Zygosaccharomyces rouxii strain CBS732 chromosome B complete sequence.
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Zygosaccharomyces.
Comparative genomics of protoploid Saccharomycetaceae
Submitted (25-SEP-2017) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (04-JUN-2009) Genoscope - Centre National de Sequencage : BP 191 91006 EVRY cedex - FRANCE (E-mail : seqref@genoscope.cns.fr - Web : www.genoscope.cns.fr)
PROVISIONAL REFSEQ: This record has not yet been subject to final\nNCBI review. The reference sequence is identical to CU928174.\nThe Zygosaccharomyces rouxii sequence is made of 7 chromosomes (A\nto G). The sequence was annotated by the Genolevures Consortium.\nFor more information go to\nhttp://cbi.labri.fr/Genolevures.\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: INSDC submitter\nAnnotation Status :: Full annotation\nAnnotation Pipeline :: Eukaryotic Annotation Propagation Pipeline\n##Genome-Annotation-Data-END##
weakly similar to uniprot|P47187 Saccharomyces cerevisiae YJR161C COS5 Protein of unknown function member of a family of conserved often subtelomerically-encoded proteins
some similarities with uniprot|P32319 Saccharomyces cerevisiae YBL017C PEP1 Type I transmembrane sorting receptor for multiple vacuolar hydrolases cycles between the late-Golgi and prevacuolar endosome-like compartments
similar to uniprot|P15365 Saccharomyces cerevisiae YJR152W DAL5
similar to uniprot|P53183 Saccharomyces cerevisiae YGL039W and similar to uniprot|P53111 Saccharomyces cerevisiae YGL157W
similar to uniprot|P32331 Saccharomyces cerevisiae YPR058W YMC1 Putative mitochondrial inner membrane transporter member of the mitochondrial carrier (MCF) family
highly similar to uniprot|P23641 Saccharomyces cerevisiae YJR077C MIR1 Mitochondrial phosphate carrier imports inorganic phosphate into mitochondria functionally redundant with Pic2p but more abundant than Pic2 under normal conditions
highly similar to uniprot|Q06703 Saccharomyces cerevisiae YLR308W CDA2 Chitin deacetylase together with Cda1p involved in the biosynthesis ascospore wall component chitosan required for proper rigidity of the ascospore wall
similar to uniprot|Q06704 Saccharomyces cerevisiae YLR309C IMH1 Protein involved in vesicular transport mediates transport between an endosomal compartment and the Golgi contains a Golgi-localization (GRIP) domain that interacts with activated Arl1p-GTP to localize Imh1p to the Golgi
similar to uniprot|P04821 Saccharomyces cerevisiae YLR310C CDC25 Membrane bound guanine nucleotide exchange factor (GEF or GDP-release factor) indirectly regulates adenylate cyclase through activation of Ras1p and Ras2p by stimulating the exchange of GDP for GTP required for progression through G1
highly similar to uniprot|P29055 Saccharomyces cerevisiae YPR086W SUA7 Transcription factor TFIIB a general transcription factor required for transcription initiation and start site selection by RNA polymerase II
highly similar to uniprot|P04802 Saccharomyces cerevisiae YLL018C DPS1 Cytoplasmic aspartyl-tRNA synthetase homodimeric enzyme that catalyzes the specific aspartylation of tRNA(Asp) class II aminoacyl tRNA synthetase binding to its own mRNA may confer autoregulation
highly similar to uniprot|Q3E731 Saccharomyces cerevisiae YLL018C-A COX19 Cytochrome c oxidase assembly protein
similar to uniprot|P32350 Saccharomyces cerevisiae YLL019C KNS1 Nonessential putative protein kinase of unknown cellular role member of the LAMMER family of protein kinases which are serine/threonine kinases also capable of phosphorylating tyrosine residues
weakly similar to uniprot|Q06159 Saccharomyces cerevisiae YLR312C Hypothetical ORF
mitochondrial 54S ribosomal protein YmL15
similar to uniprot|P36523 Saccharomyces cerevisiae YLR312W-A MRPL15 Mitochondrial ribosomal protein of the large subunit
weakly similar to uniprot|P23201 Saccharomyces cerevisiae YLL021W SPA2 Component of the polarisome which functions in actin cytoskeletal organization during polarized growth acts as a scaffold for Mkk1p and Mpk1p cell wall integrity signaling components potential Cdc28p substrate
weakly similar to uniprot|P38995 Saccharomyces cerevisiae YDR270w CCC2 probable copper-transporting ATPase P16.2.f2.1
similar to uniprot|P32457 Saccharomyces cerevisiae YLR314C CDC3 Component of the septin ring of the mother-bud neck that is required for cytokinesis septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane and they comprise the 10nm filaments seen with EM
weakly similar to uniprot|Q12373 Saccharomyces cerevisiae YLL022C HIF1 Non-essential component of the HAT-B histone acetyltransferase complex (Hat1p-Hat2p-Hif1p) localized to the nucleus has a role in telomeric silencing
similar to uniprot|Q12164 Saccharomyces cerevisiae YLL023C Hypothetical ORF
highly similar to uniprot|P10592 Saccharomyces cerevisiae YLL024C SSA2 member of 70 kDa heat shock protein family
similar to gnl|GLV|CAGL0E03608g Candida glabrata CAGL0E03608g and some similarites with YHL023C uniprot|P38742 Saccharomyces cerevisiae YHL023C RMD11 Protein required for sporulation
some similarities with uniprot|P38741 Saccharomyces cerevisiae YHL024W RIM4 Putative RNA-binding protein required for the expression of early and middle sporulation genes
highly similar to uniprot|P31539 Saccharomyces cerevisiae YLL026W HSP104 Heat shock protein that cooperates with Ydj1p (Hsp40) and Ssa1p (Hsp70) to refold and reactivate previously denatured aggregated proteins responsive to stresses including: heat ethanol and sodium arsenite involved in [PSI ] propagation
some similarities with uniprot|Q07821 Saccharomyces cerevisiae YLL027W ISA1 Mitochondrial matrix protein involved in biogenesis of the iron-sulfur (Fe/S) cluster of Fe/S proteins isa1 deletion causes loss of mitochondrial DNA and respiratory deficiency depletion reduces growth on nonfermentable carbon sources
similar to uniprot|Q07824 Saccharomyces cerevisiae YLL028W TPO1 Proton-motive-force-dependent multidrug transporter of the major facilitator superfamily able to transport eight different compounds including polyamines quinidine cycloheximide and nystatin involved in excess spermidine detoxification
similar to uniprot|Q07825 Saccharomyces cerevisiae YLL029W Hypothetical ORF
similar to uniprot|Q07830 Saccharomyces cerevisiae YLL031C
weakly similar to uniprot|P18888 Saccharomyces cerevisiae YHL025W SNF6 Involved in global regulation of transcription subunit of the chromatin remodeling Snf/Swi complex
similar to uniprot|P28320 Saccharomyces cerevisiae YKL095W YJU2 Essential nuclear protein putative spliceosomal component involved in mRNA splicing based on computational analysis of large-scale protein-protein interaction data
some similarities with uniprot|P38749 Saccharomyces cerevisiae YHL009C YAP3 bZIP transcription factor
similar to uniprot|Q75DK5 Ashbya gossypii ABR016C ABR016Cp and weakly similar to YKL090W uniprot|P36075 Saccharomyces cerevisiae YKL090W CUE2 Protein of unknown function has two CUE domains that bind ubiquitin which may facilitate intramolecular monoubiquitination
weakly similar to uniprot|P35201 Saccharomyces cerevisiae YKL089W MIF2 Kinetochore protein with homology to human CENP-C required for structural integrity of the spindle during anaphase spindle elongation interacts with histones H2A H2B and H4 phosphorylated by Ipl1p
weakly similar to uniprot|Q03497 Saccharomyces cerevisiae YHL007C STE20 Signal transducing kinase of the PAK (p21-activated kinase) family involved in pheromone response and pseudohyphal/invasive growth pathways activated by Cdc42p binds Ste4p at a GBB motif present in noncatalytic domains of PAK kinases
similar to uniprot|P33202 Saccharomyces cerevisiae YKL010C UFD4 Ubiquitin-protein ligase (E3) that interacts with Rpt4p and Rpt6p two subunits of the 19S particle of the 26S proteasome cytoplasmic E3 involved in the degradation of ubiquitin fusion proteins
highly similar to uniprot|P33201 Saccharomyces cerevisiae YKL009W MRT4 Protein involved in mRNA turnover and ribosome assembly localizes to the nucleolus
weakly similar to uniprot|P38751 Saccharomyces cerevisiae YHL006C SHU1 Protein involved in recombination
mitochondrial 37S ribosomal protein MRP4
similar to uniprot|P32902 Saccharomyces cerevisiae YHL004W MRP4 Mitochondrial ribosomal protein of the small subunit
similar to uniprot|P38703 Saccharomyces cerevisiae YHL003C LAG1 Ceramide synthase component involved in synthesis of ceramide from C26(acyl)-coenzyme A and dihydrosphingosine or phytosphingosine functionally equivalent to Lac1p and similar to YKL008C uniprot|P28496 Saccharomyces cerevisiae YKL008C LAC1 Ceramide synthase component involved in synthesis of ceramide from C26(acyl)-coenzyme A and dihydrosphingosine or phytosphingosine functionally equivalent to Lag1p
similar to uniprot|P38753 Saccharomyces cerevisiae YHL002W HSE1 Subunit of the endosomal Vps27p-Hse1p complex required for sorting of ubiquitinated membrane proteins into intralumenal vesicles prior to vacuolar degradation as well as for recycling of Golgi proteins and formation of lumenal membranes
highly similar to gnl|GLV|CAGL0K02783g Candida glabrata CAGL0K02783g and similar to YKL007W uniprot|P28495 Saccharomyces cerevisiae YKL007W CAP1 Alpha subunit of the capping protein (CP) heterodimer (Cap1p and Cap2p) which binds to the barbed ends of actin filaments preventing further polymerization localized predominantly to cortical actin patches
highly similar to uniprot|P43682 Saccharomyces cerevisiae YKL006C-A SFT1 Intra-Golgi v-SNARE required for transport of proteins between an early and a later Golgi compartment
highly similar to uniprot|P36105 Saccharomyces cerevisiae YKL006W RPL14A and to uniprot|P38754 Saccharomyces cerevisiae YHL001W RPL14B Protein component of the large (60S) ribosomal subunit
similar to uniprot|P36106 Saccharomyces cerevisiae YKL005C BYE1 Negative regulator of transcription elongation contains a TFIIS-like domain and a PHD finger multicopy suppressor of temperature-sensitive ess1 mutations probably binds RNA polymerase II large subunit
similar to uniprot|P36107 Saccharomyces cerevisiae YKL004W AUR1 Phosphatidylinositol:ceramide phosphoinositol transferase (IPC synthase) required for sphingolipid synthesis can mutate to confer aureobasidin A resistance
mitochondrial 37S ribosomal protein YmS16
highly similar to uniprot|P28778 Saccharomyces cerevisiae YKL003C MRP17 Mitochondrial ribosomal protein of the small subunit MRP17 exhibits genetic interactions with PET122 encoding a COX3-specific translational activator
highly similar to uniprot|P36108 Saccharomyces cerevisiae YKL002W DID4 Class E Vps protein of the ESCRT-III complex required for sorting of integral membrane proteins into lumenal vesicles of multivesicular bodies and for delivery of newly synthesized vacuolar enzymes to the vacuole involved in endocytosis[INTRON]
highly similar to uniprot|Q02196 Saccharomyces cerevisiae YKL001C MET14 Adenylylsulfate kinase required for sulfate assimilation and involved in methionine metabolism
highly similar to uniprot|P21576 Saccharomyces cerevisiae YKR001C VPS1 GTPase required for vacuolar protein sorting, functions in actin cytoskeleton organization via its interaction with Sla1p
highly similar to uniprot|P29468 Saccharomyces cerevisiae YKR002W PAP1 Poly(A) polymerase one of three factors required for mRNA 3'-end polyadenylation forms multiprotein complex with polyadenylation factor I (PF I) also required for mRNA nuclear export may also polyadenylate rRNAs
highly similar to uniprot|P38755 Saccharomyces cerevisiae YHR001W OSH7 Member of an oxysterol-binding protein family with seven members in S. cerevisiae family members have overlapping redundant functions in sterol metabolism and collectively perform a function essential for viability
similar to uniprot|Q02202 Saccharomyces cerevisiae YKR004C ECM9 Non-essential protein of unknown function
some similarities with uniprot|Q02203 Saccharomyces cerevisiae YKR005C Hypothetical ORF
similar to uniprot|Q02204 Saccharomyces cerevisiae YKR006C MRPL13 Mitochondrial ribosomal protein of the large subunit not essential for mitochondrial translation
weakly similar to uniprot|Q02205 Saccharomyces cerevisiae YKR007W MEH1
similar to uniprot|Q02206 Saccharomyces cerevisiae YKR008W RSC4 One of 15 subunits of the 'Remodel the Structure of Chromatin' (RSC) complex found in close proximity to nucleosomal DNA displaced from the surface of nucleosomal DNA after chromatin remodeling
similar to uniprot|P27810 Saccharomyces cerevisiae YOR099w KTR1 mannosyltransferase involved in n-linked and o-linked glycosylation
similar to uniprot|P37299 Saccharomyces cerevisiae YHR001W-A QCR10 8.5 kDa subunit of the ubiqunol-cytochrome c oxidoreductase complex
similar to uniprot|Q02207 Saccharomyces cerevisiae YKR009C FOX2 Multifunctional enzyme of the peroxisomal fatty acid beta-oxidation pathway has 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities
similar to uniprot|P38153 Saccharomyces cerevisiae YBR288C APM3 Mu3-like subunit of the yeast AP-3 complex which functions in transport of alkaline phosphatase to the vacuole via the alternate pathway clathrin associated protein medium chain
some similarities with uniprot|P18480 Saccharomyces cerevisiae YBR289W SNF5 Involved in global regulation of transcription subunit of the chromatin remodeling Snf/Swi complex
similar to uniprot|P38356 Saccharomyces cerevisiae YBR290W BSD2 Heavy metal ion homeostasis protein facilitates trafficking of Smf1p and Smf2p metal transporters to the vacuole where they are degraded controls metal ion transport prevents metal hyperaccumulation functions in copper detoxification
highly similar to uniprot|P38152 Saccharomyces cerevisiae YBR291C CTP1 Mitochondrial inner membrane citrate transporter member of the mitochondrial carrier family
highly similar to gnl|GLV|CAGL0K02915g Candida glabrata CAGL0K02915g and similar to YHR002W uniprot|P38702 Saccharomyces cerevisiae YHR002W LEU5 Mitochondrial carrier protein involved in the accumulation of CoA in the mitochondrial matrix homolog of human Graves disease protein does not encode an isozyme of Leu4p as first hypothesized
highly similar to gnl|GLV|CAGL0K02937g Candida glabrata CAGL0K02937g and similar to YKL027W uniprot|P36101 Saccharomyces cerevisiae YKL027W Hypothetical ORF
some similarities with uniprot|P36100 Saccharomyces cerevisiae YKL028W TFA1 TFIIE large subunit involved in recruitment of RNA polymerase II to the promoter activation of TFIIH and promoter opening
highly similar to uniprot|P36013 Saccharomyces cerevisiae YKL029C MAE1 Mitochondrial malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate which is a key intermediate in sugar metabolism and a precursor for synthesis of several amino acids
weakly similar to uniprot|P25386 Saccharomyces cerevisiae YDL058W USO1 involved intracellular protein transport, coiled-coil protein necessary for protein transport from ER to Golgi; Integrin analogue gene
similar to uniprot|P38757 Saccharomyces cerevisiae YHR004C NEM1 Protein of the nuclear envelope required for the spherical shape of the nucleus required for normal sporulation
some similarities with uniprot|Q04751 Saccharomyces cerevisiae YMR069W NAT4 N alpha-acetyl-transferase involved in acetylation of the N-terminal residues of histones H4 and H2A
some similarities with uniprot|P54785 Saccharomyces cerevisiae YMR070W MOT3 Nuclear transcription factor with two Cys2-His2 zinc fingers involved in repression of a subset of hypoxic genes by Rox1p repression of several DAN/TIR genes during aerobic growth and repression of ergosterol biosynthetic genes
similar to uniprot|Q04767 Saccharomyces cerevisiae YMR071C TVP18 Tlg2-Vesicle Protein of 18 kDa Integral membrane vesicle protein
similar to uniprot|P33417 Saccharomyces cerevisiae YKL032C IXR1 Protein that binds DNA containing intrastrand cross-links formed by cisplatin contains two HMG (high mobility group box) domains which confer the ability to bend cisplatin-modified DNA mediates aerobic transcriptional repression of COX5b
similar to gnl|GLV|KLLA0E18535g Kluyveromyces lactis KLLA0E18535g and weakly similar to YMR073C uniprot|Q04772 Saccharomyces cerevisiae YMR073C Hypothetical ORF
similar to uniprot|Q04773 Saccharomyces cerevisiae YMR074C Hypothetical ORF
similar to uniprot|Q04779 Saccharomyces cerevisiae YMR075W RCO1 Nuclear protein of unknown function
similar to uniprot|Q04264 Saccharomyces cerevisiae YMR076C PDS5 Protein required for establishment and maintenance of sister chromatid condensation and cohesion colocalizes with cohesin on chromosomes in an interdependent manner may function as a protein-protein interaction scaffold
some similarities with uniprot|P38750 Saccharomyces cerevisiae YHL008C Hypothetical ORF
similar to uniprot|P36097 Saccharomyces cerevisiae YKL033W Protein of unknown function localized to the cytoplasm.
