Cryptosporidium parvum Iowa II chromosome 4, whole genome shotgun sequence.
Eukaryota; Alveolata; Apicomplexa; Conoidasida; Coccidia; Eucoccidiorida; Eimeriorina; Cryptosporidiidae; Cryptosporidium.
Complete genome sequence of the apicomplexan, Cryptosporidium parvum
Submitted (06-MAR-2007) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (02-APR-2004) Veterinary Pathobiology, University of Minnesota, 1988 Fitch Ave., St. Paul, MN 55108, USA
PROVISIONAL REFSEQ: This record has not yet been subject to final\nNCBI review. The reference sequence was derived from CM000432.
hypothetical protein having a signal peptide, telomeric gene
ORF structures, BLASTX, and comparsion with Cryptosporidium hominis suggest that there are three genes in this region; these three genes are named cgd4_30, cgd4_31, cgd4_32; experimental evidence is needed to validate the annotation
manually annotated according to blastx results and ORFs. See cgd4_30
APG7-like ubiquitin activating enzyme E1
extracellular membrane associated protein with a signal peptide, an EGF domain followed by 10 transmembrane domains
similar to ligatin, PUA domain plus SUI1 RNA binding domain
RRM domain and KH domain protein (SPAC30D11.14-like KH)
hypothetical protein, possible transmembrane domain within N-terminus
large low complexity coiled coil protien with large repeat region
Ubc1p like ubiquitin-conjugating enzyme E2 fused to a UBA domain (UBC+UBA)
hypothetical protein containing a signal peptide
proteasome subunit alpha type 4, NTN hydrolase fold
30 kDa splicing factor, SPF 30, tudor domain containing protein
hypothetical protein with transmembrane domain near C-terminus
putative protein phosphatase 2A regulatory B subunit
protein phosphatase 2A regulatory B subunit
possible bacterial origin, no plasmodium hits
CCAAT-binding factor chain HAP5 like histone
protein with possible conserved beta tubulin folding factor domain
hypothetical protein with 7 transmembrane domains
hypothetical protein with 5 transmembrane domains
protein with a SET domain within carboxy region
protein with signal peptide plus 12 transmembrane domain domain protein, possible tranporter
protein with 8 transmembrane domains, possible amino alcohol phosphotransferase
complementary to 25S rRNA at position 2922; methylates base C
signal peptide + 4 transmembrane domain protein
XPG, DNA excision repair protein, flap endonuclease
26S proteasome regulatory subunit 5a with a vWA domain and two ubiquitin interacting motifs (UIM)
putative vacuolar ATP synthase subunit C
amino terminal region conserved in plasmodium and perhaps wider conservation
similar to NTF2, domain found in RNA transport proteins
extracellular protein with a signal peptide, FN3 domain and a predicted transmembrane region
ZnKn (C2HC)+Athook+bromo domain protein, Taf250, transcription initiation factor IID
Nip7 like PUA domain containing protein involved in ribosomal biogenesis
pyruvate:ferredoxin oxidoreductase/NADPH-cytochrome P450 reductase PNO
conserved protein of possible plant or bacterial origin
Ynr054cp, basal transcriptional activator hABT1, RRM domain containing protein
putative nucleosome assembly protein 19075338; besthit Py 23481872
nucleosome assembly protein 19075338; besthit Py 23481872
extracellular protein with a signal peptide and 8 kazal repeats
possible ASF1 anti-silencing function 1 like protein
ASF1 anti-silencing function 1 like protein
Low complexity protein with large Glu repeat
UDP-N-acetylglucosamine pyrophosphorylase
hypothetical protein with signal peptide
ADA2 ortholog with a ZZ finger, SANT domain and a SWIRM domain
similar to acid phosphatase, signal peptide, duplicated adjacent gene
pap1p; poly A polymerase (eukaryotic type)
DNA replication licensing factor MCM7 like AAA+ ATpase
hypothetical protein with 7 transmembrane domains, possible signal peptide
eukaryotic translation initiation factor
experimental evidence is needed to validate the annotation
similar to disulfide isomerase, signal peptide +ER retention signal
WD40 repeat containing protein that has a transmembrane region at the C-terminus
PhnP like hydrolase of the metallobetalactamase fold
conserved in plasmodium and plants, possible signal peptide
hypothetical conserved protein with possible signal peptide
conserved protein with transmembrane region at C-terminus
26S proteasome regulatory subunit S4 like AAA ATpase
hypothetical protein, possible apicomplexan conserved
ubiquitin fusion degradation protein (UFD1); double Psi beta barrel fold
similar to ribosome synthesis protein, yeast RRS1
transcription factor TFIIIB, SANT domain
small hypothetical protein, possible conserved
uncharacterized secreted protein with thr rich regions, possible mucin
hypothetical protein with transmembrane domain
NADPH-dependent FMN FAD containing oxidoreductase
possible ABC transporter with 11 transmembrane domains, AAA domain
possible ABC transporter with two AAA domains and 14 transmembrane regions
