819]
experiment: EXISTENCE:mutant phenotype:GO:0007131 reciprocal meiotic recombination [PMID:18305165]
experiment: EXISTENCE:mutant phenotype:GO:0016887 ATP hydrolysis activity [PMID:24367111]
experiment: EXISTENCE:mutant phenotype:GO:0042138 meiotic DNA double-strand break formation [PMID:22745819]
experiment: EXISTENCE:mutant phenotype:GO:0051598 meiotic recombination checkpoint signaling [PMID:22072981]
note: Hexameric ring ATPase that remodels chromosome axis protein Hop1p; nucleolar component of the pachytene checkpoint, which prevents chromosome segregation when recombination and chromosome synapsis are defective; also represses meiotic interhomolog recombination in rDNA; required for meiotic double-stranded break formation
codon start: 1
product: Pch2p
translation: MSYIVDLQVRGSSLRVIKCMFREDEQISSLHSGSDSKQNSNKKLGEFLNLLKAVVKRKLESFPKDRLKTSIITGQELMREGQGSIEIKDPPTEAQQHLIRSLAKVLLHQFSSINGKVNTVNEGQDNLFLSLFVKKISIEQQSTSHVSIKLNFHEKINLGQHIDSILDSEETNESDTYHMGSVDEFIIYPFCCLEEQDELKNGSILSTEFDKIDLELDEDDGFEGETLNNCINSVGNFDIPLSKQTLNLVNISYLPGTTFEGQWESLYFGNNIKERLYSYATISLKIARFKQTGDSNQEDITTLITNNKLLLVHGPPGTGKTTLCKALCQKLSVRREFSDGSDTIDTNYKGIIIELSCARIFSKWFGESSKNISIVFKDIEELLKVNEGRGIFICLLIDEVEAIASSRTNLSSRNESTDGIRVVNTLLTQLDRLKKYHNFLALATSNLLDSLDDAFVDRADGVFYVGNPTAEGILHILKVCIEEMITSGIILFHARSTGVKFFNKYQDILRKIAIKCSTVDISGRTIRKLPLMCLSEYFRTFPVDDDEFVLALAMSARKLSAARK
SIO_010081: YBR186W
subclass of: SO_0000673
so part of: YBR186W
location: join(600553..602103,602217..602360)
location: region:600553-602360:1
so has part: feature:600553-602103:1:exon
so has part: feature:602217-602360:1:exon

NP_009745.2
type: Protein
SIO_000068: ncbiprotein

S000000390
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:600553-602103:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:602217-602360:1:exon

YBR187W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GDT1
locus tag: YBR187W
so part of: sequence
location: <602634..>603476
location: region:602634-603476:1
so has part: feature:602634-603476:1:exon
subclass of: SO_0000010

852485
type: Gene
SIO_000068: ncbigene

position:602634:1
position: 602634
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:603476:1
position: 603476
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:602634-603476:1:exon

YBR187W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GDT1
locus tag: YBR187W
product: putative ribosome biosynthesis protein GDT1
transcript id: NM_001178535.1
SIO_010081: YBR187W
subclass of: SO_0000673
so part of: YBR187W
location: <602634..>603476
location: region:602634-603476:1
so has part: feature:602634-603476:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:602634-603476:1:exon

YBR187W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GDT1
locus tag: YBR187W
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:23708375|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005384 manganese ion transmembrane transporter activity [PMID:29632074]
experiment: EXISTENCE:direct assay:GO:0005797 Golgi medial cisterna [PMID:23569283]
experiment: EXISTENCE:direct assay:GO:0005801 cis-Golgi network [PMID:23569283]
experiment: EXISTENCE:direct assay:GO:0015085 calcium ion transmembrane transporter activity [PMID:27075443]
experiment: EXISTENCE:direct assay:GO:0070588 calcium ion transmembrane transport [PMID:27075443]
experiment: EXISTENCE:direct assay:GO:0071421 manganese ion transmembrane transport [PMID:29632074]
experiment: EXISTENCE:genetic interaction:GO:0006874 cellular calcium ion homeostasis [PMID:23569283]
experiment: EXISTENCE:genetic interaction:GO:0030026 cellular manganese ion homeostasis [PMID:29632074]
experiment: EXISTENCE:mutant phenotype:GO:0006874 cellular calcium ion homeostasis [PMID:23569283]
experiment: EXISTENCE:mutant phenotype:GO:0030026 cellular manganese ion homeostasis [PMID:29632074]
experiment: EXISTENCE:mutant phenotype:GO:0032468 Golgi calcium ion homeostasis [PMID:27075443]
note: Calcium and manganese transporter with higher affinity for Ca2+; involved in Ca2+ and Mn2+ homeostasis; localizes to the cis- and medial-Golgi apparatus; GFP-fusion localizes to the vacuole; required for the Mn2+-dependent function of glycosylation enzymes; TMEM165, a human ortholog linked to Congenital Disorders of Glycosylation, functionally complements the null allele; expression pattern and physical interactions suggest a possible role in ribosome biogenesis; expression regulated by Gcr1p
codon start: 1
product: putative ribosome biosynthesis protein GDT1
translation: MGNMIKKASLIALLPLFTAAAAAATDAETSMESGSSSHLKSFLMSVSMIGLSEIGDKTFLIAALMAMRHKRVLVFSAAATSLAIMTILSGVVGHSAVAFLSERYTAFFAGILFLVFGYKLTMEGLEMSKDAGVEEEMAEVEEEIAIKDMNQDMDDVEKGGDTAYDKQLKNASIGKKIVHRIRELASFMFSPVWVQIFLMVFLGELGDRSQISIIAMATDSDYWYVIAGAVIGHAICSGLAVVGGKLLATRISIRTITLASSLLFFIFALMYIYQAFTTQD
SIO_010081: YBR187W
subclass of: SO_0000673
so part of: YBR187W
location: 602634..603476
location: region:602634-603476:1
so has part: feature:602634-603476:1:exon

NP_009746.1
type: Protein
SIO_000068: ncbiprotein

S000000391
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:602634-603476:1:exon

YBR188C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: NTC20
locus tag: YBR188C
so part of: sequence
location: complement(<603685..>604107)
location: region:603685-604107:-1
so has part: feature:603685-604107:-1:exon
subclass of: SO_0000010

852486
type: Gene
SIO_000068: ncbigene

position:603685:-1
position: 603685
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:604107:-1
position: 604107
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:603685-604107:-1:exon

YBR188C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: NTC20
locus tag: YBR188C
product: Ntc20p
transcript id: NM_001178536.3
SIO_010081: YBR188C
subclass of: SO_0000673
so part of: YBR188C
location: complement(<603685..>604107)
location: region:603685-604107:-1
so has part: feature:603685-604107:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:603685-604107:-1:exon

YBR188C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: NTC20
locus tag: YBR188C
experiment: EXISTENCE:curator inference:GO:0000384 first spliceosomal transesterification activity [PMID:11018040]
experiment: EXISTENCE:direct assay:GO:0000974 Prp19 complex [PMID:11018040]
experiment: EXISTENCE:direct assay:GO:0071006 U2-type catalytic step 1 spliceosome [PMID:11018040]
experiment: EXISTENCE:genetic interaction:GO:0000398 mRNA splicing, via spliceosome [PMID:11018040]
note: Member of the NineTeen Complex (NTC); this complex contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs
codon start: 1
product: Ntc20p
translation: MPSLRDLSLERDQELNQLRARINQLGKTGKEEANDFVGLNISNEPVYDTVIQTGQSSNATNSFVQETIQKTKQKESGQPYIIPQKNEHQRYIDKVCETSDLKAKLAPIMEVLEKKTNEKIKGIIRKRVLQEPDRDNDDSG
SIO_010081: YBR188C
subclass of: SO_0000673
so part of: YBR188C
location: complement(603685..604107)
location: region:603685-604107:-1
so has part: feature:603685-604107:-1:exon

NP_009747.3
type: Protein
SIO_000068: ncbiprotein

S000000392
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:603685-604107:-1:exon

YBR189W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RPS13A
alternative label: SUP46
gene: RPS9B
locus tag: YBR189W
gene synonym: RPS13A; SUP46
so part of: sequence
location: <604508..>605508
location: region:604508-605508:1
so has part: feature:604508-605508:1:exon
subclass of: SO_0000010

852487
type: Gene
SIO_000068: ncbigene

position:604508:1
position: 604508
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:605508:1
position: 605508
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:604508-605508:1:exon

YBR189W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RPS13A
alternative label: SUP46
gene: RPS9B
locus tag: YBR189W
gene synonym: RPS13A; SUP46
product: ribosomal 40S subunit protein S9B
transcript id: NM_001178537.3
SIO_010081: YBR189W
subclass of: SO_0000673
so part of: YBR189W
location: join(<604508..604514,604928..>605508)
location: region:604508-605508:1
so has part: feature:604508-604514:1:exon
so has part: feature:604928-605508:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:604508-604514:1:exon

position:604514:1
position: 604514
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:604928-605508:1:exon

position:604928:1
position: 604928
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YBR189W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RPS13A
alternative label: SUP46
gene: RPS9B
locus tag: YBR189W
gene synonym: RPS13A; SUP46
experiment: EXISTENCE:direct assay:GO:0003735 structural constituent of ribosome [PMID:6814480]
experiment: EXISTENCE:direct assay:GO:0022627 cytosolic small ribosomal subunit [PMID:6814480]
experiment: EXISTENCE:direct assay:GO:0030686 90S preribosome [PMID:12150911]
experiment: EXISTENCE:direct assay:GO:0032040 small-subunit processome [PMID:15590835]
experiment: EXISTENCE:genetic interaction:GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:16246728]
experiment: EXISTENCE:mutant phenotype:GO:0045903 positive regulation of translational fidelity [PMID:3522920|PMID:6273576|PMID:7031258|PMID:7031259]
note: Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S9 and bacterial S4; RPS9B has a paralog, RPS9A, that arose from the whole genome duplication
codon start: 1
product: ribosomal 40S subunit protein S9B
translation: MPRAPRTYSKTYSTPKRPYESSRLDAELKLAGEFGLKNKREIYRISFQLSKIRRAARDLLTRDEKDPKRLFEGNALIRRLVRVGVLSEDKKKLDYVLALKVEDFLERRLQTQVYKLGLAKSVHHARVLITQRHIAVGKQIVNIPSFMVRLDSEKHIDFAPTSPFGGARPGRVARRNAARKAEASGEAAEEAEDEE
SIO_010081: YBR189W
subclass of: SO_0000673
so part of: YBR189W
location: join(604508..604514,604928..605508)
location: region:604508-605508:1
so has part: feature:604508-604514:1:exon
so has part: feature:604928-605508:1:exon

NP_009748.3
type: Protein
SIO_000068: ncbiprotein

S000000393
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:604508-604514:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:604928-605508:1:exon

YBR191W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: URP1
gene: RPL21A
locus tag: YBR191W
gene synonym: URP1
so part of: sequence
location: <606270..>607140
location: region:606270-607140:1
so has part: feature:606270-607140:1:exon
subclass of: SO_0000010

