Cryptosporidium parvum Iowa II chromosome 5, whole genome shotgun sequence.
Eukaryota; Alveolata; Apicomplexa; Conoidasida; Coccidia; Eucoccidiorida; Eimeriorina; Cryptosporidiidae; Cryptosporidium.
Complete genome sequence of the apicomplexan, Cryptosporidium parvum
Submitted (06-MAR-2007) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (02-APR-2004) Veterinary Pathobiology, University of Minnesota, 1988 Fitch Ave., St. Paul, MN 55108, USA
PROVISIONAL REFSEQ: This record has not yet been subject to final\nNCBI review. The reference sequence was derived from CM000433.
signal peptide containing large protein with proline stretches
RRPp/PMC2 like exosome 3'-5' exoribonuclease subunit with an RNAseD domain and an HRDc domain
ferlin like type II membrane associated protein with 5 C2 domains and a transmembrane domain or GPI anchor sequence at the C-terminus
hypothetical protein with signal peptide
Unc45-like TPR repeat containing protein
signal peptide containing protein with 6 transmembrane domains
hypothetical protein, 6 transmembrane domains
putative polyphosphate synthetase VTC4, 3 transmembrane domains at C-terminus
polyphosphate synthetase VTC4, 3 transmembrane domains at C-terminus
carboxylesterase, lysophospholipase, signal peptide
signal peptide containing protein with threonine stretches,possible mucin
domain similar to COG3889, predicted solute binding protein, signal peptide plus thr stretch, possible mucin
conserved protein with 2 transmembrane domain
putative eukaryotic translation initiation factor 3
eukaryotic translation initiation factor 3
protein with 4 PHD domains plus a SET domain and associated cysteine cluster at the C-terminus
70 kDa peptidylprolyl isomerase, putative
protein with 2 CAP (CARP) domains, possible adenyl cyclase-associated protein
similar to bacterial glycerophosphodiester phosphodiesterase, signal peptide
large hypothetical protein with region conserved in plasmodium
MJ1157-like thiouridine synthase (Pploop atpase) plus Zn ribbon. involved in RNA metabolism.
hypothetical protein, 5 transmembrane domains near N-terminus
hypothetical protein with 5 transmembrane domains near N-terminus
hypothetical protein with possible transmembrane domain within C
a neighboring region contains significant homology suggestive of an exon. Experimental evidence is needed to validate the annotation.
two conserved domains: 1. cd00635, YBL036c_PLPDEIII, PLP dependent enzymes class III (PLPDE_III). These proteins are classified as PyridoxaL 5'-phosphate Dependent Enzymes class III; 2. COG0325, Predicted enzyme with a TIM-barrel fold
protein with 4 ankyrin repeats plus a bromodomain.
reptin52; reptin like TIP49 family AAA+ ATpase
eukaryotic translation initiation factor 3 37.28 kDa subunit, putative
eukaryotic translation initiation factor 3 37.28 kDa subunit
extracellular protein with a ricin domain and a family 2 glycosyltransferase domain
musashi. RRM domain containing protein, splicing related
choline/ethanolamine kinase family protein
complementary to 18S rRNA; methylates base A
Mdh; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+)
hypothetical protein containing a signal peptide
conserve protein having a signal peptide
calcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands
membrane associated protein with a transmembrane domain near C-terminus
protein with conserved domain that is fused in vertebrates to neuralized domain repeats
Pre-mRNA splicing factor Pro1/Prp6. HAT repeat protein
Csn12p/Rpn3p family protein; component of the COP9 signalsome
Oxr1p like TLDc domain containing protein
apicomplexan conserved protein with 9 transmembrane domain
arfgap'arfgap like finger domain containing protein'
CCCH RNA binding domain involved in RNA metabolism
containing protein with orthologs in plasmodium
WD-40 repeat protein family / small nuclear ribonucleoprotein Prp4p-related
cinnamyl-alcohol dehydrogenase-like nucleoside diphosphate sugar epimerase
POZ domain protein that is fused to a MATH domain at its N-terminus
nucleolar protein NOP4; rrm domain containing protein
ring finger and bbox containing protein, putative
hypothetical protein with Thr stretches, possible mucin
Tsr1p GTpase, multitransmembrane region protein
hypothetical protein with transmembrane domain near N-terminus
DHHC family palmitoyl transferase with a signal peptide and 4 transmembrane domain
conserved protein having 3 transmembrane domains and possible ER retention motif; possible ER protein
tfc4p like TFIIIC subunit; TPR repeat containing basal transcription factor
membrane associated adenyl cyclase with 2 transmembrane regions and an adenylyl cyclase domain
hypothetical protein with 3 transmembrane domains
conserved protein with possible signal peptide and ER retention motif; possible ER protein
SPAC25G10.01-like RRM domain containing protein
similar to NC_001141 protein required for filamentous growth, cell polarity, and cellular elongation
