Zygosaccharomyces rouxii strain CBS732 chromosome F complete sequence.
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Zygosaccharomyces.
Comparative genomics of protoploid Saccharomycetaceae
Submitted (25-SEP-2017) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (04-JUN-2009) Genoscope - Centre National de Sequencage : BP 191 91006 EVRY cedex - FRANCE (E-mail : seqref@genoscope.cns.fr - Web : www.genoscope.cns.fr)
PROVISIONAL REFSEQ: This record has not yet been subject to final\nNCBI review. The reference sequence is identical to CU928178.\nThe Zygosaccharomyces rouxii sequence is made of 7 chromosomes (A\nto G). The sequence was annotated by the Genolevures Consortium.\nFor more information go to\nhttp://cbi.labri.fr/Genolevures.\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: INSDC submitter\nAnnotation Status :: Full annotation\nAnnotation Pipeline :: Eukaryotic Annotation Propagation Pipeline\n##Genome-Annotation-Data-END##
weakly similar to uniprot|P32768 Saccharomyces cerevisiae YAR050W
similar to uniprot|Q0CZS0 Aspergillus terreus NIH2624 ATEG_00814 Hypothetical protein
similar to uniprot|P40445 Saccharomyces cerevisiae YIL166C
similar to uniprot|Q12358 Saccharomyces cerevisiae YLL057C JLP1 similar to Fe(II)-dependent sulfonate/alpha-ketoglutarate dioxygenase
highly similar to uniprot|P41819 Saccharomyces cerevisiae YPL266W DIM1 Essential 18S rRNA dimethylase responsible for conserved m6(2)Am6(2)A dimethylation in 3'-terminal loop of 18 S rRNA part of 90S and 40S pre-particles in nucleolus involved in pre-ribosomal RNA processing
similar to uniprot|Q08981 Saccharomyces cerevisiae YPL267W ACM1 Protein of unknown function potential Cdc28p substrate
similar to uniprot|P32383 Saccharomyces cerevisiae YPL268W PLC1 Phosphoinositide-specific phospholipase C hydrolyzes phosphatidylinositol 4 5-biphosphate (PIP2) to generate inositol 1 4 5-triphosphate (IP3) and 1 2-diacylglycerol (DAG) involved in kinetochore function and pseudohyphal differentiation
similar to gnl|GLV|CAGL0A01155g Candida glabrata CAGL0A01155g and weakly similar to YPL269W uniprot|P32526 Saccharomyces cerevisiae YPL269W KAR9 Karyogamy protein required for correct positioning of the mitotic spindle and for orienting cytoplasmic microtubules localizes at the shmoo tip in mating cells and at the tip of the growing bud in small-budded cells through anaphase
similar to uniprot|P33311 Saccharomyces cerevisiae YPL270W MDL2 Half-type ATP-binding cassette (ABC) transporter of the inner mitochondrial membrane
similar to uniprot|P21306 Saccharomyces cerevisiae YPL271W ATP15 Epsilon subunit of the F1 sector of mitochondrial F1F0 ATP synthase which is a large evolutionarily conserved enzyme complex required for ATP synthesis
similar to gnl|GLV|CAGL0B03553g Candida glabrata CAGL0B03553g and weakly similar to YEL055C uniprot|P39985 Saccharomyces cerevisiae
similar to uniprot|P39984 Saccharomyces cerevisiae YEL056W
similar to uniprot|Q08979 Saccharomyces cerevisiae YPL263C KEL3 Cytoplasmic protein of unknown function
similar to uniprot|P38628 Saccharomyces cerevisiae YEL058W PCM1 Essential N-acetylglucosamine-phosphate mutase a hexosephosphate mutase involved in the biosynthesis of chitin
similar to uniprot|Q05676 Saccharomyces cerevisiae YEL059C-A
similar to uniprot|Q06674 Saccharomyces cerevisiae YDR317W Hypothetical ORF
similar to uniprot|Q04660 Saccharomyces cerevisiae YMR049C ERB1 Protein required for maturation of the 25S and 5.8S ribosomal RNAs homologous to mammalian Bop1
some similarities with uniprot|Q04659 Saccharomyces cerevisiae YMR048W CSM3 Protein required for accurate chromosome segregation during meiosis
some similarities with uniprot|Q02630 Saccharomyces cerevisiae YMR047C NUP116 Subunit of the nuclear pore complex (NPC) that is localized to both sides of the pore contains a repetitive GLFG motif that interacts with mRNA export factor Mex67p and with karyopherin Kap95p homologous to Nup100p
weakly similar to uniprot|Q04213 Saccharomyces cerevisiae YMR044W IOC4 Member of a complex (Isw1b) with Isw1p and Ioc2p that exhibits nucleosome-stimulated ATPase activity and acts within coding regions to coordinate transcription elongation with termination and processing contains a PWWP motif
similar to uniprot|Q75DC9 Ashbya gossypii ABR098C ABR098Cp and some similarites with YMR043W uniprot|P11746 Saccharomyces cerevisiae YMR043W MCM1 Transcription factor involved in cell-type-specific transcription and pheromone response plays a central role in the formation of both repressor and activator complexes
similar to uniprot|P07249 Saccharomyces cerevisiae YMR042W ARG80 Transcription factor involved in regulation of arginine-responsive genes acts with Arg81p and Arg82p
highly similar to uniprot|P36010 Saccharomyces cerevisiae YKL067W YNK1 Nucleoside diphosphate kinase catalyzes the phosphorylation of nucleoside diphosphates into the corresponding triphosphates for nucleic acid biosynthesis
similar to uniprot|Q04212 Saccharomyces cerevisiae YMR041C Hypothetical ORF
similar to uniprot|P35723 Saccharomyces cerevisiae YKL065C YET1 Endoplasmic reticulum transmembrane protein homolog of human BAP31 protein
similar to uniprot|P54000 Saccharomyces cerevisiae YMR039C SUB1 Suppressor of TFIIB mutations transcriptional coactivator
similar to uniprot|P35724 Saccharomyces cerevisiae YKL064W
similar to uniprot|P40202 Saccharomyces cerevisiae YMR038C CCS1 Copper chaperone for superoxide dismutase Sod1p involved in oxidative stress protection Met-X-Cys-X2-Cys motif within the N-terminal portion is involved in insertion of copper into Sod1p under conditions of copper deprivation
weakly similar to uniprot|P35725 Saccharomyces cerevisiae YKL063C Hypothetical ORF
similar to uniprot|P33749 Saccharomyces cerevisiae YKL062W MSN4 Transcriptional activator related to Msn2p activated in stress conditions which results in translocation from the cytoplasm to the nucleus binds DNA at stress response elements of responsive genes inducing gene expression
similar to uniprot|P32801 Saccharomyces cerevisiae YKL048C ELM1 Serine/threonine protein kinase that regulates cellular morphogenesis septin behavior and cytokinesis required for the regulation of other kinases forms part of the bud neck ring
some similarities with uniprot|P23748 Saccharomyces cerevisiae YMR036C MIH1 Protein tyrosine phosphatase involved in cell cycle control regulates the phosphorylation state of Cdc28p homolog of S. pombe cdc25
highly similar to uniprot|P46972 Saccharomyces cerevisiae YMR035W IMP2 mitochondrial peptidase
similar to uniprot|Q05131 Saccharomyces cerevisiae YMR034C Hypothetical ORF
similar to uniprot|Q05123 Saccharomyces cerevisiae YMR033W ARP9 Actin-related protein involved in transcriptional regulation; subunit of the chromatin remodeling Snf/Swi complex
highly similar to uniprot|P36012 Saccharomyces cerevisiae YKL049C CSE4 Centromere protein that resembles histones required for proper kinetochore function homolog of human CENP-A
similar to uniprot|Q05080 Saccharomyces cerevisiae YMR032W HOF1 Bud neck-localized SH3 domain-containing protein required for cytokinesis
similar to uniprot|Q05050 Saccharomyces cerevisiae YMR031C Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
similar to uniprot|P35735 Saccharomyces cerevisiae YKL051W
some similarities with uniprot|P35734 Saccharomyces cerevisiae YKL052C ASK1 Component of the DASH complex that binds to microtubules and kinetochores and is essential for chromosome segregation phosphorylated during the cell cycle by cyclin-dependent kinases
similar to uniprot|P28817 YDR036C Saccharomyces cerevisiae EHD3 Protein of unconfirmed function plays an indirect role in endocytic membrane trafficking member of a family of enoyl-CoA hydratase/isomerases
similar to uniprot|P38237 YBR058C Saccharomyces cerevisiae UBP14 Ubiquitin-specific protease that specifically disassembles unanchored ubiquitin chains
similar to uniprot|P38236 YBR057C Saccharomyces cerevisiae MUM2 Cytoplasmic protein essential for meiotic DNA replication and sporulation
highly similar to uniprot|P14843 YDR035W Saccharomyces cerevisiae ARO3 3-deoxy-D-arabino-heptulosonate-7- phosphate (DAHP) synthase
similar to uniprot|P38081 YBR056W Saccharomyces cerevisiae Hypothetical ORF
similar to uniprot|P32495 Saccharomyces cerevisiae YDL208W NHP2 Nuclear protein related to mammalian high mobility group (HMG) proteins essential for function of H/ACA-type snoRNPs which are involved in 18S rRNA processing
similar to uniprot|Q03782 Saccharomyces cerevisiae YDR240C SNU56 U1 snRNP protein serine-rich has no counterpart in mammalian U1 snRNP
weakly similar to uniprot|Q03780 Saccharomyces cerevisiae YDR239C Hypothetical ORF
highly similar to uniprot|P41810 Saccharomyces cerevisiae YDR238C SEC26 Involved in endoplasmic-to-Golgi protein trafficking encodes a subunit of yeast coatomer
highly similar to uniprot|P32905 Saccharomyces cerevisiae YGR214W RPS0A protein component of the small (40S) ribosomal subunit
similar to uniprot|Q12209 Saccharomyces cerevisiae YLR047C Hypothetical ORF
similar to uniprot|P53304 Saccharomyces cerevisiae YGR212W SLI1 N-acetyltransferase confers resistance to the sphingolipid biosynthesis inhibitor myriocin (ISP-1) by inactivating it co-operates with Ypk1p in mediating resistance to myriocin converts myriocin into N-acetyl-myriocin
highly similar to uniprot|P53303 Saccharomyces cerevisiae YGR211W ZPR1 Essential protein with two zinc fingers present in the nucleus of growing cells but relocates to the cytoplasm in starved cells via a process mediated by Cpr1p binds to translation elongation factor eEF-1 (Tef1p)
highly similar to uniprot|P42942 Saccharomyces cerevisiae YGR210C Hypothetical ORF
highly similar to uniprot|P06169 Saccharomyces cerevisiae YLR044C PDC1 Major of three pyruvate decarboxylase isozymes key enzyme in alcoholic fermentation decarboxylates pyruvate to acetaldehyde subject to glucose-ethanol- and autoregulation involved in amino acid catabolism and to YLR134W uniprot|P16467 Saccharomyces cerevisiae YLR134W PDC5 Minor isoform of pyruvate decarboxylase, key enzyme in alcoholic fermentation, decarboxylates pyruvate to acetaldehyde, regulation is glucose- and ethanol-dependent, repressed by thiamine, involved in amino acid catabolism
similar to uniprot|P46675 Saccharomyces cerevisiae YLR045C STU2 Microtubule-associated protein (MAP) of the XMAP215/Dis1 family regulates microtubule dynamics during spindle orientation and metaphase chromosome alignment interacts with spindle pole body component Spc72p
highly similar to gnl|GLV|CAGL0K00803g Candida glabrata CAGL0K00803g and similar to YLR043C uniprot|P22217 Saccharomyces cerevisiae YLR043C TRX1 thioredoxin
similar to uniprot|P42941 Saccharomyces cerevisiae YGR208W SER2 phosphoserine phosphatase
similar to uniprot|P53039 Saccharomyces cerevisiae YGR172C YIP1 Golgi integral membrane protein binds to the transport GTPases Ypt1p and Ypt31p
similar to uniprot|P22438 Saccharomyces cerevisiae YGR171C MSM1 Mitochondrial methionyl-tRNA synthetase (MetRS), functions as a monomer in mitochondrial protein synthesis; functions similarly to cytoplasmic MetRS although the cytoplasmic form contains a zinc-binding domain not found in Msm1p
similar to uniprot|P46957 Saccharomyces cerevisiae YJR006W HYS2 DNA polymerase III (delta) 55 kDa subunit essential for cell viability involved in DNA replication and DNA repair
similar to uniprot|P53037 Saccharomyces cerevisiae YGR170W PSD2 Phosphatidylserine decarboxylase of the Golgi and vacuolar membranes converts phosphatidylserine to phosphatidylethanolamine
weakly similar to uniprot|P36119 Saccharomyces cerevisiae YKR023W Hypothetical ORF
similar to uniprot|P42950 Saccharomyces cerevisiae YJL103C Hypothetical ORF
similar to uniprot|P36120 Saccharomyces cerevisiae YKR024C DBP7 Putative ATP-dependent RNA helicase of the DEAD-box family involved in ribosomal biogenesis
similar to uniprot|P36121 Saccharomyces cerevisiae YKR025W RPC37 RNA polymerase III subunit C37
highly similar to uniprot|P14741 Saccharomyces cerevisiae YKR026C GCN3 Alpha subunit of the translation initiation factor eIF2B the guanine-nucleotide exchange factor for eIF2 activity subsequently regulated by phosphorylated eIF2 first identified as a positive regulator of GCN4 expression
similar to uniprot|P39677 Saccharomyces cerevisiae YJL102W MEF2 mitochondrial elongation factor G-like protein
similar to uniprot|P32477 Saccharomyces cerevisiae YJL101C GSH1 Gamma glutamylcysteine synthetase catalyzes the first step in the gamma-glutamyl cycle for glutathione (GSH) biosynthesis expression induced by oxidants cadmium and mercury
similar to uniprot|P42951 Saccharomyces cerevisiae YJL100W LSB6 Phosphatidylinositol 4-kinase that binds Las17p which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization
similar to uniprot|P36122 Saccharomyces cerevisiae YKR027W FMP50 The authentic non-tagged protein was localized to the mitochondria and uniprot|P40955 Saccharomyces cerevisiae YJL099w CHS6 chitin biosynthesis protein
some similarities with uniprot|P43550 Saccharomyces cerevisiae YFL053W DAK2 Dihydroxyacetone kinase, required for detoxification of dihydroxyacetone (DHA); involved in stress adaptation
similar to uniprot|Q07824 Saccharomyces cerevisiae YLL028W TPO1 Proton-motive-force- dependent multidrug transporter of the major facilitator superfamily able to transport eight different compounds including polyamines quinidine cycloheximide and nystatin involved in excess spermidine detoxification
weakly similar to uniprot|Q08909 Saccharomyces cerevisiae YOR385W Hypothetical ORF
similar to gnl|GLV|DEHA0A14894g Debaryomyces hansenii DEHA0A14894g and weakly similar to YLL028W uniprot|Q07824 Saccharomyces cerevisiae YLL028W TPO1 Proton- motive-force-dependent multidrug transporter of the major facilitator superfamily able to transport eight different compounds including polyamines quinidine cycloheximide and nystatin involved in excess spermidine detoxification
similar to uniprot|P32804 Saccharomyces cerevisiae YGL255W ZRT1 High-affinity zinc transporter of the plasma membrane responsible for the majority of zinc uptake transcription is induced under low-zinc conditions by the Zap1p transcription factor
similar to uniprot|Q03102 Saccharomyces cerevisiae YML131W Hypothetical ORF
similar to uniprot|P43554 Saccharomyces cerevisiae YFL049W Hypothetical ORF
similar to uniprot|P43555 Saccharomyces cerevisiae YFL048C EMP47 Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles which function in ER to Golgi transport
similar to uniprot|P43556 Saccharomyces cerevisiae YFL047W RGD2 GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p
weakly similar to uniprot|P38634 Saccharomyces cerevisiae YLR079W SIC1 P40 inhibitor of Cdc28p-Clb5p protein kinase complex
similar to uniprot|P25385 Saccharomyces cerevisiae YLR078C BOS1 v-SNARE (vesicle specific SNAP receptor) localized to the endoplasmic reticulum membrane and necessary for vesicular transport from the ER to the Golgi
similar to uniprot|Q7LI62 Saccharomyces cerevisiae YLR077W FMP25 The authentic non-tagged protein was localized to the mitochondria
highly similar to uniprot|P43557 Saccharomyces cerevisiae YFL046W FMP32 The authentic non-tagged protein was localized to the mitochondria
highly similar to uniprot|P07283 Saccharomyces cerevisiae YFL045C SEC53 involved in synthesis of GDP-mannose and dolichol-phosphate-mannose required for protein assembly in endoplasmic reticulum phosphomannomutase
highly similar to uniprot|P41805 Saccharomyces cerevisiae YLR075W
similar to uniprot|Q08004 Saccharomyces cerevisiae YLR074C BUD20 Protein involved in bud-site selection diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
similar to uniprot|P43558 Saccharomyces cerevisiae YFL044C YOD1 Yeast OTU Deubiquitinating enzyme 1
similar to uniprot|P43560 Saccharomyces cerevisiae YFL042C Due to a sequence change (deletion of G at 46151) YFL043C is now part of YFL042C.
