Scheffersomyces stipitis CBS 6054 chromosome 6, complete sequence.
Scheffersomyces stipitis CBS 6054 (Pichia stipitis CBS 6054)
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
Genome sequence of the lignocellulose-bioconverting and xylose-fermenting yeast Pichia stipitis
Submitted (05-JUN-2017) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (12-DEC-2006) US DOE Joint Genome Institute, 2800 Mitchell Drive B100, Walnut Creek, CA 94598-1698, USA
PROVISIONAL REFSEQ: This record has not yet been subject to final\nNCBI review. The reference sequence is identical to CP000500.\nURL -- http://www.jgi.doe.gov/pichia\nJGI Project ID: 3634480\nSource DNA was provided by Jose Laplaza and Thomas Jeffries\n(twjeffri@wisc.edu)\nStock culture is available from Cletus P Kurtzman\n(kurtsman@ncaur.usda.gov)\nContacts: Thomas Jeffries (twjeffri@wisc.edu)\n Paul Richardson (microbes@cuba.jgi-psf.org)\nAnnotation done by JGI-PGF\nManual curation done by the P. stipitis User Community\nFinishing done by JGI-Stanford Human Genome Center\n(www-shgc.stanford.edu)\nThe finished chromosome has no gaps. The sequence has less than one\nerror in 100,000 bp.\nThe JGI and collaborators endorse the principles for the\ndistribution and use of large scale sequencing data adopted by the\nlarger genome sequencing community and urge users of this data to\nfollow them. It is our intention to publish the work of this\nproject in a timely fashion and we welcome collaborative\ninteraction on the project and analysis.\n(http://www.genome.gov/page.cfm?pageID=10506376).\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: INSDC submitter\nAnnotation Status :: Full annotation\nAnnotation Pipeline :: Eukaryotic Annotation Propagation Pipeline\n##Genome-Annotation-Data-END##\nCOMPLETENESS: full length.
go_component membrane; go_function transporter activity; go_process transport
go_component nucleus; go_function transcription factor activity; zinc ion binding; DNA binding; go_process regulation of transcription, DNA-dependent; transcription
related to MDR family transporters (MDR15)
N-acetyl-glucosamine-6-phosphate deacetylase
Glucosamine-6-phosphate isomerase (Glucosamine-6-phosphate deaminase) (GNPDA) (GlcN6P deaminase)
hexokinase I (HXK1); go_function hexokinase activity; ATP binding; go_process glycolysis
putative stress-related vesicular transport protein
Electron transfer flavoprotein alpha-subunit
electron transfer flavoprotein alpha-subunit, mitochondrial precursor (Alpha-ETF) (Yong-Su Jin[2006-01-06 11:32:10]); go_function electron transporter activity; go_process electron transport
Fungal specific transcription factor; possible sucrose or maltose fermentation regulatory protein (MAL33); go_function DNA binding
Glucosidase II catalytic (alpha) subunit and related enzymes, glycosyl hydrolase family 31 Carbohydrate transport and metabolism; go_function hydrolase activity, acting on glycosyl bonds; hydrolase activity, hydrolyzing O-glycosyl compounds; alpha-glucosidase activity
go_component integral to membrane; go_function transporter activity; go_process transport
maltose permease slight similarity to Candida intermedia GXS1; go_component integral to membrane; go_function transporter activity; go_process transport
alpha-glucosidase maltase (MAL2) [EC:3.2.1.20] [KO:K01187]; go_function alpha-amylase activity; go_process carbohydrate metabolism
Fungal transcriptional regulatory protein
Fungal transcriptional regulatory protein (MAL33) (MAL63); go_component nucleus; go_function transcription factor activity; zinc ion binding; DNA binding; go_process regulation of transcription, DNA-dependent; transcription
histone acetyltransferase type B subunit 2
Secretory pathway GDP dissociation inhibitor
Regulates vesicle traffic in secretory pathway by regulating dissociation of GDP from Sec4/Ypt/rab family of GTP-binding proteins; go_process regulation of GTPase activity
go_function metalloexopeptidase activity; peptidase activity; go_process proteolysis and peptidolysis
cysteine-type endopeptidase activity; go_function cysteine-type endopeptidase activity; ubiquitin thiolesterase activity; go_process ubiquitin-dependent protein catabolism
aries arylalkylamine N-acetyltransferase
aries arylalkylamine N-acetyltransferase (SNAT); go_function N-acetyltransferase activity
go_component nucleus; small nucleolar ribonucleoprotein complex
go_function two-component response regulator activity; DNA binding; go_process two-component signal transduction system (phosphorelay); regulation of transcription, DNA-dependent
go_component membrane; go_function ATP binding; go_process transport
go_function transaminase activity; go_process biosynthesis
