Aspergillus fumigatus Af293 chromosome 8, whole genome shotgun sequence.
Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus; Aspergillus subgen. Fumigati.
Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus
Erratum:[Nature. 2006 Jan 26;439(7075):502. Lafton, Anne [corrected to Lafon, Anne]]
Submitted (15-APR-2022) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (20-MAY-2005) The Institute for Genomic Research, 9712 Medical Center Dr, Rockville, MD 20850, USA
PROVISIONAL REFSEQ: This record has not yet been subject to final\nNCBI review. The reference sequence is identical to CM000176.\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: INSDC submitter\nAnnotation Status :: Full annotation\nAnnotation Pipeline :: Eukaryotic Annotation Propagation Pipeline\n##Genome-Annotation-Data-END##
encoded by transcript AFUA_8G00100A; similar to cytoplasmic aspartyl-tRNA synthetase, homodimeric enzyme that catalyzes the specific aspartylation of tRNA(Asp); class II aminoacyl tRNA synthetase; binding to its own mRNA may confer autoregulation; Dps1p (GI:6323011) [Saccharomyces cerevisiae]
oxidoreductase, 2OG-Fe(II) oxygenase family, putative
encoded by transcript AFUA_8G00110A; similar to GB:CAG67668.1: putative oxidoreductase {Acinetobacter sp. ADP1;}
nonribosomal brevianamide peptide synthase FtmA
encoded by transcript AFUA_8G00170A; identical to nonribosomal peptide synthase (GI:70983319) [Aspergillus fumigatus Af293] PMID: 16755625 similar to nonribosomal peptide synthase; NRPS1 (GI:32264582) [Alternaria brassicae] PMID: 14727058
encoded by transcript AFUA_8G00190A; similar to SP:O13317: Isotrichodermin C-15 hydroxylase, Cytochrome P450 65A1 [Fusarium sporotrichioides] similar to trichothecene C-15 hydroxylase (GI:21429284) [Gibberella zeae] PMID: 12080147
encoded by transcript AFUA_8G00200A; similar to GB:AAD32742.1: MmcR [Streptomyces lavendulae]
dimethylallyl tryptophan synthase FtmPT1
encoded by transcript AFUA_8G00210A; similar to dimethylallyltryptophan synthase long isoform (GI:32402654) [Claviceps purpurea]
encoded by transcript AFUA_8G00220A; similar to GB:CAE76231.1: O-methylsterigmatocystin oxidoreductase [Neurospora crassa]
phytanoyl-CoA dioxygenase family protein
encoded by transcript AFUA_8G00230A; contains a PhyH domain similar to toxin biosynthesis gene Fum3p (GI:11035010) [Gibberella moniliformis] PMID: 11728154
encoded by transcript AFUA_8G00240A; similar to GB:CAA75565.1: cytochrome P450 monooxygenase [Gibberella fujikuroi]
dimethylallyl tryptophan synthase, putative
encoded by transcript AFUA_8G00250A; similar to dimethylallyltryptophan synthase long isoform DmaW (GI:32402654) [Claviceps purpurea]
encoded by transcript AFUA_8G00260A; similar to Ankyrin 1; Erythrocyte ankyrin; Ankyrin R (Swiss-Prot:P16157) [Homo sapiens]
encoded by transcript AFUA_8G00280A; similar to GB:BAC75149.1: oxidoreductase [Streptomyces avermitilis MA-4680]
NlpC/P60-like cell-wall peptidase, putative
encoded by transcript AFUA_8G00360A; similar to GB:CAB65565.1: putative membrane protein [Streptomyces coelicolor]
encoded by transcript AFUA_8G00370A; similar to GB:AAR90246.1: polyketide synthase [Botryotinia fuckeliana]
encoded by transcript AFUA_8G00380A; similar to PIR:B83167: hypothetical protein PA3829 [Pseudomonas aeruginosa]
encoded by transcript AFUA_8G00390A; similar to GB:AAS66016.1: methyltransferase B {Aspergillus parasiticus;}
methionine aminopeptidase, type II, putative
encoded by transcript AFUA_8G00410A; similar to GB:CAD71035.1: probable methionyl aminopeptidase {Neurospora crassa;}
C6 finger transcription factor, putative
encoded by transcript AFUA_8G00420A; similar to GB:AAK69383.1: transcription factor ACEII {Hypocrea jecorina;}
encoded by transcript AFUA_8G00440A; similar to GB:BAC52249.1: cyclohexanone monooxygenase [Bradyrhizobium japonicum]
methionine aminopeptidase, type I, putative
encoded by transcript AFUA_8G00460A; similar to methionine aminopeptidase 1 (SP:P53582) [Homo sapiens]
encoded by transcript AFUA_8G00480A; contains a PhyH domain
encoded by transcript AFUA_8G00490A; similar to GB:AAR90242.1: polyketide synthase {Botryotinia fuckeliana;}
encoded by transcript AFUA_8G00500A; similar to acetyl-CoA synthetase AcoE (GI:32265895) [Helicobacter hepaticus]
cytochrome P450 oxidoreductase OrdA-like, putative
encoded by transcript AFUA_8G00510A; similar to O-methylsterigmatocystin oxidoreductase OrdA, AflQ (Swiss-Prot:O13345) [Aspergillus parasiticus] PubMed=9835571, 10855719, 15094053 similar to O-methylsterigmatocystin oxidoreductase (Swiss-Prot:P79084) [Aspergillus flavus] PubMed=9143099
transcript AFUA_8G00540A; non-consensus splice site
encoded by transcript AFUA_8G00540A; non-consensus splice site
encoded by transcript AFUA_8G00550A; similar to methyltransferase GliN (GI:56609351) [Aspergillus fumigatus] PMID: 15979823 similar to ubiE/COQ5 family methyltransferase UmtA that negatively regulates sexual development [Emericella nidulans] similar to methyltransferase SirN (GI:46578134) [Leptosphaeria maculans] PMID: 15387811
cytochrome P450 oxidoreductase, putative
