Halorubrum lacusprofundi ATCC 49239 chromosome 2, complete sequence.
Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales; Haloferacaceae; Halorubrum.
Extremophilic models for astrobiology: haloarchaeal survival strategies and pigments for remote sensing
An Antarctic Extreme Halophile and Its Polyextremophilic Enzyme: Effects of Perchlorate Salts
Key amino acid residues conferring enhanced enzyme activity at cold temperatures in an Antarctic polyextremophilic beta-galactosidase
Complete genome sequence of the Antarctic Halorubrum lacusprofundi type strain ACAM 34
Cloning, overexpression, purification, and characterization of a polyextremophilic beta-galactosidase from the Antarctic haloarchaeon Halorubrum lacusprofundi
Amino acid substitutions in cold-adapted proteins from Halorubrum lacusprofundi, an extremely halophilic microbe from antarctica
Submitted (14-JAN-2009) US DOE Joint Genome Institute, 2800 Mitchell Drive B310, Walnut Creek, CA 94598-1698, USA
REFSEQ INFORMATION: The reference sequence is identical to\nCP001366.1.\nURL -- http://www.jgi.doe.gov\nJGI Project ID: 4001421\nSource DNA available from Ricardo Cavicchioli\n(r.cavicchioli@unsw.edu.au)\nArchaea available from ATCC: ATCC 49239\nContacts: Ricardo Cavicchioli (r.cavicchioli@unsw.edu.au)\n Shiladitya DasSarma (sdassarma@som.umaryland.edu)\n David Bruce (microbe@cuba.jgi-psf.org)\nAnnotation done by JGI-ORNL and JGI-PGF\nFinishing done by JGI-LANL\nFinished microbial genomes have been curated to close all gaps with\ngreater than 98% coverage of at least two independent clones. Each\nbase pair has a minimum q (quality) value of 30 and the total error\nrate is less than one per 50000.\nThe JGI and collaborators endorse the principles for the\ndistribution and use of large scale sequencing data adopted by the\nlarger genome sequencing community and urge users of this data to\nfollow them. it is our intention to publish the work of this\nproject in a timely fashion and we welcome collaborative\ninteraction on the project and analysis.\n(http://www.genome.gov/page.cfm?pageID=10506376).\nThe annotation was added by the NCBI Prokaryotic Genome Annotation\nPipeline (PGAP). Information about PGAP can be found here:\nhttps://www.ncbi.nlm.nih.gov/genome/annotation_prok/\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: NCBI RefSeq\nAnnotation Date :: 07/30/2023 10:05:28\nAnnotation Pipeline :: NCBI Prokaryotic Genome\n Annotation Pipeline (PGAP)\nAnnotation Method :: Best-placed reference protein\n set; GeneMarkS-2+\nAnnotation Software revision :: 6.5\nFeatures Annotated :: Gene; CDS; rRNA; tRNA; ncRNA\nGenes (total) :: 3,669\nCDSs (total) :: 3,607\nGenes (coding) :: 3,516\nCDSs (with protein) :: 3,516\nGenes (RNA) :: 62\nrRNAs :: 3, 3, 3 (5S, 16S, 23S)\ncomplete rRNAs :: 3, 3, 3 (5S, 16S, 23S)\ntRNAs :: 51\nncRNAs :: 2\nPseudo Genes (total) :: 91\nCDSs (without protein) :: 91\nPseudo Genes (ambiguous residues) :: 0 of 91\nPseudo Genes (frameshifted) :: 31 of 91\nPseudo Genes (incomplete) :: 68 of 91\nPseudo Genes (internal stop) :: 15 of 91\nPseudo Genes (multiple problems) :: 18 of 91\nCRISPR Arrays :: 2\n##Genome-Annotation-Data-END##\nCOMPLETENESS: full length.
COORDINATES: protein motif:HMM:TIGR02928.1
Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_006884331.1
incomplete; partial in the middle of a contig; missing N-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_004043169.1
frameshifted; internal stop; incomplete; partial in the middle of a contig; missing N-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_076612342.1
GO:0004803 - transposase activity [Evidence IEA]
ISH3-like element ISHla1 family transposase
COORDINATES: ab initio prediction:GeneMarkS-2+
Derived by automated computational analysis using gene prediction method: GeneMarkS-2+.
