Alcanivorax borkumensis SK2, complete sequence.
Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales; Alcanivoracaceae; Alcanivorax.
Genome sequence of the ubiquitous hydrocarbon-degrading marine bacterium Alcanivorax borkumensis
Submitted (11-JUL-2006) Martins dos Santos V.A.P., Division of Microbiology, German Research Center for Biotechnology, D-38124 Braunschweig, Germany Schneiker S.; Lehrstuhl fuer Genetik, Bielefeld University Universitaetsstrasse 25, 33615 Bielefeld, Germany
REFSEQ INFORMATION: The reference sequence is identical to\nAM286690.1.\nThe annotation was added by the NCBI Prokaryotic Genome Annotation\nPipeline (PGAP). Information about PGAP can be found here:\nhttps://www.ncbi.nlm.nih.gov/genome/annotation_prok/\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: NCBI RefSeq\nAnnotation Date :: 12/30/2022 00:44:16\nAnnotation Pipeline :: NCBI Prokaryotic Genome\n Annotation Pipeline (PGAP)\nAnnotation Method :: Best-placed reference protein\n set; GeneMarkS-2+\nAnnotation Software revision :: 6.4\nFeatures Annotated :: Gene; CDS; rRNA; tRNA; ncRNA\nGenes (total) :: 2,829\nCDSs (total) :: 2,774\nGenes (coding) :: 2,758\nCDSs (with protein) :: 2,758\nGenes (RNA) :: 55\nrRNAs :: 3, 3, 3 (5S, 16S, 23S)\ncomplete rRNAs :: 3, 3, 3 (5S, 16S, 23S)\ntRNAs :: 42\nncRNAs :: 4\nPseudo Genes (total) :: 16\nCDSs (without protein) :: 16\nPseudo Genes (ambiguous residues) :: 0 of 16\nPseudo Genes (frameshifted) :: 12 of 16\nPseudo Genes (incomplete) :: 10 of 16\nPseudo Genes (internal stop) :: 9 of 16\nPseudo Genes (multiple problems) :: 10 of 16\n##Genome-Annotation-Data-END##\nCOMPLETENESS: full length.
ATPase involved in DNA replication initiation
COORDINATES: similar to AA sequence:RefSeq:WP_011587299.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0003677 - DNA binding [Evidence IEA]; GO:0003688 - DNA replication origin binding [Evidence IEA]
GO:0006270 - DNA replication initiation [Evidence IEA]; GO:0006275 - regulation of DNA replication [Evidence IEA]
Derived by automated computational analysis using gene prediction method: Protein Homology.
chromosomal replication initiator protein DnaA
DNA polymerase sliding clamp subunit (PCNA homolog)
COORDINATES: similar to AA sequence:RefSeq:WP_008929681.1
GO:0009360 - DNA polymerase III complex [Evidence IEA]
GO:0003887 - DNA-directed DNA polymerase activity [Evidence IEA]
GO:0006260 - DNA replication [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007151545.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0003697 - single-stranded DNA binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007112183.1
GO:0009330 - DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex [Evidence IEA]
GO:0003918 - DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [Evidence IEA]
GO:0006265 - DNA topological change [Evidence IEA]
DNA topoisomerase (ATP-hydrolyzing) subunit B
play a role in the formation of nucleoide structure
COORDINATES: similar to AA sequence:RefSeq:WP_007150019.1
catalyzes the acylation of 1-acyl-sn-glycerol-3-phosphate to phosphatidic acid
COORDINATES: similar to AA sequence:RefSeq:WP_007148963.1
lysophospholipid acyltransferase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_007150797.1
GO:0016791 - phosphatase activity [Evidence IEA]
GO:0005975 - carbohydrate metabolic process [Evidence IEA]
D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase
atp + glycine + trna(gly) = amp + diphosphate + glycyl-trna(gly)
COORDINATES: similar to AA sequence:RefSeq:WP_008929675.1
GO:0009345 - glycine-tRNA ligase complex [Evidence IEA]
GO:0004820 - glycine-tRNA ligase activity [Evidence IEA]
GO:0006426 - glycyl-tRNA aminoacylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011587307.1
hydrolysis of the deoxyribose n-glycosidic bond to excise 3-methyladenine from the damaged dna polymer formed by alkylation lesions.
COORDINATES: similar to AA sequence:RefSeq:WP_014992386.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151617.1
COORDINATES: ab initio prediction:GeneMarkS-2+
Derived by automated computational analysis using gene prediction method: GeneMarkS-2+.
COORDINATES: similar to AA sequence:RefSeq:WP_007149702.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151316.1
GTPase/DUF3482 domain-containing protein
regulation of transcription, DNA-dependent
COORDINATES: similar to AA sequence:RefSeq:WP_008929931.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149132.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587314.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148400.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151297.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150073.1
2-methyl-3-oxopropanoate + coa + nad(+) = propanoyl-coa + co(2) + nadh
COORDINATES: similar to AA sequence:RefSeq:WP_010322022.1
CoA-acylating methylmalonate-semialdehyde dehydrogenase
Acyl-CoA + etf = 2,3-dehydroacyl-CoA + reduced etf.
COORDINATES: similar to AA sequence:RefSeq:WP_011587319.1
GO:0016627 - oxidoreductase activity, acting on the CH-CH group of donors [Evidence IEA]
3-hydroxy-2-methylpropanoate + nad(+) = 2-methyl-3-oxopropanoate + nadh.
COORDINATES: similar to AA sequence:RefSeq:WP_014996614.1
GO:0008442 - 3-hydroxyisobutyrate dehydrogenase activity [Evidence IEA]
GO:0006574 - valine catabolic process [Evidence IEA]
it catalyses the first step of phytanic acid alpha-oxidation
COORDINATES: similar to AA sequence:RefSeq:WP_007151254.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587322.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929906.1
COORDINATES: similar to AA sequence:RefSeq:WP_014992455.1
glutathione S-transferase family protein
converts holo-acp to apo-acp by hydrolytic cleavage of the phosphopantetheine prosthetic group from acp. its physiological function is not clear (by similarity). holo-[acyl-carrier protein] + h(2)o = 4'-phosphopantetheine + apo-[acyl-carrier protein].
COORDINATES: similar to AA sequence:RefSeq:WP_011587325.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151082.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929902.1
activates the flagella regulon by activating transcription of flhdc. may activate qseb by phosphorylation
COORDINATES: similar to AA sequence:RefSeq:WP_007149396.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148485.1
GO:0000160 - phosphorelay signal transduction system [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007151331.1
involved in disulfide bond formation. functions probably as a disulfide isomerase with a narrower substrate specificity than dsbc
COORDINATES: similar to AA sequence:RefSeq:WP_007149896.1
thiol:disulfide interchange protein DsbG
COORDINATES: similar to AA sequence:RefSeq:WP_008929900.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587333.1
GO:0016597 - amino acid binding [Evidence IEA]; GO:0004070 - aspartate carbamoyltransferase activity [Evidence IEA]
GO:0006207 - 'de novo' pyrimidine nucleobase biosynthetic process [Evidence IEA]; GO:0006520 - amino acid metabolic process [Evidence IEA]
aspartate carbamoyltransferase catalytic subunit
COORDINATES: similar to AA sequence:RefSeq:WP_011587334.1
GO:0009116 - nucleoside metabolic process [Evidence IEA]
bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR
electron transfer from hydrogen to oxygen
COORDINATES: similar to AA sequence:RefSeq:WP_007149081.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149052.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149894.1
DUF3298 and DUF4163 domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_011587338.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928969.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149782.1
hydrolysis of water- soluble or insoluble esters, including triglycerides
COORDINATES: similar to AA sequence:RefSeq:WP_007151635.1
directly reducing organic hyperoxides in its reduced dithiol form
COORDINATES: similar to AA sequence:RefSeq:WP_007150699.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928818.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149101.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928821.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587346.1
YajQ family cyclic di-GMP-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_008928824.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587348.1
removal of the ammonia group from a glutamate molecule and its subsequent transfer to a specific substrate, thus creating a new carbon-nitrogen group on the substrate
COORDINATES: similar to AA sequence:RefSeq:WP_007149567.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149986.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929670.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929667.1
TetR/AcrR family transcriptional regulator
COORDINATES: similar to AA sequence:RefSeq:WP_014992390.1
GO:0022857 - transmembrane transporter activity [Evidence IEA]
GO:0055085 - transmembrane transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008929665.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587355.1
COORDINATES: similar to AA sequence:RefSeq:WP_019018980.1
GO:0009055 - electron transfer activity [Evidence IEA]
cytochrome b/b6 domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_007150564.1
GO:0003747 - translation release factor activity [Evidence IEA]
GO:0006415 - translational termination [Evidence IEA]
alternative ribosome rescue aminoacyl-tRNA hydrolase ArfB
COORDINATES: similar to AA sequence:RefSeq:WP_008929660.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148682.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148896.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148577.1
OsmC domain/YcaO domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_008929654.1
GO:0046872 - metal ion binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_014995436.1
hydrolyses fumarylacetoacetate into fumarate and acetoacetate which then join the citric acid cycle
COORDINATES: similar to AA sequence:RefSeq:WP_007149556.1
GO:0003824 - catalytic activity [Evidence IEA]
fumarylacetoacetate hydrolase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_008930146.1
3-phosphoglycerate + NAD(+) = 3-phosphohydroxypyruvate + NADH.
COORDINATES: similar to AA sequence:RefSeq:WP_007149220.1
GO:0051287 - NAD binding [Evidence IEA]; GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008930148.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930149.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587369.1
penicillin-binding protein activator LpoB
COORDINATES: similar to AA sequence:RefSeq:WP_007149688.1
COORDINATES: protein motif:HMM:NF015863.2
PepSY-associated TM helix domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_008930153.1
transport system that facilitate potassium-efflux, possibly by potassium-proton antiport
COORDINATES: similar to AA sequence:RefSeq:WP_007149161.1
GO:0051139 - metal cation:proton antiporter activity [Evidence IEA]
GO:0006812 - monoatomic cation transport [Evidence IEA]; GO:1902600 - proton transmembrane transport [Evidence IEA]
monovalent cation:proton antiporter-2 (CPA2) family protein
COORDINATES: similar to AA sequence:RefSeq:WP_008930155.1
GO:0019867 - outer membrane [Evidence IEA]
GO:0015343 - siderophore-iron transmembrane transporter activity [Evidence IEA]
GO:0015891 - siderophore transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007151373.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151487.1
ggt plays a key role in the gamma-glutamyl cycle, a pathway for the synthesis and degradation of glutathione. (5-L-glutamyl)-peptide + an amino acid = peptide + 5-L-glutamyl-amino acid.
COORDINATES: similar to AA sequence:RefSeq:WP_007148360.1
GO:0006750 - glutathione biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150106.1
GO:0004595 - pantetheine-phosphate adenylyltransferase activity [Evidence IEA]
GO:0015937 - coenzyme A biosynthetic process [Evidence IEA]
pantetheine-phosphate adenylyltransferase
COORDINATES: protein motif:HMM:NF013677.2
COORDINATES: protein motif:HMM:NF024673.2
COORDINATES: protein motif:HMM:NF033516.0
GO:0004803 - transposase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148564.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151553.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149357.1
twin-arginine translocation signal domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_008930169.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148601.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149855.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151212.1
GO:0008168 - methyltransferase activity [Evidence IEA]
GO:0006364 - rRNA processing [Evidence IEA]
16S rRNA (uracil(1498)-N(3))-methyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_009099415.1
COORDINATES: similar to AA sequence:RefSeq:WP_008047755.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930174.1
COORDINATES: similar to AA sequence:RefSeq:WP_013661868.1
catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to s-lactoylglutathione ((r)-s-lactoylglutathione = glutathione + methylglyoxal)
COORDINATES: similar to AA sequence:RefSeq:WP_007149371.1
GO:0004462 - lactoylglutathione lyase activity [Evidence IEA]
GO:0005975 - carbohydrate metabolic process [Evidence IEA]; GO:0051596 - methylglyoxal catabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011587394.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148704.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930180.1
COORDINATES: similar to AA sequence:RefSeq:WP_014995942.1
Involved in biosynthesis of the lippopolysaccharide (LPS) component lipid A by acylation of the intermediate (KDO)2-lipid IVa to form (KDO)2-(lauroyl)-lipid IVa
COORDINATES: similar to AA sequence:RefSeq:WP_014992429.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587399.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150659.1
Chemotaxis response regulator containing a CheY
COORDINATES: similar to AA sequence:RefSeq:WP_007149138.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150949.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151257.1
protein-glutamate O-methyltransferase CheR
COG: Methyl-accepting chemotaxis protein
COORDINATES: similar to AA sequence:RefSeq:WP_011587404.1
GO:0007165 - signal transduction [Evidence IEA]
Chemotaxis signal transduction protein regulates twitching motility
COORDINATES: similar to AA sequence:RefSeq:WP_007150053.1
FOG response regulatory protein for twitching motility
COORDINATES: similar to AA sequence:RefSeq:WP_007151610.1
twitching motility response regulator PilH
response regulator involved in signal trasduction for pilus-biosynthesis
COORDINATES: similar to AA sequence:RefSeq:WP_011587407.1
twitching motility response regulator PilG
ATP + gamma-l-glutamyl-l-cysteine + glycine = ADP + phosphate + glutathione.
COORDINATES: similar to AA sequence:RefSeq:WP_007148391.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0004363 - glutathione synthase activity [Evidence IEA]; GO:0046872 - metal ion binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149240.1
GO:0015291 - secondary active transmembrane transporter activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011587410.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587411.1
GO:0003674 - molecular_function [Evidence IEA]
GO:0008150 - biological_process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008738829.1
COORDINATES: similar to AA sequence:RefSeq:WP_008738830.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929470.1
GO:0018738 - S-formylglutathione hydrolase activity [Evidence IEA]
GO:0046292 - formaldehyde metabolic process [Evidence IEA]
alcohol + nad(+) = an aldehyde or ketone + nadh
COORDINATES: similar to AA sequence:RefSeq:WP_009100342.1
GO:0004024 - alcohol dehydrogenase activity, zinc-dependent [Evidence IEA]; GO:0051903 - S-(hydroxymethyl)glutathione dehydrogenase activity [Evidence IEA]
GO:0006113 - fermentation [Evidence IEA]; GO:0009404 - toxin metabolic process [Evidence IEA]
S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase
COORDINATES: similar to AA sequence:RefSeq:WP_007148345.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151379.1
GO:0016787 - hydrolase activity [Evidence IEA]
GO:0008152 - metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150656.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150803.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587420.1
COORDINATES: similar to AA sequence:RefSeq:WP_014992502.1
GO:0007155 - cell adhesion [Evidence IEA]
COORDINATES: protein motif:HMM:NF012565.2
COORDINATES: protein motif:HMM:NF012786.2
fimbria/pilus outer membrane usher protein
COORDINATES: similar to AA sequence:RefSeq:WP_014992499.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587425.1
GO:0015379 - potassium:chloride symporter activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_016855184.1
GO:0005886 - plasma membrane [Evidence IEA]
GO:0015079 - potassium ion transmembrane transporter activity [Evidence IEA]
GO:0006813 - potassium ion transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008928952.1
GO:0003723 - RNA binding [Evidence IEA]; GO:0008649 - rRNA methyltransferase activity [Evidence IEA]
GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]; GO:0001510 - RNA methylation [Evidence IEA]; GO:0006364 - rRNA processing [Evidence IEA]
16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB
COORDINATES: similar to AA sequence:RefSeq:WP_011587428.1
GO:0004479 - methionyl-tRNA formyltransferase activity [Evidence IEA]
GO:0006431 - methionyl-tRNA aminoacylation [Evidence IEA]
required for the removal of the formyl group at the N-terminus of nascent polypeptide chains: converts N-formyl-L-methionine to formate + L-methionine
COORDINATES: similar to AA sequence:RefSeq:WP_011587429.1
GO:0042586 - peptide deformylase activity [Evidence IEA]
GO:0036211 - protein modification process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008928955.1
LysM peptidoglycan-binding domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_007149770.1
GO:0009294 - DNA-mediated transformation [Evidence IEA]
translation factor, this domain has been shown to preferentially bind to dsRNA
COORDINATES: similar to AA sequence:RefSeq:WP_011587432.1
GO:0061710 - L-threonylcarbamoyladenylate synthase [Evidence IEA]
GO:0006400 - tRNA modification [Evidence IEA]
coproporphyrinogen-iii + o(2) = protoporphyrinogen-ix + 2 co(2).
COORDINATES: similar to AA sequence:RefSeq:WP_007150863.1
GO:0004109 - coproporphyrinogen oxidase activity [Evidence IEA]
GO:0006779 - porphyrin-containing compound biosynthetic process [Evidence IEA]
oxygen-dependent coproporphyrinogen oxidase
shikimate + NADP(+) = 5-dehydroshikimate + NADPH.
COORDINATES: similar to AA sequence:RefSeq:WP_011587434.1
GO:0004764 - shikimate 3-dehydrogenase (NADP+) activity [Evidence IEA]
GO:0019632 - shikimate metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149358.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151280.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149149.1
may play a specific role in the degradation of signal peptides after they are released from precursor forms of secreted proteins. can cleave N-acetyl-L-ala4. hydrolysis of oligopeptides, with broad specificity. gly or ala commonly occur as p1 or p1' residues, but more distant residues are also important, as is shown by the fact that z-gly-pro-gly-|-gly-pro-ala is cleaved, but not z-(gly)5.
COORDINATES: similar to AA sequence:RefSeq:WP_011587438.1
GO:0004222 - metalloendopeptidase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150347.1
YheV family putative metal-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_008929838.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929837.1
COORDINATES: similar to AA sequence:RefSeq:WP_014992515.1
COORDINATES: similar to AA sequence:RefSeq:WP_014992516.1
proposed to catalyze the late steps in adenosylcobalamin biosynthesis, which define the nucleotide loop assembly pathway.
COORDINATES: protein motif:HMM:TIGR00317.1
GO:0008818 - cobalamin 5'-phosphate synthase activity [Evidence IEA]
GO:0009236 - cobalamin biosynthetic process [Evidence IEA]
adenosylcobinamide-GDP ribazoletransferase
catalyze the reversible hydration of alpha, beta-unsaturated enoyl-CoA substrates to the corresponding beta-hydroxyacyl-CoA products
COORDINATES: similar to AA sequence:RefSeq:WP_007150208.1
crotonase/enoyl-CoA hydratase family protein
COORDINATES: protein motif:HMM:NF016056.2
COORDINATES: similar to AA sequence:RefSeq:WP_019555988.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929925.1
COG: ABC-type Zn2+ transport system, periplasmic component/surface adhesin
COORDINATES: similar to AA sequence:RefSeq:WP_008929923.1
zinc ABC transporter substrate-binding protein
COG: ABC-type Mn/Zn transport systems, ATPase component
COORDINATES: similar to AA sequence:RefSeq:WP_011587453.1
GO:0015633 - ABC-type zinc transporter activity [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA]
GO:0006829 - zinc ion transport [Evidence IEA]
zinc ABC transporter ATP-binding protein ZnuC
COORDINATES: similar to AA sequence:RefSeq:WP_008929921.1
GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]
zinc ABC transporter permease subunit ZnuB
COORDINATES: similar to AA sequence:RefSeq:WP_007151032.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929919.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151198.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929916.1
rubredoxin and rubredoxin reductase (reduces rubredoxin + nad(+) = oxidized rubredoxin + nadh)
COORDINATES: similar to AA sequence:RefSeq:WP_008929915.1
rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. its single fe, chelated to 4 cys, functions as an electron acceptor and may also stabilize the conformation of the molecul
COORDINATES: similar to AA sequence:RefSeq:WP_008929914.1
catalyses the first step in ubiquinone synthesis, i.e. the removal of pyruvate from chorismate, to yield 4-hydroxybenzoate.
COORDINATES: similar to AA sequence:RefSeq:WP_011587461.1
GO:0008813 - chorismate lyase activity [Evidence IEA]
GO:0006744 - ubiquinone biosynthetic process [Evidence IEA]
catalyzes the attachment of prenyl lipid anchors to the carboxyl termini of a variety of proteins.
COORDINATES: similar to AA sequence:RefSeq:WP_007150007.1
GO:0008412 - 4-hydroxybenzoate octaprenyltransferase activity [Evidence IEA]
This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by phoB and phoR when phosphate is limited.
COORDINATES: similar to AA sequence:RefSeq:WP_007148894.1
GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; GO:0000156 - phosphorelay response regulator activity [Evidence IEA]
GO:0006796 - phosphate-containing compound metabolic process [Evidence IEA]; GO:0000160 - phosphorelay signal transduction system [Evidence IEA]; GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]
phosphate regulon transcriptional regulator PhoB
Member of the two-component regulatory system phoR/phoB involved in the phosphate regulon genes expression. phoR may function as a membrane-associated protein kinase that phosphorylates phoB in response to environmental signals.
COORDINATES: similar to AA sequence:RefSeq:WP_011587464.1
GO:0000155 - phosphorelay sensor kinase activity [Evidence IEA]
GO:0006796 - phosphate-containing compound metabolic process [Evidence IEA]; GO:0000160 - phosphorelay signal transduction system [Evidence IEA]
phosphate regulon sensor histidine kinase PhoR
COORDINATES: similar to AA sequence:RefSeq:WP_007148934.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0003678 - DNA helicase activity [Evidence IEA]; GO:0003676 - nucleic acid binding [Evidence IEA]
GO:0006310 - DNA recombination [Evidence IEA]; GO:0006281 - DNA repair [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007151432.1
hydrogen peroxide-inducible genes activator
COORDINATES: similar to AA sequence:RefSeq:WP_007150471.1
Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase
COORDINATES: similar to AA sequence:RefSeq:WP_011587468.1
GO:0009320 - phosphoribosylaminoimidazole carboxylase complex [Evidence IEA]
GO:0004638 - phosphoribosylaminoimidazole carboxylase activity [Evidence IEA]
GO:0009152 - purine ribonucleotide biosynthetic process [Evidence IEA]
5-(carboxyamino)imidazole ribonucleotide mutase
Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)
COORDINATES: similar to AA sequence:RefSeq:WP_007151533.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150950.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151378.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587472.1
Guanosine polyphosphate pyrophosphohydrolases
COORDINATES: similar to AA sequence:RefSeq:WP_008928980.1
GO:0015969 - guanosine tetraphosphate metabolic process [Evidence IEA]; GO:0015968 - stringent response [Evidence IEA]
Catalyses DNA-template-directed extension of the 3'- end of an RNA strand by one nucleotide at a time. Can initiate a chain de novo
COORDINATES: similar to AA sequence:RefSeq:WP_011587474.1
GO:0000345 - cytosolic DNA-directed RNA polymerase complex [Evidence IEA]
GO:0003899 - DNA-directed 5'-3' RNA polymerase activity [Evidence IEA]
GO:0006351 - DNA-templated transcription [Evidence IEA]
DNA-directed RNA polymerase subunit omega
catalyzes the ATP-dependent phosphorylation of GMP into GDP
COORDINATES: similar to AA sequence:RefSeq:WP_011587475.1
GO:0004385 - guanylate kinase activity [Evidence IEA]
GO:0015949 - nucleobase-containing small molecule interconversion [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011587476.1
GO:0042400 - ectoine catabolic process [Evidence IEA]
N(2)-acetyl-L-2,4-diaminobutanoate deacetylase DoeB
2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H(2)O.
COORDINATES: similar to AA sequence:RefSeq:WP_010626859.1
GO:0004160 - dihydroxy-acid dehydratase activity [Evidence IEA]
GO:0009097 - isoleucine biosynthetic process [Evidence IEA]; GO:0009099 - valine biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_014994388.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150864.1
BtrH N-terminal domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_008930250.1
COORDINATES: similar to AA sequence:RefSeq:WP_020581007.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150215.1
GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; GO:0016627 - oxidoreductase activity, acting on the CH-CH group of donors [Evidence IEA]
catalyzes the first step in oxidation of fatty acids
COORDINATES: similar to AA sequence:RefSeq:WP_007150528.1
COORDINATES: similar to AA sequence:RefSeq:WP_008737090.1
GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]
GMC family oxidoreductase N-terminal domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_008930245.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150445.1
SDR family NAD(P)-dependent oxidoreductase
COORDINATES: similar to AA sequence:RefSeq:WP_011587487.1
COORDINATES: protein motif:HMM:NF023568.2
COORDINATES: similar to AA sequence:RefSeq:WP_007149059.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930241.1
outer membrane protein transport protein
COORDINATES: similar to AA sequence:RefSeq:WP_007149384.1
hydrolysis of water soluble or insoluble esters, including triglycerides
COORDINATES: similar to AA sequence:RefSeq:WP_007150424.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930238.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150490.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151233.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930235.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930234.1
GO:0009055 - electron transfer activity [Evidence IEA]; GO:0051536 - iron-sulfur cluster binding [Evidence IEA]
2Fe-2S iron-sulfur cluster-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_008930233.1
GO:0020037 - heme binding [Evidence IEA]; GO:0005506 - iron ion binding [Evidence IEA]; GO:0016705 - oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011587484.1
acting on iron-sulfur proteins as donors with NAD+ or NADP+ as acceptor
COORDINATES: similar to AA sequence:RefSeq:WP_008930231.1
GO:0016491 - oxidoreductase activity [Evidence IEA]
COORDINATES: protein motif:HMM:NF013961.2
COORDINATES: similar to AA sequence:RefSeq:WP_007148507.1
{trna}(n+1) + phosphate = {trna}(n) + a nucleoside diphosphate
COORDINATES: similar to AA sequence:RefSeq:WP_009584291.1
GO:0004549 - tRNA-specific ribonuclease activity [Evidence IEA]
GO:0008033 - tRNA processing [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149443.1
GO:0004588 - orotate phosphoribosyltransferase activity [Evidence IEA]
GO:0009220 - pyrimidine ribonucleotide biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007151105.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149303.1
GO:0010974 - negative regulation of division septum assembly [Evidence IEA]
ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate 5-phosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_011587507.1
GO:0003991 - acetylglutamate kinase activity [Evidence IEA]
GO:0006592 - ornithine biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010630186.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587509.1
GO:0004170 - dUTP diphosphatase activity [Evidence IEA]; GO:0000287 - magnesium ion binding [Evidence IEA]
GO:0006226 - dUMP biosynthetic process [Evidence IEA]; GO:0046081 - dUTP catabolic process [Evidence IEA]
flavoprotein affecting synthesis of dna and pantothenate metabolism
COORDINATES: similar to AA sequence:RefSeq:WP_008928994.1
GO:0004632 - phosphopantothenate--cysteine ligase activity [Evidence IEA]; GO:0004633 - phosphopantothenoylcysteine decarboxylase activity [Evidence IEA]
GO:0015937 - coenzyme A biosynthetic process [Evidence IEA]; GO:0015939 - pantothenate metabolic process [Evidence IEA]
bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC
COORDINATES: similar to AA sequence:RefSeq:WP_008928995.1
COORDINATES: similar to AA sequence:RefSeq:YP_004997628.1
GO:0022625 - cytosolic large ribosomal subunit [Evidence IEA]; GO:0000311 - plastid large ribosomal subunit [Evidence IEA]
GO:0003735 - structural constituent of ribosome [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_001051801.1
GO:0022625 - cytosolic large ribosomal subunit [Evidence IEA]; GO:0000315 - organellar large ribosomal subunit [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_014992562.1
COORDINATES: similar to AA sequence:RefSeq:WP_014992563.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929001.1
pilus assembly protein N-terminal domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_008929002.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929003.1
COORDINATES: similar to AA sequence:RefSeq:WP_014992567.1
type II secretion system F family protein
COORDINATES: similar to AA sequence:RefSeq:WP_008929005.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929006.1
COORDINATES: similar to AA sequence:RefSeq:WP_014992570.1
COORDINATES: protein motif:HMM:NF024792.2
pilus assembly protein TadG-related protein
COORDINATES: similar to AA sequence:RefSeq:WP_076612136.1
frameshifted; internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_007151050.1
COORDINATES: similar to AA sequence:RefSeq:WP_018918086.1
High-affinity uptake of choline driven by a proton- motive force. Pathway: osmoregulatory choline-glycine betaine pathway.
COORDINATES: similar to AA sequence:RefSeq:WP_007149994.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151129.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149668.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151481.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151256.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148570.1
GO:0015297 - antiporter activity [Evidence IEA]
GO:0006814 - sodium ion transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011587535.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587536.1
GO:0009055 - electron transfer activity [Evidence IEA]; GO:0020037 - heme binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149075.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150018.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148686.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149155.1
helix-turn-helix domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_007151508.1
GO:0008324 - monoatomic cation transmembrane transporter activity [Evidence IEA]
GO:0006812 - monoatomic cation transport [Evidence IEA]; GO:0055085 - transmembrane transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149068.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928611.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149837.1
GO:0005215 - transporter activity [Evidence IEA]
efflux RND transporter periplasmic adaptor subunit
responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes.
COORDINATES: similar to AA sequence:RefSeq:WP_011587545.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148796.1
GO:0009279 - cell outer membrane [Evidence IEA]
GO:0015288 - porin activity [Evidence IEA]
efflux transporter outer membrane subunit
COORDINATES: similar to AA sequence:RefSeq:WP_007016711.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149158.1
CbiX/SirB N-terminal domain-containing protein
Formation of acetoacetyl-CoA from two molecules of acetyl-CoA.
COORDINATES: similar to AA sequence:RefSeq:WP_007148333.1
GO:0016746 - acyltransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_014992843.1
ATP-binding cassette domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_008928591.1
s-adenosyl-l-methionine + 8-amino-7-oxononanoate = s-adenosyl-4-methylthio-2-oxobutanoate + 7,8- diaminononanoate
COORDINATES: similar to AA sequence:RefSeq:WP_007150651.1
GO:0004015 - adenosylmethionine-8-amino-7-oxononanoate transaminase activity [Evidence IEA]; GO:0030170 - pyridoxal phosphate binding [Evidence IEA]
GO:0009102 - biotin biosynthetic process [Evidence IEA]
adenosylmethionine--8-amino-7-oxononanoate transaminase
COORDINATES: similar to AA sequence:RefSeq:WP_007149274.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148505.1
FKBP-type peptidyl-prolyl cis-trans isomerase
COORDINATES: similar to AA sequence:RefSeq:WP_007149591.1
GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007151085.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587557.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587558.1
catalytic activity ATP + l-glutamate + l-cysteine = ADP + phosphate + gamma-l-glutamyl-l-cysteine.
COORDINATES: similar to AA sequence:RefSeq:WP_011587559.1
GO:0004357 - glutamate-cysteine ligase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148410.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150289.1
unctions as a cation/drug antiporter (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_007151507.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148957.1
HlyD family efflux transporter periplasmic adaptor subunit
Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COORDINATES: protein motif:HMM:NF007005.1
GO:0000160 - phosphorelay signal transduction system [Evidence IEA]; GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]
two-component system response regulator OmpR
Member of the two-component regulatory system envZ/ompR involved in the regulation of osmoregulation (genes ompF & ompC). EnvZ functions as a membrane-associated protein kinase that phosphorylates ompR in response to environmental signals.
COORDINATES: similar to AA sequence:RefSeq:WP_007150769.1
catalyzes the cleavage of the glycosidic bonds between n-acetylmuramic acid and n- acetylglucosamine residues in peptidoglycan
COORDINATES: similar to AA sequence:RefSeq:WP_007150633.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150526.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587568.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150093.1
YihY/virulence factor BrkB family protein
transfer of electrons from nadh to the respiratory chain. the immediate electron acceptor for the enzyme is believed to be ubiquinone. does not couple the redox reaction to proton translocation
COORDINATES: similar to AA sequence:RefSeq:WP_007148839.1
atp + oxaloacetate = adp + phosphoenolpyruvate + co(2)
COORDINATES: similar to AA sequence:RefSeq:WP_011587571.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0004611 - phosphoenolpyruvate carboxykinase activity [Evidence IEA]; GO:0017076 - purine nucleotide binding [Evidence IEA]
GO:0006094 - gluconeogenesis [Evidence IEA]
Disulfide bond chaperones of the HSP33 family
COORDINATES: similar to AA sequence:RefSeq:WP_011587572.1
GO:0051082 - unfolded protein binding [Evidence IEA]
GO:0006457 - protein folding [Evidence IEA]
Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit
COORDINATES: similar to AA sequence:RefSeq:WP_007149216.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150574.1
active on adenosine(5')triphospho(5')adenosine (ap3a), adp-ribose, nadh, adenosine(5')diphospho(5')adenosine (ap2a) (adp-ribose + h(2)o = amp + d-ribose 5- phosphate)
COORDINATES: similar to AA sequence:RefSeq:WP_011587575.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928548.1
GO:0008441 - 3'(2'),5'-bisphosphate nucleotidase activity [Evidence IEA]
GO:0006790 - sulfur compound metabolic process [Evidence IEA]
3'(2'),5'-bisphosphate nucleotidase CysQ
COORDINATES: similar to AA sequence:RefSeq:WP_007148861.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150046.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587579.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150640.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149869.1
COORDINATES: similar to AA sequence:RefSeq:WP_008734866.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150365.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927513.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151629.1
COORDINATES: similar to AA sequence:RefSeq:WP_019017717.1
COORDINATES: similar to AA sequence:RefSeq:WP_010322574.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0016887 - ATP hydrolysis activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150560.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927446.1
catalyzes the last step in heme biosynthesis: the chelation of a ferrous ion to proto-porphyrin IX, to form protoheme (protoporphyrin + fe(2+) = protoheme + 2 h(+))
COORDINATES: similar to AA sequence:RefSeq:WP_011587590.1
GO:0004325 - ferrochelatase activity [Evidence IEA]
isocitrate + NADP(+) = 2-oxoglutarate + CO(2) + NADPH.
COORDINATES: similar to AA sequence:RefSeq:WP_011587592.1
GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010324760.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587594.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150624.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149633.1
saccharopine dehydrogenase NADP-binding domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_007151005.1
It oxidizes pyridoxamine-5-P (PMP) and pyridoxine-5-P (PNP) to pyridoxal-5-P
COORDINATES: similar to AA sequence:RefSeq:WP_011587598.1
GO:0010181 - FMN binding [Evidence IEA]; GO:0004733 - pyridoxamine-phosphate oxidase activity [Evidence IEA]
GO:0008615 - pyridoxine biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_000116330.1
GO:0015074 - DNA integration [Evidence IEA]; GO:0006310 - DNA recombination [Evidence IEA]
frameshifted; incomplete; partial in the middle of a contig; missing N-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: protein motif:HMM:NF037531.2
COORDINATES: nucleotide motif:Rfam:14.4:RF00023
Derived by automated computational analysis using gene prediction method: cmsearch.
COORDINATES: similar to AA sequence:RefSeq:WP_014996195.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149529.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150506.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587603.1
may have a structural role in maintaining the cell envelope integrity
COORDINATES: similar to AA sequence:RefSeq:WP_007151389.1
outer membrane protein assembly factor BamE
COORDINATES: similar to AA sequence:RefSeq:WP_008927875.1
GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]
ferric iron uptake transcriptional regulator
COORDINATES: similar to AA sequence:RefSeq:WP_007150933.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150836.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148673.1
GO:0009408 - response to heat [Evidence IEA]
heat-inducible transcriptional repressor HrcA
The GrpE protein functions with the DnaK and DnaJ proteins to prevent the aggregation of newly synthesized proteins and of unfolded proteins that arise as a consequence of cell stress.
COORDINATES: similar to AA sequence:RefSeq:WP_008927871.1
GO:0000774 - adenyl-nucleotide exchange factor activity [Evidence IEA]; GO:0051087 - chaperone binding [Evidence IEA]; GO:0042803 - protein homodimerization activity [Evidence IEA]
The DnaK protein functions with the GrpE and DnaJ proteins to prevent the aggregation of newly synthesized proteins and of unfolded proteins that arise as a consequence of cell stress.
COORDINATES: similar to AA sequence:RefSeq:WP_011587610.1
The DnaJ protein functions with the GrpE and DnaK proteins to prevent the aggregation of newly synthesized proteins and of unfolded proteins that arise as a consequence of cell stress.
COORDINATES: similar to AA sequence:RefSeq:WP_011587611.1
GO:0005515 - protein binding [Evidence IEA]
GO:0006457 - protein folding [Evidence IEA]; GO:0009408 - response to heat [Evidence IEA]
2,3,4,5-tetrahydrodipicolinate + NAD(P)(+) = 2,3-dihydrodipicolinate + NAD(P)H.
COORDINATES: similar to AA sequence:RefSeq:WP_011587612.1
GO:0008839 - 4-hydroxy-tetrahydrodipicolinate reductase [Evidence IEA]
GO:0009089 - lysine biosynthetic process via diaminopimelate [Evidence IEA]
4-hydroxy-tetrahydrodipicolinate reductase
2 ATP + L-glutamine + CO(2) + H(2)O = 2 ADP + phosphate + L-glutamate + carbamoyl phosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_008927866.1
GO:0005951 - carbamoyl-phosphate synthase complex [Evidence IEA]
GO:0004088 - carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [Evidence IEA]
glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit
COORDINATES: similar to AA sequence:RefSeq:WP_007148741.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0046872 - metal ion binding [Evidence IEA]
GO:0006807 - nitrogen compound metabolic process [Evidence IEA]
carbamoyl-phosphate synthase large subunit
COORDINATES: similar to AA sequence:RefSeq:WP_005106333.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0070063 - RNA polymerase binding [Evidence IEA]
GO:0032784 - regulation of DNA-templated transcription elongation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007151514.1
specifically methylates the uridine in position 2552 of 23s rrna in the 50s particle (s-adenosyl-l-methionine + rrna = s-adenosyl-l- homocysteine + rrna containing 2'-o-methyluridine)
COORDINATES: similar to AA sequence:RefSeq:WP_011587617.1
GO:0016436 - rRNA (uridine) methyltransferase activity [Evidence IEA]
GO:0001510 - RNA methylation [Evidence IEA]; GO:0006364 - rRNA processing [Evidence IEA]
23S rRNA (uridine(2552)-2'-O)-methyltransferase RlmE
COORDINATES: similar to AA sequence:RefSeq:WP_007149868.1
GO:0016887 - ATP hydrolysis activity [Evidence IEA]; GO:0004222 - metalloendopeptidase activity [Evidence IEA]
GO:0051301 - cell division [Evidence IEA]; GO:0006508 - proteolysis [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_019019084.1
GO:0004156 - dihydropteroate synthase activity [Evidence IEA]
GO:0009396 - folic acid-containing compound biosynthetic process [Evidence IEA]
catalyses the interconversion of glucosamine-6-phosphate into glucosamine-1-phosphate in the biosynthetic pathway leading to the synthesis of UDP-N-acetylglucosamine
COORDINATES: similar to AA sequence:RefSeq:WP_011587620.1
GO:0016868 - intramolecular transferase activity, phosphotransferases [Evidence IEA]; GO:0000287 - magnesium ion binding [Evidence IEA]; GO:0008966 - phosphoglucosamine mutase activity [Evidence IEA]
d-glyceraldehyde 3-phosphate = glycerone phosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_011587621.1
GO:0004807 - triose-phosphate isomerase activity [Evidence IEA]
GO:0006096 - glycolytic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148694.1
GO:0015450 - protein-transporting ATPase activity [Evidence IEA]
GO:0043952 - protein transport by the Sec complex [Evidence IEA]
Derived by automated computational analysis using gene prediction method: tRNAscan-SE.