similar to uniprot|P19263 Saccharomyces cerevisiae YLR071C RGR1 Component of RNA polymerase II holoenzyme/mediator complex affects chromatin structure and transcriptional regulation of diverse genes required for glucose repression HO repression RME1 repression and sporulation
similar to uniprot|Q07786 Saccharomyces cerevisiae YDL246C SOR2 Protein of unknown function computational analysis of large-scale protein-protein interaction data suggests a possible role in fructose or mannose metabolism
similar to uniprot|P43561 Saccharomyces cerevisiae YFL041W
highly similar to uniprot|P25039 Saccharomyces cerevisiae YLR069C MEF1 mitochondrial elongation factor G-like protein
similar to uniprot|Q12247 Saccharomyces cerevisiae YLR068W FYV7 Protein of unknown function required for survival upon exposure to K1 killer toxin involved in processing the 35S rRNA primary transcript to generate the 20S and 27SA2 pre-rRNA transcripts
weakly similar to uniprot|P47068 Saccharomyces cerevisiae YJL020C BBC1 Protein possibly involved in assembly of actin patches interacts with an actin assembly factor Las17p and with the SH3 domains of Type I myosins Myo3p and Myo5p localized predominantly to cortical actin patches
similar to uniprot|P32522 Saccharomyces cerevisiae YLR067C PET309 Specific translational activator for the COX1 mRNA also influences stability of intron-containing COX1 primary transcripts located in the mitochondrial inner membrane
similar to uniprot|Q12133 Saccharomyces cerevisiae YLR066W SPC3 Subunit of signal peptidase complex (Spc1p Spc2p Spc3p Sec11p) which catalyzes cleavage of N-terminal signal sequences of proteins targeted to the secretory pathway homologous to mammalian SPC22/23
similar to gnl|GLV|CAGL0K12716g Candida glabrata CAGL0K12716g and weakly similar to YFL040W uniprot|P43562 Saccharomyces cerevisiae YFL040W Hypothetical ORF
some similarities with uniprot|P08640 Saccharomyces cerevisiae YIR019C MUC1 GPI-anchored cell surface glycoprotein required for diploid pseudohyphal formation and haploid invasive growth transcriptionally regulated by the MAPK pathway (via Ste12p and Tec1p) and the cAMP pathway (via Flo8p)
uniprot|Q2HWE7 Zygosaccharomyces rouxii ACT1 Actin
similar to uniprot|Q6Q5C1 Saccharomyces cerevisiae YLR065C Hypothetical ORF
highly similar to uniprot|P01123 Saccharomyces cerevisiae YFL038C YPT1 Ras-like small GTPase involved in the ER-to-Golgi step of the secretory pathway complex formation with the Rab escort protein Mrs6p is required for prenylation of Ypt1p by protein geranylgeranyltransferase type II (Bet2p-Bet4p)
similar to uniprot|Q12144 Saccharomyces cerevisiae YLR064W Hypothetical ORF
highly similar to uniprot|P02557 Saccharomyces cerevisiae YFL037W TUB2 Beta-tubulin associates with alpha-tubulin (Tub1p and Tub3p) to form tubulin dimer which polymerizes to form microtubules
similar to uniprot|P13433 Saccharomyces cerevisiae YFL036W
similar to uniprot|P43563 Saccharomyces cerevisiae YFL034C-B MOB2 Component of the RAM signaling network localizes and activates the Ace2p in the daughter cell nucleus to direct daughter cell-specific transcription of several genes involved in cell separation Mob1p-like protein
similar to uniprot|Q12291 Saccharomyces cerevisiae YLR063W Hypothetical ORF
highly similar to gnl|GLV|CAGL0F01683g Candida glabrata CAGL0F01683g and highly similar to YLR061W uniprot|P05749 Saccharomyces cerevisiae
similar to uniprot|P43564 Saccharomyces cerevisiae YFL034W Possible integral membrane protein that interacts with Rpp0p which is a component of the ribosomal stalk
highly similar to uniprot|P15624 Saccharomyces cerevisiae YLR060W
similar to uniprot|Q75BQ3 Ashbya gossypii ACR218W ACR218Wp and some similarites with YFL033C uniprot|P43565 Saccharomyces cerevisiae YFL033C RIM15 Glucose-repressible protein kinase involved in signal transduction during cell proliferation in response to nutrients specifically the establishment of stationary phase originally identified as a regulator of IME2
similar to uniprot|P54964 Saccharomyces cerevisiae YLR059C REX2 RNA exonuclease required for U4 snRNA maturation functions redundantly with Rnh70p in 5.8S rRNA maturation and with Rnh70p and Rex3p in processing of U5 snRNA and RNase P RNA member of RNase D family of exonucleases
some similarities with uniprot|P41546 Saccharomyces cerevisiae YFL031W HAC1 bZIP transcription factor (ATF/CREB1 homolog) that regulates the unfolded protein response via UPRE binding and membrane biogenesis ER stress-induced splicing pathway utilizing Ire1p Trl1p and Ada5p facilitates efficient Hac1p synthesis
similar to uniprot|P43567 Saccharomyces cerevisiae YFL030W
highly similar to uniprot|P37291 Saccharomyces cerevisiae YLR058C SHM2 serine hydroxymethyltransferase
similar to uniprot|Q7LGY1 Saccharomyces cerevisiae YLR057W Hypothetical ORF
similar to uniprot|P43568 Saccharomyces cerevisiae YFL029C CAK1 Cyclin-dependent kinase-activating kinase required for passage through the cell cycle phosphorylates and activates Cdc28p nucleotide-binding pocket differs significantly from those of most other protein kinases
highly similar to uniprot|P32353 Saccharomyces cerevisiae YLR056W ERG3 C-5 sterol desaturase catalyzes the introduction of a C-5(6) double bond into episterol a precursor in ergosterol biosynthesis mutants are viable but cannot grow on non-fermentable carbon sources
similar to uniprot|P43569 Saccharomyces cerevisiae YFL028C CAF16 Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex involved in controlling mRNA initiation elongation and degradation putative ABC ATPase interacts with Ssn2p Ssn3p and Ssn8p
similar to uniprot|P38915 Saccharomyces cerevisiae YLR055C SPT8 Subunit of the SAGA transcriptional regulatory complex but not present in SAGA-like complex SLIK/SALSA required for SAGA-mediated inhibition at some promoters
similar to uniprot|P43570 Saccharomyces cerevisiae YFL027C GYP8 GTPase-activating protein for yeast Rab family members Ypt1p is the preferred in vitro substrate but also acts on Sec4p Ypt31p and Ypt32p involved in the regulation of ER to Golgi vesicle transport
similar to uniprot|P06842 Saccharomyces cerevisiae YFL026W STE2 Receptor for alpha-factor pheromone seven transmembrane-domain protein that interacts with both pheromone and a heterotrimeric G protein to initiate the signaling response that leads to mating between haploid a and alpha cells
similar to uniprot|P43571 Saccharomyces cerevisiae YFL025C BST1 GPI inositol deacylase of the ER that negatively regulates COPII vesicle formation prevents production of vesicles with defective subunits required for proper discrimination between resident ER proteins and Golgi-bound cargo molecules
similar to uniprot|P43572 Saccharomyces cerevisiae YFL024C EPL1 Component of NuA4 which is an essential histone H4/H2A acetyltransferase complex homologous to Drosophila Enhancer of Polycomb
similar to uniprot|P43573 Saccharomyces cerevisiae YFL023W BUD27 Protein involved in bud-site selection nutrient signaling and gene expression controlled by the TOR kinase diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
some similarities with uniprot|Q12202 Saccharomyces cerevisiae YLR054C OSW2 Protein of unknown function proposed to be involved in the assembly of the spore wall
highly similar to uniprot|P15625 Saccharomyces cerevisiae YFL022C
similar to uniprot|Q12345 Saccharomyces cerevisiae YLR052W IES3 Subunit of the INO80 chromatin remodeling complex
similar to uniprot|Q12035 Saccharomyces cerevisiae YLR051C Protein required for cell viability
uniprot|P87016 Zygosaccharomyces rouxii SAT1 DNA-binding protein
highly similar to uniprot|P09624 Saccharomyces cerevisiae YFL018C LPD1 Dihydrolipoamide dehydrogenase the lipoamide dehydrogenase component (E3) of the pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase multi-enzyme complexes
highly similar to uniprot|P40204 Saccharomyces cerevisiae YFL017W-A SMX2 snRNP G protein (the homologue of the human Sm-G)
similar to uniprot|P43577 Saccharomyces cerevisiae YFL017C GNA1 Evolutionarily conserved glucosamine-6-phosphate acetyltransferase required for multiple cell cycle events including passage through START DNA synthesis and mitosis involved in UDP-N-acetylglucosamine synthesis forms GlcNAc6P from AcCoA
weakly similar to uniprot|Q12110 Saccharomyces cerevisiae YLR049C Hypothetical ORF
similar to uniprot|Q12155 Saccharomyces cerevisiae YLR050C Hypothetical ORF
similar to uniprot|Q752R6 Ashbya gossypii AFR507W AFR507Wp and some similarites with YFL016C uniprot|P35191 Saccharomyces cerevisiae YFL016C MDJ1 Protein involved in folding of mitochondrially synthesized proteins in the mitochondrial matrix localizes to the mitochondrial inner membrane member of the DnaJ family of molecular chaperones
weakly similar to uniprot|P38276 Saccharomyces cerevisiae YBR137W Hypothetical ORF
similar to uniprot|P22943 Saccharomyces cerevisiae YFL014W HSP12 Plasma membrane localized protein that protects membranes from desiccation induced by heat shock oxidative stress osmostress stationary phase entry glucose depletion oleate and alcohol regulated by the HOG and Ras-Pka pathways
weakly similar to uniprot|Q02732 Saccharomyces cerevisiae YPL018W CTF19 Outer kinetochore protein required for accurate mitotic chromosome segregation forms a complex with Mcm21p and Okp1p that binds to centromeres via the CBF3 complex
similar to uniprot|P43579 Saccharomyces cerevisiae YFL013C IES1 Subunit of the INO80 chromatin remodeling complex
weakly similar to uniprot|P43582 Saccharomyces cerevisiae YFL010C WWM1 WW domain containing protein interacting with Metacaspase (MCA1)
similar to uniprot|P07834 Saccharomyces cerevisiae YFL009W CDC4 F-box protein required for G1/S and G2/M transition associates with Skp1p and Cdc53p to form a complex SCFCdc4 which acts as ubiquitin-protein ligase directing ubiquitination of the phosphorylated CDK inhibitor Sic1p
similar to uniprot|P32908 Saccharomyces cerevisiae YFL008W SMC1 Subunit of the multiprotein cohesin complex essential protein involved in chromosome segregation and in double-strand DNA break repair SMC chromosomal ATPase family member binds DNA with a preference for DNA with secondary structure
similar to uniprot|P43583 Saccharomyces cerevisiae YFL007W BLM3 Protein involved in assembly of proteasomal core particles in the nucleus required for normal resistance to bleomycin may be involved in protection against oxidative damage
highly similar to uniprot|P07560 Saccharomyces cerevisiae YFL005W SEC4 Secretory vesicle-associated Rab GTPase essential for exocytosis associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane
similar to uniprot|P43585 Saccharomyces cerevisiae YFL004W VTC2 Phosphate metabolism transcription and similar to uniprot|Q02725 Saccharomyces cerevisiae YPL019C VTC3
similar to uniprot|Q02724 Saccharomyces cerevisiae YPL020C ULP1 Ubl (ubiquitin-like protein)-specific protease that cleaves Smt3p protein conjugates specifically required for cell cycle progression associates with nucleoporins and may interact with septin rings during telophase
similar to uniprot|P40965 Saccharomyces cerevisiae YFL003C MSH4 Protein involved in meiotic recombination required for normal levels of crossing over colocalizes with Zip2p to discrete foci on meiotic chromosomes has homology to bacterial MutS protein
similar to uniprot|P53686 Saccharomyces cerevisiae YPL015C HST2 Cytoplasmic member of the silencing information regulator 2 (Sir2) family of NAD()-dependent protein deacetylases modulates nucleolar (rDNA) and telomeric silencing possesses NAD()-dependent histone deacetylase activity in vitro
similar to uniprot|Q12532 Saccharomyces cerevisiae YPL009C Hypothetical ORF
highly similar to uniprot|P53600 Saccharomyces cerevisiae YPL010W RET3 Zeta subunit of the coatomer complex (COPI) which coats Golgi-derived transport vesicles involved in retrograde transport between Golgi and ER
similar to uniprot|Q12297 Saccharomyces cerevisiae YPL011C TAF3 TFIID subunit (47 kDa) involved in promoter binding and RNA polymerase II transcription initiation
similar to uniprot|Q7LH12 Saccharomyces cerevisiae YPL012W RRP12 Protein required for normal pre-rRNA Processing member of a group of seven genes whose expression is repressed during growth on glucose before and during the diauxic shift
mitochondrial 37S ribosomal protein MRPS16
highly similar to gnl|GLV|KLLA0F27247g Kluyveromyces lactis KLLA0F27247g and similar to YPL013C uniprot|Q02608 Saccharomyces cerevisiae YPL013C MRPS16 Mitochondrial ribosomal protein of the small subunit
weakly similar to uniprot|Q02606 Saccharomyces cerevisiae YPL014W Hypothetical ORF
similar to uniprot|P22516 Saccharomyces cerevisiae YPL008W
similar to uniprot|Q12308 Saccharomyces cerevisiae YPL007C TFC8 One of six subunits of RNA polymerase III transcription initiation factor complex (TFIIIC) part of TFIIIC TauB domain that binds BoxB promoter sites of tRNA and other genes linker between TauB and TauA domains human homolog is TFIIIC-90
similar to uniprot|Q12200 Saccharomyces cerevisiae YPL006W NCR1 Vacuolar membrane protein that transits through the biosynthetic vacuolar protein sorting pathway involved in sphingolipid metabolism glycoprotein homologous to human Niemann Pick C1 (NPC) protein
similar to uniprot|Q12089 Saccharomyces cerevisiae YPL005W AEP3 Peripheral mitochondrial inner membrane protein located on the matrix face of the membrane stabilizes the bicistronic AAP1-ATP6 mRNA encoding subunits 6 and 8 of the ATP synthase complex
highly similar to uniprot|Q12230 Saccharomyces cerevisiae YPL004C LSP1 Long chain base-responsive inhibitor of protein kinases Phk1p and Phk2p acts along with Pil1p to down-regulate heat stress resistance via regulation of the Pkc1p and Ypk1p pathways phosphorylated by Phk1p and Phk2p
highly similar to uniprot|P13298 Saccharomyces cerevisiae YML106W URA5 Fifth step in pyrimidine biosynthesis pathway Orotate phosphoribosyltransferase 1
similar to uniprot|Q12059 Saccharomyces cerevisiae YPL003W ULA1 Protein that acts together with Uba3p to activate Rub1p before its conjugation to proteins (neddylation) which may play a role in protein degradation
highly similar to uniprot|P25808 Saccharomyces cerevisiae YFL002C SPB4 involved in the maturation of 25S ribosomal RNA ATP-dependent RNA helicase
similar to uniprot|P31115 Saccharomyces cerevisiae YFL001W DEG1 Non-essential tRNA:pseudouridine synthase introduces pseudouridines at position 38 or 39 in tRNA important for maintenance of translation efficiency and normal cell growth localizes to both the nucleus and cytoplasm
highly similar to uniprot|Q12483 Saccharomyces cerevisiae YPL002C SNF8 Component of the ESCRT-II complex which is involved in ubiquitin-dependent sorting of proteins into the endosome appears to be functionally related to SNF7 involved in glucose derepression
similar to uniprot|Q12341 Saccharomyces cerevisiae YPL001W HAT1 Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex that uses the cofactor acetyl coenzyme A to acetylate free nuclear and cytoplasmic histone H4 involved in telomeric silencing and DNA double-strand break repair
similar to uniprot|P43586 Saccharomyces cerevisiae YFR001W LOC1 Nuclear protein involved in asymmetric localization of ASH1 mRNA binds double-stranded RNA in vitro
similar to uniprot|P43635 Saccharomyces cerevisiae YPR001W CIT3 Citrate synthase catalyzes the condensation of acetyl coenzyme A and oxaloacetate to form citrate mitochondrial isozyme involved in the TCA cycle
similar to uniprot|Q12428 Saccharomyces cerevisiae YPR002W PDH1 Mitochondrial protein that participates in respiration induced by diauxic shift homologous to E. coli PrpD may take part in the conversion of 2-methylcitrate to 2-methylisocitrate
similar to uniprot|P34077 Saccharomyces cerevisiae YFR002W NIC96 Component of the nuclear pore complex required for nuclear pore formation forms a subcomplex with Nsp1p Nup57p and Nup49p
weakly similar to uniprot|P43587 Saccharomyces cerevisiae YFR003C YPI1 Inhibitor of the type I protein phosphatase Glc7p which is involved in regulation of a variety of metabolic processes overproduction causes decreased cellular content of glycogen
highly similar to uniprot|P43588 Saccharomyces cerevisiae YFR004W RPN11 Metalloprotease subunit of the 19S regulatory particle of the 26S proteasome lid couples the deubiquitination and degradation of proteasome substrates
similar to uniprot|P43589 Saccharomyces cerevisiae YFR005C SAD1 Conserved zinc-finger domain protein involved in pre-mRNA splicing required for assembly of U4 snRNA into the U4/U6 particle
similar to uniprot|P43590 Saccharomyces cerevisiae YFR006W Hypothetical ORF
similar to uniprot|P38124 Saccharomyces cerevisiae YBR008C FLR1 Plasma membrane multidrug transporter member of the major facilitator superfamily involved in efflux of fluconazole diazaborine benomyl methotrexate and other drugs
similar to uniprot|P43592 Saccharomyces cerevisiae YFR008W FAR7 Protein involved in G1 cell cycle arrest in response to pheromone in a pathway different from the Far1p-dependent pathway interacts with Far3p Far8p Far9p Far10p and Far11p
similar to uniprot|Q12188 Saccharomyces cerevisiae YPR007C REC8 Meiosis-specific component of sister chromatid cohesion complex maintains cohesion between sister chromatids during meiosis I maintains cohesion between centromeres of sister chromatids until meiosis II homolog of S. pombe Rec8p
similar to uniprot|Q12031 Saccharomyces cerevisiae YPR006C ICL2 2-methylisocitrate lyase of the mitochondrial matrix functions in the methylcitrate cycle to catalyze the conversion of 2-methylisocitrate to succinate and pyruvate ICL2 transcription is repressed by glucose and induced by ethanol
similar to uniprot|P43591 Saccharomyces cerevisiae YFR007W Hypothetical ORF
similar to uniprot|Q12480 Saccharomyces cerevisiae YPR004C Hypothetical ORF
similar to uniprot|P53394 Saccharomyces cerevisiae YPR003C Hypothetical ORF
highly similar to uniprot|Q02895 Saccharomyces cerevisiae YPL088W Putative aryl alcohol dehydrogenase transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance
weakly similar to uniprot|Q12753 Saccharomyces cerevisiae YPR008W
similar to uniprot|P53107 Saccharomyces cerevisiae YGL164C YRB30 Competes with yeast RanBP1 (Yrb1p) for binding to the GTP-bound form of yeast Ran (Gsp1p) able to form trimeric complexes with RanGTP and some of the karyopherins inhibits RanGAP1(Rna1p)-mediated GTP hydrolysis on Ran.