COORDINATES: similar to AA sequence:RefSeq:WP_012659166.1
GO:0015074 - DNA integration [Evidence IEA]; GO:0006310 - DNA recombination [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_012659167.1
COORDINATES: similar to AA sequence:RefSeq:WP_009486644.1
COORDINATES: similar to AA sequence:RefSeq:WP_009486643.1
COORDINATES: similar to AA sequence:RefSeq:WP_009486642.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0140658 - ATP-dependent chromatin remodeler activity [Evidence IEA]
COORDINATES: protein motif:HMM:NF039358.1
COORDINATES: similar to AA sequence:RefSeq:WP_004047200.1
COORDINATES: similar to AA sequence:RefSeq:WP_012659172.1
COORDINATES: similar to AA sequence:RefSeq:WP_009486640.1
COORDINATES: similar to AA sequence:RefSeq:WP_009486639.1
COORDINATES: similar to AA sequence:RefSeq:WP_012659174.1
COORDINATES: similar to AA sequence:RefSeq:WP_009486638.1
COORDINATES: similar to AA sequence:RefSeq:WP_012659175.1
COORDINATES: similar to AA sequence:RefSeq:WP_008322218.1
COORDINATES: similar to AA sequence:RefSeq:WP_009486637.1
COORDINATES: similar to AA sequence:RefSeq:WP_008441309.1
COORDINATES: similar to AA sequence:RefSeq:WP_004213885.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0016887 - ATP hydrolysis activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004043378.1
frameshifted; internal stop; incomplete; partial in the middle of a contig; missing C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_012659178.1
COORDINATES: similar to AA sequence:RefSeq:WP_012659179.1
COORDINATES: protein motif:HMM:NF012464.2
GO:0003677 - DNA binding [Evidence IEA]; GO:0000150 - DNA strand exchange activity [Evidence IEA]
GO:0006310 - DNA recombination [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_012659181.1
COORDINATES: similar to AA sequence:RefSeq:WP_007273776.1
helix-turn-helix domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_012659184.1
COORDINATES: similar to AA sequence:RefSeq:WP_012659186.1
COORDINATES: similar to AA sequence:RefSeq:WP_012659187.1
COORDINATES: similar to AA sequence:RefSeq:WP_013875645.1
COORDINATES: protein motif:HMM:NF024573.2
COORDINATES: protein motif:HMM:NF025005.2
COORDINATES: similar to AA sequence:RefSeq:WP_009486614.1
COORDINATES: protein motif:HMM:NF014250.2
GO:0003676 - nucleic acid binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_015910948.1
ISH6-like element ISHla10 family transposase
COORDINATES: similar to AA sequence:RefSeq:WP_009486612.1
COORDINATES: similar to AA sequence:RefSeq:WP_009486610.1
DNA double-strand break repair nuclease NurA
COORDINATES: similar to AA sequence:RefSeq:WP_009486609.1
COORDINATES: protein motif:HMM:NF024258.2
GO:0003677 - DNA binding [Evidence IEA]; GO:0046872 - metal ion binding [Evidence IEA]; GO:0042578 - phosphoric ester hydrolase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_015233663.1
COORDINATES: similar to AA sequence:RefSeq:WP_009486605.1
COORDINATES: similar to AA sequence:RefSeq:WP_012659194.1
GO:0016799 - hydrolase activity, hydrolyzing N-glycosyl compounds [Evidence IEA]; GO:0046872 - metal ion binding [Evidence IEA]
ADP-ribosylglycohydrolase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_009486603.1
COORDINATES: similar to AA sequence:RefSeq:WP_009486602.1
COORDINATES: similar to AA sequence:RefSeq:WP_009486601.1
COORDINATES: protein motif:HMM:NF012798.2
COORDINATES: similar to AA sequence:RefSeq:WP_009488264.1
ISH3-like element ISHla11 family transposase
COORDINATES: similar to AA sequence:RefSeq:WP_009486659.1
COORDINATES: similar to AA sequence:RefSeq:WP_009486658.1
COORDINATES: similar to AA sequence:RefSeq:WP_009486657.1
COORDINATES: similar to AA sequence:RefSeq:WP_009486656.1
COORDINATES: similar to AA sequence:RefSeq:WP_012659198.1
COORDINATES: similar to AA sequence:RefSeq:WP_009486655.1
COORDINATES: similar to AA sequence:RefSeq:WP_009486654.1
COORDINATES: similar to AA sequence:RefSeq:WP_009486653.1
COORDINATES: similar to AA sequence:RefSeq:WP_009486650.1