COORDINATES: similar to AA sequence:RefSeq:WP_007149481.1
GO:0042274 - ribosomal small subunit biogenesis [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149886.1
GO:0006353 - DNA-templated transcription termination [Evidence IEA]
protects formylmethionyl-trna from spontaneous hydrolysis and promotes its binding to the 30s ribosomal subunits. also involved in the hydrolysis of gtp during the formation of the 70s ribosomal complex
COORDINATES: similar to AA sequence:RefSeq:WP_011587625.1
GO:0003743 - translation initiation factor activity [Evidence IEA]
GO:0006413 - translational initiation [Evidence IEA]
essential for efficient processing of 16s rrna. may interact with the 5'terminal helix region of 16s rrna
COORDINATES: similar to AA sequence:RefSeq:WP_007151594.1
GO:0019843 - rRNA binding [Evidence IEA]
GO:0006396 - RNA processing [Evidence IEA]
formation of pseudouridine at position 55 in the psi gc loop of transfer rnas (uracil + d-ribose 5-phosphate = pseudouridine 5'-phosphate + h(2)o)
COORDINATES: similar to AA sequence:RefSeq:WP_011587627.1
GO:0004730 - pseudouridylate synthase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:NP_253429.1
GO:0022627 - cytosolic small ribosomal subunit [Evidence IEA]; GO:0000314 - organellar small ribosomal subunit [Evidence IEA]
involved in mrna degradation. hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction ({rna}(n+1) + phosphate = {rna}(n) + a nucleoside diphosphate)
COORDINATES: similar to AA sequence:RefSeq:WP_008927850.1
GO:0004654 - polyribonucleotide nucleotidyltransferase activity [Evidence IEA]
GO:0006402 - mRNA catabolic process [Evidence IEA]
polyribonucleotide nucleotidyltransferase
synthesis of acetyl-CoA from CO, CoA, and a methyl group
COORDINATES: similar to AA sequence:RefSeq:WP_007150380.1
GO:0003987 - acetate-CoA ligase activity [Evidence IEA]
GO:0019427 - acetyl-CoA biosynthetic process from acetate [Evidence IEA]
catalytic activity: l-aspartate = beta-alanine + co(2). cofactor: pyruvoyl group (by similarity). pathway: pantothenate biosynthesis; second branch. similarity belongs to the pand family.
COORDINATES: similar to AA sequence:RefSeq:WP_014996160.1
GO:0004068 - aspartate 1-decarboxylase activity [Evidence IEA]
GO:0006523 - alanine biosynthetic process [Evidence IEA]
atp + (r)-pantoate + beta-alanine = amp + diphosphate + (r)-pantothenate
COORDINATES: similar to AA sequence:RefSeq:WP_011587631.1
GO:0004592 - pantoate-beta-alanine ligase activity [Evidence IEA]
GO:0015940 - pantothenate biosynthetic process [Evidence IEA]
5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate = tetrahydrofolate + 2-dehydropantoate
COORDINATES: similar to AA sequence:RefSeq:WP_007149944.1
GO:0003864 - 3-methyl-2-oxobutanoate hydroxymethyltransferase activity [Evidence IEA]
3-methyl-2-oxobutanoate hydroxymethyltransferase
catalyses production of deoxynucleotide 5'-monophosphate from a deoxynucleoside
COORDINATES: similar to AA sequence:RefSeq:WP_007149499.1
atp + 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine = amp + 2-amino-7,8-dihydro-4-hydroxy-6-(diphosphooxymethyl)pterid ine
COORDINATES: similar to AA sequence:RefSeq:WP_007150944.1
GO:0003848 - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity [Evidence IEA]
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase
COORDINATES: similar to AA sequence:RefSeq:WP_014996155.1
GO:0004652 - polynucleotide adenylyltransferase activity [Evidence IEA]; GO:0003723 - RNA binding [Evidence IEA]
GO:0006378 - mRNA polyadenylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007151319.1
sigma-54 dependent transcriptional regulator
COORDINATES: similar to AA sequence:RefSeq:WP_007148388.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149317.1
COG: Glutamyl- and glutaminyl-tRNA synthetases
COORDINATES: similar to AA sequence:RefSeq:WP_007151120.1
GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]
GO:0043039 - tRNA aminoacylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_016853961.1
GO:0019899 - enzyme binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149626.1
GO:0030170 - pyridoxal phosphate binding [Evidence IEA]
GO:0009058 - biosynthetic process [Evidence IEA]
aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme
The sugar fermentation stimulation protein is a probable regulatory factor involved in maltose metabolism
COORDINATES: similar to AA sequence:RefSeq:WP_011587642.1
GO:0000023 - maltose metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_014996147.1
GO:0004674 - protein serine/threonine kinase activity [Evidence IEA]
GO:0006468 - protein phosphorylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011587644.1
phosphorylates sugars in the presence of ATP and magnesium
COORDINATES: similar to AA sequence:RefSeq:WP_007150470.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149503.1
GO:0009274 - peptidoglycan-based cell wall [Evidence IEA]
GO:0008658 - penicillin binding [Evidence IEA]; GO:0008233 - peptidase activity [Evidence IEA]; GO:0008955 - peptidoglycan glycosyltransferase activity [Evidence IEA]
GO:0009252 - peptidoglycan biosynthetic process [Evidence IEA]; GO:0046677 - response to antibiotic [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007151362.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927826.1
GO:0002161 - aminoacyl-tRNA editing activity [Evidence IEA]
(s)-4-amino-5-oxopentanoate = 5-aminolevulinate
COORDINATES: similar to AA sequence:RefSeq:WP_011587649.1
GO:0042286 - glutamate-1-semialdehyde 2,1-aminomutase activity [Evidence IEA]
glutamate-1-semialdehyde 2,1-aminomutase
COORDINATES: similar to AA sequence:RefSeq:WP_007150544.1
GO:0004789 - thiamine-phosphate diphosphorylase activity [Evidence IEA]
GO:0009228 - thiamine biosynthetic process [Evidence IEA]
catalyzes the phosphorylation of hmp-p to hmp-pp (atp + 4-amino-2-methyl-5- phosphomethylpyrimidine = adp + 4-amino-2-methyl-5- diphosphomethylpyrimidine)
COORDINATES: similar to AA sequence:RefSeq:WP_008927823.1
hydroxymethylpyrimidine/phosphomethylpyrimidine kinase
COORDINATES: similar to AA sequence:RefSeq:WP_011587652.1
COORDINATES: similar to AA sequence:RefSeq:WP_014996137.1
catalyses the NADPH-dependent reduction of N-acetyl-gamma-glutamyl phosphate to give the N-acetylglutamic semialdehyde
COORDINATES: similar to AA sequence:RefSeq:WP_007149102.1
GO:0003942 - N-acetyl-gamma-glutamyl-phosphate reductase activity [Evidence IEA]
N-acetyl-gamma-glutamyl-phosphate reductase
COORDINATES: similar to AA sequence:RefSeq:WP_007149687.1
Integral membrane protein CcmA involved in cell shape determination
COORDINATES: similar to AA sequence:RefSeq:WP_014996135.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149745.1
GO:0051536 - iron-sulfur cluster binding [Evidence IEA]
GO:0016226 - iron-sulfur cluster assembly [Evidence IEA]
iron-sulfur cluster insertion protein ErpA
COORDINATES: similar to AA sequence:RefSeq:WP_007148952.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151196.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0016773 - phosphotransferase activity, alcohol group as acceptor [Evidence IEA]
GO:0006040 - amino sugar metabolic process [Evidence IEA]; GO:0009254 - peptidoglycan turnover [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150429.1
peptidoglycan DD-metalloendopeptidase family protein
atp + l-tyrosine + trna(tyr) = amp + diphosphate + l-tyrosyl-trna(tyr)
COORDINATES: similar to AA sequence:RefSeq:WP_008927813.1
GO:0004831 - tyrosine-tRNA ligase activity [Evidence IEA]
GO:0006437 - tyrosyl-tRNA aminoacylation [Evidence IEA]
COORDINATES: nucleotide motif:Rfam:14.4:RF00177
COORDINATES: nucleotide motif:Rfam:14.4:RF02541
COORDINATES: nucleotide motif:Rfam:14.4:RF00001
catalyses the formation of fatty acyl-CoA
COORDINATES: similar to AA sequence:RefSeq:WP_007150540.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149369.1
GO:0004077 - biotin-[acetyl-CoA-carboxylase] ligase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011587664.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930555.1
GO:0042834 - peptidoglycan binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011911974.1
GO:0003746 - translation elongation factor activity [Evidence IEA]
GO:0006414 - translational elongation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150146.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930479.1
transcription termination/antitermination protein NusG
This protein binds directly to 23S ribosomal RNA.
COORDINATES: similar to AA sequence:RefSeq:WP_008285482.1
This protein binds directly to 23S ribosomal RNA and is located in the neighborhood of the site where elongation factor tu is bound to the ribosome. function protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
COORDINATES: similar to AA sequence:RefSeq:WP_007150884.1
Protein L10 is also a translational repressor protein, it controls the translation of the rpljl-rpoBC operon by binding to its mRNA.
COORDINATES: similar to AA sequence:RefSeq:WP_005339895.1
GO:0015934 - large ribosomal subunit [Evidence IEA]
Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation.
COORDINATES: similar to AA sequence:RefSeq:WP_007149799.1
DNA-directed RNA polymerase beta subunit/140 kD subunit (split gene in Mjan, Mthe, Aful)
COORDINATES: similar to AA sequence:RefSeq:WP_012071943.1
DNA-directed RNA polymerase subunit beta
DNA-directed RNA polymerase beta' subunit/160 kD subunit (split gene in archaea and Syn)
COORDINATES: similar to AA sequence:RefSeq:WP_011587674.1
DNA-directed RNA polymerase subunit beta'
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the a site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, It traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins s8, s12 and s17 appears to hold together the shoulder and platform of the 30S subunit (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_003093744.1
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, where it has been shown to contact mRNA. Probably blocks exit of the e-site tRNA (by similarity). Protein S7 is also a translational repressor protein; it regulates the expression of the str operon members to different degrees by binding to its mRNA.
COORDINATES: similar to AA sequence:RefSeq:WP_003369032.1
This protein promotes the GTP-dependent translocation of the nascent protein chain from the a-site to the p-site of the ribosome.
COORDINATES: similar to AA sequence:RefSeq:WP_014996115.1
produces a precursor for alginate polymerization. gdp-mannose + 2 nad(+) + h(2)o = gdp-d-mannuronate + 2 nadh.
COORDINATES: similar to AA sequence:RefSeq:WP_008928831.1
UDP-glucose/GDP-mannose dehydrogenase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_008928832.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928833.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928834.1
Involved in the export of the exopolysaccharide alginate
COORDINATES: similar to AA sequence:RefSeq:WP_008928835.1
AlgI is involved in acetylation of the alginate polymer.
COORDINATES: similar to AA sequence:RefSeq:WP_008928836.1
AlgJ is involved in acetylation of the alginate polymer
COORDINATES: similar to AA sequence:RefSeq:WP_008928837.1
AlgF is involved in acetylation of the alginate polymer
COORDINATES: similar to AA sequence:RefSeq:WP_008928838.1
COORDINATES: protein motif:HMM:NF028132.2
COORDINATES: similar to AA sequence:RefSeq:WP_008928840.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928841.1
right-handed parallel beta-helix repeat-containing protein
produces a precursor for alginate polymerization. catalitic activity: d-mannose 6-phosphate = d-fructose 6- phosphate. gdp + d-mannose 1-phosphate = phosphate + gdp- mannose.
COORDINATES: similar to AA sequence:RefSeq:WP_008928842.1
GO:0004476 - mannose-6-phosphate isomerase activity [Evidence IEA]
GO:0009103 - lipopolysaccharide biosynthetic process [Evidence IEA]
mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase
COORDINATES: similar to AA sequence:RefSeq:WP_014268624.1
GO:0003723 - RNA binding [Evidence IEA]; GO:0003735 - structural constituent of ribosome [Evidence IEA]
This protein binds directly to 23S ribosomal RNA and may participate in the formation of the peptidyltransferase center of the ribosome.
COORDINATES: similar to AA sequence:RefSeq:WP_011587690.1
This protein binds directly and specifically to 23S rRNA. Protein L4 is also a translational repressor protein, it controls the translation of the S10 operon (to which belong L4) by binding to its mRNA
COORDINATES: similar to AA sequence:RefSeq:WP_009723903.1
GO:0022625 - cytosolic large ribosomal subunit [Evidence IEA]
Binds to a specific region on the 23S rRNA.
COORDINATES: similar to AA sequence:RefSeq:WP_011587692.1
This protein is a primary 23S rRNA-binding protein. It has peptidyltransferase activity.
COORDINATES: similar to AA sequence:RefSeq:NP_312209.1
COORDINATES: similar to AA sequence:RefSeq:NP_252949.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149326.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149325.1
GO:0022627 - cytosolic small ribosomal subunit [Evidence IEA]; GO:0000312 - plastid small ribosomal subunit [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_017805229.1
COORDINATES: similar to AA sequence:RefSeq:WP_010626474.1
Protein S17 binds specifically to the 5' end of 16s ribosomal RNA. S17 is thought to be involved in the recognition of termination codons.
COORDINATES: similar to AA sequence:RefSeq:WP_011587695.1
COORDINATES: similar to AA sequence:RefSeq:WP_012728338.1
This protein is found in the ribonucleoprotein core and is involved in the early assembly of the 50S subunit. It is not involved in the functions of the mature 50S subunit.
COORDINATES: similar to AA sequence:RefSeq:WP_011587696.1
This is one of 3 proteins that mediate the attachment of the 5S RNA into the large ribosomal subunit.
COORDINATES: similar to AA sequence:RefSeq:WP_007151080.1
Known to be required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16s rRNA at the a site.
COORDINATES: similar to AA sequence:RefSeq:WP_003400428.1
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
COORDINATES: similar to AA sequence:RefSeq:WP_011587699.1
This protein binds directly to 23S ribosomal RNA and is located at the aminoacyl-tRNA binding site of the peptidyltransferase center.
COORDINATES: similar to AA sequence:RefSeq:WP_014996097.1
GO:0019843 - rRNA binding [Evidence IEA]; GO:0003735 - structural constituent of ribosome [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011399904.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928861.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149547.1
COORDINATES: similar to AA sequence:RefSeq:WP_011505748.1
Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel. subunit one of seven secretory proteins (seca-f & secy) that comprise the prokaryotic protein translocation apparatus.
COORDINATES: similar to AA sequence:RefSeq:WP_011587704.1
COORDINATES: similar to AA sequence:RefSeq:WP_002555468.1
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the E.coli 70S ribosome it has been modeled to contact the 23S rRNA (bridge b1a) and protein L5 of the 50S subunit (bridge b1b), connecting the 2 subunits; these bridges are implicated in subunit movement. contacts the tRNAs in the a and p-sites. Subunit: part of the 30S ribosomal subunit. forms a loose heterodimer with protein S19. forms two bridges to the 50S subunit in the 70S ribosome.
COORDINATES: similar to AA sequence:RefSeq:NP_252931.1
GO:0022627 - cytosolic small ribosomal subunit [Evidence IEA]
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. forms part of the shine-dalgarno cleft in the 70S ribosome. Subunit: part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Cross-links to if-3.
COORDINATES: similar to AA sequence:RefSeq:WP_001029758.1
One of two assembly initiator proteins for the 30S subunit, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. With S5 and S12 plays an important role in translational accuracy; many suppressors of streptomycin-dependent mutants of protein S12 are found in this protein, some but not all of which decrease translational accuracy (ram, ribosomal ambiguity mutations).
Protein S4 is also a translational repressor protein, it controls the translation of the alpha-operon (which codes for S13, S11, S4, RNA polymerase alpha subunit, and L17) by binding to its mRNA. Also functions as a rho-dependent antiterminator of rRNA transcription, increasing the synthesis of rRNA under conditions of excess protein, allowing a more rapid return to homeostasis. Binds directly to RNA polymerase.
COORDINATES: similar to AA sequence:RefSeq:WP_011399896.1
GO:0015935 - small ribosomal subunit [Evidence IEA]
DNA-directed RNA polymerase alpha subunit/40 kD subunit
COORDINATES: similar to AA sequence:RefSeq:WP_007150795.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0003899 - DNA-directed 5'-3' RNA polymerase activity [Evidence IEA]; GO:0046983 - protein dimerization activity [Evidence IEA]
DNA-directed RNA polymerase subunit alpha
COORDINATES: similar to AA sequence:RefSeq:WP_011587709.1
GO:0022625 - cytosolic large ribosomal subunit [Evidence IEA]; GO:0005762 - mitochondrial large ribosomal subunit [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008928871.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928873.1
COORDINATES: similar to AA sequence:RefSeq:WP_010629931.1
glycerophosphodiester phosphodiesterase family protein
the uvrabc repair system catalyzes the recognition and processing of DNA lesions. uvra is an ATPase and a DNA-binding protein. a damage recognition complex composed of 2 uvra and 2 uvrb subunits scans DNA for abnormalities. when the presence of a lesion has been verified by uvrb, the uvra molecules dissociate.
COORDINATES: similar to AA sequence:RefSeq:WP_011587713.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0016887 - ATP hydrolysis activity [Evidence IEA]; GO:0003677 - DNA binding [Evidence IEA]
GO:0006289 - nucleotide-excision repair [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148438.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151147.1
This protein is essential for replication of the chromosomes and its single-stranded DNA phages. It is also involved in DNA recombination and repair.
COORDINATES: similar to AA sequence:RefSeq:WP_007150577.1
GO:0003697 - single-stranded DNA binding [Evidence IEA]
GO:0006310 - DNA recombination [Evidence IEA]; GO:0006281 - DNA repair [Evidence IEA]; GO:0006260 - DNA replication [Evidence IEA]; GO:0006351 - DNA-templated transcription [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150684.1
GO:0015627 - type II protein secretion system complex [Evidence IEA]
GO:0015628 - protein secretion by the type II secretion system [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150017.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151300.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151375.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928882.1
adenylate/guanylate cyclase domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_007150862.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928884.1
nucleoside triphosphate pyrophosphohydrolase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_011587724.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587725.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148627.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151286.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928895.1
hybrid sensor histidine kinase/response regulator
COORDINATES: similar to AA sequence:RefSeq:WP_011587729.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149835.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928898.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928902.1
COORDINATES: similar to AA sequence:RefSeq:WP_014996053.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928905.1
CPXCG motif-containing cysteine-rich protein
COORDINATES: similar to AA sequence:RefSeq:WP_008928907.1
COORDINATES: similar to AA sequence:RefSeq:WP_014996050.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149285.1
GO:0008299 - isoprenoid biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148862.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149973.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587740.1
GO:0042254 - ribosome biogenesis [Evidence IEA]
catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5-oxoproline. ATP + L-glutamate = ADP + L-glutamate 5-phosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_011587741.1
GO:0004349 - glutamate 5-kinase activity [Evidence IEA]
GO:0006561 - proline biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008928914.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148886.1
GO:0034204 - lipid translocation [Evidence IEA]; GO:0009252 - peptidoglycan biosynthetic process [Evidence IEA]
murein biosynthesis integral membrane protein MurJ
atp + riboflavin = adp + fmn / atp + fmn = diphosphate + fad
COORDINATES: similar to AA sequence:RefSeq:WP_007150098.1
GO:0003919 - FMN adenylyltransferase activity [Evidence IEA]
bifunctional riboflavin kinase/FAD synthetase
atp + l-isoleucine + trna(ile) = amp + diphosphate + l-isoleucyl-trna(ile).
COORDINATES: similar to AA sequence:RefSeq:WP_008928917.1
GO:0004822 - isoleucine-tRNA ligase activity [Evidence IEA]
GO:0006428 - isoleucyl-tRNA aminoacylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007151163.1
GO:0004190 - aspartic-type endopeptidase activity [Evidence IEA]
GO:0009306 - protein secretion [Evidence IEA]; GO:0006508 - proteolysis [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150396.1
GO:0003755 - peptidyl-prolyl cis-trans isomerase activity [Evidence IEA]
catalyses the conversion of 1-hydroy-2-methyl-2-(E)-butenyl 4-diphosphate into IPP (isopentenyl diphosphate) and DMAPP (dimethylallyl diphosphate)
COORDINATES: similar to AA sequence:RefSeq:WP_007150942.1
GO:0051745 - 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity [Evidence IEA]; GO:0046872 - metal ion binding [Evidence IEA]
GO:0050992 - dimethylallyl diphosphate biosynthetic process [Evidence IEA]; GO:0019288 - isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [Evidence IEA]
4-hydroxy-3-methylbut-2-enyl diphosphate reductase
COORDINATES: similar to AA sequence:RefSeq:WP_007150673.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150959.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150709.1
GO:0043683 - type IV pilus assembly [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148366.1
PilX N-terminal domain-containing pilus assembly protein
COORDINATES: protein motif:HMM:NF017388.2
COORDINATES: similar to AA sequence:RefSeq:WP_008928926.1
COORDINATES: protein motif:HMM:NF023444.2
COORDINATES: similar to AA sequence:RefSeq:WP_008928928.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148328.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150889.1
HAMP domain-containing sensor histidine kinase
COORDINATES: similar to AA sequence:RefSeq:WP_007149672.1
catalyzes the last step in the biosynthesis of nicotinamide adenine dinucleotide and is induced by stress factors such as heat shock and glucose limitation
COORDINATES: similar to AA sequence:RefSeq:WP_008928931.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0003952 - NAD+ synthase (glutamine-hydrolyzing) activity [Evidence IEA]
GO:0009435 - NAD biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148454.1
outer membrane protein assembly factor BamD
responsible for synthesis of pseudouridine from uracil at two positions in 23s ribosomal RNA (uracil + d-ribose 5-phosphate = pseudouridine 5'-phosphate + H(2)O
COORDINATES: similar to AA sequence:RefSeq:WP_014996024.1
GO:0009982 - pseudouridine synthase activity [Evidence IEA]; GO:0003723 - RNA binding [Evidence IEA]
GO:0001522 - pseudouridine synthesis [Evidence IEA]; GO:0009451 - RNA modification [Evidence IEA]
23S rRNA pseudouridine(1911/1915/1917) synthase RluD
COORDINATES: similar to AA sequence:RefSeq:WP_007149701.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928935.1
GO:0042026 - protein refolding [Evidence IEA]; GO:0009408 - response to heat [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148357.1
COORDINATES: similar to AA sequence:RefSeq:WP_014996019.1
GO:0003984 - acetolactate synthase activity [Evidence IEA]; GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; GO:0000287 - magnesium ion binding [Evidence IEA]; GO:0030976 - thiamine pyrophosphate binding [Evidence IEA]
GO:0009082 - branched-chain amino acid biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_005757070.1
GO:1990610 - acetolactate synthase regulator activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011395256.1
COORDINATES: similar to AA sequence:RefSeq:WP_010627683.1
COORDINATES: similar to AA sequence:RefSeq:WP_011399623.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151102.1
GO:0003882 - CDP-diacylglycerol-serine O-phosphatidyltransferase activity [Evidence IEA]
GO:0008654 - phospholipid biosynthetic process [Evidence IEA]
CDP-diacylglycerol--serine O-phosphatidyltransferase
COORDINATES: protein motif:HMM:NF015142.2
COORDINATES: similar to AA sequence:RefSeq:WP_007150722.1
GO:0005575 - cellular_component [Evidence IEA]
GO:0001727 - lipid kinase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007151059.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149631.1
COORDINATES: similar to AA sequence:RefSeq:WP_007018924.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150891.1
GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA]; GO:0000166 - nucleotide binding [Evidence IEA]; GO:0004832 - valine-tRNA ligase activity [Evidence IEA]
GO:0006438 - valyl-tRNA aminoacylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149488.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149654.1
presumably involved in the processing and regular turnover of intracellular proteins. catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. release of an N-terminal amino acid, xaa-|- xbb-, in which xaa is preferably leu, but may be other amino acids including pro although not arg or lys, and xbb may be pro.
COORDINATES: similar to AA sequence:RefSeq:WP_011587781.1
GO:0070006 - metalloaminopeptidase activity [Evidence IEA]
GO:0019538 - protein metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149372.1
GO:0015221 - lipopolysaccharide transmembrane transporter activity [Evidence IEA]
GO:0015920 - lipopolysaccharide transport [Evidence IEA]
LPS export ABC transporter permease LptF
COORDINATES: similar to AA sequence:RefSeq:WP_007149880.1
LPS export ABC transporter permease LptG
COORDINATES: similar to AA sequence:RefSeq:WP_007149781.1
synthesizes oq from preq1 in a single s-adenosylmethionine-requiring step. the ribosyl moiety of adomet is transferred and isomerized to the epoxycyclopentane residue of oq
COORDINATES: similar to AA sequence:RefSeq:WP_011587786.1
GO:0016853 - isomerase activity [Evidence IEA]; GO:0016740 - transferase activity [Evidence IEA]
tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA
COORDINATES: similar to AA sequence:RefSeq:WP_007150620.1
GO:0008479 - queuine tRNA-ribosyltransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150781.1
GO:0009306 - protein secretion [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150143.1
GO:0031522 - cell envelope Sec protein transport complex [Evidence IEA]
Involved in protein export. subunit part of the prokaryotic protein translocation apparatus which comprise secA, secB, secD, secE, secF, secG and secY.
COORDINATES: similar to AA sequence:RefSeq:WP_008738218.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929166.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929167.1
pyridoxal phosphate-dependent aminotransferase
COORDINATES: similar to AA sequence:RefSeq:WP_008929168.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148450.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929170.1
aspartate aminotransferase family protein
tdh has multiple catalytic activities. apart from catalyzing the oxidation of (+)-tartrate to oxaloglycolate, also converts meso-tartrate to D-glycerate and catalyzes the oxidative decarboxylation of D-malate to pyruvate. tartrate + NAD(+) = oxaloglycolate + NADH.
COORDINATES: similar to AA sequence:RefSeq:WP_007150576.1
isocitrate/isopropylmalate dehydrogenase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_016854537.1
NAD-dependent succinate-semialdehyde dehydrogenase
biosynthesis of free myo-inositol from inositol-1-phosphate
COORDINATES: similar to AA sequence:RefSeq:WP_016191584.1
GO:0008934 - inositol monophosphate 1-phosphatase activity [Evidence IEA]
GO:0046855 - inositol phosphate dephosphorylation [Evidence IEA]; GO:0046854 - phosphatidylinositol phosphate biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148326.1
acetyl-CoA + L-serine = CoA + O-acetyl-L-serine.
COORDINATES: similar to AA sequence:RefSeq:WP_008929175.1
GO:0009001 - serine O-acetyltransferase activity [Evidence IEA]
GO:0006535 - cysteine biosynthetic process from serine [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_000506572.1
n-substituted aminoacyl-tRNA + H(2)O = n-substituted amino acid + tRNA
COORDINATES: similar to AA sequence:RefSeq:WP_011587802.1
GO:0004045 - aminoacyl-tRNA hydrolase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011587803.1
GO:0008097 - 5S rRNA binding [Evidence IEA]; GO:0003735 - structural constituent of ribosome [Evidence IEA]
50S ribosomal protein L25/general stress protein Ctc
ATP + D-ribose 5-phosphate = AMP + 5-phospho-alpha-D-ribose 1-diphosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_007149324.1
catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2c-methyl-d-erythritol (by similarity). atp + 4-(cytidine 5'-diphospho)-2-c-methyl-d- erythritol = adp + 2-phospho-4-(cytidine 5'-diphospho)-2-c-methyl- d-erythritol.
COORDINATES: similar to AA sequence:RefSeq:WP_011587805.1
GO:0050515 - 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity [Evidence IEA]
GO:0016114 - terpenoid biosynthetic process [Evidence IEA]
4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase
COORDINATES: similar to AA sequence:RefSeq:WP_007150623.1
GO:0008320 - protein transmembrane transporter activity [Evidence IEA]
lipoprotein insertase outer membrane protein LolB
COORDINATES: similar to AA sequence:RefSeq:WP_007149861.1
glutamyl-trna(glu) + nadph = glutamate-1-semialdehyde + nadp(+) + trna(glu)
COORDINATES: similar to AA sequence:RefSeq:WP_011587808.1
GO:0008883 - glutamyl-tRNA reductase activity [Evidence IEA]
peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons uag and uaa
COORDINATES: similar to AA sequence:RefSeq:WP_011587809.1
COORDINATES: similar to AA sequence:RefSeq:WP_014995950.1
GO:0008757 - S-adenosylmethionine-dependent methyltransferase activity [Evidence IEA]
GO:0018364 - peptidyl-glutamine methylation [Evidence IEA]; GO:0006412 - translation [Evidence IEA]
peptide chain release factor N(5)-glutamine methyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_008929188.1
GO:0008641 - ubiquitin-like modifier activating enzyme activity [Evidence IEA]
molybdopterin-synthase adenylyltransferase MoeB
COORDINATES: similar to AA sequence:RefSeq:WP_011587812.1
Assembled with A and C subunitd =ATP + l-glutamyl-tRNA(gln) + l-glutamine = ADP + phosphate + l-glutaminyl-tRNA(gln) + l-glutamate
COORDINATES: similar to AA sequence:RefSeq:WP_011587813.1
GO:0016884 - carbon-nitrogen ligase activity, with glutamine as amido-N-donor [Evidence IEA]
Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB
Assembled with B and C subunits = ATP + l-glutamyl-tRNA(gln) + l-glutamine = ADP + phosphate + l-glutaminyl-tRNA(gln) + l-glutamate
COORDINATES: similar to AA sequence:RefSeq:WP_011587814.1
GO:0030956 - glutamyl-tRNA(Gln) amidotransferase complex [Evidence IEA]
GO:0050567 - glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity [Evidence IEA]
GO:0006424 - glutamyl-tRNA aminoacylation [Evidence IEA]
Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA
Assembled with A and B subunits =ATP + l-glutamyl-tRNA(gln) + l-glutamine = ADP + phosphate + l-glutaminyl-tRNA(gln) + l-glutamate
COORDINATES: similar to AA sequence:RefSeq:WP_007150089.1
Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC
involved in formation of the rod shape of the cell. may act as a negative regulator of ftsi
COORDINATES: similar to AA sequence:RefSeq:WP_011587816.1
involved in formation of the rod shape of the cell. may also contribute to regulation of formation of penicillin-binding proteins
COORDINATES: similar to AA sequence:RefSeq:WP_007150294.1
GO:0008360 - regulation of cell shape [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150669.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587819.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929199.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151281.1
carbon-nitrogen hydrolase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_007149760.1
GO:0008237 - metallopeptidase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011587823.1
cyclic nucleotide-binding domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_007149653.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150158.1
possible gene required for the production of an antibiotic peptide
COORDINATES: similar to AA sequence:RefSeq:WP_007150663.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148384.1
GO:0015095 - magnesium ion transmembrane transporter activity [Evidence IEA]
GO:0015693 - magnesium ion transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008958045.1
this is a second nitrate reductase enzyme which can substitute for the nra enzyme and allows e.coli to use nitrate as an electron acceptor during anaerobic growth. the gamma chain is a membrane-embedded heme-iron unit resembling cytochrome b, which transfers electrons from quinones to the beta subunit. nitrite + acceptor = nitrate + reduced acceptor.
COORDINATES: similar to AA sequence:RefSeq:WP_009286656.1
GO:0009325 - nitrate reductase complex [Evidence IEA]
GO:0008940 - nitrate reductase activity [Evidence IEA]
GO:0019645 - anaerobic electron transport chain [Evidence IEA]
respiratory nitrate reductase subunit gamma
COORDINATES: similar to AA sequence:RefSeq:WP_008958047.1
GO:0051131 - chaperone-mediated protein complex assembly [Evidence IEA]
nitrate reductase molybdenum cofactor assembly chaperone
this is a second nitrate reductase enzyme which can substitute for the nra enzyme and allows e.coli to use nitrate as an electron acceptor during anaerobic growth. the beta chain is an electron transfer unit containing four cysteine clusters involved in the formation of iron-sulfur centres. electrons are transferred from the gamma chain to the molybdenum cofactor of the alpha subunit. nitrite + acceptor = nitrate + reduced acceptor.
COORDINATES: similar to AA sequence:RefSeq:WP_014995394.1
GO:0009061 - anaerobic respiration [Evidence IEA]
second nitrate reductase enzyme which can substitute for the nra enzyme and could allow to use nitrate as an electron acceptor during anaerobic growth
COORDINATES: similar to AA sequence:RefSeq:WP_014995393.1
COORDINATES: similar to AA sequence:RefSeq:WP_014995392.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150503.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587835.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151552.1
GO:0008982 - protein-N(PI)-phosphohistidine-sugar phosphotransferase activity [Evidence IEA]
GO:0009401 - phosphoenolpyruvate-dependent sugar phosphotransferase system [Evidence IEA]; GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]
PTS IIA-like nitrogen regulatory protein PtsN
COORDINATES: similar to AA sequence:RefSeq:WP_011587837.1
GO:0022626 - cytosolic ribosome [Evidence IEA]; GO:0005840 - ribosome [Evidence IEA]
GO:0045182 - translation regulator activity [Evidence IEA]
GO:0009386 - translational attenuation [Evidence IEA]
ribosome-associated translation inhibitor RaiA
COORDINATES: similar to AA sequence:RefSeq:WP_007150048.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0001216 - DNA-binding transcription activator activity [Evidence IEA]; GO:0016987 - sigma factor activity [Evidence IEA]
GO:0006352 - DNA-templated transcription initiation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007151483.1
GO:0043190 - ATP-binding cassette (ABC) transporter complex [Evidence IEA]; GO:0009898 - cytoplasmic side of plasma membrane [Evidence IEA]
GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; GO:0015221 - lipopolysaccharide transmembrane transporter activity [Evidence IEA]
LPS export ABC transporter ATP-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_007148369.1
GO:0043190 - ATP-binding cassette (ABC) transporter complex [Evidence IEA]; GO:0030288 - outer membrane-bounded periplasmic space [Evidence IEA]
GO:0001530 - lipopolysaccharide binding [Evidence IEA]
lipopolysaccharide transport periplasmic protein LptA
COORDINATES: similar to AA sequence:RefSeq:WP_007149333.1
LPS export ABC transporter periplasmic protein LptC
COORDINATES: similar to AA sequence:RefSeq:WP_008929216.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149484.1
GO:0016853 - isomerase activity [Evidence IEA]
KpsF/GutQ family sugar-phosphate isomerase
COORDINATES: similar to AA sequence:RefSeq:WP_007148902.1
ABC transporter substrate-binding protein
probably a part of toluene transporter system
COORDINATES: similar to AA sequence:RefSeq:WP_007151304.1
BolA/IbaG family iron-sulfur metabolism protein
cell wall formation. adds enolpyruvyl to udp-n-acetylglucosamine (phosphoenolpyruvate + udp-n-acetyl-d-glucosamine = phosphate + udp-n-acetyl-3-o-(1-carboxyvinyl)-d- glucosamine)
COORDINATES: similar to AA sequence:RefSeq:WP_011587846.1
GO:0008760 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity [Evidence IEA]
GO:0009252 - peptidoglycan biosynthetic process [Evidence IEA]
UDP-N-acetylglucosamine 1-carboxyvinyltransferase
1-(5-phospho-D-ribosyl)-ATP + diphosphate = ATP + 5-phospho-alpha-D-ribose-1-diphosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_011587847.1
GO:0003879 - ATP phosphoribosyltransferase activity [Evidence IEA]
GO:0000105 - histidine biosynthetic process [Evidence IEA]
catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. L-histidinol + 2 NAD(+) + H(2)O = L-histidine + 2 NADH.
COORDINATES: similar to AA sequence:RefSeq:WP_007149992.1
GO:0004399 - histidinol dehydrogenase activity [Evidence IEA]
Histidinol-phosphate aminotransferase is a pyridoxal 5'-phosphate (PLP)-dependent enzyme catalyzing a reversible transamination reaction between histidinol phosphate and 2-oxoglutarate to form imidazole acetol phosphate and glutamate. L-histidinol-phosphate + 2-oxoglutarate = 3- (imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate.
COORDINATES: similar to AA sequence:RefSeq:WP_007151343.1
GO:0004400 - histidinol-phosphate transaminase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149833.1
COORDINATES: similar to AA sequence:RefSeq:WP_008738278.1
trypsin-like peptidase domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_008929225.1
GO:0051540 - metal cluster binding [Evidence IEA]
Nif3-like dinuclear metal center hexameric protein
COORDINATES: similar to AA sequence:RefSeq:WP_007149715.1
diacylglycerol kinase family lipid kinase
COORDINATES: similar to AA sequence:RefSeq:WP_014995886.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148620.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587856.1
GO:0051301 - cell division [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008929231.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929232.1
COORDINATES: protein motif:HMM:NF024863.2
COORDINATES: similar to AA sequence:RefSeq:WP_018918351.1
frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
This protein is one of the early assembly proteins of the 50S ribosomal subunit.
COORDINATES: similar to AA sequence:RefSeq:WP_005007737.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149663.1
component of the ubiquinol-cytochrome c reductase complex (complex iii or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. qh(2) + 2 ferricytochrome c = q + 2 ferrocytochrome c.
COORDINATES: similar to AA sequence:RefSeq:WP_007149851.1
GO:0045275 - respiratory chain complex III [Evidence IEA]
GO:0009055 - electron transfer activity [Evidence IEA]; GO:0008121 - ubiquinol-cytochrome-c reductase activity [Evidence IEA]
GO:0009060 - aerobic respiration [Evidence IEA]
ubiquinol-cytochrome c reductase iron-sulfur subunit
COORDINATES: similar to AA sequence:RefSeq:WP_008739495.1
cytochrome bc complex cytochrome b subunit
component of the ubiquinol-cytochrome c reductase complex (complex iii or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to atp synthesis. c1 functions as an electron donor to cytochrome c.
COORDINATES: similar to AA sequence:RefSeq:WP_007149895.1
forms an equimolar complex with the rna polymerase holoenzyme (rnap) but not with the core enzyme, it is synthesized predominantly when cells are exposed to amino acid starvation, at which time it accounts for over 5046f the total protein synthesized. it is involved in the transition from p1 early to p1 late gene expression. rnk and sspa can functionally replace p.aeruginosa alginate regulatory gene algr2.