852489
type: Gene
SIO_000068: ncbigene

position:606270:1
position: 606270
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:607140:1
position: 607140
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:606270-607140:1:exon

YBR191W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: URP1
gene: RPL21A
locus tag: YBR191W
gene synonym: URP1
product: ribosomal 60S subunit protein L21A
transcript id: NM_001178539.1
SIO_010081: YBR191W
subclass of: SO_0000673
so part of: YBR191W
location: join(<606270..606280,606669..>607140)
location: region:606270-607140:1
so has part: feature:606270-606280:1:exon
so has part: feature:606669-607140:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:606270-606280:1:exon

position:606280:1
position: 606280
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:606669-607140:1:exon

position:606669:1
position: 606669
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YBR191W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: URP1
gene: RPL21A
locus tag: YBR191W
gene synonym: URP1
experiment: EXISTENCE:curator inference:GO:0002181 cytoplasmic translation [PMID:11983894]
experiment: EXISTENCE:curator inference:GO:0003735 structural constituent of ribosome [PMID:11983894]
experiment: EXISTENCE:direct assay:GO:0022625 cytosolic large ribosomal subunit [PMID:11983894]
note: Ribosomal 60S subunit protein L21A; homologous to mammalian ribosomal protein L21, no bacterial homolog; RPL21A has a paralog, RPL21B, that arose from the whole genome duplication
codon start: 1
product: ribosomal 60S subunit protein L21A
translation: MGKSHGYRSRTRYMFQRDFRKHGAVHLSTYLKVYKVGDIVDIKANGSIQKGMPHKFYQGKTGVVYNVTKSSVGVIINKMVGNRYLEKRLNLRVEHIKHSKCRQEFLERVKANAAKRAEAKAQGVAVQLKRQPAQPRESRIVSTEGNVPQTLAPVPYETFI
SIO_010081: YBR191W
subclass of: SO_0000673
so part of: YBR191W
location: join(606270..606280,606669..607140)
location: region:606270-607140:1
so has part: feature:606270-606280:1:exon
so has part: feature:606669-607140:1:exon

NP_009750.1
type: Protein
SIO_000068: ncbiprotein

S000000395
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:606270-606280:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:606669-607140:1:exon

YBR192W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PYT1
gene: RIM2
locus tag: YBR192W
gene synonym: PYT1
so part of: sequence
location: <607652..>608785
location: region:607652-608785:1
so has part: feature:607652-608785:1:exon
subclass of: SO_0000010

852491
type: Gene
SIO_000068: ncbigene

position:607652:1
position: 607652
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:608785:1
position: 608785
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:607652-608785:1:exon

YBR192W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PYT1
gene: RIM2
locus tag: YBR192W
gene synonym: PYT1
product: Rim2p
transcript id: NM_001178540.1
SIO_010081: YBR192W
subclass of: SO_0000673
so part of: YBR192W
location: <607652..>608785
location: region:607652-608785:1
so has part: feature:607652-608785:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:607652-608785:1:exon

YBR192W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PYT1
gene: RIM2
locus tag: YBR192W
gene synonym: PYT1
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:7891656|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0006864 pyrimidine nucleotide transport [PMID:16194150]
experiment: EXISTENCE:direct assay:GO:0015218 pyrimidine nucleotide transmembrane transporter activity [PMID:16194150]
experiment: EXISTENCE:direct assay:GO:0030001 metal ion transport [PMID:23800229]
experiment: EXISTENCE:direct assay:GO:0055085 transmembrane transport [PMID:16194150]
experiment: EXISTENCE:mutant phenotype:GO:0000002 mitochondrial genome maintenance [PMID:7891656]
note: Mitochondrial pyrimidine nucleotide transporter; imports pyrimidine nucleoside triphosphates and exports pyrimidine nucleoside monophosphates; member of the mitochondrial carrier family
codon start: 1
product: Rim2p
translation: MPKKSIEEWEEDAIESVPYLASDEKGSNYKEATQIPLNLKQSEIENHPTVKPWVHFVAGGIGGMAGAVVTCPFDLVKTRLQSDIFLKAYKSQAVNISKGSTRPKSINYVIQAGTHFKETLGIIGNVYKQEGFRSLFKGLGPNLVGVIPARSINFFTYGTTKDMYAKAFNNGQETPMIHLMAAATAGWATATATNPIWLIKTRVQLDKAGKTSVRQYKNSWDCLKSVIRNEGFTGLYKGLSASYLGSVEGILQWLLYEQMKRLIKERSIEKFGYQAEGTKSTSEKVKEWCQRSGSAGLAKFVASIATYPHEVVRTRLRQTPKENGKRKYTGLVQSFKVIIKEEGLFSMYSGLTPHLMRTVPNSIIMFGTWEIVIRLLS
SIO_010081: YBR192W
subclass of: SO_0000673
so part of: YBR192W
location: 607652..608785
location: region:607652-608785:1
so has part: feature:607652-608785:1:exon

NP_009751.1
type: Protein
SIO_000068: ncbiprotein

S000000396
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:607652-608785:1:exon

YBR193C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MED8
locus tag: YBR193C
so part of: sequence
location: complement(<609082..>609753)
location: region:609082-609753:-1
so has part: feature:609082-609753:-1:exon
subclass of: SO_0000010

852492
type: Gene
SIO_000068: ncbigene

position:609082:-1
position: 609082
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:609753:-1
position: 609753
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:609082-609753:-1:exon

YBR193C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MED8
locus tag: YBR193C
product: Med8p
transcript id: NM_001178541.3
SIO_010081: YBR193C
subclass of: SO_0000673
so part of: YBR193C
location: complement(<609082..>609753)
location: region:609082-609753:-1
so has part: feature:609082-609753:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:609082-609753:-1:exon

YBR193C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MED8
locus tag: YBR193C
experiment: EXISTENCE:direct assay:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:15705057]
experiment: EXISTENCE:direct assay:GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding [PMID:12054864]
experiment: EXISTENCE:direct assay:GO:0017025 TBP-class protein binding [PMID:16964259]
experiment: EXISTENCE:direct assay:GO:0070847 core mediator complex [PMID:9891034]
experiment: EXISTENCE:mutant phenotype:GO:0030674 protein-macromolecule adaptor activity [PMID:18381891]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:18381891]
experiment: EXISTENCE:physical interaction:GO:0003714 transcription corepressor activity [PMID:16528100]
note: Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation
codon start: 1
product: Med8p
translation: MSQSTASLVPEGNQGSLQEDVSFDFNGVPGQALDAVRMRLAQLTHSLRRIRDEMSKAELPQWYTLQSQLNVTLSQLVSVTSTLQHFQETLDSTVVYPLPKFPTTSHESLVTTLLRKKNIPEVDEWMKYVRETSGVTTALLKDEEIEKLLQQDREITNWARTTFRNEYGKHDFKNEESLSEEHASLLVRDSKPSKPFNVDDVLKFTFTGEKPIITGSTSTSSSN
SIO_010081: YBR193C
subclass of: SO_0000673
so part of: YBR193C
location: complement(609082..609753)
location: region:609082-609753:-1
so has part: feature:609082-609753:-1:exon

NP_009752.3
type: Protein
SIO_000068: ncbiprotein

S000000397
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:609082-609753:-1:exon

YBR194W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SOY1
gene: AIM4
locus tag: YBR194W
gene synonym: SOY1
so part of: sequence
location: <610038..>610409
location: region:610038-610409:1
so has part: feature:610038-610409:1:exon
subclass of: SO_0000010

852493
type: Gene
SIO_000068: ncbigene

position:610038:1
position: 610038
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:610409:1
position: 610409
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:610038-610409:1:exon

YBR194W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SOY1
gene: AIM4
locus tag: YBR194W
gene synonym: SOY1
product: Aim4p
transcript id: NM_001178542.3
SIO_010081: YBR194W
subclass of: SO_0000673
so part of: YBR194W
location: <610038..>610409
location: region:610038-610409:1
so has part: feature:610038-610409:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:610038-610409:1:exon

YBR194W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SOY1
gene: AIM4
locus tag: YBR194W
gene synonym: SOY1
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:10684247]
note: Protein proposed to be associated with the nuclear pore complex; null mutant is viable, displays elevated frequency of mitochondrial genome loss and is sensitive to freeze-thaw stress
codon start: 1
product: Aim4p
translation: MDQKKDPSNNLTERRVSKVQRPNKKKVRNQVESLSRNLERNKEGQLLQTVSKGHLEADSGHSLGREKENGELGIRSIFYDKDWNPRGTAPSHYRNIPYNPATFKRRTEVQARLGNLENIKIPK
SIO_010081: YBR194W
subclass of: SO_0000673
so part of: YBR194W
location: 610038..610409
location: region:610038-610409:1
so has part: feature:610038-610409:1:exon

NP_009753.3
type: Protein
SIO_000068: ncbiprotein

S000000398
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:610038-610409:1:exon

YBR195C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CAC3
gene: MSI1
locus tag: YBR195C
gene synonym: CAC3
so part of: sequence
location: complement(<610614..>611882)
location: region:610614-611882:-1
so has part: feature:610614-611882:-1:exon
subclass of: SO_0000010

852494
type: Gene
SIO_000068: ncbigene

position:610614:-1
position: 610614
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:611882:-1
position: 611882
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:610614-611882:-1:exon

YBR195C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CAC3
gene: MSI1
locus tag: YBR195C
gene synonym: CAC3
product: Msi1p
transcript id: NM_001178543.1
SIO_010081: YBR195C
subclass of: SO_0000673
so part of: YBR195C
location: complement(<610614..>611882)
location: region:610614-611882:-1
so has part: feature:610614-611882:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:610614-611882:-1:exon

YBR195C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CAC3
gene: MSI1
locus tag: YBR195C
gene synonym: CAC3
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:11238915]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11238915]
experiment: EXISTENCE:direct assay:GO:0006335 DNA replication-dependent chromatin assembly [PMID:9030687]
experiment: EXISTENCE:direct assay:GO:0033186 CAF-1 complex [PMID:9030687]
experiment: EXISTENCE:direct assay:GO:0042393 histone binding [PMID:16503640]
note: Subunit of chromatin assembly factor I (CAF-1); chromatin assembly by CAF-1 affects multiple processes including silencing at telomeres, mating type loci, and rDNA; maintenance of kinetochore structure; deactivation of DNA damage checkpoint after DNA repair; chromatin dynamics during transcription; and repression of divergent noncoding transcription; Msi1p localizes to nucleus and cytoplasm and independently regulates the RAS/cAMP pathway via sequestration of Npr1p kinase
codon start: 1
product: Msi1p
translation: MNQCAKDITHEASSIPIDLQERYSHWKKNTKLLYDYLNTNSTKWPSLTCQFFPDLDTTSDEHRILLSSFTSSQKPEDETIYISKISTLGHIKWSSLNNFDMDEMEFKPENSTRFPSKHLVNDISIFFPNGECNRARYLPQNPDIIAGASSDGAIYIFDRTKHGSTRIRQSKISHPFETKLFGSHGVIQDVEAMDTSSADINEATSLAWNLQQEALLLSSHSNGQVQVWDIKQYSHENPIIDLPLVSINSDGTAVNDVTWMPTHDSLFAACTEGNAVSLLDLRTKKEKLQSNREKHDGGVNSCRFNYKNSLILASADSNGRLNLWDIRNMNKSPIATMEHGTSVSTLEWSPNFDTVLATAGQEDGLVKLWDTSCEETIFTHGGHMLGVNDISWDAHDPWLMCSVANDNSVHIWKPAGNLVGHS
SIO_010081: YBR195C
subclass of: SO_0000673
so part of: YBR195C
location: complement(610614..611882)
location: region:610614-611882:-1
so has part: feature:610614-611882:-1:exon

