Zygosaccharomyces rouxii strain CBS732 chromosome A complete sequence.
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Zygosaccharomyces.
Comparative genomics of protoploid Saccharomycetaceae
Submitted (25-SEP-2017) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (04-JUN-2009) Genoscope - Centre National de Sequencage : BP 191 91006 EVRY cedex - FRANCE (E-mail : seqref@genoscope.cns.fr - Web : www.genoscope.cns.fr)
PROVISIONAL REFSEQ: This record has not yet been subject to final\nNCBI review. The reference sequence is identical to CU928173.\nThe Zygosaccharomyces rouxii sequence is made of 7 chromosomes (A\nto G). The sequence was annotated by the Genolevures Consortium.\nFor more information go to\nhttp://cbi.labri.fr/Genolevures.\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: INSDC submitter\nAnnotation Status :: Full annotation\nAnnotation Pipeline :: Eukaryotic Annotation Propagation Pipeline\n##Genome-Annotation-Data-END##
some similarities with uniprot|P36034 Saccharomyces cerevisiae YKL219W COS9
some similarities with uniprot|P47187 Saccharomyces cerevisiae YJR161C COS5
weakly similar to uniprot|P47187 Saccharomyces cerevisiae YJR161C COS5 Protein of unknown function member of a family of conserved often subtelomerically-encoded proteins
some similarities with uniprot|Q70DG7 Saccharomyces cerevisiae YHL044W Putative integral membrane protein member of DUP240 gene family
highly similar to uniprot|Q02895 Saccharomyces cerevisiae YPL088W Putative aryl alcohol dehydrogenase transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance
similar to uniprot|P43548 Saccharomyces cerevisiae YFL055W AGP3 Low-affinity amino acid permease may act to supply the cell with amino acids as nitrogen source in nitrogen-poor conditions transcription is induced under conditions of sulfur limitation
similar to uniprot|P38358 Saccharomyces cerevisiae YBR293W VBA2 Permease of basic amino acids in the vacuolar membrane
similar to uniprot|P40445 Saccharomyces cerevisiae YIL166C
similar to uniprot|P40579 and to YIR036C uniprot|P40580 Saccharomyces cerevisiae, Hypothetical ORFs
similar to uniprot|P05085 Saccharomyces cerevisiae YML099C ARG81 Zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type involved in the regulation of arginine-responsive genes acts with Arg80p and Arg82p
similar to uniprot|P11747 Saccharomyces cerevisiae YML098W
similar to uniprot|Q03103 Saccharomyces cerevisiae YML130C ERO1 Glycoprotein required for oxidative protein folding in the endoplasmic reticulum
similar to uniprot|P54787 Saccharomyces cerevisiae YML097C
similar to uniprot|Q04489 Saccharomyces cerevisiae YML096W Hypothetical ORF
similar to uniprot|P06838 Saccharomyces cerevisiae YML095C RAD10 Single-stranded DNA endonuclease (with Rad1p) cleaves single-stranded DNA during nucleotide excision repair and double-strand break repair subunit of Nucleotide Excision Repair Factor 1 (NEF1) homolog of human XPF protein
highly similar to uniprot|Q04493 Saccharomyces cerevisiae YML094W GIM5 Subunit of the heterohexameric cochaperone prefoldin complex which binds specifically to cytosolic chaperonin and transfers target proteins to it
similar to gnl|GLV|CAGL0H06985g Candida glabrata CAGL0H06985g and weakly similar to YML093W uniprot|Q04500 Saccharomyces cerevisiae YML093W UTP14 Nucleolar protein component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
highly similar to uniprot|P23639 Saccharomyces cerevisiae YML092C PRE8 20S proteasome beta-type subunit
similar to uniprot|P39103 Saccharomyces cerevisiae YML129C COX14 Mitochondrial membrane protein required for assembly of cytochrome c oxidase
similar to uniprot|Q03104 Saccharomyces cerevisiae YML128C MSC1 Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum msc1 mutants are defective in directing meiotic recombination events to homologous chromatids
similar to uniprot|Q03124 Saccharomyces cerevisiae YML127W RSC9 One of 15 subunits of the 'Remodel the Structure of Chromatin' (RSC) complex DNA-binding protein involved in the synthesis of rRNA and in transcriptional repression and activation of genes regulated by the Target of Rapamycin (TOR) pathway
similar to uniprot|Q02773 Saccharomyces cerevisiae YML091C RPM2 Protein component of mitochondrial RNase P along with the mitochondrially-encoded RNA subunit RPM1 Rnase P removes 5' extensions from tRNA precursors Rpm2p is also involved in maturation of RPM1 and in translation of mitochondrial mRNAs
highly similar to gnl|GLV|KLLA0D10505g Kluyveromyces lactis KLLA0D10505g and highly similar to YML126C uniprot|P54839 Saccharomyces cerevisiae YML126C ERG13 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase catalyzes the formation of HMG-CoA from acetyl-CoA and acetoacetyl-CoA involved in the second step in mevalonate biosynthesis
similar to uniprot|Q04511 Saccharomyces cerevisiae YML088W UFO1 F-box receptor protein subunit of the Skp1-Cdc53-F-box receptor (SCF) E3 ubiquitin ligase complex binds to phosphorylated Ho endonuclease allowing its ubiquitylation by SCF and subsequent degradation
similar to uniprot|Q12746 Saccharomyces cerevisiae YML125C Protein required for cell viability
highly similar to uniprot|P54783 Saccharomyces cerevisiae YML086C ALO1 D-Arabinono-1 4-lactone oxidase catalyzes the final step in biosynthesis of D-erythroascorbic acid which is protective against oxidative stress
highly similar to uniprot|P09733 Saccharomyces cerevisiae YML085C TUB1 Alpha-tubulin associates with beta-tubulin (Tub2p) to form tubulin dimer which polymerizes to form microtubules
similar to uniprot|P25297 Saccharomyces cerevisiae YML123C PHO84 High-affinity inorganic phosphate (Pi) transporter and low-affinity manganese transporter regulated by Pho4p and Spt7p mutation confers resistance to arsenate exit from the ER during maturation requires Pho86p
similar to uniprot|P29704 Saccharomyces cerevisiae YHR190W ERG9 Farnesyl-diphosphate farnesyl transferase (squalene synthase) joins two farnesyl pyrophosphate moieties to form squalene in the sterol biosynthesis pathway
similar to uniprot|P38876 Saccharomyces cerevisiae YHR189W PTH1 One of two (see also PTH2) mitochondrially-localized peptidyl-tRNA hydrolases dispensable for cell growth and for mitochondrial respiration
highly similar to uniprot|Q00582 Saccharomyces cerevisiae YML121W GTR1 Cytoplasmic GTP binding protein and negative regulator of the Ran/Tc4 GTPase cycle through its homolog and binding partner Gtr2p involved in phosphate transport and invasive growth human RagA and RagB proteins are functional homologs
some similarities with uniprot|P40463 Saccharomyces cerevisiae YIL135C VHS2 Gene whose overexpression suppresses the synthetic lethality of the hal3 sit4 double mutation
similar to uniprot|P32048 Saccharomyces cerevisiae YNL073W MSK1 Mitochondrial lysine-tRNA synthetase required for import of both aminoacylated and deacylated forms of tRNA(Lys) into mitochondria
weakly similar to uniprot|Q75D69 Ashbya gossypii ABR154C ABR154Cp
similar to uniprot|P53942 Saccharomyces cerevisiae YNL072W RNH201 Ribonuclease H2 catalytic subunit removes RNA primers during Okazaki fragment synthesis cooperates with Rad27p nuclease
similar to uniprot|Q08911 Saccharomyces cerevisiae YOR388C FDH1 NAD()-dependent formate dehydrogenase may protect cells from exogenous formate
similar to uniprot|P12695 Saccharomyces cerevisiae YNL071W LAT1 Dihydrolipoamide acetyltransferase component (E2) of pyruvate dehydrogenase complex which catalyzes the oxidative decarboxylation of pyruvate to acetyl-CoA
similar to uniprot|P53507 Saccharomyces cerevisiae YNL070W TOM7 Involved in mitochondrial protein import translocase of the outer mito. membrane
similar to uniprot|P40464 Saccharomyces cerevisiae YIL134W FLX1 Protein required for transport of flavin adenine dinucleotide (FAD) from mitochondria where it is synthesized from riboflavin to the cytosol
similar to uniprot|P26784 Saccharomyces cerevisiae YIL133C RPL16A N-terminally acetylated protein component of the large (60S) ribosomal subunit, binds to 5.8 S rRNA; has similarity to Rpl16Bp, E. coli L13 and rat L13a ribosomal proteins; transcriptionally regulated by Rap1p and to YNL069C uniprot|P26785 Saccharomyces cerevisiae YNL069C RPL16B N-terminally acetylated protein component of the large (60S) ribosomal subunit, binds to 5.8 S rRNA; has similarity to Rpl16Ap, E. coli L13 and rat L13a ribosomal proteins; transcriptionally regulated by Rap1p
similar to uniprot|P40465 Saccharomyces cerevisiae YIL132C CSM2 Protein required for accurate chromosome segregation during meiosis
some similarities with uniprot|P41813 Saccharomyces cerevisiae YNL068C FKH2 Transcription factor of the forkhead family that regulates the cell cycle and pseudohyphal growth also involved in chromatin silencing at HML and HMR potential Cdc28p substrate
similar to uniprot|P40468 Saccharomyces cerevisiae YIL129C TAO3 Identified in a hunt for mutants that activate OCH1 transcription Transcriptional Activator of OCH1
similar to uniprot|P40469 Saccharomyces cerevisiae YIL128W MET18 DNA repair and TFIIH regulator required for both nucleotide excision repair (NER) and RNA polymerase II (RNAP II) transcription possible role in assembly of a multiprotein complex(es) required for NER and RNAP II transcription
similar to uniprot|P40470 Saccharomyces cerevisiae YIL127C Hypothetical ORF
similar to uniprot|P32597 Saccharomyces cerevisiae YIL126W STH1 helicase related protein snf2 homolog
highly similar to uniprot|P05738 Saccharomyces cerevisiae uniprot|P05738 Saccharomyces cerevisiae YGL147C RPL9A Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl9Bp and has similarity to E. coli L6 and rat L9 ribosomal proteins and to YNL067W uniprot|P51401 Saccharomyces cerevisiae YNL067W RPL9B Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl9Ap and has similarity to E. coli L6 and rat L9 ribosomal proteins
highly similar to uniprot|P20967 Saccharomyces cerevisiae YIL125W KGD1 Component of the mitochondrial alpha-ketoglutarate dehydrogenase complex which catalyzes a key step in the tricarboxylic acid (TCA) cycle the oxidative decarboxylation of alpha-ketoglutarate to form succinyl-CoA
similar to uniprot|P40471 Saccharomyces cerevisiae YIL124W AYR1 NADPH-dependent 1-acyl dihydroxyacetone phosphate reductase found in lipid particles and ER involved in phosphatidic acid biosynthesis and required for spore germination capable of metabolizing mammalian steroid hormones
some similarities with gnl|GLV|CAGL0J09922g Candida glabrata CAGL0J09922g and some similarities with uniprot|P40472 Saccharomyces cerevisiae YIL123W SIM1 (putative) invovled in control of DNA replication or uniprot|P53616 Saccharomyces cerevisiae YNL066W SUN4 Protein involved in the aging process
weakly similar to uniprot|P40473 Saccharomyces cerevisiae YIL122W
similar to uniprot|P40474 Saccharomyces cerevisiae YIL121W QDR2 Multidrug transporter required for resistance to quinidine barban cisplatin and bleomycin member of the major facilitator superfamily of transporters conferring multiple drug resistance (MFS-MDR)
highly similar to gnl|GLV|CAGL0J09966g Candida glabrata CAGL0J09966g and similar to YNL064C uniprot|P25491 Saccharomyces cerevisiae YNL064C YDJ1 yeast dnaJ homolog (nuclear envelope protein) heat shock protein
similar to uniprot|P53944 Saccharomyces cerevisiae YNL063W MTQ1
similar to uniprot|P41814 Saccharomyces cerevisiae YNL062C GCD10 Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p required for the modification of the adenine at position 58 in tRNAs especially tRNAi-Met first identified as a negative regulator of GCN4 expression
similar to uniprot|P40991 Saccharomyces cerevisiae YNL061W NOP2 Probable RNA m(5)C methyltransferase essential for processing and maturation of 27S pre-rRNA and large ribosomal subunit biogenesis localized to the nucleolus
highly similar to uniprot|P53946 Saccharomyces cerevisiae YNL059C ARP5 Nuclear actin-related protein involved in chromatin remodeling component of chromatin-remodeling enzyme complexes
highly similar to uniprot|Q00245 Saccharomyces cerevisiae YIL118W RHO3 Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins involved in the establishment of cell polarity GTPase activity positively regulated by the GTPase activating protein (GAP) Rgd1p
some similarities with uniprot|P53947 Saccharomyces cerevisiae YNL058C
highly similar to uniprot|P53949 Saccharomyces cerevisiae YNL056W Cytoplasmic protein required for replication of Brome mosaic virus in S. cerevisiae which is a model system for studying replication of positive- strand RNA viruses in their natural hosts