similar to uniprot|P38748 YHL010C Saccharomyces cerevisiae Hypothetical ORF
highly similar to uniprot|P38689 Saccharomyces cerevisiae YHL011C PRS3 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase involved in nucleotide histidine and tryptophan biosynthesis one of a five related enzymes which are active as heteromultimeric complexes
highly similar to uniprot|Q86ZR7 YKL033W-A Saccharomyces cerevisiae YKL033W-A
highly similar to uniprot|Q12159 Saccharomyces cerevisiae YDR381W YRA1 Nuclear protein that binds to RNA and to Mex67p
similar to Saccharomyces uniprot|Q3E6R5 cerevisiae YDR381C-A Hypothetical ORF
similar to uniprot|Q754C3 Ashbya gossypii AFR147C AFR147Cp
similar to uniprot|Q12375 Saccharomyces cerevisiae YOR130C ORT1 Ornithine transporter of the mitochondrial inner membrane exports ornithine from mitochondria as part of arginine biosynthesis human ortholog is associated with hyperammonaemia-hyperornithinaemia-homocitrullinuria (HHH) syndrome
highly similar to uniprot|P02400 Saccharomyces cerevisiae YDR382W RPP2B Ribosomal protein P2 beta a component of the ribosomal stalk which is involved in the interaction between translational elongation factors and the ribosome regulates the accumulation of P1 (Rpp1Ap and Rpp1Bp) in the cytoplasm
weakly similar to uniprot|Q12493 Saccharomyces cerevisiae YDR383C NKP1
similar to uniprot|Q12359 Saccharomyces cerevisiae YDR384C ATO3 Plasma membrane protein regulation pattern suggests a possible role in export of ammonia from the cell member of the TC 9.B.33 YaaH family of putative transporters
similar to uniprot|P32772 Saccharomyces cerevisiae YDL169C UGX2
similar to uniprot|P21304 Saccharomyces cerevisiae YLR196W PWP1
highly similar to gnl|GLV|CAGL0A04059g Candida glabrata CAGL0A04059g and similar to YLR195C uniprot|P14743 Saccharomyces cerevisiae YLR195C NMT1 N- myristoyl transferase catalyzes the cotranslational covalent attachment of myristic acid to the N-terminal glycine residue of several proteins involved in cellular growth and signal transduction
weakly similar to uniprot|Q05777 Saccharomyces cerevisiae YLR194C
highly similar to uniprot|Q05776 Saccharomyces cerevisiae YLR193C Hypothetical ORF
similar to uniprot|P26370 Saccharomyces cerevisiae YDL170W UGA3 Transcriptional activator necessary for gamma-aminobutyrate (GABA)-dependent induction of GABA genes (such as UGA1 UGA2 UGA4) zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type localized to the nucleus
highly similar to uniprot|Q12680 Saccharomyces cerevisiae YDL171C GLT1 NAD()-dependent glutamate synthase (GOGAT) synthesizes glutamate from glutamine and alpha-ketoglutarate with Gln1p forms the secondary pathway for glutamate biosynthesis from ammonia expression regulated by nitrogen source
weakly similar to uniprot|Q6Q543 Saccharomyces cerevisiae YDL173W Hypothetical ORF
similar to uniprot|Q05775 Saccharomyces cerevisiae YLR192C HCR1 Dual function protein involved in translation initiation as a substoichiometric component of eukaryotic translation initiation factor 3 (eIF3) and required for processing of 20S pre-rRNA binds to eIF3 subunits Rpg1p and Prt1p and 18S rRNA
similar to uniprot|P32891 Saccharomyces cerevisiae YDL174C DLD1 D-lactate dehydrogenase oxidizes D-lactate to pyruvate transcription is heme-dependent repressed by glucose and derepressed in ethanol or lactate located in the mitochondrial inner membrane
weakly similar to uniprot|P80667 Saccharomyces cerevisiae YLR191W PEX13 Integral peroxisomal membrane receptor
some similarities with uniprot|Q06324 Saccharomyces cerevisiae YLR190W MMR1 Phosphorylated protein of the mitochondrial outer membrane localizes only to mitochondria of the bud interacts with Myo2p to mediate mitochondrial distribution to buds mRNA is targeted to the bud via the transport system involving She2p
highly similar to uniprot|P00927 Saccharomyces cerevisiae YER086W ILV1 Threonine deaminase catalyzes the first step in isoleucine biosynthesis expression is under general amino acid control ILV1 locus exhibits highly positioned nucleosomes whose organization is independent of known ILV1 regulation
similar to uniprot|P39965 Saccharomyces cerevisiae YER087W Hypothetical ORF
highly similar to uniprot|P52871 Saccharomyces cerevisiae YER019C-A SBH2 Ssh1p-Sss1p-Sbh2p complex component involved in protein translocation into the endoplasmic reticulum homologous to Sbh1p
weakly similar to uniprot|P34217 Saccharomyces cerevisiae YBL051C PIN4 Protein involved in G2/M phase progression and response to DNA damage interacts with Rad53p contains an RNA recognition motif a nuclear localization signal and several SQ/TQ cluster domains hyperphosphorylated in response to DNA damage
similar to gnl|GLV|KLLA0E20009g Kluyveromyces lactis KLLA0E20009g and weakly similar to YBL052C uniprot|P34218 Saccharomyces cerevisiae YBL052C SAS3 Histone acetyltransferase catalytic subunit of NuA3 complex that acetylates histone H3 involved in transcriptional silencing homolog of the mammalian MOZ proto-oncogene sas3 gcn5 double mutation confers lethality
weakly similar to uniprot|P40059 Saccharomyces cerevisiae YER088C DOT6 Protein of unknown function involved in telomeric gene silencing and filamentation
similar to uniprot|P34220 Saccharomyces cerevisiae YBL055C Hypothetical ORF
similar to uniprot|P34221 Saccharomyces cerevisiae YBL056W PTC3 Type 2C protein phosphatase dephosphorylates Hog1p (see also Ptc2p) to limit maximal kinase activity induced by osmotic stress dephosphorylates T169 phosphorylated Cdc28p (see also Ptc2p) role in DNA checkpoint inactivation
highly similar to uniprot|P00899 Saccharomyces cerevisiae YER090W TRP2 anthranilate synthase Component I
similar to uniprot|P34222 Saccharomyces cerevisiae YBL057C PTH2 mitochondrially-localized peptidyl-tRNA hydrolase
similar to uniprot|P34223 Saccharomyces cerevisiae YBL058W SHP1 UBX (ubiquitin regulatory X) domain-containing protein that regulates Glc7p phosphatase activity and interacts with Cdc48p interacts with ubiquitylated proteins in vivo and is required for degradation of a ubiquitylated model substrate
highly similar to uniprot|P05694 Saccharomyces cerevisiae YER091C MET6 Cobalamin-independent methionine synthase involved in amino acid biosynthesis also called N5-methyltetrahydrofolate homocysteine methyltransferase or 5-methyltetrahydropteroyltriglutamate homocysteine methyltransferase
similar to uniprot|P40060 Saccharomyces cerevisiae YER092W IES5 Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions
similar to uniprot|P40061 Saccharomyces cerevisiae YER093C TSC11 Binding Protein of TOR Protein required for cell viability
weakly similar to uniprot|P87275 Saccharomyces cerevisiae YER093C-A Hypothetical ORF
highly similar to uniprot|Q3E7A4 Saccharomyces cerevisiae YBL059ca
highly similar to uniprot|P25451 Saccharomyces cerevisiae YER094C PUP3 Beta subunit of the 20S proteasome involved in ubiquitin-dependent catabolism human homolog is subunit C10
weakly similar to uniprot|P34225 Saccharomyces cerevisiae YBL060W Hypothetical ORF
highly similar to gnl|GLV|YALI0F15477g Yarrowia lipolytica YALI0F15477g and similar to uniprot|P25454 Saccharomyces cerevisiae YER095W RAD51 Strand exchange protein forms a helical filament with DNA that searches for homology involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis homolog of Dmc1p and bacterial RecA protein
similar to uniprot|P34226 Saccharomyces cerevisiae YBL061C SKT5 Activator of Chs3p (chitin synthase III), recruits Chs3p to the bud neck via interaction with Bni4p; has similarity to Shc1p, which activates Chs3p during sporulation
similar to uniprot|P28742 Saccharomyces cerevisiae YBL063W KIP1 Kinesin-related motor protein required for mitotic spindle assembly and chromosome segregation functionally redundant with Cin8p
highly similar to gnl|GLV|KLLA0E20383g Kluyveromyces lactis KLLA0E20383g and similar to YBL064C uniprot|P34227 Saccharomyces cerevisiae YBL064C PRX1 Mitochondrial peroxiredoxin (1-Cys Prx) with thioredoxin peroxidase activity has a role in reduction of hydroperoxides induced during respiratory growth and under conditions of oxidative stress
similar to uniprot|P34228 Saccharomyces cerevisiae YBL066C SEF1 Suppressor of Essential Function putative transcription factor
similar to uniprot|P39967 Saccharomyces cerevisiae YER098W UBP9 Ubiquitin-specific protease that cleaves ubiquitin-protein fusions
highly similar to uniprot|P38620 Saccharomyces cerevisiae YER099C PRS2 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase involved in nucleotide histidine and tryptophan biosynthesis one of a five related enzymes which are active as heteromultimeric complexes
similar to uniprot|P33296 Saccharomyces cerevisiae YER100W UBC6 Ubiquitin-conjugating enzyme involved in ER-associated protein degradation located at the cytosolic side of the ER membrane tail region contains a transmembrane segment at the C-terminus substrate of the ubiquitin-proteasome pathway
similar to uniprot|P35183 Saccharomyces cerevisiae YBL069W AST1 peripheral membrane protein
highly similar to uniprot|Q3E840 Saccharomyces cerevisiae YBL071W-A KTI11 Protein required along with Dph1p Dph2p Jjj3p and Dph5p for synthesis of diphthamide which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p) may act in a complex with Dph1p and Dph2p
highly similar to uniprot|P05754 Saccharomyces cerevisiae YER102W RPS8B protein component of the small (40S) ribosomal subunit
similar to uniprot|P32357 Saccharomyces cerevisiae YBL074C AAR2 Component of the U5 snRNP required for splicing of U3 precursors originally described as a splicing factor specifically required for splicing pre-mRNA of the MATa1 cistron
highly similar to uniprot|P09435 Saccharomyces cerevisiae YBL075C SSA3 heat-inducible cytosolic member of the 70 kDa heat shock protein family
highly similar to uniprot|P09436 Saccharomyces cerevisiae YBL076C ILS1 Cytoplasmic isoleucine-tRNA synthetase target of the G1-specific inhibitor reveromycin A
similar to uniprot|P40063 Saccharomyces cerevisiae YER104W
highly similar to uniprot|P38182 Saccharomyces cerevisiae YBL078C ATG8 Protein required for autophagy
similar to uniprot|P38181 Saccharomyces cerevisiae YBL079W NUP170 Abundant subunit of the nuclear pore complex (NPC), required for proper localization of specific nucleoporins within the NPC, involved in nuclear envelope permeability and in chromosome segregation
weakly similar to uniprot|P40065 Saccharomyces cerevisiae YER106W MAM1 Monopolin kinetochore associated protein involved in chromosome attachment to meiotic spindle
similar to uniprot|P33893 Saccharomyces cerevisiae YBL080C PET112 Protein required for mitochondrial translation
weakly similar to uniprot|P38180 Saccharomyces cerevisiae YBL081W Hypothetical ORF
highly similar to uniprot|P40066 Saccharomyces cerevisiae YER107C GLE2 Component of the nuclear pore complex required for polyadenylated RNA export but not for protein import homologous to S. pombe Rae1p
some similarities with uniprot|P40068 Saccharomyces cerevisiae YER109C FLO8 Transcription factor required for flocculation diploid filamentous growth and haploid invasive growth genome reference strain S288C and most laboratory strains have a mutation in this gene
similar to uniprot|P38179 Saccharomyces cerevisiae YBL082C RHK1 Dolichol-P-Man dependent alpha(1-3) mannosyltransferase involved in the synthesis of dolichol-linked oligosaccharide donor for N-linked glycosylation of proteins
highly similar to uniprot|P40069 Saccharomyces cerevisiae YER110C KAP123 Karyopherin beta mediates nuclear import of ribosomal proteins prior to assembly into ribosomes and import of histones H3 and H4 localizes to the nuclear pore nucleus and cytoplasm exhibits genetic interactions with RAI1
similar to uniprot|P25302 Saccharomyces cerevisiae YER111C SWI4 Involved in cell cycle dependent gene expression transcription factor
weakly similar to uniprot|P40070 Saccharomyces cerevisiae YER112W LSM4 component of small nuclear ribonucleoprotein complexes involved in RNA processing, splicing, and decay
similar to uniprot|P40071 Saccharomyces cerevisiae YER113C Hypothetical ORF
similar to uniprot|P38042 Saccharomyces cerevisiae YBL084C CDC27 Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors including mitotic cyclins during the metaphase/anaphase transition
some similarities with uniprot|P39969 Saccharomyces cerevisiae YER114C BOI2 Protein implicated in polar growth functionally redundant with Boi1p interacts with bud-emergence protein Bem1p contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain
similar to gnl|GLV|KLLA0E20999g Kluyveromyces lactis KLLA0E20999g and some similarites with YBL086C uniprot|P38177 Saccharomyces cerevisiae YBL086C Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
weakly similar to uniprot|Q01684 Saccharomyces cerevisiae YER115C SPR6 sporulation-specific protein involved in sporulation
some similarities with uniprot|P40072 Saccharomyces cerevisiae YER116C SLX8 Protein containing a RING finger domain that forms a complex with Hex3p mutant phenotypes and genetic interactions suggest a possible role in resolving recombination intermediates during DNA replication or repair
highly similar to uniprot|P04451 Saccharomyces cerevisiae YER117W
similar to uniprot|P38110 Saccharomyces cerevisiae YBL088C TEL1 Protein kinase primarily involved in telomere length regulation contributes to cell cycle checkpoint control in response to DNA damage functionally redundant with Mec1p homolog of human ataxia telangiectasia (ATM) gene
similar to uniprot|P40073 Saccharomyces cerevisiae YER118C SHO1 Transmembrane osmosensor participates in activation of both the Cdc42p- and MAP kinase-dependent filamentous growth pathway and the high-osmolarity glycerol response pathway
similar to uniprot|P40074 Saccharomyces cerevisiae YER119C AVT6 Vacuolar transporter exports aspartate and glutamate from the vacuole and to YBL089W uniprot|P38176 Saccharomyces cerevisiae YBL089W AVT5 Putative transporter, members of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters
similar to uniprot|P38175 Saccharomyces cerevisiae YBL090W MRP21 Mitochondrial ribosomal protein of the large subunit MRP21 exhibits genetic interactions with mutations in the COX2 and COX3 mRNA 5'-untranslated leader sequences
similar to uniprot|P38174 Saccharomyces cerevisiae YBL091C MAP2 Methionine aminopeptidase catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides function is partially redundant with that of Map1p
highly similar to uniprot|P40075 Saccharomyces cerevisiae YER120W
highly similar to uniprot|P38061 Saccharomyces cerevisiae YBL092W RPL32 Protein component of the large (60S) ribosomal subunit has similarity to rat L32 ribosomal protein
highly similar to uniprot|P49089 Saccharomyces cerevisiae YPR145W ASN1 Asparagine synthetase isozyme of Asn2p catalyzes the synthesis of L-asparagine from L-aspartate in the asparagine biosynthetic pathway
similar to uniprot|Q06512 Saccharomyces cerevisiae YPR144C NOC4 Nucleolar protein forms a complex with Nop14p that mediates maturation and nuclear export of 40S ribosomal subunits
highly similar to uniprot|P53043 Saccharomyces cerevisiae YGR123C
similar to gnl|GLV|CAGL0D05016g Candida glabrata CAGL0D05016g and some similarites with YPR143W uniprot|Q06511 Saccharomyces cerevisiae YPR143W RRP15 Essential protein involved in pre-rRNA processing
similar to uniprot|P17119 Saccharomyces cerevisiae YPR141C KAR3 Minus-end-directed microtubule motor that functions in mitosis and meiosis localizes to the spindle pole body and localization is dependent on functional Cik1p required for nuclear fusion during mating potential Cdc28p substrate
similar to uniprot|Q6B2J1 Saccharomyces cerevisiae YPR140W
similar to uniprot|Q06508 Saccharomyces cerevisiae YPR139C VPS66
similar to uniprot|P53272 Saccharomyces cerevisiae YGR122W Hypothetical ORF
highly similar to uniprot|P53390 Saccharomyces cerevisiae YPR138C MEP3 Ammonium permease of high capacity and low affinity belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4) expression is under the nitrogen catabolite repression regulation ammonia permease or uniprot|P40260 Saccharomyces cerevisiae YGR121C MEP1
highly similar to uniprot|Q06506 Saccharomyces cerevisiae YPR137W RRP9 part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA) Rrp9p is an ortholog of the human U3-55k protein the human cDNA partially complements a yeast rrp9 null mutant. (Pluk et al. (1998) Mol. Cell. Biol. 18 488-498.) U3 small nucleolar ribonucleoprotein-associated protein involved in pre-ribosomal RNA processing.