GO:0004519 - endonuclease activity [Evidence IEA]
HNH endonuclease signature motif containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_009486649.1
ribonuclease H-like domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_009486648.1
COORDINATES: similar to AA sequence:RefSeq:WP_007274025.1
COORDINATES: similar to AA sequence:RefSeq:WP_006054136.1
COORDINATES: similar to AA sequence:RefSeq:WP_009486645.1
COORDINATES: protein motif:HMM:NF036452.2
COORDINATES: protein motif:HMM:TIGR02228.1
GO:0004252 - serine-type endopeptidase activity [Evidence IEA]
COORDINATES: protein motif:HMM:NF040138.1
COORDINATES: similar to AA sequence:RefSeq:WP_009378113.1
COORDINATES: similar to AA sequence:RefSeq:WP_004060649.1
COORDINATES: similar to AA sequence:RefSeq:WP_004060648.1
COORDINATES: similar to AA sequence:RefSeq:WP_008364345.1
frameshifted; incomplete; partial in the middle of a contig; missing N-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_010904194.1
GO:0003688 - DNA replication origin binding [Evidence IEA]
GO:0006260 - DNA replication [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008446344.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053340.1
COORDINATES: similar to AA sequence:RefSeq:WP_020221492.1
COORDINATES: similar to AA sequence:RefSeq:WP_009762257.1
COORDINATES: similar to AA sequence:RefSeq:WP_012659219.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053352.1
ArdC-like ssDNA-binding domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_006183341.1
COORDINATES: similar to AA sequence:RefSeq:WP_004517739.1
frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_012659224.1
COORDINATES: similar to AA sequence:RefSeq:WP_012659225.1
COORDINATES: similar to AA sequence:RefSeq:WP_006053683.1
COORDINATES: similar to AA sequence:RefSeq:WP_012659227.1
winged helix-turn-helix domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_004594486.1
GO:0016152 - mercury (II) reductase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_014050599.1
COORDINATES: protein motif:HMM:NF012401.2
COORDINATES: similar to AA sequence:RefSeq:WP_012659230.1
COORDINATES: similar to AA sequence:RefSeq:WP_012659231.1
GO:0008495 - protoheme IX farnesyltransferase activity [Evidence IEA]
GO:0048034 - heme O biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_012659232.1
COORDINATES: similar to AA sequence:RefSeq:WP_012659234.1
ISH3-like element ISHla8 family transposase
COORDINATES: similar to AA sequence:RefSeq:WP_004597785.1
bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase
COORDINATES: similar to AA sequence:RefSeq:WP_008440863.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]
GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007997751.1
COORDINATES: similar to AA sequence:RefSeq:WP_008440855.1
GO:0140359 - ABC-type transporter activity [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007997753.1
GO:0008643 - carbohydrate transport [Evidence IEA]; GO:0055085 - transmembrane transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008848339.1
GO:0140359 - ABC-type transporter activity [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA]; GO:0016887 - ATP hydrolysis activity [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007997758.1
GO:0008869 - galactonate dehydratase activity [Evidence IEA]
GO:0009063 - amino acid catabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004597790.1
GO:0016491 - oxidoreductase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_012659244.1
COORDINATES: similar to AA sequence:RefSeq:WP_008848343.1
COORDINATES: similar to AA sequence:RefSeq:WP_008440848.1
GO:0008671 - 2-dehydro-3-deoxygalactonokinase activity [Evidence IEA]; GO:0008673 - 2-dehydro-3-deoxygluconokinase activity [Evidence IEA]
bifunctional 2-dehydro-3-deoxygluconokinase/2-dehydro-3- deoxygalactonokinase
COORDINATES: similar to AA sequence:RefSeq:WP_012659247.1
IS200/IS605-like element ISHla17 family transposase
COORDINATES: similar to AA sequence:RefSeq:WP_006054393.1
