Phaeodactylum tricornutum CCAP 1055/1 chromosome 3, complete sequence.
Eukaryota; Stramenopiles; Bacillariophyta; Bacillariophyceae; Bacillariophycidae; Naviculales; Phaeodactylaceae; Phaeodactylum.
The Phaeodactylum genome reveals the evolutionary history of diatom genomes
Submitted (15-JUN-2017) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (14-AUG-2008) US DOE Joint Genome Institute, 2800 Mitchell Drive B100, Walnut Creek, CA 94598-1698, USA
PROVISIONAL REFSEQ: This record has not yet been subject to final\nNCBI review. The reference sequence is identical to CP001142.\nThe remaining chromosomes for this strain have been deposited under\nthe Whole Genome Shotgun project accession ABQD00000000.\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: INSDC submitter\nAnnotation Status :: Full annotation\nAnnotation Pipeline :: Eukaryotic Annotation Propagation Pipeline\n##Genome-Annotation-Data-END##\nCOMPLETENESS: full length.
molecular chaperone; located in mitochondrion
Catalyzes the formation of acyl-CoA from free fatty acid and CoA. Similar to metazoan long-chain acyl-CoA ligases. Lacks transmembrane domains by computer-prediction.; long chain acyl-CoA ligase
unknown function; contains conserved Cys-rich domain of unknown function; unknownn protein
bacterial type voltage activated sodium channel
Bacterial type voltage activated sodium channel. Presence of two paralogues on same chromosome and four orthologues in Thalassiosira.
vacuolar protein sorting-associated protein 35
Presumably involved in forming multi-protein complexes that facilitate retrograde transport of lytic vacuolar-targeting receptors back to the trans-Golgi network.
The CCT (CONSTANS, CO-like, and TOC1) domain is a highly conserved basic module of 43 amino acids, which is found near the C-terminus of plant proteins often involved in light signal transduction. The CCT domain is found in association with other domains, such as the B-box zinc finger, the GATA-type zinc finger, the ZIM motif or the response regulatory domain. The CCT domain contains a putative nuclear localisation signal within the second half of the CCT motif and has been shown to be involved in nuclear localization and probably also has a role in protein-protein interaction
translation elongation factor, EF-1, alpha subunit
Eukaryotic elongation factor 1 (EF-1) is responsible for the GTP-dependent binding of aminoacyl-tRNAs to ribosomes. This is the alpha sub unit and it is highly represented by ESTs for a nitrogen limited culture grown on NH4 as the sole N source.
fucoxanthin chlorophyll a/c protein, lhcr type
putative component of Rab geranyl-geranylation comlex, distantly similar to Rab esort protein and geranyl geranyl transferases, contains rab interaction domain
similarity to non-ligand gated Cation channels; family contains Sodium, Potassium, Calcium ion channels.
The timeless gene in Drosophila melanogaster and its homologues in a number of other insects and mammals (including human) are involved in circadian rhythm control. This family includes related proteins from a number of fungal species and from Arabidopsis thaliana.
phytoene desaturase. zeta-carotene desaturase. bacterial-like protein
Bacterial-like Phytoene desaturase/Zeta-carotene desaturase (CrtI, CrtN), expressed gene, possibly involved in carotenoid biosynthesis
Caltractin (Centrin), Protein of the Calmoduline like superfamily (EF hand domain protein)
succinate dehydrogenase cytochrome b subunit
Probably a component of the mitochondrial enzyme complex that oxidizes succinate to fumarate in the citric acid cycle. Reaction catalyzed: succinate + ubiquinone = fumarate + ubiquinol. This subunit has transmembrane domains, anchoring the SDH1 subunit to the membrane, and uses cytochrome b560 as co-factor.
unknown function; similarity to Proline-, glutamic acid-, leucine-rich proteins [PELP]; secretory pathway
gamma coatomer, subunit of the Coat Protein complex COP I
Calcium Binding Protein, EF Hand Superfamily(2 EF hands/one putative S100 subdomain)
Enzyme involved in N-glycan biosynthesis; beta subunit
SMC proteins family form heterodimers and act as an essential regulator of chromosome condensation. Highly closed to th Thalassiosira protein thaps1 128975.
unknown function; weak similarity to DNA-binding protein; unknownn protein
protein containing a MCM domain and belonging to a family of six proteins. They interact directly with autonomously replicating sequences (ARS). Highly closed to the Thalassiosira protein thaps1 111791
regulatory proteasome non-atpase subunit 10
26S proteasome regulatory non ATPase subunit, homolog to plant S5a subunit
Probably a bifunctional peroxidase-catalase catalyzing the reaction 2H2O2 = O2 + 2H2O, using heme and manganese as co-factors.
