Saccharomyces cerevisiae S288C chromosome I, complete sequence.
type: Entry
definition: Saccharomyces cerevisiae S288C chromosome I, complete sequence.
sequence version: NC_001133.9
sequence date: 2023-01-18
sequence: sequence
division: CON
label: NC_001133.9
type: RefSeq
SIO_000068: refseq
dblink: PRJNA128
keyword: RefSeq
source: Saccharomyces cerevisiae S288C
organism: Saccharomyces cerevisiae S288C
taxonomy: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
reference: 1
references: 34897464
reference: 2
references: 8849441
reference: 3
references: 7731988
reference: 4
reference: 5
reference: 6
comment: REVIEWED REFSEQ: This record has been curated by SGD. The reference\nsequence is identical to BK006935.\n\nOn Apr 26, 2011 this sequence version replaced NC_001133.8.\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: SGD\nAnnotation Status :: Full Annotation\nAnnotation Version :: R64-3-1\nURL :: http://www.yeastgenome.org/\n##Genome-Annotation-Data-END##\nCOMPLETENESS: full length.

sequence
subclass of: SO_0000340
sequence length: 230218
topology: linear
so has quality: SO_0000987
location: 1..230218
location: region:1-230218:1
RO_0002162: 559292

NC_001133
type: RefSeq
SIO_000068: refseq

PRJNA128
type: BioProject
SIO_000068: bioproject

1
title: New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources
author: Engel, S.R.
author: Wong, E.D.
author: Nash, R.S.
author: Aleksander, S.
author: Alexander, M.
author: Douglass, E.
author: Karra, K.
author: Miyasato, S.R.
author: Simison, M.
author: Skrzypek, M.S.
author: Weng, S.
author: Cherry, J.M.
journal: Genetics 220 (4) (2022)
pubmed: 34897464

34897464
type: PubMed
SIO_000068: pubmed

2
title: Life with 6000 genes
author: Goffeau, A.
author: Barrell, B.G.
author: Bussey, H.
author: Davis, R.W.
author: Dujon, B.
author: Feldmann, H.
author: Galibert, F.
author: Hoheisel, J.D.
author: Jacq, C.
author: Johnston, M.
author: Louis, E.J.
author: Mewes, H.W.
author: Murakami, Y.
author: Philippsen, P.
author: Tettelin, H.
author: Oliver, S.G.
journal: Science 274 (5287), 546 (1996)
pubmed: 8849441

8849441
type: PubMed
SIO_000068: pubmed

3
title: The nucleotide sequence of chromosome I from Saccharomyces cerevisiae
author: Bussey, H.
author: Kaback, D.B.
author: Zhong, W.
author: Vo, D.T.
author: Clark, M.W.
author: Fortin, N.
author: Hall, J.
author: Ouellette, B.F.
author: Keng, T.
author: Barton, A.B. et al.
journal: Proc. Natl. Acad. Sci. U.S.A.
volume: 92
issue: 9
pages: 3809-3813
year: 1995
pubmed: 7731988

7731988
type: PubMed
SIO_000068: pubmed

4
title: Direct Submission
journal: Submitted (13-JAN-2023) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA

5
title: Direct Submission
journal: Submitted (31-MAR-2011) Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA
comments: Sequence update by submitter

6
title: Direct Submission
journal: Submitted (11-DEC-2009) Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA

position:1:1
position: 1
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:230218:1
position: 230218
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

feature:1-230218:1:source
so part of: sequence
organism: Saccharomyces cerevisiae S288C
mol type: genomic DNA
strain: S288C
chromosome: I

559292
type: Taxonomy
SIO_000068: taxonomy

telomere
type: Telomere
subclass of: SO_0000624
RO_0002162: 559292
note: TEL01L; Telomeric region on the left arm of Chromosome I; composed of an X element core sequence, X element combinatorial repeats, and a short terminal stretch of telomeric repeats
so part of: sequence
location: complement(1..801)
location: region:1-801:-1
so has part: feature:1-801:-1:region

S000028862
type: SGD
SIO_000068: sgd

position:1:-1
position: 1
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:801:-1
position: 801
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:1-801:-1:region

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS102; Autonomously Replicating Sequence
so part of: sequence
location: 707..776
location: region:707-776:1
so has part: feature:707-776:1:region

S000121252
type: SGD
SIO_000068: sgd

position:707:1
position: 707
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:776:1
position: 776
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:707-776:1:region

YAL068C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PAU8
locus tag: YAL068C
so part of: sequence
location: complement(<1807..>2169)
location: region:1807-2169:-1
so has part: feature:1807-2169:-1:exon
subclass of: SO_0000010

851229
type: Gene
SIO_000068: ncbigene

position:1807:-1
position: 1807
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:2169:-1
position: 2169
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:1807-2169:-1:exon

YAL068C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PAU8
locus tag: YAL068C
product: seripauperin PAU8
transcript id: NM_001180043.1
SIO_010081: YAL068C
subclass of: SO_0000673
so part of: YAL068C
location: complement(<1807..>2169)
location: region:1807-2169:-1
so has part: feature:1807-2169:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:1807-2169:-1:exon

YAL068C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PAU8
locus tag: YAL068C
experiment: EXISTENCE:mutant phenotype:GO:0030437 ascospore formation [PMID:12586695]
note: hypothetical protein; member of the seripauperin multigene family encoded mainly in subtelomeric regions
codon start: 1
product: seripauperin PAU8
translation: MVKLTSIAAGVAAIAATASATTTLAQSDERVNLVELGVYVSDIRAHLAQYYMFQAAHPTETYPVEVAEAVFNYGDFTTMLTGIAPDQVTRMITGVPWYSSRLKPAISSALSKDGIYTIAN
SIO_010081: YAL068C
subclass of: SO_0000673
so part of: YAL068C
location: complement(1807..2169)
location: region:1807-2169:-1
so has part: feature:1807-2169:-1:exon

NP_009332.1
type: Protein
SIO_000068: ncbiprotein

S000002142
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:1807-2169:-1:exon

YAL067W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YAL067W-A
so part of: sequence
location: <2480..>2707
location: region:2480-2707:1
so has part: feature:2480-2707:1:exon
subclass of: SO_0000010

1466426
type: Gene
SIO_000068: ncbigene

position:2480:1
position: 2480
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:2707:1
position: 2707
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:2480-2707:1:exon

YAL067W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YAL067W-A
product: uncharacterized protein
transcript id: NM_001184582.1
SIO_010081: YAL067W-A
subclass of: SO_0000673
so part of: YAL067W-A
location: <2480..>2707
location: region:2480-2707:1
so has part: feature:2480-2707:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:2480-2707:1:exon

YAL067W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YAL067W-A
note: hypothetical protein; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
codon start: 1
product: uncharacterized protein
translation: MPIIGVPRCLIKPFSVPVTFPFSVKKNIRILDLDPRTEAYCLSLNSVCFKRLPRRKYFHLLNSYNIKRVLGVVYC
SIO_010081: YAL067W-A
subclass of: SO_0000673
so part of: YAL067W-A
location: 2480..2707
location: region:2480-2707:1
so has part: feature:2480-2707:1:exon

NP_878038.1
type: Protein
SIO_000068: ncbiprotein

S000028593
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:2480-2707:1:exon

YAL067C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SEO1
locus tag: YAL067C
so part of: sequence
location: complement(<7235..>9016)
location: region:7235-9016:-1
so has part: feature:7235-9016:-1:exon
subclass of: SO_0000010

851230
type: Gene
SIO_000068: ncbigene

position:7235:-1
position: 7235
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:9016:-1
position: 9016
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:7235-9016:-1:exon

YAL067C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SEO1
locus tag: YAL067C
product: putative permease SEO1
transcript id: NM_001178208.1
SIO_010081: YAL067C
subclass of: SO_0000673
so part of: YAL067C
location: complement(<7235..>9016)
location: region:7235-9016:-1
so has part: feature:7235-9016:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:7235-9016:-1:exon

YAL067C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SEO1
locus tag: YAL067C
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0055085 transmembrane transport [PMID:8893857]
note: Putative permease; member of the allantoate transporter subfamily of the major facilitator superfamily; mutation confers resistance to ethionine sulfoxide
codon start: 1
product: putative permease SEO1
translation: MYSIVKEIIVDPYKRLKWGFIPVKRQVEDLPDDLNSTEIVTISNSIQSHETAENFITTTSEKDQLHFETSSYSEHKDNVNVTRSYEYRDEADRPWWRFFDEQEYRINEKERSHNKWYSWFKQGTSFKEKKLLIKLDVLLAFYSCIAYWVKYLDTVNINNAYVSGMKEDLGFQGNDLVHTQVMYTVGNIIFQLPFLIYLNKLPLNYVLPSLDLCWSLLTVGAAYVNSVPHLKAIRFFIGAFEAPSYLAYQYLFGSFYKHDEMVRRSAFYYLGQYIGILSAGGIQSAVYSSLNGVNGLEGWRWNFIIDAIVSVVVGLIGFYSLPGDPYNCYSIFLTDDEIRLARKRLKENQTGKSDFETKVFDIKLWKTIFSDWKIYILTLWNIFCWNDSNVSSGAYLLWLKSLKRYSIPKLNQLSMITPGLGMVYLMLTGIIADKLHSRWFAIIFTQVFNIIGNSILAAWDVAEGAKWFAFMLQCFGWAMAPVLYSWQNDICRRDAQTRAITLVTMNIMAQSSTAWISVLVWKTEEAPRYLKGFTFTACSAFCLSIWTFVVLYFYKRDERNNAKKNGIVLYNSKHGVEKPTSKDVETLSVSDEK
SIO_010081: YAL067C
subclass of: SO_0000673
so part of: YAL067C
location: complement(7235..9016)
location: region:7235-9016:-1
so has part: feature:7235-9016:-1:exon

NP_009333.1
type: Protein
SIO_000068: ncbiprotein

S000000062
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:7235-9016:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS103; Autonomously Replicating Sequence; replication origin of very weak function
so part of: sequence
location: 7997..8547
location: region:7997-8547:1
so has part: feature:7997-8547:1:region

S000121253
type: SGD
SIO_000068: sgd

position:7997:1
position: 7997
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:8547:1
position: 8547
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:7997-8547:1:region

YAL065C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YAL065C
so part of: sequence
location: complement(<11565..>11951)
location: region:11565-11951:-1
so has part: feature:11565-11951:-1:exon
subclass of: SO_0000010

851232
type: Gene
SIO_000068: ncbigene

position:11565:-1
position: 11565
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:11951:-1
position: 11951
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:11565-11951:-1:exon

YAL065C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YAL065C
product: uncharacterized protein
transcript id: NM_001179897.1
SIO_010081: YAL065C
subclass of: SO_0000673
so part of: YAL065C
location: complement(<11565..>11951)
location: region:11565-11951:-1
so has part: feature:11565-11951:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:11565-11951:-1:exon

YAL065C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YAL065C
note: hypothetical protein; shows sequence similarity to FLO1 and other flocculins
codon start: 1
product: uncharacterized protein
translation: MNSATSETTTNTGAAETTTSTGAAETKTVVTSSISRFNHAETQTASATDVIGHSSSVVSVSETGNTKSLITSGLSTMSQQPRSTPASSIIGSSTASLEISTYVGIANGLLTNNGISVFISTVLLAIVW
SIO_010081: YAL065C
subclass of: SO_0000673
so part of: YAL065C
location: complement(11565..11951)
location: region:11565-11951:-1
so has part: feature:11565-11951:-1:exon

NP_009335.1
type: Protein
SIO_000068: ncbiprotein

S000001817
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:11565-11951:-1:exon

YAL064W-B
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YAL064W-B
so part of: sequence
location: <12046..>12426
location: region:12046-12426:1
so has part: feature:12046-12426:1:exon
subclass of: SO_0000010

851233
type: Gene
SIO_000068: ncbigene

position:12046:1
position: 12046
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:12426:1
position: 12426
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:12046-12426:1:exon

YAL064W-B
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YAL064W-B
product: uncharacterized protein
transcript id: NM_001180042.1
SIO_010081: YAL064W-B
subclass of: SO_0000673
so part of: YAL064W-B
location: <12046..>12426
location: region:12046-12426:1
so has part: feature:12046-12426:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:12046-12426:1:exon

YAL064W-B
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YAL064W-B
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
note: Fungal-specific hypothetical protein
codon start: 1
product: uncharacterized protein
translation: MAGEAVSEHTPDSQEVTVTSVVCCLDSVVEIGHHVVYSVVTPLIVAVLIDTMAGEAVLEHTSDSQEEIVTTVVCSVVPLVCFVVSVVCFVISVVEIGHHVVYSVVAPLTVTVAVETIAEEMDSVHT
SIO_010081: YAL064W-B
subclass of: SO_0000673
so part of: YAL064W-B
location: 12046..12426
location: region:12046-12426:1
so has part: feature:12046-12426:1:exon

NP_009336.1
type: Protein
SIO_000068: ncbiprotein

S000002141
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:12046-12426:1:exon

YAL064C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YAL065C-A
gene: TDA8
locus tag: YAL064C-A
gene synonym: YAL065C-A
so part of: sequence
location: complement(<13363..>13743)
location: region:13363-13743:-1
so has part: feature:13363-13743:-1:exon
subclass of: SO_0000010

851234
type: Gene
SIO_000068: ncbigene

position:13363:-1
position: 13363
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:13743:-1
position: 13743
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:13363-13743:-1:exon

YAL064C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YAL065C-A
gene: TDA8
locus tag: YAL064C-A
gene synonym: YAL065C-A
product: Tda8p
transcript id: NM_001180041.1
SIO_010081: YAL064C-A
subclass of: SO_0000673
so part of: YAL064C-A
location: complement(<13363..>13743)
location: region:13363-13743:-1
so has part: feature:13363-13743:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:13363-13743:-1:exon

YAL064C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YAL065C-A
gene: TDA8
locus tag: YAL064C-A
gene synonym: YAL065C-A
note: hypothetical protein; null mutant is sensitive to expression of the top1-T722A allele; not an essential gene
codon start: 1
product: Tda8p
translation: MTGYFLPPQTSSYTFRFAKVDDSAILSVGGDVAFGCCAQEQPPITSTNFTINGIKPWQGRLPDNIAGTVYMYAGFYCPMKIVYSNAVSWHTLPVSVELPDVTTVSDDFAGHVYSFDDDLTAQLYYP
SIO_010081: YAL064C-A
subclass of: SO_0000673
so part of: YAL064C-A
location: complement(13363..13743)
location: region:13363-13743:-1
so has part: feature:13363-13743:-1:exon

NP_058136.1
type: Protein
SIO_000068: ncbiprotein

S000002140
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:13363-13743:-1:exon

YAL064W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YAL064W
so part of: sequence
location: <21566..>21850
location: region:21566-21850:1
so has part: feature:21566-21850:1:exon
subclass of: SO_0000010

851235
type: Gene
SIO_000068: ncbigene

position:21566:1
position: 21566
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:21850:1
position: 21850
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:21566-21850:1:exon

YAL064W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YAL064W
product: uncharacterized protein
transcript id: NM_001178206.2
SIO_010081: YAL064W
subclass of: SO_0000673
so part of: YAL064W
location: <21566..>21850
location: region:21566-21850:1
so has part: feature:21566-21850:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:21566-21850:1:exon

YAL064W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YAL064W
note: hypothetical protein; may interact with ribosomes, based on co-purification experiments
codon start: 1
product: uncharacterized protein
translation: MNPFASLEGQDNISSVFFLHMQQFESQVKDRFRFPIFRLERKTFGNSCYQVETLKVKCRPRHAKSCNLLTLLFKSRTQSVLVPNFGFLILNSEP
SIO_010081: YAL064W
subclass of: SO_0000673
so part of: YAL064W
location: 21566..21850
location: region:21566-21850:1
so has part: feature:21566-21850:1:exon

NP_009337.2
type: Protein
SIO_000068: ncbiprotein

S000000060
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:21566-21850:1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 22230..22552
location: region:22230-22552:1
so has part: feature:22230-22552:1:region

S000006787
type: SGD
SIO_000068: sgd

position:22230:1
position: 22230
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:22552:1
position: 22552
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:22230-22552:1:region

YAL063C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YAL063C-A
so part of: sequence
location: complement(<22395..>22685)
location: region:22395-22685:-1
so has part: feature:22395-22685:-1:exon
subclass of: SO_0000010

1466427
type: Gene
SIO_000068: ncbigene

position:22395:-1
position: 22395
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:22685:-1
position: 22685
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:22395-22685:-1:exon

YAL063C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YAL063C-A
product: uncharacterized protein
transcript id: NM_001184642.1
SIO_010081: YAL063C-A
subclass of: SO_0000673
so part of: YAL063C-A
location: complement(<22395..>22685)
location: region:22395-22685:-1
so has part: feature:22395-22685:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:22395-22685:-1:exon

YAL063C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YAL063C-A
note: hypothetical protein; identified by expression profiling and mass spectrometry
codon start: 1
product: uncharacterized protein
translation: MCPRTVLLIININHWFYDKNIVRIILTFRLDSGHISDICFINKNLANALITADISLLKRHDIRCTKYIITYYQRYRNKEKGKFISLCKNTIISSSV
SIO_010081: YAL063C-A
subclass of: SO_0000673
so part of: YAL063C-A
location: complement(22395..22685)
location: region:22395-22685:-1
so has part: feature:22395-22685:-1:exon

NP_878039.1
type: Protein
SIO_000068: ncbiprotein

S000028813
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:22395-22685:-1:exon

YAL063C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FLO9
locus tag: YAL063C
so part of: sequence
location: complement(<24000..>27968)
location: region:24000-27968:-1
so has part: feature:24000-27968:-1:exon
subclass of: SO_0000010

851236
type: Gene
SIO_000068: ncbigene

position:24000:-1
position: 24000
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:27968:-1
position: 27968
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:24000-27968:-1:exon

YAL063C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FLO9
locus tag: YAL063C
product: flocculin FLO9
transcript id: NM_001178205.1
SIO_010081: YAL063C
subclass of: SO_0000673
so part of: YAL063C
location: complement(<24000..>27968)
location: region:24000-27968:-1
so has part: feature:24000-27968:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:24000-27968:-1:exon

YAL063C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FLO9
locus tag: YAL063C
experiment: EXISTENCE:mutant phenotype:GO:0000128 flocculation [PMID:19420680|PMID:19087208]
experiment: EXISTENCE:mutant phenotype:GO:0031589 cell-substrate adhesion [PMID:19087208]
note: Lectin-like protein with similarity to Flo1p; thought to be expressed and involved in flocculation
codon start: 1
product: flocculin FLO9
translation: MSLAHYCLLLAIVTLLGLTNVVSATTAACLPANSRKNGMNVNFYQYSLRDSSTYSNAAYMAYGYASKTKLGSVGGQTDISIDYNIPCVSSSGTFPCPQEDLYGNWGCKGIGACSNNPIIAYWSTDLFGFYTTPTNVTLEMTGYFLPPQTGSYTFKFATVDDSAILSVGGSIAFECCAQEQPPITSTNFTINGIKPWNGSPPDNITGTVYMYAGFYYPMKIVYSNAVAWGTLPISVTLPDGTTVSDDFEGYVYTFDNNLSQPNCTIPDPSNYTVSTTITTTEPWTGTFTSTSTEMTTVTGTNGVPTDETVIVIRTPTTASTIITTTEPWNSTFTSTSTELTTVTGTNGVRTDETIIVIRTPTTATTAITTTEPWNSTFTSTSTELTTVTGTNGLPTDETIIVIRTPTTATTAMTTTQPWNDTFTSTSTELTTVTGTNGLPTDETIIVIRTPTTATTAMTTTQPWNDTFTSTSTELTTVTGTNGLPTDETIIVIRTPTTATTAMTTTQPWNDTFTSTSTEITTVTGTNGLPTDETIIVIRTPTTATTAMTTTQPWNDTFTSTSTEMTTVTGTNGLPTDETIIVIRTPTTATTAITTTEPWNSTFTSTSTEMTTVTGTNGLPTDETIIVIRTPTTATTAITTTQPWNDTFTSTSTEMTTVTGTNGLPTDETIIVIRTPTTATTAMTTTQPWNDTFTSTSTEITTVTGTNGLPTDETIIVIRTPTTATTAMTTTQPWNDTFTSTSTEMTTVTGTNGVPTDETVIVIRTPTSEGLISTTTEPWTGTFTSTSTEMTTVTGTNGQPTDETVIVIRTPTSEGLVTTTTEPWTGTFTSTSTEMTTITGTNGQPTDETVIIVKTPTTAISSSLSSSSGQITSFITSARPIITPFYPSNGTSVISSSVISSSDTSSLVISSSVTSSLVTSSPVISSSFISSPVISSTTTSASILSESSKSSVIPTSSSTSGSSESETGSASSASSSSSISSESPKSTYSSSSLPPVTSATTSQEITSSLPPVTTTKTSEQTTLVTVTSCESHVCTESISSAIVSTATVTVSGATTEYTTWCPISTTEITKQTTETTKQTKGTTEQTTETTKQTTVVTISSCESDVCSKTASPAIVSTSTATINGVTTEYTTWCPISTTESKQQTTLVTVTSCGSGVCSETTSPAIVSTATATVNDVVTVYSTWRPQTTNEQSVSSKMNSATSETTTNTGAAETTTSTGAAETKTVVTSSISRFNHAETQTASATDVIGHSSSVVSVSETGNTKSLTSSGLSTMSQQPRSTPASSMVGSSTASLEISTYAGSANSLLAGSGLSVFIASLLLAII
SIO_010081: YAL063C
subclass of: SO_0000673
so part of: YAL063C
location: complement(24000..27968)
location: region:24000-27968:-1
so has part: feature:24000-27968:-1:exon

NP_009338.1
type: Protein
SIO_000068: ncbiprotein

S000000059
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:24000-27968:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS104; Autonomously Replicating Sequence
so part of: sequence
location: 30946..31183
location: region:30946-31183:1
so has part: feature:30946-31183:1:region

S000118317
type: SGD
SIO_000068: sgd

position:30946:1
position: 30946
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:31183:1
position: 31183
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:30946-31183:1:region

YAL062W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: FUN51
gene: GDH3
locus tag: YAL062W
gene synonym: FUN51
so part of: sequence
location: <31567..>32940
location: region:31567-32940:1
so has part: feature:31567-32940:1:exon
subclass of: SO_0000010

851237
type: Gene
SIO_000068: ncbigene

position:31567:1
position: 31567
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:32940:1
position: 32940
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:31567-32940:1:exon

YAL062W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: FUN51
gene: GDH3
locus tag: YAL062W
gene synonym: FUN51
product: glutamate dehydrogenase (NADP(+)) GDH3
transcript id: NM_001178204.1
SIO_010081: YAL062W
subclass of: SO_0000673
so part of: YAL062W
location: <31567..>32940
location: region:31567-32940:1
so has part: feature:31567-32940:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:31567-32940:1:exon

YAL062W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: FUN51
gene: GDH3
locus tag: YAL062W
gene synonym: FUN51
EC number: 1.4.1.4
experiment: EXISTENCE:direct assay:GO:0004354 glutamate dehydrogenase (NADP+) activity [PMID:11562373]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:4126]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:mutant phenotype:GO:0004354 glutamate dehydrogenase (NADP+) activity [PMID:9287019]
experiment: EXISTENCE:mutant phenotype:GO:0006537 glutamate biosynthetic process [PMID:9287019]
note: NADP(+)-dependent glutamate dehydrogenase; synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh1p; expression regulated by nitrogen and carbon sources; GDH3 has a paralog, GDH1, that arose from the whole genome duplication
codon start: 1
product: glutamate dehydrogenase (NADP(+)) GDH3
translation: MTSEPEFQQAYDEIVSSVEDSKIFEKFPQYKKVLPIVSVPERIIQFRVTWENDNGEQEVAQGYRVQFNSAKGPYKGGLRFHPSVNLSILKFLGFEQIFKNALTGLDMGGGKGGLCVDLKGKSDNEIRRICYAFMRELSRHIGKDTDVPAGDIGVGGREIGYLFGAYRSYKNSWEGVLTGKGLNWGGSLIRPEATGFGLVYYTQAMIDYATNGKESFEGKRVTISGSGNVAQYAALKVIELGGIVVSLSDSKGCIISETGITSEQIHDIASAKIRFKSLEEIVDEYSTFSESKMKYVAGARPWTHVSNVDIALPCATQNEVSGDEAKALVASGVKFVAEGANMGSTPEAISVFETARSTATNAKDAVWFGPPKAANLGGVAVSGLEMAQNSQKVTWTAERVDQELKKIMINCFNDCIQAAQEYSTEKNTNTLPSLVKGANIASFVMVADAMLDQGDVF
SIO_010081: YAL062W
subclass of: SO_0000673
so part of: YAL062W
location: 31567..32940
location: region:31567-32940:1
so has part: feature:31567-32940:1:exon

NP_009339.1
type: Protein
SIO_000068: ncbiprotein

S000000058
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:31567-32940:1:exon

YAL061W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: BDH2
locus tag: YAL061W
so part of: sequence
location: <33448..>34701
location: region:33448-34701:1
so has part: feature:33448-34701:1:exon
subclass of: SO_0000010

851238
type: Gene
SIO_000068: ncbigene

position:33448:1
position: 33448
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:34701:1
position: 34701
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:33448-34701:1:exon

YAL061W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: BDH2
locus tag: YAL061W
product: putative dehydrogenase BDH2
transcript id: NM_001178203.1
SIO_010081: YAL061W
subclass of: SO_0000673
so part of: YAL061W
location: <33448..>34701
location: region:33448-34701:1
so has part: feature:33448-34701:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:33448-34701:1:exon

YAL061W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: BDH2
locus tag: YAL061W
EC number: 1.1.1.303
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
note: Putative medium-chain alcohol dehydrogenase with similarity to BDH1; transcription induced by constitutively active PDR1 and PDR3
codon start: 1
product: putative dehydrogenase BDH2
translation: MRALAYFGKGNIRFTNHLKEPHIVAPDELVIDIEWCGICGTDLHEYTDGPIFFPEDGHTHEISHNPLPQAMGHEMAGTVLEVGPGVKNLKVGDKVVVEPTGTCRDRYRWPLSPNVDKEWCAACKKGYYNICSYLGLCGAGVQSGGFAERVVMNESHCYKVPDFVPLDVAALIQPLAVCWHAIRVCEFKAGSTALIIGAGPIGLGTILALNAAGCKDIVVSEPAKVRRELAEKMGARVYDPTAHAAKESIDYLRSIADGGDGFDYTFDCSGLEVTLNAAIQCLTFRGTAVNLAMWGHHKIQFSPMDITLHERKYTGSMCYTHHDFEAVIEALEEGRIDIDRARHMITGRVNIEDGLDGAIMKLINEKESTIKIILTPNNHGELNREADNEKKEISELSSRKDQERLRESINEAKLRHT
SIO_010081: YAL061W
subclass of: SO_0000673
so part of: YAL061W
location: 33448..34701
location: region:33448-34701:1
so has part: feature:33448-34701:1:exon

NP_009340.1
type: Protein
SIO_000068: ncbiprotein

S000000057
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:33448-34701:1:exon

YAL060W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: BDH1
locus tag: YAL060W
so part of: sequence
location: <35155..>36303
location: region:35155-36303:1
so has part: feature:35155-36303:1:exon
subclass of: SO_0000010

851239
type: Gene
SIO_000068: ncbigene

position:35155:1
position: 35155
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:36303:1
position: 36303
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:35155-36303:1:exon

YAL060W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: BDH1
locus tag: YAL060W
product: (R,R)-butanediol dehydrogenase
transcript id: NM_001178202.2
SIO_010081: YAL060W
subclass of: SO_0000673
so part of: YAL060W
location: <35155..>36303
location: region:35155-36303:1
so has part: feature:35155-36303:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:35155-36303:1:exon

YAL060W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: BDH1
locus tag: YAL060W
EC number: 1.1.1.4
experiment: EXISTENCE:direct assay:GO:0000721 (R,R)-butanediol dehydrogenase activity [PMID:10938079]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11914276|PMID:14562095]
experiment: EXISTENCE:mutant phenotype:GO:0006066 alcohol metabolic process [PMID:10938079]
experiment: EXISTENCE:mutant phenotype:GO:0034079 butanediol biosynthetic process [PMID:19966022]
note: NAD-dependent (R,R)-butanediol dehydrogenase; catalyzes oxidation of (R,R)-2,3-butanediol to (3R)-acetoin, oxidation of meso-butanediol to (3S)-acetoin, and reduction of acetoin; enhances use of 2,3-butanediol as an aerobic carbon source
codon start: 1
product: (R,R)-butanediol dehydrogenase
translation: MRALAYFKKGDIHFTNDIPRPEIQTDDEVIIDVSWCGICGSDLHEYLDGPIFMPKDGECHKLSNAALPLAMGHEMSGIVSKVGPKVTKVKVGDHVVVDAASSCADLHCWPHSKFYNSKPCDACQRGSENLCTHAGFVGLGVISGGFAEQVVVSQHHIIPVPKEIPLDVAALVEPLSVTWHAVKISGFKKGSSALVLGAGPIGLCTILVLKGMGASKIVVSEIAERRIEMAKKLGVEVFNPSKHGHKSIEILRGLTKSHDGFDYSYDCSGIQVTFETSLKALTFKGTATNIAVWGPKPVPFQPMDVTLQEKVMTGSIGYVVEDFEEVVRAIHNGDIAMEDCKQLITGKQRIEDGWEKGFQELMDHKESNVKILLTPNNHGEMK
SIO_010081: YAL060W
subclass of: SO_0000673
so part of: YAL060W
location: 35155..36303
location: region:35155-36303:1
so has part: feature:35155-36303:1:exon

NP_009341.2
type: Protein
SIO_000068: ncbiprotein

S000000056
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:35155-36303:1:exon

YAL059W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ECM1
locus tag: YAL059W
so part of: sequence
location: <36509..>37147
location: region:36509-37147:1
so has part: feature:36509-37147:1:exon
subclass of: SO_0000010

851240
type: Gene
SIO_000068: ncbigene

position:36509:1
position: 36509
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:37147:1
position: 37147
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:36509-37147:1:exon

YAL059W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ECM1
locus tag: YAL059W
product: Ecm1p
transcript id: NM_001178201.2
SIO_010081: YAL059W
subclass of: SO_0000673
so part of: YAL059W
location: <36509..>37147
location: region:36509-37147:1
so has part: feature:36509-37147:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:36509-37147:1:exon

YAL059W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ECM1
locus tag: YAL059W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:11583615|PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:11583615]
experiment: EXISTENCE:direct assay:GO:0030687 preribosome, large subunit precursor [PMID:20348449]
experiment: EXISTENCE:genetic interaction:GO:0000055 ribosomal large subunit export from nucleus [PMID:11583615|PMID:20348449]
note: Pre-ribosomal factor involved in 60S ribosomal protein subunit export; associates with the pre-60S particle; shuttles between the nucleus and cytoplasm
codon start: 1
product: Ecm1p
translation: MWEQRRQKVVFSLTILVRYRLKQSMAKKISKNSRAARQSDALEPEVKDLSELPRAEKTDLTNILIRTAAKNEALLEAKISKKANKSKRGKKLNKKALEDKLANSISSMDRDRLVKALNFTNRLDGKIAKSISRAKYIQNTRKAGWDSTNETIKKELAFLNGGLSVQAKSASEGNAEKEDEEIPEVFDSLAEDNTVQKTPTNRFGVLPDDVEE
SIO_010081: YAL059W
subclass of: SO_0000673
so part of: YAL059W
location: 36509..37147
location: region:36509-37147:1
so has part: feature:36509-37147:1:exon

NP_009342.2
type: Protein
SIO_000068: ncbiprotein

S000000055
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:36509-37147:1:exon

YAL058W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: FUN48
gene: CNE1
locus tag: YAL058W
gene synonym: FUN48
so part of: sequence
location: <37464..>38972
location: region:37464-38972:1
so has part: feature:37464-38972:1:exon
subclass of: SO_0000010

851241
type: Gene
SIO_000068: ncbigene

position:37464:1
position: 37464
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:38972:1
position: 38972
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:37464-38972:1:exon

YAL058W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: FUN48
gene: CNE1
locus tag: YAL058W
gene synonym: FUN48
product: calnexin
transcript id: NM_001178200.1
SIO_010081: YAL058W
subclass of: SO_0000673
so part of: YAL058W
location: <37464..>38972
location: region:37464-38972:1
so has part: feature:37464-38972:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:37464-38972:1:exon

YAL058W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: FUN48
gene: CNE1
locus tag: YAL058W
gene synonym: FUN48
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:7814381]
experiment: EXISTENCE:direct assay:GO:0051082 unfolded protein binding [PMID:16002399]
experiment: EXISTENCE:mutant phenotype:GO:0006457 protein folding [PMID:15173200]
experiment: EXISTENCE:mutant phenotype:GO:0030433 ubiquitin-dependent ERAD pathway [PMID:7814381]
experiment: EXISTENCE:mutant phenotype:GO:0051082 unfolded protein binding [PMID:15173200]
experiment: EXISTENCE:physical interaction:GO:0005515 protein binding [PMID:16002399]
note: Calnexin; integral membrane ER chaperone involved in folding and quality control of glycoproteins; chaperone activity is inhibited by Mpd1p, with which Cne1p interacts; 24% identical to mammalian calnexin; Ca+ binding not yet shown in yeast
codon start: 1
product: calnexin
translation: MKFSAYLWWLFLNLALVKGTSLLSNVTLAEDSFWEHFQAYTNTKHLNQEWITSEAVNNEGSKIYGAQWRLSQGRLQGSAWDKGIAVRTGNAAAMIGHLLETPINVSETDTLVVQYEIKLDNSLTCGGAFIKLMSGFMNVEALKHYAPDTEGVELVFGPDYCAPEINGVQFAINKVDKITHESKLRYLQEMPLSKLTDTSQSHLYTLIIDESAQSFQILIDGKTVMVREHIEDKKKVNFEPPITPPLMIPDVSVAKPHDWDDRIRIPDPEAVKLSDRDERDPLMIPHPDGTEPPEWNSSIPEYILDPNAQKPSWWKELEHGEWIPPMIKNPLCTAERGCGQQIPGLINNAKYKGPGELNEIINPNYMGEWHPPEIENPLYYEEQHPLRIENVISGVILEFWSGSPNMLISNIYVGKNVTEAQIIGNKTWLMRDRAFRGSDGPTERKFMNSRLGNLQTTFHNERESPNPFDRIIDRILEQPLKFVLTAAVVLLTTSVLCCVVFT
SIO_010081: YAL058W
subclass of: SO_0000673
so part of: YAL058W
location: 37464..38972
location: region:37464-38972:1
so has part: feature:37464-38972:1:exon

NP_009343.1
type: Protein
SIO_000068: ncbiprotein

S000000054
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:37464-38972:1:exon

YAL056W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: KRH1
gene: GPB2
locus tag: YAL056W
gene synonym: KRH1
so part of: sequence
location: <39259..>41901
location: region:39259-41901:1
so has part: feature:39259-41901:1:exon
subclass of: SO_0000010

851243
type: Gene
SIO_000068: ncbigene

position:39259:1
position: 39259
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:41901:1
position: 41901
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:39259-41901:1:exon

YAL056W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: KRH1
gene: GPB2
locus tag: YAL056W
gene synonym: KRH1
product: Gpb2p
transcript id: NM_001178199.2
SIO_010081: YAL056W
subclass of: SO_0000673
so part of: YAL056W
location: <39259..>41901
location: region:39259-41901:1
so has part: feature:39259-41901:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:39259-41901:1:exon

YAL056W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: KRH1
gene: GPB2
locus tag: YAL056W
gene synonym: KRH1
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:16030250]
experiment: EXISTENCE:genetic interaction:GO:0001403 invasive growth in response to glucose limitation [PMID:12150916]
experiment: EXISTENCE:genetic interaction:GO:0004862 cAMP-dependent protein kinase inhibitor activity [PMID:16278446|PMID:16924114]
experiment: EXISTENCE:genetic interaction:GO:0007124 pseudohyphal growth [PMID:12150916]
experiment: EXISTENCE:genetic interaction:GO:0010255 glucose mediated signaling pathway [PMID:12150916]
experiment: EXISTENCE:genetic interaction:GO:0046580 negative regulation of Ras protein signal transduction [PMID:16793550]
experiment: EXISTENCE:mutant phenotype:GO:0001403 invasive growth in response to glucose limitation [PMID:12150916]
experiment: EXISTENCE:mutant phenotype:GO:0007124 pseudohyphal growth [PMID:12150916]
experiment: EXISTENCE:mutant phenotype:GO:0010255 glucose mediated signaling pathway [PMID:12150916]
experiment: EXISTENCE:mutant phenotype:GO:0030437 ascospore formation [PMID:12586695]
experiment: EXISTENCE:physical interaction:GO:0032794 GTPase activating protein binding [PMID:16793550]
note: Multistep regulator of cAMP-PKA signaling; inhibits PKA downstream of Gpa2p and Cyr1p, thereby increasing cAMP dependency; inhibits Ras activity through direct interactions with Ira1p/2p; regulated by G-alpha protein Gpa2p; GPB2 has a paralog, GPB1, that arose from the whole genome duplication
codon start: 1
product: Gpb2p
translation: MEISSSPWNDGGYSPYERNRVAVSPFSSALEGEERIETSRSLGDHCFEPLPYVTNYLSIFALFGKEIFGDKGNVSSRNEYLLKKYYSLKKPFVLRHNGHALKNPDMPLQRNDILQTNFMVDKFLNRTVRSVNFNNFKIISDMQSKSGRGTKSGTNQNQSADAIQNICLPSIPSALPYFQYYRKLLTVNTKEWDILKLHSLWVPKLRKDFKDFSLYGDKNSLKPIDSHYDEDNTMKKNLFFERSPSRQTLDGKGCASKGYDISSGNMIIPSLFSEDKLPALTYHCSVELNGNIYIFGGLMPCYSYEEDAPMLNDFFVDGIKNLPPPLLPQVINNPSMVNNPHLYVASIPSCRFSKPKMGGYIPPPLLCVQGSKLTDRHIFFYGGFEIRTETRGDENGKYHLKKRLYVNNTGYILDIMSFKFTKIDIIVQPSKYNAYPTMSSRFGHLQISIDNPNRRASVHSSSMNEIHKMGSASMKQGSSITSGRLEKAAVLSSLPHNTVHTVIIFGGYRQTGDDRYEAMNDLWKIEIPVIRRGKKGYCKFSETANAILLTPSEKDKSDWPEERAFSAFSVHGTSLMDRSSLDMRLLNNLKNHFVLKPSYISQDRVVSPKPVFPMMVHGTHQDLFNSGSAAQESPKAGASASSASAASFDPDMDDNLENYIVNPGRKSSSIPMTAIGRQRLILSQEKPVGKTVVLHGGSNGLNVLDDMWLMDLECETWTPIETFAKADSSEDGDEKLDSVNVGLVGHRMESIGRICVCIGGMVQEDVDQFYSENDDEPPRKRKVDTLPLGGNFLNTIDLSTQCWEEHKITLSKKEDDEDRQDSENEDTNSNIVVGVGGTSLQCDKSIILIGGLISRRSNVKEIYLHGTITKSIFPSVNPSA
SIO_010081: YAL056W
subclass of: SO_0000673
so part of: YAL056W
location: 39259..41901
location: region:39259-41901:1
so has part: feature:39259-41901:1:exon

NP_009345.3
type: Protein
SIO_000068: ncbiprotein

S000000052
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:39259-41901:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS105; Autonomously Replicating Sequence
so part of: sequence
location: 41992..42151
location: region:41992-42151:1
so has part: feature:41992-42151:1:region

S000121254
type: SGD
SIO_000068: sgd

position:41992:1
position: 41992
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:42151:1
position: 42151
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:41992-42151:1:region