highly similar to uniprot|P32863 Saccharomyces cerevisiae YGL163C RAD54 DNA-dependent ATPase stimulates strand exchange by modifying the topology of double-stranded DNA involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis member of the SWI/SNF family
some similarities with uniprot|Q12286 Saccharomyces cerevisiae YPR009W SUT2 Involved in sterol uptake homologous to SUT1
weakly similar to uniprot|P53108 Saccharomyces cerevisiae YGL161C YIP5 Protein that interacts with Rab GTPases computational analysis of large-scale protein-protein interaction data suggests a possible role in vesicle-mediated transport
similar to uniprot|P39988 Saccharomyces cerevisiae YEL029C
similar to uniprot|P47111 Saccharomyces cerevisiae YJR044C VPS55 Vacuolar Protein Sorting YJR044c
highly similar to uniprot|P12398 Saccharomyces cerevisiae YJR045C
similar to uniprot|P47112 Saccharomyces cerevisiae YJR046W TAH11 (DNA replication)
highly similar to uniprot|P39986 Saccharomyces cerevisiae YEL031W SPF1 Sensitivity to a killer toxin (SMK toxin) produced by Pichia Farinosa P-type ATPase
similar to uniprot|P24279 Saccharomyces cerevisiae YEL032W MCM3 Protein involved in DNA replication component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex
highly similar to uniprot|P19211 Saccharomyces cerevisiae ANB1 Translation initiation factor eIF-5A, and to YEL034W uniprot|P23301 Saccharomyces cerevisiae YEL034W HYP2 Translation initiation factor eIF-5A
similar to uniprot|P32629 Saccharomyces cerevisiae YEL036C ANP1 Mannan 8 Protein of the endoplasmic reticulum with a role in retention of glycosyltransferases in the Golgi also involved in osmotic sensitivity and resistance to aminonitrophenyl propanediol subunit of mannosyltransferase complex
similar to uniprot|P32628 Saccharomyces cerevisiae YEL037C RAD23
similar to uniprot|Q12068 Saccharomyces cerevisiae YOL151W and similar to uniprot|Q03049 Saccharomyces cerevisiae YDR541C
similar to uniprot|P32626 Saccharomyces cerevisiae YEL038W UTR4 Protein of unknown function found in both the cytoplasm and nucleus
highly similar to uniprot|P00044 Saccharomyces cerevisiae CYC1 Cytochrome c isoform 1 and to YEL039C uniprot|P00045 Saccharomyces cerevisiae CYC7 Cytochrome c isoform 2
similar to uniprot|P32623 Saccharomyces cerevisiae YEL040W UTR2 Putative glycosidase glycosylphosphatidylinositol (GPI)-anchored protein localized to the bud neck has a role in cell wall maintenance
similar to uniprot|P21373 Saccharomyces cerevisiae YJR049C UTR1 NAD kinase active as a hexamer enhances the activity of ferric reductase (Fre1p)
highly similar to uniprot|P32621 Saccharomyces cerevisiae YEL042W GDA1 Guanosine diphosphatase located in the Golgi involved in the transport of GDP-mannose into the Golgi lumen by converting GDP to GMP after mannose is transferred its substrate
similar to uniprot|P21374 Saccharomyces cerevisiae YJR050W ISY1 Component of the spliceosome complex involved in pre-mRNA splicing auxiliary splicing factor that may modulate Syf1p activity and help optimize splicing isy1 syf2 double mutation activates the spindle checkpoint causing cell cycle arrest
some similarities with uniprot|P38723 Saccharomyces cerevisiae YHL048W COS8
weakly similar to uniprot|P32618 Saccharomyces cerevisiae YEL043W member vGLC.2184
similar to uniprot|P32617 Saccharomyces cerevisiae YEL044W IES6 Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions
highly similar to uniprot|P37303 Saccharomyces cerevisiae YEL046C GLY1 Threonine aldolase catalyzes the cleavage of L-allo-threonine and L-threonine to glycine involved in glycine biosynthesis
similar to uniprot|P32614 Saccharomyces cerevisiae YEL047C Fumurate ReDuctase Soluble
similar to uniprot|P32613 Saccharomyces cerevisiae YEL048C Hypothetical ORF
weakly similar to uniprot|O00022 Saccharomyces cerevisiae YOR059C
weakly similar to uniprot|P48568 Saccharomyces cerevisiae YDL186W Hypothetical ORF
highly similar to uniprot|P23595 Saccharomyces cerevisiae YDL188C PPH22 Catalytic subunit of protein phosphatase 2A functionally redundant with Pph21p methylated at C terminus forms alternate complexes with several regulatory subunits involved in signal transduction and regulation of mitosis
highly similar to uniprot|Q12434 Saccharomyces cerevisiae YDL135C RDI1 Rho GDP dissociation inhibitor
some similarities with uniprot|Q870H2 Saccharomyces cerevisiae YDL189W RBS1 Protein of unknown function identified as a high copy suppressor of psk1 psk2 mutations that confer temperature-sensitivity for galactose utilization proposed to bind single-stranded nucleic acids via its R3H domain
similar to uniprot|Q06096 Saccharomyces cerevisiae YPR105C COG4 component of oligomeric Golgi complex
highly similar to uniprot|P39741 Saccharomyces cerevisiae YDL191W RPL35A and YDL136W RPL35B, proteins component of the large (60S) ribosomal subunit
highly similar to uniprot|P11076 Saccharomyces cerevisiae YDL192W ARF1 ADP-ribosylation factor GTPase of the Ras superfamily involved in regulation of coated formation vesicles in intracellular trafficking within the Golgi functionally interchangeable with Arf2p
similar to uniprot|Q12063 Saccharomyces cerevisiae YDL193W NUS1
similar to uniprot|P10870 Saccharomyces cerevisiae YDL194W SNF3 glucose sensor
similar to uniprot|P38968 Saccharomyces cerevisiae YDL195W SEC31 involved in protein transport from endoplasmic reticulum to Golgi Component (p150) of COPII coat of secretory pathway vesicles
similar to uniprot|Q05809 Saccharomyces cerevisiae YLR218C Hypothetical ORF
weakly similar to uniprot|Q12334 Saccharomyces cerevisiae YDL139C SCM3 Suppressor of chromosome missegregation
highly similar to uniprot|P53691 Saccharomyces cerevisiae YLR216C CPR6 Peptidyl-prolyl cis-trans isomerase (cyclophilin) catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues binds to Hsp82p and contributes to chaperone activity
highly similar to uniprot|P04050 Saccharomyces cerevisiae YDL140C
similar to uniprot|P48445 Saccharomyces cerevisiae YDL141W BPL1 Biotin:apoprotein ligase
similar to uniprot|Q07560 Saccharomyces cerevisiae YDL142C CRD1 Cardiolipin synthase produces cardiolipin which is an important constituent of mitochondrial membranes required for normal mitochondrial membrane potential and function
highly similar to uniprot|P39078 Saccharomyces cerevisiae YDL143W CCT4 Subunit of the cytosolic chaperonin Cct ring complex related to Tcp1p required for the assembly of actin and tubulins in vivo
similar to uniprot|Q05791 Saccharomyces cerevisiae YLR215C CDC123
similar to uniprot|Q07589 Saccharomyces cerevisiae YDL144C Hypothetical ORF
similar to uniprot|Q05790 Saccharomyces cerevisiae YLR213C
similar to uniprot|Q02933 Saccharomyces cerevisiae YPL123C RNY1 RNAse member of the T(2) family of endoribonucleases
similar to uniprot|Q08579 Saccharomyces cerevisiae YOR192C Hypothetical ORF
some similarities with uniprot|P29461 Saccharomyces cerevisiae YOR208W PTP2 Phosphotyrosine-specific protein phosphatase involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing dephosporylates Hog1p MAPK and regulates its localization localized to the nucleus
highly similar to uniprot|Q02932 Saccharomyces cerevisiae YPL125W KAP120 Karyopherin with a role in the assembly or export of 60S ribosomal subunits
highly similar to uniprot|P39683 Saccharomyces cerevisiae YOR209C NPT1 Nicotinate phosphoribosyltransferase
similar to Q02931 YPL126W uniprot|Q02931 Saccharomyces cerevisiae NAN1 U3 snoRNP protein component of the small (ribosomal) subunit (SSU) processosome containing U3
highly similar to uniprot|P22139 Saccharomyces cerevisiae YOR210W RPB10 RNA polymerase subunit ABC10-beta common to RNA polymerases I II and III
similar to uniprot|P32266 YOR211C Saccharomyces cerevisiae MGM1 Mitochondrial GTPase related to dynamin present in a complex containing Ugo1p and Fzo1p
similar to uniprot|P53551 Saccharomyces cerevisiae YPL127C HHO1 Histone H1 a linker histone required for nucleosome packaging at restricted sites suppresses DNA repair involving homologous recombination not required for telomeric silencing basal transcriptional repression or efficient sporulation
similar to uniprot|Q02457 YPL128C Saccharomyces cerevisiae TBF1 TTAGGG repeat binding factor
similar to uniprot|P18851 YOR212W Saccharomyces cerevisiae STE4 G protein beta subunit
similar to uniprot|Q99314 Saccharomyces cerevisiae YOR213C SAS5 Subunit of the SAS complex (Sas2p Sas4p Sas5p) which acetylates free histones and nucleosomes and regulates transcriptional silencing stimulates Sas2p HAT activity
highly similar to uniprot|P35189 Saccharomyces cerevisiae YPL129W TAF14 Subunit (30 kDa) of TFIID TFIIF and SWI/SNF complexes involved in RNA polymerase II transcription initiation and in chromatin modification contains a YEATS domain
similar to Q12032 YOR215C uniprot|Q12032 Saccharomyces cerevisiae Hypothetical ORF
similar to Q12234 YOR216C uniprot|Q12234 Saccharomyces cerevisiae RUD3 Golgi matrix protein that is involved in the structural organization of the cis-Golgi
similar to uniprot|P38630 Saccharomyces cerevisiae YOR217W RFC1 Subunit of heteropentameric Replication factor C (RF-C) which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon
similar to uniprot|P33894 Saccharomyces cerevisiae YOR219C STE13 Dipeptidyl aminopeptidase Golgi integral membrane protein that cleaves on the carboxyl side of repeating -X-Ala- sequences required for maturation of alpha factor transcription is induced by a-factor
highly similar to uniprot|P26321 Saccharomyces cerevisiae YPL131W RPL5 component of the large (60S) ribosomal subunit
similar to gnl|GLV|CAGL0J04158g Candida glabrata CAGL0J04158g and weakly similar to YOR220W uniprot|Q12044 Saccharomyces cerevisiae YOR220W Hypothetical ORF
similar to uniprot|P19516 YPL132W Saccharomyces cerevisiae COX11 Mitochondrial membrane protein required for assembly of active cytochrome c oxidase
similar to uniprot|P19541 Saccharomyces cerevisiae YPL133C RDS2 Regulator of drug sensitivity Transcriptional regulator
similar to uniprot|Q12283 Saccharomyces cerevisiae YOR221C MCT1 Predicted malonyl-CoA:ACP transferase putative component of a type-II mitochondrial fatty acid synthase that produces intermediates for phospholipid remodeling
similar to uniprot|Q03028 Saccharomyces cerevisiae YPL134C ODC1 Mitochondrial inner membrane transporter exports 2-oxoadipate and 2-oxoglutarate from the mitochondrial matrix to the cytosol for use in lysine and glutamate biosynthesis and in lysine catabolism
similar to uniprot|Q12015 Saccharomyces cerevisiae YOR223W Hypothetical ORF
highly similar to gnl|GLV|CAGL0J04070g Candida glabrata CAGL0J04070g and similar to YOR224C uniprot|P20436 Saccharomyces cerevisiae RPB8 RNA polymerase subunit ABC14.5 common to RNA polymerases I II and III
similar to uniprot|Q03020 Saccharomyces cerevisiae YPL135W ISU1 Conserved protein of the mitochondrial matrix
similar to uniprot|Q03016 Saccharomyces cerevisiae YPL137C Hypothetical ORF
similar to Q12106 YOR228C uniprot|Q12106 Saccharomyces cerevisiae Hypothetical ORF
similar to uniprot|Q03012 Saccharomyces cerevisiae YPL138C
similar to uniprot|Q12206 Saccharomyces cerevisiae YOR229W WTM2 WD repeat containing transcriptional modulator 2 Transcriptional modulator
similar to uniprot|P32491 Saccharomyces cerevisiae YPL140C MKK2 Mitogen-activated kinase kinase involved in protein kinase C signaling pathway that controls cell integrity upon activation by Bck1p phosphorylates downstream target Slt2p functionally redundant with Mkk1p
some similarities with uniprot|P38523 YOR232W Saccharomyces cerevisiae MGE1 Protein of the mitochondrial matrix involved in protein import into mitochondria
similar to Saccharomyces cerevisiae YPL141C and to YOR233W uniprot|Q01919 Saccharomyces cerevisiae YOR233W KIN4 Nonessential protein kinase with unknown cellular role
highly similar to uniprot|P05744 Saccharomyces cerevisiae YPL143W, RPL33A Ribosomal Protein of the Large subunit
similar to uniprot|Q6Q5F7 Saccharomyces cerevisiae YPL144W Hypothetical ORF
similar to uniprot|P07807 Saccharomyces cerevisiae YOR236W DFR1 Dihydrofolate reductase part of the dTTP biosynthetic pathway involved in folate metabolism possibly required for mitochondrial function
highly similar to gnl|GLV|KLLA0D07480g Kluyveromyces lactis KLLA0D07480g and similar to YPL145C uniprot|P35844 Saccharomyces cerevisiae YPL145C KES1 Member of the oxysterol binding protein family which includes seven yeast homologs involved in negative regulation of Sec14p-dependent Golgi complex secretory functions peripheral membrane protein that localizes to the Golgi complex
similar to uniprot|Q12080 Saccharomyces cerevisiae YPL146C NOP53 Nucleolar protein involved in biogenesis of the 60S subunit of the ribosome interacts with rRNA processing factors Cbf5p and Nop2p null mutant is viable but growth is severely impaired
similar to uniprot|Q08634 Saccharomyces cerevisiae YOR238W Hypothetical ORF
similar to uniprot|P41909 Saccharomyces cerevisiae YPL147W PXA1 Pxa1p and Pxa2p appear to be subunits of a peroxisomal ATP-binding cassette transporter necessary for transport of long-chain fatty acids into peroxisomes ABC family long-chain fatty acid transporter
similar to gnl|GLV|CAGL0M02365g Candida glabrata CAGL0M02365g and weakly similar to YPL148C uniprot|Q12036 Saccharomyces cerevisiae YPL148C PPT2 Phosphopantetheine:protein transferase (PPTase) activates mitochondrial acyl carrier protein (Acp1p) by phosphopantetheinylation
similar to uniprot|Q12380 Saccharomyces cerevisiae YPL149W ATG5 Conserved autophagy-related protein that undergoes conjugation with Atg12p and then associates with Atg16p to form a cytosolic complex essential for autophagosome formation
similar to uniprot|Q12152 Saccharomyces cerevisiae YPL150W Hypothetical ORF
similar to uniprot|Q08645 Saccharomyces cerevisiae YOR241W MET7 Folylpolyglutamate synthetase catalyzes extension of the glutamate chains of the folate coenzymes required for methionine synthesis and for maintenance of mitochondrial DNA present in both the cytoplasm and mitochondria
similar to uniprot|Q96US5 Saccharomyces cerevisiae YOR242C SSP2 Sporulation SPecific involved in sporulation
highly similar to uniprot|Q08647 Saccharomyces cerevisiae YOR243C PUS7 pseudouridylates U2 snRNA at position 35
similar to uniprot|Q12417 Saccharomyces cerevisiae YPL151C PRP46 Splicing factor that is found in the Cef1p subcomplex of the spliceosome
highly similar to uniprot|Q08649 Saccharomyces cerevisiae YOR244W ESA1 Histone acetyltransferase catalytic subunit of the native multisubunit complex (NuA4) that acetylates four conserved internal lysines of histone H4 N-terminal tail required for cell cycle progression
highly similar to uniprot|Q12461 Saccharomyces cerevisiae YPL152W
similar to uniprot|Q08650 Saccharomyces cerevisiae YOR245C DGA1 Diacylglycerol acyltransferase catalyzes the terminal step of triacylglycerol (TAG) formation acylates diacylglycerol using acyl-CoA as an acyl donor localized to lipid particles
similar to uniprot|P22216 Saccharomyces cerevisiae YPL153C RAD53 Protein kinase required for cell-cycle arrest in response to DNA damage activated by trans autophosphorylation when interacting with hyperphosphorylated Rad9p
highly similar to uniprot|P07267 Saccharomyces cerevisiae YPL154C PEP4 Vacuolar aspartyl protease (proteinase A) required for the posttranslational precursor maturation of vacuolar proteinases synthesized as a zymogen self-activates
similar to uniprot|P28743 Saccharomyces cerevisiae YPL155C KIP2 Kinesin-related motor protein involved in mitotic spindle positioning
similar to uniprot|Q12052 Saccharomyces cerevisiae YPL157W TGS1 TrimethylGuanosine Synthase
some similarities with uniprot|Q99299 Saccharomyces cerevisiae YPL158C Hypothetical ORF
similar to uniprot|Q99373 Saccharomyces cerevisiae YPL159C PET20 Protein required for respiratory growth and stability of the mitochondrial genome
highly similar to uniprot|P26637 Saccharomyces cerevisiae YPL160W CDC60 Cytosolic leucyl tRNA synthetase ligates leucine to the appropriate tRNA
similar to uniprot|Q08651 Saccharomyces cerevisiae YOR246C Protein with similarity to oxidoreductases
similar to uniprot|P39011 Saccharomyces cerevisiae YPL161C BEM4 Protein involved in establishment of cell polarity and bud emergence interacts with the Rho1p small GTP-binding protein and with the Rho-type GTPase Cdc42p
similar to uniprot|Q12042 Saccharomyces cerevisiae YPL162C Hypothetical ORF
weakly similar to uniprot|Q12254 Saccharomyces cerevisiae YPL163C
similar to uniprot|Q12083 Saccharomyces cerevisiae YPL164C MLH3 Protein involved in DNA mismatch repair forms a complex with Mlh1p to promote meiotic crossing-over mammalian homolog is implicated mammalian microsatellite instability
similar to uniprot|Q08683 Saccharomyces cerevisiae YOR249C APC5 Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors including mitotic cyclins during the metaphase/anaphase transition
similar to uniprot|Q08685 Saccharomyces cerevisiae YOR250C CLP1 cleavage/polyadenylation factor IA subunit interacts with Pcf11p in the 2-hybrid system cleavage/polyadenylation factor IA subunit
similar to uniprot|Q08686 Saccharomyces cerevisiae YOR251C catalyzes transfer of the sulfane atom of thiosulfate to cyanide to form sulfite and thiocyanate
similar to uniprot|Q12529 Saccharomyces cerevisiae YPL165C SET6
similar to gnl|GLV|KLLA0C09933g Kluyveromyces lactis KLLA0C09933g and weakly similar to uniprot|Q12092 Saccharomyces cerevisiae YPL166W Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
similar to uniprot|P14284 Saccharomyces cerevisiae YPL167C REV3 Subunit of DNA polymerase zeta which is involved in DNA repair required for mutagenesis induced by DNA damage
similar to uniprot|Q08687 Saccharomyces cerevisiae YOR252W RBF17 Hypothetical ORF
weakly similar to uniprot|Q12467 Saccharomyces cerevisiae YPL168W Hypothetical ORF
similar to uniprot|P53118 Saccharomyces cerevisiae YGL144C ROG1 Protein with putative serine active lipase domain
similar to uniprot|P33891 Saccharomyces cerevisiae YGL145W TIP20 transport protein that interacts with Sec20p required for protein transport from the endoplasmic reticulum to the golgi apparatus
similar to uniprot|Q12513 Saccharomyces cerevisiae YDL110C Hypothetical ORF
weakly similar to uniprot|P53117 Saccharomyces cerevisiae YGL146C Hypothetical ORF
highly similar to uniprot|Q12277 Saccharomyces cerevisiae YDL111C RRP42 Ribosomal RNA Processing Component of the exosome 3->5 exoribonuclease complex with Rrp4p Rrp41p Rrp43p and Dis3p (Rrp44p).
