Phaeodactylum tricornutum CCAP 1055/1 chromosome 13, whole genome shotgun sequence.
Eukaryota; Stramenopiles; Bacillariophyta; Bacillariophyceae; Bacillariophycidae; Naviculales; Phaeodactylaceae; Phaeodactylum.
The Phaeodactylum genome reveals the evolutionary history of diatom genomes
Submitted (15-JUN-2017) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (12-AUG-2008) US DOE Joint Genome Institute, 2800 Mitchell Drive B100, Walnut Creek, CA 94598-1698, USA
PROVISIONAL REFSEQ: This record has not yet been subject to final\nNCBI review. The reference sequence is identical to CM000615.\nURL -- http://www.jgi.doe.gov/phaeodactylum\nJGI Project ID: 3634397\nContacts: Chris Bowler (cbowler@biologie.ens.fr)\n Igor Grigoriev (ivgrigoriev@lbl.gov)\nThe clone of P. tricornutum that was sequenced is CCAP1055/1 and is\navailable from the Culture collection of Algae and Protozoa\n(http://www.ccap.ac.uk). This clone represents a monoclonal culture\nderived from a fusiform cell in May 2003 from strain CCCP632, which\nwas originally isolated in 1956 off Blackpool (U.K.). It has been\nmaintained in culture continuously in F/2 medium.\nAnnotation was done by the JGI Annotation team and the Diatom\nConsortium.\nChromosomes 3 and 11 are complete and present in GenBank records\nCP001142 and CP001141, respectively.\nThe JGI and collaborators endorse the principles for the\ndistribution and use of large scale sequencing data adopted by the\nlarger genome sequencing community and urge users of this data to\nfollow them. It is our intention to publish the work of this\nproject in a timely fashion and we welcome collaborative\ninteraction on the project and analysis.\n(http://www.genome.gov/page.cfm?pageID=10506376)\nAnnotated scaffolds were added in December 2008.\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: INSDC submitter\nAnnotation Status :: Full annotation\nAnnotation Pipeline :: Eukaryotic Annotation Propagation Pipeline\n##Genome-Annotation-Data-END##
Gene of unknown function. Has 1 transmembrane domain and is highly expressed under conditions of nitrate depletion.; Pt_34041, Gene of unknownn function
Catalyzes the first step of phospholipid synthesis. Converts acyl-CoA and glycerol-3-phosphate to 1-acyl-glycerol-3-phosphate (lysophosphatidic acid). Probably ER-membrane bound.; G-3-P acyltransferase; Dihydroxyacetone phosphate acyltransferase
regulatory proteasome non-atpase subunit 6
26S proteasome regulatory non ATPase subunit, homolog to plant S9 subunit
Sigma (small) subunit of the AP4 complex, ortholog of T. pseudonana TPS_142588
enzyme involved in N-Glycan Biosynthesis
A chloroplast-localized glycosyl transferase, possibly a galactosyl transferase involved in glycolipid synthesis. Reaction catalyzed: UDP-galactose + 1,2-diacyl-sn-glycerol = UDP + 3-beta-D-galactosyl-1,2-diacyl-sn-glycerol.; glycosyl transferase family 28
putative bipartite targeting presequence, signal- and transit-peptides predicted at N-terminus
Spc97 are core-proteins of Microtubule organizing center (MTOC)
probable zinc-dependent alcohol dehydrogenase : aldehyde & ketone synthesis
Rab-family small GTPase, ortholog of T.pseudonana TPS_98354
Sequence similarity to the anti-viral guanylate-binding protein (GBP). GBP transcription is induced by interferon-gamma during macrophage induction. This family contains GBP1 and GPB2, both GTPases capable of binding GTP, GDP and GMP.
Hypothetical protein. Appears to be a member of the Multi Antimicrobial Extrusion (MATE) family which functions as drug/sodium antiporters. These proteins mediate resistance to a wide range of cationic dyes, fluroquinolones, aminoglycosides and other structurally diverse antibodies and drugs. MATE proteins are found in bacteria, archaea and eukaryotes.
signal peptidase complex subunit 1 homolog, probably ER located
Beta adaptin, large invariable subunit of AP4 complex
Ascorbate peroxidase (AP) is the main enzyme responsible for hydrogen peroxide removal in the chloroplasts and cytosol of higher plants; ascorbate is a strong anti-oxidant
Probably involved in damage recognation initiation step of DNA Nucleotide Excision Repair (NER), in association with a RAD23 protein homolog
Glutaredoxin, probably mitochondrial, possesses N-terminal extension
Pyridoxal-dependent decarboxylases acting on ornithine, lysine, arginine and related substrates can be classified into two different families on the basis of sequence similarities.; DAP decarboxylase
Precise function unknown. Contains N-terminal targeting peptide and ankyrin domain proximal to C-terminus.; Ankyrin-repeat-containing gene of unknownn function
This family consists of part of the bifunctional enzyme riboflavin kinase / FAD synthetase. These enzymes have both ATP:riboflavin 5'-phospho transferase and ATP:FMN-adenylyltransferase activities. They catalyse the 5'-phosphorylation of riboflavin to FMN and the adenylylation of FMN to FAD.
Triosephosphate isomerase probably catalyzes D-glyceraldhyde 3-phosphate to glycerone phosphate
Catalyzes the transfer of malonyl-CoA to malonyl-ACP. A subunit of the type II, plastid-targeted FAS. Probably contains a bipartite plastid targeting signal.
RNA splicing factor associated with the spliceosome. May function in the second step of pre-mRNA splicing. Highly closed to the Thalassiosira protein thaps1 137278.
transporter, major facilitator superfamily and tetracycline resistance protein
The Major Facilitator Superfamily (MFS) transporters are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. Also contains sequence similiarities to the transposon Tn10-encoded tetracycline resistance (Tcr) protein. This functions as a metal-tetracycline/H + antiporter
mitotic spindle assembly checkpoint protein
Mitotic checkpoint protein. This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur.
delta 9 desaturase, microsomal membrane-bound, probably acts primarily on acyl-CoA ester substrates, specifically for the conversion of stearoyl-CoA to Oleoyl-CoA. Distinct from plastid-localized, soluble, acyl-ACP delta 9 desaturase. Contains three typical 'Histidine-box' motifs. Oxygen-requiring, di-iron binding, oxidoreductase. Most similar to metazoan delta 9 desaturases.
fucoxanthin chlorophyll a/c protein, deviant
probable dihydrolipoamide acetyl transferase Pyruvate metabolism & Glycolysis
Possibly a formamidase catalyzes formamide+H2O =formate+NH3
Putative Dynamin GTPase, ortholog of T. pseudonana TPS_108630, most similar to dictyostelid and mammalian orthologs
putative CAAX prenyl protease, protein-specific prenyl protease
unknown function; similarity to Entamoeba protein; membrane protein; unknownn protein