COORDINATES: similar to AA sequence:RefSeq:WP_011587867.1
GO:0006749 - glutathione metabolic process [Evidence IEA]
Binding of SspB enhances degradation of tagged proteins by ClpX, and masks sequence elements important for ClpA interactions, inhibiting degradation by ClpA [1]. However, more recent work has cast doubt on the importance of SspB in wild-type cells [2]. SspB is encoded in an operon whose synthesis is stimulated by carbon, amino acid, and phosphate starvation. SspB may play a special role during nutrient stress, for example by ensuring rapid degradation of the products of stalled translation, without causing a global increase in degradation of all ClpXP substrates
stringent starvation protein B (SspB), is thought to enhance the specificity of degradation of tmRNA-tagged proteins by the ClpXP protease. The tmRNA tag, also known as ssrA, is an 11-aa peptide added to the C terminus of proteins stalled during translation, targets proteins for degradation by ClpXP and ClpAP. SspB a cytoplasmic protein that specifically binds to residues 1-4 and 7 of the tag.
COORDINATES: similar to AA sequence:RefSeq:WP_007148786.1
ClpXP protease specificity-enhancing factor
COORDINATES: similar to AA sequence:RefSeq:WP_014995831.1
involved in synthesis of glyceromannoheptose 7-phosphate (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_008929131.1
GO:0097367 - carbohydrate derivative binding [Evidence IEA]; GO:0008968 - D-sedoheptulose 7-phosphate isomerase activity [Evidence IEA]
GO:1901135 - carbohydrate derivative metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149337.1
GO:0004518 - nuclease activity [Evidence IEA]; GO:0003676 - nucleic acid binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150929.1
This family uses S-AdoMet in the methylation of diverse substrates
COORDINATES: similar to AA sequence:RefSeq:WP_008929128.1
GO:0008649 - rRNA methyltransferase activity [Evidence IEA]; GO:0008757 - S-adenosylmethionine-dependent methyltransferase activity [Evidence IEA]
GO:0000451 - rRNA 2'-O-methylation [Evidence IEA]
16S rRNA (cytidine(1402)-2'-O)-methyltransferase
COORDINATES: nucleotide motif:Rfam:14.4:RF00010
COORDINATES: similar to AA sequence:RefSeq:WP_014995826.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587875.1
GO:0043565 - sequence-specific DNA binding [Evidence IEA]
GO:0051302 - regulation of cell division [Evidence IEA]
division/cell wall cluster transcriptional repressor MraZ
COORDINATES: similar to AA sequence:RefSeq:WP_007148528.1
GO:0016434 - rRNA (cytosine) methyltransferase activity [Evidence IEA]
16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH
COORDINATES: similar to AA sequence:RefSeq:WP_007149822.1
responsible for the final stages of peptidoglycan biosynthesis for cell wall formation
COORDINATES: similar to AA sequence:RefSeq:WP_007149954.1
GO:0008658 - penicillin binding [Evidence IEA]
penicillin-binding transpeptidase domain-containing protein
UDP-N-acetylmuramyl tripeptide syntethase
COORDINATES: similar to AA sequence:RefSeq:WP_011587879.1
GO:0016881 - acid-amino acid ligase activity [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA]
GO:0009058 - biosynthetic process [Evidence IEA]; GO:0051301 - cell division [Evidence IEA]; GO:0008360 - regulation of cell shape [Evidence IEA]
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase
COORDINATES: similar to AA sequence:RefSeq:WP_007150377.1
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase
UDP-MurNAc-pentapeptide phosphotransferase
COORDINATES: similar to AA sequence:RefSeq:WP_008929121.1
GO:0008963 - phospho-N-acetylmuramoyl-pentapeptide-transferase activity [Evidence IEA]
phospho-N-acetylmuramoyl-pentapeptide- transferase
COORDINATES: similar to AA sequence:RefSeq:WP_011587882.1
GO:0008764 - UDP-N-acetylmuramoylalanine-D-glutamate ligase activity [Evidence IEA]
UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase
Bacterial cell division membrane protein
COORDINATES: similar to AA sequence:RefSeq:WP_011587883.1
GO:0051301 - cell division [Evidence IEA]; GO:0009252 - peptidoglycan biosynthetic process [Evidence IEA]
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase
COORDINATES: similar to AA sequence:RefSeq:WP_011587884.1
GO:0050511 - undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity [Evidence IEA]
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase
UDP-N-acetylmuramoyl-L-alanine synthetase
COORDINATES: similar to AA sequence:RefSeq:WP_011587885.1
GO:0008763 - UDP-N-acetylmuramate-L-alanine ligase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011587886.1
This protein may be involved in septum formation.
COORDINATES: similar to AA sequence:RefSeq:WP_011587887.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151175.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0005515 - protein binding [Evidence IEA]
GO:0043093 - FtsZ-dependent cytokinesis [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150913.1
GO:0003924 - GTPase activity [Evidence IEA]
involved in the biosynthesis of lipid a, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (udp-3-o-(3-hydroxytetradecanoyl)-n- acetylglucosamine + h(2)o = udp-3-o-(3-hydroxytetradecanoyl)- glucosamine + acetate)
COORDINATES: similar to AA sequence:RefSeq:WP_011587889.1
GO:0008759 - UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [Evidence IEA]
GO:0009245 - lipid A biosynthetic process [Evidence IEA]
UDP-3-O-acyl-N-acetylglucosamine deacetylase
COORDINATES: similar to AA sequence:RefSeq:WP_008929111.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587891.1
Involved in protein export. Interacts with the secY/secE subunits. SecA has a central role in coupling the hydrolysis of ATP to the transfer of pre-secretory periplasmic and outer membrane proteins across the membrane. Subunit: part of the prokaryotic protein translocation apparatus which comprise secA, secB, secD, secE, secF, secG and secY.
COORDINATES: similar to AA sequence:RefSeq:WP_011587892.1
GO:0006886 - intracellular protein transport [Evidence IEA]; GO:0017038 - protein import [Evidence IEA]; GO:0006605 - protein targeting [Evidence IEA]
catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetlyglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate. N(2)-acetyl-L-ornithine + L-glutamate = L-ornithine + N-acetyl-l-glutamate. acetyl-CoA + L-glutamate = CoA + N-acetyl-L- glutamate.
COORDINATES: similar to AA sequence:RefSeq:WP_007151248.1
GO:0004358 - glutamate N-acetyltransferase activity [Evidence IEA]
GO:0006526 - arginine biosynthetic process [Evidence IEA]
bifunctional glutamate N-acetyltransferase/amino-acid acetyltransferase ArgJ
NTP pyrophosphohydrolases including oxidative damage repair enzymes
COORDINATES: similar to AA sequence:RefSeq:WP_007149593.1
GO:0008413 - 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011587895.1
catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme a to form coenzyme a (atp + dephospho-coa = adp + coa)
COORDINATES: similar to AA sequence:RefSeq:WP_007150622.1
GO:0004140 - dephospho-CoA kinase activity [Evidence IEA]
Dephospho-CoA kinase (CoaE) performs the final step in coenzyme A biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
cleaves type-4 fimbrial leader sequence and methylates the n-terminal (generally phe) residue. processes the tapa pilin precursor during membrane translocation.
COORDINATES: similar to AA sequence:RefSeq:WP_008739563.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148843.1
involved in the translocation of the type iv pilin (pila)
COORDINATES: similar to AA sequence:RefSeq:WP_008929102.1
GO:0016887 - ATP hydrolysis activity [Evidence IEA]
GO:0009297 - pilus assembly [Evidence IEA]
COORDINATES: protein motif:HMM:NF012342.2
nicotinate d-ribonucleotide + diphosphate + co(2) = pyridine-2,3-dicarboxylate + 5-phospho-alpha-d-ribose 1- diphosphate
COORDINATES: similar to AA sequence:RefSeq:WP_008929100.1
GO:0004514 - nicotinate-nucleotide diphosphorylase (carboxylating) activity [Evidence IEA]
GO:0019363 - pyridine nucleotide biosynthetic process [Evidence IEA]
carboxylating nicotinate-nucleotide diphosphorylase
protein responsible for alanine transport. uses sodium cations as coupling cations for cotransport.
COORDINATES: similar to AA sequence:RefSeq:WP_008929099.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149122.1
participates in the intracellular recycling of peptidoglycan fragments
COORDINATES: similar to AA sequence:RefSeq:WP_008929097.1
GO:0008745 - N-acetylmuramoyl-L-alanine amidase activity [Evidence IEA]
GO:0009253 - peptidoglycan catabolic process [Evidence IEA]
1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD
COORDINATES: similar to AA sequence:RefSeq:WP_007149224.1
the pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-coa & co(2). it contains multiple copies of three enzymatic components: pyruvate dehydrogenase (e1), dihydrolipoamide acetyltransferase (e2) & lipoamide dehydrogenase (e3) (by similarity). pyruvate + lipoamide = s-acetyldihydrolipoamide + co(2).
COORDINATES: similar to AA sequence:RefSeq:WP_007151204.1
GO:0045250 - cytosolic pyruvate dehydrogenase complex [Evidence IEA]
GO:0004738 - pyruvate dehydrogenase activity [Evidence IEA]
GO:0006086 - acetyl-CoA biosynthetic process from pyruvate [Evidence IEA]
pyruvate dehydrogenase (acetyl-transferring), homodimeric type
the pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-coa and co(2). it contains multiple copies of three enzymatic components: pyruvate dehydrogenase (e1), dihydrolipoamide acetyltransferase (e2) and lipoamide dehydrogenase (e3). acetyl-coa + dihydrolipoamide = coa + s-acetyldihydrolipoamide.
COORDINATES: similar to AA sequence:RefSeq:WP_008929093.1
GO:0045254 - pyruvate dehydrogenase complex [Evidence IEA]
GO:0004742 - dihydrolipoyllysine-residue acetyltransferase activity [Evidence IEA]
dihydrolipoyllysine-residue acetyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_007151449.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150966.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149549.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151585.1
GO:0008817 - corrinoid adenosyltransferase activity [Evidence IEA]
cob(I)yrinic acid a,c-diamide adenosyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_007150553.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149156.1
GO:0008677 - 2-dehydropantoate 2-reductase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150032.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151306.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587917.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587918.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587919.1
GO:0016887 - ATP hydrolysis activity [Evidence IEA]; GO:0005515 - protein binding [Evidence IEA]
60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_009095308.1
GO:0003964 - RNA-directed DNA polymerase activity [Evidence IEA]
GO:0000373 - Group II intron splicing [Evidence IEA]
group II intron reverse transcriptase/maturase
Uncharacterized membrane protein (homolog of Drosophila rhomboid)
COORDINATES: similar to AA sequence:RefSeq:WP_007149827.1
GO:0004252 - serine-type endopeptidase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008929078.1
catalyzes the condensation of the acetyl group of acetyl-coa with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate). Acetyl-CoA + 3-methyl-2-oxobutanoate + h(2)o = 2-hydroxy-2-isopropylsuccinate + CoA.
COORDINATES: similar to AA sequence:RefSeq:WP_015485512.1
GO:0003852 - 2-isopropylmalate synthase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007151170.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150494.1
GO:0008999 - peptide-alanine-alpha-N-acetyltransferase activity [Evidence IEA]
GO:0036211 - protein modification process [Evidence IEA]; GO:0042254 - ribosome biogenesis [Evidence IEA]
ribosomal protein S18-alanine N-acetyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_007148320.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149769.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929072.1
GO:0005525 - GTP binding [Evidence IEA]; GO:0003747 - translation release factor activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148307.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148785.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151018.1
COORDINATES: similar to AA sequence:RefSeq:WP_008737494.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149674.1
GO:0003985 - acetyl-CoA C-acetyltransferase activity [Evidence IEA]
GO:0006631 - fatty acid metabolic process [Evidence IEA]
destroys radicals which are normally produced within the cells and which are toxic to biological systems (2 superoxide + 2 h(+) = o(2) + h(2)o(2))
COORDINATES: similar to AA sequence:RefSeq:WP_007151159.1
SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_007150951.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930439.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149930.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149429.1
GO:0030745 - dimethylhistidine N-methyltransferase activity [Evidence IEA]
GO:0052699 - ergothioneine biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150902.1
3-hydroxyacyl-CoA + NAD(+) = 3-oxoacyl-CoA + NADH.
COORDINATES: similar to AA sequence:RefSeq:WP_011587941.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930433.1
nucleotide 5'-monophosphate nucleosidase PpnN
COORDINATES: similar to AA sequence:RefSeq:WP_007151335.1
Overexpression of polIV results in increased frameshift mutagenesis. It is required for stationary-phase adaptive mutation, which provides the bacterium with flexibility in dealing with environmental stress, enhancing long-term survival and evolutionary fitness. May be involved in translesional synthesis, in conjunction with the beta clamp from polIII. Catalytic activity: n deoxynucleoside triphosphate = n diphosphate + {dna}(n).
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3'-5' exonuclease (proofreading) activity.
COORDINATES: similar to AA sequence:RefSeq:WP_008930431.1
GO:0003684 - damaged DNA binding [Evidence IEA]; GO:0003887 - DNA-directed DNA polymerase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150780.1
specifically methylates the guanosine in position 745 of 23s rrna (s-adenosyl-l-methionine + rrna = s-adenosyl-l- homocysteine + rrna containing n(1)-methylguanine)
COORDINATES: similar to AA sequence:RefSeq:WP_011587946.1
methyltransferase domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_007020211.1
COORDINATES: similar to AA sequence:RefSeq:WP_020683996.1
COORDINATES: similar to AA sequence:RefSeq:WP_011786658.1
COORDINATES: similar to AA sequence:RefSeq:WP_076611494.1
frameshifted; internal stop; incomplete; partial in the middle of a contig; missing N-terminus and C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: protein motif:HMM:NF024039.2
COORDINATES: protein motif:HMM:NF015155.2
COORDINATES: similar to AA sequence:RefSeq:WP_011587952.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587953.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587954.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587955.1
ring-hydroxylating dioxygenase ferredoxin reductase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_011786653.1
GO:0051537 - 2 iron, 2 sulfur cluster binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011587957.1
COORDINATES: similar to AA sequence:RefSeq:WP_011786652.1
COORDINATES: similar to AA sequence:RefSeq:WP_011786651.1
COORDINATES: similar to AA sequence:RefSeq:WP_011786650.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148827.1
LLM class flavin-dependent oxidoreductase
COORDINATES: similar to AA sequence:RefSeq:WP_007148971.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151046.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150986.1
through the carboxylation of phosphoenolpyruvate (pep) it forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. phosphate + oxaloacetate = h(2)o + phosphoenolpyruvate + co(2).
COORDINATES: similar to AA sequence:RefSeq:WP_011587965.1
GO:0008964 - phosphoenolpyruvate carboxylase activity [Evidence IEA]
GO:0015977 - carbon fixation [Evidence IEA]; GO:0006099 - tricarboxylic acid cycle [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008929578.1
GO:0043231 - intracellular membrane-bounded organelle [Evidence IEA]
CDGSH iron-sulfur domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_007148543.1
GO:0008080 - N-acetyltransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150061.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929575.1
GO:0043043 - peptide biosynthetic process [Evidence IEA]; GO:0006414 - translational elongation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148640.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150573.1
rhomboid family intramembrane serine protease
COORDINATES: similar to AA sequence:RefSeq:WP_008929572.1
TRAP transporter TatT component family protein
catalyze uptake of dicarboxylates in a H(+)- or Na(+)-dicarboxylate symport
COORDINATES: similar to AA sequence:RefSeq:WP_007148727.1
TRAP transporter substrate-binding protein DctP
COORDINATES: similar to AA sequence:RefSeq:WP_007149913.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587975.1
GO:0005886 - plasma membrane [Evidence IEA]; GO:0031317 - tripartite ATP-independent periplasmic transporter complex [Evidence IEA]
GO:0015556 - C4-dicarboxylate transmembrane transporter activity [Evidence IEA]
GO:0015740 - C4-dicarboxylate transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148984.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149393.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150180.1
GO:0003994 - aconitate hydratase activity [Evidence IEA]
GO:0006099 - tricarboxylic acid cycle [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150165.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149292.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587982.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151137.1
COORDINATES: protein motif:HMM:NF017079.2
GO:0030288 - outer membrane-bounded periplasmic space [Evidence IEA]
GO:0071555 - cell wall organization [Evidence IEA]
GO:0015473 - fimbrial usher porin activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008929548.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929547.1
GO:0003824 - catalytic activity [Evidence IEA]; GO:0000287 - magnesium ion binding [Evidence IEA]; GO:0030976 - thiamine pyrophosphate binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149983.1
COORDINATES: similar to AA sequence:RefSeq:WP_011587991.1
COORDINATES: protein motif:HMM:NF023273.2
COORDINATES: similar to AA sequence:RefSeq:WP_009100619.1
GO:0051920 - peroxiredoxin activity [Evidence IEA]; GO:0008379 - thioredoxin peroxidase activity [Evidence IEA]
GO:0098869 - cellular oxidant detoxification [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_014995607.1
GO:0009263 - deoxyribonucleotide biosynthetic process [Evidence IEA]
ribonucleotide-diphosphate reductase subunit beta
catalyzes the reductive synthesis of deoxyribonucleotides
COORDINATES: similar to AA sequence:RefSeq:WP_007149902.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0004748 - ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [Evidence IEA]
ribonucleoside-diphosphate reductase subunit alpha
Response regulators consisting of a CheY
COORDINATES: similar to AA sequence:RefSeq:WP_008929542.1
functions as a membrane-associated protein kinase that phosphorylates rsta
COORDINATES: similar to AA sequence:RefSeq:WP_007149140.1
key enzyme in the regulation of glycerol uptake and metabolism. Catalytic activity: ATP + glycerol = ADP + glycerol 3-phosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_011587999.1
GO:0004370 - glycerol kinase activity [Evidence IEA]
GO:0006071 - glycerol metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149248.1
GO:0009975 - cyclase activity [Evidence IEA]
GO:0009966 - regulation of signal transduction [Evidence IEA]
sensor domain-containing diguanylate cyclase
COORDINATES: similar to AA sequence:RefSeq:WP_007151577.1
COORDINATES: similar to AA sequence:RefSeq:WP_008737936.1
catalyzes the conversion of ornithine and carbamoyl phosphate (CP) into citrulline and inorganic phosphate in the de novo pathway for arginine biosynthesis and in the detoxifying urea cycle. carbamoyl phosphate + L-ornithine = phosphate + L-citrulline.
COORDINATES: similar to AA sequence:RefSeq:WP_011588003.1
GO:0004585 - ornithine carbamoyltransferase activity [Evidence IEA]
GO:0042450 - arginine biosynthetic process via ornithine [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008929536.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929535.1
hydantoinase B/oxoprolinase family protein
binds and carries Fe (3+) into the periplasmic space (in the presence of tonB protein)
COORDINATES: similar to AA sequence:RefSeq:WP_014995596.1
COORDINATES: similar to AA sequence:RefSeq:WP_010325116.1
COORDINATES: similar to AA sequence:RefSeq:WP_014995594.1
COORDINATES: similar to AA sequence:RefSeq:WP_014995593.1
GO:0016896 - exoribonuclease activity, producing 5'-phosphomonoesters [Evidence IEA]
GO:0006364 - rRNA processing [Evidence IEA]; GO:0042780 - tRNA 3'-end processing [Evidence IEA]
ATP +L-citrulline +L-aspartate = AMP + diphosphate + L-argininosuccinate.
COORDINATES: similar to AA sequence:RefSeq:WP_011588009.1
GO:0004055 - argininosuccinate synthase activity [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA]
catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (R)-S-lactoylglutathione = glutathione + methylglyoxal.
COORDINATES: similar to AA sequence:RefSeq:WP_008929307.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150043.1
responsible for the addition of glutamic acid residues to the c-terminus of ribosomal protein s6
COORDINATES: similar to AA sequence:RefSeq:WP_007161257.1
30S ribosomal protein S6--L-glutamate ligase
COORDINATES: similar to AA sequence:RefSeq:WP_008929310.1
succinylglutamate desuccinylase/aspartoacylase family protein
forms adenosine 5'-phosphosulfate (APS) from ATP and free sulfate, the first step in the formation of the activated sulfate donor 3'-phosphoadenylylsulfate (PAPS)
COORDINATES: similar to AA sequence:RefSeq:WP_011588014.1
GO:0004781 - sulfate adenylyltransferase (ATP) activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149494.1
Catalysis of the reaction: peptide L-aspartate + 2-oxoglutarate + O2 = peptide 3-hydroxy-L-aspartate + succinate + CO2
COORDINATES: similar to AA sequence:RefSeq:WP_007149091.1
aspartyl/asparaginyl beta-hydroxylase domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_007149471.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149722.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0003676 - nucleic acid binding [Evidence IEA]
Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase.
COORDINATES: similar to AA sequence:RefSeq:WP_007151063.1
GO:0003678 - DNA helicase activity [Evidence IEA]
GO:0006310 - DNA recombination [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149145.1
GO:0015109 - chromate transmembrane transporter activity [Evidence IEA]
GO:0015703 - chromate transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011588021.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148600.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149306.1
GO:0002161 - aminoacyl-tRNA editing activity [Evidence IEA]; GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA]; GO:0000166 - nucleotide binding [Evidence IEA]; GO:0004827 - proline-tRNA ligase activity [Evidence IEA]
GO:0006433 - prolyl-tRNA aminoacylation [Evidence IEA]; GO:0006418 - tRNA aminoacylation for protein translation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149834.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151312.1
translocation/assembly module TamB domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_007148610.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148649.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151359.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150953.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149385.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151203.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588032.1
tp + l-aspartate + trna(asp) = amp + diphosphate + l-aspartyl-trna(asp).
COORDINATES: similar to AA sequence:RefSeq:WP_007150352.1
GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA]; GO:0016874 - ligase activity [Evidence IEA]; GO:0000166 - nucleotide binding [Evidence IEA]
GO:0006418 - tRNA aminoacylation for protein translation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011588034.1
YebC/PmpR family DNA-binding transcriptional regulator
nuclease that resolves Holliday junction intermediates in genetic recombination. cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'terminal phosphate and a 3'terminal hydroxyl group
COORDINATES: similar to AA sequence:RefSeq:WP_011588035.1
GO:0008821 - crossover junction endodeoxyribonuclease activity [Evidence IEA]
crossover junction endodeoxyribonuclease RuvC
COORDINATES: similar to AA sequence:RefSeq:WP_007150963.1
GO:0009379 - Holliday junction helicase complex [Evidence IEA]
GO:0005524 - ATP binding [Evidence IEA]; GO:0003677 - DNA binding [Evidence IEA]; GO:0009378 - four-way junction helicase activity [Evidence IEA]
Holliday junction branch migration protein RuvA
the ruva-ruvb complex in the presence of atp renatures cruciform structure in supercoiled dna with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. ruvab is an helicase that mediates the holliday junction migration by localized denaturation and reanneling
COORDINATES: similar to AA sequence:RefSeq:WP_007149719.1
Holliday junction branch migration DNA helicase RuvB
COORDINATES: similar to AA sequence:RefSeq:WP_011588038.1
GO:0047617 - acyl-CoA hydrolase activity [Evidence IEA]; GO:0005515 - protein binding [Evidence IEA]
tol-pal system-associated acyl-CoA thioesterase
involved in the tonb-independent uptake of proteins
COORDINATES: similar to AA sequence:RefSeq:WP_007149201.1
GO:0015078 - proton transmembrane transporter activity [Evidence IEA]
GO:1902600 - proton transmembrane transport [Evidence IEA]
involved in TonB-independent transport of various receptor bound substrates including colicins
COORDINATES: similar to AA sequence:RefSeq:WP_008929337.1
GO:0098567 - periplasmic side of plasma membrane [Evidence IEA]
GO:0061024 - membrane organization [Evidence IEA]; GO:1902600 - proton transmembrane transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148516.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929339.1
Tol-Pal system beta propeller repeat protein TolB
Outer membrane protein and related peptidoglycan
COORDINATES: similar to AA sequence:RefSeq:WP_008929340.1
peptidoglycan-associated lipoprotein Pal
COORDINATES: similar to AA sequence:RefSeq:WP_008929341.1
YbgF trimerization domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_008929342.1
GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; GO:1904047 - S-adenosyl-L-methionine binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008929343.1
GO:0008616 - queuosine biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148944.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149032.1
DUF523 and DUF1722 domain-containing protein
transcriptional activator of the csg genes required for production of the curli (agf).
COORDINATES: similar to AA sequence:RefSeq:WP_007148678.1
This enzyme catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand, upon exposure to ultraviolet radiation. Catalytic activity: cyclobutadipyrimidine (in DNA) = 2 pyrimidine residues (in DNA).
COORDINATES: similar to AA sequence:RefSeq:WP_007150446.1
Acts on primary amines, and usually also on secondary and tertiary amines
COORDINATES: similar to AA sequence:RefSeq:WP_007149524.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148437.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151075.1
cyclopropane-fatty-acyl-phospholipid synthase family protein
catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
COORDINATES: similar to AA sequence:RefSeq:WP_007149878.1
GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; GO:0008987 - quinolinate synthetase A activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148820.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150804.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148403.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148353.1
GO:0016209 - antioxidant activity [Evidence IEA]; GO:0016491 - oxidoreductase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150867.1
L-aspartate 4-semialdehyde + pyruvate = dihydrodipicolinate + 2 H(2)O.
COORDINATES: similar to AA sequence:RefSeq:WP_011588060.1
GO:0008840 - 4-hydroxy-tetrahydrodipicolinate synthase activity [Evidence IEA]
4-hydroxy-tetrahydrodipicolinate synthase
COORDINATES: similar to AA sequence:RefSeq:WP_011588061.1
outer membrane protein assembly factor BamC
catalyses the hydrolysis of beta-lactamase
COORDINATES: similar to AA sequence:RefSeq:WP_007149632.1
catalyzes the seventh step in the de novo purine biosynthetic pathway; the ATP-dependent conversion of 5'-phosphoribosyl-5-aminoimidazole-4-carboxylic acid and aspartic acid to phosphoribosylaminoimidazole-succinocarboxamide synthase
COORDINATES: similar to AA sequence:RefSeq:WP_008929360.1
GO:0004639 - phosphoribosylaminoimidazolesuccinocarboxamide synthase activity [Evidence IEA]
GO:0006164 - purine nucleotide biosynthetic process [Evidence IEA]
phosphoribosylaminoimidazolesuccinocarboxamide synthase
COORDINATES: similar to AA sequence:RefSeq:WP_011588064.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151412.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149940.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151455.1
degrade murein via cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine
COORDINATES: similar to AA sequence:RefSeq:WP_011588068.1
GO:0008933 - lytic transglycosylase activity [Evidence IEA]
GO:0000270 - peptidoglycan metabolic process [Evidence IEA]
membrane-bound lytic murein transglycosylase MltF
Phosphoribosylformylglycinamidine (FGAM) synthase
COORDINATES: similar to AA sequence:RefSeq:WP_007149020.1
GO:0004642 - phosphoribosylformylglycinamidine synthase activity [Evidence IEA]
phosphoribosylformylglycinamidine synthase
COORDINATES: similar to AA sequence:RefSeq:WP_007150171.1
COORDINATES: similar to AA sequence:RefSeq:WP_014993766.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927633.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927632.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151470.1
GO:0010945 - CoA pyrophosphatase activity [Evidence IEA]; GO:0000287 - magnesium ion binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149553.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151189.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148443.1
GO:0004622 - lysophospholipase activity [Evidence IEA]
GO:0006629 - lipid metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008927621.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149614.1
GO:0020037 - heme binding [Evidence IEA]
GO:0017004 - cytochrome complex assembly [Evidence IEA]
Necessary for efficient export of extra-cytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes.
COORDINATES: similar to AA sequence:RefSeq:WP_008927619.1
GO:0048501 - signal recognition particle, plasma membrane targeting [Evidence IEA]
GO:0003924 - GTPase activity [Evidence IEA]; GO:0005048 - signal sequence binding [Evidence IEA]
In addition to being a ribosomal protein, S16 also has a cation-dependent endonuclease activity.
COORDINATES: similar to AA sequence:RefSeq:WP_010945696.1
essential for efficient processing of 16s rrna. probably part of the 30s subunit prior to or during the final step in the processing of 16s free 30s ribosomal subunits. it could be some accessory protein needed for efficient assembly of the 30s subunit. it is needed in a step prior to rbfa during the maturation of 16s rrna. it has affinity for free ribosomal 30s subunits but not for 70s ribosomes (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_011588083.1
Essential for efficient processing of 16S rRNA; Essential for efficient processing of 16S rRNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
is one of several nucleases operating together with the tRNA-modifying enzymes before the formation of the mature tRNA. It catalyses the reaction:S-adenosyl-L-methionine + tRNA -> S-adenosyl-L-homocysteine + tRNA containingN1-methylguanine, methylating guanosine(G) to N1-methylguanine (1-methylguanosine (m1G)) at position 37 of tRNAs that read CUN (leucine), CCN(proline), and CGG (arginine) codons. The presence of m1G improves the cellular growth rate and the polypeptide steptime and also prevents the tRNA from shifting the reading frame
COORDINATES: similar to AA sequence:RefSeq:WP_011588084.1
GO:0009019 - tRNA (guanine-N1-)-methyltransferase activity [Evidence IEA]
tRNA (guanosine(37)-N1)-methyltransferase TrmD
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
COORDINATES: similar to AA sequence:RefSeq:WP_008927615.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148494.1
GlsB/YeaQ/YmgE family stress response membrane protein
COORDINATES: similar to AA sequence:RefSeq:WP_007151399.1
GO:0009009 - site-specific recombinase activity [Evidence IEA]
required for disulfide bond formation in some periplasmic proteins. also acts as a disulfide isomerase
COORDINATES: similar to AA sequence:RefSeq:WP_007148481.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927611.1
GO:0003824 - catalytic activity [Evidence IEA]; GO:0030170 - pyridoxal phosphate binding [Evidence IEA]
L-homoserine + NAD(P)(+) = L-aspartate 4-semialdehyde + NAD(P)H.
COORDINATES: similar to AA sequence:RefSeq:WP_007150774.1
O-phospho-L-homoserine + H(2)O = L-threonine + phosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_007150588.1
GO:0004795 - threonine synthase activity [Evidence IEA]
GO:0009088 - threonine biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148772.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149425.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588094.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149312.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148726.1
CaiB/BaiF CoA-transferase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_011588097.1
GO:0008173 - RNA methyltransferase activity [Evidence IEA]; GO:0009020 - tRNA (guanosine-2'-O-)-methyltransferase activity [Evidence IEA]
GO:0030488 - tRNA methylation [Evidence IEA]
tRNA (guanosine(18)-2'-O)-methyltransferase TrmH
COORDINATES: similar to AA sequence:RefSeq:WP_007151327.1
50S ribosomal protein L11 methyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_007150799.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148925.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150125.1
medium chain dehydrogenase/reductase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_013333635.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151631.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588104.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0000287 - magnesium ion binding [Evidence IEA]; GO:0004644 - phosphoribosylglycinamide formyltransferase activity [Evidence IEA]
formate-dependent phosphoribosylglycinamide formyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_012071663.1
GO:0008251 - tRNA-specific adenosine deaminase activity [Evidence IEA]; GO:0008270 - zinc ion binding [Evidence IEA]
GO:0002100 - tRNA wobble adenosine to inosine editing [Evidence IEA]
has porin activity, forming small water-filled channels. also has a structural role in determining cell shape and ability to grow in low-osmolarity medium (by similarity)
COORDINATES: similar to AA sequence:RefSeq:WP_011588106.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150492.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151065.1
GO:0016872 - intramolecular lyase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149684.1
nuclear transport factor 2 family protein
COORDINATES: similar to AA sequence:RefSeq:WP_007149750.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149313.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149214.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151100.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150305.1
COORDINATES: similar to AA sequence:RefSeq:WP_017902831.1
lator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcriptional regu
COORDINATES: similar to AA sequence:RefSeq:WP_011588116.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148725.1
catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-acp (acyl-[acyl-carrier protein] + malonyl-[acyl- carrier protein] = 3-oxoacyl-[acyl-carrier protein] + co(2) + [acyl-carrier protein])
COORDINATES: similar to AA sequence:RefSeq:WP_009097702.1
GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]
GO:0006633 - fatty acid biosynthetic process [Evidence IEA]
necessary for the introduction of cis unsaturation into fatty acids. catalyzed the dehydration of (3r)-3-hydroxydecanoyl- acp to e-(2)-decenoyl-acp and then its isomerization to z-(3)- decenoyl-acp (by similarity). (3r)-3-hydroxydecanoyl-[acyl-carrier protein] = 2,3-decenoyl-[acyl-carrier protein] or 3,4-decenoyl-[acyl- carrier protein] + H(2)O.
COORDINATES: similar to AA sequence:RefSeq:WP_011588119.1
GO:0019171 - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity [Evidence IEA]
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA
COORDINATES: similar to AA sequence:RefSeq:WP_007149991.1
involved in the biogenesis of c-type cytochromes as well as in disulfide bond formation in periplasmic c-type cytochromes
COORDINATES: similar to AA sequence:RefSeq:WP_008929417.1
GO:0015036 - disulfide oxidoreductase activity [Evidence IEA]
DsbE family thiol:disulfide interchange protein
COORDINATES: similar to AA sequence:RefSeq:WP_011588122.1
cytochrome c-type biogenesis protein CcmH
COORDINATES: similar to AA sequence:RefSeq:WP_011588123.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588124.1
GO:0004017 - adenylate kinase activity [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA]
GO:0006139 - nucleobase-containing compound metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_014993912.1
COORDINATES: protein motif:HMM:NF016230.2
may perform analogous functions in iron detoxification and storage to that of animal ferritins.
COORDINATES: similar to AA sequence:RefSeq:WP_007150778.1
GO:0008199 - ferric iron binding [Evidence IEA]; GO:0004322 - ferroxidase activity [Evidence IEA]
GO:0006880 - intracellular sequestering of iron ion [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150607.1
GO:0008948 - oxaloacetate decarboxylase activity [Evidence IEA]; GO:0015081 - sodium ion transmembrane transporter activity [Evidence IEA]
GO:0036376 - sodium ion export across plasma membrane [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007151338.1
sodium-extruding oxaloacetate decarboxylase subunit alpha
lyase and sodium transporter (by similarity). oxaloacetate = pyruvate + co(2).
COORDINATES: similar to AA sequence:RefSeq:WP_009722201.1
sodium ion-translocating decarboxylase subunit beta
COORDINATES: similar to AA sequence:RefSeq:WP_008929410.1
COORDINATES: protein motif:HMM:NF022607.2
COORDINATES: similar to AA sequence:RefSeq:WP_009286525.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149427.1
COORDINATES: similar to AA sequence:RefSeq:WP_020683465.1
CmpA/NrtA family ABC transporter substrate-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_011588136.1
probably part of a high-affinity binding-protein- dependent transport system for nitrate. probably responsible for energy coupling to the transport system
COORDINATES: similar to AA sequence:RefSeq:WP_007150047.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150931.1
ammonium hydroxide + 3 nad(p)(+) + h(2)o = nitrite + 3 nad(p)h
COORDINATES: protein motif:HMM:NF019604.2
COORDINATES: protein motif:HMM:NF025890.2
COORDINATES: similar to AA sequence:RefSeq:WP_020410038.1
COORDINATES: protein motif:HMM:NF012272.2
Response regulator with antiterminator output domain
COORDINATES: similar to AA sequence:RefSeq:WP_007151333.1
COORDINATES: similar to AA sequence:RefSeq:WP_014993922.1
metE catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation. 5-methyltetrahydropteroyltri-L-glutamate + L- homocysteine = tetrahydropteroyltri-L-glutamate + L-methionine.
COORDINATES: similar to AA sequence:RefSeq:WP_011588145.1
GO:0003871 - 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity [Evidence IEA]; GO:0008270 - zinc ion binding [Evidence IEA]
GO:0008652 - amino acid biosynthetic process [Evidence IEA]; GO:0009086 - methionine biosynthetic process [Evidence IEA]
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase
control of the last step in methionine biosynthesis; metr is a positive activator of the meta, mete and meth genes. metr is also a negative regulator of its own expression. binds homocysteine as an inducer
COORDINATES: similar to AA sequence:RefSeq:WP_008738996.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150399.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150175.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150070.1
carboxypeptidase-like regulatory domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_007149924.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149391.1
COORDINATES: similar to AA sequence:RefSeq:WP_008740227.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148652.1
Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.
COORDINATES: similar to AA sequence:RefSeq:WP_011588154.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0022857 - transmembrane transporter activity [Evidence IEA]
cytochrome c biogenesis heme-transporting ATPase CcmA
COORDINATES: similar to AA sequence:RefSeq:WP_007151004.1
GO:0015232 - heme transmembrane transporter activity [Evidence IEA]
GO:0015886 - heme transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148604.1
Required for the biogenesis of c-type cytochromes. possible subunit of a heme lyase (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_007148908.1
GO:0017004 - cytochrome complex assembly [Evidence IEA]; GO:0015886 - heme transport [Evidence IEA]
Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase.
COORDINATES: similar to AA sequence:RefSeq:WP_007021029.1
GO:0017004 - cytochrome complex assembly [Evidence IEA]; GO:0017003 - protein-heme linkage [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149327.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151352.1
catalyzes the isomerization of 2 and 3-phosphoglycerates, and are essential for glucose metabolism
COORDINATES: similar to AA sequence:RefSeq:WP_007148373.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150517.1
probably involved in the export of a complex carbohydrate like a cell-surface polysaccharide or aminoglycoside antibiotics
COORDINATES: similar to AA sequence:RefSeq:WP_007150736.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588164.1
GO:0043867 - 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity [Evidence IEA]; GO:0033739 - preQ1 synthase activity [Evidence IEA]
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
NADPH-dependent 7-cyano-7-deazaguanine reductase QueF
cryptic, but when expressed on a high copy number plasmid, or when expressed at higher levels due to mutation, it allows utilization of p-aminobenzoyl-glutamate as a source of p-aminobenzoate for p-aminobenzoate auxotrophs
COORDINATES: similar to AA sequence:RefSeq:WP_007149026.1
GO:0015558 - secondary active p-aminobenzoyl-glutamate transmembrane transporter activity [Evidence IEA]
GO:1902604 - p-aminobenzoyl-glutamate transmembrane transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149698.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928318.1
YiiD C-terminal domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_011588168.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151592.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151117.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150016.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150416.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149658.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148845.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150448.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150665.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148428.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149159.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151043.1
GO:0016757 - glycosyltransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150866.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927585.1
GO:0004866 - endopeptidase inhibitor activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008927584.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927583.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927582.1
involved in biosynthesis of an unidentified cell surface polysaccharide
COORDINATES: similar to AA sequence:RefSeq:WP_007149536.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148657.1
involved in the export of an unidentified cell surface polysaccharide
COORDINATES: similar to AA sequence:RefSeq:WP_007149474.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149667.1
Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
Involved in biosynthesis or export of an unidentified cell surface polysaccharide
COORDINATES: similar to AA sequence:RefSeq:WP_008735096.1
GO:0045226 - extracellular polysaccharide biosynthetic process [Evidence IEA]
polysaccharide biosynthesis tyrosine autokinase
COORDINATES: similar to AA sequence:RefSeq:WP_011588192.1
GO:0051287 - NAD binding [Evidence IEA]; GO:0016491 - oxidoreductase activity [Evidence IEA]
GO:0000271 - polysaccharide biosynthetic process [Evidence IEA]
Vi polysaccharide biosynthesis UDP-N-acetylglucosamine C-6 dehydrogenase TviB
COORDINATES: similar to AA sequence:RefSeq:WP_007148891.1
NAD-dependent epimerase/dehydratase family protein
dtdp-glucose = dtdp-4-dehydro-6-deoxy-d-glucose + h(2)o.