highly similar to uniprot|P07172 Saccharomyces cerevisiae YIL116W HIS5 Histidinol-phosphate aminotransferase catalyzes the seventh step in histidine biosynthesis responsive to general control of amino acid biosynthesis mutations cause histidine auxotrophy and sensitivity to Cu Co and Ni salts
similar to uniprot|P40477 Saccharomyces cerevisiae YIL115C NUP159 Subunit of the nuclear pore complex that is found exclusively on the cytoplasmic side forms a subcomplex with Nup82p and Nsp1p required for mRNA export
highly similar to uniprot|P04840 Saccharomyces cerevisiae YNL055C POR1 Mitochondrial porin (voltage-dependent anion channel) outer membrane protein required for the maintenance of mitochondrial osmotic stability and mitochondrial membrane permeability
weakly similar to uniprot|P53950 Saccharomyces cerevisiae YNL054W VAC7 Integral vacuolar membrane protein may function to regulate Fab1p kinase activity
weakly similar to uniprot|P38590 Saccharomyces cerevisiae YNL053W MSG5 Dual-specificity protein phosphatase required for maintenance of a low level of signaling through the cell integrity pathway regulates and is regulated by Slt2p also required for adaptive response to pheromone
similar to uniprot|P53960 Saccharomyces cerevisiae YNL040W Hypothetical ORF
similar to uniprot|P53962 Saccharomyces cerevisiae YNL035C Hypothetical ORF
similar to uniprot|P40494 Saccharomyces cerevisiae YIL095W PRK1 Protein serine/threonine kinase regulates the organization and function of the actin cytoskeleton through the phosphorylation of the Pan1p-Sla1p-End3p protein complex
highly similar to uniprot|P53973 Saccharomyces cerevisiae YNL021W HDA1 Putative catalytic subunit of a class II histone deacetylase complex that also contains Hda2p and Hda3p Hda1p interacts with the Hda2p-Hda3p subcomplex to form an active tetramer deletion increases histone H2B H3 and H4 acetylation
similar to uniprot|P53972 Saccharomyces cerevisiae YNL022C
highly similar to uniprot|P40495 Saccharomyces cerevisiae YIL094C LYS12 Homo-isocitrate dehydrogenase an NAD-linked mitochondrial enzyme required for the fourth step in the biosynthesis of lysine in which homo-isocitrate is oxidatively decarboxylated to alpha-ketoadipate
similar to uniprot|P53971 Saccharomyces cerevisiae YNL023C
mitochondrial 37S ribosomal protein RSM25
similar to uniprot|P40496 Saccharomyces cerevisiae YIL093C RSM25 Mitochondrial ribosomal protein of the small subunit
highly similar to uniprot|Q8TGJ3 Saccharomyces cerevisiae YNL024C-A Identified by gene-trapping microarray-based expression analysis and genome-wide homology searching
similar to uniprot|P40498 Saccharomyces cerevisiae YIL091C Protein required for cell viability
similar to uniprot|P40499 Saccharomyces cerevisiae YIL090W ICE2 Integral ER membrane protein with type-III transmembrane domains mutations cause defects in cortical ER morphology in both the mother and daughter cells
highly similar to uniprot|P47821 Saccharomyces cerevisiae YNL025C SSN8 Component of RNA polymerase II holoenzyme involved in RNA pol II carboxy-terminal domain phosphorylation
similar to uniprot|P40501 Saccharomyces cerevisiae YIL088C AVT7 Putative transporter member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters
some similarities with uniprot|P53965 Saccharomyces cerevisiae YNL032W SIW14 Tyrosine phosphatase that plays a role in actin filament organization and endocytosis localized to the cytoplasm
similar to uniprot|P40502 Saccharomyces cerevisiae YIL087C Hypothetical ORF
highly similar to uniprot|P61830 Saccharomyces cerevisiae YNL031C one of two identical histone H3 proteins
highly similar to uniprot|P02309 YBR009C and to uniprot|P02309 YNL030W Saccharomyces cerevisiae, HHF1 and HHF2, two identical histone H4 proteins; core histone required for chromatin assembly and chromosome function; contributes to telomeric silencing; N-terminal domain involved in maintaining genomic integrity
similar to uniprot|P40504 Saccharomyces cerevisiae YIL085C KTR7 Putative mannosyltransferase involved in protein glycosylation member of the KRE2/MNT1 mannosyltransferase family or uniprot|P53966 Saccharomyces cerevisiae YNL029C KTR5
similar to uniprot|P40505 Saccharomyces cerevisiae YIL084C
similar to uniprot|Q04235 Saccharomyces cerevisiae YML005W TRM12 Putative tRNA methyltransferase has a role in tRNA modification S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family
similar to uniprot|Q288C3 Torulaspora delbrueckii CRZ1 Calcineurin-responsive zinc finger transcription factor and some similarites with YNL027W uniprot|P53968 Saccharomyces cerevisiae YNL027W CRZ1 Transcription factor that activates transcription of genes involved in stress response nuclear localization is positively regulated by calcineurin-mediated dephosphorylation
similar to uniprot|P53969 Saccharomyces cerevisiae YNL026W SAM50 Essential component of the Sorting and Assembly Machinery (SAM complex) of the mitochondrial outer membrane the authentic non-tagged protein was localized to the mitochondria
highly similar to uniprot|P40506 Saccharomyces cerevisiae YIL083C Homolog to human PPCS
similar to uniprot|P32588 Saccharomyces cerevisiae YNL016W PUB1 Poly(A) RNA-binding protein abundant mRNP-component protein hypothesized to bind a pool of non-translatable mRNAs not reported to associate with polyribosomes
similar to uniprot|P25037 Saccharomyces cerevisiae YDL122W UBP1 Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins cleaves at the C terminus of ubiquitin fusions irrespective of their size capable of cleaving polyubiquitin chains
weakly similar to uniprot|Q07541 Saccharomyces cerevisiae YDL121C Hypothetical ORF
similar to uniprot|Q07540 Saccharomyces cerevisiae YDL120W YFH1 Yeast Frataxin Homologue mitochondrial protein that regulates mitochondrial iron accumulation
similar to uniprot|P22855 Saccharomyces cerevisiae YGL156W AMS1 vacuolar alpha mannosidase
similar to uniprot|P18898 Saccharomyces cerevisiae YGL155W CDC43 Beta subunit of geranylgeranyltransferase type I catalyzes geranylgeranylation to the cysteine residue in proteins containing a C-terminal CaaX sequence ending in Leu or Phe has substrates important for morphogenesis
similar to uniprot|Q07534 Saccharomyces cerevisiae YDL119C Hypothetical ORF
similar to uniprot|P50113 Saccharomyces cerevisiae YGL154C LYS5 Phosphopantetheinyl transferase involved in lysine biosynthesis converts inactive apo-form of Lys2p (alpha-aminoadipate reductase) into catalytically active holo-form by posttranslational addition of phosphopantetheine
similar to uniprot|P53112 Saccharomyces cerevisiae YGL153W PEX14 Peroxisomal membrane protein that is a central component of the peroxisomal protein import machinery interacts with PTS1 (Pex5p) and PTS2 (Pex7p) peroxisomal matrix protein signal recognition factors and membrane receptor Pex13p
similar to uniprot|P53114 Saccharomyces cerevisiae YGL151W NUT1 Component of the RNA polymerase II mediator complex which is required for transcriptional activation and also has a role in basal transcription
similar to uniprot|P53115 Saccharomyces cerevisiae YGL150C INO80 ATPase that forms a large complex containing actin and several actin-related proteins
highly similar to uniprot|P28777 Saccharomyces cerevisiae YGL148W ARO2 Bifunctional chorismate synthase and flavin reductase catalyzes the conversion of 5-enolpyruvylshikimate 3-phosphate (EPSP) to form chorismate which is a precursor to aromatic amino acids
similar to uniprot|Q07533 Saccharomyces cerevisiae YDL117W CYK3 SH3-domain protein located in the mother-bud neck and the cytokinetic actin ring mutant phenotype and genetic interactions suggest a role in cytokinesis
similar to uniprot|P52891 Saccharomyces cerevisiae YDL116W NUP84 Subunit of the nuclear pore complex (NPC) forms a subcomplex with Nup85p Nup120p Nup145p-C Sec13p and Seh1p that plays a role in nuclear mRNA export and NPC biogenesis
similar to uniprot|P32580 Saccharomyces cerevisiae YPL029W SUV3 ATP-dependent RNA helicase component of the mitochondrial degradosome
highly similar to uniprot|P41338 Saccharomyces cerevisiae YPL028W ERG10 Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) cytosolic enzyme that transfers an acetyl group from one acetyl-CoA molecule to another forming acetoacetyl-CoA involved in the first step in mevalonate biosynthesis
similar to uniprot|Q03786 Saccharomyces cerevisiae YDR248C Hypothetical ORF
similar to uniprot|Q12505 Saccharomyces cerevisiae YPL026C SKS1 multicopy suppressor of snf3 and grr1 mutants serine/threonine protein kinase homologous to Ran1p
similar to uniprot|Q03784 Saccharomyces cerevisiae YDR246W TRS23 Component of the targeting complex (TRAPP) involved in ER to Golgi membrane traffic
similar to uniprot|Q02685 Saccharomyces cerevisiae YPL024W RMI1 Protein of unknown function GFP tagged protein localizes to the cytoplasm and nucleus
highly similar to uniprot|P46151 Saccharomyces cerevisiae YPL023C MET12 Isozyme of methylenetetrahydrofolate reductase catalyzes the reduction of 5 10-methylenetetrahydrofolate to 5-methyltetrahydrofolate in the methionine biosynthesis pathway
similar to uniprot|P06777 Saccharomyces cerevisiae YPL022W RAD1 Single-stranded DNA endonuclease
some similarities with uniprot|P09547 Saccharomyces cerevisiae YPL016W SWI1 Global transcription activator that acts in complex with Snf2p Snf5p Snf6p and Swi3p to assist gene-specific activators involved in the regulation of expression of many genes including ADH1 ADH2 GAL1 HO INO1 and SUC2 Zinc-finger transcription factor
similar to uniprot|P50108 Saccharomyces cerevisiae YDR245W MNN10 Subunit of a Golgi mannosyltransferase complex also containing Anp1p Mnn9p Mnn11p and Hoc1p that mediates elongation of the polysaccharide mannan backbone membrane protein of the mannosyltransferase family
similar to uniprot|P35056 Saccharomyces cerevisiae YDR244W PEX5 Essential for import of proteins with SKL-like import signal into peroxisomal matrix 69-kDa protein containing tetratricopeptide repeat (TPR)
similar to uniprot|P23394 Saccharomyces cerevisiae YDR243C PRP28 RNA helicase in the DEAD-box family involved in RNA isomerization at the 5' splice site
similar to uniprot|Q12046 Saccharomyces cerevisiae YDL209C CWC2 Protein involved in pre-mRNA splicing
similar to uniprot|P19735 Saccharomyces cerevisiae YBR055C PRP6 Splicing factor component of the U4/U6-U5 snRNP complex
similar to uniprot|P40971 Saccharomyces cerevisiae YDR034C LYS14 Transcriptional activator involved in regulation of genes of the lysine biosynthesis pathway requires 2-aminoadipate semialdehyde as co-inducer
similar to uniprot|Q12335 Saccharomyces cerevisiae YDR032C PST2
similar to uniprot|P38235 Saccharomyces cerevisiae YBR053C Hypothetical ORF
similar to uniprot|P38079 Saccharomyces cerevisiae YBR054W YRO2 Putative plasma membrane protein of unknown function transcriptionally regulated by Haa1p green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and bud
highly similar to uniprot|Q12335 Saccharomyces cerevisiae YDR032C PST2 Protein of unknown function with similarity to members of a family of flavodoxin-like proteins; induced by oxidative stress in a Yap1p dependent manner; GFP-fusion protein localizes to the cytoplasm in a punctate pattern
similar to uniprot|Q07789 Saccharomyces cerevisiae YDR031W Hypothetical ORF
similar to uniprot|Q12021 Saccharomyces cerevisiae YDR030C RAD28 Protein involved in transcription-coupled repair nucleotide excision repair of UV-induced DNA lesions homolog of human CSA protein
weakly similar to uniprot|Q00816 Saccharomyces cerevisiae YDR028C REG1 Regulatory subunit of type 1 protein phosphatase Glc7p involved in negative regulation of glucose-repressible genes involved in RNA processing
similar to uniprot|Q12071 Saccharomyces cerevisiae YDR027C VPS54 Component of the GARP (Golgi-associated retrograde protein) complex
similar to gnl|GLV|KLLA0F04389g Kluyveromyces lactis KLLA0F04389g and some similarites with YDR026C uniprot|Q12457 Saccharomyces cerevisiae YDR026C Hypothetical ORF
highly similar to uniprot|P26781 Saccharomyces cerevisiae YDR025W RPS11A Protein component of the small (40S) ribosomal subunit or uniprot|P26781 Saccharomyces cerevisiae YBR048W RPS11B
similar to uniprot|P38231 Saccharomyces cerevisiae YBR047W FMP23 The authentic non-tagged protein was localized to the mitochondria
highly similar to uniprot|P38230 Saccharomyces cerevisiae YBR046C ZTA1 Zeta-crystallin homolog