similar to uniprot|Q7LGS3 Saccharomyces cerevisiae YDL112W TRM3 2'-O-ribose methyltransferase catalyzes the ribose methylation of the guanosine nucleotide at position 18 of tRNAs
similar to uniprot|Q07528 Saccharomyces cerevisiae YDL113C ATG20 Protein required for transport of aminopeptidase I (Lap4p) through the cytoplasm-to-vacuole targeting pathway binds phosphatidylinositol-3-phosphate involved in localization of membranes to the preautophagosome potential Cdc28p substrate
similar to uniprot|Q07530 Saccharomyces cerevisiae YDL114W Hypothetical ORF
similar to uniprot|A2TBP4 Saccharomyces cerevisiae YDL115C IWR1 Protein of unknown function deletion causes hypersensitivity to the K1 killer toxin
highly similar to uniprot|P05738 Saccharomyces cerevisiae uniprot|P05738 Saccharomyces cerevisiae YGL147C RPL9A Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl9Bp and has similarity to E. coli L6 and rat L9 ribosomal proteins and to YNL067W uniprot|P51401 Saccharomyces cerevisiae YNL067W RPL9B Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl9Ap and has similarity to E. coli L6 and rat L9 ribosomal proteins
similar to uniprot|Q2XN15 Saccharomyces cerevisiae YPL030W Hypothetical ORF
highly similar to uniprot|P17157 Saccharomyces cerevisiae YPL031C PHO85 Cyclin-dependent kinase with ten cyclin partners involved in environmental stress response in phosphate-rich conditions Pho85p-Pho80p complex phosphorylates Pho4p which in turn represses PHO5
similar to uniprot|Q03787 Saccharomyces cerevisiae YDR249C Hypothetical ORF
similar to uniprot|Q03088 Saccharomyces cerevisiae YPL032C SVL3 Protein of unknown function mutant phenotype suggests a potential role in vacuolar function green fluorescent protein (GFP)-fusion protein localizes to the cell periphery cytoplasm bud and bud neck
similar to uniprot|Q02642 Saccharomyces cerevisiae YPL037C EGD1 Subunit beta1 of the nascent polypeptide-associated complex (NAC) involved in protein targeting associated with cytoplasmic ribosomes enhances DNA binding of the Gal4p activator homolog of human BTF3b
similar to uniprot|Q12041 Saccharomyces cerevisiae YDR253C MET32 Zinc-finger DNA-binding protein, involved in regulating expression of the methionine biosynthetic genes
some similarities with uniprot|Q03080 Saccharomyces cerevisiae YPL039W Hypothetical ORF
similar to uniprot|P48526 Saccharomyces cerevisiae YPL040C ISM1 Mitochondrial isoleucyl-tRNA synthetase null mutant is deficient in respiratory growth
similar to uniprot|P38227 Saccharomyces cerevisiae YBR043C QDR3 Multidrug transporter required for resistance to quinidine barban cisplatin and bleomycin member of the major facilitator superfamily of transporters conferring multiple drug resistance (MFS-MDR)
some similarities with uniprot|Q6LE92 Saccharomyces cerevisiae YPL041C Hypothetical ORF
similar to uniprot|P39073 Saccharomyces cerevisiae YPL042C SSN3 Component of RNA polymerase II holoenzyme involved in RNA pol II carboxy-terminal domain phosphorylation
similar to uniprot|P37838 Saccharomyces cerevisiae YPL043W NOP4 Nucleolar protein essential for processing and maturation of 27S pre-rRNA and large ribosomal subunit biogenesis contains four RNA recognition motifs (RRMs)
similar to uniprot|P38907 Saccharomyces cerevisiae YDR254W CHL4 Outer kinetochore protein required for chromosome stability interacts with kinetochore proteins Ctf19p Ctf3p and Iml3p exhibits a two-hybrid interaction with Mif2p association with CEN DNA requires Ctf19p
similar to uniprot|Q03308 Saccharomyces cerevisiae YPL045W VPS16 Vacuolar sorting protein
similar to uniprot|O13292 Saccharomyces cerevisiae YPL046C ELC1 Elongin C forms heterodimer with Ela1p that participates in transcription elongation expression dramatically upregulated during sporulation widely conserved among eukaryotes
similar to uniprot|Q12508 Saccharomyces cerevisiae YDR255C RMD5 Cytosolic protein required for sporulation also required for the ubiquitination of the gluconeogenetic enzyme fructose-1 6-bisphosphatase which is degraded rapidly after the switch from gluconeogenesis to glycolysis
highly similar to uniprot|Q03067 Saccharomyces cerevisiae YPL047W SGF11 11kDa subunit of the SAGA histone acetyltransferase complex involved in regulation of transcription of a subset of SAGA-regulated genes
highly similar to uniprot|P15202 Saccharomyces cerevisiae YDR256C CTA1 Catalase A breaks down hydrogen peroxide in the peroxisomal matrix formed by acyl-CoA oxidase (Pox1p) during fatty acid beta-oxidation
elongation factor 1 gamma domain-containing protein
similar to uniprot|P29547 Saccharomyces cerevisiae YPL048W CAM1 Translational cofactor elongation factor-1 gamma participates in the regulation of GTP-binding protein EF-1 alpha may play a redundant role in the regulation of protein synthesis or another GTP-dependent process
some similarities with uniprot|Q03063 Saccharomyces cerevisiae YPL049C DIG1 Regulatory protein of unknown function constitutively-expressed involved in the regulation of mating-specific genes and the invasive growth pathway required for MAP-kinase imposed repression inhibits pheromone-responsive transcription
highly similar to uniprot|P39107 Saccharomyces cerevisiae YPL050C MNN9 Subunit of Golgi mannosyltransferase complex also containing Anp1p Mnn10p Mnn11p and Hoc1p that mediates elongation of the polysaccharide mannan backbone forms a separate complex with Van1p that is also involved in backbone elongation
similar to uniprot|P11491 Saccharomyces cerevisiae YDR481C PHO8 Repressible alkaline phosphatase a glycoprotein localized to the vacuole regulated by levels of inorganic phosphate and by a system consisting of Pho4p Pho9p Pho80p Pho81p and Pho85p dephosphorylates phosphotyrosyl peptides
highly similar to uniprot|Q02804 Saccharomyces cerevisiae YPL051W ARL3 GTPase of the Ras superfamily required to recruit Arl1p to the Golgi; similar to ADP-ribosylation factor
similar to uniprot|Q03375 Saccharomyces cerevisiae YDR482C
similar to uniprot|Q02803 Saccharomyces cerevisiae YPL052W OAZ1 Regulator of ornithine decarboxylase (Spe1p) antizyme that binds to Spe1p to regulate ubiquitin-independent degradation ribosomal frameshifting during synthesis of Oaz1p and its ubiquitin-mediated degradation are both polyamine-regulated
similar to uniprot|P27809 Saccharomyces cerevisiae YDR483W KRE2 Alpha1 2-mannosyltransferase of the Golgi involved in protein mannosylation
similar to uniprot|P33313 Saccharomyces cerevisiae YBR155W CNS1 cyclophilin seven suppressor component of Hsp90p chaperone machinery
some similarities with uniprot|P38283 Saccharomyces cerevisiae YBR156C SLI15 Mitotic spindle protein involved in chromosome segregation.
some similarities with uniprot|Q06701 Saccharomyces cerevisiae YPL054W LEE1 Protein of unknown function
similar to uniprot|P38285 Saccharomyces cerevisiae YBR158W AMN1 Involved in daughter cell separation and Chromosome STability Chromosome STability
some similarities with uniprot|Q6Q5I8 Saccharomyces cerevisiae YPL055C LGE1 Protein of unknown function null mutant forms abnormally large cells
similar to uniprot|P38286 Saccharomyces cerevisiae YBR159W microsomal beta-keto-reductase
highly similar to uniprot|P00546 Saccharomyces cerevisiae YBR160W CDC28 Catalytic subunit of the main cell cycle cyclin-dependent kinase (CDK) alternately associates with G1 cyclins (CLNs) and G2/M cyclins (CLBs) which direct the CDK to specific substrates
similar to uniprot|P33300 Saccharomyces cerevisiae YPL057C SUR1 Probable catalytic subunit of a mannosylinositol phosphorylceramide
weakly similar to uniprot|P38288 Saccharomyces cerevisiae YBR162C TOS1 Target of SBF
highly similar to uniprot|Q02785 Saccharomyces cerevisiae YPL058C PDR12 Plasma membrane weak-acid-inducible ATP-binding cassette (ABC) transporter required for weak organic acid resistance strongly induced by sorbate and benzoate regulated by War1p mutants exhibit sorbate hypersensitivity
similar to uniprot|P38289 Saccharomyces cerevisiae YBR163W
similar to uniprot|Q02784 Saccharomyces cerevisiae YPL059W GRX5 Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase mitochondrial matrix protein involved in the synthesis/assembly of iron-sulfur centers monothiol glutaredoxin subfamily member along with Grx3p and Grx4p
highly similar to uniprot|P32528 Saccharomyces cerevisiae YBR208C DUR1 2 Urea amidolyase contains both urea carboxylase and allophanate hydrolase activities degrades urea to CO2 and NH3 expression sensitive to nitrogen catabolite repression and induced by allophanate an intermediate in allantoin degradation
similar to uniprot|P38310 Saccharomyces cerevisiae YBR207W FTH1 Putative high affinity iron transporter involved in transport of intravacuolar stores of iron forms complex with Fet5p expression is regulated by iron proposed to play indirect role in endocytosis
similar to uniprot|Q6B1B1 Saccharomyces cerevisiae YPL060W LPE10 Mitochondrial inner membrane magnesium transporter involved in maintenance of magnesium concentrations inside mitochondria indirectly affects splicing of group II introns functionally and structurally related to Mrs2p
highly similar to uniprot|P38130 Saccharomyces cerevisiae YBR205W KTR3 Putative alpha-1 2-mannosyltransferase involved in O- and N-linked protein glycosylation member of the KRE2/MNT1 mannosyltransferase family
similar to uniprot|P38139 Saccharomyces cerevisiae YBR204C Hypothetical ORF
weakly similar to uniprot|Q08905 Saccharomyces cerevisiae YOR381W
some similarities with uniprot|P38308 Saccharomyces cerevisiae YBR203W COS111 Protein required for wild-type resistance to the antifungal drug ciclopirox olamine not related to the COS family of subtelomerically-encoded proteins
similar to uniprot|Q02776 Saccharomyces cerevisiae YPL063W TIM50 Protein of the inner mitochondrial membrane required for import of mitochondrial matrix proteins
weakly similar to uniprot|Q02770 Saccharomyces cerevisiae YPL064C
weakly similar to uniprot|Q03656 Saccharomyces cerevisiae YMR216C
similar to uniprot|Q02767 Saccharomyces cerevisiae YPL065W VPS28 Component of the ESCRT-I complex which is involved in ubiquitin-dependent sorting of proteins into the endosome involved in transport of precursors for soluble vacuolar hydrolases from the late endosome to the vacuole
similar to uniprot|Q12194 Saccharomyces cerevisiae YPL066W Hypothetical ORF
highly similar to uniprot|P38132 Saccharomyces cerevisiae YBR202W CDC47 Component of the hexameric MCM complex which is important for priming origins of DNA replication in G1 and becomes an active ATP-dependent helicase that promotes DNA melting and elongation when activated by Cdc7p-Dbf4p in S-phase
similar to uniprot|P39946 Saccharomyces cerevisiae YOR269W PAC1 Protein involved in nuclear migration part of the dynein/dynactin pathway targets dynein to microtubule tips which is necessary for sliding of microtubules along bud cortex synthetic lethal with bni1 homolog of human LIS1
similar to uniprot|P32563 Saccharomyces cerevisiae YOR270C VPH1 Subunit of vacuolar-ATPase V0 domain one of two isoforms (Vph1p and Stv1p) Vph1p is located in V-ATPase complexes of the vacuole while Stv1p is located in V-ATPase complexes of the Golgi and endosomes
similar to uniprot|P07277 Saccharomyces cerevisiae YMR208W ERG12 Mevalonate kinase acts in the biosynthesis of isoprenoids and sterols including ergosterol from mevalonate
similar to uniprot|Q12029 Saccharomyces cerevisiae YOR271C Hypothetical ORF
highly similar to uniprot|Q12024 Saccharomyces cerevisiae YOR272W YTM1 microtubule-associated protein
similar to uniprot|Q03648 Saccharomyces cerevisiae YMR209C Hypothetical ORF
similar to uniprot|Q03652 Saccharomyces cerevisiae YMR211W
similar to uniprot|P07884 Saccharomyces cerevisiae YOR274W MOD5 Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase required for biosynthesis of the modified base isopentenyladenosine in mitochondrial and cytoplasmic tRNAs gene is nuclear and encodes two isozymic forms
similar to uniprot|Q12033 Saccharomyces cerevisiae YOR275C RIM20 Protein involved in proteolytic activation of Rim101p in response to alkaline pH member of the PalA/AIP1/Alix family interacts with the ESCRT-III subunits Snf7p suggesting a relationship between the response to pH and multivesicular body formation
similar to uniprot|Q03653 Saccharomyces cerevisiae YMR212C EFR3 Non-essential protein of unknown function exhibits synthetic lethal genetic interactions with PHO85 green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
similar to uniprot|Q03654 Saccharomyces cerevisiae YMR213W CEF1 Essential splicing factor associated with Prp19p and the spliceosome contains an N-terminal c-Myb DNA binding motif necessary for cell viability but not for Prp19p association evolutionarily conserved and homologous to S. pombe Cdc5p
similar to uniprot|P07285 YDR354W Saccharomyces cerevisiae TRP4 anthranilate phosphoribosyl transferase
similar to uniprot|Q756L3 Ashbya gossypii AER241W AER241Wp and weakly similar to uniprot|P32380 Saccharomyces cerevisiae YDR356W SPC110 Inner plaque spindle pole body (SPB) component
similar to uniprot|Q06333 YDR357C Saccharomyces cerevisiae Protein of unknown function
similar to uniprot|P38817 YHR108W Saccharomyces cerevisiae GGA2 Golgi-localized protein with homology to gamma-adaptin
similar to uniprot|Q06337 YDR359C Saccharomyces cerevisiae VID21 Component of the NuA4 histone acetyltransferase complex
similar to uniprot|Q06338 YDR361C Saccharomyces cerevisiae BCP1 Essential protein involved in nuclear export of Mss4p
weakly similar to uniprot|P38818 YHR109W Saccharomyces cerevisiae CTM1 Cytochrome c lysine methyltransferase
similar to uniprot|P38819 Saccharomyces cerevisiae YHR110W
similar to uniprot|P38820 YHR111W Saccharomyces cerevisiae UBA4 Protein that activates Urm1p before its conjugation to proteins (urmylation)
similar to uniprot|Q06339 YDR362C Saccharomyces cerevisiae TFC6 one of six subunits of RNA polymerase III transcription initiation factor complex (TFIIIC)
highly similar to uniprot|P38716 Saccharomyces cerevisiae YHR112C Hypothetical ORF
highly similar to uniprot|P38821 YHR113W Saccharomyces cerevisiae Hypothetical ORF
weakly similar to uniprot|Q06340 YDR363W Saccharomyces cerevisiae ESC2 Protein involved in mating-type locus silencing interacts with Sir2p
highly similar to uniprot|P04051 Saccharomyces cerevisiae YOR116C
weakly similar to uniprot|O94742 Saccharomyces cerevisiae YDR363W-A SEM1
highly similar to uniprot|P33297 Saccharomyces cerevisiae YOR117W RPT5 One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates recruited to the GAL1-10 promoter region upon induction of transcription
similar to uniprot|P40968 Saccharomyces cerevisiae YDR364C CDC40 Pre-mRNA splicing factor important for catalytic step II of pre-mRNA splicing and plays a role in cell cycle progression required for DNA synthesis during mitosis and meiosis has WD repeats
similar to uniprot|Q06344 YDR365C Saccharomyces cerevisiae ESF1 Nucleolar protein involved in pre-rRNA processing
similar to uniprot|Q12108 YOR118W Saccharomyces cerevisiae Hypothetical ORF
similar to uniprot|Q12196 YOR119C Saccharomyces cerevisiae RIO1 Essential protein that plays a role in cell cycle progression
similar to uniprot|Q06999 Saccharomyces cerevisiae YDR367W Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
uniprot|Q9HGX9 Zygosaccharomyces rouxii ZGCY2 Glycerol dehydrogenase
weakly similar to uniprot|P33301 Saccharomyces cerevisiae YDR369C XRS2 classified as an early recombination function required for DNA repair but dispensable for mitotic recombination (xrs2 is hyper-Rec during vegatative growth) required for double strand breaks meiotic recombination and spore viability DNA repair protein
similar to gnl|GLV|KLLA0E02222g Kluyveromyces lactis KLLA0E02222g and some similarites with YNL026W uniprot|P53969 Saccharomyces cerevisiae YNL026W SAM50 Essential component of the Sorting and Assembly Machinery (SAM complex) of the mitochondrial outer membrane the authentic non-tagged protein was localized to the mitochondria
similar to uniprot|Q06349 Saccharomyces cerevisiae YDR370C Hypothetical ORF
highly similar to uniprot|P07274 Saccharomyces cerevisiae YOR122C PFY1 Profilin actin- and phosphatidylinositol 4 5-bisphosphate-binding protein plays a role in cytoskeleton organization required for normal timing of actin polymerization in response to thermal stress localizes to plasma membrane and cytosol
similar to uniprot|P38439 Saccharomyces cerevisiae YOR123C LEO1 Component of the Paf1 complex which associates with RNA polymerase II and is involved in histone methylation
similar to uniprot|Q06350 Saccharomyces cerevisiae YDR371W CTS2 Sporulation-specific chitinase
highly similar to uniprot|Q06385 Saccharomyces cerevisiae YDR372C VPS74
similar to uniprot|P12630 Saccharomyces cerevisiae YIL015W BAR1 Aspartyl protease secreted into the periplasmic space of mating type a cells, cleaves and inactivates alpha factor allowing cells to recover from alpha-factor-induced cell cycle arrest and to YLR121C uniprot|Q12303 Saccharomyces cerevisiae YLR121C YPS3 Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor and to YLR120C uniprot|P32329 Saccharomyces cerevisiae YLR120C YPS1 Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor and to YDR144C uniprot|P53379 Saccharomyces cerevisiae YDR144C MKC7 GPI-anchored aspartyl protease (yapsin) involved in protein processing; shares functions with Yap3p and Kex2p and to YIR039C uniprot|P40583 Saccharomyces cerevisiae YIR039C YPS6 Putative GPI-anchored aspartic protease, member on vGLC.1466.