COORDINATES: similar to AA sequence:RefSeq:WP_011396286.1
GO:0008460 - dTDP-glucose 4,6-dehydratase activity [Evidence IEA]
GO:0019305 - dTDP-rhamnose biosynthetic process [Evidence IEA]; GO:0009243 - O antigen biosynthetic process [Evidence IEA]
dtdp-6-deoxy-l-mannose + nadp(+) = dtdp-4-dehydro-6-deoxy-l-mannose + nadph.
COORDINATES: similar to AA sequence:RefSeq:WP_017430743.1
COORDINATES: protein motif:HMM:NF013884.2
dttp + alpha-d-glucose 1-phosphate = diphosphate + dtdp-glucose.
COORDINATES: similar to AA sequence:RefSeq:WP_013332153.1
GO:0008879 - glucose-1-phosphate thymidylyltransferase activity [Evidence IEA]
glucose-1-phosphate thymidylyltransferase RfbA
dtdp-4-dehydro-6-deoxy-d-glucose = dtdp-4-dehydro-6-deoxy-l-mannose.
COORDINATES: similar to AA sequence:RefSeq:WP_019951084.1
GO:0008830 - dTDP-4-dehydrorhamnose 3,5-epimerase activity [Evidence IEA]
involved in the export of an unidentified cell surface polysaacharide
COORDINATES: protein motif:HMM:NF024832.2
COORDINATES: protein motif:HMM:NF015527.2
GO:0008146 - sulfotransferase activity [Evidence IEA]
sulfotransferase family 2 domain-containing protein
Glycosyltransferases involved in cell wall biogenesis
COORDINATES: protein motif:HMM:NF025025.2
COORDINATES: protein motif:HMM:NF024831.2
COORDINATES: protein motif:HMM:NF012744.2
COORDINATES: similar to AA sequence:RefSeq:WP_009286552.1
COORDINATES: similar to AA sequence:RefSeq:WP_009834102.1
involved in the biosynthesis of lipid a, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (by similarity)
COORDINATES: similar to AA sequence:RefSeq:WP_007150613.1
COORDINATES: similar to AA sequence:RefSeq:WP_014994076.1
DegT/DnrJ/EryC1/StrS aminotransferase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_007151611.1
nucleoside-diphosphate sugar epimerase/dehydratase
possibly involved in transmembrane transportation
COORDINATES: similar to AA sequence:RefSeq:WP_007151500.1
phosphorylation of adenylylsulphate (APS) to 3'-phosphoadenylylsulfate (PAPS)
COORDINATES: similar to AA sequence:RefSeq:WP_008930051.1
GO:0004020 - adenylylsulfate kinase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_009100578.1
provides UDPglucuronate, a precursor of cell surface polysaccharides
COORDINATES: similar to AA sequence:RefSeq:WP_008930050.1
GO:0051287 - NAD binding [Evidence IEA]; GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; GO:0003979 - UDP-glucose 6-dehydrogenase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008930049.1
may play a role in stationary phase survival.
COORDINATES: similar to AA sequence:RefSeq:WP_010628608.1
GO:0003983 - UTP:glucose-1-phosphate uridylyltransferase activity [Evidence IEA]
GO:0009225 - nucleotide-sugar metabolic process [Evidence IEA]
UTP--glucose-1-phosphate uridylyltransferase GalU
Provides a sugar nucleotide precursor involved in the biosynthesis of cell surface polysaccharides
COORDINATES: similar to AA sequence:RefSeq:WP_008930047.1
d-glucose 6-phosphate = d-fructose 6-phosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_011588220.1
GO:0004347 - glucose-6-phosphate isomerase activity [Evidence IEA]
GO:0006094 - gluconeogenesis [Evidence IEA]; GO:0006096 - glycolytic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008735152.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930044.1
GO:0003978 - UDP-glucose 4-epimerase activity [Evidence IEA]
GO:0006012 - galactose metabolic process [Evidence IEA]
possilby involved in export or polymerization of an unidentified polysaccharide
COORDINATES: protein motif:HMM:NF012888.2
COORDINATES: similar to AA sequence:RefSeq:WP_008930041.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930038.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0003677 - DNA binding [Evidence IEA]; GO:0003678 - DNA helicase activity [Evidence IEA]
GO:0032508 - DNA duplex unwinding [Evidence IEA]; GO:0006260 - DNA replication [Evidence IEA]
exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.
COORDINATES: similar to AA sequence:RefSeq:WP_011588228.1
Helicase subunit of the DNA excision repair complex
COORDINATES: similar to AA sequence:RefSeq:WP_007149582.1
GO:0009380 - excinuclease repair complex [Evidence IEA]
GO:0005524 - ATP binding [Evidence IEA]; GO:0016887 - ATP hydrolysis activity [Evidence IEA]; GO:0003677 - DNA binding [Evidence IEA]; GO:0016787 - hydrolase activity [Evidence IEA]; GO:0005515 - protein binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008739013.1
GO:0015116 - sulfate transmembrane transporter activity [Evidence IEA]
GO:0000103 - sulfate assimilation [Evidence IEA]
plays an important role in chromosome structure and partitioning. essential for chromosome partition.
COORDINATES: similar to AA sequence:RefSeq:WP_007151165.1
GO:0030261 - chromosome condensation [Evidence IEA]; GO:0007059 - chromosome segregation [Evidence IEA]
Interacts directly with the cell division protein ftsZ. Probable receptor for the septal ring structure, may anchor it to the inner-membrane (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_007150031.1
GO:0000917 - division septum assembly [Evidence IEA]
This protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. Catalytic activity: NAD(+) + {deoxyribonucleotide}(n) + {deoxyribonucleotide}(m) = AMP + nicotinamide nucleotide + {deoxyribonucleotide}(n+m).
COORDINATES: similar to AA sequence:RefSeq:WP_011588233.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0003911 - DNA ligase (NAD+) activity [Evidence IEA]
GO:0006281 - DNA repair [Evidence IEA]; GO:0006260 - DNA replication [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008928186.1
transglycosylase SLT domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_007148883.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588236.1
PhzF family phenazine biosynthesis protein
stereospecific condensation of phosphoenolpyruvate (pep) and D-erythrose-4-phosphate (e4p) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). phosphoenolpyruvate + D-erythrose-4-phosphate + H(2)O = 3-deoxy-D-erythro-hept-2-ulosonate 7-phosphate + phosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_007151609.1
GO:0003849 - 3-deoxy-7-phosphoheptulonate synthase activity [Evidence IEA]
GO:0009423 - chorismate biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011588238.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928331.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150389.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150816.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148448.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928337.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588244.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928339.1
oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor
COORDINATES: similar to AA sequence:RefSeq:WP_019621757.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588247.1
drug resistence, cation/drug antiporter (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_007151308.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148556.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149019.1
AbpA catalyses the NADPH reduction of ketopantoic acid to pantoic acid in the alternative pyrimidine biosynthetic (APB) pathway
COORDINATES: similar to AA sequence:RefSeq:WP_014994020.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148993.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148439.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149842.1
GO:0016645 - oxidoreductase activity, acting on the CH-NH group of donors [Evidence IEA]
FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC
COORDINATES: similar to AA sequence:RefSeq:WP_007149133.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151472.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149206.1
carboxy-S-adenosyl-L-methionine synthase CmoA
COORDINATES: similar to AA sequence:RefSeq:WP_007150741.1
tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB
COORDINATES: similar to AA sequence:RefSeq:WP_007150905.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149772.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151354.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928171.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151123.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151433.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928359.1
thiolytic cleavage of beta-ketoadipyl-coa to succinate and acetyl-coa
COORDINATES: similar to AA sequence:RefSeq:WP_009287810.1
catalyzes the oxidative decarboxylation of glutaryl-CoA
COORDINATES: similar to AA sequence:RefSeq:WP_007111527.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151559.1
catalyzes the formation of malonyl-CoA, the C2 donor for de novo synthesis of long-chain fatty acids
COORDINATES: similar to AA sequence:RefSeq:WP_014994144.1
acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha
COORDINATES: similar to AA sequence:RefSeq:WP_007150893.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588272.1
catalyzes the first step in the synthesis of long-chain fatty acids which involves the carboxylation of acetyl-CoA to malonyl-CoA
COORDINATES: similar to AA sequence:RefSeq:WP_007148433.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928164.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149288.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148482.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928161.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150770.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150435.1
synthesis of NADP which is essential for biosynthetic pathways
COORDINATES: similar to AA sequence:RefSeq:WP_011588279.1
GO:0003951 - NAD+ kinase activity [Evidence IEA]
GO:0006741 - NADP biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149160.1
COORDINATES: similar to AA sequence:RefSeq:WP_008735395.1
aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation. release of an N-terminal amino acid, xaa-|-xbb- from a peptide, amide or arylamide. xaa is preferably ala, but may be most amino acids including pro (slow action). when a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact xaa-pro dipeptide.
COORDINATES: similar to AA sequence:RefSeq:WP_008928155.1
GO:0004177 - aminopeptidase activity [Evidence IEA]; GO:0008237 - metallopeptidase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150927.1
COORDINATES: similar to AA sequence:RefSeq:WP_008735236.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150865.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148966.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148539.1
GO:0004152 - dihydroorotate dehydrogenase activity [Evidence IEA]
GO:0006222 - UMP biosynthetic process [Evidence IEA]
quinone-dependent dihydroorotate dehydrogenase
COORDINATES: similar to AA sequence:RefSeq:WP_035458491.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588289.1
GO:0003723 - RNA binding [Evidence IEA]; GO:0008990 - rRNA (guanine-N2-)-methyltransferase activity [Evidence IEA]
GO:0031167 - rRNA methylation [Evidence IEA]
bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL
COORDINATES: similar to AA sequence:RefSeq:WP_014994161.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928145.1
GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008928144.1
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Has been shown to bind to the 16 bp palindromic sequence 5'-ctgt-at(4)-acag-3'. In the presence of single-stranded DNA, recA interacts with lexA causing an autocatalytic cleavage which disrupts the DNA-binding part of lexA, leading to derepression of the SOS regulon and eventually DNA repair. Catalytic activity: hydrolysis of ala-|-gly bond in repressor lexA.
COORDINATES: similar to AA sequence:RefSeq:WP_011588293.1
GO:0006282 - regulation of DNA repair [Evidence IEA]; GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150848.1
Universal stress protein UspA and related nucleotide
COORDINATES: similar to AA sequence:RefSeq:WP_007149061.1
The reaction catalyzed by topoisomerases leads to the conversion of one topological isomer of DNA to another. Catalytic activity: ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.
COORDINATES: similar to AA sequence:RefSeq:WP_007149281.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0003917 - DNA topoisomerase type I (single strand cut, ATP-independent) activity [Evidence IEA]
GO:0006260 - DNA replication [Evidence IEA]; GO:0006265 - DNA topological change [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008928139.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150055.1
outer membrane lipoprotein-sorting protein
COORDINATES: similar to AA sequence:RefSeq:WP_007149709.1
COORDINATES: similar to AA sequence:RefSeq:WP_011507366.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150839.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150126.1
GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150993.1
mechanosensitive ion channel family protein
phosphoryl transfer reactions on activated form of ribose-5-phosphate
COORDINATES: similar to AA sequence:RefSeq:WP_011588304.1
hypoxanthine-guanine phosphoribosyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_014994175.1
Hemolysins and related proteins containing CBS domains
COORDINATES: similar to AA sequence:RefSeq:WP_011588306.1
O(3)-acetyl-L-serine + H(2)S = L-cysteine + acetate.
COORDINATES: similar to AA sequence:RefSeq:WP_007149098.1
GO:0004124 - cysteine synthase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149639.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928130.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148681.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150955.1
Transcription-repair coupling factor (superfamily II helicase)
COORDINATES: similar to AA sequence:RefSeq:WP_008928123.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0003684 - damaged DNA binding [Evidence IEA]; GO:0003676 - nucleic acid binding [Evidence IEA]
hydrolyzing saturated and unsaturated acyl-CoA substrates
COORDINATES: similar to AA sequence:RefSeq:WP_007149630.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151439.1
glycolysis and gluconeogenesis by reversibly catalysing the oxidation and phosphorylation of D-glyceraldehyde-3-phosphate to 1,3-diphospho- glycerate
COORDINATES: similar to AA sequence:RefSeq:WP_011588315.1
GO:0051287 - NAD binding [Evidence IEA]; GO:0050661 - NADP binding [Evidence IEA]; GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]
GO:0006006 - glucose metabolic process [Evidence IEA]
glyceraldehyde-3-phosphate dehydrogenase
nqr complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions,coupled with the transport of na(+) ions from the cytoplasm to the periplasm. nqra to nqre are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (by similarity). nadh + ubiquinone + na(+)(in) = nad(+) + ubiquinol + na(+)(out).
COORDINATES: similar to AA sequence:RefSeq:WP_011588316.1
GO:0016655 - oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [Evidence IEA]
Na(+)-translocating NADH-quinone reductase subunit A
COORDINATES: similar to AA sequence:RefSeq:WP_008928118.1
GO:0010181 - FMN binding [Evidence IEA]; GO:0016655 - oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [Evidence IEA]
GO:0022904 - respiratory electron transport chain [Evidence IEA]; GO:0055085 - transmembrane transport [Evidence IEA]
NADH:ubiquinone reductase (Na(+)-transporting) subunit B
COORDINATES: similar to AA sequence:RefSeq:WP_007149451.1
Na(+)-translocating NADH-quinone reductase subunit C
COORDINATES: similar to AA sequence:RefSeq:WP_007148629.1
NADH:ubiquinone reductase (Na(+)-transporting) subunit D
COORDINATES: similar to AA sequence:RefSeq:WP_011396546.1
NADH:ubiquinone reductase (Na(+)-transporting) subunit E
nqr complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions,coupled with the transport of na(+) ions from the cytoplasm to the periplasm. the first step is catalyzed by nqrf, which accepts electrons from nadh and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (by similarity). nadh + ubiquinone + na(+)(in) = nad(+) + ubiquinol + na(+)(out).
COORDINATES: similar to AA sequence:RefSeq:WP_011588321.1
NADH:ubiquinone reductase (Na(+)-transporting) subunit F
COORDINATES: similar to AA sequence:RefSeq:WP_007150716.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151334.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148621.1
GNAT family N-acetyltransferase/peptidase C39 family protein
COORDINATES: similar to AA sequence:RefSeq:WP_007149749.1
patatin-like phospholipase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_007148913.1
COORDINATES: similar to AA sequence:RefSeq:WP_014994198.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588328.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150300.1
polysaccharide deacetylase family protein
olase hydrolases that break carbon-nitrogen bonds
COORDINATES: similar to AA sequence:RefSeq:WP_008928105.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149349.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150501.1
COORDINATES: similar to AA sequence:RefSeq:WP_004900332.1
GO:0042953 - lipoprotein transport [Evidence IEA]
lipoprotein-releasing ABC transporter permease subunit
COORDINATES: similar to AA sequence:RefSeq:WP_007149563.1
GO:0043190 - ATP-binding cassette (ABC) transporter complex [Evidence IEA]
lipoprotein-releasing ABC transporter ATP-binding protein LolD
COORDINATES: similar to AA sequence:RefSeq:WP_008735351.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148515.1
GO:0009290 - DNA import into cell involved in transformation [Evidence IEA]
DNA internalization-related competence protein ComEC/Rec2
Involved in the tonB-dependent energy-dependent transport of unidentified receptor-bound substrates. protects exbd from proteolytic degradation and functionally stabilizes tonb (by similarity)
COORDINATES: similar to AA sequence:RefSeq:WP_008928098.1
MotA/TolQ/ExbB proton channel family protein
Involved in the tonB-dependent and energy-dependent transport of unidentified receptor-bound substrates
COORDINATES: similar to AA sequence:RefSeq:WP_007150916.1
Transfers the lipid A component of the lipopolysaccharides (LPS) to the outer face of the cell membrane
COORDINATES: similar to AA sequence:RefSeq:WP_011588339.1
GO:0005319 - lipid transporter activity [Evidence IEA]
GO:0006869 - lipid transport [Evidence IEA]
lipid A export permease/ATP-binding protein MsbA
Involved in the biosynthesis of the lipopolysaccharide component lipid A by transferring the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed ds-1- p) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVa) (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_011588340.1
GO:0009029 - tetraacyldisaccharide 4'-kinase activity [Evidence IEA]
Involved in the biosynthesis of the lipopolysaccharide (LPS) component lipid A by activating KDO (a required 8-carbon sugar) (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_011588341.1
GO:0008690 - 3-deoxy-manno-octulosonate cytidylyltransferase activity [Evidence IEA]
GO:0009244 - lipopolysaccharide core region biosynthetic process [Evidence IEA]
3-deoxy-manno-octulosonate cytidylyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_008928093.1
low molecular weight protein-tyrosine-phosphatase
cell wall formation (by similarity). Catalytic activity: udp-n-acetylmuramate + nadp(+) = udp-n- acetyl-3-o-(1-carboxyvinyl)-d-glucosamine + nadph.
COORDINATES: similar to AA sequence:RefSeq:WP_011588343.1
GO:0071949 - FAD binding [Evidence IEA]; GO:0008762 - UDP-N-acetylmuramate dehydrogenase activity [Evidence IEA]
matures 5s rrna from its precursors from all the rrna genes
COORDINATES: similar to AA sequence:RefSeq:WP_014995075.1
GO:0008995 - ribonuclease E activity [Evidence IEA]; GO:0003723 - RNA binding [Evidence IEA]
responsible for synthesis of pseudouridine from uracil at positions 955, 2504 and 2580 in 23s ribosomal rna (by similarity). Catalytic activity: uracil + d-ribose 5-phosphate = pseudouridine 5'-phosphate + h(2)o.
COORDINATES: similar to AA sequence:RefSeq:WP_007150845.1
GO:0009982 - pseudouridine synthase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148956.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150095.1
GO:0006465 - signal peptide processing [Evidence IEA]
Nucleotide-binding protein implicated in inhibition of septum formation
COORDINATES: similar to AA sequence:RefSeq:WP_011588348.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150431.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151009.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928082.1
GO:0043811 - phosphate:acyl-[acyl carrier protein] acyltransferase activity [Evidence IEA]
GO:0008610 - lipid biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011588352.1
GO:0004314 - [acyl-carrier-protein] S-malonyltransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008928080.1
GO:0004316 - 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [Evidence IEA]; GO:0051287 - NAD binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_014995065.1
COORDINATES: similar to AA sequence:RefSeq:WP_008956800.1
converts 4-amino-4-deoxychorismate into 4-aminobenzoate (paba) and pyruvate. Needs pyridoxal phosphate (by similarity) as cofactor.
COORDINATES: similar to AA sequence:RefSeq:WP_007150646.1
GO:0008696 - 4-amino-4-deoxychorismate lyase activity [Evidence IEA]
GO:0009396 - folic acid-containing compound biosynthetic process [Evidence IEA]; GO:0008153 - para-aminobenzoic acid biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011588356.1
GO:0008932 - lytic endotransglycosylase activity [Evidence IEA]
GO:0071555 - cell wall organization [Evidence IEA]; GO:0009252 - peptidoglycan biosynthetic process [Evidence IEA]
catalyzes the phosphorylation ofthymidine 5'-monophosphate (dTMP) to thymidine 5'-diphosphate (dTDP) in the presence of ATP and magnesium
COORDINATES: similar to AA sequence:RefSeq:WP_011588357.1
GO:0004798 - thymidylate kinase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011588358.1
GO:0008408 - 3'-5' exonuclease activity [Evidence IEA]; GO:0003677 - DNA binding [Evidence IEA]; GO:0003887 - DNA-directed DNA polymerase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008928073.1
GO:0035438 - cyclic-di-GMP binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148335.1
probably involved in dna recombination (by similarity)
COORDINATES: similar to AA sequence:RefSeq:WP_008928071.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928069.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928068.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149625.1
aminotransferase class V-fold PLP-dependent enzyme
COORDINATES: similar to AA sequence:RefSeq:WP_007149564.1
Uncharacterized protein conserved in bacteria
COORDINATES: similar to AA sequence:RefSeq:WP_007150268.1
protein amino acid phosphorylation and ATP binding
COORDINATES: similar to AA sequence:RefSeq:WP_007150977.1
GO:0004672 - protein kinase activity [Evidence IEA]
bifunctional protein-serine/threonine kinase/phosphatase
COORDINATES: similar to AA sequence:RefSeq:WP_008928063.1
GO:0015514 - nitrite efflux transmembrane transporter activity [Evidence IEA]
GO:0015707 - nitrite transport [Evidence IEA]
NarK family nitrate/nitrite MFS transporter
COORDINATES: similar to AA sequence:RefSeq:WP_011588369.1
GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; GO:0050661 - NADP binding [Evidence IEA]; GO:0008942 - nitrite reductase [NAD(P)H] activity [Evidence IEA]; GO:0016491 - oxidoreductase activity [Evidence IEA]
GO:0042128 - nitrate assimilation [Evidence IEA]
Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases
COORDINATES: similar to AA sequence:RefSeq:WP_007151458.1
GO:0051537 - 2 iron, 2 sulfur cluster binding [Evidence IEA]; GO:0008942 - nitrite reductase [NAD(P)H] activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148938.1
COORDINATES: similar to AA sequence:RefSeq:WP_011399532.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151376.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149174.1
stereospecific condensation of phosphoenolpyruvate (pep) and D-erythrose-4-phosphate (e4p) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP). phosphoenolpyruvate + D-erythrose-4-phosphate + H(2)O = 3-deoxy-D-erythro-hept-2-ulosonate 7-phosphate + phosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_007151566.1
NAD-dependent protein deacetylases, SIR2 family
COORDINATES: similar to AA sequence:RefSeq:WP_007022444.1
GO:0070403 - NAD+ binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150715.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149923.1
bifunctional GNAT family N-acetyltransferase/carbon-nitrogen hydrolase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_008930205.1
COORDINATES: similar to AA sequence:RefSeq:WP_015485698.1
COORDINATES: similar to AA sequence:RefSeq:WP_020683162.1
GO:0001522 - pseudouridine synthesis [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149636.1
accepts electrons from etf and reduces ubiquinone. reduced etf + ubiquinone = etf + ubiquinol.
COORDINATES: similar to AA sequence:RefSeq:WP_008928217.1
electron transfer flavoprotein-ubiquinone oxidoreductase
COORDINATES: similar to AA sequence:RefSeq:WP_014871356.1
electron transfer flavoprotein subunit beta/FixA family protein
COORDINATES: similar to AA sequence:RefSeq:WP_011588385.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150856.1
COORDINATES: protein motif:HMM:NF012801.2
COORDINATES: similar to AA sequence:RefSeq:WP_019952341.1
circularly permuted type 2 ATP-grasp protein
COORDINATES: similar to AA sequence:RefSeq:WP_008928223.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928224.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928225.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149457.1
GO:0008484 - sulfuric ester hydrolase activity [Evidence IEA]
hydrolyzes saturated and unsaturated acyl-CoA substrates
COORDINATES: similar to AA sequence:RefSeq:WP_007150412.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151221.1
1-acyl-sn-glycerol-3-phosphate acyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_007150784.1
binds medium- and long-chain acyl-CoA esterswith high affinity, and may act as an intra-cellular carrier of acyl-CoA esters
COORDINATES: similar to AA sequence:RefSeq:WP_008928230.1
GO:0000062 - fatty-acyl-CoA binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008735367.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151037.1
COORDINATES: similar to AA sequence:RefSeq:WP_014992791.1
Septum formation topological specificity factor
COORDINATES: similar to AA sequence:RefSeq:WP_011588401.1
GO:0032955 - regulation of division septum assembly [Evidence IEA]
cell division topological specificity factor MinE
COORDINATES: similar to AA sequence:RefSeq:WP_008928238.1
GO:0000918 - division septum site selection [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011588403.1
GO:0004857 - enzyme inhibitor activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148888.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588405.1
P-II indirectly controls the transcription of the glutamine synthetase gene (glnA). P-II prevents nr-ii catalyzed conversion of nr-i to nr-i-phosphate, the transcriptional activator of glnA. when P-II is uridylylated to P-II-UMP, these events are reversed. when the ratio of gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP, which causes the deadenylylation of glutamine synthetase by glnE, so activating the enzyme.
COORDINATES: similar to AA sequence:RefSeq:WP_016654695.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149892.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150082.1
links a guanosine 5'-phosphate to molydopterin (mpt) forming molybdopterin guanine dinucleotide (mgd) (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_008928247.1
NTP transferase domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_008928248.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588411.1
GO:0003725 - double-stranded RNA binding [Evidence IEA]
tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB
COORDINATES: similar to AA sequence:RefSeq:WP_008928250.1
confers resistance to bacitracin, probably by phosphorylation of undecaprenol.
COORDINATES: similar to AA sequence:RefSeq:WP_011588413.1
GO:0050380 - undecaprenyl-diphosphatase activity [Evidence IEA]
GO:0016311 - dephosphorylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150697.1
GO:0008990 - rRNA (guanine-N2-)-methyltransferase activity [Evidence IEA]
acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_007150989.1
GO:0004366 - glycerol-3-phosphate O-acyltransferase activity [Evidence IEA]
glycerol-3-phosphate 1-O-acyltransferase PlsB
COORDINATES: similar to AA sequence:RefSeq:WP_007148667.1
GO:0020037 - heme binding [Evidence IEA]; GO:0004601 - peroxidase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150917.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149594.1
COORDINATES: similar to AA sequence:RefSeq:WP_011507974.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151263.1
N-succinyl-LL-2,6-diaminoheptanedioate + H(2)O = succinate + LL-2,6-diaminoheptanedioate.
COORDINATES: similar to AA sequence:RefSeq:WP_011588420.1
GO:0009014 - succinyl-diaminopimelate desuccinylase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011588421.1
GO:0008666 - 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity [Evidence IEA]
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_007149906.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149254.1
GO:0009016 - succinyldiaminopimelate transaminase activity [Evidence IEA]
GO:0019877 - diaminopimelate biosynthetic process [Evidence IEA]
modifies, by uridylylation or deuridylylation the pii (glnb) regulatory protein (by similarity)
COORDINATES: similar to AA sequence:RefSeq:WP_011588424.1
GO:0008773 - [protein-PII] uridylyltransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008928265.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588426.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150241.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928268.1
GO:0033862 - UMP kinase activity [Evidence IEA]
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
COORDINATES: similar to AA sequence:RefSeq:WP_011588429.1
GO:0008135 - translation factor activity, RNA binding [Evidence IEA]
Catalyzes the sequential cis-condensation of isopentenyl diphosphate (IPP) onto (E,E)-farnesyl diphosphate (FPP).
COORDINATES: similar to AA sequence:RefSeq:WP_007149577.1
catalyzes the formation of CDP-diacylglycerol
COORDINATES: similar to AA sequence:RefSeq:WP_007151292.1
catalyzes the nadp-dependent rearrangement and reduction of 1-deoxy-d-xylulose-5-phosphate (dxp) to 2-c-methyl-d-erythritol 4-phosphate (mep) (by similarity). 2-c-methyl-d-erythritol 4-phosphate + nadp(+) = 1-deoxy-d-xylulose 5-phosphate + nadph.
COORDINATES: similar to AA sequence:RefSeq:WP_011588432.1
GO:0030604 - 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [Evidence IEA]; GO:0046872 - metal ion binding [Evidence IEA]; GO:0070402 - NADPH binding [Evidence IEA]; GO:0005515 - protein binding [Evidence IEA]
1-deoxy-D-xylulose-5-phosphate reductoisomerase
COORDINATES: similar to AA sequence:RefSeq:WP_007149163.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150474.1
outer membrane protein assembly factor BamA
COORDINATES: similar to AA sequence:RefSeq:WP_007148901.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588436.1
GO:0016410 - N-acyltransferase activity [Evidence IEA]
UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_007151339.1
GO:0016836 - hydro-lyase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008928278.1
GO:0008780 - acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [Evidence IEA]
acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase
involved in the biosynthesis of the lipopolysaccharide (LPS) component lipd A
COORDINATES: similar to AA sequence:RefSeq:WP_011588439.1
GO:0008915 - lipid-A-disaccharide synthase activity [Evidence IEA]
This enzyme is an endonuclease that degrades the RNA of RNA-DNA hybrids specifically. Catalytic activity: endonucleolytic cleavage to 5'-phosphomonoester.
COORDINATES: similar to AA sequence:RefSeq:WP_011588440.1
GO:0003723 - RNA binding [Evidence IEA]; GO:0004523 - RNA-DNA hybrid ribonuclease activity [Evidence IEA]
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase. Catalytic activity: n deoxynucleoside triphosphate = n diphosphate + {DNA}(n). subunit DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit.
This core dimerizes to form the polIII' complex. PolIII' associates with the gamma complex (composed of gamma,delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex. The final composition of the complex is: (alpha,epsilon,theta)[2]-tau[2]-(gamma,delta,delta', psi,chi)[2]-beta[4].
COORDINATES: similar to AA sequence:RefSeq:WP_007150149.1
GO:0008408 - 3'-5' exonuclease activity [Evidence IEA]; GO:0003676 - nucleic acid binding [Evidence IEA]
catalyzes carboxylation of acetyl-CoA to produce malonyl-CoA
COORDINATES: similar to AA sequence:RefSeq:WP_007148665.1
GO:0009317 - acetyl-CoA carboxylase complex [Evidence IEA]
GO:0003989 - acetyl-CoA carboxylase activity [Evidence IEA]
acetyl-CoA carboxylase carboxyltransferase subunit alpha
Predicted ATPase of the PP-loop superfamily implicated in cell cycle control
COORDINATES: similar to AA sequence:RefSeq:WP_007149998.1
GO:0016879 - ligase activity, forming carbon-nitrogen bonds [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149775.1
catalyzes reaction: L-glutamine + H2O + UTP + ATP = CTP + phosphate + ADP + L-glutamate
COORDINATES: similar to AA sequence:RefSeq:WP_011588445.1
GO:0003883 - CTP synthase activity [Evidence IEA]
GO:0006241 - CTP biosynthetic process [Evidence IEA]; GO:0006221 - pyrimidine nucleotide biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149276.1
GO:0008676 - 3-deoxy-8-phosphooctulonate synthase activity [Evidence IEA]
2-phospho-d-glycerate = phosphoenolpyruvate + H(2)O.
COORDINATES: similar to AA sequence:RefSeq:WP_007150504.1
GO:0004634 - phosphopyruvate hydratase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148986.1
septum formation initiator family protein
COORDINATES: similar to AA sequence:RefSeq:WP_007151431.1
GO:0050518 - 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity [Evidence IEA]
GO:0019288 - isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [Evidence IEA]
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
converts 4-diphosphocytidyl-2c-methyl-d-erythritol 2- phosphate into 2c-methyl-d-erythritol 2,4-cyclodiphosphate and cmp. also converts 4-diphosphocytidyl-2c-methyl-d-erythritol into 2c-methyl-d-erythritol 3,4-cyclophosphate and cmp (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_011588450.1
GO:0008685 - 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [Evidence IEA]
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
COORDINATES: similar to AA sequence:RefSeq:WP_007149350.1
catalyzes the methyl esterification of l-isoaspartyl residues in peptides and proteins (s-adenosyl-l-methionine + protein l-beta- aspartate = s-adenosyl-l-homocysteine + protein l-beta-aspartate methyl ester). it plays a role in the repair and/or degradation of damaged proteins (by similarity)
COORDINATES: similar to AA sequence:RefSeq:WP_011588452.1
GO:0004719 - protein-L-isoaspartate (D-aspartate) O-methyltransferase activity [Evidence IEA]
protein-L-isoaspartate(D-aspartate) O-methyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_007148937.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150525.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149275.1
GO:0015562 - efflux transmembrane transporter activity [Evidence IEA]; GO:0008324 - monoatomic cation transmembrane transporter activity [Evidence IEA]
GO:0006812 - monoatomic cation transport [Evidence IEA]
cation diffusion facilitator family transporter
COORDINATES: similar to AA sequence:RefSeq:WP_007150737.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151574.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148456.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928300.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149018.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928312.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928313.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588463.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149938.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149298.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150857.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588467.1
GO:0008725 - DNA-3-methyladenine glycosylase activity [Evidence IEA]
GO:0006284 - base-excision repair [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149747.1
GO:0033573 - high-affinity iron permease complex [Evidence IEA]; GO:0016020 - membrane [Evidence IEA]
GO:0005381 - iron ion transmembrane transporter activity [Evidence IEA]
GO:0034755 - iron ion transmembrane transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150402.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149933.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148579.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150013.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588473.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150545.1
COORDINATES: protein motif:HMM:NF013775.2
methylation of lysine residues in histones and other proteins (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_007148468.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149662.1
degrades short-lived regulatory and abnormal proteins in presence of atp. hydrolyzes two atps for each peptide bond cleaved in the protein substrate (by similarity)
COORDINATES: similar to AA sequence:RefSeq:WP_020583675.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0016887 - ATP hydrolysis activity [Evidence IEA]; GO:0004252 - serine-type endopeptidase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011588479.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151576.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148890.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149165.1
GO:0008664 - 2'-5'-RNA ligase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148653.1
YbhB/YbcL family Raf kinase inhibitor-like protein
COORDINATES: similar to AA sequence:RefSeq:WP_076611291.1
GO:0015074 - DNA integration [Evidence IEA]
integrase core domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_007149196.1
bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase
myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA during lipopolysaccharide core biosynthesis, by sequence similarity
COORDINATES: similar to AA sequence:RefSeq:WP_011588485.1
synthesis of 2-methylthio-cis-ribozeatin in tRNA
COORDINATES: similar to AA sequence:RefSeq:WP_007150653.1
Lipid A biosynthesis, catalyzes the hydrolysis of the pyrophosphate bond of udp-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid x) and ump (by similarity)
COORDINATES: similar to AA sequence:RefSeq:WP_007149707.1
GO:0016462 - pyrophosphatase activity [Evidence IEA]
cis-trans isomerization of proline imidic peptide bonds in oligopeptide
COORDINATES: similar to AA sequence:RefSeq:WP_007149790.1
GO:0000413 - protein peptidyl-prolyl isomerization [Evidence IEA]
accelerates folding of proteins: catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
COORDINATES: similar to AA sequence:RefSeq:WP_007151150.1
atp + l-glutamine + trna(gln) = amp + diphosphate + l-glutaminyl-trna(gln).
COORDINATES: similar to AA sequence:RefSeq:WP_007149365.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0004819 - glutamine-tRNA ligase activity [Evidence IEA]; GO:0000166 - nucleotide binding [Evidence IEA]
GO:0006425 - glutaminyl-tRNA aminoacylation [Evidence IEA]
glutamine--tRNA ligase/YqeY domain fusion protein
COORDINATES: similar to AA sequence:RefSeq:WP_041704932.1
bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD
COORDINATES: similar to AA sequence:RefSeq:WP_011588492.1
GO:0005854 - nascent polypeptide-associated complex [Evidence IEA]
GO:0003755 - peptidyl-prolyl cis-trans isomerase activity [Evidence IEA]; GO:0051082 - unfolded protein binding [Evidence IEA]
GO:0051083 - 'de novo' cotranslational protein folding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008928510.1
GO:0009368 - endopeptidase Clp complex [Evidence IEA]
GO:0004176 - ATP-dependent peptidase activity [Evidence IEA]; GO:0004252 - serine-type endopeptidase activity [Evidence IEA]
ATP-dependent Clp endopeptidase proteolytic subunit ClpP
atp-dependent specificity component of the clp protease. it directs the protease to specific substrates. can perform chaperone functions in the absence of clpp (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_011588494.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0016887 - ATP hydrolysis activity [Evidence IEA]; GO:0046983 - protein dimerization activity [Evidence IEA]; GO:0008270 - zinc ion binding [Evidence IEA]
ATP-dependent Clp protease ATP-binding subunit ClpX
ATP-dependent Lon protease, bacterial type
COORDINATES: similar to AA sequence:RefSeq:WP_007151474.1
GO:0016887 - ATP hydrolysis activity [Evidence IEA]; GO:0004176 - ATP-dependent peptidase activity [Evidence IEA]; GO:0043565 - sequence-specific DNA binding [Evidence IEA]; GO:0004252 - serine-type endopeptidase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_012700946.1
seems to be involved in the folding of outer membrane proteins
COORDINATES: similar to AA sequence:RefSeq:WP_008928514.1
SurA N-terminal domain-containing protein
acyl-[acyl-carrier protein] + nad(+) = trans-2,3-dehydroacyl-[acyl-carrier protein] + nadh.
COORDINATES: similar to AA sequence:RefSeq:WP_007150414.1
part of the binding-protein-dependent transport system for oligopeptides. probably responsible for energy coupling to the transport system.
COORDINATES: similar to AA sequence:RefSeq:WP_007150541.1
GO:0015833 - peptide transport [Evidence IEA]
dipeptide ABC transporter ATP-binding protein
part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane. also required for sporulation and competence.
COORDINATES: similar to AA sequence:RefSeq:WP_011588500.1
part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane
COORDINATES: similar to AA sequence:RefSeq:WP_011588501.1
microcin C ABC transporter permease YejB
COORDINATES: similar to AA sequence:RefSeq:WP_007150020.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150873.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928521.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150634.1
GO:0004416 - hydroxyacylglutathione hydrolase activity [Evidence IEA]
GO:0019243 - methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150104.1
This enzyme is an endonuclease that degrades the RNA of RNA-DNA hybrids specifically. In E.coli RNAse H participates in DNA replication; it helps to specify the origin of genomic replication by suppressing initiation at origins other than the locus oric; along with the 5'-3' exonuclease of pol1, it removes RNA primers from the Okazaki fragments of lagging strand synthesis.
COORDINATES: similar to AA sequence:RefSeq:WP_011588507.1
GO:0003676 - nucleic acid binding [Evidence IEA]; GO:0004523 - RNA-DNA hybrid ribonuclease activity [Evidence IEA]
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contains the editing function and is a proofreading 3'-5' exonuclease. Catalytic activity. n deoxynucleoside triphosphate = n diphosphate + {dna}(n). Subunit DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit.
This core dimerizes to form the polIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta',psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex. The final composition of the complex is: (alpha,epsilon,theta)[2]-tau[2]-(gamma,delta,delta', psi,chi)[2]- beta[4].
COORDINATES: similar to AA sequence:RefSeq:WP_007150630.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0003887 - DNA-directed DNA polymerase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011588509.1
GO:0015385 - sodium:proton antiporter activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149049.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151048.1
GO:0016787 - hydrolase activity [Evidence IEA]; GO:0000210 - NAD+ diphosphatase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150156.1
multicopy suppressor of the htra (degp) null phenotype. it is possibly a protease, not essential for bacterial viability.