encoded by transcript AFUA_8G00560A; similar to GB:BAC21103.1: cytochrome P450 2 Le.CYP2 [Lentinula edodes] similar to SP:P79084: O-methylsterigmatocystin oxidoreductase [Aspergillus flavus]
encoded by transcript AFUA_8G00570A; similar to GB:AAN70113.1: hydrolase, alpha/beta fold family [Pseudomonas putida KT2440]
encoded by transcript AFUA_8G00580A; similar to GB:AAH07949.2: EEF1G protein [Homo sapiens]
NAD dependent epimerase/dehydratase family protein
encoded by transcript AFUA_8G00610A; similar to GB:AAF74764.1: MAS1 protein [Magnaporthe grisea]
encoded by transcript AFUA_8G00660A; similar to glucose-6-phosphate/phosphate-translocator precursor (GI:2997591) [Pisum sativum]
encoded by transcript AFUA_8G00680A; similar to GB:AAQ60348.1: cellulose synthase, subunit A [Chromobacterium violaceum]
encoded by transcript AFUA_8G00700A; similar to endochitinase CHI2 (GI:9971103) [Metarhizium anisopliae] similar to endochitinase 2; Cts1p (GI:6323316) [Saccharomyces cerevisiae]
secreted antimicrobial peptide, putative
encoded by transcript AFUA_8G00710A; similar to GB:AAL05054.1: antimicrobial peptide AMP3 [Pinus sylvestris] PMID: 14612232, 15108035
encoded by transcript AFUA_8G00720A; similar to SP:P38680: N amino acid transport system protein, Methyltryptophan resistance protein {Neurospora crassa;}
transcription regulator (RTG2), putative
atcacgtgcctgaatgataactaatcgacaaacctgcttatca gtttggtccgtttacattcgccagccacaaagggaaagtggc
encoded by transcript AFUA_8G00790A; potential sequencing error
encoded by transcript AFUA_8G00840A; similar to GABA permease (GI:4972245) [Emericella nidulans]
spherulin 4-like cell surface protein, putative
encoded by transcript AFUA_8G00900A; similar to spherulin 4 precursor(GI:3232) [Physarum polycephalum] PMID: 2930775
UDP-glucose dehydrogenase Ugd1, putative
encoded by transcript AFUA_8G00920A; similar to GB:AAK95561.1: UDP-glucose dehydrogenase Ugd1p [Cryptococcus neoformans var. neoformans] PMID: 15590833
encoded by transcript AFUA_8G00962A; similar to GB:BAB59027.1: cytochrome P450 [Trametes versicolor] PMID: 11831480
encoded by transcript AFUA_8G01000A; contains Ankyrin repeats
thermophilic desulfurizing enzyme family protein
encoded by transcript AFUA_8G01010A; similar to GB:AAT78718.1: DBT monooxygenase [Gordonia alkanivorans] similar to Dibenzothiophene desulfurization enzyme C (DBT sulfur dioxygenase) (Swiss-Prot:P54998) [Rhodococcus sp. IGTS8] PubMed=7961424 PubMed=7574582
encoded by transcript AFUA_8G01020A; similar to heterokaryon incompatibility protein Het-6(OR) (Q9UV10) [Neurospora crassa] contains a HET domain
encoded by transcript AFUA_8G01180A; similar to sugar transporter STL1 (SP:P39932) [Saccharomyces cerevisiae]
enoyl-CoA hydratase/isomerase family protein
encoded by transcript AFUA_8G01222A; similar to arthrofactin synthetase B (GI:66844709) [Aspergillus fumigatus Af293]
ferric-chelate reductase (Fre2), putative
encoded by transcript AFUA_8G01310A; similar to ferric reductase and cupric reductase, reduces siderophore-bound iron and oxidized copper prior to uptake by transporters; expression induced by low iron levels but not by low copper levels; Fre2p (GI:6322629) [Saccharomyces cerevisiae]
encoded by transcript AFUA_8G01370A; similar to GB:CAD01124.1: related to 7alpha-cephem-methoxylase P8 chain {Neurospora crassa;} similar to methyltransferase CmcJ [Streptomyces clavuligerus] PMID: 9696752, 7721717
encoded by transcript AFUA_8G01380A; similar to disease resistance protein (CC-NBS-LRR class) (GI:15222893) [Arabidopsis thaliana] contains a NB-ARC and TPR domains
mitochondrial carrier protein (Pet8), putative
encoded by transcript AFUA_8G01410A; identical to chitinase ChiB1 (GI:28974546) [Aspergillus fumigatus]
oxidoreductase, zinc-binding dehydrogenase family, putative
encoded by transcript AFUA_8G01430A; similar to TOXD portein; unique to isolates that make the cyclic peptide HC-toxin (SP:P54006) [Cochliobolus carbonum] imilar to enoyl reductase (GI:4959947) [Aspergillus terreus]
flavin containing amine oxidase, putative
encoded by transcript AFUA_8G01530A; similar to GB:AAP89014.1: Nsd (GI:32892150) [Myxococcus xanthus] PMID: 15150233
oxidoreductase, short chain dehydrogenase/reductase family superfamily
encoded by transcript AFUA_8G01560A; similar to aldo-keto reductase YakC (GI:1351673) [Schizosaccharomyces pombe]
ADP-ribosylglycohydrolase family protein
aminotransferase, classes I and II family
pyridine nucleotide-disulphide oxidoreductase family protein
encoded by transcript AFUA_8G01630A; similar to NADH dehydrogenase-like protein yjlD (EC 1.6.99.-) (Glucosestarvation-inducible protein 5) (GSI5). (Swiss-Prot:P80861) [Bacillus subtilis;] PubMed=9579062 PubMed=9298659
encoded by transcript AFUA_8G01640A; similar to NcpB [Nostoc sp. ATCC 53789] PMID: 12515465
encoded by transcript AFUA_8G01670A; identical to catalase-peroxidase Cat2p (GI:31074945) [Aspergillus fumigatus] PMID: 12761140
antigenic thaumatin domain protein, putative
encoded by transcript AFUA_8G01710A; similar to thaumatin-like pathogenesis-related protein 1 (GI:1710783) [Avena sativa]
encoded by transcript AFUA_8G01750A; similar to ACOX3 protein (GI:16877606) [Homo sapiens]
encoded by transcript AFUA_8G01800A; similar to SP:P25325: 3-mercaptopyruvate sulfurtransferase (MST) [Homo sapiens]