weakly similar to uniprot|P38229 Saccharomyces cerevisiae YBR045C GIP1 Meiosis-specific protein proposed to be a regulatory subunit of the protein phosphatase Glc7p required for spore wall formation and proper septin organization
highly similar to uniprot|P07284 Saccharomyces cerevisiae YDR023W SES1 seryl-tRNA synthetase
similar to uniprot|Q03939 Saccharomyces cerevisiae YDR022C CIS1 Protein involved in microtubule assembly
highly similar to uniprot|Q12099 Saccharomyces cerevisiae YDR021W FAL1 Nucleolar protein required for maturation of 18S rRNA member of the eIF4A subfamily of DEAD-box ATP-dependent RNA helicases
similar to uniprot|Q12084 Saccharomyces cerevisiae YDR020C Hypothetical ORF
similar to uniprot|P38228 Saccharomyces cerevisiae YBR044C TCM62 mitochondrial protein (putative) chaperone
similar to YDR019C, uniprot|P48015 Saccharomyces cerevisiae YDR019C (GCV1)
similar to YBR043C, uniprot|P38227 Saccharomyces cerevisiae YBR043C (QDR3)
similar to uniprot|P38226 Saccharomyces cerevisiae YBR042C Hypothetical ORF
similar to uniprot|P38225 Saccharomyces cerevisiae YBR041W FAT1 Fatty acid transporter and very long-chain fatty acyl-CoA synthetase may form a complex with Faa1p or Faa4p that imports and activates exogenous fatty acids
similar to uniprot|P38224 Saccharomyces cerevisiae YBR040W FIG1 Integral membrane protein required for efficient mating may participate in or regulate the low affinity Ca2 influx system which affects intracellular signaling and cell-cell fusion during mating
highly similar to uniprot|P38077 Saccharomyces cerevisiae YBR039W ATP3 Gamma subunit of the F1 sector of mitochondrial F1F0 ATP synthase which is a large evolutionarily conserved enzyme complex required for ATP synthesis
some similarities with uniprot|Q7LGR2 Saccharomyces cerevisiae YDR017C KCS1 Inositol hexaphosphate kinase phosphorylates inositol hexakisphosphate (InsP6) to diphosphoinositol polyphosphates required for proper vacuole morphology and involved in salt stress response contains two leucine heptad repeats
similar to gnl|GLV|CAGL0D04394g Candida glabrata CAGL0D04394g and some similarities with uniprot|Q12248 Saccharomyces cerevisiae YDR016C DAD1 Essential protein component of the DASH complex involved in spindle integrity and kinetochore function interacts with Duo1p and Dam1p localizes to intranuclear spindles and kinetochore
highly similar to uniprot|P38075 Saccharomyces cerevisiae YBR035C PDX3 Pyridoxine (pyridoxamine) phosphate oxidase has homologs in E. coli and Myxococcus xanthus transcription is under the general control of nitrogen metabolism
weakly similar to uniprot|Q99359 Saccharomyces cerevisiae YDR014W RAD61 Protein of unknown function mutation confers radiation sensitivity
highly similar to uniprot|Q12488 Saccharomyces cerevisiae YDR013W PSF1 Subunit of the GINS complex (Sld5p Psf1p Psf2p Psf3p) which binds to DNA replication origins and facilitates assembly of the DNA replication machinery
highly similar to uniprot|P38074 Saccharomyces cerevisiae YBR034C HMT1 Nuclear SAM-dependent mono- and asymmetric arginine dimethylating methyltransferase that modifies hnRNPs including Npl3p and Hrp1p thus facilitating nuclear export of these proteins required for viability of npl3 mutants
highly similar to uniprot|P49626 Saccharomyces cerevisiae YDR012W RPL4B Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl4A
similar to uniprot|P38222 Saccharomyces cerevisiae YBR030W Hypothetical ORF
similar to uniprot|P38221 Saccharomyces cerevisiae YBR029C CDS1 Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase) an enzyme that catalyzes that conversion of CTP phosphate into diphosphate CDP-diaclglyerol a critical step in the synthesis of all major yeast phospholipids
similar to uniprot|P38070 Saccharomyces cerevisiae YBR028C Hypothetical ORF
similar to uniprot|P38071 Saccharomyces cerevisiae YBR026C ETR1 2-enoyl thioester reductase member of the medium chain dehydrogenase/reductase family localized to in mitochondria where it has a probable role in fatty acid synthesis
similar to gnl|GLV|CAGL0I04774g Candida glabrata CAGL0I04774g and some similarites with YBR036C uniprot|P35206 Saccharomyces cerevisiae YBR036C CSG2 Endoplasmic reticulum membrane protein required for mannosylation of inositolphosphorylceramide and for growth at high calcium concentrations
highly similar to uniprot|P38219 Saccharomyces cerevisiae YBR025C Hypothetical ORF
similar to uniprot|P23833 Saccharomyces cerevisiae YBR037C
highly similar to uniprot|P14180 Saccharomyces cerevisiae YBR038W CHS2 Chitin synthase II requires activation from zymogenic form in order to catalyze the transfer of N-acetylglucosamine (GlcNAc) to chitin required for the synthesis of chitin in the primary septum during cytokinesis
similar to uniprot|P29465 Saccharomyces cerevisiae YBR023C CHS3 Chitin synthase III catalyzes the transfer of N-acetylglucosamine (GlcNAc) to chitin required for synthesis of the majority of cell wall chitin the chitin ring during bud emergence and spore wall chitosan
similar to uniprot|P38218 Saccharomyces cerevisiae YBR022W POA1 Phosphatase that is highly specific for ADP-ribose 1''-phosphate a tRNA splicing metabolite may have a role in regulation of tRNA splicing
similar to uniprot|P05316 YBR021W Saccharomyces cerevisiae FUR4 Uracil permease localized to the plasma membrane
similar to uniprot|P32568 Saccharomyces cerevisiae YDR011W SNQ2 ABC transporter
similar to uniprot|P13045 Saccharomyces cerevisiae YDR009W GAL3 Transcriptional regulator involved in activation of the GAL genes in response to galactose forms a complex with Gal80p and Gal4p to relieve inhibition by Gal80p binds galactose and ATP but does not have galactokinase activity and similar to YBR020W uniprot|P04385 Saccharomyces cerevisiae YBR020W GAL1 Galactokinase phosphorylates alpha-D-galactose to alpha-D-galactose-1- phosphate in the first step of galactose catabolism expression regulated by Gal4p
similar to uniprot|P04397 Saccharomyces cerevisiae YBR019C GAL10 UDP-glucose-4-epimerase catalyzes the interconversion of UDP-galactose and UDP-D-glucose in galactose metabolism also catalyzes the conversion of alpha-D-glucose or alpha-D-galactose to their beta-anomers
highly similar to uniprot|P08431 Saccharomyces cerevisiae YBR018C GAL7 Galactose-1-phosphate uridyl transferase synthesizes glucose-1-phosphate and UDP-galactose from UDP-D-glucose and alpha-D-galactose-1-phosphate in the second step of galactose catabolism
highly similar to uniprot|P40327 Saccharomyces cerevisiae YDL007W RPT2 One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates required for normal peptide hydrolysis by the core 20S particle
highly similar to uniprot|P35182 Saccharomyces cerevisiae YDL006W PTC1 Type 2C protein phosphatase (PP2C) inactivates the osmosensing MAPK cascade by dephosphorylating Hog1p mutation delays mitochondrial inheritance deletion reveals defects in precursor tRNA splicing sporulation and cell separation
weakly similar to uniprot|Q12124 Saccharomyces cerevisiae YDL005C MED2 RNA Polymerase II transcriptional regulation mediator Stoichiometric member of mediator complex
highly similar to gnl|GLV|KLLA0F14773g Kluyveromyces lactis KLLA0F14773g and similar to YDL004W uniprot|Q12165 Saccharomyces cerevisiae YDL004W ATP16 Delta subunit of the central stalk of mitochondrial F1F0 ATP synthase which is a large evolutionarily conserved enzyme complex required for ATP synthesis
similar to uniprot|Q05325 Saccharomyces cerevisiae YDL003W MCD1 Essential protein required for sister chromatid cohesion in mitosis and meiosis subunit of the cohesin complex expression is cell cycle regulated and peaks in S phase
similar to uniprot|P35194 Saccharomyces cerevisiae YBL004W UTP20 Possible snoRNA-binding protein based on computational analysis of large-scale protein-protein interaction data
similar to uniprot|Q03435 Saccharomyces cerevisiae YDL002C NHP10 Protein related to mammalian high mobility group proteins likely component of the INO80 complex which is an ATP-dependent chromatin-remodeling complex
similar to uniprot|Q05210 Saccharomyces cerevisiae YDL001W RMD1 Cytoplasmic protein required for sporulation
similar to uniprot|P04911 Saccharomyces cerevisiae YDR225W HTA1 One of two nearly identical (see also HTA2) histone H2A subtypes core histone required for chromatin assembly and chromosome function DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair acetylated by Nat4p and similar to YBL003C uniprot|P04912 Saccharomyces cerevisiae YBL003C HTA2 One of two nearly identical (see also HTA1) histone H2A subtypes; core histone required for chromatin assembly and chromosome function; DNA damage- dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p
similar to uniprot|P02293 Saccharomyces cerevisiae YDR224C HTB1 One of two nearly identical (see HTB2) histone H2B subtypes required for chromatin assembly and chromosome function Rad6p-Bre1p-Lge1p mediated ubiquitination regulates transcriptional activation meiotic DSB formation and H3 methylation and similar to YBL002W uniprot|P02294 Saccharomyces cerevisiae YBL002W HTB2 One of two nearly identical (see HTB2) histone H2B subtypes required for chromatin assembly and chromosome function; Rad6p-Bre1p-Lge1p mediated ubiquitination regulates transcriptional activation, meiotic DSB formation and H3 methylation
highly similar to uniprot|P35195 Saccharomyces cerevisiae YBL001C ECM15 Non-essential protein of unknown function likely exists as tetramer may be regulated by the binding of small-molecule ligands (possibly sulfate ions) may have a role in yeast cell-wall biogenesis
highly similar to uniprot|P32356 Saccharomyces cerevisiae YDR001C NTH1 Neutral trehalase degrades trehalose required for thermotolerance and may mediate resistance to other cellular stresses may be phosphorylated by Cdc28p
similar to uniprot|P41920 Saccharomyces cerevisiae YDR002W YRB1 Yeast Ran Binder #1 suppressor of FUS1 homolog of mouse HTF9a and human RanBP1 nuclear GTPase- activating protein for Ran
similar to uniprot|P35196 Saccharomyces cerevisiae YBR002C RER2 Cis-prenyltransferase involved in dolichol synthesis participates in endoplasmic reticulum (ER) protein sorting
highly similar to uniprot|P18900 Saccharomyces cerevisiae YBR003W COQ1 Hexaprenyl pyrophosphate synthetase catalyzes the first step in ubiquinone (coenzyme Q) biosynthesis
similar to uniprot|P38211 Saccharomyces cerevisiae YBR004C GPI18 Functional ortholog of human PIG-V which is a mannosyltransferase that transfers the second mannose in glycosylphosphatidylinositol biosynthesis the authentic non-tagged protein was localized to mitochondria
similar to uniprot|Q03446 Saccharomyces cerevisiae YDR003W
highly similar to uniprot|P38067 Saccharomyces cerevisiae YBR006W UGA2 Succinate semialdehyde dehydrogenase involved in the utilization of gamma-aminobutyrate (GABA) as a nitrogen source part of the 4-aminobutyrate and glutamate degradation pathways localized to the cytoplasm
similar to uniprot|P25301 Saccharomyces cerevisiae YDR004W RAD57 Protein that stimulates strand exchange by stabilizing the binding of Rad51p to single-stranded DNA involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis forms heterodimer with Rad55p
similar to uniprot|P41910 Saccharomyces cerevisiae YDR005C MAF1 Negative regulator of RNA polymerase III component of several signaling pathways that repress polymerase III transcription in response to changes in cellular environment targets the initiation factor TFIIIB
weakly similar to uniprot|P38213 Saccharomyces cerevisiae YBR007C DSF2
weakly similar to YDR006C, uniprot|P40317 Saccharomyces cerevisiae YDR006C (SOK1)
highly similar to uniprot|P61830 Saccharomyces cerevisiae YBR010W One of two identical histone H3 proteins
similar to uniprot|P00912 Saccharomyces cerevisiae YDR007W TRP1 Phosphoribosylanthranilate isomerase that catalyzes the third step in tryptophan biosynthesis in 2004 the sequence of TRP1 from strain S228C was updated by changing the previously annotated internal STOP (TAA) to serine (TCA)
highly similar to uniprot|P00817 Saccharomyces cerevisiae YBR011C IPP1 Cytoplasmic inorganic pyrophosphatase (PPase) catalyzes the rapid exchange of oxygens from Pi with water highly expressed and essential for viability active-site residues show identity to those from E. coli PPase
similar to uniprot|Q12157 Saccharomyces cerevisiae YDL008W APC11 Catalytic core subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors including mitotic cyclins during the metaphase/anaphase transition