go_function cysteine-type endopeptidase activity; ubiquitin thiolesterase activity; go_process ubiquitin-dependent protein catabolism
go_function nucleic acid binding; helicase activity; ATP binding
go_function protein kinase activity; ATP binding; go_process protein amino acid phosphorylation
mitochondrial elongation factor G- like protein
go_function GTP binding; translation elongation factor activity; go_process protein biosynthesis; translational elongation
transcription activator involved in proline utilization potential fungal Zn(2)-Cys(6) binuclear cluster domain
go_function electron transporter activity; go_process electron transport
Pleiotropic drug resistance proteins (PDR1-15), ABC superfamily; go_component membrane; go_function ATP binding; go_process transport
the plant PR-1 class of pathogen related protein-like protein
DRAP deaminase and pseudouridylate synthase
Has EST support; involved in riboflavin synthesis
involved in riboflavin synthesis; go_function RNA binding; pseudouridine synthase activity; go_process RNA processing; go_function RNA binding; pseudouridine synthase activity; go_process RNA processing
member of Set1p complex, histone methyl transferase
go_function alanine racemase activity; pyridoxal phosphate binding
DNA polymerase alpha-primase complex B subunit
DNA polymerase alpha-primase complex B subunit Required for DNA synthesis and correct progression through S phase plays an essential role at early stage of chromosomal DNA replication, before the hydroxyurea-sensitive step; go_component nucleus; go_process DNA replication
go_function hydrolase activity; go_process metabolism
go_function legumain activity; cysteine-type endopeptidase activity; go_process proteolysis and peptidolysis
go_component nucleus; go_function transcription factor activity; go_process regulation of transcription, DNA-dependent
GATA-family of DNA binding protein-like protein
go_component nucleus; go_function transcription factor activity; go_process regulation of transcription, DNA-dependent; go_component nucleus; go_function transcription factor activity; go_process regulation of transcription, DNA-dependent
Peroxisomal biogenesis factor 3 (Peroxin-3)
Peroxisomal biogenesis factor 3 (Peroxin-3) (Peroxisomal membrane protein PAS2); go_component integral to peroxisomal membrane; go_process peroxisome organization and biogenesis
mitochondrial 54S ribosomal protein YmL3
go_function RNA binding; ribonuclease III activity; go_process RNA processing
go_function catalytic activity; phosphoribosylamine-glycine ligase activity; go_process purine base biosynthesis
go_function glutamate-cysteine ligase activity; go_process glutathione biosynthesis
Protein involved in (1,3)-beta-glucan synthesis
Has EST support; possibly involved through regulation of cell wall glucan and chitin synthesis chromatin binding protein
possibly involved through regulation of cell wall glucan and chitin synthesis chromatin binding protein
Nicotinate-nucleotide pyrophosphorylase [carboxylating] (Quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase)
Biosynthesis of Nicotinic Acid Nicotinate-nucleotide pyrophosphorylase [carboxylating] (Quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase); go_function nicotinate-nucleotide diphosphorylase (carboxylating) activity; go_process NAD biosynthesis
N-acetyltransferase ECO1 (Establishment of cohesion protein 1)
Protein involved in establishing cohesion between sister chromatids during DNA replication
Mitochondrial tricarboxylate/dicarboxylate carrier protein
Mitochondrial tricarboxylate/dicarboxylate carrier proteins; go_component membrane; go_function binding; go_process transport
go_component nucleus; go_function transcription factor activity; zinc ion binding; go_process regulation of transcription, DNA-dependent
CCAAT-binding factor, subunit B (HAP2); go_component nucleus; go_function transcription factor activity; go_process regulation of transcription, DNA-dependent
CAS specific exportin for Srp1p required for accurate mitotic chromosome segregation
Importin alpha re-exporter (Chromosome segregation protein CSE1) (Cellular apoptosis susceptibility protein homolog) with sequence similarity to CAS specific exportin for Srp1p required for accurate mitotic chromosome segregation; go_function importin-alpha export receptor activity; protein transporter activity; go_component nucleus; cytoplasm; nuclear pore; go_process apoptosis; cell proliferation; protein-nucleus import, docking
GDP-mannose transporter into the lumen of the Golgi
GDP-mannose transporter into the lumen of the Golgi May regulate Golgi function and glycosylation in Golgi
go_process nucleoside metabolism; metabolism