YAL055W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YAF5
gene: PEX22
locus tag: YAL055W
gene synonym: YAF5
so part of: sequence
location: <42177..>42719
location: region:42177-42719:1
so has part: feature:42177-42719:1:exon
subclass of: SO_0000010

851244
type: Gene
SIO_000068: ncbigene

position:42177:1
position: 42177
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:42719:1
position: 42719
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:42177-42719:1:exon

YAL055W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YAF5
gene: PEX22
locus tag: YAL055W
gene synonym: YAF5
product: ubiquitin-protein transferase activating protein PEX22
transcript id: NM_001178198.1
SIO_010081: YAL055W
subclass of: SO_0000673
so part of: YAL055W
location: <42177..>42719
location: region:42177-42719:1
so has part: feature:42177-42719:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:42177-42719:1:exon

YAL055W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YAF5
gene: PEX22
locus tag: YAL055W
gene synonym: YAF5
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:24390141]
experiment: EXISTENCE:direct assay:GO:0031398 positive regulation of protein ubiquitination [PMID:25162638]
experiment: EXISTENCE:direct assay:GO:0097027 ubiquitin-protein transferase activator activity [PMID:22085930]
experiment: EXISTENCE:direct assay:GO:1902499 positive regulation of protein autoubiquitination [PMID:25162638]
experiment: EXISTENCE:mutant phenotype:GO:0016562 protein import into peroxisome matrix, receptor recycling [PMID:17452527]
note: Putative peroxisomal membrane protein; required for import of peroxisomal proteins; functionally complements a Pichia pastoris pex22 mutation
codon start: 1
product: ubiquitin-protein transferase activating protein PEX22
translation: MPPPSRSRINKTRTLGIVGTAIAVLVTSYYIYQKVTSAKEDNGARPPEGDSVKENKKARKSKCIIMSKSIQGLPIKWEEYAADEVVLLVPTSHTDGSMKQAIGDAFRKTKNEHKIIYCDSMDGLWSCVRRLGKFQCILNSRDFTSSGGSDAAVVPEDIGRFVKFVVDSDVEDVLIDTLCN
SIO_010081: YAL055W
subclass of: SO_0000673
so part of: YAL055W
location: 42177..42719
location: region:42177-42719:1
so has part: feature:42177-42719:1:exon

NP_009346.1
type: Protein
SIO_000068: ncbiprotein

S000000051
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:42177-42719:1:exon

YAL054C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: FUN44
gene: ACS1
locus tag: YAL054C
gene synonym: FUN44
so part of: sequence
location: complement(<42881..>45022)
location: region:42881-45022:-1
so has part: feature:42881-45022:-1:exon
subclass of: SO_0000010

851245
type: Gene
SIO_000068: ncbigene

position:42881:-1
position: 42881
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:45022:-1
position: 45022
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:42881-45022:-1:exon

YAL054C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: FUN44
gene: ACS1
locus tag: YAL054C
gene synonym: FUN44
product: acetate--CoA ligase 1
transcript id: NM_001178197.1
SIO_010081: YAL054C
subclass of: SO_0000673
so part of: YAL054C
location: complement(<42881..>45022)
location: region:42881-45022:-1
so has part: feature:42881-45022:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:42881-45022:-1:exon

YAL054C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: FUN44
gene: ACS1
locus tag: YAL054C
gene synonym: FUN44
EC number: 6.2.1.1
experiment: EXISTENCE:direct assay:GO:0003987 acetate-CoA ligase activity [PMID:8910545]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:9711835]
experiment: EXISTENCE:direct assay:GO:0006085 acetyl-CoA biosynthetic process [PMID:8910545]
experiment: EXISTENCE:direct assay:GO:0016880 acid-ammonia (or amide) ligase activity [PMID:18305111]
experiment: EXISTENCE:mutant phenotype:GO:0019654 acetate fermentation [PMID:1363452]
note: Acetyl-coA synthetase isoform; along with Acs2p, acetyl-coA synthetase isoform is the nuclear source of acetyl-coA for histone acetylation; expressed during growth on nonfermentable carbon sources and under aerobic conditions
codon start: 1
product: acetate--CoA ligase 1
translation: MSPSAVQSSKLEEQSSEIDKLKAKMSQSAATAQQKKEHEYEHLTSVKIVPQRPISDRLQPAIATHYSPHLDGLQDYQRLHKESIEDPAKFFGSKATQFLNWSKPFDKVFIPDPKTGRPSFQNNAWFLNGQLNACYNCVDRHALKTPNKKAIIFEGDEPGQGYSITYKELLEEVCQVAQVLTYSMGVRKGDTVAVYMPMVPEAIITLLAISRIGAIHSVVFAGFSSNSLRDRINDGDSKVVITTDESNRGGKVIETKRIVDDALRETPGVRHVLVYRKTNNPSVAFHAPRDLDWATEKKKYKTYYPCTPVDSEDPLFLLYTSGSTGAPKGVQHSTAGYLLGALLTMRYTFDTHQEDVFFTAGDIGWITGHTYVVYGPLLYGCATLVFEGTPAYPNYSRYWDIIDEHKVTQFYVAPTALRLLKRAGDSYIENHSLKSLRCLGSVGEPIAAEVWEWYSEKIGKNEIPIVDTYWQTESGSHLVTPLAGGVTPMKPGSASFPFFGIDAVVLDPNTGEELNTSHAEGVLAVKAAWPSFARTIWKNHDRYLDTYLNPYPGYYFTGDGAAKDKDGYIWILGRVDDVVNVSGHRLSTAEIEAAIIEDPIVAECAVVGFNDDLTGQAVAAFVVLKNKSSWSTATDDELQDIKKHLVFTVRKDIGPFAAPKLIILVDDLPKTRSGKIMRRILRKILAGESDQLGDVSTLSNPGIVRHLIDSVKL
SIO_010081: YAL054C
subclass of: SO_0000673
so part of: YAL054C
location: complement(42881..45022)
location: region:42881-45022:-1
so has part: feature:42881-45022:-1:exon

NP_009347.1
type: Protein
SIO_000068: ncbiprotein

S000000050
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:42881-45022:-1:exon

YAL053W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FLC2
locus tag: YAL053W
so part of: sequence
location: <45899..>48250
location: region:45899-48250:1
so has part: feature:45899-48250:1:exon
subclass of: SO_0000010

851246
type: Gene
SIO_000068: ncbigene

position:45899:1
position: 45899
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:48250:1
position: 48250
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:45899-48250:1:exon

YAL053W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FLC2
locus tag: YAL053W
product: flavin adenine dinucleotide transporter FLC2
transcript id: NM_001178196.2
SIO_010081: YAL053W
subclass of: SO_0000673
so part of: YAL053W
location: <45899..>48250
location: region:45899-48250:1
so has part: feature:45899-48250:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:45899-48250:1:exon

YAL053W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FLC2
locus tag: YAL053W
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:16717099]
experiment: EXISTENCE:genetic interaction:GO:0030148 sphingolipid biosynthetic process [PMID:27462707]
experiment: EXISTENCE:mutant phenotype:GO:0006457 protein folding [PMID:16717099]
experiment: EXISTENCE:mutant phenotype:GO:0009272 fungal-type cell wall biogenesis [PMID:16717099]
experiment: EXISTENCE:mutant phenotype:GO:0015230 FAD transmembrane transporter activity [PMID:16717099]
experiment: EXISTENCE:mutant phenotype:GO:0015883 FAD transport [PMID:16717099]
experiment: EXISTENCE:mutant phenotype:GO:0055074 calcium ion homeostasis [PMID:25573187]
experiment: EXISTENCE:mutant phenotype:GO:0055085 transmembrane transport [PMID:16717099]
experiment: EXISTENCE:mutant phenotype:GO:0071476 cellular hypotonic response [PMID:25573187]
note: Putative calcium channel involved in calcium release under hypotonic stress; required for uptake of FAD into endoplasmic reticulum; involved in cell wall maintenance; targeted to vacuole via AP-3 pathway; FLC2 has a paralog, YOR365C, that arose from the whole genome duplication
codon start: 1
product: flavin adenine dinucleotide transporter FLC2
translation: MIFLNTFARCLLTCFVLCSGTARSSDTNDTTPASAKHLQTTSLLTCMDNSQLTASFFDVKFYPDNNTVIFDIDATTTLNGNVTVKAELLTYGLKVLDKTFDLCSLGQVSLCPLSAGRIDVMSTQVIESSITKQFPGIAYTIPDLDAQVRVVAYAQNDTEFETPLACVQAILSNGKTVQTKYAAWPIAAISGVGVLTSGFVSVIGYSATAAHIASNSISLFIYFQNLAITAMMGVSRVPPIAAAWTQNFQWSMGIINTNFMQKIFDWYVQATNGVSNVVVANKDVLSISVQKRAISMASSSDYNFDTILDDSNLYTTSEKDPSNYSAKILVLRGIERVAYLANIELSNFFLTGIVFFLFFLFVVVVSLIFFKALLEVLTRARILKETSNFFQYRKNWGSIIKGTLFRLSIIAFPQVSLLAIWEFTQVNSPAIVVDAVVILLIITGLLVYGTIRVFIKGRESLRLYKNPAYLLYSDTYFLNKFGFLYVQFKADKFWWLLPLLSYAFLRSLFVAVLQNQGKAQAMIIFVIELAYFVCLCWIRPYLDKRTNVFNIAIHLVNLINAFFFLFFSNLFKQPAVVSSVMAVILFVLNAVFALFLLLFTIVTCTLALLHRNPDVRYQPMKDDRVSFIPKIQNDFDGKNKNDSELFELRKAVMDTNENEEEKMFRDDTFGKNLNANTNTARLFDDETSSSSFKQNSSPFDASEVTEQPVQPTSAVMGTGGSFLSPQYQRASSASRTNLAPNNTSTSSLMKPESSLYLGNSNKSYSHFNNNGSNENARNNNPYL
SIO_010081: YAL053W
subclass of: SO_0000673
so part of: YAL053W
location: 45899..48250
location: region:45899-48250:1
so has part: feature:45899-48250:1:exon

NP_009348.2
type: Protein
SIO_000068: ncbiprotein

S000000049
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:45899-48250:1:exon

YAL051W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YAF1
gene: OAF1
locus tag: YAL051W
gene synonym: YAF1
so part of: sequence
location: <48564..>51707
location: region:48564-51707:1
so has part: feature:48564-51707:1:exon
subclass of: SO_0000010

851247
type: Gene
SIO_000068: ncbigene

position:48564:1
position: 48564
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:51707:1
position: 51707
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:48564-51707:1:exon

YAL051W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YAF1
gene: OAF1
locus tag: YAL051W
gene synonym: YAF1
product: oleate-activated transcription factor OAF1
transcript id: NM_001178195.2
SIO_010081: YAL051W
subclass of: SO_0000673
so part of: YAL051W
location: <48564..>51707
location: region:48564-51707:1
so has part: feature:48564-51707:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:48564-51707:1:exon

YAL051W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YAF1
gene: OAF1
locus tag: YAL051W
gene synonym: YAF1
experiment: EXISTENCE:direct assay:GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding [PMID:9288897]
experiment: EXISTENCE:direct assay:GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific [PMID:10428786]
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:19111667|PMID:19158363]
experiment: EXISTENCE:direct assay:GO:0089716 Pip2-Oaf1 complex [PMID:9288897]
experiment: EXISTENCE:genetic interaction:GO:0061429 positive regulation of transcription from RNA polymerase II promoter by oleic acid [PMID:9288897]
experiment: EXISTENCE:mutant phenotype:GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding [PMID:9288897]
experiment: EXISTENCE:mutant phenotype:GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific [PMID:8972187|PMID:10428786]
experiment: EXISTENCE:mutant phenotype:GO:0032000 positive regulation of fatty acid beta-oxidation [PMID:8972187]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:8972187]
experiment: EXISTENCE:mutant phenotype:GO:0061429 positive regulation of transcription from RNA polymerase II promoter by oleic acid [PMID:9288897]
experiment: EXISTENCE:physical interaction:GO:0089716 Pip2-Oaf1 complex [PMID:8972187]
note: Oleate-activated transcription factor; subunit of a heterodimeric complex with Pip2p, which binds to oleate-response elements (ORE) in the promoter of genes involved in beta-oxidation of fatty acids, peroxisome organization and biogenesis, activating transcription in the presence of oleate; regulates chromatin silencing at telomeres; involved in diauxic shift; OAF1 has a paralog, PIP2, that arose from the whole genome duplication
codon start: 1
product: oleate-activated transcription factor OAF1
translation: MVENSTQKAPHAGNDDNSSTKPYSEAFFLGFNNPTPGLEAEHSSTSPAPENSETHNRKRNRILFVCQACRKSKTKCDREKPECGRCVKHGLKCVYDVSKQPAPRIPSKDAIISRLEKDMFYWKDKAMKLLTEREVNESGKRSASPINTNNASGDSPDTKKQHKMEPIYEQSGNGDINNGTRNDIEINLYRSHPTMIMSKVMKREVKPLSENYIIIQDCFLKILVTSVFLDTSKNTMIPALTANANITRAQPSVANNLLKLKEMLIRQCQTEDEKNRVNEFTDRILQNTNSNRNLKIGMLLSMLYNSVGYQYLEDHCPQGGEYSDLLRNLINECEAILPSYEIIERYKNHFYEYVYPSLPFIELEIFEESLSQTIFPDPNNPSKVQIRMGSTHLRAKVENLSLLLVILKLSYMSIRFLDHSTADSSFYLSKEIIDKYPIPNDFILLSQRCLASENWCACANENIISCLLYIWSFFAFSPEEGDFFLEHPTDVISSLIMMLSTSIGLHRDPSDFPQLISPSTSDKRTLNHRRILWLSIVTVCSFEASLKGRHSVSPISLMALFLNIKDPDSLTVYMNRVRGDLSDINNHKLLRIHKFTFKRAQLALLLSDLDNLTMTYYGSFHLHSIEFIREKIEIFVEENFPIVPLKSVAQDKSDLDDMNVISEMNILSSENSSSFHNRIMNKLLMLRTSMAVFLHFETLITKDKSIFPFYKKYFMVSCMDALSLINYFNKFFNGEYRHAISSLTSFNVTKFIQLALSSTIFSLLGIILRIGLAIHMLSSEVQKLSGTTDPRIKELNTKVEKFSTLQRDLESALEGIYCSASEHLRFTYFPVFKMLALFDVIVQRMRKGELWHGIFTMIQMEQMHSRIIKTLSITLGVKLDKKDRLLEELMACNHVANFSVEDIDELNRNIKKEIQISSGLKPPVNTIDLTNGEPFGNAVPTFTKTWSSSLDNLEKLSSAAAVGQSLDYNSGLRQGPLAGGGSKEQTPIAGMNNLNNSINATPIVDNSSGSQLPNGFDRGQANNTPFPGYFGGLDLFDYDFLFGNDFA
SIO_010081: YAL051W
subclass of: SO_0000673
so part of: YAL051W
location: 48564..51707
location: region:48564-51707:1
so has part: feature:48564-51707:1:exon

NP_009349.3
type: Protein
SIO_000068: ncbiprotein

S000000048
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:48564-51707:1:exon

YAL049C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: AIM2
locus tag: YAL049C
so part of: sequence
location: complement(<51855..>52595)
location: region:51855-52595:-1
so has part: feature:51855-52595:-1:exon
subclass of: SO_0000010

851248
type: Gene
SIO_000068: ncbigene

position:51855:-1
position: 51855
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:52595:-1
position: 52595
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:51855-52595:-1:exon

YAL049C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: AIM2
locus tag: YAL049C
product: protein AIM2
transcript id: NM_001178194.1
SIO_010081: YAL049C
subclass of: SO_0000673
so part of: YAL049C
location: complement(<51855..>52595)
location: region:51855-52595:-1
so has part: feature:51855-52595:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:51855-52595:-1:exon

YAL049C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: AIM2
locus tag: YAL049C
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
note: Cytoplasmic protein involved in mitochondrial function or organization; null mutant displays reduced frequency of mitochondrial genome loss; potential Hsp82p interactor
codon start: 1
product: protein AIM2
translation: MASNQPGKCCFEGVCHDGTPKGRREEIFGLDTYAAGSTSPKEKVIVILTDVYGNKFNNVLLTADKFASAGYMVFVPDILFGDAISSDKPIDRDAWFQRHSPEVTKKIVDGFMKLLKLEYDPKFIGVVGYCFGAKFAVQHISGDGGLANAAAIAHPSFVSIEEIEAIDSKKPILISAAEEDHIFPANLRHLTEEKLKDNHATYQLDLFSGVAHGFAARGDISIPAVKYAKEKVLLDQIYWFNHFSNV
SIO_010081: YAL049C
subclass of: SO_0000673
so part of: YAL049C
location: complement(51855..52595)
location: region:51855-52595:-1
so has part: feature:51855-52595:-1:exon

NP_009350.1
type: Protein
SIO_000068: ncbiprotein

S000000047
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:51855-52595:-1:exon

YAL048C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: GON1
gene: GEM1
locus tag: YAL048C
gene synonym: GON1
so part of: sequence
location: complement(<52801..>54789)
location: region:52801-54789:-1
so has part: feature:52801-54789:-1:exon
subclass of: SO_0000010

851249
type: Gene
SIO_000068: ncbigene

position:52801:-1
position: 52801
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:54789:-1
position: 54789
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:52801-54789:-1:exon

YAL048C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: GON1
gene: GEM1
locus tag: YAL048C
gene synonym: GON1
product: ERMES complex Ca(2+)-binding regulatory GTPase GEM1
transcript id: NM_001178193.1
SIO_010081: YAL048C
subclass of: SO_0000673
so part of: YAL048C
location: complement(<52801..>54789)
location: region:52801-54789:-1
so has part: feature:52801-54789:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:52801-54789:-1:exon

YAL048C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: GON1
gene: GEM1
locus tag: YAL048C
gene synonym: GON1
experiment: EXISTENCE:direct assay:GO:0005509 calcium ion binding [PMID:21036903]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005741 mitochondrial outer membrane [PMID:15479738|PMID:16407407]
experiment: EXISTENCE:genetic interaction:GO:0000001 mitochondrion inheritance [PMID:18245340]
experiment: EXISTENCE:genetic interaction:GO:0055091 phospholipid homeostasis [PMID:21825164]
experiment: EXISTENCE:mutant phenotype:GO:0000001 mitochondrion inheritance [PMID:18245340]
experiment: EXISTENCE:mutant phenotype:GO:0003924 GTPase activity [PMID:15479738]
experiment: EXISTENCE:mutant phenotype:GO:0010821 regulation of mitochondrion organization [PMID:21825164]
experiment: EXISTENCE:mutant phenotype:GO:0015886 heme transport [PMID:32265272]
experiment: EXISTENCE:mutant phenotype:GO:1990456 mitochondrion-endoplasmic reticulum membrane tethering [PMID:21825164|PMID:23682313]
experiment: EXISTENCE:physical interaction:GO:0032865 ERMES complex [PMID:21825164|PMID:21945531]
note: Outer mitochondrial membrane GTPase, subunit of the ERMES complex; potential regulatory subunit of the ERMES complex that links the ER to mitochondria and may promote inter-organellar calcium and phospholipid exchange as well as coordinating mitochondrial DNA replication and growth; cells lacking Gem1p contain collapsed, globular, or grape-like mitochondria; ortholog of metazoan Miro GTPases
codon start: 1
product: ERMES complex Ca(2+)-binding regulatory GTPase GEM1
translation: MTKETIRVVICGDEGVGKSSLIVSLTKAEFIPTIQDVLPPISIPRDFSSSPTYSPKNTVLIDTSDSDLIALDHELKSADVIWLVYCDHESYDHVSLFWLPHFRSLGLNIPVILCKNKCDSISNVNANAMVVSENSDDDIDTKVEDEEFIPILMEFKEIDTCIKTSAKTQFDLNQAFYLCQRAITHPISPLFDAMVGELKPLAVMALKRIFLLSDLNQDSYLDDNEILGLQKKCFNKSIDVNELNFIKDLLLDISKHDQEYINRKLYVPGKGITKDGFLVLNKIYAERGRHETTWAILRTFHYTDSLCINDKILHPRLVVPDTSSVELSPKGYRFLVDIFLKFDIDNDGGLNNQELHRLFKCTPGLPKLWTSTNFPFSTVVNNKGCITLQGWLAQWSMTTFLNYSTTTAYLVYFGFQEDARLALQVTKPRKMRRRSGKLYRSNINDRKVFNCFVIGKPCCGKSSLLEAFLGRSFSEEYSPTIKPRIAVNSLELKGGKQYYLILQELGEQEYAILENKDKLKECDVICLTYDSSDPESFSYLVSLLDKFTHLQDLPLVFVASKADLDKQQQRCQIQPDELADELFVNHPLHISSRWLSSLNELFIKITEAALDPGKNTPGLPEETAAKDVDYRQTALIFGSTVGFVALCSFTLMKLFKSSKFSK
SIO_010081: YAL048C
subclass of: SO_0000673
so part of: YAL048C
location: complement(52801..54789)
location: region:52801-54789:-1
so has part: feature:52801-54789:-1:exon

NP_009351.1
type: Protein
SIO_000068: ncbiprotein

S000000046
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:52801-54789:-1:exon

YAL047C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LDB4
gene: SPC72
locus tag: YAL047C
gene synonym: LDB4
so part of: sequence
location: complement(<54989..>56857)
location: region:54989-56857:-1
so has part: feature:54989-56857:-1:exon
subclass of: SO_0000010

851250
type: Gene
SIO_000068: ncbigene

position:54989:-1
position: 54989
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:56857:-1
position: 56857
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:54989-56857:-1:exon

YAL047C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LDB4
gene: SPC72
locus tag: YAL047C
gene synonym: LDB4
product: gamma-tubulin complex subunit SPC72
transcript id: NM_001178192.2
SIO_010081: YAL047C
subclass of: SO_0000673
so part of: YAL047C
location: complement(<54989..>56857)
location: region:54989-56857:-1
so has part: feature:54989-56857:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:54989-56857:-1:exon

YAL047C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LDB4
gene: SPC72
locus tag: YAL047C
gene synonym: LDB4
experiment: EXISTENCE:direct assay:GO:0005816 spindle pole body [PMID:9382872]
experiment: EXISTENCE:direct assay:GO:0005824 outer plaque of spindle pole body [PMID:9670012]
experiment: EXISTENCE:direct assay:GO:0005876 spindle microtubule [PMID:9382872]
experiment: EXISTENCE:direct assay:GO:0044877 protein-containing complex binding [PMID:12970190|PMID:9670012]
experiment: EXISTENCE:direct assay:GO:0051010 microtubule plus-end binding [PMID:12970190]
experiment: EXISTENCE:direct assay:GO:0061499 outer plaque of mitotic spindle pole body [PMID:9585415]
experiment: EXISTENCE:direct assay:GO:0099609 microtubule lateral binding [PMID:9382872]
experiment: EXISTENCE:direct assay:GO:1905721 mitotic spindle astral microtubule end [PMID:12970190]
experiment: EXISTENCE:genetic interaction:GO:0031578 mitotic spindle orientation checkpoint signaling [PMID:17967947]
experiment: EXISTENCE:mutant phenotype:GO:0007020 microtubule nucleation [PMID:18573877]
experiment: EXISTENCE:mutant phenotype:GO:0030953 astral microtubule organization [PMID:12970190]
experiment: EXISTENCE:mutant phenotype:GO:0031122 cytoplasmic microtubule organization [PMID:9606209]
experiment: EXISTENCE:mutant phenotype:GO:1990734 astral microtubule anchoring at mitotic spindle pole body [PMID:12970190]
experiment: EXISTENCE:physical interaction:GO:0031578 mitotic spindle orientation checkpoint signaling [PMID:17967947]
experiment: EXISTENCE:physical interaction:GO:0110121 gamma-tubulin complex localization to cytoplasmic side of mitotic spindle pole body [PMID:9670012]
note: Gamma-tubulin small complex (gamma-TuSC) receptor; recruits the gamma-TuSC complex to the cytoplasmic side of the SPB, connecting nuclear microtubules to the SPB; involved in astral microtubule formation, stabilization, and with Stu2p, anchoring astral MTs at the cytoplasmic face of the SPB, and regulating plus-end MT dynamics; regulated by Cdc5 kinase
codon start: 1
product: gamma-tubulin complex subunit SPC72
translation: MVRRWIPSGRHLRNNDNTGDDDDSEFTNSMDSGMSIPSLRDSMTTRSSHNDPIKPALMNDSNKVKNLEKELTNAKIKIQVLYEYIRRIPNKDGNAPSLGNDTDFRNSIIEGLNLEINKLKQDLKAKEVEYQDTLQFVQENLENSESIVNTINHLLSFILTHFNEQDENAHLLDKEERETLEETLELSSDYVLEKMDTLSKFIIQFLQDFLHSKSRAESKQDKEEFLSLAQSSPAGSQLESRDSPSSKEENTDGGYQNDEIHDSNNHIDTENVMANSTSLPISAVESRFEKTLDTQLEIVIENLHKEYDQFINSIRLKFEKSQKLEKIIASKLNEQSHLLDSLELEENSSSVIEKQDHLISQLKEKIESQSVLINNLEKLKEDIIKMKQNEKVLTKELETQTKINKLKENNWDSYINDLEKQINDLQIDKSEEFHVIQNQLDKLDLENYQLKNQLNTLDNQKLILSQYESNFIKFNQNLLLHLDSIFNILQKILQESSIAQFDRKMKSIKSVPNALKNLNLIQPKLESLYTFIETALESIINSYISSLISMETPEQPHQQGNELTATPNKELTLRIEELQRRWISERERRKLDANASEARIKALEQENESLRSKLFNLSINNP
SIO_010081: YAL047C
subclass of: SO_0000673
so part of: YAL047C
location: complement(54989..56857)
location: region:54989-56857:-1
so has part: feature:54989-56857:-1:exon

NP_009352.2
type: Protein
SIO_000068: ncbiprotein

S000000045
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:54989-56857:-1:exon

YAL046C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: AIM1
gene: BOL3
locus tag: YAL046C
gene synonym: AIM1
so part of: sequence
location: complement(<57029..>57385)
location: region:57029-57385:-1
so has part: feature:57029-57385:-1:exon
subclass of: SO_0000010

851251
type: Gene
SIO_000068: ncbigene

position:57029:-1
position: 57029
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:57385:-1
position: 57385
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:57029-57385:-1:exon

YAL046C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: AIM1
gene: BOL3
locus tag: YAL046C
gene synonym: AIM1
product: Bol3p
transcript id: NM_001178191.1
SIO_010081: YAL046C
subclass of: SO_0000673
so part of: YAL046C
location: complement(<57029..>57385)
location: region:57029-57385:-1
so has part: feature:57029-57385:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:57029-57385:-1:exon

YAL046C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: AIM1
gene: BOL3
locus tag: YAL046C
gene synonym: AIM1
experiment: EXISTENCE:direct assay:GO:0005759 mitochondrial matrix [PMID:27532772]
experiment: EXISTENCE:genetic interaction:GO:0106035 protein maturation by [4Fe-4S] cluster transfer [PMID:27532772|PMID:27532773]
experiment: EXISTENCE:mutant phenotype:GO:0106035 protein maturation by [4Fe-4S] cluster transfer [PMID:27532772]
experiment: EXISTENCE:physical interaction:GO:0106035 protein maturation by [4Fe-4S] cluster transfer [PMID:27532773]
note: Protein involved in Fe-S cluster transfer to mitochondrial clients; protects [4Fe-4S] clusters from damage due to oxidative stress by acting along with Nfu1p at a late step in the transfer of [4Fe-4S] clusters from the ISA complex to mitochondrial client proteins like lipoate synthase and succinate dehydrogenase; sequence similarity to human BOLA family member, BOLA3, mutations of which are associated with Multiple Mitochondria Dysfunctions Syndrome (MMDS2)
codon start: 1
product: Bol3p
translation: MKLPQTMLRSISVKHVRWPRILTGSKLWYSTQMAMTPEEKMITDKLQQELEPEVCKVQDVSGGCGSMFAINITSKKFNGLSLIKQHQLVNRILRDDISRWHGLQLTTKKSTGKGPASS
SIO_010081: YAL046C
subclass of: SO_0000673
so part of: YAL046C
location: complement(57029..57385)
location: region:57029-57385:-1
so has part: feature:57029-57385:-1:exon

NP_009353.1
type: Protein
SIO_000068: ncbiprotein

S000000044
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:57029-57385:-1:exon

YAL044W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: BOL1
locus tag: YAL044W-A
so part of: sequence
location: <57518..>57850
location: region:57518-57850:1
so has part: feature:57518-57850:1:exon
subclass of: SO_0000010

851252
type: Gene
SIO_000068: ncbigene

position:57518:1
position: 57518
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:57850:1
position: 57850
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:57518-57850:1:exon

YAL044W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: BOL1
locus tag: YAL044W-A
product: Bol1p
transcript id: NM_001184453.1
SIO_010081: YAL044W-A
subclass of: SO_0000673
so part of: YAL044W-A
location: <57518..>57850
location: region:57518-57850:1
so has part: feature:57518-57850:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:57518-57850:1:exon

YAL044W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: BOL1
locus tag: YAL044W-A
experiment: EXISTENCE:direct assay:GO:0005759 mitochondrial matrix [PMID:27532772]
experiment: EXISTENCE:genetic interaction:GO:0044572 [4Fe-4S] cluster assembly [PMID:27532773]
experiment: EXISTENCE:genetic interaction:GO:0106035 protein maturation by [4Fe-4S] cluster transfer [PMID:27532772]
experiment: EXISTENCE:mutant phenotype:GO:0044572 [4Fe-4S] cluster assembly [PMID:27532773]
experiment: EXISTENCE:physical interaction:GO:0044572 [4Fe-4S] cluster assembly [PMID:27532773]
note: Mitochondrial matrix protein involved in Fe-S cluster biogenesis; facilitates [4Fe-2S] cluster inception into mitochondrial proteins such as lipoate synthase and succinate dehydrogenase; interacts and may function with Grx5p at an early step in Fe-S cluster biosynthesis; forms dimeric complexes with Grx5p and Nfu1p that alter the stability of shared Fe/S clusters; sequence similarity to human BOLA family member, BOLA1 and S. pombe uvi31, a putative DNA repair protein
codon start: 1
product: Bol1p
translation: MFKRAMSTDGPVARTILKRLECGFPDYKNFAFGLYNDSHKHKGHAGVQGNVSAETHFRIEMVSKKFEGLKLPQRHRMVYSLLQDEMAQANGIHALQLSLKTPQEYESKAK
SIO_010081: YAL044W-A
subclass of: SO_0000673
so part of: YAL044W-A
location: 57518..57850
location: region:57518-57850:1
so has part: feature:57518-57850:1:exon

NP_075206.1
type: Protein
SIO_000068: ncbiprotein

S000007586
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:57518-57850:1:exon

YAL044C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: GCV3
locus tag: YAL044C
so part of: sequence
location: complement(<57950..>58462)
location: region:57950-58462:-1
so has part: feature:57950-58462:-1:exon
subclass of: SO_0000010

851254
type: Gene
SIO_000068: ncbigene

position:57950:-1
position: 57950
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:58462:-1
position: 58462
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:57950-58462:-1:exon

YAL044C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: GCV3
locus tag: YAL044C
product: glycine decarboxylase subunit H
transcript id: NM_001178189.1
SIO_010081: YAL044C
subclass of: SO_0000673
so part of: YAL044C
location: complement(<57950..>58462)
location: region:57950-58462:-1
so has part: feature:57950-58462:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:57950-58462:-1:exon

YAL044C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: GCV3
locus tag: YAL044C
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:19570983|PMID:14576278|PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0031405 lipoic acid binding [PMID:32974306]
experiment: EXISTENCE:genetic interaction:GO:0006730 one-carbon metabolic process [PMID:10871621]
experiment: EXISTENCE:mutant phenotype:GO:0005960 glycine cleavage complex [PMID:9020168]
experiment: EXISTENCE:mutant phenotype:GO:0006546 glycine catabolic process [PMID:9020168]
experiment: EXISTENCE:mutant phenotype:GO:0009249 protein lipoylation [PMID:19570983]
note: H subunit of the mitochondrial glycine decarboxylase complex; glycine decarboxylase is required for the catabolism of glycine to 5,10-methylene-THF; also required for all protein lipoylation; expression is regulated by levels of 5,10-methylene-THF
codon start: 1
product: glycine decarboxylase subunit H
translation: MLRTTRLWTTRMPTVSKLFLRNSSGNALNKNKLPFLYSSQGPQAVRYTSQHEWIAVHQDKTAFVGITKYATDALGDATYVELPEVGTEIAQGESLGSIESVKSASEIYQPADGTVEEINTNLEENPGVVNEDPMGDGWLVKMKLGEGVNVEQVEGLMSLEQYEKTLVHDD
SIO_010081: YAL044C
subclass of: SO_0000673
so part of: YAL044C
location: complement(57950..58462)
location: region:57950-58462:-1
so has part: feature:57950-58462:-1:exon

NP_009355.3
type: Protein
SIO_000068: ncbiprotein

S000000042
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:57950-58462:-1:exon

YAL043C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: FUN39
gene: PTA1
locus tag: YAL043C
gene synonym: FUN39
so part of: sequence
location: complement(<58695..>61052)
location: region:58695-61052:-1
so has part: feature:58695-61052:-1:exon
subclass of: SO_0000010

851255
type: Gene
SIO_000068: ncbigene

position:58695:-1
position: 58695
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:61052:-1
position: 61052
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:58695-61052:-1:exon

YAL043C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: FUN39
gene: PTA1
locus tag: YAL043C
gene synonym: FUN39
product: RNA-processing protein PTA1
transcript id: NM_001178188.1
SIO_010081: YAL043C
subclass of: SO_0000673
so part of: YAL043C
location: complement(<58695..>61052)
location: region:58695-61052:-1
so has part: feature:58695-61052:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:58695-61052:-1:exon

YAL043C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: FUN39
gene: PTA1
locus tag: YAL043C
gene synonym: FUN39
experiment: EXISTENCE:curator inference:GO:0003723 RNA binding [PMID:10523662]
experiment: EXISTENCE:direct assay:GO:0005847 mRNA cleavage and polyadenylation specificity factor complex [PMID:10523662|PMID:12819204|PMID:9099738]
experiment: EXISTENCE:mutant phenotype:GO:0006378 mRNA polyadenylation [PMID:10523662|PMID:9303317]
experiment: EXISTENCE:mutant phenotype:GO:0008033 tRNA processing [PMID:1508188]
experiment: EXISTENCE:mutant phenotype:GO:0098789 pre-mRNA cleavage required for polyadenylation [PMID:10523662]
experiment: EXISTENCE:physical interaction:GO:0030846 termination of RNA polymerase II transcription, poly(A)-coupled [PMID:12819204]
note: Subunit of holo-CPF; holo-CPF is a multiprotein complex and functional homolog of mammalian CPSF, required for the cleavage and polyadenylation of mRNA and snoRNA 3' ends; involved in pre-tRNA processing; binds to the phosphorylated CTD of RNAPII
codon start: 1
product: RNA-processing protein PTA1
translation: MSSAEMEQLLQAKTLAMHNNPTEMLPKVLETTASMYHNGNLSKLKLPLAKFFTQLVLDVVSMDSPIANTERPFIAAQYLPLLLAMAQSTADVLVYKNIVLIMCASYPLVLDLVAKTSNQEMFDQLCMLKKFVLSHWRTAYPLRATVDDETDVEQWLAQIDQNIGVKLATIKFISEVVLSQTKSPSGNEINSSTIPDNHPVLNKPALESEAKRLLDMLLNYLIEEQYMVSSVFIGIINSLSFVIKRRPQTTIRILSGLLRFNVDAKFPLEGKSDLNYKLSKRFVERAYKNFVQFGLKNQIITKSLSSGSGSSIYSKLTKISQTLHVIGEETKSKGILNFDPSKGNSKKTLSRQDKLKYISLWKRQLSALLSTLGVSTKTPTPVSAPATGSSTENMLDQLKILQKYTLNKASHQGNTFFNNSPKPISNTYSSVYSLMNSSNSNQDVTQLPNDILIKLSTEAILQMDSTKLITGLSIVASRYTDLMNTYINSVPSSSSSKRKSDDDDDGNDNEEVGNDGPTANSKKIKMETEPLAEEPEEPEDDDRMQKMLQEEESAQEISGDANKSTSAIKEIAPPFEPDSLTQDEKLKYLSKLTKKLFELSGRQDTTRAKSSSSSSILLDDDDSSSWLHVLIRLVTRGIEAQEASDLIREELLGFFIQDFEQRVSLIIEWLNEEWFFQTSLHQDPSNYKKWSLRVLESLGPFLENKHRRFFIRLMSELPSLQSDHLEALKPICLDPARSSLGFQTLKFLIMFRPPVQDTVRDLLHQLKQEDEGLHKQCDSLLDRLK
SIO_010081: YAL043C
subclass of: SO_0000673
so part of: YAL043C
location: complement(58695..61052)
location: region:58695-61052:-1
so has part: feature:58695-61052:-1:exon

NP_009356.1
type: Protein
SIO_000068: ncbiprotein

S000000041
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:58695-61052:-1:exon

YAL042W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: FUN9
gene: ERV46
locus tag: YAL042W
gene synonym: FUN9
so part of: sequence
location: <61316..>62563
location: region:61316-62563:1
so has part: feature:61316-62563:1:exon
subclass of: SO_0000010

851256
type: Gene
SIO_000068: ncbigene

position:61316:1
position: 61316
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:62563:1
position: 62563
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:61316-62563:1:exon

YAL042W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: FUN9
gene: ERV46
locus tag: YAL042W
gene synonym: FUN9
product: Erv46p
transcript id: NM_001178187.1
SIO_010081: YAL042W
subclass of: SO_0000673
so part of: YAL042W
location: <61316..>62563
location: region:61316-62563:1
so has part: feature:61316-62563:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:61316-62563:1:exon

YAL042W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: FUN9
gene: ERV46
locus tag: YAL042W
gene synonym: FUN9
experiment: EXISTENCE:direct assay:GO:0000139 Golgi membrane [PMID:11157978]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005789 endoplasmic reticulum membrane [PMID:11157978]
experiment: EXISTENCE:direct assay:GO:0030134 COPII-coated ER to Golgi transport vesicle [PMID:11157978]
experiment: EXISTENCE:genetic interaction:GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport [PMID:11157978]
note: Protein localized to COPII-coated vesicles; forms a complex with Erv41p; involved in the membrane fusion stage of transport
codon start: 1
product: Erv46p
translation: MKRSTLLSLDAFAKTEEDVRVRTRAGGLITLSCILTTLFLLVNEWGQFNSVVTRPQLVVDRDRHAKLELNMDVTFPSMPCDLVNLDIMDDSGEMQLDILDAGFTMSRLNSEGRPVGDATELHVGGNGDGTAPVNNDPNYCGPCYGAKDQSQNENLAQEEKVCCQDCDAVRSAYLEAGWAFFDGKNIEQCEREGYVSKINEHLNEGCRIKGSAQINRIQGNLHFAPGKPYQNAYGHFHDTSLYDKTSNLNFNHIINHLSFGKPIQSHSKLLGNDKRHGGAVVATSPLDGRQVFPDRNTHFHQFSYFAKIVPTRYEYLDNVVIETAQFSATFHSRPLAGGRDKDHPNTLHVRGGIPGMFVFFEMSPLKVINKEQHGQTWSGFILNCITSIGGVLAVGTVMDKLFYKAQRSIWGKKSQ
SIO_010081: YAL042W
subclass of: SO_0000673
so part of: YAL042W
location: 61316..62563
location: region:61316-62563:1
so has part: feature:61316-62563:1:exon

NP_009358.1
type: Protein
SIO_000068: ncbiprotein

S000000040
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:61316-62563:1:exon