weakly similar to Saccharomyces cerevisiae YDL010W Hypothetical ORF or YBR014C uniprot|P38068 Saccharomyces cerevisiae YBR014C Hypothetical ORF
similar to uniprot|P38069 Saccharomyces cerevisiae YBR015C MNN2 Alpha-1 2-mannosyltransferase responsible for addition of the first alpha-1 2-linked mannose to form the branches on the mannan backbone of oligosaccharides localizes to an early Golgi compartment
weakly similar to uniprot|P38216 Saccharomyces cerevisiae YBR016W
similar to uniprot|P32828 Saccharomyces cerevisiae YDL013W HEX3 Ring finger protein involved in the DNA damage response with possible recombination role genetically identified by synthetic lethality with SGS1 (DNA helicase) and TOP3 (DNA topoisomerase) sporulation role interacts with Slx8p and Lin1p
similar to uniprot|P15646 Saccharomyces cerevisiae YDL014W
similar to uniprot|Q99190 Saccharomyces cerevisiae YDL015C TSC13 ER protein involved in very long chain fatty acid synthesis
similar to uniprot|P06243 Saccharomyces cerevisiae YDL017W CDC7 DDK (Dbf4-dependent kinase) catalytic subunit required for firing origins and replication fork progression in mitosis through phosphorylation of Mcm2-7p complexes and Cdc45p kinase activity correlates with cyclical DBF4 expression
similar to uniprot|Q12403 Saccharomyces cerevisiae YDL018C
similar to uniprot|P32375 Saccharomyces cerevisiae YIR027C DAL1 Allantoinase converts allantoin to allantoate in the first step of allantoin degradation expression sensitive to nitrogen catabolite repression
highly similar to uniprot|P38217 Saccharomyces cerevisiae YBR017C KAP104 Transportin cytosolic karyopherin beta 2 involved in delivery of heterogeneous nuclear ribonucleoproteins to the nucleoplasm binds rg- nuclear localization signals on Nab2p and Hrp1p plays a role in cell-cycle progression
weakly similar to uniprot|P27637 Saccharomyces cerevisiae YAR014C BUD14 Protein involved in bud-site selection diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
highly similar to uniprot|P27616 Saccharomyces cerevisiae YAR015W ADE1 N-succinyl-5-aminoimidazole-4-carboxamide ribotide (SAICAR) synthetase required for 'de novo' purine nucleotide biosynthesis red pigment accumulates in mutant cells deprived of adenine
highly similar to uniprot|P22209 Saccharomyces cerevisiae YAR018C KIN3 Nonessential protein kinase with unknown cellular role
similar to uniprot|P27636 Saccharomyces cerevisiae YAR019C CDC15 Protein kinase of the Mitotic Exit Network that is localized to the spindle pole bodies at late anaphase promotes mitotic exit by directly switching on the kinase activity of Dbf2p
similar to uniprot|P80235 YAR035W Saccharomyces cerevisiae YAT1 Outer carnitine acetyltransferase mitochondrial
some similarities with uniprot|Q12451 Saccharomyces cerevisiae YDL019C OSH2 Member of an oxysterol-binding protein family with seven members in S. cerevisiae family members have overlapping redundant functions in sterol metabolism and collectively perform a function essential for viability
similar to uniprot|Q6B2F0 Saccharomyces cerevisiae YOL055C THI20 Hydroxymethylpyrimidine phosphate kinase involved in the last steps in thiamine biosynthesis member of a gene family with THI21 and THI22 functionally redundant with Thi21p
some similarities with uniprot|Q03465 Saccharomyces cerevisiae YDL020C RPN4 Transcription factor that stimulates expression of proteasome genes Rpn4p levels are in turn regulated by the 26S proteasome in a negative feedback control mechanism RPN4 is transcriptionally regulated by various stress responses
highly similar to uniprot|Q12326 Saccharomyces cerevisiae YOL056W GPM3 Homolog of Gpm1p phosphoglycerate mutase which converts 3-phosphoglycerate to 2-phosphoglycerate in glycolysis may be non-functional derivative of a gene duplication event
similar to uniprot|Q08225 Saccharomyces cerevisiae YOL057W Hypothetical ORF
highly similar to uniprot|P22768 Saccharomyces cerevisiae YOL058W ARG1 Arginosuccinate synthetase catalyzes the formation of L-argininosuccinate from citrulline and L-aspartate in the arginine biosynthesis pathway potential Cdc28p substrate
highly similar to uniprot|Q00055 Saccharomyces cerevisiae YDL022W GPD1 NAD-dependent glycerol-3-phosphate dehydrogenase key enzyme of glycerol synthesis essential for growth under osmotic stress expression regulated by high-osmolarity glycerol response pathway homolog of Gpd2p
highly similar to uniprot|Q12314 Saccharomyces cerevisiae YOR021C
highly similar to uniprot|P38910 Saccharomyces cerevisiae YOR020C HSP10 Mitochondrial matrix co-chaperonin that inhibits the ATPase activity of Hsp60p
weakly similar to uniprot|Q03338 Saccharomyces cerevisiae YDR473C PRP3 Splicing factor component of the U4/U6-U5 snRNP complex
some similarities with uniprot|Q99248 Saccharomyces cerevisiae YOR019W
similar to uniprot|Q03362 Saccharomyces cerevisiae YDR476C Hypothetical ORF
highly similar to uniprot|P06782 Saccharomyces cerevisiae YDR477W SNF1 Protein serine/threonine kinase required for release from glucose repression invertase expression sporulation and for expression of catabolite-repressed genes when glucose is limiting regulates Adr1p-dependent transcription primarily at the level of chromatin binding
similar to uniprot|P53687 Saccharomyces cerevisiae YOR025W HST3 Member of the Sir2 family of NAD()-dependent protein deacetylases involved along with Hst4p in telomeric silencing cell cycle progression radiation resistance genomic stability and short-chain fatty acid metabolism
some similarities with uniprot|P40993 Saccharomyces cerevisiae YDR478W SNM1 Subunit of RNase MRP which cleaves pre-rRNA not shared between Rnase MRP and nuclear Rnase P in contrast to all other Rnase MRP protein subunits binds to the NME1 RNA subunit of Rnase MRP
similar to uniprot|Q03370 Saccharomyces cerevisiae YDR479C PEX29 Peroxisomal integral membrane protein involved in regulation of peroxisome size and number genetic interactions suggest that Pex28p and Pex29p act at steps upstream of those mediated by Pex30p Pex31p and Pex32p
similar to uniprot|P26449 Saccharomyces cerevisiae YOR026W BUB3 Kinetochore checkpoint WD40 repeat protein that localizes to kinetochores during prophase and metaphase delays anaphase in the presence of unattached kinetochores forms complexes with Mad1p-Bub1p and with Cdc20p binds Mad2p and Mad3p
similar to uniprot|Q07015 Saccharomyces cerevisiae YDR257C SET7 Nuclear protein that contains a SET-domain which have been shown to mediate methyltransferase activity in other proteins
highly similar to uniprot|P15705 Saccharomyces cerevisiae YOR027W STI1 Heat shock protein also induced by canavanine and entry into stationary phase
highly similar to uniprot|Q05016 Saccharomyces cerevisiae YMR226C NADP()-dependent dehydrogenase acts on serine L-allo-threonine and other 3-hydroxy acids
similar to uniprot|Q12012 Saccharomyces cerevisiae YOR289W Hypothetical ORF
similar to uniprot|Q12404 Saccharomyces cerevisiae YOR288C MPD1 Member of the protein disulfide isomerase (PDI) family overexpression suppresses the defect in maturation of carboxypeptidase Y and defects in other essential Pdi1p functions caused by PDI1 deletion
mitochondrial 54S ribosomal protein YmL44
similar to uniprot|P19956 Saccharomyces cerevisiae YMR225C MRPL44 Mitochondrial ribosomal protein of the large subunit
similar to uniprot|Q12481 Saccharomyces cerevisiae YOR287C Protein required for cell viability
similar to uniprot|Q08742 Saccharomyces cerevisiae YOR286W FMP31 The authentic non-tagged protein was localized to the mitochondria
weakly similar to uniprot|Q12305 Saccharomyces cerevisiae YOR285W Hypothetical ORF
similar to uniprot|Q12040 Saccharomyces cerevisiae YOR283W Hypothetical ORF
similar to uniprot|P32829 Saccharomyces cerevisiae YMR224C MRE11 Subunit of a complex with Rad50p and Xrs2p (RMX complex) that functions in repair of DNA double-strand breaks and in telomere stability exhibits nuclease activity that appears to be required for RMX function widely conserved
similar to uniprot|Q12017 Saccharomyces cerevisiae YOR281C
similar to uniprot|P50102 Saccharomyces cerevisiae YMR223W UBP8 Ubiquitin-specific protease that is a component of the SAGA (Spt-Ada-Gcn5-Acetyltransferase) acetylation complex required for SAGA-mediated deubiquitination of histone H2B
similar to uniprot|Q05015 Saccharomyces cerevisiae YMR222C and similar to uniprot|Q99369 Saccharomyces cerevisiae YOR280C
similar to Saccharomyces cerevisiae and to YMR222C uniprot|Q05015 Saccharomyces cerevisiae FSH2 Serine hydrolase
similar to uniprot|Q04991 Saccharomyces cerevisiae YMR221C FMP42 The authentic non-tagged protein was localized to the mitochondria
weakly similar to uniprot|Q12192 Saccharomyces cerevisiae YOR279C RFM1 DNA-binding protein required for repression of middle sporulation genes specificity factor that directs the Hst1p histone deacetylase to some of the promoters regulated by Sum1p
similar to uniprot|P24521 Saccharomyces cerevisiae YMR220W ERG8 Phosphomevalonate kinase an essential cytosolic enzyme that acts in the biosynthesis of isoprenoids and sterols including ergosterol from mevalonate
some similarities with uniprot|Q03661 Saccharomyces cerevisiae YMR219W ESC1 Protein localized to the nuclear periphery involved in telomeric silencing interacts with PAD4-domain of Sir4p
similar to uniprot|Q03660 Saccharomyces cerevisiae YMR218C TRS130 Component of the targeting complex (TRAPP) involved in ER to Golgi membrane traffic
similar to uniprot|P06174 Saccharomyces cerevisiae YOR278W HEM4 Uroporphyrinogen III synthase catalyzes the conversion of hydroxymethylbilane to uroporphyrinogen III the fourth step in the heme biosynthetic pathway
highly similar to uniprot|P38625 Saccharomyces cerevisiae YMR217W GUA1 GMP synthase an enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP) transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation
similar to uniprot|Q03656 Saccharomyces cerevisiae YMR216C
similar to uniprot|Q03655 Saccharomyces cerevisiae YMR215W GAS3 Putative 1,3-beta-glucanosyltransferase has similarity to Gas1p localizes to the cell wall
similar to uniprot|P25303 Saccharomyces cerevisiae YMR214W SCJ1 dnaJ homolog
similar to uniprot|P12962 Saccharomyces cerevisiae YOR276W CAF20 Phosphoprotein of the mRNA cap-binding complex involved in translational control repressor of cap-dependent translation initiation competes with eIF4G for binding to eIF4E
highly similar to uniprot|P32468 Saccharomyces cerevisiae YHR107C CDC12 Component of the septin ring of the mother-bud neck that is required for cytokinesis septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane and they comprise the 10nm filaments seen with EM
highly similar to uniprot|P29509 YDR353W Saccharomyces cerevisiae TRR1 Thioredoxin reductase
similar to gnl|GLV|CAGL0I01144g Candida glabrata CAGL0I01144g and some similarities with uniprot|P38815 Saccharomyces cerevisiae YHR105W YPT35 Hypothetical ORF
highly similar to uniprot|P38715 Saccharomyces cerevisiae YHR104W GRE3 Aldose reductase involved in methylglyoxal d-xylose and arabinose metabolism stress induced (osmotic ionic oxidative heat shock starvation and heavy metals) regulated by the HOG pathway
similar to uniprot|Q06328 YDR352w Saccharomyces cerevisiae Hypothetical ORF
similar to uniprot|P38814 YHR103W Saccharomyces cerevisiae SBE Protein involved in the transport of cell wall components from the Golgi to the cell surface
weakly similar to uniprot|P38692 Saccharomyces cerevisiae YHR102W KIC1 Protein kinase of the PAK/Ste20 kinase family required for cell integrity possibly through regulating 1 6-beta-glucan levels in the wall physically interacts with Cdc31p (centrin) which is a component of the spindle pole body
weakly similar to uniprot|P50273 YDR350C Saccharomyces cerevisiae CM10 Mitochondrial inner membrane protein required for assembly of the F0 sector of mitochondrial F1F0 ATP synthase
similar to uniprot|P38813 Saccharomyces cerevisiae YHR101C BIG1 Integral membrane protein of the endoplasmic reticulum required for normal content of cell wall beta-1 6-glucan
similar to uniprot|P38812 Saccharomyces cerevisiae YHR100C Hypothetical ORF
highly similar to uniprot|P38811 Saccharomyces cerevisiae YHR099W TRA1 Histone acetyltransferase component putative ortholog of human TRRAP which is an essential cofactor of c-Myc
similar to uniprot|Q66RD4 Saccharomyces cerevisiae YDR349C YPS7 Putative GPI-anchored aspartic protease located in the cytoplasm and endoplasmic reticulum
