Zymoseptoria tritici IPO323 chromosome 10, whole genome shotgun sequence.
Zymoseptoria tritici IPO323 (Mycosphaerella graminicola IPO323)
Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes; Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Zymoseptoria.
Finished Genome of the Fungal Wheat Pathogen Mycosphaerella graminicola Reveals Dispensome Structure, Chromosome Plasticity, and Stealth Pathogenesis
Submitted (06-FEB-2020) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (18-MAY-2011) US DOE Joint Genome Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598-1698, USA
PROVISIONAL REFSEQ: This record has not yet been subject to final\nNCBI review. The reference sequence is identical to CM001205.\nURL -- http://www.jgi.doe.gov/Mgraminicola\nJGI Project ID: 4000758\nThe DNA was provided by G.H.J. Kema (gert.kema@wur.nl)\nThe strain is available from Fungal Biodiversity Center,\nhttp://www.cbs.knaw.nl\nContacts: Stephen B. Goodwin (sgoodwin@purdue.edu)\n Gert H. J. Kema (gert.Kema@wur.nl)\n Igor Grigoriev (ivgrigoriev@lbl.gov)\nAssembly and annotation done by JGI.\n\n##Genome-Assembly-Data-START##\nAssembly Method :: JAZZ v. 1.0\nAssembly Name :: MYCGR v2.0\nGenome Coverage :: 8.9X\nSequencing Technology :: Sanger\n##Genome-Assembly-Data-END##\n\n##Metadata-START##\nOrganism Display Name :: Mycosphaerella graminicola IPO323\nGOLD Stamp ID :: Gi00795\n##Metadata-END##\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: INSDC submitter\nAnnotation Status :: Full annotation\nAnnotation Pipeline :: Eukaryotic Annotation Propagation Pipeline\n##Genome-Annotation-Data-END##
culture from epitype of Zymoseptoria tritici
phosphatidylinositol 4-kinase, PI signaling pathway
Chromatin remodeling complex subunit B; probable ortholog of yeast SWI3 & RSC8; components of the SWI/SNF and RSC chromatin remodeling complexes.
SNF2 family DNA-dependent ATPase domain-containing protein
Adenylate cyclase-associated protein (CAP); In S. cerevisiae CAP interacts with Ras and adenylate cyclase to increase cAMP levels under specific environmental conditions. Related to yeast Srv2.
Probable sulphate transporter. There are four sulphate transporter-like proteins within this species.
UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE
Forms part of the tubulin complex, which polymerises to form tubulin
ribose-phosphate PYROPHOSPHOKINASE pyrophosphate synthetase
ribose-phosphate diphosphokinase; ribose-phosphate pyrophosphokinase; PRPP synthetase; phosphoribosylpyrophosphate synthetase; PPRibP synthetase; PP-ribose P synthetase; 5-phosphoribosyl-1-pyrophosphate synthetase; 5-phosphoribose pyrophosphorylase; 5-phosphoribosyl-alpha-1-pyrophosphate synthetase; phosphoribosyl-diphosphate synthetase; phosphoribosylpyrophosphate synthase; pyrophosphoribosylphosphate synthetase; ribophosphate pyrophosphokinase; ribose-5-phosphate pyrophosphokinaseEDD
eukaryotic translation initiation factor 2 subunit alpha
phosphate-repressible phosphate permease
putative FRE ferric reductase-like transmembrane component
Shows sequence similarity to FRE proteins of S. cerevisiae. These proteins are involved in iron uptake. They are ferroxidase(FET)-dependent reductases.
Has EST support. similar est in H. jecorina
Endo-Beta-1,4-Glucanase (Glycosyl Hydrolase Family 12) (Signal P Secreted); Cellulase; Carboxymethylcellulase
guanine-nucleotide dissociation stimulator CDC25
Beta-Galactosidase (Lactase) (Glycosyl Hydrolase 2)
mitochondrial 54S ribosomal protein MRPL51
Similar to Saccharomyces cerevisiae DOT1, a
SWI/SNF chromatin remodeling complex component
SNF2 family DNA-dependent ATPase similar to Saccharomyces cerevisiae YFR038W, the null mutant displays increased levels of spontaneous Rad52 foci
P450 similar to GA14-synthase (gibberellin biosynthesis) and other P450s found next to terpene biosynthetic genes in other fungi. Similarity was assessed by multiple and local sequence alignments. This gene is located in an area containing a geranylgeranyl pyrophosphate synthase and a hybrid PKS-PS.