YAL041W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CLS4
gene: CDC24
locus tag: YAL041W
gene synonym: CLS4
so part of: sequence
location: <62840..>65404
location: region:62840-65404:1
so has part: feature:62840-65404:1:exon
subclass of: SO_0000010

851190
type: Gene
SIO_000068: ncbigene

position:62840:1
position: 62840
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:65404:1
position: 65404
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:62840-65404:1:exon

YAL041W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CLS4
gene: CDC24
locus tag: YAL041W
gene synonym: CLS4
product: Rho family guanine nucleotide exchange factor CDC24
transcript id: NM_001178186.1
SIO_010081: YAL041W
subclass of: SO_0000673
so part of: YAL041W
location: <62840..>65404
location: region:62840-65404:1
so has part: feature:62840-65404:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:62840-65404:1:exon

YAL041W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CLS4
gene: CDC24
locus tag: YAL041W
gene synonym: CLS4
experiment: EXISTENCE:direct assay:GO:0000131 incipient cellular bud site [PMID:10655592]
experiment: EXISTENCE:direct assay:GO:0005085 guanyl-nucleotide exchange factor activity [PMID:8300560]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:10655592|PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:10655592|PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005934 cellular bud tip [PMID:10655592]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:10087263]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:10087263]
experiment: EXISTENCE:direct assay:GO:0120171 Cdc24p-Far1p-Gbetagamma complex [PMID:10087263]
experiment: EXISTENCE:genetic interaction:GO:0000750 pheromone-dependent signal transduction involved in conjugation with cellular fusion [PMID:7565673]
experiment: EXISTENCE:mutant phenotype:GO:0000282 cellular bud site selection [PMID:7019215]
experiment: EXISTENCE:mutant phenotype:GO:0000750 pheromone-dependent signal transduction involved in conjugation with cellular fusion [PMID:7565673]
experiment: EXISTENCE:mutant phenotype:GO:0007096 regulation of exit from mitosis [PMID:12234925]
experiment: EXISTENCE:mutant phenotype:GO:0031106 septin ring organization [PMID:16371506]
experiment: EXISTENCE:mutant phenotype:GO:0043577 chemotropism [PMID:9428768]
experiment: EXISTENCE:mutant phenotype:GO:0072697 protein localization to cell cortex [PMID:16325503]
experiment: EXISTENCE:physical interaction:GO:0120171 Cdc24p-Far1p-Gbetagamma complex [PMID:10087263]
note: Guanine nucleotide exchange factor (GEF) for Cdc42p; required for polarity establishment and maintenance, and mutants have morphological defects in bud formation and shmooing; relocalizes from nucleus to cytoplasm upon DNA replication stress; thermosensitivity of the cdc24-4 mutant in the presence of sorbitol is functionally complemented by human CDC42
codon start: 1
product: Rho family guanine nucleotide exchange factor CDC24
translation: MAIQTRFASGTSLSDLKPKPSATSISIPMQNVMNKPVTEQDSLFHICANIRKRLEVLPQLKPFLQLAYQSSEVLSERQSLLLSQKQHQELLKSNGANRDSSDLAPTLRSSSISTATSLMSMEGISYTNSNPSATPNMEDTLLTFSMGILPITMDCDPVTQLSQLFQQGAPLCILFNSVKPQFKLPVIASDDLKVCKKSIYDFILGCKKHFAFNDEELFTISDVFANSTSQLVKVLEVVETLMNSSPTIFPSKSKTQQIMNAENQHRHQPQQSSKKHNEYVKIIKEFVATERKYVHDLEILDKYRQQLLDSNLITSEELYMLFPNLGDAIDFQRRFLISLEINALVEPSKQRIGALFMHSKHFFKLYEPWSIGQNAAIEFLSSTLHKMRVDESQRFIINNKLELQSFLYKPVQRLCRYPLLVKELLAESSDDNNTKELEAALDISKNIARSINENQRRTENHQVVKKLYGRVVNWKGYRISKFGELLYFDKVFISTTNSSSEPEREFEVYLFEKIIILFSEVVTKKSASSLILKKKSSTSASISASNITDNNGSPHHSYHKRHSNSSSSNNIHLSSSSAAAIIHSSTNSSDNNSNNSSSSSLFKLSANEPKLDLRGRIMIMNLNQIIPQNNRSLNITWESIKEQGNFLLKFKNEETRDNWSSCLQQLIHDLKNEQFKARHHSSTSTTSSTAKSSSMMSPTTTMNTPNHHNSRQTHDSMASFSSSHMKRVSDVLPKRRTTSSSFESEIKSISENFKNSIPESSILFRISYNNNSNNTSSSEIFTLLVEKVWNFDDLIMAINSKISNTHNNNISPITKIKYQDEDGDFVVLGSDEDWNVAKEMLAENNEKFLNIRLY
SIO_010081: YAL041W
subclass of: SO_0000673
so part of: YAL041W
location: 62840..65404
location: region:62840-65404:1
so has part: feature:62840-65404:1:exon

NP_009359.1
type: Protein
SIO_000068: ncbiprotein

S000000039
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:62840-65404:1:exon

YAL040C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: DAF1
alternative label: FUN10
alternative label: WHI1
gene: CLN3
locus tag: YAL040C
gene synonym: DAF1; FUN10; WHI1
so part of: sequence
location: complement(<65778..>67520)
location: region:65778-67520:-1
so has part: feature:65778-67520:-1:exon
subclass of: SO_0000010

851191
type: Gene
SIO_000068: ncbigene

position:65778:-1
position: 65778
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:67520:-1
position: 67520
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:65778-67520:-1:exon

YAL040C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: DAF1
alternative label: FUN10
alternative label: WHI1
gene: CLN3
locus tag: YAL040C
gene synonym: DAF1; FUN10; WHI1
product: cyclin CLN3
transcript id: NM_001178185.1
SIO_010081: YAL040C
subclass of: SO_0000673
so part of: YAL040C
location: complement(<65778..>67520)
location: region:65778-67520:-1
so has part: feature:65778-67520:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:65778-67520:-1:exon

YAL040C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: DAF1
alternative label: FUN10
alternative label: WHI1
gene: CLN3
locus tag: YAL040C
gene synonym: DAF1; FUN10; WHI1
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:11509671|PMID:11792824|PMID:10611233]
experiment: EXISTENCE:direct assay:GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity [PMID:1316273]
experiment: EXISTENCE:direct assay:GO:0042144 vacuole fusion, non-autophagic [PMID:14573462]
experiment: EXISTENCE:genetic interaction:GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle [PMID:19823668]
experiment: EXISTENCE:genetic interaction:GO:0007089 traversing start control point of mitotic cell cycle [PMID:2147225|PMID:2574633]
experiment: EXISTENCE:mutant phenotype:GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity [PMID:1316273|PMID:8387915]
experiment: EXISTENCE:mutant phenotype:GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle [PMID:19823668]
experiment: EXISTENCE:mutant phenotype:GO:0005634 nucleus [PMID:11509671]
experiment: EXISTENCE:mutant phenotype:GO:0007033 vacuole organization [PMID:14573462]
experiment: EXISTENCE:mutant phenotype:GO:0007089 traversing start control point of mitotic cell cycle [PMID:2907481|PMID:3062366]
experiment: EXISTENCE:mutant phenotype:GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity [PMID:1316273|PMID:8387915]
experiment: EXISTENCE:mutant phenotype:GO:0042144 vacuole fusion, non-autophagic [PMID:14573462]
note: G1 cyclin involved in cell cycle progression; activates Cdc28p kinase to promote G1 to S phase transition; plays a role in regulating transcription of other G1 cyclins, CLN1 and CLN2; regulated by phosphorylation and proteolysis; acetyl-CoA induces CLN3 transcription in response to nutrient repletion to promote cell-cycle entry; cell cycle arrest phenotype of the cln1 cln2 cln3 triple null mutant is complemented by any of human cyclins CCNA2, CCNB1, CCNC, CCND1, or CCNE1
codon start: 1
product: cyclin CLN3
translation: MAILKDTIIRYANARYATASGTSTATAASVSAASCPNLPLLLQKRRAIASAKSKNPNLVKRELQAHHSAISEYNNDQLDHYFRLSHTERPLYNLTNFNSQPQVNPKMRFLIFDFIMYCHTRLNLSTSTLFLTFTILDKYSSRFIIKSYNYQLLSLTALWISSKFWDSKNRMATLKVLQNLCCNQYSIKQFTTMEMHLFKSLDWSICQSATFDSYIDIFLFQSTSPLSPGVVLSAPLEAFIQQKLALLNNAAGTAINKSSSSQGPSLNINEIKLGAIMLCELASFNLELSFKYDRSLIALGAINLIKLSLNYYNSNLWENINLALEENCQDLDIKLSEISNTLLDIAMDQNSFPSSFKSKYLNSNKTSLAKSLLDALQNYCIQLKLEEFYRSQELETMYNTIFAQSFDSDSLTCVYSNATTPKSATVSSAATDYFSDHTHLRRLTKDSISPPFAFTPTSSSSSPSPFNSPYKTSSSMTTPDSASHHSHSGSFSSTQNSFKRSLSIPQNSSIFWPSPLTPTTPSLMSNRKLLQNLSVRSKRLFPVRPMATAHPCSAPTQLKKRSTSSVDCDFNDSSNLKKTR
SIO_010081: YAL040C
subclass of: SO_0000673
so part of: YAL040C
location: complement(65778..67520)
location: region:65778-67520:-1
so has part: feature:65778-67520:-1:exon

NP_009360.1
type: Protein
SIO_000068: ncbiprotein

S000000038
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:65778-67520:-1:exon

regulatory
type: Feature
subclass of: SO_0000001
RO_0002162: 559292
regulatory class: other
note: Upstream open reading frame (uORF) in 5' untranslated region of CLN3 gene, regulate translation
so part of: sequence
location: complement(67825..67836)
location: region:67825-67836:-1
so has part: feature:67825-67836:-1:region

position:67825:-1
position: 67825
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:67836:-1
position: 67836
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:67825-67836:-1:region

YAL039C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: CYC3
locus tag: YAL039C
so part of: sequence
location: complement(<68716..>69525)
location: region:68716-69525:-1
so has part: feature:68716-69525:-1:exon
subclass of: SO_0000010

851192
type: Gene
SIO_000068: ncbigene

position:68716:-1
position: 68716
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:69525:-1
position: 69525
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:68716-69525:-1:exon

YAL039C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: CYC3
locus tag: YAL039C
product: holocytochrome c synthase CYC3
transcript id: NM_001178184.1
SIO_010081: YAL039C
subclass of: SO_0000673
so part of: YAL039C
location: complement(<68716..>69525)
location: region:68716-69525:-1
so has part: feature:68716-69525:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:68716-69525:-1:exon

YAL039C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: CYC3
locus tag: YAL039C
EC number: 4.4.1.17
experiment: EXISTENCE:direct assay:GO:0004408 holocytochrome-c synthase activity [PMID:3034577]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:24769239]
experiment: EXISTENCE:direct assay:GO:0005758 mitochondrial intermembrane space [PMID:1656231]
experiment: EXISTENCE:direct assay:GO:0018063 cytochrome c-heme linkage [PMID:3034577]
note: Cytochrome c heme lyase (holocytochrome c synthase); attaches heme to apo-cytochrome c (Cyc1p or Cyc7p) in mitochondrial intermembrane space; human homolog HCCS implicated in microphthalmia with linear skin defects (MLS), and can complement yeast null mutant
codon start: 1
product: holocytochrome c synthase CYC3
translation: MGWFWADQKTTGKDIGGAAVSSMSGCPVMHESSSSSPPSSECPVMQGDNDRINPLNNMPELAASKQPGQKMDLPVDRTISSIPKSPDSNEFWEYPSPQQMYNAMVRKGKIGGSGEVAEDAVESMVQVHNFLNEGCWQEVLEWEKPHTDESHVQPKLLKFMGKPGVLSPRARWMHLCGLLFPSHFSQELPFDRHDWIVLRGERKAEQQPPTFKEVRYVLDFYGGPDDENGMPTFHVDVRPALDSLDNAKDRMTRFLDRMISGPSSSSSAP
SIO_010081: YAL039C
subclass of: SO_0000673
so part of: YAL039C
location: complement(68716..69525)
location: region:68716-69525:-1
so has part: feature:68716-69525:-1:exon

NP_009361.1
type: Protein
SIO_000068: ncbiprotein

S000000037
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:68716-69525:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS106; Autonomously Replicating Sequence
so part of: sequence
location: 70300..70469
location: region:70300-70469:1
so has part: feature:70300-70469:1:region

S000118318
type: SGD
SIO_000068: sgd

position:70300:1
position: 70300
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:70469:1
position: 70469
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:70300-70469:1:region

YAL038W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: PYK1
gene: CDC19
locus tag: YAL038W
gene synonym: PYK1
so part of: sequence
location: <71786..>73288
location: region:71786-73288:1
so has part: feature:71786-73288:1:exon
subclass of: SO_0000010

851193
type: Gene
SIO_000068: ncbigene

position:71786:1
position: 71786
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:73288:1
position: 73288
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:71786-73288:1:exon

YAL038W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: PYK1
gene: CDC19
locus tag: YAL038W
gene synonym: PYK1
product: pyruvate kinase CDC19
transcript id: NM_001178183.1
SIO_010081: YAL038W
subclass of: SO_0000673
so part of: YAL038W
location: <71786..>73288
location: region:71786-73288:1
so has part: feature:71786-73288:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:71786-73288:1:exon

YAL038W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: PYK1
gene: CDC19
locus tag: YAL038W
gene synonym: PYK1
EC number: 2.7.1.40
experiment: EXISTENCE:direct assay:GO:0004743 pyruvate kinase activity [PMID:12063246]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14718557|PMID:27385335]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:16622836]
experiment: EXISTENCE:mutant phenotype:GO:0004743 pyruvate kinase activity [PMID:323230]
experiment: EXISTENCE:mutant phenotype:GO:0006090 pyruvate metabolic process [PMID:323230]
experiment: EXISTENCE:mutant phenotype:GO:0006096 glycolytic process [PMID:323230]
note: Pyruvate kinase; functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvate, the input for aerobic (TCA cycle) or anaerobic (glucose fermentation) respiration; regulated via allosteric activation by fructose bisphosphate; CDC19 has a paralog, PYK2, that arose from the whole genome duplication
codon start: 1
product: pyruvate kinase CDC19
translation: MSRLERLTSLNVVAGSDLRRTSIIGTIGPKTNNPETLVALRKAGLNIVRMNFSHGSYEYHKSVIDNARKSEELYPGRPLAIALDTKGPEIRTGTTTNDVDYPIPPNHEMIFTTDDKYAKACDDKIMYVDYKNITKVISAGRIIYVDDGVLSFQVLEVVDDKTLKVKALNAGKICSHKGVNLPGTDVDLPALSEKDKEDLRFGVKNGVHMVFASFIRTANDVLTIREVLGEQGKDVKIIVKIENQQGVNNFDEILKVTDGVMVARGDLGIEIPAPEVLAVQKKLIAKSNLAGKPVICATQMLESMTYNPRPTRAEVSDVGNAILDGADCVMLSGETAKGNYPINAVTTMAETAVIAEQAIAYLPNYDDMRNCTPKPTSTTETVAASAVAAVFEQKAKAIIVLSTSGTTPRLVSKYRPNCPIILVTRCPRAARFSHLYRGVFPFVFEKEPVSDWTDDVEARINFGIEKAKEFGILKKGDTYVSIQGFKAGAGHSNTLQVSTV
SIO_010081: YAL038W
subclass of: SO_0000673
so part of: YAL038W
location: 71786..73288
location: region:71786-73288:1
so has part: feature:71786-73288:1:exon

NP_009362.1
type: Protein
SIO_000068: ncbiprotein

S000000036
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:71786-73288:1:exon

YAL037C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YAL037C-A
so part of: sequence
location: complement(<73426..>73518)
location: region:73426-73518:-1
so has part: feature:73426-73518:-1:exon
subclass of: SO_0000010

1466428
type: Gene
SIO_000068: ncbigene

position:73426:-1
position: 73426
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:73518:-1
position: 73518
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:73426-73518:-1:exon

YAL037C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YAL037C-A
product: uncharacterized protein
transcript id: NM_001184629.1
SIO_010081: YAL037C-A
subclass of: SO_0000673
so part of: YAL037C-A
location: complement(<73426..>73518)
location: region:73426-73518:-1
so has part: feature:73426-73518:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:73426-73518:-1:exon

YAL037C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YAL037C-A
codon start: 1
product: uncharacterized protein
translation: MSISFPKMQHLIVMTTIGDKKVNNNIILFL
SIO_010081: YAL037C-A
subclass of: SO_0000673
so part of: YAL037C-A
location: complement(73426..73518)
location: region:73426-73518:-1
so has part: feature:73426-73518:-1:exon

NP_878040.1
type: Protein
SIO_000068: ncbiprotein

S000028732
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:73426-73518:-1:exon

YAL037W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YAL037W
so part of: sequence
location: <74020..>74823
location: region:74020-74823:1
so has part: feature:74020-74823:1:exon
subclass of: SO_0000010

851194
type: Gene
SIO_000068: ncbigene

position:74020:1
position: 74020
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:74823:1
position: 74823
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:74020-74823:1:exon

YAL037W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YAL037W
product: uncharacterized protein
transcript id: NM_001178182.1
SIO_010081: YAL037W
subclass of: SO_0000673
so part of: YAL037W
location: <74020..>74823
location: region:74020-74823:1
so has part: feature:74020-74823:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:74020-74823:1:exon

YAL037W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YAL037W
note: hypothetical protein; YAL037W has a paralog, YOR342C, that arose from the whole genome duplication
codon start: 1
product: uncharacterized protein
translation: MDMEIEDSSPIDDLKLQKLDTNVYFGPCEILTQPILLQYENIKFIIGVNLSTEKIASFYTQYFRNSNSVVVNLCSPTTAAVATKKAAIDLYIRNNTILLQKFVGQYLQMGKKIKTSLTQAQTDTIQSLPQFCNSNVLSGEPLVQYQAFNDLLALFKSFSHFGNILVISSHSYDCALLKFLISRVMTYYPLVTIQDSLQYMKATLNISISTSDEFDILNDKELWEFGQTQEILKRRQTSSVKRRCVNLPENSTIDNRMLMGTTKRGRF
SIO_010081: YAL037W
subclass of: SO_0000673
so part of: YAL037W
location: 74020..74823
location: region:74020-74823:1
so has part: feature:74020-74823:1:exon

NP_009363.1
type: Protein
SIO_000068: ncbiprotein

S000000035
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:74020-74823:1:exon

YAL036C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: FUN11
gene: RBG1
locus tag: YAL036C
gene synonym: FUN11
so part of: sequence
location: complement(<75043..>76152)
location: region:75043-76152:-1
so has part: feature:75043-76152:-1:exon
subclass of: SO_0000010

851195
type: Gene
SIO_000068: ncbigene

position:75043:-1
position: 75043
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:76152:-1
position: 76152
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:75043-76152:-1:exon

YAL036C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: FUN11
gene: RBG1
locus tag: YAL036C
gene synonym: FUN11
product: GTP-binding protein RBG1
transcript id: NM_001178181.1
SIO_010081: YAL036C
subclass of: SO_0000673
so part of: YAL036C
location: complement(<75043..>76152)
location: region:75043-76152:-1
so has part: feature:75043-76152:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:75043-76152:-1:exon

YAL036C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: FUN11
gene: RBG1
locus tag: YAL036C
gene synonym: FUN11
experiment: EXISTENCE:direct assay:GO:0005525 GTP binding [PMID:23002146]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005777 peroxisome [PMID:36164978]
experiment: EXISTENCE:direct assay:GO:0005844 polysome [PMID:19448108|PMID:23002146]
experiment: EXISTENCE:direct assay:GO:0010494 cytoplasmic stress granule [PMID:26777405]
experiment: EXISTENCE:genetic interaction:GO:0002181 cytoplasmic translation [PMID:21076151]
experiment: EXISTENCE:genetic interaction:GO:1903833 positive regulation of cellular response to amino acid starvation [PMID:23899355]
note: Member of the DRG family of GTP-binding proteins; associates with translating ribosomes; interacts with Tma46p, Ygr250cp, Gir2p and Yap1p via two-hybrid; localizes to cytosol and peroxisomes
codon start: 1
product: GTP-binding protein RBG1
translation: MSTTVEKIKAIEDEMARTQKNKATSFHLGQLKAKLAKLRRELLTSASSGSGGGAGIGFDVARTGVASVGFVGFPSVGKSTLLSKLTGTESEAAEYEFTTLVTVPGVIRYKGAKIQMLDLPGIIDGAKDGRGRGKQVIAVARTCNLLFIILDVNKPLHHKQIIEKELEGVGIRLNKTPPDILIKKKEKGGISITNTVPLTHLGNDEIRAVMSEYRINSAEIAFRCDATVDDLIDVLEASSRRYMPAIYVLNKIDSLSIEELELLYRIPNAVPISSGQDWNLDELLQVMWDRLNLVRIYTKPKGQIPDFTDPVVLRSDRCSVKDFCNQIHKSLVDDFRNALVYGSSVKHQPQYVGLSHILEDEDVVTILKK
SIO_010081: YAL036C
subclass of: SO_0000673
so part of: YAL036C
location: complement(75043..76152)
location: region:75043-76152:-1
so has part: feature:75043-76152:-1:exon

NP_009364.1
type: Protein
SIO_000068: ncbiprotein

S000000034
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:75043-76152:-1:exon

YAL035W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: yIF2
gene: FUN12
locus tag: YAL035W
gene synonym: yIF2
so part of: sequence
location: <76427..>79435
location: region:76427-79435:1
so has part: feature:76427-79435:1:exon
subclass of: SO_0000010

851196
type: Gene
SIO_000068: ncbigene

position:76427:1
position: 76427
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:79435:1
position: 79435
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:76427-79435:1:exon

YAL035W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: yIF2
gene: FUN12
locus tag: YAL035W
gene synonym: yIF2
product: translation initiation factor eIF5B
transcript id: NM_001178180.1
SIO_010081: YAL035W
subclass of: SO_0000673
so part of: YAL035W
location: <76427..>79435
location: region:76427-79435:1
so has part: feature:76427-79435:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:76427-79435:1:exon

YAL035W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: yIF2
gene: FUN12
locus tag: YAL035W
gene synonym: yIF2
EC number: 3.6.5.3
experiment: EXISTENCE:direct assay:GO:0001732 formation of cytoplasmic translation initiation complex [PMID:12008673]
experiment: EXISTENCE:direct assay:GO:0003743 translation initiation factor activity [PMID:12008673|PMID:9624054]
experiment: EXISTENCE:direct assay:GO:0003924 GTPase activity [PMID:19029250|PMID:16461768|PMID:17189426|PMID:12507428]
experiment: EXISTENCE:direct assay:GO:0005525 GTP binding [PMID:21335519|PMID:17189426]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0010494 cytoplasmic stress granule [PMID:26777405]
experiment: EXISTENCE:direct assay:GO:0022627 cytosolic small ribosomal subunit [PMID:9624054]
experiment: EXISTENCE:direct assay:GO:0031369 translation initiation factor binding [PMID:10982835]
experiment: EXISTENCE:direct assay:GO:0033290 eukaryotic 48S preinitiation complex [PMID:17242201]
experiment: EXISTENCE:direct assay:GO:0043022 ribosome binding [PMID:21335519|PMID:12507428]
experiment: EXISTENCE:direct assay:GO:0070181 small ribosomal subunit rRNA binding [PMID:19029250]
experiment: EXISTENCE:mutant phenotype:GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:22751017]
experiment: EXISTENCE:mutant phenotype:GO:0001732 formation of cytoplasmic translation initiation complex [PMID:17242201|PMID:12507428|PMID:17189426]
experiment: EXISTENCE:mutant phenotype:GO:0003924 GTPase activity [PMID:12471154]
experiment: EXISTENCE:mutant phenotype:GO:0006446 regulation of translational initiation [PMID:12507428]
experiment: EXISTENCE:mutant phenotype:GO:0042255 ribosome assembly [PMID:22770215]
experiment: EXISTENCE:mutant phenotype:GO:0042256 cytosolic ribosome assembly [PMID:12507428]
note: Translation initiation factor eIF5B; GTPase that promotes Met-tRNAiMet binding to ribosomes and ribosomal subunit joining; promotes GTP-dependent maturation of 18S rRNA by Nob1p; protein abundance increases in response to DNA replication stress; homolog of bacterial IF2
codon start: 1
product: translation initiation factor eIF5B
translation: MAKKSKKNQQNYWDEEFEEDAAQNEEISATPTPNPESSAGADDTSREASASAEGAEAIEGDFMSTLKQSKKKQEKKVIEEKKDGKPILKSKKEKEKEKKEKEKQKKKEQAARKKAQQQAQKEKNKELNKQNVEKAAAEKAAAEKSQKSKGESDKPSASAKKPAKKVPAGLAALRRQLELKKQLEEQEKLEREEEERLEKEEEERLANEEKMKEEAKAAKKEKEKAKREKRKAEGKLLTRKQKEEKKLLERRRAALLSSGNVKVAGLAKKDGEENKPKKVVYSKKKKRTTQENASEAIKSDSKKDSEVVPDDELKESEDVLIDDWENLALGDDDEEGTNEETQESTASHENEDQNQGEEEEEGEEEEEEEEERAHVHEVAKSTPAATPAATPTPSSASPNKKDLRSPICCILGHVDTGKTKLLDKIRQTNVQGGEAGGITQQIGATYFPIDAIKAKTKVMAEYEKQTFDVPGLLVIDTPGHESFSNLRSRGSSLCNIAILVIDIMHGLEQQTIESIKLLRDRKAPFVVALNKIDRLYDWKAIPNNSFRDSFAKQSRAVQEEFQSRYSKIQLELAEQGLNSELYFQNKNMSKYVSIVPTSAVTGEGVPDLLWLLLELTQKRMSKQLMYLSHVEATILEVKVVEGFGTTIDVILSNGYLREGDRIVLCGMNGPIVTNIRALLTPQPLRELRLKSEYVHHKEVKAALGVKIAANDLEKAVSGSRLLVVGPEDDEDELMDDVMDDLTGLLDSVDTTGKGVVVQASTLGSLEALLDFLKDMKIPVMSIGLGPVYKRDVMKASTMLEKAPEYAVMLCFDVKVDKEAEQYAEQEGIKIFNADVIYHLFDSFTAYQEKLLEERRKDFLDYAIFPCVLQTLQIINKRGPMIIGVDVLEGTLRVGTPICAVKTDPTTKERQTLILGKVISLEINHQPVQEVKKGQTAAGVAVRLEDPSGQQPIWGRHVDENDTLYSLVSRRSIDTLKDKAFRDQVARSDWLLLKKLKVVFGIE
SIO_010081: YAL035W
subclass of: SO_0000673
so part of: YAL035W
location: 76427..79435
location: region:76427-79435:1
so has part: feature:76427-79435:1:exon

NP_009365.1
type: Protein
SIO_000068: ncbiprotein

S000000033
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:76427-79435:1:exon

YAL034W-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: DSN3
alternative label: NSL2
gene: MTW1
locus tag: YAL034W-A
gene synonym: DSN3; NSL2
so part of: sequence
location: <79718..>80587
location: region:79718-80587:1
so has part: feature:79718-80587:1:exon
subclass of: SO_0000010

851197
type: Gene
SIO_000068: ncbigene

position:79718:1
position: 79718
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:80587:1
position: 80587
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:79718-80587:1:exon

YAL034W-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: DSN3
alternative label: NSL2
gene: MTW1
locus tag: YAL034W-A
gene synonym: DSN3; NSL2
product: MIND complex subunit MTW1
transcript id: NM_001178179.1
SIO_010081: YAL034W-A
subclass of: SO_0000673
so part of: YAL034W-A
location: <79718..>80587
location: region:79718-80587:1
so has part: feature:79718-80587:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:79718-80587:1:exon

YAL034W-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: DSN3
alternative label: NSL2
gene: MTW1
locus tag: YAL034W-A
gene synonym: DSN3; NSL2
experiment: EXISTENCE:direct assay:GO:0000444 MIS12/MIND type complex [PMID:14633972]
experiment: EXISTENCE:direct assay:GO:0000922 spindle pole [PMID:12455957]
experiment: EXISTENCE:direct assay:GO:0007059 chromosome segregation [PMID:12455957]
experiment: EXISTENCE:mutant phenotype:GO:0034501 protein localization to kinetochore [PMID:19893618]
note: Essential component of the MIND kinetochore complex; joins kinetochore subunits contacting DNA to those contacting microtubules; critical to kinetochore assembly; complex consists of Mtw1p Including Nnf1p-Nsl1p-Dsn1p (MIND)
codon start: 1
product: MIND complex subunit MTW1
translation: MSAPTMRSTSILTEHLGYPPISLVDDIINAVNEIMYKCTAAMEKYLLSKSKIGEEDYGEEIKSGVAKLESLLENSVDKNFDKLELYVLRNVLRIPEEYLDANVFRLENQKDLVIVDENELKKSEEKLREKVNDVELAFKKNEMLLKRVTKVKRLLFTIRGFKQKLNELLKCKDDVQLQKILESLKPIDDTMTLLTDSLRKLYVDSESTSSTEEVEALLQRLKTNGKQNNKDFRTRYIDIRTNNVLRKLGLLGDKEDEKQSAKPDARTQAGDIVSIDIEEPQLDLLDDVL
SIO_010081: YAL034W-A
subclass of: SO_0000673
so part of: YAL034W-A
location: 79718..80587
location: region:79718-80587:1
so has part: feature:79718-80587:1:exon

NP_009367.1
type: Protein
SIO_000068: ncbiprotein

S000000032
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:79718-80587:1:exon

YAL034C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FUN19
locus tag: YAL034C
so part of: sequence
location: complement(<80710..>81951)
location: region:80710-81951:-1
so has part: feature:80710-81951:-1:exon
subclass of: SO_0000010

851199
type: Gene
SIO_000068: ncbigene

position:80710:-1
position: 80710
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:81951:-1
position: 81951
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:80710-81951:-1:exon

YAL034C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FUN19
locus tag: YAL034C
product: Fun19p
transcript id: NM_001180035.1
SIO_010081: YAL034C
subclass of: SO_0000673
so part of: YAL034C
location: complement(<80710..>81951)
location: region:80710-81951:-1
so has part: feature:80710-81951:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:80710-81951:-1:exon

YAL034C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FUN19
locus tag: YAL034C
note: Non-essential hypothetical protein; expression induced in response to heat stress; FUN19 has a paralog, YOR338W, that arose from the whole genome duplication
codon start: 1
product: Fun19p
translation: MGLYSPESEKSQLNMNYIGKDDSQSIFRRLNQNLKASNNNNDSNKNGLNMSDYSNNSPYGRSYDVRINQNSQNNGNGCFSGSIDSLVDEHIIPSPPLSPKLESKISHNGSPRMASSVLVGSTPKGAVENVLFVKPVWPNGLSRKRYRYATYGFLSQYKIFSNLAQPYSKNIINRYNNLAYNARHKYSKYNDDMTPPPLPSSSSRLPSPLASPNLNRQARYNMRKQALYNNNLGKFESDTEWIPRKRKVYSPQRRTMTTSPHRAKKFSPSASTPHTNIASIEAIHDAPQYIPNVSWKKLPDYSPPLSTLPTDSNKSLKIEWKGSPMDLSTDPLRNELHPAELVLAQTLRLPCDLYLDSKRRLFLEKVYRLKKGLPFRRTDAQKACRIDVNKASRLFQAFEKVGWLQDSNFTKYL
SIO_010081: YAL034C
subclass of: SO_0000673
so part of: YAL034C
location: complement(80710..81951)
location: region:80710-81951:-1
so has part: feature:80710-81951:-1:exon

NP_009368.2
type: Protein
SIO_000068: ncbiprotein

S000002134
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:80710-81951:-1:exon

YAL033W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: FUN53
gene: POP5
locus tag: YAL033W
gene synonym: FUN53
so part of: sequence
location: <82706..>83227
location: region:82706-83227:1
so has part: feature:82706-83227:1:exon
subclass of: SO_0000010

851200
type: Gene
SIO_000068: ncbigene

position:82706:1
position: 82706
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:83227:1
position: 83227
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:82706-83227:1:exon

YAL033W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: FUN53
gene: POP5
locus tag: YAL033W
gene synonym: FUN53
product: RNA-binding protein POP5
transcript id: NM_001178178.1
SIO_010081: YAL033W
subclass of: SO_0000673
so part of: YAL033W
location: <82706..>83227
location: region:82706-83227:1
so has part: feature:82706-83227:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:82706-83227:1:exon

YAL033W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: FUN53
gene: POP5
locus tag: YAL033W
gene synonym: FUN53
EC number: 3.1.26.5
experiment: EXISTENCE:direct assay:GO:0000171 ribonuclease MRP activity [PMID:9620854]
experiment: EXISTENCE:direct assay:GO:0000172 ribonuclease MRP complex [PMID:9620854]
experiment: EXISTENCE:direct assay:GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay [PMID:14729943]
experiment: EXISTENCE:direct assay:GO:0003723 RNA binding [PMID:23700311]
experiment: EXISTENCE:direct assay:GO:0004526 ribonuclease P activity [PMID:9620854]
experiment: EXISTENCE:direct assay:GO:0005655 nucleolar ribonuclease P complex [PMID:9620854]
experiment: EXISTENCE:direct assay:GO:0034965 intronic box C/D RNA processing [PMID:18713869]
experiment: EXISTENCE:mutant phenotype:GO:0000171 ribonuclease MRP activity [PMID:9620854]
experiment: EXISTENCE:mutant phenotype:GO:0004526 ribonuclease P activity [PMID:9620854]
experiment: EXISTENCE:mutant phenotype:GO:0006364 rRNA processing [PMID:9620854]
experiment: EXISTENCE:mutant phenotype:GO:0008033 tRNA processing [PMID:9620854]
experiment: EXISTENCE:physical interaction:GO:0000172 ribonuclease MRP complex [PMID:17881380]
note: Subunit of both RNase MRP and nuclear RNase P; RNase MRP cleaves pre-rRNA, while nuclear RNase P cleaves tRNA precursors to generate mature 5' ends and facilitates turnover of nuclear RNAs
codon start: 1
product: RNA-binding protein POP5
translation: MVRLKSRYILFEIIFPPTDTNVEESVSKADILLSHHRASPADVSIKSILQEIRRSLSLNLGDYGSAKCNSLLQLKYFSNKTSTGIIRCHREDCDLVIMALMLMSKIGDVDGLIVNPVKVSGTIKKIEQFAMRRNSKILNIIKCSQSSHLSDNDFIINDFKKIGRENENENEDD
SIO_010081: YAL033W
subclass of: SO_0000673
so part of: YAL033W
location: 82706..83227
location: region:82706-83227:1
so has part: feature:82706-83227:1:exon

NP_009369.1
type: Protein
SIO_000068: ncbiprotein

S000000031
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:82706-83227:1:exon

YAL032C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: FUN20
gene: PRP45
locus tag: YAL032C
gene synonym: FUN20
so part of: sequence
location: complement(<83335..>84474)
location: region:83335-84474:-1
so has part: feature:83335-84474:-1:exon
subclass of: SO_0000010

851201
type: Gene
SIO_000068: ncbigene

position:83335:-1
position: 83335
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:84474:-1
position: 84474
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:83335-84474:-1:exon

YAL032C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: FUN20
gene: PRP45
locus tag: YAL032C
gene synonym: FUN20
product: mRNA splicing protein PRP45
transcript id: NM_001178177.1
SIO_010081: YAL032C
subclass of: SO_0000673
so part of: YAL032C
location: complement(<83335..>84474)
location: region:83335-84474:-1
so has part: feature:83335-84474:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:83335-84474:-1:exon

YAL032C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: FUN20
gene: PRP45
locus tag: YAL032C
gene synonym: FUN20
experiment: EXISTENCE:curator inference:GO:0000384 first spliceosomal transesterification activity [PMID:12554883]
experiment: EXISTENCE:curator inference:GO:0000386 second spliceosomal transesterification activity [PMID:12554883]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:12359070]
experiment: EXISTENCE:direct assay:GO:0071006 U2-type catalytic step 1 spliceosome [PMID:12554883]
experiment: EXISTENCE:direct assay:GO:0071007 U2-type catalytic step 2 spliceosome [PMID:12554883]
experiment: EXISTENCE:direct assay:GO:0071014 post-mRNA release spliceosomal complex [PMID:12554883]
experiment: EXISTENCE:genetic interaction:GO:0000350 generation of catalytic spliceosome for second transesterification step [PMID:19016306]
experiment: EXISTENCE:mutant phenotype:GO:0000350 generation of catalytic spliceosome for second transesterification step [PMID:19016306]
note: Protein required for pre-mRNA splicing; associates with the spliceosome and interacts with splicing factors Prp22p and Prp46p; orthologous to human transcriptional coactivator SKIP and can activate transcription of a reporter gene
codon start: 1
product: mRNA splicing protein PRP45
translation: MFSNRLPPPKHSQGRVSTALSSDRVEPAILTDQIAKNVKLDDFIPKRQSNFELSVPLPTKAEIQECTARTKSYIQRLVNAKLANSNNRASSRYVTETHQAPANLLLNNSHHIEVVSKQMDPLLPRFVGKKARKVVAPTENDEVVPVLHMDGSNDRGEADPNEWKIPAAVSNWKNPNGYTVALERRVGKALDNENNTINDGFMKLSEALENADKKARQEIRSKMELKRLAMEQEMLAKESKLKELSQRARYHNGTPQTGAIVKPKKQTSTVARLKELAYSQGRDVSEKIILGAAKRSEQPDLQYDSRFFTRGANASAKRHEDQVYDNPLFVQQDIESIYKTNYEKLDEAVNVKSEGASGSHGPIQFTKAESDDKSDNYGA
SIO_010081: YAL032C
subclass of: SO_0000673
so part of: YAL032C
location: complement(83335..84474)
location: region:83335-84474:-1
so has part: feature:83335-84474:-1:exon

NP_009370.1
type: Protein
SIO_000068: ncbiprotein

S000000030
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:83335-84474:-1:exon

YAL031C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: FUN21
gene: GIP4
locus tag: YAL031C
gene synonym: FUN21
so part of: sequence
location: complement(<84749..>87031)
location: region:84749-87031:-1
so has part: feature:84749-87031:-1:exon
subclass of: SO_0000010

851202
type: Gene
SIO_000068: ncbigene

position:84749:-1
position: 84749
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:87031:-1
position: 87031
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:84749-87031:-1:exon

YAL031C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: FUN21
gene: GIP4
locus tag: YAL031C
gene synonym: FUN21
product: protein phosphatase regulator GIP4
transcript id: NM_001178176.1
SIO_010081: YAL031C
subclass of: SO_0000673
so part of: YAL031C
location: complement(<84749..>87031)
location: region:84749-87031:-1
so has part: feature:84749-87031:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:84749-87031:-1:exon