similar to uniprot|P38810 Saccharomyces cerevisiae YHR098C SFB3 Member of the Sec24p family forms a complex with Sec23p that is involved in sorting of Pma1p into COPII vesicles peripheral ER membrane protein potential Cdc28p substrate
similar to gnl|GLV|KLLA0F22154g Kluyveromyces lactis KLLA0F22154g and some similarites with YDR348C uniprot|Q66RD5 Saccharomyces cerevisiae YDR348C Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and bud neck potential Cdc28p substrate
mitochondrial 37S ribosomal protein MRP1
similar to uniprot|P10662 Saccharomyces cerevisiae YDR347W MRP1 Mitochondrial ribosomal protein of the small subunit MRP1 exhibits genetic interactions with PET122 encoding a COX3-specific translational activator and with PET123 encoding a small subunit mitochondrial ribosomal protein
similar to uniprot|Q05515 Saccharomyces cerevisiae YDR346C SVF1 Protein with a potential role in cell survival pathways required for the diauxic growth shift expression in mammalian cells increases survival under conditions inducing apoptosis
highly similar to uniprot|P39003 Saccharomyces cerevisiae YDR343C HXT6 High-affinity glucose transporter of the major facilitator superfamily nearly identical to Hxt7p expressed at high basal levels relative to other HXTs repression of expression by high glucose requires SNF3
highly similar to uniprot|Q05506 Saccharomyces cerevisiae YDR341C Cytoplasmic arginyl-tRNA synthetase
highly similar to uniprot|Q05498 Saccharomyces cerevisiae YDR339C Protein required for cell viability
similar to uniprot|P38806 Saccharomyces cerevisiae YHR090C YNG2 Yeast homolog of mammalian Ing1 NuA4 histone acetyltransferase complex component
similar to uniprot|Q05497 Saccharomyces cerevisiae YDR338C Hypothetical ORF
weakly similar to uniprot|P08465 Saccharomyces cerevisiae YNL277W
mitochondrial 37S ribosomal protein MRPS28
similar to uniprot|P21771 Saccharomyces cerevisiae YDR337W MRPS28 Mitochondrial ribosomal protein of the small subunit
some similarities with uniprot|P28007 Saccharomyces cerevisiae YHR089C GAR1 Protein component of the H/ACA snoRNP pseudouridylase complex involved in the modification and cleavage of the 18S pre-rRNA
similar to uniprot|Q05473 Saccharomyces cerevisiae YDR336W Hypothetical ORF
highly similar to uniprot|P52918 Saccharomyces cerevisiae YDR335W MSN5 Karyopherin involved in nuclear import and export shown to be responsible for nuclear import of replication protein A and for export of several proteins including Swi6p Far1p and Pho4p cargo dissociation involves binding to RanGTP
highly similar to uniprot|P38805 Saccharomyces cerevisiae YHR088W RPF1 Nucleolar protein involved in the assembly of the large ribosomal subunit contains a sigma(70)-like motif which is thought to bind RNA
similar to uniprot|P38804 Saccharomyces cerevisiae YHR087W Hypothetical ORF
some similarities with gnl|GLV|CAGL0M01188g Candida glabrata CAGL0M01188g and some similarites with uniprot|Q05471 Saccharomyces cerevisiae YDR334W SWR1 Swi2/Snf2-related ATPase component of the SWR1 complex required for the incorporation of Htz1p into chromatin
some similarities with uniprot|Q00539 Saccharomyces cerevisiae YHR086W NAM8 RNA binding protein component of the U1 snRNP protein mutants are defective in meiotic recombination and in formation of viable spores involved in the formation of DSBs through meiosis-specific splicing of MER2 pre-mRNA
similar to uniprot|P30775 Saccharomyces cerevisiae YGL143C MRF1 Mitochondrial polypeptide chain release factor involved in stop codon recognition and hydrolysis of the peptidyl-tRNA bond during mitochondrial translation lack of MRF1 causes mitochondrial genome instability
highly similar to uniprot|P06242 Saccharomyces cerevisiae YDL108W KIN28 Serine/threonine protein kinase subunit of the transcription factor TFIIH involved in transcription initiation at RNA polymerase II promoters
similar to uniprot|P40990 Saccharomyces cerevisiae YDL107W MSS2 Peripherally bound inner membrane protein of the mitochondrial matrix required for export of C-terminal tail of Cox2p through the inner membrane
similar to uniprot|P30777 Saccharomyces cerevisiae YGL142C GPI10 Integral membrane protein involved in glycosylphosphatidylinositol (GPI) anchor synthesis putative alpha 1 2 mannosyltransferase required for addition of the third mannose onto the GPI core structure human PIG-Bp is a functional homolog
similar to uniprot|P53119 Saccharomyces cerevisiae YGL141W
similar to uniprot|P32343 Saccharomyces cerevisiae YKL124W SSH4 Suppressor of SHR3 confers leflunomide resistance when overexpressed (putative) involved in ER functions
similar to uniprot|P07269 Saccharomyces cerevisiae YDL106C PHO2 Homeobox transcription factor regulatory targets include genes involved in phosphate metabolism binds cooperatively with Pho4p to the PHO5 promoter phosphorylation of Pho2p facilitates interaction with Pho4p
similar to uniprot|P47771 Saccharomyces cerevisiae YMR170c ALD5 and similar to uniprot|P54114 Saccharomyces cerevisiae YMR169c ALD4
similar to uniprot|P47771 Saccharomyces cerevisiae YMR170C ALD2 Cytosolic aldehyde dehydrogenase that uses NAD as the preferred coenzyme expression is induced in response to high osmotic stress
similar to uniprot|P40969 Saccharomyces cerevisiae YMR168C CEP3 Essential kinetochore protein component of the CBF3 complex that binds the CDEIII region of the centromere contains an N-terminal Zn2Cys6 type zinc finger domain a C-terminal acidic domain and a putative coiled coil dimerization domain
similar to uniprot|Q2I041 Saccharomyces cerevisiae YMR167W MLH1 Protein required for mismatch repair in mitosis and meiosis postmeiotic segregation and spore viability forms a complex with Pms1p and Msh2p to repair mismatched DNA human homolog is associated with hereditary non-polyposis colon cancer
similar to uniprot|P43124 Saccharomyces cerevisiae YDL105W NSE4 Nuclear protein that plays a role in the function of the Smc5p-Rhc18p complex
similar to uniprot|P43122 Saccharomyces cerevisiae YDL104C
similar to uniprot|Q03829 Saccharomyces cerevisiae YMR166C
similar to uniprot|P32567 Saccharomyces cerevisiae YMR165C SMP2 Protein involved in respiration and plasmid maintenance
some similarities with uniprot|Q03825 Saccharomyces cerevisiae YMR164C
weakly similar to uniprot|Q03824 Saccharomyces cerevisiae YMR163C Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
highly similar to gnl|GLV|CAGL0L07370g Candida glabrata CAGL0L07370g and similar to uniprot|P43123 Saccharomyces cerevisiae YDL103C QRI1 UDP-N-acetylglucosamine pyrophosphorylase catalyzes the formation of UDP-N-acetylglucosamine (UDP-GlcNAc) which is important in cell wall biosynthesis protein N- glycosylation and GPI anchor biosynthesis
similar to uniprot|Q12674 Saccharomyces cerevisiae YMR162C DNF3 Non-essential P-type ATPase that is a potential aminophospholipid translocase localizes to the trans-Golgi likely involved in protein transport
similar to uniprot|P48353 Saccharomyces cerevisiae YMR161W
highly similar to uniprot|P15436 Saccharomyces cerevisiae YDL102W CDC2 Catalytic subunit of DNA polymerase delta required for chromosomal DNA replication during mitosis and meiosis intragenic recombination repair of double strand DNA breaks and DNA replication during nucleotide excision repair (NER)
highly similar to uniprot|P39009 Saccharomyces cerevisiae YDL101C DUN1 Cell-cycle checkpoint serine-threonine kinase required for DNA damage-induced transcription of certain target genes phosphorylation of Rad55p and Sml1p and transient G2/M arrest after DNA damage also regulates postreplicative DNA repair
similar to uniprot|Q03823 Saccharomyces cerevisiae YMR160W Hypothetical ORF
similar to uniprot|Q03818 Saccharomyces cerevisiae YMR159C ATG16 Protein that interacts with the Atg12p-Atg5p conjugate during formation of the pre-autophagosomal structure essential for autophagy
highly similar to uniprot|Q12154 Saccharomyces cerevisiae YDL100C ARR4 ATPase involved in resistance to heat and metal stress active as a dimer normally localized to the cytosol but appears to localize to late endosomes under stress conditions
weakly similar to uniprot|Q12191 Saccharomyces cerevisiae YDL099W Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
mitochondrial 37S ribosomal protein MRPS8
highly similar to uniprot|Q03799 Saccharomyces cerevisiae YMR158W MRPS8 Mitochondrial ribosomal protein of the small subunit
similar to uniprot|Q03798 Saccharomyces cerevisiae YMR157C FMP39 The authentic non-tagged protein was localized to the mitochondria
similar to uniprot|Q12368 Saccharomyces cerevisiae YDL098C SNU23 23 kD U4/U6.U5 snRNP associated protein Putative RNA binding zinc finger protein
similar to uniprot|Q03796 Saccharomyces cerevisiae YMR156C TPP1 DNA 3'-phosphatase that functions in the repair of endogenous DNA damage functionally redundant with Apn1p and Apn2p
highly similar to uniprot|Q12377 Saccharomyces cerevisiae YDL097C RPN6 Essential non-ATPase regulatory subunit of the 26S proteasome lid required for the assembly and activity of the 26S proteasome the human homolog (S9 protein) partially rescues Rpn6p depletion
similar to uniprot|P33775 Saccharomyces cerevisiae YDL095W PMT1 Transfers mannose residues from dolichyl phosphate-D-mannose to specific serine/threonine residues of proteins in the secretory pathway acts in complex with Pmt2p dolichyl phosphate-D-mannose:protein O-D-mannosyltransferase
some similarities with uniprot|Q03795 Saccharomyces cerevisiae YMR155W Hypothetical ORF
similar to uniprot|P38985 Saccharomyces cerevisiae YDL092W SRP14 Signal recognition particle subunit
similar to uniprot|Q12229 YDL091c Saccharomyces cerevisiae UBX3 UBX domain-containing protein that interacts with Cdc48p
similar to uniprot|P22007 Saccharomyces cerevisiae YDL090C RAM1 essential for processing of ras proteins beta subunit of farnesyltransferase
similar to uniprot|Q03792 Saccharomyces cerevisiae YMR154C
weakly similar to uniprot|Q12066 Saccharomyces cerevisiae YDL089W Protein of unknown function interacts with meiotic division protein Csm1p green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery potential Cdc28p substrate
similar to gnl|GLV|KLLA0F07227g Kluyveromyces lactis KLLA0F07227g and weakly similar to uniprot|Q05166 Saccharomyces cerevisiae YDL088C ASM4 Nuclear pore complex subunit part of a subcomplex also containing Nup53p Nup170p and Pse1p
similar to uniprot|P28625 Saccharomyces cerevisiae YMR152W YIM1 Mitochondrial inner membrane protease
highly similar to uniprot|Q07508 Saccharomyces cerevisiae YDL087C LUC7 Essential protein associated with the U1 snRNP complex splicing factor involved in recognition of 5' splice site
similar to uniprot|Q03085 Saccharomyces cerevisiae YPL033C Hypothetical ORF
similar to uniprot|P28627 Saccharomyces cerevisiae YMR150c IMP1 protease, mitochondrial
similar to uniprot|Q02795 Saccharomyces cerevisiae YMR149W SWP1 oligosaccharyl transferase glycoprotein complex delta subunit
some similarities with uniprot|P40219 Saccharomyces cerevisiae YMR148W Hypothetical ORF
some similarities with uniprot|P40218 Saccharomyces cerevisiae YMR147W Hypothetical ORF
some similarities with uniprot|Q03083 Saccharomyces cerevisiae YPL034W Hypothetical ORF
similar to uniprot|Q07505 Saccharomyces cerevisiae YDL086W
highly similar to uniprot|P40217 Saccharomyces cerevisiae YMR146C TIF34 Subunit of the core complex of translation initiation factor 3(eIF3) which is essential for translation
highly similar to uniprot|Q08911 Saccharomyces cerevisiae YOR388C FDH1 NAD()-dependent formate dehydrogenase may protect cells from exogenous formate
similar to uniprot|P40215 Saccharomyces cerevisiae YMR145C NDE1 Mitochondrial external NADH dehydrogenase
highly similar to uniprot|Q07478 Saccharomyces cerevisiae YDL084W SUB2 Suppresses the cold-sensitive snRNP biogenesis brr1-1 mutation RNA helicase
some similarities with uniprot|P40214 Saccharomyces cerevisiae YMR144W Hypothetical ORF
highly similar to uniprot|P40213 Saccharomyces cerevisiae YMR143w RPS16A or uniprot|P40213 Saccharomyces cerevisiae YDL083c RPS16B
highly similar to uniprot|Q12690 Saccharomyces cerevisiae YDL082w RPL13A ribosomal protein or uniprot|P40212 Saccharomyces cerevisiae YMR142c RPL13B
highly similar to uniprot|P05318 Saccharomyces cerevisiae YDL081C RPP1A Ribosomal protein P1 alpha a component of the ribosomal stalk which is involved in the interaction between translational elongation factors and the ribosome accumulation of P1 in the cytoplasm is regulated by phosphorylation and interaction with the P2 stalk component
