Zymoseptoria tritici IPO323 chromosome 7, whole genome shotgun sequence.
Zymoseptoria tritici IPO323 (Mycosphaerella graminicola IPO323)
Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes; Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Zymoseptoria.
Finished Genome of the Fungal Wheat Pathogen Mycosphaerella graminicola Reveals Dispensome Structure, Chromosome Plasticity, and Stealth Pathogenesis
Submitted (06-FEB-2020) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (18-MAY-2011) US DOE Joint Genome Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598-1698, USA
PROVISIONAL REFSEQ: This record has not yet been subject to final\nNCBI review. The reference sequence is identical to CM001202.\nURL -- http://www.jgi.doe.gov/Mgraminicola\nJGI Project ID: 4000758\nThe DNA was provided by G.H.J. Kema (gert.kema@wur.nl)\nThe strain is available from Fungal Biodiversity Center,\nhttp://www.cbs.knaw.nl\nContacts: Stephen B. Goodwin (sgoodwin@purdue.edu)\n Gert H. J. Kema (gert.Kema@wur.nl)\n Igor Grigoriev (ivgrigoriev@lbl.gov)\nAssembly and annotation done by JGI.\n\n##Genome-Assembly-Data-START##\nAssembly Method :: JAZZ v. 1.0\nAssembly Name :: MYCGR v2.0\nGenome Coverage :: 8.9X\nSequencing Technology :: Sanger\n##Genome-Assembly-Data-END##\n\n##Metadata-START##\nOrganism Display Name :: Mycosphaerella graminicola IPO323\nGOLD Stamp ID :: Gi00795\n##Metadata-END##\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: INSDC submitter\nAnnotation Status :: Full annotation\nAnnotation Pipeline :: Eukaryotic Annotation Propagation Pipeline\n##Genome-Annotation-Data-END##
culture from epitype of Zymoseptoria tritici
P450 monooxygenase with unknown function. Multiple seq alignment and NJ analysis clustered this model with E_GW.10.85.1. Comparison with characterized p450s did not yield significant matches
major facilitator superfamily transporter
MFS-MDR transporter involved in pleiotropic drug resistance and fungicide sensitivity. Belonging to DHA2(14 spanner), TC2.A.1.3 family.
Secreted . Acidic (predicted pI 4.66) 441 aa protein. In mammal pathogenic fungi aspartyl protease is involved in pathogenesis
II like protein, may be involved in the hydrolysis of asparagine to aspartic acid and ammonia.
The ortholog of highly conserved yeast Stt4 which is a that functions in the cell wall integrity pathway.
Glucan 1,3-Beta-Glucosidase (Exo-Beta-1,3-Glucanase) (Glycosyl Hydrolase Family 17, Partial Conserved Domain (Signal P secreted)
No reliable hits with protein databases, neither with hypothetical (not significant). Probable M graminicola specific protein (novel gene). unknown function.
probably secreted. It is not possible to predict if it belong to a highly divergent family (it matches with low homology with some fungal hypothetical proteins) or it is a M. graminicola specific protein. Unknown function.
isocitrate dehydrogenase [NAD] subunit 1
isocitrate dehydrogenase (NAD+); isocitric dehydrogenase; beta-ketoglutaric-isocitric carboxylase; isocitric acid dehydrogenase; NAD dependent isocitrate dehydrogenase; NAD isocitrate dehydrogenase; NAD-linked isocitrate dehydrogenase; NAD-specific isocitrate dehydrogenase; NAD isocitric dehydrogenase; isocitrate dehydrogenase (NAD); IDH (ambiguous); nicotinamide adenine dinucleotide isocitrate dehydrogenase, MITOCHONDRIAL PRECURSOR
Conserved eukaryotic protein, conatining DUF 396 domain (Domain of unknown function).DUF396 is a family of conserved eukaryotic transmembrane proteins
putative 4-hydroxyphenylpyruvate dioxygenase
This model has similaries with: 3-dehydroshikimate dehydratase; 4-hydroxyphenylpyruvate dioxygenase; quinate 5-dehydrogenase (qa-4).
eukaryotic translation initiation factor 2 subunit gamma
ABC transporter, ABC-C family. MRP type. TC3.A.1.208.These transporters mainly transport conjugated compounds and can be involved in metal resistance. Gene located in area with models implicated in protein turnover/ posttranslational modifications.
