Zygosaccharomyces rouxii strain CBS732 chromosome G complete sequence.
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Zygosaccharomyces.
Comparative genomics of protoploid Saccharomycetaceae
Submitted (25-SEP-2017) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (04-JUN-2009) Genoscope - Centre National de Sequencage : BP 191 91006 EVRY cedex - FRANCE (E-mail : seqref@genoscope.cns.fr - Web : www.genoscope.cns.fr)
PROVISIONAL REFSEQ: This record has not yet been subject to final\nNCBI review. The reference sequence is identical to CU928179.\nThe Zygosaccharomyces rouxii sequence is made of 7 chromosomes (A\nto G). The sequence was annotated by the Genolevures Consortium.\nFor more information go to\nhttp://cbi.labri.fr/Genolevures.\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: INSDC submitter\nAnnotation Status :: Full annotation\nAnnotation Pipeline :: Eukaryotic Annotation Propagation Pipeline\n##Genome-Annotation-Data-END##
some similarities with uniprot|P36034 Saccharomyces cerevisiae YKL219W COS9
similar to uniprot|P43543 Saccharomyces cerevisiae YNL335W Hypothetical ORF
some similarities with uniprot|Q03034 Saccharomyces cerevisiae YDR539W Hypothetical ORF
similar to uniprot|P53183 Saccharomyces cerevisiae YGL039W and similar to uniprot|P53111 Saccharomyces cerevisiae YGL157W
highly similar to uniprot|P39003 Saccharomyces cerevisiae YDR343C HXT6 High-affinity glucose transporter of the major facilitator superfamily nearly identical to Hxt7p expressed at high basal levels relative to other HXTs repression of expression by high glucose requires SNF3
similar to gnl|GLV|KLLA0C18953g Kluyveromyces lactis KLLA0C18953g and some similarites with YKL015W uniprot|P25502 Saccharomyces cerevisiae YKL015W PUT3 Positive regulator of PUT (proline utilization) genes zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type
highly similar to uniprot|P28273 YKL215C Saccharomyces cerevisiae Hypothetical ORF
weakly similar to uniprot|P53322 Saccharomyces cerevisiae YGR260W
highly similar to uniprot|P38891 Saccharomyces cerevisiae YHR208W BAT1 Mitochondrial branched-chain amino acid aminotransferase homolog of murine ECA39 highly expressed during logarithmic phase and repressed during stationary phase
similar to uniprot|P40099 Saccharomyces cerevisiae YER183C FAU1 5 10-methenyltetrahydrofolate synthetase involved in folic acid biosynthesis
similar to uniprot|P40098 Saccharomyces cerevisiae YER182W FMP10 The authentic non-tagged protein was localized to the mitochondria
similar to uniprot|P38890 Saccharomyces cerevisiae YHR207C SET5
similar to uniprot|P38889 Saccharomyces cerevisiae YHR206W
similar to uniprot|P11792 Saccharomyces cerevisiae YHR205W SCH9 protein kinase involved in growth control may be redundant with cAMP pathway cAMP-dependent protein kinase homolog suppressor of cdc25ts
similar to uniprot|P38888 Saccharomyces cerevisiae YHR204W MNL1 Alpha mannosidase-like protein of the endoplasmic reticulum required for degradation of glycoproteins but not for processing of N-linked oligosaccharides
highly similar to uniprot|P05753 Saccharomyces cerevisiae YJR145C RPS4A or to YHR203C uniprot|P05753 Saccharomyces cerevisiae YHR203C RPS4B
similar to uniprot|P38887 Saccharomyces cerevisiae YHR202W Hypothetical ORF
highly similar to uniprot|Q00684 Saccharomyces cerevisiae YFR028C CDC14 Protein phosphatase required for mitotic exit located in the nucleolus until liberated by the FEAR and Mitotic Exit Network in anaphase enabling it to act on key substrates to effect a decrease in CDK/B-cyclin activity and mitotic exit
similar to uniprot|P43605 Saccharomyces cerevisiae YFR027W ECO1 Acetyltransferase required for the establishment of sister chromatid cohesion during DNA replication but not for its maintenance during G2 and M phases also required for postreplicative double-strand break repair interacts with Chl1p
similar to uniprot|P38635 Saccharomyces cerevisiae YFR025C HIS2 Histidinolphosphatase catalyzes the eighth step in histidine biosynthesis mutations cause histidine auxotrophy and sensitivity to Cu Co and Ni salts transcription is regulated by general amino acid control
highly similar to uniprot|P38708 Saccharomyces cerevisiae YHR020W Protein required for cell viability
similar to uniprot|P38707 Saccharomyces cerevisiae YHR019C DED81 Cytosolic asparaginyl-tRNA synthetase required for protein synthesis catalyzes the specific attachment of asparagine to its cognate tRNA
highly similar to uniprot|P04076 Saccharomyces cerevisiae YHR018C ARG4 Argininosuccinate lyase catalyzes the final step in the arginine biosynthesis pathway
similar to uniprot|P32792 Saccharomyces cerevisiae YHR017W
similar to Saccharomyces cerevisiae YFR024C-A LSB3 or to YHR016C uniprot|P32793 Saccharomyces cerevisiae YHR016C YSC84
similar to uniprot|P39684 Saccharomyces cerevisiae or to YHR015W uniprot|P38760 Saccharomyces cerevisiae
similar to uniprot|P40215 Saccharomyces cerevisiae YMR145C NDE1 Mitochondrial external NADH dehydrogenase
similar to uniprot|Q75BF8 Ashbya gossypii ADL396W ADL396Wp and weakly similar to YNL246W uniprot|P53853 Saccharomyces cerevisiae YNL246W VPS75
similar to uniprot|Q759V0 Ashbya gossypii ADR172C ADR172Cp and weakly similar to YOR018W uniprot|Q02805 Saccharomyces cerevisiae YOR018W ROD1 Membrane protein overexpression confers resistance to the GST substrate o-dinitrobenzene as well as to zinc and calcium contains a PY-motif which is required for Rod1p interaction with Rsp5p a hect-type ubiquitin ligase
similar to uniprot|P43601 Saccharomyces cerevisiae YFR021W ATG18 Phosphatidylinositol 3 5-bisphosphate-binding protein of the vacuolar membrane predicted to fold as a seven-bladed beta-propeller required for recycling of Atg9p through the pre-autophagosomal structure
similar to uniprot|P34756 Saccharomyces cerevisiae YFR019W FAB1 1-phosphatidylinositol-3-phosphate 5-kinase vacuolar membrane kinase that generates phosphatidylinositol (3 5)P2 which is involved in vacuolar sorting and homeostasis
similar to uniprot|P43599 Saccharomyces cerevisiae YFR018C Hypothetical ORF
some similarities with uniprot|Q92325 Saccharomyces cerevisiae YOL025W LAG2 affects longevity involved in determination of longevity
similar to uniprot|P25038 Saccharomyces cerevisiae YOL023W IFM1 Mitochondrial translation initiation factor 2
similar to uniprot|P25040 Saccharomyces cerevisiae YOL022C Protein required for cell viability
highly similar to uniprot|P43535 Saccharomyces cerevisiae YFR009W GCN20 Positive regulator of the Gcn2p kinase activity forms a complex with Gcn1p proposed to stimulate Gcn2p activation by an uncharged tRNA
highly similar to uniprot|Q08162 Saccharomyces cerevisiae YOL021C DIS3 Nucleolar exosome component involved in rRNA processing and RNA degradation binds Gsp1p/Ran and enhances the GEF activity of Srm1p implicated in mitotic control homologous to the E. coli RNase R of the RNase II family
highly similar to uniprot|P43593 Saccharomyces cerevisiae YFR010W UBP6 Ubiquitin-specific protease situated in the base subcomplex of the 26S proteasome releases free ubiquitin from branched polyubiquitin chains deletion causes hypersensitivity to cycloheximide and other toxic compounds
similar to uniprot|P43594 Saccharomyces cerevisiae YFR011C Hypothetical ORF
similar to uniprot|Q03677 Saccharomyces cerevisiae YMR009W ADI1 Predicted acireductone dioxygenease of the methionine salvage pathway
similar to uniprot|Q03687 YMR010W Saccharomyces cerevisiae Protein of unknown function
weakly similar to uniprot|P32606 YOR017W Saccharomyces cerevisiae PET127 Protein with a role in mitochondrial RNA stability and/or processing
similar to uniprot|P23180 Saccharomyces cerevisiae YHL021C FMP12 The authentic non-tagged protein was localized to the mitochondria
similar to uniprot|P23179 Saccharomyces cerevisiae YHL022C SPO11 Meiosis-specific protein that initiates meiotic recombination by catalyzing the formation of double-strand breaks in DNA via a transesterification reaction required for homologous chromosome pairing and synaptonemal complex formation
similar to uniprot|Q12450 Saccharomyces cerevisiae or to uniprot|P39704 Saccharomyces cerevisiae YAL007C ERP2 Protein that forms a heterotrimeric complex with Erp1p, Emp24p, and Erv25p; member, along with Emp24p and Erv25p, of the p24 family involved in ER to Golgi transport and localized to COPII-coated vesicles
weakly similar to uniprot|P18411 Saccharomyces cerevisiae YAL008W
similar to uniprot|P38903 Saccharomyces cerevisiae YOR014W RTS1 B-type regulatory subunit of protein phosphatase 2A (PP2A)
similar to uniprot|Q04170 Saccharomyces cerevisiae YDR391C Hypothetical ORF
similar to uniprot|P32837 Saccharomyces cerevisiae YDL210W UGA4 Permease that serves as a gamma-aminobutyrate (GABA) transport protein involved in the utilization of GABA as a nitrogen source catalyzes the transport of putrescine and delta-aminolevulinic acid (ALA) localized to the vacuolar membrane
similar to uniprot|P18410 Saccharomyces cerevisiae YAL009W SPO7 Integral nuclear/ER membrane protein of unknown function required for normal nuclear envelope morphology and sporulation
similar to uniprot|P18409 Saccharomyces cerevisiae YAL010C MDM10 Subunit of the mitochondrial sorting and assembly machinery (SAM complex) has a role in assembly of the TOM complex which mediates protein import through the outer membrane required for normal mitochondrial morphology and inheritance
some similarities with uniprot|P31376 Saccharomyces cerevisiae YAL011W SWC3 Protein of unknown function component of the Swr1p complex that incorporates Htz1p into chromatin required for formation of nuclear- associated array of smooth endoplasmic reticulum known as karmellae
similar to uniprot|Q08204 Saccharomyces cerevisiae YOL034W SMC5 Structural maintenance of chromosomes (SMC) protein interacts with Rhc18p and Nse1p to form a large complex S. pombe homolog forms a heterodimer with S. pombe Rad18p that is involved in DNA repair
similar to uniprot|Q01476 Saccharomyces cerevisiae YOR124C UBP2 Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins cleaves at the C terminus of ubiquitin fusions capable of cleaving polyubiquitin and possesses isopeptidase activity
highly similar to uniprot|Q06389 Saccharomyces cerevisiae YDR373W FRQ1 N-myristoylated calcium-binding protein that may have a role in intracellular signaling through its regulation of the phosphatidylinositol 4-kinase Pik1p member of the recoverin/frequenin branch of the EF-hand superfamily
highly similar to uniprot|P41735 Saccharomyces cerevisiae YOR125C CAT5 Mitochondrial inner membrane protein directly involved in ubiquinone biosynthesis essential for several other metabolic pathways including respiration and gluconeogenic gene activation
some similarities with uniprot|Q06390 Saccharomyces cerevisiae YDR374C Hypothetical ORF
similar to uniprot|Q2V2P8 Saccharomyces cerevisiae YDR374W-A
highly similar to uniprot|P32839 Saccharomyces cerevisiae YDR375C BCS1 Protein of the mitochondrial inner membrane that functions as an ATP-dependent chaperone required for the assembly of the cytochrome bc(1) complex from the Rip1p and Qcr10p proteins member of the CDC48/PAS1/SEC18 ATPase family
similar to uniprot|P41734 Saccharomyces cerevisiae YOR126C IAH1 Isoamyl acetate-hydrolyzing esterase required in balance with alcohol acetyltransferase to maintain optimal amounts of isoamyl acetate which is particularly important in sake brewing
similar to uniprot|P48360 Saccharomyces cerevisiae YDR376W ARH1 Oxidoreductase of the mitochondrial inner membrane involved in cytoplasmic and mitochondrial iron homeostasis and required for activity of Fe-S cluster-containing enzymes one of the few mitochondrial proteins essential for viability
highly similar to uniprot|Q06405 Saccharomyces cerevisiae YDR377W ATP17 Subunit f of the F0 sector of mitochondrial F1F0 ATP synthase which is a large evolutionarily conserved enzyme complex required for ATP synthesis
some similarities with uniprot|Q06406 Saccharomyces cerevisiae YDR378C LSM6 Component of small nuclear ribonucleoprotein complexes involved in RNA processing splicing and decay
similar to gnl|GLV|KLLA0B13794g Kluyveromyces lactis KLLA0B13794g gi|28565040|gb|AAO32603.1 Kluyveromyces lactis MNN4 hypothetical start KLLA0B13794g|KLLA-IPF6938|KLLA-CDS0444.1 and weakly similar to YKL201C uniprot|P36044 Saccharomyces cerevisiae YKL201C MNN4 Putative positive regulator of mannosylphosphate transferase (Mnn6p) involved in mannosylphosphorylation of N-linked oligosaccharides expression increases in late-logarithmic and stationary growth phases
similar to uniprot|P40354 Saccharomyces cerevisiae YJR062C NTA1 Amidase removes the amide group from N-terminal asparagine and glutamine residues to generate proteins with N-terminal aspartate and glutamate residues that are targets of ubiquitin-mediated degradation
highly similar to uniprot|P32529 Saccharomyces cerevisiae YJR063W RPA12 RNA polymerase I subunit A12.2 contains two zinc binding domains and the N terminal domain is responsible for anchoring to the RNA pol I complex
highly similar to uniprot|P40413 Saccharomyces cerevisiae YJR064W CCT5 Subunit of the cytosolic chaperonin Cct ring complex related to Tcp1p required for the assembly of actin and tubulins in vivo
highly similar to uniprot|P47117 Saccharomyces cerevisiae YJR065C ARP3 Essential component of the Arp2/3 complex which is a highly conserved actin nucleation center required for the motility and integrity of actin patches involved in endocytosis and membrane growth and polarity
highly similar to uniprot|P32600 Saccharomyces cerevisiae YKL203C TOR2 putative protein/phosphatidylinositol kinase involved in signaling activation of translation initiation distribution of the actin cytoskeleton and meiosis phosphatidylinositol kinase homolg
similar to uniprot|P47118 Saccharomyces cerevisiae YJR067C YAE1 Essential protein of unknown function
highly similar to uniprot|P40348 Saccharomyces cerevisiae YJR068W RFC2 Subunit of heteropentameric Replication factor C (RF-C) which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon
weakly similar to uniprot|P36041 Saccharomyces cerevisiae YKL204W EAP1 eIF4E-associated protein binds eIF4E and inhibits cap-dependent translation also functions independently of eIF4E to maintain genetic stability plays a role in cell growth implicated in the TOR signaling cascade
similar to uniprot|P33418 Saccharomyces cerevisiae YKL205W LOS1 Nuclear pore protein involved in nuclear export of pre-tRNA
highly similar to uniprot|P47119 Saccharomyces cerevisiae YJR069C HAM1 Protein of unknown function that is involved in DNA repair mutant is sensitive to the base analog 6-N-hydroxylaminopurine while gene disruption does not increase the rate of spontaneous mutagenesis
highly similar to uniprot|P47120 Saccharomyces cerevisiae YJR070C LIA1 Protein that binds to the C-terminal domain of Hyp2p (eIF5A) has four to five HEAT-like repeats
similar to uniprot|P36040 Saccharomyces cerevisiae YKL206C Hypothetical ORF
highly similar to uniprot|P47122 Saccharomyces cerevisiae YJR072C NPA3 Cytoplasmic protein required for cell viability identified by association with pre-ribosomal particles
similar to uniprot|P36039 Saccharomyces cerevisiae YKL207W Hypothetical ORF
weakly similar to uniprot|P36038 Saccharomyces cerevisiae YKL208W CBT1 Subunit of complex involved in processing of the 3' end of cytochrome b pre-mRNA involved in RNA splicing
similar to uniprot|P05375 Saccharomyces cerevisiae YJR073C OPI3 Phospholipid methyltransferase (methylene-fatty-acyl-phospholipid synthase) catalyzes the last two steps in phosphatidylcholine biosynthesis
similar to uniprot|P12866 Saccharomyces cerevisiae YKL209C STE6 ATP-binding cassette (ABC) transporter required for the export of a-factor catalyzes ATP hydrolysis coupled to a-factor transport contains 12 transmembrane domains and two ATP binding domains expressed only in MATa cells
highly similar to uniprot|P22515 Saccharomyces cerevisiae YKL210W UBA1 Ubiquitin activating enzyme involved in ubiquitin-mediated protein degradation and essential for viability
similar to uniprot|P47123 Saccharomyces cerevisiae YJR074W MOG1 Conserved nuclear protein that interacts with GTP-Gsp1p which is a Ran homolog of the Ras GTPase family and stimulates nucleotide release involved in nuclear protein import nucleotide release is inhibited by Yrb1p
similar to uniprot|P47124 Saccharomyces cerevisiae YJR075W HOC1 Alpha-1 6-mannosyltransferase involved in cell wall mannan biosynthesis subunit of a Golgi-localized complex that also contains Anp1p Mnn9p Mnn11p and Mnn10p identified as a suppressor of a cell lysis sensitive pkc1-371 allele
highly similar to uniprot|P32458 Saccharomyces cerevisiae YJR076C CDC11 Component of the septin ring of the mother-bud neck that is required for cytokinesis septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane and they comprise the 10nm filaments seen with EM
highly similar to uniprot|P00937 Saccharomyces cerevisiae YKL211C TRP3 anthranilate synthase Component II and indole-3-phosphate (multifunctional enzyme)
similar to uniprot|P32368 Saccharomyces cerevisiae YKL212W SAC1 Lipid phosphoinositide phosphatase of the ER and Golgi involved in protein trafficking and secretion
similar to uniprot|P36037 Saccharomyces cerevisiae YKL213C DOA1 WD repeat protein required for ubiquitin-mediated protein degradation forms complex with Cdc48p plays a role in controlling cellular ubiquitin concentration also promotes efficient NHEJ in postdiauxic/stationary phase
some similarities with uniprot|P36036 Saccharomyces cerevisiae YKL214C YRA2 Member of the REF (RNA and export factor binding proteins) family when overexpressed can substitute for the function of Yra1p in export of poly(A) mRNA from the nucleus
similar to uniprot|Q0P727 Saccharomyces paradoxus HDF2 HDF2 protein
highly similar to uniprot|P37012 Saccharomyces cerevisiae YMR105C PGM2 Phosphoglucomutase catalyzes the conversion from glucose-1-phosphate to glucose-6-phosphate which is a key step in hexose metabolism functions as the acceptor for a Glc-phosphotransferase and to YKL127W uniprot|P33401 Saccharomyces cerevisiae YKL127W PGM1 Phosphoglucomutase, minor isoform; catalyzes the conversion from glucose-1-phosphate to glucose-6- phosphate, which is a key step in hexose metabolism
highly similar to uniprot|P12688 Saccharomyces cerevisiae YKL126W and highly similar to uniprot|P18961 Saccharomyces cerevisiae YMR104C
some similarities with uniprot|P36070 Saccharomyces cerevisiae YKL125W RRN3 Required for transcription of rDNA by RNA Polymerase I DNA-independent RNA Polymerase I transcription factor
similar to uniprot|P32343 Saccharomyces cerevisiae YKL124W SSH4 Suppressor of SHR3 confers leflunomide resistance when overexpressed (putative) involved in ER functions
similar to uniprot|P32342 Saccharomyces cerevisiae YKL122C SRP21 Component of the signal recognition particle (SRP) ribonucleoprotein (RNP) complex that functions in protein targeting to the endoplasmic reticulum (ER) membrane
similar to uniprot|Q03177 Saccharomyces cerevisiae YMR102C Protein of unknown function transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance
similar to uniprot|P32332 Saccharomyces cerevisiae YKL120W OAC1 Mitochondrial inner membrane transporter transports oxaloacetate sulfate and thiosulfate member of the mitochondrial carrier family
similar to uniprot|Q03175 Saccharomyces cerevisiae YMR101C SRT1 Cis-prenyltransferase involved in dolichol synthesis
similar to uniprot|P32341 Saccharomyces cerevisiae YKL119C VPH2 Protein involved in vacuolar H -ATPase assembly or function required for the biogenesis of a functional vacuolar ATPase (V-ATPase) but not part of the final enzyme complex
similar to uniprot|Q03162 Saccharomyces cerevisiae YMR100W
similar to uniprot|Q82BJ9 Streptomyces avermitilis SAV5706 Hypothetical protein
similar to uniprot|P28707 Saccharomyces cerevisiae YKL117W
highly similar to uniprot|Q03161 Saccharomyces cerevisiae YMR099C ORF
similar to uniprot|P28708 Saccharomyces cerevisiae YKL116C PRR1 Protein kinase with a possible role in MAP kinase signaling in the pheromone response pathway
highly similar to uniprot|P22936 Saccharomyces cerevisiae YKL114C APN1 Major apurinic/apyrimidinic endonuclease 3'-repair diesterase involved in repair of DNA damage by oxidation and alkylating agents controls spontaneous mutations
highly similar to uniprot|P26793 Saccharomyces cerevisiae YKL113C RAD27 5' to 3' exonuclease 5' flap endonuclease required for Okazaki fragment processing and maturation as well as for long-patch base-excision repair member of the S. pombe RAD2/FEN1 family
similar to uniprot|P12630 Saccharomyces cerevisiae YIL015W BAR1 Aspartyl protease secreted into the periplasmic space of mating type a cells, cleaves and inactivates alpha factor allowing cells to recover from alpha-factor-induced cell cycle arrest and to YLR121C uniprot|Q12303 Saccharomyces cerevisiae YLR121C YPS3 Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor and to YLR120C uniprot|P32329 Saccharomyces cerevisiae YLR120C YPS1 Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor and to YDR144C uniprot|P53379 Saccharomyces cerevisiae YDR144C MKC7 GPI-anchored aspartyl protease (yapsin) involved in protein processing; shares functions with Yap3p and Kex2p and to YIR039C uniprot|P40583 Saccharomyces cerevisiae YIR039C YPS6 Putative GPI-anchored aspartic protease, member on vGLC.1466.