similar to uniprot|P40210 Saccharomyces cerevisiae YMR140W SIP5 Sip5p facilitates the interaction between the Glc7p phosphatase and the Snf1p kinase
weakly similar to uniprot|P18544 Saccharomyces cerevisiae YOL140W ARG8 Acetylornithine aminotransferase catalyzes the fourth step in the biosynthesis of the arginine precursor ornithine
similar to uniprot|Q07471 Saccharomyces cerevisiae YDL080C THI3 Probable decarboxylase required for expression of enzymes involved in thiamine biosynthesis may have a role in catabolism of amino acids to long-chain and complex alcohols
highly similar to uniprot|P38615 Saccharomyces cerevisiae YMR139W RIM11 Protein kinase required for signal transduction during entry into meiosis
similar to uniprot|P32419 Saccharomyces cerevisiae YDL078C MDH3 Cytoplasmic malate dehydrogenase catalyzes interconversion of malate and oxaloacetate involved in the glyoxylate cycle
similar to uniprot|P39110 Saccharomyces cerevisiae YMR138W CIN4 GTP-binding protein involved in beta-tubulin (Tub2p) folding isolated as mutant with increased chromosome loss and sensitivity to benomyl
similar to uniprot|Q759M6 Ashbya gossypii ADR250C ADR250Cp and weakly similar to YMR137C uniprot|P30620 Saccharomyces cerevisiae YMR137C PSO2 Required for a post-incision step in the repair of DNA single and double-strand breaks that result from interstrand crosslinks produced by a variety of mono- and bi-functional psoralen derivatives induced by UV-irradiation
weakly similar to uniprot|P40209 Saccharomyces cerevisiae YMR136W GAT2
similar to uniprot|P40208 Saccharomyces cerevisiae YMR135C GID8 Protein of unknown function involved in proteasome-dependent catabolite inactivation of fructose-1 6-bisphosphatase contains LisH and CTLH domains like Vid30p
similar to uniprot|P40207 Saccharomyces cerevisiae YMR134W Protein required for cell viability
some similarities with uniprot|Q07988 Saccharomyces cerevisiae YLR040C Hypothetical ORF
some similarities with uniprot|P32841 Saccharomyces cerevisiae YMR133W REC114 Protein involved in early stages of meiotic recombination
similar to uniprot|P40206 Saccharomyces cerevisiae YMR132C JLP2 Hypothetical ORF
highly similar to uniprot|Q04225 Saccharomyces cerevisiae YMR131C RRB1 RiboSome Assembly 2
similar to uniprot|P40395 Saccharomyces cerevisiae YLR039C RIC1 Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleotide exchange on Ypt6p involved in transcription of ribosomal protein genes and ribosomal RNA
highly similar to uniprot|Q01519 Saccharomyces cerevisiae YLR038C COX12 Subunit VIb of cytochrome c oxidase which is the terminal member of the mitochondrial inner membrane electron transport chain required for assembly of fully active cytochrome c oxidase but not required for activity after assembly
similar to uniprot|Q04223 Saccharomyces cerevisiae YMR130W Hypothetical ORF
some similarities with uniprot|Q07980 Saccharomyces cerevisiae YLR035C MLH2 Protein required for DNA mismatch repair in mitosis and meiosis involved in the repair of mutational intermediates forms a complex with Pms1p and Msh1p to repair mismatched DNA
similar to uniprot|P39685 Saccharomyces cerevisiae YMR129W POM152 Nuclear pore membrane glycoprotein may be involved in duplication of nuclear pores and nuclear pore complexes during S-phase
highly similar to uniprot|Q12078 Saccharomyces cerevisiae YLR034C SMF3 Putative metal transporter Nramp homolog homolog of SMF1 and SMF2
similar to uniprot|Q07979 Saccharomyces cerevisiae YLR033W RSC58
similar to uniprot|Q04217 Saccharomyces cerevisiae YMR128W ECM16 Essential DEAH-box ATP-dependent RNA helicase specific to the U3 snoRNP predominantly nucleolar in distribution required for 18S rRNA synthesis
similar to uniprot|P40963 Saccharomyces cerevisiae YMR127C SAS2 Histone acetyltransferase (HAT) catalytic subunit of the SAS complex (Sas2p-Sas4p-Sas5p) which acetylates free histones and nucleosomes and regulates transcriptional silencing member of the MYSTacetyltransferase family
similar to uniprot|P32849 Saccharomyces cerevisiae YLR032W RAD5 Single-stranded DNA-dependent ATPase involved in postreplication repair contains RING finger domain
similar to uniprot|Q04216 Saccharomyces cerevisiae YMR126C DLT1 Protein of unknown function deletion causes sensitivity to thermal stress
similar to uniprot|P34160 Saccharomyces cerevisiae YMR125W STO1 Large subunit of the nuclear mRNA cap-binding protein complex interacts with Npl3p to carry poly(A) mRNA from the nucleus to the cytoplasm also involved in mRNA degradation in the nucleus orthologous to mammalian CBP80
weakly similar to uniprot|P39523 Saccharomyces cerevisiae YMR124W Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cell periphery cytoplasm bud and bud neck
similar to uniprot|Q03880 Saccharomyces cerevisiae YMR123W PKR1 Protein of unknown function overproduction confers resistance to Pichia farinosa killer toxin
some similarities with uniprot|Q3E842 Saccharomyces cerevisiae YMR122W-A
highly similar to uniprot|P54780 Saccharomyces cerevisiae RPL15B and to uniprot|P05748 Saccharomyces cerevisiae YLR029C RPL15A
highly similar to uniprot|P38009 Saccharomyces cerevisiae YMR120C ADE17 Enzyme of 'de novo' purine biosynthesis containing both 5-aminoimidazole-4-carboxamide ribonucleotide transformylase and inosine monophosphate cyclohydrolase activities isozyme of Ade16p ade16 ade17 mutants require adenine and histidine
similar to uniprot|P54074 Saccharomyces cerevisiae YMR119W ASI1 Putative integral membrane E3 ubiquitin ligase genetic interactions suggest a role in negative regulation of amino acid uptake
highly similar to uniprot|P32473 Saccharomyces cerevisiae YBR221C
similar to uniprot|P38318 Saccharomyces cerevisiae YBR220C Hypothetical ORF
weakly similar to uniprot|P53012 Saccharomyces cerevisiae YGL126W SCS3 Protein required for inositol prototrophy
similar to uniprot|P38633 Saccharomyces cerevisiae YGL127C SOH1 Protein with sequence similarity to RNA polymerases; interacts with a DNA repair protein, Rad5p, in the two-hybrid system; may provide a link between recombination in direct repeats and transcription
similar to uniprot|P32501 Saccharomyces cerevisiae YDR211W GCD6 Catalytic epsilon subunit of the translation initiation factor eIF2B the guanine-nucleotide exchange factor for eIF2 activity subsequently regulated by phosphorylated eIF2 first identified as a negative regulator of GCN4 expression
highly similar to uniprot|P19073 Saccharomyces cerevisiae YLR229C CDC42 Small rho-like GTPase essential for establishment and maintenance of cell polarity mutants have defects in the organization of actin and septins
highly similar to uniprot|P12612 Saccharomyces cerevisiae YDR212W TCP1 tailless complex polypeptide 1 chaperonin subunit alpha
similar to gnl|GLV|KLLA0A04169g Kluyveromyces lactis KLLA0A04169g and some similarites with YDR213W uniprot|Q12151 Saccharomyces cerevisiae YDR213W UPC2 involved in sterol uptake zinc finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type
similar to uniprot|Q7LIE3 Saccharomyces cerevisiae YDR214W AHA1 Activator of Heat Shock Protein 90 ATPase
similar to uniprot|P07248 Saccharomyces cerevisiae YDR216W ADR1 Positive transcriptional regulator controls the expression of ADH2 peroxisomal protein genes and genes required for ethanol glycerol and fatty acid utilization
weakly similar to uniprot|P14737 Saccharomyces cerevisiae YDR217C RAD9 DNA damage-dependent checkpoint protein required for cell-cycle arrest in G1/S intra-S and G2/M transmits checkpoint signal by activating Rad53p and Chk1p hyperphosphorylated by Mec1p and Tel1p potential Cdc28p substrate
weakly similar to uniprot|Q05955 Saccharomyces cerevisiae YLR227C ADY4 Component of the meiotic outer plaque a membrane-organizing center that assembles on the cytoplasmic face of the spindle pole body during meiosis II and triggers the formation of the prospore membrane
similar to uniprot|Q04921 Saccharomyces cerevisiae YDR218C SPR28 Septin-related protein expressed during sporulation
similar to uniprot|Q05949 Saccharomyces cerevisiae YLR226W BUR2 Cyclin for the Sgv1p (Bur1p) protein kinase Sgv1p and Bur2p comprise a CDK-cyclin complex involved in transcriptional regulation through its phosphorylation of the carboxy-terminal domain of the largest subunit of RNA polymerase II
weakly similar to uniprot|Q04922 Saccharomyces cerevisiae YDR219C Hypothetical ORF
weakly similar to uniprot|Q04924 Saccharomyces cerevisiae YDR221W Hypothetical ORF
similar to uniprot|Q05948 Saccharomyces cerevisiae YLR225C Hypothetical ORF
weakly similar to uniprot|Q05947 Saccharomyces cerevisiae YLR224W Hypothetical ORF
weakly similar to uniprot|P39520 Saccharomyces cerevisiae YLR223C IFH1 Essential protein with a highly acidic N-terminal domain IFH1 exhibits genetic interactions with FHL1 overexpression interferes with silencing at telomeres and HM loci potential Cdc28p substrate
highly similar to uniprot|Q05946 Saccharomyces cerevisiae YLR222C UTP13 Nucleolar protein component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
some similarities with uniprot|Q05942 Saccharomyces cerevisiae YLR221C RSA3 Protein with a likely role in ribosomal maturation required for accumulation of wild-type levels of large (60S) ribosomal subunits binds to the helicase Dbp6p in pre-60S ribosomal particles in the nucleolus
highly similar to uniprot|Q74ZL6 Ashbya gossypii AGR182C AGR182Cp and similar to YLR220W uniprot|P47818 Saccharomyces cerevisiae YLR220W CCC1 Functions in the homeostasis of both calcium and manganese ions Possible transmembrane Ca2 transporter
some similarities with uniprot|Q05812 Saccharomyces cerevisiae YLR219W MSC3 Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cell periphery msc3 mutants are defective in directing meiotic recombination events to homologous chromatids
some similarities with uniprot|P11978 Saccharomyces cerevisiae YDR227W SIR4 Silent information regulator that together with SIR2 and SIR3 is involved in assembly of silent chromatin domains at telomeres and the silent mating-type loci potentially phosphorylated by Cdc28p some alleles of SIR4 prolong lifespan
some similarities with gnl|GLV|DEHA0A12507g Debaryomyces hansenii DEHA0A12507g
similar to uniprot|P39081 Saccharomyces cerevisiae YDR228C PCF11 mRNA 3' end processing factor essential component of cleavage and polyadenylation factor IA (CF IA) involved in pre-mRNA 3' end processing and in transcription termination binds C-terminal domain of largest subunit of RNA pol II (Rpo21p)
highly similar to uniprot|P38988 Saccharomyces cerevisiae YDL198C GGC1 Mitochondrial GTP/GDP transporter essential for mitochondrial genome maintenance has a role in mitochondrial iron transport member of the mitochondrial carrier family (putative) mitochondrial carrier protein
similar to uniprot|P26188 Saccharomyces cerevisiae YDL200c, DNA repair methyltransferase (6-O-methylguanine-DNA methylase) involved in protection against DNA alkylation damage
highly similar to uniprot|Q12009 Saccharomyces cerevisiae YDL201W TRM8 Subunit of a tRNA methyltransferase complex composed of Trm8p and Trm82p that catalyzes 7-methylguanosine modification of tRNA
mitochondrial 54S ribosomal protein YmL11
similar to uniprot|P36521 Saccharomyces cerevisiae YDL202W MRPL11 Mitochondrial ribosomal protein of the large subunit
similar to uniprot|Q04934 Saccharomyces cerevisiae YDR229W IVY1 Phospholipid-binding protein that interacts with both Ypt7p and Vps33p may partially counteract the action of Vps33p and vice versa localizes to the rim of the vacuole as cells approach stationary phase
similar to uniprot|Q04935 Saccharomyces cerevisiae YDR231C COX20 Mitochondrial inner membrane protein required for proteolytic processing of Cox2p and its assembly into cytochrome c oxidase
similar to uniprot|Q07622 Saccharomyces cerevisiae YDL203C Hypothetical ORF
highly similar to gnl|GLV|KLLA0C15059g Kluyveromyces lactis KLLA0C15059g and similar to YDR232W uniprot|P09950 Saccharomyces cerevisiae YDR232W HEM1 5- aminolevulinate synthase catalyzes the first step in the heme biosynthetic pathway an N-terminal signal sequence is required for localization to the mitochondrial matrix expression is regulated by Hap2p-Hap3p
some similarities with uniprot|Q04947 Saccharomyces cerevisiae YDR233C RTN1 reticulon gene member of the RTNLA (reticulon-like A) subfamily
similar to uniprot|P49367 Saccharomyces cerevisiae YDR234W LYS4 Homoaconitase catalyzes the conversion of homocitrate to homoisocitrate which is a step in the lysine biosynthesis pathway