COORDINATES: similar to AA sequence:RefSeq:WP_008928530.1
GO:0008233 - peptidase activity [Evidence IEA]
catalyzes the reversible oxidation ofethanol to acetaldehyde with the concomitant reduction of NAD.
COORDINATES: similar to AA sequence:RefSeq:WP_007148742.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930270.1
Catalyzes the reversible conversion of tartronate semialdehyde into hydroxypyruvate
COORDINATES: similar to AA sequence:RefSeq:WP_007150558.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149107.1
GO:0051087 - chaperone binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149535.1
COORDINATES: similar to AA sequence:RefSeq:WP_014994788.1
GO:0030729 - acetoacetate-CoA ligase activity [Evidence IEA]
GO:0019287 - isopentenyl diphosphate biosynthetic process, mevalonate pathway [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008737523.1
biotin carboxylase N-terminal domain-containing protein
catalyzes the reversible hydration of unsaturated enoyl-CoA substrates to the corresponding hydroxyacyl-CoA products
COORDINATES: similar to AA sequence:RefSeq:WP_007148950.1
enoyl-CoA hydratase/isomerase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_014420929.1
carboxyl transferase domain-containing protein
3-methylbutanoyl-CoA + acceptor = 3-methylbut-2-enoyl-CoA + reduced acceptor
COORDINATES: similar to AA sequence:RefSeq:WP_008930260.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149116.1
MerR family DNA-binding transcriptional regulator
COORDINATES: similar to AA sequence:RefSeq:WP_007151243.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150598.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148758.1
converts dimethylmenaquinone (dmk) to menaquinone (mk) (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_007151266.1
GO:0008428 - ribonuclease inhibitor activity [Evidence IEA]
GO:0051252 - regulation of RNA metabolic process [Evidence IEA]
The exact function of CBSdomains is unknown,however it isthought that they bind to some as yet unidentified small molecule (perhaps with an adenosyl moiety) and regulate the activity of attached enzymatic or other domains.
COORDINATES: similar to AA sequence:RefSeq:WP_008930254.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150587.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930393.1
GO:0016615 - malate dehydrogenase activity [Evidence IEA]
GO:0006108 - malate metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150177.1
GO:0045550 - geranylgeranyl reductase activity [Evidence IEA]
GO:0030494 - bacteriochlorophyll biosynthetic process [Evidence IEA]; GO:0015995 - chlorophyll biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007151398.1
catalyzes hydrolysis of several water-soluble esters to the corresponding free acid and alcohol.
COORDINATES: similar to AA sequence:RefSeq:WP_007151484.1
COORDINATES: similar to AA sequence:RefSeq:WP_014994776.1
involved in cyanide detoxification (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_007150203.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150209.1
GO:0055052 - ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [Evidence IEA]; GO:0009897 - external side of plasma membrane [Evidence IEA]; GO:0030288 - outer membrane-bounded periplasmic space [Evidence IEA]
GO:0015412 - ABC-type molybdate transporter activity [Evidence IEA]; GO:0030973 - molybdate ion binding [Evidence IEA]
GO:0015689 - molybdate ion transport [Evidence IEA]
molybdate ABC transporter substrate-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_007150925.1
GO:0055052 - ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [Evidence IEA]; GO:0005886 - plasma membrane [Evidence IEA]
GO:0015412 - ABC-type molybdate transporter activity [Evidence IEA]
molybdate ABC transporter permease subunit
COORDINATES: similar to AA sequence:RefSeq:WP_011588539.1
GO:0055052 - ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [Evidence IEA]; GO:0009898 - cytoplasmic side of plasma membrane [Evidence IEA]
GO:0015412 - ABC-type molybdate transporter activity [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA]
molybdenum ABC transporter ATP-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_007148762.1
GO:0008961 - phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity [Evidence IEA]
GO:0042158 - lipoprotein biosynthetic process [Evidence IEA]
prolipoprotein diacylglyceryl transferase
COORDINATES: similar to AA sequence:RefSeq:WP_011588541.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149381.1
GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150170.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930378.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930377.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588546.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148784.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150641.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588549.1
acetyl-coa + h(2)o + glyoxylate = s-malate + coa
COORDINATES: similar to AA sequence:RefSeq:WP_011588550.1
GO:0004474 - malate synthase activity [Evidence IEA]
GO:0006097 - glyoxylate cycle [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149294.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150704.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149616.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151381.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148699.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149211.1
GO:0004018 - N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity [Evidence IEA]
GO:0006188 - IMP biosynthetic process [Evidence IEA]; GO:0009152 - purine ribonucleotide biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011588557.1
high frequency lysogenization protein HflD
s-adenosyl-l-methionine + trna = s-adenosyl-l-homocysteine + trna containing 5-methylaminomethyl-2-thiouridylate.
COORDINATES: similar to AA sequence:RefSeq:WP_011588558.1
GO:0016783 - sulfurtransferase activity [Evidence IEA]; GO:0016740 - transferase activity [Evidence IEA]
responsible for removing an oxidatively damaged form of guanine (8-hydroxy- guanine or 7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with near equal efficiency, leading to A.T to G.C transversions. MutT specifically degrades 8-oxo-dGTP to the monophosphate, with the concomitant release of pyrophosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_011588559.1
together with moaA, is involved in the conversion of a guanosine derivative (gxp) into molybdopterin precursor z (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_011588560.1
GO:0006777 - Mo-molybdopterin cofactor biosynthetic process [Evidence IEA]
cyclic pyranopterin monophosphate synthase MoaC
COORDINATES: similar to AA sequence:RefSeq:WP_007149551.1
molybdopterin converting factor subunit 1
COORDINATES: similar to AA sequence:RefSeq:WP_007150005.1
molybdenum cofactor biosynthesis protein MoaE
conversion of uracil bases to pseudouridine, by sequence similarity
COORDINATES: similar to AA sequence:RefSeq:WP_008929751.1
catalyzes the oxidative decarboxylation of isocitrate into alpha-ketoglutarate
COORDINATES: similar to AA sequence:RefSeq:WP_007151637.1
GO:0004450 - isocitrate dehydrogenase (NADP+) activity [Evidence IEA]
catalyzes the oxidative decarboxylation of isocitrate into alpha -ketoglutarate
COORDINATES: similar to AA sequence:RefSeq:WP_011588565.1
GO:0004450 - isocitrate dehydrogenase (NADP+) activity [Evidence IEA]; GO:0000287 - magnesium ion binding [Evidence IEA]; GO:0051287 - NAD binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150688.1
GO:0003676 - nucleic acid binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008929748.1
atp-dependent specificity component of the clpp protease. it directs the protease to specific substrates
COORDINATES: similar to AA sequence:RefSeq:WP_007150939.1
GO:0004176 - ATP-dependent peptidase activity [Evidence IEA]
GO:0043335 - protein unfolding [Evidence IEA]; GO:0006508 - proteolysis [Evidence IEA]
ATP-dependent Clp protease ATP-binding subunit ClpA
COORDINATES: similar to AA sequence:RefSeq:WP_008938619.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588569.1
GO:0004057 - arginyltransferase activity [Evidence IEA]
GO:0016598 - protein arginylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011588570.1
GO:0008914 - leucyltransferase activity [Evidence IEA]
leucyl/phenylalanyl-tRNA--protein transferase
thioredoxin + nadp(+) = thioredoxin disulfide + nadph.
COORDINATES: similar to AA sequence:RefSeq:WP_007150681.1
GO:0004791 - thioredoxin-disulfide reductase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011588572.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588573.1
outer membrane lipoprotein chaperone LolA
COORDINATES: similar to AA sequence:RefSeq:WP_007149084.1
replication-associated recombination protein A
COORDINATES: similar to AA sequence:RefSeq:WP_014994342.1
atp + l-serine + trna(ser) = amp + diphosphate + l-seryl-trna(ser).
COORDINATES: similar to AA sequence:RefSeq:WP_011588576.1
GO:0004828 - serine-tRNA ligase activity [Evidence IEA]
GO:0006434 - seryl-tRNA aminoacylation [Evidence IEA]
2 s-adenosyl-L-methionine + uroporphyrin iii = 2 s-adenosyl-L-homocysteine + sirohydrochlorin
COORDINATES: similar to AA sequence:RefSeq:WP_007149808.1
GO:0051287 - NAD binding [Evidence IEA]; GO:0043115 - precorrin-2 dehydrogenase activity [Evidence IEA]; GO:0051266 - sirohydrochlorin ferrochelatase activity [Evidence IEA]; GO:0004851 - uroporphyrin-III C-methyltransferase activity [Evidence IEA]
GO:0019354 - siroheme biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150299.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929736.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929734.1
GO:0016783 - sulfurtransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_014994349.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151486.1
COORDINATES: similar to AA sequence:RefSeq:WP_008736191.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149430.1
COORDINATES: similar to AA sequence:RefSeq:WP_008737691.1
UvrY/SirA/GacA family response regulator transcription factor
the uvrabc repair system catalyzes the recognition and processing of dna lesions. uvrc both incises the 5' and 3' sides of the lesion. the n-terminal half is responsible for the 3' incision and the c-terminal half is responsible for the 5' incision
COORDINATES: similar to AA sequence:RefSeq:WP_011588587.1
GO:0009381 - excinuclease ABC activity [Evidence IEA]
catalyses the biosynthesis of phosphatidylglycerol
COORDINATES: similar to AA sequence:RefSeq:WP_011588588.1
GO:0008444 - CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity [Evidence IEA]
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_007150685.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151311.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149919.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149002.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149262.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150248.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588595.1
type II secretion system inner membrane protein GspF
COORDINATES: similar to AA sequence:RefSeq:WP_007149656.1
type II secretion system major pseudopilin GspG
COORDINATES: similar to AA sequence:RefSeq:WP_007148805.1
type II secretion system minor pseudopilin GspH
COORDINATES: similar to AA sequence:RefSeq:WP_007148932.1
type II secretion system minor pseudopilin GspI
COORDINATES: similar to AA sequence:RefSeq:WP_014994561.1
type II secretion system minor pseudopilin GspJ
COORDINATES: similar to AA sequence:RefSeq:WP_014994562.1
type II secretion system minor pseudopilin GspK
COORDINATES: similar to AA sequence:RefSeq:WP_007150935.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150511.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929710.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149953.1
GO:0016772 - transferase activity, transferring phosphorus-containing groups [Evidence IEA]
GO:0016310 - phosphorylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150116.1
5-methyltetrahydrofolate + L-homocysteine = tetrahydrofolate + L-methionine.
COORDINATES: similar to AA sequence:RefSeq:WP_008929708.1
GO:0008705 - methionine synthase activity [Evidence IEA]; GO:0008270 - zinc ion binding [Evidence IEA]
GO:0009086 - methionine biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148906.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929706.1
the transhydrogenation between nadh and nadp is coupled to respiration and atp hydrolysis and functions as a proton pump across the membrane (by similarity). nadph + nad(+) = nadp(+) + nadh.
COORDINATES: similar to AA sequence:RefSeq:WP_007151206.1
NAD(P)(+) transhydrogenase (Re/Si-specific) subunit beta
COORDINATES: similar to AA sequence:RefSeq:WP_014994608.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930537.1
GO:0008746 - NAD(P)+ transhydrogenase activity [Evidence IEA]
Re/Si-specific NAD(P)(+) transhydrogenase subunit alpha
COORDINATES: similar to AA sequence:RefSeq:WP_008930538.1
COORDINATES: similar to AA sequence:RefSeq:WP_014994611.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150227.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151274.1
nucleoside recognition domain-containing protein
COORDINATES: protein motif:HMM:NF024922.2
alpha-ketoglutarate-dependent dioxygenase AlkB
COORDINATES: similar to AA sequence:RefSeq:WP_008929236.1
GO:0015087 - cobalt ion transmembrane transporter activity [Evidence IEA]; GO:0015095 - magnesium ion transmembrane transporter activity [Evidence IEA]
GO:0006824 - cobalt ion transport [Evidence IEA]; GO:0015693 - magnesium ion transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008929237.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929238.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588620.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149397.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149746.1
COORDINATES: protein motif:HMM:NF008365.0
GO:0003677 - DNA binding [Evidence IEA]; GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]
fumarate/nitrate reduction transcriptional regulator Fnr
anaerobic transformation of coproporphyrinogen-iii into protoporphyrinogen-ix. Requires magnesium, ATP and NAD (or NADP) for activity.
COORDINATES: similar to AA sequence:RefSeq:WP_007150135.1
GO:0051989 - coproporphyrinogen dehydrogenase activity [Evidence IEA]
oxygen-independent coproporphyrinogen III oxidase
COORDINATES: protein motif:HMM:NF024778.2
sulfite exporter TauE/SafE family protein
COORDINATES: protein motif:HMM:TIGR00847.1
GO:0008535 - respiratory chain complex IV assembly [Evidence IEA]
cbb3-type cytochrome oxidase assembly protein CcoS
COORDINATES: similar to AA sequence:RefSeq:WP_007149192.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151070.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149552.1
cytochrome c oxidase accessory protein CcoG
high potential cytochrome c believed to be an intermediate electron donor to terminal oxidation systems
COORDINATES: similar to AA sequence:RefSeq:WP_007151364.1
GO:0004129 - cytochrome-c oxidase activity [Evidence IEA]
cytochrome-c oxidase, cbb3-type subunit III
COORDINATES: similar to AA sequence:RefSeq:WP_008739637.1
CcoQ/FixQ family Cbb3-type cytochrome c oxidase assembly chaperone
COORDINATES: similar to AA sequence:RefSeq:WP_014994629.1
cytochrome-c oxidase, cbb3-type subunit II
4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O
COORDINATES: similar to AA sequence:RefSeq:WP_007149792.1
cytochrome-c oxidase, cbb3-type subunit I
COORDINATES: similar to AA sequence:RefSeq:WP_007150696.1
zinc-dependent alcohol dehydrogenase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_007149268.1
COORDINATES: protein motif:HMM:NF012798.2
COORDINATES: protein motif:HMM:NF040041.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150465.1
COORDINATES: protein motif:HMM:NF027890.2
COORDINATES: similar to AA sequence:RefSeq:WP_011588640.1
GO:0015562 - efflux transmembrane transporter activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_001219642.1
incomplete; partial in the middle of a contig; missing N-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
Cd(II)/Pb(II)-responsive transcriptional regulator
COORDINATES: similar to AA sequence:RefSeq:WP_008958466.1
GO:0042625 - ATPase-coupled ion transmembrane transporter activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008930110.1
COORDINATES: similar to AA sequence:RefSeq:WP_020682345.1
mediates copper resistance by sequestration of copper in the periplasm along with the copper-binding protein copc. may have oxidase activity
COORDINATES: similar to AA sequence:RefSeq:WP_007150118.1
GO:0005507 - copper ion binding [Evidence IEA]; GO:0005375 - copper ion transmembrane transporter activity [Evidence IEA]
GO:0006825 - copper ion transport [Evidence IEA]
copper resistance system multicopper oxidase
COORDINATES: protein motif:HMM:NF012355.2
GO:0005507 - copper ion binding [Evidence IEA]; GO:0009055 - electron transfer activity [Evidence IEA]
plastocyanin/azurin family copper-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_007151491.1
COORDINATES: similar to AA sequence:RefSeq:WP_008740512.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; GO:0046872 - metal ion binding [Evidence IEA]
GO:0045893 - positive regulation of DNA-templated transcription [Evidence IEA]
involved in cation efflux across the cytoplasmic membrane.
COORDINATES: similar to AA sequence:RefSeq:WP_014702287.1
COORDINATES: similar to AA sequence:RefSeq:WP_013504665.1
COORDINATES: similar to AA sequence:RefSeq:WP_017045299.1
helix-turn-helix transcriptional regulator
AbrB/MazE/SpoVT family DNA-binding domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_011588654.1
COORDINATES: similar to AA sequence:RefSeq:WP_004588886.1
COORDINATES: similar to AA sequence:RefSeq:WP_014975577.1
COORDINATES: protein motif:HMM:NF040442.1
COORDINATES: similar to AA sequence:RefSeq:WP_019806281.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588664.1
CusA/CzcA family heavy metal efflux RND transporter
COORDINATES: similar to AA sequence:RefSeq:WP_011588659.1
COORDINATES: similar to AA sequence:RefSeq:WP_009575229.1
COORDINATES: similar to AA sequence:RefSeq:WP_003152688.1
COORDINATES: similar to AA sequence:RefSeq:WP_008735783.1
COORDINATES: similar to AA sequence:RefSeq:WP_008735781.1
COORDINATES: similar to AA sequence:RefSeq:WP_008985543.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588665.1
AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
COORDINATES: similar to AA sequence:RefSeq:WP_011588666.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151318.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588668.1
Predicted transcriptional regulator containing the HTH domain
COORDINATES: similar to AA sequence:RefSeq:WP_007148469.1
GO:0007059 - chromosome segregation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007151140.1
COORDINATES: similar to AA sequence:RefSeq:WP_014994666.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0000166 - nucleotide binding [Evidence IEA]; GO:0004830 - tryptophan-tRNA ligase activity [Evidence IEA]
GO:0006436 - tryptophanyl-tRNA aminoacylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149963.1
DNA-directed DNA polymerase. DNA replication.
COORDINATES: similar to AA sequence:RefSeq:WP_007148711.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149144.1
COORDINATES: similar to AA sequence:RefSeq:WP_016914815.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588676.1
TIGR04211 family SH3 domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_007151463.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929263.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148431.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150108.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150373.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929267.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149873.1
COORDINATES: similar to AA sequence:RefSeq:WP_014994680.1
sodium/hydrogen exchanger family protein
COORDINATES: similar to AA sequence:RefSeq:WP_007149284.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148943.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150291.1
COORDINATES: similar to AA sequence:RefSeq:WP_014994683.1
sn-glycerol 3-phosphate + acceptor = glycerone phosphate + reduced acceptor
COORDINATES: similar to AA sequence:RefSeq:WP_007150601.1
glycerol-3-phosphate dehydrogenase/oxidase
COORDINATES: similar to AA sequence:RefSeq:WP_008929275.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150830.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588692.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149041.1
GO:0006281 - DNA repair [Evidence IEA]; GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]
bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada
COORDINATES: similar to AA sequence:RefSeq:WP_007151238.1
COORDINATES: similar to AA sequence:RefSeq:WP_014994687.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149622.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929281.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148885.1
COORDINATES: protein motif:HMM:TIGR00369.1
COORDINATES: similar to AA sequence:RefSeq:WP_008735556.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149177.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929286.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151411.1
ATPases involved in chromosome partitioning
COORDINATES: similar to AA sequence:RefSeq:WP_010322341.1
maintain high levels of reduced glutathione in the cytosol
COORDINATES: similar to AA sequence:RefSeq:WP_007150789.1
GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; GO:0004362 - glutathione-disulfide reductase (NADPH) activity [Evidence IEA]; GO:0050661 - NADP binding [Evidence IEA]
GO:0045454 - cell redox homeostasis [Evidence IEA]; GO:0006749 - glutathione metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149748.1
FMN-binding glutamate synthase family protein
Bacterial lytic transglycosylases degrade murein via cleavage of the -1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine, with the concomitant formation of a 1,6-anhydrobond in the muramic acid residue.
COORDINATES: similar to AA sequence:RefSeq:WP_007148873.1
lytic transglycosylase domain-containing protein
Oxidoreductase and electron transfer. The Rieske subunit acts by binding either a ubiquinol or plastoquinol anion, transferring an electron to the 2Fe-2S cluster, then releasing the electron to the cytochrome c or cytochrome f haem iron
COORDINATES: similar to AA sequence:RefSeq:WP_007151055.1
atp + pyruvate + H(2)O = amp + phosphoenolpyruvate + phosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_014994699.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0008986 - pyruvate, water dikinase activity [Evidence IEA]; GO:0016772 - transferase activity, transferring phosphorus-containing groups [Evidence IEA]
GO:0016310 - phosphorylation [Evidence IEA]; GO:0006090 - pyruvate metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011588709.1
pyruvate, water dikinase regulatory protein
COORDINATES: similar to AA sequence:RefSeq:WP_014994702.1
GO:0051537 - 2 iron, 2 sulfur cluster binding [Evidence IEA]; GO:0047547 - 2-methylcitrate dehydratase activity [Evidence IEA]
GO:0019679 - propionate metabolic process, methylcitrate cycle [Evidence IEA]
bifunctional 2-methylcitrate dehydratase/aconitate hydratase
COORDINATES: similar to AA sequence:RefSeq:WP_015486795.1
GO:0019629 - propionate catabolic process, 2-methylcitrate cycle [Evidence IEA]
2-methylaconitate cis-trans isomerase PrpF
COORDINATES: similar to AA sequence:RefSeq:WP_008735540.1
GO:0047456 - 2-methylisocitrate dehydratase activity [Evidence IEA]
Fe/S-dependent 2-methylisocitrate dehydratase AcnD
COORDINATES: similar to AA sequence:RefSeq:WP_007150437.1
GO:0050440 - 2-methylcitrate synthase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149117.1
GO:0046421 - methylisocitrate lyase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149424.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930534.1
anthranilate synthase component I family protein
COORDINATES: similar to AA sequence:RefSeq:WP_007151382.1
bifunctional phosphoserine phosphatase/homoserine phosphotransferase ThrH
positive regulator of gene expression for the cysteine regulon
COORDINATES: similar to AA sequence:RefSeq:WP_007149757.1
COORDINATES: similar to AA sequence:RefSeq:WP_008735513.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148729.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148920.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930287.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149310.1
catalyzes the exchange of initiation factor 2-bound gdp for gtp (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_011588725.1
GO:0046523 - S-methyl-5-thioribose-1-phosphate isomerase activity [Evidence IEA]
GO:0019509 - L-methionine salvage from methylthioadenosine [Evidence IEA]
S-methyl-5-thioribose-1-phosphate isomerase
COORDINATES: similar to AA sequence:RefSeq:WP_011588726.1
methylthioribulose 1-phosphate dehydratase
COORDINATES: similar to AA sequence:RefSeq:WP_011588727.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149273.1
GO:0016862 - intramolecular oxidoreductase activity, interconverting keto- and enol-groups [Evidence IEA]; GO:0016791 - phosphatase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008930294.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148411.1
GO:0004386 - helicase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149727.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588732.1
DUF3488 and transglutaminase-like domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_008928493.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150232.1
converts O-succinylhomoserine into homocysteine.
COORDINATES: similar to AA sequence:RefSeq:WP_007150458.1
GO:0071268 - homocysteine biosynthetic process [Evidence IEA]; GO:0019346 - transsulfuration [Evidence IEA]
Glutamine phosphoribosylpyrophosphate amidotransferase
COORDINATES: similar to AA sequence:RefSeq:WP_007148625.1
GO:0004044 - amidophosphoribosyltransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011588737.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151275.1
Folylpolyglutamate synthetase catalyzes anATP-dependent ligation reaction that results in the synthesis of poly(gamma-glutamate) metabolites of folates and some antifolates
COORDINATES: similar to AA sequence:RefSeq:WP_007151298.1
folylpolyglutamate synthase/dihydrofolate synthase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_011588740.1
acetyl-CoA carboxylase, carboxyltransferase subunit beta
the alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate. L-serine + 1-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + glyceraldehyde 3-phosphate + H2O.
COORDINATES: similar to AA sequence:RefSeq:WP_007149825.1
GO:0004834 - tryptophan synthase activity [Evidence IEA]
GO:0000162 - tryptophan biosynthetic process [Evidence IEA]
the beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. L-serine + 1-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + glyceraldehyde 3-phosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_007148923.1
N-(5'-phospho-beta-D-ribosyl)-anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_011588743.1
GO:0004640 - phosphoribosylanthranilate isomerase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011588744.1
COORDINATES: protein motif:HMM:TIGR03505.1
L-aspartate-4-semialdehyde + phosphate + NADP(+) = L-4-aspartyl phosphate + NADPH.
COORDINATES: similar to AA sequence:RefSeq:WP_011588746.1
GO:0004073 - aspartate-semialdehyde dehydrogenase activity [Evidence IEA]; GO:0051287 - NAD binding [Evidence IEA]; GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]
GO:0008652 - amino acid biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_019622284.1
GO:0004073 - aspartate-semialdehyde dehydrogenase activity [Evidence IEA]
catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. the product decarboxylates to 4-methyl-2-oxopentanoate. 3-carboxy-2-hydroxy-4-methylpentanoate + NAD(+) = 3-carboxy-4-methyl-2-oxopentanoate + NADH.
COORDINATES: similar to AA sequence:RefSeq:WP_007151605.1
GO:0003862 - 3-isopropylmalate dehydrogenase activity [Evidence IEA]
GO:0009098 - leucine biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148799.1
catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate. 3-isopropylmalate = 2-isopropylmaleate + H(2)O. 2-isopropylmaleate + H(2)O = 2-isopropylmalate.
COORDINATES: similar to AA sequence:RefSeq:WP_011588750.1
GO:0009316 - 3-isopropylmalate dehydratase complex [Evidence IEA]
GO:0003861 - 3-isopropylmalate dehydratase activity [Evidence IEA]
3-isopropylmalate dehydratase small subunit
COORDINATES: similar to AA sequence:RefSeq:WP_035460343.1
3-isopropylmalate dehydratase large subunit
COORDINATES: similar to AA sequence:RefSeq:WP_007150235.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928472.1
catalyzes the transformation of 5-enolpyruvylshikimate 3-phosphate to chorismate in the last step of the shikimate pathway. 5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_011588754.1
GO:0004107 - chorismate synthase activity [Evidence IEA]
GO:0009073 - aromatic amino acid family biosynthetic process [Evidence IEA]
s-adenosyl-l-methionine + dna adenine = s-adenosyl-l-homocysteine + dna 6-methylaminopurine.
COORDINATES: similar to AA sequence:RefSeq:WP_014994982.1
GO:0008276 - protein methyltransferase activity [Evidence IEA]; GO:0008757 - S-adenosylmethionine-dependent methyltransferase activity [Evidence IEA]
GO:0018364 - peptidyl-glutamine methylation [Evidence IEA]; GO:0042273 - ribosomal large subunit biogenesis [Evidence IEA]
50S ribosomal protein L3 N(5)-glutamine methyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_007150384.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148728.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928466.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148835.1
dicarboxylate/amino acid:cation symporter
COORDINATES: similar to AA sequence:RefSeq:WP_007150122.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148807.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151245.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150823.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149958.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148549.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150239.1
It removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction. It exhibits 3'-5'-exonuclease,3'-phosphomonoesterase, 3'-repair diesterase and ribonuclease h activities. Catalytic activity: degradation of double-stranded DNA. It acts progressively in a 3'- to 5'-direction, releasing nucleoside 5'- phosphates.
COORDINATES: similar to AA sequence:RefSeq:WP_007150217.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0004519 - endonuclease activity [Evidence IEA]; GO:0008853 - exodeoxyribonuclease III activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150460.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151305.1
sn-glycerol 3-phosphate + nad(p)(+) = glycerone phosphate + nad(p)h
COORDINATES: similar to AA sequence:RefSeq:WP_011588769.1
GO:0009331 - glycerol-3-phosphate dehydrogenase complex [Evidence IEA]
GO:0047952 - glycerol-3-phosphate dehydrogenase [NAD(P)+] activity [Evidence IEA]; GO:0051287 - NAD binding [Evidence IEA]
GO:0046168 - glycerol-3-phosphate catabolic process [Evidence IEA]; GO:0006072 - glycerol-3-phosphate metabolic process [Evidence IEA]
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase
molecular chaperone. has atpase activity
COORDINATES: similar to AA sequence:RefSeq:WP_011588770.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0016887 - ATP hydrolysis activity [Evidence IEA]; GO:0051082 - unfolded protein binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150443.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150109.1
COORDINATES: similar to AA sequence:RefSeq:WP_013345992.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149713.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0003824 - catalytic activity [Evidence IEA]; GO:0046872 - metal ion binding [Evidence IEA]
ADP-forming succinate--CoA ligase subunit beta
the branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-coa and co(2). it contains multiple copies of 3 enzymatic components: branched-chain alpha-keto acid decarboxylase (e1), lipoamide acyltransferase (e2) and lipoamide dehydrogenase (e3)
COORDINATES: similar to AA sequence:RefSeq:WP_011588775.1
GO:0004148 - dihydrolipoyl dehydrogenase activity [Evidence IEA]
GO:0045454 - cell redox homeostasis [Evidence IEA]; GO:0051068 - dihydrolipoamide metabolic process [Evidence IEA]; GO:0006096 - glycolytic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149212.1
GO:0045252 - oxoglutarate dehydrogenase complex [Evidence IEA]
GO:0004149 - dihydrolipoyllysine-residue succinyltransferase activity [Evidence IEA]
2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase
the 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-coa & co(2) (2-oxoglutarate + lipoamide = s-succinyldihydrolipoamide + co(2))
COORDINATES: similar to AA sequence:RefSeq:WP_011588777.1
GO:0004591 - oxoglutarate dehydrogenase (succinyl-transferring) activity [Evidence IEA]; GO:0030976 - thiamine pyrophosphate binding [Evidence IEA]
2-oxoglutarate dehydrogenase E1 component
COORDINATES: similar to AA sequence:RefSeq:WP_011588778.1
succinate dehydrogenase iron-sulfur subunit
COORDINATES: similar to AA sequence:RefSeq:WP_007148541.1
GO:0022900 - electron transport chain [Evidence IEA]; GO:0006099 - tricarboxylic acid cycle [Evidence IEA]
succinate dehydrogenase flavoprotein subunit
this is the hydrophobic component of the succinate dehydrogenase complex. it is suggested that it is required to anchor the catalytic components to the cytoplasmic membrane
COORDINATES: similar to AA sequence:RefSeq:WP_007150974.1
GO:0045282 - plasma membrane succinate dehydrogenase complex [Evidence IEA]
GO:0000104 - succinate dehydrogenase activity [Evidence IEA]
succinate dehydrogenase, hydrophobic membrane anchor protein
mono-heme cytochrome of the succinate dehydrogenase complex (by similarity)
COORDINATES: similar to AA sequence:RefSeq:WP_008928438.1
succinate dehydrogenase, cytochrome b556 subunit
acetyl-coa + h(2)o + oxaloacetate = citrate + coa.
COORDINATES: similar to AA sequence:RefSeq:WP_008928437.1
GO:0004108 - citrate (Si)-synthase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008928436.1
SMP-30/gluconolactonase/LRE family protein
COORDINATES: similar to AA sequence:RefSeq:WP_008928435.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149418.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588786.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149585.1
COG: Outer membrane receptor proteins, mostly Fe transport
COORDINATES: similar to AA sequence:RefSeq:WP_008735146.1
COORDINATES: similar to AA sequence:RefSeq:WP_008735145.1
atp + l-glutamate + trna(glu) = amp + diphosphate + l-glutamyl-trna(glu).
COORDINATES: similar to AA sequence:RefSeq:WP_011588790.1
GO:0009332 - glutamate-tRNA ligase complex [Evidence IEA]
GO:0004818 - glutamate-tRNA ligase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148477.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588792.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150267.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148756.1
GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; GO:0017150 - tRNA dihydrouridine synthase activity [Evidence IEA]
GO:0002943 - tRNA dihydrouridine synthesis [Evidence IEA]
tRNA dihydrouridine(20/20a) synthase DusA
sedoheptulose 7-phosphate + d-glyceraldehyde 3-phosphate = d-erythrose 4-phosphate + d-fructose 6-phosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_011396244.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930339.1
TerB family tellurite resistance protein
COORDINATES: similar to AA sequence:RefSeq:WP_007149382.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149204.1
putative DNA-binding domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_011588799.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150356.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148801.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151176.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151148.1
COORDINATES: similar to AA sequence:RefSeq:WP_014994828.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150438.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149345.1
transporter substrate-binding domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_008928430.1
thrombospondin type 3 repeat-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_007150351.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928428.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928427.1
protein l-methionine + oxidized thioredoxin = protein l-methionine s-oxide + reduced thioredoxin.
COORDINATES: similar to AA sequence:RefSeq:WP_011588811.1
GO:0033744 - L-methionine:thioredoxin-disulfide S-oxidoreductase activity [Evidence IEA]; GO:0008113 - peptide-methionine (S)-S-oxide reductase activity [Evidence IEA]
GO:0030091 - protein repair [Evidence IEA]; GO:0006979 - response to oxidative stress [Evidence IEA]
peptide-methionine (S)-S-oxide reductase MsrA
COORDINATES: similar to AA sequence:RefSeq:WP_008928425.1
GO:0033743 - peptide-methionine (R)-S-oxide reductase activity [Evidence IEA]
peptide-methionine (R)-S-oxide reductase MsrB
COORDINATES: similar to AA sequence:RefSeq:WP_007148356.1
COORDINATES: similar to AA sequence:RefSeq:WP_008737950.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588815.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151125.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150796.1
GO:0018784 - (S)-2-haloacid dehalogenase activity [Evidence IEA]
GO:0006805 - xenobiotic metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_019621747.1
COORDINATES: similar to AA sequence:RefSeq:WP_012069606.1
functions as an aerobic enzyme in the citric acid cycle
COORDINATES: similar to AA sequence:RefSeq:WP_008928418.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150930.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588823.1
COORDINATES: similar to AA sequence:RefSeq:WP_014994223.1
catalyzes the reduction of arsenate to arsenite
COORDINATES: similar to AA sequence:RefSeq:WP_007151223.1
GO:0008794 - arsenate reductase (glutaredoxin) activity [Evidence IEA]
This arsenate reductase requires both glutathione and glutaredoxin to convert arsenate to arsenite, after which the efflux transporter formed by ArsA and ArsB can extrude the arsenite from the cell, providing resistance; Derived by automated computational analysis using gene prediction method: Protein Homology.
involved in tryptophan uptake and utilization.
COORDINATES: similar to AA sequence:RefSeq:WP_007150958.1
GO:0010181 - FMN binding [Evidence IEA]; GO:0003955 - NAD(P)H dehydrogenase (quinone) activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149050.1
COORDINATES: similar to AA sequence:RefSeq:WP_014994219.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148985.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149319.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148572.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151047.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150655.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148330.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928403.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149092.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151273.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149368.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928402.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148318.1
COORDINATES: similar to AA sequence:RefSeq:WP_014995161.1
GO:0097163 - sulfur carrier activity [Evidence IEA]
GO:0002143 - tRNA wobble position uridine thiolation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008928393.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588843.1
23S rRNA (cytidine(2498)-2'-O)-methyltransferase RlmM
COORDINATES: similar to AA sequence:RefSeq:WP_011588844.1
GO:0008864 - formyltetrahydrofolate deformylase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011588845.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148876.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588847.1
3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_008928386.1
GO:0016747 - acyltransferase activity, transferring groups other than amino-acyl groups [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148520.1
glutathione S-transferase N-terminal domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_007149014.1
conversion of nadph, generated by peripheral catabolic pathways, to nadh, which can enter the respiratory chain for energy generation
COORDINATES: similar to AA sequence:RefSeq:WP_011588851.1
GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; GO:0003957 - NAD(P)+ transhydrogenase (B-specific) activity [Evidence IEA]
GO:0045454 - cell redox homeostasis [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149351.1
GO:0016818 - hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [Evidence IEA]
GO:0032297 - negative regulation of DNA-templated DNA replication initiation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007151425.1
Phosphoribosylaminoimidazole (AIR) synthetase
COORDINATES: similar to AA sequence:RefSeq:WP_011588854.1
GO:0004641 - phosphoribosylformylglycinamidine cyclo-ligase activity [Evidence IEA]
GO:0006189 - 'de novo' IMP biosynthetic process [Evidence IEA]; GO:0009152 - purine ribonucleotide biosynthetic process [Evidence IEA]
phosphoribosylformylglycinamidine cyclo-ligase
uses formyl tetrahydrofolate as a formyl group donor to produce 5'-phosphoribosyl-N-formylglycinamide
COORDINATES: similar to AA sequence:RefSeq:WP_008736975.1
GO:0004644 - phosphoribosylglycinamide formyltransferase activity [Evidence IEA]
phosphoribosylglycinamide formyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_008928376.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928375.1
hydrolyzes dUTP to dUMP and pyrophosphate
COORDINATES: similar to AA sequence:RefSeq:WP_004922407.1
GO:0008829 - dCTP deaminase activity [Evidence IEA]
GO:0009394 - 2'-deoxyribonucleotide metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008928373.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0016887 - ATP hydrolysis activity [Evidence IEA]; GO:0051536 - iron-sulfur cluster binding [Evidence IEA]
iron-sulfur cluster carrier protein ApbC
COORDINATES: similar to AA sequence:RefSeq:WP_007149105.1
The SIMPL domain is named for its presence in mouse protein SIMPL (signalling molecule that associates with mouse pelle-like kinase). Bacterial member BP26, from Brucella, was shown to assemble into a channel-like structure, while YggE from E. coli has been associated with resistance to oxidative stress; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_007151193.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150439.1
GO:0004806 - triglyceride lipase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007151624.1
GO:0003684 - damaged DNA binding [Evidence IEA]
translesion error-prone DNA polymerase V subunit UmuC
COORDINATES: similar to AA sequence:RefSeq:WP_007149267.1
translesion error-prone DNA polymerase V autoproteolytic subunit
COORDINATES: similar to AA sequence:RefSeq:WP_007151460.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151323.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588867.1
. catalyzes the cleavage of the glycosidic bonds between n-acetylmuramic acid and n-acetylglucosamine residues in peptidoglycan. may play a role in recycling of muropeptides during cell elongation and/or cell division.
COORDINATES: similar to AA sequence:RefSeq:WP_007149708.1
nvolved in the fifth (last) step in the biosynthesis of spermidine from arginine and methionine.
COORDINATES: similar to AA sequence:RefSeq:WP_007150420.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149263.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151282.1
COORDINATES: similar to AA sequence:RefSeq:WP_016853657.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588873.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148864.1
GO:0003824 - catalytic activity [Evidence IEA]; GO:0051536 - iron-sulfur cluster binding [Evidence IEA]
gdh catalyzes the reversible oxidative deamination of glutamate to 2-oxooglutarate and ammonia.
COORDINATES: similar to AA sequence:RefSeq:WP_007148436.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148927.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151614.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150266.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928199.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0004825 - methionine-tRNA ligase activity [Evidence IEA]; GO:0000166 - nucleotide binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149074.1
Crp/Fnr family transcriptional regulator
COORDINATES: similar to AA sequence:RefSeq:WP_008928196.1
class II aldolase/adducin family protein
COORDINATES: similar to AA sequence:RefSeq:WP_007150245.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150846.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928031.1
COORDINATES: similar to AA sequence:RefSeq:WP_010629381.1
may be part of a membrane complex involved in electron transport
COORDINATES: similar to AA sequence:RefSeq:WP_011588890.1
GO:0022900 - electron transport chain [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008928034.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149646.1
GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; GO:0009055 - electron transfer activity [Evidence IEA]
may be part of a membrane complex involved in nitrogen fixation
COORDINATES: similar to AA sequence:RefSeq:WP_011588893.1
GO:0022900 - electron transport chain [Evidence IEA]; GO:0055085 - transmembrane transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148460.1
GO:0009055 - electron transfer activity [Evidence IEA]; GO:0010181 - FMN binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008928038.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150185.1
glycine zipper 2TM domain-containing protein
gltS is responsible for the sodium-dependent uptake of extracellular glutamate.