F11M21.28-like protein having 3 CCCH RNA binding domains; involved in RNA metabolism
paralog within cryptosporidium-specific HCD multi-gene family
signal peptide containing protein having a NDK (nucleoside-diphosphate kinase) domain
cysteine rich protein having a signal peptide
with a signal peptide and cryptosporidium paralogs
hypothetical protein having a signal peptide
with signal peptide and possible cryptosporidium paralog
domain similar to KOG4115, dynein-associated protein roadblock
hypothetical protein, 2 transmembrane domains near C-terminus
YIP1 protein like transporter GTpase interacting factor having 5 transmembrane domain
translation initiation factor if-2B beta; eIF-2
hypothetical protein, possibly apicomplexan conserved
hypothetical protein with short conserved N-terminal motif, possible cysteine binding domain
protein with signal peptide, and 11 transmembrane domains
hypothetical protein with signal peptide and acidic stretch
hypothetical protein with conserved apicomplexan domain
protein with an N-terminal domain shared with the TOG/ALp4p ike microtubule associated proteins
nclip/MJ0026/YebU-like; SUN family methylase
conserved protein, possible U4/U6 associated RNA splicing factor
conserved protein with N-terminal HORMA domain
small nucleolar RNP protein, Gar1 protein RNA binding region
SMART 2xt_SNARE domain containing protein
F11M21.28-like 3 CCCH RNA binding domain protein involved in RNA metabolism
GPI1/PIG-Q like N-acetylglucosaminyl-phosphatidylinositol transferase involved in GIP anchor biosynthesis
LETM1/MRS7 family protein with a transmembrane region at the N-terminus
conserved probable chaperonin containing TCP-1 delta subunit
pleckstrin homology (PH) domain containing protein
large low complexity protein with predicted coiled coil regions
hypothetical protein with 5 transmembrane domains
enolase (2-phosphoglycerate dehydratase)
AtPH1 like protein with a pleckstrin homology (PH) domain
protein with RIO domain within N-terminal region
nuclear VCP like protein with 2 AAA ATpase domains
with signal peptide followed by SCP domain and a cryptosporidium specific repeat
dolichol phosphate mannose synthase, putative
protein with forkhead associated (FHA) domain within N-terminal region and possible central coiled coil domain
hypothetical protein with signal peptide and mucin-like threonine repeats
protein with PHD finger and a nipped-B/Mis4/Scc2 like domain at the C-terminus
DNA methyltransferase PMT1 - like protein
protein with conserved N-terminal localized cysteine-rich domain; predicted archaeo-eukaryotic ribosomal protein
chromatin associated proein with a chromodomain at the C-terminus
protein with signal peptide and 8 transmembrane domains; possible ZIP zinc transporter family member
large low complexity protein with proline/alanine-rich repeat
T8M16_190-plant like protein with RRM domain
small nuclear ribonucleoprotein D1. SM domain containing protein
DPAGT1 like N-acetylglucosamine-1-phosphate transferase
maternal embryonic leucine zipper kinase
hypothetical protein with possible transmembrane domain within N-terminus
DAD1/Ost2 like dolichyl-diphospho-oligosaccharide-protein glycosyltransferase, epsilon unit
Sin3 like paired amphipathic helix containing protein
SnRNP assembly defective 1 like ubiquitin C-terminal hydrolase with a UBP finger at the N-terminus
p27 like 26S proteasomal subunit with a PDZ domain
60S acidic ribosomal protein LP1 like protein of possible plant origin
unchacterized apicomplexan-specific serine rich low complexity protein
conserved protein of possible plant or bacterial origin
conserved possible esterase of the beta-lactamase family, of possible plant or bacterial origin, possible transmembrane domain within N terminal region
Ylr401cp-like protein with 2 CCCH domains plus Dus1p tRNA dihydrouridine synthase Tim barrel
RNA binding RGG repeats plus RRM domain containing protein
hypothetical protein with 5 transmembrane domains within C terminus
ubiquitin C-terminal hydrolase of the cysteine proteinase fold
Cdc2-like CDK2/CDC28 like protein kinase
similar to MED6, RNA polymerase II transcriptional regulation mediator
protein with 12 transmembrane domains, possible apicomplexan-specific protein
hypothetical protein with signal peptide, possible transmembrane domain near C-terminus and predicted SMART Znf_C2H2 domain
Alg5 like dolichyl-phosphate beta-glucosyltransferase
putative leucine aminopeptidase; of possible plant or bacterial origin
leucine aminopeptidase; of possible plant or bacterial origin
phosphoglycerate mutase family protein; possible fructose bisphosphate phosphatase
penguin protein containing pumolio repeats
60S ribosomal protein L7-B; Rp17bp; L30 RNA binding domain
little finger (CxxC...CxxC) domain containing protein
predicted mannitol dehydrogenase; zinc dependent alcohol dehydrogenase like rossmann fold
mannitol dehydrogenase; zinc dependent alcohol dehydrogenase like rossmann fold
hypothetical protein with a signal peptide plus 6+ transmembrane domains