NP_009754.1
type: Protein
SIO_000068: ncbiprotein

S000000399
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:610614-611882:-1:exon

YBR196C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CDC30
gene: PGI1
locus tag: YBR196C
gene synonym: CDC30
so part of: sequence
location: complement(<612236..>613900)
location: region:612236-613900:-1
so has part: feature:612236-613900:-1:exon
subclass of: SO_0000010

852495
type: Gene
SIO_000068: ncbigene

position:612236:-1
position: 612236
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:613900:-1
position: 613900
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:612236-613900:-1:exon

YBR196C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CDC30
gene: PGI1
locus tag: YBR196C
gene synonym: CDC30
product: glucose-6-phosphate isomerase
transcript id: NM_001178544.1
SIO_010081: YBR196C
subclass of: SO_0000673
so part of: YBR196C
location: complement(<612236..>613900)
location: region:612236-613900:-1
so has part: feature:612236-613900:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:612236-613900:-1:exon

YBR196C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CDC30
gene: PGI1
locus tag: YBR196C
gene synonym: CDC30
EC number: 5.3.1.9
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16962558|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:16622836]
experiment: EXISTENCE:mutant phenotype:GO:0004347 glucose-6-phosphate isomerase activity [PMID:3007940]
experiment: EXISTENCE:mutant phenotype:GO:0006094 gluconeogenesis [PMID:3020369]
experiment: EXISTENCE:mutant phenotype:GO:0006096 glycolytic process [PMID:3007940]
note: Glycolytic enzyme phosphoglucose isomerase; catalyzes the interconversion of glucose-6-phosphate and fructose-6-phosphate; required for cell cycle progression and completion of the gluconeogenic events of sporulation
codon start: 1
product: glucose-6-phosphate isomerase
translation: MSNNSFTNFKLATELPAWSKLQKIYESQGKTLSVKQEFQKDAKRFEKLNKTFTNYDGSKILFDYSKNLVNDEIIAALIELAKEANVTGLRDAMFKGEHINSTEDRAVYHVALRNRANKPMYVDGVNVAPEVDSVLKHMKEFSEQVRSGEWKGYTGKKITDVVNIGIGGSDLGPVMVTEALKHYAGVLDVHFVSNIDGTHIAETLKVVDPETTLFLIASKTFTTAETITNANTAKNWFLSKTGNDPSHIAKHFAALSTNETEVAKFGIDTKNMFGFESWVGGRYSVWSAIGLSVALYIGYDNFEAFLKGAEAVDNHFTQTPLEDNIPLLGGLLSVWYNNFFGAQTHLVAPFDQYLHRFPAYLQQLSMESNGKSVTRGNVFTDYSTGSILFGEPATNAQHSFFQLVHQGTKLIPSDFILAAQSHNPIENKLHQKMLASNFFAQAEALMVGKDEEQVKAEGATGGLVPHKVFSGNRPTTSILAQKITPATLGALIAYYEHVTFTEGAIWNINSFDQWGVELGKVLAKVIGKELDNSSTISTHDASTNGLINQFKEWM
SIO_010081: YBR196C
subclass of: SO_0000673
so part of: YBR196C
location: complement(612236..613900)
location: region:612236-613900:-1
so has part: feature:612236-613900:-1:exon

NP_009755.1
type: Protein
SIO_000068: ncbiprotein

S000000400
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:612236-613900:-1:exon

YBR196C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBR196C-A
so part of: sequence
location: complement(<614024..>614173)
location: region:614024-614173:-1
so has part: feature:614024-614173:-1:exon
subclass of: SO_0000010

1466447
type: Gene
SIO_000068: ncbigene

position:614024:-1
position: 614024
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:614173:-1
position: 614173
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:614024-614173:-1:exon

YBR196C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBR196C-A
product: uncharacterized protein
transcript id: NM_001184541.3
SIO_010081: YBR196C-A
subclass of: SO_0000673
so part of: YBR196C-A
location: complement(<614024..>614173)
location: region:614024-614173:-1
so has part: feature:614024-614173:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:614024-614173:-1:exon

YBR196C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBR196C-A
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:32034123]
note: hypothetical protein; identified by fungal homology and RT-PCR; ORF emerged de novo in thymine-rich ancestral non-genic region, accumulated substantial changes under positive selection, and progressively increased its transmembrane propensity to give rise to a protein that integrates into the endoplasmic reticulum (ER) membrane while retaining potential for adaptive change
codon start: 1
product: uncharacterized protein
translation: MSRVYIYPLTVFYFFAIEMSVFCYYNWFYRRNFPYLFRPIFPFLIVLIS
SIO_010081: YBR196C-A
subclass of: SO_0000673
so part of: YBR196C-A
location: complement(614024..614173)
location: region:614024-614173:-1
so has part: feature:614024-614173:-1:exon

NP_878051.3
type: Protein
SIO_000068: ncbiprotein

S000028534
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:614024-614173:-1:exon

YBR196C-B
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBR196C-B
so part of: sequence
location: complement(<614526..>614630)
location: region:614526-614630:-1
so has part: feature:614526-614630:-1:exon
subclass of: SO_0000010

1466448
type: Gene
SIO_000068: ncbigene

position:614526:-1
position: 614526
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:614630:-1
position: 614630
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:614526-614630:-1:exon

YBR196C-B
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBR196C-B
product: uncharacterized protein
transcript id: NM_001184643.3
SIO_010081: YBR196C-B
subclass of: SO_0000673
so part of: YBR196C-B
location: complement(<614526..>614630)
location: region:614526-614630:-1
so has part: feature:614526-614630:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:614526-614630:-1:exon

YBR196C-B
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBR196C-B
note: hypothetical protein; identified by expression profiling and mass spectrometry
codon start: 1
product: uncharacterized protein
translation: MWVVLSKEKILLKKAYYAKTILFSALVLRGVRGE
SIO_010081: YBR196C-B
subclass of: SO_0000673
so part of: YBR196C-B
location: complement(614526..614630)
location: region:614526-614630:-1
so has part: feature:614526-614630:-1:exon

NP_878052.3
type: Protein
SIO_000068: ncbiprotein

S000028816
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:614526-614630:-1:exon

YBR197C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBR197C
so part of: sequence
location: complement(<615203..>615856)
location: region:615203-615856:-1
so has part: feature:615203-615856:-1:exon
subclass of: SO_0000010

852496
type: Gene
SIO_000068: ncbigene

position:615203:-1
position: 615203
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:615856:-1
position: 615856
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:615203-615856:-1:exon

YBR197C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBR197C
product: uncharacterized protein
transcript id: NM_001178545.1
SIO_010081: YBR197C
subclass of: SO_0000673
so part of: YBR197C
location: complement(<615203..>615856)
location: region:615203-615856:-1
so has part: feature:615203-615856:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:615203-615856:-1:exon

YBR197C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBR197C
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095|PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095|PMID:22842922]
note: hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YBR197C is not an essential gene; relative distribution to the nucleus increases upon DNA replication stress; YBR197C has a paralog, YPL077C, that arose from the whole genome duplication
codon start: 1
product: uncharacterized protein
translation: MGVKQTPPVQVKVSDADSTNRRKSSSQEGNPQLVQLKAKSDKDKRKGSSDSTASIMGSSNALPTKNLTTPPALNPLTTSISRGNTAYERSVNGSRITMHSNLAPTETQDVSWSEIDTLDDVKKMAKEPIVNDGFPRDFESNLTQMRKSHAQLLRLMRERNQRLKYAKLRSPPHKDQHNSATNKDQEPDEVLHDPEIALDGEKYVSQVVDTIKDVHRC
SIO_010081: YBR197C
subclass of: SO_0000673
so part of: YBR197C
location: complement(615203..615856)
location: region:615203-615856:-1
so has part: feature:615203-615856:-1:exon

NP_009756.1
type: Protein
SIO_000068: ncbiprotein

S000000401
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:615203-615856:-1:exon

YBR198C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: TAF90
gene: TAF5
locus tag: YBR198C
gene synonym: TAF90
so part of: sequence
location: complement(<616127..>618523)
location: region:616127-618523:-1
so has part: feature:616127-618523:-1:exon
subclass of: SO_0000010

852497
type: Gene
SIO_000068: ncbigene

position:616127:-1
position: 616127
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:618523:-1
position: 618523
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:616127-618523:-1:exon

YBR198C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: TAF90
gene: TAF5
locus tag: YBR198C
gene synonym: TAF90
product: chromatin modification protein
transcript id: NM_001178546.1
SIO_010081: YBR198C
subclass of: SO_0000673
so part of: YBR198C
location: complement(<616127..>618523)
location: region:616127-618523:-1
so has part: feature:616127-618523:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:616127-618523:-1:exon

YBR198C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: TAF90
gene: TAF5
locus tag: YBR198C
gene synonym: TAF90
experiment: EXISTENCE:direct assay:GO:0000124 SAGA complex [PMID:9674426]
experiment: EXISTENCE:direct assay:GO:0003682 chromatin binding [PMID:12600943]
experiment: EXISTENCE:direct assay:GO:0005669 transcription factor TFIID complex [PMID:10788514|PMID:15448131]
experiment: EXISTENCE:direct assay:GO:0006325 chromatin organization [PMID:9674426]
experiment: EXISTENCE:direct assay:GO:0006366 transcription by RNA polymerase II [PMID:12138208|PMID:15448131]
experiment: EXISTENCE:direct assay:GO:0043130 ubiquitin binding [PMID:21070969]
experiment: EXISTENCE:direct assay:GO:0046695 SLIK (SAGA-like) complex [PMID:12446794]
experiment: EXISTENCE:mutant phenotype:GO:0060090 molecular adaptor activity [PMID:11585915]
note: Subunit (90 kDa) of TFIID and SAGA complexes; involved in RNA polymerase II transcription initiation and in chromatin modification
codon start: 1
product: chromatin modification protein
translation: MSQKQSTNQNQNGTHQPQPVKNQRTNNAAGANSGQQPQQQSQGQSQQQGRSNGPFSASDLNRIVLEYLNKKGYHRTEAMLRAESGRTLTPQNKQSPANTKTGKFPEQSSIPPNPGKTAKPISNPTNLSSKRDAEGGIVSSGRLEGLNAPENYIRAYSMLKNWVDSSLEIYKPELSYIMYPIFIYLFLNLVAKNPVYARRFFDRFSPDFKDFHGSEINRLFSVNSIDHIKENEVASAFQSHKYRITMSKTTLNLLLYFLNENESIGGSLIISVINQHLDPNIVESVTAREKLADGIKVLSDSENGNGKQNLEMNSVPVKLGPFPKDEEFVKEIETELKIKDDQEKQLNQQTAGDNYSGANNRTLLQEYKAMNNEKFKDNTGDDDKDKIKDKIAKDEEKKESELKVDGEKKDSNLSSPARDILPLPPKTALDLKLEIQKVKESRDAIKLDNLQLALPSVCMYTFQNTNKDMSCLDFSDDCRIAAAGFQDSYIKIWSLDGSSLNNPNIALNNNDKDEDPTCKTLVGHSGTVYSTSFSPDNKYLLSGSEDKTVRLWSMDTHTALVSYKGHNHPVWDVSFSPLGHYFATASHDQTARLWSCDHIYPLRIFAGHLNDVDCVSFHPNGCYVFTGSSDKTCRMWDVSTGDSVRLFLGHTAPVISIAVCPDGRWLSTGSEDGIINVWDIGTGKRLKQMRGHGKNAIYSLSYSKEGNVLISGGADHTVRVWDLKKATTEPSAEPDEPFIGYLGDVTASINQDIKEYGRRRTVIPTSDLVASFYTKKTPVFKVKFSRSNLALAGGAFRP
SIO_010081: YBR198C
subclass of: SO_0000673
so part of: YBR198C
location: complement(616127..618523)
location: region:616127-618523:-1
so has part: feature:616127-618523:-1:exon

