Phaeodactylum tricornutum CCAP 1055/1 chromosome 11, complete sequence.
Eukaryota; Stramenopiles; Bacillariophyta; Bacillariophyceae; Bacillariophycidae; Naviculales; Phaeodactylaceae; Phaeodactylum.
The Phaeodactylum genome reveals the evolutionary history of diatom genomes
Submitted (15-JUN-2017) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (14-AUG-2008) US DOE Joint Genome Institute, 2800 Mitchell Drive B100, Walnut Creek, CA 94598-1698, USA
PROVISIONAL REFSEQ: This record has not yet been subject to final\nNCBI review. The reference sequence is identical to CP001141.\nThe remaining chromosomes for this strain have been deposited under\nthe Whole Genome Shotgun project accession ABQD00000000.\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: INSDC submitter\nAnnotation Status :: Full annotation\nAnnotation Pipeline :: Eukaryotic Annotation Propagation Pipeline\n##Genome-Annotation-Data-END##\nCOMPLETENESS: full length.
Probably catalyzing the reaction myoinositol+NAD=2,4,6/3, 5-pentahydroxycyclohexanone+NADH+H
Catalyzes the liberation of acetyl-CoA from 3-oxoacyl-CoA. Acyl-CoA + CoA = Acetyl-CoA + Acyl-CoA (2 fewer carbons).; 3-oxoacyl-CoA thiolase, putative mitochondrial precursor
Precise function unknown. Probably catalyzes the transfer of sugar moieties from activated donor molecules (typically UDP-, ADP-, GDP-, or CMP-linked sugars) to specific acceptor molecules, forming glycosidic bonds. Functions in the ER-Golgi network.
Cytochrome b6-f complex iron-sulfur subunit
RNA polymerase II (36 kDa polypeptide B subunit 3)
Has EST support; Alternative splicing variant 2
Fructose-1,6-bisphosphate aldolase precursor (FbaC1) gene, GenBank Accession AY191866, contains bipartite plastid targeting presequence, signal- and transit-peptides predicted at N-terminus with conserved motif at signal peptide cleavage site || Probably catalyzes the reaction: D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate in the pentose phosphate pathway.; Alternative splicing variant 2
glycine decarboxylase T-protein, aminomethyl transferase, GDCT, GCST, GCVT
Has EST support. (null); Alternative splicing variant 1
Glycine decarboxylase T-protein, also called glycine cleavage system T-protein (GCST, GCVT). Catalyzes the formation of serine from two glycine with consequent production of CO2 and NH3. Part of the glycolate cycle (C2 cycle) in photorespiration.; Alternative splicing variant 1
protoporphyrin IX magnesium chelatase, subunit H
H subunit of the magnesium chelatase complex responsible for magnesium insertion into the protoporphyrin IX ring in the biosynthesis of both chlorophyll and bacteriochlorophyll; located in chloroplast
putative Vacuolar Protein Sorting Vps45p, Sec1 domain-containing protein, syntaxin-binding protein
DNA topoisomerase I involved in DNA replication, recombination and repair. Highly closed to the Thalassiosira protein thaps1 165881.
protein containing a MCM domain found in DNA-dependent ATPases required for the initiation of eukariotic DNA replication. There is a family of six proteins interacting directly with autonomously replicating sequences (ARS). Highly closed to the protein of Thalassiosira thaps1 116330.
enzyme involved in N-Glycan Biosynthesis
Probable Acetate-CoA ligase ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA Also acts on propanoate and propenoate. Involved in Glycolysis / Gluconeogenesis, Pyruvate metabolism, Propanoate metabolism and Reductive carboxylate cycle (CO2 fixation)
Rap/Ran-GAP domain expressed protein of unknown function
Hypothetical protein with aminotransferase and TonB box domains. TonB box domains may occur in membrane receptor proteins that carry out high-affinity binding and energy-dependent uptake of specific substrates
One of three enzymes involved in 4-aminobutyrate (GABA) degradation, catalyzing the NAD+ dependent oxidation of succinic semialdehyde to succinate for metabolism by the TCA cycle. Reaction catalyzed: succinate semialdehyde + NAD+ + H2O = succinate + NADH + 2H+. Potential roles in glutamate metabolism and butanoate metabolism.
anthranilate synthase. anthranilate synthetase. chorismate lyase
expressed protein putatively targeted to plastid, Tryptophan biosynthesis
Proteasomes consist of 14 different subunits; one of them is zeta. zeta subunits possess RNase activity (ribonuclease activity); locus PSA5_HUMAN, accession P28066
Precise function unknown. Contains N-terminal targeting peptide and ankyrin domain proximal to C-terminus.; Ankyrin-repeat-containing gene of unknownn function
Catalyzes the interconversion of UDP-D-glucose and UDP-D-galactose.