possible ABC transporter with AAA domain and 12 transmembrane domains
similar to pyrophosphate phospho-hydrolase
hypothetical protein, possible transmembrane domain near N-terminus
vacuolar proton translocating ATpase with 7 transmembrane regions near C-terminus
BMS1 like GTpase involved in ribosome biogenesis
similar to undecaprenyl pyrophosphate synthetase
Brx1p nucleolar protein required for biogenesis of the 60S ribosomal subunit
hypothetical protein, possible conserved
chromodomain-helicase-DNA-binding'multidomain chromatin protein with the following architecture: chromo-bromo-chromo-SNF2 ATpase'
complementary to 25S rRNA at position 3045; methylates base C
possible thioredoxin H-type of possible fungal or plant origin, small protein
small nuclear ribonucleoprotein, putative
hypothetical protein with signal peptide and 3 to 6 transmembrane domains
similar to yeast Brr6p, 2 transmembrane domains and a NFX like finger
hypothetical protein with 2 transmembrane domains
hypothetical protein with 4 transmembrane domains
Dbp7p, eIF4A-a-family RNA SFII helicase (DEXDc+HELICc)
hypothetical protein with 10 transmembrane domains
with domain similar to a family of Arabidopsis proteins, transmembrane domain near N-terminus
possible origin recognition complex protein subunit 2, orc2
protein with central transmembrane domain followed by gly-met-pro repeat
similar to an accessory factor associated with RNA polymerase II by affinity chromatography; Cdc73p
similar to vacuole import and degradation protein VID27
centromeric histone h3-like protein, cse4 like
SMART RPR domain at NH2 terminus, SMART AZnF_C2H2
domain similar to KOG1564, DNA repair protein RHP57
DHHC family palmitoyl transferase with 4 transmembrane regions
PIG-A like N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein
similar to ribonuclease HI large subunit (RNase HI large subunit)
hypothetical protein with 12+ transmembrane domains
membrane associated aspartyl protease with a transmembrane domain at the C-terminus
N-terminal region similar to putative epsilon-adaptin, probable adaptin
possible double-stranded DNA-binding domain, small conserved protein
putative phosphopantothenoylcysteine synthetase
ribosomal protein PO like protein of the L10 family
oxidoreductase, short-chain dehydrogenase family, putative
oxidoreductase, short-chain dehydrogenase family
multitransmembrane protein with signal peptide and GMGPP repeat at C-terminus
DSK2 like protein with a ubiquitin domain, 2 STI1 motifs and a UBA domain at its C-terminus
lysyl-tRNA synthetase (NOB+tRNA synthetase)
similar to vacuolor VPS35 protein-sorting protein
extracelllular membrane associated protein with a signal peptide, 5 ankyrin repeats, SUSHI domain and a transmembrane region
hypothetical protein containing a signal peptide and 2 transmembrane domains
small hypothetical protein with signal peptide
with 2xCARP domains similar to beta-tubulin cofactor C or retinitis pigmentosa 2 like
hypothetical protein with a signal peptide, gene within locus of signal-peptide containing hypothetical proteins
hypothetical protein, signal peptide, 2 transmembrane domains near C-terminus
26S proteasome regulatory subunit 26b like AAA ATpase
putative farnesyl pyrophosphate synthase
phospholipase C, delta 1 ortholog with 2 EF hands plus phospholipase C domain plus C2 domain
oxysterol binding protein 1A-like pleckstrin homology (PH) domain containing protein
glycerophosphodiester phosphodiesterase-like protein
similarity at COOH terminus with programmed cell death protein 2
FRP1 like protein involved in DNA repair with a FAT domain and a phosphatidylinositol kinase domain at the C-terminus
N-methyl-D-aspartate receptor-associated protein, 7 transmembrane domain protein
sec7 domain containing protein, possibly of plant origin
probable NADPH-cytochrome p450 reductase
P-type ATpase involved in cation transport
IMP4 U3 small nucleolar ribonucleoprotein
11 transmembrane domain protein, possible aa transporter
DNAj domain protein having a signal peptide
putative ethanolaminephosphotransferase (ETHPT) 9 transmembrane domain protein involved in lipid metabolism
ethanolaminephosphotransferase (ETHPT) 9 transmembrane domain protein involved in lipid
hypothetical protein having a signal peptide
Mra1/NEP1 like protein, involved in pre-rRNA processing, adjacent genes putative paralogs
Mra1/NEP1 like protein, involved in pre-rRNA processing, adjacent genes paralogs
putative sugar transporter, 12x transmembrane domain protein
sugar transporter, 12x transmembrane domain protein
vacuolar sorting protein VPS52/suppressor of actin Sac2-family protein
ERCC4/XP-G-type excision repair nuclease
RAD1, NH2 terminal ERCC4-like helicase domain
RhoGAP domain containing protein with a Sec14D domain at the N-terminus
Dbp1p, eIF4a-1 family RNA SFII helicase (DEXDC+HELICc)
hypothetical protein with a signal peptide
ribosomal protein S27a, ubiquitin plus zincribbon, UB13p