RNA-guided endonuclease TnpB family protein
COORDINATES: similar to AA sequence:RefSeq:WP_008365099.1
GO:0016779 - nucleotidyltransferase activity [Evidence IEA]
GO:0009058 - biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_012659250.1
IS5-like element ISHla7 family transposase
COORDINATES: similar to AA sequence:RefSeq:WP_006182239.1
COORDINATES: similar to AA sequence:RefSeq:WP_006183369.1
incomplete; partial in the middle of a contig; missing N-terminus and C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
transcription initiation factor IIB family protein
COORDINATES: similar to AA sequence:RefSeq:WP_008364775.1
COORDINATES: similar to AA sequence:RefSeq:WP_012660138.1
COORDINATES: similar to AA sequence:RefSeq:WP_009488186.1
COORDINATES: similar to AA sequence:RefSeq:WP_004048599.1
COORDINATES: similar to AA sequence:RefSeq:WP_004971387.1
SWIM zinc finger domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_004043411.1
COORDINATES: similar to AA sequence:RefSeq:WP_014865851.1
COORDINATES: similar to AA sequence:RefSeq:WP_006183366.1
COORDINATES: similar to AA sequence:RefSeq:WP_004048595.1
COORDINATES: similar to AA sequence:RefSeq:WP_004043407.1
COORDINATES: protein motif:HMM:NF028237.2
COORDINATES: similar to AA sequence:RefSeq:WP_009367590.1
COORDINATES: similar to AA sequence:RefSeq:WP_004971481.1
COORDINATES: similar to AA sequence:RefSeq:WP_008444947.1
COORDINATES: similar to AA sequence:RefSeq:WP_004594499.1
COORDINATES: similar to AA sequence:RefSeq:WP_006183361.1
COORDINATES: similar to AA sequence:RefSeq:WP_004048585.1
COORDINATES: similar to AA sequence:RefSeq:WP_008458040.1
COORDINATES: similar to AA sequence:RefSeq:WP_008580586.1
COORDINATES: similar to AA sequence:RefSeq:WP_015911446.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0004519 - endonuclease activity [Evidence IEA]
GO:0009307 - DNA restriction-modification system [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008444956.1
COORDINATES: similar to AA sequence:RefSeq:WP_008524600.1
COORDINATES: similar to AA sequence:RefSeq:WP_015911449.1
GO:0043565 - sequence-specific DNA binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_015911559.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0004803 - transposase activity [Evidence IEA]
GO:0006313 - DNA transposition [Evidence IEA]
frameshifted; incomplete; partial in the middle of a contig; missing N-terminus and C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: nucleotide motif:Rfam:14.4:RF01959
Derived by automated computational analysis using gene prediction method: cmsearch.
Derived by automated computational analysis using gene prediction method: tRNAscan-SE.
COORDINATES: nucleotide motif:Rfam:14.4:RF02540
COORDINATES: nucleotide motif:Rfam:14.4:RF00001
COORDINATES: similar to AA sequence:RefSeq:WP_008458786.1
COORDINATES: similar to AA sequence:RefSeq:WP_017343668.1
COORDINATES: similar to AA sequence:RefSeq:WP_008005072.1
COORDINATES: similar to AA sequence:RefSeq:WP_007273858.1
COORDINATES: protein motif:HMM:NF025054.2
GO:0008080 - N-acetyltransferase activity [Evidence IEA]
COORDINATES: protein motif:HMM:NF013584.2
GO:0016810 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Evidence IEA]
COORDINATES: protein motif:HMM:NF012235.2
COORDINATES: protein motif:HMM:NF014684.2
GO:0015803 - branched-chain amino acid transport [Evidence IEA]
branched-chain amino acid ABC transporter permease
COORDINATES: protein motif:HMM:TIGR01910.1
GO:0016787 - hydrolase activity [Evidence IEA]
COORDINATES: protein motif:HMM:NF013046.2
COORDINATES: similar to AA sequence:RefSeq:WP_004595530.1
COORDINATES: similar to AA sequence:RefSeq:WP_008847771.1
ribbon-helix-helix domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_008847774.1
COORDINATES: similar to AA sequence:RefSeq:WP_014050724.1
COORDINATES: similar to AA sequence:RefSeq:WP_007344026.1
GO:0005515 - protein binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004046994.1