similar to uniprot|Q01454 Saccharomyces cerevisiae YPR135W CTF4 Chromatin-associated protein required for sister chromatid cohesion interacts with DNA polymerase alpha (Pol1p) and may link DNA synthesis to sister chromatid cohesion
similar to uniprot|P53271 Saccharomyces cerevisiae YGR120C COG2 Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog8p) a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
some similarities with uniprot|P48837 Saccharomyces cerevisiae YGR119C NUP57 Essential subunit of the nuclear pore complex (NPC)
weakly similar to uniprot|P08593 Saccharomyces cerevisiae YPR134W MSS18 Protein involved in splicing intron a15beta of COX1 Involved in splicing of mitochondrial COX1 transcript
similar to uniprot|P80967 Saccharomyces cerevisiae YPR133W-A TOM5
some similarities with uniprot|Q06505 Saccharomyces cerevisiae YPR133C IWS1 Protein that interacts with Spt6p and copurifies with Spt5p and RNA polymerase II probable transcriptional elongation factor metazoan homologs contain an acidic N terminus mutations in the gene confer an Spt-phenotype
highly similar to uniprot|P32827 Saccharomyces cerevisiae YPR132W
similar to uniprot|P53270 Saccharomyces cerevisiae YGR117C Hypothetical ORF
highly similar to gnl|GLV|CAGL0D04796g Candida glabrata CAGL0D04796g and similar to uniprot|Q06504 Saccharomyces cerevisiae YPR131C NAT3 Catalytic subunit of the NatB N-terminal acetyltransferase which catalyzes acetylation of the amino-terminal methionine residues of all proteins beginning with Met-Asp or Met-Glu and of some proteins beginning with Met-Asn or Met-Met
some similarities with uniprot|P45978 Saccharomyces cerevisiae YPR129W SCD6 Protein containing an Lsm domain may bind RNA and have a role in RNA processing overproduction suppresses a null mutation in CHC1 which encodes the heavy chain of clathrin
weakly similar to uniprot|Q12433 Saccharomyces cerevisiae YOR023C AHC1 Ada Histone acetyltransferase complex component protein of the Ada histone acetyltransferase complex
similar to uniprot|Q12204 Saccharomyces cerevisiae YOR022C Hypothetical ORF
similar to uniprot|Q12296 Saccharomyces cerevisiae YOL060C
similar to uniprot|Q12100 Saccharomyces cerevisiae YDL025C Protein of unknown function potentially phosphorylated by Cdc28p
similar to uniprot|Q12265 Saccharomyces cerevisiae YOL061W PRS5 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase involved in nucleotide histidine and tryptophan biosynthesis one of a five related enzymes which are active as heteromultimeric complexes
highly similar to uniprot|Q99186 Saccharomyces cerevisiae YOL062C APM4 Clathrin associated protein medium subunit
weakly similar to uniprot|Q7LHC7 Saccharomyces cerevisiae YDL027C Hypothetical ORF
similar to uniprot|Q7LGP7 Saccharomyces cerevisiae YOL063C HUS1 Protein of unknown function
similar to uniprot|P54199 Saccharomyces cerevisiae YDL028C MPS1 Dual-specificity kinase required for spindle pole body (SPB) duplication and spindle checkpoint function substrates include SPB proteins Spc42p Spc110p and Spc98p mitotic exit network protein Mob1p and checkpoint protein Mad1p
highly similar to uniprot|P32381 Saccharomyces cerevisiae YDL029W ARP2 Essential component of the Arp2/3 complex which is a highly conserved actin nucleation center required for the motility and integrity of actin patches involved in endocytosis and membrane growth and polarity
similar to uniprot|P19736 Saccharomyces cerevisiae YDL030W PRP9 Subunit of the SF3a splicing factor complex required for spliceosome assembly
similar to uniprot|Q12389 Saccharomyces cerevisiae YDL031W DBP10 Essential protein involved in ribosome biogenesis putative ATP-dependent RNA helicase of the DEAD-box protein family
similar to uniprot|Q12093 Saccharomyces cerevisiae YDL033C SLM3 Mitochondrial protein with a potential role in protein synthesis the bacterial homolog is responsible for the 2-thiolation of mnm5s2U34 in tRNALys tRNAGlu and tRNAGln
similar to uniprot|P32179 Saccharomyces cerevisiae YOL064C MET22 Bisphosphate-3'-nucleotidase involved in salt tolerance and methionine biogenesis dephosphorylates 3'-phosphoadenosine-5'-phosphate and 3'-phosphoadenosine-5'-phosphosulfate intermediates of the sulfate assimilation pathway
similar to gnl|GLV|CAGL0K01507g Candida glabrata CAGL0K01507g and some similarites with YDL035C uniprot|Q12361 Saccharomyces cerevisiae YDL035C GPR1 Plasma membrane G- protein coupled receptor that interacts with the heterotrimeric G protein alpha subunit Gpa2p and with Plc1p sensor that integrates nutritional signals with the modulation of cell fate via PKA and cAMP synthesis
similar to uniprot|Q08227 Saccharomyces cerevisiae YOL065C INP54 Phosphatidylinositol 4 5-bisphosphate 5-phosphatase with a role in secretion localizes to the endoplasmic reticulum via the C-terminal tail lacks the Sac1 domain and proline-rich region found in the other 3 INP proteins
similar to uniprot|Q12362 Saccharomyces cerevisiae and weakly similar to YDL036C uniprot|Q12069 Saccharomyces cerevisiae YDL036C Hypothetical ORF
similar to uniprot|P12945 Saccharomyces cerevisiae YDL040C NAT1 Subunit of the N-terminal acetyltransferase NatA (Nat1p Ard1p Nat5p) N-terminally acetylates many proteins which influences multiple processes such as the cell cycle heat-shock resistance mating sporulation and telomeric silencing
similar to uniprot|P32607 Saccharomyces cerevisiae YOL067C RTG1 Transcription factor (bHLH) involved in interorganelle communication between mitochondria peroxisomes and nucleus
similar to uniprot|P53685 Saccharomyces cerevisiae YOL068C HST1 NAD()-dependent histone deacetylase essential subunit of the Sum1p/Rfm1p/Hst1p complex required for ORC-dependent silencing at HMR and for mitotic repression of mid-sporulation genes non-essential subunit of the Set3C deacetylase complex
similar to uniprot|Q07350 Saccharomyces cerevisiae YDL043C PRP11 Subunit of the SF3a splicing factor complex required for spliceosome assembly
similar to uniprot|P33895 Saccharomyces cerevisiae YOL069W NUF2 Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p) involved in chromosome segregation spindle checkpoint activity and kinetochore clustering
weakly similar to uniprot|P38866 Saccharomyces cerevisiae YHR176W FMO1 Flavin-containing monooxygenase, localized to the cytoplasmic face of the ER membrane; catalyzes oxidation of biological thiols to maintain the ER redox buffer ratio for correct folding of disulfide- bonded proteins
similar to uniprot|Q08229 Saccharomyces cerevisiae YOL070C Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cell periphery cytoplasm and bud neck potential Cdc28p substrate
weakly similar to uniprot|P10849 Saccharomyces cerevisiae YDL044C MTF2 Mitochondrial matrix protein that interacts with an N-terminal region of mitochondrial RNA polymerase (Rpo41p) and couples RNA processing and translation to transcription
similar to uniprot|P38913 Saccharomyces cerevisiae YDL045C FAD1 Flavin adenine dinucleotide (FAD) synthetase performs the second step in synthesis of FAD from riboflavin
mitochondrial 37S ribosomal protein YmS-T
similar to uniprot|O75012 Saccharomyces cerevisiae YDL045W-A MRP10 Mitochondrial ribosomal protein of the small subunit
highly similar to uniprot|Q08230 Saccharomyces cerevisiae YOL071W EMI5 Non-essential protein of unknown function required for transcriptional induction of the early meiotic-specific transcription factor IME1 also required for sporulation
similar to uniprot|Q12408 Saccharomyces cerevisiae YDL046W NPC2 Putative homolog of human NPC2/He1 which is a cholesterol-binding protein whose deficiency causes Niemann-Pick type C2 disease involving retention of cholesterol in lysosomes
highly similar to uniprot|P20604 Saccharomyces cerevisiae YDL047W SIT4 Type 2A-related serine-threonine phosphatase that functions in the G1/S transition of the mitotic cycle cytoplasmic and nuclear protein that modulates functions mediated by Pkc1p including cell wall and actin cytoskeleton organization
similar to uniprot|Q08231 Saccharomyces cerevisiae YOL072W THP1 Nuclear pore-associated protein forms a complex with Sac3p that is involved in transcription and in mRNA export from the nucleus contains a PAM domain implicated in protein-protein binding
weakly similar to uniprot|P48412 Saccharomyces cerevisiae YGR072W UPF3 Component of the nonsense-mediated mRNA decay (NMD) pathway along with Nam7p and Nmd2p involved in decay of mRNA containing nonsense codons
highly similar to uniprot|Q02260 Saccharomyces cerevisiae YGR074W SMD1 Homolog of human core snRNP protein D1 involved in snRNA maturation U6 snRNP protein
similar to uniprot|Q00723 Saccharomyces cerevisiae YGR075C PRP38 Unique component of the U4/U6.U5 tri-snRNP particle dispensable for spliceosome assembly but required for conformational changes which lead to catalytic activation of the spliceosome
mitochondrial 54S ribosomal protein YmL25
similar to uniprot|P23369 Saccharomyces cerevisiae YGR076C MRPL25 Mitochondrial ribosomal protein of the large subunit
similar to uniprot|Q756P6 Ashbya gossypii AER208C AER208Cp and weakly similar to YGR077C uniprot|P53248 Saccharomyces cerevisiae YGR077C PEX8 Required for peroxisome assembly peroxisome associated protein containing a PTS1 signal
similar to uniprot|Q08232 Saccharomyces cerevisiae YOL073C Hypothetical ORF
highly similar to uniprot|P48363 Saccharomyces cerevisiae YGR078C PAC10 Part of the heteromeric co-chaperone GimC/prefoldin complex which promotes efficient protein folding
similar to uniprot|Q08234 Saccharomyces cerevisiae YOL075C Hypothetical ORF
similar to uniprot|P38276 Saccharomyces cerevisiae YBR137W Hypothetical ORF
weakly similar to uniprot|P38277 Saccharomyces cerevisiae YBR138C Cytoplasmic protein of unknown function potentially phosphorylated by Cdc28p
similar to uniprot|Q12387 Saccharomyces cerevisiae YOL076W MDM20 Subunit of the NatB N-terminal acetyltransferase which catalyzes acetylation of the amino-terminal methionine residues of all proteins beginning with Met-Asp or Met-Glu and of some proteins beginning with Met-Asn or Met-Met involved in mitochondrial inheritance and actin assembly
highly similar to uniprot|Q08235 Saccharomyces cerevisiae YOL077C BRX1 Nucleolar protein involved in the biogenesis of large ribosomal subunits depletion leads to defects in rRNA processing and a block in the assembly of large ribosomal subunits possesses a sigma(70)-like RNA-binding motif
similar to uniprot|P81451 Saccharomyces cerevisiae YOL077W-A
similar to uniprot|P38109 Saccharomyces cerevisiae YBR139W
weakly similar to uniprot|Q08236 Saccharomyces cerevisiae YOL078W AVO1 Component of a membrane-bound complex containing the Tor2p kinase and other proteins which may have a role in regulation of cell growth
similar to uniprot|Q08237 Saccharomyces cerevisiae YOL080C REX4 Putative RNA exonuclease possibly involved in pre-rRNA processing and ribosome assembly
similar to uniprot|P18963 Saccharomyces cerevisiae YBR140c IRA1 or uniprot|P19158 Saccharomyces cerevisiae YOL081w IRA2
similar to uniprot|P38278 Saccharomyces cerevisiae YBR141C Hypothetical ORF
similar to uniprot|P38112 Saccharomyces cerevisiae YBR142W MAK5 Essential nucleolar protein putative DEAD-box RNA helicase required for maintenance of M1 dsRNA virus involved in biogenesis of large (60S) ribosomal subunits
highly similar to uniprot|P12385 Saccharomyces cerevisiae YBR143C SUP45 Translation release factor involved in translation termination mutant form acts as a recessive omnipotent suppressor
some similarities with uniprot|P35193 Saccharomyces cerevisiae YOL082W ATG19 Protein involved in the cytoplasm-to-vacuole targeting pathway and in autophagy, recognizes cargo proteins and delivers them to the preautophagosomal structure for eventual engulfment by the autophagosome and degradation
similar to uniprot|Q12252 Saccharomyces cerevisiae YOL084W PHM7 Protein of unknown function expression is regulated by phosphate levels green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and vacuole
highly similar to uniprot|P00330 Saccharomyces cerevisiae YOL086C ADH1 Alcohol dehydrogenase involved in the production of certain carboxylate esters
mitochondrial 37S ribosomal protein MRPS9
highly similar to uniprot|P38120 Saccharomyces cerevisiae YBR146W MRPS9 Mitochondrial ribosomal protein of the small subunit
similar to uniprot|Q99247 Saccharomyces cerevisiae YOL087C Hypothetical ORF
highly similar to uniprot|P20434 Saccharomyces cerevisiae YBR154C RPB5 RNA polymerase subunit ABC27 common to RNA polymerases I II and III contacts DNA and affects transactivation
similar to uniprot|P33312 Saccharomyces cerevisiae YBR153W RIB7 Diaminohydroxyphoshoribosylaminopyrimidine deaminase catalyzes the second step of the riboflavin biosynthesis pathway
weakly similar to uniprot|P38282 Saccharomyces cerevisiae YBR152W
similar to uniprot|Q99316 Saccharomyces cerevisiae YOL088C MPD2 Member of the protein disulfide isomerase (PDI) family exhibits chaperone activity overexpression suppresses the lethality of a pdi1 deletion but does not complement all Pdi1p functions undergoes oxidation by Ero1p
similar to uniprot|P38281 Saccharomyces cerevisiae YBR151W APD1 Protein of unknown function required for normal localization of actin patches and for normal tolerance of sodium ions and hydrogen peroxide localizes to both cytoplasm and nucleus
similar to uniprot|P38115 Saccharomyces cerevisiae YBR149W ARA1 Large subunit of NADP dependent arabinose dehydrogenase involved in carbohydrate metabolism small subunit is unidentified
highly similar to uniprot|P25847 Saccharomyces cerevisiae YOL090W MSH2 Protein that forms heterodimers with Msh3p and Msh6p that bind to DNA mismatches to initiate the mismatch repair process contains a Walker ATP-binding motif required for repair activity Msh2p-Msh6p binds to and hydrolyzes ATP
some similarities with uniprot|Q12411 Saccharomyces cerevisiae YOL091W SPO21 Component of the meiotic outer plaque of the spindle pole body involved in modifying the meiotic outer plaque that is required prior to prospore membrane formation
similar to uniprot|Q12010 Saccharomyces cerevisiae YOL092W Hypothetical ORF
similar to uniprot|Q12400 Saccharomyces cerevisiae YOL093W
highly similar to uniprot|P40339 Saccharomyces cerevisiae YOL094C RFC4 Subunit of heteropentameric Replication factor C (RF-C) which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon
similar to uniprot|P39904 Saccharomyces cerevisiae YDR484W
similar to uniprot|Q05379 Saccharomyces cerevisiae YOL095C HMI1 Mitochondrial inner membrane localized ATP-dependent DNA helicase required for the maintenance of the mitochondrial genome not required for mitochondrial transcription
similar to uniprot|Q03388 Saccharomyces cerevisiae YDR485C VPS72 Protein of unknown function component of the Swr1p complex that incorporates Htz1p into chromatin required for vacuolar protein sorting
similar to uniprot|P27680 Saccharomyces cerevisiae YOL096C
similar to uniprot|Q03390 Saccharomyces cerevisiae YDR486C VPS60 vacuolar protein sorting (putative)
highly similar to uniprot|Q12109 Saccharomyces cerevisiae YOL097C WRS1 Cytoplasmic tryptophanyl-tRNA synthetase aminoacylates tryptophanyl-tRNA