ATP-dependent RNA helicase of DEAD box family; go_function nucleic acid binding; helicase activity; ATP binding
Translation elongation factor 2/ribosome biogenesis protein RIA1 and related proteins
go_component intracellular; go_function exonuclease activity
go_component membrane; go_process transport
heme binding fungal transcriptional regulator HBR1; go_function heme binding; transcription factor activity
carbohydrate metabolism, cell wall maintenance
Cinnamyl-alcohol dehydrogenase Flavonol reductase/cinnamoyl-CoA reductase
Cinnamyl-alcohol dehydrogenase Flavonol reductase/cinnamoyl-CoA reductase GRE2-related protein
Suppressor of Sulfoxyde Ethionine resistance
Chorismate mutase; go_function chorismate mutase activity; go_process aromatic amino acid family biosynthesis
copper chaperone involved in lysine biosynthesis and oxidative stress protection
go_function metal ion binding; go_process metal ion transport
Carrier protein, mitochondrial precursor; go_component membrane; go_function binding; go_process transport
with sequence similarity to S. cerevisiae MEP genes
go_function phospholipase activity; go_process phospholipid catabolism
Elongation factor 3A (EF-3A) (EF-3) (Translation elongation factor 3A) (Eukaryotic elongation factor 3) (eEF3) (Yeast elongation factor 3); go_component membrane; go_function ATP binding; go_process transport
Has EST support; involved in the maturation of 25S ribosomal RNA
involved in the maturation of 25S ribosomal RNA; go_function nucleic acid binding; helicase activity; ATP binding; go_function nucleic acid binding; helicase activity; ATP binding
tRNA pseudouridine synthase 3 (tRNA-uridine isomerase 3) (tRNA pseudouridylate synthase 3) (Depressed growth-rate protein DEG1); go_function pseudouridylate synthase activity; go_process tRNA processing
Putative arsenical pump-driving ATPase (Arsenite-translocating ATPase) (Arsenical resistance ATPase) (Arsenite-transporting ATPase); go_component membrane; go_function ATP binding; go_process anion transport
Eukaryotic translation initiation factor 3 39 kDa subunit (eIF3 p39) (Translation initiation factor eIF3, p39 subunit)
go_function DNA binding; ATP binding; nucleic acid binding; helicase activity
L-aminoadipate-semialdehyde dehydrogenase, large subunit
L-aminoadipate-semialdehyde dehydrogenase large subunit (Alpha-aminoadipate reductase) (Alpha-AR); go_function catalytic activity; cofactor binding; go_process metabolism
go_function 3',5'-cyclic-nucleotide phosphodiesterase activity; go_process signal transduction
Ras-related GTPase; go_function GTP binding; go_process small GTPase mediated signal transduction
Tuftelin-interacting protein TIP39, contains G-patch domain
low similarity to Tuftelin-interacting protein 11 in humans similar toprotein required for cell viability in S. cerevisiae; go_component intracellular; go_function nucleic acid binding
accessory factor associated with RNA polymerase II
go_function tRNA ligase activity; ATP binding; go_process tRNA aminoacylation for protein translation; protein biosynthesis
Mitochondrial distribution and morphology protein 31, mitochondrial precursor
Hypothetical membrane protein similar to Mitochondrial distribution and morphology protein 31, mitochondrial precursor
cysteine desulfurase Selenocysteine lyase
Glucan 1,3-beta-glucosidase precursor (Exo-1,3-beta-glucanase)
go_function hydrolase activity, hydrolyzing O-glycosyl compounds; go_process carbohydrate metabolism
Putative ion transporter similar to the major facilitator superfamily of transporters
60S acidic ribosomal protein P1-A (CaRP1A); go_component intracellular; ribosome; go_function structural constituent of ribosome; go_process translational elongation
go_component intracellular; ribosome; go_function structural constituent of ribosome; go_process protein biosynthesis
WD40 repeat protein part of complex that catalyses guanyl nucleotide exchange on Ypt6p
NADH-ubiquinone oxidoreductase B14 subunit (Complex I-B14) (CI-B14)
NADH-ubiquinone oxidoreductase B14 subunit (NB4M) (Complex I-B14) (CI-B14); go_function oxidoreductase activity, acting on NADH or NADPH; go_component mitochondrial inner membrane; go_process electron transport
Tubulin beta chain (Beta tubulin) involved in chromosome segregation and nuclear migration; go_component tubulin; go_function GTPase activity; GTP binding; go_process microtubule polymerization
zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type; go_component nucleus; go_function transcription factor activity; zinc ion binding; go_process regulation of transcription, DNA-dependent
Vacuolar sorting protein SNF7 (Vacuolar protein sorting-associated protein VPS32)