NP_009757.1
type: Protein
SIO_000068: ncbiprotein

S000000402
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:616127-618523:-1:exon

YBR199W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: KTR4
locus tag: YBR199W
so part of: sequence
location: <618909..>620303
location: region:618909-620303:1
so has part: feature:618909-620303:1:exon
subclass of: SO_0000010

852498
type: Gene
SIO_000068: ncbigene

position:618909:1
position: 618909
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:620303:1
position: 620303
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:618909-620303:1:exon

YBR199W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: KTR4
locus tag: YBR199W
product: putative mannosyltransferase
transcript id: NM_001178547.3
SIO_010081: YBR199W
subclass of: SO_0000673
so part of: YBR199W
location: <618909..>620303
location: region:618909-620303:1
so has part: feature:618909-620303:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:618909-620303:1:exon

YBR199W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: KTR4
locus tag: YBR199W
experiment: EXISTENCE:direct assay:GO:0000030 mannosyltransferase activity [PMID:26296208]
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:26928762]
note: Glycosyltransferase involved in protein glycosylation; transfers GDP-mannose to methyl-alpha-mannoside in vitro; member of the KRE2/MNT1 mannosyltransferase family of type II membrane proteins with a short cytoplasmic N-terminus, a membrane-spanning region and a highly conserved catalytic lumenal domain
codon start: 1
product: putative mannosyltransferase
translation: MRFLSKRILKPVLSVIILISIAVTVVLYFLTANENYLQAVKDSAKSQYASLRESYKSITGKTESADELPDHDAEVLDSIMDRLHEPLYEKDTFDPNEVLAENKQLYEEFLLQEISEPKVDNLVRSGDPLAGKAKGTILSLVRNSDLEDIISSIQQLEEEYNKNFGYPYTFLNDEEFTDEFKDGIKSILPKDRVVEFGTIGPDNWNMPDSIDRERYDQEMDKMSKENIQYAEVESYHNMCRFYSKEFYHHPLLSKYKYVWRLEPNVNFYCKINYDVFQFMNKNDKIYGFVLNLYDSPQTIETLWTSTMDFVEEHPNYLNVNGAFAWLKDNSQNPKNYDYTQGYSTCHFWTNFEIVDLDFLRSEPYEKYMQYLEEKGGFYYERWGDAPVRSLALALFADKSSIHWFRDIGYHHTPYTNCPTCPADSDRCNGNCVPGKFTPWSDLDNQNCQATWIRHSMSEEELEMY
SIO_010081: YBR199W
subclass of: SO_0000673
so part of: YBR199W
location: 618909..620303
location: region:618909-620303:1
so has part: feature:618909-620303:1:exon

NP_009758.3
type: Protein
SIO_000068: ncbiprotein

S000000403
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:618909-620303:1:exon

YBR200W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SRO1
gene: BEM1
locus tag: YBR200W
gene synonym: SRO1
so part of: sequence
location: <620872..>622527
location: region:620872-622527:1
so has part: feature:620872-622527:1:exon
subclass of: SO_0000010

852499
type: Gene
SIO_000068: ncbigene

position:620872:1
position: 620872
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:622527:1
position: 622527
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:620872-622527:1:exon

YBR200W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SRO1
gene: BEM1
locus tag: YBR200W
gene synonym: SRO1
product: phosphatidylinositol-3-phosphate-binding protein BEM1
transcript id: NM_001178548.3
SIO_010081: YBR200W
subclass of: SO_0000673
so part of: YBR200W
location: <620872..>622527
location: region:620872-622527:1
so has part: feature:620872-622527:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:620872-622527:1:exon

YBR200W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SRO1
gene: BEM1
locus tag: YBR200W
gene synonym: SRO1
experiment: EXISTENCE:direct assay:GO:0000131 incipient cellular bud site [PMID:9128251|PMID:11927541]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11927541]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:24390141]
experiment: EXISTENCE:direct assay:GO:0005934 cellular bud tip [PMID:11927541]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:11927541]
experiment: EXISTENCE:direct assay:GO:0005938 cell cortex [PMID:11927541]
experiment: EXISTENCE:direct assay:GO:0030427 site of polarized growth [PMID:23613772]
experiment: EXISTENCE:direct assay:GO:0032266 phosphatidylinositol-3-phosphate binding [PMID:11557775]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:19053807]
experiment: EXISTENCE:mutant phenotype:GO:0000753 cell morphogenesis involved in conjugation with cellular fusion [PMID:10087263]
experiment: EXISTENCE:mutant phenotype:GO:0045185 maintenance of protein location [PMID:11927541]
experiment: EXISTENCE:mutant phenotype:GO:0061191 positive regulation of vacuole fusion, non-autophagic [PMID:16854988]
experiment: EXISTENCE:physical interaction:GO:0060090 molecular adaptor activity [PMID:11113154]
note: Protein containing SH3-domains; involved in establishing cell polarity and morphogenesis; functions as a scaffold protein for complexes that include Cdc24p, Ste5p, Ste20p, and Rsr1p
codon start: 1
product: phosphatidylinositol-3-phosphate-binding protein BEM1
translation: MLKNFKLSKRDSNGSKGRITSADISTPSHDNGSVIKHIKTVPVRYLSSSSTPVKSQRDSSPKNRHNSKDITSPEKVIKAKYSYQAQTSKELSFMEGEFFYVSGDEKDWYKASNPSTGKEGVVPKTYFEVFDRTKPSSVNGSNSSSRKVTNDSLNMGSLYAIVLYDFKAEKADELTTYVGENLFICAHHNCEWFIAKPIGRLGGPGLVPVGFVSIIDIATGYATGNDVIEDIKSVNLPTVQEWKSNIARYKASNISLGSVEQQQQQSITKPQNKSAKLVDGELLVKASVESFGLEDEKYWFLVCCELSNGKTRQLKRYYQDFYDLQVQLLDAFPAEAGKLRDAGGQWSKRIMPYIPGPVPYVTNSITKKRKEDLNIYVADLVNLPDYISRSEMVHSLFVVLNNGFDREFERDENQNNIKTLQENDTATFATASQTSNFASTNQDNTLTGEDLKLNKKLSDLSLSGSKQAPAQSTSGLKTTKIKFYYKDDIFALMLKGDTTYKELRSKIAPRIDTDNFKLQTKLFDGSGEEIKTDSQVSNIIQAKLKISVHDI
SIO_010081: YBR200W
subclass of: SO_0000673
so part of: YBR200W
location: 620872..622527
location: region:620872-622527:1
so has part: feature:620872-622527:1:exon

NP_009759.3
type: Protein
SIO_000068: ncbiprotein

S000000404
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:620872-622527:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS220; Autonomously Replicating Sequence
so part of: sequence
location: 622671..622939
location: region:622671-622939:1
so has part: feature:622671-622939:1:region

S000118351
type: SGD
SIO_000068: sgd

position:622671:1
position: 622671
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:622939:1
position: 622939
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:622671-622939:1:region

YBR200W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBR200W-A
so part of: sequence
location: <622983..>623147
location: region:622983-623147:1
so has part: feature:622983-623147:1:exon
subclass of: SO_0000010

1466449
type: Gene
SIO_000068: ncbigene

position:622983:1
position: 622983
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:623147:1
position: 623147
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:622983-623147:1:exon

YBR200W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBR200W-A
product: uncharacterized protein
transcript id: NM_001184542.1
SIO_010081: YBR200W-A
subclass of: SO_0000673
so part of: YBR200W-A
location: <622983..>623147
location: region:622983-623147:1
so has part: feature:622983-623147:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:622983-623147:1:exon

YBR200W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBR200W-A
note: hypothetical protein; identified by fungal homology and RT-PCR
codon start: 1
product: uncharacterized protein
translation: MLLCFHMCQRIMWLPFDLMKWRRFHCGAVLVGTLSLRNRSPKILSLYFISDRTG
SIO_010081: YBR200W-A
subclass of: SO_0000673
so part of: YBR200W-A
location: 622983..623147
location: region:622983-623147:1
so has part: feature:622983-623147:1:exon

NP_878053.1
type: Protein
SIO_000068: ncbiprotein

S000028535
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:622983-623147:1:exon

YBR201W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: DER1
locus tag: YBR201W
so part of: sequence
location: <623576..>624211
location: region:623576-624211:1
so has part: feature:623576-624211:1:exon
subclass of: SO_0000010

852500
type: Gene
SIO_000068: ncbigene

position:623576:1
position: 623576
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:624211:1
position: 624211
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:623576-624211:1:exon

YBR201W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: DER1
locus tag: YBR201W
product: derlin
transcript id: NM_001178549.1
SIO_010081: YBR201W
subclass of: SO_0000673
so part of: YBR201W
location: <623576..>624211
location: region:623576-624211:1
so has part: feature:623576-624211:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:623576-624211:1:exon