highly similar to uniprot|Q99258 Saccharomyces cerevisiae YDR487C RIB3 3 4-dihydroxy-2-butanone-4-phosphate synthase (DHBP synthase) required for riboflavin biosynthesis from ribulose-5-phosphate also has an unrelated function in mitochondrial respiration
weakly similar to uniprot|P40960 Saccharomyces cerevisiae YDR488C PAC11 Dynein intermediate chain acts in the cytoplasmic dynein pathway forms cortical cytoplasmic microtubule capture site with Num1p null mutant is defective in nuclear migration essential in the absence of CIN8
similar to uniprot|Q6Q558 Saccharomyces cerevisiae YDR489W SLD5 Subunit of the GINS complex (Sld5p Psf1p Psf2p Psf3p) which binds to DNA replication origins and facilitates assembly of the DNA replication machinery
similar to uniprot|Q12496 Saccharomyces cerevisiae YOL098C Hypothetical ORF
similar to uniprot|Q12236 YOL100W Saccharomyces cerevisiae YOL100W PKH2 Serine/threonine protein kinase involved in sphingolipid-mediated signaling pathway that controls endocytosis
similar to uniprot|Q6Q557 Saccharomyces cerevisiae YDR492W IZH1 Membrane protein involved in zinc metabolism member of the four-protein IZH family transcription is regulated directly by Zap1p expression induced by zinc deficiency and fatty acids deletion increases sensitivity to elevated zinc
similar to Q03429 YDR493W uniprot|Q03429 Saccharomyces cerevisiae FMP36
similar to uniprot|Q12272 YOL102C Saccharomyces cerevisiae TPT1 tRNA 2'-phosphotransferase
weakly similar to uniprot|Q8X185 Saccharomyces cerevisiae YDR494W RSM28 Mitochondrial ribosomal protein of the small subunit genetic interactions suggest a possible role in promoting translation initiation
similar to uniprot|P23643 Saccharomyces cerevisiae YDR495C VPS3 Vacuolar sorting protein
pumilio-family RNA binding domain-containing protein
similar to Q04373 YDR496C uniprot|Q04373 Saccharomyces cerevisiae PUF6 Pumilio-homology domain protein that binds ASH1 mRNA at PUF consensus sequences
similar to uniprot|P30606 Saccharomyces cerevisiae YOL103W ITR2 Myo-inositol transporter with strong similarity to the major myo-inositol transporter Itr1p, member of the sugar transporter superfamily; expressed constitutively and similar to YDR497C uniprot|P30605 Saccharomyces cerevisiae YDR497C ITR1 Myo-inositol transporter with strong similarity to the minor myo-inositol transporter Itr2p, member of the sugar transporter superfamily; expression is repressed by inositol and choline via Opi1p and derepressed via Ino2p and Ino4p
similar to uniprot|P28791 Saccharomyces cerevisiae YDR498C SEC20 Membrane glycoprotein v-SNARE involved in retrograde transport from the Golgi to the ER required for N- and O-glycosylation in the Golgi but not in the ER forms a complex with the cytosolic Tip20p
weakly similar to uniprot|Q12366 Saccharomyces cerevisiae YOL104C NDJ1 Meiosis-specific telomere protein required for bouquet formation effective homolog pairing ordered cross-over distributio (interference) sister chromatid cohesion at meiotic telomeres and segregation of small chromosomes
similar to uniprot|P32462 Saccharomyces cerevisiae YNL280C ERG24 C-14 sterol reductase acts in ergosterol biosynthesis mutants accumulate the abnormal sterol ignosterol (ergosta-8 14 dienol) and are viable under anaerobic growth conditions but inviable on rich medium under aerobic conditions
similar to uniprot|P53834 Saccharomyces cerevisiae YNL281W HCH1 Heat shock protein regulator that binds to Hsp90p and may stimulate ATPase activity originally identified as a high-copy number suppressor of a HSP90 loss-of-function mutation GFP-fusion protein localizes to the cytoplasm and nucleus
similar to uniprot|P53833 Saccharomyces cerevisiae YNL282W POP3 Subunit of both RNase MRP which cleaves pre-rRNA and nuclear RNase P which cleaves tRNA precursors to generate mature 5' ends
weakly similar to uniprot|P53832 Saccharomyces cerevisiae YNL283C WSC2 cell wall integrity and stress response component 2 Putative integral membrane protein containing novel cysteine motif. Similarity to SLG1 (WSC1) WSC3 and WSC4
mitochondrial 54S ribosomal protein YmL10/YmL18
similar to uniprot|P36520 Saccharomyces cerevisiae YNL284C MRPL10 Mitochondrial ribosomal protein of the large subunit appears as two protein spots (YmL10 and YmL18) on two-dimensional SDS gels
similar to uniprot|Q12239 Saccharomyces cerevisiae YOL107W Hypothetical ORF
some similarities with uniprot|P13902 Saccharomyces cerevisiae YOL108C INO4 Transcription factor required for derepression of inositol-choline-regulated genes involved in phospholipid synthesis forms a complex with Ino2p that binds the inositol-choline-responsive element through a basic helix-loop-helix domain
weakly similar to uniprot|P53830 Saccharomyces cerevisiae YNL286W CUS2 Protein that binds to U2 snRNA and Prp11p may be involved in U2 snRNA folding contains two RNA recognition motifs (RRMs)
highly similar to uniprot|P32074 Saccharomyces cerevisiae YNL287W SEC21 Gamma subunit of coatomer a heptameric protein complex that together with Arf1p forms the COPI coat involved in ER to Golgi transport of selective cargo
some similarities with uniprot|P36046 Saccharomyces cerevisiae YKL195W MIA40 Essential protein of the mitochondrial intermembrane space, involved in import and assembly of intermembrane space proteins
similar to uniprot|P53829 Saccharomyces cerevisiae YNL288W CAF40 Evolutionarily conserved subunit of the CCR4-NOT complex involved in controlling mRNA initiation elongation and degradation binds Cdc39p
similar to uniprot|Q07379 Saccharomyces cerevisiae YDL057W Hypothetical ORF
similar to uniprot|P39678 Saccharomyces cerevisiae YDL056W MBP1 Transcription factor involved in regulation of cell cycle progression from G1 to S phase forms a complex with Swi6p that binds to MluI cell cycle box regulatory element in promoters of DNA synthesis genes
highly similar to uniprot|P41940 Saccharomyces cerevisiae YDL055C PSA1 GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase) synthesizes GDP-mannose from GTP and mannose-1-phosphate in cell wall biosynthesis required for normal cell wall structure
highly similar to uniprot|P53045 Saccharomyces cerevisiae YGR060W ERG25 C-4 methyl sterol oxidase catalyzes the first of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis mutants accumulate the sterol intermediate 4 4-dimethylzymosterol
highly similar to uniprot|P32915 Saccharomyces cerevisiae YLR378C SEC61 Essential subunit of Sec61 complex (Sec61p Sbh1p and Sss1p) forms a channel for SRP- dependent protein import and retrograde transport of misfolded proteins out of the ER with Sec63 complex allows SRP-independent protein import into ER
similar to uniprot|Q07376 Saccharomyces cerevisiae YDL054C MCH1
some similarities with uniprot|Q07362 Saccharomyces cerevisiae YDL053C PBP4 Pbp1p binding protein
highly similar to uniprot|P09201 Saccharomyces cerevisiae YLR377C FBP1 Fructose-1 6-bisphosphatase key regulatory enzyme in the gluconeogenesis pathway required for glucose metabolism
similar to uniprot|P33333 Saccharomyces cerevisiae YDL052C SLC1 fatty acyltransferase
similar to uniprot|Q12318 Saccharomyces cerevisiae YLR376C
similar to uniprot|P33399 Saccharomyces cerevisiae YDL051W LHP1 RNA binding protein
similar to uniprot|P39005 Saccharomyces cerevisiae YJL174W KRE9 Glycoprotein involved in cell wall beta-glucan assembly; null mutation leads to severe growth defects, aberrant multibudded morphology, and mating defects
similar to uniprot|Q7LH06 Saccharomyces cerevisiae YDL048C STP4 Protein involved in pre-tRNA splicing and in uptake of branched-chain amino acids
similar to uniprot|P40319 Saccharomyces cerevisiae YLR372W SUR4 Elongase III synthesizes 20-26-carbon fatty acids from C18-CoA primers involved in fatty acid biosynthesis
similar to uniprot|P51862 Saccharomyces cerevisiae YLR371W ROM2 GDP/GTP exchange protein (GEP) for Rho1p and Rho2p mutations are synthetically lethal with mutations in rom1 which also encodes a GEP
highly similar to uniprot|Q05933 Saccharomyces cerevisiae YLR370C ARC18 Subunit of the ARP2/3 complex which is required for the motility and integrity of cortical actin patches
highly similar to uniprot|Q05931 Saccharomyces cerevisiae YLR369W SSQ1 Mitochondrial hsp70-type molecular chaperone involved in the synthesis and assembly of iron/sulfur clusters into proteins
weakly similar to uniprot|Q05930 Saccharomyces cerevisiae YLR368W MDM30 Protein involved in determination of mitochondrial structure
some similarities with uniprot|P53243 Saccharomyces cerevisiae YGR067C hypothetical ORF
highly similar to uniprot|Q3E7Y3 Saccharomyces cerevisiae YLR367W RPS22B and highly similar to uniprot|P0C0W1 Saccharomyces cerevisiae YJL190C RPS22A Proteins component of the small (40S) ribosomal subunit
highly similar to uniprot|P53241 Saccharomyces cerevisiae YGR065C VHT1 vitamin H transporter H -biotin symporter
similar to uniprot|Q05926 Saccharomyces cerevisiae YLR364W Hypothetical ORF
highly similar to uniprot|P32914 Saccharomyces cerevisiae YGR063C SPT4 Protein that forms a complex with Spt5p and mediates both activation and inhibition of transcription elongation and plays a role in pre-mRNA processing in addition Spt4p is involved in kinetochore function and gene silencing
similar to uniprot|P53239 Saccharomyces cerevisiae YGR062C
similar to uniprot|Q3E747 Saccharomyces cerevisiae YLR363W-A Hypothetical ORF
highly similar to uniprot|P38972 Saccharomyces cerevisiae YGR061C ADE6 Formylglycinamidine-ribonucleotide (FGAM)-synthetase catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway
similar to uniprot|Q12129 Saccharomyces cerevisiae YLR363C NMD4 Protein interacting with Nam7p may be involved in the nonsense-mediated mRNA decay pathway
similar to uniprot|P41901 Saccharomyces cerevisiae YGR059W SPR3 a sporulation-specific homologue of the yeast CDC3/10/11/12 family of bud neck microfilament genes regulated by ABFI septin protein involved in sporulation
some similarities with uniprot|P53238 Saccharomyces cerevisiae YGR058W Hypothetical ORF
similar to uniprot|P23561 Saccharomyces cerevisiae YLR362W STE11 Signal transducing MEK kinase involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p and the high osmolarity response pathway via phosphorylation of Pbs2p regulated by Ste20p and Ste50p
weakly similar to uniprot|Q05924 Saccharomyces cerevisia YLR361C-A Identified by expression profiling and mass spectrometry
similar to uniprot|Q05924 Saccharomyces cerevisiae YLR361C DCR2 Protein involved in cell cycle regulation
similar to uniprot|Q6B1J7 Saccharomyces cerevisiae YLR360W VPS38 involved in vacuolar protein targeting
similar to uniprot|P53237 Saccharomyces cerevisiae YGR057C LST7 Protein possibly involved in a post-Golgi secretory pathway required for the transport of nitrogen-regulated amino acid permease Gap1p from the Golgi to the cell surface
highly similar to uniprot|Q05911 Saccharomyces cerevisiae YLR359W ADE13 Adenylosuccinate lyase catalyzes two steps in the 'de novo' purine nucleotide biosynthetic pathway
similar to uniprot|Q06488 Saccharomyces cerevisiae YLR357W RSC2 One of 15 subunits of the 'Remodel the Structure of Chromatin' (RSC) complex required for expression of mid-late sporulation-specific genes contains two essential bromodomains a bromo-adjacent homology (BAH) domain and an AT hook
weakly similar to uniprot|P53685 Saccharomyces cerevisiae YOL068C HST1
similar to uniprot|P50276 Saccharomyces cerevisiae YGR055W MUP1 High affinity methionine permease integral membrane protein with 13 putative membrane-spanning regions also involved in cysteine uptake
similar to uniprot|P53235 Saccharomyces cerevisiae YGR054W yeast homolog of mammalian eIF2A
weakly similar to uniprot|P53234 Saccharomyces cerevisiae YGR053C Hypothetical ORF
similar to uniprot|Q45U35 Saccharomyces cerevisiae YGR049W
highly similar to uniprot|P06168 Saccharomyces cerevisiae YLR355C ILV5 Acetohydroxyacid reductoisomerase mitochondrial protein involved in branched-chain amino acid biosynthesis also required for maintenance of wild- type mitochondrial DNA
highly similar to uniprot|P16861 Saccharomyces cerevisiae YGR240C PFK1 Alpha subunit of heterooctameric phosphofructokinase involved in glycolysis indispensable for anaerobic growth activated by fructose-2 6-bisphosphate and AMP mutation inhibits glucose induction of cell cycle-related genes
some similarities with uniprot|P50091 Saccharomyces cerevisiae YGR239C PEX21 Part of a two-member peroxin family (Pex18p and Pex21p) specifically required for peroxisomal targeting of the Pex7p peroxisomal signal recognition factor and PTS2-type peroxisomal matrix proteins
some similarities with uniprot|P38854 Saccharomyces cerevisiae YHR159W Protein of unknown function that localizes to the cytoplasm potential Cdc28p substrate
similar to uniprot|Q75AR9 Ashbya gossypii ADL149W ADL149Wp and some similarites with YHR158C uniprot|P38853 Saccharomyces cerevisiae YHR158C KEL1 Protein required for proper cell fusion and cell morphology functions in a complex with Kel2p to negatively regulate mitotic exit interacts with Tem1p and Lte1p localizes to regions of polarized growth potential Cdc28p substrate
some similarities with uniprot|P50089 Saccharomyces cerevisiae YGR237C Hypothetical ORF
weakly similar to uniprot|P50088 Saccharomyces cerevisiae YGR236C SPG1 Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources
similar to uniprot|P81450 Saccharomyces cerevisiae YML081C-A ATP18 Subunit of the mitochondrial F1F0 ATP synthase
similar to uniprot|P47164 Saccharomyces cerevisiae YJR130C STR2 Cystathionine gamma-synthase converts cysteine into cystathionine
similar to uniprot|P32906 Saccharomyces cerevisiae YJR131W MNS1 Alpha-1 2-mannosidase involved in N-linked oligosaccharide biosynthesis catalyzes the removal of one mannose residue from Man9GlcNAc to produce a single isomer of Man8GlcNAc integral to the ER membrane
similar to uniprot|P38877 Saccharomyces cerevisiae YHR191C CTF8 Subunit of a complex with Ctf18p that shares some subunits with Replication Factor C and is required for sister chromatid cohesion
weakly similar to uniprot|P38878 Saccharomyces cerevisiae YHR192W Hypothetical ORF
similar to uniprot|P38879 Saccharomyces cerevisiae YHR193C EGD2 Alpha subunit of the heteromeric nascent polypeptide-associated complex (NAC) involved in protein sorting and translocation associated with cytoplasmic ribosomes
highly similar to uniprot|P38880 Saccharomyces cerevisiae YHR194W MDM31 Mitochondrial Distribution and Morphology
weakly similar to uniprot|P38881 Saccharomyces cerevisiae YHR195W NVJ1 Nuclear envelope protein that interacts with the vacuolar membrane protein Vac8p to promote formation of nucleus-vacuole junctions during piecemeal microautophagy of the nucleus (PMN)
similar to uniprot|P46970 Saccharomyces cerevisiae YJR132W NMD5 Karyopherin a carrier protein involved in nuclear import of proteins importin beta homolog
similar to uniprot|P38882 Saccharomyces cerevisiae YHR196W UTP9 Nucleolar protein component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
weakly similar to uniprot|P47166 Saccharomyces cerevisiae YJR134C SGM1 Protein of unknown function required for wild-type growth rate on galactose and mannose localizes to COPI coated vesicles and the Golgi apparatus
similar to uniprot|P38883 Saccharomyces cerevisiae YHR197W RIX1 RIbosome eXport essential protein