Geranylgeranyl Diphosphate Synthase 3, possibly associated with a terpenoid secondary metabolism gene cluster
P450 with unknown function. This model is located next to a geranylgeranyl pyrophosphate synthase and a hybrid PKS/PS. Multiple seq alignment and NJ analysis clustered this model with gw.4.1100.1 (a P450 located next to a 1-module NRPS), gi 46114844 (a pP450 located close to a NRPS in G.
putative Het-C2 heterokaryon incompatibility
[Domain]GLTP (PF08718)Glycolipid transfer protein (GLTP) is a cytosolic protein that catalyses the intermembrane transfer of glycolipids such as glycosphingolipids, glyceroglycolipids, and possibly glucosylceramides, but not of phospholipids.[Function] putative role in plycosphingolipid and sphingolipid metabolism and regulation of cellular stress responses.
putative hybrid polyketide synthetase/nonribosomal peptide synthetase
putative hybrid polyketide synthase/nonribosomal peptide synthetase involved in secondary metabolite biosynthesis
putative major facilitator superfamily transporter
MFS-MDR transporter belonging to the DHA2 subfamily. These type of MFS transporters are implicated in MDR and secretion of fungal secondary metabolites. Neighbouring HPS1 (a hybrid polketide synthetase / NRPS) and a putative isoflavone reductase
putative aminophospholipid-translocating P4-type ATPase
gamma tubulin complex associated-like protein
Similar to gamma tubulin complex associated protein
Major facilitator superfamily, membrane localised
P450 potentially involved in the biosynthesis of a polyketide
similar to S. cerevisiae FRE proteins, involved in Iron uptake, ferroxidase (FET) dependent
Similar to, last step of the ketoadipate pathway.
Hypothetical MAP kinase kinase (MAPKK) involved in the osmosensing signal-transduction pathway, activated under severe osmotic
transporter auxin efflux carrier-like protein
transporter - auxin efflux carrier-like with six predicted transmembrane regions
Hypothetical that is related to DNA binding component of the SBF complex (Swi4p-Swi6p) in S. cerevisiae.
Similar to Saccharomyces cerevisiae SPT4 protein which forms a complex with Spt5p and mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing
MgPPT1, serine threonine phosphatase 2A catalytic sub-unit like protein
serine threonine phosphatase 2A catalytic sub-unit like protein
1,2-Alpha-Mannosidase (Glycosyl Hydrolase Family 47) (Signal P secreted)
Alpha-Glucosidase (Signal P secreted) (Glycosyl hydrolase Family 31)
Ca2+-modulated nonselective cation channel polycystin
evolved in intracellular signal and calcium concentration changes
(NAD+); isocitric dehydrogenase; beta-ketoglutaric-isocitric carboxylase; isocitric acid dehydrogenase; NAD dependent isocitrate dehydrogenase; NAD isocitrate dehydrogenase; NAD-linked isocitrate dehydrogenase; NAD-specific isocitrate dehydrogenase; NAD isocitric dehydrogenase; isocitrate dehydrogenase (NAD); IDH (ambiguous); nicotinamide adenine dinucleotide isocitrate dehydrogenase
dihydrolipoyllysine-residue acetyltransferase; acetyl-CoA:dihydrolipoamide S-acetyltransferase; dihydrolipoamide S-acetyltransferase; dihydrolipoate acetyltransferase; dihydrolipoic transacetylase; dihydrolipoyl acetyltransferase; lipoate acetyltransferase; lipoate transacetylase; lipoic acetyltransferase; lipoic acid acetyltransferase; lipoic transacetylase; lipoylacetyltransferase; thioltransacetylase A; transacetylase X
malic dehydrogenase; L-malate dehydrogenase; NAD-L-malate dehydrogenase; malic acid dehydrogenase; NAD-dependent malic dehydrogenase; NAD-malate dehydrogenase; NAD-malic dehydrogenase; malate (NAD) dehydrogenase; NAD-dependent malate dehydrogenase; NAD-specific malate dehydrogenase; NAD-linked malate dehydrogenase; MDH; L-malate-NAD+ oxidoreductase, MITOCHONDRIAL
translocase of outer mitochondrial membrane complex, subunit TOM41
Translocase of outer mitochondrial membrane complex, subunit TOM40
putative alpha glucoside I/Mannosyl oligosaccharide glucosidase
Alpha- Glucoasidase (Glycosyl Hydrolase Family 63)
major facilitator superfamily transporter
MFS-MDR transporter belonging to the DHA2 subfamily, TC2.A.1.3 family. These type of MFS transporters are implicated in MDR and secretion of fungal secondary metabolites.
