Zymoseptoria tritici IPO323 chromosome 11, whole genome shotgun sequence.
Zymoseptoria tritici IPO323 (Mycosphaerella graminicola IPO323)
Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes; Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Zymoseptoria.
Finished Genome of the Fungal Wheat Pathogen Mycosphaerella graminicola Reveals Dispensome Structure, Chromosome Plasticity, and Stealth Pathogenesis
Submitted (06-FEB-2020) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (18-MAY-2011) US DOE Joint Genome Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598-1698, USA
PROVISIONAL REFSEQ: This record has not yet been subject to final\nNCBI review. The reference sequence is identical to CM001206.\nURL -- http://www.jgi.doe.gov/Mgraminicola\nJGI Project ID: 4000758\nThe DNA was provided by G.H.J. Kema (gert.kema@wur.nl)\nThe strain is available from Fungal Biodiversity Center,\nhttp://www.cbs.knaw.nl\nContacts: Stephen B. Goodwin (sgoodwin@purdue.edu)\n Gert H. J. Kema (gert.Kema@wur.nl)\n Igor Grigoriev (ivgrigoriev@lbl.gov)\nAssembly and annotation done by JGI.\n\n##Genome-Assembly-Data-START##\nAssembly Method :: JAZZ v. 1.0\nAssembly Name :: MYCGR v2.0\nGenome Coverage :: 8.9X\nSequencing Technology :: Sanger\n##Genome-Assembly-Data-END##\n\n##Metadata-START##\nOrganism Display Name :: Mycosphaerella graminicola IPO323\nGOLD Stamp ID :: Gi00795\n##Metadata-END##\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: INSDC submitter\nAnnotation Status :: Full annotation\nAnnotation Pipeline :: Eukaryotic Annotation Propagation Pipeline\n##Genome-Annotation-Data-END##
culture from epitype of Zymoseptoria tritici
required for posttranscriptional gene silencing and RNA interference RNA processing and modification
blue-light-activated transcription factor
White collar protein-encoding gene MgWCO1. Predicted product:.
Chitinase, Class V (Glycosyl Hydrolase Family 18)(Signal P secreted)
Mitogen-activated protein kinase kinase kinase (MAPKKK) acting in the cell wall integrity signaling pathway
HMMPfam hit to Peptidase_S28, Serine carboxypeptidase S28. Has a predicted signal peptide
Beta-xylosidase, Glycosyl hydrolases family 43 (PF04616)
p450 potentially involved in the degradation of fatty acids and/or alkanes. Multiple seq alignment followed by NJ analysis clustered this model with gi41079162; gi3395458, gi29469881, gi70984521 (alkane or fatty acids monooxygenases), and the models GW.2.447.1, E_GW.6.936.1, ESTEXT_FGENESH2_PG.C_40295 ESTEXT_FGENESH2_PM.C_50060, ESTEXT_GWP_GW1.C_90605.
putative acetyl xylan Esterase/Acetylesterase
Acetyl Xylan Esterase/Acetylesterase (Signal P secreted)
Ca2+-modulated nonselective cation channel polycystin
conserved hypothetical protein, TIM phosphate binding superfamily, related to L-lactate dehydrogenase
serine palmitoyl CoA transferase subunit LcbA
putative serine palmitoyl coA transferase subunit LcbA, = Lcb1 = regulatory domain
Putative homolog of Saccharomyces cerevisiae ARP4; a nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes
hydrophobin-like. Four cysteines in addition to hydrophobin core.
hypothetical protein, unknown function, probably related to PRK06849
Hydrophobin. Similar to class II hydrophobins
protein disulfide with oxidoreductase activity
Hypothetical peroxisome located protein with 3 conserved domains: one domain has similarity to Tyrosinase (=catechol oxidase; diphenol oxidase)and the other two domains have similarity to NahD -2 hydroxychromene -2 carboxylate isomerase. These latter domains are also similar to DSBA-like thioredoxins.The tyrosinase family also includes polyphenol oxidases and some hemocyanins which bind 2 copper ions via 2 sets of 3 histidines.
Related to yeast Msn5 that is a Karyopherin protein involved in nuclear import and export of several proteins including Swi6 and Far1 transcription factors in MAPK pathways
P450 potentially involved in the biosynthesis of a polyketide. This model is located about 60K from a PKS.
IPKP58 dsRNA-activated protein kinase inhibitor
Involved in defence mechanisms. In animals P58 is recruited by the influenza virus to limit dsRNA-activated protein kinase inhibitor (PKR)activity; in plants P58 seems to be required by viruses for virulence and therefore functions as a susceptibility factor.