similar to uniprot|P47167 Saccharomyces cerevisiae YJR135C MCM22 Protein involved in minichromosome maintenance component of the kinetochore binds to centromeric DNA in a Ctf19p-dependent manner
highly similar to uniprot|P57744 Saccharomyces cerevisiae YJR135W-A TIM8 Mitochondrial intermembrane space import protein
similar to uniprot|P47168 Saccharomyces cerevisiae YJR136C Hypothetical ORF
similar to uniprot|P38884 Saccharomyces cerevisiae YHR198C FMP22 The authentic non-tagged protein was localized to the mitochondria
highly similar to uniprot|P47169 Saccharomyces cerevisiae YJR137C ECM17 Sulfite reductase beta subunit involved in amino acid biosynthesis transcription repressed by methionine
some similarities with uniprot|Q03661 Saccharomyces cerevisiae YMR219W ESC1 Protein localized to the nuclear periphery, involved in telomeric silencing; interacts with PAD4-domain of Sir4p
similar to uniprot|P38886 Saccharomyces cerevisiae YHR200W RPN10 Non-ATPase base subunit of the 19S regulatory particle of the 26S proteasome
similar to uniprot|P47170 Saccharomyces cerevisiae YJR138W IML1
highly similar to gnl|GLV|KLLA0B03872g Kluyveromyces lactis and similar to YJR139C uniprot|P31116 Saccharomyces cerevisiae HOM6 Homoserine dehydrogenase
similar to uniprot|P47171 Saccharomyces cerevisiae YJR140C HIR3 Transcriptional corepressor
similar to uniprot|P47172 Saccharomyces cerevisiae YJR141W Protein required for cell viability
similar to uniprot|P38698 Saccharomyces cerevisiae YHR201C PPX1 Exopolyphosphatase hydrolyzes inorganic polyphosphate (poly P) into Pi residues located in the cytosol plasma membrane and mitochondrial matrix
similar to uniprot|P47173 Saccharomyces cerevisiae YJR142W Hypothetical ORF
similar to uniprot|P46971 Saccharomyces cerevisiae YJR143C PMT4 Transfers mannose residues from dolichyl phosphate-D-mannose to specific serine/threonine residues of proteins in the secretory pathway dolichyl phosphate-D-mannose:protein O-D-mannosyltransferase
similar to uniprot|P32787 Saccharomyces cerevisiae YJR144W MGM101 Protein involved in mitochondrial genome maintenance component of the mitochondrial nucleoid required for the repair of oxidative mtDNA damage
similar to uniprot|P43606 Saccharomyces cerevisiae YFR029W PTR3 Component of the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p) which senses external amino acid concentration and transmits intracellular signals that result in regulation of expression of amino acid permease genes
similar to uniprot|P47051 Saccharomyces cerevisiae YJL046W Hypothetical ORF
similar to uniprot|P38336 Saccharomyces cerevisiae YBR257W POP4 Subunit of both RNase MRP which cleaves pre-rRNA and nuclear RNase P which cleaves tRNA precursors to generate mature 5' ends binds to the RPR1 RNA subunit in Rnase P
similar to uniprot|P38337 Saccharomyces cerevisiae YBR258C SHG1 Subunit of the COMPASS complex which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres
some similarities with uniprot|P38338 Saccharomyces cerevisiae YBR259W Hypothetical ORF
weakly similar to uniprot|P47050 Saccharomyces cerevisiae YJL047C RTT101 Cullin family member subunit of a complex containing ubiquitin ligase activity binds HRT1 and is modified by the ubiquitin like protein RUB1 Regulator of Ty1 Transposition Regulator of Ty1 Transposition
similar to uniprot|P38339 Saccharomyces cerevisiae YBR260C RGD1 GTPase-activating protein (RhoGAP) for Rho3p and Rho4p possibly involved in control of actin cytoskeleton organization
uniprot|Q9UVE4 Zygosaccharomyces rouxii Hypothetical protein highly similar to YBR261C uniprot|P38340 Saccharomyces cerevisiae YBR261C Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family
uniprot|Q9UVE5 Zygosaccharomyces rouxii Hypothetical protein similar to YBR262C uniprot|P38341 Saccharomyces cerevisiae YBR262C
highly similar to gnl|GLV|KLLA0F01210g Kluyveromyces lactis KLLA0F01210g and similar to YBR263W uniprot|P37292 Saccharomyces cerevisiae YBR263W SHM1 Serine hydroxymethyltransferase mitochondrial
similar to uniprot|P36019 Saccharomyces cerevisiae YNL093W YPT53 Involved in vacuolar protein sorting and endocytosis GTP-binding protein of the rab family
weakly similar to uniprot|P29539 Saccharomyces cerevisiae YBR275C RIF1 Protein that binds to the Rap1p C-terminus and acts synergistically with Rif2p to help control telomere length and establish telomeric silencing deletion results in telomere elongation
similar to uniprot|P38147 Saccharomyces cerevisiae YBR274W CHK1 checkpoint kinase 1
similar to uniprot|P38349 Saccharomyces cerevisiae YBR273C UBX7 UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p
similar to uniprot|P47048 Saccharomyces cerevisiae YJL049W Hypothetical ORF
highly similar to uniprot|P40335 Saccharomyces cerevisiae YJL053W PEP8 Vacuolar protein sorting protein that forms part of the multimeric membrane-associated retromer complex along with Vps35p Vps29p Vps17p and Vps5p essential for endosome-to-Golgi retrograde protein transport
weakly similar to uniprot|P47046 Saccharomyces cerevisiae YJL051W Protein of unknown function localized to the bud tip mRNA is targeted to the bud via the mRNA transport system involving She2p
highly similar to uniprot|P47047 Saccharomyces cerevisiae YJL050W MTR4 Dead-box family ATP dependent helicase required for mRNA export from the nucleus co-factor of the exosome complex required for 3' end formation of 5.8S rRNA
similar to uniprot|P38348 Saccharomyces cerevisiae YBR272C
highly similar to uniprot|P23542 Saccharomyces cerevisiae YLR027C AAT2 Cytosolic aspartate aminotransferase involved in nitrogen metabolism localizes to peroxisomes in oleate-grown cells
similar to uniprot|P50947 Saccharomyces cerevisiae YNL097C
similar to uniprot|P01120 Saccharomyces cerevisiae YNL098C RAS2 GTP-binding protein that regulates the nitrogen starvation response sporulation and filamentous growth farnesylation and palmitoylation required for activity and localization to plasma membrane homolog of mammalian Ras proto-oncogenes
similar to uniprot|P46964 Saccharomyces cerevisiae YOR103C OST2 Epsilon subunit of the oligosaccharyltransferase complex of the ER lumen which catalyzes asparagine-linked glycosylation of newly synthesized proteins
similar to uniprot|P50946 Saccharomyces cerevisiae YNL099C OCA1 Putative protein tyrosine phosphatase required for cell cycle arrest in response to oxidative damage of DNA
weakly similar to uniprot|Q12057 Saccharomyces cerevisiae YOR104W PIN2 Protein that induces appearance of [PIN ] prion when overproduced
weakly similar to uniprot|P50945 Saccharomyces cerevisiae YNL100W Hypothetical ORF
similar to uniprot|P50944 Saccharomyces cerevisiae YNL101W AVT4 Vacuolar transporter exports large neutral amino acids from the vacuole member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters
similar to uniprot|P13382 Saccharomyces cerevisiae YNL102W POL1 Catalytic subunit of the DNA polymerase alpha-primase complex required for the initiation of DNA replication during mitotic DNA synthesis and premeiotic DNA synthesis
similar to uniprot|Q12241 Saccharomyces cerevisiae YOR106W VAM3 Syntaxin-related protein required for vacuolar assembly PEP12 homolog
some similarities with uniprot|P32389 Saccharomyces cerevisiae YNL103W MET4 Lecine-zipper transcriptional activator responsible for the regulation of the sulfur amino acid pathway requires different combinations of the auxiliary factors Cbf1p Met28p Met31p and Met32p
some similarities with uniprot|Q99188 Saccharomyces cerevisiae YOR107W RGS2 Negative regulator of glucose-induced cAMP signaling directly activates the GTPase activity of the heterotrimeric G protein alpha subunit Gpa2p
highly similar to uniprot|P06208 Saccharomyces cerevisiae YNL104C LEU4 Alpha-isopropylmalate synthase (2-isopropylmalate synthase) the main isozyme responsible for the first step in the leucine biosynthesis pathway
similar to uniprot|Q12271 YOR109w Saccharomyces cerevisiae INP53 Phosphatidylinositol 4,5-bisphosphate 5-phosphatase
highly similar to uniprot|P53930 Saccharomyces cerevisiae YNL107W YAF9 Subunit of both the NuA4 histone H4 acetyltransferase complex and the SWR1 complex may function to antagonize silencing near telomeres interacts directly with Swc4p has homology to human leukemogenic protein AF9 contains a YEATS domain
similar to uniprot|Q6B220 Saccharomyces cerevisiae YOR110W
similar to uniprot|Q99210 Saccharomyces cerevisiae YOR111W Hypothetical ORF
similar to uniprot|P53927 Saccharomyces cerevisiae YNL110C NOP15 Constituent of 66S pre-ribosomal particles involved in 60S ribosomal subunit biogenesis localizes to both nucleolus and cytoplasm
similar to uniprot|P40312 Saccharomyces cerevisiae YNL111C CYB5 Cytochrome b5 involved in the sterol and lipid biosynthesis pathways required for sterol C5-6 and fatty acid desaturation
similar to uniprot|Q12453 Saccharomyces cerevisiae YOR112W Hypothetical ORF
similar to uniprot|P24783 Saccharomyces cerevisiae YNL112W DBP2 Essential ATP-dependent RNA helicase of the DEAD-box protein family involved in nonsense-mediated mRNA decay and rRNA processing
highly similar to uniprot|Q755Q7 Ashbya gossypii AFL220C AFL220Cp and similar to YNL113W uniprot|P28000 Saccharomyces cerevisiae YNL113W RPC19 RNA polymerase subunit common to RNA polymerases I and III
similar to uniprot|P36156 Saccharomyces cerevisiae YKR076W ECM4 Non-essential protein of unknown function gnl|GLV|KLLA0F12056g Kluyveromyces lactis
weakly similar to uniprot|P47084 Saccharomyces cerevisiae YJR003C Hypothetical ORF
highly similar to uniprot|Q92280 Saccharomyces cerevisiae YLR002C NOC3 Protein that forms a nuclear complex with Noc2p that binds to 66S ribosomal precursors to mediate their intranuclear transport also binds to chromatin to promote the association of DNA replication factors and replication initiation
similar to uniprot|P47083 Saccharomyces cerevisiae YJR002W
similar to uniprot|P47082 Saccharomyces cerevisiae YJR001W AVT1 Vacuolar transporter imports large neutral amino acids into the vacuole member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters
uniprot|Q96WU6 Zygosaccharomyces rouxii cr001 Hypothetical protein cr001-c
highly similar to uniprot|P54861 Saccharomyces cerevisiae YLL001W DNM1 Dynamin-related GTPase required for mitochondrial fission and the maintenance of mitochondrial morphology assembles on the cytoplasmic face of mitochondrial tubules at sites at which division will occur also participates in endocytosis
similar to uniprot|Q07794 Saccharomyces cerevisiae YLL002W RTT109 Regulator of Ty1 Transposition Regulation of mitochondrial network Killed in Mutagen sensitive to diepoxybutane and/or mitomycin C diepoxybutane and mitomycin C resistance
highly similar to uniprot|P38624 YJL001W Saccharomyces cerevisiae PRE3 20S proteasome beta-type subunit
similar to uniprot|Q12369 Saccharomyces cerevisiae YLL003W SFI1
similar to uniprot|P41543 Saccharomyces cerevisiae YJL002C OST1 Alpha subunit of the oligosaccharyltransferase complex of the ER lumen which catalyzes asparagine-linked glycosylation of newly synthesized proteins
highly similar to uniprot|P54790 Saccharomyces cerevisiae YLL004W ORC3 Subunit of the origin recognition complex which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing
highly similar to gnl|GLV|KLLA0F13024g Kluyveromyces lactis KLLA0F13024g and similar to YJL003W uniprot|P47081 Saccharomyces cerevisiae YJL003W COX16 Mitochondrial inner membrane protein required for assembly of cytochrome c oxidase
similar to uniprot|Q07798 Saccharomyces cerevisiae YLL005C SPO75 Meiosis-specific protein of unknown function required for spore wall formation during sporulation dispensable for both nuclear divisions during meiosis
similar to uniprot|P41800 Saccharomyces cerevisiae YLL006W MMM1 Mitochondrial outer membrane protein required for normal mitochondrial morphology and mtDNA stability involved in tethering mitochondria to the actin cytoskeleton and in anchoring mtDNA nucleoids
similar to uniprot|Q07799 Saccharomyces cerevisiae YLL007C Hypothetical ORF
similar to uniprot|P32892 Saccharomyces cerevisiae YLL008W DRS1 Nucleolar DEAD-box protein required for ribosome assembly and function including synthesis of 60S ribosomal subunits
highly similar to uniprot|P41544 Saccharomyces cerevisiae YJL004C SYS1 Multicopy suppressor of ypt6 null mutation
some similarities with uniprot|P08678 Saccharomyces cerevisiae YJL005W CYR1 Adenylate cyclase required for cAMP production and cAMP-dependent protein kinase signaling involved in cell cycle control and glucose and nitrogen repression of sporulation
highly similar to uniprot|Q07938 Saccharomyces cerevisiae YLR017W MEU1 Methylthioadenosine phosphorylase (MTAP) catalyzes the initial step in the methionine salvage pathway affects polyamine biosynthesis through regulation of ornithine decarboxylase (Spe1p) activity regulates ADH2 gene expression
similar to uniprot|Q7LGY6 Saccharomyces cerevisiae YLR018C POM34 nuclear pore integral membrane protein
similar to uniprot|Q07800 Saccharomyces cerevisiae YLL010C
highly similar to uniprot|P33750 Saccharomyces cerevisiae YLL011W
similar to uniprot|Q07950 Saccharomyces cerevisiae YLR020C YEH2 Steryl ester hydrolase catalyzes steryl ester hydrolysis at the plasma membrane involved in sterol metabolism
similar to uniprot|Q07951 Saccharomyces cerevisiae YLR021W Hypothetical ORF
highly similar to uniprot|Q07953 Saccharomyces cerevisiae YLR022C SDO1 Protein required for cell viability
some similarities with uniprot|Q07959 Saccharomyces cerevisiae YLR023C IZH3 Membrane protein involved in zinc metabolism member of the four-protein IZH family expression induced by zinc deficiency deletion reduces sensitivity to elevated zinc and shortens lag phase overexpression reduces Zap1p activity
some similarities with uniprot|Q02601 Saccharomyces cerevisiae YLL013C PUF3 member of the PUF protein family which is named for the founding members PUmilio and Fbf
similar to uniprot|Q12431 Saccharomyces cerevisiae YLL014W Hypothetical ORF
highly similar to uniprot|P48362 Saccharomyces cerevisiae YGR187C
similar to uniprot|P41895 Saccharomyces cerevisiae YGR186W TFG1 Largest subunit of the RNA Polymerase general transcription factor IIF (TFIIF) interacts with Fcp1p phosphatase and with TFIIB potentially phosphorylated by Cdc28p
highly similar to uniprot|P36421 Saccharomyces cerevisiae YGR185C TYS1 tyrosyl-tRNA synthetase cytoplasmic
similar to uniprot|Q07963 Saccharomyces cerevisiae YLR024C UBR2 Cytoplasmic ubiquitin-protein ligase (E3)
similar to uniprot|P19812 Saccharomyces cerevisiae YGR184C UBR1 Ubiquitin-protein ligase (E3) that interacts with Rad6p/Ubc2p to ubiquitinate substrates of the N-end rule pathway binds to the Rpn2p Rpt1p and Rpt6p proteins of the 19S particle of the 26S proteasome
similar to uniprot|P22289 Saccharomyces cerevisiae YGR183C QCR9 7.3 kDa subunit 9 of the ubiquinol cytochrome c oxidoreductase complex
highly similar to uniprot|P53299 Saccharomyces cerevisiae YGR181W TIM13 Translocase of the inner membrane mitochondrial intermembrane space protein mediating import and insertion of polytopic inner membrane proteins Subunit of mitochondrial protein import machinery