COORDINATES: similar to AA sequence:RefSeq:WP_006166239.1
COORDINATES: similar to AA sequence:RefSeq:WP_012660096.1
IS200/IS605-like element ISHla21 family transposase
COORDINATES: similar to AA sequence:RefSeq:WP_007997775.1
GO:0070007 - glutamic-type endopeptidase activity [Evidence IEA]
GO:0071586 - CAAX-box protein processing [Evidence IEA]
CPBP family glutamic-type intramembrane protease
COORDINATES: similar to AA sequence:RefSeq:WP_006112253.1
COORDINATES: similar to AA sequence:RefSeq:WP_004595455.1
COORDINATES: similar to AA sequence:RefSeq:WP_008846876.1
COORDINATES: similar to AA sequence:RefSeq:WP_004046990.1
COORDINATES: similar to AA sequence:RefSeq:WP_017343339.1
COORDINATES: similar to AA sequence:RefSeq:WP_008580651.1
phage integrase SAM-like domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_007992728.1
COORDINATES: similar to AA sequence:RefSeq:WP_017343634.1
GO:0004748 - ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [Evidence IEA]
ribonucleoside-diphosphate reductase subunit alpha
COORDINATES: similar to AA sequence:RefSeq:WP_012807515.1
GO:0005971 - ribonucleoside-diphosphate reductase complex [Evidence IEA]
GO:0046872 - metal ion binding [Evidence IEA]; GO:0004748 - ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [Evidence IEA]
GO:0009263 - deoxyribonucleotide biosynthetic process [Evidence IEA]; GO:0006260 - DNA replication [Evidence IEA]
ribonucleotide-diphosphate reductase subunit beta
COORDINATES: similar to AA sequence:RefSeq:WP_008580558.1
GO:0140110 - transcription regulator activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_012945391.1
COORDINATES: similar to AA sequence:RefSeq:WP_007998592.1
COORDINATES: similar to AA sequence:RefSeq:WP_007998602.1
COORDINATES: similar to AA sequence:RefSeq:WP_006628464.1
COORDINATES: similar to AA sequence:RefSeq:WP_006183539.1
orc1/cdc6 family replication initiation protein
COORDINATES: protein motif:HMM:NF020645.2
COORDINATES: protein motif:HMM:NF040570.1
COORDINATES: similar to AA sequence:RefSeq:WP_004977664.1
COORDINATES: similar to AA sequence:RefSeq:WP_008444896.1
COORDINATES: similar to AA sequence:RefSeq:WP_010904033.1
COORDINATES: similar to AA sequence:RefSeq:WP_008443992.1
COORDINATES: similar to AA sequence:RefSeq:WP_008443994.1
COORDINATES: similar to AA sequence:RefSeq:WP_006630784.1
COORDINATES: similar to AA sequence:RefSeq:WP_008847016.1
COORDINATES: similar to AA sequence:RefSeq:WP_008446225.1
COORDINATES: similar to AA sequence:RefSeq:WP_008446216.1
COORDINATES: similar to AA sequence:RefSeq:WP_015911445.1
COORDINATES: similar to AA sequence:RefSeq:WP_006111752.1
COORDINATES: protein motif:HMM:NF037417.2
COORDINATES: protein motif:HMM:TIGR04126.1
PGF-CTERM sorting domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_007998268.1
glutathione S-transferase C-terminal domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_004596545.1
GO:0003824 - catalytic activity [Evidence IEA]
GO:0009228 - thiamine biosynthetic process [Evidence IEA]
sulfide-dependent adenosine diphosphate thiazole synthase
COORDINATES: protein motif:HMM:NF016214.2
COORDINATES: protein motif:HMM:NF024808.2
COORDINATES: similar to AA sequence:RefSeq:WP_008327238.1
COORDINATES: similar to AA sequence:RefSeq:WP_008097104.1
GO:0050334 - thiaminase activity [Evidence IEA]
GO:0006772 - thiamine metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_014050606.1
GO:0008902 - hydroxymethylpyrimidine kinase activity [Evidence IEA]; GO:0008972 - phosphomethylpyrimidine kinase activity [Evidence IEA]
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
COORDINATES: similar to AA sequence:RefSeq:WP_014050605.1
GO:0046872 - metal ion binding [Evidence IEA]
heavy-metal-associated domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_015911518.1
COORDINATES: similar to AA sequence:RefSeq:WP_014050603.1
COORDINATES: similar to AA sequence:RefSeq:WP_014050602.1
GO:0004148 - dihydrolipoyl dehydrogenase activity [Evidence IEA]