weakly similar to YYIL015W uniprot|P12630 Saccharomyces cerevisiae YIL015W BAR1 Aspartyl protease secreted into the periplasmic space of mating type a cells, cleaves and inactivates alpha factor allowing cells to recover from alpha-factor-induced cell cycle arrest and to YLR121C uniprot|Q12303 Saccharomyces cerevisiae YLR121C YPS3 Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor and to YLR120C uniprot|P32329 Saccharomyces cerevisiae YLR120C YPS1 Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor and to YDR144C uniprot|P53379 Saccharomyces cerevisiae YDR144C MKC7 GPI-anchored aspartyl protease (yapsin) involved in protein processing; shares functions with Yap3p and Kex2p and to YIR039C uniprot|P40583 Saccharomyces cerevisiae YIR039C YPS6 Putative GPI-anchored aspartic protease, member on vGLC.1466.
weakly similar to uniprot|P12630 Saccharomyces cerevisiae YIL015W BAR1 Aspartyl protease secreted into the periplasmic space of mating type a cells, cleaves and inactivates alpha factor allowing cells to recover from alpha-factor-induced cell cycle arrest and to YLR121C uniprot|Q12303 Saccharomyces cerevisiae YLR121C YPS3 Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor and to YLR120C uniprot|P32329 Saccharomyces cerevisiae YLR120C YPS1 Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor and to YDR144C uniprot|P53379 Saccharomyces cerevisiae YDR144C MKC7 GPI-anchored aspartyl protease (yapsin) involved in protein processing; shares functions with Yap3p and Kex2p and to YIR039C uniprot|P40583 Saccharomyces cerevisiae YIR039C YPS6 Putative GPI-anchored aspartic protease, member on vGLC.1466.
similar to uniprot|Q7LGV7 Saccharomyces cerevisiae YLR127C
similar to uniprot|Q12395 Saccharomyces cerevisiae YLR128W DCN1 Hypothetical ORF
some similarities with uniprot|Q03761 Saccharomyces cerevisiae YDR145W
similar to uniprot|Q12220 Saccharomyces cerevisiae YLR129W DIP2 Nucleolar protein specifically associated with the U3 snoRNA part of the large ribonucleoprotein complex known as the small subunit (SSU) processome required for 18S rRNA biogenesis part of the active pre- rRNA processing complex
similar to uniprot|P21192 Saccharomyces cerevisiae YLR131C ACE2 Transcription factor that activates expression of early G1-specific genes localizes to daughter cell nuclei after cytokinesis and delays G1 progression in daughters localization is regulated by phosphorylation potential Cdc28p substrate
weakly similar to uniprot|Q12208 Saccharomyces cerevisiae YLR132C Protein required for cell viability
similar to uniprot|P20485 Saccharomyces cerevisiae YLR133W CKI1 choline kinase
similar to uniprot|P19262 Saccharomyces cerevisiae YDR148C KGD2 Dihydrolipoyl transsuccinylase a component of the mitochondrial alpha-ketoglutarate dehydrogenase complex which catalyzes a step in the tricarboxylic acid (TCA) cycle the oxidative decarboxylation of alpha- ketoglutarate to succinyl-CoA
some similarities with uniprot|Q12098 Saccharomyces cerevisiae YLR135W SLX4 Subunit of a complex with Slx1p that hydrolyzes 5' branches from duplex DNA in response to stalled or converging replication forks function overlaps with that of Sgs1p-Top3p
weakly similar to uniprot|Q00402 Saccharomyces cerevisiae YDR150W NUM1 Protein required for nuclear migration localizes to the mother cell cortex and the bud tip may mediate interactions of dynein and cytoplasmic microtubules with the cell cortex
similar to uniprot|P47976 Saccharomyces cerevisiae YDR151C CTH1 Member of the CCCH zinc finger family and uniprot|P47977 Saccharomyces cerevisiae YLR136C TIS11 mRNA-binding protein expressed during iron starvation
similar to uniprot|P00812 Saccharomyces cerevisiae YPL111W CAR1 Arginase responsible for arginine degradation expression responds to both induction by arginine and nitrogen catabolite repression disruption enhances freeze tolerance
weakly similar to uniprot|Q6B2A9 Saccharomyces cerevisiae YPL112C PEX25 Peripheral peroxisomal membrane peroxin required for the regulation of peroxisome size and maintenance recruits GTPase Rho1p to peroxisomes induced by oleate interacts with homologous protein Pex27p
similar to uniprot|Q02961 Saccharomyces cerevisiae YPL113C Putative dehydrogenase
similar to uniprot|P32773 Saccharomyces cerevisiae YOR194C TOA1 Transcription factor IIA large chain
weakly similar to uniprot|Q08581 Saccharomyces cerevisiae YOR195W SLK19 Kinetochore-associated protein required for normal segregation of chromosomes in meiosis and mitosis component of the FEAR regulatory network which promotes Cdc14p release from the nucleolus during anaphase potential Cdc28p substrate
similar to uniprot|P32873 Saccharomyces cerevisiae YPL115C BEM3 Rho GTPase activating protein (RhoGAP) involved in control of the cytoskeleton organization targets the essential Rho-GTPase Cdc42p which controls establishment and maintenance of cell polarity including bud-site assembly
highly similar to uniprot|Q74ZH6 Ashbya gossypii AGR231C AGR231Cp and similar to YOR196C uniprot|P32875 Saccharomyces cerevisiae
similar to uniprot|Q02959 Saccharomyces cerevisiae YPL116W HOS3 Trichostatin A-insensitive homodimeric histone deacetylase (HDAC)
similar to uniprot|Q08601 Saccharomyces cerevisiae YOR197W MCA1 Putative cysteine protease similar to mammalian caspases
similar to uniprot|P38934 Saccharomyces cerevisiae YOR198C BFR1 Component of mRNP complexes associated with polyribosomes implicated in secretion and nuclear segregation multicopy suppressor of BFA (Brefeldin A) sensitivity
highly similar to uniprot|P15496 Saccharomyces cerevisiae YPL117C IDI1 Isopentenyl diphosphate:dimethylallyl diphosphate isomerase (IPP isomerase) catalyzes an essential activation step in the isoprenoid biosynthetic pathway required for viability
uniprot|Q9UVE2 Zygosaccharomyces rouxii Hypothetical protein similar to YOR201C uniprot|P25270 Saccharomyces cerevisiae YOR201C MRM1 Ribose methyltransferase that modifies a functionally critical conserved nucleotide in mitochondrial 21S rRNA
uniprot|Q9UVE1 Zygosaccharomyces rouxii HIS3 Imidazoleglycerol-phosphate dehydratase
similar to uniprot|Q02950 Saccharomyces cerevisiae YPL118W MRP51; homolog group vGLR.3476 derived from GLR. 3476
similar to uniprot|P06634 Saccharomyces cerevisiae YOR204W DED1 ATP-dependent DEAD (Asp-Glu-Ala-Asp)-box RNA helicase required for translation initiation of all yeast mRNAs mutations in human DEAD-box DBY are a frequent cause of male infertility
highly similar to uniprot|P21524 Saccharomyces cerevisiae YER070W RNR1 Ribonucleotide-diphosphate reductase (RNR) and to YIL066C uniprot|P21672 Saccharomyces cerevisiae YIL066C RNR3 Ribonucleotide- diphosphate reductase (RNR), large subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits
similar to uniprot|Q02948 Saccharomyces cerevisiae YPL120W VPS30 Protein required for sorting and delivery of soluble hydrolases to the vacuole
similar to uniprot|Q08622 Saccharomyces cerevisiae YOR205C FMP38 The authentic non-tagged protein was localized to the mitochondria
similar to uniprot|P39744 Saccharomyces cerevisiae YOR206W NOC2 Protein that forms a nucleolar complex with Mak21p that binds to 90S and 66S pre-ribosomes as well as a nuclear complex with Noc3p that binds to 66S pre- ribosomes both complexes mediate intranuclear transport of ribosomal precursors
similar to uniprot|P32489 Saccharomyces cerevisiae YPL121C MEI5 Meiosis specific protein involved in DMC1-dependent meiotic recombination forms heterodimer with Sae3p proposed to be an assembly factor for Dmc1p
highly similar to uniprot|P22276 Saccharomyces cerevisiae YOR207C RET1 Second-largest subunit of RNA polymerase III which is responsible for the transcription of tRNA and 5S RNA genes and other low molecular weight RNAs
highly similar to uniprot|P87331 Saccharomyces cerevisiae YPL122C
highly similar to uniprot|P53622 Saccharomyces cerevisiae YDL145C COP1 Alpha subunit of COPI vesicle coatomer complex which surrounds transport vesicles in the early secretory pathway
similar to uniprot|P53378 Saccharomyces cerevisiae YLR212C TUB4 Gamma-tubulin involved in nucleating microtubules from both the cytoplasmic and nuclear faces of the spindle pole body
similar to uniprot|Q12342 Saccharomyces cerevisiae YDL146W Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cell periphery cytoplasm bud and bud neck
similar to uniprot|Q05789 Saccharomyces cerevisiae YLR211C Hypothetical ORF
highly similar to uniprot|Q12250 Saccharomyces cerevisiae YDL147W RPN5 Essential, non-ATPase regulatory subunit of the 26S proteasome lid
similar to uniprot|Q99207 Saccharomyces cerevisiae YDL148C NOP14 Nucleolar protein forms a complex with Noc4p that mediates maturation and nuclear export of 40S ribosomal subunits also present in the small subunit processome complex which is required for processing of pre-18S rRNA
similar to uniprot|Q12142 Saccharomyces cerevisiae YDL149W ATG9 Transmembrane protein involved in formation of Cvt and autophagic vesicles cycles between the pre-autophagosomal structure and other cytosolic punctate structures not found in autophagosomes
similar to uniprot|P25441 Saccharomyces cerevisiae YDL150W RPC53 RNA polymerase III subunit C53
similar to uniprot|Q05842 Saccharomyces cerevisiae YDL153C SAS10 Component of the small (ribosomal) subunit (SSU) processosome required for pre-18S rRNa processing essential nucleolar protein that when overproduced disrupts silencing
similar to uniprot|Q12175 Saccharomyces cerevisiae YDL154W MSH5 Protein of the MutS family forms a dimer with Msh4p that facilitates crossovers between homologs during meiosis msh5-Y823H mutation confers tolerance to DNA alkylating agents homologs present in C. elegans and humans
similar to uniprot|P24870 Saccharomyces cerevisiae YDL155W CLB3 Involved in mitotic induction and perhaps in DNA replication and spindle assembly G(sub)2-specific B-type cyclin and uniprot|P24871 Saccharomyces cerevisiae YLR210W CLB4
similar to uniprot|Q12510 Saccharomyces cerevisiae YDL156W Hypothetical ORF
highly similar to gnl|GLV|CAGL0I03520g Candida glabrata CAGL0I03520g and similar to YDL157C uniprot|Q12082 Saccharomyces cerevisiae YDL157C Hypothetical ORF
similar to uniprot|P06784 Saccharomyces cerevisiae YDL159W STE7 Signal transducing MAP kinase kinase involved in pheromone response where it phosphorylates Fus3p and in the pseudohyphal/invasive growth pathway through phosphorylation of Kss1p phosphorylated by Ste11p degraded by ubiquitin pathway
highly similar to uniprot|Q75BS4 Ashbya gossypii ACR197W DHH1 ATP-dependent RNA helicase DHH1 and similar to YDL160C uniprot|P39517 Saccharomyces cerevisiae YDL160C DHH1 Cytoplasmic DExD/H-box helicase stimulates mRNA decapping coordinates distinct steps in mRNA function and decay interacts with both the decapping and deadenylase complexes may have a role in mRNA export and translation
similar to uniprot|Q05788 Saccharomyces cerevisiae YLR209C PNP1 purine nucleoside phosphorylase specifically metabolizes inosine and guanosine nucleosides
highly similar to uniprot|Q04491 Saccharomyces cerevisiae YLR208W SEC13 Component of both the Nup84 nuclear pore sub-complex and of the COPII complex (Sar1p Sec13p Sec16p Sec23p Sec24p Sec31p Sfb2p and Sfb3p) which is important for the formation of ER to Golgi transport vesicles
similar to uniprot|Q05787 Saccharomyces cerevisiae YLR207W HRD3 Resident protein of the ER membrane that plays a central role in ER-associated protein degradation (ERAD) forms HRD complex with Hrd1p and ERAD determinants that engages in lumen to cytosol communication and coordination of ERAD events
some similarities with uniprot|Q3E829 Saccharomyces cerevisiae YDL160C-A Identified by homology to Ashbya gossypii
some similarities with uniprot|Q12518 Saccharomyces cerevisiae YDL161W ENT1
similar to uniprot|P04819 Saccharomyces cerevisiae YDL164C CDC9 DNA ligase found in the nucleus and mitochondria an essential enzyme that joins Okazaki fragments during DNA replication also acts in nucleotide excision repair base excision repair and recombination
similar to uniprot|P32339 Saccharomyces cerevisiae YLR205C HMX1 ER localized, heme-binding peroxidase involved in the degradation of heme
similar to uniprot|P32335 Saccharomyces cerevisiae YLR203C MSS51 Protein required for the maturation and translation of COX1 mRNA involved in maturation of COX1 and COB mRNA
highly similar to uniprot|P06100 Saccharomyces cerevisiae YDL165W CDC36 Component of the CCR4-NOT complex which has multiple roles in regulating mRNA levels including regulation of transcription and destabilizing mRNAs by deadenylation basal transcription factor
similar to uniprot|Q12055 Saccharomyces cerevisiae YDL166C FAP7 Essential nuclear protein involved in the oxidative stress response
some similarities with uniprot|P32770 Saccharomyces cerevisiae YDL167C NRP1
highly similar to uniprot|P32771 Saccharomyces cerevisiae YDL168W SFA1 Long-chain alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)
similar to uniprot|Q05779 Saccharomyces cerevisiae YLR201C FMP53
highly similar to uniprot|P52553 Saccharomyces cerevisiae YLR200W YKE2 Yeast nuclear gene
weakly similar to uniprot|Q05778 Saccharomyces cerevisiae YLR199C Hypothetical ORF
highly similar to uniprot|Q12460 Saccharomyces cerevisiae YLR197W SIK1 Component of the small (ribosomal) subunit (SSU) processosome that contains U3 snoRNA
similar to uniprot|Q08919 Saccharomyces cerevisiae YPL176C
similar to uniprot|P32363 Saccharomyces cerevisiae YPL175W SPT14 UDP-GlcNAc-binding and catalytic subunit of the enzyme that mediates I)
weakly similar to uniprot|P33420 Saccharomyces cerevisiae YPL174C NIP100 Large subunit of the dynactin complex which is involved in partitioning the mitotic spindle between mother and daughter cells putative ortholog of mammalian p150(glued)
highly similar to uniprot|P06704 Saccharomyces cerevisiae YOR257W CDC31 Component of the spindle pole body (SPB) half-bridge required for SPB duplication in mitosis and meiosis II homolog of mammalian centrin interacts with Kar1p
mitochondrial 54S ribosomal protein YmL40
similar to uniprot|P36534 Saccharomyces cerevisiae YPL173W MRPL40 Mitochondrial ribosomal protein of the large subunit
similar to uniprot|Q08702 Saccharomyces cerevisiae YOR258W HNT3 Member of the third branch of the histidine triad (HIT) superfamily of nucleotide-binding proteins similar to Aprataxin a Hint related protein that is mutated in individuals with ataxia with oculomotor apraxia
highly similar to uniprot|P53549 Saccharomyces cerevisiae YOR259C RPT4 One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates required for spindle pole body duplication localized mainly to the nucleus throughout the cell cycle
similar to uniprot|P09032 Saccharomyces cerevisiae YOR260W GCD1 Gamma subunit of the translation initiation factor eIF2B the guanine-nucleotide exchange factor for eIF2 activity subsequently regulated by phosphorylated eIF2 first identified as a negative regulator of GCN4 expression
similar to uniprot|P21592 Saccharomyces cerevisiae YPL172C COX10 Heme A:farnesyltransferase catalyzes the first step in the conversion of protoheme to the heme A prosthetic group required for cytochrome c oxidase activity human ortholog is associated with mitochondrial disorders
highly similar to uniprot|Q75F44 Ashbya gossypii AAL116W RPN8 26S proteasome regulatory subunit RPN8 and similar to uniprot|Q08723 Saccharomyces cerevisiae YOR261C
highly similar to uniprot|Q08726 Saccharomyces cerevisiae YOR262W Protein required for cell viability
some similarities with uniprot|Q08729 Saccharomyces cerevisiae YOR264W
highly similar to uniprot|P48606 Saccharomyces cerevisiae YOR265W RBL2 Protein involved in microtubule morphogenesis required for protection from excess free beta-tubulin proposed to be involved the folding of beta-tubulin
similar to gnl|GLV|KLLA0C07557g Kluyveromyces lactis KLLA0C07557g and weakly similar to YOR266W uniprot|P38969 Saccharomyces cerevisiae YOR266W PNT1 Involved in targeting of proteins to the mitochondrial inner membrane Pentamidine resistance protein involved in pentamidine resistance protein
similar to gnl|GLV|CAGL0C02893g Candida glabrata CAGL0C02893g and some similarites with YOR267C uniprot|Q07224 Saccharomyces cerevisiae YOR267C HRK1 Protein kinase implicated in activation of the plasma membrane H()- ATPase Pma1p in response to glucose metabolism plays a role in ion homeostasis
similar to uniprot|Q03558 Saccharomyces cerevisiae YHR179W OYE2 Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) homologous to Oye3p with slight differences in ligand binding and catalytic properties may be involved in sterol metabolism