hypothetical protein with a signal peptide
large protein containing a signal peptide
with a signal peptide, paralog of cryptosporidium-specific WYLE gene family
katanin p60/fidgetin family with AAA ATpase
ULP1 like chllamydin domain containing protease
chorein/VPS13 like protein involved in vacuolar transport
hypothetical protein with 4 transmembrane domains near carboxy terminus
F11M21.28-like; 3 CCH RNA binding domain protein involved in RNA metabolism
C1p1p GTpase. Pre-mRNA cleavaage complex protein
protein phosphatase C2 (PP2c) domain containing protein
forkhead associated domain (FHA) containing protein
U5snrp Brr2 SFII RNA helicase (sec63 and the second part of the RNA
hypothetical protein with transmembrane domain within C-terminal region
hypothetical protein with possible plus3 domain
acetylcholinesterase'secreted acetylcholinesterase of the alpha/beta hydrolase superfamily'
hypothetical protein containing a possible signal peptide
large hypothetical protein with 8 or more transmembrane domains
LPS glycosyltransferase of possible cyanobacterial origin
large hypothetical protein with signal peptide
proteasome subunit beta7; NTN hydrolase fold
secreted lipopolysaccharide sugar transferase like family 8 glycosyltransferase
RNA recognition motif (RRM)-containing protein
putative vacuolar ATP synthase subunit d
protein with signal peptide and possible kazal domain
mitochondrial processing peptidase beta subunit
possible phosphate/phosphoenolpyruvate translocator with 9 transmembrane domains
with the following domain organization: signal peptide-Tox1-notch-TSP(13)-Tox1-notch-Tox1-notch-Tox1- notch-Tox1-Tox1-notch-Tox1(4)-sushi(4)
DNAj protein with possible transmembrane domain within C-terminal region
nascent polypeptide associated complex alpha chain with an NAC domain
nucleotidase (5'-nucleotidase/2'-cyclic phosphodiesterase) of the calcineurin superfamily
hypothetical protein with possible conserved HGG motif
hypothetical protein having 10 transmembrane domains
chaperone'DNAj domain protein chaperone'
similar to transcription initiation factor IIIB
CNcl1p/MJ0026/YebU-like. SUN family methylase
paralog within GGC family of cryptosporidium-specific secreted proteins, signal peptide
similar to bacterial SbmA, possible bacterial origin, 5 transmembrane domain, signal peptide, cryptosporidium paralogs
paralog within FGLN family of cryptosporidium-specific proteins
ankyrin repeat protein having a possible transmembrane domain
40S ribosomal protein S12. pelota RNA binding domain containing protein
hypothetical protein with a possible cysteine-rich domain (BBOX zinc finger?)
vacuole membrane protein, VMP1 like integral membrane protein
adapter-protein complex 1 gamma subunit (gamma adaptin)
yprA. Lhr1/Ski2 family RNA SFII helicase
possible apicomplexan specific, low complexity protein
protein with RING finger domain at C-terminus
hypothetical protein, possible apicomplexan-specific
complementary to 25S rRNA at position 897; methylates base G
secreted protein of the alpha beta hydrolase superfamily
protein with 3 transmembrane domains, ring domain, and possible signal peptide
hypothetical protein with possible transmembrane domain near N-terminus
protein with 4 transmembrane domains, signal peptide and a RING domain
hypothetical protein with 4 transmembrane domains
with N-terminal region ZnF U1 domain, similar to U1 snRNP-specific protein
DHR1/Ecm16p/kurz. HrpA family SFII helicase
hypothetical protein conserved in apicomplexa
hypothetical protein having a signal peptide and transmembrane domain near C-terminus
hypothetical protein with 4 transmembrane domains within C-terminus
vacuolar protein-sorting protein VPS45, putative
Pre2p/proteasome subunit beta type 5; NTN hydrolase fold
membrane associated protein with a signal peptide, EGF domain and 7 transmembrane domains at the C-terminus
hypothetical protein with signal peptide and transmembrane region at C-terminus, possible N-terminal region transmembrane domain
hypothetical protein with signal peptide and possible transmembrane region at C-terminus
hypothetical protein with 3 transmembrane domains near C-terminus
hypothetical protein with 7 transmembrane domains
with carboxy terminus similar to n-acylaminoacyl-peptide hydrolase
MJ0710-like (thump + methylase domains). RNA methylase
thymidine kinase of likely bacterial origin
hypothetical protein with 8 transmembrane domains
CpTSP7; extracellular membrane associated protein with a signal peptide followed by 2 TSP1 repeats, an EGF domain and a transmembrane region
large low complexity protein, possible apicomplexan-specific
low complexity, limited similarity to gi|23485899|
possible vacuolar protein sorting associated protein (VPS)
with signal peptide and 2 cryptosporidium-specific paralogs
asparagine synthetase A (AsnA) like protein
tryptophan synthase trpB of possible bacterial origin
with signal peptide, cryptosporidium telomeric MEDLE family of secreted protein