GO:0045454 - cell redox homeostasis [Evidence IEA]; GO:0051068 - dihydrolipoamide metabolic process [Evidence IEA]; GO:0006096 - glycolytic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008385356.1
COORDINATES: similar to AA sequence:RefSeq:WP_014050600.1
COORDINATES: similar to AA sequence:RefSeq:WP_015299360.1
COORDINATES: similar to AA sequence:RefSeq:WP_008387661.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053400.1
COORDINATES: similar to AA sequence:RefSeq:WP_006183441.1
COORDINATES: similar to AA sequence:RefSeq:WP_009488251.1
COORDINATES: similar to AA sequence:RefSeq:WP_009488252.1
COORDINATES: similar to AA sequence:RefSeq:WP_009488254.1
COORDINATES: similar to AA sequence:RefSeq:WP_009488255.1
COORDINATES: similar to AA sequence:RefSeq:WP_004060473.1
COORDINATES: similar to AA sequence:RefSeq:WP_009488260.1
PQQ-binding-like beta-propeller repeat protein
COORDINATES: similar to AA sequence:RefSeq:WP_004060462.1
COORDINATES: similar to AA sequence:RefSeq:WP_009488261.1
IS5-like element ISHla2 family transposase
COORDINATES: similar to AA sequence:RefSeq:WP_009488262.1
COORDINATES: similar to AA sequence:RefSeq:WP_009488263.1
COORDINATES: protein motif:HMM:NF016724.2
GO:0005524 - ATP binding [Evidence IEA]; GO:0003677 - DNA binding [Evidence IEA]; GO:0016787 - hydrolase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_009762328.1
COORDINATES: similar to AA sequence:RefSeq:WP_008445014.1
COORDINATES: similar to AA sequence:RefSeq:WP_009762326.1
COORDINATES: similar to AA sequence:RefSeq:WP_009762325.1
COORDINATES: protein motif:HMM:NF021378.2
COORDINATES: protein motif:HMM:NF012355.2
GO:0005507 - copper ion binding [Evidence IEA]; GO:0009055 - electron transfer activity [Evidence IEA]
plastocyanin/azurin family copper-binding protein
COORDINATES: protein motif:HMM:NF012314.2
COORDINATES: similar to AA sequence:RefSeq:WP_009762322.1
COORDINATES: similar to AA sequence:RefSeq:WP_009762321.1
COORDINATES: similar to AA sequence:RefSeq:WP_007997629.1
COORDINATES: similar to AA sequence:RefSeq:WP_009762319.1
COORDINATES: similar to AA sequence:RefSeq:WP_009762318.1
GO:0009166 - nucleotide catabolic process [Evidence IEA]
5'-nucleotidase C-terminal domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_009762317.1
sulfite exporter TauE/SafE family protein
COORDINATES: similar to AA sequence:RefSeq:WP_009762316.1
COORDINATES: similar to AA sequence:RefSeq:WP_009762315.1
COORDINATES: similar to AA sequence:RefSeq:WP_009762314.1
COORDINATES: similar to AA sequence:RefSeq:WP_009762313.1
GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; GO:0003994 - aconitate hydratase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008421826.1
DUF2080 family transposase-associated protein
COORDINATES: similar to AA sequence:RefSeq:WP_004044073.1
IS5-like element ISHla6 family transposase
COORDINATES: protein motif:HMM:NF024595.2
COORDINATES: protein motif:HMM:NF019850.2
COORDINATES: protein motif:HMM:NF025467.2
poly-gamma-glutamate biosynthesis protein PgsC/CapC
COORDINATES: similar to AA sequence:RefSeq:WP_006053378.1
COORDINATES: similar to AA sequence:RefSeq:WP_007692798.1
zinc-dependent alcohol dehydrogenase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_007345627.1
COORDINATES: similar to AA sequence:RefSeq:WP_009762312.1
COORDINATES: similar to AA sequence:RefSeq:WP_004048645.1
GO:0042625 - ATPase-coupled ion transmembrane transporter activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008002191.1
COORDINATES: similar to AA sequence:RefSeq:WP_009762307.1
COORDINATES: similar to AA sequence:RefSeq:WP_009762306.1
6-pyruvoyl tetrahydropterin synthase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_004595531.1
GO:0008616 - queuosine biosynthetic process [Evidence IEA]
COORDINATES: protein motif:HMM:NF013224.2
Lrp/AsnC family transcriptional regulator
COORDINATES: similar to AA sequence:RefSeq:WP_009762302.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053537.1