similar to uniprot|P28789 Saccharomyces cerevisiae YDL205C HEM3 Phorphobilinogen deaminase catalyzes the conversion of 4-porphobilinogen to hydroxymethylbilane the third step in the heme biosynthetic pathway localizes to both the cytoplasm and nucleus expression is regulated by Hap2p-Hap3p
similar to uniprot|Q03776 Saccharomyces cerevisiae YDR235W PRP42 U1 snRNP protein involved in splicing required for U1 snRNP biogenesis contains multiple tetriatricopeptide repeats
similar to gnl|GLV|KLLA0C15191g Kluyveromyces lactis KLLA0C15191g and weakly similar to uniprot|Q12424 Saccharomyces cerevisiae YDL206W Hypothetical ORF
similar to uniprot|Q03778 Saccharomyces cerevisiae YDR236C FMN1 Riboflavin kinase phosphorylates riboflavin to form riboflavin monophosphate (FMN) which is a necessary cofactor for many enzymes localizes to microsomes and to the mitochondrial inner membrane
some similarities with uniprot|Q12315 Saccharomyces cerevisiae YDL207W GLE1 Cytoplasmic nucleoporin required for polyadenylated RNA export but not for protein import component of Nup82p nuclear pore subcomplex contains a nuclear export signal
mitochondrial 54S ribosomal protein YmL7/YmL5
similar to uniprot|P36519 Saccharomyces cerevisiae YDR237W MRPL7 Mitochondrial ribosomal protein of the large subunit
mitochondrial 37S ribosomal protein RSM27
similar to uniprot|P53305 Saccharomyces cerevisiae YGR215W RSM27 Mitochondrial ribosomal protein of the small subunit
similar to uniprot|P53306 Saccharomyces cerevisiae YGR216C GPI1 Membrane protein involved in the synthesis of N-acetylglucosaminyl phosphatidylinositol
similar to uniprot|P50077 Saccharomyces cerevisiae YGR217W CCH1 Voltage-gated calcium channel involved in calcium influx in response to mating pheromones
similar to uniprot|Q02979 Saccharomyces cerevisiae YPL110C Hypothetical ORF
similar to uniprot|Q02981 Saccharomyces cerevisiae YPL109C Hypothetical ORF
highly similar to uniprot|P38116 Saccharomyces cerevisiae YBR164C ARL1 Soluble GTPase with a role in regulation of membrane traffic; regulates potassium influx; G protein of the Ras superfamily, similar to ADP-ribosylation factor
similar to gnl|GLV|CAGL0I10813g Candida glabrata CAGL0I10813g and some similarities with uniprot|P38290 Saccharomyces cerevisiae YBR165W UBS1 Ubiquitin-conjugating enzyme suppressor that functions as a general positive regulator of Cdc34p activity nuclear protein that may represent a link between nucleocytoplasmic transport and ubiquitin ligase activity
similar to uniprot|P20049 Saccharomyces cerevisiae YBR166C TYR1 Step of tyrosine biosynthesis pathway Prephenate dehydrogenase (NADP)
similar to uniprot|P32459 Saccharomyces cerevisiae YIR032C DAL3 Ureidoglycolate hydrolase converts ureidoglycolate to glyoxylate and urea in the third step of allantoin degradation expression sensitive to nitrogen catabolite repression
similar to uniprot|Q02872 Saccharomyces cerevisiae YPL108W Hypothetical ORF
similar to uniprot|P38291 Saccharomyces cerevisiae YBR167C POP7 Subunit of both RNase MRP which cleaves pre-rRNA and nuclear RNase P which cleaves tRNA precursors to generate mature 5' ends
similar to uniprot|P38292 Saccharomyces cerevisiae YBR168W PEX32 Peroxisomal integral membrane protein involved in negative regulation of peroxisome size partially functionally redundant with Pex31p genetic interactions suggest action at a step downstream of steps mediated by Pex28p and Pex29p
similar to uniprot|Q02873 Saccharomyces cerevisiae YPL107W Hypothetical ORF
highly similar to uniprot|P32589 Saccharomyces cerevisiae YPL106C SSE1 HSP70 family member highly homologous to Ssa1p and Sse2p
similar to uniprot|P36062 Saccharomyces cerevisiae YKL146W AVT3 Vacuolar transporter exports large neutral amino acids from the vacuole member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters
highly similar to uniprot|P33299 Saccharomyces cerevisiae YKL145W RPT1 One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates required for optimal CDC20 transcription interacts with Rpn12p and the E3 ubiquitin-protein ligase Ubr1p
highly similar to uniprot|P35718 Saccharomyces cerevisiae YKL144C RPC25 RNA polymerase III subunit C25
similar to uniprot|P34078 Saccharomyces cerevisiae YKL143W LTV1 Protein required for growth at low temperature
similar to uniprot|P35719 Saccharomyces cerevisiae YKL142W
highly similar to uniprot|P47077 Saccharomyces cerevisiae YJL010C Protein required for cell viability
highly similar to uniprot|P47079 Saccharomyces cerevisiae YJL008C CCT8 Subunit of the cytosolic chaperonin Cct ring complex related to Tcp1p required for the assembly of actin and tubulins in vivo
similar to uniprot|P47061 Saccharomyces cerevisiae YJL029C VPS53 Required for Vacuolar Protein Sorting Vps53p is a hydrophilic protein that is peripherally associated with the late Golgi and forms a stable complex with Vps52p and Vps54p.
highly similar to uniprot|P40958 Saccharomyces cerevisiae YJL030W MAD2 Component of the spindle-assembly checkpoint complex which delays the onset of anaphase in cells with defects in mitotic spindle assembly forms a complex with Mad1p
highly similar to uniprot|Q00618 Saccharomyces cerevisiae YJL031C BET4 Alpha subunit of Type II geranylgeranyltransferase required for vesicular transport between the endoplasmic reticulum and the Golgi provides a membrane attachment moiety to Rab-like proteins Ypt1p and Sec4p
similar to uniprot|P46962 Saccharomyces cerevisiae YJL006C
similar to uniprot|P20448 Saccharomyces cerevisiae YJL033W HCA4 Putative nucleolar DEAD box RNA helicase high-copy number suppression of a U14 snoRNA processing mutant suggests an involvement in 18S rRNA synthesis
similar to uniprot|Q07930 Saccharomyces cerevisiae YLR016C Hypothetical ORF
highly similar to uniprot|P16474 Saccharomyces cerevisiae YJL034W KAR2 ATPase involved in protein import into the ER also acts as a chaperone to mediate protein folding in the ER and may play a role in ER export of soluble proteins regulates the unfolded protein response via interaction with Ire1p
similar to uniprot|P47058 Saccharomyces cerevisiae YJL035C TAD2 tRNA-specific adenosine-34 deaminase subunit Tad2p
highly similar to uniprot|P47057 Saccharomyces cerevisiae YJL036W SNX4 Sorting NeXin
similar to YLR015W, uniprot|P43132 Saccharomyces cerevisiae YLR015W (BRE2)
similar to uniprot|P07272 Saccharomyces cerevisiae YLR014C PPR1 Zinc finger transcription factor containing a Zn(2)-Cys(6) binuclear cluster domain positively regulates transcription of genes involved in uracil biosynthesis activity may be modulated by interaction with Tup1p
highly similar to uniprot|Q07748 Saccharomyces cerevisiae YDL244W THI13 Protein involved in synthesis of the thiamine precursor hydroxymethylpyrimidine (HMP) member of a subtelomeric gene family including THI5 THI11 THI12 and THI13
similar to uniprot|Q07915 Saccharomyces cerevisiae YLR009W RLP24 Ribosomal Like Protein 24
similar to uniprot|Q07914 Saccharomyces cerevisiae YLR008C PAM18 Constituent of the mitochondrial import motor associated with the presequence translocase along with Ssc1p Tim44p Mge1p and Pam16p stimulates the ATPase activity of Ssc1p to drive mitochondrial import contains a J domain
similar to uniprot|Q07913 Saccharomyces cerevisiae YLR007W NSE1 Essential nuclear protein required for DNA repair forms a complex with Smc5p and Rhc18p
some similarities with uniprot|Q22X91 Tetrahymena thermophila SB210 TTHERM_00561660 Viral A-type inclusion protein repeat containing protein
similar to uniprot|Q07084 Saccharomyces cerevisiae YLR006C SSK1 Cytoplasmic response regulator part of a two-component signal transducer that mediates osmosensing via a phosphorelay mechanism dephosphorylated form is degraded by the ubiquitin-proteasome system potential Cdc28p substrate
highly similar to uniprot|Q04673 YLR005W Saccharomyces cerevisiae SSL1 Component of RNA polymerase transcription factor TFIIH
similar to uniprot|Q07904 Saccharomyces cerevisiae YLR004C Hypothetical ORF
similar to Q07897 YLR003C uniprot|Q07897 Saccharomyces cerevisiaeCMS1 Hypothetical ORF
similar to uniprot|P27351 Saccharomyces cerevisiae YJR005W APL1 beta-adaptin large subunit of the clathrin-associated protein complex
some similarities with uniprot|P20840 Saccharomyces cerevisiae YJR004C SAG1 Alpha-agglutinin of alpha-cells binds to Aga1p during agglutination N-terminal half is homologous to the immunoglobulin superfamily and contains binding site for a-agglutinin C-terminal half is highly glycosylated and contains GPI anchor
weakly similar to uniprot|O00026 Saccharomyces cerevisiae YOR066W Protein of unknown function potential Cdc28p substrate
highly similar to uniprot|P40351 Saccharomyces cerevisiae YOR067C ALG8 adds glucose to the dolichol-linked oligosaccharide precursor prior to transfer to protein glycosyl transferase
similar to uniprot|Q92331 Saccharomyces cerevisiae YOR069W VPS5 Component of the retromer coat that retrieves proteins from late endosomes sorting nexin I homolog
similar to uniprot|P36159 Saccharomyces cerevisiae YKR079C TRZ1 Protein required for cell viability
similar to uniprot|Q08484 Saccharomyces cerevisiae YOR070C GYP1 Cis-golgi GTPase-activating protein (GAP) for the Rab family members Ypt1p (in vivo) and for Ypt1p Sec4p Ypt7p and Ypt51p (in vitro) involved in vesicle docking and fusion
highly similar to uniprot|Q02046 Saccharomyces cerevisiae YKR080W MTD1 NAD-dependent 5 10-methylenetetrahydrafolate dehydrogenase plays a catalytic role in oxidation of cytoplasmic one-carbon units expression is regulated by Bas1p and Bas2p repressed by adenine and may be induced by inositol and choline
highly similar to uniprot|P36160 Saccharomyces cerevisiae YKR081C RPF2
similar to uniprot|P36161 Saccharomyces cerevisiae YKR082W NUP133 Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) localizes to both sides of the NPC required to establish a normal nucleocytoplasmic concentration gradient of the GTPase Gsp1p
similar to uniprot|P36162 Saccharomyces cerevisiae YKR083C DAD2 Essential protein component of the DASH complex involved in spindle integrity and kinetochore function interacts with Duo1p and Dam1p localizes to intranuclear spindles and kinetochore
similar to uniprot|Q08490 Saccharomyces cerevisiae YOR073W SGO1 Component of the spindle checkpoint involved in sensing lack of tension on mitotic chromosomes protects centromeric Rec8p at meiosis I required for accurate chromosomal segregation at meiosis II and for mitotic chromosome stability
highly similar to uniprot|P06785 Saccharomyces cerevisiae YOR074C CDC21 Thymidylate synthase required for de novo biosynthesis of pyrimidine deoxyribonucleotides expression is induced at G1/S
similar to uniprot|P41834 Saccharomyces cerevisiae YOR075W UFE1 t-SNARE that resides on the endoplasmic reticulum and mediates retrograde traffic from the Golgi complex potential Cdc28p substrate endoplasmic reticulum t-SNARE coprecipitates with Sec20p Tip1p. and Sec22p
similar to uniprot|P32769 Saccharomyces cerevisiae YKR084C HBS1 GTP binding protein
mitochondrial 54S ribosomal protein YmL20
similar to uniprot|P22354 Saccharomyces cerevisiae YKR085C MRPL20 Mitochondrial ribosomal protein of the large subunit
similar to uniprot|P15938 Saccharomyces cerevisiae YKR086W PRP16 RNA helicase in the DEAH-box family involved in the second catalytic step of splicing exhibits ATP-dependent RNA unwinding activity
similar to uniprot|P36163 Saccharomyces cerevisiae YKR087C OMA1 Metalloendopeptidase of the mitochondrial inner membrane involved in turnover of membrane-embedded proteins member of a family of predicted membrane-bound metallopeptidases in prokaryotes and higher eukaryotes
similar to uniprot|Q759P8 Ashbya gossypii ADR225W ADR225Wp and weakly similar to YOR077W uniprot|P40962 Saccharomyces cerevisiae
similar to uniprot|P36164 Saccharomyces cerevisiae YKR088C TVP38 Integral membrane protein localized to vesicles along with the v-SNARE Tlg2p green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
some similarities with uniprot|P38276 Saccharomyces cerevisiae YBR137W Hypothetical ORF
similar to uniprot|P53210 Saccharomyces cerevisiae YGR017W Hypothetical ORF
highly similar to uniprot|P17649 Saccharomyces cerevisiae YGR019W UGA1 Gamma-aminobutyrate (GABA) transaminase (4-aminobutyrate aminotransferase) involved in the 4-aminobutyrate and glutamate degradation pathways required for normal oxidative stress tolerance and nitrogen utilization