ABC transporter, ABC-A family. Probably belonging to the AOH type. This family has no homologs in yeast. The ABCA subfamily is involved in lipid transport. Members of this subfamily are exclusively found in eukaryotes and display an IM-ABC or an (IM-ABC)2 organization, similar to that of the MDR family of exporter.
. Probable component of spindle pole body; . probable component of spindle pole body
proteasome core particle subunit alpha 5
hypothetical protein, 4HBT like, (4-hydroxybenzoyl-CoA thioesterase), similar to gi|169597491|ref|XP_001792169.1| hypothetical protein SNOG_01531 Phaeosphaeria nodorum SN15. Predicted mitochondrial location.
ferric reductase-like transmembrane component
Shows some sequence similarity to FRE1 of S. cerevisiae. Ferroxidase (FET)-dependent reductase.
putative siderophore-dependent iron transporter
Shows sequence similarity to ENB1 and ARN1 of S. cerevisiae and MirB of E. nidulans. These are Major facilitator superfamily transporters which act with siderophores in iron uptake.
electron transfer flavoprotein subunit alpha, mitochondrial
Mitogen-activated protein kinase (MAPK), Osmosensing MAPK, the orthologous of Hog1 in Saccharomyces cervisiae involved in High Osmolarity Glycerol pathway.
Shows sequence similarity to SIT1 and ARN1 of S. cerevisiae and MirA and mirB of E. nidulans. These are Major facilitator superfamily transporters which act with siderophores in iron uptake
signaling protein FUS1 fusion associated to cell wall integrity
succinate dehydrogenase cytochrome B subunit
succinate dehydrogenase (ubiquinone); succinic dehydrogenase; complex II; menaquinol: fumarate oxidoreductase; fumarate reductase complex (that is FRD, involved in anaerobic respiration, repressed in aerobic respiration); succinate dehydrogenase complex (i.
alfa-arabinofuranosidase-a precursor, related to protein 76302
P450 potentially involved in the biosynthesis of a polyketide. This model is located near a fumonisin-like PKS
MFS-MDR transporter belonging to the DHA2 subfamily. These type of MFS transporters are implicated in MDR and secretion of fungal secondary metabolites. Close to polyketide synthase and trichothecene hydoxylase, and cytP450
predicted; in predicted gene cluster with PKS5 and other genes potentially involved in sphinganine-analog mycotoxin biosynthesis
serine palmitoyl CoA transferase subunit LcbA
predicted involved in secondary metabolite biosynthesis
P450 with unknown function. This model is physically clustered with a fumonisin-like PKS, and the models estExt_fgenesh2_pg.C_120477 (unknown function, similar to ABA3), estExt_fgenesh2_pm.C_120135 (p450, very similar to ABA2). Multiple seq alignment and NJ analysis clustered this model with Fum12 (fumonisin biosynthesis), gi 39943642 (a p450 located adjacent to a terpene cyclase in M.
Very similar to ABA3 which is part of the abscisic acid gene cluster in B. cinerea.
This p450 could be part of a terpene biosynthetic route (abscisic acid?). This model is physically clustered with the models estExt_fgenesh2_pg.C_120477 (unknown function, similar to ABA3), E_GW.12.606.1 (p450, similar to Fum12). Multiple seq alignment and NJ analysis cluster this model with the model E_GW.8.216.1 and with gi 51490962 (or ABA2, ABA biosynthasis in B.
Protocatechuate 3,4-dioxygenase, aromatic-ring-cleaving enzyme. Enzyme part of the ketoadipate pathway, a degradation route for the utilization of aromatic compounds.
Neutral Trehalase (Alpha,Alpha-Trehalase) (Glycosyl Hydrolase Family 37) (Signal P secreted)
Engo-Beta-1,4-Glucanase (Cellulase) (Glycosyl Hydrolase Family 45) (No Signal P secretion prediction)
hypothetical protein, unknown function, predicted extracellular (kNN), might be distantly related to carboxypeptidase Y inhibitor from Saccharomyces cerevisiae
receptor-activated Ca2+-permeable cation channel
Receptor-activated Ca2+-permeable cation channels (STRPC family)