YBR201W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: DER1
locus tag: YBR201W
experiment: EXISTENCE:direct assay:GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex [PMID:16873066]
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:8631297]
experiment: EXISTENCE:direct assay:GO:0051787 misfolded protein binding [PMID:24292014]
experiment: EXISTENCE:mutant phenotype:GO:0030433 ubiquitin-dependent ERAD pathway [PMID:23363603|PMID:8631297]
experiment: EXISTENCE:mutant phenotype:GO:0030970 retrograde protein transport, ER to cytosol [PMID:24292014]
experiment: EXISTENCE:mutant phenotype:GO:0070843 misfolded protein transport [PMID:24292014]
experiment: EXISTENCE:physical interaction:GO:0030433 ubiquitin-dependent ERAD pathway [PMID:16619026]
note: ER membrane protein that promotes export of misfolded polypeptides; required for ER-associated protein degradation of misfolded or unassembled proteins; initiates export of aberrant polypeptides from ER lumen by threading them into ER membrane and routing them to Hrd1p for ubiquitination; function normally requires N-terminal acetylation by NatB; N- and C- termini protrude into cytoplasm; similar to Dfm1p; homolog of mammalian derlin-1
codon start: 1
product: derlin
translation: MDAVILNLLGDIPLVTRLWTIGCLVLSGLTSLRIVDPGKVVYSYDLVFKKGQYGRLLYSIFDYGAFNWISMINIFVSANHLSTLENSFNLRRKFCWIIFLLLVILVKMTSIEQPAASLGVLLHENLVYYELKKNGNQMNVRFFGAIDVSPSIFPIYMNAVMYFVYKRSWLEIAMNFMPGHVIYYMDDIIGKIYGIDLCKSPYDWFRNTETP
SIO_010081: YBR201W
subclass of: SO_0000673
so part of: YBR201W
location: 623576..624211
location: region:623576-624211:1
so has part: feature:623576-624211:1:exon

NP_009760.1
type: Protein
SIO_000068: ncbiprotein

S000000405
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:623576-624211:1:exon

YBR201C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MIN7
locus tag: YBR201C-A
so part of: sequence
location: complement(<624493..>624696)
location: region:624493-624696:-1
so has part: feature:624493-624696:-1:exon
subclass of: SO_0000010

3799967
type: Gene
SIO_000068: ncbigene

position:624493:-1
position: 624493
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:624696:-1
position: 624696
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:624493-624696:-1:exon

YBR201C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MIN7
locus tag: YBR201C-A
product: Min7p
transcript id: NM_001184676.3
SIO_010081: YBR201C-A
subclass of: SO_0000673
so part of: YBR201C-A
location: complement(<624493..>624696)
location: region:624493-624696:-1
so has part: feature:624493-624696:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:624493-624696:-1:exon

YBR201C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MIN7
locus tag: YBR201C-A
note: Mitochondrial hypothetical protein
codon start: 1
product: Min7p
translation: MLAMKSFSQVSKSYKASAPSKKLTTLFYVAYITLGLTTPFLLPARMASKDTHYYKDEFCSQRSYTRF
SIO_010081: YBR201C-A
subclass of: SO_0000673
so part of: YBR201C-A
location: complement(624493..624696)
location: region:624493-624696:-1
so has part: feature:624493-624696:-1:exon

NP_001032571.3
type: Protein
SIO_000068: ncbiprotein

S000087085
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:624493-624696:-1:exon

YBR202W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CDC47
gene: MCM7
locus tag: YBR202W
gene synonym: CDC47
so part of: sequence
location: <625772..>628309
location: region:625772-628309:1
so has part: feature:625772-628309:1:exon
subclass of: SO_0000010

852501
type: Gene
SIO_000068: ncbigene

position:625772:1
position: 625772
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:628309:1
position: 628309
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:625772-628309:1:exon

YBR202W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CDC47
gene: MCM7
locus tag: YBR202W
gene synonym: CDC47
product: mini-chromosome maintenance complex protein 7
transcript id: NM_001178550.4
SIO_010081: YBR202W
subclass of: SO_0000673
so part of: YBR202W
location: <625772..>628309
location: region:625772-628309:1
so has part: feature:625772-628309:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:625772-628309:1:exon

YBR202W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CDC47
gene: MCM7
locus tag: YBR202W
gene synonym: CDC47
EC number: 3.6.4.12
experiment: EXISTENCE:direct assay:GO:0003678 DNA helicase activity [PMID:15723534]
experiment: EXISTENCE:direct assay:GO:0003682 chromatin binding [PMID:9159120|PMID:9288745]
experiment: EXISTENCE:direct assay:GO:0003688 DNA replication origin binding [PMID:11756674|PMID:16824194|PMID:9288745]
experiment: EXISTENCE:direct assay:GO:0005524 ATP binding [PMID:12480933]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:10704410|PMID:7708676]
experiment: EXISTENCE:direct assay:GO:0005656 nuclear pre-replicative complex [PMID:16824194|PMID:9335335]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:10704410|PMID:7708676]
experiment: EXISTENCE:direct assay:GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication [PMID:16824194]
experiment: EXISTENCE:direct assay:GO:0006268 DNA unwinding involved in DNA replication [PMID:15723534|PMID:13679365]
experiment: EXISTENCE:direct assay:GO:0009378 four-way junction helicase activity [PMID:13679365]
experiment: EXISTENCE:direct assay:GO:0017116 single-stranded DNA helicase activity [PMID:15723534|PMID:18657510]
experiment: EXISTENCE:direct assay:GO:0031261 DNA replication preinitiation complex [PMID:9554851]
experiment: EXISTENCE:direct assay:GO:0031298 replication fork protection complex [PMID:16531994]
experiment: EXISTENCE:direct assay:GO:0042555 MCM complex [PMID:12480933]
experiment: EXISTENCE:direct assay:GO:0043138 3'-5' DNA helicase activity [PMID:13679365]
experiment: EXISTENCE:direct assay:GO:0071162 CMG complex [PMID:26524492]
experiment: EXISTENCE:direct assay:GO:0097373 MCM core complex [PMID:13679365]
experiment: EXISTENCE:direct assay:GO:1904931 MCM complex binding [PMID:26912723]
experiment: EXISTENCE:genetic interaction:GO:0006270 DNA replication initiation [PMID:10783164|PMID:2044962]
experiment: EXISTENCE:genetic interaction:GO:0006271 DNA strand elongation involved in DNA replication [PMID:10783164]
experiment: EXISTENCE:mutant phenotype:GO:0000727 double-strand break repair via break-induced replication [PMID:20516198]
experiment: EXISTENCE:mutant phenotype:GO:0003697 single-stranded DNA binding [PMID:17895243]
experiment: EXISTENCE:mutant phenotype:GO:0006270 DNA replication initiation [PMID:10783164|PMID:2044962]
experiment: EXISTENCE:mutant phenotype:GO:0006271 DNA strand elongation involved in DNA replication [PMID:10783164|PMID:10834843]
experiment: EXISTENCE:mutant phenotype:GO:0030466 silent mating-type cassette heterochromatin formation [PMID:19064704]
experiment: EXISTENCE:mutant phenotype:GO:0031509 subtelomeric heterochromatin formation [PMID:19064704]
experiment: EXISTENCE:mutant phenotype:GO:0033260 nuclear DNA replication [PMID:2044962]
note: Component of the Mcm2-7 hexameric helicase complex; MCM2-7 primes origins of DNA replication in G1 and becomes an active ATP-dependent helicase that promotes DNA melting and elongation in S-phase; forms an Mcm4p-6p-7p subcomplex
codon start: 1
product: mini-chromosome maintenance complex protein 7
translation: MSAALPSIQLPVDYNNLFNEITDFLVTFKQDTLSSDATRNENEDENLDAENIEQHLLEKGPKYMAMLQKVANRELNSVIIDLDDILQYQNEKFLQGTQADDLVSAIQQNANHFTELFCRAIDNNMPLPTKEIDYKDDVLDVILNQRRLRNERMLSDRTNEIRSENLMDTTMDPPSSMNDALREVVEDETELFPPNLTRRYFLYFKPLSQNCARRYRKKAISSKPLSVRQIKGDFLGQLITVRGIITRVSDVKPAVEVIAYTCDQCGYEVFQEVNSRTFTPLSECTSEECSQNQTKGQLFMSTRASKFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGIFLPAPYTGFKALKAGLLTETYLEAQFVRQHKKKFASFSLTSDVEERVMELITSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYVHMHNKQPDLDFTPVEPSKMREYIAYAKTKRPVMSEAVNDYVVQAYIRLRQDSKREMDSKFSFGQATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVSKESLYQETNKSKEDESPTTKIFTIIKKMLQETGKNTLSYENIVKTVRLRGFTMLQLSNCIQEYSYLNVWHLINEGNTLKFVDDGTMDTDQEDSLVSTPKLAPQTTASANVSAQDSDIDLQDA
SIO_010081: YBR202W
subclass of: SO_0000673
so part of: YBR202W
location: 625772..628309
location: region:625772-628309:1
so has part: feature:625772-628309:1:exon

NP_009761.4
type: Protein
SIO_000068: ncbiprotein

S000000406
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:625772-628309:1:exon

YBR203W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: COS111
locus tag: YBR203W
so part of: sequence
location: <629168..>631942
location: region:629168-631942:1
so has part: feature:629168-631942:1:exon
subclass of: SO_0000010

852502
type: Gene
SIO_000068: ncbigene

position:629168:1
position: 629168
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:631942:1
position: 631942
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:629168-631942:1:exon

YBR203W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: COS111
locus tag: YBR203W
product: Cos111p
transcript id: NM_001178551.2
SIO_010081: YBR203W
subclass of: SO_0000673
so part of: YBR203W
location: <629168..>631942
location: region:629168-631942:1
so has part: feature:629168-631942:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:629168-631942:1:exon

YBR203W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: COS111
locus tag: YBR203W
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961]
experiment: EXISTENCE:mutant phenotype:GO:0007165 signal transduction [PMID:12661761]
note: Protein required for antifungal drug ciclopirox olamine resistance; not related to the subtelomerically-encoded COS family; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
codon start: 1
product: Cos111p
translation: MSSASRLQNVNIVSNNYSRYGTSVYDKLYHSNGSGSNNAGKNSTTVGKLSSISQKSRSKQRHGSNCSRSMSQSPLSTFKSPLSNQNQSSAPDDLASIGQRRSDDVTSLDNETIITMNSRKSRIKKKYKSLISTSSKKFMNKLYDHGASSDSFSIFSLKTSHSGKHENSRFEKLRKRKYHAWGKFADINDLPVEIIAKILSEFELGRDQKTLVRCLYVSKKFYKATKIVLYRLPYFTSTYRVAQFVTSLRLHPDNGAYVKVLDLSHLKPGIIGQDSKDSQGLDDDGHSRRHRRRRRRSTNTSLNLPPATPTSTISNEDDANSGLIKDDASNGSEVEDLALAGWRDWRYRNEPLYSSPLLNSFKLKKVVSRSSSITSTSSGNSTGVHSTRRQRSNSSVASITTSIMSSIYNTSHVSLSSTTSNTSNGNISSGSNLSRVSTAGSLKKASAKSTRSSPQKAKPISDITSSSWFRMRLSSRNRKARTANTINLKNSKDKSDDDFKVLKHDSGHPSNYRSSTLKFSIEQPFSTHHPYANKFLLKYAPYKDLPLGYILHMLNLCPNLVELNLSNLVICTDFKLINQRSERRRMTSSLLPAVQESSVSAGPEKDLEIVYMTDSGKGYEYYEGLSKKHSRSSSLGTNPSSWIGGQANWTDYPPPIDAQTKTREEHRRNNTLNNKNVVLKKLNPFEIFEMICNRNEEKGGYCSLTKVKMNDIVWCRQYMVKYFVMRTFRQHLDYKSMENNSYERHLFSFRDSGLDRNFSWACNAKLHEFVALMVMDHLSNLDDLGLEELFNIKSEKLYIKNYCCRDPDILEISNLFDIRYGAGSEADATSDSNLEAESLQFRLTILKTEKPTSFWLTKVSKDYVSLVVKLCVDDDIDMDKMKVGKPTLRIDSITHNLISRLKELRRVDLRRNVGENNYYAESII
SIO_010081: YBR203W
subclass of: SO_0000673
so part of: YBR203W
location: 629168..631942
location: region:629168-631942:1
so has part: feature:629168-631942:1:exon