highly similar to uniprot|Q05027 Saccharomyces cerevisiae YMR236W TAF9
similar to uniprot|Q08754 Saccharomyces cerevisiae YOR299W BUD7 Protein involved in bud-site selection diploid mutants display an axial-like budding pattern
similar to uniprot|Q05031 Saccharomyces cerevisiae YMR238W DFG5 Mannosidase essential glycosylphosphatidylinositol (GPI)-anchored membrane protein required for cell wall biogenesis involved in filamentous growth homologous to Dcw1p
similar to uniprot|Q08760 Saccharomyces cerevisiae YOR301W RAX1 Protein involved in bud site selection during bipolar budding localization requires Rax2p
highly similar to uniprot|P08521 Saccharomyces cerevisiae YOR302W
similar to uniprot|P07258 Saccharomyces cerevisiae YOR303W CPA1 Small subunit of carbamoyl phosphate synthetase
highly similar to uniprot|Q08773 Saccharomyces cerevisiae YOR304W ISW2 Member of the imitation-switch (ISWI) class of ATP-dependent chromatin remodeling complexes ATPase component that with Itc1p forms a complex required for repression of a-specific genes INO1 and early meiotic genes during mitotic growth
similar to uniprot|Q02555 Saccharomyces cerevisiae YMR239C RNT1 RNAase III cleaves a stem-loop structure at the 3' end of U2 snRNA to ensure formation of the correct U2 3' end
similar to uniprot|Q02554 Saccharomyces cerevisiae YMR240C CUS1 Protein required for assembly of U2 snRNP into the spliceosome forms a complex with Hsh49p and Hsh155p
similar to uniprot|O14468 Saccharomyces cerevisiae YOR304C-A
similar to uniprot|Q08774 Saccharomyces cerevisiae YOR305W Hypothetical ORF
highly similar to uniprot|Q04013 Saccharomyces cerevisiae YMR241W YHM2 Yeast suppressor gene of HM mutant (abf2) DNA-binding protein mtDNA stabilizing protein mitochondrial inner membrane protein with low homology to RIM2
similar to uniprot|P22215 Saccharomyces cerevisiae YOR307C SLY41 multicopy suppressor of ypt1 deletion homolog of chloroplast phosphate transporter
weakly similar to uniprot|Q12420 Saccharomyces cerevisiae YOR308C SNU66 66kD U4/U6.U5 snRNP associated protein
similar to uniprot|Q12499 Saccharomyces cerevisiae YOR310C NOP58 Protein involved in pre-rRNA processing 18S rRNA synthesis and snoRNA synthesis component of the small subunit processome complex which is required for processing of pre-18S rRNA
similar to uniprot|Q12382 Saccharomyces cerevisiae YOR311C HSD1 Endoplasmic reticulum (ER)-resident membrane protein overproduction induces enlargement of ER-like membrane structures and suppresses a temperature-sensitive sly1 mutation
highly similar to uniprot|P47913 Saccharomyces cerevisiae YOR312C
similar to uniprot|P09937 Saccharomyces cerevisiae YOR313C SPS4 Protein whose expression is induced during sporulation not required for sporulation heterologous expression in E. coli induces the SOS response that senses DNA damage
similar to uniprot|P20107 Saccharomyces cerevisiae YMR243C ZRC1 and to uniprot|P32798 Saccharomyces cerevisiae YOR316C COT1
similar to uniprot|Q04018 Saccharomyces cerevisiae YMR244W Hypothetical ORF
similar to uniprot|P25619 Saccharomyces cerevisiae YCR021C HSP30 Hydrophobic plasma membrane localized stress-responsive protein that negatively regulates the H()-ATPase Pma1p induced by heat shock ethanol treatment weak organic acid glucose limitation and entry into stationary phase
similar to uniprot|Q3E846 Saccharomyces cerevisiae YMR244C-A Hypothetical ORF
similar to uniprot|P30624 Saccharomyces cerevisiae YOR317W FAA1 Long chain fatty acyl-CoA synthetase with a preference for C12:0-C16:0 fatty acids involved in the activation of imported fatty acids not required for growth on nonfermentable carbon sources essential for stationary phase and similar to YMR246W uniprot|P47912 Saccharomyces cerevisiae YMR246W FAA4 Long chain fatty acyl-CoA synthetase and similar to YIL009W uniprot|P39002 Saccharomyces cerevisiae YIL009W FAA3 Long chain fatty acyl-CoA synthetase, has a preference for C16 and C18 fatty acids; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
similar to uniprot|Q99181 Saccharomyces cerevisiae YOR319W
similar to uniprot|Q12096 Saccharomyces cerevisiae YOR320C GNT1 N-acetylglucosaminyltransferase capable of modification of N-linked glycans in the Golgi apparatus
similar to uniprot|Q04781 Saccharomyces cerevisiae YMR247C Hypothetical ORF
similar to uniprot|P21182 Saccharomyces cerevisiae YOL052C SPE2 S-adenosylmethionine decarboxylase
similar to uniprot|Q04792 Saccharomyces cerevisiae YMR250W GAD1 Glutamate decarboxylase converts glutamate into gamma-aminobutyric acid (GABA) during glutamate catabolism involved in response to oxidative stress
highly similar to uniprot|Q05827 Saccharomyces cerevisiae YMR251W-A
similar to uniprot|P38197 Saccharomyces cerevisiae YBL036C Single-domain racemase possibly non-specific due to the lack of the second domain which presumably determines specificity
similar to uniprot|P38065 Saccharomyces cerevisiae YBL037W APL3 clathrin Associated Protein complex Large subunit Large subunit of clathrin associated protein complex
highly similar to uniprot|P38251 Saccharomyces cerevisiae YBR087W RFC5 Subunit of heteropentameric Replication factor C (RF-C) which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon
mitochondrial 54S ribosomal protein YmL47
highly similar to uniprot|Q1ET04 Saccharomyces bayanus MRPL16 Mitochondrial ribosomal protein large subunit and highly similar to YBL038W uniprot|P38064 Saccharomyces cerevisiae YBL038W MRPL16 Mitochondrial ribosomal protein of the large subunit
similar to uniprot|P27614 Saccharomyces cerevisiae YJL172W CPS1 Vacuolar carboxypeptidase yscS expression is induced under low-nitrogen conditions
similar to uniprot|P38170 Saccharomyces cerevisiae YBL097W BRN1 Essential protein required for chromosome condensation likely to function as an intrinsic component of the condensation machinery may influence multiple aspects of chromosome transmission and dynamics
similar to uniprot|P38169 Saccharomyces cerevisiae YBL098W BNA4 Kynurenine 3-mono oxygenase required for biosynthesis of nicotinic acid from tryptophan via kynurenine pathway
similar to uniprot|P32795 Saccharomyces cerevisiae YPR024W YME1 Mitochondrial inner membrane protease of the AAA family responsible for degradation of unfolded or misfolded mitochondrial gene products mutation causes an elevated rate of mitochondrial turnover
similar to uniprot|P37366 Saccharomyces cerevisiae YPR025C CCL1 Cyclin associated with protein kinase Kin28p which is the TFIIH-associated carboxy-terminal domain (CTD) kinase involved in transcription initiation at RNA polymerase II promoters
highly similar to uniprot|P07251 Saccharomyces cerevisiae YBL099W ATP1 Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase which is a large evolutionarily conserved enzyme complex required for ATP synthesis
similar to uniprot|P48016 Saccharomyces cerevisiae YPR026W ATH1 Vacuolar acid trehalase required for trehalose utilization
similar to uniprot|Q12402 Saccharomyces cerevisiae YPR028W YOP1 Protein that regulates vesicular traffic in stressed cells either to facilitate membrane turnover or to decrease unnecessary secretion
similar to uniprot|Q12028 Saccharomyces cerevisiae YPR029C APL4 Gamma-adaptin large subunit of the clathrin-associated protein (AP) complex
weakly similar to uniprot|P38167 Saccharomyces cerevisiae YBL101C ECM21 Non-essential protein of unknown function promoter contains several Gcn4p binding elements
highly similar to uniprot|P38166 Saccharomyces cerevisiae YBL102W
some similarities with uniprot|P38165 Saccharomyces cerevisiae YBL103C RTG3 Basic helix-loop-helix-leucine zipper (bHLH/Zip) transcription factor that forms a complex with another bHLH/Zip protein Rtg1p to activate the retrograde (RTG) and TOR pathways
similar to uniprot|P38069 Saccharomyces cerevisiae YBR015C MNN2 Alpha-1 2-mannosyltransferase responsible for addition of the first alpha-1 2-linked mannose to form the branches on the mannan backbone of oligosaccharides localizes to an early Golgi compartment
similar to uniprot|Q12311 Saccharomyces cerevisiae YPR031W NTO1 Component of the histone acetyltransferase complex
similar to uniprot|P38164 Saccharomyces cerevisiae YBL104C Hypothetical ORF
some similarities with uniprot|P24583 Saccharomyces cerevisiae YBL105C PKC1 Protein Kinase C
similar to uniprot|Q12038 Saccharomyces cerevisiae YPR032W SRO7 Suppressor of rho3 yeast homolog of the Drosphila tumor suppressor lethal giant larvae or similar to YBL106C uniprot|P38163 Saccharomyces cerevisiae YBL106C SRO77 Suppressor of defect in the small GTPase Rho3p yeast homolog of the Drosphila tumor suppressor lethal giant larvae
similar to uniprot|P38162 Saccharomyces cerevisiae YBL107C Hypothetical ORF
similar to uniprot|P47125 Saccharomyces cerevisiae YJR078W BNA2 Tryptophan 2 3-dioxygenase required for biosynthesis of nicotinic acid from tryptophan via kynurenine pathway
highly similar to uniprot|P07263 Saccharomyces cerevisiae YPR033C HTS1 Cytoplasmic and mitochondrial histidine tRNA synthetase encoded by a single nuclear gene that specifies two messages efficient mitochondrial localization requires both a presequence and an amino-terminal sequence
similar to uniprot|P47127 Saccharomyces cerevisiae YJR080C FMP26 The authentic non-tagged protein was localized to the mitochondria
similar to uniprot|P36125 Saccharomyces cerevisiae YKR030W GMH1 Golgi membrane protein of unknown function interacts with Gea1p and Gea2p required for localization of Gea2p computational analysis suggests a possible role in either cell wall synthesis or protein-vacuolar targeting
similar to uniprot|P36126 Saccharomyces cerevisiae YKR031C SPO14 Phospholipase D catalyzes the hydrolysis of phosphatidylcholine producing choline and phosphatidic acid involved in Sec14p-independent secretion required for meiosis and spore formation differently regulated in secretion and meiosis
weakly similar to uniprot|P53309 Saccharomyces cerevisiae YGR241C YAP1802 Yeast Assembly Polypeptide, member of AP180 protein family, binds Pan1p and clathrin; member of clathrin assembly polypeptide AP180 family and weakly similar to uniprot|P38856 Saccharomyces cerevisiae YHR161C YAP1801 Yeast Assembly Polypeptide member of AP180 protein family binds Pan1p and clathrin clathrin assembly protein
similar to uniprot|P53311 Saccharomyces cerevisiae YGR243W FMP43
similar to uniprot|P41903 Saccharomyces cerevisiae YJR019C TES1 Thioesterase peroxisomal acyl-CoA thioesterase
weakly similar to uniprot|Q12192 Saccharomyces cerevisiae YOR279C RFM1 DNA-binding protein required for repression of middle sporulation genes specificity factor that directs the Hst1p histone deacetylase to some of the promoters regulated by Sum1p
highly similar to uniprot|P53312 Saccharomyces cerevisiae YGR244C LSC2 Beta subunit of succinyl-CoA ligase which is a mitochondrial enzyme of the TCA cycle that catalyzes the nucleotide-dependent conversion of succinyl-CoA to succinate
similar to uniprot|Q03768 Saccharomyces cerevisiae YDR152W GIR2 RWD domain containing protein of unknown function
highly similar to uniprot|Q6Q5U2 Saccharomyces cerevisiae YDR153C ENT5 Protein containing an N-terminal epsin-like domain involved in clathrin recruitment and traffic between the Golgi and endosomes associates with the clathrin adaptor Gga2p clathrin adaptor complex AP-1 and clathrin
highly similar to uniprot|P14832 Saccharomyces cerevisiae YDR155C CPR1 Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin) catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues binds the drug cyclosporin A
similar to gnl|GLV|CAGL0E01155g Candida glabrata CAGL0E01155g and weakly similar to YDR156W uniprot|P50106 Saccharomyces cerevisiae YDR156W RPA14 RNA polymerase I subunit A14
highly similar to uniprot|P13663 Saccharomyces cerevisiae YDR158W HOM2 Aspartic beta semi-aldehyde dehydrogenase catalyzes the second step in the common pathway for methionine and threonine biosynthesis expression regulated by Gcn4p and the general control of amino acid synthesis
similar to uniprot|Q12367 Saccharomyces cerevisiae YLR137W Hypothetical ORF
similar to uniprot|P46674 Saccharomyces cerevisiae YDR159W SAC3 Nuclear pore-associated protein forms a complex with Thp1p that is involved in transcription and in mRNA export from the nucleus
similar to uniprot|Q99271 Saccharomyces cerevisiae YLR138W NHA1 Na+/H+ antiporter
similar to uniprot|Q03770 Saccharomyces cerevisiae YDR160W SSY1 Component of the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p) which senses external amino acid concentration and transmits intracellular signals that result in regulation of expression of amino acid permease genes
similar to uniprot|Q03771 Saccharomyces cerevisiae YDR161W interacts with PP2C
similar to uniprot|Q12163 Saccharomyces cerevisiae YDR162C NBP2 Protein involved in the HOG (high osmolarity glycerol) pathway negatively regulates Hog1p by recruitment of phosphatase Ptc1p the Pbs2p-Hog1p complex found in the nucleus and cytoplasm contains an SH3 domain that binds Pbs2p
similar to uniprot|Q03772 Saccharomyces cerevisiae YDR163W
similar to uniprot|P42900 Saccharomyces cerevisiae YLR139C SLS1 Mitochondrial membrane protein required for assembly of respiratory-chain enzyme complexes III and IV coordinates expression of mitochondrially-encoded genes may facilitate delivery of mRNA to membrane-bound translation machinery
weakly similar to uniprot|Q02983 Saccharomyces cerevisiae YLR141W RRN5 Transcription factor member of UAF (upstream activation factor) family along with Rrn9p and Rrn10p involved in transcription of rDNA by RNA polymerase I
similar to uniprot|P09368 Saccharomyces cerevisiae YLR142W PUT1 proline oxidase
similar to uniprot|Q07261 Saccharomyces cerevisiae YLR143W Hypothetical ORF
similar to uniprot|P30619 Saccharomyces cerevisiae YDR164C SEC1 Sm-like protein involved in docking and fusion of exocytic vesicles through binding to assembled SNARE complexes at the membrane localization to sites of secretion (bud neck and bud tip) is dependent on SNARE function
similar to uniprot|Q07268 Saccharomyces cerevisiae YLR144C ACF2 Intracellular beta-1 3-endoglucanase expression is induced during sporulation may have a role in cortical actin cytoskeleton assembly
similar to gnl|GLV|KLLA0D17072g Kluyveromyces lactis KLLA0D17072g and weakly similar to YLR145W uniprot|Q12530 Saccharomyces cerevisiae YLR145W RMP1 Protein required for cell viability component of RNase MRP which is involved in RNA processing in mitochondria
similar to uniprot|Q12455 Saccharomyces cerevisiae YLR146C SPE4 Spermine Synthase
similar to uniprot|Q03774 Saccharomyces cerevisiae YDR165W TRM82 Subunit of a tRNA methyltransferase complex composed of Trm8p and Trm82p that catalyzes 7-methylguanosine modification of tRNA
similar to uniprot|P89102 Saccharomyces cerevisiae YDR166C SEC5 Essential 107kDa subunit of the exocyst complex (Sec3p Sec5p Sec6p Sec8p Sec10p Sec15p Exo70p and Exo84p) which has the essential function of mediating polarized targeting of secretory vesicles to active sites of exocytosis
highly similar to uniprot|P43321 Saccharomyces cerevisiae YLR147C SMD3 involved in snRNP biogenesis and pre-mRNA splicing encodes a core snRNP protein
similar to uniprot|P27801 Saccharomyces cerevisiae YLR148W PEP3 Vacuolar peripheral membrane protein that promotes vesicular docking/fusion reactions in conjunction with SNARE proteins required for vacuolar biogenesis forms complex with Pep5p that mediates protein transport to the vacuole
similar to uniprot|Q12030 Saccharomyces cerevisiae YDR167W TAF10 Subunit (145 kDa) of TFIID and SAGA complexes involved in RNA polymerase II transcription initiation and in chromatin modification
similar to uniprot|P06101 Saccharomyces cerevisiae YDR168W CDC37 Essential Hsp90p co-chaperone necessary for passage through the START phase of the cell cycle
similar to uniprot|Q99296 Saccharomyces cerevisiae YLR149C Hypothetical ORF
similar to uniprot|Q12427 Saccharomyces cerevisiae YDR169C STB3 Protein
similar to uniprot|P39015 Saccharomyces cerevisiae YLR150W STM1 Protein that binds quadruplex nucleic acids multicopy suppressor of tom1 and pop2 mutations acts with Cdc13p to maintain telomere structure
similar to uniprot|Q12524 Saccharomyces cerevisiae YLR151C PCD1 Peroxisomal nudix pyrophosphatase with specificity for coenzyme A and CoA derivatives may function to remove potentially toxic oxidized CoA disulfide from peroxisomes to maintain the capacity for beta-oxidation of fatty acids
