Zymoseptoria tritici IPO323 chromosome 3, whole genome shotgun sequence.
Zymoseptoria tritici IPO323 (Mycosphaerella graminicola IPO323)
Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes; Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Zymoseptoria.
Finished Genome of the Fungal Wheat Pathogen Mycosphaerella graminicola Reveals Dispensome Structure, Chromosome Plasticity, and Stealth Pathogenesis
Submitted (06-FEB-2020) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (18-MAY-2011) US DOE Joint Genome Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598-1698, USA
PROVISIONAL REFSEQ: This record has not yet been subject to final\nNCBI review. The reference sequence is identical to CM001198.\nURL -- http://www.jgi.doe.gov/Mgraminicola\nJGI Project ID: 4000758\nThe DNA was provided by G.H.J. Kema (gert.kema@wur.nl)\nThe strain is available from Fungal Biodiversity Center,\nhttp://www.cbs.knaw.nl\nContacts: Stephen B. Goodwin (sgoodwin@purdue.edu)\n Gert H. J. Kema (gert.Kema@wur.nl)\n Igor Grigoriev (ivgrigoriev@lbl.gov)\nAssembly and annotation done by JGI.\n\n##Genome-Assembly-Data-START##\nAssembly Method :: JAZZ v. 1.0\nAssembly Name :: MYCGR v2.0\nGenome Coverage :: 8.9X\nSequencing Technology :: Sanger\n##Genome-Assembly-Data-END##\n\n##Metadata-START##\nOrganism Display Name :: Mycosphaerella graminicola IPO323\nGOLD Stamp ID :: Gi00795\n##Metadata-END##\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: INSDC submitter\nAnnotation Status :: Full annotation\nAnnotation Pipeline :: Eukaryotic Annotation Propagation Pipeline\n##Genome-Annotation-Data-END##
culture from epitype of Zymoseptoria tritici
G-protein coupled receptorG-protein-coupled receptor
RNA polymerase II-associated protein similar to Saccharomyces cerevisiae Paf1 protein (Paf1p) which is required for methylation of lysine 9 and 79 of histone H3 and telomere-associated gene silencing
P450 with unknown function. Both multiple seq alignment and NJ cluster analysis and local similarity search did not identify characterized P450 significantly similar to this model. A putative salicylate esterase and an aromatic-ring hydroxylase are found next to this gene.
Ca2+-modulated nonselective cation channel polycystin
related to intracellular calcium signaling
Actin-related protein; putative homolog of the Saccharomyces cerevisiae SWI-SNF complex protein ARP6 protein
Oligopeptide transporter superfamily protein (Pfam: PF03169) with 13 transmembrane regions.
P450 monooxygenase with unknown function
oligopeptide transporter OPT superfamily protein
Oligopeptide transporter superfamily protein, contains PFAM PF03169 and 16 predicted transmembrane regions.
phosphohexokinase; phosphofructokinase I; phosphofructokinase (phosphorylating); 6-phosphofructose 1-kinase; ATP-dependent phosphofructokinase; D-fructose-6-phosphate 1-phosphotransferase; fructose 6-phosphate kinase; fructose 6-phosphokinase; nucleotide triphosphate-dependent phosphofructokinase; phospho-1,6-fructokinase; GO:0005737 cytoplasm; GO:0005945 6-phosphofructokinase complex
Alpha-L-Rhamnosidase (Signal P secreted)
glycine dehydrogenase [decarboxylating], mitochondrial
fungal transcriptional regulatory protein
pyruvate dehydrogenase (acetyl-transferring); MtPDC (mitochondrial pyruvate dehydogenase complex); pyruvate decarboxylase; pyruvate dehydrogenase; pyruvate dehydrogenase (lipoamide); pyruvate dehydrogenase complex; pyruvate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-acetylating); pyruvic acid dehydrogenase; pyruvic dehydrogenase
ABC transporter domain-containing protein
Non transporter ABC protein, ABC-F family, GCN / EF3 type. EF-3 Elongation factor 3 ABC proteins are cytosolic proteins required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1:GTP:aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site.
transaldolase; dihydroxyacetonetransferase; dihydroxyacetone synthase; formaldehyde transketolase
Copper, zinc containing superoxide dismutase; catalyses the conversion of superoxide radicals to hydrogen peroxide and, or molecular oxygen.