some similarities with uniprot|P14164 Saccharomyces cerevisiae YKL112W ABF1 DNA binding protein with possible chromatin-reorganizing activity involved in transcriptional activation gene silencing and DNA replication and repair
similar to uniprot|Q03153 Saccharomyces cerevisiae YMR098C Hypothetical ORF
similar to uniprot|P34253 Saccharomyces cerevisiae YKL110C KTI12 Protein associated with the RNA polymerase II Elongator complex involved in sensitivity to G1 arrest induced by Kluyveromyces lactis toxin zymocin
similar to uniprot|Q03151 Saccharomyces cerevisiae YMR097C MTG1 Peripheral GTPase of the mitochondrial inner membrane essential for respiratory competence likely functions in assembly of the large ribosomal subunit has homologs in plants and animals
weakly similar to uniprot|P41902 Saccharomyces cerevisiae YOR031W CRS5 Copper-binding metallothionein required for wild-type copper resistance
highly similar to uniprot|P43545 Saccharomyces cerevisiae YFL059W SNZ3 Member of a stationary phase-induced gene family transcription of SNZ2 is induced prior to diauxic shift and also in the absence of thiamin in a Thi2p-dependent manner forms a coregulated gene pair with SNO3 and uniprot|P53824 Saccharomyces cerevisiae YNL333W SNZ2 and YMR096W uniprot|Q03148 Saccharomyces cerevisiae YMR096W SNZ1
similar to uniprot|P43544 Saccharomyces cerevisiae YFL060C SNO3 Protein of unknown function nearly identical to Sno2p expression is induced before the diauxic shift and also in the absence of thiamin and uniprot|P53823 Saccharomyces cerevisiae YNL334C SNO2 and uniprot|Q03144 Saccharomyces cerevisiae YMR095C SNO1
similar to uniprot|P35203 Saccharomyces cerevisiae YMR094W CTF13 Subunit of the CBF3 complex which binds to the CDE III element of centromeres bending the DNA upon binding and may be involved in sister chromatid cohesion during mitosis
similar to uniprot|Q75DR2 Ashbya gossypii ABL045W ABL045Wp and weakly similar to YKL108W uniprot|P34252 Saccharomyces cerevisiae YKL108W SLD2 Protein required for DNA replication phosphorylated in S phase by S-phase cyclin-dependent kinases (Cdks) phosphorylation is essential for DNA replication and for complex formation with Dpb11p potential Cdc28p substrate
highly similar to uniprot|Q04305 Saccharomyces cerevisiae YMR093W UTP15 Nucleolar protein component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
similar to uniprot|P46680 Saccharomyces cerevisiae YMR092C AIP1 Actin cortical patch component probable binding site on actin lies on front surface of subdomains 3 and 4
similar to uniprot|P32832 Saccharomyces cerevisiae YMR091C NPL6 Nuclear protein that may have a role in nuclear protein import
similar to uniprot|P40341 Saccharomyces cerevisiae YMR089C YTA12 Component with Afg3p of the mitochondrial inner membrane m-AAA protease that mediates degradation of misfolded or unassembled proteins and is also required for correct assembly of mitochondrial enzyme complexes
similar to uniprot|Q04301 Saccharomyces cerevisiae YMR088C VBA1 Permease of basic amino acids in the vacuolar membrane
similar to uniprot|Q04299 Saccharomyces cerevisiae YMR087W Putative ADP-ribose-1''-monophosphatase that converts ADP-ribose-1''-monophosphate to ADP-ribose may have a role in tRNA splicing contains an A1pp domain
similar to uniprot|Q01802 Saccharomyces cerevisiae YKL106W AAT1 Mitochondrial aspartate aminotransferase catalyzes the conversion of oxaloacetate to aspartate in aspartate and asparagine biosynthesis
some similarities with uniprot|Q04279 Saccharomyces cerevisiae YMR086W Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
highly similar to uniprot|P14742 Saccharomyces cerevisiae YKL104C GFA1 Glutamine-fructose-6-phosphate amidotransferase catalyzes the formation of glucosamine-6-P and glutamate from fructose-6-P and glutamine in the first step of chitin biosynthesis
similar to uniprot|P14904 YKL103C Saccharomyces cerevisiae LAP4 Vacuolar aminopeptidase
similar to uniprot|P34244 Saccharomyces cerevisiae YKL101W HSL1 Nim1p-related protein kinase that regulates the morphogenesis and septin checkpoints associates with the assembled septin filament required along with Hsl7p for bud neck recruitment phosphorylation and degradation of Swe1p
similar to uniprot|P07246 Saccharomyces cerevisiae YMR083W
similar to uniprot|P07246 Saccharomyces cerevisiae YMR083W ADH3
some similarities with uniprot|P32945 Saccharomyces cerevisiae YPL179W PPQ1 Putative protein serine/threonine phosphatase null mutation enhances efficiency of translational suppressors
weakly similar to uniprot|Q6B1X3 Saccharomyces cerevisiae YPL181W CTI6 Protein that relieves transcriptional repression by binding to the Cyc8p-Tup1p corepressor and recruiting the SAGA complex to the repressed promoter contains a PHD finger domain
similar to uniprot|P38932 Saccharomyces cerevisiae YGL095C VPS45 Protein of the Sec1p family essential for vacuolar protein sorting required for the function of both Pep12p and the early endosome/late Golgi SNARE Tlg2p
similar to uniprot|Q08921 Saccharomyces cerevisiae YPL180W TCO89 Tor Complex One
similar to uniprot|P53010 Saccharomyces cerevisiae YGL094C PAN2 Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex which acts to control poly(A) tail length and regulate the stoichiometry and activity of postreplication repair complexes
similar to uniprot|Q08924 Saccharomyces cerevisiae YPL183C Hypothetical ORF
similar to uniprot|Q07843 Saccharomyces cerevisiae YLL033W
similar to uniprot|Q07834 Saccharomyces cerevisiae YLL032C Hypothetical ORF
similar to uniprot|P28321 Saccharomyces cerevisiae YKL094W YJU3 Protein of unknown function localizes to lipid particles
similar to uniprot|P30771 Saccharomyces cerevisiae YMR080C NAM7 ATP-dependent RNA helicase of the SFI superfamily required for nonsense mediated mRNA decay and for efficient translation termination at nonsense codons
similar to uniprot|P33314 Saccharomyces cerevisiae YKL092C BUD2 GTPase activating factor for Rsr1p/Bud1p required for both axial and bipolar budding patterns mutants exhibit random budding in all cell types
highly similar to uniprot|P24280 Saccharomyces cerevisiae YMR079W SEC14 Phosphatidylinositol/phosphatidylcholine transfer protein involved in coordinate regulation of PtdIns and PtdCho metabolism products of which are regulators in Golgi to plasma membrane transport functionally homologous to mammalian PITPs
similar to uniprot|P49956 Saccharomyces cerevisiae YMR078C CTF18 Subunit of a complex with Ctf8p that shares some subunits with Replication Factor C and is required for sister chromatid cohesion may have overlapping functions with Rad24p in the DNA damage replication checkpoint
similar to uniprot|Q04272 Saccharomyces cerevisiae YMR077C VPS20 vaculolar protein sorting (putative)
similar to gnl|GLV|CAGL0J01936g Candida glabrata CAGL0J01936g and some similarites with uniprot|P40564 YIR004W Saccharomyces cerevisiae DJP1 Cytosolic J-domain-containing protein, required for peroxisomal protein import
some similarities with uniprot|P40563 Saccharomyces cerevisiae YIR003W Hypothetical ORF
highly similar to uniprot|P33331 Saccharomyces cerevisiae YER009W NTF2 Nuclear envelope protein interacts with GDP-bound Gsp1p and with proteins of the nuclear pore to transport Gsp1p into the nucleus where it is an essential player in nucleocytoplasmic transport
weakly similar to uniprot|P33332 YER008C Saccharomyces cerevisiae SEC3 Non-essential subunit of the exocyst complex (Sec3p Sec5p Sec6p Sec8p Sec10p Sec15p Exo70p Exo84p)
similar to uniprot|P40562 YIR002C Saccharomyces cerevisiae MPH1 Member of the DEAH family of helicases
some similarities with uniprot|P32521 YIR006C Saccharomyces cerevisiae PAN1 Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p
similar to uniprot|P40565 YIR005W Saccharomyces cerevisiae IST3 Component of the U2 snRNP required for the first catalytic step of splicing and for spliceosomal assembly
similar to uniprot|P40011 Saccharomyces cerevisiae YER010C Hypothetical ORF
similar to uniprot|P40549 Saccharomyces cerevisiae YIL014W MNT3 Alpha-1 3-mannosyltransferase adds the fourth and fifth alpha-1 3-linked mannose residues to O-linked glycans during protein O-glycosylation
weakly similar to uniprot|P40573 Saccharomyces cerevisiae YIR017C MET28 Transcriptional activator in the Cbf1p-Met4p-Met28p complex participates in the regulation of sulfur metabolism
some similarities with uniprot|Q08206 Saccharomyces cerevisiae YOL036W Protein of unknown function potential Cdc28p substrate
highly similar to uniprot|P40303 Saccharomyces cerevisiae YOL038W PRE6 20S proteasome alpha-type subunit
some similarities with uniprot|Q08176 Saccharomyces cerevisiae YOL026C MIM1 Mitochondrial outer membrane protein that mediates assembly of mitochondrial beta-barrel proteins also proposed to be involved in mitochondrial import
similar to uniprot|P40571 Saccharomyces cerevisiae YIR015W RPR2 Subunit of nuclear RNase P which cleaves tRNA precursors to generate mature 5' ends not shared between Rnase MRP and Rnase P in contrast to all other Rnase P protein subunits
weakly similar to uniprot|P40570 Saccharomyces cerevisiae YIR014W Hypothetical ORF
some similarites with uniprot|Q08179 Saccharomyces cerevisiae YOL027C MDM38 Mitochondrial Distribution and Morphology
similar to uniprot|P40574 Saccharomyces cerevisiae YIR018W YAP5 bZIP transcription factor
similar to uniprot|Q08193 Saccharomyces cerevisiae YOL030W GAS5 Putative 1,3-beta-glucanosyltransferase has similarity to Gas1p localizes to the cell wall
weakly similar to uniprot|Q08157 Saccharomyces cerevisiae YOL019W Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and vacuole
similar to uniprot|Q08144 Saccharomyces cerevisiae YOL018C TLG2 member of the syntaxin family of t-SNAREs
weakly similar to uniprot|Q92274 Saccharomyces cerevisiae YOR129C Putative component of the outer plaque of the spindle pole body may be involved in cation homeostasis or multidrug resistance
similar to uniprot|Q06408 Saccharomyces cerevisiae YDR380W ARO10 Phenylpyruvate decarboxylase catalyzes decarboxylation of phenylpyruvate to phenylacetaldehyde which is the first specific step in the Ehrlich pathway
uniprot|Q9UVE6 Zygosaccharomyces rouxii ade2 Phosphoribosylaminoimidazole carboxylase
highly similar to uniprot|Q3E785 Saccharomyces cerevisiae YDR379C-A Hypothetical ORF
uniprot|Q9P8F2 Zygosaccharomyces rouxii rga1 Pheromone response protein
some similarities with uniprot|P17106 Saccharomyces cerevisiae YJR060W CBF1 Helix-loop-helix protein that binds the motif CACRTG (R
similar to uniprot|P47116 Saccharomyces cerevisiae YJR059W PTK2 Putative serine/threonine protein kinase involved in regulation of ion transport across plasma membrane enhances spermine uptake
similar to uniprot|P24004 Saccharomyces cerevisiae YKL197C PEX1 AAA-family ATPase peroxin required for peroxisome biogenesis contains two 230 amino acid ATP-binding AAA cassettes upregulated in anaerobiosis Pex1p and Pex6p interact via their N-terminal AAA-cassettes
highly similar to uniprot|Q00381 Saccharomyces cerevisiae YJR058C APS2 Small subunit of the clathrin-associated adaptor complex AP-2 which is involved in protein sorting at the plasma membrane related to the sigma subunit of the mammalian plasma membrane clathrin-associated protein (AP-2) complex
similar to uniprot|P00572 Saccharomyces cerevisiae YJR057W CDC8 Thymidylate and uridylate kinase functions in de novo biosynthesis of pyrimidine deoxyribonucleotides converts dTMP to dTDP and dUMP to dUTP essential for mitotic and meiotic DNA replication homologous to S. pombe Tmp1p
similar to uniprot|P47115 Saccharomyces cerevisiae YJR056C Hypothetical ORF
weakly similar to uniprot|P54003 Saccharomyces cerevisiae YML052W SUR7
similar to uniprot|P04387 Saccharomyces cerevisiae YML051W GAL80 Transcriptional regulator involved in the repression of GAL genes in the absence of galactose inhibits transcriptional activation by Gal4p inhibition relieved by Gal3p or Gal1p binding
similar to uniprot|P46973 Saccharomyces cerevisiae YJR055W HIT1 Protein of unknown function required for growth at high temperature
similar to uniprot|Q04689 Saccharomyces cerevisiae YML050W Hypothetical ORF
similar to uniprot|Q04693 Saccharomyces cerevisiae YML049C RSE1 RNA splicing and ER to Golgi transport involved in secretion and RNA splicing
similar to uniprot|Q04697 Saccharomyces cerevisiae YML048W GSF2 ER localized integral membrane protein that may promote secretion of certain hexose transporters including Gal2p involved in glucose-dependent repression
some similarities with uniprot|P47114 Saccharomyces cerevisiae YJR054W Vacuolar protein of unknown function potential Cdc28p substrate
similar to uniprot|P47113 Saccharomyces cerevisiae YJR053W BFA1 Component of the GTPase-activating Bfa1p-Bub2p complex involved in multiple cell cycle checkpoint pathways that control exit from mitosis
similar to uniprot|P39682 Saccharomyces cerevisiae YML046W PRP39 U1 snRNP protein involved in splicing contains multiple tetriatricopeptide repeats
highly similar to gnl|GLV|CAGL0J11154g Candida glabrata CAGL0J11154g and similar to YNL175C uniprot|P53883 Saccharomyces cerevisiae
some similarities with uniprot|P38845 Saccharomyces cerevisiae YHR146W CRP1 Protein that binds to cruciform DNA structures
similar to uniprot|P53886 Saccharomyces cerevisiae YNL172W APC1 Largest subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors including mitotic cyclins during the metaphase/anaphase transition
highly similar to uniprot|P39006 Saccharomyces cerevisiae YNL169C PSD1 Phosphatidylserine decarboxylase of the mitochondrial inner membrane converts phosphatidylserine to phosphatidylethanolamine
similar to uniprot|P06773 Saccharomyces cerevisiae YHR144C DCD1 Deaminase required for dCTP and dTTP synthesis expression is cell cycle regulated
highly similar to uniprot|P53889 Saccharomyces cerevisiae YNL168C FMP41 The authentic non-tagged protein was localized to mitochondria
some similarities with uniprot|Q02100 Saccharomyces cerevisiae YNL167C SKO1 Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family that forms a complex with Tup1p and Ssn6p to both activate and repress transcription cytosolic and nuclear protein involved in the osmotic and oxidative stress responses
highly similar to uniprot|P40422 Saccharomyces cerevisiae YHR143W-A RPC10 RNA polymerase subunit ABC10-alpha common to RNA polymerases I II and III
similar to uniprot|P53890 Saccharomyces cerevisiae YNL166C BNI5 Protein involved in organization of septins at the mother-bud neck may interact directly with the Cdc11p septin localizes to bud neck in a septin-dependent manner
similar to uniprot|P53891 Saccharomyces cerevisiae YNL165W Hypothetical ORF
some similarities with uniprot|P38844 Saccharomyces cerevisiae YHR143W
some similarities with uniprot|P53892 Saccharomyces cerevisiae YNL164C IBD2 Component of the BUB2-dependent spindle checkpoint pathway interacts with Bfa1p and functions upstream of Bub2p and Bfa1p
similar to uniprot|P53893 Saccharomyces cerevisiae YNL163C
highly similar to uniprot|P38843 Saccharomyces cerevisiae YHR142W CHS7
highly similar to uniprot|P02405 Saccharomyces cerevisiae YHR141C RPL42B Proteins component of the large (60S) ribosomal subunit
some similarities with uniprot|P53894 Saccharomyces cerevisiae YNL161W CBK1 Protein kinase involved in cell wall biosynthesis required for efficient apical growth proper mating projection morphology bipolar bud site selection in diploid cells and cell separation
similar to uniprot|P38842 Saccharomyces cerevisiae YHR140W Hypothetical ORF
weakly similar to uniprot|P38616 Saccharomyces cerevisiae YNL160W YGP1 may be involved in cellular adaptations prior to stationary phase YGP1 encodes gp37 a glycoprotein synthesized in response to nutrient limitation which is homologous to the sporulation-specific SPS100 gene
similar to uniprot|P41948 Saccharomyces cerevisiae YNL142W MEP2 Ammonium permease involved in regulation of pseudohyphal growth belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4) expression is under the nitrogen catabolite repression regulation
similar to uniprot|P38841 Saccharomyces cerevisiae YHR138C Homologous to PBI2
highly similar to uniprot|P53900 Saccharomyces cerevisiae YNL153C GIM3 Subunit of the heterohexameric cochaperone prefoldin complex which binds specifically to cytosolic chaperonin and transfers target proteins to it
similar to uniprot|P38840 Saccharomyces cerevisiae YHR137W ARO9 Aromatic aminotransferase catalyzes the first step of tryptophan phenylalanine and tyrosine catabolism
highly similar to uniprot|P53909 Saccharomyces cerevisiae YNL141W AAH1 Adenine deaminase (adenine aminohydrolase) involved in purine salvage and nitrogen catabolism
similar to uniprot|P23292 Saccharomyces cerevisiae YNL154C YCK2 membrane-bound casein kinase I homolog
similar to uniprot|P53899 Saccharomyces cerevisiae YNL155W Hypothetical ORF
similar to uniprot|P38838 Saccharomyces cerevisiae YHR134W WSS1 weak suppressor of smt3
similar to uniprot|P53898 Saccharomyces cerevisiae YNL156C NSG2 Protein of unknown function potential homolog of mammalian Insig 1
highly similar to uniprot|Q9P305 Saccharomyces cerevisiae YHR132W-A Hypothetical ORF
similar to uniprot|P38836 Saccharomyces cerevisiae YHR132C
similar to uniprot|P53896 Saccharomyces cerevisiae YNL158W Essential protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery
similar to uniprot|P53895 Saccharomyces cerevisiae YNL159C ASI2 Predicted membrane protein genetic interactions suggest a role in negative regulation of amino acid uptake
some similarities with uniprot|P00812 Saccharomyces cerevisiae YPL111W
similar to uniprot|P38835 Saccharomyces cerevisiae YHR131C Hypothetical ORF
similar to uniprot|P38696 Saccharomyces cerevisiae YHR129C ARP1 Actin-related protein of the dynactin complex required for spindle orientation and nuclear migration putative ortholog of mammalian centractin
highly similar to uniprot|P18562 Saccharomyces cerevisiae YHR128W FUR1 Uracil phosphoribosyltransferase synthesizes UMP from uracil involved in the pyrimidine salvage pathway
highly similar to uniprot|P53905 Saccharomyces cerevisiae YNL147W LSM7 Component of small nuclear ribonucleoprotein complexes involved in RNA processing splicing and decay
similar to uniprot|Q754L8 Ashbya gossypii AFR054W AFR054Wp and weakly similar to YNL148C uniprot|P53904 Saccharomyces cerevisiae YNL148C ALF1 alpha-tubulin foldin protein implicated in folding of alpha tubulin cofactor B
similar to gnl|GLV|KLLA0A11506g Kluyveromyces lactis KLLA0A11506g and weakly similar to YNL149C uniprot|P53903 Saccharomyces cerevisiae YNL149C Protein required for cell viability
similar to uniprot|P17890 Saccharomyces cerevisiae YNL151C RPC31 RNA polymerase III subunit C31 contains HMG-like C-terminal domain
similar to uniprot|P53901 Saccharomyces cerevisiae YNL152W Protein required for cell viability
similar to uniprot|P53552 Saccharomyces cerevisiae YNL139C RLR1 Required for LacZ RNA expression from certain plasmids suppressor of the Transcriptional (T) defect of Hpr1 (H) by Overexpression (O) plays a role in transcription elongation by RNA polymerase II Involved in transcription
similar to uniprot|P0C074 Saccharomyces cerevisiae YNL138W-A RCP10 Component of the U2 snRNP associated with the SF3b complex conserved in Ashbya gossypii
similar to gnl|GLV|CAGL0H09086g Candida glabrata CAGL0H09086g and some similarites with YHR127W uniprot|P38833 Saccharomyces cerevisiae YHR127W (H)igh copy (S)uppressor of (N)34 dominant negative allele of SEC4. Suppression is very specific to this allele. It has no affect on the analogous YPT1 allele. No homology or known function.