phosphate-repressible phosphate permease, putative
Na+/H+ exchanger family protein, putative
encoded by transcript AFUA_8G01910A; similar to one of three repressible acid phosphatases, a glycoprotein that is transported to the cell surface by the secretory pathway; induced by phosphate starvation and coordinately regulated by PHO4 and PHO2; Pho11p (GI:6319351)[Saccharomyces cerevisiae]
encoded by transcript AFUA_8G01930A; similar to GB:AAO34671.1: methyltransferase [Gibberella zeae] similar to GB:AAR01218.1: LaeA [Aspergillus fumigatus]
extracellular endo-polygalacturonase, putative
sorbitol/xylitol dehydrogenase, putative
encoded by transcript AFUA_8G02000A; similar to sorbitol dehydrogenase (L-iditol 2-dehydrogenase) (Swiss-Prot:P35497) [Saccharomyces cerevisiae] PubMed = 8125328 similar to xylitol dehydrogenase, converts xylitol to D-xylulose in the endogenous xylose utilization pathway; Xyl2p (GI:6323099) [Saccharomyces cerevisiae]
encoded by transcript AFUA_8G02010A; similar to High-affinity glucose transporter (Swiss-Prot:P49374) [Kluyveromyces lactis] PubMed=8830679 similar to glycerol proton symporter of the plasma membrane, subject to glucose-induced inactivation, strongly but transiently induced when cells are subjected to osmotic shock; Stl1p (GI:6320745) [Saccharomyces cerevisiae] PubMed=8076821
glycan biosynthesis protein (PigL), putative
encoded by transcript AFUA_8G02060A; similar to phosphatidylinositol glycan biosynthesis protein (GI:20302097) [Rattus norvegicus]
1,3-beta-glucanosyltransferase, putative
encoded by transcript AFUA_8G02130A; similar to glycolipid anchored surface protein Gas1 (Swiss-Prot:P22146) [Saccharomyces cerevisiae]
encoded by transcript AFUA_8G02140A; similar to Ankyrin 1; Erythrocyte ankyrin; Ankyrin R (Swiss-Prot:P16157) [Homo sapiens]
acetylornithine aminotransferase, putative
encoded by transcript AFUA_8G02180A; similar to GB:CAB43936.1: GABA permease gabA [Emericella nidulans] PMID: 10320578 similar to GB:CAE47957.1: GabA permease, putative [Aspergillus fumigatus]
encoded by transcript AFUA_8G02200A; SP:P18696: Proline-specific permease (Proline transport protein). {Emericella nidulans;} ^|^GB|CAA56191.1|1030723|ANPRNB1 proline permease {Emericella nidulans}
alpha-ketoglutarate-dependent taurine dioxygenase
dihydrodipicolinate synthetase family protein
encoded by transcript AFUA_8G02270A; similar to Dihydrodipicolinate synthase (GB:CAG85783) [Archaeoglobus fulgidus] similar to N-acetylneuraminate lyase (EC 4.1.3.3) (N-acetylneuraminic acidaldolase) (N-acetylneuraminate pyruvate-lyase) (Sialic acid lyase)(Sialate lyase) (Sialic acid aldolase) (NALase). (Swiss-Prot:P06995) [Escherichia coli;Shigella flexneri;Escherichia coli O157:H7;]
FMN-dependent dehydrogenase family protein
capsule polysaccharide synthase Cps1, putative
encoded by transcript AFUA_8G02320A; similar to polysaccharide synthase Cps1p (GI:37530003) [Filobasidiella neoformans] PMID: 15590825
encoded by transcript AFUA_8G02350A; similar to citrinin polyketide synthase PksCT (GI:52000443) [Monascus purpureus] PMID:14963915
TRI7-like toxin biosynthesis protein, putative
encoded by transcript AFUA_8G02360A; similar to GB:AAK53575.1: TRI7 [Gibberella zeae] PMID: 11976083
encoded by transcript AFUA_8G02380A; similar to FAD-dependent monooxygenase PaxM (GI:13021723) [Penicillium paxilli] similar to Zeaxanthin epoxidase, chloroplast (Swiss-Prot:Q40412) [Nicotiana plumbaginifolia;] PubMed=9808747 similar to Zeaxanthin epoxidase, chloroplast (Swiss-Prot:Q96375) [Capsicum annuum;] PubMed=8910532
geranylgeranyl pyrophosphate synthetase AtmG, putative
encoded by transcript AFUA_8G02400A; similar to geranylgeranyl diphosphate synthase AtmG (GI:49409613) [Aspergillus flavus] PMID: 15528556
encoded by transcript AFUA_8G02410A; similar to geranyl diphosphate: 4-hydroxybenzoate geranyltransferase PGT-1 (GI:18389306) [Lithospermum erythrorhizon] PMID: 11744717
zinc-binding alcohol dehydrogenase, putative
encoded by transcript AFUA_8G02430A; similar to OMNI:GMSORF2317: oxidoreductase, zinc-binding [Mycobacterium smegmatis str.] MC2 155]
encoded by transcript AFUA_8G02440A; similar to GB:AAS56153.1: YGR060W {Saccharomyces cerevisiae;}
encoded by transcript AFUA_8G02510A; contains glycosyl hydrolase domain
encoded by transcript AFUA_8G02530A; similar to Lipase 2 precursor (EC 3.1.1.3) (Lipase II) (GCL II). (Swiss-Prot:P22394) [Galactomyces geotrichum] PubMed=8464065 similar to Lipase 2 precursor (EC 3.1.1.3) (Swiss-Prot:P32946) [Candida rugosa] PubMed=1610906
encoded by transcript AFUA_8G02550A; similar to peptide transporter Ptr2 (SP:Q9P380) [Schizosaccharomyces pombe]
glyceraldehyde-3-phosphate dehydrogenase, putative
encoded by transcript AFUA_8G02570A; similar to OMNI:GMSORF2039: monooxygenase, flavin-binding family [Mycobacterium smegmatis]
short-chain dehydrogenase/reductase 2, putative
encoded by transcript AFUA_8G02610A; similar to GB:AAN74818.1: Fum15p {Gibberella moniliformis;}
encoded by transcript AFUA_8G02620A; similar to CobW (GI:38016769) [Klebsiella pneumoniae]
extracellular exo-polygalacturonase, putative