1,2-Alpha-Mannosidase (Glycosyl Hydrolase 47)
proteasome core particle subunit alpha 7
1,2-Alpha-Mannosidase (Signal P anchor) (Glycosyl Hydrolase 47)
putative dual spec / tyrosine protein phosphatase 6
Histone methyltransferase, subunit of the COMPASS complex
Triacylglycerol hydrolase, putative precursor. Secreted. Lipase; related to sterol esterase. Probable biotechnological application for flavour development in cheese and for whole-cell biocatalysts in biodiesel-fuel production.
alpha/beta hydrolase BEM46/Esterase/lipase/thioesterase
Predicted alpha/beta hydrolase BEM46; Esterase/lipase/thioesterase; predicted cytosolic and probably associated (bound?) to a membrane (nondetermined)
P450 monooxygenase with unknown function.
putative major facilitator superfamily transporter
MFS-MDR transporter belonging to the DHA2 subfamily. These type of MFS transporters are implicated in MDR and secretion of fungal secondary metabolites.
Mevalonate kinase, acts in the biosynthesis of isoprenoids and sterols, including ergosterol, from mevalonate
Shows sequence similarity to SFK1 of yeasts. SFK1 is a Plasma membrane protein that may act together with or upstream of Stt4p to generate normal levels of the essential phospholipid PI4P, at least partially mediates proper localization of Stt4p to the plasma membrane.
Related to yeast Bmh2 and is a 14-3-3 protein that can bind proteins and DNA, involved in regulation of many processes including exocytosis and vesicle transport, Ras/MAPK signaling during pseudohyphal development, rapamycin-sensitive signaling.
P450 putatively acting on a cyclic terpene compound or moiety. p450 similar to GA14-synthase (gibberellin biosynthesis) and other p450s found next to terpene biosynthetic genes in other fungi. Similar to E_GW.8.233.1. Similarities were assessed both by multiple and local sequence alignments.
Basic Protein (pI 8.38); predicted plasmatic membrane-bound with extracelelluar face. Not clear if it belongs to a fungal highly divergent protein family (poor homology with fungal hypothetical proteins) or it is M. graminicola specific.
Fatty acid transporter protein. AMP-dependent synthetase and ligase
Beta-Glucosidase (Glycosyl Hydrolase Family 3)
serine/threonine protein kinase, CMGC family, CDC2/CDK subfamily
phosphopyruvate hydratase; enolase; 2-phosphoglycerate dehydratase; 14-3-2-protein; nervous-system specific enolase; phosphoenolpyruvate hydratase; 2-phosphoglyceric dehydratase; 2-phosphoglycerate enolase; gamma-enolase
Secreted FAD-dependent oxidoreductase; FAD linked oxidase, N-terminal; similar to oxygen oxidoreductase. Involved in electron transport, energy production and conversion.
P450 with unknown function. This model is located close to a putative geranylgeranyl transferase and genes potentially involved in the processing of aromatic compounds. Multiple seq alignment and NJ analysis clustered this model with E_GW.10.660.1. Comparison with characterized p450s did not yield significant matches.
Conserved fungal protein (significant homology with fungal hypothetical proteins with unknown function). Predicted plasmatic, integral small protein
SNF2 family DNA-dependent ATPase domain-containing protein
GLN1 - amino acid and polyamine transporter
Alpha-1,6-Mannosidase (Glycosyl Hydrolase 76)
chromosome condensation complex Condensin, subunit H
Predicted mitochondrial, soluble (not defined if matrix or intermembranne space). No hits with protein databases, neither with hypothetical. Probable M graminicola specific protein (novel gene). unknown function.
hypothetical protein, contains DnaJ molecular chaperone domain; J-domains are associated with hsp70 heat-shock system. Similar to GENE ID: 3508811 AFUA_6G06610 | endoplasmic reticulum DnaJ domain protein Erj5, putative [Aspergillus fumigatus Af293]; although independent kNN analysis localize it to mithocondria(k:13 of 27).
Putative acyltransferase 3. Predicted signal peptide. Predicted membrane localization.
Ca2+-modulated nonselective cation channel polycystin
FKBP peptidyl-prolyl cis-trans isomerase
FKBP-type peptidyl-prolyl cis-trans isomerase
geranylgeranyl transferase type 2 subunit beta
P450 with unknown function. This model is clustered with a geranyl geranyltransferase type II, beta subunit and genes potentially involved in the degradation of aromatic compounds
related to calcium intracellular signaling
Lanosterol 14-alpha-demethylase, catalyzes the C-14 demethylation of lanosterol to form 4,4''-dimethyl cholesta-8,14,24-triene-3-beta-ol in the ergosterol biosynthesis pathway; target for azole fungicides
Putative fatty acid omega-hydroxylase. P450 belonging to the Class III (bifunctional P-450)
succinate dehydrogenase (ubiquinone) iron-sulfur subunit
succinate dehydrogenase (ubiquinone); succinic dehydrogenase; complex II; menaquinol: fumarate oxidoreductase; fumarate reductase complex (that is FRD, involved in anaerobic respiration, repressed in aerobic respiration); succinate dehydrogenase complex (i.
ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
Beta-Fructosidase (Invertase) (Glycosyl Hydrolase Family 32)
MgMnd1 shows a domain structure described in the InterPro database as characteristic of the Mnd1 family. This family of proteins includes MND1 from S. cerevisiae. The mnd1 protein forms a complex with hop2 to promote homologous chromosome pairing and meiotic double-strand break repair.
Protein overlapping with rRNA (MYCGRDRAFT_45585, EGP85764.1) was converted to a misc_feature.
Protein overlapping with rRNA (MYCGRDRAFT_45280, EGP86035.1) was converted to a misc_feature.
Protein overlapping with rRNA (MYCGRDRAFT_45610, EGP85765.1) was converted to a misc_feature.
Protein overlapping with rRNA (MYCGRDRAFT_45560, EGP86034.1) was converted to a misc_feature.
Protein overlapping with rRNA (MYCGRDRAFT_30987, EGP86033.1) was converted to a misc_feature.
Protein overlapping with rRNA (MYCGRDRAFT_44515, EGP86032.1) was converted to a misc_feature.
Protein overlapping with rRNA (MYCGRDRAFT_45273, EGP86031.1) was converted to a misc_feature.
Protein overlapping with rRNA (MYCGRDRAFT_74248, EGP86030.1) was converted to a misc_feature.
Protein overlapping with rRNA (MYCGRDRAFT_30868, EGP85766.1) was converted to a misc_feature.
Protein overlapping with rRNA (MYCGRDRAFT_45182, EGP85767.1) was converted to a misc_feature.
Protein overlapping with rRNA (MYCGRDRAFT_74252, EGP86029.1) was converted to a misc_feature.
Protein overlapping with rRNA (MYCGRDRAFT_45195, EGP85768.1) was converted to a misc_feature.
Protein overlapping with rRNA (MYCGRDRAFT_86961, EGP85769.1) was converted to a misc_feature.
Protein overlapping with rRNA (MYCGRDRAFT_44591, EGP86028.1) was converted to a misc_feature.
Protein overlapping with rRNA (MYCGRDRAFT_30981, EGP86027.1) was converted to a misc_feature.
Protein overlapping with rRNA (MYCGRDRAFT_44923, EGP86026.1) was converted to a misc_feature.
Protein overlapping with rRNA (MYCGRDRAFT_45572, EGP86025.1) was converted to a misc_feature.
Protein overlapping with rRNA (MYCGRDRAFT_74254, EGP86024.1) was converted to a misc_feature.
Protein overlapping with rRNA (MYCGRDRAFT_30869, EGP85770.1) was converted to a misc_feature.
Protein overlapping with rRNA (MYCGRDRAFT_45130, EGP85771.1) was converted to a misc_feature.
Protein overlapping with rRNA (MYCGRDRAFT_100832, EGP86023.1) was converted to a misc_feature.
Protein overlapping with rRNA (MYCGRDRAFT_44699, EGP85772.1) was converted to a misc_feature.
putative FRE ferric reductase-like transmembrane component
Shows sequence similarity to FRE proteins of S. cerevisiae. These proteins are involved in iron uptake. They are ferroxidase(FET)-dependent reductases.
HMMPfam hit to Peptidase_S28, Serine carboxypeptidase S28. Seems to lack a signal peptide.
Carbohydrate metabolism: Glycoside hydrolasesare a widespread group of enzymes which hydrolyze the glycosdic bond between two or more carbohydrates or between a carbohydrate and a non- carbohydrate moiety. This particular sequence has a putative conserved 3N terminal domain known as 'Glyco hydro 3.
Not part of the signal peptidase complex
T-type voltage-gated Ca2+ channel, alpha1I subunit
Ca2+ channel pore-forming alpha1I subunit
Endo-Beta-1,4-Xylanase (Precursor Possibly) (Glycosyl Hydrolase Family 10) (Signal P secreted)
Endo-Beta-1,4-Xylanase (Glycosyl Hydrolase Family 10) (Signal P secreted) (Has precursor possibly)
predicted involved in secondary metabolite biosynthesis
ABC-G family, PDR type, TC no: 3.A.1.205. No known function, expressed during interaction
P450 putatively acting on a polyketide metabolite. This model appear to be part of a PKS cluster. Comparison with characterized p450s did not yield highly significant matches. Multiple seq alignment and NJ analysis clustered this model with the following models: GW.1.2615.1 and GW.2.467.1 (in a PKS cluster).