COORDINATES: similar to AA sequence:RefSeq:WP_007151053.1
GO:0015501 - glutamate:sodium symporter activity [Evidence IEA]
GO:0015813 - L-glutamate transmembrane transport [Evidence IEA]
Has both an apurinic and/or apyrimidinic endonuclease activity and a DNA n-glycosylase activity. Incises damaged DNA at cytosines, thymines and guanines. Acts on a damaged strand, 5' from the damaged site. Required for the repair of both oxidative DNA damage and spontaneous mutagenic lesions. Catalytic activity: the c-o-p bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_007149505.1
GO:0003906 - DNA-(apurinic or apyrimidinic site) endonuclease activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150937.1
COORDINATES: similar to AA sequence:RefSeq:WP_014994048.1
forms anion selective channels (by similarity)
COORDINATES: similar to AA sequence:RefSeq:WP_008929422.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929423.1
nucleoside triphosphate pyrophosphohydrolase
COORDINATES: similar to AA sequence:RefSeq:WP_008929424.1
GO:0015969 - guanosine tetraphosphate metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011588905.1
GO:0008173 - RNA methyltransferase activity [Evidence IEA]
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD
Predicted 3'-5' exonuclease related to the exonuclease domain of PolB
COORDINATES: similar to AA sequence:RefSeq:WP_014993899.1
two cysteine synthase enzymes are found. both catalyze the same reaction. cysteine synthase B can also use thiosulfate in place of sulfide to give cysteine thiosulfonate as a product. O(3)-acetyl-L-serine + H(2)S = L-cysteine + acetate.
COORDINATES: similar to AA sequence:RefSeq:WP_014993898.1
COORDINATES: similar to AA sequence:RefSeq:WP_014993897.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151190.1
GO:0033856 - pyridoxine 5'-phosphate synthase activity [Evidence IEA]
Involved in DNA repair and recF pathway recombination
COORDINATES: similar to AA sequence:RefSeq:WP_014993895.1
binds both GDP and GTP, has an intrinsic GTPase activity and is essential for cell growth (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_008929431.1
GO:0005525 - GTP binding [Evidence IEA]; GO:0003723 - RNA binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011588912.1
GO:0004525 - ribonuclease III activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_014993892.1
remove the signal peptides from secretory proteins
COORDINATES: similar to AA sequence:RefSeq:WP_007150499.1
GO:0009306 - protein secretion [Evidence IEA]; GO:0006465 - signal peptide processing [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008929435.1
GO:0005525 - GTP binding [Evidence IEA]; GO:0003924 - GTPase activity [Evidence IEA]
repression of the alginate biosynthesis by attenutation of AlgU acrivity
COORDINATES: similar to AA sequence:RefSeq:WP_019018688.1
Positive regulator for alginate biosynthesis
COORDINATES: similar to AA sequence:RefSeq:WP_007150849.1
SoxR reducing system RseC family protein
Repression of alginate biosynthesis by attenuating the expression of algU
COORDINATES: similar to AA sequence:RefSeq:WP_008929438.1
MucB/RseB C-terminal domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_007150750.1
sigma-E factor negative regulatory protein
COORDINATES: similar to AA sequence:RefSeq:WP_014993885.1
GO:0016987 - sigma factor activity [Evidence IEA]
GO:0006352 - DNA-templated transcription initiation [Evidence IEA]; GO:0006979 - response to oxidative stress [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148757.1
catalyzes the oxidation of l-aspartate to iminoaspartate: l-aspartate + h(2)o + o(2) = oxaloacetate + nh(3) + h(2)o(2)
COORDINATES: similar to AA sequence:RefSeq:WP_007150586.1
GO:0008734 - L-aspartate oxidase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149725.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148457.1
succinate dehydrogenase assembly factor 2
COORDINATES: similar to AA sequence:RefSeq:WP_011588925.1
catalyze the reversible hydration of alpha,beta-unsaturated enoyl-CoA substrates to the corresponding beta-hydroxyacyl-CoA products
COORDINATES: similar to AA sequence:RefSeq:WP_014993879.1
Excises uracil residues from the DNA which can arise as a result of misincorporation of dump residues by DNA polymerase or due to deamination of cytosine.
COORDINATES: similar to AA sequence:RefSeq:WP_007148651.1
GO:0016799 - hydrolase activity, hydrolyzing N-glycosyl compounds [Evidence IEA]; GO:0004844 - uracil DNA N-glycosylase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148748.1
atp + l-lysine + trna(lys) = amp + diphosphate + l-lysyl-trna(lys).
COORDINATES: similar to AA sequence:RefSeq:WP_007148769.1
GO:0004824 - lysine-tRNA ligase activity [Evidence IEA]
GO:0006430 - lysyl-tRNA aminoacylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_156964877.1
programmed frameshift; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_007148998.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929451.1
GO:0008297 - single-stranded DNA exodeoxyribonuclease activity [Evidence IEA]
single-stranded-DNA-specific exonuclease RecJ
COORDINATES: similar to AA sequence:RefSeq:WP_011588933.1
GO:0070403 - NAD+ binding [Evidence IEA]; GO:0016491 - oxidoreductase activity [Evidence IEA]
fatty acid oxidation complex subunit alpha FadB
acyl-CoA + acetyl-CoA= CoA + 3-oxoacyl-CoA
COORDINATES: similar to AA sequence:RefSeq:WP_011784654.1
GO:0003988 - acetyl-CoA C-acyltransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_019020781.1
COORDINATES: similar to AA sequence:RefSeq:WP_009833844.1
GO:0004089 - carbonate dehydratase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011978180.1
COORDINATES: protein motif:HMM:NF012372.2
GO:0003886 - DNA (cytosine-5-)-methyltransferase activity [Evidence IEA]
GO:0006304 - DNA modification [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148474.1
COORDINATES: similar to AA sequence:RefSeq:WP_002885324.1
dna-binding protein that preferentially recognizes a curved dna sequence
COORDINATES: similar to AA sequence:RefSeq:WP_012071006.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930188.1
exact function of these domains is unknown,however it isthought that they bind to some as yet unidentified small molecule (perhaps with an adenosyl moiety) and regulate the activity of attached enzymatic or other domains.
COORDINATES: similar to AA sequence:RefSeq:WP_007151042.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930182.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151328.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151200.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151088.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149774.1
COORDINATES: protein motif:HMM:NF023164.2
COORDINATES: protein motif:HMM:NF024116.2
COORDINATES: protein motif:HMM:NF012235.2
COORDINATES: protein motif:HMM:NF022439.2
COORDINATES: protein motif:HMM:NF015180.2
COORDINATES: similar to AA sequence:RefSeq:WP_007151404.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149695.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151489.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148643.1
GO:0008270 - zinc ion binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008733687.1
catalyzes the third step in the de novo biosynthesis of pyrimidine, the conversion of ureidosuccinic acid (N-carbamoyl-L-aspartate) into dihydroorotate
COORDINATES: similar to AA sequence:RefSeq:WP_013662540.1
GO:0016810 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008930202.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149929.1
cysH catalyzes reduction of activated sulfate into sulfite. adenosine 3',5'-bisphosphate + sulfite + oxidized thioredoxin = 3'-phosphoadenylyl sulfate + reduced thioredoxin.
COORDINATES: similar to AA sequence:RefSeq:WP_007149311.1
GO:0003824 - catalytic activity [Evidence IEA]; GO:0004604 - phosphoadenylyl-sulfate reductase (thioredoxin) activity [Evidence IEA]
GO:0019379 - sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011588968.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150829.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149723.1
COORDINATES: similar to AA sequence:RefSeq:WP_008738689.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588973.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588974.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151072.1
COORDINATES: similar to AA sequence:RefSeq:WP_011588976.1
COORDINATES: similar to AA sequence:RefSeq:WP_013970282.1
responsible for catalyzing the direct reduction of 4-Nitrobenzoate to 4-hydroxyaminobenzoate with the oxidation of 2 mol of NADH per mol of 4 NBen
COORDINATES: similar to AA sequence:RefSeq:WP_007149046.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150434.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150127.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150730.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151215.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149388.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150890.1
metalloregulator ArsR/SmtB family transcription factor
reduces a range of alternative electron acceptors
COORDINATES: similar to AA sequence:RefSeq:WP_007151602.1
NADH:flavin oxidoreductase/NADH oxidase family protein
catalyzes the nadp-dependent reduction of 2,4-dienoyl- coa to yield trans-2- enoyl-coa
COORDINATES: similar to AA sequence:RefSeq:WP_011588986.1
NADPH-dependent 2,4-dienoyl-CoA reductase
COORDINATES: similar to AA sequence:RefSeq:WP_008927547.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149606.1
COORDINATES: similar to AA sequence:RefSeq:WP_014993822.1
COORDINATES: similar to AA sequence:RefSeq:WP_014993821.1
COORDINATES: protein motif:HMM:NF015378.2
COORDINATES: similar to AA sequence:RefSeq:WP_008927549.1
COORDINATES: similar to AA sequence:RefSeq:WP_014993816.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927553.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148364.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148990.1
Ferredoxin (flavodoxin)-NADP(H) reductases (FNR) are ubiquitous flavoenzymes that deliver NADPH or low potential one-electron donors (ferredoxin, flavodoxin) to redox-based metabolisms
COORDINATES: similar to AA sequence:RefSeq:WP_007151529.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150637.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148368.1
MaoC/PaaZ C-terminal domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_011589001.1
GO:0043828 - tRNA 2-selenouridine synthase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149800.1
putative selenate ABC transporter substrate-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_007149849.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151084.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149271.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148569.1
GO:0004756 - selenide, water dikinase activity [Evidence IEA]
GO:0001887 - selenium compound metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149305.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150233.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150056.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149225.1
COORDINATES: similar to AA sequence:RefSeq:WP_018917055.1
COORDINATES: similar to AA sequence:RefSeq:WP_010323213.1
COORDINATES: similar to AA sequence:RefSeq:WP_015486040.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928580.1
esterase-like activity of phytase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_011589015.1
tRNA (pseudouridine(54)-N(1))-methyltransferase TrmY
COORDINATES: similar to AA sequence:RefSeq:WP_011589016.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589017.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149448.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150468.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150004.1
helix-hairpin-helix domain-containing protein
catalyzes the last step in the de novo biosynthesis of pyrimidines, the decarboxylation of OMP into UMP
COORDINATES: similar to AA sequence:RefSeq:WP_011589022.1
GO:0004590 - orotidine-5'-phosphate decarboxylase activity [Evidence IEA]
GO:0006207 - 'de novo' pyrimidine nucleobase biosynthetic process [Evidence IEA]; GO:0044205 - 'de novo' UMP biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008929894.1
lipopolysaccharide assembly protein LapB
COORDINATES: similar to AA sequence:RefSeq:WP_007148948.1
lipopolysaccharide assembly protein LapA domain-containing protein
DNA binding activity. This protein is one of the two subunits of integration host factor, a specific dna-binding protein that functions in genetic recombination as well as in transcriptional and translational control (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_020583313.1
GO:0006310 - DNA recombination [Evidence IEA]; GO:0075713 - establishment of integrated proviral latency [Evidence IEA]; GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]; GO:0006417 - regulation of translation [Evidence IEA]
ribosomal protein S1 binds mRNA; thus facilitating recognition of the initiation point. it is needed to translate mRNA with a short Shine-Dalgarno (sd) purine-rich sequence.
COORDINATES: similar to AA sequence:RefSeq:WP_011589026.1
phosphorylation of cytidine 5'-monophosphate (dCMP) to cytidine 5'-diphosphate (dCDP) in the presence of ATP or GTP
COORDINATES: similar to AA sequence:RefSeq:WP_014995309.1
GO:0004127 - cytidylate kinase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149164.1
GO:0008977 - prephenate dehydrogenase (NAD+) activity [Evidence IEA]
bifunctional prephenate dehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_007148619.1
chorismate = prephenate and prephenate = phenylpyruvate + H(2)O + CO(2).
COORDINATES: similar to AA sequence:RefSeq:WP_016913752.1
GO:0004664 - prephenate dehydratase activity [Evidence IEA]
GO:0009094 - L-phenylalanine biosynthetic process [Evidence IEA]
O-phospho-L-serine + 2-oxoglutarate = 3-phosphonooxypyruvate + L-glutamate.
COORDINATES: similar to AA sequence:RefSeq:WP_007151071.1
GO:0003824 - catalytic activity [Evidence IEA]; GO:0004648 - O-phospho-L-serine:2-oxoglutarate aminotransferase activity [Evidence IEA]
GO:0006564 - L-serine biosynthetic process [Evidence IEA]
3-phosphoserine/phosphohydroxythreonine transaminase
DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings. Catalytic activity: ATP-dependent breakage,passage and rejoining of double-stranded DNA. Subunit made up of two chains. The A chain is responsible for DNA breakage and rejoining; the B chain catalyzes ATP hydrolysis. The enzyme forms an a2b2 tetramer.
COORDINATES: similar to AA sequence:RefSeq:WP_008929885.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0003677 - DNA binding [Evidence IEA]; GO:0003916 - DNA topoisomerase activity [Evidence IEA]; GO:0003918 - DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [Evidence IEA]
GO:0006259 - DNA metabolic process [Evidence IEA]; GO:0006265 - DNA topological change [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011589033.1
COORDINATES: similar to AA sequence:RefSeq:WP_013660634.1
GO:0008689 - 3-demethylubiquinone-9 3-O-methyltransferase activity [Evidence IEA]
bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG
COORDINATES: similar to AA sequence:RefSeq:WP_007149859.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151550.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149124.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149097.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151242.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929877.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151554.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149028.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149458.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929873.1
COORDINATES: similar to AA sequence:RefSeq:WP_008735033.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929871.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149287.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589048.1
cleaves multimeric trna precursor at the spacer region.
COORDINATES: similar to AA sequence:RefSeq:WP_008929868.1
GO:0016891 - endoribonuclease activity, producing 5'-phosphomonoesters [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007151623.1
GO:0004619 - phosphoglycerate mutase activity [Evidence IEA]
2,3-diphosphoglycerate-dependent phosphoglycerate mutase
COORDINATES: similar to AA sequence:RefSeq:WP_007150695.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929858.1
May play a role in DNA repair. It seems to be involved in an recBC-independent recombinational process of DNA repair. It may act with recF and recO.
COORDINATES: similar to AA sequence:RefSeq:WP_011589054.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149395.1
YbaB/EbfC family nucleoid-associated protein
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. Function: the tau chain serves as a scaffold to help in the dimerizaton of the core complex; the gamma chain seems to interact with the delta subunit to transfer the beta subunit on the DNA.
COORDINATES: similar to AA sequence:RefSeq:WP_007149796.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0003677 - DNA binding [Evidence IEA]; GO:0003887 - DNA-directed DNA polymerase activity [Evidence IEA]
signal recognition particle sRNA small type
COORDINATES: nucleotide motif:Rfam:14.4:RF00169
reversibly catalyses the oxidation and phosphorylation of D-glyceraldehyde-3-phosphate to 1,3-diphospho- glycerate
COORDINATES: similar to AA sequence:RefSeq:WP_007149784.1
GO:0006094 - gluconeogenesis [Evidence IEA]; GO:0019682 - glyceraldehyde-3-phosphate metabolic process [Evidence IEA]; GO:0006096 - glycolytic process [Evidence IEA]
type I glyceraldehyde-3-phosphate dehydrogenase
COORDINATES: similar to AA sequence:RefSeq:WP_007148936.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148897.1
COORDINATES: similar to AA sequence:RefSeq:WP_014995347.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589061.1
COORDINATES: protein motif:HMM:NF013786.2
GO:0008897 - holo-[acyl-carrier-protein] synthase activity [Evidence IEA]; GO:0000287 - magnesium ion binding [Evidence IEA]
4'-phosphopantetheinyl transferase superfamily protein
COORDINATES: protein motif:HMM:NF012427.2
COORDINATES: protein motif:HMM:NF012873.2
COORDINATES: similar to AA sequence:RefSeq:WP_076611583.1
frameshifted; internal stop; incomplete; partial in the middle of a contig; missing N-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_076611750.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0004803 - transposase activity [Evidence IEA]
GO:0006313 - transposition, DNA-mediated [Evidence IEA]
frameshifted; internal stop; incomplete; partial in the middle of a contig; missing C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_008930496.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150581.1
take part in pathways involving acetyl-CoA
COORDINATES: similar to AA sequence:RefSeq:WP_007149970.1
acetyl-CoA hydrolase/transferase C-terminal domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_007149985.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150181.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149678.1
GO:0004151 - dihydroorotase activity [Evidence IEA]
Carbon storage regulator (could also regulate swarming and quorum sensing)
COORDINATES: similar to AA sequence:RefSeq:WP_014995428.1
ATP + L-aspartate = ADP + 4-phospho-L-aspartate.
COORDINATES: similar to AA sequence:RefSeq:WP_007150585.1
GO:0004072 - aspartate kinase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_014995430.1
GO:0004813 - alanine-tRNA ligase activity [Evidence IEA]
GO:0006419 - alanyl-tRNA aminoacylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007151451.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151488.1
can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with lexa causing its activation and leading to its autocatalytic cleavage.
COORDINATES: similar to AA sequence:RefSeq:WP_007149154.1
GO:0008094 - ATP-dependent activity, acting on DNA [Evidence IEA]; GO:0003677 - DNA binding [Evidence IEA]
GO:0006310 - DNA recombination [Evidence IEA]; GO:0006281 - DNA repair [Evidence IEA]; GO:0009432 - SOS response [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007151337.1
COORDINATES: similar to AA sequence:RefSeq:WP_035461007.1
wax ester and triacylglycerol biosynthesis
COORDINATES: similar to AA sequence:RefSeq:WP_007151365.1
wax ester/triacylglycerol synthase family O-acyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_012068612.1
COORDINATES: similar to AA sequence:RefSeq:WP_014994405.1
class I adenylate-forming enzyme family protein
COORDINATES: similar to AA sequence:RefSeq:WP_076612015.1
this protein is involved in the repair of mismatches in DNA. it is possible that it carries out the mismatch recognition step. this protein has a weak ATPpase activity
COORDINATES: similar to AA sequence:RefSeq:WP_011589090.1
GO:0006298 - mismatch repair [Evidence IEA]
ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
COORDINATES: similar to AA sequence:RefSeq:WP_014851990.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150168.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149449.1
GO:0016740 - transferase activity [Evidence IEA]
TIGR04282 family arsenosugar biosynthesis glycosyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_007149475.1
TIGR04283 family arsenosugar biosynthesis glycosyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_010321955.1
Some members of this family are selenoproteins; Derived by automated computational analysis using gene prediction method: Protein Homology.
arsenosugar biosynthesis radical SAM protein ArsS
COORDINATES: similar to AA sequence:RefSeq:WP_007149801.1
PLDc N-terminal domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_007150256.1
phospholipase D-like domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_007148878.1
Exhibits a wide variety of catalytic activities including ATP-dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent helicase and DNA-dependent ATPase activities. Catalytic activity: exonucleolytic cleavage (in the presence of ATP) in either 5'- to 3'-or 3'- to 5'-direction to yield 5'- phosphooligonucleotides.
COORDINATES: similar to AA sequence:RefSeq:WP_008929787.1
GO:0009338 - exodeoxyribonuclease V complex [Evidence IEA]
GO:0008854 - exodeoxyribonuclease V activity [Evidence IEA]
Required for efficient DNA repair; it catalyzes the unwinding of double-stranded DNA and the cleavage of single- stranded DNA and it stimulates local genetic recombination. All of these activities require concomitant hydrolysis of ATP. Catalytic activity: exonucleolytic cleavage (in the presence of ATP) in either 5'- to 3'-or 3'- to 5'-direction to yield 5'- phosphooligonucleotides.
COORDINATES: similar to AA sequence:RefSeq:WP_014995480.1
Exhibits several catalytic activities, including ATP-dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at chi sequences, which locally stimulate recombination. Catalytic activity: exonucleolytic cleavage (in the presence of ATP) in either 5'- to 3'-or 3'- to 5'-direction to yield 5'-phosphooligonucleotides.
COORDINATES: similar to AA sequence:RefSeq:WP_008929785.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150870.1
COORDINATES: similar to AA sequence:RefSeq:WP_003096523.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149737.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149531.1
COORDINATES: similar to AA sequence:RefSeq:WP_009724589.1
COORDINATES: protein motif:HMM:NF014691.2
COORDINATES: protein motif:HMM:NF024977.2
essential role in the activity of both the modification methylase and the restriction endonuclease
COORDINATES: protein motif:HMM:NF013579.2
plays an essential role in the activity of both the modification methylase and the restriction endonuclease.
COORDINATES: similar to AA sequence:RefSeq:WP_012070879.1
class I SAM-dependent DNA methyltransferase
COORDINATES: protein motif:HMM:NF014680.2
COORDINATES: similar to AA sequence:RefSeq:WP_012070881.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0003677 - DNA binding [Evidence IEA]; GO:0016787 - hydrolase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149778.1
COORDINATES: similar to AA sequence:RefSeq:WP_014995412.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589116.1
COORDINATES: similar to AA sequence:RefSeq:WP_012613949.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151498.1
GO:0009328 - phenylalanine-tRNA ligase complex [Evidence IEA]
GO:0004826 - phenylalanine-tRNA ligase activity [Evidence IEA]
GO:0006432 - phenylalanyl-tRNA aminoacylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011589119.1
phenylalanine--tRNA ligase subunit alpha
COORDINATES: similar to AA sequence:RefSeq:WP_007151143.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929366.1
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. IF-3 is also a translational repressor protein, it controls the translation of its own gene by binding to its mRNA.
COORDINATES: similar to AA sequence:RefSeq:WP_011589120.1
COORDINATES: protein motif:HMM:NF024212.2
NAD(P)-binding domain-containing protein
COORDINATES: protein motif:HMM:NF019310.2
decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.
COORDINATES: similar to AA sequence:RefSeq:WP_018918693.1
COORDINATES: similar to AA sequence:RefSeq:WP_010331156.1
COORDINATES: similar to AA sequence:RefSeq:WP_003050052.1
GO:0043190 - ATP-binding cassette (ABC) transporter complex [Evidence IEA]; GO:0016020 - membrane [Evidence IEA]
GO:0005524 - ATP binding [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]
ribosome-associated ATPase/putative transporter RbbA
COORDINATES: similar to AA sequence:RefSeq:WP_011506733.1
COORDINATES: similar to AA sequence:RefSeq:WP_016914801.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0003922 - GMP synthase (glutamine-hydrolyzing) activity [Evidence IEA]; GO:0016462 - pyrophosphatase activity [Evidence IEA]
GO:0006177 - GMP biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004657166.1
GO:0003938 - IMP dehydrogenase activity [Evidence IEA]
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides. It can also degrade 3' or 5' ss regions extending from the termini of duplex DNA molecules and displaced ss regions. Catalytic activity: exonucleolytic cleavage in either 5'-to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.
COORDINATES: similar to AA sequence:RefSeq:WP_011589131.1
GO:0009318 - exodeoxyribonuclease VII complex [Evidence IEA]
GO:0008855 - exodeoxyribonuclease VII activity [Evidence IEA]
GO:0006308 - DNA catabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149817.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927654.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148978.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150450.1
GO:0005525 - GTP binding [Evidence IEA]; GO:0003924 - GTPase activity [Evidence IEA]; GO:0043022 - ribosome binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148606.1
outer membrane protein assembly factor BamB
COORDINATES: similar to AA sequence:RefSeq:WP_008927658.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589138.1
GO:0004821 - histidine-tRNA ligase activity [Evidence IEA]
GO:0006427 - histidyl-tRNA aminoacylation [Evidence IEA]
converts 2c-methyl-d-erythritol 2,4-cyclodiphosphate (me-2,4cpp) into 1-hydroxy-2-methyl-2-(e)-butenyl 4-diphosphate (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_011589139.1
GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity [Evidence IEA]
GO:0044237 - cellular metabolic process [Evidence IEA]
flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase
COORDINATES: similar to AA sequence:RefSeq:WP_007151429.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589141.1
type IV pilus biogenesis/stability protein PilW
COORDINATES: similar to AA sequence:RefSeq:WP_011589142.1
GO:0016433 - rRNA (adenine) methyltransferase activity [Evidence IEA]; GO:0008757 - S-adenosylmethionine-dependent methyltransferase activity [Evidence IEA]
23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN
COORDINATES: similar to AA sequence:RefSeq:WP_011589143.1
GO:0004550 - nucleoside diphosphate kinase activity [Evidence IEA]
GO:0006165 - nucleoside diphosphate phosphorylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_013331540.1
ATP binding component of ABC transporter
COORDINATES: similar to AA sequence:RefSeq:WP_011589145.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589146.1
GO:0005198 - structural molecule activity [Evidence IEA]
catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine. L-cysteine sulfinic acid is the best substrate. functions as a selenium delivery protein in the pathway for the biosynthesis of selenophosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_008043059.1
GO:0031071 - cysteine desulfurase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011589148.1
iron-sulfur cluster assembly accessory protein
Predicted metal-sulfur cluster biosynthetic enzyme
COORDINATES: similar to AA sequence:RefSeq:WP_007149671.1
putative Fe-S cluster assembly protein SufT
COORDINATES: similar to AA sequence:RefSeq:WP_014993547.1
catalyzes the removal of elemental sulfur and selenium atoms from cysteine and selenocysteine to produce alanine. functions as a sulfur delivery protein for NAD,biotin and Fe-S cluster synthesis. transfers sulfur on cys-456 of thii in a transpersulfidation reaction. functions also as a selenium delivery protein in the pathway for the biosynthesis of selenophosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_011589151.1
GO:0031071 - cysteine desulfurase activity [Evidence IEA]; GO:0030170 - pyridoxal phosphate binding [Evidence IEA]
GO:0044571 - [2Fe-2S] cluster assembly [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008927674.1
GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; GO:0003690 - double-stranded DNA binding [Evidence IEA]
Fe-S cluster assembly transcriptional regulator IscR
COORDINATES: protein motif:HMM:NF024685.2
COORDINATES: protein motif:HMM:NF013854.2
non-canonical purine NTP pyrophosphatase
COORDINATES: protein motif:HMM:NF013155.2
COORDINATES: similar to AA sequence:RefSeq:WP_007150800.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149952.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151255.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149151.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150039.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149779.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149087.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150449.1
COORDINATES: nucleotide motif:Rfam:14.4:RF00442
guanidine-I (ykkC/yxkD leader) riboswitch; Guanidine-I riboswitches control genes whose products are involved in modification or pumping out guanidine as a toxic compound from bacteria; This is class of guanidine riboswitches is based on the ykkC/yxkD leader; Derived by automated computational analysis using gene prediction method: cmsearch.
COORDINATES: similar to AA sequence:RefSeq:WP_007150509.1
putative urea ABC transporter substrate-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_008927688.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927689.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927690.1
urea carboxylase-associated family protein
COORDINATES: similar to AA sequence:RefSeq:WP_011589170.1
presumably two functions, contains domain for hydrolysis of urea and two allophanate hydrolase domains
COORDINATES: similar to AA sequence:RefSeq:WP_008927692.1
GO:0004847 - urea carboxylase activity [Evidence IEA]
GO:0019627 - urea metabolic process [Evidence IEA]
COORDINATES: protein motif:HMM:NF018599.2
COORDINATES: similar to AA sequence:RefSeq:WP_007148642.1
Binds to the RNA polymerase (RNAp). Its ATPase activity is stimulated by binding to RNAp.
COORDINATES: similar to AA sequence:RefSeq:WP_007148884.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0140658 - ATP-dependent chromatin remodeler activity [Evidence IEA]; GO:0016817 - hydrolase activity, acting on acid anhydrides [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149343.1
subunits i, ii and iii form the functional core of the enzyme complex
COORDINATES: similar to AA sequence:RefSeq:WP_011589176.1
exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper b into subunit i (by similarity)
COORDINATES: similar to AA sequence:RefSeq:WP_007148909.1
cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. subunits 1- 3 form the functional core of the enzyme complex. co i is the catalytic subunit of the enzyme. electrons originating in cytochrome c are transferred via the copper a center of subunit 2 and heme a of subunit 1 to the bimetallic center formed by heme a3 and copper b
COORDINATES: similar to AA sequence:RefSeq:WP_007150287.1
cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. subunits 1- 3 form the functional core of the enzyme complex. subunit 2 transfers the electrons from cytochrome c via its binuclear copper a center to the bimetallic center of the catalytic subunit 1
COORDINATES: similar to AA sequence:RefSeq:WP_014993502.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149300.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927703.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148351.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150619.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148383.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149599.1
GO:0008495 - protoheme IX farnesyltransferase activity [Evidence IEA]
GO:0006783 - heme biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150441.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589187.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927710.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150409.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149476.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150727.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151290.1
COORDINATES: similar to AA sequence:RefSeq:WP_014993486.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149936.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149559.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149916.1
COORDINATES: similar to AA sequence:RefSeq:WP_008734213.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151024.1
can carry out atp-dependent unwinding of double stranded rna. has a role in rna decay. involved in the rna degradosome, a multi-enzyme complex important in rna processing and messenger RNA degradation.
COORDINATES: similar to AA sequence:RefSeq:WP_007151607.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0003676 - nucleic acid binding [Evidence IEA]; GO:0003724 - RNA helicase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150169.1
GO:0004792 - thiosulfate sulfurtransferase activity [Evidence IEA]
COG: Opacity protein and related surface antigens
COORDINATES: similar to AA sequence:RefSeq:WP_007150249.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149691.1
Predicted ATPase related to phosphate starvation
COORDINATES: similar to AA sequence:RefSeq:WP_007151315.1
COORDINATES: similar to AA sequence:RefSeq:WP_014993477.1
isoprenylcysteine carboxylmethyltransferase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_014993476.1
YiiX/YebB-like N1pC/P60 family cysteine hydrolase
COORDINATES: similar to AA sequence:RefSeq:WP_008927727.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927728.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927729.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149461.1
endonuclease/exonuclease/phosphatase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_007150565.1
COORDINATES: similar to AA sequence:RefSeq:WP_008734194.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589213.1
GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; GO:1904047 - S-adenosyl-L-methionine binding [Evidence IEA]; GO:0016782 - transferase activity, transferring sulphur-containing groups [Evidence IEA]
tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB
COORDINATES: similar to AA sequence:RefSeq:WP_008927738.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589215.1
GO:0046872 - metal ion binding [Evidence IEA]; GO:0004540 - ribonuclease activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008927740.1
transporter associated domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_007150298.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151636.1
COORDINATES: similar to AA sequence:RefSeq:WP_014993460.1
GO:0042158 - lipoprotein biosynthetic process [Evidence IEA]; GO:0006497 - protein lipidation [Evidence IEA]
catalyses the hydrolysis of beta-lactams
COORDINATES: similar to AA sequence:RefSeq:WP_008927745.1
COORDINATES: similar to AA sequence:RefSeq:WP_007562671.1
COG: Sulfate permease and related transporters (MFS superfamily)
COORDINATES: similar to AA sequence:RefSeq:WP_008927747.1
GO:0008272 - sulfate transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008927748.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927749.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150223.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927751.1
GO:0004823 - leucine-tRNA ligase activity [Evidence IEA]
GO:0006429 - leucyl-tRNA aminoacylation [Evidence IEA]
speculated to be involved in cell duplication
COORDINATES: similar to AA sequence:RefSeq:WP_007151025.1
GO:0043165 - Gram-negative-bacterium-type cell outer membrane assembly [Evidence IEA]
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The delta subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA. Catalytic activity: n deoxynucleoside triphosphate = n diphosphate + {dna}(n).
COORDINATES: similar to AA sequence:RefSeq:WP_011589228.1
COORDINATES: similar to AA sequence:RefSeq:WP_014993450.1
catalyzes the nadph dependent reduction of l-gamma- glutamyl 5-phosphate into l-glutamate 5-semialdehyde and phosphate. the product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. l-glutamate 5-semialdehyde + phosphate + nadp(+) = l-gamma-glutamyl 5-phosphate + nadph.
COORDINATES: similar to AA sequence:RefSeq:WP_011589230.1
GO:0004350 - glutamate-5-semialdehyde dehydrogenase activity [Evidence IEA]; GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]
Nicotinic acid mononucleotide adenylyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_008927768.1
GO:0016779 - nucleotidyltransferase activity [Evidence IEA]
nicotinate-nucleotide adenylyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_007149530.1
GO:0043022 - ribosome binding [Evidence IEA]
GO:0017148 - negative regulation of translation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011589233.1
23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH
COORDINATES: similar to AA sequence:RefSeq:WP_007148473.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589235.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150193.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149344.1
GO:0016829 - lyase activity [Evidence IEA]
septal ring lytic transglycosylase RlpA family protein
D-Ala-D-Ala carboxypeptidase is involved in the metabolism of cell components
COORDINATES: similar to AA sequence:RefSeq:WP_011589238.1
D-alanyl-D-alanine carboxypeptidase family protein
acts on the D-isomers of alanine, leucine,aspartate, glutamate, aminobutyrate, norvaline and asparagine. D-alanine + 2-oxoglutarate = pyruvate + D-glutamate.
COORDINATES: similar to AA sequence:RefSeq:WP_007151142.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148441.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149699.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148533.1
GO:0033819 - lipoyl(octanoyl) transferase activity [Evidence IEA]
GO:0009249 - protein lipoylation [Evidence IEA]
synthesis of alpha-(+)-lipoic acid. it may be involved in the sulfur insertion chemistry in lipoate biosynthesis (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_011589243.1
GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; GO:0016992 - lipoate synthase activity [Evidence IEA]; GO:1904047 - S-adenosyl-L-methionine binding [Evidence IEA]
GO:0009107 - lipoate biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149455.1
GO:0004175 - endopeptidase activity [Evidence IEA]; GO:0009002 - serine-type D-Ala-D-Ala carboxypeptidase activity [Evidence IEA]
D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase
COORDINATES: similar to AA sequence:RefSeq:WP_007149421.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148675.1
involved in the tonB-dependent energy-dependent transport of unidentified receptor-bound substrates
COORDINATES: similar to AA sequence:RefSeq:WP_011589247.1
involved in the tonb-dependent energy-dependent transport of various receptor-bound substrates
COORDINATES: similar to AA sequence:RefSeq:WP_007150524.1
COORDINATES: similar to AA sequence:RefSeq:WP_014993426.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148840.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148405.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148455.1
reutilizes the intact tripeptide l-alanyl-gamma-d- glutamyl-meso-diaminopimelate by linking it to udp-n-acetylmuramic acid
COORDINATES: similar to AA sequence:RefSeq:WP_011589253.1
GO:0016881 - acid-amino acid ligase activity [Evidence IEA]
UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase
catalyzes the synthesis of macrocyclic lactones in anhydrous organic solvents
COORDINATES: similar to AA sequence:RefSeq:WP_007148500.1
seems to be acting in the folding of the extracellular lipase during its passage through the periplasm (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_007149910.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927796.1
hydrolyzes formamide with the production of ammonia which can be used as a source of nitrogen for growth. also acts, more slowly, on acetamide, propanamide and butanamide
COORDINATES: similar to AA sequence:RefSeq:WP_011589257.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151581.1
hydrolyse mid-chain aliphatic amides and which are coupled with nitrile hydratases to be involved in microbial nitrile metabolism (
COORDINATES: similar to AA sequence:RefSeq:WP_011589259.1
GO:0004040 - amidase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150617.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0033221 - ATPase-coupled urea transmembrane transporter activity [Evidence IEA]
GO:0015840 - urea transport [Evidence IEA]
urea ABC transporter ATP-binding subunit UrtE
component of the high-affinity branched-chain amino acid transport system.
COORDINATES: similar to AA sequence:RefSeq:WP_007148650.1
urea ABC transporter ATP-binding protein UrtD
COORDINATES: similar to AA sequence:RefSeq:WP_007148889.1
GO:0033221 - ATPase-coupled urea transmembrane transporter activity [Evidence IEA]
urea ABC transporter permease subunit UrtC
COORDINATES: similar to AA sequence:RefSeq:WP_011589263.1
urea ABC transporter permease subunit UrtB
COORDINATES: similar to AA sequence:RefSeq:WP_007149231.1
GO:0055052 - ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [Evidence IEA]; GO:0030288 - outer membrane-bounded periplasmic space [Evidence IEA]
GO:0033221 - ATPase-coupled urea transmembrane transporter activity [Evidence IEA]; GO:0033219 - urea binding [Evidence IEA]
urea ABC transporter substrate-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_007148655.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589266.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589267.1
Synthesis of fructose 1,6-bisphosphate from fructose 6-phosphate and MgATP
COORDINATES: similar to AA sequence:RefSeq:WP_007151519.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149001.1
COORDINATES: similar to AA sequence:RefSeq:WP_010321913.1
GO:0004845 - uracil phosphoribosyltransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_014992980.1
peptidoglycan-binding domain-containing protein
sulfurtransferase involved in cyanide detoxification.
COORDINATES: similar to AA sequence:RefSeq:WP_007150062.1
rhodanese-like domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_016913721.1
GO:0004427 - inorganic diphosphate phosphatase activity [Evidence IEA]
GO:0006796 - phosphate-containing compound metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148751.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930475.1
COORDINATES: protein motif:HMM:NF024880.2
COORDINATES: protein motif:HMM:NF018047.2
lipopolysaccharide kinase InaA family protein
COORDINATES: similar to AA sequence:RefSeq:WP_007149006.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930473.1
regulatory system: plays a role in the adaptation of the organism to the host environment
COORDINATES: similar to AA sequence:RefSeq:WP_009723304.1
presumably involved in the thiamine synthesis
COORDINATES: similar to AA sequence:RefSeq:WP_007019297.1
GO:0017013 - protein flavinylation [Evidence IEA]
COORDINATES: protein motif:HMM:NF023516.2
COORDINATES: similar to AA sequence:RefSeq:WP_008930469.1
required for disulfide bond formation in some periplasmic proteins. could also act as a disulfide oxidoreductase in cytochromes c biogenesis. the cysteines of apocytochromes c must be in the reduced state for covalent linkage between the two moieties to occur (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_008930468.1
required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. this transfer involves a cascade of disulfide bond formation and reduction steps (by similarity) .Catalytic activity: protein dithiol + nad(p)+ = protein disulfide + nad(p)h
COORDINATES: similar to AA sequence:RefSeq:WP_007149739.1
GO:0047134 - protein-disulfide reductase (NAD(P)) activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007151526.1
GO:0003855 - 3-dehydroquinate dehydratase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148313.1
acetyl-CoA carboxylase biotin carboxyl carrier protein
this protein is a component of the acetyl coenzyme a carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. atp + biotin-carboxyl-carrier protein + co(2) = adp + phosphate + carboxybiotin-carboxyl-carrier protein.