encoded by transcript AFUA_8G02630A; similar to exopolygalacturonase (GI:28975241) [Aspergillus nidulans]
encoded by transcript AFUA_8G02650A; PubMed:9043118
protein phosphatase type 1 complex subunit Hex2/Reg1, putative
encoded by transcript AFUA_8G02720A; similar to regulatory subunit of type 1 protein phosphatase Glc7p, involved in negative regulation of glucose-repressible genes; Reg1p; Hex2 (GI:6320231) [Saccharomyces cerevisiae]
encoded by transcript AFUA_8G02730A; similar to hypothetical protein; Tma22p (GI:6322474) [Saccharomyces cerevisiae]
encoded by transcript AFUA_8G02750A; identical to CgrA (GI:66844557) [Aspergillus fumigatus] PMID: 11798057, 15271935, 16314125 similar to protein involved in nucleolar integrity and processing of the pre-rRNA for the 60S ribosome subunit; transcript is induced in response to cytotoxic stress but not genotoxic stress; Cgr1p (GI:6321409) [Saccharomyces cerevisiae]
mitochondrial ornithine carrier protein AmcA/Ort1, putative
encoded by transcript AFUA_8G02760A; similar to mitochondrial carrier AmcA (GI:17062083) [Emericella nidulans] PMID: 11555288 similar to ornithine transporter of the mitochondrial inner membrane, exports ornithine from mitochondria as part of arginine biosynthesis; human ortholog is associated with hyperammonaemia-hyperornithinaemia homocitrullinuria (HHH) syndrome; Ort1p; ARG11 (GI:6324704) [Saccharomyces cerevisiae]
encoded by transcript AFUA_8G02770A; similar to cytidine deaminase (GB:AAH54036.1) [Homo sapiens]
vacuolar protein sorting protein, putative
Exocyst complex component Sec10, putative
ditrans,polycis-polyprenyl diphosphate synthase
encoded by transcript AFUA_8G02810A; similar to SP:Q8BHL5: Engulfment and cell motility protein 2 (CED-12 homolog A) {Mus musculus]
cell cycle checkpoint protein Rad17, putative
encoded by transcript AFUA_8G02820A; similar to Checkpoint protein rad17. (Swiss-Prot:P50531) [Schizosaccharomyces pombe;] PubMed=8846774 similar to Checkpoint protein RAD24. (Swiss-Prot:P32641) [Saccharomyces cerevisiae;]
UPD-GlcNAc transporter (Mnn2-2), putative
encoded by transcript AFUA_8G02830A; similar to UDP-N-acetylglucosamine transporter; Golgi UDP-GlcNAc transporter (Swiss-Prot:Q00974) [Kluyveromyces lactis]
encoded by transcript AFUA_8G02840A; similar to dynamin-related GTPase required for mitochondrial fission and the maintenance of mitochondrial morphology, assembles on the cytoplasmic face of mitochondrial tubules at sites at which division will occur; also participates in endocytosis; Dnm1p (GI:6323028) [Saccharomyces cerevisiae]
encoded by transcript AFUA_8G02860A; similar to AMP deaminase, tetrameric enzyme that catalyzes the deamination of AMP to form IMP and ammonia; may be involved in regulation of intracellular adenine nucleotide pools; YML035C; Amd1p (GI:6323606) [Saccharomyces cerevisiae]
encoded by transcript AFUA_8G03880A; similar to GB:AAC49007.1: cytoplasmic alanyl-tRNA synthetase {Saccharomyces cerevisiae;}
peptidyl-prolyl cis-trans isomerase, putative
cell cycle regulatory protein Cks/Suc1, putative
encoded by transcript AFUA_8G03920A; similar to subunit of the Cdc28 protein kinase, required for mitotic proteolysis, may also be involved in the proteolysis of the G1 cyclins; Cks1p (GI:6319611) [Saccharomyces cerevisiae] PubMed=3031478 similar to cyclin-dependent kinases regulatory subunit (P13). (Swiss-Prot:P08463) [Schizosaccharomyces pombe] PubMed=2664468 PMID: 3010051
encoded by transcript AFUA_8G03930A; similar to heat shock protein 70 HscA (GI:2764949) [Emericella nidulans] similar to Heat shock protein SSB2(SP:P40150) [Saccharomyces cerevisiae] PMID: 2664714
cytoplasmic protein required for cell viability, putative
encoded by transcript AFUA_8G03980A; contains a DUF59 domain similar to protein required for cell viability; Yhr122wp (GI:6321914) [Saccharomyces cerevisiae]
transcript AFUA_8G03990A; similar to GTPase component of U5 snRNP involved in mRNA splicing via spliceosome; binds directly to U5 snRNA; proposed to be involved in conformational changes of the spliceosome; similarity to ribosomal translocation factor EF-2; Snu114p (GI:6322675) [Saccharomyces cerevisiae]
encoded by transcript AFUA_8G03990A; similar to GTPase component of U5 snRNP involved in mRNA splicing via spliceosome; binds directly to U5 snRNA; proposed to be involved in conformational changes of the spliceosome; similarity to ribosomal translocation factor EF-2; Snu114p (GI:6322675) [Saccharomyces cerevisiae]
cleavage and polyadenylation specificity factor subunit A, putative
encoded by transcript AFUA_8G04040A; similar to cleavage and polyadenylation specificity factor subunit CPSF-160; Cft1p (GI:6320507) [Saccharomyces cerevisiae] similar to cleavage and polyadenylation specificity factor, 160 kDa subunit; CPSF160 kDa subunit (Swiss-Prot:Q10570) [Homo sapiens]
encoded by transcript AFUA_8G04050A; similar to phosphate-non-repressible acid phosphatase PacG (GI:548509) [Emericella nidulans] PMID: 7916713 7628710 similar to VIB-1 (GI:23238263) [Neurospora crassa] contains a NDT80_PhoG domain
encoded by transcript AFUA_8G04060A; similar to N-acetyl-beta-glucosaminidase (Swiss-Prot:P48823) [Alteromonas sp.]