YAL031C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: FUN21
gene: GIP4
locus tag: YAL031C
gene synonym: FUN21
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0008157 protein phosphatase 1 binding [PMID:16537909]
experiment: EXISTENCE:mutant phenotype:GO:0007059 chromosome segregation [PMID:16537909]
experiment: EXISTENCE:mutant phenotype:GO:0019888 protein phosphatase regulator activity [PMID:16537909]
experiment: EXISTENCE:mutant phenotype:GO:0043666 regulation of phosphoprotein phosphatase activity [PMID:16537909]
note: Cytoplasmic protein that regulates protein phosphatase 1 Glc7p; protein overexpression relocalizes Glc7p from the nucleus and prevents chromosome segregation; potential Cdc28p substrate
codon start: 1
product: protein phosphatase regulator GIP4
translation: MVDVQKRKKLLAKAAASASIPAIKGSVPLDSYDIKIIQYKNALYKLNELNRLLNVLVPHLKKKRDNDESYKIIPLVNFILSLCEGPIFNVSPVLAKRYHLLCRFQLIKLSEVQQRLSTNFIDVEGWMFPEEVPLDHYKSCIYNNSLQWKILNSLSCIAQNAIKIYNAKLRQILLERDAYKARSLPFDTSIIEDLLNPVEMTLILDLAVLINDPVRDKSTHSFYKLQWQVMEKLNSCVHSKIFPILRTYYNQLQKFSETRPTSLSNLQKDLPHWEWTLHRIYTFHLRVFSVLCVIISFSRQIFLPNKQHFLDIKTRLSSENVYHYDLIICELMALLSPECDDVTALFELQENLKFWTQTARTDNNSSRTPIFHLQPGLVVELFNNHICKIIPKLRSIMGLLSNWMDCWKYIEKNYKTFDETNDLRENLKEKLERDKALYLEVKNAKSKLKKKPSITKLPASSSPSPSPTSSASPSRQASLESIRTRARAHLASNSSRSPSVSPVRTTFNNKNAETKKSVVSPEKRKLINGRRPRSSSLQSYTNKQQTSYLNSTRHPSIAPPSKLNNQRSNSLQSSTMTLNQKIVQDTVRHLMNKSASTPNPSASSSLAPSPKVSSINNTSSGKSSSTLIANSSDTLAIETLTLDPESNSSELSIKRVRFAGVPPMTEAENPKPTKVGWYKKPAVLHYPPIPASAMIKPLQHKSKYNTLRQEEGFTFRKSLRDGLEWENGESGSETTMMPFGIEIKESTGHRIASKIRSKLR
SIO_010081: YAL031C
subclass of: SO_0000673
so part of: YAL031C
location: complement(84749..87031)
location: region:84749-87031:-1
so has part: feature:84749-87031:-1:exon

NP_009371.1
type: Protein
SIO_000068: ncbiprotein

S000000029
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:84749-87031:-1:exon

YAL030W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SNC1
locus tag: YAL030W
so part of: sequence
location: <87286..>87752
location: region:87286-87752:1
so has part: feature:87286-87752:1:exon
subclass of: SO_0000010

851203
type: Gene
SIO_000068: ncbigene

position:87286:1
position: 87286
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:87752:1
position: 87752
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:87286-87752:1:exon

YAL030W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SNC1
locus tag: YAL030W
product: SNAP receptor SNC1
transcript id: NM_001178175.1
SIO_010081: YAL030W
subclass of: SO_0000673
so part of: YAL030W
location: join(<87286..87387,87501..>87752)
location: region:87286-87752:1
so has part: feature:87286-87387:1:exon
so has part: feature:87501-87752:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:87286-87387:1:exon

position:87387:1
position: 87387
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:87501-87752:1:exon

position:87501:1
position: 87501
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YAL030W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SNC1
locus tag: YAL030W
experiment: EXISTENCE:direct assay:GO:0005484 SNAP receptor activity [PMID:14981247]
experiment: EXISTENCE:direct assay:GO:0005768 endosome [PMID:16452633]
experiment: EXISTENCE:direct assay:GO:0005802 trans-Golgi network [PMID:16452633|PMID:36125415]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:10637288|PMID:36125415]
experiment: EXISTENCE:direct assay:GO:0005933 cellular bud [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:20059749]
experiment: EXISTENCE:direct assay:GO:0006906 vesicle fusion [PMID:11001046]
experiment: EXISTENCE:direct assay:GO:0030658 transport vesicle membrane [PMID:10637288]
experiment: EXISTENCE:direct assay:GO:0031201 SNARE complex [PMID:9195974]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0006887 exocytosis [PMID:9195971]
experiment: EXISTENCE:mutant phenotype:GO:0006893 Golgi to plasma membrane transport [PMID:8374953]
experiment: EXISTENCE:mutant phenotype:GO:0006897 endocytosis [PMID:11029060]
note: Vesicle membrane receptor protein (v-SNARE); involved in the fusion between Golgi-derived secretory vesicles with the plasma membrane; proposed to be involved in endocytosis; member of the synaptobrevin/VAMP family of R-type v-SNARE proteins; SNC1 has a paralog, SNC2, that arose from the whole genome duplication
codon start: 1
product: SNAP receptor SNC1
translation: MSSSTPFDPYALSEHDEERPQNVQSKSRTAELQAEIDDTVGIMRDNINKVAERGERLTSIEDKADNLAVSAQGFKRGANRVRKAMWYKDLKMKMCLALVIIILLVVIIVPIAVHFSR
SIO_010081: YAL030W
subclass of: SO_0000673
so part of: YAL030W
location: join(87286..87387,87501..87752)
location: region:87286-87752:1
so has part: feature:87286-87387:1:exon
so has part: feature:87501-87752:1:exon

NP_009372.1
type: Protein
SIO_000068: ncbiprotein

S000000028
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:87286-87387:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:87501-87752:1:exon

YAL029C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: FUN22
alternative label: SHE1
gene: MYO4
locus tag: YAL029C
gene synonym: FUN22; SHE1
so part of: sequence
location: complement(<87855..>92270)
location: region:87855-92270:-1
so has part: feature:87855-92270:-1:exon
subclass of: SO_0000010

851204
type: Gene
SIO_000068: ncbigene

position:87855:-1
position: 87855
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:92270:-1
position: 92270
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:87855-92270:-1:exon

YAL029C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: FUN22
alternative label: SHE1
gene: MYO4
locus tag: YAL029C
gene synonym: FUN22; SHE1
product: myosin 4
transcript id: NM_001178174.1
SIO_010081: YAL029C
subclass of: SO_0000673
so part of: YAL029C
location: complement(<87855..>92270)
location: region:87855-92270:-1
so has part: feature:87855-92270:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:87855-92270:-1:exon

YAL029C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: FUN22
alternative label: SHE1
gene: MYO4
locus tag: YAL029C
gene synonym: FUN22; SHE1
experiment: EXISTENCE:direct assay:GO:0000146 microfilament motor activity [PMID:11381095]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961|PMID:14576278]
experiment: EXISTENCE:direct assay:GO:0005933 cellular bud [PMID:12725728|PMID:20439999]
experiment: EXISTENCE:direct assay:GO:0005934 cellular bud tip [PMID:20439999]
experiment: EXISTENCE:direct assay:GO:0031941 filamentous actin [PMID:11381095]
experiment: EXISTENCE:direct assay:GO:0051015 actin filament binding [PMID:11381095]
experiment: EXISTENCE:mutant phenotype:GO:0007533 mating type switching [PMID:8625407]
experiment: EXISTENCE:mutant phenotype:GO:0008298 intracellular mRNA localization [PMID:11030653|PMID:9219698|PMID:9288973]
experiment: EXISTENCE:mutant phenotype:GO:0048309 endoplasmic reticulum inheritance [PMID:14691136|PMID:16890529]
experiment: EXISTENCE:physical interaction:GO:0008298 intracellular mRNA localization [PMID:10212145|PMID:11030653]
note: Type V myosin motor involved in actin-based transport of cargos; required for mRNA transport, including ASH1 mRNA, and facilitating the growth and movement of ER tubules into the growing bud along with She3p; MYO4 has a paralog, MYO2, that arose from the whole genome duplication
codon start: 1
product: myosin 4
translation: MSFEVGTKCWYPHKEQGWIGGEVTKNDFFEGTFHLELKLEDGETVSIETNSFENDDDHPTLPVLRNPPILESTDDLTTLSYLNEPAVLHAIKKRYMNGQIYTYSGIVLIAANPFDKVDHLYSREMIQNYSSKRKDELEPHLFAIAEEAYRFMVHEKANQTVVVSGESGAGKTVSAKYIMRYFASVQESNNREGEVEMSQIESQILATNPIMEAFGNAKTTRNDNSSRFGKYLQILFDENTTIRGSKIRTYLLEKSRLVYQPETERNYHIFYQILEGLPEPVKQELHLSSPKDYHYTNQGGQPNIAGIDEAREYKITTDALSLVGINHETQLGIFKILAGLLHIGNIEMKMTRNDASLSSEEQNLQIACELLGIDPFNFAKWIVKKQIVTRSEKIVTNLNYNQALIARDSVAKFIYSTLFDWLVDNINKTLYDPELDQQDHVFSFIGILDIYGFEHFEKNSFEQFCINYANEKLQQEFNQHVFKLEQEEYVKEEIEWSFIEFSDNQPCIDLIENKLGILSLLDEESRLPSGSDESWASKLYSAFNKPPSNEVFSKPRFGQTKFIVSHYAVDVEYEVEGFIEKNRDSVSLGHLDVFKATTNPIFKQILDNRELRSDDAPEEQNTEKKIMIPARLSQKKPTLGSMFKKSLGELMAIINSTNVHYIRCIKPNSEKKPWEFDNLMVLSQLRACGVLETIRISCAGFPSRWTFDEFVQRYFLLTDYSLWSGILYNPDLPKEAIVNFCQSILDATISDSAKYQIGNTKIFFKAGMLAFLEKLRTNKMNEICIIIQKKIRARYYRLQYLQTMESIKKCQSQIRSLLVRTRVDHELKTRAAILLQTNIRALWKREYYRAAIGQIIKLQCTCKRKLILDSVNRKFMLMAAVIIQSYIRSYGHKTDYRTLKRSSILVQSAMRMQLARRRYIVLQKEVEERNIRASYGIGLLEEAIEFKNSFILNLEMLNDSYTRLTQLLQGDLSNIPSKQRQEYETIVNGYNDKISKLKTLQVEIMNTLNKKNALKERKKKQSSLIQSHMQSLAAIKGNKPSRLSDEVKSMKQELAFIENVIAQDFTTTYSANKNDKVKGLGIAGQQVKPKLVNVIRRESGNPDLLELLMDLNCYTLEVTEGYLKKVNVTEVNGDNVLGPIHVITTVVSSLVRNGLLIQSSKFISKVLLTVESIVMSLPKDETMLGGIFWLSNLSRLPAFAANQKTLYEANGGDEKDKLTLIYLNDLENETLKVFDKIYSTWLVKFMKHASAHIEIFDMVLNEKLFKNSGDEKFAKLFTFLNEFDAVLCKFQVVDSMHTKIFNDTLKYLNVMLFNDLITKCPALNWKYGYEVDRNIERLVSWFEPRIEDVRPNLIQIIQAVKILQLKISNLNEFKLLFDFWYALNPAQIQAILLKYKPANKGEAGVPNEILNYLANVIKRENLSLPGKMEIMLSAQFDSAKNHLRYDTSAITQNSNTEGLATVSKIIKLDRK
SIO_010081: YAL029C
subclass of: SO_0000673
so part of: YAL029C
location: complement(87855..92270)
location: region:87855-92270:-1
so has part: feature:87855-92270:-1:exon

NP_009373.1
type: Protein
SIO_000068: ncbiprotein

S000000027
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:87855-92270:-1:exon

YAL028W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: HPH2
gene: FRT2
locus tag: YAL028W
gene synonym: HPH2
so part of: sequence
location: <92900..>94486
location: region:92900-94486:1
so has part: feature:92900-94486:1:exon
subclass of: SO_0000010

851205
type: Gene
SIO_000068: ncbigene

position:92900:1
position: 92900
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:94486:1
position: 94486
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:92900-94486:1:exon

YAL028W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: HPH2
gene: FRT2
locus tag: YAL028W
gene synonym: HPH2
product: Frt2p
transcript id: NM_001178173.1
SIO_010081: YAL028W
subclass of: SO_0000673
so part of: YAL028W
location: <92900..>94486
location: region:92900-94486:1
so has part: feature:92900-94486:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:92900-94486:1:exon

YAL028W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: HPH2
gene: FRT2
locus tag: YAL028W
gene synonym: HPH2
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:15189990]
experiment: EXISTENCE:mutant phenotype:GO:0071469 cellular response to alkaline pH [PMID:15189990]
experiment: EXISTENCE:mutant phenotype:GO:0071472 cellular response to salt stress [PMID:15189990]
experiment: EXISTENCE:physical interaction:GO:0031204 post-translational protein targeting to membrane, translocation [PMID:21097665]
note: Tail-anchored ER membrane hypothetical protein; interacts with homolog Frt1p; promotes growth in conditions of high Na+, alkaline pH, or cell wall stress, possibly via a role in posttranslational translocation; potential Cdc28p substrate; FRT2 has a paralog, FRT1, that arose from the whole genome duplication
codon start: 1
product: Frt2p
translation: MQNAQIKSSSKGSGIDGTDRNSKDGVEKRPLEDVKQMIDAGTPDVGHKSTVETKPNVGWQASHSNLAALHEKEQKYEMEHHHARHKLHRQVIPDYTSASTAMFSDCMFNAAPDKVRSLSTMKSSGLSPKHPFNVVATFKGPFPQHSVESKPLDGGYSAKDHFPSFKMLQAQQHPAHRHYKDNDKYGLKSPSRSFVKDKKRLVHRFLKSMEPSSSGQSKDSSALAPAFDPILPNVISKPSKRPTHHSHSSDGSSSTQTDISLQSLLYHDLESSPKKHVSPSRPPSVASESSPAVANPIGLSPKDACNASFSQSSSSSLSSSSSSSSSTSFSQSVAVDPLEPPGNITYSSSNLSLNSDELDYYQRHIGLQLQQTEALLKHSLKDEVLKDENDLVKNIANFDKIVKELRDLRSRTIGWKELVEEDYLMNLKQDFDKENPESFEARLSDTINTNVAKLQDLEKRMASCKDRLASRKEVMRKMESLLSLENSLMISKKNVTFASKYRNEALDIVFLIIIIVICYTFKHLVSHK
SIO_010081: YAL028W
subclass of: SO_0000673
so part of: YAL028W
location: 92900..94486
location: region:92900-94486:1
so has part: feature:92900-94486:1:exon

NP_009374.1
type: Protein
SIO_000068: ncbiprotein

S000000026
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:92900-94486:1:exon

YAL027W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SAW1
locus tag: YAL027W
so part of: sequence
location: <94687..>95472
location: region:94687-95472:1
so has part: feature:94687-95472:1:exon
subclass of: SO_0000010

851206
type: Gene
SIO_000068: ncbigene

position:94687:1
position: 94687
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:95472:1
position: 95472
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:94687-95472:1:exon

YAL027W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SAW1
locus tag: YAL027W
product: DNA-binding protein SAW1
transcript id: NM_001178172.1
SIO_010081: YAL027W
subclass of: SO_0000673
so part of: YAL027W
location: <94687..>95472
location: region:94687-95472:1
so has part: feature:94687-95472:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:94687-95472:1:exon

YAL027W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SAW1
locus tag: YAL027W
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0032079 positive regulation of endodeoxyribonuclease activity [PMID:23299942]
experiment: EXISTENCE:direct assay:GO:0070337 3'-flap-structured DNA binding [PMID:23299942]
experiment: EXISTENCE:direct assay:GO:0070338 5'-flap-structured DNA binding [PMID:23299942]
experiment: EXISTENCE:genetic interaction:GO:0000736 double-strand break repair via single-strand annealing, removal of nonhomologous ends [PMID:18471978]
experiment: EXISTENCE:mutant phenotype:GO:0000736 double-strand break repair via single-strand annealing, removal of nonhomologous ends [PMID:18471978]
note: 5'- and 3'-flap DNA binding protein; required for recruitment of Rad1p-Rad10p to single-strand annealing intermediates with 3' non-homologous tails for removal during double-strand break repair; forms a complex with Rad1p-Rad10p and stimulates its endonuclease activity; green fluorescent protein (GFP)-fusion protein localizes to the nucleus
codon start: 1
product: DNA-binding protein SAW1
translation: MAPSIATVKIARDMVLPLRIFVNRKQILQTNDKTSNKSNATIFEAPLLSNNSIICLKSPNTRIYLSQQDKKNLCDEIKEDLLLIVYELASPEIISSVLSKIRVGHSTDFQINVLPKLFAGADTDNAVTSHIQSVTRLAKFKYKLHYKHKWELDIFINSIKKIANLRHYLMFQTLTLNGFSLNAGPKTLLARKIEKQPQVPNLLIENGDADALDTPVEEDIKPVIEFMYKPVINLGEIIDVHVLHRPRRHKVRTQSKQPQEE
SIO_010081: YAL027W
subclass of: SO_0000673
so part of: YAL027W
location: 94687..95472
location: region:94687-95472:1
so has part: feature:94687-95472:1:exon

NP_009375.1
type: Protein
SIO_000068: ncbiprotein

S000000025
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:94687-95472:1:exon

YAL026C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: FUN38
alternative label: SWA3
gene: DRS2
locus tag: YAL026C
gene synonym: FUN38; SWA3
so part of: sequence
location: complement(<95630..>99697)
location: region:95630-99697:-1
so has part: feature:95630-99697:-1:exon
subclass of: SO_0000010

851207
type: Gene
SIO_000068: ncbigene

position:95630:-1
position: 95630
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:99697:-1
position: 99697
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:95630-99697:-1:exon

YAL026C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: FUN38
alternative label: SWA3
gene: DRS2
locus tag: YAL026C
gene synonym: FUN38; SWA3
product: aminophospholipid-translocating P4-type ATPase DRS2
transcript id: NM_001178171.2
SIO_010081: YAL026C
subclass of: SO_0000673
so part of: YAL026C
location: complement(<95630..>99697)
location: region:95630-99697:-1
so has part: feature:95630-99697:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:95630-99697:-1:exon

YAL026C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: FUN38
alternative label: SWA3
gene: DRS2
locus tag: YAL026C
gene synonym: FUN38; SWA3
EC number: 7.6.2.1
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005802 trans-Golgi network [PMID:12221123|PMID:15090616|PMID:10601336]
experiment: EXISTENCE:genetic interaction:GO:0000749 response to pheromone triggering conjugation with cellular fusion [PMID:25378585]
experiment: EXISTENCE:genetic interaction:GO:0006886 intracellular protein transport [PMID:12221123]
experiment: EXISTENCE:genetic interaction:GO:0006892 post-Golgi vesicle-mediated transport [PMID:10601336]
experiment: EXISTENCE:genetic interaction:GO:0006897 endocytosis [PMID:12631737|PMID:16195350]
experiment: EXISTENCE:genetic interaction:GO:0090555 phosphatidylethanolamine flippase activity [PMID:16452632]
experiment: EXISTENCE:genetic interaction:GO:0140345 phosphatidylcholine flippase activity [PMID:16452632]
experiment: EXISTENCE:genetic interaction:GO:0140346 phosphatidylserine flippase activity [PMID:16452632]
experiment: EXISTENCE:mutant phenotype:GO:0006892 post-Golgi vesicle-mediated transport [PMID:10601336]
experiment: EXISTENCE:mutant phenotype:GO:0032456 endocytic recycling [PMID:24272750]
experiment: EXISTENCE:mutant phenotype:GO:0045332 phospholipid translocation [PMID:15249668|PMID:16452632]
experiment: EXISTENCE:mutant phenotype:GO:0090555 phosphatidylethanolamine flippase activity [PMID:16452632]
experiment: EXISTENCE:mutant phenotype:GO:0140346 phosphatidylserine flippase activity [PMID:8633245|PMID:15249668|PMID:16452632]
experiment: EXISTENCE:physical interaction:GO:1990530 Cdc50p-Drs2p complex [PMID:15090616]
note: Trans-golgi network aminophospholipid translocase (flippase); P4-type ATPase; maintains membrane lipid asymmetry in post-Golgi secretory vesicles; contributes to clathrin-coated vesicle formation, endocytosis, protein trafficking between the Golgi and endosomal system and the cellular response to mating pheromone; autoinhibited by its C-terminal tail; localizes to the trans-Golgi network
codon start: 1
product: aminophospholipid-translocating P4-type ATPase DRS2
translation: MNDDRETPPKRKPGEDDTLFDIDFLDDTTSHSGSRSKVTNSHANANYIPPSHVLPEETIDLDADDDNIENDVHENLFMSNNHDDQTSWNANRFDSDAYQPQSLRAVKPPGLFARFGNGLKNAFTFKRKKGPESFEMNHYNAVTNNELDDNYLDSRNKFNIKILFNRYILRKNVGDAEGNGEPRVIHINDSLANSSFGYSDNHISTTKYNFATFLPKFLFQEFSKYANLFFLCTSAIQQVPHVSPTNRYTTIGTLLVVLIVSAMKECIEDIKRANSDKELNNSTAEIFSEAHDDFVEKRWIDIRVGDIIRVKSEEPIPADTIILSSSEPEGLCYIETANLDGETNLKIKQSRVETAKFIDVKTLKNMNGKVVSEQPNSSLYTYEGTMTLNDRQIPLSPDQMILRGATLRNTAWIFGLVIFTGHETKLLRNATATPIKRTAVEKIINRQIIALFTVLIVLILISSIGNVIMSTADAKHLSYLYLEGTNKAGLFFKDFLTFWILFSNLVPISLFVTVELIKYYQAFMIGSDLDLYYEKTDTPTVVRTSSLVEELGQIEYIFSDKTGTLTRNIMEFKSCSIAGHCYIDKIPEDKTATVEDGIEVGYRKFDDLKKKLNDPSDEDSPIINDFLTLLATCHTVIPEFQSDGSIKYQAASPDEGALVQGGADLGYKFIIRKPNSVTVLLEETGEEKEYQLLNICEFNSTRKRMSAIFRFPDGSIKLFCKGADTVILERLDDEANQYVEATMRHLEDYASEGLRTLCLAMRDISEGEYEEWNSIYNEAATTLDNRAEKLDEAANLIEKNLILIGATAIEDKLQDGVPETIHTLQEAGIKIWVLTGDRQETAINIGMSCRLLSEDMNLLIINEETRDDTERNLLEKINALNEHQLSTHDMNTLALVIDGKSLGFALEPELEDYLLTVAKLCKAVICCRVSPLQKALVVKMVKRKSSSLLLAIGDGANDVSMIQAAHVGVGISGMEGMQAARSADIAVGQFKFLKKLLLVHGSWSYQRISVAILYSFYKNTALYMTQFWYVFANAFSGQSIMESWTMSFYNLFFTVWPPFVIGVFDQFVSSRLLERYPQLYKLGQKGQFFSVYIFWGWIINGFFHSAIVFIGTILIYRYGFALNMHGELADHWSWGVTVYTTSVIIVLGKAALVTNQWTKFTLIAIPGSLLFWLIFFPIYASIFPHANISREYYGVVKHTYGSGVFWLTLIVLPIFALVRDFLWKYYKRMYEPETYHVIQEMQKYNISDSRPHVQQFQNAIRKVRQVQRMKKQRGFAFSQAEEGGQEKIVRMYDTTQKRGKYGELQDASANPFNDNNGLGSNDFESAEPFIENPFADGNQNSNRFSSSRDDISFDI
SIO_010081: YAL026C
subclass of: SO_0000673
so part of: YAL026C
location: complement(95630..99697)
location: region:95630-99697:-1
so has part: feature:95630-99697:-1:exon

NP_009376.2
type: Protein
SIO_000068: ncbiprotein

S000000024
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:95630-99697:-1:exon

YNCA0001W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: HRA1
locus tag: YNCA0001W
so part of: sequence
location: 99305..99868
location: region:99305-99868:1
so has part: feature:99305-99868:1:exon
subclass of: SO_0000011

9164866
type: Gene
SIO_000068: ncbigene

position:99305:1
position: 99305
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:99868:1
position: 99868
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:99305-99868:1:exon

YNCA0001W
type: Non Coding RNA
subclass of: SO_0000655
RO_0002162: 559292
nc RNA class: other
gene: HRA1
locus tag: YNCA0001W
product: HRA1
note: Non-protein-coding RNA; substrate of RNase P, possibly involved in rRNA processing, specifically maturation of 20S precursor into the mature 18S rRNA
transcript id: NR_132149.1
SIO_010081: YNCA0001W
subclass of: SO_0000673
so part of: YNCA0001W
location: 99305..99868
location: region:99305-99868:1
so has part: feature:99305-99868:1:exon

S000119380
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:99305-99868:1:exon

YAL025C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MAK16
locus tag: YAL025C
so part of: sequence
location: complement(<100225..>101145)
location: region:100225-101145:-1
so has part: feature:100225-101145:-1:exon
subclass of: SO_0000010

851208
type: Gene
SIO_000068: ncbigene

position:100225:-1
position: 100225
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:101145:-1
position: 101145
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:100225-101145:-1:exon

YAL025C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MAK16
locus tag: YAL025C
product: ribosome biosynthesis protein MAK16
transcript id: NM_001178170.2
SIO_010081: YAL025C
subclass of: SO_0000673
so part of: YAL025C
location: complement(<100225..>101145)
location: region:100225-101145:-1
so has part: feature:100225-101145:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:100225-101145:-1:exon

YAL025C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MAK16
locus tag: YAL025C
experiment: EXISTENCE:direct assay:GO:0005730 nucleolus [PMID:10838225]
experiment: EXISTENCE:direct assay:GO:0030687 preribosome, large subunit precursor [PMID:11583614]
experiment: EXISTENCE:mutant phenotype:GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:16710831]
experiment: EXISTENCE:mutant phenotype:GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [PMID:16710831]
experiment: EXISTENCE:mutant phenotype:GO:0042273 ribosomal large subunit biogenesis [PMID:7739558]
note: Essential nuclear protein; constituent of 66S pre-ribosomal particles; required for maturation of 25S and 5.8S rRNAs; required for maintenance of M1 satellite double-stranded RNA of the L-A virus
codon start: 1
product: ribosome biosynthesis protein MAK16
translation: MSDEIVWQVINQSFCSHRIKAPNGQNFCRNEYNVTGLCTRQSCPLANSKYATVKCDNGKLYLYMKTPERAHTPAKLWERIKLSKNYTKALQQIDEHLLHWSKFFRHKCKQRFTKLTQVMITERRLALREEERHYVGVAPKVKRREQNRERKALVAAKIEKAIEKELMDRLKSGAYGDKPLNVDEKVWKKIMGQMEEENSQDEEEDWDEEEESDDGEVEYVADDGEGEYVDVDDLEKWLADSDREASSASESESDSESESDSDSDEENKNSAKRRKKGTSAKTKRPKVEIEYEEEHEVQNAEQEVAQ
SIO_010081: YAL025C
subclass of: SO_0000673
so part of: YAL025C
location: complement(100225..101145)
location: region:100225-101145:-1
so has part: feature:100225-101145:-1:exon

NP_009377.2
type: Protein
SIO_000068: ncbiprotein

S000000023
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:100225-101145:-1:exon

YAL024C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MSI2
gene: LTE1
locus tag: YAL024C
gene synonym: MSI2
so part of: sequence
location: complement(<101565..>105872)
location: region:101565-105872:-1
so has part: feature:101565-105872:-1:exon
subclass of: SO_0000010

851209
type: Gene
SIO_000068: ncbigene

position:101565:-1
position: 101565
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:105872:-1
position: 105872
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:101565-105872:-1:exon

YAL024C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MSI2
gene: LTE1
locus tag: YAL024C
gene synonym: MSI2
product: mitotic regulator LTE1
transcript id: NM_001178169.1
SIO_010081: YAL024C
subclass of: SO_0000673
so part of: YAL024C
location: complement(<101565..>105872)
location: region:101565-105872:-1
so has part: feature:101565-105872:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:101565-105872:-1:exon

YAL024C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MSI2
gene: LTE1
locus tag: YAL024C
gene synonym: MSI2
experiment: EXISTENCE:direct assay:GO:0005933 cellular bud [PMID:12782684]
experiment: EXISTENCE:genetic interaction:GO:0016192 vesicle-mediated transport [PMID:17121813]
experiment: EXISTENCE:mutant phenotype:GO:0031536 positive regulation of exit from mitosis [PMID:27798238]
experiment: EXISTENCE:mutant phenotype:GO:0061510 asymmetric protein localization to new mitotic spindle pole body [PMID:19948498]
note: Protein similar to GDP/GTP exchange factors; without detectable GEF activity; required for asymmetric localization of Bfa1p at daughter-directed spindle pole bodies and for mitotic exit at low temperatures
codon start: 1
product: mitotic regulator LTE1
translation: MEIFSQKDYYPTPSSNVISYESDCVSKPVNSADLPALIVHLSSPLEGVDYNASADFFLIYRNFITPQDLHDLLIYRFRWCIREITTNAAKAKRRRIGEVALVRTFVLLRHSILNYFVQDFLPNITLRLRLIEFLNDKHIEQYPKIISSCIINLKKNWVHCSKLVWENIELNEPDKLDFDAWLHYSLKDFTQLESLHKRGSRLSIYARQSFASPDFRNQSVLSLYKTSDVFRLPEKLQSSNSSKNQRSPSMLLFPDNTSNVYSKHRIAKEPSVDNESEDMSDSKQKISHLSKVTLVSTLMKGVDYPSSYAVDKIMPPTPAKKVEFILNSLYIPEDLNEQSGTLQGTSTTSSLDNNSNSNSRSNTSSMSVLHRSAIGLLAKWMKNHNRHDSSNDKKFMSAIKPANQKPEMDAFVKYVVSISSLNRKSSKEEEEEFLNSDSSKFDILSARTIDEVESLLHLQNQLIEKVQTHSNNNRGPTVNVDCERREHIHDIKILQQNSFKPSNDNFSAMDNLDLYQTVSSIAQSVISLTNTLNKQLQNNESNMQPSPSYDALQRRKVKSLTTAYYNKMHGSYSAESMRLFDKDNSSSRTDENGPQRLLFHETDKTNSEAITNMTPRRKNHSQSQKSMTSSPLKNVLPDLKESSPLNDSREDTESITYSYDSELSSSSPPRDTVTKKSRKVRNIVNNTDSPTLKTKTGFLNLREFTFEDTKSLDEKKSTIDGLEKNYDNKENQESEYESTKKLDNSLDASSEANNYDITTRKKHSSCNHKIKQAVVRPASGRISISRVQSIAITPTKELSIVDPEQNKSNSVIEEISEIEPLNLEYNKKSALYSDTSSTVISISTSKLFESAQNSPLKQTQNPQREFPNGTSVSETNRIRLSIAPTIESVVSDLNSITTGSTVETFETSRDLPVPHQRIINLREEYQRGNQDIISNTSSLHELKTIDLSDSNNDLESPSTHAKNNKYFFSPDDGSIDVASPMKNVEELKSKFLKNESETNSNISGSVLTMDDIDINDTSSARNTRRANSESAFTGSLNKKNLNEIANMLDDSINDDPITVALMKLEGTYEKIPEKPENTKSSDAIGIKTSKLADEVEMLNLNNLPSFQNSPAEKRKSLLIERRRQTIMNIPFTPDQSEKEGFTSSSPEKIDVSANVDVAVQAAQIQELIGQYRIHDSRLMISNNESHVPFILMYDSLSVAQQMTLIEKEILGEIDWKDLLDLKMKHEGPQVISWLQLLVRNETLSGIDLAISRFNLTVDWIISEILLTKSSKMKRNVIQRFIHVADHCRTFQNFNTLMEIILALSSSVVQKFTDAWRLIEPGDLLTWEELKKIPSLDRNYSTIRNLLNSVNPLVGCVPFIVVYLSDLSANAEKKDWILEDKVVNYNKFDTNVQIVKNFIQRVQWSKFYTFKVNHELLSKCVYISTLTQEEINELST
SIO_010081: YAL024C
subclass of: SO_0000673
so part of: YAL024C
location: complement(101565..105872)
location: region:101565-105872:-1
so has part: feature:101565-105872:-1:exon

NP_009378.1
type: Protein
SIO_000068: ncbiprotein

S000000022
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:101565-105872:-1:exon

YAL023C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: FUN25
gene: PMT2
locus tag: YAL023C
gene synonym: FUN25
so part of: sequence
location: complement(<106272..>108551)
location: region:106272-108551:-1
so has part: feature:106272-108551:-1:exon
subclass of: SO_0000010

851210
type: Gene
SIO_000068: ncbigene

position:106272:-1
position: 106272
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:108551:-1
position: 108551
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:106272-108551:-1:exon

YAL023C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: FUN25
gene: PMT2
locus tag: YAL023C
gene synonym: FUN25
product: dolichyl-phosphate-mannose-protein mannosyltransferase PMT2
transcript id: NM_001178168.1
SIO_010081: YAL023C
subclass of: SO_0000673
so part of: YAL023C
location: complement(<106272..>108551)
location: region:106272-108551:-1
so has part: feature:106272-108551:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:106272-108551:-1:exon

YAL023C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: FUN25
gene: PMT2
locus tag: YAL023C
gene synonym: FUN25
EC number: 2.4.1.109
experiment: EXISTENCE:direct assay:GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity [PMID:21956107]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0097582 dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt2p dimer complex [PMID:12551906]
experiment: EXISTENCE:direct assay:GO:0097584 dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt2p dimer complex [PMID:12551906]
experiment: EXISTENCE:genetic interaction:GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity [PMID:21956107|PMID:7852348|PMID:8543034]
experiment: EXISTENCE:genetic interaction:GO:0032527 protein exit from endoplasmic reticulum [PMID:21147851]
experiment: EXISTENCE:genetic interaction:GO:0035269 protein O-linked mannosylation [PMID:21231968|PMID:7852348|PMID:8543034]
experiment: EXISTENCE:genetic interaction:GO:0071712 ER-associated misfolded protein catabolic process [PMID:21147851]
experiment: EXISTENCE:genetic interaction:GO:1900101 regulation of endoplasmic reticulum unfolded protein response [PMID:21231968|PMID:23704572]
experiment: EXISTENCE:mutant phenotype:GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity [PMID:7852348|PMID:8543034]
experiment: EXISTENCE:mutant phenotype:GO:0006493 protein O-linked glycosylation [PMID:9184828]
experiment: EXISTENCE:mutant phenotype:GO:0035269 protein O-linked mannosylation [PMID:7852348|PMID:8543034|PMID:18182384]
experiment: EXISTENCE:mutant phenotype:GO:0071712 ER-associated misfolded protein catabolic process [PMID:18182384]
experiment: EXISTENCE:mutant phenotype:GO:1900101 regulation of endoplasmic reticulum unfolded protein response [PMID:23704572]
experiment: EXISTENCE:physical interaction:GO:0097582 dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt2p dimer complex [PMID:21956107|PMID:8543034]
note: Protein O-mannosyltransferase of the ER membrane; transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; involved in ER quality control; functions as a heterodimer with Pmt2p but can also pair with Pmt5p; antifungal drug target; PMT2 has a paralog, PMT3, that arose from the whole genome duplication
codon start: 1
product: dolichyl-phosphate-mannose-protein mannosyltransferase PMT2
translation: MSSSSSTGYSKNNAAHIKQENTLRQRESSSISVSEELSSADERDAEDFSKEKPAAQSSLLRLESVVMPVIFTALALFTRMYKIGINNHVVWDEAHFGKFGSYYLRHEFYHDVHPPLGKMLVGLSGYLAGYNGSWDFPSGEIYPDYLDYVKMRLFNASFSALCVPLAYFTAKAIGFSLPTVWLMTVLVLFENSYSTLGRFILLDSMLLFFTVASFFSFVMFHNQRSKPFSRKWWKWLLITGISLGCTISVKMVGLFIITMVGIYTVIDLWTFLADKSMSWKTYINHWLARIFGLIIVPFCIFLLCFKIHFDLLSHSGTGDANMPSLFQARLVGSDVGQGPRDIALGSSVVSIKNQALGGSLLHSHIQTYPDGSNQQQVTCYGYKDANNEWFFNRERGLPSWSENETDIEYLKPGTSYRLVHKSTGRNLHTHPVAAPVSKTQWEVSGYGDNVVGDNKDNWVIEIMDQRGDEDPEKLHTLTTSFRIKNLEMGCYLAQTGNSLPEWGFRQQEVVCMKNPFKRDKRTWWNIETHENERLPPRPEDFQYPKTNFLKDFIHLNLAMMATNNALVPDPDKFDYLASSAWQWPTLNVGLRLCGWGDDNPKYFLLGTPASTWASSVAVLAFMATVVILLIRWQRQYVDLRNPSNWNVFLMGGFYPLLAWGLHYMPFVIMSRVTYVHHYLPALYFALIILAYCFDAGLQKWSRSKCGRIMRFVLYAGFMALVIGCFWYFSPISFGMEGPSSNFRYLNWFSTWDIADKQEA
SIO_010081: YAL023C
subclass of: SO_0000673
so part of: YAL023C
location: complement(106272..108551)
location: region:106272-108551:-1
so has part: feature:106272-108551:-1:exon

NP_009379.2
type: Protein
SIO_000068: ncbiprotein

S000000021
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:106272-108551:-1:exon

YAL022C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FUN26
locus tag: YAL022C
so part of: sequence
location: complement(<108877..>110430)
location: region:108877-110430:-1
so has part: feature:108877-110430:-1:exon
subclass of: SO_0000010

851211
type: Gene
SIO_000068: ncbigene

position:108877:-1
position: 108877
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:110430:-1
position: 110430
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:108877-110430:-1:exon

YAL022C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FUN26
locus tag: YAL022C
product: nucleoside transmembrane transporter FUN26
transcript id: NM_001178167.1
SIO_010081: YAL022C
subclass of: SO_0000673
so part of: YAL022C
location: complement(<108877..>110430)
location: region:108877-110430:-1
so has part: feature:108877-110430:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:108877-110430:-1:exon

YAL022C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FUN26
locus tag: YAL022C
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:21349851|PMID:19001347|PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005337 nucleoside transmembrane transporter activity [PMID:10827169|PMID:25035431]
experiment: EXISTENCE:direct assay:GO:0015205 nucleobase transmembrane transporter activity [PMID:25035431]
experiment: EXISTENCE:direct assay:GO:0015851 nucleobase transport [PMID:25035431]
experiment: EXISTENCE:direct assay:GO:0015858 nucleoside transport [PMID:10827169|PMID:25035431]
experiment: EXISTENCE:direct assay:GO:0055085 transmembrane transport [PMID:10827169]
experiment: EXISTENCE:mutant phenotype:GO:0034257 nicotinamide riboside transmembrane transporter activity [PMID:21349851]
experiment: EXISTENCE:mutant phenotype:GO:0034258 nicotinamide riboside transport [PMID:21349851]
note: High affinity, broad selectivity, nucleoside/nucleobase transporter; vacuolar membrane localized transporter which may regulate the balance of nicotinamide riboside (NmR) levels between the cytosol and vacuole, contributing to salvage of NmR for use in cytosolic NAD+ synthesis; equilibrative nucleoside transporter (ENT) family member
codon start: 1
product: nucleoside transmembrane transporter FUN26
translation: MSTSADTDTIKKPILAVPEPALADTHSEEISRSGEEHESENNEHSDEEGDNYSEREQSVSTEPLDTLPLRKKLKNLSYITFFAIGIGLLWPWNCILSASQYFKHDIFKDTSIWAKIFTSSMMSFSTISSMLFNIYLAKRQYKYSRRVINGLVWEIIVFTVMCFFTILHFLLPKWFNFMFIMMLVVISSMGTAMTQNGIMAIANVFGSEYSQGVMVGQAVAGVLPSLVLFALAFIENSSVSTTGGILLYFFTTTLVVTICVVMFSVSKISRKVNENWNVEDGHITDVLLGSLRSNEEEIRIVGRIDQMEDEDHRRTNGTRDDNDEGEELQLKVPFEVLFAKLKYLVLSIFTTFVVTLVFPVFASATYVTGLPLSNAQYIPLIFTLWNLGDLYGRVIADWPMFRDQKFTPRKTFIYSLLRVAAIPLFLMFTAITSSSSGDEEHNGSVIVDLCYMLLQFLFGVTNGHVISMSFMKVPEQLDNDDEKEAAGGFTNIFVSTGLALGSIISYVFVFIIDFIIR
SIO_010081: YAL022C
subclass of: SO_0000673
so part of: YAL022C
location: complement(108877..110430)
location: region:108877-110430:-1
so has part: feature:108877-110430:-1:exon