Non-transporter ABC protein belonging to the SMC type. These proteins contain motifs resembling the Walker A and Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. Eukaryotic SMC6 proteins; SMC proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains.
gene highly similar to those involved in fungal melanin biosynthesis; contains conserved domains typically found in PKSs that synthesize fungal pigments
1,2-Alpha-Mannosidase (Glycosyl Hydrolase Family 47) (May be membrane bound-no signal p prediction)
similarity to yeast and human enzyme type
phosphotyrosine-specific protein phosphatase
Phosphotyrosine-specific protein phosphatase related to yeast Ptp1 that dephosphorylates a broad range of substrates in vivo, including Fpr3; localized to the cytoplasm and the mitochondria
homology to co-factor-independent enzymes conserved in other filamentous fungi
Oligopeptide transporter superfamily protein, contains PFAM PF03169 and 15 predicted transmembrane regions
ARID/BRIGHT DNA-binding domain-containing protein
ABC-G family, PDR type, TC no 3.A.1.205. Capable of pleiotropic drug resistance and involved in pathogenesis on wheat.
VanZ domain hypothetical protein product, function unknown; VanZ superfamily, probably COG4767 or COG5652, could be related to antibiotic defence mechanism
Putative homolog of Saccharomyces cerevisiae SPT7, a subunit of the SAGA transcriptional regulatory complex
receptor-activated Ca2+-permeable cation channel
Receptor-activated Ca2+-permeable cation channels (STRPC family)
involved in oxidative protein folding in the ER probably by the formation and isomerization of disulfide bonds in newly sythesized proteins
putative N-acetylglucosaminyltransferase subunit
putative Phosphatidylinositol N-acetylglucosaminyltransferase subunit, integral plasma membrane
Conserved hypothetical protein, highly similar to hypothetical protein SNOG_12106 [Phaeosphaeria nodorum SN15 (gi|169617852|ref|XP_001802340.1). Unknown function, predicted integral to plasma membrane.
MgHop2p shows a domain structure described in the InterPro database as characteristic of a protein family that consists of several eukaryotic TBP-1 interacting protein (TBPIP) sequences. This family of proteins includes Hop2p from S. cerevisiae, and Meu13 from Schizosaccharomyces pombe.
phosphatidylinositol-4-phosphate 5-kinase
Endo-Beta-1,3(4)-glucanase/Mix-Linked Glucanase (Signal P secreted)
This protein contains both WSC and transmembrane domain typical for the receptors in the cell wall integrity pathway and probably is the ortholog of the yeast WSC3 protein.
dihydrolipoyllysine-residue succinyltransferase
dihydrolipoyllysine-residue succinyltransferase;dihydrolipoamide S-succinyltransferase; dihydrolipoamide succinyltransferase; dihydrolipoic transsuccinylase; dihydrolipolyl transsuccinylase; dihydrolipoyl transsuccinylase; lipoate succinyltransferase (Escherichia coli); lipoic transsuccinylase; lipoyl transsuccinylase; succinyl-CoA:dihydrolipoamide S-succinyltransferase; succinyl-CoA:dihydrolipoate S-succinyltransferase COMMENT: A multimer (24-mer) of this enzyme forms the core of the multienzyme complex, and binds tightly both, oxoglutarate dehydrogenase (succinyl-transferring) and, dihydrolipoyl dehydrogenase.
Histone 2A, core histone required for chromatin assembly and chromosome function
Histone H2B, core histone required for chromatin assembly and chromosome function
Putative homolog of Saccharomyces cerevisiae RSC1 and 2, two of 15 subunits of the Remodel the Structure of Chromatin (RSC) complex; has two bromodomains and a BAH domain
Beta-Fructofuranosidase (Invertase) (Glycosyl hydrolase Family 32)
CMK1 Ca2+/calmodulin-dependent protein kinase
Ca2+/calmodulin-dependent protein kinase
similar to hydrophobic surface binding protein B Aspergillus oryzae (gi|83017070|dbj|BAE53530.1|); and antigenic cell wall galactomannoprotein Aspergillus fumigatus (gi|70981680|ref|XP_746369.1|)
Predicted; contains 30 kDa and 33 kDa sub units. WoLF PSORT anlysis indicates that this is secreted extracellularly, however the sequence terminates with endoplasmic reticulum targeting sequence HDEL; HDEL is also found in other fungi (Saccharomyces cervisiae) and plants.
similar to protein EPD1 precursor Aspergillus terreus (GENE ID: 4317549 ATEG_03277).
Histidine kinase osmosensor that regulates the Slt2 MAP kinase pathway and contains two transmembrane domains and an tracellular kinase domain.
nicotinate-nucleotide pyrophosphorylase (carboxylating)
Probable sulphate transporter 2, Note there are four sulphate transporter-like proteins in this species.
transcription initiation factor TFIID, subunit TAF5
Subunit (90 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification
Putative mitochrondrial membrane protein without transmembrane domain; no putative conserved domains detected, no hits from blast. EST support indicates may be novel gene.
No reliable hits with protein databases, neither with hypothetical (not significant). Probable M graminicola specific protein (novel gene). unknown function.