Component of the ATP-dependent Isw2p-Itc1p chromatin remodeling complex
1,2-Alpha-Mannosidase (Signal P Anchor) (Glycosyl Hydrolase Family 47)
Beta-Fructofuranosidase (Invertase) (Glycosyl Hydrolase Family 32)
Shows sequence similarity to IMP1; Catalytic subunit of the mitochondrial inner membrane peptidase complex, required for maturation of mitochondrial proteins of the intermembrane space; complex contains Imp1p and Imp2p (both catalytic subunits), and Som1p [] [Saccharomyces cerevisiae].
HMMPfam hit to Peptidase S28, Serine carboxypeptidase S28. Has a predicted signal peptide.
HMMPfam hit to Peptidase_S28, Serine carboxypeptidase S28. Has a signal peptide.
MgPP2C2, protein phosphatase 2C protein 2
structural maintenance of chromosome protein 3
SMC3 subunit of the condensin complex, which reorganizes chromosomes during cell division; coiled-coil protein of the SMC family involved in chromosome condensation and segregation
related to intracellular calcium signal levels
Cis,cis-muconate lactonizing enzyme(MLE). This enzyme is part of the beta-ketoadipate pathway.
ABC transporter, ABC-A family. Probably belonging to the AOH type. This family has no homologs in yeast. The ABCA subfamily is involved in lipid transport. Members of this subfamily are exclusively found in eukaryotes and display an IM-ABC or an (IM-ABC)2 organization, similar to that of the MDR family of exporter.
putative SMF protein involved in iron and manganese uptake
Hypothetical guanine nucleotide exchange factor (GEF) for Cdc42p
beta ketoadipate:succinyl-CoA transferase, TR2
Putative beta ketoadipate:succinyl-CoA, part of the beta ketoadipate pathway.
1,3-beta-glucanosyltransferase-like protein
similar to 1,3-beta-glucanosyltransferase encoding gene
putative phosphopantetheinyl transferase
Putative phosphopantetheinyl transferase, homologous to NpgA protein of Aspergilli. Protein contains a Sfp domain (Phosphopantetheinyl transferase) These proteins mediate posttranslational attachment of a prosthetic 4 phosphopantetheine to a acylcarrier or peptidylcarrier domain.
zinc finger DHHC domain-containing protein
ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN
54S ribosomal protein L38, mitochondrial
Squalene epoxidase, catalyzes the epoxidation of squalene to 2,3-oxidosqualene; plays an essential role in the ergosterol-biosynthesis pathway
Exo-Beta-1,3-Glucanase (Signal P secreted)
Complete WSC Domain, which is present in fungal exo-glucanases || Also might be the receptor in the cell wall integrity pathway
Similar to beta ketoadipyl CoA thiolase, last step of the ketoadipate pathway.
Glucan 1,3-Beta-Glucosidase (Exo-Beta-1,3-Glucanase) (Partial Conserved Domain, Glycosyl Hydrolase Family 13)
peptidase M3A and M3B, thimet/oligopeptidase F
pleckstrin like protein and citron like protein maybe with hypothetical rho1 gdp-gtp exchange activity
A members of the Ras superfamily of small GTPases.
putative siderophore-dependent iron transporter
Shows sequence similarity to SIT1 and ARN1 of S. cerevisiae and MirC of E. nidulans. These are Major facilitator superfamily transporters which act with siderophores in iron uptake. || MFS-MDR transporter belonging to the DHA2 subfamily. These type of MFS transporters are implicated in MDR and secretion of fungal secondary metabolites.