COORDINATES: similar to AA sequence:RefSeq:WP_014993381.1
GO:0003989 - acetyl-CoA carboxylase activity [Evidence IEA]; GO:0004075 - biotin carboxylase activity [Evidence IEA]
acetyl-CoA carboxylase biotin carboxylase subunit
COORDINATES: similar to AA sequence:RefSeq:WP_013795603.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150123.1
zinc-ribbon and DUF3426 domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_008930035.1
GO:0003824 - catalytic activity [Evidence IEA]; GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; GO:0016491 - oxidoreductase activity [Evidence IEA]; GO:0017150 - tRNA dihydrouridine synthase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008930034.1
DNA-binding transcriptional regulator Fis
bifunctional enzyme, catalysing the last two steps in de novo purine biosynthesis
COORDINATES: similar to AA sequence:RefSeq:WP_008734030.1
GO:0003824 - catalytic activity [Evidence IEA]; GO:0003937 - IMP cyclohydrolase activity [Evidence IEA]; GO:0004643 - phosphoribosylaminoimidazolecarboxamide formyltransferase activity [Evidence IEA]
GO:0006189 - 'de novo' IMP biosynthetic process [Evidence IEA]; GO:0006164 - purine nucleotide biosynthetic process [Evidence IEA]
bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
COORDINATES: similar to AA sequence:RefSeq:WP_008930032.1
GO:0004637 - phosphoribosylamine-glycine ligase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149417.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930030.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149888.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589299.1
GO:0004497 - monooxygenase activity [Evidence IEA]
2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone monooxygenase
decarboxylation of S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine. S-adenosyl-L-methionine = (5-deoxy-5-adenosyl)(3-aminopropyl) methylsulfonium salt + CO(2).
COORDINATES: similar to AA sequence:RefSeq:WP_007149942.1
GO:0004014 - adenosylmethionine decarboxylase activity [Evidence IEA]
GO:0008295 - spermidine biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008930025.1
COORDINATES: similar to AA sequence:RefSeq:WP_016506431.1
cAMP-activated global transcriptional regulator CRP
1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-(indol-3-yl)glycerol 3-phosphate + CO(2) + H(2)O.
COORDINATES: similar to AA sequence:RefSeq:WP_007148915.1
GO:0004425 - indole-3-glycerol-phosphate synthase activity [Evidence IEA]
GO:0006568 - tryptophan metabolic process [Evidence IEA]
indole-3-glycerol phosphate synthase TrpC
anthranilate + phosphoribosylpyrophosphate = N-5'-phosphoribosyl-anthranilate + diphosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_011589304.1
GO:0004048 - anthranilate phosphoribosyltransferase activity [Evidence IEA]
chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate. component 2 provides glutamine amidotransferase activity.
COORDINATES: similar to AA sequence:RefSeq:WP_007149974.1
aminodeoxychorismate/anthranilate synthase component II
chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate.
COORDINATES: similar to AA sequence:RefSeq:WP_014993362.1
GO:0004049 - anthranilate synthase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008928695.1
GO:0003824 - catalytic activity [Evidence IEA]; GO:0030151 - molybdenum ion binding [Evidence IEA]; GO:0030170 - pyridoxal phosphate binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149297.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149269.1
COORDINATES: similar to AA sequence:RefSeq:WP_008734489.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149853.1
COORDINATES: similar to AA sequence:RefSeq:WP_014993359.1
cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain
COORDINATES: similar to AA sequence:RefSeq:WP_008734496.1
GO:0009486 - cytochrome bo3 ubiquinol oxidase activity [Evidence IEA]
GO:0015990 - electron transport coupled proton transport [Evidence IEA]
cytochrome o ubiquinol oxidase subunit IV
COORDINATES: similar to AA sequence:RefSeq:WP_007150293.1
cytochrome o ubiquinol oxidase subunit III
COORDINATES: similar to AA sequence:RefSeq:WP_007149982.1
cytochrome o ubiquinol oxidase subunit I
cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain of e.coli that predominates when cells are grown at high aeration (by similarity)
COORDINATES: similar to AA sequence:RefSeq:WP_007149657.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150080.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589318.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149095.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928681.1
converts D-ribulose 5-phosphate into D-xylulose 5-phosphate in Calvin's reductive pentose phosphate cycle
COORDINATES: similar to AA sequence:RefSeq:WP_007151001.1
GO:0004750 - D-ribulose-phosphate 3-epimerase activity [Evidence IEA]
GO:0006098 - pentose-phosphate shunt [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149315.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148480.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589324.1
assist in the folding of extracytoplasmic proteins.
COORDINATES: similar to AA sequence:RefSeq:WP_011589325.1
catalyzes the condensation of 4-(phosphohydroxy)-L-threonine and 1-deoxy-D-xylulose, to form either pyridoxine (vitamin B6) or pyridoxine 5'-phosphate (PNP).
COORDINATES: similar to AA sequence:RefSeq:WP_007150855.1
GO:0050570 - 4-hydroxythreonine-4-phosphate dehydrogenase activity [Evidence IEA]
4-hydroxythreonine-4-phosphate dehydrogenase PdxA
responsible for the dimethylation of adenosines inribosomal RNAs.
COORDINATES: similar to AA sequence:RefSeq:WP_011589327.1
GO:0000179 - rRNA (adenine-N6,N6-)-dimethyltransferase activity [Evidence IEA]
16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA
COORDINATES: similar to AA sequence:RefSeq:WP_011589328.1
Diadenosine tetraphosphatase and related serine
COORDINATES: similar to AA sequence:RefSeq:WP_007150822.1
GO:0008803 - bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity [Evidence IEA]
symmetrical bis(5'-nucleosyl)-tetraphosphatase
COORDINATES: similar to AA sequence:RefSeq:WP_007151016.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589331.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0004810 - CCA tRNA nucleotidyltransferase activity [Evidence IEA]; GO:0003723 - RNA binding [Evidence IEA]
GO:0001680 - tRNA 3'-terminal CCA addition [Evidence IEA]
multifunctional CCA addition/repair protein
COORDINATES: similar to AA sequence:RefSeq:WP_007151453.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149469.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150145.1
catalyzes the attachment of pyrophosphate to 6-hydroxymethyl-7,8-dihydropterin to form 6-hydroxymethyl-7,8-dihydropteridine pyrophosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_007150764.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928661.1
GO:0004150 - dihydroneopterin aldolase activity [Evidence IEA]
GO:0006760 - folic acid-containing compound metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_014993331.1
GO:0008374 - O-acyltransferase activity [Evidence IEA]
GO:0006654 - phosphatidic acid biosynthetic process [Evidence IEA]
glycerol-3-phosphate 1-O-acyltransferase PlsY
proteolysis and peptidolysis; Main role: Protein fate; Subrole: Degradation of proteins, peptides,and glycopeptides.
COORDINATES: similar to AA sequence:RefSeq:WP_011589338.1
tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD
COORDINATES: similar to AA sequence:RefSeq:WP_011235429.1
COORDINATES: similar to AA sequence:RefSeq:WP_008733644.1
DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis.
COORDINATES: similar to AA sequence:RefSeq:WP_007150316.1
GO:0003896 - DNA primase activity [Evidence IEA]
GO:0006269 - DNA replication, synthesis of RNA primer [Evidence IEA]
The sigma factor is an initiation factor that promotes attachment of the RNA polymerase to specific initiation sites and then is released.
COORDINATES: similar to AA sequence:RefSeq:WP_011589341.1
GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; GO:0016987 - sigma factor activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007113607.1
plasmid mobilization relaxosome protein MobC
COORDINATES: protein motif:HMM:NF015397.2
relaxase/mobilization nuclease domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_017363018.1
COORDINATES: protein motif:HMM:NF019608.2
COORDINATES: protein motif:HMM:NF016491.2
COORDINATES: protein motif:HMM:NF013793.2
COORDINATES: protein motif:HMM:TIGR00180.1
GO:0007059 - chromosome segregation [Evidence IEA]; GO:0000910 - cytokinesis [Evidence IEA]
cell wall formation. synthesis of cross-linked peptidoglycan from the lipid intermediates.
COORDINATES: similar to AA sequence:RefSeq:WP_007149215.1
COORDINATES: protein motif:HMM:NF014177.2
GO:0003677 - DNA binding [Evidence IEA]; GO:0008170 - N-methyltransferase activity [Evidence IEA]
GO:0006306 - DNA methylation [Evidence IEA]
IS3-like element ISAbo1 family transposase
ankyrin repeat domain-containing protein
COORDINATES: protein motif:HMM:NF012242.2
COORDINATES: similar to AA sequence:RefSeq:WP_017430531.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151524.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589365.1
involved in the reduction of ferric iron in cytoplasmic ferrioxamine b
COORDINATES: similar to AA sequence:RefSeq:WP_007149058.1
GO:0051537 - 2 iron, 2 sulfur cluster binding [Evidence IEA]; GO:0008199 - ferric iron binding [Evidence IEA]; GO:0016491 - oxidoreductase activity [Evidence IEA]
GO:0033214 - siderophore-dependent iron import into cell [Evidence IEA]
catalyzes the hydroxylation of l-ornithine (l-orn)
COORDINATES: similar to AA sequence:RefSeq:WP_007148321.1
lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_007150381.1
ferrioxamine binding and uptake, in association with the tonb protein (by similarity). may play a role in intestinal colonization.
COORDINATES: similar to AA sequence:RefSeq:WP_007151461.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148467.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151409.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150051.1
GO:0140359 - ABC-type transporter activity [Evidence IEA]; GO:1904680 - peptide transmembrane transporter activity [Evidence IEA]
multidrug ABC transporter permease/ATP-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_008928646.1
It is thought to normally generate double strand breaks in DNA, except in the presence of high salt concentrations and RNA, when it generates single strand breaks in DNA
COORDINATES: similar to AA sequence:RefSeq:WP_007150057.1
GO:0004518 - nuclease activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150992.1
acyl-CoA dehydrogenase C-terminal domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_007149920.1
GO:0016639 - oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [Evidence IEA]
GO:0006520 - amino acid metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_014995204.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589380.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151538.1
outer membrane bound acyl hydrolase with a broad substrate specificity
COORDINATES: similar to AA sequence:RefSeq:WP_007149293.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589383.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927206.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150296.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150638.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589387.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151396.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927211.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150218.1
COORDINATES: similar to AA sequence:RefSeq:WP_008733016.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589392.1
histidine triad nucleotide-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_007151130.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589394.1
COORDINATES: similar to AA sequence:RefSeq:WP_014993266.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148767.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930323.1
GO:0071949 - FAD binding [Evidence IEA]; GO:0020037 - heme binding [Evidence IEA]; GO:0008941 - nitric oxide dioxygenase activity [Evidence IEA]; GO:0019825 - oxygen binding [Evidence IEA]
GO:0051409 - response to nitrosative stress [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008930322.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148972.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930315.1
COORDINATES: protein motif:HMM:NF012872.2
sulfite reductase flavoprotein subunit alpha
COORDINATES: protein motif:HMM:NF015425.2
COORDINATES: similar to AA sequence:RefSeq:WP_008930312.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930311.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930310.1
Members of this family catalyse the denitrification of a number of nitroalkanes using either FAD or FMN as a cofactor
COORDINATES: similar to AA sequence:RefSeq:WP_008930309.1
COORDINATES: similar to AA sequence:RefSeq:WP_016855355.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149115.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148453.1
atp + l-threonine + trna(thr) = amp + diphosphate + l-threonyl-trna(thr).
COORDINATES: similar to AA sequence:RefSeq:WP_007150842.1
GO:0004829 - threonine-tRNA ligase activity [Evidence IEA]
GO:0006435 - threonyl-tRNA aminoacylation [Evidence IEA]
1-(5-phosphoribosyl)-AMP + H(2)O = 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylidene amino]imidazole-4-carboxamide.
COORDINATES: similar to AA sequence:RefSeq:WP_007151476.1
GO:0004635 - phosphoribosyl-AMP cyclohydrolase activity [Evidence IEA]
atp + l-cysteine + trna(cys) = amp + diphosphate + l-cysteinyl-trna(cys).
COORDINATES: similar to AA sequence:RefSeq:WP_007151089.1
GO:0004817 - cysteine-tRNA ligase activity [Evidence IEA]
GO:0006423 - cysteinyl-tRNA aminoacylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148766.1
GO:0008289 - lipid binding [Evidence IEA]
COORDINATES: protein motif:HMM:NF013932.2
membrane protein insertion efficiency factor YidD
Outer membrane receptor proteins, mostly Fe transport
COORDINATES: similar to AA sequence:RefSeq:WP_007149830.1
COORDINATES: similar to AA sequence:RefSeq:WP_014993256.1
COORDINATES: protein motif:HMM:NF012791.2
COORDINATES: protein motif:HMM:NF012686.2
COORDINATES: similar to AA sequence:RefSeq:WP_008927234.1
GO:0003933 - GTP cyclohydrolase activity [Evidence IEA]
GO:0035998 - 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_014993254.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150947.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927237.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150973.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149076.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150912.1
GO:0033816 - diaminobutyrate acetyltransferase activity [Evidence IEA]
GO:0019491 - ectoine biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149054.1
GO:0045303 - diaminobutyrate-2-oxoglutarate transaminase activity [Evidence IEA]
diaminobutyrate--2-oxoglutarate transaminase
Cyclic condensation of gamma-n-acetyl-alpha,gamma- diaminobutyric acid (adaba) to ectoine. Pathway biosynthesis of ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid); last step.
COORDINATES: similar to AA sequence:RefSeq:WP_011589430.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149794.1
DcaP family trimeric outer membrane transporter
the n-terminal region is similar to that of other regulatory components of sensory transduction systems.
COORDINATES: similar to AA sequence:RefSeq:WP_007149538.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151386.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149272.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151184.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150452.1
putative nucleotidyltransferase substrate binding domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_011589436.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150358.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150105.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151444.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149734.1
catalyze a 1'4-condensation between 5 carbon isoprene units.
COORDINATES: similar to AA sequence:RefSeq:WP_007148545.1
catalyzes the acyloin condensation reaction between c atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-d-xylulose-5-phosphate (dxp). pyruvate + d-glyceraldehyde 3-phosphate = 1- deoxy-d-xylulose 5-phosphate + co(2).
COORDINATES: similar to AA sequence:RefSeq:WP_011589444.1
GO:0008661 - 1-deoxy-D-xylulose-5-phosphate synthase activity [Evidence IEA]
GO:0009240 - isopentenyl diphosphate biosynthetic process [Evidence IEA]; GO:0008615 - pyridoxine biosynthetic process [Evidence IEA]; GO:0009228 - thiamine biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148810.1
involved in the biosynthesis of phosphatidylglycerol
COORDINATES: similar to AA sequence:RefSeq:WP_007148510.1
GO:0008962 - phosphatidylglycerophosphatase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008927260.1
GO:0009030 - thiamine-phosphate kinase activity [Evidence IEA]
involved in the transcription termination process (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_011589448.1
transcription antitermination factor NusB
2 6,7-dimethyl-8-(1-d-ribityl)lumazine = riboflavin + 4-(1-d-ribitylamino)-5-amino-2,6-dihydroxypyrimidine
COORDINATES: similar to AA sequence:RefSeq:WP_007150362.1
GO:0009349 - riboflavin synthase complex [Evidence IEA]
GO:0000906 - 6,7-dimethyl-8-ribityllumazine synthase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011589450.1
GO:0008686 - 3,4-dihydroxy-2-butanone-4-phosphate synthase activity [Evidence IEA]; GO:0003935 - GTP cyclohydrolase II activity [Evidence IEA]
bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II
riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-d)- ribityl-amino-2,4(1h,3h)-pyrimidinedione and l-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. the alpha subunit catalyzes the dismutation of 6,7-dimethyl-8-lumazine to riboflavin and 5-amino-6-(1'-d)-ribityl-amino-2,4(1h,3h)- pyrimidinedione.
COORDINATES: similar to AA sequence:RefSeq:WP_008927264.1
converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
COORDINATES: similar to AA sequence:RefSeq:WP_007150480.1
GO:0008703 - 5-amino-6-(5-phosphoribosylamino)uracil reductase activity [Evidence IEA]; GO:0008835 - diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [Evidence IEA]
bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
COORDINATES: similar to AA sequence:RefSeq:WP_007148385.1
GO:0140110 - transcription regulator activity [Evidence IEA]
interconversion of serine and glycine. 5,10-methylenetetrahydrofolate + glycine + H(2)O = tetrahydrofolate + L-serine.
COORDINATES: similar to AA sequence:RefSeq:WP_011589454.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927273.1
GO:0045900 - negative regulation of translational elongation [Evidence IEA]
energy-dependent translational throttle protein EttA
COORDINATES: similar to AA sequence:RefSeq:WP_008927274.1
the sigma factor is an initiation factor that promotes attachment of the rna polymerase to specific initiation sites and then is released (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_011589457.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; GO:0016987 - sigma factor activity [Evidence IEA]
GO:0006352 - DNA-templated transcription initiation [Evidence IEA]; GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]
sigma-70 family RNA polymerase sigma factor
COORDINATES: similar to AA sequence:RefSeq:WP_008927276.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149415.1
COG: Methylase involved in ubiquinone/menaquinone biosynthesis
COORDINATES: similar to AA sequence:RefSeq:WP_014993168.1
resistance to hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. mera protein is responsible for volatilizing mercury as hg(0)
COORDINATES: similar to AA sequence:RefSeq:WP_007150636.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151341.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927281.1
provides the d-alanine required for cell wall biosynthesis (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_011589464.1
GO:0008784 - alanine racemase activity [Evidence IEA]
Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with dnaC protein,primase, and other prepriming proteins. subunit homohexamer.
COORDINATES: similar to AA sequence:RefSeq:WP_007150454.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589466.1
COORDINATES: similar to AA sequence:RefSeq:WP_012071134.1
pria recognizes a specific hairpin sequence on phix ssdna. this structure is then recognized and bound by proteins prib and pric. formation of the primosome proceeds with the subsequent actions of dnab, dnac, dnat and primase.
COORDINATES: similar to AA sequence:RefSeq:WP_011589467.1
Binds together with S18 to 16S ribosomal RNA.
COORDINATES: similar to AA sequence:RefSeq:WP_008927286.1
COORDINATES: similar to AA sequence:RefSeq:WP_016803977.1
GO:0009451 - RNA modification [Evidence IEA]
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB
COORDINATES: similar to AA sequence:RefSeq:WP_007148487.1
GO:0008997 - ribonuclease R activity [Evidence IEA]
GO:0006401 - RNA catabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149579.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927292.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927293.1
catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP
COORDINATES: similar to AA sequence:RefSeq:WP_011589474.1
GO:0004019 - adenylosuccinate synthase activity [Evidence IEA]; GO:0005525 - GTP binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149078.1
ATP phosphoribosyltransferase regulatory subunit
COORDINATES: similar to AA sequence:RefSeq:WP_014993143.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927305.1
GO:0045861 - negative regulation of proteolysis [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150679.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149377.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149110.1
catalyzes the first step in the biosynthesis of 2- methylthio-n6-(delta(2)-isopentenyl)-adenosine (ms[2]i[6]a]) adjacent to the anticodon of several trna species
COORDINATES: similar to AA sequence:RefSeq:WP_011589480.1
GO:0052381 - tRNA dimethylallyltransferase activity [Evidence IEA]
tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA
COORDINATES: similar to AA sequence:RefSeq:WP_007149053.1
GO:0032300 - mismatch repair complex [Evidence IEA]
GO:0005524 - ATP binding [Evidence IEA]; GO:0016887 - ATP hydrolysis activity [Evidence IEA]; GO:0030983 - mismatched DNA binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150228.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150034.1
tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE
COORDINATES: similar to AA sequence:RefSeq:WP_020683739.1
bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase
COORDINATES: similar to AA sequence:RefSeq:WP_007150323.1
GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; GO:0052693 - epoxyqueuosine reductase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011589486.1
GO:0000175 - 3'-5'-exoribonuclease activity [Evidence IEA]; GO:0003676 - nucleic acid binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011589487.1
small ribosomal subunit biogenesis GTPase RsgA
thiosulfate + cyanide = sulfite + thiocyanate.
COORDINATES: similar to AA sequence:RefSeq:WP_007151492.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589489.1
GO:0004609 - phosphatidylserine decarboxylase activity [Evidence IEA]
Phosphatidylserine decarboxylase is synthesized as a single chain precursor. Generation of the pyruvoyl active site from a Ser is coupled to cleavage of a Gly-Ser bond between the larger (beta) and smaller (alpha chains). It is an integral membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_007148887.1
transfer heptose to the lipopolysaccharide core
COORDINATES: similar to AA sequence:RefSeq:WP_008927898.1
atp + 7,8-diaminononanoate + co(2) = adp + phosphate + dethiobiotin
COORDINATES: similar to AA sequence:RefSeq:WP_007149762.1
GO:0004141 - dethiobiotin synthase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011589493.1
GO:0008171 - O-methyltransferase activity [Evidence IEA]
seems to be implicated in the early steps of biotin biosynthesis.
COORDINATES: similar to AA sequence:RefSeq:WP_008927453.1
catalytic activity 6-carboxyhexanoyl-coa + l-alanine = 8-amino-7- oxononanoate + coa + co(2)
COORDINATES: similar to AA sequence:RefSeq:WP_011589495.1
GO:0008710 - 8-amino-7-oxononanoate synthase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149089.1
GO:0051537 - 2 iron, 2 sulfur cluster binding [Evidence IEA]; GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; GO:0004076 - biotin synthase activity [Evidence IEA]; GO:1904047 - S-adenosyl-L-methionine binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007151284.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151499.1
COORDINATES: similar to AA sequence:RefSeq:WP_014996273.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927462.1
COORDINATES: similar to AA sequence:RefSeq:WP_010629010.1
GO:0008124 - 4-alpha-hydroxytetrahydrobiopterin dehydratase activity [Evidence IEA]
GO:0006729 - tetrahydrobiopterin biosynthetic process [Evidence IEA]
4a-hydroxytetrahydrobiopterin dehydratase
COORDINATES: similar to AA sequence:RefSeq:WP_014996275.1
catalyzes the sequential decarboxylation of the four acetyl side chains of uroporphyrinogen to yield coproporphyrinogen (uroporphyrinogen-iii = coproporphyrinogen + 4 co(2))
COORDINATES: similar to AA sequence:RefSeq:WP_007148451.1
GO:0004853 - uroporphyrinogen decarboxylase activity [Evidence IEA]
2 L-glutamate + NADP(+) = L-glutamine + 2-oxoglutarate + NADPH.
COORDINATES: similar to AA sequence:RefSeq:WP_014996277.1
gltB is a complex iron-sulfur flavoprotein that catalyzes the reductive transfer of L-glutamine amide group to the C(2) carbon of 2-oxoglutarate (2-OG) using either reduced pyridine nucleotides (NADH or NADPH) or reduced ferredoxin (Fd) as the physiological electron transfer system.
COORDINATES: similar to AA sequence:RefSeq:WP_007148743.1
GO:0003824 - catalytic activity [Evidence IEA]; GO:0015930 - glutamate synthase activity [Evidence IEA]; GO:0016491 - oxidoreductase activity [Evidence IEA]
GO:0006537 - glutamate biosynthetic process [Evidence IEA]; GO:0006807 - nitrogen compound metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149809.1
3-deoxy-arabino-heptulosonate 7-phosphate = 3-dehydroquinate + phosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_011589507.1
GO:0003856 - 3-dehydroquinate synthase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150995.1
COORDINATES: similar to AA sequence:RefSeq:WP_014996282.1
GO:0009297 - pilus assembly [Evidence IEA]; GO:0009306 - protein secretion [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_014996283.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150479.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148595.1
COORDINATES: similar to AA sequence:RefSeq:WP_020580661.1
cell wall formation. synthesis of cross-linked peptidoglycan from the lipid intermediates. the enzyme has a penicillin-insensitive transglycosylase n-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase c-terminal domain (cross-linking of the peptide subunits) (by similarity).
(s)-malate + nadp(+) = pyruvate + co(2) + nadph
COORDINATES: similar to AA sequence:RefSeq:WP_011589515.1
malic enzyme-like NAD(P)-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_007149307.1
Recognizes a specific hairpin sequence on phix ssDNA; this structure is then recognized and bound by proteins priB and priC. Formation of the primosome proceeds with the subsequent actions of dnaB, dnaC, dnaT and primase. priA then functions as a helicase within the primosome.
COORDINATES: similar to AA sequence:RefSeq:WP_007150102.1
atp + l-arginine + trna(arg) = amp + diphosphate + l-arginyl-trna(arg).
COORDINATES: similar to AA sequence:RefSeq:WP_011589518.1
GO:0004814 - arginine-tRNA ligase activity [Evidence IEA]
GO:0006420 - arginyl-tRNA aminoacylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148617.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150844.1
GO:0004298 - threonine-type endopeptidase activity [Evidence IEA]
GO:0051603 - proteolysis involved in protein catabolic process [Evidence IEA]
Chaperone subunit of a proteasome-like degradation complex. Subunit: a double ring-shaped homohexamer of hslV is capped on each side by a ring-shaped hslU homohexamer.
COORDINATES: similar to AA sequence:RefSeq:WP_011589520.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0016887 - ATP hydrolysis activity [Evidence IEA]; GO:0008233 - peptidase activity [Evidence IEA]
ATP-dependent protease ATPase subunit HslU
COORDINATES: similar to AA sequence:RefSeq:WP_007151135.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150919.1
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE
COORDINATES: similar to AA sequence:RefSeq:WP_007150828.1
SCP2 sterol-binding domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_007148615.1
1-(5-phosphoribosyl)-ATP + H(2)O = 1-(5-phosphoribosyl)-AMP + diphosphate
COORDINATES: similar to AA sequence:RefSeq:WP_011589524.1
GO:0004636 - phosphoribosyl-ATP diphosphatase activity [Evidence IEA]
required to correct localization of precursor proteins bearing signal peptides with the twin arginine conserved motif s/t-r-r-x-f-l-k. this sec-independent pathway is termed tat for twin-arginine translocation system. this system mainly transports proteins with bound cofactors that require folding prior to export (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_011589525.1
GO:0043953 - protein transport by the Tat complex [Evidence IEA]
Sec-independent protein translocase subunit TatA
COORDINATES: similar to AA sequence:RefSeq:WP_011589526.1
GO:0015628 - protein secretion by the type II secretion system [Evidence IEA]; GO:0015031 - protein transport [Evidence IEA]
Sec-independent protein translocase protein TatB
has a remarkable ability to transport folded proteins even enzyme complexes across the cytoplasmic membrane.
COORDINATES: similar to AA sequence:RefSeq:WP_007151253.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149716.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589529.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149498.1
ydrolyzes d-tyrosyl-trna(tyr) into d-tyrosine and free trna(tyr). could be a defense mechanism against a harmful effect of d-tyrosine (by similarity)
COORDINATES: similar to AA sequence:RefSeq:WP_011589531.1
specifically catalyzes the removal of n-terminal proline residues from peptides (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_007148842.1
GO:0004177 - aminopeptidase activity [Evidence IEA]
GO:0030163 - protein catabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150801.1
COORDINATES: similar to AA sequence:RefSeq:WP_014992989.1
GO:0016310 - phosphorylation [Evidence IEA]; GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]; GO:0007165 - signal transduction [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150214.1
ATP + L-glutamate + NH(3) = ADP + phosphate + L-glutamine.
COORDINATES: similar to AA sequence:RefSeq:WP_011589537.1
GO:0004356 - glutamate-ammonia ligase activity [Evidence IEA]
GO:0006542 - glutamine biosynthetic process [Evidence IEA]; GO:0006807 - nitrogen compound metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150166.1
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (EC: 2.1.1.61) catalyses the addition of 5-methylaminomethyl-2-thiouridylate to tRNAs using S-adenosyl-L-methionine as a substrate and releasing S-adenosyl-L-homocysteine. The enzyme is cytoplasmic and is involved in tRNA processing.
COORDINATES: similar to AA sequence:RefSeq:WP_011589539.1
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_008927507.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927508.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149821.1
inactive transglutaminase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_014992982.1
Predicted membrane GTPase involved in stress response
COORDINATES: similar to AA sequence:RefSeq:WP_011589544.1
GO:0006950 - response to stress [Evidence IEA]; GO:0006412 - translation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008927900.1
Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an RNA molecule.
COORDINATES: similar to AA sequence:RefSeq:WP_007149375.1
GO:0008175 - tRNA methyltransferase activity [Evidence IEA]
tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL
This is one of the proteins required for the normal export of envelope proteins out of the cell cytoplasm; it may be involved in the initiation of the exporting process, by binding to the nascent polypeptide via a signal sequence, maintaining a stable and pre-translocation conformation. Subunit. part of the prokaryotic protein translocation apparatus which comprise secA, secB, secD, secE, secF, secG and secY
COORDINATES: similar to AA sequence:RefSeq:WP_011589547.1
GO:0051262 - protein tetramerization [Evidence IEA]; GO:0015031 - protein transport [Evidence IEA]
It functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase.
COORDINATES: similar to AA sequence:RefSeq:WP_007150626.1
COORDINATES: similar to AA sequence:RefSeq:WP_014992976.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149700.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150938.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150907.1
divergent polysaccharide deacetylase family protein
catalyzes the conversion of prfar and glutamine to igp, aicar and glutamate. the hisf subunit catalyzes the cyclization activity that produces igp and aicar from prfar using the ammonia provided by the hish subunit. 5-[(5-phospho-1-deoxyribulos-1- ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4- carboxamide + L-glutamine = imidazole-glycerol phosphate + 5- aminoimidazol-4-carboxamide ribonucleotide + L-glutamate + H(2)O.
COORDINATES: similar to AA sequence:RefSeq:WP_011589553.1
GO:0000107 - imidazoleglycerol-phosphate synthase activity [Evidence IEA]
imidazole glycerol phosphate synthase subunit HisF
COORDINATES: similar to AA sequence:RefSeq:WP_035459508.1
GO:0003949 - 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase activity [Evidence IEA]
1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase
imidazole glycerol phosphate synthase catalyzes the conversion of prfar and glutamine to igp, aicar and glutamate. the hisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to hisF for the synthesis of igp and aicar. 5-[(5-phospho-1-deoxyribulos-1- ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4- carboxamide + L-glutamine = imidazole-glycerol phosphate + 5- aminoimidazol-4-carboxamide ribonucleotide + L-glutamate + H(2)O.
COORDINATES: similar to AA sequence:RefSeq:WP_007150969.1
GO:0016884 - carbon-nitrogen ligase activity, with glutamine as amido-N-donor [Evidence IEA]; GO:0000107 - imidazoleglycerol-phosphate synthase activity [Evidence IEA]
imidazole glycerol phosphate synthase subunit HisH
D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H(2)O.
COORDINATES: similar to AA sequence:RefSeq:WP_011589556.1
GO:0004424 - imidazoleglycerol-phosphate dehydratase activity [Evidence IEA]
imidazoleglycerol-phosphate dehydratase HisB
COORDINATES: similar to AA sequence:RefSeq:WP_008927915.1
member of the two-component regulatory system yycg/yycf involved in the regulation of the ftsaz operon
COORDINATES: similar to AA sequence:RefSeq:WP_007149266.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149063.1
Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past go lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8- oxoguanine.
COORDINATES: similar to AA sequence:RefSeq:WP_007150513.1
GO:0019104 - DNA N-glycosylase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149934.1
GO:0005506 - iron ion binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008930306.1
involved in the biosynthesis of the lipopolysaccharide (LPS) core component
COORDINATES: similar to AA sequence:RefSeq:WP_011589564.1
GO:0009058 - biosynthetic process [Evidence IEA]; GO:0005975 - carbohydrate metabolic process [Evidence IEA]
bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE
possibly involved in lpipolysaccharides (LPS) biosynthesis (by similarity to P. putida)
COORDINATES: similar to AA sequence:RefSeq:WP_007151619.1
transfers myristate or laurate during lipopolysaccharide core biosynthesis
COORDINATES: similar to AA sequence:RefSeq:WP_008927924.1
LpxL/LpxP family Kdo(2)-lipid IV(A) lauroyl/palmitoleoyl acyltransferase
possibly involved in biosyntheis of lipopolysaccharides (LPS)
COORDINATES: similar to AA sequence:RefSeq:WP_007149786.1
possibly involved in the biosynthesis of the lipopolysaccharides (LPS)
COORDINATES: similar to AA sequence:RefSeq:WP_007149928.1
addition of phosphate to O-4 of the first heptose residue of the lipopolysaccharide (LPS) inner core region.
COORDINATES: similar to AA sequence:RefSeq:WP_014993014.1
GO:0016301 - kinase activity [Evidence IEA]
lipopolysaccharide core heptose(I) kinase RfaP
Involved in the biosynthesis of the lipopolysaccharides (LPS) outer core
COORDINATES: similar to AA sequence:RefSeq:WP_014993013.1
involved in the biosynthesis of the lipopolysaccharides (LPS) inner core component by transferring the first (innermost) heptose to KDO
COORDINATES: similar to AA sequence:RefSeq:WP_007149321.1
GO:0008920 - lipopolysaccharide heptosyltransferase activity [Evidence IEA]
lipopolysaccharide heptosyltransferase I
involved in the biosynthesis of the lipopolysaccharides (LPS) by transferring the second heptose to the LPS outer core
COORDINATES: similar to AA sequence:RefSeq:WP_007149264.1
lipopolysaccharide heptosyltransferase II
acts on leucine, isoleucine and valine. L-leucine + 2-oxoglutarate = 4-methyl-2- oxopentanoate + L-glutamate.
COORDINATES: similar to AA sequence:RefSeq:WP_020410671.1
GO:0004084 - branched-chain-amino-acid transaminase activity [Evidence IEA]
GO:0009081 - branched-chain amino acid metabolic process [Evidence IEA]
Glutamine synthetase adenylyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_007149467.1
GO:0008882 - [glutamate-ammonia-ligase] adenylyltransferase activity [Evidence IEA]
bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase
involved in a general secretion pathway (gsp) for the export of proteins. required for the translocation of pectate lyases and cellulases across the outer membrane
COORDINATES: similar to AA sequence:RefSeq:WP_007149473.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150518.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927940.1
acetyl-CoA + L-glutamate = CoA + N-acetyl-L-glutamate.
COORDINATES: similar to AA sequence:RefSeq:WP_011589580.1
GO:0004042 - acetyl-CoA:L-glutamate N-acetyltransferase activity [Evidence IEA]
COORDINATES: protein motif:HMM:NF019313.2
COORDINATES: similar to AA sequence:RefSeq:WP_013796795.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150779.1
2-hydroxychromene-2-carboxylate isomerase (hcca isomerase).
COORDINATES: similar to AA sequence:RefSeq:WP_007150317.1
GO:0015035 - protein-disulfide reductase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007151160.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927947.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927948.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151400.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150136.1
ABC-type transport auxiliary lipoprotein family protein
Uncharacterized enzyme of heme biosynthesis, presumably involved in a late step of protoheme ix synthesis
COORDINATES: similar to AA sequence:RefSeq:WP_011589593.1
heme biosynthesis HemY N-terminal domain-containing protein
Uncharacterized enzyme of heme biosynthesis
COORDINATES: similar to AA sequence:RefSeq:WP_007149436.1
uroporphyrinogen-III C-methyltransferase
catalyses the reaction: Hydroxymethylbilane <=> uroporphyrinogen-III + H(2)O, by sequence similarity
COORDINATES: similar to AA sequence:RefSeq:WP_007148659.1
4 porphobilinogen + h(2)o = hydroxymethylbilane + 4 nh(3)
COORDINATES: similar to AA sequence:RefSeq:WP_007148739.1
GO:0004418 - hydroxymethylbilane synthase activity [Evidence IEA]
Response regulator of the LytR/AlgR family
COORDINATES: similar to AA sequence:RefSeq:WP_007148361.1
LytTR family DNA-binding domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_007151031.1
N-(L-arginino)succinate = fumarate + L-arginine.
COORDINATES: similar to AA sequence:RefSeq:WP_011589599.1
GO:0004056 - argininosuccinate lyase activity [Evidence IEA]
rnk can functionally replace alginate regulatory gene algr2.
COORDINATES: similar to AA sequence:RefSeq:WP_007151479.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150991.1
meso-2,6-diaminoheptanedioate = L-lysine + CO(2).
COORDINATES: similar to AA sequence:RefSeq:WP_008927960.1
GO:0008836 - diaminopimelate decarboxylase activity [Evidence IEA]
involved in ph homeostasis and sodium extrusion
COORDINATES: protein motif:HMM:TIGR00931.1
GO:1902600 - proton transmembrane transport [Evidence IEA]; GO:0006814 - sodium ion transport [Evidence IEA]
Acetyl-CoA + an alkane-alpha,omega-diamine = CoA + an N-acetyldiamine
COORDINATES: similar to AA sequence:RefSeq:WP_013795839.1
COORDINATES: similar to AA sequence:RefSeq:WP_014996339.1
GO:0008649 - rRNA methyltransferase activity [Evidence IEA]
GO:0070475 - rRNA base methylation [Evidence IEA]
23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ
COORDINATES: similar to AA sequence:RefSeq:WP_011589606.1
GO:0008837 - diaminopimelate epimerase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011589607.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589608.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150405.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927967.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927969.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149677.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927971.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149912.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927973.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150507.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927975.1
GO:0004799 - thymidylate synthase activity [Evidence IEA]
GO:0006231 - dTMP biosynthetic process [Evidence IEA]
Transfers the n-acyl diglyceride group on what will become the n-terminal cysteine of membrane lipoproteins.
COORDINATES: similar to AA sequence:RefSeq:WP_007151107.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149576.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150270.1
Signal transduction protein containing GAF and PtsI domains
COORDINATES: similar to AA sequence:RefSeq:WP_007149409.1
phosphoenolpyruvate--protein phosphotransferase
COORDINATES: similar to AA sequence:RefSeq:WP_014992829.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149961.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150783.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150345.1
Involved in copper efflux. Catalytic activity: ATP + h(2)o + cu(2+)(in) = ADP + phosphate + cu(2+)(out).
COORDINATES: similar to AA sequence:RefSeq:WP_013333609.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149243.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150319.1
COORDINATES: similar to AA sequence:RefSeq:WP_005819327.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149724.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148714.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927991.1
Required for the copper-inducible expression of copper resistance.
COORDINATES: similar to AA sequence:RefSeq:WP_007150418.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149238.1
GO:0004089 - carbonate dehydratase activity [Evidence IEA]; GO:0008270 - zinc ion binding [Evidence IEA]
GO:0015976 - carbon utilization [Evidence IEA]
function together with moac, is involved in the conversion of a guanosine derivative (gxp) into molybdopterin precursor z (by similarity)
COORDINATES: similar to AA sequence:RefSeq:WP_007148787.1
GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]
accelerate the folding of proteins (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_007111084.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149638.1
GO:0008881 - glutamate racemase activity [Evidence IEA]
catalyzes amidations at positions b, d, e, and g on adenosylcobyrinic a,c-diamide
COORDINATES: similar to AA sequence:RefSeq:WP_011589639.1
atp + cob(i)alamin + h(2)o = phosphate + diphosphate + adenosylcobalamin.