similar to uniprot|P17555 Saccharomyces cerevisiae YNL138W SRV2 Adenylyl cyclase-associated protein N-terminal domain appears to be involved in cellular responsiveness to RAS
mitochondrial 37S ribosomal protein NAM9
similar to uniprot|P27929 Saccharomyces cerevisiae YNL137C NAM9 Mitochondrial ribosomal component of the small subunit
some similarities with uniprot|P53911 Saccharomyces cerevisiae YNL136W EAF7 Subunit of the NuA4 histone acetyltransferase complex which acetylates the N-terminal tails of histones H4 and H2A
highly similar to uniprot|P20081 Saccharomyces cerevisiae YNL135C FPR1 Peptidyl-prolyl cis-trans isomerase (PPIase) binds to the drugs FK506 and rapamycin also binds to the nonhistone chromatin binding protein Hmo1p and may regulate its assembly or function
similar to uniprot|P53912 Saccharomyces cerevisiae YNL134C
some similarities with uniprot|P38830 Saccharomyces cerevisiae YHR124W NDT80 Meiosis-specific transcription factor required for exit from pachytene and for full meiotic recombination activates middle sporulation genes competes with Sum1p for binding to promoters containing middle sporulation elements (MSE)
highly similar to uniprot|P53914 Saccharomyces cerevisiae YNL132W KRE33 Essential protein of unknown function heterozygous mutant shows haploinsufficiency in K1 killer toxin resistance
similar to uniprot|P49334 Saccharomyces cerevisiae YNL131W TOM22 Translocase of Outer Mitochondrial membrane Mitochondrial import receptor complex protein
similar to uniprot|P17898 Saccharomyces cerevisiae YNL130C CPT1 and similar to uniprot|P22140 Saccharomyces cerevisiae YHR123w Cholinephosphotransferase
similar to uniprot|P38829 Saccharomyces cerevisiae YHR122W Protein required for cell viability
similar to uniprot|P53915 Saccharomyces cerevisiae YNL129W
uniprot|Q6RI82 Zygosaccharomyces rouxii TEP1 TEP1 protein
uniprot|Q6RI83 Zygosaccharomyces rouxii similar to YHR121W uniprot|P38828 Saccharomyces cerevisiae YHR121W LSM12 Protein containing an Lsm domain and an AD domain may bind RNA and have a role in RNA processing
similar to uniprot|P53917 Saccharomyces cerevisiae YNL127W FAR11 Protein involved in G1 cell cycle arrest in response to pheromone in a pathway different from the Far1p-dependent pathway interacts with Far3p Far7p Far8p Far9p and Far10p
similar to uniprot|P53540 Saccharomyces cerevisiae YNL126W SPC98 Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex interacts with Spc110p at the spindle pole body (SPB) inner plaque and with Spc72p at the SPB outer plaque
some similarities with uniprot|P53918 Saccharomyces cerevisiae YNL125C ESBP6 Protein with similarity to monocarboxylate permeases appears not to be involved in transport of monocarboxylates such as lactate pyruvate or acetate across the plasma membrane
some similarities with uniprot|P53919 Saccharomyces cerevisiae YNL124W
similar to uniprot|P25846 Saccharomyces cerevisiae YHR120W MSH1 DNA-binding protein of the mitochondria involved in repair of mitochondrial DNA has ATPase activity and binds to DNA mismatches has homology to E. coli MutS transcription is induced during meiosis
similar to uniprot|P38827 Saccharomyces cerevisiae YHR119W SET1 Histone methyltransferase subunit of the COMPASS complex which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres contains a SET domain
similar to uniprot|P38826 Saccharomyces cerevisiae YHR118C ORC6 Subunit of the origin recognition complex which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing may be phosphorylated by Cdc28p
similar to uniprot|Q75D91 Ashbya gossypii ABR133W 50S ribosomal protein L35 and some similarites with YNL122C uniprot|P53921 Saccharomyces cerevisiae YNL122C Hypothetical ORF
similar to uniprot|P07213 Saccharomyces cerevisiae YNL121C TOM70 Translocase of Outer Mitochondrial membrane 70 kDa mitochondrial specialized import receptor of the outer membrane
similar to uniprot|P38824 Saccharomyces cerevisiae YHR116W COX23 Mitochondrial intermembrane space protein that functions in mitochondrial
similar to uniprot|P32354 Saccharomyces cerevisiae YIL150C MCM10 Essential chromatin-associated protein involved in the initiation of DNA replication required for the association of the MCM2-7 complex with replication origins
some similarities with uniprot|Q02455 Saccharomyces cerevisiae YKR095W MLP1 Myosin-like protein associated with the nuclear envelope, connects the nuclear pore complex with the nuclear interior; involved in the Tel1p pathway that controls telomere length; involved in the retention of unspliced mRNAs in the nucleus
ubiquitin-60S ribosomal protein L40 fusion protein
highly similar to uniprot|P14796 Saccharomyces cerevisiae YKR094C RPL40B
similar to uniprot|P39928 Saccharomyces cerevisiae YIL147C SLN1 Histidine kinase osmosensor that regulates a MAP kinase cascade; transmembrane protein with an intracellular kinase domain that signals to Ypd1p and Ssk1p, thereby forming a phosphorelay system similar to bacterial two-component regulators
similar to uniprot|P40458 Saccharomyces cerevisiae YIL146C ECM37 Non-essential protein of unknown function
similar to uniprot|P32901 Saccharomyces cerevisiae YKR093W PTR2 Functions in transport of small peptides into the cell Peptide transporter
similar to uniprot|P40459 Saccharomyces cerevisiae YIL145C PAN6 Pantothenate synthase also known as pantoate-beta-alanine ligase required for pantothenic acid biosynthesis deletion causes pantothenic acid auxotrophy homologous to E. coli panC
highly similar to gnl|GLV|CAGL0G05291g Candida glabrata CAGL0G05291g and similar to YDR071C uniprot|Q12447 Saccharomyces cerevisiae YDR071C PAA1 Polyamine acetyltransferase acetylates polyamines such as putrescine spermidine and spermine may be involved in transcription initiation
similar to uniprot|Q12497 Saccharomyces cerevisiae YDR070C FMP16 The authentic non-tagged protein was localized to the mitochondria
some similarities with uniprot|P32571 Saccharomyces cerevisiae YDR069C DOA4 Ubiquitin hydrolase required for recycling ubiquitin from proteasome-bound ubiquitinated intermediates acts at the late endosome/prevacuolar compartment to recover ubiquitin from ubiquitinated membrane proteins en route to the vacuole
similar to uniprot|P54858 Saccharomyces cerevisiae YDR068W DOS2 Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm
similar to uniprot|Q6Q559 Saccharomyces cerevisiae YDR067C which is a model system for studying replication of positive-strand RNA viruses in their natural hosts
similar to uniprot|P40087 Saccharomyces cerevisiae YER143W DDI1 DNA damage-inducible v-SNARE binding protein contains a ubiquitin-associated (UBA) domain may act as a negative regulator of constitutive exocytosis may play a role in S-phase checkpoint control
similar to uniprot|P22134 Saccharomyces cerevisiae YER142C MAG1 3-methyl-adenine DNA glycosylase involved in protecting DNA against alkylating agents initiates base excision repair by removing damaged bases to create abasic sites that are subsequently repaired
similar to uniprot|P40086 Saccharomyces cerevisiae YER141W COX15 Protein required for the hydroxylation of heme O to form heme A which is an essential prosthetic group for cytochrome c oxidase
similar to uniprot|P40085 Saccharomyces cerevisiae YER140W Hypothetical ORF
similar to uniprot|P40084 Saccharomyces cerevisiae YER139C Hypothetical ORF
similar to uniprot|Q6Q5U4 Saccharomyces cerevisiae YDR065W Hypothetical ORF
similar to uniprot|P13856 Saccharomyces cerevisiae YGR152C RSR1 GTP-binding protein of the ras superfamily required for bud site selection, morphological changes in response to mating pheromone, and efficient cell fusion; localized to the plasma membrane; significantly similar to mammalian Rap GTPases
similar to gnl|GLV|KLLA0C12023g Kluyveromyces lactis KLLA0C12023g and some similarites with YGL105W uniprot|P46672 Saccharomyces cerevisiae YGL105W ARC1 Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases (Mes1p and Gus1p) delivering tRNA to them stimulating catalysis and ensuring their localization to the cytoplasm also binds quadruplex nucleic acids
highly similar to uniprot|P05373 Saccharomyces cerevisiae YGL040C HEM2 Delta-aminolevulinate dehydratase a homo-octameric enzyme catalyzes the conversion of delta-aminolevulinic acid to porphobilinogen the second step in the heme biosynthetic pathway localizes to both the cytoplasm and nucleus
highly similar to uniprot|P32582 Saccharomyces cerevisiae YGR155W CYS4 Cystathionine beta-synthase catalyzes the synthesis of cystathionine from serine and homocysteine the first committed step in cysteine biosynthesis
similar to uniprot|P0C5N3 Saccharomyces cerevisiae YGL041W-A Identified by expression profiling and mass spectrometry
highly similar to gnl|GLV|CAGL0D06160g Candida glabrata CAGL0D06160g and similar to uniprot|P07273 YGL043W Saccharomyces cerevisiae DST1 General transcription elongation factor TFIIS
similar to uniprot|P25299 Saccharomyces cerevisiae YGL044C RNA15 Cleavage and polyadenylation factor I (CF I) component involved in cleavage and polyadenylation of mRNA 3' ends interacts with the A-rich polyadenylation signal in complex with Rna14p and Hrp1p
some similarities with uniprot|P39927 Saccharomyces cerevisiae YGR156W PTI1 Pta1p Interacting protein
similar to uniprot|P05374 Saccharomyces cerevisiae YGR157W CHO2 First step in the methylation pathway for phosphatidylcholine biosynthesis Phosphatidyl-ethanolamine N-methyltransferase
similar to uniprot|P48240 Saccharomyces cerevisiae YGR158C MTR3 3'5' exoribonuclease exosome subunit nucleolar protein involved in export of mRNA and ribosomal subunits homologous to the E. coli exonuclease RNase PH
similar to uniprot|P53180 Saccharomyces cerevisiae YGL045W RIM8
some similarities with uniprot|P27476 Saccharomyces cerevisiae YGR159C NSR1 Nucleolar protein that binds nuclear localization sequences required for pre-rRNA processing and ribosome biogenesis
some similarities with uniprot|P53289 Saccharomyces cerevisiae YGR161C RTS3 Hypothetical ORF
similar to uniprot|P53746 Saccharomyces cerevisiae YNR060W FRE4 Ferric reductase reduces a specific subset of siderophore-bound iron prior to uptake by transporters expression induced by low iron levels
similar to uniprot|P38731 Saccharomyces cerevisiae YHL040C ARN1 Transporter member of the ARN family of transporters that specifically recognize siderophore-iron chelates responsible for uptake of iron bound to ferrirubin ferrirhodin and related siderophores
similar to uniprot|P38732 Saccharomyces cerevisiae YHL039W Hypothetical ORF
uniprot|Q9HF97 Zygosaccharomyces rouxii cof1 Cofilin
weakly similar to uniprot|Q07887 Saccharomyces cerevisiae YLL049W
weakly similar to uniprot|P03874 Saccharomyces cerevisiae YHL038C CBP2 Protein required for splicing of COB aI5 intron Cytochrome B pre-mRNA processing protein
similar to uniprot|P38734 Saccharomyces cerevisiae YHL036W MUP3 Low affinity methionine permease, similar to Mup1p
similar to uniprot|P32386 Saccharomyces cerevisiae YLL048C
similar to uniprot|P10080 Saccharomyces cerevisiae YHL034C SBP1 Single-strand nucleic acid binding protein
highly similar to uniprot|P29453 Saccharomyces cerevisiae RPL8B and to YHL033C uniprot|P17076 Saccharomyces cerevisiae RPL8A Ribosomal protein L4 of the large (60S) ribosomal subunit
similar to uniprot|P32190 Saccharomyces cerevisiae YHL032C GUT1 Glycerol kinase converts glycerol to glycerol-3-phosphate glucose repression of expression is mediated by Adr1p and Ino2p-Ino4p derepression of expression on non-fermentable carbon sources is mediated by Opi1p and Rsf1p
uniprot|Q6RW11 Zygosaccharomyces rouxii FPS1 Glycerol facilitator
highly similar to uniprot|P38736 Saccharomyces cerevisiae YHL031C GOS1 v-SNARE protein involved in Golgi transport homolog of the mammalian protein GOS-28/GS28
similar to uniprot|Q07879 Saccharomyces cerevisiae YLL042C ATG10 Enzyme that mediates formation of the Atg12p-Atg5p conjugate which is a critical step in autophagy
highly similar to uniprot|P21801 Saccharomyces cerevisiae YLL041C SDH2 Iron-sulfur protein subunit of succinate dehydrogenase (Sdh1p Sdh2p Sdh3p Sdh4p) which couples the oxidation of succinate to the transfer of electrons to ubiquinone
similar to uniprot|Q07878 Saccharomyces cerevisiae YLL040C VPS13 homologous to human COH1 component of peripheral vacuolar membrane protein complex
similar to uniprot|P38737 Saccharomyces cerevisiae YHL030W ECM29 Major component of the proteasome tethers the proteasome core particle to the regulatory particle and enhances the stability of the proteasome
highly similar to uniprot|P04838 Saccharomyces cerevisiae YLL039c UBI4 ubiquitin
similar to uniprot|Q07872 Saccharomyces cerevisiae YLL038C ENT4 Protein of unknown function contains an N-terminal epsin-like domain
similar to uniprot|P32523 Saccharomyces cerevisiae YLL036C PRP19 Splicing factor associated with the spliceosome contains a U-box a motif found in a class of ubiquitin ligases
similar to uniprot|P38738 Saccharomyces cerevisiae YHL029C Cytoplasmic protein required for replication of Brome mosaic virus in S. cerevisiae which is a model system for studying replication of positive-strand RNA viruses in their natural hosts
weakly similar to uniprot|P33400 Saccharomyces cerevisiae YHL027W
similar to uniprot|Q9P4W6 Saccharomyces cerevisiae YLL035W GRC3 Protein of unknown function required for cell growth and possibly involved in rRNA processing mRNA is cell cycle regulated
highly similar to uniprot|Q07844 Saccharomyces cerevisiae YLL034C RIX7 Putative ATPase of the AAA family required for export of pre-ribosomal large subunits from the nucleus distributed between the nucleolus nucleoplasm and nuclear periphery depending on growth conditions
similar to uniprot|P38740 Saccharomyces cerevisiae YHL026C Hypothetical ORF
weakly similar to uniprot|P53148 Saccharomyces cerevisiae YGL093W SPC105 Protein required for accurate chromosome segregation localizes to the nuclear side of the spindle pole body forms a complex with Ydr532cp
similar to uniprot|P49687 Saccharomyces cerevisiae YGL092W NUP145 Essential nucleoporin catalyzes its own cleavage in vivo to generate a C-terminal fragment that assembles into the Nup84p subcomplex of the nuclear pore complex
highly similar to uniprot|P52920 Saccharomyces cerevisiae YGL091C NBP35 Essential nuclear protein evolutionarily conserved putative ATPase exhibits genetic interaction with CDC2 encoding the catalytic subunit of DNA polymerase delta
some similarities with uniprot|P53150 Saccharomyces cerevisiae YGL090W LIF1 Protein involved in DNA double-strand break repair physically interacts with DNA ligase 4 (Lig4p) homologous to mammalian XRCC4 protein
similar to uniprot|Q08925 Saccharomyces cerevisiae YPL184C Hypothetical ORF
some similarities with uniprot|Q08926 Saccharomyces cerevisiae YPL186C UIP4 Protein of unknown function
similar to uniprot|P01149 Saccharomyces cerevisiae YPL187W MF(ALPHA)1 Mating pheromone alpha-factor made by alpha cells interacts with mating type a cells to induce cell cycle arrest and other responses leading to mating also encoded by MF(ALPHA)2 although MF(ALPHA)1 produces most alpha-factor
highly similar to uniprot|Q06892 Saccharomyces cerevisiae YPL188W POS5 Mitochondrial NADH kinase phosphorylates NADH also phosphorylates NAD() with lower specificity required for the response to oxidative stress
similar to uniprot|P28263 Saccharomyces cerevisiae YEL012W UBC8 Ubiquitin-conjugating enzyme that negatively regulates gluconeogenesis by mediating the glucose-induced ubiquitination of fructose-1 6-bisphosphatase (FBPase) cytoplasmic enzyme that catalyzes the ubiquitination of histones in vitro
similar to uniprot|P40957 Saccharomyces cerevisiae YGL086W MAD1 Coiled-coil protein involved in the spindle-assembly checkpoint phosphorylated by Mps1p upon checkpoint activation which leads to inhibition of the activity of the anaphase promoting complex forms a complex with Mad2p
similar to uniprot|P53153 Saccharomyces cerevisiae YGL085W Hypothetical ORF
similar to uniprot|P53154 Saccharomyces cerevisiae YGL084C GUP1 Multimembrane-spanning protein and similar to uniprot|Q08929 Saccharomyces cerevisiae YPL189W GUP2
similar to uniprot|P53009 Saccharomyces cerevisiae YGL083W SCY1 Suppressor of GTPase mutant