glucosamine-6-phosphate deaminase, putative
encoded by transcript AFUA_8G04070A; similar to glucosamine-6-phosphate deaminase; GNPI (Q64422) [Mesocricetus auratus]
betaine aldehyde dehydrogenase (BadH), putative
encoded by transcript AFUA_8G04080A; simiar to betaine aldehyde dehydrogenase BADH (GI:118491) [Escherichia coli]
encoded by transcript AFUA_8G04090A; similar to choline oxidase CodA (GI:31979241) [Arthrobacter globiformis] MID: 14678796
N-acetylglucosamine-6-phosphate deacetylase (NagA), putative
encoded by transcript AFUA_8G04100A; similar to N-Acetylglucosamine-6-Phosphate Deacetylase, NagA (GI:38493065) [Bacillus Subtilis] similar to AgaA (GI:8895751) [Escherichia coli]
encoded by transcript AFUA_8G04110A; contains a DUF895 domain
encoded by transcript AFUA_8G04120A; similar to carboxypeptidase S1, CPS1 (P34946) [Penicillium janthinellum] similar to carboxypeptidase Y, CBPY (P00729) [Saccharomyces cerevisiae]
C6 transcription factor (Ctf1B), putative
encoded by transcript AFUA_8G04130A; similar to cutinase transcription factor 1, CTF1-beta (GI:1706177) [Nectria haematococca]
rRNA maturation protein (Nop14), putative
origin recognition complex subunit 3, putative
encoded by transcript AFUA_8G04250A; contains pentatricopeptide repeats
encoded by transcript AFUA_8G04270A; similar to SP:P40340: TAT-binding homolog 7. {Saccharomyces cerevisiae;} -
NADH-ubiquinone oxidoreductase 178 kDa subunit, putative
DNA-directed RNA polymerase III subunit 22.9 kDa, putative
encoded by transcript AFUA_8G04350A; similar to GB:AAH17248.1: POLR3H protein [Homo sapiens]
mRNA cleavage and polyadenylation specificity factor complex subunit (Pta1), putative
encoded by transcript AFUA_8G04420A; similar to subunit of holo-CPF, a multiprotein complex and functional homolog of mammalian CPSF, required for the cleavage and polyadenylation of mRNA and snoRNA 3' ends; involved in pre-tRNA processing; binds to the phosphorylated CTD of RNAPII; Pta1p (GI:6319273) [Saccharomyces cerevisiae]
oligosaccharyl transferase subunit (Stt3), putative
COP9 signalosome subunit 8 (CsnH), putative
encoded by transcript AFUA_8G04440A; similar to HCOP9 (GI:1730284) [Homo sapiens]
encoded by transcript AFUA_8G04460A; Similar to GB:AAL67574.1: cytoplasmic dynein intermediate chain {Emericella nidulans;}
encoded by transcript AFUA_8G04510A; similar to pirin; iron-binding nuclear protein (GI:4505823) [Homo sapiens]
cytoskeleton assembly control protein Sla1, putative
misfolded glycoproteins degradation protein Yos9, putative
encoded by transcript AFUA_8G04530A; similar to lectin; soluble lumenal ER protein; member of the OS-9 protein family; similar to mannose-6-phosphate receptors (MPRs); serves as a receptor that recognizes misfolded N-glycosylated proteins and participates in their targeting to ERAD; Yos9p (GI:6320262) [Saccharomyces cerevisiae] PMID: 16168372
encoded by transcript AFUA_8G04550A; contains a ComA domain similar to SP:Q57703: phosphosulfolactate synthase, (2R)-phospho-3-sulfolactate synthase, PSL synthase [Methanocaldococcus jannaschii]
encoded by transcript AFUA_8G04590A; similar to PIR:T50168: probable U4/U6 small nuclear ribonucleoprotein [imported] fission yeast (Schizosaccharomyces pombe)
encoded by transcript AFUA_8G04610A; contains a DnaJ domain
C4-dicarboxylate transporter/malic acid transport protein, putative
3-hydroxyanthranilate 3,4-dioxygenase Bna1, putative
encoded by transcript AFUA_8G04650A; similar to 3-hydroxyanthranilic acid dioxygenase, required for biosynthesis of nicotinic acid from tryptophan via kynurenine pathway; Bna1p (GI:6322485) [Saccharomyces cerevisiae]
serine/threonine protein kinase, putative
oxidoreductase, short-chain dehydrogenase/reductase family, putative
encoded by transcript AFUA_8G04710A; similar to GB:BAC75546.1: xylosidase [Penicillium herquei] PMID: 16233536
encoded by transcript AFUA_8G04740A; Similar to SP:P32639: Pre-mRNA splicing helicase BRR2 (EC 3.6.1.-) (Protein Snu246). {Saccharomyces cerevisiae;}
DNA mismatch repair protein Msh1, putative
encoded by transcript AFUA_8G04760A; similar to SP:P32459: Ureidoglycolate hydrolase [Saccharomyces cerevisiae]
peroxisomal membrane protein (PmpP24), putative
encoded by transcript AFUA_8G04780A; similar to GB:CAB71345.1: PMP24 protein [Mus musculus]
encoded by transcript AFUA_8G04790A; similar to SP:P36160: Ribosome biogenesis protein RPF2. {Saccharomyces cerevisiae;}
encoded by transcript AFUA_8G04810A; similar to Casein kinase II, alpha chain (EC 2.7.1.37) (CK II alpha subunit). (Swiss-Prot:Q8TG13) [Neurospora crassa;]