COORDINATES: similar to AA sequence:RefSeq:WP_009099725.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150981.1
GO:0042242 - cobyrinic acid a,c-diamide synthase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011589642.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928004.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149541.1
Outer membrane cobalamin receptor protein
COORDINATES: similar to AA sequence:RefSeq:WP_009099713.1
COORDINATES: nucleotide motif:Rfam:14.4:RF00174
cobalamin riboswitch; Derived by automated computational analysis using gene prediction method: cmsearch.
COORDINATES: protein motif:HMM:TIGR04052.1
metallo-mystery pair system four-Cys motif protein
2 ferrocytochrome c + h(2)o(2) = 2 ferricytochrome c + 2 h(2)o.
COORDINATES: protein motif:HMM:TIGR04039.1
catalyzes the late steps in adenosylcobalamin biosynthesis, which define the nucleotide loop assembly pathway.
COORDINATES: similar to AA sequence:RefSeq:WP_007150693.1
GO:0048472 - threonine-phosphate decarboxylase activity [Evidence IEA]
involved in the conversion of cobyric acid to cobinamide. addition of aminopropanol on the f carboxylic group
COORDINATES: similar to AA sequence:RefSeq:WP_007150539.1
GO:0016880 - acid-ammonia (or amide) ligase activity [Evidence IEA]
adenosylcobinamide-phosphate synthase CbiB
COORDINATES: similar to AA sequence:RefSeq:WP_007151531.1
GO:0008939 - nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity [Evidence IEA]
nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_007149990.1
atp-dependent phosphorylation of adenosylcobinamide and adds gmp to adenosylcobinamide phosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_007151301.1
GO:0043752 - adenosylcobinamide kinase activity [Evidence IEA]; GO:0000166 - nucleotide binding [Evidence IEA]
bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase
genes involved in alkylphosphonate uptake
COORDINATES: similar to AA sequence:RefSeq:WP_007149648.1
involved in the biosynthesis of a demolybdo-cofactor (molybdopterin), necessary for molybdo-enzymes. seems to be involved in a step of activation of molybdenum in the form of thiomolybdenum (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_007149978.1
involved in the biosynthesis of molybdopterin precursor z from guanosine
COORDINATES: similar to AA sequence:RefSeq:WP_007151564.1
molybdenum cofactor biosynthesis protein B
oxidative degradation of various compounds
COORDINATES: similar to AA sequence:RefSeq:WP_008928014.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151096.1
hydrolyzes a broad-spectrum of beta-lactams
COORDINATES: similar to AA sequence:RefSeq:WP_007148722.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148918.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150719.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148387.1
COORDINATES: similar to AA sequence:RefSeq:WP_009832963.1
secondary thiamine-phosphate synthase enzyme YjbQ
converts hydroxypyruvate to glycerate ((r)-glycerate + nad(+) = hydroxypyruvate + nadh)
COORDINATES: similar to AA sequence:RefSeq:WP_007148578.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589666.1
cofactor and FAD prosthetic group, these microsomal proteins catalyse the oxygenation of nucleophilic nitrogen, sulphur, phosphorous and selenium atoms in a range of structurally diverse compounds.
COORDINATES: similar to AA sequence:RefSeq:WP_007149016.1
Catalysis of oxidation-reduction (redox) reactions
COORDINATES: similar to AA sequence:RefSeq:WP_007150650.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151437.1
this protein seems to be a 2fe-2s ferredoxin.this dioxygenase system consists of four proteins: the two subunits of the hydroxylase component (bpha1 and bpha2), a ferredoxin (bpha3) and a ferredoxin reductase (bpha4).
COORDINATES: similar to AA sequence:RefSeq:WP_007151020.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150811.1
GO:0008792 - arginine decarboxylase activity [Evidence IEA]
GO:0006527 - arginine catabolic process [Evidence IEA]
S-adenosylmethioninamine + putrescine = 5'-methylthioadenosine + spermidine.
COORDINATES: similar to AA sequence:RefSeq:WP_007149545.1
COORDINATES: protein motif:HMM:NF013488.2
control the expression of genes associated with the biosynthesis of cysteine in bacteria.
COORDINATES: similar to AA sequence:RefSeq:WP_007149367.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589677.1
Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis.
COORDINATES: similar to AA sequence:RefSeq:WP_008929810.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150537.1
COORDINATES: protein motif:HMM:NF016301.2
COORDINATES: similar to AA sequence:RefSeq:WP_007149361.1
. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.
COORDINATES: similar to AA sequence:RefSeq:WP_007150284.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150710.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149884.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149525.1
not known; may be involved in recombination (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_007149044.1
catalyzes the nadph-dependent reduction of 3-deoxyglucosone (3-dg)
COORDINATES: similar to AA sequence:RefSeq:WP_007148509.1
1-haloalkane + h(2)o = a primary alcohol + halide.
COORDINATES: similar to AA sequence:RefSeq:WP_008929824.1
COORDINATES: similar to AA sequence:RefSeq:WP_007020020.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150042.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149094.1
conversion of an alcohol to acetaldehyde
COORDINATES: similar to AA sequence:RefSeq:WP_011589693.1
GO:0046872 - metal ion binding [Evidence IEA]; GO:0016491 - oxidoreductase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_005407314.1
type 1 glutamine amidotransferase domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_007149179.1
cytochrome d ubiquinol oxidase subunit II
ubiquinol-8 + o(2) = ubiquinone-8 + h(2)o
COORDINATES: similar to AA sequence:RefSeq:WP_008929829.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150058.1
growth-supporting role in biodegradative metabolism: epoxide ring opening and tetrachlorohydroquinone reductive dehalogenation are two examples of the reactions catalysed by these bacterial GSTs
COORDINATES: similar to AA sequence:RefSeq:WP_007149184.1
glutathione-dependent disulfide-bond oxidoreductase
COORDINATES: similar to AA sequence:RefSeq:WP_007148953.1
LysR substrate binding domain, by sequence similarity
COORDINATES: similar to AA sequence:RefSeq:WP_007149496.1
Glo 1 catalyzes the first step of the glyoxal pathway. S-lactoylglutathione is then converted by Glo 2 to lactic acid.
COORDINATES: similar to AA sequence:RefSeq:WP_007150956.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149947.1
Serves to protect the cell against DNA damage by alkyl hydroperoxides. It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the ahpC protein.
COORDINATES: similar to AA sequence:RefSeq:WP_007151522.1
GO:0016668 - oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor [Evidence IEA]
GO:0009398 - FMN biosynthetic process [Evidence IEA]; GO:0006805 - xenobiotic metabolic process [Evidence IEA]
Directly reduces organic hydroperoxides in its reduced dithiol form.
COORDINATES: similar to AA sequence:RefSeq:WP_003858764.1
GO:0102039 - NADH-dependent peroxiredoxin activity [Evidence IEA]
GO:0006979 - response to oxidative stress [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150400.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151597.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589708.1
GO:0016020 - membrane [Evidence IEA]; GO:0009274 - peptidoglycan-based cell wall [Evidence IEA]
monofunctional biosynthetic peptidoglycan transglycosylase
COORDINATES: similar to AA sequence:RefSeq:WP_007150206.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927893.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589711.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150584.1
Lrp/AsnC family transcriptional regulator
COORDINATES: similar to AA sequence:RefSeq:WP_016914275.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150979.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927321.1
phosphoserine + H(2)O = serine + phosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_007149710.1
GO:0036424 - L-phosphoserine phosphatase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148527.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150068.1
COORDINATES: similar to AA sequence:RefSeq:WP_014993056.1
GO:0072581 - protein-N6-(L-lysyl)-L-lysine modification to protein-N6-(beta-lysyl)-L-lysine [Evidence IEA]
involved in peptide bond synthesis. stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70s ribosomes in vitro. probably functions indirectly by altering the affinity of the ribosome for aminoacyl-trna, thus increasing their reactivity as acceptors for peptidyl transferase.
COORDINATES: similar to AA sequence:RefSeq:WP_007150421.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927327.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0004824 - lysine-tRNA ligase activity [Evidence IEA]; GO:0000166 - nucleotide binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007151493.1
catalyze the formation of hydroxil groups in organic compounds
COORDINATES: similar to AA sequence:RefSeq:WP_007148804.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927336.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927337.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150179.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150531.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927342.1
COORDINATES: similar to AA sequence:RefSeq:WP_014996349.1
necessary for efficient rna polymerase transcription elongation past template-encoded arresting sites. the arresting sites in dna have the property of trapping a certain fraction of elongating rna polymerases that pass through, resulting in locked ternary complexes. cleavage of the nascent transcript by cleavage factors such as grea or greb allows the resumption of elongation from the new 3'terminus. greb releases sequences of up to 9 nucleotides in length (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_014996350.1
catalyze the incorporation of oxygen of O2 into organic compounds
COORDINATES: similar to AA sequence:RefSeq:WP_011589732.1
2 5-aminolevulinate = porphobilinogen + 2 h(2)o
COORDINATES: similar to AA sequence:RefSeq:WP_008927346.1
GO:0003824 - catalytic activity [Evidence IEA]; GO:0046872 - metal ion binding [Evidence IEA]; GO:0004655 - porphobilinogen synthase activity [Evidence IEA]
GO:0033014 - tetrapyrrole biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007151368.1
GO:0009358 - polyphosphate kinase complex [Evidence IEA]
GO:0008976 - polyphosphate kinase activity [Evidence IEA]
GO:0006799 - polyphosphate biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011589735.1
GO:0004309 - exopolyphosphatase activity [Evidence IEA]; GO:0000287 - magnesium ion binding [Evidence IEA]
GO:0006798 - polyphosphate catabolic process [Evidence IEA]
participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions
COORDINATES: similar to AA sequence:RefSeq:WP_008927350.1
GO:0006662 - glycerol ether metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_017845130.1
GO:0008186 - ATP-dependent activity, acting on RNA [Evidence IEA]; GO:0004386 - helicase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150632.1
GO:0016831 - carboxy-lyase activity [Evidence IEA]
4-hydroxy-3-polyprenylbenzoate decarboxylase
COORDINATES: similar to AA sequence:RefSeq:WP_007150567.1
GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; GO:0016491 - oxidoreductase activity [Evidence IEA]
COORDINATES: protein motif:HMM:NF013345.2
involved in the transposition of the insertion sequence.
COORDINATES: similar to AA sequence:RefSeq:WP_076612056.1
COORDINATES: similar to AA sequence:RefSeq:WP_008958449.1
metal/formaldehyde-sensitive transcriptional repressor
Increase tolerance to divalent metal ions such as cadmium, zinc, and cobalt. These proteins are considered to be efflux pumps that remove these ions from cells, however others are implicated in ion uptake.
COORDINATES: similar to AA sequence:RefSeq:WP_008958448.1
CDF family Co(II)/Ni(II) efflux transporter DmeF
COORDINATES: similar to AA sequence:RefSeq:WP_007149189.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589745.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929048.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149865.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589743.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589750.1
manganese efflux pump MntP family protein
COORDINATES: nucleotide motif:Rfam:14.4:RF00080
yybP-ykoY riboswitch is a manganese riboswitch that directly binds Mn; Derived by automated computational analysis using gene prediction method: cmsearch.
COORDINATES: similar to AA sequence:RefSeq:WP_007150314.1
NirD/YgiW/YdeI family stress tolerance protein
COORDINATES: similar to AA sequence:RefSeq:WP_007149620.1
Catalysis of the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + ammonia.
COORDINATES: similar to AA sequence:RefSeq:WP_007150570.1
an alcohol + nad(+) = an aldehyde or ketone + nadh.
COORDINATES: similar to AA sequence:RefSeq:WP_007148404.1
zinc-binding alcohol dehydrogenase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_007149570.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589757.1
COORDINATES: protein motif:HMM:NF019335.2
incomplete; partial in the middle of a contig; missing C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
TonB-dependent receptor plug domain-containing protein
eceptor for the siderophore, ferripyoverdine.
COORDINATES: similar to AA sequence:RefSeq:WP_008927366.1
S1-like domain-containing RNA-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_007149191.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589762.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149379.1
TIGR04219 family outer membrane beta-barrel protein
COORDINATES: similar to AA sequence:RefSeq:WP_008738763.1
Topoisomerase IV is essential for chromosome segregation. It has relaxation of supercoiled DNA activity. Performs the decatenation events required during the replication of a circular DNA molecule. Subunit composed of two subunits: parC and parE.
COORDINATES: similar to AA sequence:RefSeq:WP_007148975.1
GO:0009340 - DNA topoisomerase IV complex [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148567.1
COORDINATES: similar to AA sequence:RefSeq:WP_008739328.1
YqiA/YcfP family alpha/beta fold hydrolase
COORDINATES: similar to AA sequence:RefSeq:WP_014993032.1
GO:0004115 - 3',5'-cyclic-AMP phosphodiesterase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008927378.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150975.1
required for the synthesis of the hydromethylpyrimidine (hmp) moiety of thiamine (4-amino-2-methyl-5- hydroxymethylpyrimidine)
COORDINATES: similar to AA sequence:RefSeq:WP_007148568.1
required for proper expression of outer membrane protein genes such as ompf, nmpc, protein 2,hemolysin, colicin v, or colicin e1. may be specialized for signal sequence independent, extracellular secretion in gram-negative bacteria.
COORDINATES: similar to AA sequence:RefSeq:WP_007150139.1
Involved in the biosynthesis of the essential lipopolysaccharide (LPS) component lipd A by transferring of 3-deoxy-D-mono octulonic acid (KDO) from CMP-KDO to a tetraacyldisaccharide 1,4'-bisphosphate precursor of lipid A (lipid IVa). Transfers a single molecule of KDO to lipid IVa.
COORDINATES: similar to AA sequence:RefSeq:WP_007149402.1
lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase
COORDINATES: similar to AA sequence:RefSeq:WP_011589774.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149502.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150832.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151441.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150243.1
GO:0004039 - allophanate hydrolase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007151420.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149173.1
COORDINATES: similar to AA sequence:RefSeq:WP_008927401.1
COORDINATES: similar to AA sequence:RefSeq:WP_015488659.1
Probable involved in the transport of branched chain amino acids
COORDINATES: similar to AA sequence:RefSeq:WP_007149175.1
component of the amino acid transport system.
COORDINATES: similar to AA sequence:RefSeq:WP_018916904.1
COORDINATES: similar to AA sequence:RefSeq:WP_013795613.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151325.1
bile acid:sodium symporter family protein
COORDINATES: protein motif:HMM:TIGR04534.1
COORDINATES: protein motif:HMM:NF014567.2
COORDINATES: protein motif:HMM:NF012301.2
COORDINATES: similar to AA sequence:RefSeq:WP_007148624.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589792.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929043.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929625.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148974.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150257.1
COORDINATES: protein motif:HMM:NF023390.2
could function in transcriptional regulation of sigma-54 dependent operons in conjunction with the npr (ptso) and iia-ntr (ptsn) proteins thereby providing a link between carbon and nitrogen assimilatory pathways. phosphoenolpyruvate + protein l-histidine = pyruvate + protein n(pi)-phospho-l-histidine.
COORDINATES: similar to AA sequence:RefSeq:WP_008929633.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149597.1
class I SAM-dependent rRNA methyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_007149858.1
COORDINATES: similar to AA sequence:RefSeq:NP_253975.1
GO:0030234 - enzyme regulator activity [Evidence IEA]
GO:0006808 - regulation of nitrogen utilization [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008732969.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149704.1
YifB family Mg chelatase-like AAA ATPase
COORDINATES: similar to AA sequence:RefSeq:WP_008929585.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150216.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929587.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149546.1
Formation of pseudouridine from uracil-516 in 16S ribosomal RNA (by similarity). Catalytic activity: uracil + d-ribose 5-phosphate = pseudouridine 5'-phosphate + h(2)o.
COORDINATES: similar to AA sequence:RefSeq:WP_020580434.1
Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.
COORDINATES: similar to AA sequence:RefSeq:WP_007148735.1
this is a monoheme c-type cytochrome. It is unreactive with cytochrome c reductase or oxidase but seems to function as an intermediate in nitrate respiration.
COORDINATES: similar to AA sequence:RefSeq:WP_008929593.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149004.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151427.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929596.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148755.1
Membrane transporters of cations and cationic drugs
COORDINATES: similar to AA sequence:RefSeq:WP_011589815.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149931.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148442.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151621.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148470.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151246.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148461.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149500.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148344.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149506.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149129.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149946.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151541.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150312.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150660.1
COORDINATES: similar to AA sequence:RefSeq:WP_008736113.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149676.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151586.1
GO:0052913 - 16S rRNA (guanine(966)-N(2))-methyltransferase activity [Evidence IEA]
16S rRNA (guanine(966)-N(2))-methyltransferase RsmD
COORDINATES: similar to AA sequence:RefSeq:WP_007148849.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148942.1
Functional homolog of srp receptor. Probably involved in the reception and insertion of a subset of proteins at the cytoplasmic membrane.
COORDINATES: similar to AA sequence:RefSeq:WP_007149048.1
GO:0003924 - GTPase activity [Evidence IEA]; GO:0005047 - signal recognition particle binding [Evidence IEA]
signal recognition particle-docking protein FtsY
is coded in an operon essential for cell division.
COORDINATES: similar to AA sequence:RefSeq:WP_007150059.1
GO:0000910 - cytokinesis [Evidence IEA]; GO:0006810 - transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150536.1
permease-like cell division protein FtsX
COORDINATES: similar to AA sequence:RefSeq:WP_007149640.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151521.1
Sulfur transfer protein involved in thiamine biosynthesis
COORDINATES: similar to AA sequence:RefSeq:WP_011589842.1
Uncharacterized enzyme of thiazole biosynthesis
COORDINATES: similar to AA sequence:RefSeq:WP_007149119.1
probably involved in the transfer of one-carbon groups
COORDINATES: similar to AA sequence:RefSeq:WP_011589844.1
GO:0008176 - tRNA (guanine-N7-)-methyltransferase activity [Evidence IEA]
tRNA (guanosine(46)-N7)-methyltransferase TrmB
COORDINATES: similar to AA sequence:RefSeq:WP_008929023.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929022.1
acetyl-CoA + L-homoserine = CoA + O-acetyl-L-homoserine.
COORDINATES: similar to AA sequence:RefSeq:WP_007148434.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150760.1
HAM1 protein protects the cell from 6-N-hydroxylaminopurine (HAP), either on the level of deoxynucleoside triphosphate or the DNA level by a yet unidentified set of reactions
COORDINATES: similar to AA sequence:RefSeq:WP_014992589.1
RdgB/HAM1 family non-canonical purine NTP pyrophosphatase
COORDINATES: similar to AA sequence:RefSeq:WP_007149403.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151469.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151497.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148517.1
This enzyme may play a significant role in processes leading to recovery from mutagenesis and/or cell death by alkylating agents. Also involved in the go system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8- oxoguanine = 7-oxog) from DNA. Can also nick DNA at apurinic/apyrimidinic sites (ap sites). Catalytic activity: hydrolysis of DNA containing ring-opened n(7)- methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(n- methyl)formamidopyrimide.
COORDINATES: similar to AA sequence:RefSeq:WP_007148506.1
GO:0003684 - damaged DNA binding [Evidence IEA]; GO:0019104 - DNA N-glycosylase activity [Evidence IEA]; GO:0003906 - DNA-(apurinic or apyrimidinic site) endonuclease activity [Evidence IEA]; GO:0016799 - hydrolase activity, hydrolyzing N-glycosyl compounds [Evidence IEA]; GO:0003676 - nucleic acid binding [Evidence IEA]; GO:0008534 - oxidized purine nucleobase lesion DNA N-glycosylase activity [Evidence IEA]; GO:0008270 - zinc ion binding [Evidence IEA]
GO:0006284 - base-excision repair [Evidence IEA]; GO:0006281 - DNA repair [Evidence IEA]
bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase
hyuA and hyuB convert D-and L-substituted hydantoins to corresponding N-carbamyl-amino acids.
COORDINATES: similar to AA sequence:RefSeq:WP_007148401.1
hydantoinase/oxoprolinase family protein
catalyzes the first reaction of fatty acid desaturation
COORDINATES: similar to AA sequence:RefSeq:WP_007148709.1
COORDINATES: protein motif:HMM:NF022495.2
COORDINATES: protein motif:HMM:NF013933.2
COORDINATES: similar to AA sequence:RefSeq:YP_005221021.1
the glycine cleavage system catalyzes the degradation of glycine. the P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. glycine + lipoylprotein = S-aminomethyldihydrolipoylprotein + CO(2).
COORDINATES: similar to AA sequence:RefSeq:WP_007150901.1
GO:0004375 - glycine dehydrogenase (decarboxylating) activity [Evidence IEA]
GO:0006546 - glycine catabolic process [Evidence IEA]
aminomethyl-transferring glycine dehydrogenase subunit GcvPB
COORDINATES: similar to AA sequence:RefSeq:WP_011589863.1
aminomethyl-transferring glycine dehydrogenase subunit GcvPA
the glycine cleavage system catalyzes the degradation of glycine. the H protein shuttles the methylamine group of glycine from the P protein to the T protein.
COORDINATES: similar to AA sequence:RefSeq:WP_011589864.1
GO:0019464 - glycine decarboxylation via glycine cleavage system [Evidence IEA]
the glycine cleavage system catalyzes the degradation of glycine. (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH(3) + dihydrolipoylprotein.
COORDINATES: similar to AA sequence:RefSeq:WP_011589865.1
GO:0004047 - aminomethyltransferase activity [Evidence IEA]
glycine cleavage system aminomethyltransferase GcvT
COORDINATES: similar to AA sequence:RefSeq:WP_007150101.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150382.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148808.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151363.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149956.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150336.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589872.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148702.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149380.1
COORDINATES: nucleotide motif:Rfam:14.4:RF00013
catalyses the interchange of 5-formyltetrahydrofolate (5-FTHF) to 5-10-methenyltetrahydrofolate
COORDINATES: similar to AA sequence:RefSeq:WP_007149088.1
GO:0030272 - 5-formyltetrahydrofolate cyclo-ligase activity [Evidence IEA]
GO:0006730 - one-carbon metabolic process [Evidence IEA]
catalyzes the formation of alpha-ketobutyrate from threonine in a two-step reaction. the first step is a dehydration of threonine, followed by rehydration and liberation of ammonia. L-threonine = 2-oxobutanoate + NH(3).
COORDINATES: similar to AA sequence:RefSeq:WP_011589876.1
GO:0004794 - L-threonine ammonia-lyase activity [Evidence IEA]
GO:0009097 - isoleucine biosynthetic process [Evidence IEA]
Ribose-5-phosphate isomerase interconverts ribose-5-phosphate and ribulose-5-phosphate. This enzyme plays essential roles in carbohydrate anabolism and catabolism.
COORDINATES: similar to AA sequence:RefSeq:WP_011589877.1
GO:0004751 - ribose-5-phosphate isomerase activity [Evidence IEA]
GO:0009052 - pentose-phosphate shunt, non-oxidative branch [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149731.1
COORDINATES: similar to AA sequence:RefSeq:WP_008740113.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150961.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930455.1
d-fructose 1,6-bisphosphate = glycerone phosphate + d-glyceraldehyde 3-phosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_007112137.1
GO:0004332 - fructose-bisphosphate aldolase activity [Evidence IEA]
catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis, and/or gluconeogenesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
atp + 3-phospho-d-glycerate = adp + 3- phospho-d-glyceroyl phosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_007149926.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148833.1
NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
glyceraldehyde 3-phosphate dehydrogenase NAD-binding domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_011589886.1
GO:0004802 - transketolase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008929455.1
atp + l-methionine + h(2)o = phosphate + diphosphate + s-adenosyl-l-methionine
COORDINATES: similar to AA sequence:RefSeq:WP_014992622.1
GO:0004478 - methionine adenosyltransferase activity [Evidence IEA]
GO:0006556 - S-adenosylmethionine biosynthetic process [Evidence IEA]
s-adenosyl-l-homocysteine + h(2)o = adenosine + l-homocysteine
COORDINATES: similar to AA sequence:RefSeq:WP_019019763.1
GO:0004013 - adenosylhomocysteinase activity [Evidence IEA]
5-methyltetrahydrofolate + acceptor = 5,10-methylenetetrahydrofolate + reduced acceptor.
COORDINATES: similar to AA sequence:RefSeq:WP_011589890.1
GO:0004489 - methylenetetrahydrofolate reductase (NAD(P)H) activity [Evidence IEA]
methylenetetrahydrofolate reductase [NAD(P)H]
COORDINATES: similar to AA sequence:RefSeq:WP_007150313.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150129.1
GO:0004743 - pyruvate kinase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008929464.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148603.1
COORDINATES: similar to AA sequence:RefSeq:WP_011506618.1
GO:0042910 - xenobiotic transmembrane transporter activity [Evidence IEA]
GO:0009410 - response to xenobiotic stimulus [Evidence IEA]; GO:0006855 - xenobiotic transmembrane transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008929476.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151069.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589897.1
pyrimidine/purine nucleoside phosphorylase
COORDINATES: similar to AA sequence:RefSeq:WP_007149680.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149841.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148973.1
GO:0098662 - inorganic cation transmembrane transport [Evidence IEA]
functions as a cation/drug antiporter (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_011589901.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151094.1
COORDINATES: similar to AA sequence:RefSeq:WP_008734889.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149511.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150512.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151421.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148816.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151116.1
2 glutathione + H2O2 = glutathione disulfide + 2 H2O
COORDINATES: similar to AA sequence:RefSeq:WP_008929502.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589910.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150578.1
GO:0008832 - dGTPase activity [Evidence IEA]
GO:0006203 - dGTP catabolic process [Evidence IEA]
deoxyguanosinetriphosphate triphosphohydrolase
COORDINATES: protein motif:HMM:NF015018.2
COORDINATES: similar to AA sequence:RefSeq:WP_008929522.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929523.1
GO:0005509 - calcium ion binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007149139.1
COORDINATES: similar to AA sequence:RefSeq:WP_008929525.1
COORDINATES: protein motif:HMM:NF012514.2
COORDINATES: similar to AA sequence:RefSeq:WP_008929528.1
involved in disulfide-bond formation. required for the functional maturation of secreted virulence factors. transformation. acts by transferring its disulfide bond to other proteins.
COORDINATES: similar to AA sequence:RefSeq:WP_014996597.1
thiol:disulfide interchange protein DsbA/DsbL
diheme, high potential cytochrome c believed to be an intermediate electron donor to terminal oxidation systems.
COORDINATES: similar to AA sequence:RefSeq:WP_011589921.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151192.1
necessary for normal cell division and for the maintenance of normal septation (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_011589923.1
ribosome biogenesis GTP-binding protein YihA/YsxC
COORDINATES: similar to AA sequence:RefSeq:WP_008930371.1
COORDINATES: similar to AA sequence:RefSeq:WP_007114618.1
GO:0015075 - monoatomic ion transmembrane transporter activity [Evidence IEA]
GO:0034220 - monoatomic ion transmembrane transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150422.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148426.1
monovalent cation/H+ antiporter subunit D
COORDINATES: similar to AA sequence:RefSeq:WP_011589928.1
COG: NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit
COORDINATES: similar to AA sequence:RefSeq:WP_011589929.1
monovalent cation/H+ antiporter subunit A
COORDINATES: similar to AA sequence:RefSeq:WP_008930365.1
GO:0008408 - 3'-5' exonuclease activity [Evidence IEA]; GO:0003677 - DNA binding [Evidence IEA]; GO:0003887 - DNA-directed DNA polymerase activity [Evidence IEA]; GO:0003676 - nucleic acid binding [Evidence IEA]
GO:0006261 - DNA-templated DNA replication [Evidence IEA]
COORDINATES: protein motif:HMM:NF024895.2
COORDINATES: similar to AA sequence:RefSeq:WP_011589933.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150035.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148664.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151138.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149874.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589938.1
L-proline + NAD(P)(+) = L-pyrroline-5-carboxylate + NAD(P)H.
COORDINATES: similar to AA sequence:RefSeq:WP_011589939.1
GO:0004735 - pyrroline-5-carboxylate reductase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007151482.1
YggS family pyridoxal phosphate-dependent enzyme
COORDINATES: similar to AA sequence:RefSeq:WP_008928790.1
type IV pilus twitching motility protein PilT
COORDINATES: similar to AA sequence:RefSeq:WP_011589942.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928788.1
COORDINATES: similar to AA sequence:RefSeq:WP_014996668.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589945.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148745.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150237.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148814.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149941.1
GO:0008490 - arsenite secondary active transmembrane transporter activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007148877.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148977.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149407.1
GO:0051049 - regulation of transport [Evidence IEA]
phosphate signaling complex protein PhoU
COORDINATES: similar to AA sequence:RefSeq:WP_011589953.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0015415 - ATPase-coupled phosphate ion transmembrane transporter activity [Evidence IEA]
phosphate ABC transporter ATP-binding protein PstB
COORDINATES: similar to AA sequence:RefSeq:WP_007149376.1
GO:0015415 - ATPase-coupled phosphate ion transmembrane transporter activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011589955.1
phosphate ABC transporter permease subunit PstC
COORDINATES: similar to AA sequence:RefSeq:WP_011589956.1
substrate-binding domain-containing protein
TRAP-type integral membrane protein, small permease
COORDINATES: similar to AA sequence:RefSeq:WP_008928772.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149742.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928770.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928757.1
TRAP transporter substrate-binding protein
Has both ATPase and helicase activities. Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present. Involved in the postincision events of nucleotide excision repair and methyl-directed mismatch repair.
COORDINATES: similar to AA sequence:RefSeq:WP_008928756.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0003677 - DNA binding [Evidence IEA]; GO:0003678 - DNA helicase activity [Evidence IEA]; GO:0016787 - hydrolase activity [Evidence IEA]
GO:0006268 - DNA unwinding involved in DNA replication [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007150367.1
GGDEF domain-containing phosphodiesterase
COORDINATES: similar to AA sequence:RefSeq:WP_008928754.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928753.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928752.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149806.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151241.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928746.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149318.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151360.1
catalyzes two consecutive reactions converting 2',3'-cyclic-nucleotide to 3'-nucleotide and then 3'-nucleotide to nucleic acid and phosphate
COORDINATES: similar to AA sequence:RefSeq:WP_007149856.1
GO:0008663 - 2',3'-cyclic-nucleotide 2'-phosphodiesterase activity [Evidence IEA]; GO:0016788 - hydrolase activity, acting on ester bonds [Evidence IEA]; GO:0000166 - nucleotide binding [Evidence IEA]
GO:0009166 - nucleotide catabolic process [Evidence IEA]
bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase
Catalyzes efficient strand joining on a single nicked DNA. Catalytic activity: ATP + {deoxyribonucleotide}(n) + {deoxyribonucleotide}(m) = AMP + diphosphate + {deoxyribonucleotide}(n+m).
COORDINATES: similar to AA sequence:RefSeq:WP_011589973.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0003910 - DNA ligase (ATP) activity [Evidence IEA]
has an important function as a repair enzyme for proteins that have been inactivated by oxidation. catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (by similarity).
COORDINATES: similar to AA sequence:RefSeq:WP_008734854.1
COORDINATES: similar to AA sequence:RefSeq:WP_008928648.1
a na(+)/h(+) antiporter. probable involved in ph homeostasis and sodium extrusion
COORDINATES: similar to AA sequence:RefSeq:WP_007150477.1
COORDINATES: similar to AA sequence:RefSeq:WP_011589977.1
LuxR C-terminal-related transcriptional regulator
terminal oxidation (hydroxylation) of alkane
COORDINATES: similar to AA sequence:RefSeq:WP_011589978.1
COORDINATES: similar to AA sequence:RefSeq:WP_004990351.1
COORDINATES: similar to AA sequence:RefSeq:WP_020407426.1
an aldehyde + nad(+) + h(2)o = an acid + nadh
COORDINATES: similar to AA sequence:RefSeq:WP_015486579.1
converts aliphatic medium-chain-length alcohols into aldehydes. may be linked to the electron transfer chain. alcohol + acceptor = aldehyde + reduced acceptor.
COORDINATES: similar to AA sequence:RefSeq:WP_007150726.1
COORDINATES: protein motif:HMM:NF020904.2
COORDINATES: protein motif:HMM:NF016341.2
tRNA(His) guanylyltransferase Thg1 family protein
probably facilitates nickel incorporation.
COORDINATES: similar to AA sequence:RefSeq:WP_011589986.1
GO:0046872 - metal ion binding [Evidence IEA]; GO:0016530 - metallochaperone activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011589987.1
COORDINATES: protein motif:HMM:NF016819.2
acessory protein of urease, that catalyses hydrolysis of urea into ammonia and carbamic acid
COORDINATES: similar to AA sequence:RefSeq:WP_011589989.1
GO:0016151 - nickel cation binding [Evidence IEA]
GO:0006457 - protein folding [Evidence IEA]; GO:0065003 - protein-containing complex assembly [Evidence IEA]; GO:0019627 - urea metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_019017518.1
GO:0016151 - nickel cation binding [Evidence IEA]; GO:0009039 - urease activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011589991.1
GO:0035550 - urease complex [Evidence IEA]
GO:0043419 - urea catabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_000422460.1
GO:0009039 - urease activity [Evidence IEA]
COORDINATES: protein motif:HMM:NF013899.2
catalyzes the first step in hexosamine metabolism, converting fructose-6p into glucosamine-6p using glutamine as a nitrogen source (by similarity). l-glutamine + d-fructose 6-phosphate = l- glutamate + d-glucosamine 6-phosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_011589994.1
GO:0004360 - glutamine-fructose-6-phosphate transaminase (isomerizing) activity [Evidence IEA]
GO:0006040 - amino sugar metabolic process [Evidence IEA]; GO:0009252 - peptidoglycan biosynthetic process [Evidence IEA]
glutamine--fructose-6-phosphate transaminase (isomerizing)
Bifunctional enzyme responsible for the acetylation of glc-n-1-p to give glcnac-1-p and the synthesis of udp-glcnac. First catalytic activity: acetyl-coa + d-glucosamine 1-phosphate = coa + n-acetyl-d-glucosamine 1-phosphate. Second catalytic activity :utp + n-acetyl-alpha-d-glucosamine 1-phosphate = diphosphate + udp-n-acetyl-d-glucosamine.
COORDINATES: similar to AA sequence:RefSeq:WP_011589995.1
GO:0019134 - glucosamine-1-phosphate N-acetyltransferase activity [Evidence IEA]; GO:0003977 - UDP-N-acetylglucosamine diphosphorylase activity [Evidence IEA]
GO:0009103 - lipopolysaccharide biosynthetic process [Evidence IEA]; GO:0009252 - peptidoglycan biosynthetic process [Evidence IEA]
bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU
produces atp from adp in the presence of a proton gradient across the membrane
COORDINATES: similar to AA sequence:RefSeq:WP_011589996.1
GO:0046933 - proton-transporting ATP synthase activity, rotational mechanism [Evidence IEA]
GO:0015986 - proton motive force-driven ATP synthesis [Evidence IEA]
produces atp from adp in the presence of a proton gradient across the membrane. the beta chain is the catalytic subunit
COORDINATES: similar to AA sequence:RefSeq:WP_008930075.1
GO:0000275 - mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1) [Evidence IEA]; GO:0045262 - plasma membrane proton-transporting ATP synthase complex, catalytic core F(1) [Evidence IEA]; GO:0045261 - proton-transporting ATP synthase complex, catalytic core F(1) [Evidence IEA]
produces atp from adp in the presence of a proton gradient across the membrane. the gamma chain is believed to be important in regulating atpase activity and the flow of protons through the cf(0) complex
COORDINATES: similar to AA sequence:RefSeq:WP_002555983.1
GO:0045261 - proton-transporting ATP synthase complex, catalytic core F(1) [Evidence IEA]
produces atp from adp in the presence of a proton gradient across the membrane. the alpha chain is a regulatory subunit
COORDINATES: similar to AA sequence:RefSeq:WP_012072124.1
this protein seems to be part of the stalk that links cf(0) to cf(1). it either transmits conformational changes from cf(0) into cf(1) or is implicated in proton conduction
COORDINATES: similar to AA sequence:RefSeq:WP_011590000.1
COORDINATES: similar to AA sequence:RefSeq:WP_011590001.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151035.1
key component of the proton channel; it may play a direct role in the translocation of protons across the membrane
COORDINATES: similar to AA sequence:RefSeq:WP_004773235.1
GO:0045263 - proton-transporting ATP synthase complex, coupling factor F(o) [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_014996734.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148955.1
ParB/RepB/Spo0J family partition protein
ATPases involved in chromosome/plasmid partitioning, by sequence similarity
COORDINATES: similar to AA sequence:RefSeq:WP_007151340.1
probably involved in the regulation of cell devision
COORDINATES: similar to AA sequence:RefSeq:WP_007148910.1
GO:0046118 - 7-methylguanosine biosynthetic process [Evidence IEA]; GO:0031167 - rRNA methylation [Evidence IEA]
16S rRNA (guanine(527)-N(7))-methyltransferase RsmG
COORDINATES: similar to AA sequence:RefSeq:WP_011590007.1
GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]
GO:0008033 - tRNA processing [Evidence IEA]; GO:0002098 - tRNA wobble uridine modification [Evidence IEA]
tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG
COORDINATES: similar to AA sequence:RefSeq:WP_007149957.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930089.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930091.1
GO:0004451 - isocitrate lyase activity [Evidence IEA]
GO:0019752 - carboxylic acid metabolic process [Evidence IEA]
Biosynthesis of wax esters and triacylglyceroles
COORDINATES: similar to AA sequence:RefSeq:WP_008930092.1
COORDINATES: similar to AA sequence:RefSeq:WP_007151467.1
transcription regulation, by sequence similarity
COORDINATES: similar to AA sequence:RefSeq:WP_018233304.1
COORDINATES: similar to AA sequence:RefSeq:WP_008930096.1
SprT family zinc-dependent metalloprotease
COORDINATES: similar to AA sequence:RefSeq:WP_014996749.1
COORDINATES: similar to AA sequence:RefSeq:WP_011590017.1
COORDINATES: similar to AA sequence:RefSeq:WP_011590018.1
COORDINATES: similar to AA sequence:RefSeq:WP_007148776.1
COORDINATES: similar to AA sequence:RefSeq:WP_007150221.1
COORDINATES: similar to AA sequence:RefSeq:WP_007149360.1
carboxymuconolactone decarboxylase family protein
involved in the biosynthesis of the hypermodified nucleoside 5- methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs (by similarity)
COORDINATES: similar to AA sequence:RefSeq:WP_011590022.1
GO:0005525 - GTP binding [Evidence IEA]; GO:0003924 - GTPase activity [Evidence IEA]; GO:0005515 - protein binding [Evidence IEA]
tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE
possible preprotein translocase subunit YidC
COORDINATES: similar to AA sequence:RefSeq:WP_011590023.1
GO:0032977 - membrane insertase activity [Evidence IEA]
site specific endonuclease that generates mature tRNAs by cleaving-off the leader sequences at their 5'ends
COORDINATES: protein motif:HMM:NF013022.2
GO:0004526 - ribonuclease P activity [Evidence IEA]
one of the proteins from the large subunit of the prokaryotic ribosome
COORDINATES: similar to AA sequence:RefSeq:WP_011508608.1