NP_009380.1
type: Protein
SIO_000068: ncbiprotein

S000000020
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:108877-110430:-1:exon

YAL021C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: FUN27
alternative label: NUT21
gene: CCR4
locus tag: YAL021C
gene synonym: FUN27; NUT21
so part of: sequence
location: complement(<110846..>113359)
location: region:110846-113359:-1
so has part: feature:110846-113359:-1:exon
subclass of: SO_0000010

851212
type: Gene
SIO_000068: ncbigene

position:110846:-1
position: 110846
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:113359:-1
position: 113359
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:110846-113359:-1:exon

YAL021C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: FUN27
alternative label: NUT21
gene: CCR4
locus tag: YAL021C
gene synonym: FUN27; NUT21
product: CCR4-NOT core exoribonuclease subunit CCR4
transcript id: NM_001178166.1
SIO_010081: YAL021C
subclass of: SO_0000673
so part of: YAL021C
location: complement(<110846..>113359)
location: region:110846-113359:-1
so has part: feature:110846-113359:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:110846-113359:-1:exon

YAL021C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: FUN27
alternative label: NUT21
gene: CCR4
locus tag: YAL021C
gene synonym: FUN27; NUT21
EC number: 3.1.13.4
experiment: EXISTENCE:direct assay:GO:0000175 3'-5'-exoribonuclease activity [PMID:11889048]
experiment: EXISTENCE:direct assay:GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [PMID:11889048]
experiment: EXISTENCE:direct assay:GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening [PMID:11889048]
experiment: EXISTENCE:direct assay:GO:0000932 P-body [PMID:18611963]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:11889048]
experiment: EXISTENCE:direct assay:GO:0030015 CCR4-NOT core complex [PMID:10490603]
experiment: EXISTENCE:direct assay:GO:0032968 positive regulation of transcription elongation by RNA polymerase II [PMID:21406554]
experiment: EXISTENCE:genetic interaction:GO:0000076 DNA replication checkpoint signaling [PMID:17158920]
experiment: EXISTENCE:genetic interaction:GO:0000175 3'-5'-exoribonuclease activity [PMID:11889048]
experiment: EXISTENCE:genetic interaction:GO:0006260 DNA replication [PMID:17158920]
experiment: EXISTENCE:genetic interaction:GO:0006368 transcription elongation by RNA polymerase II promoter [PMID:11404327]
experiment: EXISTENCE:genetic interaction:GO:0048478 replication fork protection [PMID:17158920]
experiment: EXISTENCE:mutant phenotype:GO:0000175 3'-5'-exoribonuclease activity [PMID:11239395|PMID:11889048]
experiment: EXISTENCE:mutant phenotype:GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [PMID:11889048]
experiment: EXISTENCE:mutant phenotype:GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening [PMID:11410650|PMID:17158920]
experiment: EXISTENCE:mutant phenotype:GO:0006368 transcription elongation by RNA polymerase II promoter [PMID:11404327]
experiment: EXISTENCE:mutant phenotype:GO:0007089 traversing start control point of mitotic cell cycle [PMID:15075273]
experiment: EXISTENCE:physical interaction:GO:0006357 regulation of transcription by RNA polymerase II [PMID:10490603]
experiment: EXISTENCE:physical interaction:GO:0016593 Cdc73/Paf1 complex [PMID:9891041]
note: Component of the CCR4-NOT transcriptional complex; CCR4-NOT is involved in regulation of gene expression; component of the major cytoplasmic deadenylase, which is involved in mRNA poly(A) tail shortening
codon start: 1
product: CCR4-NOT core exoribonuclease subunit CCR4
translation: MNDPSLLGYPNVGPQQQQQQQQQQHAGLLGKGTPNALQQQLHMNQLTGIPPPGLMNNSDVHTSSNNNSRQLLDQLANGNANMLNMNMDNNNNNNNNNNNNNNNGGGSGVMMNASTAAVNSIGMVPTVGTPVNINVNASNPLLHPHLDDPSLLNNPIWKLQLHLAAVSAQSLGQPNIYARQNAMKKYLATQQAQQAQQQAQQQAQQQVPGPFGPGPQAAPPALQPTDFQQSHIAEASKSLVDCTKQALMEMADTLTDSKTAKKQQPTGDSTPSGTATNSAVSTPLTPKIELFANGKDEANQALLQHKKLSQYSIDEDDDIENRMVMPKDSKYDDQLWHALDLSNLQIFNISANIFKYDFLTRLYLNGNSLTELPAEIKNLSNLRVLDLSHNRLTSLPAELGSCFQLKYFYFFDNMVTTLPWEFGNLCNLQFLGVEGNPLEKQFLKILTEKSVTGLIFYLRDNRPEIPLPHERRFIEINTDGEPQREYDSLQQSTEHLATDLAKRTFTVLSYNTLCQHYATPKMYRYTPSWALSWDYRRNKLKEQILSYDSDLLCLQEVESKTFEEYWVPLLDKHGYTGIFHAKARAKTMHSKDSKKVDGCCIFFKRDQFKLITKDAMDFSGAWMKHKKFQRTEDYLNRAMNKDNVALFLKLQHIPSGDTIWAVTTHLHWDPKFNDVKTFQVGVLLDHLETLLKEETSHNFRQDIKKFPVLICGDFNSYINSAVYELINTGRVQIHQEGNGRDFGYMSEKNFSHNLALKSSYNCIGELPFTNFTPSFTDVIDYIWFSTHALRVRGLLGEVDPEYVSKFIGFPNDKFPSDHIPLLARFEFMKTNTGSKKV
SIO_010081: YAL021C
subclass of: SO_0000673
so part of: YAL021C
location: complement(110846..113359)
location: region:110846-113359:-1
so has part: feature:110846-113359:-1:exon

NP_009381.1
type: Protein
SIO_000068: ncbiprotein

S000000019
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:110846-113359:-1:exon

YAL020C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: FUN28
alternative label: KTI13
gene: ATS1
locus tag: YAL020C
gene synonym: FUN28; KTI13
so part of: sequence
location: complement(<113614..>114615)
location: region:113614-114615:-1
so has part: feature:113614-114615:-1:exon
subclass of: SO_0000010

851213
type: Gene
SIO_000068: ncbigene

position:113614:-1
position: 113614
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:114615:-1
position: 114615
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:113614-114615:-1:exon

YAL020C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: FUN28
alternative label: KTI13
gene: ATS1
locus tag: YAL020C
gene synonym: FUN28; KTI13
product: Ats1p
transcript id: NM_001178165.2
SIO_010081: YAL020C
subclass of: SO_0000673
so part of: YAL020C
location: complement(<113614..>114615)
location: region:113614-114615:-1
so has part: feature:113614-114615:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:113614-114615:-1:exon

YAL020C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: FUN28
alternative label: KTI13
gene: ATS1
locus tag: YAL020C
gene synonym: FUN28; KTI13
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:18466297]
experiment: EXISTENCE:mutant phenotype:GO:0002098 tRNA wobble uridine modification [PMID:18755837]
note: Protein required for modification of wobble nucleosides in tRNA; acts with Elongator complex, Kti11p, and Kti12p; has a potential role in regulatory interactions between microtubules and the cell cycle; forms a stable heterodimer with Kti11p
codon start: 1
product: Ats1p
translation: MSCVYAFGSNGQRQLGLGHDEDMDTPQRSVPGDDGAIVRKIACGGNHSVMLTNDGNLVGCGDNRRGELDSAQALRQVHDWRPVEVPAPVVDVACGWDTTVIVDADGRVWQRGGGCYEFTQQHVPLNSNDERIAVYGCFQNFVVVQGTRVYGWGSNTKCQLQEPKSRSLKEPVLVYDTGSVAVDYVAMGKDFMVIVDEGGRIVHASGRLPTGFELKQQQKRHNLVVLCMWTSIHLWNARLNTVESFGRGTHSQLFPQERLDFPIVGVATGSEHGILTTANQEGKSHCYNVYCWGWGEHGNCGPQKGSQPGLQLVGQYSGKPRVFGGCATTWIVL
SIO_010081: YAL020C
subclass of: SO_0000673
so part of: YAL020C
location: complement(113614..114615)
location: region:113614-114615:-1
so has part: feature:113614-114615:-1:exon

NP_009382.2
type: Protein
SIO_000068: ncbiprotein

S000000018
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:113614-114615:-1:exon

YAL019W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: FUN30
locus tag: YAL019W
so part of: sequence
location: <114919..>118314
location: region:114919-118314:1
so has part: feature:114919-118314:1:exon
subclass of: SO_0000010

851214
type: Gene
SIO_000068: ncbigene

position:114919:1
position: 114919
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:118314:1
position: 118314
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:114919-118314:1:exon

YAL019W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: FUN30
locus tag: YAL019W
product: DNA-dependent ATPase FUN30
transcript id: NM_001178164.1
SIO_010081: YAL019W
subclass of: SO_0000673
so part of: YAL019W
location: <114919..>118314
location: region:114919-118314:1
so has part: feature:114919-118314:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:114919-118314:1:exon

YAL019W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: FUN30
locus tag: YAL019W
EC number: 3.6.4.12
experiment: EXISTENCE:direct assay:GO:0000775 chromosome, centromeric region [PMID:23028372]
experiment: EXISTENCE:direct assay:GO:0003677 DNA binding [PMID:20075079]
experiment: EXISTENCE:direct assay:GO:0003682 chromatin binding [PMID:20075079]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095|PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0031934 mating-type region heterochromatin [PMID:19956593]
experiment: EXISTENCE:direct assay:GO:0140658 ATP-dependent chromatin remodeler activity [PMID:20075079|PMID:23779104]
experiment: EXISTENCE:mutant phenotype:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:23779104]
experiment: EXISTENCE:mutant phenotype:GO:0000183 rDNA heterochromatin formation [PMID:19956593]
experiment: EXISTENCE:mutant phenotype:GO:0000729 DNA double-strand break processing [PMID:22960743|PMID:22960744]
experiment: EXISTENCE:mutant phenotype:GO:0006338 chromatin remodeling [PMID:23779104|PMID:33141948|PMID:20075079]
experiment: EXISTENCE:mutant phenotype:GO:0030466 silent mating-type cassette heterochromatin formation [PMID:19956593]
experiment: EXISTENCE:mutant phenotype:GO:0031507 heterochromatin formation [PMID:21388962]
experiment: EXISTENCE:mutant phenotype:GO:0031509 subtelomeric heterochromatin formation [PMID:19956593]
experiment: EXISTENCE:mutant phenotype:GO:0033120 positive regulation of RNA splicing [PMID:32234239]
experiment: EXISTENCE:mutant phenotype:GO:0140658 ATP-dependent chromatin remodeler activity [PMID:19956593]
note: Snf2p family member with ATP-dependent chromatin remodeling activity; has a role in silencing at the mating type locus, telomeres and centromeres; enriched at centromeres and is required for correct chromatin structure around centromeres, as well as at the boundary element of the silent HMR; recruited to DNA double-strand breaks (DSBs) where it promotes 5' strand resection of DSBs; potential Cdc28p substrate
codon start: 1
product: DNA-dependent ATPase FUN30
translation: MSGSHSNDEDDVVQVPETSSPTKVASSSPLKPTSPTVPDASVASLRSRFTFKPSDPSEGAHTSKPLPSGSPEVALVNLAREFPDFSQTLVQAVFKSNSFNLQSARERLTRLRQQRQNWTWNKNASPKKSETPPPVKKSLPLANTGRLSSIHGNINNKSSKITVAKQKTSIFDRYSNVINQKQYTFELPTNLNIDSEALSKLPVNYNKKRRLVRADQHPIGKSYESSATQLGSAREKLLANRKYGRHANDNDEEEEESMMTDDDDASGDDYTESTPQINLDEQVLQFINDSDIVDLSDLSDTTMHKAQLIASHRPYSSLNAFVNTNFNDKDTEENASNKRKRRAAASANESERLLDKITQSIRGYNAIESVIKKCSSYGDLVTSQMKKWGVQVEGDNSELDLMNLGEDDDDDNDDGNNDNNNSNNNNTAGADATSKEKEDTKAVVEGFDETSAEPTPAPAPAPVERETKRIRNTTKPKVVEDEDDDVDLEAIDDELPQSEHEDDDYEEEDEDYNDEEEDVEYDDGDDDDDDDDEFVATRKNTHVISTTSRNGRKPIVKFFKGKPRLLSPEISLKDYQQTGINWLNLLYQNKMSCILADDMGLGKTCQVISFFAYLKQINEPGPHLVVVPSSTLENWLREFQKFAPALKIEPYYGSLQEREELRDILERNAGKYDVIVTTYNLAAGNKYDVSFLKNRNFNVVVYDEGHMLKNSTSERFAKLMKIRANFRLLLTGTPLQNNLKELMSLLEFIMPNLFISKKESFDAIFKQRAKTTDDNKNHNPLLAQEAITRAKTMMKPFILRRRKDQVLKHLPPKHTHIQYCELNAIQKKIYDKEIQIVLEHKRMIKDGELPKDAKEKSKLQSSSSKNLIMALRKASLHPLLFRNIYNDKIITKMSDAILDEPAYAENGNKEYIKEDMSYMTDFELHKLCCNFPNTLSKYQLHNDEWMQSGKIDALKKLLKTIIVDKQEKVLIFSLFTQVLDILEMVLSTLDYKFLRLDGSTQVNDRQLLIDKFYEDKDIPIFILSTKAGGFGINLVCANNVIIFDQSFNPHDDRQAADRAHRVGQTKEVNITTLITKDSIEEKIHQLAKNKLALDSYISEDKKSQDVLESKVSDMLEDIIYDENSKPKGTKE
SIO_010081: YAL019W
subclass of: SO_0000673
so part of: YAL019W
location: 114919..118314
location: region:114919-118314:1
so has part: feature:114919-118314:1:exon

NP_009383.1
type: Protein
SIO_000068: ncbiprotein

S000000017
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:114919-118314:1:exon

YAL018C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: LDS1
locus tag: YAL018C
so part of: sequence
location: complement(<118564..>119541)
location: region:118564-119541:-1
so has part: feature:118564-119541:-1:exon
subclass of: SO_0000010

851215
type: Gene
SIO_000068: ncbigene

position:118564:-1
position: 118564
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:119541:-1
position: 119541
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:118564-119541:-1:exon

YAL018C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: LDS1
locus tag: YAL018C
product: Lds1p
transcript id: NM_001178163.1
SIO_010081: YAL018C
subclass of: SO_0000673
so part of: YAL018C
location: complement(<118564..>119541)
location: region:118564-119541:-1
so has part: feature:118564-119541:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:118564-119541:-1:exon

YAL018C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: LDS1
locus tag: YAL018C
experiment: EXISTENCE:direct assay:GO:0005619 ascospore wall [PMID:23966878]
experiment: EXISTENCE:direct assay:GO:0005628 prospore membrane [PMID:23966878]
experiment: EXISTENCE:direct assay:GO:0005811 lipid droplet [PMID:24390141]
experiment: EXISTENCE:genetic interaction:GO:0030476 ascospore wall assembly [PMID:23966878]
note: Protein Involved in spore wall assembly; localizes to lipid droplets found on or outside of the prospore membrane; shares similarity with Lds2p and Rrt8p, and a strain mutant for all 3 genes exhibits reduced dityrosine fluorescence relative to the single mutants
codon start: 1
product: Lds1p
translation: MSFTGSLALAGIGGLVYKFGGGQSYEKLPYVNIPFNQYLDKVYKKHFSKVMSRTRYVLMNFFKDAFTGGAFMYPFKGFLEFNTNKSSYSTTMLGILSSYLIMFALVSFVYWATITPMYTAFLIVLGPIGLFIAIFHSFLQANVFTLLFMRLSHFNNHLVEVCLEKNGLEENLSEVKPIKYYAPINSIYFWAYYFPFKLVKYMLGLSVLFVLLVISFFPLIGPILFHILISPFITQIYFTKVLRLQNFDNIQRRENIYLHAGQYASFGFLAGLIESVPILAGFAISTNTIGSVLFNLDHPMVPENLVETQAEIEAAPQDINQQPNQ
SIO_010081: YAL018C
subclass of: SO_0000673
so part of: YAL018C
location: complement(118564..119541)
location: region:118564-119541:-1
so has part: feature:118564-119541:-1:exon

NP_009384.1
type: Protein
SIO_000068: ncbiprotein

S000000016
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:118564-119541:-1:exon

YAL017W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: FUN31
gene: PSK1
locus tag: YAL017W
gene synonym: FUN31
so part of: sequence
location: <120225..>124295
location: region:120225-124295:1
so has part: feature:120225-124295:1:exon
subclass of: SO_0000010

851216
type: Gene
SIO_000068: ncbigene

position:120225:1
position: 120225
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:124295:1
position: 124295
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:120225-124295:1:exon

YAL017W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: FUN31
gene: PSK1
locus tag: YAL017W
gene synonym: FUN31
product: serine/threonine protein kinase PSK1
transcript id: NM_001178162.2
SIO_010081: YAL017W
subclass of: SO_0000673
so part of: YAL017W
location: <120225..>124295
location: region:120225-124295:1
so has part: feature:120225-124295:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:120225-124295:1:exon

YAL017W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: FUN31
gene: PSK1
locus tag: YAL017W
gene synonym: FUN31
EC number: 2.7.11.1
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:16319894]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22289182|PMID:14562095]
experiment: EXISTENCE:genetic interaction:GO:0060917 regulation of (1->6)-beta-D-glucan biosynthetic process [PMID:17531808]
experiment: EXISTENCE:mutant phenotype:GO:0004674 protein serine/threonine kinase activity [PMID:12372297]
experiment: EXISTENCE:mutant phenotype:GO:0045719 negative regulation of glycogen biosynthetic process [PMID:12372297]
note: PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication
codon start: 1
product: serine/threonine protein kinase PSK1
translation: MPYIGASNLSEHSFVNLKEKHAITHKGTSSSVASLQTPPSPDQENHIDNELENYDTSLSDVSTPNKKEGDEFEQSLRDTFASFRKTKPPPPLDFEQPRLPSTASSSVDSTVSSPLTDEDIKELEFLPNESTHSYSYNPLSPNSLAVRLRILKRSLEIIIQNPSMLLEPTPDDLPPLKEFAGRRSSLPRTSASANHLMNRNKSQIWNTTSATLNAFVNNTSSSSAASSALSNKKPGTPVFPNLDPTHSQTFHRANSLAYLPSILPEQDPLLKHNNSLFRGDYGNNISPERPSFRQPFKDQTSNLRNSSLLNERAYQEDETFLPHHGPSMDLLNEQRANLKSLLNLLNETLEKNTSERASDLHMISLFNLNKLMLGDPKKNNSERDKRTEKLKKILLDSLAEPFFEHYNFIGDNPIADTDELKEEIDEFTGSGDTTAITDIRPQQDYGRILRTFTSTKNSAPQAIFTCSQEDPWQFRAANDLACLVFGISQNAIRALTLMDLIHTDSRNFVLHKLLSTEGQEMVFTGEIIGIVQPETLSSSKVVWASFWAKRKNGLLVCVFEKVPCDYVDVLLNLDDFGAENIVDKCELLSDGPTLSSSSTLSLPKMASSPTGSKLEYSLERKILEKSYTKPTSTENRNGDENQLDGDSHSEPSLSSSPVRSKKSVKFANDIKDVKSISQSLAKLMDDVRNGVVFDPDDDLLPMPIKVCNHINETRYFTLNHLSYNIPCAVSSTVLEDELKLKIHSLPYQAGLFIVDSHTLDIVSSNKSILKNMFGYHFAELVGKSITEIIPSFPKFLQFINDKYPALDITLHKNKGLVLTEHFFRKIQAEIMGDRKSFYTSVGIDGLHRDGCEIKIDFQLRVMNSKVILLWVTHSRDVVFEEYNTNPSQLKMLKESELSLMSSASSSASSSKKSSSRISTGTLKDMSNLSTYEDLAHRTNKLKYEIGDDSRAHSQSTLSEQEQVPLENDKDSGEMMLADPEMKHKLELARIYSRDKSQFVKEGNFKVDENLIISKISLSPSTESLADSKSSGKGLSPLEEEKLIDENATENGLAGSPKDEDGIIMTNKRGNQPVSTFLRTPEKNIGAQKHVKKFSDFVSLQKMGEGAYGKVNLCIHKKNRYIVVIKMIFKERILVDTWVRDRKLGTIPSEIQIMATLNKKPHENILRLLDFFEDDDYYYIETPVHGETGCIDLFDLIEFKTNMTEFEAKLIFKQVVAGIKHLHDQGIVHRDIKDENVIVDSKGFVKIIDFGSAAYVKSGPFDVFVGTIDYAAPEVLGGNPYEGQPQDIWAIGILLYTVVFKENPFYNIDEILEGDLKFNNAEEVSEDCIELIKSILNRCVPKRPTIDDINNDKWLVI
SIO_010081: YAL017W
subclass of: SO_0000673
so part of: YAL017W
location: 120225..124295
location: region:120225-124295:1
so has part: feature:120225-124295:1:exon

NP_009385.2
type: Protein
SIO_000068: ncbiprotein

S000000015
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:120225-124295:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS107; Autonomously Replicating Sequence
so part of: sequence
location: 124349..124597
location: region:124349-124597:1
so has part: feature:124349-124597:1:region

S000118319
type: SGD
SIO_000068: sgd

position:124349:1
position: 124349
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:124597:1
position: 124597
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:124349-124597:1:region

YAL016W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: FUN32
gene: TPD3
locus tag: YAL016W
gene synonym: FUN32
so part of: sequence
location: <124879..>126786
location: region:124879-126786:1
so has part: feature:124879-126786:1:exon
subclass of: SO_0000010

851217
type: Gene
SIO_000068: ncbigene

position:124879:1
position: 124879
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:126786:1
position: 126786
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:124879-126786:1:exon

YAL016W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: FUN32
gene: TPD3
locus tag: YAL016W
gene synonym: FUN32
product: protein phosphatase 2A structural subunit TPD3
transcript id: NM_001178161.1
SIO_010081: YAL016W
subclass of: SO_0000673
so part of: YAL016W
location: <124879..>126786
location: region:124879-126786:1
so has part: feature:124879-126786:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:124879-126786:1:exon

YAL016W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: FUN32
gene: TPD3
locus tag: YAL016W
gene synonym: FUN32
experiment: EXISTENCE:direct assay:GO:0000159 protein phosphatase type 2A complex [PMID:17550305|PMID:8600023]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:12388751]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:12388751]
experiment: EXISTENCE:direct assay:GO:0005816 spindle pole body [PMID:12388751]
experiment: EXISTENCE:direct assay:GO:0005934 cellular bud tip [PMID:12388751]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:12388751]
experiment: EXISTENCE:direct assay:GO:0043332 mating projection tip [PMID:12388751]
experiment: EXISTENCE:mutant phenotype:GO:0004722 protein serine/threonine phosphatase activity [PMID:17550305]
experiment: EXISTENCE:mutant phenotype:GO:0006417 regulation of translation [PMID:10329624]
experiment: EXISTENCE:mutant phenotype:GO:0007094 mitotic spindle assembly checkpoint signaling [PMID:9001215]
note: Regulatory subunit A of the heterotrimeric PP2A complex; the heterotrimeric protein phosphatase 2A (PP2A) complex also contains regulatory subunit Cdc55p and either catalytic subunit Pph21p or Pph22p; required for cell morphogenesis and transcription by RNA polymerase III
codon start: 1
product: protein phosphatase 2A structural subunit TPD3
translation: MSGARSTTAGAVPSAATTSTTSTTSNSKDSDSNESLYPLALLMDELKHDDIANRVEAMKKLDTIALALGPERTRNELIPFLTEVAQDDEDEVFAVLAEQLGKFVPYIGGPQYATILLPVLEILASAEETLVREKAVDSLNNVAQELSQEQLFSDFVPLIEHLATADWFSSKVSACGLFKSVIVRIKDDSLRKNILALYLQLAQDDTPMVKRAVGKNLPILIDLLTQNLGLSTDEDWDYISNIFQKIINDNQDSVKFLAVDCLISILKFFNAKGDESHTQDLLNSAVKLIGDEAWRVRYMAADRFSDLASQFSSNQAYIDELVQPFLNLCEDNEGDVREAVAKQVSGFAKFLNDPSIILNKILPAVQNLSMDESETVRSALASKITNIVLLLNKDQVINNFLPILLNMLRDEFPDVRLNIIASLKVVNDVIGIELLSDSLLPAITELAKDVNWRVRMAIIEYIPILAEQLGMQFFDQQLSDLCLSWLWDTVYSIREAAVNNLKRLTEIFGSDWCRDEIISRLLKFDLQLLENFVSRFTILSALTTLVPVVSLDVVTEQLLPFISHLADDGVPNIRFNVAKSYAVIVKVLIKDEAKYDALIKNTILPSLQTLCQDEDVDVKYFAKKSLAECQELLKN
SIO_010081: YAL016W
subclass of: SO_0000673
so part of: YAL016W
location: 124879..126786
location: region:124879-126786:1
so has part: feature:124879-126786:1:exon

NP_009386.1
type: Protein
SIO_000068: ncbiprotein

S000000014
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:124879-126786:1:exon

YAL015C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: FUN33
alternative label: ogg2
alternative label: SCR1
gene: NTG1
locus tag: YAL015C
gene synonym: FUN33; ogg2; SCR1
so part of: sequence
location: complement(<126903..>128102)
location: region:126903-128102:-1
so has part: feature:126903-128102:-1:exon
subclass of: SO_0000010

851218
type: Gene
SIO_000068: ncbigene

position:126903:-1
position: 126903
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:128102:-1
position: 128102
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:126903-128102:-1:exon

YAL015C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: FUN33
alternative label: ogg2
alternative label: SCR1
gene: NTG1
locus tag: YAL015C
gene synonym: FUN33; ogg2; SCR1
product: bifunctional N-glycosylase/AP lyase NTG1
transcript id: NM_001178160.1
SIO_010081: YAL015C
subclass of: SO_0000673
so part of: YAL015C
location: complement(<126903..>128102)
location: region:126903-128102:-1
so has part: feature:126903-128102:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:126903-128102:-1:exon

YAL015C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: FUN33
alternative label: ogg2
alternative label: SCR1
gene: NTG1
locus tag: YAL015C
gene synonym: FUN33; ogg2; SCR1
EC number: 4.2.99.18
experiment: EXISTENCE:direct assay:GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity [PMID:9020769]
experiment: EXISTENCE:direct assay:GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity [PMID:14500818]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:10207101|PMID:19029246|PMID:24034606]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:10207101|PMID:19029246|PMID:14576278|PMID:16823961|P MID:24034606]
experiment: EXISTENCE:direct assay:GO:0006281 DNA repair [PMID:8855249]
experiment: EXISTENCE:direct assay:GO:0006284 base-excision repair [PMID:14500818]
experiment: EXISTENCE:direct assay:GO:0006285 base-excision repair, AP site formation [PMID:9826748]
experiment: EXISTENCE:direct assay:GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity [PMID:8855249]
experiment: EXISTENCE:mutant phenotype:GO:0034599 cellular response to oxidative stress [PMID:19074198]
experiment: EXISTENCE:mutant phenotype:GO:0090297 positive regulation of mitochondrial DNA replication [PMID:17116696|PMID:19074198]
note: DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase; involved in base excision repair; acts in both nucleus and mitochondrion; creates a double-strand break at mtDNA origins that stimulates replication in response to oxidative stress; required for maintaining mitochondrial genome integrity; NTG1 has a paralog, NTG2, that arose from the whole genome duplication
codon start: 1
product: bifunctional N-glycosylase/AP lyase NTG1
translation: MQKISKYSSMAILRKRPLVKTETGPESELLPEKRTKIKQEEVVPQPVDIDWVKSLPNKQYFEWIVVRNGNVPNRWATPLDPSILVTPASTKVPYKFQETYARMRVLRSKILAPVDIIGGSSIPVTVASKCGISKEQISPRDYRLQVLLGVMLSSQTKDEVTAMAMLNIMRYCIDELHSEEGMTLEAVLQINETKLDELIHSVGFHTRKAKYILSTCKILQDQFSSDVPATINELLGLPGVGPKMAYLTLQKAWGKIEGICVDVHVDRLTKLWKWVDAQKCKTPDQTRTQLQNWLPKGLWTEINGLLVGFGQIITKSRNLGDMLQFLPPDDPRSSLDWDLQSQLYKEIQQNIMSYPKWVKYLEGKRELNVEAEINVKHEEKTVEETMVKLENDISVKVED
SIO_010081: YAL015C
subclass of: SO_0000673
so part of: YAL015C
location: complement(126903..128102)
location: region:126903-128102:-1
so has part: feature:126903-128102:-1:exon

NP_009387.1
type: Protein
SIO_000068: ncbiprotein

S000000013
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:126903-128102:-1:exon

YAL014C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SLT2
alternative label: UIP2
gene: SYN8
locus tag: YAL014C
gene synonym: SLT2; UIP2
so part of: sequence
location: complement(<128252..>129019)
location: region:128252-129019:-1
so has part: feature:128252-129019:-1:exon
subclass of: SO_0000010

851219
type: Gene
SIO_000068: ncbigene

position:128252:-1
position: 128252
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:129019:-1
position: 129019
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:128252-129019:-1:exon

YAL014C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SLT2
alternative label: UIP2
gene: SYN8
locus tag: YAL014C
gene synonym: SLT2; UIP2
product: syntaxin
transcript id: NM_001178159.1
SIO_010081: YAL014C
subclass of: SO_0000673
so part of: YAL014C
location: complement(<128252..>129019)
location: region:128252-129019:-1
so has part: feature:128252-129019:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:128252-129019:-1:exon

YAL014C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SLT2
alternative label: UIP2
gene: SYN8
locus tag: YAL014C
gene synonym: SLT2; UIP2
experiment: EXISTENCE:direct assay:GO:0005484 SNAP receptor activity [PMID:12453154]
experiment: EXISTENCE:direct assay:GO:0005768 endosome [PMID:12453154]
experiment: EXISTENCE:mutant phenotype:GO:0006896 Golgi to vacuole transport [PMID:12453154]
experiment: EXISTENCE:physical interaction:GO:0006896 Golgi to vacuole transport [PMID:12453154]
note: Endosomal SNARE related to mammalian syntaxin 8
codon start: 1
product: syntaxin
translation: MDVLKLGYELDQLSDLVEERTRLVSVLKLAPTSNDNVTLKRQLGSILELLQKCAPNDELISRYNTILDKIPDTAVDKELYRFQQQVARNTDEVSKESLKKVRFKNDDELTVMYKDDDEQDEESPLPSTHTPYKDEPLQSQLQSQSQPQPPQPMVSNQELFINQQQQLLEQDSHLGALSQSIGRTHDISLDLNNEIVSQNDSLLVDLENLIDNNGRNLNRASRSMHGFNNSRFKDNGNCVIILVLIVVLLLLLLVL
SIO_010081: YAL014C
subclass of: SO_0000673
so part of: YAL014C
location: complement(128252..129019)
location: region:128252-129019:-1
so has part: feature:128252-129019:-1:exon

NP_009388.2
type: Protein
SIO_000068: ncbiprotein

S000000012
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:128252-129019:-1:exon

YAL013W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: FUN54
gene: DEP1
locus tag: YAL013W
gene synonym: FUN54
so part of: sequence
location: <129270..>130487
location: region:129270-130487:1
so has part: feature:129270-130487:1:exon
subclass of: SO_0000010

851220
type: Gene
SIO_000068: ncbigene

position:129270:1
position: 129270
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:130487:1
position: 130487
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:129270-130487:1:exon

YAL013W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: FUN54
gene: DEP1
locus tag: YAL013W
gene synonym: FUN54
product: Rpd3L histone deacetylase complex subunit DEP1
transcript id: NM_001178158.2
SIO_010081: YAL013W
subclass of: SO_0000673
so part of: YAL013W
location: <129270..>130487
location: region:129270-130487:1
so has part: feature:129270-130487:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:129270-130487:1:exon

YAL013W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: FUN54
gene: DEP1
locus tag: YAL013W
gene synonym: FUN54
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:36283334]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:36283334]
experiment: EXISTENCE:direct assay:GO:0033698 Rpd3L complex [PMID:16286007|PMID:16286008|PMID:16314178|PMID:19040720]
experiment: EXISTENCE:direct assay:GO:0070210 Rpd3L-Expanded complex [PMID:19040720]
experiment: EXISTENCE:mutant phenotype:GO:0000122 negative regulation of transcription by RNA polymerase II [PMID:16314178|PMID:24358376|PMID:8056324]
experiment: EXISTENCE:mutant phenotype:GO:0006357 regulation of transcription by RNA polymerase II [PMID:21646424|PMID:8056324]
experiment: EXISTENCE:mutant phenotype:GO:0030174 regulation of DNA-templated DNA replication initiation [PMID:19417103]
experiment: EXISTENCE:mutant phenotype:GO:0045944 positive regulation of transcription by RNA polymerase II [PMID:20398213|PMID:8056324]
experiment: EXISTENCE:mutant phenotype:GO:0061186 negative regulation of silent mating-type cassette heterochromatin formation [PMID:16286008]
experiment: EXISTENCE:mutant phenotype:GO:0061188 negative regulation of rDNA heterochromatin formation [PMID:16286008]
note: Component of the Rpd3L histone deacetylase complex; required for diauxic shift-induced histone H2B deposition onto rDNA genes; transcriptional modulator involved in regulation of structural phospholipid biosynthesis genes and metabolically unrelated genes, as well as maintenance of telomeres, mating efficiency, and sporulation; localizes to both the nucleus and mitochondria where it may play a role in mitophagy
codon start: 1
product: Rpd3L histone deacetylase complex subunit DEP1
translation: MSQQTPQESEQTTAKEQDLDQESVLSNIDFNTDLNHNLNLSEYCISSDAGTEKMDSDEEKSLANLPELKYAPKLSSLVKQETLTESLKRPHEDEKEAIDEAKKMKVPGENEDESKEEEKSQELEEAIDSKEKSTDARDEQGDEGDNEEENNEEDNENENEHTAPPALVMPSPIEMEEQRMTALKEITDIEYKFAQLRQKLYDNQLVRLQTELQMCLEGSHPELQVYYSKIAAIRDYKLHRAYQRQKYELSCINTETIATRTFIHQDFHKKVTDLRARLLNRTTQTWYDINKERRDMDIVIPDVNYHVPIKLDNKTLSCITGYASAAQLCYPGEPVAEDLACESIEYRYRANPVDKLEVIVDRMRLNNEISDLEGLRKYFHSFPGAPELNPLRDSEINDDFHQWAQ
SIO_010081: YAL013W
subclass of: SO_0000673
so part of: YAL013W
location: 129270..130487
location: region:129270-130487:1
so has part: feature:129270-130487:1:exon

NP_009389.3
type: Protein
SIO_000068: ncbiprotein

S000000011
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:129270-130487:1:exon

YAL012W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CYI1
alternative label: FUN35
alternative label: STR1
gene: CYS3
locus tag: YAL012W
gene synonym: CYI1; FUN35; STR1
so part of: sequence
location: <130799..>131983
location: region:130799-131983:1
so has part: feature:130799-131983:1:exon
subclass of: SO_0000010

851221
type: Gene
SIO_000068: ncbigene

position:130799:1
position: 130799
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:131983:1
position: 131983
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:130799-131983:1:exon

YAL012W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CYI1
alternative label: FUN35
alternative label: STR1
gene: CYS3
locus tag: YAL012W
gene synonym: CYI1; FUN35; STR1
product: cystathionine gamma-lyase CYS3
transcript id: NM_001178157.1
SIO_010081: YAL012W
subclass of: SO_0000673
so part of: YAL012W
location: <130799..>131983
location: region:130799-131983:1
so has part: feature:130799-131983:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:130799-131983:1:exon

YAL012W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CYI1
alternative label: FUN35
alternative label: STR1
gene: CYS3
locus tag: YAL012W
gene synonym: CYI1; FUN35; STR1
EC number: 4.4.1.1
experiment: EXISTENCE:direct assay:GO:0004123 cystathionine gamma-lyase activity [PMID:1577698]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095|PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0047804 cysteine-S-conjugate beta-lyase activity [PMID:29436228]
experiment: EXISTENCE:direct assay:GO:1904828 positive regulation of hydrogen sulfide biosynthetic process [PMID:31582588]
experiment: EXISTENCE:mutant phenotype:GO:0004123 cystathionine gamma-lyase activity [PMID:10509018|PMID:8366024]
experiment: EXISTENCE:mutant phenotype:GO:0019343 cysteine biosynthetic process via cystathionine [PMID:10509018]
experiment: EXISTENCE:mutant phenotype:GO:0019344 cysteine biosynthetic process [PMID:8366024]
experiment: EXISTENCE:mutant phenotype:GO:0019346 transsulfuration [PMID:8366024]
note: Cystathionine gamma-lyase; catalyzes one of the two reactions involved in the transsulfuration pathway that yields cysteine from homocysteine with the intermediary formation of cystathionine; protein abundance increases in response to DNA replication stress
codon start: 1
product: cystathionine gamma-lyase CYS3
translation: MTLQESDKFATKAIHAGEHVDVHGSVIEPISLSTTFKQSSPANPIGTYEYSRSQNPNRENLERAVAALENAQYGLAFSSGSATTATILQSLPQGSHAVSIGDVYGGTHRYFTKVANAHGVETSFTNDLLNDLPQLIKENTKLVWIETPTNPTLKVTDIQKVADLIKKHAAGQDVILVVDNTFLSPYISNPLNFGADIVVHSATKYINGHSDVVLGVLATNNKPLYERLQFLQNAIGAIPSPFDAWLTHRGLKTLHLRVRQAALSANKIAEFLAADKENVVAVNYPGLKTHPNYDVVLKQHRDALGGGMISFRIKGGAEAASKFASSTRLFTLAESLGGIESLLEVPAVMTHGGIPKEAREASGVFDDLVRISVGIEDTDDLLEDIKQALKQATN
SIO_010081: YAL012W
subclass of: SO_0000673
so part of: YAL012W
location: 130799..131983
location: region:130799-131983:1
so has part: feature:130799-131983:1:exon

NP_009390.1
type: Protein
SIO_000068: ncbiprotein

S000000010
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:130799-131983:1:exon

YAL011W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: SWC1
gene: SWC3
locus tag: YAL011W
gene synonym: SWC1
so part of: sequence
location: <132199..>134076
location: region:132199-134076:1
so has part: feature:132199-134076:1:exon
subclass of: SO_0000010

851222
type: Gene
SIO_000068: ncbigene

position:132199:1
position: 132199
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:134076:1
position: 134076
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:132199-134076:1:exon

YAL011W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: SWC1
gene: SWC3
locus tag: YAL011W
gene synonym: SWC1
product: Swc3p
transcript id: NM_001178156.1
SIO_010081: YAL011W
subclass of: SO_0000673
so part of: YAL011W
location: <132199..>134076
location: region:132199-134076:1
so has part: feature:132199-134076:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:132199-134076:1:exon