PDS-like 1, phytoene desaturase-like protein, phytoene dehydrogenase-like protein
Phytoene desaturase-like1, expressed gene with similarities to cyanobacterial phytoene desaturases/dehydrogenases, possibly involved in carotenoid biosynthesis
thioredoxin y, contains bipartite plastid targeting presequence with conserved motif at signal peptide cleavage site
protein containing a MCM domain found in DNA-dependent ATPases required for the initiation of eukariotic DNA replication. There is a family of six proteins that interact directly with autonomously replicating sequences. Highly closed to the Thalassiosira protein thaps1 143981.
similar to glucoamylase precursor and cell surface glycoprotein. Glucoamylase breaks 1,4-glycosidic bonds. No interpro domains detected.
protein that contains a DEXHc motif (box helicase) and a HELICc motif (c-terminal domain helicase family).
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase
Possibly catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to Ser or Thr residues.
cytochrome c6, cytochrome c553. Nucleus-encoded. Transfers electrons from cytochrome B6f complex to Photosystem I.
delta 12 desaturase, microsomal membrane-bound. When expressed in yeast, converts exogenous omega-9 oleic acid to omega-6 linoleic acid. Contains three typical 'Histidine-box' motifs. Oxygen-requiring, di-iron binding, oxidoreductase.; nuclear gene for microsomal protein
2,5-diketo-D-gluconic acid reductase A-like protein
Possibly an oxidoreductase (acting on CH-OH donors with NAD+ or NADP+ as acceptor); possibly catalyzes stereospecific reduction of 2,5-diketo-D-gluconate (2,5-DKG) to 2-keto-L-gulonate as a precursor to L-ascorbate (vitamin C) synthesis.
serine hydroxymethyltransferase (glycine hydroxymethyltransferase)catalyzes the conversion of glycine to serine: 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine
transcriptional activator of heat shock genes, located in cytosol/nucleus
short-chain alcohol dehydrogenase with NAD or NADP as acceptor
Possibly a short-chain dehydrogenase/reductase related to alcohol reductase.; +
Annexins are traditionally thought of as calcium-dependent phospholipid-binding proteins
Putative Annexin, strong EST support, Annexin inhibits phopholipase A2 activity and also plays a role in inositol phosphate metabolism, cleaving the cyclic bond of inositol-1,2- cyclic phosphate to yield inositol-1-phosphate.
SMC proteins family involved in structural maintenance of chromosome. Highly closed to the Thalassiosira protein thaps1 23608.
Putative EDS5 which has an essential function in the SA-dependent pathway of plant defense against pathogens and to UV-C stress. As in plants, the protein is predicated to have 8 transmembrane domains. EST coverage unique to decadienal libraries.
dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase
Possibly involved in the synthesis of N-linked glycans in ER-Golgi network. Transfers the first two of three terminal glucosyl residues to the nascent dolichol phosphate-linked core oligosaccharide, which is composed of 3 glucoses, 9 mannoses, and 2 N-acetylglucosamines.
Phosphoribulokinase, chloroplast enzyme, Calvin cycle
Synthesizes glucuronic acid by catalyzing the reaction: UDP-glucose + 2 NAD(+) + H2O = UDP-glucuronic acid + 2 NADH + 2 H(+).
glutathione synthase. glutathione synthetase. GSH synthetase
glutathione synthase, extended N-terminus contains putative ER signal peptide (SignalP score = 0.805), however, this is not predicted by NN, but only HMM. No transit peptide found. Targeting unclear.
small RNA polymerase III subunit of 17 kDa
5'-Nucleotidase or metallophosphoesterase
similarity to 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases - 5'-nucleotidases are enzymes that catalyze the hydrolysis of phosphate esterified at carbon 5' of the ribose and deoxyribose portions of nucleotide molecules; similarity to metallophosphoesterases - metallo-phosphoesterase motif is found in a large number of proteins involved in phosphorylation; contains additional Calcium-binding EF-hand
fucoxanthin chlorophyll a/c protein, lhcf type
A component of a mitochondrial enzyme complex that oxidizes succinate to fumarate in the citric acid cycle. Reaction catalyzed: succinate + ubiquinone = fumarate + ubiquinol. This subunit uses FAD as co-factor.
Rab-family small GTPase, ortholog of T. pseudonana TPS_104375
coproporphyrinogen oxidase. coproporphyrinogen III oxidase. coproporphyrinogenase
eighth step in heme synthesis; although the enzyme is related to chloroplast homologues, no targeting sequences at the N terminus have been found
short chain acyl-coenzyme A dehydrogenase
A short chain acyl-coenzyme A dehydrogenase, located in mitochondria, catalyzes the first step of beta-oxidation of saturated C-C bonds in acyl compounds using FAD as co-factor. Typical reaction catalyzed in butanoate metabolism: butanoyl-CoA + electron transfering flavoprotein = 2-butenoyl-CoA + reduced electron transfering flavoprotein.
enhanced disease susceptibility 5-like protein
An expressed protein with some similarity to enhanced disease suceptibility 5. EDS5 can be induced by salicylic acid, pathogens and UV radiation. Plays an essential function in the salicylic acid-dependent pathway of plant defense against pathogens. Might be part of the functional mechanism for the induction of salicylic acid biosynthesis. Might be a transporter.
DNA gyrase A subunit, highly closed to Thalassiosira protein thaps1 167163.