highly similar to uniprot|P47064 Saccharomyces cerevisiae YJL024C APS3 Small subunit of the clathrin-associated adaptor complex AP-3 which is involved in vacuolar protein sorting related to the sigma subunit of the mammalian clathrin AP-3 complex suppressor of loss of casein kinase 1 function
highly similar to gnl|GLV|KLLA0F15246g Kluyveromyces lactis KLLA0F15246g and similar to YGR174C uniprot|P37267 Saccharomyces cerevisiae YGR174C CBP4 Essential for the expression and activity of ubiquinol- cytochrome c reductase ubiquinol--cytochrome-c reductase assembly factor
highly similar to uniprot|P32476 Saccharomyces cerevisiae YGR175C ERG1 Squalene epoxidase catalyzes the epoxidation of squalene to 2 3-oxidosqualene plays an essential role in the ergosterol-biosynthesis pathway and is the specific target of the antifungal drug terbinafine
similar to uniprot|P40992 Saccharomyces cerevisiae YJL025W RRN7 involved in the transcription of 35S rRNA genes by RNA polymerase I member of yeast Pol I core factor (CF) also composed of Rrn11p Rrn6p and TATA-binding protein
similar to uniprot|P53297 Saccharomyces cerevisiae YGR178C PBP1 Protein interacting with poly(A)-binding protein Pab1p likely involved in control of the extent of mRNA polyadenylation
weakly similar to uniprot|P53298 Saccharomyces cerevisiae YGR179C OKP1 Outer kinetochore protein required for accurate mitotic chromosome segregation forms a complex with Mcm21p and Okp1p that binds to centromeres via the CBF3 complex
similar to uniprot|Q01477 Saccharomyces cerevisiae YER151C UBP3 Ubiquitin-specific protease that interacts with Bre5p to co-regulate anterograde and retrograde transport between endoplasmic reticulum and Golgi compartments inhibitor of gene silencing cleaves ubiquitin fusions but not polyubiquitin
similar to uniprot|P38957 Saccharomyces cerevisiae YDR078C SHU2 Suppressor of hydroxy-urea sensitivity
similar to uniprot|P10356 Saccharomyces cerevisiae YER152C Hypothetical ORF
similar to uniprot|O13377 Saccharomyces kluyveri PET122 Protein PET122 mitochondrial precursor and weakly similar to YER153C uniprot|P10355 Saccharomyces cerevisiae YER153C PET122 Specific translational activator for the COX3 mRNA that acts together with Pet54p and Pet494p located in the mitochondrial inner membrane
similar to uniprot|P39952 Saccharomyces cerevisiae YER154W OXA1 Translocase of the mitochondrial inner membrane mediates the insertion of both mitochondrial- and nuclear-encoded proteins from the matrix into the inner membrane interacts with mitochondrial ribosomes null is respiratory deficient
similar to uniprot|P39960 Saccharomyces cerevisiae YER155C BEM2 Rho GTPase activating protein (RhoGAP) involved in the control of cytoskeleton organization and cellular morphogenesis required for bud emergence
similar to uniprot|P40093 Saccharomyces cerevisiae YER156C Hypothetical ORF
similar to uniprot|P38958 Saccharomyces cerevisiae YDR079W PET100 Chaperone that specifically facilitates the assembly of cytochrome c oxidase located in the mitochondrial inner membrane
similar to uniprot|P40094 Saccharomyces cerevisiae YER157W COG3 Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog8p) a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
highly similar to uniprot|Q3E7C1 Saccharomyces cerevisiae YDR079C-A TFB5 Component of the RNA polymerase II general transcription and DNA repair factor TFIIH involved in transcription initiation homolog of the Chlamydomonas reinhardtii REX1-S protein which is involved in DNA repair
similar to uniprot|P38959 Saccharomyces cerevisiae YDR080W VPS41 vacuolar protein sorting component of vacuolar membrane protein complex
similar to uniprot|P32896 Saccharomyces cerevisiae YDR081C PDC2 Transcription factor required for the synthesis of the glycolytic enzyme pyruvate decarboxylase required for high level expression of both the THI and the PDC genes
some similarities with uniprot|P38960 Saccharomyces cerevisiae YDR082W STN1 Protein involved in telomere length regulation functions in telomere metabolism during late S phase
similar to uniprot|P38961 Saccharomyces cerevisiae YDR083W RRP8
similar to uniprot|P38962 Saccharomyces cerevisiae YDR084C TVP23 Integral membrane protein localized to vesicles along with the v-SNARE Tlg2p green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
some similarities with uniprot|P33304 Saccharomyces cerevisiae YDR085C
similar to uniprot|P40096 Saccharomyces cerevisiae YER159C BUR6 Protein that forms a heterodimeric histone-fold NC2 general transcription regulator complex with Ydr1p that binds to TBP and represses RNA pol II transcription during assembly of the preinitiation complex homologous to human NC2alpha
similar to uniprot|P35179 Saccharomyces cerevisiae YDR086C SSS1 Subunit of the Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p) involved in transfer of secretory precursors through the endoplasmic reticulum membrane endoplasmic reticulum protein that is part of the Sec61 trimeric complex and the Ssh1 trimeric complex
similar to uniprot|P35178 Saccharomyces cerevisiae YDR087C RRP1 involved in processing rRNA precursor species to mature rRNAs involved in rRNA processing
similar to uniprot|Q02775 Saccharomyces cerevisiae YDR088C SLU7 Protein involved in 3' splice site choices acts in concert with Prp18p during the 2nd step of splicing
weakly similar to uniprot|P06843 Saccharomyces cerevisiae YER161c SPT2 multifunctional HMG-like chromatin protein
similar to uniprot|P14736 Saccharomyces cerevisiae YER162C RAD4 Protein that recognizes and binds damaged DNA (with Rad23p) during nucleotide excision repair subunit of Nuclear Excision Repair Factor 2 (NEF2) homolog of human XPC protein
similar to uniprot|P32656 Saccharomyces cerevisiae YER163C Hypothetical ORF
highly similar to uniprot|Q03195 Saccharomyces cerevisiae YDR091C RLI1 Predicted ABC family ATPase required for translation initiation facilitates binding of a multifactor complex (MFC) of translation initiation factors to the small ribosomal subunit may have a role in large ribosomal subunit biogenesis
similar to uniprot|P32657 Saccharomyces cerevisiae YER164W CHD1 Sole S. cerevisiae member of CHD gene family containing Chromodomain Helicase domain and DNA-binding domain transcriptional regulator
highly similar to uniprot|P04147 Saccharomyces cerevisiae YER165W PAB1 Poly(A) binding protein part of the 3'-end RNA-processing complex mediates interactions between the 5' cap structure and the 3' mRNA poly(A) tail involved in control of poly(A) tail length interacts with translation factor eIF-4G
highly similar to uniprot|P52490 Saccharomyces cerevisiae YDR092W UBC13 Ubiquitin-conjugating enzyme involved in the error-free DNA postreplication repair pathway interacts with Mms2p to assemble ubiquitin chains at the Ub Lys-63 residue DNA damage triggers redistribution from the cytoplasm to the nucleus
highly similar to uniprot|P32660 Saccharomyces cerevisiae YER166W DNF1 Non-essential P-type ATPase that is a potential aminophospholipid translocase localizes to the plasma membrane and late exocytic or early endocytic membranes likely involved in protein transport
weakly similar to uniprot|P33306 Saccharomyces cerevisiae YER167W BCK2 Protein rich in serine and threonine residues involved in protein kinase C signaling pathway which controls cell integrity overproduction suppresses pkc1 mutations
similar to uniprot|P21269 Saccharomyces cerevisiae YER168C CCA1 tRNA nucleotidyltransferase (tRNA CCA-pyrophosphorylase)
similar to uniprot|P39956 Saccharomyces cerevisiae YER169W RPH1 Transcriptional repressor of PHR1 which is a photolyase induced by DNA damage binds to AG(4) (C(4)T) sequence upstream of PHR1 Rph1p phosphorylation during DNA damage is under control of the MEC1-RAD53 pathway
similar to uniprot|Q03834 Saccharomyces cerevisiae YDR097C MSH6 Protein required for mismatch repair in mitosis and meiosis forms a complex with Msh2p to repair both single-base & insertion-deletion mispairs potentially phosphorylated by Cdc28p
similar to uniprot|P26364 Saccharomyces cerevisiae YER170W ADK2 Mitochondrial adenylate kinase catalyzes the reversible synthesis of GTP and AMP from GDP and ADP may serve as a back-up for synthesizing GTP or ADP depending on metabolic conditions 3' sequence of ADK2 varies with strain background
highly similar to uniprot|P06839 Saccharomyces cerevisiae YER171W RAD3 5' to 3' DNA helicase involved in nucleotide excision repair and transcription subunit of RNA polymerase II transcription initiation factor TFIIH subunit of Nucleotide Excision Repair Factor 3 (NEF3) homolog of human XPD protein
similar to uniprot|P32639 Saccharomyces cerevisiae YER172C BRR2 RNA-dependent ATPase RNA helicase involved in the facilitation and disruption of snRNA interactions required for disruption of U4/U6 base-pairing in native snRNPs to activate the spliceosome for catalysis
similar to uniprot|P32641 Saccharomyces cerevisiae YER173W RAD24 Checkpoint protein involved in the activation of the DNA damage and meiotic pachytene checkpoints subunit of a clamp loader that loads Rad17p- Mec3p-Ddc1p onto DNA homolog of human and S. pombe Rad17 protein
similar to uniprot|Q03835 Saccharomyces cerevisiae YDR098C GRX3 Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase monothiol glutaredoxin subfamily member along with Grx4p and Grx5p protects cells from oxidative damage
similar to uniprot|P32643 Saccharomyces cerevisiae YER175C TMT1 Trans-aconitate methyltransferase
similar to uniprot|P32644 Saccharomyces cerevisiae YER176W ECM32 DNA dependent ATPase/DNA helicase belonging to the Dna2p- and Nam7p-like family of helicases that is involved in modulating translation termination interacts with the translation termination factors localized to polysomes
highly similar to uniprot|Q74ZU1 Ashbya gossypii AGR107C AGR107Cp and similar to YDR099W uniprot|P34730 Saccharomyces cerevisiae YDR099W BMH2 14-3-3 protein minor isoform binds proteins and DNA involved in regulation of many processes including exocytosis and vesicle transport Ras/MAPK signaling during pseudohyphal development rapamycin- sensitive signaling and others
similar to uniprot|Q03860 Saccharomyces cerevisiae YDR100W TVP15 Tlg2-Vesicle Protein of 15 kDa integral membrane vesicle protein
similar to uniprot|Q03862 Saccharomyces cerevisiae YDR101C ARX1 Protein associated with the ribosomal export complex
similar to uniprot|Q6B265 Saccharomyces cerevisiae YLR380W CSR1 Phosphatidylinositol transfer protein with a potential role in lipid turnover interacts specifically with thioredoxin peroxidase (Tsa2p) and may have a role in oxidative stress resistance
similar to uniprot|Q7LHY6 Saccharomyces cerevisiae YLR381W CTF3 Outer kinetochore protein that forms a complex with Mcm16p and Mcm22p may bind the kinetochore to spindle microtubules
similar to uniprot|P11325 Saccharomyces cerevisiae YLR382C NAM2 Mitochondrial leucyl-tRNA synthetase also has a direct role in splicing of several mitochondrial group I introns indirectly required for mitochondrial genome maintenance
similar to uniprot|Q12749 Saccharomyces cerevisiae YLR383W RHC18 Protein involved in structural maintenance of chromosomes required for interchromosomal and sister chromatid recombination
similar to uniprot|P25386 Saccharomyces cerevisiae YDL058W USO1 involved intracellular protein transport coiled-coil protein necessary for protein transport from ER to Golgi Integrin analogue gene
similar to uniprot|Q12223 Saccharomyces cerevisiae YDL059C RAD59 Protein involved in the repair of double-strand breaks in DNA during vegetative growth via recombination and single-strand annealing anneals complementary single-stranded DNA homologous to Rad52p
similar to uniprot|Q06706 Saccharomyces cerevisiae YLR384C IKI3 Subunit of RNA polymerase II elongator complex which is a histone acetyltransferase involved in maintaining structural integrity of the complex iki3 mutations confer resistance to the K. lactis toxin zymocin
similar to uniprot|Q06707 Saccharomyces cerevisiae YLR385C SWC7
similar to uniprot|Q06708 Saccharomyces cerevisiae YLR386W VAC14 Activator of Fab1p
similar to uniprot|Q7LIF0 Saccharomyces cerevisiae YLR387C REH1 Protein of unknown function, similar to Rei1p but not involved in bud growth
similar to gnl|GLV|DEHA0A12001g Debaryomyces hansenii DEHA0A12001g and weakly similar with YDL060W uniprot|Q03128 Saccharomyces cerevisiae YDL060W TSR1 Protein required for processing of 20S pre-rRNA in the cytoplasm associates with pre-40S ribosomal particles
highly similar to uniprot|P41058 Saccharomyces cerevisiae YDL061C or to YLR388W uniprot|P41057 Saccharomyces cerevisiae YLR388W
similar to uniprot|Q06010 Saccharomyces cerevisiae YLR389C STE23 Metalloprotease involved with homolog Axl1p in N-terminal processing of pro-a-factor to the mature form member of the insulin-degrading enzyme family
similar to uniprot|Q7LGT0 Saccharomyces cerevisiae YDL063C
highly similar to uniprot|P50623 Saccharomyces cerevisiae YDL064W UBC9 SUMO-conjugating enzyme involved in the Smt3p conjugation pathway nuclear protein required for S- and M-phase cyclin degradation and mitotic control involved in proteolysis mediated by the anaphase-promoting complex cyclosome (APCC)
similar to uniprot|Q07418 Saccharomyces cerevisiae YDL065C PEX19 Chaperone and import receptor for newly-synthesized class I peroxisomal membrane proteins
some similarities with uniprot|O13547 Saccharomyces cerevisiae YLR390W-A CCW14 Secretory Stress Response protein
similar to uniprot|P18634 Saccharomyces cerevisiae YLR392C Hypothetical ORF
similar to uniprot|P18496 Saccharomyces cerevisiae YLR393W ATP10 Mitochondrial inner membrane protein required for assembly of the F0 sector of mitochondrial F1F0 ATP synthase interacts genetically with ATP6
highly similar to uniprot|P21954 Saccharomyces cerevisiae YDL066W IDP1 Mitochondrial NADP-specific isocitrate dehydrogenase catalyzes the oxidation of isocitrate to alpha-ketoglutarate not required for mitochondrial respiration and may function to divert alpha-ketoglutarate to biosynthetic processes
similar to gnl|GLV|KLLA0B03333g Kluyveromyces lactis KLLA0B03333g and some similarites with YLR394W uniprot|Q06032 Saccharomyces cerevisiae YLR394W CST9 Protein required for synaptonemal complex formation may have a role in meiotic recombination localizes to synapsis initiation sites on meiotic chromosomes potential Cdc28p substrate
similar to uniprot|P04039 Saccharomyces cerevisiae YLR395C COX8 Subunit VIII of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain
similar to uniprot|P07255 Saccharomyces cerevisiae YDL067C COX9
similar to uniprot|P20795 Saccharomyces cerevisiae YLR396C VPS33 vacuolar sorting protein essential for vacuolar morphogenesis and function involved in vacuolar protein targeting
highly similar to uniprot|P32794 Saccharomyces cerevisiae YLR397C AFG2 ATPase of the CDC48/PAS1/SEC18 (AAA) family forms a hexameric complex may be involved in degradation of aberrant mRNAs
weakly similar to uniprot|P14066 Saccharomyces cerevisiae YDL069C
similar to uniprot|P35207 Saccharomyces cerevisiae YLR398C SKI2 blocks translation of non-poly(A) mRNAs antiviral protein putative helicase
similar to uniprot|P35817 Saccharomyces cerevisiae YLR399C BDF1 Protein involved in transcription initiation at TATA-containing promoters associates with the basal transcription factor TFIID contains two bromodomains corresponds to the C-terminal region of mammalian TAF1 redundant with Bdf2p