YAL011W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: SWC1
gene: SWC3
locus tag: YAL011W
gene synonym: SWC1
experiment: EXISTENCE:direct assay:GO:0000812 Swr1 complex [PMID:14645854|PMID:14690608]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0006338 chromatin remodeling [PMID:14645854]
experiment: EXISTENCE:mutant phenotype:GO:0006338 chromatin remodeling [PMID:14690608]
experiment: EXISTENCE:mutant phenotype:GO:0007029 endoplasmic reticulum organization [PMID:12868057]
note: hypothetical protein; component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A; required for formation of nuclear-associated array of smooth endoplasmic reticulum known as karmellae
codon start: 1
product: Swc3p
translation: MPAVLRTRSKESSIEQKPASRTRTRSRRGKRGRDDDDDDDDEESDDAYDEVGNDYDEYASRAKLATNRPFEIVAGLPASVELPNYNSSLTHPQSIKNSGVLYDSLVSSRRTWVQGEMFELYWRRPKKIVSESTPAATESPTSGTIPLIRDKMQKMCDCVMSGGPHTFKVRLFILKNDKIEQKWQDEQELKKKEKELKRKNDAEAKRLRMEERKRQQMQKKIAKEQKLQLQKENKAKQKLEQEALKLKRKEEMKKLKEQNKNKQGSPSSSMHDPRMIMNLNLMAQEDPKLNTLMETVAKGLANNSQLEEFKKFIEIAKKRSLEENPVNKRPSVTTTRPAPPSKAKDVAEDHRLNSITLVKSSKTAATEPEPKKADDENAEKQQSKEAKTTAESTQVDVKKEEEDVKEKGVKSEDTQKKEDNQVVPKRKRRKNAIKEDKDMQLTAFQQKYVQGAEIILEYLEFTHSRYYLPKKSVVEFLEDTDEIIISWIVIHNSKEIEKFKTKKIKAKLKADQKLNKEDAKPGSDVEKEVSFNPLFEADCPTPLYTPMTMKLSGIHKRFNQIIRNSVSPMEEVVKEMEKILQIGTRLSGYNLWYQLDGYDDEALSESLRFELNEWEHAMRSRRHKR
SIO_010081: YAL011W
subclass of: SO_0000673
so part of: YAL011W
location: 132199..134076
location: region:132199-134076:1
so has part: feature:132199-134076:1:exon

NP_009391.2
type: Protein
SIO_000068: ncbiprotein

S000000009
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:132199-134076:1:exon

YAL010C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: FUN37
gene: MDM10
locus tag: YAL010C
gene synonym: FUN37
so part of: sequence
location: complement(<134184..>135665)
location: region:134184-135665:-1
so has part: feature:134184-135665:-1:exon
subclass of: SO_0000010

851223
type: Gene
SIO_000068: ncbigene

position:134184:-1
position: 134184
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:135665:-1
position: 135665
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:134184-135665:-1:exon

YAL010C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: FUN37
gene: MDM10
locus tag: YAL010C
gene synonym: FUN37
product: Mdm10p
transcript id: NM_001178155.2
SIO_010081: YAL010C
subclass of: SO_0000673
so part of: YAL010C
location: complement(<134184..>135665)
location: region:134184-135665:-1
so has part: feature:134184-135665:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:134184-135665:-1:exon

YAL010C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: FUN37
gene: MDM10
locus tag: YAL010C
gene synonym: FUN37
experiment: EXISTENCE:direct assay:GO:0005741 mitochondrial outer membrane [PMID:16407407]
experiment: EXISTENCE:genetic interaction:GO:0015914 phospholipid transport [PMID:19556461]
experiment: EXISTENCE:mutant phenotype:GO:0007005 mitochondrion organization [PMID:19556461]
experiment: EXISTENCE:mutant phenotype:GO:0007031 peroxisome organization [PMID:30908556]
experiment: EXISTENCE:mutant phenotype:GO:0045040 protein insertion into mitochondrial outer membrane [PMID:17410204]
experiment: EXISTENCE:mutant phenotype:GO:0051654 establishment of mitochondrion localization [PMID:13679517]
experiment: EXISTENCE:mutant phenotype:GO:0070096 mitochondrial outer membrane translocase complex assembly [PMID:20026336|PMID:15239954]
experiment: EXISTENCE:mutant phenotype:GO:1990456 mitochondrion-endoplasmic reticulum membrane tethering [PMID:19556461]
experiment: EXISTENCE:physical interaction:GO:0001401 SAM complex [PMID:17410204]
experiment: EXISTENCE:physical interaction:GO:0032865 ERMES complex [PMID:13679517|PMID:17410204]
experiment: EXISTENCE:physical interaction:GO:0070096 mitochondrial outer membrane translocase complex assembly [PMID:20026336]
note: Subunit of both the ERMES and the SAM complex; component of ERMES complex which acts as a molecular tether between the mitochondria and the ER, necessary for efficient phospholipid exchange between organelles and for mitophagy; SAM/TOB complex component that functions in the assembly of outer membrane beta-barrel proteins; involved in mitochondrial inheritance and morphology; ERMES complex is often co-localized with peroxisomes and concentrated areas of pyruvate dehydrogenase
codon start: 1
product: Mdm10p
translation: MLPYMDQVLRAFYQSTHWSTQNSYEDITATSRTLLDFRIPSAIHLQISNKSTPNTFNSLDFSTRSRINGSLSYLYSDAQQLEKFMRNSTDIPLQDATETYRQLQPNLNFSVSSANTLSSDNTTVDNDKKLLHDSKFVKKSLYYGRMYYPSSDLEAMIIKRLSPQTQFMLKGVSSFKESLNVLTCYFQRDSHRNLQEWIFSTSDLLCGYRVLHNFLTTPSKFNTSLYNNSSLSLGAEFWLGLVSLSPGCSTTLRYYTHSTNTGRPLTLTLSWNPLFGHISSTYSAKTGTNSTFCAKYDFNLYSIESNLSFGCEFWQKKHHLLETNKNNNDKLEPISDELVDINPNSRATKLLHENVPDLNSAVNDIPSTLDIPVHKQKLLNDLTYAFSSSLRKIDEERSTIEKFDNKINSSIFTSVWKLSTSLRDKTLKLLWEGKWRGFLISAGTELVFTRGFQESLSDDEKNDNAISISATDTENGNIPVFPAKFGIQFQYST
SIO_010081: YAL010C
subclass of: SO_0000673
so part of: YAL010C
location: complement(134184..135665)
location: region:134184-135665:-1
so has part: feature:134184-135665:-1:exon

NP_009392.2
type: Protein
SIO_000068: ncbiprotein

S000000008
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:134184-135665:-1:exon

YAL009W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SPO7
locus tag: YAL009W
so part of: sequence
location: <135854..>136633
location: region:135854-136633:1
so has part: feature:135854-136633:1:exon
subclass of: SO_0000010

851224
type: Gene
SIO_000068: ncbigene

position:135854:1
position: 135854
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:136633:1
position: 136633
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:135854-136633:1:exon

YAL009W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: SPO7
locus tag: YAL009W
product: Nem1-Spo7 phosphatase regulatory subunit SPO7
transcript id: NM_001178154.1
SIO_010081: YAL009W
subclass of: SO_0000673
so part of: YAL009W
location: <135854..>136633
location: region:135854-136633:1
so has part: feature:135854-136633:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:135854-136633:1:exon

YAL009W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: SPO7
locus tag: YAL009W
experiment: EXISTENCE:direct assay:GO:0004721 phosphoprotein phosphatase activity [PMID:15889145|PMID:25359770]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0016020 membrane [PMID:9822591]
experiment: EXISTENCE:direct assay:GO:0061709 reticulophagy [PMID:31802527]
experiment: EXISTENCE:direct assay:GO:1903740 positive regulation of phosphatidate phosphatase activity [PMID:25359770]
experiment: EXISTENCE:genetic interaction:GO:0071072 negative regulation of phospholipid biosynthetic process [PMID:15889145]
experiment: EXISTENCE:mutant phenotype:GO:0006998 nuclear envelope organization [PMID:9822591]
experiment: EXISTENCE:mutant phenotype:GO:0071071 regulation of phospholipid biosynthetic process [PMID:30201607]
experiment: EXISTENCE:physical interaction:GO:0071595 Nem1-Spo7 phosphatase complex [PMID:9822591]
note: Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme; regulates nuclear/ER membrane association and activation of Pah1p, a phosphatidate phosphatase involved in the production of diacylglycerol DAG for lipid droplet biogenesis; phosphatase activity of the Nem1p-Spo7p complex is inhibited by Ice2p; regulates nuclear growth by controlling phospholipid biosynthesis; required for normal nuclear envelope morphology, premeiotic replication, and sporulation
codon start: 1
product: Nem1-Spo7 phosphatase regulatory subunit SPO7
translation: MEPESIGDVGNHAQDDSASIVSGPRRRSTSKTSSAKNIRNSSNISPASMIFRNLLILEDDLRRQAHEQKILKWQFTLFLASMAGVGAFTFYELYFTSDYVKGLHRVILQFTLSFISITVVLFHISGQYRRTIVIPRRFFTSTNKGIRQFNVKLVKVQSTWDEKYTDSVRFVSRTIAYCNIYCLKKFLWLKDDNAIVKFWKSVTIQSQPRIGAVDVKLVLNPRAFSAEIREGWEIYRDEFWAREGARRRKQAHELRPKSE
SIO_010081: YAL009W
subclass of: SO_0000673
so part of: YAL009W
location: 135854..136633
location: region:135854-136633:1
so has part: feature:135854-136633:1:exon

NP_009393.1
type: Protein
SIO_000068: ncbiprotein

S000000007
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:135854-136633:1:exon

YAL008W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: MCP3
gene: FUN14
locus tag: YAL008W
gene synonym: MCP3
so part of: sequence
location: <136914..>137510
location: region:136914-137510:1
so has part: feature:136914-137510:1:exon
subclass of: SO_0000010

851225
type: Gene
SIO_000068: ncbigene

position:136914:1
position: 136914
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:137510:1
position: 137510
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:136914-137510:1:exon

YAL008W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: MCP3
gene: FUN14
locus tag: YAL008W
gene synonym: MCP3
product: Fun14p
transcript id: NM_001178153.1
SIO_010081: YAL008W
subclass of: SO_0000673
so part of: YAL008W
location: <136914..>137510
location: region:136914-137510:1
so has part: feature:136914-137510:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:136914-137510:1:exon

YAL008W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: MCP3
gene: FUN14
locus tag: YAL008W
gene synonym: MCP3
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14562095|PMID:24769239|PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005741 mitochondrial outer membrane [PMID:27226123|PMID:16407407]
experiment: EXISTENCE:genetic interaction:GO:0007005 mitochondrion organization [PMID:27226123]
experiment: EXISTENCE:genetic interaction:GO:0055091 phospholipid homeostasis [PMID:27226123]
note: Integral mitochondrial outer membrane (MOM) protein; dosage suppressor of an MDM10 null that reduces ERMES-related phenotypes, such as alterations in mitochondrial morphology, protein complex assembly, and lipid profile; dosage suppressor of MDM12, MDM34, and MMM1 null mutant growth defects; novel mechanism of MOM import involving Tom70p, the TOM complex, and the TIM23 complex, requiring mitochondrial membrane potential and processing by the IMP complex for correct biogenesis
codon start: 1
product: Fun14p
translation: MTLAFNMQRLVFRNLNVGKRMFKNVPLWRFNVANKLGKPLTRSVGLGGAGIVAGGFYLMNRQPSKLIFNDSLGAAVKQQGPLEPTVGNSTAITEERRNKISSHKQMFLGSLFGVVLGVTVAKISILFMYVGITSMLLCEWLRYKGWIRINLKNIKSVIVLKDVDLKKLLIDGLLGTEYMGFKVFFTLSFVLASLNANK
SIO_010081: YAL008W
subclass of: SO_0000673
so part of: YAL008W
location: 136914..137510
location: region:136914-137510:1
so has part: feature:136914-137510:1:exon

NP_009394.1
type: Protein
SIO_000068: ncbiprotein

S000000006
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:136914-137510:1:exon

YAL007C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ERP2
locus tag: YAL007C
so part of: sequence
location: complement(<137698..>138345)
location: region:137698-138345:-1
so has part: feature:137698-138345:-1:exon
subclass of: SO_0000010

851226
type: Gene
SIO_000068: ncbigene

position:137698:-1
position: 137698
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:138345:-1
position: 138345
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:137698-138345:-1:exon

YAL007C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ERP2
locus tag: YAL007C
product: Erp2p
transcript id: NM_001178152.1
SIO_010081: YAL007C
subclass of: SO_0000673
so part of: YAL007C
location: complement(<137698..>138345)
location: region:137698-138345:-1
so has part: feature:137698-138345:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:137698-138345:-1:exon

YAL007C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ERP2
locus tag: YAL007C
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0030134 COPII-coated ER to Golgi transport vesicle [PMID:11157978]
experiment: EXISTENCE:mutant phenotype:GO:0006621 protein retention in ER lumen [PMID:10359606]
experiment: EXISTENCE:mutant phenotype:GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport [PMID:10359606]
note: Member of the p24 family involved in ER to Golgi transport; similar to Emp24p and Erv25p; role in misfolded protein quality control; forms a heterotrimeric complex with Erp1p, Emp24p, and Erv25p; localized to COPII-coated vesicles; ERP2 has a paralog, ERP4, that arose from the whole genome duplication
codon start: 1
product: Erp2p
translation: MIKSTIALPSFFIVLILALVNSVAASSSYAPVAISLPAFSKECLYYDMVTEDDSLAVGYQVLTGGNFEIDFDITAPDGSVITSEKQKKYSDFLLKSFGVGKYTFCFSNNYGTALKKVEITLEKEKTLTDEHEADVNNDDIIANNAVEEIDRNLNKITKTLNYLRAREWRNMSTVNSTESRLTWLSILIIIIIAVISIAQVLLIQFLFTGRQKNYV
SIO_010081: YAL007C
subclass of: SO_0000673
so part of: YAL007C
location: complement(137698..138345)
location: region:137698-138345:-1
so has part: feature:137698-138345:-1:exon

NP_009395.1
type: Protein
SIO_000068: ncbiprotein

S000000005
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:137698-138345:-1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(138831..138992)
location: region:138831-138992:-1
so has part: feature:138831-138992:-1:region

S000006786
type: SGD
SIO_000068: sgd

position:138831:-1
position: 138831
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:138992:-1
position: 138992
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:138831-138992:-1:region

YNCA0002W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TRN1
locus tag: YNCA0002W
so part of: sequence
location: 139152..139254
location: region:139152-139254:1
so has part: feature:139152-139254:1:exon
subclass of: SO_0000663

851227
type: Gene
SIO_000068: ncbigene

position:139152:1
position: 139152
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:139254:1
position: 139254
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:139152-139254:1:exon

YNCA0002W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
gene: TRN1
locus tag: YNCA0002W
product: tRNA-Pro
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Proline tRNA (tRNA-Pro), predicted by tRNAscan-SE analysis; target of K. lactis zymocin; can mutate to suppress +1 frameshift mutations in proline codons
SIO_010081: YNCA0002W
subclass of: SO_0000673
so part of: YNCA0002W
location: join(139152..139187,139219..139254)
location: region:139152-139254:1
so has part: feature:139152-139187:1:exon
so has part: feature:139219-139254:1:exon

S000006680
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:139152-139187:1:exon

position:139187:1
position: 139187
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:139219-139254:1:exon

position:139219:1
position: 139219
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YAL005C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YG100
gene: SSA1
locus tag: YAL005C
gene synonym: YG100
so part of: sequence
location: complement(<139503..>141431)
location: region:139503-141431:-1
so has part: feature:139503-141431:-1:exon
subclass of: SO_0000010

851259
type: Gene
SIO_000068: ncbigene

position:139503:-1
position: 139503
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:141431:-1
position: 141431
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:139503-141431:-1:exon

YAL005C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YG100
gene: SSA1
locus tag: YAL005C
gene synonym: YG100
product: Hsp70 family ATPase SSA1
transcript id: NM_001178151.1
SIO_010081: YAL005C
subclass of: SO_0000673
so part of: YAL005C
location: complement(<139503..>141431)
location: region:139503-141431:-1
so has part: feature:139503-141431:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:139503-141431:-1:exon

YAL005C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: YG100
gene: SSA1
locus tag: YAL005C
gene synonym: YG100
experiment: EXISTENCE:direct assay:GO:0000049 tRNA binding [PMID:25853343]
experiment: EXISTENCE:direct assay:GO:0000209 protein polyubiquitination [PMID:20462952]
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:10745074]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:10347213|PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:8755907|PMID:11914276]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005844 polysome [PMID:16413483]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:16622836]
experiment: EXISTENCE:direct assay:GO:0006457 protein folding [PMID:8947547]
experiment: EXISTENCE:direct assay:GO:0006606 protein import into nucleus [PMID:10347213]
experiment: EXISTENCE:direct assay:GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation [PMID:8754838]
experiment: EXISTENCE:direct assay:GO:0009277 fungal-type cell wall [PMID:8755907]
experiment: EXISTENCE:direct assay:GO:0016887 ATP hydrolysis activity [PMID:7737974|PMID:18706386]
experiment: EXISTENCE:direct assay:GO:0035617 stress granule disassembly [PMID:24291094]
experiment: EXISTENCE:direct assay:GO:0042026 protein refolding [PMID:18706386|PMID:9674429]
experiment: EXISTENCE:direct assay:GO:0051082 unfolded protein binding [PMID:9789005]
experiment: EXISTENCE:direct assay:GO:0072318 clathrin coat disassembly [PMID:23913685]
experiment: EXISTENCE:genetic interaction:GO:0006606 protein import into nucleus [PMID:10347213]
experiment: EXISTENCE:genetic interaction:GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process [PMID:27178214]
experiment: EXISTENCE:mutant phenotype:GO:0002181 cytoplasmic translation [PMID:11279042]
experiment: EXISTENCE:mutant phenotype:GO:0006626 protein targeting to mitochondrion [PMID:8754838]
experiment: EXISTENCE:mutant phenotype:GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process [PMID:27178214]
experiment: EXISTENCE:mutant phenotype:GO:0072671 mitochondria-associated ubiquitin-dependent protein catabolic process [PMID:32118579]
note: ATPase involved in protein folding and NLS-directed nuclear transport; member of HSP70 family; required for ubiquitin-dependent degradation of short-lived proteins; forms chaperone complex with Ydj1p; localized to nucleus, cytoplasm, cell wall; 98% identical to paralog Ssa2p with different functional specificity in propagation of yeast [URE3] prions, vacuolar-mediated degradations of gluconeogenesis enzymes; general targeting factor of Hsp104p to prion fibrils
codon start: 1
product: Hsp70 family ATPase SSA1
translation: MSKAVGIDLGTTYSCVAHFANDRVDIIANDQGNRTTPSFVAFTDTERLIGDAAKNQAAMNPSNTVFDAKRLIGRNFNDPEVQADMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKETAESYLGAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKGKEEHVLIFDLGGGTFDVSLLSIEDGIFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLRTACERAKRTLSSSAQTSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRDAKLDKSQVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGDESSKTQDLLLLDVAPLSLGIETAGGVMTKLIPRNSTIPTKKSEIFSTYADNQPGVLIQVFEGERAKTKDNNLLGKFELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLSKEDIEKMVAEAEKFKEEDEKESQRIASKNQLESIAYSLKNTISEAGDKLEQADKDTVTKKAEETISWLDSNTTASKEEFDDKLKELQDIANPIMSKLYQAGGAPGGAAGGAPGGFPGGAPPAPEAEGPTVEEVD
SIO_010081: YAL005C
subclass of: SO_0000673
so part of: YAL005C
location: complement(139503..141431)
location: region:139503-141431:-1
so has part: feature:139503-141431:-1:exon

NP_009396.2
type: Protein
SIO_000068: ncbiprotein

S000000004
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:139503-141431:-1:exon

YAL003W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: TEF5
gene: EFB1
locus tag: YAL003W
gene synonym: TEF5
so part of: sequence
location: <142174..>143160
location: region:142174-143160:1
so has part: feature:142174-143160:1:exon
subclass of: SO_0000010

851260
type: Gene
SIO_000068: ncbigene

position:142174:1
position: 142174
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:143160:1
position: 143160
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:142174-143160:1:exon

YAL003W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: TEF5
gene: EFB1
locus tag: YAL003W
gene synonym: TEF5
product: translation elongation factor 1 subunit beta
transcript id: NM_001178150.1
SIO_010081: YAL003W
subclass of: SO_0000673
so part of: YAL003W
location: join(<142174..142253,142620..>143160)
location: region:142174-143160:1
so has part: feature:142174-142253:1:exon
so has part: feature:142620-143160:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:142174-142253:1:exon

position:142253:1
position: 142253
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:142620-143160:1:exon

position:142620:1
position: 142620
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YAL003W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: TEF5
gene: EFB1
locus tag: YAL003W
gene synonym: TEF5
experiment: EXISTENCE:direct assay:GO:0005085 guanyl-nucleotide exchange factor activity [PMID:17925388]
experiment: EXISTENCE:direct assay:GO:0032232 negative regulation of actin filament bundle assembly [PMID:19095653]
experiment: EXISTENCE:genetic interaction:GO:0006449 regulation of translational termination [PMID:19545407]
experiment: EXISTENCE:mutant phenotype:GO:0005853 eukaryotic translation elongation factor 1 complex [PMID:8420802]
experiment: EXISTENCE:mutant phenotype:GO:0006414 translational elongation [PMID:10409717]
experiment: EXISTENCE:mutant phenotype:GO:1990145 maintenance of translational fidelity [PMID:10409717]
note: Translation elongation factor 1 beta; stimulates nucleotide exchange to regenerate EF-1 alpha-GTP for the next elongation cycle; part of the EF-1 complex, which facilitates binding of aminoacyl-tRNA to the ribosomal A site; human homolog EEF1B2 can complement yeast efb1 mutants
codon start: 1
product: translation elongation factor 1 subunit beta
translation: MASTDFSKIETLKQLNASLADKSYIEGTAVSQADVTVFKAFQSAYPEFSRWFNHIASKADEFDSFPAASAAAAEEEEDDDVDLFGSDDEEADAEAEKLKAERIAAYNAKKAAKPAKPAAKSIVTLDVKPWDDETNLEEMVANVKAIEMEGLTWGAHQFIPIGFGIKKLQINCVVEDDKVSLDDLQQSIEEDEDHVQSTDIAAMQKL
SIO_010081: YAL003W
subclass of: SO_0000673
so part of: YAL003W
location: join(142174..142253,142620..143160)
location: region:142174-143160:1
so has part: feature:142174-142253:1:exon
so has part: feature:142620-143160:1:exon

NP_009398.1
type: Protein
SIO_000068: ncbiprotein

S000000003
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:142174-142253:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:142620-143160:1:exon

YNCA0003W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SNR18
locus tag: YNCA0003W
so part of: sequence
location: 142367..142468
location: region:142367-142468:1
so has part: feature:142367-142468:1:exon
subclass of: SO_0000578

9164867
type: Gene
SIO_000068: ncbigene

position:142367:1
position: 142367
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:142468:1
position: 142468
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:142367-142468:1:exon

YNCA0003W
type: Non Coding RNA
subclass of: SO_0000655
RO_0002162: 559292
nc RNA class: snoRNA
gene: SNR18
locus tag: YNCA0003W
product: SNR18
experiment: EXISTENCE:curator inference:GO:0005730 nucleolus [PMID:8674114]
experiment: EXISTENCE:direct assay:GO:0031428 box C/D RNP complex [PMID:10094313]
experiment: EXISTENCE:physical interaction:GO:0031428 box C/D RNP complex [PMID:10733567]
note: C/D box small nucleolar RNA (snoRNA); commonly referred to as U18; guides 2'-O-methylation of large subunit (LSU) rRNA at positions A649 and C650
transcript id: NR_132150.1
SIO_010081: YNCA0003W
subclass of: SO_0000673
so part of: YNCA0003W
location: 142367..142468
location: region:142367-142468:1
so has part: feature:142367-142468:1:exon

S000007500
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:142367-142468:1:exon

YAL002W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: FUN15
alternative label: VPL8
alternative label: VPT8
gene: VPS8
locus tag: YAL002W
gene synonym: FUN15; VPL8; VPT8
so part of: sequence
location: <143707..>147531
location: region:143707-147531:1
so has part: feature:143707-147531:1:exon
subclass of: SO_0000010

851261
type: Gene
SIO_000068: ncbigene

position:143707:1
position: 143707
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:147531:1
position: 147531
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:143707-147531:1:exon

YAL002W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: FUN15
alternative label: VPL8
alternative label: VPT8
gene: VPS8
locus tag: YAL002W
gene synonym: FUN15; VPL8; VPT8
product: CORVET complex membrane-binding subunit VPS8
transcript id: NM_001178149.1
SIO_010081: YAL002W
subclass of: SO_0000673
so part of: YAL002W
location: <143707..>147531
location: region:143707-147531:1
so has part: feature:143707-147531:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:143707-147531:1:exon

YAL002W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: FUN15
alternative label: VPL8
alternative label: VPT8
gene: VPS8
locus tag: YAL002W
gene synonym: FUN15; VPL8; VPT8
experiment: EXISTENCE:direct assay:GO:0005770 late endosome [PMID:19828734]
experiment: EXISTENCE:direct assay:GO:0016020 membrane [PMID:8969229]
experiment: EXISTENCE:direct assay:GO:0033263 CORVET complex [PMID:17488625]
experiment: EXISTENCE:direct assay:GO:0051020 GTPase binding [PMID:19828734]
experiment: EXISTENCE:mutant phenotype:GO:0006623 protein targeting to vacuole [PMID:20173035]
experiment: EXISTENCE:mutant phenotype:GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway [PMID:19828734]
experiment: EXISTENCE:mutant phenotype:GO:0043495 protein-membrane adaptor activity [PMID:19828734]
experiment: EXISTENCE:physical interaction:GO:0051020 GTPase binding [PMID:19828734]
note: Membrane-binding component of the CORVET complex; involved in endosomal vesicle tethering and fusion in the endosome to vacuole protein targeting pathway; interacts with Vps21p; contains RING finger motif
codon start: 1
product: CORVET complex membrane-binding subunit VPS8
translation: MEQNGLDHDSRSSIDTTINDTQKTFLEFRSYTQLSEKLASSSSYTAPPLNEDGPKGVASAVSQGSESVVSWTTLTHVYSILGAYGGPTCLYPTATYFLMGTSKGCVLIFNYNEHLQTILVPTLSEDPSIHSIRSPVKSIVICSDGTHVAASYETGNICIWNLNVGYRVKPTSEPTNGMTPTPALPAVLHIDDHVNKEITGLDFFGARHTALIVSDRTGKVSLYNGYRRGFWQLVYNSKKILDVNSSKEKLIRSKLSPLISREKISTNLLSVLTTTHFALILLSPHVSLMFQETVEPSVQNSLVVNSSISWTQNCSRVAYSVNNKISVISISSSDFNVQSASHSPEFAESILSIQWIDQLLLGVLTISHQFLVLHPQHDFKILLRLDFLIHDLMIPPNKYFVISRRSFYLLTNYSFKIGKFVSWSDITLRHILKGDYLGALEFIESLLQPYCPLANLLKLDNNTEERTKQLMEPFYNLSLAALRFLIKKDNADYNRVYQLLMVVVRVLQQSSKKLDSIPSLDVFLEQGLEFFELKDNAVYFEVVANIVAQGSVTSISPVLFRSIIDYYAKEENLKVIEDLIIMLNPTTLDVDLAVKLCQKYNLFDLLIYIWNKIFDDYQTPVVDLIYRISNQSEKCVIFNGPQVPPETTIFDYVTYILTGRQYPQNLSISPSDKCSKIQRELSAFIFSGFSIKWPSNSNHKLYICENPEEEPAFPYFHLLLKSNPSRFLAMLNEVFEASLFNDDNDMVASVGEAELVSRQYVIDLLLDAMKDTGNSDNIRVLVAIFIATSISKYPQFIKVSNQALDCVVNTICSSRVQGIYEISQIALESLLPYYHSRTTENFILELKEKNFNKVLFHIYKSENKYASALSLILETKDIEKEYNTDIVSITDYILKKCPPGSLECGKVTEVIETNFDLLLSRIGIEKCVTIFSDFDYNLHQEILEVKNEETQQKYLDKLFSTPNINNKVDKRLRNLHIELNCKYKSKREMILWLNGTVLSNAESLQILDLLNQDSNFEAAAIIHERLESFNLAVRDLLSFIEQCLNEGKTNISTLLESLRRAFDDCNSAGTEKKSCWILLITFLITLYGKYPSHDERKDLCNKLLQEAFLGLVRSKSSSQKDSGGEFWEIMSSVLEHQDVILMKVQDLKQLLLNVFNTYKLERSLSELIQKIIEDSSQDLVQQYRKFLSEGWSIHTDDCEICGKKIWGAGLDPLLFLAWENVQRHQDMISVDLKTPLVIFKCHHGFHQTCLENLAQKPDEYSCLICQTESNPKIV
SIO_010081: YAL002W
subclass of: SO_0000673
so part of: YAL002W
location: 143707..147531
location: region:143707-147531:1
so has part: feature:143707-147531:1:exon

NP_009399.2
type: Protein
SIO_000068: ncbiprotein

S000000002
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:143707-147531:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS108; Autonomously Replicating Sequence
so part of: sequence
location: 147398..147717
location: region:147398-147717:1
so has part: feature:147398-147717:1:region

S000121255
type: SGD
SIO_000068: sgd

position:147398:1
position: 147398
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:147717:1
position: 147717
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:147398-147717:1:region

YAL001C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: FUN24
alternative label: TSV115
gene: TFC3
locus tag: YAL001C
gene synonym: FUN24; TSV115
so part of: sequence
location: complement(<147594..>151166)
location: region:147594-151166:-1
so has part: feature:147594-151166:-1:exon
subclass of: SO_0000010

851262
type: Gene
SIO_000068: ncbigene

position:147594:-1
position: 147594
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:151166:-1
position: 151166
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:147594-151166:-1:exon

YAL001C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: FUN24
alternative label: TSV115
gene: TFC3
locus tag: YAL001C
gene synonym: FUN24; TSV115
product: transcription factor TFIIIC subunit TFC3
transcript id: NM_001178148.1
SIO_010081: YAL001C
subclass of: SO_0000673
so part of: YAL001C
location: complement(join(<147594..151006,151097..>151166))
location: region:147594-151166:-1
so has part: feature:151097-151166:-1:exon
so has part: feature:147594-151006:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:151097-151166:-1:exon

position:151097:-1
position: 151097
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:147594-151006:-1:exon

position:151006:-1
position: 151006
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

YAL001C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: FUN24
alternative label: TSV115
gene: TFC3
locus tag: YAL001C
gene synonym: FUN24; TSV115
experiment: EXISTENCE:direct assay:GO:0000127 transcription factor TFIIIC complex [PMID:1279682|PMID:1474578|PMID:2002052|PMID:2180956]
experiment: EXISTENCE:direct assay:GO:0001002 RNA polymerase III type 1 promoter sequence-specific DNA binding [PMID:2404611|PMID:2649882]
experiment: EXISTENCE:direct assay:GO:0001003 RNA polymerase III type 2 promoter sequence-specific DNA binding [PMID:2404611]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0006383 transcription by RNA polymerase III [PMID:3633923|PMID:8464480|PMID:2183033]
experiment: EXISTENCE:direct assay:GO:0008301 DNA binding, bending [PMID:2002052]
experiment: EXISTENCE:direct assay:GO:0042791 5S class rRNA transcription by RNA polymerase III [PMID:2183033]
experiment: EXISTENCE:mutant phenotype:GO:0042791 5S class rRNA transcription by RNA polymerase III [PMID:8083243]
experiment: EXISTENCE:mutant phenotype:GO:0071168 protein localization to chromatin [PMID:18708580]
note: Subunit of RNA polymerase III transcription initiation factor complex; part of TauB domain of TFIIIC that binds DNA at BoxB promoter sites of tRNA and similar genes; cooperates with Tfc6p in DNA binding; largest of six subunits of RNA polymerase III transcription initiation factor complex (TFIIIC); colocalizes with condensin at pol III genes and several ETC (extra TFIIIC) sites; may have a role in recruiting or stabilizing Scc2/4 and condensin on chromosomes
codon start: 1
product: transcription factor TFIIIC subunit TFC3
translation: MVLTIYPDELVQIVSDKIASNKGKITLNQLWDISGKYFDLSDKKVKQFVLSCVILKKDIEVYCDGAITTKNVTDIIGDANHSYSVGITEDSLWTLLTGYTKKESTIGNSAFELLLEVAKSGEKGINTMDLAQVTGQDPRSVTGRIKKINHLLTSSQLIYKGHVVKQLKLKKFSHDGVDSNPYINIRDHLATIVEVVKRSKNGIRQIIDLKRELKFDKEKRLSKAFIAAIAWLDEKEYLKKVLVVSPKNPAIKIRCVKYVKDIPDSKGSPSFEYDSNSADEDSVSDSKAAFEDEDLVEGLDNFNATDLLQNQGLVMEEKEDAVKNEVLLNRFYPLQNQTYDIADKSGLKGISTMDVVNRITGKEFQRAFTKSSEYYLESVDKQKENTGGYRLFRIYDFEGKKKFFRLFTAQNFQKLTNAEDEISVPKGFDELGKSRTDLKTLNEDNFVALNNTVRFTTDSDGQDIFFWHGELKIPPNSKKTPNKNKRKRQVKNSTNASVAGNISNPKRIKLEQHVSTAQEPKSAEDSPSSNGGTVVKGKVVNFGGFSARSLRSLQRQRAILKVMNTIGGVAYLREQFYESVSKYMGSTTTLDKKTVRGDVDLMVESEKLGARTEPVSGRKIIFLPTVGEDAIQRYILKEKDSKKATFTDVIHDTEIYFFDQTEKNRFHRGKKSVERIRKFQNRQKNAKIKASDDAISKKSTSVNVSDGKIKRRDKKVSAGRTTVVVENTKEDKTVYHAGTKDGVQALIRAVVVTKSIKNEIMWDKITKLFPNNSLDNLKKKWTARRVRMGHSGWRAYVDKWKKMLVLAIKSEKISLRDVEELDLIKLLDIWTSFDEKEIKRPLFLYKNYEENRKKFTLVRDDTLTHSGNDLAMSSMIQREISSLKKTYTRKISASTKDLSKSQSDDYIRTVIRSILIESPSTTRNEIEALKNVGNESIDNVIMDMAKEKQIYLHGSKLECTDTLPDILENRGNYKDFGVAFQYRCKVNELLEAGNAIVINQEPSDISSWVLIDLISGELLNMDVIPMVRNVRPLTYTSRRFEIRTLTPPLIIYANSQTKLNTARKSAVKVPLGKPFSRLWVNGSGSIRPNIWKQVVTMVVNEIIFHPGITLSRLQSRCREVLSLHEISEICKWLLERQVLITTDFDGYWVNHNWYSIYEST
SIO_010081: YAL001C
subclass of: SO_0000673
so part of: YAL001C
location: complement(join(147594..151006,151097..151166))
location: region:147594-151166:-1
so has part: feature:151097-151166:-1:exon
so has part: feature:147594-151006:-1:exon

NP_009400.1
type: Protein
SIO_000068: ncbiprotein

S000000001
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:151097-151166:-1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:147594-151006:-1:exon

centromere
type: Centromere
subclass of: SO_0000577
RO_0002162: 559292
note: CEN1; Chromosome I centromere
so part of: sequence
location: 151465..151582
location: region:151465-151582:1
so has part: feature:151465-151582:1:region

S000006463
type: SGD
SIO_000068: sgd

position:151465:1
position: 151465
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:151582:1
position: 151582
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:151465-151582:1:region

centromere
type: Centromere
subclass of: SO_0000577
RO_0002162: 559292
note: CEN1_CDEI of CEN1
so part of: sequence
location: 151465..151474
location: region:151465-151474:1
so has part: feature:151465-151474:1:region

position:151474:1
position: 151474
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:151465-151474:1:region

centromere
type: Centromere
subclass of: SO_0000577
RO_0002162: 559292
note: CEN1_CDEII of CEN1
so part of: sequence
location: 151475..151557
location: region:151475-151557:1
so has part: feature:151475-151557:1:region

position:151475:1
position: 151475
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:151557:1
position: 151557
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:151475-151557:1:region

centromere
type: Centromere
subclass of: SO_0000577
RO_0002162: 559292
note: CEN1_CDEIII of CEN1
so part of: sequence
location: 151558..151582
location: region:151558-151582:1
so has part: feature:151558-151582:1:region

position:151558:1
position: 151558
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:151558-151582:1:region

YAR002W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: NUP60
locus tag: YAR002W
so part of: sequence
location: <152257..>153876
location: region:152257-153876:1
so has part: feature:152257-153876:1:exon
subclass of: SO_0000010

851263
type: Gene
SIO_000068: ncbigene

position:152257:1
position: 152257
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:153876:1
position: 153876
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:152257-153876:1:exon

YAR002W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: NUP60
locus tag: YAR002W
product: FG-nucleoporin NUP60
transcript id: NM_001178209.1
SIO_010081: YAR002W
subclass of: SO_0000673
so part of: YAR002W
location: <152257..>153876
location: region:152257-153876:1
so has part: feature:152257-153876:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:152257-153876:1:exon

YAR002W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: NUP60
locus tag: YAR002W
experiment: EXISTENCE:direct assay:GO:0005543 phospholipid binding [PMID:17897934]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0005643 nuclear pore [PMID:10684247]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0044613 nuclear pore central transport channel [PMID:18046406]
experiment: EXISTENCE:direct assay:GO:0044615 nuclear pore nuclear basket [PMID:10684247]
experiment: EXISTENCE:genetic interaction:GO:0006607 NLS-bearing protein import into nucleus [PMID:15039779]
experiment: EXISTENCE:genetic interaction:GO:0017056 structural constituent of nuclear pore [PMID:11387327]
experiment: EXISTENCE:genetic interaction:GO:0060188 regulation of protein desumoylation [PMID:17403926]
experiment: EXISTENCE:mutant phenotype:GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery [PMID:20098417|PMID:20932479|PMID:21036941]
experiment: EXISTENCE:mutant phenotype:GO:0000973 post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery [PMID:20932479]
experiment: EXISTENCE:mutant phenotype:GO:0006302 double-strand break repair [PMID:17538013]
experiment: EXISTENCE:mutant phenotype:GO:0006607 NLS-bearing protein import into nucleus [PMID:11535617]
experiment: EXISTENCE:mutant phenotype:GO:0006611 protein export from nucleus [PMID:11535617]
experiment: EXISTENCE:mutant phenotype:GO:0006913 nucleocytoplasmic transport [PMID:11535617]
experiment: EXISTENCE:mutant phenotype:GO:0008298 intracellular mRNA localization [PMID:21036941]
experiment: EXISTENCE:mutant phenotype:GO:0016973 poly(A)+ mRNA export from nucleus [PMID:12411502|PMID:21036941]
experiment: EXISTENCE:mutant phenotype:GO:0017056 structural constituent of nuclear pore [PMID:17418788]
experiment: EXISTENCE:mutant phenotype:GO:0030466 silent mating-type cassette heterochromatin formation [PMID:21818277]
experiment: EXISTENCE:mutant phenotype:GO:0031990 mRNA export from nucleus in response to heat stress [PMID:18258809]
experiment: EXISTENCE:mutant phenotype:GO:0034398 telomere tethering at nuclear periphery [PMID:11862215|PMID:21818277]
experiment: EXISTENCE:mutant phenotype:GO:0051276 chromosome organization [PMID:21818277]
experiment: EXISTENCE:physical interaction:GO:0017056 structural constituent of nuclear pore [PMID:17418788]
note: FG-nucleoporin component of central core of the nuclear pore complex; contributes directly to nucleocytoplasmic transport and maintenance of the nuclear pore complex (NPC) permeability barrier; involved in gene tethering at the nuclear periphery; relocalizes to the cytosol in response to hypoxia; both NUP1 and NUP60 are homologous to human NUP153
codon start: 1
product: FG-nucleoporin NUP60
translation: MHRKSLRRASATVPSAPYRKQIISNAHNKPSLFSKIKTFFTQKDSARVSPRNNVANKQPRNESFNRRISSMPGGYFHSEISPDSTVNRSVVVSAVGEARNDIENKEEEYDETHETNISNAKLANFFSKKGNEPLSEIEIEGVMSLLQKSSKSMITSEGEQKSAEGNNIDQSLILKESGSTPISISNAPTFNPKYDTSNASMNTTLGSIGSRKYSFNYSSLPSPYKTTVYRYSAAKKIPDTYTANTSAQSIASAKSVRSGVSKSAPSKKISNTAAALVSLLDENDSKKNNAASELANPYSSYVSQIRKHKRVSPNAAPRQEISEEETTVKPLFQNVPEQGEEPMKQLNATKISPSAPSKDSFTKYKPARSSSLRSNVVVAETSPEKKDGGDKPPSSAFNFSFNTSRNVEPTENAYKSENAPSASSKEFNFTNLQAKPLVGKPKTELTKGDSTPVQPDLSVTPQKSSSKGFVFNSVQKKSRSNLSQENDNEGKHISASIDNDFSEEKAEEFDFNVPVVSKQLGNGLVDENKVEAFKSLYTF
SIO_010081: YAR002W
subclass of: SO_0000673
so part of: YAR002W
location: 152257..153876
location: region:152257-153876:1
so has part: feature:152257-153876:1:exon