DNA-dependent DNA polymerase beta; DNA repair, DNA replication; base-excision repair; 5'-deoxyribose phosphate (dRP) lyase, Nucleotidyltransferase; DNA polymerase X family
putative glucan 1,3-beta-glucosidase, exo-beta-1,3-glucanase
Glucan 1,3-Beta-Glucosidase (Signal P secreted) (Glycosyl Hydrolase Family 17)
carbamoyl-phosphate synthase (glutamine-hydrolyzing)
This protein contains both WSC and transmembrane domain typical for the receptors in the cell wall integrity pathway and probably is the ortholog of the yeast WSC3 protein.
Multiple inositol polyphosphate phosphatase
putative dual spec /; MgPTP5, putative dual spec
ABC transporter, ABC-B family, MDR (II.2) type. TC3.A.1.201. In the yeasts S. cerevisiae and S. pombe these transporters are involved in secretion of mating pheromone.In other fungi they function as MDR transporters. Shows sequence similarity to AtrH of E. nidulans.
Transmembrane osmosensor requlating the high-osmolarity glycerol response pathway
ADP-ribosylation factor GTPase activator
electron transfer flavoprotein subunit beta
P450 monooxygenase with unknown function. Multiple seq alignment and NJ analysis clustered this model with gi 83768858 (a p450 in a PKS cluster in A. oryzae) and the model ESTEXT_FGENESH2_PG.C_80245. The closest match among characterized p450 was StcB (A
Putative with domains homologous to yeast SFL1 (Heat Shock Factor; HSF1) required for normal cell surface assembly and flocculence.
ABC transporter, ABC-B family, ATM / HMT type. ATM1 is an ABC transporter that is expressed in the mitochondia. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins.
unknown function, similar to GENE ID: 5229019 MGCH7_ch7g1093 | hypothetical protein [Magnaporthe grisea 70-15], predicted secreted; unknown hypothetical prot
putative major facilitator superfamily transporter
Putative Major facilitator superfamily (MFS) transporter. Shows sequence similarity to hypothetical fungal proteins. Contains predicted signal peptide. Predicted membrane localization.
succinate--CoA ligase (GDP-forming) subunit beta
succinate-CoA ligase (GDP-forming); succinyl-CoA synthetase (GDP-forming); succinyl coenzyme A synthetase (guanosine diphosphate-forming); succinate thiokinase; succinic thiokinase; succinyl coenzyme A synthetase; succinate-phosphorylating enzyme; P-enzyme; SCS; G-STK; succinyl coenzyme A synthetase (GDP-forming); succinyl CoA synthetase, a mitochondrial enzyme of the TCA cycle
Similar to beta ketoadipyl CoA thiolase, last step of the ketoadipate pathway. It forms succinyl-CoA and acetyl-CoA. Interestingly a succinyl-CoA synthetase is next to it.
Predicted to be membrane localized. Shows sequence similarity to H+/Ca2+ antiporters. Predicted Cytochrome C heme binding site.
proteasome regulatory particle subunit RPT6
P450 with unknown function. nodorum clustered with genes potentially involved in aromatic compound processing.
HMMPfam hit to Peptidase_S28, Serine carboxypeptidase S28. Has a predicted signal peptide.