ribonuclease P complex subunit Pop2, putative
encoded by transcript AFUA_8G04820A; similar to subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends; Rpp1p (GI:6321853) [Saccharomyces cerevisiae] PMID: 9353260 similar to ribonuclease P protein subunit p30 (EC 3.1.26.5) (RNaseP protein p30)(RNase P subunit 2). (Swiss-Prot:P78346) [Homo sapiens;] PubMed=9037013
NAD binding Rossmann fold oxidoreductase, putative
COP9 signalosome subunit 1 (CsnA), putative
encoded by transcript AFUA_8G04880A; similar to COP9 signalosome complex subunit 1 (Swiss-Prot:P45432) [Arabidopsis thaliana] contains a PCI domain
encoded by transcript AFUA_8G04910A; similar to choline transporter (permease) that also controls the uptake of nitrogen mustard; expression is co-regulated with phospholipid biosynthetic genes and negatively regulated by choline and myo-inositol; Hnm1p (GI:6321361) [Saccharomyces cerevisiae]
sn-1,2-diacylglycerol cholinephosphotransferase
transcription initiation factor TFIID subunit TSM1/127kD, putative
encoded by transcript AFUA_8G04950A; similar to GB:CAB08750.2: transcription initiation factor TFIID subunit TSM1 {Schizosaccharomyces pombe;}
small nuclear ribonucleoprotein SmG, putative
bis(5'-nucleosyl)-tetraphosphatase, putative
encoded by transcript AFUA_8G05000A; similar to diadenosine 5',5''-P1,P4-tetraphosphate phosphorylase I (AP4A phosphorylase), involved in catabolism of bis(5'-nucleosidyl) tetraphosphates; has similarity to Apa2p; Apa1p (GI:10383757) [Saccharomyces cerevisiae]
beta-N-acetylhexosaminidase NagA, putative
encoded by transcript AFUA_8G05020A; similar to beta-N-acetylglucosaminidase (GI:25900981) [Aspergillus oryzae] similar to beta-hexosaminidase HEX1 (GI:1170249) [Candida albicans]
encoded by transcript AFUA_8G05090A; similar to protein of unknown function containing 8 putative transmembrane seqments; ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression; Bsc6p (GI:6324435) [Saccharomyces cerevisiae]
peroxisomal membrane protein (Pex13), putative
encoded by transcript AFUA_8G05170A; similar to autophagy protein APG6 (SP:Q02948) [Saccharomyces cerevisiae]
peroxisomal targeting signal-1 receptor (PEX5), putaitve
encoded by transcript AFUA_8G05240A; similar to peroxisomal targeting signal receptor; PAY32/Peroxin-5 (GI:2501342) [Yarrowia lipolytica] similar to protein essential for import of proteins into peroxisomal matrix; Pex5p (GI:6320450) [Saccharomyces cerevisiae] contains TPR domains
RNA interference and gene silencing protein (Qde2), putative
encoded by transcript AFUA_8G05280A; similar to GB:AAL06079.1: QDE2 protein {Blumeria graminis;}
encoded by transcript AFUA_8G05310A; contains a DUF962 domain
mitochondrial F1 ATPase subunit alpha, putative
encoded by transcript AFUA_8G05320A; similar to ATP synthase alpha chain, mitochondrial precursor (Swiss-Prot:P07251) [Saccharomyces cerevisiae]
signal peptidase complex component, putative
DNA repair/transcription protein, putative
ribosome biogenesis protein Noc4, putative
encoded by transcript AFUA_8G05430A; similar to nucleolar protein, forms a complex with Nop14p that mediates maturation and nuclear export of 40S ribosomal subunits; Noc4p (GI:6325402) [Saccharomyces cerevisiae]
mitochondrial ATPase subunit ATP4, putative
encoded by transcript AFUA_8G05440A; similar to ATP synthase subunit 4, mitochondrial (Swiss-Prot:P05626) [Saccharomyces cerevisiae] PMID: 9660917
encoded by transcript AFUA_8G05460A; similar to MEDIAN BODY PROTEIN (GI:1170907) [Giardia intestinalis]
transcription initiation factor iif, beta subunit
encoded by transcript AFUA_8G05500A; similar to COP9 signalosome subunit 4 (GI:21553897) [Emericella nidulans] PMID: 12864854
encoded by transcript AFUA_8G05530A; similar to fumarate reductase, catalyzes the reduction of fumarate to succinate, required for the reoxidation of intracellular NADH under anaerobic conditions; mutations cause osmotic sensitivity; Osm1p (GI:6322511) [Saccharomyces cerevisiae]
protein phosphatase PP2A regulatory B subunit, putative
encoded by transcript AFUA_8G05560A; similar to GB:AAD15987.1: protein phosphatase 2A regulatory B subunit [Neurospora crassa]
encoded by transcript AFUA_8G05580A; similar to acetyl-coA hydrolase, primarily localized to mitochondria; required for acetate utilization and for diploid pseudohyphal growth; Ach1p (GI:6319456) [Saccharomyces cerevisiae] PMID: 12606555
oxidoreductase, short chain dehydrogenase/reductase family
encoded by transcript AFUA_8G05610A; similar to Soluble Cell Wall protein; Scw11p (GI:6321410) [Saccharomyces cerevisiae] similar to family 17 glucosidase SCW10 (Swiss-Prot:Q04951) [Saccharomyces cerevisiae]