similar to uniprot|Q7LGS8 Saccharomyces cerevisiae YDL072C YET3 Endoplasmic reticulum transmembrane protein homolog of human BAP31 protein
similar to uniprot|Q06053 Saccharomyces cerevisiae YLR401C DUS3 Dihydrouridine synthase member of a widespread family of conserved proteins including Smm1p Dus1p and Dus4p contains a consensus oleate response element (ORE) in its promoter region
some similarities with uniprot|P32432 Saccharomyces cerevisiae YLR403W SFP1 Transcription factor that integrates information from nutrient- and stress-responsive signaling pathways to help control ribosomal protein gene expression inhibits nuclear protein localization when present in multiple copies
similar to uniprot|Q06058 Saccharomyces cerevisiae YLR404W Hypothetical ORF
weakly similar to uniprot|Q07454 Saccharomyces cerevisiae YDL073W Hypothetical ORF
similar to uniprot|Q07457 Saccharomyces cerevisiae YDL074C BRE1 E3 ubiquitin ligase for Rad6p required for the ubiquitination of histone H2B recruitment of Rad6p to promoter chromatin and subsequent methylation of histone H3 (on L4 and L79) contains RING finger domain
similar to uniprot|Q06063 Saccharomyces cerevisiae YLR405W DUS4 Dihydrouridine synthase member of a widespread family of conserved proteins including Smm1p Dus1p and Dus3p
highly similar to uniprot|P04649 Saccharomyces cerevisiae YDL075W RPL31A and to YLR406C uniprot|P04649 Saccharomyces cerevisiae YLR406C RPL31B, Protein component of the large (60S) ribosomal subunit
similar to uniprot|Q07458 Saccharomyces cerevisiae YDL076C RXT3 Hypothetical ORF
similar to uniprot|Q06070 Saccharomyces cerevisiae YLR407W Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
similar to uniprot|Q06071 Saccharomyces cerevisiae YLR408C Hypothetical ORF
similar to uniprot|Q07468 Saccharomyces cerevisiae YDL077C VAM6 Protein involved in vacuolar morphogenesis
highly similar to uniprot|Q06078 Saccharomyces cerevisiae YLR409C UTP21 Possible U3 snoRNP protein involved in maturation of pre-18S rRNA based on computational analysis of large-scale protein-protein interaction data
highly similar to uniprot|Q06685 Saccharomyces cerevisiae YLR410W VIP1
highly similar to uniprot|P32895 Saccharomyces cerevisiae YKL181W PRS1 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase involved in nucleotide histidine and tryptophan biosynthesis one of five related enzymes which are active as heteromultimeric complexes
similar to uniprot|Q06688 Saccharomyces cerevisiae YLR412W Hypothetical ORF
highly similar to uniprot|P07149 Saccharomyces cerevisiae YKL182W FAS1 Beta subunit of fatty acid synthetase which catalyzes the synthesis of long-chain saturated fatty acids contains acetyltransacylase dehydratase enoyl reductase malonyl transacylase and palmitoyl transacylase activities
similar to uniprot|P34234 Saccharomyces cerevisiae YKL183W LOT5 Protein of unknown function gene expression increases in cultures shifted to a lower temperature
similar to uniprot|P08432 Saccharomyces cerevisiae YKL184W SPE1 Rate limiting step of polyamine biosynthesis pathway Ornithine decarboxylase
weakly similar to uniprot|P34233 Saccharomyces cerevisiae YKL185W ASH1 Zinc-finger inhibitor of HO transcription mRNA is localized and translated in the distal tip of anaphase cells resulting in accumulation of Ash1p in daughter cell nuclei and inhibition of HO expression potential Cdc28p substrate
similar to uniprot|P34232 Saccharomyces cerevisiae YKL186C MTR2 mRNA transport regulator essential nuclear protein Mex67p and Mtr2p form a mRNA export complex which binds to RNA
similar to uniprot|Q6B322 Saccharomyces cerevisiae YLR414C Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cell periphery cytoplasm and bud
similar to uniprot|P34230 Saccharomyces cerevisiae YKL188C PXA2 Homolog of the human adrenoleukodystrophy transporter forms a heterodimer with Pxa1p of two half ATP-binding cassette transporters in the peroxisome membrane peroxisomal ABC transporter 2
similar to uniprot|Q06696 Saccharomyces cerevisiae YLR417W VPS36 Component of the ESCRT-II complex which is involved in ubiquitin-dependent sorting of proteins into the endosome
similar to uniprot|P32464 Saccharomyces cerevisiae YKL189W HYM1 Component of the RAM signaling network that is involved in regulation of Ace2p activity and cellular morphogenesis interacts with Kic1p and Sog2p localizes to sites of polarized growth during budding and during the mating response
similar to uniprot|Q06697 Saccharomyces cerevisiae YLR418C CDC73 Substituent of the Paf1 complex together with RNA polymerase II Paf1p Hpr1p Ctr9 Leo1 Rtf1 and Ccr4p distinct from Srb-containing Pol II complexes required for the expression of certain genes and modification of some histones
similar to uniprot|Q06698 Saccharomyces cerevisiae YLR419W Hypothetical ORF
similar to gnl|GLV|YALI0E26719g Yarrowia lipolytica YALI0E26719g uniprot|Q12724 disrupted by Saccharomyces cerevisiae Invertase 2 precursor identified start YALI0E26719g|YALI-IPF3380|YALI-CDS1951.1 and weakly similar to YIL162W uniprot|P00724 Saccharomyces cerevisiae YIL162W SUC2
similar to uniprot|P15365 Saccharomyces cerevisiae YJR152W DAL5 Allantoin permease ureidosuccinate permease expression is constitutive but sensitive to nitrogen catabolite repression
highly similar to uniprot|P25296 Saccharomyces cerevisiae YKL190W CNB1 Type 2B protein phosphatase
similar to uniprot|P32461 Saccharomyces cerevisiae YKL191W DPH2 Protein required along with Dph1p Kti11p Jjj3p and Dph5p for synthesis of diphthamide which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p) may act in a complex with Dph1p and Kti11p
highly similar to uniprot|P20051 Saccharomyces cerevisiae YLR420W URA4 Third step in pyrimidine biosynthesis pathway dihydrooratase
similar to uniprot|O13563 Saccharomyces cerevisiae YLR421C RPN13 Subunit of the 19S regulatory particle of the 26S proteasome lid
similar to uniprot|Q06409 Saccharomyces cerevisiae YLR422W Hypothetical ORF
similar to uniprot|P32463 Saccharomyces cerevisiae YKL192C ACP1 Mitochondrial matrix acyl carrier protein involved in biosynthesis of octanoate which is a precursor to lipoic acid activated by phosphopantetheinylation catalyzed by Ppt2p
similar to uniprot|P36047 Saccharomyces cerevisiae YKL193C SDS22 Regulatory subunit of Glc7p type1 protein phosphatase
highly similar to gnl|GLV|KLLA0D02772g Kluyveromyces lactis KLLA0D02772g and similar to YKL194C uniprot|P07236 Saccharomyces cerevisiae YKL194C MST1 Mitochondrial threonyl-tRNA synthetase
similar to uniprot|Q06410 Saccharomyces cerevisiae YLR423C ATG17 Protein that interacts with and is required for activation of Apg1p protein kinase involved in autophagy but not in the Cvt (cytoplasm to vacuole targeting) pathway
weakly similar to uniprot|Q06411 Saccharomyces cerevisiae YLR424W SPP382 Essential protein present in native splicing complexes identified as a suppressor of prp38-1 a spliceosomal maturation mutation cold sensitive alleles accumulate pre-mRNA
some similarities with uniprot|P36046 Saccharomyces cerevisiae YKL195W MIA40 Essential protein of the mitochondrial intermembrane space involved in import and assembly of intermembrane space proteins
highly similar to uniprot|P36015 Saccharomyces cerevisiae YKL196C YKT6 v-SNARE (synaptobrevin) essential for endoplasmic reticulum-Golgi transport
similar to uniprot|P00175 Saccharomyces cerevisiae YML054C CYB2 Cytochrome b2 (L-lactate cytochrome-c oxidoreductase) component of the mitochondrial intermembrane space required for lactate utilization expression is repressed by glucose and anaerobic conditions
similar to uniprot|Q06412 Saccharomyces cerevisiae YLR425W TUS1 Guanine nucleotide exchange factor (GEF) that functions to modulate Rhop1 activity as part of the cell integrity signaling pathway multicopy suppressor of tor2 mutation and ypk1 ypk2 double mutation potential Cdc28p substrate
similar to uniprot|Q06417 Saccharomyces cerevisiae YLR426W Hypothetical ORF
similar to uniprot|Q04969 Saccharomyces cerevisiae YML055W SPC2 Subunit of signal peptidase complex (Spc1p Spc2p Spc3p Sec11p) which catalyzes cleavage of N-terminal signal sequences of proteins targeted to the secretory pathway homologous to mammalian SPC25
similar to uniprot|Q06436 Saccharomyces cerevisiae YLR427W MAG2 DNA-3-methyladenine glycosidase II that catalyzes of the hydrolysis of alkylated DNA
some similarities with uniprot|Q06440 Saccharomyces cerevisiae YLR429W CRN1 Coronin cortical actin cytoskeletal component that associates with the Arp2p/Arp3p complex to regulate its activity
similar to uniprot|Q00416 Saccharomyces cerevisiae YLR430W SEN1 Nuclear protein putative helicase required for processing of tRNAs rRNAs and small nuclear RNAs potential Cdc28p substrate
similar to uniprot|Q06671 Saccharomyces cerevisiae YLR431C ATG23 Peripheral membrane protein required for autophagy and for the cytoplasm-to-vacuole targeting (Cvt) pathway
highly similar to uniprot|P50094 Saccharomyces cerevisiae IMD4 and to YLR432W uniprot|P50095 Saccharomyces cerevisiae IMD3 and to YHR216W uniprot|P38697 Saccharomyces cerevisiae IMD2, Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, expression is induced by mycophenolic acid resulting in resistance to the drug, expression is repressed by nutrient limitation
similar to uniprot|P14747 Saccharomyces cerevisiae YML057W CMP2 calmodulin binding protein and to YLR433C uniprot|P23287 Saccharomyces cerevisiae YLR433C CNA1 calmodulin binding protein
similar to uniprot|Q06672 Saccharomyces cerevisiae YLR435W TSR2 Protein with a potential role in pre-rRNA processing
some similarities with uniprot|Q06673 Saccharomyces cerevisiae YLR436C ECM30 Non-essential protein of unknown function
weakly similar to uniprot|O13577 Saccharomyces cerevisiae YLR437C Hypothetical ORF
highly similar to uniprot|P07991 Saccharomyces cerevisiae YLR438W CAR2 L-ornithine transaminase (OTAse) catalyzes the second step of arginine degradation expression is dually-regulated by allophanate induction and a specific arginine induction process not nitrogen catabolite repression sensitive
similar to uniprot|Q04958 Saccharomyces cerevisiae YML059C NTE1 Serine esterase that deacylates exogenous lysophospholipids homolog of human neuropathy target esterase (NTE) mammalian NTE1 deacylates phosphatidylcholine to glycerophosphocholine
similar to uniprot|P57743 Saccharomyces cerevisiae YLR438C-A LSM3 Component of small nuclear ribonucleoprotein complexes involved in RNA processing splicing and decay
mitochondrial 54S ribosomal protein YmL4
similar to uniprot|P36517 Saccharomyces cerevisiae YLR439W MRPL4 Mitochondrial ribosomal protein of the large subunit
similar to uniprot|P53397 Saccharomyces cerevisiae YML060W OGG1 Mitochondrial glycosylase/lyase that specifically excises 7 8-dihydro-8-oxoguanine residues located opposite cytosine or thymine residues in DNA repairs oxidative damage to mitochondrial DNA
similar to uniprot|P07271 Saccharomyces cerevisiae YML061C PIF1 DNA helicase involved in telomere formation and elongation acts as a catalytic inhibitor of telomerase also plays a role in repair and recombination of mitochondrial DNA
similar to uniprot|Q7LHI0 Saccharomyces cerevisiae YLR440C SEC39 Protein of unknown function proposed to be involved in protein secretion
some similarities with uniprot|P33441 Saccharomyces cerevisiae YML062C MFT1 Subunit of the THO complex which is a nuclear complex comprised of Hpr1p Mft1p Rlr1p and Thp2p that is involved in transcription elongation and mitotic recombination
highly similar to uniprot|P23248 Saccharomyces cerevisiae RPS1B and uniprot|P33442 Saccharomyces cerevisiae YLR441C RPS1A Ribosomal protein 10 (rp10) of the small (40S) subunit
similar to uniprot|P38987 Saccharomyces cerevisiae YML064C TEM1 Gtp-binding protein of the ras superfamily involved in termination of M-phase GTP-binding protein RAS superfamily
similar to uniprot|P54784 Saccharomyces cerevisiae YML065W ORC1 Largest subunit of the origin recognition complex which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing may be phosphorylated by Cdc28p
similar to uniprot|Q2VQX1 Saccharomyces cerevisiae YLR443W ECM7 Non-essential protein of unknown function
similar to uniprot|Q04658 Saccharomyces cerevisiae YML066C SMA2 Spore Membrane Assembly
similar to uniprot|Q04651 Saccharomyces cerevisiae YML067C ERV41 Protein in COPII-coated vesicles
similar to uniprot|Q06201 Saccharomyces cerevisiae YLR445W
similar to uniprot|Q04638 Saccharomyces cerevisiae YML068W ITT1 Protein that modulates the efficiency of translation termination interacts with translation release factors eRF1 (Sup45p) and eRF3 (Sup35p) in vitro contains a zinc finger domain characteristic of the TRIAD class of proteins
highly similar to uniprot|Q04636 Saccharomyces cerevisiae YML069W POB3 facilitates RNA Polymerase II transcription elongation
uniprot|Q9HFC5 Zygosaccharomyces rouxii dak1 Dihydroxyacetone kinase
some similarities with uniprot|P39743 Saccharomyces cerevisiae YDR388W RVS167 BAR adaptor protein, subunit of a complex (Rvs161p-Rvs167p) that regulates actin, endocytosis, and viability following starvation or osmotic stress
similar to uniprot|Q6B2U1 Saccharomyces cerevisiae YLR446W Hypothetical ORF
some similarities with uniprot|Q12091 Saccharomyces cerevisiae YPL170W DAP1 Heme-binding protein involved in regulation of cytochrome P450 protein Erg11p; damage response protein, related to mammalian membrane progesterone receptors; mutations lead to defects in telomeres, mitochondria, and sterol synthesis
highly similar to uniprot|P32366 Saccharomyces cerevisiae YLR447C VMA6 vacuolar ATPase V0 domain subunit d
similar to uniprot|Q04632 Saccharomyces cerevisiae YML071C COG8 Component of the conserved oligomeric Golgi complex
similar to uniprot|Q03640 Saccharomyces cerevisiae YML072C TCB3 Contains three calcium and lipid binding domains localized to the bud green fluorescent protein (GFP)-fusion protein localizes to the cell periphery mRNA is targeted to the bud via the mRNA transport system involving She2p C-terminal portion of Tcb1p Tcb2p and Tcb3p interact
highly similar to uniprot|P05739 Saccharomyces cerevisiae YLR448W
highly similar to uniprot|Q06205 Saccharomyces cerevisiae and to YML074c uniprot|P38911 Saccharomyces cerevisiae
similar to uniprot|P12683 Saccharomyces cerevisiae YML075C HMG1 One of two isozymes of HMG-CoA reductase that catalyzes the conversion of HMG-CoA to mevalonate which is a rate-limiting step in sterol biosynthesis localizes to the nuclear envelope overproduction induces the formation of karmellae
similar to uniprot|Q03631 Saccharomyces cerevisiae YML076C WAR1 zinc finger transcription factor
highly similar to uniprot|Q03630 Saccharomyces cerevisiae YML077W BET5 Component of the TRAPP (transport protein particle) complex which plays an essential role in the vesicular transport from endoplasmic reticulum to Golgi
similar to uniprot|P32568 Saccharomyces cerevisiae YDR011W SNQ2 ABC transporter
similar to uniprot|P47160 Saccharomyces cerevisiae YJR125C ENT3 Protein containing an N-terminal epsin-like domain involved in clathrin recruitment and traffic between the Golgi and endosomes associates with the clathrin adaptor Gga2p