similar to uniprot|Q3E823 Saccharomyces cerevisiae YPL189C-A
similar to uniprot|P38996 Saccharomyces cerevisiae YPL190C NAB3 Single stranded DNA binding protein acidic ribonucleoprotein required for termination of non-poly(A) transcripts and efficient splicing interacts with Nrd1p
similar to uniprot|P53155 Saccharomyces cerevisiae YGL082W and similar to uniprot|Q08930 Saccharomyces cerevisiae YPL191C Hypothetical ORFs
some similarities with uniprot|P53156 Saccharomyces cerevisiae YGL081W Hypothetical ORF
some similarities with uniprot|Q08931 Saccharomyces cerevisiae YPL192C
similar to uniprot|Q08932 Saccharomyces cerevisiae YPL193W RSA1 RiboSome Assembly
similar to uniprot|P53157 Saccharomyces cerevisiae YGL080W FMP37
similar to uniprot|Q08949 Saccharomyces cerevisiae YPL194W DDC1 DNA damage checkpoint protein part of a PCNA-like complex required for DNA damage response required for pachytene checkpoint to inhibit cell cycle in response to unrepaired recombination intermediates potential Cdc28p substrate
similar to uniprot|Q7LIB1 Saccharomyces cerevisiae YPL195W APL5 Delta-like subunit of the yeast AP-3 complex which functions in transport of alkaline phosphatase to the vacuole via the alternate pathway suppressor of loss of casein kinase 1 function delta-like subunit of the yeast AP-3 adaptin component of the membrane-associated clathrin assembly complex
similar to uniprot|P53158 Saccharomyces cerevisiae YGL079W Hypothetical ORF
similar to uniprot|Q08952 Saccharomyces cerevisiae YPL196W OXR1 Protein of unknown function required for normal levels of resistance to oxidative damage null mutants are sensitive to hydrogen peroxide
similar to uniprot|P20447 Saccharomyces cerevisiae YGL078C DBP3 Putative ATP-dependent RNA helicase of the DEAD-box family involved in ribosomal biogenesis
similar to uniprot|P19807 Saccharomyces cerevisiae YGL077C HNM1 Choline transporter (permease) that also controls the uptake of nitrogen mustard expression is co-regulated with phospholipid biosynthetic genes and negatively regulated by choline and myo-inositol
highly similar to uniprot|P05737 Saccharomyces cerevisiae YGL076C RPL7A and to uniprot|Q12213 Saccharomyces cerevisiae YPL198W RPL7B Proteins component of the large (60S) ribosomal subunit
similar to uniprot|Q08954 Saccharomyces cerevisiae YPL199C Hypothetical ORF
weakly similar to uniprot|P53159 Saccharomyces cerevisiae YGL075C MPS2 Essential membrane protein localized at the nuclear envelope and spindle pole body (SPB) required for insertion of the newly duplicated SPB into the nuclear envelope potentially phosphorylated by Cdc28p
similar to uniprot|P10961 Saccharomyces cerevisiae YGL073W HSF1 Trimeric heat shock transcription factor activates multiple genes in response to hyperthermia recognizes variable heat shock elements
similar to uniprot|P22149 Saccharomyces cerevisiae YGL071W RCS1 Transcription factor involved in iron utilization and homeostasis binds the consensus site PyPuCACCCPu and activates the expression of target genes in response to changes in iron availability
highly similar to uniprot|P27999 Saccharomyces cerevisiae YGL070C RPB9 RNA polymerase II subunit B12.6 contacts DNA mutations affect transcription start site
putative mitochondrial 54S ribosomal protein MNP1
similar to uniprot|P53163 Saccharomyces cerevisiae YGL068W MNP1 Protein associated with the mitochondrial nucleoid
highly similar to uniprot|P06245 Saccharomyces cerevisiae YPL203W TPK2 Involved in nutrient control of cell growth and division cAMP-dependent protein kinase catalytic subunit
similar to uniprot|P29295 Saccharomyces cerevisiae YPL204W HRR25 Protein kinase involved in regulating diverse events including vesicular trafficking gene expression DNA repair and chromosome segregation binds the CTD of RNA pol II homolog of mammalian casein kinase 1delta (CK1delta)
highly similar to gnl|GLV|CAGL0J04400g Candida glabrata CAGL0J04400g and similar to YBL021C uniprot|P13434 Saccharomyces cerevisiae YBL021C HAP3 Subunit of the heme-activated glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex a transcriptional activator and global regulator of respiratory gene expression contains sequences contributing to both complex assembly and DNA binding
similar to uniprot|P36775 Saccharomyces cerevisiae YBL022C PIM1 Mitochondrial ATP-dependent protease involved in intramitochondrial proteolysis involved in degradation of misfolded proteins in mitochondria required for bigenesis and maintenance of mitochondria
similar to uniprot|P38067 Saccharomyces cerevisiae YBR006W UGA2 Succinate semialdehyde dehydrogenase involved in the utilization of gamma-aminobutyrate (GABA) as a nitrogen source part of the 4-aminobutyrate and glutamate degradation pathways localized to the cytoplasm
highly similar to uniprot|P29469 Saccharomyces cerevisiae YBL023C MCM2 Protein involved in DNA replication component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex
similar to uniprot|P38205 Saccharomyces cerevisiae YBL024W
highly similar to gnl|GLV|CAGL0K01969g Candida glabrata CAGL0K01969g and similar to YBL025W uniprot|P38204 Saccharomyces cerevisiae YBL025W RRN10 subunit of UAF (upstream activation factor) involved in promoting high level transcription of rDNA Upstream activation factor subunit
similar to uniprot|P40083 Saccharomyces cerevisiae YER137C Hypothetical ORF
highly similar to uniprot|P38203 Saccharomyces cerevisiae YBL026W LSM2 Component of small nuclear ribonucleoprotein complexes involved in RNA processing splicing and decay
highly similar to uniprot|P39958 Saccharomyces cerevisiae YER136W GDI1 GDP dissociation inhibitor regulates vesicle traffic in secretory pathways by regulating the dissociation of GDP from the Sec4/Ypt/rab family of GTP binding proteins
similar to uniprot|Q12298 Saccharomyces cerevisiae YDR061W Mitochondrial protein member of the ATP-binding cassette (ABC) transporter family transcriptionally activated by Yrm1p along with genes involved in multidrug resistance
highly similar to uniprot|P40970 Saccharomyces cerevisiae YDR062W LCB2 Component of serine palmitoyltransferase responsible along with Lcb1p for the first committed step in sphingolipid synthesis which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine
similar to uniprot|Q12156 Saccharomyces cerevisiae YDR063W Hypothetical ORF
highly similar to uniprot|P05756 Saccharomyces cerevisiae YDR064W RPS13 Protein component of the small (40S) ribosomal subunit; has similarity to E. coli S15 and rat S13 ribosomal proteins
similar to uniprot|P31755 Saccharomyces cerevisiae YGL038C OCH1 Mannosyltransferase of the cis-Golgi apparatus initiates the polymannose outer chain elongation of N-linked oligosaccharides of glycoproteins
similar to uniprot|P53184 Saccharomyces cerevisiae YGL037C PNC1 NAD() salvage pathway gene pyrazinamidase and nicotinamidase
similar to uniprot|P53185 Saccharomyces cerevisiae YGL036W Mtf1 Two Hybrid Clone 2
similar to uniprot|P48234 Saccharomyces cerevisiae YGR145W ENP2 Essential nucleolar protein of unknown function contains WD repeats interacts with Mpp10p and Bfr2p and has homology to Spb1p
similar to uniprot|Q752V4 Ashbya gossypii AFR469W SEC9 Protein transport protein SEC9 and weakly similar to YGR009C uniprot|P40357 Saccharomyces cerevisiae YGR009C SEC9 t- SNARE protein important for fusion of secretory vesicles with the plasma membrane
weakly similar to uniprot|P48235 Saccharomyces cerevisiae YGR146C
some similarities with uniprot|P27705 Saccharomyces cerevisiae YGL035C
similar to uniprot|P53187 Saccharomyces cerevisiae YGL033W HOP2 Meiosis-specific protein that localizes to chromosomes preventing synapsis between nonhomologous chromosomes and ensuring synapsis between homologs complexes with Mnd1p to promote homolog pairing and meiotic double-strand break repair
similar to gnl|GLV|KLLA0E10879g Kluyveromyces lactis KLLA0E10879g and some similarites with YGR147C uniprot|P37293 Saccharomyces cerevisiae YGR147C NAT2 N alpha- acetyl-transferase transfers acetyl group from acetyl coenzyme A to the N-terminal methionine residues of proteins
similar to uniprot|P04449 Saccharomyces cerevisiae YGL031C RPL24A and to uniprot|P24000 Saccharomyces cerevisiae YGR148C RPL24B
highly similar to uniprot|P14120 Saccharomyces cerevisiae YGL030W RPL30 Protein component of the large (60S) ribosomal subunit
similar to uniprot|P48236 Saccharomyces cerevisiae YGR149W Hypothetical ORF
similar to uniprot|P48237 Saccharomyces cerevisiae YGR150C Hypothetical ORF
similar to uniprot|P53188 Saccharomyces cerevisiae YGL029W CGR1 Coiled-coil protein that may contribute to compartmentalization of nucleolar constituents expression is growth-regulated
similar to uniprot|Q5AKC7 Candida albicans SCW11 Potential cell wall glucanase and some similarites with YGL028C uniprot|P53189 Saccharomyces cerevisiae
similar to uniprot|P53008 Saccharomyces cerevisiae YGL027C CWH41 Processing alpha glucosidase I involved in assembly of cell wall beta 1 6 glucan and asparagine-linked protein glycosylation ER type II integral membrane N-glycoprotein disruption leads to a K1 killer toxin-resistant phenotype
similar to uniprot|P32786 Saccharomyces cerevisiae YBL014C RRN6 involved in the transcription of 35S rRNA genes by RNA polymerase I member of yeast Pol I core factor (CF) also composed of Rrn11p Rrn7p and TATA-binding protein
highly similar to uniprot|P00931 Saccharomyces cerevisiae YGL026C TRP5 tryptophan synthetase
some similarities with uniprot|P40356 Saccharomyces cerevisiae YGL025C PGD1 Subunit of the Mediator global transcriptional cofactor complex which is part of the RNA polymerase II holoenzyme and plays an essential role in basal and activated transcription direct target of the Cyc8p-Tup1p transcriptional corepressor
similar to uniprot|P32785 Saccharomyces cerevisiae YBL013W FMT1 Methionyl-tRNA formyltransferase catalyzes the formylation of initiator Met-tRNA in mitochondria potential Cdc28p substrate
similar to uniprot|P32784 Saccharomyces cerevisiae YBL011W SCT1 High copy suppressor of choline-transport mutants
weakly similar to uniprot|P53191 Saccharomyces cerevisiae YGL023C
highly similar to uniprot|P39007 Saccharomyces cerevisiae YGL022W STT3 Subunit of the oligosaccharyltransferase complex of the ER lumen which catalyzes asparagine-linked glycosylation of newly synthesized proteins forms a subcomplex with Ost3p and Ost4p and is directly involved in catalysis
similar to uniprot|P32788 Saccharomyces cerevisiae YBL010C Hypothetical ORF
some similarities with uniprot|P32789 Saccharomyces cerevisiae YBL009W haspin
similar to uniprot|P53192 Saccharomyces cerevisiae YGL020C MDM39 Protein involved in determination of mitochondrial structure
highly similar to uniprot|P43639 Saccharomyces cerevisiae YGL019W CKB1 beta (38kDa) subunit of protein kinase CK2
similar to uniprot|P53193 Saccharomyces cerevisiae YGL018C JAC1 Molecular chaperone involved with partner Ssq1p in assembly of Fe/S clusters and in mitochondrial iron metabolism contains a J domain typical to J-type chaperones localizes to the mitochondrial matrix
similar to uniprot|P16639 Saccharomyces cerevisiae YGL017W ATE1 Arginyl-tRNA-protein transferase catalyzes post-translational conjugation of arginine to the amino termini of acceptor proteins which are then subject to degradation via the N-end rule pathway
similar to uniprot|P32767 Saccharomyces cerevisiae YGL016W KAP122 Karyopherin beta responsible for import of the Toa1p-Toa2p complex into the nucleus binds to nucleoporins Nup1p and Nup2p may play a role in regulation of pleiotropic drug resistance
similar to uniprot|P32479 Saccharomyces cerevisiae YBL008W HIR1 Non-essential transcriptional corepressor involved in the cell cycle-regulated transcription of histone H2A H2B H3 and H4 genes contributes to nucleosome formation heterochromatic gene silencing and formation of functional kinetochores
highly similar to uniprot|P07264 Saccharomyces cerevisiae YGL009C LEU1 Isopropylmalate isomerase catalyzes the second step in the leucine biosynthesis pathway
similar to uniprot|P32790 Saccharomyces cerevisiae YBL007C SLA1 Cytoskeletal protein binding protein required for assembly of the cortical actin cytoskeleton contains 3 SH3 domains interacts with proteins regulating actin dynamics and with proteins required for endocytosis
similar to uniprot|P25338 Saccharomyces cerevisiae YGL010W Hypothetical ORF
highly similar to uniprot|P21243 Saccharomyces cerevisiae YGL011C SCL1 Proteasome subunit YC7alpha/Y8 (protease yscE subunit 7)
similar to gnl|GLV|CAGL0E02761g Candida glabrata CAGL0E02761g and some similarites with YBL006C uniprot|P38210 Saccharomyces cerevisiae YBL006C LDB7 Protein of unknown function null mutant shows a reduced affinity for the alcian blue dye suggesting a decreased net negative charge of the cell surface
highly similar to gnl|GLV|CAGL0A00429g Candida glabrata CAGL0A00429g and similar to YGL012W uniprot|P25340 Saccharomyces cerevisiae YGL012W ERG4 C- 24(28) sterol reductase catalyzes the final step in ergosterol biosynthesis mutants are viable but lack ergosterol
similar to uniprot|P12383 Saccharomyces cerevisiae YGL013C PDR1 Zinc cluster protein that is a master regulator involved in recruiting other zinc cluster proteins to pleiotropic drug response elements (PDREs) to fine tune the regulation of multidrug resistance genes
similar to uniprot|P25339 Saccharomyces cerevisiae YGL014W PUF4 member of the PUF protein family YGL014W
uniprot|P24545 Zygosaccharomyces rouxii Plasma membrane ATPase
similar to uniprot|Q04894 Saccharomyces cerevisiae YMR318C ADH6 NADPH-dependent cinnamyl alcohol dehydrogenase family member with broad substrate specificity may be involved in fusel alcohol synthesis or in aldehyde tolerance
similar to uniprot|P39707 Saccharomyces cerevisiae YAR008W
similar to uniprot|P38929 Saccharomyces cerevisiae YGL006W PMC1 May be involved in depleting cytosol of Ca2 ions putative vacuolar Ca2 ATPase
similar to uniprot|P53195 Saccharomyces cerevisiae YGL005C COG7 Component of the conserved oligomeric Golgi complex
similar to uniprot|P53196 Saccharomyces cerevisiae YGL004C RPN14 Putative non-ATPase subunit of the 19S regulatory particle of the 26S proteasome localized to the cytoplasm
highly similar to uniprot|P22336 Saccharomyces cerevisiae YAR007C RFA1 Subunit of heterotrimeric Replication Factor A (RF-A) which is a highly conserved single-stranded DNA binding protein involved in DNA replication repair and recombination
similar to uniprot|P53197 Saccharomyces cerevisiae YGL003C CDH1 CDC20 homolog 1 protein required for Clb2 and Ase1 degradation
similar to uniprot|P39706 Saccharomyces cerevisiae YAR003W SWD1 Subunit of the COMPASS complex which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres
similar to uniprot|Q05359 Saccharomyces cerevisiae YAR002C-A ERP1 Protein that forms a heterotrimeric complex with Erp2p Emp24p and Erv25p member along with Emp24p and Erv25p of the p24 family involved in ER to Golgi transport and localized to COPII-coated vesicles
weakly similar to uniprot|P39705 Saccharomyces cerevisiae YAR002W NUP60 Subunit of the nuclear pore complex (NPC) functions to anchor Nup2p to the NPC in a dynamic process that is controlled by the nucleoplasmic concentration of Gsp1p-GTP potential Cdc28p substrate
uniprot|Q96WU2 Zygosaccharomyces rouxii gl001 Putative C- 3 sterol dehydrogenase
uniprot|Q96WU1 Zygosaccharomyces rouxii orf Hypothetical protein, highly similar to YGR001C uniprot|P53200 Saccharomyces cerevisiae YGR001C Protein with similarity to methyltransferase family members; required for replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts
similar to uniprot|P34111 Saccharomyces cerevisiae YAL001C TFC3 Largest of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauB domain of TFIIIC that binds DNA at the BoxB promoter sites of tRNA and similar genes; cooperates with Tfc6p in DNA binding
similar to uniprot|P39702 Saccharomyces cerevisiae YAL002W VPS8 involved in vacuolar protein sorting required for localization and trafficking of the CPY sorting receptor Vps8p is a membrane-associated hydrophilic protein which contains a C-terminal cysteine-rich region that conforms to the H2 variant of the RING finger Zn2 binding motif.