similar to uniprot|P54072 Saccharomyces cerevisiae YLR152C Hypothetical ORF
highly similar to uniprot|P52910 Saccharomyces cerevisiae YLR153C ACS2 Acetyl-coA synthetase isoform required for growth on glucose expressed under anaerobic conditions
similar to uniprot|P11075 Saccharomyces cerevisiae YDR170C SEC7 Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors involved in proliferation of the Golgi intra-Golgi transport and ER-to-Golgi transport found in the cytoplasm and on Golgi-associated coated vesicles
some similarities with uniprot|Q12329 Saccharomyces cerevisiae YDR171W HSP42 Small cytosolic stress-induced chaperone that forms barrel-shaped oligomers and suppresses the aggregation of non-native proteins oligomer dissociation is not required for function involved in cytoskeleton reorganization after heat shock
uniprot|Q9HGI4 Zygosaccharomyces rouxii SUP35 Eukaryotic peptide chain release factor GTP-binding subunit
similar to uniprot|P07250 Saccharomyces cerevisiae YDR173C ARG82 Protein involved in regulation of arginine-responsive and Mcm1p-dependent genes has a dual-specificity inositol polyphosphate kinase activity required for regulation of phosphate- and nitrogen- responsive genes
similar to uniprot|Q08913 Saccharomyces cerevisiae YOR390W Hypothetical ORF
highly similar to uniprot|P02365 Saccharomyces cerevisiae YPL090C RPS6A and to uniprot|P02365 Saccharomyces cerevisiae YBR181C RPS6B Proteins component of the small (40S) ribosomal subunit
highly similar to uniprot|P41921 Saccharomyces cerevisiae YPL091W GLR1 Cytosolic and mitochondrial glutathione oxidoreductase converts oxidized glutathione to reduced glutathione
similar to uniprot|Q2VQ77 Saccharomyces cerevisiae YPL092W SSU1
similar to uniprot|P38125 Saccharomyces cerevisiae YBR180W DTR1 Multidrug resistance dityrosine transporter of the major facilitator superfamily essential for spore wall synthesis facilitates the translocation of bisformyl dityrosine through the prospore membrane
highly similar to uniprot|Q02892 Saccharomyces cerevisiae YPL093W NOG1 Putative GTPase that associates with free 60S ribosomal subunits in the nucleolus and is required for 60S ribosomal subunit biogenesis member of the ODN family of nucleolar G-proteins
similar to uniprot|P21825 Saccharomyces cerevisiae YPL094C
similar to uniprot|P38297 Saccharomyces cerevisiae YBR179C FZO1 Mitochondrial integral membrane protein involved in mitochondrial fusion and maintenance of the mitochondrial genome contains N-terminal GTPase domain
similar to uniprot|P38295 Saccharomyces cerevisiae YBR177C EHT1 Possible serine hydrolase may be involved in lipid metabolism null mutant slightly temperature sensitive at 37C and similar to YPL095c uniprot|Q02891 Saccharomyces cerevisiae YPL095C Hypothetical ORF and weakly similar to YMR210w uniprot|Q03649 Saccharomyces cerevisiae YMR210W Hypothetical ORF
similar to uniprot|Q02890 Saccharomyces cerevisiae YPL096W PNG1 de-N-glycosylation enzyme peptide:N-glycanase
similar to uniprot|P48527 Saccharomyces cerevisiae YPL097W
similar to uniprot|Q02889 Saccharomyces cerevisiae YPL098C Hypothetical ORF
similar to gnl|GLV|KLLA0E24332g Kluyveromyces lactis KLLA0E24332g and some similarities with YPL099C uniprot|Q02888 Saccharomyces cerevisiae YPL099C FMP14 The authentic non-tagged protein was localized to the mitochondria
similar to uniprot|Q02887 Saccharomyces cerevisiae YPL100W ATG21 Phosphatidylinositol 3 5-bisphosphate-binding protein required for maturation of pro-aminopeptidase I predicted to fold as a seven-bladed beta-propeller displays punctate cytoplasmic localization
similar to uniprot|Q02884 Saccharomyces cerevisiae YPL101W ELP4 Elongator protein part of the HAP subcomplex of Elongator which is a six-subunit component of the RNA polymerase II holoenzyme required for Elongator structural integrity and histone acetyltransferase activity
similar to uniprot|Q02883 Saccharomyces cerevisiae YPL103C
similar to uniprot|P38122 Saccharomyces cerevisiae YBR176W ECM31 Ketopantoate hydroxymethyltransferase required for pantothenic acid biosynthesis converts 2-oxoisovalerate into 2-dehydropantoate
similar to uniprot|P15179 Saccharomyces cerevisiae YPL104W Mitochondrial aspartyl-tRNA synthetase, required for acylation of aspartyl-tRNA; yeast and bacterial aspartyl-, asparaginyl-, and lysyl-tRNA synthetases contain regions with high sequence similarity, suggesting a common ancestral gene
highly similar to uniprot|P38123 Saccharomyces cerevisiae YBR175W SWD3 Subunit of the COMPASS complex which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres
highly similar to uniprot|P38293 Saccharomyces cerevisiae YBR173C UMP1 Short-lived chaperone required for correct maturation of the 20S proteasome degraded by proteasome upon completion of its assembly involved in ubiquitin-mediated proteolysis mutant defective in degradation of short-lived proteins
weakly similar to uniprot|P32909 Saccharomyces cerevisiae YBR172C SMY2 partial suppressor of myo2-66 Kinesin-related protein suppressing myosin defects (MYO2) and to uniprot|Q02875 YPL105c
highly similar to uniprot|P33754 Saccharomyces cerevisiae YBR171W SEC66 Non-essential subunit of Sec63 complex (Sec63p Sec62p Sec66p and Sec72p) with Sec61 complex Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER
similar to uniprot|P33755 Saccharomyces cerevisiae YBR170C NPL4 Endoplasmic reticulum and nuclear membrane protein forms a complex with Cdc48p and Ufd1p that recognizes ubiquitinated proteins in the endoplasmic reticulum and delivers them to the proteasome for degradation
similar to uniprot|P40152 Saccharomyces cerevisiae YNL217W Hypothetical ORF
similar to uniprot|Q07688 Saccharomyces cerevisiae YDL235C YPD1 Phosphorelay intermediate protein phosphorylated by the plasma membrane sensor Sln1p in response to osmotic stress and then in turn phosphorylates the response regulators Ssk1p in the cytosol and Skn7p in the nucleus
similar to uniprot|P40151 Saccharomyces cerevisiae YNL218W MGS1 Protein with DNA-dependent ATPase and ssDNA annealing activities involved in maintenance of genome interacts functionally with DNA polymerase delta homolog of human Werner helicase interacting protein (WHIP)
similar to uniprot|P19881 Saccharomyces cerevisiae YDL236W PHO13 Alkaline phosphatase specific for p-nitrophenyl phosphate involved in dephosphorylation of histone II-A and casein
similar to uniprot|P53868 Saccharomyces cerevisiae YNL219C ALG9 catalyzes the transfer of mannose from Dol-P-Man to lipid-linked oligosaccharides mannosyltransferase
highly similar to uniprot|P80210 Saccharomyces cerevisiae YNL220W ADE12 Adenylosuccinate synthase catalyzes the first committed step in the 'de novo' biosynthesis of adenosine
similar to uniprot|P41812 Saccharomyces cerevisiae YNL221C POP1 Subunit of both RNase MRP which cleaves pre-rRNA and nuclear RNase P which cleaves tRNA precursors to generate mature 5' ends binds to the RPR1 RNA subunit in Rnase P
similar to uniprot|Q6B312 Saccharomyces cerevisiae YDL237W Hypothetical ORF
similar to uniprot|Q07729 Saccharomyces cerevisiae YDL238C GUD1 Guanine deaminase a catabolic enzyme of the guanine salvage pathway producing xanthine and ammonia from guanine activity is low in exponentially-growing cultures but expression is increased in post-diauxic and stationary-phase cultures
highly similar to uniprot|P53538 Saccharomyces cerevisiae YNL222W SSU72 Transcription/RNA-processing factor that associates with TFIIB and cleavage/polyadenylation factor Pta1p exhibits intrinsic phosphatase activity affects start site selection in vivo Nuclear zinc-finger motif containing protein.
similar to uniprot|P53867 Saccharomyces cerevisiae YNL223W ATG4 Cysteine protease required for autophagy cleaves Atg8p to a form required for autophagosome and Cvt vesicle generation mediates attachment of autophagosomes to microtubules through interactions with Tub1p and Tub2p
weakly similar to uniprot|P53866 Saccharomyces cerevisiae YNL224C Hypothetical ORF
weakly similar to uniprot|Q07732 Saccharomyces cerevisiae YDL239C ADY3 Protein required for spore wall formation thought to mediate assembly of a Don1p-containing structure at the leading edge of the prospore membrane via interaction with spindle pole body components potentially phosphorylated by Cdc28p
similar to uniprot|P53863 Saccharomyces cerevisiae YNL227C JJJ1 Protein that may function as a cochaperone as suggested by the presence of a DnaJ-like domain
similar to uniprot|P23202 Saccharomyces cerevisiae YNL229C URE2 Nitrogen catabolite repression regulator that acts by inhibition of GLN3 transcription in good nitrogen source altered form of Ure2p creates [URE3] prion
similar to uniprot|P53861 Saccharomyces cerevisiae YNL230C ELA1 Elongin A F-box protein that forms a heterodimer with Elc1p and participates in transcription elongation
highly similar to uniprot|P53860 Saccharomyces cerevisiae YNL231C PDR16 Phosphatidylinositol transfer protein (PITP) controlled by the multiple drug resistance regulator Pdr1p localizes to lipid particles and microsomes controls levels of various lipids may regulate lipid synthesis homologous to Pdr17p
similar to uniprot|P53859 Saccharomyces cerevisiae YNL232W CSL4 Subunit of the exosome which is an essential complex present in both nucleus and cytoplasm that mediates RNA processing and degradation
some similarities with uniprot|P53858 Saccharomyces cerevisiae YNL233W BNI4 Targeting subunit for Glc7p protein phosphatase localized to the bud neck required for localization of chitin synthase III to the bud neck via interaction with the chitin synthase III regulatory subunit Skt5p
similar to uniprot|Q75E71 Ashbya gossypii ABL201W ABL201Wp and weakly similar to YNL234W uniprot|P53857 Saccharomyces cerevisiae YNL234W Similar to globins and has a functional heme-binding domain involved in glucose signaling or metabolism regulated by Rgt1p
similar to uniprot|P32259 YNL236W Saccharomyces cerevisiae SIN4 involved in positive and negative regulation of transcription
similar to uniprot|P53584 Saccharomyces cerevisiae YNL237W
similar to uniprot|P13134 YNL238W Saccharomyces cerevisiae KEX2 Subtilisin-like protease (proprotein convertase)
highly similar to gnl|GLV|CAGL0J07568g Candida glabrata CAGL0J07568g and similar to YNL239W uniprot|Q01532 Saccharomyces cerevisiae YNL239W LAP3 Aminopeptidase of cysteine protease family has a DNA binding activity and acts as bleomycin hydrolase in vitro transcription is regulated by galactose via Gal4p
similar to uniprot|P23503 YNL240C Saccharomyces cerevisiae NAR1 Nuclear architecture related protein component of the cytosolic iron-sulfur (FeS) protein assembly machinery
highly similar to uniprot|P11412 YNL241C Saccharomyces cerevisiae ZWF1 Glucose-6-phosphate dehydrogenase
similar to uniprot|P35688 Saccharomyces cerevisiae YDL240W LRG1 Putative GTPase-activating protein (GAP) involved in the Pkc1p-mediated signaling pathway that controls cell wall integrity appears to specifically regulate 1 3-beta-glucan synthesis
similar to uniprot|P53855 YNL242W Saccharomyces cerevisiae ATG2 Peripheral membrane protein required for the formation of cytosolic sequestering vesicles involved in vacuolar import through both the Cvt pathway and autophagy
weakly similar to uniprot|P21691 Saccharomyces cerevisiae YKR101W SIR1 Protein involved in repression of transcription at the silent mating-type loci HML and HMR recruitment to silent chromatin requires interactions with Orc1p and with Sir4p through a common Sir1p domain binds to centromeric chromatin
similar to uniprot|P25379 Saccharomyces cerevisiae YCL064C CHA1 catabolism of hydroxy amino acids catabolic serine (threonine) dehydratase
similar to uniprot|Q6B2C0 Saccharomyces cerevisiae YCR039C MATALPHA2 Homeobox-domain containing protein which in haploid cells acts with Mcm1p to repress a-specific genes in diploid cells Alpha2p acts together with A1p to repress transcription of haploid-specific genes
similar to uniprot|P01365 Saccharomyces cerevisiae YCR040W MATALPHA1 Transcriptional co-activator involved in regulation of mating-type-specific gene expression targets the transcription factor Mcm1p to the promoters of alpha-specific genes one of two genes encoded by the alpha mating type cassette
some similarities with uniprot|P33338 Saccharomyces cerevisiae YNL243W SLA2 Transmembrane actin-binding protein involved in membrane cytoskeleton assembly and cell polarization adaptor protein that links actin to clathrin and endocytosis present in the actin cortical patch of the emerging bud tip dimer in vivo
highly similar to uniprot|P32911 Saccharomyces cerevisiae YNL244C SUI1 translation initiation factor eIF1
similar to uniprot|P53854 Saccharomyces cerevisiae YNL245C CWC25 Component of a complex containing Cef1p, involved in pre-mRNA splicing; has similarity to S. pombe Cwf25p
similar to uniprot|P53852 Saccharomyces cerevisiae YNL247W Protein required for cell viability
similar to uniprot|P47139 Saccharomyces cerevisiae YJR098C Hypothetical ORF
similar to uniprot|P47138 Saccharomyces cerevisiae YJR097W JJJ3 Protein required along with Dph1p Dph2p Kti11p and Dph5p for synthesis of diphthamide which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p) contains a DnaJ-like domain
highly similar to uniprot|Q01080 Saccharomyces cerevisiae YNL248C RPA49 RNA polymerase I subunit A49
similar to uniprot|P53583 Saccharomyces cerevisiae YNL249C MPA43 Mitochondrial protein
similar to uniprot|P12753 Saccharomyces cerevisiae YNL250W RAD50 Subunit of MRX complex with Mre11p and Xrs2p involved in processing double-strand DNA breaks in vegetative cells initiation of meiotic DSBs telomere maintenance and nonhomologous end joining
similar to uniprot|P53617 Saccharomyces cerevisiae YNL251C NRD1 RNA-binding protein that interacts with the C-terminal domain of the RNA polymerase II large subunit (Rpo21p) required for transcription termination and 3' end maturation of nonpolyadenylated RNAs
mitochondrial 54S ribosomal protein YmL17/YmL30
similar to uniprot|P36528 Saccharomyces cerevisiae YNL252C MRPL17 Mitochondrial ribosomal protein of the large subunit
similar to uniprot|P53851 Saccharomyces cerevisiae YNL253W TEX1 transcription export complex component
some similarities with uniprot|P53850 Saccharomyces cerevisiae YNL254C Hypothetical ORF
highly similar to uniprot|P53849 Saccharomyces cerevisiae YNL255C
similar to uniprot|P53848 Saccharomyces cerevisiae YNL256W FOL1 Multifunctional enzyme of the folic acid biosynthesis pathway has dihydropteroate synthetase dihydro-6-hydroxymethylpterin pyrophosphokinase and dihydroneopterin aldolase activities
similar to uniprot|P53318 Saccharomyces cerevisiae YGR255C COQ6 Putative flavin-dependent monooxygenase involved in ubiquinone (Coenzyme Q) biosynthesis located on the matrix side of the mitochondrial inner membrane
similar to uniprot|P54857 Saccharomyces cerevisiae YDR058C TGL2 Triglyceride Lipase
similar to uniprot|P38717 Saccharomyces cerevisiae YNL257C SIP3 Protein that activates transcription through interaction with DNA-bound Snf1p C-terminal region has a putative leucine zipper motif potential Cdc28p substrate and to uniprot|P38851 Saccharomyces cerevisiae YHR155W YSP1 Hypothetical ORF
similar to uniprot|P53847 Saccharomyces cerevisiae YNL258C DSL1 Endoplasmic reticulum (ER)-localized peripheral membrane protein required for Golgi-to-ER retrograde traffic component of the ER target site that interacts with coatomer the major component of the COPI vesicle protein coat
highly similar to uniprot|P38636 Saccharomyces cerevisiae YNL259C
similar to uniprot|P53846 Saccharomyces cerevisiae YNL260C Protein required for cell viability
some similarities with uniprot|P38852 Saccharomyces cerevisiae YHR156C LIN1 Nuclear protein that physically interacts with Irr1p a component of the cohesin complex may link together proteins involved in chromosome segregation mRNA splicing and DNA replication
highly similar to uniprot|P50874 Saccharomyces cerevisiae YNL261W ORC5 Subunit of the origin recognition complex which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing
highly similar to uniprot|P21951 Saccharomyces cerevisiae YNL262W POL2 Catalytic subunit of DNA polymerase epsilon one of the major chromosomal DNA replication polymerases characterized by processivity and proofreading exonuclease activity also involved in DNA synthesis during DNA repair
similar to uniprot|P53845 Saccharomyces cerevisiae YNL263C
weakly similar to uniprot|P52868 Saccharomyces cerevisiae YGL128C