highly similar to uniprot|P25719 Saccharomyces cerevisiae YML078W CPR3 Mitochondrial peptidyl-prolyl cis-trans isomerase (cyclophilin) catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues involved in protein refolding after import into mitochondria
similar to uniprot|P47161 Saccharomyces cerevisiae YJR126C VPS70
highly similar to uniprot|Q03629 Saccharomyces cerevisiae YML079W Uncharacterized protein with structural resemblance to plant storage and ligand binding proteins (canavalin glycinin auxin binding protein) and also to some plant and bacterial enzymes (epimerase germin)
similar to uniprot|P53759 Saccharomyces cerevisiae YML080W DUS1 Dihydrouridine synthase member of a widespread family of conserved proteins including Smm1p Dus3p and Dus4p modifies pre-tRNA(Phe) at U17
similar to uniprot|Q04545 Saccharomyces cerevisiae YML081W Hypothetical ORF
weakly similar to uniprot|P47163 Saccharomyces cerevisiae YJR129C Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family
similar to uniprot|P25335 Saccharomyces cerevisiae YIR029W DAL2 Allantoicase
similar to uniprot|P50087 Saccharomyces cerevisiae YGR235C Hypothetical ORF
similar to uniprot|P39676 Saccharomyces cerevisiae YGR234W YHB1 Flavohemoglobin may play a role in the oxidative stress response
weakly similar to uniprot|P38850 Saccharomyces cerevisiae YHR154W RTT107 Regulator of Ty1 Transposition Establishes Silent Chromatin involved in silencing
similar to uniprot|P32837 Saccharomyces cerevisiae YDL210W UGA4 Permease that serves as a gamma-aminobutyrate (GABA) transport protein involved in the utilization of GABA as a nitrogen source catalyzes the transport of putrescine and delta-aminolevulinic acid (ALA) localized to the vacuolar membrane
similar to uniprot|P17442 Saccharomyces cerevisiae YGR233C PHO81 Cyclin-dependent kinase (CDK) inhibitor regulates Pho80p-Pho85p and Pcl7p-Pho85p cyclin-CDK complexes in response to phosphate levels required for derepression of PHO5 transcriptionally regulated by Pho4p and Pho2p
similar to uniprot|P50086 Saccharomyces cerevisiae YGR232W NAS6 Regulatory non-ATPase subunit of the 26S proteasome homolog of the human oncoprotein gankyrin which interacts with the retinoblastoma tumor suppressor (Rb) and cyclin-dependent kinase 4/6
similar to uniprot|P50085 Saccharomyces cerevisiae YGR231C PHB2 Possible role in aging mitochondrial protein prohibitin homolog homolog of mammalian BAP37 and S. cerevisiae Phb1p
some similarities with uniprot|P50084 Saccharomyces cerevisiae YGR230W
similar to uniprot|P32566 Saccharomyces cerevisiae YGR229C SMI1 Protein involved in (1 3)-beta-glucan synthesis possibly through regulation of cell wall glucan and chitin synthesis chromatin binding protein 57 kDa nuclear protein
similar to uniprot|P50076 Saccharomyces cerevisiae YGR227W DIE2 Dolichyl-phosphoglucose-dependent glucosyltransferase of the ER functions in the dolichol pathway that synthesizes the dolichol-linked oligosaccharide precursor for N-linked protein glycosylation has a role in regulation of ITR1 and INO1
similar to uniprot|P38849 Saccharomyces cerevisiae YHR151C hypothetical ORF
similar to uniprot|P38848 Saccharomyces cerevisiae YHR150W PEX28 Peroxisomal integral membrane protein involved in regulation of peroxisome size and number genetic interactions suggest that Pex28p and Pex29p act at steps upstream of those mediated by Pex30p Pex31p and Pex32p
weakly similar to uniprot|P50082 Saccharomyces cerevisiae YGR225W AMA1 Required for sporulation highly induced during sporulation activator of meiotic anaphase promoting complex Required for sporulation highly induced during sporulation
similar to uniprot|P50079 Saccharomyces cerevisiae YGR223C HSV2 Phosphatidylinositol 3 5-bisphosphate-binding protein predicted to fold as a seven-bladed beta-propeller displays punctate cytoplasmic localization
similar to uniprot|P10834 Saccharomyces cerevisiae YGR222W PET54 Protein required for splicing of the COX1 intron AI5 beta also specifically required together with Pet122p and Pet494p for translation of the COX3 mRNA located in the mitochondrial inner membrane
highly similar to uniprot|P39522 Saccharomyces cerevisiae YJR016C ILV3 Dihydroxyacid dehydratase catalyzes third step in the common pathway leading to biosynthesis of branched-chain amino acids
some similarities with uniprot|P32900 Saccharomyces cerevisiae YHR149C SKG6 Protein of unknown function found in the bud tip and bud neck potential Cdc28p substrate
highly similar to uniprot|P32899 Saccharomyces cerevisiae YHR148W IMP3 Component of the SSU processome which is required for pre-18S rRNA processing essential protein that interacts with Mpp10p and mediates interactions of Imp4p and Mpp10p with U3 snoRNA
mitochondrial 54S ribosomal protein YmL16
highly similar to uniprot|P32904 Saccharomyces cerevisiae YHR147C MRPL6 Mitochondrial ribosomal protein of the large subunit
mitochondrial 54S ribosomal protein YmL9
highly similar to uniprot|P31334 Saccharomyces cerevisiae YGR220C MRPL9 Mitochondrial ribosomal protein of the large subunit
highly similar to uniprot|P30822 Saccharomyces cerevisiae YGR218W CRM1 Major karyopherin involved in export of proteins RNAs and ribosomal subunits from the nucleus
similar to uniprot|P33448 Saccharomyces cerevisiae YOR045W TOM6 involved in supporting the cooperativity between receptors and the general insertion pore and facilitating the release of preproteins from import components outer mitochondrial membrane protein component of the mitochondiral protein translocation complex associates with TOM40
highly similar to uniprot|P20449 Saccharomyces cerevisiae YOR046C DBP5 Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family involved in mRNA export from the nucleus
similar to uniprot|Q02792 Saccharomyces cerevisiae YOR048C RAT1 Nuclear 5' to 3' single-stranded RNA exonuclease involved in RNA metabolism including rRNA and snRNA processing as well as mRNA transcription termination
similar to uniprot|P36052 Saccharomyces cerevisiae YKL162C Hypothetical ORF
similar to uniprot|Q08417 Saccharomyces cerevisiae YOR049C RSB1 Suppressor of sphingoid long chain base (LCB) sensitivity of an LCB-lyase mutation putative integral membrane transporter or flippase that may transport LCBs from the cytoplasmic side toward the extracytoplasmic side of the membrane
similar to uniprot|P36148 Saccharomyces cerevisiae YKR067W GPT2 Glycerol-3-phosphate acyltransferase located in both lipid particles and the ER involved in the stepwise acylation of glycerol-3-phosphate and dihydroxyacetone which are intermediate steps in lipid biosynthesis
highly similar to uniprot|P36149 Saccharomyces cerevisiae YKR068C BET3 Hydrophilic protein that acts in conjunction with SNARE proteins in targeting and fusion of ER to Golgi transport vesicles component of the TRAPP (transport protein particle) complex
similar to uniprot|Q6Q5I2 Saccharomyces cerevisiae YOR051C which is a model system for studying replication of positive-strand RNA viruses in their natural hosts
similar to uniprot|P36150 Saccharomyces cerevisiae YKR069W MET1 S-adenosyl-L-methionine uroporphyrinogen III transmethylase
highly similar to uniprot|P36151 Saccharomyces cerevisiae YKR070W Hypothetical ORF
some similarities with uniprot|O00017 Saccharomyces cerevisiae YOR052C
similar to uniprot|P36152 Saccharomyces cerevisiae YKR071C DRE2
some similarities with uniprot|P36024 Saccharomyces cerevisiae YKR072C SIS2 Involved in cell cycle control and ion homeostasis sit4 suppressor
similar to uniprot|O00021 Saccharomyces cerevisiae YOR056C NOB1 Nin1 (One) Binding protein essential nuclear protein involved in proteasome maturation and synthesis of 40S ribosome subunits required for cleavage of the 20S pre-rRNA to generate the mature 18S rRNA.
similar to uniprot|Q08446 Saccharomyces cerevisiae YOR057W SGT1 Probable cochaperone regulates activity of Cyr1p (adenylyl cyclase)involved in assembly of the kinetochore complex associates with the SCF (Skp1p/Cdc53p/F box protein) ubiquitin ligase complex
similar to uniprot|P50275 Saccharomyces cerevisiae YOR058C ASE1 Member of a family of microtubule-associated proteins (MAPs) that function at the mitotic spindle midzone required for spindle elongation undergoes cell cycle-regulated degradation by anaphase promoting complex potential Cdc28p substrate
highly similar to gnl|GLV|CAGL0G02013g Candida glabrata CAGL0G02013g and similar to YKR074W uniprot|P36154 Saccharomyces cerevisiae YKR074W Hypothetical ORF
similar to uniprot|O00022 Saccharomyces cerevisiae YOR059C Hypothetical ORF
similar to uniprot|O00023 Saccharomyces cerevisiae YOR060C Protein required for cell viability
highly similar to uniprot|P19454 Saccharomyces cerevisiae YOR061W CKA2 may have a role in regulation and/or execution of the eukaryotic cell cycle alpha' subunit of casein kinase II
some similarities with uniprot|P36155 Saccharomyces cerevisiae or YOR062c uniprot|P36025 Saccharomyces cerevisiae
highly similar to uniprot|P14126 Saccharomyces cerevisiae YOR063W
weakly similar to uniprot|O00025 Saccharomyces cerevisiae YOR064C YNG1 Yeast homolog of mammalian Ing1 histone acetyltransferase complex component
highly similar to gnl|GLV|CAGL0L10406g Candida glabrata CAGL0L10406g and similar to YOR065W uniprot|P07143 Saccharomyces cerevisiae YOR065W CYT1 Cytochrome c1 component of the mitochondrial respiratory chain expression is regulated by the heme-activated glucose- repressed Hap2p/3p/4p/5p CCAAT-binding complex
weakly similar to uniprot|P41696 Saccharomyces cerevisiae YOR113W AZF1 Zinc-finger transcription factor involved in induction of CLN3 transcription in response to glucose genetic and physical interactions indicate a possible role in mitochondrial transcription or genome maintenance
weakly similar to uniprot|Q12219 Saccharomyces cerevisiae YOR114W Hypothetical ORF
similar to uniprot|Q99394 Saccharomyces cerevisiae YOR115C TRS33 Component of the targeting complex (TRAPP) involved in ER to Golgi membrane traffic
similar to uniprot|P38822 Saccharomyces cerevisiae YHR114W BZZ1 SH3 domain protein implicated in the regulation of actin polymerization able to recruit actin polymerization machinery through its SH3 domains colocalizes with cortical actin patches and Las17p interacts with type I myosins
similar to uniprot|P53925 Saccharomyces cerevisiae YNL115C Hypothetical ORF
similar to uniprot|P53924 Saccharomyces cerevisiae YNL116W DMA2 Protein involved in regulating spindle position and orientation functionally redundant with Dma1p homolog of S. pombe Dma1 and H. sapiens Chfr
highly similar to uniprot|P30952 Saccharomyces cerevisiae YNL117W MLS1 Malate synthase enzyme of the glyoxylate cycle involved in utilization of non-fermentable carbon sources expression is subject to carbon catabolite repression localizes in peroxisomes during growth in oleic acid medium
similar to uniprot|P53550 Saccharomyces cerevisiae YNL118C DCP2 Protein required for the decapping of mRNAs functions to allow the production of active Dcp1p contains a pyrophosphatase MutT motif and several alpha-helical leucine-rich motifs
similar to uniprot|P53923 Saccharomyces cerevisiae YNL119W NCS2 Protein with a role in urmylation and in invasive and pseudohyphal growth inhibits replication of Brome mosaic virus in S. cerevisiae which is a model system for studying replication of positive-strand RNA viruses in their natural hosts
similar to uniprot|Q3E833 Saccharomyces cerevisiae YKR095W-A
similar to uniprot|P36168 Saccharomyces cerevisiae YKR096W Hypothetical ORF
weakly similar to uniprot|P40455 Saccharomyces cerevisiae YIL152W Hypothetical ORF
highly similar to uniprot|P10963 Saccharomyces cerevisiae YKR097W PCK1 Phosphoenolpyruvate carboxykinase key enzyme in gluconeogenesis catalyzes early reaction in carbohydrate biosynthesis glucose represses transcription and accelerates mRNA degradation regulated by Mcm1p and Cat8p located in the cytosol
similar to uniprot|P40454 Saccharomyces cerevisiae YIL153W RRD1 Resistant to Rapamycin Deletion
similar to uniprot|P32351 Saccharomyces cerevisiae YIL154C IMP2' Transcriptional activator involved in maintenance of ion homeostasis and protection against DNA damage caused by bleomycin and other oxidants contains a C-terminal leucine-rich repeat
highly similar to gnl|GLV|KLLA0A00418g Kluyveromyces lactis KLLA0A00418g and similar to YIL155C uniprot|P32191 Saccharomyces cerevisiae YIL155C GUT2 Mitochondrial glycerol-3-phosphate dehydrogenase expression is repressed by both glucose and cAMP and derepressed by non-fermentable carbon sources in a Snf1p Rsf1p Hap2/3/4/5 complex dependent manner
similar to uniprot|P40453 Saccharomyces cerevisiae YIL156W UBP7 Ubiquitin-specific protease that cleaves ubiquitin-protein fusions
weakly similar to uniprot|P22035 Saccharomyces cerevisiae YKR099W BAS1 Myb-related transcription factor involved in regulating basal and induced expression of genes of the purine and histidine biosynthesis pathways
highly similar to uniprot|Q2V2P4 Saccharomyces cerevisiae YIL156W-B
similar to uniprot|P40452 Saccharomyces cerevisiae YIL157C FMP35 The authentic non-tagged protein was localized to the mitochondria
similar to uniprot|P36169 Saccharomyces cerevisiae YKR100C SKG1 Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and bud
some similarities with uniprot|P40450 Saccharomyces cerevisiae YIL159W BNR1 Formin nucleates the formation of linear actin filaments involved in cell processes such as budding and mitotic spindle orientation which require the formation of polarized actin cables functionally redundant with BNI1
highly similar to uniprot|P27796 Saccharomyces cerevisiae YIL160C POT1 3-ketoacyl-CoA thiolase with broad chain length specificity cleaves 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA during beta-oxidation of fatty acids
similar to uniprot|P40449 Saccharomyces cerevisiae YIL161W Hypothetical ORF
similar to uniprot|P15202 Saccharomyces cerevisiae YDR256C CTA1 Catalase A breaks down hydrogen peroxide in the peroxisomal matrix formed by acyl-CoA oxidase (Pox1p) during fatty acid beta-oxidation
similar to uniprot|P38124 Saccharomyces cerevisiae YBR008C FLR1 Plasma membrane multidrug transporter member of the major facilitator superfamily involved in efflux of fluconazole diazaborine benomyl methotrexate and other drugs
some similarities with uniprot|Q04893 Saccharomyces cerevisiae YMR317W Hypothetical ORF
some similarities with uniprot|P15365 Saccharomyces cerevisiae YJR152W DAL5 Allantoin permease ureidosuccinate permease expression is constitutive but sensitive to nitrogen catabolite repression
similar to uniprot|Q06598 Saccharomyces cerevisiae YPR201W ARR3 Arsenite transporter of the plasma membrane required for resistance to arsenic compounds transcription is activated by Arr1p in the presence of arsenite
weakly similar to uniprot|P53176 Saccharomyces cerevisiae YGL051W MST27 Putative integral membrane protein, involved in vesicle formation; forms complex with Mst28p; member of DUP240 gene family; binds COPI and COPII vesicles and weakly similar to YAR033W uniprot|P39552 Saccharomyces cerevisiae YAR033W MST28 Putative integral membrane protein, involved in vesicle formation; forms complex with Mst27p; member of DUP240 gene family; binds COPI and COPII vesicles