highly similar to uniprot|P32471 Saccharomyces cerevisiae YAL003W EFB1 Translation elongation factor 1 beta
similar to uniprot|Q06168 Saccharomyces cerevisiae YLR321C SFH1 Involved in chromatin modeling cell cycle progression homolog of Snf5p member of the chromatin remodeling complex RSC
weakly similar to uniprot|Q06162 Saccharomyces cerevisiae YLR315W NKP2
similar to uniprot|Q9URQ3 Saccharomyces cerevisiae YLR316C TAD3 tRNA-specific adenosine-34 deaminase subunit Tad3p
similar to uniprot|Q06163 Saccharomyces cerevisiae YLR318W EST2 Reverse transcriptase subunit of the telomerase holoenzyme essential for telomerase core catalytic activity involved in other aspects of telomerase assembly and function
similar to uniprot|P41697 Saccharomyces cerevisiae YLR319C BUD6 Actin- and formin-interacting protein involved in actin cable nucleation and polarized cell growth isolated as bipolar budding mutant potential Cdc28p substrate
weakly similar to uniprot|Q06164 Saccharomyces cerevisiae YLR320W MMS22 Protein involved in resistance to ionizing radiation acts with Mms1p in a repair pathway that may be involved in resolving replication intermediates or preventing the damage caused by blocked replication forks
similar to uniprot|P53201 Saccharomyces cerevisiae YGR002C SWC4 Protein of unknown function component of the Swr1p complex that incorporates Htz1p into chromatin component of the NuA4 histone acetyltransferase complex
similar to uniprot|P53202 Saccharomyces cerevisiae YGR003W
similar to uniprot|P53769 Saccharomyces cerevisiae YLR323C
similar to uniprot|Q06169 Saccharomyces cerevisiae YLR324W PEX30 Peroxisomal integral membrane protein involved in negative regulation of peroxisome number partially functionally redundant with Pex31p genetic interactions suggest action at a step downstream of steps mediated by Pex28p and Pex29p
highly similar to uniprot|P49167 Saccharomyces cerevisiae YLR325C RPL38 Protein component of the large (60S) ribosomal subunit
similar to uniprot|P41896 Saccharomyces cerevisiae YGR005C TFG2 transcription initiation factor TFIIF middle subunit
similar to uniprot|P33411 Saccharomyces cerevisiae YGR006W PRP18 Splicing factor involved in the positioning of the 3' splice site during the second catalytic step of splicing recruited to the spliceosome by Slu7p
similar to uniprot|Q06170 Saccharomyces cerevisiae YLR326W Hypothetical ORF
similar to uniprot|P33412 YGR007W Saccharomyces cerevisiae MUQ1 Choline phosphate cytidylyltransferase
similar to uniprot|Q06177 Saccharomyces cerevisiae YLR327C RBF9 Hypothetical ORF
highly similar to uniprot|Q06178 Saccharomyces cerevisiae YLR328W NMA1 Nicotinic acid mononucleotide adenylyltransferase involved in NAD() salvage pathway
some similarities with uniprot|Q07927 Saccharomyces cerevisiae YLR012C Hypothetical ORF
highly similar to uniprot|P53206 Saccharomyces cerevisiae YGR012W Hypothetical ORF
similar to uniprot|P53207 Saccharomyces cerevisiae YGR013W SNU71 associated with U1 snRNP (no counterpart in mammalian U1 snRNP contains few SR- RE- and RD-dipeptides U1 snRNP protein
weakly similar to uniprot|P32334 Saccharomyces cerevisiae YGR014W MSB2 Mucin family member at the head of the Cdc42p- and MAP kinase-dependent filamentous growth signaling pathway also functions as an osmosensor in parallel to the Sho1p-mediated pathway potential Cdc28p substrate
similar to uniprot|P53208 Saccharomyces cerevisiae YGR015C Hypothetical ORF
similar to uniprot|P53209 Saccharomyces cerevisiae YGR016W Hypothetical ORF
similar to uniprot|Q02721 Saccharomyces cerevisiae YLR329W REC102 Protein involved in early stages of meiotic recombination required for chromosome synapsis forms a complex with Rec104p and Spo11p necessary during the initiation of recombination
highly similar to uniprot|P53295 Saccharomyces cerevisiae YGR173W
similar to uniprot|P42940 YGR207C Saccharomyces cerevisiae YGR2 Hypothetical ORF
similar to uniprot|P42939 Saccharomyces cerevisiae YGR206W Hypothetical ORF
highly similar to uniprot|P47096 Saccharomyces cerevisiae YJR025C BNA1 3-hydroxyanthranilic acid dioxygenase required for biosynthesis of nicotinic acid from tryptophan via kynurenine pathway
similar to uniprot|P47095 Saccharomyces cerevisiae YJR024C Hypothetical ORF
similar to uniprot|P47093 Saccharomyces cerevisiae YJR022W LSM8 Component of small nuclear ribonucleoprotein complexes involved in RNA processing and splicing
similar to uniprot|P42938 Saccharomyces cerevisiae YGR205W Protein that binds ATP crystal structure resembles that of E.coli pantothenate kinase
similar to uniprot|P41903 Saccharomyces cerevisiae YJR019C TES1 Thioesterase peroxisomal acyl-CoA thioesterase
highly similar to uniprot|P07245 Saccharomyces cerevisiae YGR204W ADE3 Cytoplasmic trifunctional enzyme C1-tetrahydrofolate synthase involved in single carbon metabolism and required for biosynthesis of purines thymidylate methionine and histidine
highly similar to gnl|GLV|KLLA0E16610g Kluyveromyces lactis KLLA0E16610g and similar to YJR017C uniprot|P22696 Saccharomyces cerevisiae ESS1 Peptidylprolyl-cis/trans-isomerase (PPIase) specific for phosphorylated serine and threonine residues N-terminal to proline
similar to uniprot|P42937 YGR203W Saccharomyces cerevisiae Probable protein tyrosine phosphatase of the CDC25-like phosphatase family
highly similar to uniprot|P39522 Saccharomyces cerevisiae YJR016C ILV3 Dihydroxyacid dehydratase catalyzes third step in the common pathway leading to biosynthesis of branched-chain amino acids
similar to uniprot|P42935 Saccharomyces cerevisiae YGR200C ELP2 Elongator protein part of the six-subunit RNA polymerase II Elongator histone acetyltransferase complex target of Kluyveromyces lactis zymocin
similar to uniprot|P42934 Saccharomyces cerevisiae YGR199W PMT6 Transfers mannose residues from dolichyl phosphate-D-mannose to specific serine/threonine residues of proteins in the secretory pathway dolichyl phosphate-D-mannose:protein O-D-mannosyltransferase
some similarities with uniprot|P42835 Saccharomyces cerevisiae YNL327W EGT2 Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase required for proper cell separation after cytokinesis expression is activated by Swi5p and tightly regulated in a cell cycle-dependent manner
highly similar to uniprot|P32318 Saccharomyces cerevisiae YGR144W THI4 Protein required for thiamine biosynthesis and for mitochondrial genome stability
similar to uniprot|P46951 Saccharomyces cerevisiae YGR198W Essential protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
similar to uniprot|P47089 Saccharomyces cerevisiae YJR014W RBF22 Hypothetical ORF
some similarities with uniprot|P46949 Saccharomyces cerevisiae YGR196C FYV8 Protein of unknown function required for survival upon exposure to K1 killer toxin
highly similar to uniprot|P46948 Saccharomyces cerevisiae YGR195W SKI6 superkiller ExtraCellular Mutant Ribosomal RNA Processing homolog of RNAse PH
similar to uniprot|P47088 Saccharomyces cerevisiae YJR013W GPI14 Glycosylphosphatidylinositol-alpha 1 4 mannosyltransferase I involved in GPI anchor biosynthesis requires Pbn1p for function homolog of mammalian PIG-M
some similarities with uniprot|P47087 Saccharomyces cerevisiae YJR012C Protein required for cell viability
similar to uniprot|P47086 Saccharomyces cerevisiae YJR011C Hypothetical ORF
similar to uniprot|P46965 Saccharomyces cerevisiae YJR010C-A SPC1 Subunit of the signal peptidase complex (SPC) which cleaves the signal sequence from proteins targeted to the endoplasmic reticulum (ER) homolog of the SPC12 subunit of mammalian signal peptidase complex
similar to uniprot|P42826 Saccharomyces cerevisiae YGR194C; XKS1 third enzyme in the xylose pathway, Xylulokinase
similar to uniprot|P16451 Saccharomyces cerevisiae YGR193C PDX1 Dihydrolipoamide dehydrogenase (E3)-binding protein (E3BP) of the mitochondrial pyruvate dehydrogenase (PDH) complex plays a structural role in the complex by binding and positioning E3 to the dihydrolipoamide acetyltransferase (E2) core
highly similar to uniprot|P08536 Saccharomyces cerevisiae YJR010W MET3 ATP sulfurylase catalyzes the primary step of intracellular sulfate activation essential for assimilatory reduction of sulfate to sulfide involved in methionine metabolism
uniprot|P08439 Zygosaccharomyces rouxii Glyceraldehyde-3- phosphate dehydrogenase
similar to uniprot|P47085 Saccharomyces cerevisiae YJR008W Hypothetical ORF
highly similar to uniprot|P20459 Saccharomyces cerevisiae YJR007W SUI2 Alpha subunit of the translation initiation factor eIF2 involved in the identification of the start codon phosphorylation of Ser51 is required for regulation of translation by inhibiting the exchange of GDP for GTP
highly similar to uniprot|P53301 Saccharomyces cerevisiae YGR189C CRH1 Putative glycosidase of the cell wall may have a role in cell wall architecture
similar to uniprot|P47076 Saccharomyces cerevisiae YJL011C RPC17 RNA polymerase III subunit C17 physically interacts with C31 C11 and TFIIIB70 may be involved in the recruitment of pol III by the preinitiation complex
highly similar to uniprot|P47075 Saccharomyces cerevisiae YJL012C VTC4 Phosphate metabolism transcription is regulated by PHO system polyphosphate synthetase (putative)
similar to uniprot|P41695 Saccharomyces cerevisiae YGR188C BUB1 Protein kinase that forms a complex with Mad1p and Bub3p that is crucial in the checkpoint mechanism required to prevent cell cycle progression into anaphase in the presence of spindle damage associates with centromere DNA via Skp1p
highly similar to uniprot|P39077 Saccharomyces cerevisiae YJL014W CCT3 Subunit of the cytosolic chaperonin Cct ring complex related to Tcp1p required for the assembly of actin and tubulins in vivo
weakly similar to uniprot|P47072 Saccharomyces cerevisiae YJL016W
weakly similar to uniprot|P47069 Saccharomyces cerevisiae YJL019W MPS3 Essential integral membrane protein required for spindle pole body duplication and for nuclear fusion localizes to the spindle pole body half bridge interacts with DnaJ-like chaperone Jem1p and with centrin homolog Cdc31p
mitochondrial 37S ribosomal protein MRPS35
highly similar to uniprot|P53292 Saccharomyces cerevisiae YGR165W MRPS35 Mitochondrial ribosomal protein of the small subunit
similar to uniprot|P41815 Saccharomyces cerevisiae YDR046C BAP3 Amino acid permease involved in the uptake of cysteine leucine isoleucine and valine
similar to uniprot|Q7LHX4 Saccharomyces cerevisiae YDR051C Hypothetical ORF
highly similar to uniprot|P00942 Saccharomyces cerevisiae YDR050C TPI1 induced under stress conditions triosephosphate isomerase
similar to uniprot|P38242 Saccharomyces cerevisiae YBR070C ALG14 Essential protein required for the second step of dolichyl-linked oligosaccharide synthesis; involved in N-linked glycosylation; similar to bacterial glycosyltransferases
similar to uniprot|P38086 Saccharomyces cerevisiae YBR073W RDH54 DNA-dependent ATPase stimulates strand exchange by modifying the topology of double-stranded DNA involved in the recombinational repair of double-strand breaks in DNA during mitosis and meiosis proposed to be involved in crossover interference
similar to uniprot|Q66RH0 Saccharomyces cerevisiae YDR049W Hypothetical ORF
highly similar to uniprot|P32347 Saccharomyces cerevisiae YDR047W HEM12 Uroporphyrinogen decarboxylase catalyzes the fifth step in the heme biosynthetic pathway localizes to both the cytoplasm and nucleus activity inhibited by Cu2 Zn2 Fe2 Fe3 and sulfhydryl-specific reagents
similar to uniprot|P38244 Saccharomyces cerevisiae YBR074W Hypothetical ORF
similar to uniprot|P32325 Saccharomyces cerevisiae YDR052C DBF4 Regulatory subunit of Cdc7p-Dbf4p kinase complex required for Cdc7p kinase activity and initiation of DNA replication phosphorylates the Mcm2-7 family of proteins cell cycle regulated
similar to uniprot|P38247 Saccharomyces cerevisiae YBR077C SLM4 Protein with a potential role in actin cytoskeleton organization possible component of the TOR nutrient signaling pathway gene exhibits synthetic genetic interaction with MSS4 encoding phosphatidylinositol 4-phosphate kinase
highly similar to uniprot|Q750Z0 Ashbya gossypii AGL203C AGL203Cp and similar to YDR054C uniprot|P14682 Saccharomyces cerevisiae YDR054C CDC34 Ubiquitin-conjugating enzyme or E2 together with Skp1p Rbx1p Cdc53p and an F-box protein forms a ubiquitin-protein ligase called the SCF complex which regulates cell cycle progression by targeting key substrates for degradation
similar to uniprot|P22580 Saccharomyces cerevisiae YDR242W AMD2
similar to uniprot|Q12355 Saccharomyces cerevisiae YDR055W PST1 Cell wall protein and similar to uniprot|P38248 Saccharomyces cerevisiaeYBR078W ECM33
similar to uniprot|P38249 Saccharomyces cerevisiae YBR079C RPG1 Subunit of the core complex of translation initiation factor 3(eIF3) essential for translation part of a subcomplex (Prt1p-Rpg1p-Nip1p) that stimulates binding of mRNA and tRNA(i)Met to ribosomes
highly similar to uniprot|P18759 Saccharomyces cerevisiae YBR080C SEC18 ATPase required for the release of Sec17p during the 'priming' step in homotypic vacuole fusion and for ER to Golgi transport homolog of the mammalian NSF
similar to uniprot|Q12025 Saccharomyces cerevisiae YDR056C Hypothetical ORF
weakly similar to uniprot|Q04313 Saccharomyces cerevisiae YDR057W YOS9 Glycoprotein of the ER membrane involved in ER-to-Golgi transport of glycosylphosphatidylinositol (GPI)-anchored proteins
similar to uniprot|P35177 Saccharomyces cerevisiae YBR081C SPT7 Subunit of the SAGA transcriptional regulatory complex involved in proper assembly of the complex also present as a C-terminally truncated form in the SLIK/SALSA transcriptional regulatory complex
highly similar to uniprot|P15731 Saccharomyces cerevisiae YBR082C UBC4 Ubiquitin-conjugating enzyme that mediates degradation of short-lived and abnormal proteins interacts with E3-CaM in ubiquitinating calmodulin interacts with many SCF ubiquitin protein ligases component of the cellular stress response
similar to uniprot|Q12176 Saccharomyces cerevisiae YDR060W MAK21 Protein required for large (60S) ribosomal subunit biogenesis involved in nuclear export of pre-ribosomes required for maintenance of dsRNA virus homolog of human CAATT-binding protein
some similarities with uniprot|P18412 Saccharomyces cerevisiae YBR083W TEC1 transcription factor of the TEA/ATTS DNA-binding domain family regulator of Ty1 expression
highly similar to uniprot|P09440 Saccharomyces cerevisiae YBR084W MIS1 Mitochondrial C1-tetrahydrofolate synthase involved in interconversion between different oxidation states of tetrahydrofolate (THF) provides activities of formyl-THF synthetase methenyl-THF cyclohydrolase and methylene-THF dehydrogenase
highly similar to uniprot|P05735 Saccharomyces cerevisiae YBR084C-A RPL19A and to uniprot|P05735 Saccharomyces cerevisiae YBL027W RPL19B Proteins component of the large (60S) ribosomal subunit
similar to uniprot|P38202 Saccharomyces cerevisiae YBL028C Hypothetical ORF
some similarities with uniprot|P38201 Saccharomyces cerevisiae YBL029W Hypothetical ORF
similar to uniprot|Q3E756 Saccharomyces cerevisiae YBL029C-A Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cell periphery has potential orthologs in Saccharomyces species and in Yarrowia lipolytica
highly similar to uniprot|P18239 Saccharomyces cerevisiae YBL030C PET9 Major ADP/ATP carrier of the mitochondrial inner membrane exchanges cytosolic ADP for mitochondrially synthesized ATP Pet9p and Sal1p have an overlapping function critical for viability
weakly similar to uniprot|P38200 Saccharomyces cerevisiae YBL031W SHE1 Cytoskeletal protein of unknown function overexpression causes growth arrest
similar to uniprot|P38199 Saccharomyces cerevisiae YBL032W
similar to uniprot|P38066 Saccharomyces cerevisiae YBL033C RIB1 GTP cyclohydrolase II catalyzes the first step of the riboflavin biosynthesis pathway
highly similar to uniprot|O43137 Saccharomyces cerevisiae YBR085C-A Hypothetical ORF
similar to uniprot|P38198 Saccharomyces cerevisiae YBL034C STU1 Component of the mitotic spindle that binds to interpolar microtubules via its association with beta-tubulin (Tub2p) required for interpolar microtubules to provide an outward force on the spindle poles
similar to uniprot|P38121 Saccharomyces cerevisiae YBL035C POL12 Subunit of the DNA polymerase alpha-primase complex required for the initiation of DNA replication during mitotic DNA synthesis and premeiotic DNA synthesis
weakly similar to uniprot|P38250 Saccharomyces cerevisiae YBR086C IST2
weakly similar to uniprot|Q04814 Saccharomyces cerevisiae YMR252C Hypothetical ORF
similar to uniprot|Q04835 Saccharomyces cerevisiae YMR253C Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
similar to uniprot|Q05667 Saccharomyces cerevisiae YOL053W Hypothetical ORF
some similarities with uniprot|Q12161 Saccharomyces cerevisiae YOL054W PSH1 Nuclear protein putative RNA polymerase II elongation factor isolated as Pob3p/Spt16p-binding protein
similar to uniprot|P08468 Saccharomyces cerevisiae YMR257C PET111 Specific translational activator for the COX2 mRNA located in the mitochondrial inner membrane
similar to uniprot|Q04847 Saccharomyces cerevisiae YMR258C Hypothetical ORF
similar to uniprot|Q03496 Saccharomyces cerevisiae YMR259C Hypothetical ORF
highly similar to uniprot|P38912 Saccharomyces cerevisiae YMR260C TIF11 Translation initiation factor eIF1A
similar to uniprot|P38426 Saccharomyces cerevisiae YMR261C TPS3 115 kD regulatory subunit of trehalose-6-phosphate synthase/phosphatase complex
similar to uniprot|P38430 Saccharomyces cerevisiae YMR262W Hypothetical ORF
similar to uniprot|P38429 Saccharomyces cerevisiae YMR263W SAP30 Subunit of a histone deacetylase complex along with Rpd3p and Sin3p that is involved in silencing at telomeres rDNA and silent mating-type loci
similar to uniprot|P38428 Saccharomyces cerevisiae YMR264W CUE1 Endoplasmic reticulum membrane protein that recruits the ubiquitin-conjugating enzyme Ubc7p to the ER where it functions in protein degradation contains a CUE domain that binds ubiquitin to facilitate intramolecular monoubiquitination
similar to uniprot|Q04199 Saccharomyces cerevisiae YML102W CAC2 Component of the chromatin assembly complex (with Rlf2p and Msi1p) that assembles newly synthesized histones onto recently replicated DNA required for building functional kinetochores conserved from yeast to humans
similar to uniprot|Q03508 Saccharomyces cerevisiae YMR265C Hypothetical ORF
similar to uniprot|Q03516 Saccharomyces cerevisiae YMR266W RSN1 Overexpression rescues sro7/sop1 in NaCl. Encodes a membrane protein.
similar to uniprot|P28239 Saccharomyces cerevisiae YMR267W PPA2 Mitochondrial inorganic pyrophosphatase required for mitochondrial function and possibly involved in energy generation from inorganic pyrophosphate
similar to uniprot|P52593 Saccharomyces cerevisiae YML103C NUP188 Subunit of the nuclear pore complex (NPC)
similar to uniprot|P49960 Saccharomyces cerevisiae YMR268C PRP24 Splicing factor that reanneals U4 and U6 snRNPs during spliceosome recycling
weakly similar to uniprot|Q03525 Saccharomyces cerevisiae YMR269W
similar to uniprot|Q01846 Saccharomyces cerevisiae YML104C MDM1 Intermediate filament protein required for nuclear and mitochondrial transmission to daughter buds
similar to uniprot|P53437 Saccharomyces cerevisiae YMR270C RRN9 Upstream activation factor subunit
highly similar to uniprot|P29478 Saccharomyces cerevisiae YML105C SEC65 signal recognition particle subunit homologue of mammalian SRP19
highly similar to uniprot|P13298 Saccharomyces cerevisiae YML106W URA5 Fifth step in pyrimidine biosynthesis pathway Orotate phosphoribosyltransferase 1
weakly similar to uniprot|Q03760 Saccharomyces cerevisiae YML107C Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery
similar to uniprot|Q03529 Saccharomyces cerevisiae YMR272C SCS7 Required for the hydroxylation of the very long chain fatty acid (VLCFA) located in the endoplasmic reticulum desaturase/hydroxylase enzyme
highly similar to uniprot|Q03759 Saccharomyces cerevisiae YML108W defines a new subfamily of the split beta-alpha-beta sandwiches.
similar to uniprot|P54786 Saccharomyces cerevisiae YML109W ZDS2 Protein that interacts with silencing proteins at the telomere involved in transcriptional silencing paralog of Zds1p
similar to uniprot|Q03530 Saccharomyces cerevisiae YMR274C RCE1 Type II CAAX prenyl protease
highly similar to gnl|GLV|CAGL0J06710g Candida glabrata CAGL0J06710g and similar to YML110C uniprot|P49017 Saccharomyces cerevisiae YML110C COQ5 2- hexaprenyl-6-methoxy-1 4-benzoquinone methyltransferase involved in ubiquinone (Coenzyme Q) biosynthesis located in mitochondria
similar to uniprot|Q03758 Saccharomyces cerevisiae YML111W BUL2 Component of the Rsp5p E3-ubiquitin ligase complex involved in intracellular amino acid permease sorting functions in heat shock element mediated gene expression essential for growth in stress conditions functional homolog of BUL1
similar to uniprot|P46963 Saccharomyces cerevisiae YML112W CTK3 Gamma subunit of C-terminal domain kinase I (CTDK-I) which phosphorylates the C-terminal repeated domain of the RNA polymerase II large subunit (Rpo21p) to affect both transcription and pre-mRNA 3' end processing
some similarities with uniprot|P13483 Saccharomyces cerevisiae YML113W
similar to uniprot|P48510 Saccharomyces cerevisiae YMR276W DSK2 Nuclear-enriched ubiquitin-like polyubiquitin-binding protein required for spindle pole body (SPB) duplication and for transit through the G2/M phase of the cell cycle involved in proteolysis interacts with the proteasome
weakly similar to uniprot|Q03750 Saccharomyces cerevisiae YML114C TAF8 TFIID subunit (65 kDa) involved in RNA polymerase II transcription initiation
similar to uniprot|Q03254 Saccharomyces cerevisiae YMR277W FCP1 Carboxy-terminal domain (CTD) phosphatase
similar to uniprot|Q03262 Saccharomyces cerevisiae YMR278W Hypothetical ORF
similar to uniprot|Q12525 Saccharomyces cerevisiae YLL062C MHT1 S-methylmethionine-homocysteine methyltransferase
similar to uniprot|P23642 Saccharomyces cerevisiae YML115C VAN1 Mannosyltransferase with a role in protein N-glycosylation
similar to uniprot|Q03735 Saccharomyces cerevisiae YML117W NAB6 Putative RNA-binding protein based on computational analysis of large-scale protein-protein interaction data
similar to uniprot|Q75DZ4 Ashbya gossypii ABL121C ABL121Cp and similar to YMR280C uniprot|P39113 Saccharomyces cerevisiae YMR280C CAT8 Zinc cluster transcriptional activator
similar to uniprot|P23797 Saccharomyces cerevisiae YMR281W GPI12 ER membrane protein involved in the second step of glycosylphosphatidylinositol (GPI) anchor assembly the de-N-acetylation of the N-acetylglucosaminylphosphatidylinositol intermediate functional homolog of human PIG-Lp
weakly similar to uniprot|P22136 Saccharomyces cerevisiae YMR282C AEP2 Mitochondrial protein likely involved in translation of the mitochondrial OLI1 mRNA exhibits genetic interaction with the OLI1 mRNA 5'-untranslated leader
similar to uniprot|P23796 Saccharomyces cerevisiae YMR283C RIT1 Modifies initiator methionine tRNA to distinguish it from elongator methionine tRNA Initiator methionine tRNA 2'-O-ribosyl phosphate transferase
highly similar to uniprot|P09938 Saccharomyces cerevisiae YJL026W RNR2 Ribonucleotide-diphosphate reductase (RNR) small subunit the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits
weakly similar to uniprot|O00033 Saccharomyces cerevisiae YOR078W BUD21 Component of small ribosomal subunit (SSU) processosome that contains U3 snoRNA originally isolated as bud-site selection mutant that displays a random budding pattern
some similarities with uniprot|Q12067 Saccharomyces cerevisiae YOR079C ATX2 Golgi membrane protein involved in manganese homeostasis overproduction suppresses the sod1 (copper zinc superoxide dismutase) null mutation
similar to gnl|GLV|CAGL0K05599g Candida glabrata CAGL0K05599g and weakly similar to YOR080W uniprot|Q7LGN4 Saccharomyces cerevisiae YOR080W DIA2 Protein of unknown function involved in invasive and pseudohyphal growth
similar to uniprot|P36165 YKR089C Saccharomyces cerevisiae STC1 Protein of unknown function found in lipid particles potential Cdc28p substrate
weakly similar to uniprot|P36166 Saccharomyces cerevisiae YKR090W PXL1 LIM domain-containing protein that localizes to sites of polarized growth
weakly similar to uniprot|Q12416 Saccharomyces cerevisiae YOR083W WHI5 Protein that regulates the critical cell size required for passage through Start and commitment to cell division may act upstream of SCB binding factor (SBF) and MCB binding factor (MBF) periodically expressed in G1
similar to uniprot|Q12405 Saccharomyces cerevisiae YOR084W Putative lipase of the peroxisomal matrix transcriptionally activated by Yrm1p along with genes involved in multidrug resistance
some similarities with uniprot|P32583 Saccharomyces cerevisiae YKR092C SRP40 Suppressor of mutant AC40 subunit of RNA polymerase I and III nucleolar protein that is immunologically and structurally related to rat Nopp140 a nonribosomal protein of the nucleolus and coiled bodies
highly similar to uniprot|Q00578 Saccharomyces cerevisiae YIL143C SSL2
similar to uniprot|P40460 Saccharomyces cerevisiae YIL144W TID3 Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p) conserved coiled-coil protein involved in chromosome segregation spindle checkpoint activity kinetochore assembly and clustering
similar to uniprot|P40088 Saccharomyces cerevisiae YER145C FTR1 High affinity iron permease involved in the transport of iron across the plasma membrane forms complex with Fet3p expression is regulated by iron
highly similar to uniprot|Q74ZR8 Ashbya gossypii AGR130W AGR130Wp and similar to YER146W uniprot|P40089 Saccharomyces cerevisiae YER146W LSM5 Component of small nuclear ribonucleoprotein complexes involved in RNA processing splicing and decay
similar to uniprot|P38954 Saccharomyces cerevisiae YDR072C IPT1 Inositolphosphotransferase 1 involved in synthesis of mannose-(inositol-P)2-ceramide (M(IP)2C) which is the most abundant sphingolipid in cells mutation confers resistance to the antifungals syringomycin E and DmAMP1 in some growth media
similar to gnl|GLV|CAGL0G05329g Candida glabrata CAGL0G05329g and some similarites with YDR073W uniprot|P38956 Saccharomyces cerevisiae YDR073W SNF11 component of SWI/SNF global transcription activator complex
uniprot|Q9P4D3 Zygosaccharomyces rouxii TPS2 Trehalose-6- phosphate phosphatase and similar to YDR074W uniprot|P31688 Saccharomyces cerevisiae YDR074W TPS2 Trehalose-6- phosphate phosphatase
similar to uniprot|P40090 Saccharomyces cerevisiae YER147C SCC4
highly similar to uniprot|P13393 Saccharomyces cerevisiae YER148W SPT15 TATA-binding protein general transcription factor that interacts with other factors to form the preinitiation complex at promoters essential for viability
weakly similar to uniprot|Q70DD8 Saccharomyces cerevisiae YER149C PEA2 Coiled-coil polarisome protein required for polarized morphogenesis cell fusion and low affinity Ca2 influx forms polarisome complex with Bni1p Bud6p and Spa2p localizes to sites of polarized growth
highly similar to uniprot|P32345 Saccharomyces cerevisiae YDR075W PPH3 Catalytic subunit of protein phosphatase involved in activation of Gln3p which is a transcription factor with a role in nitrogen utilization
weakly similar to uniprot|P38953 Saccharomyces cerevisiae YDR076W RAD55 Protein that stimulates strand exchange by stabilizing the binding of Rad51p to single-stranded DNA involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis forms heterodimer with Rad57p
some similarities with uniprot|Q01589 Saccharomyces cerevisiae YDR077W SED1 Isolated as a suppressor of an erd2 deletion mutant (ERD2 is the HDEL receptor that sorts ER proteins) SED1 encodes a cell wall protein.