ERG6, Delta(24)-sterol C-methyltransferase
Delta(24)-sterol C-methyltransferase, converts zymosterol to fecosterol in the ergosterol biosynthetic pathway by methylating position C-24
A member of the MYST acetyltransferase family similar to the Saccharomyces cerevisiae SAS3 protein
hypothetical protein, unknown function, highly similar to gi|39945264|ref|XP_362169.1| predicted protein [Magnaporthe grisea 70-15]
Acetyl-CoA carboxylase, biotin containing enzyme that catalyzes the carboxylation of acetyl-CoA to form malonyl-CoA; required for de novo biosynthesis of long-chain fatty acids
pleckstrin like protein with G protein interacting region || In yeast this protein is a GDP/GTP exchange protein (GEP) for Rho1p and Rho2p in the cell wall integrity pathway. Also has Rho1 gdp-gtp exchange protein activity. Related to yeast Rom2
pyruvate dehydrogenase E1, alpha subunit
histone acetyltransferase type B catalytic subunit
Putative homolog of the Saccharomyces cerevisiae HAT1 protein, the catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex
fructose-bisphosphatase; hexose diphosphatase; FBPase; fructose 1,6-diphosphatase; fructose 1,6-diphosphate phosphatase; D-fructose 1,6-diphosphatase; fructose 1,6-bisphosphatase; fructose diphosphatase; fructose diphosphate phosphatase; fructose bisphosphate phosphatase; fructose 1,6-bisphosphate 1-phosphatase; fructose 1,6-bisphosphate phosphatase; hexose bisphosphatase; D-fructose-1,6-bisphosphate phosphatase; GO:0005829: cytosol GO:0005737: cytoplasma
P450 with unknown function. Comparison with characterized p450s did not yield highly significant matches
Beta-Glucosidase (Glycosyl Hydrolase Family 3) (Avenicinase-like)
Shows sequence similarity to FET3 and FET5 of S. cerevisiae. These proteins are ferroxidases involved in iron uptake.
Putative Major facilitator superfamily (MFS) transporter. Predicted signal peptide. Predicted membrane localization.
Putative fatty acid omega-hydroxylase. P450 belonging to the Class III (bifunctional P-450)
SAP family cell cycle dependent phosphatase-associated protein
aminophospholipid-translocating P4-type ATPase
Alpha-L-Arabinofuranosidase B (Signal P secreted)
(NAD+); CoA-independent aldehyde dehydrogenase; m-methylbenzaldehyde dehydrogenase; NAD-aldehyde dehydrogenase; NAD-dependent 4-hydroxynonenal dehydrogenase; NAD-dependent aldehyde dehydrogenase; NAD-linked aldehyde dehydrogenase; propionaldehyde dehydrogenase; aldehyde dehydrogenase (NAD)
beta carboxy-cis-cis-muconate lactonizing enzyme, cyloisomerase, CLME2
Enzyme part of the ketoadipate pathway, a degradation route for the utilization of aromatic compounds.
Endo-Beta-1,6-Glucanase (Signal P secreted)
2-oxoglutarate dehydrogenase E1 component
oxoglutarate dehydrogenase (succinyl-transferring); 2-ketoglutarate dehydrogenase; 2-oxoglutarate dehydrogenase; 2-oxoglutarate: lipoate oxidoreductase; 2-oxoglutarate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-succinylating); alpha-ketoglutarate dehydrogenase; alphaketoglutaric acid dehydrogenase; alpha-ketoglutaric dehydrogenase; alpha-oxoglutarate dehydrogenase; AKGDH; OGDC; ketoglutaric dehydrogenase; oxoglutarate decarboxylase; oxoglutarate dehydrogenase; oxoglutarate dehydrogenase (lipoamide)
mitochondrial 37S ribosomal protein MRPS16
ketoacyl synthase domain-containing protein
ketoacyl synthase domain similar to those found in polyketide synthase genes involved in secondary metabolite biosynthesis
putative major intrinsic protein superfamily protein
Putative Major intrinsic protein (MIP) superfamily protein. Shows similarity to Aquaporin-like proteins. Predicted signal peptide. Predicted integral membrane protein.
ABC transporter, ABC-B family, TAP / MDL type. This family consists of mitochondrial ATP-binding cassette proteins involved in iron homeostasis.
MFS-MDR transporter belonging to the DHA2 subfamily. These type of MFS transporters are implicated in MDR and secretion of fungal secondary metabolites.
cdc11 like protein, which possibly forms part of septin ring required for cytokinesis. It contains cell division, GTP binding domain