similar to uniprot|P53844 Saccharomyces cerevisiae YNL264C PDR17 Phosphatidylinositol transfer protein (PITP) downregulates Plb1p-mediated turnover of phosphatidylcholine found in the cytosol and microsomes homologous to Pdr16p deletion affects phospholipid composition
similar to uniprot|P53120 Saccharomyces cerevisiae YGL140C Hypothetical ORF
similar to uniprot|P53044 Saccharomyces cerevisiae YGR048W UFD1 Protein that interacts with Cdc48p and Npl4p involved in recognition of polyubiquitinated proteins and their presentation to the 26S proteasome for degradation involved in transporting proteins from the ER to the cytosol
similar to uniprot|P33339 Saccharomyces cerevisiae YGR047C
similar to uniprot|P53843 Saccharomyces cerevisiae YNL265C IST1 Putative translation initiation factor as suggested by computational analysis of large-scale protein-protein interaction data
similar to uniprot|P53230 Saccharomyces cerevisiae YGR046W Essential protein of unknown function mRNA is targeted to the bud via the mRNA transport system involving She2p
similar to uniprot|P39104 Saccharomyces cerevisiae YNL267W PIK1 Phosphatidylinositol 4-kinase catalyzes first step in the biosynthesis of phosphatidylinositol-4 5-biphosphate may control cytokineses through the actin cytoskeleton
similar to uniprot|P32487 Saccharomyces cerevisiae YNL268W LYP1 Lysine permease one of three amino acid permeases (Alp1p Can1p Lyp1p) responsible for uptake of cationic amino acids
similar to uniprot|P04817 Saccharomyces cerevisiae YEL063C CAN1 Plasma membrane arginine permease requires phosphatidyl ethanolamine (PE) for localization exclusively associated with lipid rafts mutation confers canavanine resistance
some similarities with uniprot|P41832 Saccharomyces cerevisiae YNL271C BNI1 Formin nucleates the formation of linear actin filaments involved in cell processes such as budding and mitotic spindle orientation which require the formation of polarized actin cables functionally redundant with BNR1
weakly similar to uniprot|P17065 Saccharomyces cerevisiae YNL272C SEC2 Guanyl-nucleotide exchange factor for the small G-protein Sec4p located on cytoplasmic vesicles essential for post-Golgi vesicle transport
similar to uniprot|P39981 Saccharomyces cerevisiae YEL064C AVT2 Putative transporter member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters
similar to uniprot|P53840 Saccharomyces cerevisiae YNL273W TOF1 Protein that interacts with topoisomerase I
weakly similar to uniprot|P13365 Saccharomyces cerevisiae YAL040C
similar to uniprot|Q12232 Saccharomyces cerevisiae YOR154W Hypothetical ORF
similar to uniprot|P23255 Saccharomyces cerevisiae YCR042C TAF2 TFIID subunit (150 kDa) involved in RNA polymerase II transcription initiation
similar to uniprot|P53839 Saccharomyces cerevisiae YNL274C Putative hydroxyisocaproate dehydrogenase
similar to uniprot|P25361 Saccharomyces cerevisiae YCR043C Hypothetical ORF
highly similar to uniprot|P53838 Saccharomyces cerevisiae YNL275W
similar to uniprot|P25625 Saccharomyces cerevisiae YCR044C PER1 Vacuolar membrane protein that seems to be involved in Mn2 homeostasis mutant is dependent on activation of the unfolded protein response pathway for viability
weakly similar to uniprot|P40014 Saccharomyces cerevisiae YER018C
similar to uniprot|P40015 Saccharomyces cerevisiae YER019W ISC1 Inositol phosphosphingolipid phospholipase C hydrolyzes inositolphosphosphingolipids activated by phosphatidylserine cardiolipin and phosphatidylglycerol mediates Na and Li halotolerance contains a P loop-like domain
similar to uniprot|Q06321 Saccharomyces cerevisiae YLR189C ATG26 UDP-glucose:sterol glucosyltransferase conserved enzyme involved in synthesis of sterol glucoside membrane lipids involved in autophagy
similar to uniprot|P08465 Saccharomyces cerevisiae YNL277W MET2 L-homoserine-O-acetyltransferase catalyzes the conversion of homoserine to O-acetyl homoserine which is the first step of the methionine biosynthetic pathway
similar to uniprot|P33310 Saccharomyces cerevisiae YLR188W MDL1 Half-type ATP-binding cassette (ABC) transporter of the inner mitochondrial membrane mediates export of peptides generated upon proteolysis of mitochondrial proteins plays a role in the regulation of cellular resistance to oxidative stress
similar to Saccharomyces cerevisiae YLR187W SKG3 Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; potential Cdc28p substrate And to YNL278W uniprot|P53836 Saccharomyces cerevisiae YNL278W CAF120 Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex involved in controlling mRNA initiation, elongation, and degradation
similar to uniprot|P53835 Saccharomyces cerevisiae YNL279W PRM1 Pheromone-regulated multispanning membrane protein involved in membrane fusion during mating predicted to have 5 transmembrane segments and a coiled coil domain localizes to the shmoo tip regulated by Ste12p
highly similar to uniprot|Q06287 Saccharomyces cerevisiae YLR186W EMG1 Protein required for the maturation of the 18S rRNA and for 40S ribosome production associated with spindle/microtubules nuclear localization depends on physical interaction with Nop14p may bind snoRNAs
similar to uniprot|Q04377 Saccharomyces cerevisiae YDR499W LCD1 Essential protein required for the DNA integrity checkpoint pathways interacts physically with Mec1p putative homolog of S. pombe Rad26 and human ATRIP
highly similar to uniprot|P49166 Saccharomyces cerevisiae YLR185W RPL37A protein and to uniprot|P51402 Saccharomyces cerevisiae YDR500C RPL37B protein, components of the large (60S) ribosomal subunit
similar to uniprot|Q04383 Saccharomyces cerevisiae YDR501W PLM2 Plasmid Maintenance and to uniprot|Q06266 YLR183C Saccharomyces cerevisiae TOS4 Transcription factor that binds to a number of promoter regions, particularly promoters of some genes involved in pheromone response and cell cycle; potential Cdc28p substrate; expression is induced in G1 by bound SBF
similar to uniprot|P09959 Saccharomyces cerevisiae YLR182W SWI6 Transcription cofactor forms complexes with DNA-binding proteins Swi4p and Mbp1p to regulate transcription at the G1/S transition involved in meiotic gene expression localization regulated by phosphorylation potential Cdc28p substrate
weakly similar to uniprot|Q07057 Saccharomyces cerevisiae YLR181C VTA1 Protein involved in endosomal protein sorting binds to Vps20 and Vps4 and may regulate Vps4function has coiled-coil domains mutants show class E vacuolar-protein sorting defects
highly similar to uniprot|P10659 Saccharomyces cerevisiae YDR502C and to uniprot|P19358 SAM1 S-adenosylmethionine synthetase catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine one of two differentially regulated isozymes (Sam1p and Sam2p)
similar to uniprot|Q04396 Saccharomyces cerevisiae YDR503C LPP1 Lipid phosphate phosphatase catalyzes Mg(2)-independent dephosphorylation of phosphatidic acid (PA) lysophosphatidic acid and diacylglycerol pyrophosphate involved in control of the cellular levels of phosphatidylinositol and PA
similar to uniprot|P14306 Saccharomyces cerevisiae YLR178C TFS1 Carboxypeptidase Y inhibitor (putative) lipid binding protein supressor of a cdc25 mutation
weakly similar to Saccharomyces cerevisiae YLR177W Hypothetical ORF and to YDR505C uniprot|P50896 Saccharomyces cerevisiae YDR505C PSP1 Asn and gln rich protein of unknown function; high-copy suppressor of POL1 (DNA polymerase alpha) and partial suppressor of CDC2 (polymerase delta) and CDC6 (pre-RC loading factor) mutations; overexpression results in growth inhibition
similar to uniprot|Q04399 Saccharomyces cerevisiae YDR506C Hypothetical ORF
similar to uniprot|Q12263 Saccharomyces cerevisiae YDR507C
highly similar to uniprot|Q12306 Saccharomyces cerevisiae YDR510W
similar to uniprot|P48813 Saccharomyces cerevisiae YDR508C GNP1 High-affinity glutamine permease also transports Leu Ser Thr Cys Met and Asn expression is fully dependent on Grr1p and modulated by the Ssy1p-Ptr3p-Ssy5p (SPS) sensor of extracellular amino acids
highly similar to uniprot|Q96VH4 Saccharomyces cerevisiae YCL026C-B Hypothetical ORF
weakly similar to uniprot|P11710 Saccharomyces cerevisiae YCL027W FUS1 Membrane protein localized to the shmoo tip required for cell fusion expression regulated by mating pheromone proposed to coordinate signaling fusion and polarization events required for fusion potential Cdc28p substrate
some similarities with uniprot|P36110 Saccharomyces cerevisiae YKR013W PRY2 Protein of unknown function, has similarity to Pry1p and Pry3p and to the plant PR-1 class of pathogen related proteins
some similarities with uniprot|Q8TFP8 Saccharomyces cerevisiae YCL028W RNQ1 [PIN(+)] prion an infectious protein conformation that is generally an ordered protein aggregate
some similarities with uniprot|P11709 Saccharomyces cerevisiae YCL029C BIK1 Microtubule-associated protein component of the interface between microtubules and kinetochore involved in sister chromatid separation essential in polyploid cells but not in haploid or diploid cells ortholog of mammalian CLIP-170
highly similar to uniprot|P00815 Saccharomyces cerevisiae YCL030C
similar to uniprot|Q02562 Saccharomyces cerevisiae YDR511W ACN9 Protein of the mitochondrial intermembrane space required for acetate utilization and gluconeogenesis has orthologs in higher eukaryotes
similar to uniprot|P25368 Saccharomyces cerevisiae YCL031C RRP7 involved in rRNA processing
similar to uniprot|P25344 Saccharomyces cerevisiae YCL032W STE50 Protein involved in mating response invasive/filamentous growth and osmotolerance acts as an adaptor that links G protein-associated Cdc42p-Ste20p complex to the effector Ste11p to modulate signal transduction
some similarities with uniprot|Q04406 Saccharomyces cerevisiae YDR512C EMI1 Non-essential protein of unknown function required for transcriptional induction of the early meiotic-specific transcription factor IME1 also required for sporulation
similar to uniprot|P25566 Saccharomyces cerevisiae YCL033C Hypothetical ORF
similar to uniprot|P25369 Saccharomyces cerevisiae YCL034W LSB5 Protein of unknown function binds Las17p which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization
similar to uniprot|P17695 Saccharomyces cerevisiae YDR513W TTR1 Glutaredoxin (thioltransferase) (glutathione reductase)and similar to uniprot|P25373 Saccharomyces cerevisiae YCL035c
similar to uniprot|P25370 Saccharomyces cerevisiae YDR514C Hypothetical ORF and similar to YCL036w
some similarities with uniprot|P25567 Saccharomyces cerevisiae YCL037C SRO9 Associates with translating ribosomes may function in the cytoplasm to modulate mRNA translation may be involved in organization of actin filaments RNA binding protein with La motif
similar to uniprot|P25568 Saccharomyces cerevisiae YCL038C ATG22 Protein required for the breakdown of autophagic vesicles in the vacuole during autophagy putative integral membrane protein that localizes to vacuolar membranes and punctate structures attached to the vacuole
similar to uniprot|P25569 Saccharomyces cerevisiae YCL039W
highly similar to uniprot|P17709 Saccharomyces cerevisiae YCL040W GLK1 Glucokinase catalyzes the phosphorylation of glucose at C6 in the first irreversible step of glucose metabolism one of three glucose phosphorylating enzymes expression regulated by non-fermentable carbon sources
similar to uniprot|Q04410 Saccharomyces cerevisiae YDR517W GRH1 Golgi localized protein component of the spindle assembly checkpoint homolog of human GRASP65 which functions in postmitotic reassembly of Golgi stacks
similar to uniprot|P17967 Saccharomyces cerevisiae YCL043C PDI1 Protein disulfide isomerase and similar to uniprot|P32474 Saccharomyces cerevisiae YDR518w
similar to uniprot|P25573 Saccharomyces cerevisiae YCL044C
similar to uniprot|P25574 Saccharomyces cerevisiae YCL045C
similar to uniprot|P32472 Saccharomyces cerevisiae YDR519W FPR2 Membrane-bound peptidyl-prolyl cis-trans isomerase (PPIase) binds to the drugs FK506 and rapamycin expression pattern suggests possible involvement in ER protein trafficking
similar to uniprot|P25576 Saccharomyces cerevisiae YCL047C Hypothetical ORF
similar to uniprot|Q04411 Saccharomyces cerevisiae YDR520C Hypothetical ORF
similar to uniprot|P25380 Saccharomyces cerevisiae YCL048W SPS22 Protein of unknown function redundant with Sps2p for the organization of the beta-glucan layer of the spore wall and similar to YDR522c uniprot|P08459 Saccharomyces cerevisiae and weakly similar to YBR078w uniprot|P38248 Saccharomyces cerevisiae and weakly similar to YDR055w uniprot|Q12355 Saccharomyces cerevisiae
similar to uniprot|P08458 Saccharomyces cerevisiae YDR523C SPS1 dispensable for mitosis involved in middle/late stage of meiosis required for spore wall formation serine/threonine kinase homologous to Ste20p expressed in middle/late meiosis
weakly similar to uniprot|Q04412 Saccharomyces cerevisiae YDR524C AGE1
some similarities with uniprot|Q3E6R4 Saccharomyces cerevisiae YDR524C-B
similar to uniprot|P32460 Saccharomyces cerevisiae YIR030C DCG1 Protein of unknown function expression is sensitive to nitrogen catabolite repression and regulated by Dal80p contains transmembrane domain
similar to uniprot|Q04418 Saccharomyces cerevisiae YDR527W
weakly similar to uniprot|Q6Q537 Saccharomyces cerevisiae YDR532C Protein of unknown function that localizes to the nuclear side of the spindle pole body and along short spindles forms a complex with Spc105p
similar to uniprot|Q04430 Saccharomyces cerevisiae YDR531W Pantothenate kinase (ATP:D-pantothenate 4'-phosphotransferase EC 2.7.1.33) catalyzes the first committed step in the universal biosynthetic pathway leading to CoA.
similar to uniprot|P16550 Saccharomyces cerevisiae YCL050C and similar to uniprot|P16550 Saccharomyces cerevisiae YDR530c
highly similar to uniprot|P00128 Saccharomyces cerevisiae YDR529C
weakly similar to uniprot|P25579 Saccharomyces cerevisiae YCL051W LRE1 Protein involved in control of cell wall structure and stress response inhibits Cbk1p protein kinase activity overproduction confers resistance to cell-wall degrading enzymes
similar to uniprot|P25580 Saccharomyces cerevisiae YCL052C PBN1 Essential component of glycosylphosphatidylinositol-mannosyltransferase I required for the autocatalytic post-translational processing of the protease B precursor Prb1p localizes to ER in lumenal orientation homolog of mammalian PIG-X
similar to uniprot|P25582 Saccharomyces cerevisiae YCL054W SPB1 AdoMet-dependent methyltransferase involved in rRNA processing and 60S ribosomal subunit maturation methylates G2922 in the putative tRNA docking site of the large subunit rRNA and in the absence of snR52 U2921 suppressor of PAB1 mutants
highly similar to uniprot|P25583 Saccharomyces cerevisiae YCL055W KAR4 Transcription factor required for induction of KAR3 and CIK1 during mating also required during meiosis exists in two forms a slower-migrating form more abundant during vegetative growth and a faster-migrating form induced by pheromone
similar to uniprot|P25375 Saccharomyces cerevisiae YCL057W PRD1 Zinc metalloendopeptidase found in the cytoplasm and intermembrane space of mitochondria
similar to uniprot|Q96VH5 Saccharomyces cerevisiae YCL057C-A
similar to uniprot|Q2V2Q1 Saccharomyces cerevisiae YCL058W-A
90S preribosome/SSU processome component KRR1
highly similar to uniprot|P25586 Saccharomyces cerevisiae YCL059C KRR1 Essential nucleolar protein required for the synthesis of 18S rRNA and for the assembly of 40S ribosomal subunit
weakly similar to uniprot|P25588 Saccharomyces cerevisiae YCL061C MRC1 S-phase checkpoint protein found at replication forks required for DNA replication also required for Rad53p activation during DNA replication stress where it forms a replication-pausing complex with Tof1p and is phosphorylated by Mec1p protein involved in replication checkpoint
similar to uniprot|P25591 Saccharomyces cerevisiae YCL063W VAC17 vacuole inheritance
highly similar to uniprot|Q2UD26 Aspergillus oryzae AO090012000349 Choline dehydrogenase and related flavoproteins
similar to uniprot|P40988 Saccharomyces cerevisiae YMR319C FET4 Low-affinity Fe(II) transporter of the plasma membrane
weakly similar to uniprot|P53053 Saccharomyces cerevisiae YGL263W COS12 Protein of unknown function member of a family of conserved often subtelomerically- encoded proteins
some similarities with uniprot|P32319 Saccharomyces cerevisiae YBL017C PEP1 Type I transmembrane sorting receptor for multiple vacuolar hydrolases cycles between the late-Golgi and prevacuolar endosome-like compartments