NP_009762.2
type: Protein
SIO_000068: ncbiprotein

S000000407
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:629168-631942:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS221; Autonomously Replicating Sequence
so part of: sequence
location: 631939..632251
location: region:631939-632251:1
so has part: feature:631939-632251:1:region

S000130153
type: SGD
SIO_000068: sgd

position:631939:1
position: 631939
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:632251:1
position: 632251
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:631939-632251:1:region

YBR204C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: LDH1
locus tag: YBR204C
so part of: sequence
location: complement(<632254..>633381)
location: region:632254-633381:-1
so has part: feature:632254-633381:-1:exon
subclass of: SO_0000010

852503
type: Gene
SIO_000068: ncbigene

position:632254:-1
position: 632254
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:633381:-1
position: 633381
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:632254-633381:-1:exon

YBR204C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: LDH1
locus tag: YBR204C
product: triacylglycerol lipase
transcript id: NM_001178552.2
SIO_010081: YBR204C
subclass of: SO_0000673
so part of: YBR204C
location: complement(<632254..>633381)
location: region:632254-633381:-1
so has part: feature:632254-633381:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:632254-633381:-1:exon

YBR204C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: LDH1
locus tag: YBR204C
EC number: 3.1.1.3
experiment: EXISTENCE:direct assay:GO:0004806 triglyceride lipase activity [PMID:21478434]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005811 lipid droplet [PMID:21478430|PMID:24868093]
experiment: EXISTENCE:direct assay:GO:0016788 hydrolase activity, acting on ester bonds [PMID:21478434]
experiment: EXISTENCE:direct assay:GO:0017171 serine hydrolase activity [PMID:14645503]
experiment: EXISTENCE:mutant phenotype:GO:0055088 lipid homeostasis [PMID:21478434]
note: Serine hydrolase; exhibits active esterase plus weak triacylglycerol lipase activities; proposed role in lipid homeostasis, regulating phospholipid and non-polar lipid levels and required for mobilization of LD-stored lipids; localizes to the lipid droplet (LD) surface; contains a classical serine containing catalytic triad (GxSxG motif)
codon start: 1
product: triacylglycerol lipase
translation: MNMAERAEATKSWSCEPLSGKTLEEIVQNAENAADLVAYIRKPEVDLDFRLKFIAEHEEFFNVQLSDRNSRIRTCHNLSDKGIRGDTVFVFVPGLAGNLEQFEPLLELVDSDQKAFLTLDLPGFGHSSEWSDYPMLKVVELIFVLVCDVLRKWSTAVPNNDNVNPFNGHKIVLVGHSMGCFLACHLYEQHMADTKAVQTLVLLTPPKAHIEQLSKDKHIIQWALYGVFKLPWLFDVYRNKFDQVKGLQSSGIKQYFYQQGDDVKLKYRKFWQFKNNISNKSRTIIGYLLGWETVDWVKFNGVLTQTDMKQKIIIFGAEKDPIAPIENLEFYKQTINKECLRKVIILPDCSHNLCFDRPELVCENFQREVIDNSKL
SIO_010081: YBR204C
subclass of: SO_0000673
so part of: YBR204C
location: complement(632254..633381)
location: region:632254-633381:-1
so has part: feature:632254-633381:-1:exon

NP_009763.2
type: Protein
SIO_000068: ncbiprotein

S000000408
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:632254-633381:-1:exon

YBR205W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: KTR3
locus tag: YBR205W
so part of: sequence
location: <633622..>634836
location: region:633622-634836:1
so has part: feature:633622-634836:1:exon
subclass of: SO_0000010

852504
type: Gene
SIO_000068: ncbigene

position:633622:1
position: 633622
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:634836:1
position: 634836
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:633622-634836:1:exon

YBR205W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: KTR3
locus tag: YBR205W
product: mannosyltransferase KTR3
transcript id: NM_001178553.3
SIO_010081: YBR205W
subclass of: SO_0000673
so part of: YBR205W
location: <633622..>634836
location: region:633622-634836:1
so has part: feature:633622-634836:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:633622-634836:1:exon

YBR205W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: KTR3
locus tag: YBR205W
experiment: EXISTENCE:direct assay:GO:0000324 fungal-type vacuole [PMID:14562095|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22842922]
experiment: EXISTENCE:genetic interaction:GO:0006491 N-glycan processing [PMID:9182588]
experiment: EXISTENCE:genetic interaction:GO:0006493 protein O-linked glycosylation [PMID:9182588]
experiment: EXISTENCE:mutant phenotype:GO:0000030 mannosyltransferase activity [PMID:9182588]
note: Putative alpha-1,2-mannosyltransferase; involved in O- and N-linked protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family; Svp26p mediates uptake of Ktr3p into COPII vesicles; relocalizes from nucleus to vacuole upon DNA replication stress
codon start: 1
product: mannosyltransferase KTR3
translation: MSVHHKKKLMPKSALLIRKYQKGIRSSFIGLIIVLSFLFFMSGSRSPEVPIAQGTSVSRVASKDYLMPFTDKSQGVIHPVDDGKKEKGVMVTLARNSDLWNLVKSIRHVEDRFNNRYHYDWVFLNDQPFSDEFKRVTSALVSGKAKYGTIPKDHWSIPSWIDTEKFDEKRLAMGKLDIPYGSSVPYRHMCRFQSGFIWRHPLLEEYEWFWRVDTDITLFCDIQYDIFKFLKVNNKKYGFILSVSEYERTIPTLWETTKKFIKKNPKFLHKNNLMKFISNDDGDTYNMCHFWTNFEIGSLDFFRSDAYREYFDYLDSSGGFFYERWGDAPVHSIAASLFLDKSEIHFFDGLGFHHPDFTSCPIEQKIRLQNKCICEPSKDVTWTPDYFCTRKYFSAGNYKLPPGI
SIO_010081: YBR205W
subclass of: SO_0000673
so part of: YBR205W
location: 633622..634836
location: region:633622-634836:1
so has part: feature:633622-634836:1:exon

NP_009764.3
type: Protein
SIO_000068: ncbiprotein

S000000409
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:633622-634836:1:exon

YBR207W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FTH1
locus tag: YBR207W
so part of: sequence
location: <635146..>636543
location: region:635146-636543:1
so has part: feature:635146-636543:1:exon
subclass of: SO_0000010

852506
type: Gene
SIO_000068: ncbigene

position:635146:1
position: 635146
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:636543:1
position: 636543
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:635146-636543:1:exon

YBR207W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FTH1
locus tag: YBR207W
product: Fth1p
transcript id: NM_001178555.4
SIO_010081: YBR207W
subclass of: SO_0000673
so part of: YBR207W
location: <635146..>636543
location: region:635146-636543:1
so has part: feature:635146-636543:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:635146-636543:1:exon

YBR207W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FTH1
locus tag: YBR207W
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:10608875|PMID:23836928|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0045121 membrane raft [PMID:23836928]
experiment: EXISTENCE:genetic interaction:GO:0034755 iron ion transmembrane transport [PMID:10608875]
experiment: EXISTENCE:mutant phenotype:GO:0006897 endocytosis [PMID:11378903]
note: Putative high affinity iron transporter; involved in transport of intravacuolar stores of iron; forms complex with Fet5p; expression is regulated by iron; proposed to play indirect role in endocytosis; protein abundance increases in response to DNA replication stress
codon start: 1
product: Fth1p
translation: MAFEDYFSFQIFFIFLRESLEIVVIVSILLTIVKQGLSVEDDSPFEGSSSSAGLPSPNTNTNADSTTAFLQAGPSDGNAIGTSATAANNKSRPLNVEEEEEIYEYSNELRDQDRESDEHTADNVKLYQKLKIQILAGGAFGLLLCMLIGGAFVSIFYHIGTDLWTLSEHYYEGVLSLVASVIISVMGLFFLRMGKLREKFRVKLASIIYSKDNNLLGNKTQKGVKFSEKYSFFILPFITTLREGLEAVVFIGGIGIDQPLSSIPLSMVLATAISTVFGIFFFRYSSSLSLKICLVVATCFLYLIAAGLFSKGVWQLELQDYVNKCNGQDMSEVGNGPGSYDISRSVWHVNCCNGEKDGGWMIFTAIFGWTNSATVGSVISYNAYWLVLICALKLLMIEEKYGYIPYLPISWQKKRIMKRLSIAKASLDLKHHTSELNSSTSEPDSQRRSKDSSVPLIIDSSGSAN
SIO_010081: YBR207W
subclass of: SO_0000673
so part of: YBR207W
location: 635146..636543
location: region:635146-636543:1
so has part: feature:635146-636543:1:exon

NP_009766.4
type: Protein
SIO_000068: ncbiprotein

S000000411
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:635146-636543:1:exon

YBR208C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: DUR80
gene: DUR12
locus tag: YBR208C
gene synonym: DUR80
so part of: sequence
location: complement(<636703..>642210)
location: region:636703-642210:-1
so has part: feature:636703-642210:-1:exon
subclass of: SO_0000010

852507
type: Gene
SIO_000068: ncbigene

position:636703:-1
position: 636703
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:642210:-1
position: 642210
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:636703-642210:-1:exon

YBR208C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: DUR80
gene: DUR12
locus tag: YBR208C
gene synonym: DUR80
product: bifunctional urea carboxylase/allophanate hydrolase
transcript id: NM_001178556.1
SIO_010081: YBR208C
subclass of: SO_0000673
so part of: YBR208C
location: complement(<636703..>642210)
location: region:636703-642210:-1
so has part: feature:636703-642210:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:636703-642210:-1:exon