COORDINATES: similar to AA sequence:RefSeq:WP_009762300.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053535.1
IS5-like element ISHla3 family transposase
COORDINATES: similar to AA sequence:RefSeq:WP_014053534.1
COORDINATES: similar to AA sequence:RefSeq:WP_006057031.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053532.1
COORDINATES: similar to AA sequence:RefSeq:WP_010890512.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053530.1
COORDINATES: similar to AA sequence:RefSeq:WP_009762281.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053528.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053527.1
COORDINATES: similar to AA sequence:RefSeq:WP_004516371.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053525.1
COORDINATES: similar to AA sequence:RefSeq:WP_015911548.1
COORDINATES: similar to AA sequence:RefSeq:WP_006186975.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053522.1
COORDINATES: similar to AA sequence:RefSeq:WP_006630746.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053521.1
IS5-like element ISHla4 family transposase
COORDINATES: similar to AA sequence:RefSeq:WP_014053375.1
COORDINATES: similar to AA sequence:RefSeq:WP_011222276.1
COORDINATES: protein motif:HMM:NF039368.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053380.1
COORDINATES: similar to AA sequence:RefSeq:WP_009762298.1
COORDINATES: similar to AA sequence:RefSeq:WP_009762297.1
COORDINATES: similar to AA sequence:RefSeq:WP_009762296.1
COORDINATES: similar to AA sequence:RefSeq:WP_008313916.1
COORDINATES: similar to AA sequence:RefSeq:WP_014557034.1
COORDINATES: similar to AA sequence:RefSeq:WP_014557033.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053516.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053518.1
COORDINATES: similar to AA sequence:RefSeq:WP_004594457.1
helix-turn-helix transcriptional regulator
COORDINATES: similar to AA sequence:RefSeq:WP_014053341.1
COORDINATES: similar to AA sequence:RefSeq:WP_011324411.1
COORDINATES: similar to AA sequence:RefSeq:WP_011572781.1
nucleotidyltransferase domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_008846865.1
type IV toxin-antitoxin system AbiEi family antitoxin
COORDINATES: similar to AA sequence:RefSeq:WP_009762211.1
COORDINATES: similar to AA sequence:RefSeq:WP_004595552.1
helix-turn-helix domain containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_006183447.1
COORDINATES: similar to AA sequence:RefSeq:WP_009488099.1
COORDINATES: similar to AA sequence:RefSeq:WP_009488098.1
COORDINATES: similar to AA sequence:RefSeq:WP_009488097.1
COORDINATES: similar to AA sequence:RefSeq:WP_009488096.1
COORDINATES: similar to AA sequence:RefSeq:WP_009488095.1
COORDINATES: similar to AA sequence:RefSeq:WP_009488094.1
COORDINATES: similar to AA sequence:RefSeq:WP_014050638.1
COORDINATES: similar to AA sequence:RefSeq:WP_009488093.1
COORDINATES: similar to AA sequence:RefSeq:WP_009488219.1
GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_009488221.1
COORDINATES: similar to AA sequence:RefSeq:WP_009488223.1
COORDINATES: similar to AA sequence:RefSeq:WP_009488224.1
COORDINATES: similar to AA sequence:RefSeq:WP_009488225.1
COORDINATES: similar to AA sequence:RefSeq:WP_004595756.1
COORDINATES: similar to AA sequence:RefSeq:WP_009488231.1
COORDINATES: similar to AA sequence:RefSeq:WP_009488232.1
COORDINATES: similar to AA sequence:RefSeq:WP_009488233.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053114.1
COORDINATES: similar to AA sequence:RefSeq:WP_017342075.1
COORDINATES: similar to AA sequence:RefSeq:WP_007143097.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053110.1
COORDINATES: similar to AA sequence:RefSeq:WP_008094346.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053108.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053107.1
COORDINATES: similar to AA sequence:RefSeq:WP_013881810.1
COORDINATES: similar to AA sequence:RefSeq:WP_007143091.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053230.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053229.1