acyc domain containing protein, similar to dictyostelium SSgcA
10 transmembrane domain protein, possible translocator
ALG6-like dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase
putative eIF6, translation initiation factor 6
cullin-like protein of probable plant origin
putative mitochondrial inner membrane translocase
mitochondrial inner membrane translocase
Rrp3p, eIF4A-1-family RNA SFII helicase (DEXDc+HELICc)
possible NLI interacting factor CTD-like phosphatase
Trm1p. N2,N2-dimethylguanosine tRNA methyltransferase
putative DNA-directed RNA polymerases I, II, and III 8.3 kda polypeptide
DNA-directed RNA polymerases I, II, and III 8.3 kda polypeptide
heat shock 105kD; heat shock 105kD alpha; heat shock 105kD beta; heat shock 105kDa protein 1
articulin family protein, adjacent paralogous gene
Noc3 like protein involved in nuclear export of pre-ribosomes
pleckstrin homology (PH) domain containing protein
apicomplexan specific zinc cluster protein with cryptosporidium paralogs
neutral sphingomyelinase activation associated factor-like BEACH domain containing protein
putative long chain fatty acyl CoA synthetase having a signal peptide
long chain fatty acyl CoA synthetase having a signal peptide
Vps53-N family protein involved invacuolar protein sorting
hypothetical protein with signal peptide and central coiled-coil region, within large locus of signal peptide containing proteins
hypothetical protein with signal peptide, within large locus of signal peptide containing proteins
large low complexity protein with signal peptide, within large locus of signal peptide containing proteins
hypothetical protein with signal peptide, within larege locus of signal peptide containing proteins
hypothetical protein with signal peptide and transmembrane domain near C, within large locus of signal peptide containing proteins
hypothetical protein with signal peptide plus possible GPI anchor or transmembrane domain near C-terminus, within large locus of signal peptide containing proteins
hypothetical protein with signal peptide and repeats, within large locus of signal peptide containing proteins
large hypothetical protein with signal peptide, within large locus of signal peptide containing proteins
with signal peptide and an apicomplexan-conserved cysteine-rich COOH terminal domain and cryptosporidium paralog; similar to gi:23619168 and gi:27368927
secreted protein with signal peptide and 12 KAZAL repeats and a mucin-like stretch of threonines
paralog within cryptosporidium-specific HCD gene family, gene within HCD geme family locus, no good start Met
with signal peptide, paralog within HCD family of putative cryptosporidium secreted protein, gene within HCD gene locus
with signal peptide and transmembrane domain, cryptosporidium HCD gene family paralog, within HCD gene locus
hypothetical protein with possible signal peptide, 'HCD family'paralog
domain similar to KOG0260, KOG1984, KOG1999, repeats; identical to cryptosporidium GSS tag 11990219, signal peptide
with signal peptide, possible cryptosporidium specific paralog
large glycine-rich repeat low complexity protein
possible cryptosporidium-specific paralog
Ydr140wp-like HemK family methylase. archaeal-like. RNA methylase
Experiment is needed to validate the annotation
similar to translation initiation factor if-3 subunit 8, PINT domain
Rrp8p like methyltransferase involved in rRNA processing
putative transcription factor IIE alpha subunit
Ank repeat protein with possible signal peptide
Ank, ankyrin repeats containing protein with 9 transmembrane domains at C-terminus
putative t-complex protein 1, gamma subunit
TCP-1/cpn60 chaperonin family, T-complex protein subunit 7 (eta)
emap RNA binding domain protein (N terminal low complexity region)
signal peptide plus transmembrane domain or GPI anchor, proline rich, acidic stretches
hypothetical protein with possible transmembrane domain near N-terminus
complementary to 18S rRNA; methylates base U
possible ribosomal-protein-alanine acetyltransferase
40S ribosomal protein S2/S5. DSRBD RNA binding domain
putative transporter with signal peptide and 12 transmembrane domains
transporter with signal peptide and 12 transmembrane domains
B-box zinc finger domain containing protein
hypothetical conserved protein, possible transmembrane domain near C-terminus
similar to SEL1L with 1 or 2 transmembrane domains near C-terminus
hypothetical protein with signal peptide plus transmembrane domain
domain similar to KOG2065, gamma-tubulin ring complex protein
possible transporter with 11 transmembrane domains
dihydrofolate reductase-thymidylate synthase
putative secreted, membrane-associated protein
with a signal peptide plus transmembrane domain. member of cryptosporidium-specific FGLN gene family. adjacent paralog gene.
with signal peptide, paralog of cryptosporidium-specific SKSR family
signal peptide containing cysteine rich protein, gene anchored to telomere.