YBR208C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: DUR80
gene: DUR12
locus tag: YBR208C
gene synonym: DUR80
EC number: 3.5.1.54
EC number: 6.3.4.6
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095|PMID:22842922]
experiment: EXISTENCE:mutant phenotype:GO:0004039 allophanate hydrolase activity [PMID:6105114]
experiment: EXISTENCE:mutant phenotype:GO:0004847 urea carboxylase activity [PMID:6105114]
experiment: EXISTENCE:mutant phenotype:GO:0043419 urea catabolic process [PMID:6105114]
note: Urea amidolyase; contains both urea carboxylase and allophanate hydrolase activities, degrades urea to CO2 and NH3; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation; protein abundance increases in response to DNA replication stress
codon start: 1
product: bifunctional urea carboxylase/allophanate hydrolase
translation: MTVSSDTTAEISLGWSIQDWIDFHKSSSSQASLRLLESLLDSQNVAPVDNAWISLISKENLLHQFQILKSRENKETLPLYGVPIAVKDNIDVRGLPTTAACPSFAYEPSKDSKVVELLRNAGAIIVGKTNLDQFATGLVGTRSPYGKTPCAFSKEHVSGGSSAGSASVVARGIVPIALGTDTAGSGRVPAALNNLIGLKPTKGVFSCQGVVPACKSLDCVSIFALNLSDAERCFRIMCQPDPDNDEYSRPYVSNPLKKFSSNVTIAIPKNIPWYGETKNPVLFSNAVENLSRTGANVIEIDFEPLLELARCLYEGTWVAERYQAIQSFLDSKPPKESLDPTVISIIEGAKKYSAVDCFSFEYKRQGILQKVRRLLESVDVLCVPTCPLNPTMQQVADEPVLVNSRQGTWTNFVNLADLAALAVPAGFRDDGLPNGITLIGKKFTDYALLELANRYFQNIFPNGSRTYGTFTSSSVKPANDQLVGPDYDPSTSIKLAVVGAHLKGLPLHWQLEKVNATYLCTTKTSKAYQLFALPKNGPVLKPGLRRVQDSNGSQIELEVYSVPKELFGAFISMVPEPLGIGSVELESGEWIKSFICEESGYKAKGTVDITKYGGFRAYFEMLKKKESQKKKLFDTVLIANRGEIAVRIIKTLKKLGIRSVAVYSDPDKYSQHVTDADVSVPLHGTTAAQTYLDMNKIIDAAKQTNAQAIIPGYGFLSENADFSDACTSAGITFVGPSGDIIRGLGLKHSARQIAQKAGVPLVPGSLLITSVEEAKKVAAELEYPVMVKSTAGGGGIGLQKVDSEEDIEHIFETVKHQGETFFGDAGVFLERFIENARHVEVQLMGDGFGKAIALGERDCSLQRRNQKVIEETPAPNLPEKTRLALRKAAESLGSLLNYKCAGTVEFIYDEKKDEFYFLEVNTRLQVEHPITEMVTGLDLVEWMIRIAANDAPDFDSTKVEVNGVSMEARLYAENPLKNFRPSPGLLVDVKFPDWARVDTWVKKGTNISPEYDPTLAKIIVHGKDRDDAISKLNQALEETKVYGCITNIDYLKSIITSDFFAKAKVSTNILNSYQYEPTAIEITLPGAHTSIQDYPGRVGYWRIGVPPSGPMDAYSFRLANRIVGNDYRTPAIEVTLTGPSIVFHCETVIAITGGTALCTLDGQEIPQHKPVEVKRGSTLSIGKLTSGCRAYLGIRGGIDVPKYLGSYSTFTLGNVGGYNGRVLKLGDVLFLPSNEENKSVECLPQNIPQSLIPQISETKEWRIGVTCGPHGSPDFFKPESIEEFFSEKWKVHYNSNRFGVRLIGPKPKWARSNGGEGGMHPSNTHDYVYSLGAINFTGDEPVIITCDGPSLGGFVCQAVVPEAELWKVGQVKPGDSIQFVPLSYESSRSLKESQDVAIKSLDGTKLRRLDSVSILPSFETPILAQMEKVNELSPKVVYRQAGDRYVLVEYGDNEMNFNISYRIECLISLVKKNKTIGIVEMSQGVRSVLIEFDGYKVTQKELLKVLVAYETEIQFDENWKITSNIIRLPMAFEDSKTLACVQRYQETIRSSAPWLPNNVDFIANVNGISRNEVYDMLYSARFMVLGLGDVFLGSPCAVPLDPRHRFLGSKYNPSRTYTERGAVGIGGMYMCIYAANSPGGYQLVGRTIPIWDKLCLAASSEVPWLMNPFDQVEFYPVSEEDLDKMTEDCDNGVYKVNIEKSVFDHQEYLRWINANKDSITAFQEGQLGERAEEFAKLIQNANSELKESVTVKPDEEEDFPEGAEIVYSEYSGRFWKSIASVGDVIEAGQGLLIIEAMKAEMIISAPKSGKIIKICHGNGDMVDSGDIVAVIETLA
SIO_010081: YBR208C
subclass of: SO_0000673
so part of: YBR208C
location: complement(636703..642210)
location: region:636703-642210:-1
so has part: feature:636703-642210:-1:exon

NP_009767.1
type: Protein
SIO_000068: ncbiprotein

S000000412
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:636703-642210:-1:exon

YBR209W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YBR209W
so part of: sequence
location: <642583..>642900
location: region:642583-642900:1
so has part: feature:642583-642900:1:exon
subclass of: SO_0000010

852508
type: Gene
SIO_000068: ncbigene

position:642583:1
position: 642583
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:642900:1
position: 642900
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:642583-642900:1:exon

YBR209W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YBR209W
product: uncharacterized protein
transcript id: NM_001348891.1
SIO_010081: YBR209W
subclass of: SO_0000673
so part of: YBR209W
location: <642583..>642900
location: region:642583-642900:1
so has part: feature:642583-642900:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:642583-642900:1:exon

YBR209W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YBR209W
note: hypothetical protein; conserved across S. cerevisiae strains; YBR209W is not an essential gene
codon start: 1
product: uncharacterized protein
translation: MNAYWFHYRASIKKEAPNYKRTFLGRARNAFLLILSEAYLLFVFLSYLIRGKSLEKRVNDEAKCSQRCVPLQLANNLAFGDRHKRSANFKKGIANTHSSLICSKP
SIO_010081: YBR209W
subclass of: SO_0000673
so part of: YBR209W
location: 642583..642900
location: region:642583-642900:1
so has part: feature:642583-642900:1:exon

NP_001335746.1
type: Protein
SIO_000068: ncbiprotein

S000000413
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:642583-642900:1:exon

YNCB0017C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCB0017C
so part of: sequence
location: complement(643007..643078)
location: region:643007-643078:-1
so has part: feature:643007-643078:-1:exon
subclass of: SO_0000663

852509
type: Gene
SIO_000068: ncbigene

position:643007:-1
position: 643007
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:643078:-1
position: 643078
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:643007-643078:-1:exon

YNCB0017C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCB0017C
product: tRNA-Cys
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Cysteine tRNA (tRNA-Cys), predicted by tRNAscan-SE analysis
SIO_010081: YNCB0017C
subclass of: SO_0000673
so part of: YNCB0017C
location: complement(643007..643078)
location: region:643007-643078:-1
so has part: feature:643007-643078:-1:exon

S000006526
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:643007-643078:-1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty4 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(643488..643858)
location: region:643488-643858:-1
so has part: feature:643488-643858:-1:region

S000006820
type: SGD
SIO_000068: sgd

position:643488:-1
position: 643488
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:643858:-1
position: 643858
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:643488-643858:-1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 643859..644002
location: region:643859-644002:1
so has part: feature:643859-644002:1:region

S000006812
type: SGD
SIO_000068: sgd

position:643859:1
position: 643859
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:644002:1
position: 644002
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:643859-644002:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(644362..644603)
location: region:644362-644603:-1
so has part: feature:644362-644603:-1:region

S000006813
type: SGD
SIO_000068: sgd

position:644362:-1
position: 644362
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:644603:-1
position: 644603
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:644362-644603:-1:region

YNCB0018W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCB0018W
so part of: sequence
location: 645167..645238
location: region:645167-645238:1
so has part: feature:645167-645238:1:exon
subclass of: SO_0000663

852510
type: Gene
SIO_000068: ncbigene

position:645167:1
position: 645167
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:645238:1
position: 645238
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:645167-645238:1:exon

YNCB0018W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCB0018W
product: tRNA-Glu
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Glutamate tRNA (tRNA-Glu), predicted by tRNAscan-SE analysis; thiolation of uridine at wobble position (34) requires Ncs6p
SIO_010081: YNCB0018W
subclass of: SO_0000673
so part of: YNCB0018W
location: 645167..645238
location: region:645167-645238:1
so has part: feature:645167-645238:1:exon

S000006548
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:645167-645238:1:exon

YBR210W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ERV15
locus tag: YBR210W
so part of: sequence
location: <645550..>645978
location: region:645550-645978:1
so has part: feature:645550-645978:1:exon
subclass of: SO_0000010

852511
type: Gene
SIO_000068: ncbigene

position:645550:1
position: 645550
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:645978:1
position: 645978
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:645550-645978:1:exon

YBR210W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ERV15
locus tag: YBR210W
product: Erv15p
transcript id: NM_001178558.1
SIO_010081: YBR210W
subclass of: SO_0000673
so part of: YBR210W
location: <645550..>645978
location: region:645550-645978:1
so has part: feature:645550-645978:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:645550-645978:1:exon

YBR210W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ERV15
locus tag: YBR210W
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport [PMID:17298976]
experiment: EXISTENCE:genetic interaction:GO:0030134 COPII-coated ER to Golgi transport vesicle [PMID:17298976]
note: Protein involved in export of proteins from the endoplasmic reticulum; ERV15 has a paralog, ERV14, that arose from the whole genome duplication
codon start: 1
product: Erv15p
translation: MSGTGLSLFVTGLILNCLNSICQIYFTILYGDLEADYINSIELCKRVNRLSVPEAILQAFISALFLFNGYWFVFLLNVPVLAYNASKVYKKTHLLDATDIFRKLGRCKIECFLKLGFYLLIFFFYFYRMVTALLENDANLIS
SIO_010081: YBR210W
subclass of: SO_0000673
so part of: YBR210W
location: 645550..645978
location: region:645550-645978:1
so has part: feature:645550-645978:1:exon

NP_009769.1
type: Protein
SIO_000068: ncbiprotein

S000000414
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:645550-645978:1:exon

YBR211C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: ARP100
gene: AME1
locus tag: YBR211C
gene synonym: ARP100
so part of: sequence
location: complement(<646158..>647132)
location: region:646158-647132:-1
so has part: feature:646158-647132:-1:exon
subclass of: SO_0000010

852512
type: Gene
SIO_000068: ncbigene

position:646158:-1
position: 646158
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:647132:-1
position: 647132
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:646158-647132:-1:exon

YBR211C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: ARP100
gene: AME1
locus tag: YBR211C
gene synonym: ARP100
product: Ame1p
transcript id: NM_001178559.3
SIO_010081: YBR211C
subclass of: SO_0000673
so part of: YBR211C
location: complement(<646158..>647132)
location: region:646158-647132:-1
so has part: feature:646158-647132:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:646158-647132:-1:exon