Probably catalyzes the reaction: 6-phospho-D-gluconate = 2-dehydro-3-deoxy-6-phospho-D-gluconate + H2O
Similar to bacterial and plastidic nucleotide transporters (NTTs)
hypothetical protein containing glutathione peroxidase domain
Likely two genes represented by this model. There is EST evidence for both but no alignments or information for the first half of the model (putative hypothetical protein). The second half (3' end) has glutathione peroxidase domain. Glutathione peroxidases function to protect against damage from endogenously-formed hydroxyperoxides, catalyzing the reduction of hydroxyperoxides by glutathione
similar to the rpl2 gene in the chloroplas genome of C. reinhardtii
SMC proteins family form heterodimers and are involved in structural maintenace of chromosomes. Highly closed to the Thalassiosira protein thaps1 139532.
ATP-dependent polydeoribonucleotide synthase, highly closed to the Thalassiosira protein thaps1 13204.
voltage activated chloride channel CLC7 type
Conserved features of animal like voltage activated ion channel CLC7 group. Very similar to Pt_29538
unknown function; similarity to P-loop containing nucleoside triphosphate hydrolases; weak similarity to ATP-dependent RNA helicase; unknownn protein
delta 5 fatty acid desaturase, membrane bound, di-iron oxidoreductase, containing three 'histidine box' motifs and a cytochrome b5 fusion domain. Involved in the biosynthesis of eicosapentaenoic and docasahexaenoic acids. When expressed in yeast, mediates the desaturation of exogenous free fatty acids. Probably prefers endogenous acyl-lipids as substrates.
Probable oxidoreductases acting on the CH-OH group of donors with NAD+ or NADP+ as acceptor. Catalyses 2-deoxy-D-gluconate +NAD = 3-dehydro-2-deoxy-D-gluconate+NADH +H
required for spermine/spermidine biosynthesis
HSP20 are synthesized in response to heat shock or other environmental stress. They seem to act as chaperones that can protect other proteins against heat-induced denaturation and aggregation; HSP20) family
similarity to R3H domain of the X1 box binding protein (NF-X1); The function of the domain is predicted to be binding ssDNA or ssRNA in a sequence-specific manner
H-type cyclin. Interacts with D-type CDK to form a CDK activating kinase (CAK)
unknown function; similarity to bacterial Virulence factor with pectin lyase fold and Polymorphic membrane protein of Chlamydia; unknownn protein
putative syntaxin, t-SNARE component, similar to plant Syp41-like proteins
ribulose-1,5-bisphosphate carboxylase/oxygenase small subunit N-methyltransferase I
putative ribulose-1,5-bisphosphate carboxylase/oxygenase small subunit N-methyltransferase I; N terminus contains putative ER signal peptide (SignalP prediction score = 0.999); putatively chloroplast targeted
similar to the step II splicing factor essential during the second step in the pre-mRNA splicing process by restructuring the spliceosome. Highly closed to the Thalassiosira protein thaps1 122669.
silent information regulator protein Sir2
NAD-dependant histone deacetylase. Yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA
Glucose-6-phosphate dehydrogenase / 6-Phosphogluconate dehydrognase fusion protein, both enzymes are fused by a short linker, probably cytosolic
Putative Golgi v-SNARE component, similar to plant Membrin11 and animal GOSR proteins
molecular chaperone; located in chloroplast
reduction of ferric iron; contains N-terminal Ferric reductase-like transmembrane component and NADPH oxidase domain; secretory pathway
UDP-sulfoquinovose synthase, plastid precursor
Participates in the synthesis of plastid-localized glycolipids, catalyzes the reaction: UDP-glucose + sulfite = UDP-6-sulfoquinovose + H2O. Uses NAD+ as co-factor.
two component sensor, Histidine Kinase, Response Regulator