NP_009401.1
type: Protein
SIO_000068: ncbiprotein

S000000063
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:152257-153876:1:exon

YAR002C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ERP1
locus tag: YAR002C-A
so part of: sequence
location: complement(<154065..>154724)
location: region:154065-154724:-1
so has part: feature:154065-154724:-1:exon
subclass of: SO_0000010

851264
type: Gene
SIO_000068: ncbigene

position:154065:-1
position: 154065
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:154724:-1
position: 154724
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:154065-154724:-1:exon

YAR002C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ERP1
locus tag: YAR002C-A
product: Erp1p
transcript id: NM_001180033.1
SIO_010081: YAR002C-A
subclass of: SO_0000673
so part of: YAR002C-A
location: complement(<154065..>154724)
location: region:154065-154724:-1
so has part: feature:154065-154724:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:154065-154724:-1:exon

YAR002C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ERP1
locus tag: YAR002C-A
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:14576278|PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0030134 COPII-coated ER to Golgi transport vesicle [PMID:11157978]
experiment: EXISTENCE:mutant phenotype:GO:0006621 protein retention in ER lumen [PMID:10359606]
experiment: EXISTENCE:mutant phenotype:GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport [PMID:10359606]
experiment: EXISTENCE:physical interaction:GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport [PMID:11157978]
note: Member of the p24 family involved in ER to Golgi transport; role in misfolded protein quality control; forms heterotrimeric complex with Erp2p, Emp24p, and Erv25p; localized to COPII-coated vesicles; ERP1 has a paralog, ERP6, that arose from the whole genome duplication
codon start: 1
product: Erp1p
translation: MLLTSLLQVFACCLVLPAQVTAFYYYTSGAERKCFHKELSKGTLFQATYKAQIYDDQLQNYRDAGAQDFGVLIDIEETFDDNHLVVHQKGSASGDLTFLASDSGEHKICIQPEAGGWLIKAKTKIDVEFQVGSDEKLDSKGKATIDILHAKVNVLNSKIGEIRREQKLMRDREATFRDASEAVNSRAMWWIVIQLIVLAVTCGWQMKHLGKFFVKQKIL
SIO_010081: YAR002C-A
subclass of: SO_0000673
so part of: YAR002C-A
location: complement(154065..154724)
location: region:154065-154724:-1
so has part: feature:154065-154724:-1:exon

NP_009402.1
type: Protein
SIO_000068: ncbiprotein

S000002129
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:154065-154724:-1:exon

YAR003W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: CPS50
alternative label: FUN16
alternative label: SAF49
gene: SWD1
locus tag: YAR003W
gene synonym: CPS50; FUN16; SAF49
so part of: sequence
location: <155005..>156285
location: region:155005-156285:1
so has part: feature:155005-156285:1:exon
subclass of: SO_0000010

851265
type: Gene
SIO_000068: ncbigene

position:155005:1
position: 155005
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:156285:1
position: 156285
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:155005-156285:1:exon

YAR003W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: CPS50
alternative label: FUN16
alternative label: SAF49
gene: SWD1
locus tag: YAR003W
gene synonym: CPS50; FUN16; SAF49
product: COMPASS subunit protein SWD1
transcript id: NM_001178210.1
SIO_010081: YAR003W
subclass of: SO_0000673
so part of: YAR003W
location: <155005..>156285
location: region:155005-156285:1
so has part: feature:155005-156285:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:155005-156285:1:exon

YAR003W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: CPS50
alternative label: FUN16
alternative label: SAF49
gene: SWD1
locus tag: YAR003W
gene synonym: CPS50; FUN16; SAF49
experiment: EXISTENCE:direct assay:GO:0042800 histone H3K4 methyltransferase activity [PMID:11742990|PMID:11805083]
experiment: EXISTENCE:mutant phenotype:GO:0000723 telomere maintenance [PMID:11742990]
experiment: EXISTENCE:mutant phenotype:GO:0006355 regulation of DNA-templated transcription [PMID:11687631]
experiment: EXISTENCE:mutant phenotype:GO:0031509 subtelomeric heterochromatin formation [PMID:11687631|PMID:11752412|PMID:11805083]
experiment: EXISTENCE:mutant phenotype:GO:0042800 histone H3K4 methyltransferase activity [PMID:11752412|PMID:11805083]
experiment: EXISTENCE:physical interaction:GO:0048188 Set1C/COMPASS complex [PMID:11687631|PMID:11742990|PMID:11752412]
note: Subunit of the COMPASS (Set1C) complex; COMPASS methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member with similarity to mammalian Rbbp7
codon start: 1
product: COMPASS subunit protein SWD1
translation: MNILLQDPFAVLKEHPEKLTHTIENPLRTECLQFSPCGDYLALGCANGALVIYDMDTFRPICVPGNMLGAHVRPITSIAWSPDGRLLLTSSRDWSIKLWDLSKPSKPLKEIRFDSPIWGCQWLDAKRRLCVATIFEESDAYVIDFSNDPVASLLSKSDEKQLSSTPDHGYVLVCTVHTKHPNIIIVGTSKGWLDFYKFHSLYQTECIHSLKITSSNIKHLIVSQNGERLAINCSDRTIRQYEISIDDENSAVELTLEHKYQDVINKLQWNCILFSNNTAEYLVASTHGSSAHELYIWETTSGTLVRVLEGAEEELIDINWDFYSMSIVSNGFESGNVYVWSVVIPPKWSALAPDFEEVEENVDYLEKEDEFDEVDEAEQQQGLEQEEEIAIDLRTREQYDVRGNNLLVERFTIPTDYTRIIKMQSS
SIO_010081: YAR003W
subclass of: SO_0000673
so part of: YAR003W
location: 155005..156285
location: region:155005-156285:1
so has part: feature:155005-156285:1:exon

NP_009403.1
type: Protein
SIO_000068: ncbiprotein

S000000064
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:155005-156285:1:exon

YAR007C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: BUF2
alternative label: FUN3
alternative label: RPA1
alternative label: RPA70
gene: RFA1
locus tag: YAR007C
gene synonym: BUF2; FUN3; RPA1; RPA70
so part of: sequence
location: complement(<156754..>158619)
location: region:156754-158619:-1
so has part: feature:156754-158619:-1:exon
subclass of: SO_0000010

851266
type: Gene
SIO_000068: ncbigene

position:156754:-1
position: 156754
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:158619:-1
position: 158619
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:156754-158619:-1:exon

YAR007C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: BUF2
alternative label: FUN3
alternative label: RPA1
alternative label: RPA70
gene: RFA1
locus tag: YAR007C
gene synonym: BUF2; FUN3; RPA1; RPA70
product: replication factor A subunit protein RFA1
transcript id: NM_001178211.1
SIO_010081: YAR007C
subclass of: SO_0000673
so part of: YAR007C
location: complement(<156754..>158619)
location: region:156754-158619:-1
so has part: feature:156754-158619:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:156754-158619:-1:exon

YAR007C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: BUF2
alternative label: FUN3
alternative label: RPA1
alternative label: RPA70
gene: RFA1
locus tag: YAR007C
gene synonym: BUF2; FUN3; RPA1; RPA70
experiment: EXISTENCE:direct assay:GO:0000794 condensed nuclear chromosome [PMID:9679065]
experiment: EXISTENCE:direct assay:GO:0003690 double-stranded DNA binding [PMID:7761422]
experiment: EXISTENCE:direct assay:GO:0003697 single-stranded DNA binding [PMID:8804316]
experiment: EXISTENCE:direct assay:GO:0003729 mRNA binding [PMID:23222640]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0005662 DNA replication factor A complex [PMID:2554144]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:15282802]
experiment: EXISTENCE:direct assay:GO:0005829 cytosol [PMID:22932476]
experiment: EXISTENCE:direct assay:GO:0006265 DNA topological change [PMID:22885009]
experiment: EXISTENCE:direct assay:GO:0006268 DNA unwinding involved in DNA replication [PMID:2554144]
experiment: EXISTENCE:direct assay:GO:0006289 nucleotide-excision repair [PMID:8910442]
experiment: EXISTENCE:direct assay:GO:0030491 heteroduplex formation [PMID:12226081]
experiment: EXISTENCE:direct assay:GO:0032079 positive regulation of endodeoxyribonuclease activity [PMID:34764291]
experiment: EXISTENCE:direct assay:GO:0043565 sequence-specific DNA binding [PMID:7761422]
experiment: EXISTENCE:genetic interaction:GO:0000722 telomere maintenance via recombination [PMID:17202155]
experiment: EXISTENCE:genetic interaction:GO:0000724 double-strand break repair via homologous recombination [PMID:9679065]
experiment: EXISTENCE:mutant phenotype:GO:0000781 chromosome, telomeric region [PMID:14702040]
experiment: EXISTENCE:mutant phenotype:GO:0006260 DNA replication [PMID:7969128]
experiment: EXISTENCE:mutant phenotype:GO:0006281 DNA repair [PMID:7969128]
experiment: EXISTENCE:mutant phenotype:GO:0006312 mitotic recombination [PMID:7969128]
experiment: EXISTENCE:mutant phenotype:GO:0007131 reciprocal meiotic recombination [PMID:12072452]
experiment: EXISTENCE:mutant phenotype:GO:0010833 telomere maintenance via telomere lengthening [PMID:22354040]
experiment: EXISTENCE:mutant phenotype:GO:0016567 protein ubiquitination [PMID:18342608]
experiment: EXISTENCE:mutant phenotype:GO:0032079 positive regulation of endodeoxyribonuclease activity [PMID:34764291]
experiment: EXISTENCE:mutant phenotype:GO:1905776 positive regulation of DNA helicase activity [PMID:34764291]
experiment: EXISTENCE:physical interaction:GO:0007004 telomere maintenance via telomerase [PMID:2554144]
experiment: EXISTENCE:physical interaction:GO:0016567 protein ubiquitination [PMID:18342608]
experiment: EXISTENCE:physical interaction:GO:0045184 establishment of protein localization [PMID:2554144]
note: Subunit of heterotrimeric Replication Protein A (RPA); RPA is a highly conserved ssDNA binding protein involved in DNA replication, repair, and recombination; RPA protects against inappropriate telomere recombination, and upon telomere uncapping, prevents cell proliferation by a checkpoint-independent pathway; promotes recruitment, helicase and nuclease activities of Dna2p; role in DNA catenation/decatenation pathway of chromosome disentangling; relocalizes to the cytosol in response to hypoxia
codon start: 1
product: replication factor A subunit protein RFA1
translation: MSSVQLSRGDFHSIFTNKQRYDNPTGGVYQVYNTRKSDGANSNRKNLIMISDGIYHMKALLRNQAASKFQSMELQRGDIIRVIIAEPAIVRERKKYVLLVDDFELVQSRADMVNQTSTFLDNYFSEHPNETLKDEDITDSGNVANQTNASNAGVPDMLHSNSNLNANERKFANENPNSQKTRPIFAIEQLSPYQNVWTIKARVSYKGEIKTWHNQRGDGKLFNVNFLDTSGEIRATAFNDFATKFNEILQEGKVYYVSKAKLQPAKPQFTNLTHPYELNLDRDTVIEECFDESNVPKTHFNFIKLDAIQNQEVNSNVDVLGIIQTINPHFELTSRAGKKFDRRDITIVDDSGFSISVGLWNQQALDFNLPEGSVAAIKGVRVTDFGGKSLSMGFSSTLIPNPEIPEAYALKGWYDSKGRNANFITLKQEPGMGGQSAASLTKFIAQRITIARAQAENLGRSEKGDFFSVKAAISFLKVDNFAYPACSNENCNKKVLEQPDGTWRCEKCDTNNARPNWRYILTISIIDETNQLWLTLFDDQAKQLLGVDANTLMSLKEEDPNEFTKITQSIQMNEYDFRIRAREDTYNDQSRIRYTVANLHSLNYRAEADYLADELSKALLA
SIO_010081: YAR007C
subclass of: SO_0000673
so part of: YAR007C
location: complement(156754..158619)
location: region:156754-158619:-1
so has part: feature:156754-158619:-1:exon

NP_009404.1
type: Protein
SIO_000068: ncbiprotein

S000000065
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:156754-158619:-1:exon

YAR008W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: FUN4
gene: SEN34
locus tag: YAR008W
gene synonym: FUN4
so part of: sequence
location: <158966..>159793
location: region:158966-159793:1
so has part: feature:158966-159793:1:exon
subclass of: SO_0000010

851267
type: Gene
SIO_000068: ncbigene

position:158966:1
position: 158966
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:159793:1
position: 159793
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:158966-159793:1:exon

YAR008W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: FUN4
gene: SEN34
locus tag: YAR008W
gene synonym: FUN4
product: tRNA splicing endonuclease subunit SEN34
transcript id: NM_001178212.1
SIO_010081: YAR008W
subclass of: SO_0000673
so part of: YAR008W
location: <158966..>159793
location: region:158966-159793:1
so has part: feature:158966-159793:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:158966-159793:1:exon

YAR008W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: FUN4
gene: SEN34
locus tag: YAR008W
gene synonym: FUN4
EC number: 4.6.1.16
experiment: EXISTENCE:direct assay:GO:0000213 tRNA-intron endonuclease activity [PMID:9200603]
experiment: EXISTENCE:direct assay:GO:0000214 tRNA-intron endonuclease complex [PMID:9200603]
experiment: EXISTENCE:direct assay:GO:0000379 tRNA-type intron splice site recognition and cleavage [PMID:9200603]
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:16823961]
experiment: EXISTENCE:direct assay:GO:0005741 mitochondrial outer membrane [PMID:16407407]
experiment: EXISTENCE:mutant phenotype:GO:0000213 tRNA-intron endonuclease activity [PMID:9200603]
experiment: EXISTENCE:mutant phenotype:GO:0000379 tRNA-type intron splice site recognition and cleavage [PMID:9200603]
note: Subunit of the tRNA splicing endonuclease; tRNA splicing endonuclease (Sen complex) is composed of Sen2p, Sen15p, Sen34p, and Sen54p; Sen complex also cleaves the CBP1 mRNA at the mitochondrial surface; Sen34p contains the active site for tRNA 3' splice site cleavage and has similarity to Sen2p and to Archaeal tRNA splicing endonuclease
codon start: 1
product: tRNA splicing endonuclease subunit SEN34
translation: MPPLVFDIDHIKLLRKWGICGVLSGTLPTAAQQNVFLSVPLRLMLEDVLWLHLNNLADVKLIRQEGDEIMEGITLERGAKLSKIVNDRLNKSFEYQRKFKKDEHIAKLKKIGRINDKTTAEELQRLDKSSNNDQLIESSLFIDIANTSMILRDIRSDSDSLSRDDISDLLFKQYRQAGKMQTYFLYKALRDQGYVLSPGGRFGGKFIAYPGDPLRFHSHLTIQDAIDYHNEPIDLISMISGARLGTTVKKLWVIGGVAEETKETHFFSIEWAGFG
SIO_010081: YAR008W
subclass of: SO_0000673
so part of: YAR008W
location: 158966..159793
location: region:158966-159793:1
so has part: feature:158966-159793:1:exon

NP_009405.1
type: Protein
SIO_000068: ncbiprotein

S000000066
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:158966-159793:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS101; ARS containing multiple redundant ORC binding sites; ORC is the acronym for origin recognition complex
so part of: sequence
location: 159907..160127
location: region:159907-160127:1
so has part: feature:159907-160127:1:region

S000077372
type: SGD
SIO_000068: sgd

position:159907:1
position: 159907
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:160127:1
position: 160127
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:159907-160127:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(160105..160237)
location: region:160105-160237:-1
so has part: feature:160105-160237:-1:region

S000006788
type: SGD
SIO_000068: sgd

position:160105:-1
position: 160105
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:160237:-1
position: 160237
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:160105-160237:-1:region

mobile_element
type: Mobile Element
subclass of: SO_0001037
RO_0002162: 559292
note: YARCTy1-1; Ty1 element, LTR retrotransposon of the Copia (Pseudoviridae) group; contains genes TYA Gag and TYB Pol, encoding proteins involved in structure and function of virus-like particles, flanked by two direct repeats; mutated in S288C
mobile element type: retrotransposon:YARCTy1-1
so part of: sequence
location: complement(160238..166162)
location: region:160238-166162:-1
so has part: feature:160238-166162:-1:region

S000006792
type: SGD
SIO_000068: sgd

position:160238:-1
position: 160238
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:166162:-1
position: 166162
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:160238-166162:-1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(160238..160574)
location: region:160238-160574:-1
so has part: feature:160238-160574:-1:region

S000006789
type: SGD
SIO_000068: sgd

position:160574:-1
position: 160574
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:160238-160574:-1:region

YAR009C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YAR009C
so part of: sequence
location: complement(<160597..>164187)
location: region:160597-164187:-1
so has part: feature:160597-164187:-1:exon
subclass of: SO_0000010

851268
type: Gene
SIO_000068: ncbigene

position:160597:-1
position: 160597
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:164187:-1
position: 164187
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:160597-164187:-1:exon

YAR009C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YAR009C
product: truncated gag-pol fusion protein
transcript id: NM_001178213.1
SIO_010081: YAR009C
subclass of: SO_0000673
so part of: YAR009C
location: complement(<160597..>164187)
location: region:160597-164187:-1
so has part: feature:160597-164187:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:160597-164187:-1:exon

YAR009C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YAR009C
EC number: 2.7.7.7
EC number: 2.7.7.49
EC number: 3.1.26.4
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:9448009]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22842922]
note: Retrotransposon TYA Gag and TYB Pol genes; Gag processing produces capsid proteins, Pol is cleaved to produce protease, reverse transcriptase and integrase activities; in YARCTy1-1 TYB is mutant and probably non-functional; protein product forms cytoplasmic foci upon DNA replication stress
codon start: 1
product: truncated gag-pol fusion protein
translation: METFTGYLKSTCFHQISPYPPSIMSIQVKVHANILILSFIECLRMPMHRQIRYSLKNNTITYFNESDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKSAPSYFISFTDETTKLRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSEYTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFSAIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLTASYHSFIASNEIQESNDLNIESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTEDSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISNIESTGSGGMHKLNVPLLAPMSQSNTHESSHASKSKDFRHSDSYSENETNHTNVPISSTGGTNNKTVPQISDQETEKRIIHRSPSIDASPPENNSSHNIVPIKTPTTVSEQNTEESIIADLPLPDLPPESPTEFPDPFKELPPINSHQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSLEPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLLKMNTWDTDKYYDRKEIDPKRVINSMFIFNKKRDGTHKARFVARGDIQHPDTYDTGMQSNTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLKKSLYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRGKYMKLGMEKSLTEKLPKLNVPLNPKGKKLRAPGQPGLYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTEPDNKLVAISDASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSYLIQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYYIETKKNIADVMTKPLPIKTFKLLTNKWIH
SIO_010081: YAR009C
subclass of: SO_0000673
so part of: YAR009C
location: complement(160597..164187)
location: region:160597-164187:-1
so has part: feature:160597-164187:-1:exon

NP_009406.1
type: Protein
SIO_000068: ncbiprotein

S000000067
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:160597-164187:-1:exon

YAR010C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YAR010C
so part of: sequence
location: complement(<164544..>165866)
location: region:164544-165866:-1
so has part: feature:164544-165866:-1:exon
subclass of: SO_0000010

851269
type: Gene
SIO_000068: ncbigene

position:164544:-1
position: 164544
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:165866:-1
position: 165866
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:164544-165866:-1:exon

YAR010C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YAR010C
product: gag protein
transcript id: NM_001178214.1
SIO_010081: YAR010C
subclass of: SO_0000673
so part of: YAR010C
location: complement(<164544..>165866)
location: region:164544-165866:-1
so has part: feature:164544-165866:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:164544-165866:-1:exon

YAR010C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YAR010C
note: Retrotransposon TYA Gag gene co-transcribed with TYB Pol; Gag processing produces capsid proteins; in YARCTy1-1 TYB is mutant and probably non-functional
codon start: 1
product: gag protein
translation: MESQQLSQHSPISHGSACASVTSKEVHTNQDPLDVSASKTEECEKASTKANSQQTTTPASSAVPENPHHASPQTAQSHSPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPETY
SIO_010081: YAR010C
subclass of: SO_0000673
so part of: YAR010C
location: complement(164544..165866)
location: region:164544-165866:-1
so has part: feature:164544-165866:-1:exon

NP_009407.1
type: Protein
SIO_000068: ncbiprotein

S000000068
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:164544-165866:-1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(165826..166162)
location: region:165826-166162:-1
so has part: feature:165826-166162:-1:region

S000006790
type: SGD
SIO_000068: sgd

position:165826:-1
position: 165826
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:165826-166162:-1:region

YNCA0004W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: TGA1
locus tag: YNCA0004W
so part of: sequence
location: 166267..166339
location: region:166267-166339:1
so has part: feature:166267-166339:1:exon
subclass of: SO_0000663

851270
type: Gene
SIO_000068: ncbigene

position:166267:1
position: 166267
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:166339:1
position: 166339
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:166267-166339:1:exon

YNCA0004W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
gene: TGA1
locus tag: YNCA0004W
product: tRNA-Ala
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Alanine tRNA (tRNA-Ala), predicted by tRNAscan-SE analysis; one of 5 nuclear tRNA genes containing the tDNA-anticodon TGC (mature tRNA may be UGC or may contain modified bases), decodes GCA and probably GCG codons into alanine, one of 16 nuclear tRNAs for alanine
SIO_010081: YNCA0004W
subclass of: SO_0000673
so part of: YNCA0004W
location: 166267..166339
location: region:166267-166339:1
so has part: feature:166267-166339:1:exon

S000006521
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:166267-166339:1:exon

YAR014C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: BUD14
locus tag: YAR014C
so part of: sequence
location: complement(<166742..>168871)
location: region:166742-168871:-1
so has part: feature:166742-168871:-1:exon
subclass of: SO_0000010

851271
type: Gene
SIO_000068: ncbigene

position:166742:-1
position: 166742
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:168871:-1
position: 168871
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:166742-168871:-1:exon

YAR014C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: BUD14
locus tag: YAR014C
product: protein phosphatase regulator BUD14
transcript id: NM_001178215.2
SIO_010081: YAR014C
subclass of: SO_0000673
so part of: YAR014C
location: complement(<166742..>168871)
location: region:166742-168871:-1
so has part: feature:166742-168871:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:166742-168871:-1:exon

YAR014C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: BUD14
locus tag: YAR014C
experiment: EXISTENCE:direct assay:GO:0000131 incipient cellular bud site [PMID:11452010]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005934 cellular bud tip [PMID:11452010]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:11452010]
experiment: EXISTENCE:direct assay:GO:0006355 regulation of DNA-templated transcription [PMID:15601868]
experiment: EXISTENCE:direct assay:GO:0019888 protein phosphatase regulator activity [PMID:16107882]
experiment: EXISTENCE:direct assay:GO:0030837 negative regulation of actin filament polymerization [PMID:19217430]
experiment: EXISTENCE:direct assay:GO:0032880 regulation of protein localization [PMID:19217430]
experiment: EXISTENCE:direct assay:GO:1990615 Kelch-containing formin regulatory complex [PMID:24828508]
experiment: EXISTENCE:genetic interaction:GO:0008360 regulation of cell shape [PMID:12477789]
experiment: EXISTENCE:genetic interaction:GO:0030837 negative regulation of actin filament polymerization [PMID:19217430]
experiment: EXISTENCE:genetic interaction:GO:0032465 regulation of cytokinesis [PMID:24828508]
experiment: EXISTENCE:genetic interaction:GO:0090337 regulation of formin-nucleated actin cable assembly [PMID:24828508]
experiment: EXISTENCE:mutant phenotype:GO:0001100 negative regulation of exit from mitosis [PMID:34633288]
experiment: EXISTENCE:mutant phenotype:GO:0006355 regulation of DNA-templated transcription [PMID:15601868]
experiment: EXISTENCE:mutant phenotype:GO:0007010 cytoskeleton organization [PMID:16107882]
experiment: EXISTENCE:mutant phenotype:GO:0019888 protein phosphatase regulator activity [PMID:16107882]
experiment: EXISTENCE:mutant phenotype:GO:0030837 negative regulation of actin filament polymerization [PMID:19217430]
experiment: EXISTENCE:mutant phenotype:GO:0060627 regulation of vesicle-mediated transport [PMID:24828508]
note: Protein involved in bud-site selection; Bud14p-Glc7p complex is a cortical regulator of dynein; forms a complex with Kel1p and Kel2p that regulates Bnr1p (formin) to affect actin cable assembly, cytokinesis, and polarized growth; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern; relative distribution to the nucleus increases upon DNA replication stress
codon start: 1
product: protein phosphatase regulator BUD14
translation: MSNKEEHVDETSASGVKEVSSIAARHDNGYAPSLITSTSGMDSFQSHALLNDPTLIEDYSDIINNRPTSGSKLTLGNEDSESMGGSVVVTPTSNKSSPFNSKLNILSNAAEKGHDVLRNRDDDKELEEENVEKHMHSNSKRDQRHYKENSSELPDSYDYSDSEFEDNLERRLQEIETDSVDSADKDEVHFSVNNTMNPDVDDFSDGLKYAISEDEDEEENYSDDDDFDRKFQDSGFQGEKDDLEEENDDYQPLSPPRELDPDKLYALYAFNGHDSSHCQLGQDEPCILLNDQDAYWWLVKRITDGKIGFAPAEILETFPERLARLNCWKNENMSSQSVASSDSKDDSISSGNKNQSDAESIIPTPALNGYGKGNKSVSFNDVVGYADRFIDDAIEDTSLDSNDDGGEGNGQSYDDDVDNDKETKVTHRDEYTEAKLNFGKFQDDDTSDVVSDVSFSTSLNTPLNVKKVRRQDNKNESEPKTSSSKDREDDYNANRYVGQEKSEPVDSDYDTDLKKVFEAPRMPFANGMAKSDSQNSLSTIGEFSPSSSEWTNESPSTPIVEESSSIPSSRAIKDISQYIHAKSKIEETTNVENTEGQIQASLGSSGGMANQTDAEQPKEELEKHHSTPEEEKQSTLSLHSSSEEDFYMDEQRAVSSASINSSLSGSRALSNTNMSDPASKPNSLVQHLYAPVFDRMDVLMKQLDEIIRK
SIO_010081: YAR014C
subclass of: SO_0000673
so part of: YAR014C
location: complement(166742..168871)
location: region:166742-168871:-1
so has part: feature:166742-168871:-1:exon

NP_009408.3
type: Protein
SIO_000068: ncbiprotein

S000000069
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:166742-168871:-1:exon

YAR015W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: ADE1
locus tag: YAR015W
so part of: sequence
location: <169375..>170295
location: region:169375-170295:1
so has part: feature:169375-170295:1:exon
subclass of: SO_0000010

851272
type: Gene
SIO_000068: ncbigene

position:169375:1
position: 169375
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:170295:1
position: 170295
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:169375-170295:1:exon

YAR015W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: ADE1
locus tag: YAR015W
product: phosphoribosylaminoimidazolesuccinocarboxamide synthase
transcript id: NM_001178216.1
SIO_010081: YAR015W
subclass of: SO_0000673
so part of: YAR015W
location: <169375..>170295
location: region:169375-170295:1
so has part: feature:169375-170295:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:169375-170295:1:exon

YAR015W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: ADE1
locus tag: YAR015W
EC number: 6.3.2.6
experiment: EXISTENCE:direct assay:GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity [PMID:1756975]
experiment: EXISTENCE:direct assay:GO:0005634 nucleus [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:14562095]
experiment: EXISTENCE:direct assay:GO:0006164 purine nucleotide biosynthetic process [PMID:1756975]
experiment: EXISTENCE:direct assay:GO:0006189 'de novo' IMP biosynthetic process [PMID:1756975]
experiment: EXISTENCE:mutant phenotype:GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity [PMID:5767024|PMID:5767025]
experiment: EXISTENCE:mutant phenotype:GO:0006164 purine nucleotide biosynthetic process [PMID:5767025|PMID:5767024]
experiment: EXISTENCE:mutant phenotype:GO:0006189 'de novo' IMP biosynthetic process [PMID:5767024|PMID:5767025]
note: N-succinyl-5-aminoimidazole-4-carboxamide ribotide synthetase; required for 'de novo' purine nucleotide biosynthesis; red pigment accumulates in mutant cells deprived of adenine; protein abundance increases in response to DNA replication stress
codon start: 1
product: phosphoribosylaminoimidazolesuccinocarboxamide synthase
translation: MSITKTELDGILPLVARGKVRDIYEVDAGTLLFVATDRISAYDVIMENSIPEKGILLTKLSEFWFKFLSNDVRNHLVDIAPGKTIFDYLPAKLSEPKYKTQLEDRSLLVHKHKLIPLEVIVRGYITGSAWKEYVKTGTVHGLKQPQGLKESQEFPEPIFTPSTKAEQGEHDENISPAQAAELVGEDLSRRVAELAVKLYSKCKDYAKEKGIIIADTKFEFGIDEKTNEIILVDEVLTPDSSRFWNGASYKVGESQDSYDKQFLRDWLTANKLNGVNGVKMPQDIVDRTRAKYIEAYETLTGSKWSH
SIO_010081: YAR015W
subclass of: SO_0000673
so part of: YAR015W
location: 169375..170295
location: region:169375-170295:1
so has part: feature:169375-170295:1:exon

NP_009409.1
type: Protein
SIO_000068: ncbiprotein

S000000070
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:169375-170295:1:exon

YAR018C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: FUN52
alternative label: NPK1
gene: KIN3
locus tag: YAR018C
gene synonym: FUN52; NPK1
so part of: sequence
location: complement(<170396..>171703)
location: region:170396-171703:-1
so has part: feature:170396-171703:-1:exon
subclass of: SO_0000010

851273
type: Gene
SIO_000068: ncbigene

position:170396:-1
position: 170396
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:171703:-1
position: 171703
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:170396-171703:-1:exon

YAR018C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: FUN52
alternative label: NPK1
gene: KIN3
locus tag: YAR018C
gene synonym: FUN52; NPK1
product: serine/threonine protein kinase KIN3
transcript id: NM_001178217.1
SIO_010081: YAR018C
subclass of: SO_0000673
so part of: YAR018C
location: complement(<170396..>171703)
location: region:170396-171703:-1
so has part: feature:170396-171703:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:170396-171703:-1:exon

YAR018C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: FUN52
alternative label: NPK1
gene: KIN3
locus tag: YAR018C
gene synonym: FUN52; NPK1
EC number: 2.7.11.1
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:16319894]
experiment: EXISTENCE:direct assay:GO:0006468 protein phosphorylation [PMID:16319894]
experiment: EXISTENCE:mutant phenotype:GO:0007059 chromosome segregation [PMID:12386167]
note: Nonessential serine/threonine protein kinase; possible role in DNA damage response; influences tolerance to high levels of ethanol
codon start: 1
product: serine/threonine protein kinase KIN3
translation: MHRRQFFQEYRSPQQQQGHPPRSEYQVLEEIGRGSFGSVRKVIHIPTKKLLVRKDIKYGHMNSKERQQLIAECSILSQLKHENIVEFYNWDFDEQKEVLYLYMEYCSRGDLSQMIKHYKQEHKYIPEKIVWGILAQLLTALYKCHYGVELPTLTTIYDRMKPPVKGKNIVIHRDLKPGNIFLSYDDSDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQVVVKLGDFGLAKSLETSIQFATTYVGTPYYMSPEVLMDQPYSPLSDIWSLGCVIFEMCSLHPPFQAKNYLELQTKIKNGKCDTVPEYYSRGLNAIIHSMIDVNLRTRPSTFELLQDIQIRTARKSLQLERFERKLLDYENELTNIEKILEKQAIEYERELSQLKEQFTQAVEERAREVISGKKVGKVPESINGYYGKKFAKPAYHWQTRYR
SIO_010081: YAR018C
subclass of: SO_0000673
so part of: YAR018C
location: complement(170396..171703)
location: region:170396-171703:-1
so has part: feature:170396-171703:-1:exon

NP_009410.1
type: Protein
SIO_000068: ncbiprotein

S000000071
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:170396-171703:-1:exon

YAR019C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: LYT1
alternative label: RLT1
gene: CDC15
locus tag: YAR019C
gene synonym: LYT1; RLT1
so part of: sequence
location: complement(<172211..>175135)
location: region:172211-175135:-1
so has part: feature:172211-175135:-1:exon
subclass of: SO_0000010

851274
type: Gene
SIO_000068: ncbigene

position:172211:-1
position: 172211
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:175135:-1
position: 175135
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:172211-175135:-1:exon

YAR019C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: LYT1
alternative label: RLT1
gene: CDC15
locus tag: YAR019C
gene synonym: LYT1; RLT1
product: serine/threonine protein kinase CDC15
transcript id: NM_001178218.2
SIO_010081: YAR019C
subclass of: SO_0000673
so part of: YAR019C
location: complement(<172211..>175135)
location: region:172211-175135:-1
so has part: feature:172211-175135:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:172211-175135:-1:exon

YAR019C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: LYT1
alternative label: RLT1
gene: CDC15
locus tag: YAR019C
gene synonym: LYT1; RLT1
EC number: 2.7.11.1
experiment: EXISTENCE:direct assay:GO:0004672 protein kinase activity [PMID:16319894]
experiment: EXISTENCE:direct assay:GO:0004674 protein serine/threonine kinase activity [PMID:11404483|PMID:23579499]
experiment: EXISTENCE:direct assay:GO:0005737 cytoplasm [PMID:22842922]
experiment: EXISTENCE:direct assay:GO:0005816 spindle pole body [PMID:10662594|PMID:12832486]
experiment: EXISTENCE:direct assay:GO:0005935 cellular bud neck [PMID:12832486]
experiment: EXISTENCE:genetic interaction:GO:1903024 positive regulation of ascospore-type prospore membrane formation [PMID:32788308]
experiment: EXISTENCE:mutant phenotype:GO:0000281 mitotic cytokinesis [PMID:11267871]
experiment: EXISTENCE:mutant phenotype:GO:0004674 protein serine/threonine kinase activity [PMID:23579499]
experiment: EXISTENCE:mutant phenotype:GO:0007096 regulation of exit from mitosis [PMID:11267871]
experiment: EXISTENCE:mutant phenotype:GO:0051229 meiotic spindle disassembly [PMID:17660551|PMID:32788308]
experiment: EXISTENCE:mutant phenotype:GO:1903024 positive regulation of ascospore-type prospore membrane formation [PMID:32788308]
experiment: EXISTENCE:mutant phenotype:GO:1904750 negative regulation of protein localization to nucleolus [PMID:32788308]
note: Hippo-like kinase of the Mitotic Exit Network; promotes exit by activating the Dbf2p kinase; component of a non-canonical Hippo pathway with Sps1p required for prospore membrane closure, spindle disassembly and sustained release of Cdc14p during meiotic anaphase II; complexes with Sps1p and contributes to its phosphorylation; phosphorylates the RNAPII CTD during mitosis; localizes to the bud neck and SPB during anaphase and telophase; relocalizes to the cytoplasm upon DNA replication stress
codon start: 1
product: serine/threonine protein kinase CDC15
translation: MNSMADTDRVNLTPIQRASEKSVQYHLKQVIGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVNSSALTLAGTLNWMAPEILGNRGASTLSDIWSLGATVVEMLTKNPPYHNLTDANIYYAVENDTYYPPSSFSEPLKDFLSKCFVKNMYKRPTADQLLKHVWINSTENVKVDKLNKFKEDFTDADYHWDADFQEEKLNISPSKFSLAAAPAAWAENNQELDLMPPTESQLLSQLKSSSKPLTDLHVLFSVCSLENIADTIIECLSRTTVDKRLITAFGSIFVYDTQHNHSRLRLKFIAMGGIPLIIKFEHLAKEFVIDYPQTLIECGIMYPPNFASLKTPKYILELVYRFYDLTSTAFWCRWCFKHLDISLLLNNIHERRAQSILLKLSSYAPWSFEKILPSLIDSKLKKKILISPQITYVVFKSINYMITTNDDKIHKSAIPSSSSLPLSSSPTRNSPVNSVQSPSRSPVHSLMATRPSSPMRHKSISNFPHLTISSKSRLLIELPEGFFTWLTSFFVDMAQIKDLSVLKYFTKLCYLTVHINSTFLNDLLDNDAFFAFIRNIDTIIPFIDDAKTAAFIWKQITAICVEMSLDMDQMSASLFSTAMNFIRKKNNTSISGLEIILNCLHFTLRNVNDDVAPTVGSSESHSVFLIKVNNDAAIELPIDQLVDLFYALNDDDVNLSKLISIFTKICSLPGFENLTINIIFHPNFYEKIVSFFDTYFNSLLIQIDLLKFIKLIFSKSLLKLYDYTGQPDPIKQTEPNRRNKATVFKLRAILVQITEFLNNNWNKDVPKRNSNQVGGDSVLICQLCEDIRSLSKKGSLQKVSSVTAAIGSSPTKDERSNLRSSKDKSDGFSVPITTFQT
SIO_010081: YAR019C
subclass of: SO_0000673
so part of: YAR019C
location: complement(172211..175135)
location: region:172211-175135:-1
so has part: feature:172211-175135:-1:exon

NP_009411.2
type: Protein
SIO_000068: ncbiprotein

S000000072
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:172211-175135:-1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS110; Autonomously Replicating Sequence; originally referred to as ADE1 ARS
so part of: sequence
location: 176157..176404
location: region:176157-176404:1
so has part: feature:176157-176404:1:region

S000114488
type: SGD
SIO_000068: sgd

position:176157:1
position: 176157
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:176404:1
position: 176404
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:176157-176404:1:region

YAR020C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PAU7
locus tag: YAR020C
so part of: sequence
location: complement(<176856..>177023)
location: region:176856-177023:-1
so has part: feature:176856-177023:-1:exon
subclass of: SO_0000010

851275
type: Gene
SIO_000068: ncbigene

position:176856:-1
position: 176856
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:177023:-1
position: 177023
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:176856-177023:-1:exon

YAR020C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PAU7
locus tag: YAR020C
product: seripauperin PAU7
transcript id: NM_001178219.1
SIO_010081: YAR020C
subclass of: SO_0000673
so part of: YAR020C
location: complement(<176856..>177023)
location: region:176856-177023:-1
so has part: feature:176856-177023:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:176856-177023:-1:exon

YAR020C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PAU7
locus tag: YAR020C
note: Member of the seripauperin multigene family; active during alcoholic fermentation, regulated by anaerobiosis, inhibited by oxygen, repressed by heme
codon start: 1
product: seripauperin PAU7
translation: MVKLTSIAAGVAAIAAGASAAATTTLSQSDERVNLVELGVYVSDIRAHLAEYYSF
SIO_010081: YAR020C
subclass of: SO_0000673
so part of: YAR020C
location: complement(176856..177023)
location: region:176856-177023:-1
so has part: feature:176856-177023:-1:exon