YBR211C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: ARP100
gene: AME1
locus tag: YBR211C
gene synonym: ARP100
experiment: EXISTENCE:direct assay:GO:0000776 kinetochore [PMID:14633972]
experiment: EXISTENCE:direct assay:GO:0000817 COMA complex [PMID:14633972]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005816 spindle pole body [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0008608 attachment of spindle microtubules to kinetochore [PMID:14633972]
experiment: EXISTENCE:mutant phenotype:GO:0034501 protein localization to kinetochore [PMID:19597337]
experiment: EXISTENCE:physical interaction:GO:0008608 attachment of spindle microtubules to kinetochore [PMID:14633972]
note: Essential kinetochore protein associated with microtubules and SPBs; component of the kinetochore sub-complex COMA (Ctf19p, Okp1p, Mcm21p, Ame1p); involved in spindle checkpoint maintenance; orthologous to human centromere constitutive-associated network (CCAN) subunit CENP-U and fission yeast Mis17; relative distribution to the nucleus increases upon DNA replication stress
codon start: 1
product: Ame1p
translation: MDRDTKLAFRLRGSHSRRTDDIDDDVIVFKTPNAVYREENSPIQSPVQPILSSPKLANSFEFPITTNNVNAQDRHEHGYQPLDAEDYPMIDSENKSLISESPQNVRNDEDLTTRYNFDDIPIRQLSSSITSVTTIDVLSSLFINLFENDLIPQALKDFNKSDDDQFRKLLYKLDLRLFQTISDQMTRDLKDILDINVSNNELCYQLKQVLARKEDLNQQIISVRNEIQELKAGKDWHDLQNEQAKLNDKVKLNKRLNDLTSTLLGKYEGDRKIMSQDSEDDSIRDDSNILDIAHFVDLMDPYNGLLKKINKINENLSNELQPSL
SIO_010081: YBR211C
subclass of: SO_0000673
so part of: YBR211C
location: complement(646158..647132)
location: region:646158-647132:-1
so has part: feature:646158-647132:-1:exon

NP_009770.3
type: Protein
SIO_000068: ncbiprotein

S000000415
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:646158-647132:-1:exon

YBR212W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: RBP1
gene: NGR1
locus tag: YBR212W
gene synonym: RBP1
so part of: sequence
location: <647886..>649904
location: region:647886-649904:1
so has part: feature:647886-649904:1:exon
subclass of: SO_0000010

852513
type: Gene
SIO_000068: ncbigene

position:647886:1
position: 647886
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:649904:1
position: 649904
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:647886-649904:1:exon

YBR212W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: RBP1
gene: NGR1
locus tag: YBR212W
gene synonym: RBP1
product: Ngr1p
transcript id: NM_001178560.3
SIO_010081: YBR212W
subclass of: SO_0000673
so part of: YBR212W
location: <647886..>649904
location: region:647886-649904:1
so has part: feature:647886-649904:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:647886-649904:1:exon

YBR212W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: RBP1
gene: NGR1
locus tag: YBR212W
gene synonym: RBP1
experiment: EXISTENCE:direct assay:GO:0000932 P-body [PMID:16885161]
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:14570877|PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0010494 cytoplasmic stress granule [PMID:18981231|PMID:19470581|PMID:26777405]
experiment: EXISTENCE:direct assay:GO:0048471 perinuclear region of cytoplasm [PMID:14570877]
experiment: EXISTENCE:direct assay:GO:0061158 3'-UTR-mediated mRNA destabilization [PMID:14570877]
experiment: EXISTENCE:mutant phenotype:GO:0007005 mitochondrion organization [PMID:14570877]
experiment: EXISTENCE:mutant phenotype:GO:0061158 3'-UTR-mediated mRNA destabilization [PMID:14570877]
note: RNA binding protein that negatively regulates growth rate; interacts with the 3' UTR of the mitochondrial porin (POR1) mRNA and enhances its degradation; overexpression impairs mitochondrial function; interacts with Dhh1p to mediate POR1 mRNA decay; expressed in stationary phase
codon start: 1
product: Ngr1p
translation: MMSNVANASQRQENPYIIPLPPSSTVETSTEPPRTLWMGDLDPSFDEATIEEIWSKLDKKVIVKLIRAKKNLLIPCSSTSSSNNNTSEENAENQQSASNSTDQLDNSQMININGISFIDPSTTQLHHAGYCFVEFETQKDAKFALSLNATPLPNFYSPTTNSQTNPTFKRTFRLNWASGATLQSSIPSTPEFSLFVGDLSPTATEADLLSLFQTRFKSVKTVRVMTDPLTGSSRCFGFVRFGDEDERRRALIEMSGKWFQGRALRVAYATPRNNMMLQLQEQQQQQQQLQQQHQQLDQEDNNGPLLIKTANNLIQNNSNMLPLNALHNAPPMHLNEGGISNMRVNDSLPSNTYNTDPTNTTVFVGGLVPKTTEFQLRSLFKPFGPILNVRIPNGKNCGFVKFEKRIDAEASIQGLQGFIVGGSPIRLSWGRPSSSNAKTNSTIMGASQYMSSNGLRAPSAASSVDNSKQILEQYAEDKRRLFLHQQQQQQQQQQQDGNFSMEQMAHNNYYNYNNYDYHRNKNGSHSDLVNLQRSNVPYMQEDGALYPHQYSSPSYSLHPTGNQFSNATNNLPQFGNAMSISMQLPNGNSNKTASSMNTNPNTNMIMNSNMNMNMNVNPVPYGMGNGANMYDVSRMMTPPLNIAPNSNNSKSSIMNKHPNRNNVPPIHPSLLH
SIO_010081: YBR212W
subclass of: SO_0000673
so part of: YBR212W
location: 647886..649904
location: region:647886-649904:1
so has part: feature:647886-649904:1:exon

NP_009771.3
type: Protein
SIO_000068: ncbiprotein

S000000416
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:647886-649904:1:exon

YBR213W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MET8
locus tag: YBR213W
so part of: sequence
location: <650368..>651192
location: region:650368-651192:1
so has part: feature:650368-651192:1:exon
subclass of: SO_0000010

852514
type: Gene
SIO_000068: ncbigene

position:650368:1
position: 650368
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:651192:1
position: 651192
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:650368-651192:1:exon

YBR213W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MET8
locus tag: YBR213W
product: bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase MET8
transcript id: NM_001178561.1
SIO_010081: YBR213W
subclass of: SO_0000673
so part of: YBR213W
location: <650368..>651192
location: region:650368-651192:1
so has part: feature:650368-651192:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:650368-651192:1:exon

YBR213W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MET8
locus tag: YBR213W
EC number: 1.3.1.76
EC number: 4.99.1.4
experiment: EXISTENCE:direct assay:GO:0004325 ferrochelatase activity [PMID:11980703]
experiment: EXISTENCE:direct assay:GO:0043115 precorrin-2 dehydrogenase activity [PMID:10051442|PMID:11980703]
experiment: EXISTENCE:mutant phenotype:GO:0000103 sulfate assimilation [PMID:10051442]
experiment: EXISTENCE:mutant phenotype:GO:0019354 siroheme biosynthetic process [PMID:9003798]
note: Bifunctional dehydrogenase and ferrochelatase; involved in the biosynthesis of siroheme, a prosthetic group used by sulfite reductase; required for sulfate assimilation and methionine biosynthesis
codon start: 1
product: bifunctional precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase MET8
translation: MVKSLQLAHQLKDKKILLIGGGEVGLTRLYKLIPTGCKLTLVSPDLHKSIIPKFGKFIQNEDQPDYREDAKRFINPNWDPTKNEIYEYIRSDFKDEYLDLEDENDAWYIIMTCIPDHPESARIYHLCKERFGKQQLVNVADKPDLCDFYFGANLEIGDRLQILISTNGLSPRFGALVRDEIRNLFTQMGDLALEDAVVKLGELRRGIRLLAPDDKDVKYRMDWARRCTDLFGIQHCHNIDVKRLLDLFKVMFQEQNCSLQFPPRERLLSEYCSS
SIO_010081: YBR213W
subclass of: SO_0000673
so part of: YBR213W
location: 650368..651192
location: region:650368-651192:1
so has part: feature:650368-651192:1:exon

NP_009772.1
type: Protein
SIO_000068: ncbiprotein

S000000417
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:650368-651192:1:exon

YBR214W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SDS24
locus tag: YBR214W
so part of: sequence
location: <651415..>652998
location: region:651415-652998:1
so has part: feature:651415-652998:1:exon
subclass of: SO_0000010

852515
type: Gene
SIO_000068: ncbigene

position:651415:1
position: 651415
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:652998:1
position: 652998
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:651415-652998:1:exon

YBR214W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SDS24
locus tag: YBR214W
product: Sds24p
transcript id: NM_001178562.1
SIO_010081: YBR214W
subclass of: SO_0000673
so part of: YBR214W
location: <651415..>652998
location: region:651415-652998:1
so has part: feature:651415-652998:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:651415-652998:1:exon

YBR214W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SDS24
locus tag: YBR214W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095|PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:genetic interaction:GO:0000920 septum digestion after cytokinesis [PMID:16041152]
experiment: EXISTENCE:mutant phenotype:GO:0006897 endocytosis [PMID:11378903]
note: Protein involved in cell separation during budding; one of two S. cerevisiae homologs (Sds23p and Sds24p) of the S. pombe Sds23 protein, which is implicated in APC/cyclosome regulation; may play an indirect role in fluid-phase endocytosis; protein abundance increases in response to DNA replication stress; SDS24 has a paralog, SDS23, that arose from the whole genome duplication
codon start: 1
product: Sds24p
translation: MASTSNTFPPSQSNSSNNLPTSRHASIVEMLSTPPLLPHVQVNDTDDKEQPEESTPPTATAAAPGPGCAATPAPLRDEKPQFKLSAVPMTQTPSQCLSCVHAQKWQHIPLSQLIEQNKLIFVPGSISVEEAFNTLIKYHLNSIPVESFPGDMNCFTFDYNDLNSYLLLVLNKITVSNKQLTADCQNGKPVPVGEMVKLTPKNPFYKLPENESLSTVMGILGSGVHRVAITNEEMTKVKGILSQRRLIKYLWDNARSFTSLEPLLNSSLQDLHIGVLNIQSKPTSRQSRVISIQGEEPLIMGLYKMHVERISSIAVIDKQGNLLGNISVTDVKHVTRTSQYPLLHKTCRHFISVILNSRGLETGKDSFPIFHVYPSSSLARTLAKLVATKSHRLWIVQPPESSTSASSTNLTAANTAANAVSATAQSSANGATPMSKSSSSTSLNSHSPLMTAMEDPPSPRSSAIAIPPPSPASSTNTPNLFEKEYRTGKLIGVVSLTDIINLLARKQTGNKEVDPQSARRQRGSIAM
SIO_010081: YBR214W
subclass of: SO_0000673
so part of: YBR214W
location: 651415..652998
location: region:651415-652998:1
so has part: feature:651415-652998:1:exon

NP_009773.1
type: Protein
SIO_000068: ncbiprotein

S000000418
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:651415-652998:1:exon

YBR215W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HPC2
locus tag: YBR215W
so part of: sequence
location: <653356..>655317
location: region:653356-655317:1
so has part: feature:653356-655317:1:exon
subclass of: SO_0000010

852516
type: Gene
SIO_000068: ncbigene