similar to uniprot|P38329 Saccharomyces cerevisiae YBR235W Hypothetical ORF
highly similar to uniprot|P32783 Saccharomyces cerevisiae YBR236C ABD1 Methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to the GpppN terminus of capped mRNA
similar to uniprot|P21372 Saccharomyces cerevisiae YBR237W PRP5 RNA helicase in the DEAD-box family
similar to uniprot|P53139 Saccharomyces cerevisiae YGL108C Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
similar to uniprot|P38330 Saccharomyces cerevisiae YBR238C Hypothetical ORF
similar to uniprot|P47029 Saccharomyces cerevisiae YJL084C Cytoplasmic protein of unknown function that interacts with Pcl7p phosphorylated in vitro potential Cdc28p substrate
similar to uniprot|P19658 YJL085W Saccharomyces cerevisiae EXO70 Essential 70kDa subunit of the exocyst complex (Sec3p Sec5p Sec6p Sec8p Sec10p Sec15p Exo70p and Exo84p)
similar to uniprot|P09880 YJL087C Saccharomyces cerevisiae TRL1 tRNA ligase
highly similar to gnl|GLV|CAGL0I10791g Candida glabrata CAGL0I10791g and similar to uniprot|P05150 YJL088W Saccharomyces cerevisiae ARG3 Ornithine carbamoyltransferase
weakly similar to uniprot|P36118 Saccharomyces cerevisiae YKR022C Protein required for cell viability
weakly similar to uniprot|P46954 Saccharomyces cerevisiae YJL089W SIP4 Possibly involved in Snf1p regulated transcriptional activation shows homology to DNA binding domain of Gal4p has a leucine zipper motif and acidic region lexA-Sip4p activates transcription
similar to uniprot|P47027 Saccharomyces cerevisiae YJL090C DPB11 Essential BRCT repeat protein required on the prereplicative complex at replication origins for loading DNA polymerases to initiate DNA synthesis also required for S/M checkpoint control
similar to uniprot|P47026 Saccharomyces cerevisiae YJL091C GWT1 Protein involved in the inositol acylation of glucosaminyl phosphatidylinositol (GlcN-PI) to form glucosaminyl(acyl)phosphatidylinositol (GlcN(acyl)PI) an intermediate in the biosynthesis of glycosylphosphatidylinositol (GPI) anchors
similar to uniprot|P12954 Saccharomyces cerevisiae YJL092W HPR5 DNA helicase and DNA-dependent ATPase involved in DNA repair required for proper timing of commitment to meiotic recombination and the transition from Meiosis I to Meiosis II potential Cdc28p substrate
similar to uniprot|P40310 Saccharomyces cerevisiae YJL093C TOK1 Target Of K1 Killer Toxin outward-rectifier potassium channel
similar to uniprot|P40309 Saccharomyces cerevisiae YJL094C KHA1 Putative K /H antiporter
similar to uniprot|Q01389 Saccharomyces cerevisiae YJL095W BCK1 Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinase C signaling pathway which controls cell integrity upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p
mitochondrial 54S ribosomal protein YmL49
similar to gnl|GLV|CAGL0L03542g Candida glabrata CAGL0L03542g and some similarites with YJL096W uniprot|P40858 Saccharomyces cerevisiae YJL096W MRPL49 Mitochondrial ribosomal protein of the large subunit
similar to uniprot|P40857 Saccharomyces cerevisiae YJL097W Protein required for cell viability
similar to uniprot|P36123 Saccharomyces cerevisiae or to YJL098W uniprot|P40856 Saccharomyces cerevisiae YJL098W
some similarities with uniprot|P38765 Saccharomyces cerevisiae YHR029C Hypothetical ORF
similar to uniprot|Q12068 Saccharomyces cerevisiae YOL151W GRE2 NADPH-dependent methylglyoxal reductase (D-lactaldehyde dehydrogenase) stress induced (osmotic ionic oxidative heat shock and heavy metals) regulated by the HOG pathway
similar to uniprot|Q2UJ53 Aspergillus oryzae AO090003001353 Synaptic vesicle transporter SVOP and related transporters and weakly similar to YBR008C uniprot|P38124 Saccharomyces cerevisiae YBR008C FLR1 Plasma membrane multidrug transporter member of the major facilitator superfamily involved in efflux of fluconazole diazaborine benomyl methotrexate and other drugs
weakly similar to uniprot|Q03558 Saccharomyces cerevisiae YHR179W OYE2 Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) homologous to Oye3p with slight differences in ligand binding and catalytic properties may be involved in sterol metabolism
weakly similar to uniprot|P47177 Saccharomyces cerevisiae YJR149W
some similarities with uniprot|O13297 Saccharomyces cerevisiae YPL228W CET1 Interacts with Ceg1p the mRNA capping enzyme alpha subunit removes gamma-phosphate from triphosphate-terminated RNA mRNA capping enzyme beta subunit (80 kDa) RNA 5'-triphosphatase
similar to uniprot|Q08748 Saccharomyces cerevisiae YOR296W Hypothetical ORF
similar to uniprot|Q05024 Saccharomyces cerevisiae YMR233W Interacts with Top1p in 2-hybrid assay.
similar to uniprot|Q08746 Saccharomyces cerevisiae YOR294W RRS1 Essential protein that binds ribosomal protein L11 and is required for nuclear export of the 60S pre-ribosomal subunit during ribosome biogenesis mouse homolog shows altered expression in Huntington's disease model mice
similar to uniprot|Q05670 Saccharomyces cerevisiae YMR232W FUS2 Cytoplasmic protein localized to the shmoo tip required for the alignment of parental nuclei before nuclear fusion during mating
similar to uniprot|P12868 Saccharomyces cerevisiae YMR231W PEP5 Peripheral vacuolar membrane protein required for protein trafficking and vacuole biogenesis forms complex with Pep3p that promotes vesicular docking/fusion reactions in conjunction with SNARE proteins also interacts with Pep7p
highly similar to uniprot|P46784 Saccharomyces cerevisiae YMR230W RPS10B and to uniprot|Q08745 Saccharomyces cerevisiae YOR293W RPS10A Proteins component of the small (40S) ribosomal subunit
similar to uniprot|Q08743 Saccharomyces cerevisiae YOR292C Hypothetical ORF
similar to uniprot|Q12697 Saccharomyces cerevisiae YOR291W Hypothetical ORF
similar to uniprot|Q05022 Saccharomyces cerevisiae YMR229C RRP5 Part of small ribosomal subunit (SSU) processosome containing U3 snoRNA) required for the synthesis of both 18S and 5.8S rRNAs
similar to uniprot|P14908 Saccharomyces cerevisiae YMR228W MTF1 Mitochondrial RNA polymerase sigma-like specificity factor required for promoter recognition interacts with mitochondrial core polymerase Rpo41p imported into mitochondria via a novel process requiring most of the Mtf1p sequence
weakly similar to uniprot|Q05021 Saccharomyces cerevisiae YMR227C TAF7 TFIID subunit (67 kDa) involved in RNA polymerase II transcription initiation
similar to uniprot|P22082 Saccharomyces cerevisiae YOR290C SNF2 involved in the coordinate regulation of phospholipid synthesis transcriptional regulator
highly similar to uniprot|P33416 Saccharomyces cerevisiae YDR258C HSP78 Oligomeric mitochondrial matrix chaperone that cooperates with Ssc1p in mitochondrial thermotolerance after heat shock prevents the aggregation of misfolded matrix proteins component of the mitochondrial proteolysis system
similar to uniprot|P15992 Saccharomyces cerevisiae YBR072W HSP26 Small heat shock protein with chaperone activity that is regulated by a heat induced transition from an inactive oligomeric (24-mer) complex to an active dimer induced by heat upon entry into stationary phase and during sporulation
similar to uniprot|Q12379 Saccharomyces cerevisiae YDR260C SWM1 Spore Wall Maturation 1
similar to uniprot|P52911 Saccharomyces cerevisiae YDR261C EXG2 Exo-1 3-beta-glucanase involved in cell wall beta-glucan assembly may be anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor
weakly similar to uniprot|Q99234 Saccharomyces cerevisiae YOR030W DFG16 Probable multiple transmembrane protein involved in invasive growth upon nitrogen starvation
some similarities with uniprot|Q12331 Saccharomyces cerevisiae YDR262W Hypothetical ORF
some similarities with uniprot|Q12398 Saccharomyces cerevisiae YOR032C HMS1 C2H2 zinc-finger protein with similarity to myc-family transcription factors; overexpression confers hyperfilamentous growth and suppresses the pseudohyphal filamentation defect of a diploid mep1 mep2 homozygous null mutant
highly similar to uniprot|P17423 Saccharomyces cerevisiae YHR025W THR1 homoserine kinase
similar to uniprot|P23968 Saccharomyces cerevisiae YHR026W PPA1 Subunit c'' of the vacuolar ATPase which functions in acidification of the vacuole
similar to uniprot|P38764 Saccharomyces cerevisiae YHR027C RPN1 Non-ATPase base subunit of the 19S regulatory particle of the 26S proteasome may participate in the recognition of several ligands of the proteasome contains a leucine-rich repeat (LRR) domain a site for protein? protein interactions
similar to uniprot|P18962 Saccharomyces cerevisiae YHR028C
highly similar to uniprot|Q00772 Saccharomyces cerevisiae YHR030C SLT2 Suppressor of lyt2 serine/threonine MAP kinase
similar to uniprot|P38766 Saccharomyces cerevisiae YHR031C RRM3 DNA helicase involved in rDNA replication and Ty1 transposition structurally and functionally related to Pif1p
similar to uniprot|P38767 Saccharomyces cerevisiae YHR032W Hypothetical ORF
similar to uniprot|P38779 Saccharomyces cerevisiae YHR052W CIC1 Core interacting component 1 ribosome biogenesis protein
similar to uniprot|P36053 Saccharomyces cerevisiae YKL160W ELF1 Protein of unknown function deletion inhibits Brome mosaic virus expression
similar to uniprot|P00427 Saccharomyces cerevisiae YHR051W COX6 Subunit VI of cytochrome c oxidase which is the terminal member of the mitochondrial inner membrane electron transport chain expression is regulated by oxygen levels
weakly similar to uniprot|P36054 Saccharomyces cerevisiae YKL159C
similar to uniprot|P38778 Saccharomyces cerevisiae YHR050W SMF2 Divalent metal ion transporter
highly similar to gnl|GLV|CAGL0J00385g Candida glabrata CAGL0J00385g and similar to YHR049W uniprot|P38777 Saccharomyces cerevisiae
similar to uniprot|P38776 Saccharomyces cerevisiae YHR048W Hypothetical ORF
highly similar to uniprot|P32454 Saccharomyces cerevisiae YKL157W APE2 Zinc-dependent metallopeptidase yscII and to YHR047C uniprot|P37898 Saccharomyces cerevisiae YHR047C AAP1' Arginine/alanine aminopeptidase
highly similar to uniprot|P38710 Saccharomyces cerevisiae YHR046C INM1 Inositol monophosphatase involved in biosynthesis of inositol and in phosphoinositide second messenger signaling INM1 expression increases in the presence of inositol and decreases upon exposure to antibipolar drugs lithium and valproate
similar to uniprot|P38775 Saccharomyces cerevisiae YHR045W Hypothetical ORF
similar to uniprot|Q6Q5R1 Saccharomyces cerevisiae YDR279W RNH202 Ribonuclease H2 subunit required for RNase H2 activity
highly similar to uniprot|Q05636 Saccharomyces cerevisiae YDR280W RRP45 Ribosomal RNA Processing Putative 3'->5' exoribonuclease component of exosome complex of 3'->5' exonucleases
similar to uniprot|P38774 Saccharomyces cerevisiae YHR044C
similar to uniprot|Q05648 Saccharomyces cerevisiae YDR282C Hypothetical ORF
similar to uniprot|P16603 Saccharomyces cerevisiae YHR042W NCP1 NADP-cytochrome P450 reductase involved in ergosterol biosynthesis associated and coordinately regulated with Erg11p
similar to uniprot|Q05541 Saccharomyces cerevisiae YDR288W NSE3 Essential protein of unknown function
similar to Saccharomyces cerevisiae YDR287W inositol monophosphatase and to YHR046C uniprot|P38710 Saccharomyces cerevisiae YHR046C INM1 Inositol monophosphatase, involved in biosynthesis of inositol and in phosphoinositide second messenger signaling
similar to uniprot|Q05530 Saccharomyces cerevisiae YDR286C Hypothetical ORF
similar to uniprot|P31111 Saccharomyces cerevisiae YDR285W ZIP1 Synaptonemal complex (SC) protein that connects homologous chromosomes partially during zygotene and entirely during pachytene potential Cdc28p substrate synaptonemal complex protein
similar to uniprot|Q05521 Saccharomyces cerevisiae YDR284C DPP1 Diacylglycerol pyrophosphate (DGPP) phosphatase zinc-regulated vacuolar membrane-associated lipid phosphatase dephosphorylates DGPP to phosphatidate (PA) and Pi then PA to diacylglycerol involved in lipid signaling and cell metabolism
highly similar to uniprot|P15442 Saccharomyces cerevisiae YDR283C GCN2 Protein kinase phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation activated by uncharged tRNAs and the Gcn1p-Gcn20p complex
similar to uniprot|P34162 Saccharomyces cerevisiae YHR041C SRB2 RNA polymerase II holoenzyme/mediator subunit
similar to uniprot|Q05543 Saccharomyces cerevisiae YDR289C RTT103 Regulator of Ty1 Transposition regulator of Ty1 Transposition
highly similar to uniprot|Q05549 Saccharomyces cerevisiae YDR291W Hypothetical ORF
similar to uniprot|P32916 Saccharomyces cerevisiae YDR292C SRP101 Signal recognition particle (SRP) receptor - alpha subunit contain GTPase domains involved in SRP-dependent protein targeting interacts with SRP102p
weakly similar to uniprot|P21147 Saccharomyces cerevisiae YGL055W OLE1 Fatty acid desaturase required for monounsaturated fatty acid synthesis and for normal distribution of mitochondria
similar to uniprot|P38772 Saccharomyces cerevisiae YHR040W BCD1 Essential protein required for the accumulation of box C/D snoRNA
similar to uniprot|P48836 Saccharomyces cerevisiae YHR039C-A VMA10 Vacuolar H+ ATPase subunit G of the catalytic (V1) sector
highly similar to uniprot|P38694 Saccharomyces cerevisiae YHR039C MSC7 Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum msc7 mutants are defective in directing meiotic recombination events to homologous chromatids
similar to uniprot|P38771 Saccharomyces cerevisiae YHR038W RRF1 Ribosomal Recycling Factor 1 originally characterized as FIL1 a Factor for Isocitrate Lyase expression mitochondrial ribosome recycling factor
similar to uniprot|P24276 Saccharomyces cerevisiae YDR293C SSD1 Protein with a role in maintenance of cellular integrity interacts with components of the TOR pathway ssd1 mutant of a clinical S. cerevisiae strain displays elevated virulence
highly similar to uniprot|P07275 Saccharomyces cerevisiae YHR037W PUT2 delta-1-pyrroline-5-carboxylate dehydrogenase
similar to uniprot|P38770 Saccharomyces cerevisiae YHR036W Protein required for cell viability
similar to uniprot|Q05567 Saccharomyces cerevisiae YDR294C DPL1 Dihydrosphingosine phosphate lyase regulates intracellular levels of sphingolipid long-chain base phosphates (LCBPs) degrades phosphorylated long chain bases prefers C16 dihydrosphingosine-l-phosphate as a substrate
similar to uniprot|Q06629 Saccharomyces cerevisiae YDR295C
weakly similar to uniprot|P38769 Saccharomyces cerevisiae YHR035W Hypothetical ORF
similar to uniprot|Q06630 Saccharomyces cerevisiae YDR296W MHR1 Protein involved in homologous recombination in mitochondria and in transcription regulation in nucleus binds to activation domains of acidic activators required for recombination-dependent mtDNA partitioning
similar to uniprot|P38992 Saccharomyces cerevisiae YDR297W SUR2 Sphingosine hydroxylase has a role in sphingolipid metabolism catalyses the conversion of sphinganine to phytosphingosine
similar to uniprot|P09457 Saccharomyces cerevisiae YDR298C ATP5 Subunit 5 of the stator stalk of mitochondrial F1F0 ATP synthase which is a large evolutionarily conserved enzyme complex required for ATP synthesis homologous to bovine subunit OSCP (oligomycin sensitivity-conferring protein)
similar to uniprot|P42949 Saccharomyces cerevisiae YJL104W
similar to uniprot|P36124 Saccharomyces cerevisiae YKR029C SET3
similar to uniprot|P32581 Saccharomyces cerevisiae YJL106W IME2 Serine/threonine protein kinase involved in activation of meiosis associates with Ime1p and mediates its stability activates Ndt80p IME2 expression is positively regulated by Ime1p
some similarities with uniprot|P42946 Saccharomyces cerevisiae YJL108C PRM10 Pheromone-regulated protein predicted to have 5 transmembrane segments
similar to uniprot|P42945 Saccharomyces cerevisiae YJL109C UTP10 Nucleolar protein component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
similar to uniprot|P47128 Saccharomyces cerevisiae YJR082C EAF6 Esa1p-associated factor subunit of the NuA4 acetyltransferase complex
similar to uniprot|Q12406 Saccharomyces cerevisiae YPR034W ARP7 Actin-related protein involved in transcriptional regulation subunit of the chromatin remodeling Snf/Swi complex
highly similar to uniprot|P32288 Saccharomyces cerevisiae YPR035W GLN1 Glutamine synthetase (GS) synthesizes glutamine from glutamate and ammonia with Glt1p forms the secondary pathway for glutamate biosynthesis from ammonia expression regulated by nitrogen source and by amino acid limitation
similar to uniprot|P41807 Saccharomyces cerevisiae YPR036W VMA13 vacuolar ATPase V1 domain subunit H (54 kDa)
weakly similar to uniprot|P47130 Saccharomyces cerevisiae YJR084W CSN12 Subunit of the Cop9 signalosome which is required for deneddylation or removal of the ubiquitin-like protein Rub1p from Cdc53p (cullin) involved in adaptation to pheromone signaling
highly similar to uniprot|P47131 Saccharomyces cerevisiae YJR085C Hypothetical ORF
similar to uniprot|P18852 Saccharomyces cerevisiae YJR086W STE18 G protein gamma subunit forms a dimer with Ste4p to activate the mating signaling pathway forms a heterotrimer with Gpa1p and Ste4p to dampen signaling C-terminus is palmitoylated and farnesylated which are required for normal signaling
similar to uniprot|Q12284 Saccharomyces cerevisiae YPR037C ERV2 Flavin-linked sulfhydryl oxidase localized to the endoplasmic reticulum lumen involved in disulfide bond formation within the ER
similar to uniprot|Q12199 Saccharomyces cerevisiae YPR040W TIP41 Protein involved in regulation of the TOR pathway
similar to uniprot|P47133 Saccharomyces cerevisiae YJR088C Hypothetical ORF
highly similar to uniprot|P38431 Saccharomyces cerevisiae YPR041W TIF5 eIF5 mediates hydrolysis of eIF2-GTP (SUI2 SUI3 GCD11) at start codons Translation initiation factor eIF-5
similar to uniprot|P24814 Saccharomyces cerevisiae YJR090C GRR1 F-box protein component of the SCF ubiquitin-ligase complex required for Cln1p and Cln2p degradation involved in carbon catabolite repression glucose-dependent divalent cation transport high-affinity glucose transport and morphogenesis
similar to uniprot|P47135 Saccharomyces cerevisiae YJR091C JSN1 Member of the Puf family of RNA-binding proteins and to uniprot|Q12221 Saccharomyces cerevisiae YPR042C PUF2 mRNA binding protein
some similarities with uniprot|P47136 Saccharomyces cerevisiae YJR092W BUD4 Protein involved in bud-site selection and required for axial budding pattern localizes with septins to bud neck in mitosis and may constitute an axial landmark for next round of budding potential Cdc28p substrate
some similarities with uniprot|P45976 Saccharomyces cerevisiae YJR093C FIP1 Subunit of cleavage polyadenylation factor
similar to uniprot|P43634 Saccharomyces cerevisiae YLR098C CHA4 Zinc-finger protein with Zn[2]-Cys[6] fungal-type binuclear cluster domain; DNA-binding transcriptional activator or CHA1 and to YOR337W uniprot|P47988 Saccharomyces cerevisiae YOR337W TEA1 Mutants are defective in Ty1 Enhancer-mediated Activation Ty1 enhancer activator
weakly similar to uniprot|P21190 Saccharomyces cerevisiae YJR094C IME1 Master regulator of meiosis that is active only during meiotic events activates transcription of early meiotic genes through interaction with Ume6p degraded by the 26S proteasome following phosphorylation by Ime2p
weakly similar to uniprot|P49631 Saccharomyces cerevisiae YPR043W RPL43A Protein component of the large (60S) ribosomal subunit
highly similar to uniprot|P33303 Saccharomyces cerevisiae YJR095W SFC1 Mitochondrial succinate-fumarate transporter transports succinate into and fumarate out of the mitochondrion required for ethanol and acetate utilization
highly similar to uniprot|P47137 Saccharomyces cerevisiae YJR096W
similar to uniprot|P35127 Saccharomyces cerevisiae YJR099W YUH1 Ubiquitin C-terminal hydrolase that cleaves ubiquitin-protein fusions to generate monomeric ubiquitin hydrolyzes the peptide bond at the C-terminus of ubiquitin also the major processing enzyme for the ubiquitin-like protein Rub1p
weakly similar to uniprot|Q07109 Saccharomyces cerevisiae YPR045C Hypothetical ORF
similar to uniprot|P47140 Saccharomyces cerevisiae YJR100C Hypothetical ORF
mitochondrial 37S ribosomal protein RSM26
similar to uniprot|P47141 Saccharomyces cerevisiae YJR101W RSM26 Mitochondrial ribosomal protein of the small subunit
similar to uniprot|P47142 Saccharomyces cerevisiae YJR102C VPS25 Component of the ESCRT-II complex which is involved in ubiquitin-dependent sorting of proteins into the endosome
similar to uniprot|Q12262 Saccharomyces cerevisiae YPR046W MCM16 Protein involved in kinetochore-microtubule mediated chromosome segregation binds to centromere DNA
highly similar to gnl|GLV|CAGL0F04433g Candida glabrata CAGL0F04433g and similar to YBL039C uniprot|P28274 Saccharomyces cerevisiae