type IV secretory system conjugative DNA transfer family protein
COORDINATES: similar to AA sequence:RefSeq:WP_014053228.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053227.1
COORDINATES: similar to AA sequence:RefSeq:WP_006183472.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053225.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053224.1
COORDINATES: similar to AA sequence:RefSeq:WP_006183475.1
COORDINATES: similar to AA sequence:RefSeq:WP_006183476.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053219.1
COORDINATES: similar to AA sequence:RefSeq:WP_015911581.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053217.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053216.1
COORDINATES: similar to AA sequence:RefSeq:WP_007190718.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053213.1
BREX-5 system adenine-specific DNA-methyltransferase PglX
COORDINATES: similar to AA sequence:RefSeq:WP_014053212.1
AbrB/MazE/SpoVT family DNA-binding domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_008524572.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053210.1
COORDINATES: similar to AA sequence:RefSeq:WP_008387701.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053208.1
COORDINATES: similar to AA sequence:RefSeq:WP_008446366.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053205.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0016887 - ATP hydrolysis activity [Evidence IEA]; GO:0003677 - DNA binding [Evidence IEA]; GO:0004386 - helicase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_014053204.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053203.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053202.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053201.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053200.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053199.1
COORDINATES: similar to AA sequence:RefSeq:WP_014053198.1
COORDINATES: protein motif:HMM:NF019325.2
COORDINATES: similar to AA sequence:RefSeq:WP_014053359.1
COORDINATES: similar to AA sequence:RefSeq:WP_008322086.1
COORDINATES: protein motif:HMM:NF015155.2
COORDINATES: protein motif:HMM:NF024640.2
prenyltransferase/squalene oxidase repeat-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_015911601.1
IS6-like element ISHla13 family transposase
COORDINATES: protein motif:HMM:NF024487.2
COORDINATES: protein motif:HMM:NF024117.2
COORDINATES: similar to AA sequence:RefSeq:WP_009486679.1
IS200/IS605-like element ISHla19 family transposase
COORDINATES: similar to AA sequence:RefSeq:WP_009486680.1
COORDINATES: similar to AA sequence:RefSeq:WP_011571411.1
COORDINATES: similar to AA sequence:RefSeq:WP_007258717.1
COORDINATES: similar to AA sequence:RefSeq:WP_006886087.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0003676 - nucleic acid binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_015911610.1
COORDINATES: similar to AA sequence:RefSeq:WP_007538790.1
COORDINATES: similar to AA sequence:RefSeq:WP_004978071.1
COORDINATES: protein motif:HMM:NF024935.2
internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_004060946.1
GO:0010181 - FMN binding [Evidence IEA]; GO:0016491 - oxidoreductase activity [Evidence IEA]
LLM class flavin-dependent oxidoreductase
COORDINATES: similar to AA sequence:RefSeq:WP_008847790.1
COORDINATES: similar to AA sequence:RefSeq:WP_005041088.1
COORDINATES: similar to AA sequence:RefSeq:WP_004061954.1
COORDINATES: similar to AA sequence:RefSeq:WP_013035178.1
COORDINATES: similar to AA sequence:RefSeq:WP_004514844.1
COORDINATES: protein motif:HMM:TIGR01439.1
COORDINATES: similar to AA sequence:RefSeq:WP_017342449.1
COORDINATES: similar to AA sequence:RefSeq:WP_007992454.1
COORDINATES: similar to AA sequence:RefSeq:WP_017344033.1
COORDINATES: similar to AA sequence:RefSeq:WP_009377036.1
COORDINATES: similar to AA sequence:RefSeq:WP_012289744.1
COORDINATES: similar to AA sequence:RefSeq:WP_014555704.1