chitin synthase activator (Chs3), putative
encoded by transcript AFUA_8G05620A; similar to Activator of Chs3p (chitin synthase III), SKT5 (GI:6319410) [Saccharomyces cerevisiae]
encoded by transcript AFUA_8G05640A; contains WD repeats
encoded by transcript AFUA_8G05660A; similar to one of two type I myosins; contains proline-rich tail homology 2 (TH2) and SH3 domains; MYO5 deletion has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization; Myo5p (GI:6323756) [Saccharomyces cerevisiae]
encoded by transcript AFUA_8G05670A; contains an OPA3 domain
encoded by transcript AFUA_8G05680A; similar to serine/threonine protein kinase plo1 (Swiss-Prot:P50528) [Schizosaccharomyces pombe]
encoded by transcript AFUA_8G05710A; similar to glycerol proton symporter of the plasma membrane, subject to glucose-induced inactivation, strongly but transiently induced when cells are subjected to osmotic shock; Stl1p (GI:6320745) [Saccharomyces cerevisiae] PubMed=8076821
encoded by transcript AFUA_8G05720A; contains a DUF567 domain
encoded by transcript AFUA_8G05740A; similar to SP:P40113: RTM1 protein. {Saccharomyces cerevisiae;}
encoded by transcript AFUA_8G05780A; similar to vegetatible incompatibility protein HET-E-1 (GI:3023956) [Podospora anserina] PMID: 9435787, 12019224, 10782090, 7920254 contains NACHT and Ankyrin domains
encoded by transcript AFUA_8G05810A; contains a DUF1295 domain
encoded by transcript AFUA_8G05820A; similar to PMS1 postmeiotic segregation increased 1 (GI:29725938) [Homo sapiens]
palmitoyltransferase with autoacylation activity Pfa4, putative
encoded by transcript AFUA_8G05830A; similar to palmitoyltransferase with autoacylation activity; member of a family of putative palmitoyltransferases containing an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain; Pfa4p (GI:6324571) [Saccharomyces cerevisiae]
fungal specific transcription factor, putative
FAD dependent oxidoreductase superfamily
aromatic amino acid and leucine permease
2-haloalkanoic acid dehalogenase, putative
encoded by transcript AFUA_8G05880A; similar to 10 kDa chaperonin; Protein Cpn10; groES protein (GI:231748) [Streptomyces albus G] PMID: 1682304
toxin biosynthesis protein (Tri7), putative
phosphotransferase enzyme family protein
encoded by transcript AFUA_8G06030A; similar to mutanase MutA (GI:6752866) [Penicillium purpurogenum] similar to mutanase (GI:15072711) [Emericella nidulans]
encoded by transcript AFUA_8G06080A; similar to nitric oxide oxidoreductase, flavohemoglobin involved in nitric oxide detoxification; plays a role in the oxidative and nitrosative stress responses; Yhb1p [Saccharomyces cerevisiae]
encoded by transcript AFUA_8G06090A; similar to GB:CAB43936.1: GABA permease {Emericella nidulans;}
encoded by transcript AFUA_8G06132A; similar to extracellular developmental signal biosynthesis protein Flug (GI:450258) [Emericella nidulans] PUBMED 7926755 identical to RF:XP_747414.1: developmental control protein FluG [Aspergillus fumigatus Af293]
sensor histidine kinase/response regulator, putative
encoded by transcript AFUA_8G06140A; simiar to GB:AAQ19475.1: histidine kinase G7 {Emericella nidulans;}
encoded by transcript AFUA_8G06180A; similar to doc (GI:1359621) [Escherichia coli]
ttctctatttccttagcttccttaggttttgcattgcttttgt acgcattttgcatcgcctttgcatgaatttgtataga
metalloreductase transmembrane component, putative
ctggtgtacctcccagtgtccctggtggcatgactgttggagc tacacctt
encoded by transcript AFUA_8G06280A; similar to GB:AAS46019.1: casein kinase I alpha isoform {Toxoplasma gondii;}
encoded by transcript AFUA_8G06350A; similar to GB:AAD34550.1: esterase {Aspergillus terreus;}
encoded by transcript AFUA_8G06360A; similar to mutanase MutA (GI:6752866) [Penicillium purpurogenum] similar to mutanase (GI:15072711) [Emericella nidulans]
encoded by transcript AFUA_8G06370A; similar to GB:AAO34404.1: zeaxanthin epoxidase precursor [Chlamydomonas reinhardtii]
encoded by transcript AFUA_8G06380A; contains Ankyrin repeats
encoded by transcript AFUA_8G06400A; similar to Het-eN (GI:46102475) [Nectria haematococca] contains Pfs, NACHT, and Ankyrin domains
gactccaaggacaaagatgggcggacaccactgtcatgggcag caggacagggaaataagacaatagtcaagctatcaccaccaacaggccaagttgatcc a
gactccaaggacaaagatgggcggacaccgctgtcatgggcag cagcaaagggaaatgagacaatagtcaaactattactagcaacaaaccaagttgatcc a
encoded by transcript AFUA_8G06405A; similar to CipA protein (GI:20429038) [Emericella nidulans] PMID: 12207217
encoded by transcript AFUA_8G06410A; GB:AAD25538.1: tetracycline resistance protein [Pseudomonas sp.]