some similarities with uniprot|Q12114 Saccharomyces cerevisiae YLR330W CHS5 Protein of unknown function involved in chitin biosynthesis by regulating Chs3p localization also involved in cell fusion during mating
highly similar to uniprot|P39111 Saccharomyces cerevisiae YGR020C VMA7 Vacuolar H ATPase subunit F of the catalytic (V1) sector
similar to uniprot|P53212 Saccharomyces cerevisiae YGR021W Hypothetical ORF
some similarities with uniprot|P36027 Saccharomyces cerevisiae YLR332W MID2 Protein required for mating and to YGR023W uniprot|P53214 Saccharomyces cerevisiae YGR023W MTL1 Protein with both structural and functional similarity to Mid2p, which is a plasma membrane sensor required for cell integrity signaling during pheromone- induced morphogenesis; suppresses rgd1 null mutations
highly similar to uniprot|P53215 Saccharomyces cerevisiae YGR024C THG1 tRNAHis guanylyltransferase adds a guanosine residue to the 5' end of tRNAHis after transcription and RNase P cleavage essential enzyme conserved among eukaryotes
similar to uniprot|P53217 Saccharomyces cerevisiae YGR026W Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
C/D snoRNA polycistronic Cluster 2 SNR61
C/D snoRNA polycistronic Cluster 2 SNR55
C/D snoRNA polycistronic Cluster 2 SNR57
some similarities with uniprot|P07282 Saccharomyces cerevisiae YLR333C
weakly similar to uniprot|P32499 Saccharomyces cerevisiae YLR335W NUP2 Protein involved in nucleocytoplasmic transport binds to either the nucleoplasmic or cytoplasmic faces of the nuclear pore complex depending on Ran-GTP levels also has a role in chromatin organization
some similarities with uniprot|Q06132 Saccharomyces cerevisiae YLR336C SGD1 Suppressor of Glycerol Defect may be involved in high osmolarity signaling pathway
highly similar to uniprot|P28737 Saccharomyces cerevisiae YGR028W MSP1 Mitochondrial protein involved in sorting of proteins in the mitochondria putative membrane-spanning ATPase
highly similar to uniprot|P27882 Saccharomyces cerevisiae YGR029W
weakly similar to uniprot|Q06133 Saccharomyces cerevisiae YLR337C VRP1 Involved in cytoskeletal organization and cellular growth Proline-rich protein verprolin
similar to uniprot|P53218 Saccharomyces cerevisiae YGR030C POP6 Subunit of both RNase MRP which cleaves pre-rRNA and nuclear RNase P which cleaves tRNA precursors to generate mature 5' ends
highly similar to uniprot|P05317 Saccharomyces cerevisiae YLR340W RPP0 Conserved ribosomal protein P0 similar to rat P0, human P0, and E. coli L10e; shown to be phosphorylated on serine 302
some similarities with uniprot|Q06134 Saccharomyces cerevisiae YLR341W SPO77 Meiosis-specific protein of unknown function required for spore wall formation during sporulation dispensable for both nuclear divisions during meiosis
similar to uniprot|P53219 Saccharomyces cerevisiae YGR031W Hypothetical ORF
highly similar to uniprot|P38631 Saccharomyces cerevisiae YLR342W FKS1 Catalytic subunit of 1 3-beta-D-glucan synthase functionally redundant with alternate catalytic subunit Gsc2p binds to regulatory subunit Rho1p involved in cell wall synthesis and maintenance localizes to sites of cell wall remodeling or uniprot|P40989 Saccharomyces cerevisiae YGR032W GSC2
similar to uniprot|Q06135 Saccharomyces cerevisiae YLR343W GAS2 Putative 1,3-beta-glucanosyltransferase has similarity to Gas1p
similar to uniprot|P53220 Saccharomyces cerevisiae YGR033C FMP17 The authentic non-tagged protein was localized to the mitochondria
highly similar to uniprot|P05743 Saccharomyces cerevisiae YLR344W
similar to uniprot|Q06137 Saccharomyces cerevisiae YLR345W Hypothetical ORF
similar to uniprot|P53223 Saccharomyces cerevisiae YGR036C CAX4 Dolichyl pyrophosphate (Dol-P-P) phosphatase with a luminally oriented active site in the ER cleaves the anhydride linkage in Dol-P-P required for Dol-P-P- linked oligosaccharide intermediate synthesis and protein N-glycosylation
highly similar to uniprot|Q06142 Saccharomyces cerevisiae YLR347C KAP95 Karyopherin beta forms a dimeric complex with Srp1p (Kap60p) that mediates nuclear import of cargo proteins via a nuclear localization signal (NLS) interacts with nucleoporins to guide transport across the nuclear pore complex
highly similar to uniprot|P31787 Saccharomyces cerevisiae YGR037C ACB1 Acyl-CoA-binding protein transports newly synthesized acyl-CoA esters from fatty acid synthetase (Fas1p-Fas2p) to acyl-CoA-consuming processes
similar to uniprot|P53224 Saccharomyces cerevisiae YGR038W
highly similar to uniprot|P49954 Saccharomyces cerevisiae YLR351C
highly similar to uniprot|P14681 Saccharomyces cerevisiae YGR040W KSS1 Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways that control filamentous growth and pheromone response
similar to uniprot|Q06479 Saccharomyces cerevisiae YLR352W Hypothetical ORF
some similarities with uniprot|P41698 Saccharomyces cerevisiae YLR353W BUD8 Protein involved in bud-site selection diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern and bud at the proximal pole
weakly similar to uniprot|Q75CW0 Ashbya gossypii ACL194C ACL194Cp
highly similar to uniprot|P15019 Saccharomyces cerevisiae YLR354C TAL1 Transaldolase enzyme in the pentose phosphate pathway
some similarities with uniprot|P32338 Saccharomyces cerevisiae YGR044C RME1 mediates cell type control of sporulation negatively regulates IME1 and sporulation zinc finger protein negative regulator of meiosis directly repressed by a1-a2 regulator
weakly similar to uniprot|P34227 Saccharomyces cerevisiae YBL064C
similar to uniprot|P38129 Saccharomyces cerevisiae YBR198C TAF5 Subunit (90 kDa) of TFIID and SAGA complexes involved in RNA polymerase II transcription initiation and in chromatin modification
similar to uniprot|P46961 Saccharomyces cerevisiae YPL076W GPI2 Protein involved in the synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI) the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors homologous to the human PIG-C protein
some similarities with uniprot|Q02831 Saccharomyces cerevisiae YPL077C Hypothetical ORF
highly similar to uniprot|P12709 Saccharomyces cerevisiae YBR196C PGI1 Glycolytic enzyme phosphoglucose isomerase catalyzes the interconversion of glucose-6-phosphate and fructose-6-phosphate required for cell cycle progression and completion of the gluconeogenic events of sporulation
similar to uniprot|P13712 Saccharomyces cerevisiae YBR195C MSI1 Subunit of chromatin assembly factor I (CAF-I) regulates the RAS/cAMP pathway via sequestration of Npr1p kinase localizes to the nucleus and cytoplasm homologous to human retinoblastoma binding proteins RbAp48 and RbAp46
highly similar to uniprot|P05626 Saccharomyces cerevisiae YPL078C ATP4 Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase which is a large evolutionarily conserved enzyme complex required for ATP synthesis
some similarities with uniprot|P38305 Saccharomyces cerevisiae YBR194W SOY1 Synthetic with Old Yellow Enzyme
similar to uniprot|P38304 Saccharomyces cerevisiae YBR193C MED8 Member of RNA Polymerase II transcriptional regulation mediator Stoichiometric member of mediator complex
highly similar to uniprot|P38127 Saccharomyces cerevisiae YBR192W RIM2 Protein of the mitochondrial carrier (MCF) family that is required for respiration Probable carrier protein mitochondrial
highly similar to uniprot|Q02753 Saccharomyces cerevisiae YBR191W
highly similar to uniprot|O13516 Saccharomyces cerevisiae YPL081W RPS9A and to uniprot|P05755 Saccharomyces cerevisiae YBR189W RPS9B Proteins component of the small (40S) ribosomal subunit
highly similar to uniprot|Q12122 Saccharomyces cerevisiae YDL131W LYS21 and to uniprot|P48570 Saccharomyces cerevisiae YDL182W LYS20 homocitrate synthase
highly similar to uniprot|P32333 Saccharomyces cerevisiae YPL082C MOT1 Essential abundant protein involved in regulation of transcription removes Spt15p (TBP) from DNA via its C-terminal ATPase activity forms a complex with TBP that binds TATA DNA with high affinity but with altered specificity
similar to uniprot|P38301 Saccharomyces cerevisiae YBR187W Hypothetical ORF
similar to uniprot|P38126 Saccharomyces cerevisiae YBR186W PCH2 Nucleolar component of the pachytene checkpoint which prevents chromosome segregation when recombination and chromosome synapsis are defective also represses meiotic interhomolog recombination in the rDNA
similar to uniprot|Q02825 Saccharomyces cerevisiae YPL083C SEN54 Subunit of the tRNA splicing endonuclease which is composed of Sen2p Sen15p Sen34p and Sen54p
similar to uniprot|P48582 Saccharomyces cerevisiae YPL084W BRO1 Cytoplasmic class E vacuolar protein sorting (VPS) factor that coordinates deubiquitination in the multivesicular body (MVB) pathway by recruiting Doa4p to endosomes
similar to uniprot|P38300 Saccharomyces cerevisiae YBR185C MBA1 Protein involved in assembly of mitochondrial respiratory complexes may act as a receptor for proteins destined for export from the mitochondrial matrix to the inner membrane
some similarities with uniprot|P48415 Saccharomyces cerevisiae YPL085W SEC16 COPII vesicle coat protein required for ER transport vesicle budding and autophagosome formation Sec16p is bound to the periphery of ER membranes and may act to stabilize initial COPII complexes interacts with Sec23p Sec24p and Sec31p
highly similar to uniprot|Q02908 Saccharomyces cerevisiae YPL086C ELP3 Histone acetyltransferase subunit of the Elongator complex which is a component of the RNA polymerase II holoenzyme activity is directed specifically towards histones H3 and H4 disruption confers resistance to K. lactis zymotoxin
similar to uniprot|Q02896 Saccharomyces cerevisiae YPL087W YDC1 Yeast dihydro-ceramidase alkaline dihydroceramidase with minor reverse activity.
some similarities with uniprot|P38128 Saccharomyces cerevisiae YBR182C SMP1 Transcription factor of the MADS (Mcm1p Agamous Deficiens SRF) box family closely related to RLM1 Probable DNA-binding transcription factor Homolog to SRF/SL-2
similar to uniprot|P15992 Saccharomyces cerevisiae YBR072W HSP26 Small heat shock protein with chaperone activity that is regulated by a heat induced transition from an inactive oligomeric (24-mer) complex to an active dimer induced by heat upon entry into stationary phase and during sporulation
similar to uniprot|P05066 Saccharomyces cerevisiae YOR386W PHR1 DNA photolyase involved in photoreactivation repairs pyrimidine dimers in the presence of visible light induced by DNA damage regulated by transcriptional repressor Rph1p
similar to uniprot|Q2US70 Aspergillus oryzae AO090005000547 Predicted protein
similar to uniprot|P53183 Saccharomyces cerevisiae YGL039W and similar to uniprot|P53111 Saccharomyces cerevisiae YGL157W
similar to gnl|GLV|KLLA0D10153g Kluyveromyces lactis KLLA0D10153g and weakly similar to uniprot|P35995 Saccharomyces cerevisiae YKL222C Hypothetical ORF
similar to uniprot|P38124 Saccharomyces cerevisiae YBR008C FLR1 Plasma membrane multidrug transporter member of the major facilitator superfamily involved in efflux of fluconazole diazaborine benomyl methotrexate and other drugs
similar to uniprot|P40582 Saccharomyces cerevisiae YIR038C GTT1 ER associated glutathione S-transferase capable of homodimerization expression induced during the diauxic shift and throughout stationary phase functional overlap with Gtt2p Grx1p and Grx2p
some similarities with uniprot|P08640 Saccharomyces cerevisiae YIR019C MUC1 GPI-anchored cell surface glycoprotein required for diploid pseudohyphal formation and haploid invasive growth transcriptionally regulated by the MAPK pathway (via Ste12p and Tec1p) and the cAMP pathway (via Flo8p)
some similarities with uniprot|P38363 Saccharomyces cerevisiae YML132W COS3 Protein involved in salt resistance interacts with sodium:hydrogen antiporter Nha1p member of a family of conserved often subtelomerically- encoded proteins
some similarities with uniprot|P53344 Saccharomyces cerevisiae YGR295C COS6 Protein of unknown function member of a family of conserved often subtelomerically-encoded proteins
similar to uniprot|P53630 Saccharomyces cerevisiae YNR057C BIO4 Dethiobiotin synthetase catalyzes the third step in the biotin biosynthesis pathway BIO4 is in a cluster of 3 genes (BIO3 BIO4 and BIO5) that mediate biotin synthesis expression appears to be repressed at low iron levels
similar to uniprot|P50277 Saccharomyces cerevisiae YNR058W BIO3 7 8-diamino-pelargonic acid aminotransferase (DAPA) catalyzes the second step in the biotin biosynthesis pathway BIO3 is in a cluster of 3 genes (BIO3 BIO4 and BIO5) that mediate biotin synthesis