highly similar to uniprot|P00445 Saccharomyces cerevisiae YJR104C SOD1 Cu Zn superoxide dismutase some mutations are analogous to those that cause ALS (amyotrophic lateral sclerosis) in humans
similar to uniprot|P18414 Saccharomyces cerevisiae YBL040C ERD2 Integral membrane protein that binds to the HDEL motif in proteins destined for retention in the endoplasmic reticulum has a role in maintenance of normal levels of ER-resident proteins
highly similar to uniprot|P23724 Saccharomyces cerevisiae YBL041W PRE7 20S proteasome beta-type subunit
similar to uniprot|P38196 YBL042C Saccharomyces cerevisiae FUI1 High affinity uridine permease localized to the plasma membrane not involved in uracil transport
similar to uniprot|P07256 Saccharomyces cerevisiae YBL045C COR1 Core subunit of the ubiquinol-cytochrome c reductase complex (bc1 complex) which is a component of the mitochondrial inner membrane electron transport chain
some similarities with uniprot|P38193 Saccharomyces cerevisiae YBL046W Hypothetical ORF
mitochondrial 37S ribosomal protein RSM7
similar to uniprot|P47150 Saccharomyces cerevisiae YJR113C RSM7 Mitochondrial ribosomal protein of the small subunit
weakly similar to uniprot|P34216 Saccharomyces cerevisiae YBL047C EDE1 Key endocytic protein involved in a network of interactions with other endocytic proteins binds membranes in a ubiquitin-dependent manner may also bind ubiquitinated membrane-associated proteins
similar to uniprot|P47149 Saccharomyces cerevisiae YJR112W NNF1 Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to those contacting microtubules required for accurate chromosome segregation
similar to uniprot|P47148 Saccharomyces cerevisiae YJR111C Hypothetical ORF
similar to uniprot|P47147 Saccharomyces cerevisiae YJR110W YMR1 Phosphatidylinositol 3-phosphate
similar to uniprot|P38191 Saccharomyces cerevisiae YBL049W MOH1
highly similar to uniprot|P32602 Saccharomyces cerevisiae YBL050W SEC17
similar to uniprot|P03965 Saccharomyces cerevisiae YJR109C CPA2 Large subunit of carbamoyl phosphate synthetase, which catalyzes a step in the synthesis of citrulline, an arginine precursor
highly similar to gnl|GLV|KLLA0D16412g Kluyveromyces lactis KLLA0D16412g and similar to YJL153C uniprot|P11986 Saccharomyces cerevisiae YJL153C INO1 Inositol 1- phosphate synthase involved in synthesis of inositol phosphates and inositol-containing phospholipids transcription is coregulated with other phospholipid biosynthetic genes by Ino2p and Ino4p which bind the UASINO DNA element
similar to uniprot|P00431 Saccharomyces cerevisiae YKR066C CCP1 Mitochondrial cytochrome-c peroxidase degrades reactive oxygen species in mitochondria involved in the response to oxidative stress
similar to uniprot|P34110 Saccharomyces cerevisiae YJL154C VPS35 Protein involved in vacuolar sorting retromer complex component
highly similar to uniprot|P32604 Saccharomyces cerevisiae YJL155C FBP26 Fructose-2 6-bisphosphatase required for glucose metabolism
similar to uniprot|P47002 Saccharomyces cerevisiae YJL156C SSY5 Component of the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p) which senses external amino acid concentration and transmits intracellular signals that result in regulation of expression of amino acid permease genes
similar to uniprot|P21268 Saccharomyces cerevisiae YJL157C FAR1 Cyclin-dependent kinase inhibitor that mediates cell cycle arrest in response to pheromone also forms a complex with Cdc24p Ste4p and Ste18p that may specify the direction of polarized growth during mating potential Cdc28p substrate
some similarities with uniprot|Q03178 Saccharomyces cerevisiae YKL164C PIR1 Protein containing tandem internal repeats
similar to uniprot|Q03178 Saccharomyces cerevisiae YKL164C PIR1 Protein containing tandem internal repeats
weakly similar to uniprot|P46998 Saccharomyces cerevisiae YJL161W FMP33 The authentic non-tagged protein was localized to the mitochondria
similar to uniprot|Q757X4 Ashbya gossypii AEL112C AEL112Cp and weakly similar to YJL162C uniprot|P46997 Saccharomyces cerevisiae YJL162C JJJ2 Protein that may function as a cochaperone as suggested by the presence of a DnaJ-like domain
highly similar to uniprot|P36051 Saccharomyces cerevisiae YKL165C MCD4 Protein involved in glycosylphosphatidylinositol (GPI) anchor synthesis multimembrane-spanning protein that localizes to the endoplasmic reticulum highly conserved among eukaryotes
similar to gnl|GLV|CAGL0M08426g Candida glabrata CAGL0M08426g and weakly similar to YJL163C uniprot|P46996 Saccharomyces cerevisiae YJL163C Hypothetical ORF
similar to uniprot|P05986 Saccharomyces cerevisiae YKL166C TPK3 Involved in nutrient control of cell growth and division cAMP-dependent protein kinase catalytic subunit and to YJL164C uniprot|P06244 Saccharomyces cerevisiae YJL164C TPK1 putative catalytic subunit of cAMP-dependent protein kinase
mitochondrial 54S ribosomal protein MRP49
similar to uniprot|P32388 Saccharomyces cerevisiae YKL167C MRP49 Mitochondrial ribosomal protein of the large subunit not essential for mitochondrial translation
similar to uniprot|P38970 Saccharomyces cerevisiae YJL165C HAL5 Putative protein kinase overexpression increases sodium and lithium tolerance whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake suggesting a role in regulation of Trk1p and/or Trk2p transporters
mitochondrial 54S ribosomal protein YmL38/YmL34
highly similar to uniprot|P35996 Saccharomyces cerevisiae YKL170W MRPL38 Mitochondrial ribosomal protein of the large subunit appears as two protein spots (YmL34 and YmL38) on two-dimensional SDS gels
similar to uniprot|Q757Y0 Ashbya gossypii AEL120W AEL120Wp and weakly similar to YKL171W uniprot|P36003 Saccharomyces cerevisiae YKL171W Hypothetical ORF
highly similar to uniprot|P08525 Saccharomyces cerevisiae YJL166W QCR8 Ubiquinol cytochrome-c reductase subunit 8
highly similar to uniprot|P08524 Saccharomyces cerevisiae YJL167W ERG20 Farnesyl pyrophosphate synthetase, has both dimethylallyltranstransferase and geranyltranstransferase activities; catalyzes the formation of C15 farnesyl pyrophosphate units for isoprenoid and sterol biosynthesis
highly similar to gnl|GLV|CAGL0L00341g Candida glabrata CAGL0L00341g and highly similar to YKL172W uniprot|P36049 Saccharomyces cerevisiae YKL172W EBP2 Essential protein required for the maturation of 25S rRNA and 60S ribosomal subunit assembly localizes to the nucleolus
similar to uniprot|P36048 Saccharomyces cerevisiae YKL173W SNU114 involved in splicing U5 snRNP-specific protein related to EF-2
similar to uniprot|P36029 Saccharomyces cerevisiae YKL174C TPO5 Protein involved in excretion of putrescine and spermidine putative polyamine transporter in the Golgi or post-Golgi vesicles
similar to uniprot|P34240 Saccharomyces cerevisiae YKL175W ZRT3 Vacuolar membrane zinc transporter transports zinc from storage in the vacuole to the cytoplasm when needed transcription is induced under conditions of zinc deficiency
similar to uniprot|P34239 Saccharomyces cerevisiae YKL176C LST4 Protein possibly involved in a post-Golgi secretory pathway required for the transport of nitrogen-regulated amino acid permease Gap1p from the Golgi to the cell surface
similar to uniprot|P46995 Saccharomyces cerevisiae YJL168C SET2 Histone methyltransferase with a role in transcriptional elongation methylates a lysine residue of histone H3 associates with the C-terminal domain of Rpo21p histone methylation activity is regulated by phosphorylation status of Rpo21p
weakly similar to uniprot|P46993 Saccharomyces cerevisiae YJL170C ASG7 Protein that regulates signaling from a G protein beta subunit Ste4p and its relocalization within the cell specific to a-cells and induced by alpha-factor
similar to uniprot|P06783 Saccharomyces cerevisiae YKL178C STE3 Cell surface a factor receptor transcribed in alpha cells and required for mating by alpha cells couples to MAP kinase cascade to mediate pheromone response ligand bound receptors undergo endocytosis and recycling to the plasma membrane
similar to uniprot|P27614 Saccharomyces cerevisiae YJL172W CPS1 Vacuolar carboxypeptidase yscS expression is induced under low-nitrogen conditions
highly similar to gnl|GLV|CAGL0C00341g Candida glabrata CAGL0C00341g and similar to YJL173C uniprot|P26755 Saccharomyces cerevisiae YJL173C RFA3 Subunit of heterotrimeric Replication Factor A (RF-A) which is a highly conserved single-stranded DNA binding protein involved in DNA replication repair and recombination
highly similar to uniprot|Q08911 Saccharomyces cerevisiae YOR388C FDH1 NAD()-dependent formate dehydrogenase may protect cells from exogenous formate
similar to uniprot|P39005 Saccharomyces cerevisiae YJL174W KRE9 Glycoprotein involved in cell wall beta-glucan assembly null mutation leads to severe growth defects aberrant multibudded morphology and mating defects
highly similar to uniprot|P39940 Saccharomyces cerevisiae YER125W RSP5 Ubiquitin-protein ligase involved in ubiquitin-mediated protein degradation plays a role in heat shock element (HSE)-mediated gene expression and multivesicular body sorting contains a hect (homologous to E6-AP carboxyl terminus) domain
weakly similar to uniprot|P46945 Saccharomyces cerevisiae YGL176C Hypothetical ORF
similar to uniprot|P39016 Saccharomyces cerevisiae YGL178W MPT5 Protein that specifically binds to mRNAs encoding chromatin modifiers and spindle pole body components has roles in longevity in maintenance of cell wall integrity and in sensitivity to and recovery from pheromone arrest
highly similar to uniprot|P40078 Saccharomyces cerevisiae YER126C NSA2 Constituent of 66S pre-ribosomal particles involved in 60S ribosomal subunit biogenesis
similar to uniprot|P40079 Saccharomyces cerevisiae YER127W LCP5 Essential protein involved in maturation of 18S rRNA depletion leads to inhibited pre-rRNA processing and reduced polysome levels localizes primarily to the nucleolus
similar to uniprot|P40080 Saccharomyces cerevisiae YER128W Hypothetical ORF
similar to uniprot|P38990 Saccharomyces cerevisiae YER129W PAK1 Upstream kinase for the SNF1 complex partially redundant function with Elm1p and Tos3p members of this family of kinases have functional orthology with LKB1 a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome and some similarities with YGL179C uniprot|P43637 Saccharomyces cerevisiae YGL179C TOS3 Putative protein kinase, related to and redundant with Elm1p and Pak1p in activating the SNF1 complex
similar to uniprot|P53104 Saccharomyces cerevisiae YGL180W ATG1 Protein serine/threonine kinase required for autophagy and for the cytoplasm-to-vacuole targeting (Cvt) pathway
weakly similar to uniprot|P40956 Saccharomyces cerevisiae YGL181W GTS1 Contains a zinc-finger in the N-terminus and a long Gln-rich region in the C-terminus regulates ultradian rhythm cell size cell cycle lifespan sporulation heat tolerance and multidrug transport
similar to uniprot|P53102 Saccharomyces cerevisiae YGL183C MND1 Protein required for recombination and meiotic nuclear division forms a complex with Hop2p which is involved in chromosome pairing and repair of meiotic double-strand breaks
weakly similar to uniprot|P39959 Saccharomyces cerevisiae YER130C Hypothetical ORF
similar to uniprot|P53101 Saccharomyces cerevisiae YGL184C STR3 Cystathionine beta-lyase converts cystathionine into homocysteine
similar to uniprot|P53100 Saccharomyces cerevisiae YGL185C Putative hydroxyacid dehydrogenase
similar to uniprot|P04037 Saccharomyces cerevisiae YGL187C COX4 Subunit IV of cytochrome c oxidase which is the terminal member of the mitochondrial inner membrane electron transport chain N-terminal 25 residues of precursor are cleaved during mitochondrial import
highly similar to uniprot|P39938 Saccharomyces cerevisiae YGL189C
highly similar to uniprot|Q00362 Saccharomyces cerevisiae YGL190C CDC55 Non-essential regulatory subunit B of protein phosphatase 2A has multiple roles in mitosis and protein biosynthesis found in the nucleus of most cells but also at the bud neck (large-budded cells) and at the bud tip (small-budded cells)
highly similar to uniprot|P32799 Saccharomyces cerevisiae YGL191W COX13 Subunit VIa of cytochrome c oxidase which is the terminal member of the mitochondrial inner membrane electron transport chain not essential for cytochrome c oxidase activity but may modulate activity in response to ATP
similar to uniprot|P41833 Saccharomyces cerevisiae YGL192W IME4 Probable mRNA N6-adenosine methyltransferase that is required for IME1 transcript accumulation and for sporulation expression is induced in starved MATa/MAT alpha diploid cells
highly similar to uniprot|P53096 Saccharomyces cerevisiae YGL194C HOS2 Histone deacetylase required for gene activation via specific deacetylation of lysines in H3 and H4 histone tails subunit of the Set3 complex a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity
similar to uniprot|Q754A1 Ashbya gossypii AFR171W AFR171Wp and some similarites with YDR034C uniprot|P40971 Saccharomyces cerevisiae YDR034C LYS14 Transcriptional activator involved in regulation of genes of the lysine biosynthesis pathway requires 2-aminoadipate semialdehyde as co-inducer
similar to uniprot|P33892 Saccharomyces cerevisiae YGL195W GCN1 Positive regulator of the Gcn2p kinase activity forms a complex with Gcn20p proposed to stimulate Gcn2p activation by an uncharged tRNA
similar to uniprot|P53095 Saccharomyces cerevisiae YGL196W Hypothetical ORF
weakly similar to uniprot|P53094 Saccharomyces cerevisiae YGL197W MDS3 Protein with an N-terminal kelch-like domain putative negative regulator of early meiotic gene expression required with Pmd1p for growth under alkaline conditions
similar to uniprot|P53093 Saccharomyces cerevisiae YGL198W YIP4 Protein that interacts with Rab GTPases computational analysis of large-scale protein-protein interaction data suggests a possible role in vesicle-mediated transport
highly similar to uniprot|P32598 Saccharomyces cerevisiae YER133W GLC7 Catalytic subunit of type 1 serine/threonine protein phosphatase involved in many processes including glycogen metabolism sporulation and mitosis interacts with multiple regulatory subunits predominantly isolated with Sds22p
highly similar to uniprot|P32803 Saccharomyces cerevisiae YGL200C EMP24 Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles which function in ER to Golgi transport
weakly similar to uniprot|P53286 Saccharomyces cerevisiae YGR142W BTN2 Cytosolic coiled-coil protein that modulates arginine uptake interacts with Rhb1p possible role in mediating pH homeostasis between the vacuole and plasma membrane H()-ATPase may have a role in intracellular protein trafficking
similar to uniprot|P53285 Saccharomyces cerevisiae YGR141W VPS62 and similar to uniprot|Q06466 Saccharomyces cerevisiae YPR157W Hypothetical ORF
similar to uniprot|Q753I9 Ashbya gossypii AFR323W AFR323Wp and weakly similar to YGR140W uniprot|P32504 Saccharomyces cerevisiae YGR140W CBF2 Essential kinetochore protein component of the CBF3 multisubunit complex that binds to the CDEIII region of the centromere Cbf2p also binds to the CDEII region possibly forming a different multimeric complex ubiquitinated in vivo
similar to uniprot|P53283 Saccharomyces cerevisiae YGR138C TPO2 Polyamine transport protein
weakly similar to uniprot|P28319 Saccharomyces cerevisiae YKL096W CWP1 Cell wall mannoprotein linked to a beta-1 3- and beta-1 6-glucan heteropolymer through a phosphodiester bond involved in cell wall organization
similar to uniprot|P34246 Saccharomyces cerevisiae YKL098W Hypothetical ORF
similar to uniprot|P34247 Saccharomyces cerevisiae YKL099C UTP11 Nucleolar protein component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
weakly similar to uniprot|P34248 Saccharomyces cerevisiae YKL100C Hypothetical ORF
highly similar to uniprot|Q08920 Saccharomyces cerevisiae YPL178W CBC2 Small subunit of the heterodimeric cap binding complex that also contains Sto1p component of the spliceosomal commitment complex interacts with Npl3p possibly to package mRNA for export from the nucleus contains an RNA-binding motif
similar to uniprot|P37297 Saccharomyces cerevisiae YLR305C STT4 Phosphatidylinositol-4-kinase that functions in the Pkc1p protein kinase pathway required for normal vacuole morphology cell wall integrity and actin cytoskeleton organization
similar to uniprot|P52491 Saccharomyces cerevisiae YLR306W UBC12 Enzyme that mediates the conjugation of Rub1p a ubiquitin-like protein to other proteins related to E2 ubiquitin-conjugating enzymes
similar to uniprot|Q04438 Saccharomyces cerevisiae YMR107W
highly similar to uniprot|P07342 Saccharomyces cerevisiae YMR108W ILV2 Acetolactate synthase catalyses the first common step in isoleucine and valine biosynthesis and is the target of several classes of inhibitors localizes to the mitochondria expression of the gene is under general amino acid control
similar to uniprot|Q04439 Saccharomyces cerevisiae YMR109W MYO5 One of two type I myosins contains proline-rich tail homology 2 (TH2) and SH3 domains MYO5 deletion has little effect on growth but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization and to uniprot|P36006 Saccharomyces cerevisiae YKL129C MYO3
similar to uniprot|P36068 Saccharomyces cerevisiae YKL130C SHE2 RNA-binding protein that binds specific mRNAs and interacts with She3p part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud
weakly similar to uniprot|Q04461 Saccharomyces cerevisiae YMR111C Hypothetical ORF
similar to uniprot|Q99278 Saccharomyces cerevisiae YMR112C MED11 14 Kd mediator subunit of RNA polymerase II holoenzyme
similar to uniprot|Q12676 Saccharomyces cerevisiae YMR113W FOL3 Dihydrofolate synthetase involved in folic acid biosynthesis catalyzes the conversion of dihydropteroate to dihydrofolate in folate coenzyme biosynthesis
similar to uniprot|Q04471 Saccharomyces cerevisiae YMR114C Hypothetical ORF
similar to uniprot|Q04472 Saccharomyces cerevisiae YMR115W FMP24 The authentic non-tagged protein was localized to the mitochondria
similar to uniprot|P35999 Saccharomyces cerevisiae YKL134C OCT1 Mitochondrial intermediate peptidase cleaves N-terminal residues of a subset of proteins upon import after their cleavage by mitochondrial processing peptidase (Mas1p-Mas2p) may contribute to mitochondrial iron homeostasis
highly similar to uniprot|P38011 Saccharomyces cerevisiae YMR116C ASC1 WD repeat protein (G-beta like protein) involved in translation regulation required for repression of Gcn4p activity in the absence of amino-acid starvation core component of the ribosome ortholog of mammalian RACK1
highly similar to uniprot|P36000 Saccharomyces cerevisiae YKL135C APL2 Beta-adaptin large subunit of the clathrin-associated protein (AP-1) complex
similar to uniprot|P36064 Saccharomyces cerevisiae YKL137W Hypothetical ORF
mitochondrial 54S ribosomal protein YmL31
similar to uniprot|P14063 Saccharomyces cerevisiae YKL138C MRPL31 Mitochondrial ribosomal protein of the large subunit
similar to uniprot|Q04477 Saccharomyces cerevisiae YMR117C SPC24 Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p) involved in chromosome segregation spindle checkpoint activity and kinetochore clustering
similar to uniprot|Q03957 Saccharomyces cerevisiae YKL139W CTK1 Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) which phosphorylates the C- terminal repeated domain of the RNA polymerase II large subunit (Rpo21p) to affect both transcription and pre-mRNA 3' end processing
similar to uniprot|P34163 Saccharomyces cerevisiae YKL140W TGL1 Steryl ester hydrolase one of three gene products (Yeh1p Yeh2p Tgl1p) responsible for steryl ester hydrolase activity and involved in sterol homeostasis localized to lipid particle membranes
similar to uniprot|P33421 Saccharomyces cerevisiae YKL141W SDH3 Cytochrome b subunit of succinate dehydrogenase (Sdh1p Sdh2p Sdh3p Sdh4p) which couples the oxidation of succinate to the transfer of electrons to ubiquinone and some similarites with YMR118C uniprot|Q04487 Saccharomyces cerevisiae YMR118C Hypothetical ORF, member of GLR.231
weakly similar to uniprot|Q06449 Saccharomyces cerevisiae YPR154W PIN3 Protein that induces appearance of [PIN ] prion when overproduced
similar to uniprot|P39929 Saccharomyces cerevisiae YLR025W SNF7 Involved in derepression of SUC2 in response to glucose limitation involved in glucose derepression
similar to uniprot|Q01590 Saccharomyces cerevisiae YLR026C SED5 Sed5p is a t-SNARE (soluble NSF attachment protein receptor) required in ER to Golgi transport
some similarities with uniprot|P47045 Saccharomyces cerevisiae YJL054W TIM54 Translocase Inner Membrane 54kD Translocase for the insertion of proteins into the mitochondrial inner membrane.