ttcttctacaccaattacgaccttgaaaagcgtgacgaagagc tcgacaagcgg
encoded by transcript AFUA_8G06440A; similar to GB:CAA70218.1: fructosyl amino acid oxidase {Aspergillus terreus;}
encoded by transcript AFUA_8G06450A; similar to OMNI:GMSORF0282: Rieske 2Fe-2S family protein, putative {Mycobacterium smegmatis str. MC2 155;}
encoded by transcript AFUA_8G06460A; similar to SP:P28349: Nitrogen assimilation transcription factor nit-4 [Neurospora crassa]
encoded by transcript AFUA_8G06470A; similar to N,N-dimethylglycine oxidase dmg (GI:13241956) [Arthrobacter globiformis] PMID: 11422368 similar to dimethylglycine dehydrogenase, mitochondrial precursor (ME2GLYDH) (Swiss-Prot:Q9UI17) [Homo sapiens] PubMed=10102904
rhamnogalacturonan acetylesterase superfamily protein
encoded by transcript AFUA_8G06480A; similar to GB:AAO79278.1: putative rhamnogalacturonan acetylesterase [Bacteroides thetaiotaomicron VPI-5482]
peptidyl-arginine deiminase domain protein
encoded by transcript AFUA_8G06520A; similar to GB:AAT02835.1: peptidyl-arginine deiminase-like protein [Listeria monocytogenes str. 4b F2365]
encoded by transcript AFUA_8G06530A; similar to SP:Q8R090: chromaffin granule amine transporter, Vesicular amine transporter 1, VAT1 [Mus musculus]
encoded by transcript AFUA_8G06554A; similar to carbonic anhydrase; poorly transcribed under aerobic conditions and at an undetectable level under anaerobic conditions; involved in non-classical protein export pathway; Nce103p (GI:6324292) [Saccharomyces cerevisiae]
encoded by transcript AFUA_8G06560A; contains a DUF895 domain
encoded by transcript AFUA_8G06580A; similar to GB:CAB43936.1: GABA permease GabA [Emericella nidulans] PMID: 10320578
encoded by transcript AFUA_8G06600A; similar to protein of unknown function, transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance; Yll056cp (GI:6322972) [Saccharomyces cerevisiae]
intermediate filament associated protein, putative
encoded by transcript AFUA_8G06630A; similar to Plectin 1 (PLTN) (PCN) (300-kDa intermediate filament associated protein) (IFAP300) [Cricetulus griseus]
encoded by transcript AFUA_8G06640A; similar to menaquinone biosynthesis methyltransferase ubiE Swiss-Prot:O86169) [Geobacillus stearothermophilus] PubMed=9139683
short-chain dehydrogenase/reductase family protein, putative
encoded by transcript AFUA_8G06680A; similar to peroxisomal acyl-CoA thioesterase likely to be involved in fatty acid oxidation rather than fatty acid synthesis; conserved protein also found in human peroxisomes; TES1 mRNA levels increase during growth on fatty acids; Tes1p (GI:6322480) [Saccharomyces cerevisiae]
encoded by transcript AFUA_8G06700A; identical to annexin ANXC3.1 (GI:47059731) [Aspergillus fumigatus] PMID: 15044005
UDP-glucose,sterol transferase, putative
encoded by transcript AFUA_8G06760A; similar to GB:AAL68895.1: aminotriazole resistance protein [Exophiala dermatitidis]
encoded by transcript AFUA_8G06840A; similar to NADPH-dependent 1-acyl dihydroxyacetone phosphate reductase found in lipid particles, ER, and mitochondrial outer membrane; involved in phosphatidic acid biosynthesis; required for spore germination; capable of metabolizing steroid hormones; Ayr1p (GI:6322067) [Saccharomyces cerevisiae]
encoded by transcript AFUA_8G06890A; similar to endo-xylogalacturonan hydrolase (GI:6686870) [Aspergillus tubingensis]
encoded by transcript AFUA_8G06920A; similar to SP:P40309: K(+)/H(+) antiporter Kha1 [Saccharomyces cerevisiae]
encoded by transcript AFUA_8G07060A; similar to hydrophobin (GI:577666) HYP1 [Aspergillus fumigatus] PUBMED 12620846, 7927700
encoded by transcript AFUA_8G07070A; similar to GB:BAB59003.1: maltase [Aspergillus oryzae]
encoded by transcript AFUA_8G07080A; identical to metalloprotease; MEP (SP:P46074) [Aspergillus fumigatus] PMID: 7927676 PMID: 8188335 PMID: 7558282 PMID: 7715453
extracellular proline-serine rich protein
encoded by transcript AFUA_8G07120A; similar to beta-1,6-glucanase Neg1 (GI:20373090) [Neurospora crassa] PMID: 12162562
AhpC/TSA family thioredoxin peroxidase, putative
encoded by transcript AFUA_8G07130A; similar to GB:CAG77959.1: unnamed protein product; similar to sp|P34227 Saccharomyces cerevisiae YBL064c, hypothetical start {Yarrowia lipolytica CLIB99;}
arsenic resistance protein ArsH, putative
encoded by transcript AFUA_8G07150A; similar to arsH (GI:32470162) [Salmonella typhimurium] contains an FMN_red domain
hydroxymethylglutaryl-CoA synthase, putative
encoded by transcript AFUA_8G07210A; similar to Hydroxymethylglutaryl-CoA synthase (EC 2.3.3.10) (HMG-CoA synthase)(3-hydroxy-3-methylglutaryl coenzyme A synthase). (Swiss-Prot:P54839) [Saccharomyces cerevisiae] similar to Hydroxymethylglutaryl-CoA synthase (EC 2.3.3.10) (HMG-CoA synthase)(3-hydroxy-3-methylglutaryl coenzyme A synthase). (Swiss-Prot:P54874) [Schizosaccharomyces pombe] PMID: 8750242
encoded by transcript AFUA_8G07240A; similar to GB:BAB59002.1: maltose permease {Aspergillus oryzae;}
exopolygalacturonase, pseudogene; exopolygalacturonase PGX1 (GI:15029348) [Fusarium oxysporum] possible frameshift
nucleoside-diphosphate-sugar epimerase, putative
isoflavone reductase family protein (CipA), putative
encoded by transcript AFUA_8G07330A; similar to GB:CAC87270.1: CipA protein [Emericella nidulans] PMID: 12207217
encoded by transcript AFUA_8G07340A; similar to GB:CAD21086.1: related to tol protein {Neurospora crassa;}
encoded by transcript AFUA_8G07350A; similar to PDB:1JUH_A: Chain A, Crystal Structure Of Quercetin 2,3-Dioxygenase [Aspergillus japonicus] PMID: 12071961 similar to SP:P42106: Hypothetical protein yxaG. {Bacillus subtilis;}
encoded by transcript AFUA_8G07360A; similar to transcriptional activator Mut3p (GI:21913144) [Pichia angusta]
encoded by transcript AFUA_8G07370A; similar to GB:AAB47713.1: HOL1 {Saccharomyces cerevisiae;}
encoded by transcript AFUA_8G07380A; similar to GB:AAR90252.1: polyketide synthase [Botryotinia fuckeliana]
telomere-associated RecQ helicase, putative