NP_009412.1
type: Protein
SIO_000068: ncbiprotein

S000000073
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:176856-177023:-1:exon

YAR023C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YAR023C
so part of: sequence
location: complement(<179281..>179820)
location: region:179281-179820:-1
so has part: feature:179281-179820:-1:exon
subclass of: SO_0000010

851276
type: Gene
SIO_000068: ncbigene

position:179281:-1
position: 179281
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:179820:-1
position: 179820
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:179281-179820:-1:exon

YAR023C
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YAR023C
product: DUP240 family protein
transcript id: NM_001178220.2
SIO_010081: YAR023C
subclass of: SO_0000673
so part of: YAR023C
location: complement(<179281..>179820)
location: region:179281-179820:-1
so has part: feature:179281-179820:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:179281-179820:-1:exon

YAR023C
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YAR023C
note: Putative integral membrane protein; member of DUP240 gene family
codon start: 1
product: DUP240 family protein
translation: MINFLLFVLTILATLTNIWFSGVLSPAMVIRICLGGSMVVLQIWSFSRPISNETFRTKLLLEVITHRPSIAGKEWKTITYNMNQYLFKAGLWKTPYHFFCEHQCYEFFKDLIKGKYPDVQWDTANTQPFISVPENQAATQNSDVEPTVKWCLFKAAEIQAHAVREYWQSQYPDVGIPAI
SIO_010081: YAR023C
subclass of: SO_0000673
so part of: YAR023C
location: complement(179281..179820)
location: region:179281-179820:-1
so has part: feature:179281-179820:-1:exon

NP_009413.2
type: Protein
SIO_000068: ncbiprotein

S000000074
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:179281-179820:-1:exon

YNCA0005W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: SUP56
locus tag: YNCA0005W
so part of: sequence
location: 181141..181254
location: region:181141-181254:1
so has part: feature:181141-181254:1:exon
subclass of: SO_0000663

851277
type: Gene
SIO_000068: ncbigene

position:181141:1
position: 181141
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:181254:1
position: 181254
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:181141-181254:1:exon

YNCA0005W
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
gene: SUP56
locus tag: YNCA0005W
product: tRNA-Leu
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
note: Leucine tRNA (tRNA-Leu), predicted by tRNAscan-SE analysis; can mutate to suppress amber nonsense mutations
SIO_010081: YNCA0005W
subclass of: SO_0000673
so part of: YNCA0005W
location: join(181141..181178,181211..181254)
location: region:181141-181254:1
so has part: feature:181141-181178:1:exon
so has part: feature:181211-181254:1:exon

S000006636
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:181141-181178:1:exon

position:181178:1
position: 181178
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:181211-181254:1:exon

position:181211:1
position: 181211
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

YNCA0006C
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YNCA0006C
so part of: sequence
location: complement(182522..182603)
location: region:182522-182603:-1
so has part: feature:182522-182603:-1:exon
subclass of: SO_0000663

851278
type: Gene
SIO_000068: ncbigene

position:182522:-1
position: 182522
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:182603:-1
position: 182603
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:182522-182603:-1:exon

YNCA0006C
type: Transfer RNA
subclass of: SO_0000253
RO_0002162: 559292
locus tag: YNCA0006C
product: tRNA-Ser
experiment: EXISTENCE:curator inference:GO:0005829 cytosol [PMID:9023104]
experiment: EXISTENCE:curator inference:GO:0006414 translational elongation [PMID:9023104]
experiment: EXISTENCE:direct assay:GO:0030371 translation repressor activity [PMID:27609601]
experiment: EXISTENCE:direct assay:GO:0043022 ribosome binding [PMID:27609601]
experiment: EXISTENCE:direct assay:GO:0043555 regulation of translation in response to stress [PMID:27609601]
note: Serine tRNA (tRNA-Ser), predicted by tRNAscan-SE analysis
SIO_010081: YNCA0006C
subclass of: SO_0000673
so part of: YNCA0006C
location: complement(182522..182603)
location: region:182522-182603:-1
so has part: feature:182522-182603:-1:exon

S000006719
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:182522-182603:-1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty3 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 182620..182959
location: region:182620-182959:1
so has part: feature:182620-182959:1:region

S000006795
type: SGD
SIO_000068: sgd

position:182620:1
position: 182620
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:182959:1
position: 182959
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:182620-182959:1:region

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 183142..183474
location: region:183142-183474:1
so has part: feature:183142-183474:1:region

S000006793
type: SGD
SIO_000068: sgd

position:183142:1
position: 183142
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:183474:1
position: 183474
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:183142-183474:1:region

YAR027W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: UIP3
locus tag: YAR027W
so part of: sequence
location: <183770..>184477
location: region:183770-184477:1
so has part: feature:183770-184477:1:exon
subclass of: SO_0000010

851279
type: Gene
SIO_000068: ncbigene

position:183770:1
position: 183770
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:184477:1
position: 184477
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:183770-184477:1:exon

YAR027W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: UIP3
locus tag: YAR027W
product: DUP240 family protein UIP3
transcript id: NM_001178221.1
SIO_010081: YAR027W
subclass of: SO_0000673
so part of: YAR027W
location: <183770..>184477
location: region:183770-184477:1
so has part: feature:183770-184477:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:183770-184477:1:exon

YAR027W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: UIP3
locus tag: YAR027W
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005635 nuclear envelope [PMID:11056382]
note: Putative integral membrane hypothetical protein; interacts with Ulp1p at the nuclear periphery; member of DUP240 gene family
codon start: 1
product: DUP240 family protein UIP3
translation: MQTPSENTDVKLDTLDEPSAHLIEENVALPEDTFNSYWSYILNEIARCKPLMIMFLIPVCLVLLITFFHDIKGILVFLVISLILSIIILLIGITAFVSETLNKGFIIKLLVEVITRKPAVGGKEWRIIAYNMNQYLFDHGIWHTPYYFFCEHRCHKFFKSLIKQTRSNAHLSSPTNGAENTQSNTPAKEVSNEMVKPYIFSSDPVLEAYLIKAAEIHKEAEFEYWRKQYPEVDLP
SIO_010081: YAR027W
subclass of: SO_0000673
so part of: YAR027W
location: 183770..184477
location: region:183770-184477:1
so has part: feature:183770-184477:1:exon

NP_009414.1
type: Protein
SIO_000068: ncbiprotein

S000000075
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:183770-184477:1:exon

YAR028W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YAR028W
so part of: sequence
location: <184892..>185596
location: region:184892-185596:1
so has part: feature:184892-185596:1:exon
subclass of: SO_0000010

851280
type: Gene
SIO_000068: ncbigene

position:184892:1
position: 184892
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:185596:1
position: 185596
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:184892-185596:1:exon

YAR028W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YAR028W
product: DUP240 family protein
transcript id: NM_001178222.1
SIO_010081: YAR028W
subclass of: SO_0000673
so part of: YAR028W
location: <184892..>185596
location: region:184892-185596:1
so has part: feature:184892-185596:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:184892-185596:1:exon

YAR028W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YAR028W
experiment: EXISTENCE:direct assay:GO:0000329 fungal-type vacuole membrane [PMID:19001347|PMID:26928762]
note: Putative integral membrane protein; member of DUP240 gene family; GFP-fusion protein is induced in response to the DNA-damaging agent MMS
codon start: 1
product: DUP240 family protein
translation: MQTPSENTDVKMDTLDEPSAHLIEENVALPEDTFSSHLSYVLYEIAHCKPIMFMIIIIVSLISLIVLFHDNDGCTVILVMSLIVASMALMVVAAFTFGKAITEQEFMIKLLVEVIARKPAGKEWGTVAYNMNQYLFMKRLWYTPYYFYSGKKCHEFFTTLIKEVNSGSHSDSSSNSAEDTQSPVSAGKTSNGLNNFYSIRSDPILMAYVLKATQIEKEAQSEYWRKQYPDADLP
SIO_010081: YAR028W
subclass of: SO_0000673
so part of: YAR028W
location: 184892..185596
location: region:184892-185596:1
so has part: feature:184892-185596:1:exon

NP_009415.1
type: Protein
SIO_000068: ncbiprotein

S000000076
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:184892-185596:1:exon

YAR029W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YAR029W
so part of: sequence
location: <186321..>186545
location: region:186321-186545:1
so has part: feature:186321-186545:1:exon
subclass of: SO_0000010

851281
type: Gene
SIO_000068: ncbigene

position:186321:1
position: 186321
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:186545:1
position: 186545
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:186321-186545:1:exon

YAR029W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YAR029W
product: DUP240 family protein
transcript id: NM_001178223.1
SIO_010081: YAR029W
subclass of: SO_0000673
so part of: YAR029W
location: <186321..>186545
location: region:186321-186545:1
so has part: feature:186321-186545:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:186321-186545:1:exon

YAR029W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YAR029W
experiment: EXISTENCE:mutant phenotype:GO:0005737 cytoplasm [PMID:12101299]
note: Member of DUP240 gene family but contains no transmembrane domains; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
codon start: 1
product: DUP240 family protein
translation: MNKYLFDHKIWSTPYYFYCEEDCHRLFLSFIEGRTFEKPTSNAEENVQETEAGESFTLNPGEDFQNCFPRQRIL
SIO_010081: YAR029W
subclass of: SO_0000673
so part of: YAR029W
location: 186321..186545
location: region:186321-186545:1
so has part: feature:186321-186545:1:exon

NP_009416.1
type: Protein
SIO_000068: ncbiprotein

S000000077
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:186321-186545:1:exon

YAR031W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PRM9
locus tag: YAR031W
so part of: sequence
location: <186836..>187732
location: region:186836-187732:1
so has part: feature:186836-187732:1:exon
subclass of: SO_0000010

851282
type: Gene
SIO_000068: ncbigene

position:186836:1
position: 186836
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:187732:1
position: 187732
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:186836-187732:1:exon

YAR031W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PRM9
locus tag: YAR031W
product: pheromone-regulated DUP240 family protein PRM9
transcript id: NM_001178224.1
SIO_010081: YAR031W
subclass of: SO_0000673
so part of: YAR031W
location: <186836..>187732
location: region:186836-187732:1
so has part: feature:186836-187732:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:186836-187732:1:exon

YAR031W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PRM9
locus tag: YAR031W
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762]
experiment: EXISTENCE:direct assay:GO:0005886 plasma membrane [PMID:12101299]
experiment: EXISTENCE:physical interaction:GO:0005783 endoplasmic reticulum [PMID:12925749]
note: Pheromone-regulated protein; contains 3 predicted transmembrane segments and an FF sequence, a motif involved in COPII binding; member of DUP240 gene family; PRM9 has a paralog, PRM8, that arose from a segmental duplication
codon start: 1
product: pheromone-regulated DUP240 family protein PRM9
translation: MSPQYHFYFVSFRNLVLNEKCLRSKKQVMKSFNWYKTDRYFDPHNILQHHSRAIEKTRYKLGMQTSSESTDAKSDFLDEPSAYLIEKNVALPKDIFGSYLSYWIYEVTRHKAAVILLVLIVTSILLLVFFYNTEFCVAFEILLFSFCFPGTCMVVIAFSEPIGDREFKVKLLMEIITRKPAVKGKEWRTITYKMNQYLFDHGLWDTPYYFYRDEDCHRYFLSLIKGRTFKKQKESSASNVKDAQSNDETAGTPNEAAESSSFSAGPNFIKLLTKAAEIEQQFQKEYWRQEYPGVDEFF
SIO_010081: YAR031W
subclass of: SO_0000673
so part of: YAR031W
location: 186836..187732
location: region:186836-187732:1
so has part: feature:186836-187732:1:exon

NP_009418.1
type: Protein
SIO_000068: ncbiprotein

S000000078
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:186836-187732:1:exon

YAR033W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: MST28
locus tag: YAR033W
so part of: sequence
location: <188107..>188811
location: region:188107-188811:1
so has part: feature:188107-188811:1:exon
subclass of: SO_0000010

851284
type: Gene
SIO_000068: ncbigene

position:188107:1
position: 188107
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:188811:1
position: 188811
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:188107-188811:1:exon

YAR033W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: MST28
locus tag: YAR033W
product: DUP240 family protein MST28
transcript id: NM_001178225.1
SIO_010081: YAR033W
subclass of: SO_0000673
so part of: YAR033W
location: <188107..>188811
location: region:188107-188811:1
so has part: feature:188107-188811:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:188107-188811:1:exon

YAR033W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: MST28
locus tag: YAR033W
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:26928762|PMID:12925749]
experiment: EXISTENCE:direct assay:GO:0005794 Golgi apparatus [PMID:12925749]
experiment: EXISTENCE:direct assay:GO:0016020 membrane [PMID:12925749]
experiment: EXISTENCE:genetic interaction:GO:0016050 vesicle organization [PMID:12925749]
experiment: EXISTENCE:mutant phenotype:GO:0005783 endoplasmic reticulum [PMID:12101299]
experiment: EXISTENCE:mutant phenotype:GO:0005886 plasma membrane [PMID:12101299]
experiment: EXISTENCE:physical interaction:GO:0016050 vesicle organization [PMID:12925749]
note: Putative integral membrane protein, involved in vesicle formation; forms complex with Mst27p; member of DUP240 gene family; binds COPI and COPII vesicles; MST28 has a paralog, MST27, that arose from a segmental duplication
codon start: 1
product: DUP240 family protein MST28
translation: MQTPPESTDVKLDTLNEPSAHLIEKNVALPKDIFRSYLSYWIYEIARYTPVMILSLVIGVLVLLIIFFNDNEACVFNSAIFAFTSLVGLLIILSDGNPKLVSRRNFRTELLVDVITRKPAVEGKEWRIITYNMNQYLFNHGQWHTPYYFYSDEDCYRYFLRLVEGVTPKKQTATSIGNSPVTAKPEDAIESASPSSRLNYQNFLLKAAEIERQAQENYWRRRHPNIDALLKKTE
SIO_010081: YAR033W
subclass of: SO_0000673
so part of: YAR033W
location: 188107..188811
location: region:188107-188811:1
so has part: feature:188107-188811:1:exon

NP_009419.1
type: Protein
SIO_000068: ncbiprotein

S000000079
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:188107-188811:1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty2 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: 189426..189757
location: region:189426-189757:1
so has part: feature:189426-189757:1:region

S000006794
type: SGD
SIO_000068: sgd

position:189426:1
position: 189426
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:189757:1
position: 189757
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:189426-189757:1:region

YAR035W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: YAT1
locus tag: YAR035W
so part of: sequence
location: <190193..>192256
location: region:190193-192256:1
so has part: feature:190193-192256:1:exon
subclass of: SO_0000010

851285
type: Gene
SIO_000068: ncbigene

position:190193:1
position: 190193
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:192256:1
position: 192256
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:190193-192256:1:exon

YAR035W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: YAT1
locus tag: YAR035W
product: carnitine O-acetyltransferase YAT1
transcript id: NM_001178226.1
SIO_010081: YAR035W
subclass of: SO_0000673
so part of: YAR035W
location: <190193..>192256
location: region:190193-192256:1
so has part: feature:190193-192256:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:190193-192256:1:exon

YAR035W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: YAT1
locus tag: YAR035W
EC number: 2.3.1.7
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:18427809|PMID:11914276|PMID:14576278|PMID:16823961]
experiment: EXISTENCE:mutant phenotype:GO:0009437 carnitine metabolic process [PMID:11329169]
note: Outer mitochondrial carnitine acetyltransferase; minor ethanol-inducible enzyme involved in transport of activated acyl groups from the cytoplasm into the mitochondrial matrix; phosphorylated
codon start: 1
product: carnitine O-acetyltransferase YAT1
translation: MPNLKRLPIPPLQDTLNRYLARVEPLQDERQNRRTRRTVLSAENLDALNTLHERLLEYDARLAESNPESSYIEQFWYDAYLLYDATVVLNVNPYFQLQDDPTIKDTPETAAQGPYGAHTVQVRRAARLTTSILKFIRQIRHGTLRTDTVRGKTPLSMDQYERLFGSSRIPPGPGEPSCHLQTDATSHHVVAMYRGQFYWFDVLDTRNEPIFATPEQLEWNLYSIIMDAESAGSGSAPFGVFTTESRRVWSNIRDYLFHADDCTNWRNLKLIDSALFVVCLDDVAFAADQQDELTRSMLCGTSTINLDPHQHQPPLNVQTGTCLNRWYDKLQLIVTKNGKAGINFEHTGVDGHTVLRLATDIYTDSILSFARGVTKNVVDIFSDDDGKPSSSSLASAAHSANLITIPRKLEWRTDNFLQSSLHFAETRISDLISQYEFVNLDFSNYGASHIKTVFKCSPDAFVQQVFQVAYFALYGRFETVYEPAMTKAFQNGRTEAIRSVTGQSKLFVKSLLDQDASDATKIQLLHDACTAHSQITRECSQGLGQDRHLYALYCLWNQWYKDKLELPPIFRDKSWTTMQNNVLSTSNCGNPCLKSFGFGPVTANGFGIGYIIRDHSVSVVVSSRHRQTARFASLMEKSLLEIDRIFKRQQARAAKPAARTTASANTKSEDMKYLLSGYDYFDVSVSG
SIO_010081: YAR035W
subclass of: SO_0000673
so part of: YAR035W
location: 190193..192256
location: region:190193-192256:1
so has part: feature:190193-192256:1:exon

NP_009420.1
type: Protein
SIO_000068: ncbiprotein

S000000080
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:190193-192256:1:exon

YAR035C-A
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YAR035C-A
so part of: sequence
location: complement(<192337..>192417)
location: region:192337-192417:-1
so has part: feature:192337-192417:-1:exon
subclass of: SO_0000010

1466430
type: Gene
SIO_000068: ncbigene

position:192337:-1
position: 192337
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

position:192417:-1
position: 192417
reference: sequence
type: ReverseStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:192337-192417:-1:exon

YAR035C-A
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YAR035C-A
product: uncharacterized protein
transcript id: NM_001184583.1
SIO_010081: YAR035C-A
subclass of: SO_0000673
so part of: YAR035C-A
location: complement(<192337..>192417)
location: region:192337-192417:-1
so has part: feature:192337-192417:-1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:192337-192417:-1:exon

YAR035C-A
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YAR035C-A
experiment: EXISTENCE:direct assay:GO:0005739 mitochondrion [PMID:32034123]
note: hypothetical protein; emerging ORF that arose de novo from non-genic locus; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching; localizes to mitochondria
codon start: 1
product: uncharacterized protein
translation: MRLNYSRCYYSSQRRRQSLPKRFPLI
SIO_010081: YAR035C-A
subclass of: SO_0000673
so part of: YAR035C-A
location: complement(192337..192417)
location: region:192337-192417:-1
so has part: feature:192337-192417:-1:exon

NP_878042.1
type: Protein
SIO_000068: ncbiprotein

S000028595
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:192337-192417:-1:exon

YAR042W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: OSH1
alternative label: YAR044W
gene: SWH1
locus tag: YAR042W
gene synonym: OSH1; YAR044W
so part of: sequence
location: <192619..>196185
location: region:192619-196185:1
so has part: feature:192619-196185:1:exon
subclass of: SO_0000010

851286
type: Gene
SIO_000068: ncbigene

position:192619:1
position: 192619
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:196185:1
position: 196185
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:192619-196185:1:exon

YAR042W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: OSH1
alternative label: YAR044W
gene: SWH1
locus tag: YAR042W
gene synonym: OSH1; YAR044W
product: oxysterol-binding protein related protein SWH1
transcript id: NM_001178227.1
SIO_010081: YAR042W
subclass of: SO_0000673
so part of: YAR042W
location: <192619..>196185
location: region:192619-196185:1
so has part: feature:192619-196185:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:192619-196185:1:exon

YAR042W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: OSH1
alternative label: YAR044W
gene: SWH1
locus tag: YAR042W
gene synonym: OSH1; YAR044W
experiment: EXISTENCE:direct assay:GO:0000138 Golgi trans cisterna [PMID:11408574]
experiment: EXISTENCE:direct assay:GO:0005635 nuclear envelope [PMID:12727870]
experiment: EXISTENCE:direct assay:GO:0005769 early endosome [PMID:11408574]
experiment: EXISTENCE:direct assay:GO:0005783 endoplasmic reticulum [PMID:12727870]
experiment: EXISTENCE:direct assay:GO:0008289 lipid binding [PMID:20008566]
experiment: EXISTENCE:direct assay:GO:0015918 sterol transport [PMID:20008566]
experiment: EXISTENCE:direct assay:GO:0071561 nucleus-vacuole junction [PMID:25420878]
experiment: EXISTENCE:direct assay:GO:0120015 sterol transfer activity [PMID:20008566]
experiment: EXISTENCE:genetic interaction:GO:0006887 exocytosis [PMID:17004323]
experiment: EXISTENCE:genetic interaction:GO:0006897 endocytosis [PMID:15173322]
experiment: EXISTENCE:genetic interaction:GO:0015918 sterol transport [PMID:16585271]
experiment: EXISTENCE:genetic interaction:GO:0030011 maintenance of cell polarity [PMID:17004323]
experiment: EXISTENCE:genetic interaction:GO:0034727 piecemeal microautophagy of the nucleus [PMID:15367582]
note: Protein similar to mammalian oxysterol-binding protein; contains ankyrin repeats and FFAT motif; interacts with ER anchor Scs2p at the nucleus-vacuole junction; regulated by sterol binding; SWH1 has a paralog, OSH2, that arose from the whole genome duplication
codon start: 1
product: oxysterol-binding protein related protein SWH1
translation: MEQPDLSSVAISKPLLKLKLLDALRQGSFPNLQDLLKKQFQPLDDPNVQQVLHLMLHYAVQVAPMAVIKEIVHHWVSTTNTTFLNIHLDLNERDSNGNTPLHIAAYQSRGDIVAFLLDQPTINDCVLNNSHLQAIEMCKNLNIAQMMQVKRSTYVAETAQEFRTAFNNRDFGHLESILSSPRNAELLDINGMDPETGDTVLHEFVKKRDVIMCRWLLEHGADPFKRDRKGKLPIELVRKVNENDTATNTKIAIDIELKKLLERATREQSVIDVTNNNLHEAPTYKGYLKKWTNFAQGYKLRWFILSSDGKLSYYIDQADTKNACRGSLNMSSCSLHLDSSEKLKFEIIGGNNGVIRWHLKGNHPIETNRWVWAIQGAIRYAKDREILLHNGPYSPSLALSHGLSSKVSNKENLHATSKRLTKSPHLSKSTLTQNDHDNDDDSTNNNNNKSNNDYDDNNNNNNNDDDDYDDDDESRPLIEPLPLISSRSQSLSEITPGPHSRKSTVSSTRAADIPSDDEGYSEDDSDDDGNSSYTMENGGENDGDEDLNAIYGPYIQKLHMLQRSISIELASLNELLQDKQQHDEYWNTVNTSIETVSEFFDKLNRLTSQREKRMIAQMTKQRDVNNVWIQSVKDLEMELVDKDEKLVALDKERKNLKKMLQKKLNNQPQVETEANEESDDANSMIKGSQESTNTLEEIVKFIEATKESDEDSDADEFFDAEEAASDKKANDSEDLTTNKETPANAKPQEEAPEDESLIVISSPQVEKKNQLLKEGSFVGYEDPVRTKLALDEDNRPKIGLWSVLKSMVGQDLTKLTLPVSFNEPTSLLQRVSEDIEYSHILDQAATFEDSSLRMLYVAAFTASMYASTTNRVSKPFNPLLGETFEYARTDGQYRFFTEQVSHHPPISATWTESPKWDFYGECNVDSSFNGRTFAVQHLGLWYITIRPDHNISVPEETYSWKKPNNTVIGILMGKPQVDNSGDVKVTNHTTGDYCMLHYKAHGWTSAGAYEVRGEVFNKDDKKLWVLGGHWNDSIYGKKVTARGGELTLDRIKTANSATGGPKLDGSKFLIWKANERPSVPFNLTSFALTLNALPPHLIPYLAPTDSRLRPDQRAMENGEYDKAAAEKHRVEVKQRAAKKEREQKGEEYRPKWFVQEEHPVTKSLYWKFNGEYWNKRKNHDFKDCADIF
SIO_010081: YAR042W
subclass of: SO_0000673
so part of: YAR042W
location: 192619..196185
location: region:192619-196185:1
so has part: feature:192619-196185:1:exon

NP_009421.3
type: Protein
SIO_000068: ncbiprotein

S000000081
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:192619-196185:1:exon

YAR050W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: FLO2
alternative label: FLO4
gene: FLO1
locus tag: YAR050W
gene synonym: FLO2; FLO4
so part of: sequence
location: <203403..>208016
location: region:203403-208016:1
so has part: feature:203403-208016:1:exon
subclass of: SO_0000010

851289
type: Gene
SIO_000068: ncbigene

position:203403:1
position: 203403
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:208016:1
position: 208016
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:203403-208016:1:exon

YAR050W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: FLO2
alternative label: FLO4
gene: FLO1
locus tag: YAR050W
gene synonym: FLO2; FLO4
product: flocculin FLO1
transcript id: NM_001178230.1
SIO_010081: YAR050W
subclass of: SO_0000673
so part of: YAR050W
location: <203403..>208016
location: region:203403-208016:1
so has part: feature:203403-208016:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:203403-208016:1:exon

YAR050W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
alternative label: FLO2
alternative label: FLO4
gene: FLO1
locus tag: YAR050W
gene synonym: FLO2; FLO4
experiment: EXISTENCE:direct assay:GO:0009277 fungal-type cell wall [PMID:9483793|PMID:11956747]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
experiment: EXISTENCE:mutant phenotype:GO:0000128 flocculation [PMID:19013280|PMID:19420680|PMID:23383507|PMID:7483845|PM ID:11027318]
experiment: EXISTENCE:mutant phenotype:GO:0005537 mannose binding [PMID:9851992]
note: Lectin-like protein involved in flocculation; cell wall protein that binds mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin sensitive and heat resistant; important for co-flocculation with other yeasts, mediating interaction with specific species; FLO1 has a paralog, FLO5, that arose from a segmental duplication
codon start: 1
product: flocculin FLO1
translation: MTMPHRYMFLAVFTLLALTSVASGATEACLPAGQRKSGMNINFYQYSLKDSSTYSNAAYMAYGYASKTKLGSVGGQTDISIDYNIPCVSSSGTFPCPQEDSYGNWGCKGMGACSNSQGIAYWSTDLFGFYTTPTNVTLEMTGYFLPPQTGSYTFKFATVDDSAILSVGGATAFNCCAQQQPPITSTNFTIDGIKPWGGSLPPNIEGTVYMYAGYYYPMKVVYSNAVSWGTLPISVTLPDGTTVSDDFEGYVYSFDDDLSQSNCTVPDPSNYAVSTTTTTTEPWTGTFTSTSTEMTTVTGTNGVPTDETVIVIRTPTTASTIITTTEPWNSTFTSTSTELTTVTGTNGVRTDETIIVIRTPTTATTAITTTEPWNSTFTSTSTELTTVTGTNGLPTDETIIVIRTPTTATTAMTTTQPWNDTFTSTSTELTTVTGTNGLPTDETIIVIRTPTTATTAMTTTQPWNDTFTSTSTELTTVTGTNGLPTDETIIVIRTPTTATTAMTTTQPWNDTFTSTSTEITTVTGTNGLPTDETIIVIRTPTTATTAMTTPQPWNDTFTSTSTEMTTVTGTNGLPTDETIIVIRTPTTATTAITTTEPWNSTFTSTSTEMTTVTGTNGLPTDETIIVIRTPTTATTAITTTQPWNDTFTSTSTEMTTVTGTNGLPTDETIIVIRTPTTATTAMTTTQPWNDTFTSTSTEITTVTGTTGLPTDETIIVIRTPTTATTAMTTTQPWNDTFTSTSTEMTTVTGTNGVPTDETVIVIRTPTSEGLISTTTEPWTGTFTSTSTEMTTVTGTNGQPTDETVIVIRTPTSEGLVTTTTEPWTGTFTSTSTEMTTITGTNGVPTDETVIVIRTPTSEGLISTTTEPWTGTFTSTSTEMTTITGTNGQPTDETVIVIRTPTSEGLISTTTEPWTGTFTSTSTEMTHVTGTNGVPTDETVIVIRTPTSEGLISTTTEPWTGTFTSTSTEVTTITGTNGQPTDETVIVIRTPTSEGLISTTTEPWTGTFTSTSTEMTTVTGTNGQPTDETVIVIRTPTSEGLVTTTTEPWTGTFTSTSTEMSTVTGTNGLPTDETVIVVKTPTTAISSSLSSSSSGQITSSITSSRPIITPFYPSNGTSVISSSVISSSVTSSLFTSSPVISSSVISSSTTTSTSIFSESSKSSVIPTSSSTSGSSESETSSAGSVSSSSFISSESSKSPTYSSSSLPLVTSATTSQETASSLPPATTTKTSEQTTLVTVTSCESHVCTESISPAIVSTATVTVSGVTTEYTTWCPISTTETTKQTKGTTEQTTETTKQTTVVTISSCESDVCSKTASPAIVSTSTATINGVTTEYTTWCPISTTESRQQTTLVTVTSCESGVCSETASPAIVSTATATVNDVVTVYPTWRPQTANEESVSSKMNSATGETTTNTLAAETTTNTVAAETITNTGAAETKTVVTSSLSRSNHAETQTASATDVIGHSSSVVSVSETGNTKSLTSSGLSTMSQQPRSTPASSMVGYSTASLEISTYAGSANSLLAGSGLSVFIASLLLAII
SIO_010081: YAR050W
subclass of: SO_0000673
so part of: YAR050W
location: 203403..208016
location: region:203403-208016:1
so has part: feature:203403-208016:1:exon

NP_009424.1
type: Protein
SIO_000068: ncbiprotein

S000000084
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:203403-208016:1:exon

repeat_region
type: Repeat Region
subclass of: SO_0000657
RO_0002162: 559292
note: Ty1 LTR
rpt type: long_terminal_repeat
so part of: sequence
location: complement(209448..209778)
location: region:209448-209778:-1
so has part: feature:209448-209778:-1:region

S000006791
type: SGD
SIO_000068: sgd

position:209448:-1
position: 209448
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

position:209778:-1
position: 209778
reference: sequence
type: ReverseStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:209448-209778:-1:region

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS111; Autonomously Replicating Sequence
so part of: sequence
location: 214888..215644
location: region:214888-215644:1
so has part: feature:214888-215644:1:region

S000121256
type: SGD
SIO_000068: sgd

position:214888:1
position: 214888
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:215644:1
position: 215644
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:214888-215644:1:region

YAR061W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
alternative label: YAR062W
locus tag: YAR061W
gene synonym: YAR062W
note: Pseudogenic fragment with similarity to flocculins; YAR061W has a paralog, YHR212W-A, that arose from a segmental duplication
pseudo: true
so part of: sequence
location: 218140..219145
location: region:218140-219145:1
so has part: feature:218140-219145:1:exon

851292
type: Gene
SIO_000068: ncbigene

S000000087
type: SGD
SIO_000068: sgd

position:218140:1
position: 218140
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:219145:1
position: 219145
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:218140-219145:1:exon

YAR061W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
alternative label: YAR062W
locus tag: YAR061W
gene synonym: YAR062W
pseudo: true
SIO_010081: YAR061W
subclass of: SO_0000673
so part of: YAR061W
location: 218140..219145
location: region:218140-219145:1
so has part: feature:218140-219145:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:218140-219145:1:exon

YAR064W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YAR064W
so part of: sequence
location: <220198..>220497
location: region:220198-220497:1
so has part: feature:220198-220497:1:exon
subclass of: SO_0000010

851294
type: Gene
SIO_000068: ncbigene

position:220198:1
position: 220198
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:220497:1
position: 220497
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:220198-220497:1:exon

YAR064W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YAR064W
product: uncharacterized protein
transcript id: NM_001178235.1
SIO_010081: YAR064W
subclass of: SO_0000673
so part of: YAR064W
location: <220198..>220497
location: region:220198-220497:1
so has part: feature:220198-220497:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:220198-220497:1:exon

YAR064W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YAR064W
note: Pseudogenic fragment with similarity to flocculins; YAR064W has a paralog, YHR213W-B, that arose from a segmental duplication
codon start: 1
product: uncharacterized protein
translation: MLIDFCCSYIAGTHGRERAPSFTGTFVSHVSGENNCRPRRSEITQPCASGTEKKHFAATEKPCTNSLEGSRKDFLSLPLGHSYLFLFCFWRMICSEPKL
SIO_010081: YAR064W
subclass of: SO_0000673
so part of: YAR064W
location: 220198..220497
location: region:220198-220497:1
so has part: feature:220198-220497:1:exon

NP_009429.1
type: Protein
SIO_000068: ncbiprotein

S000000089
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:220198-220497:1:exon

YAR066W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YAR066W
so part of: sequence
location: <221049..>221660
location: region:221049-221660:1
so has part: feature:221049-221660:1:exon
subclass of: SO_0000010

851295
type: Gene
SIO_000068: ncbigene

position:221049:1
position: 221049
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:221660:1
position: 221660
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:221049-221660:1:exon

YAR066W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YAR066W
product: uncharacterized protein
transcript id: NM_001180045.1
SIO_010081: YAR066W
subclass of: SO_0000673
so part of: YAR066W
location: <221049..>221660
location: region:221049-221660:1
so has part: feature:221049-221660:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:221049-221660:1:exon

YAR066W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YAR066W
note: Putative GPI protein; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum and vacuole respectively; YAR066W has a paralog, YHR214W, that arose from a segmental duplication
codon start: 1
product: uncharacterized protein
translation: MFNRFNKFQAAVALALLSRGALGDSYTNSTSSADLSSITSVSSASASATASDSLSSSDGTVYLPSTTISGDLTVTGKVIATEAVEVAAGGKLTLLDGEKYVFSSDLKVHGDLVVEKSEASYEGTAFDVSGETFEVSGNFSAEETGAVSASIYSFTPSSFKSSGDISLSLSKAKKGEVTFSPYSNAGTFSLSNAILNGGSVSGL
SIO_010081: YAR066W
subclass of: SO_0000673
so part of: YAR066W
location: 221049..221660
location: region:221049-221660:1
so has part: feature:221049-221660:1:exon

NP_009430.1
type: Protein
SIO_000068: ncbiprotein

S000002144
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:221049-221660:1:exon

YAR068W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
locus tag: YAR068W
so part of: sequence
location: <222406..>222891
location: region:222406-222891:1
so has part: feature:222406-222891:1:exon
subclass of: SO_0000010

851296
type: Gene
SIO_000068: ncbigene

position:222406:1
position: 222406
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:222891:1
position: 222891
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:222406-222891:1:exon

YAR068W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
locus tag: YAR068W
product: uncharacterized protein
transcript id: NM_001178236.1
SIO_010081: YAR068W
subclass of: SO_0000673
so part of: YAR068W
location: <222406..>222891
location: region:222406-222891:1
so has part: feature:222406-222891:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:222406-222891:1:exon

YAR068W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
locus tag: YAR068W
note: Fungal-specific hypothetical protein; induced in respiratory-deficient cells; YAR068W has a paralog, YHR214W-A, that arose from a segmental duplication
codon start: 1
product: uncharacterized protein
translation: MPQVQSWFPVQKQPTLAVTFTPLPQLSHAHLPLPPSHLVTKTDAMFQHQLLPTQLQPFPPSHTPLLLLLTVTTMAVTPRLSLLNVLKKLQQPPFLQNHTLLLPLLTVTTTAVTPRLSLPRLPNKHHWPLAQSPSLLLQLLILLLPAPSLVLSFNPKVWLLV
SIO_010081: YAR068W
subclass of: SO_0000673
so part of: YAR068W
location: 222406..222891
location: region:222406-222891:1
so has part: feature:222406-222891:1:exon

NP_009431.1
type: Protein
SIO_000068: ncbiprotein

S000000091
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:222406-222891:1:exon

rep_origin
type: Replication Origin
subclass of: SO_0000296
RO_0002162: 559292
note: ARS112; Autonomously Replicating Sequence
so part of: sequence
location: 222880..224046
location: region:222880-224046:1
so has part: feature:222880-224046:1:region

S000121257
type: SGD
SIO_000068: sgd

position:222880:1
position: 222880
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:224046:1
position: 224046
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:222880-224046:1:region

YAR071W
type: Gene
subclass of: SO_0000704
RO_0002162: 559292
gene: PHO11
locus tag: YAR071W
so part of: sequence
location: <225460..>226863
location: region:225460-226863:1
so has part: feature:225460-226863:1:exon
subclass of: SO_0000010

851299
type: Gene
SIO_000068: ncbigene

position:225460:1
position: 225460
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

position:226863:1
position: 226863
reference: sequence
type: ForwardStrandPosition
type: FuzzyPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:225460-226863:1:exon

YAR071W
type: Messenger RNA
subclass of: SO_0000234
RO_0002162: 559292
gene: PHO11
locus tag: YAR071W
product: acid phosphatase PHO11
transcript id: NM_001178239.1
SIO_010081: YAR071W
subclass of: SO_0000673
so part of: YAR071W
location: <225460..>226863
location: region:225460-226863:1
so has part: feature:225460-226863:1:exon

urn:…
SIO_000300: 1
SIO_000628: feature:225460-226863:1:exon

YAR071W
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 559292
gene: PHO11
locus tag: YAR071W
EC number: 3.1.3.2
experiment: EXISTENCE:direct assay:GO:0003993 acid phosphatase activity [PMID:8817921]
experiment: EXISTENCE:direct assay:GO:0005576 extracellular region [PMID:8817921]
experiment: EXISTENCE:direct assay:GO:0071944 cell periphery [PMID:26928762]
note: One of three repressible acid phosphatases; glycoprotein that is transported to the cell surface by the secretory pathway; induced by phosphate starvation and coordinately regulated by PHO4 and PHO2; PHO11 has a paralog, PHO12, that arose from a segmental duplication
codon start: 1
product: acid phosphatase PHO11
translation: MLKSAVYSILAASLVNAGTIPLGKLSDIDKIGTQTEIFPFLGGSGPYYSFPGDYGISRDLPESCEMKQVQMVGRHGERYPTVSKAKSIMTTWYKLSNYTGQFSGALSFLNDDYEFFIRDTKNLEMETTLANSVNVLNPYTGEMNAKRHARDFLAQYGYMVENQTSFAVFTSNSNRCHDTAQYFIDGLGDKFNISLQTISEAESAGANTLSAHHSCPAWDDDVNDDILKKYDTKYLSGIAKRLNKENKGLNLTSSDANTFFAWCAYEINARGYSDICNIFTKDELVRFSYGQDLETYYQTGPGYDVVRSVGANLFNASVKLLKESEVQDQKVWLSFTHDTDILNYLTTIGIIDDKNNLTAEHVPFMENTFHRSWYVPQGARVYTEKFQCSNDTYVRYVINDAVVPIETCSTGPGFSCEINDFYDYAEKRVAGTDFLKVCNVSSVSNSTELTFFWDWNTKHYNDTLLKQ
SIO_010081: YAR071W
subclass of: SO_0000673
so part of: YAR071W
location: 225460..226863
location: region:225460-226863:1
so has part: feature:225460-226863:1:exon

NP_009434.1
type: Protein
SIO_000068: ncbiprotein

S000000094
type: SGD
SIO_000068: sgd

urn:…
SIO_000300: 1
SIO_000628: feature:225460-226863:1:exon

telomere
type: Telomere
subclass of: SO_0000624
RO_0002162: 559292
note: TEL01R; Telomeric region on the right arm of Chromosome I; composed of an X element core sequence and a short terminal stretch of telomeric repeats
so part of: sequence
location: 229411..230218
location: region:229411-230218:1
so has part: feature:229411-230218:1:region

S000028937
type: SGD
SIO_000068: sgd

position:229411:1
position: 229411
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:229411-230218:1:region