similar to uniprot|P47044 Saccharomyces cerevisiae YJL055W Hypothetical ORF
similar to uniprot|Q02895 Saccharomyces cerevisiae YPL088W Putative aryl alcohol dehydrogenase transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance
weakly similar to uniprot|P47043 Saccharomyces cerevisiae YJL056C ZAP1 Zinc-regulated transcription factor binds to zinc-responsive promoter elements to induce transcription of certain genes in the presence of zinc regulates its own transcription contains seven zinc- finger domains
similar to uniprot|P38347 YBR271W Saccharomyces cerevisiae Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family
similar to uniprot|P47042 Saccharomyces cerevisiae YJL057C probable serine/threonine kinase
similar to uniprot|P38346 Saccharomyces cerevisiae YBR270C BIT2 Hypothetical ORF
similar to uniprot|P47040 Saccharomyces cerevisiae YJL059W YHC3 Homolog of human CLN3 vacuolar/lysosomal membrane protein
highly similar to uniprot|P47039 Saccharomyces cerevisiae YJL060W BNA3 Arylformamidase involved in biosynthesis of nicotinic acid from tryptophan via kynurenine pathway potential Cdc28p substrate
similar to uniprot|P38345 Saccharomyces cerevisiae YBR269C FMP21 The authentic non-tagged protein was localized to the mitochondria
similar to uniprot|P40368 Saccharomyces cerevisiae YJL061W NUP82 Subunit of the nuclear pore complex (NPC) forms a subcomplex with Nup159p and Nsp1p interacts with Nup116p and is required for proper localization of Nup116p in the NPC
similar to uniprot|P36532 Saccharomyces cerevisiae YBR268W MRPL37 Mitochondrial ribosomal protein of the large subunit
similar to uniprot|P40367 Saccharomyces cerevisiae YJL062W LAS21 Integral plasma membrane protein involved in the synthesis of the glycosylphosphatidylinositol (GPI) core structure mutations affect cell wall integrity
similar to uniprot|P38344 Saccharomyces cerevisiae YBR267W REI1 Protein of unknown function involved in bud growth in the mitotic signaling network proposed negative regulator of Swe1p and Gin4p contains dispersed C2H2 zinc finger domains
similar to uniprot|P38342 Saccharomyces cerevisiae YBR265W TSC10 catalyzes the second step in the synthesis of phytosphingosine 3-ketosphinganine reductase
similar to uniprot|Q3E7B2 Saccharomyces cerevisiae YJL062W-A Hypothetical ORF
mitochondrial 54S ribosomal protein YmL8
similar to uniprot|P22353 Saccharomyces cerevisiae YJL063C MRPL8 Mitochondrial ribosomal protein of the large subunit
similar to uniprot|P53206 Saccharomyces cerevisiae YGR012W Hypothetical ORF
similar to uniprot|P38148 Saccharomyces cerevisiae YBR276C PPS1 Protein phosphatase with specificity for serine threonine and tyrosine residues has a role in the DNA synthesis phase of the cell cycle
similar to gnl|GLV|KLLA0F01859g Kluyveromyces lactis KLLA0F01859g and some similarites with YBR278W uniprot|P27344 Saccharomyces cerevisiae YBR278W DPB3 Third-largest subunit of DNA polymerase II (DNA polymerase epsilon) required to maintain fidelity of chromosomal replication and also for inheritance of telomeric silencing mRNA abundance peaks at the G1/S boundary of the cell cycle
similar to gnl|GLV|KLLA0F01881g Kluyveromyces lactis KLLA0F01881g and weakly similar to YJL066C uniprot|P40364 Saccharomyces cerevisiae YJL066C MPM1 Mitochondrial membrane protein of unknown function contains no hydrophobic stretches
similar to uniprot|P38351 Saccharomyces cerevisiae YBR279W PAF1 RNA polymerase II-associated protein defines a large complex that is biochemically and functionally distinct from the Srb-Mediator form of Pol II holoenzyme and is required for full expression of a subset of cell cycle-regulated genes
similar to uniprot|P40363 Saccharomyces cerevisiae YJL068C Hypothetical ORF
similar to uniprot|P38352 Saccharomyces cerevisiae YBR280C Hypothetical ORF
similar to uniprot|P38149 Saccharomyces cerevisiae YBR281C Hypothetical ORF
similar to uniprot|P40362 Saccharomyces cerevisiae YJL069C UTP18 Possible U3 snoRNP protein involved in maturation of pre-18S rRNA based on computational analysis of large-scale protein-protein interaction data
mitochondrial 54S ribosomal protein YmL27
highly similar to gnl|GLV|CAGL0B03267g Candida glabrata CAGL0B03267g and similar to YBR282W uniprot|P36526 Saccharomyces cerevisiae YBR282W MRPL27 Mitochondrial ribosomal protein of the large subunit
highly similar to uniprot|P38353 Saccharomyces cerevisiae YBR283C SSH1 Subunit of the Ssh1 translocon complex Sec61p homolog involved in co-translational pathway of protein translocation not essential
similar to uniprot|P40361 Saccharomyces cerevisiae YJL070C and to uniprot|P38150 Saccharomyces cerevisiae YBR284W Hypothetical ORFs
similar to uniprot|P40360 Saccharomyces cerevisiae YJL071W ARG2 Acetylglutamate synthase (glutamate N-acetyltransferase) mitochondrial enzyme that catalyzes the first step in the biosynthesis of the arginine precursor ornithine forms a complex with Arg5 6p
highly similar to uniprot|P40359 Saccharomyces cerevisiae YJL072C PSF2 Subunit of the GINS complex (Sld5p Psf1p Psf2p Psf3p) which binds to DNA replication origins and facilitates assembly of the DNA replication machinery
highly similar to uniprot|P40359 Saccharomyces cerevisiae YJL072C
similar to uniprot|P37302 Saccharomyces cerevisiae YBR286W APE3 Vacuolar aminopeptidase Y processed to mature form by Prb1p
weakly similar to uniprot|P40358 Saccharomyces cerevisiae YJL073W JEM1 DnaJ-like chaperone required for nuclear membrane fusion during mating localizes to the ER membrane exhibits genetic interactions with KAR2
similar to uniprot|P38355 Saccharomyces cerevisiae YBR287W ZSP1
similar to uniprot|P47037 Saccharomyces cerevisiae YJL074C SMC3 Subunit of the multiprotein cohesin complex required for sister chromatid cohesion in mitotic cells also required with Rec8p for cohesion and recombination during meiosis phylogenetically conserved SMC chromosomal ATPase family member
some similarities with uniprot|P47035 Saccharomyces cerevisiae YJL076W NET1 Core subunit of the RENT complex which is a complex involved in nucleolar silencing and telophase exit stimulates transcription by RNA polymerase I and regulates nucleolar structure
some similarities with uniprot|P36110 Saccharomyces cerevisiae YKR013W PRY2 Protein of unknown function, has similarity to Pry1p and Pry3p and to the plant PR-1 class of pathogen related proteins
similar to uniprot|P06105 Saccharomyces cerevisiae YJL080C SCP160 May be required during cell division for faithful partitioning of the ER-nuclear envelope membranes involved in control of mitotic chromosome transmission
highly similar to uniprot|Q75F92 Ashbya gossypii AAL176C AAL176Cp and similar to YKR014C uniprot|P36018 Saccharomyces cerevisiae YKR014C YPT52 rab5-like GTPase involved in vacuolar protein sorting and endocytosis probable purine nucleotide-binding protein
similar to uniprot|P36112 Saccharomyces cerevisiae YKR016W FMP13 The authentic non-tagged protein was localized to the mitochondria
highly similar to uniprot|P80428 Saccharomyces cerevisiae YJL081C ARP4 Nuclear actin-related protein involved in chromatin remodeling component of chromatin-remodeling enzyme complexes
similar to uniprot|P36113 Saccharomyces cerevisiae YKR017C Hypothetical ORF
highly similar to uniprot|P36114 Saccharomyces cerevisiae YKR018C Hypothetical ORF
weakly similar to YJL083W, uniprot|P47030 Saccharomyces cerevisiae YJL083W (TAX4)
similar to uniprot|P36116 Saccharomyces cerevisiae YKR020W VPS51 whiskey (whi) mutant forms a tetramer with VPS52 VPS53 and VPS54
highly similar to gnl|GLV|CAGL0F07491g Candida glabrata CAGL0F07491g and similar to uniprot|P53141 Saccharomyces cerevisiae YGL106W MLC1 Essential light chain for myosin Myo2p may stabilize Myo2p by binding to the neck region may interact with Myo1p Iqg1p and Myo2p to coordinate formation and contraction of the actomyosin ring with targeted membrane deposition
similar to uniprot|P38140 Saccharomyces cerevisiae YBR239C Hypothetical ORF
similar to uniprot|P46672 Saccharomyces cerevisiae YGL105W ARC1 Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases (Mes1p and Gus1p) delivering tRNA to them stimulating catalysis and ensuring their localization to the cytoplasm also binds quadruplex nucleic acids
weakly similar to uniprot|P38141 Saccharomyces cerevisiae YBR240C THI2 Zinc finger protein of the Zn(II)2Cys6 type probable transcriptional activator of thiamine biosynthetic genes
similar to uniprot|P38142 Saccharomyces cerevisiae YBR241C Hypothetical ORF
highly similar to uniprot|P02406 Saccharomyces cerevisiae YGL103W RPL28 Ribosomal protein L29 of the large (60S) ribosomal subunit
highly similar to gnl|GLV|CAGL0J10362g Candida glabrata CAGL0J10362g and similar to YBR242W uniprot|P38331 Saccharomyces cerevisiae YBR242W Hypothetical ORF or YGL101W uniprot|P53144 Saccharomyces cerevisiae YGL101W Hypothetical ORF
highly similar to uniprot|P07286 Saccharomyces cerevisiae YBR243C ALG7 UDP-N-acetyl-glucosamine-1-P transferase transfers Glc-Nac-P from UDP-GlcNac to Dol-P in the ER in the first step of the dolichol pathway of protein asparagine-linked glycosylation inhibited by tunicamycin
highly similar to uniprot|P53011 Saccharomyces cerevisiae YGL100W SEH1 Nuclear pore protein homologous to Sec13p
highly similar to uniprot|P40581 Saccharomyces cerevisiae YIR037W HYR1 Thiol peroxidase that functions as a hydroperoxide receptor to sense intracellular hydroperoxide levels and transduce a redox signal to the Yap1p transcription factor or YBR244W uniprot|P38143 Saccharomyces cerevisiae YBR244W GPX2 Phospholipid hydroperoxide glutathione peroxidase induced by glucose starvation that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress
similar to uniprot|P38144 Saccharomyces cerevisiae YBR245C ISW1 Member of the imitation-switch (ISWI) class of ATP-dependent chromatin remodeling complexes ATPase that forms a complex with Ioc2p and Ioc4p to regulate transcription elongation and a complex with Ioc3p to repress transcription initiation
similar to uniprot|P38332 Saccharomyces cerevisiae YBR246W Hypothetical ORF
similar to uniprot|P53145 Saccharomyces cerevisiae YGL099W LSG1 Putative GTPase involved in 60S ribosomal subunit biogenesis localized to the cytoplasm
similar to uniprot|P53146 Saccharomyces cerevisiae YGL098W USE1 Use1p is a SNARE and forms a complex with the SNAREs Sec22p Sec20p and Ufe1p. The protein is localized to the ER and use1 mutants show defects in retrograde traffic from the Golgi to the ER Protein required for cell viability
weakly similar to uniprot|Q04301 Saccharomyces cerevisiae YMR088C VBA1 Permease of basic amino acids in the vacuolar membrane
similar to uniprot|P38333 Saccharomyces cerevisiae YBR247C ENP1 Protein associated with U3 and U14 snoRNAs required for pre-rRNA processing and 40S ribosomal subunit synthesis localized in the nucleus and concentrated in the nucleolus
highly similar to uniprot|P21827 Saccharomyces cerevisiae YGL097W SRM1 Nucleotide exchange factor for Gsp1p localizes to the nucleus required for nucleocytoplasmic trafficking of macromolecules potentially phosphorylated by Cdc28p
highly similar to uniprot|P33734 Saccharomyces cerevisiae YBR248C HIS7 Imidazole glycerol phosphate synthase (glutamine amidotransferase:cyclase) catalyzes the fifth and sixth steps of histidine biosynthesis and also produces 5-aminoimidazole-4-carboxamide ribotide (AICAR) a purine precursor
highly similar to uniprot|P32449 Saccharomyces cerevisiae YBR249C ARO4 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase
weakly similar to uniprot|P33757 Saccharomyces cerevisiae YBR250W Hypothetical ORF
some similarities with uniprot|P41817 Saccharomyces cerevisiae YPL177C CUP9 Homeodomain-containing transcriptional repressor of PTR2 which encodes a major peptide transporter imported peptides activate ubiquitin-dependent proteolysis resulting in degradation of Cup9p and de-repression of PTR2 transcription
highly similar to uniprot|P19414 Saccharomyces cerevisiae YLR304C ACO1 Mitochondrial aconitase required for the tricarboxylic acid (TCA) cycle mutation leads to glutamate auxotrophy
similar to uniprot|P14772 Saccharomyces cerevisiae YLL015W BPT1 ABC type transmembrane transporter of MRP/CFTR family found in vacuolar membrane involved in the transport of unconjugated bilirubin and in heavy metal detoxification via glutathione conjugates along with Ycf1p
highly similar to uniprot|P06106 Saccharomyces cerevisiae YLR303W MET17 O-acetyl homoserine-O-acetyl serine sulfhydrylase required for sulfur amino acid synthesis
highly similar to uniprot|P53290 Saccharomyces cerevisiae YGR163W GTR2 Cytoplasmic GTP binding protein functions as a negative regulator of the Ran/Tc4 GTPase cycle downstream of its binding partner and homolog Gtr1p homolog of human RagC and RagD proteins
similar to uniprot|P53177 Saccharomyces cerevisiae YGL050W Hypothetical ORF
some similarities with uniprot|P39935 Saccharomyces cerevisiae YGR162W TIF4631 also called eIF4 (eIF-4) gamma mRNA cap-binding protein (eIF-4F) 150K subunit highly homologous to Tif4632p homologs of mammalian p220
highly similar to uniprot|Q01939 Saccharomyces cerevisiae YGL048C RPT6 One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates bound by ubiquitin-protein ligases Ubr1p and Ufd4p localized mainly to the nucleus throughout the cell cycle
similar to uniprot|P53178 Saccharomyces cerevisiae YGL047W
similar to uniprot|P05066 Saccharomyces cerevisiae YOR386W PHR1 DNA photolyase involved in photoreactivation repairs pyrimidine dimers in the presence of visible light induced by DNA damage regulated by transcriptional repressor Rph1p
similar to uniprot|P06115 Saccharomyces cerevisiae YGR088W CTT1 Cytosolic catalase T has a role in protection from oxidative damage by hydrogen peroxide
similar to uniprot|O59822 Schizosaccharomyces pombe SPCC1840 SPCC965.02 protein and weakly similar to YJL212C uniprot|P40897 Saccharomyces cerevisiae YJL212C OPT1 Plasma membrane transporter that transports tetra- and pentapeptides and glutathione member of the OPT family
similar to uniprot|P53047 Saccharomyces cerevisiae YGR213C RTA1 involved in 7-aminocholesterol resistance
weakly similar to uniprot|P39961 Saccharomyces cerevisiae YER184C Hypothetical ORF
similar to uniprot|Q2US70 Aspergillus oryzae AO090005000547 Predicted protein