Vacuolar sorting protein SNF7 (Vacuolar protein sorting-associated protein VPS32) Involved in derepression of SUC2 in response to glucose limitation involved in late endosome to vacuole transport; go_function molecular function unknown
mitochondrial DNA-directed RNA polymerase
go_function DNA binding; DNA-directed RNA polymerase activity; go_process transcription
protein kinase activator involved in cell cycle and shape regulation
Maintenance of ploidy protein MOB2 (MPS1 binder 2) Cell cycle-associated protein
go_function phosphatidylserine decarboxylase activity; go_process phospholipid biosynthesis
Anaphase-promoting complex (APC), subunit 1 (meiotic check point regulator/Tsg24)
mitochondrial translation elongation factor TU
go_function GTP binding; go_process protein biosynthesis
low similarity to MUC1, part of complex that catalyses guanyl nucleotide exchange on Ypt6p
Gamma-glutamyltransferase precursor (Gamma-glutamyltranspeptidase) (Gamma-GT) (Extracellular matrix protein 38) (CIK1 suppressor protein 2) [Contains: Gamma-glutamyltransferase heavy chain Gamma-glutamyltransferase light chain]; go_function gamma-glutamyltransferase activity
mitochondrial carnitine acetyltransferase
polarity establishment and bud formation protein
Morphogenesis-related protein MSB1 (Multicopy suppressor of bud emergence 1) polarity establishment and bud formation protein
go_component nucleus; go_function DNA binding; go_process regulation of transcription, DNA-dependent
bZIP protein that binds to CRE motifs, interacts with Mig1p
mannosyl- oligosaccharide 1,2-alpha-mannosidase
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (ER alpha-1,2-mannosidase) (Man(9)-alpha-mannosidase); go_component membrane; go_function mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; calcium ion binding; go_process N-linked glycosylation
heme binding fungal transcrption factor; go_component nucleus; go_function transcription factor activity; zinc ion binding; go_process regulation of transcription, DNA-dependent
3-hydroxy-3-methyl-glutaryl coenzyme A reductase (HMG-CoA)
go_function hydroxymethylglutaryl-CoA reductase (NADPH) activity; go_process biosynthesis
Anthranilate phosphoribosyltransferase (tentative)
go_function GTP binding; go_process small GTPase mediated signal transduction
GTP-binding protein of the ras superfamily
protein putatively involved in cell wall biogenesis and architecture
vacuolar protein sorting-associated protein hydrophilic protein
has cysteine rich putative zinc finger esential for function
has cysteine rich putative zinc finger esential for function; go_function zinc ion binding; go_process intracellular protein transport; go_function zinc ion binding; go_process intracellular protein transport
go_component membrane; go_function drug transporter activity; antiporter activity; go_process multidrug transport
similar to conjugated polyketone reductase (PKR1)
syntenic homolog of ALG13_YEAST UDP-N-acetylglucosamine transferase subunit ALG13 (Asparagine linked glycosylation protein 13)
go_function transferase activity, transferring hexosyl groups; carbohydrate binding; go_process carbohydrate metabolism; lipid glycosylation
Predicted short chain-type dehydrogenase
hypothetical protein Glucose/ribitol dehydrogenase; go_function oxidoreductase activity; go_process metabolism
C-8 sterol isomerase (Delta-8--delta-7 sterol isomerase); go_component endoplasmic reticulum; go_function C-8 sterol isomerase activity; go_process ergosterol biosynthesis
protein involved in autophagocytosis during starvation
Autophagy-related protein 3 (Autophagy-related E2-like conjugation enzyme ATG3)
phospholipid:diacylglycerol acyltransferase
Phospholipid:diacylglycerol acyltransferase (PDAT) (Pombe LRO1 homolog 1); go_function phosphatidylcholine-sterol O-acyltransferase activity; go_process lipid metabolism
possible rho-like GTPase involved in secretory vesicle transport
go_component nucleus; go_process ribosome biogenesis and assembly
DNA binding protein involved in transcriptional regulation; go_component nucleus; go_process regulation of transcription, DNA-dependent
Has EST support; dispensable for premeiotic DNA synthesis and recombination, but required for tripartite synaptonemal complexes, haploidization, and spores
dispensable for premeiotic DNA synthesis and recombination, but required for tripartite synaptonemal complexes, haploidization, and spores; go_function protein kinase activity; ATP binding; protein serine/threonine kinase activity; go_process protein amino acid phosphorylation; cell cycle; go_function protein kinase activity; ATP binding; protein serine/threonine kinase activity; go_process protein amino acid phosphorylation; cell cycle
histone methyltransferase involved in gene regulation
Histone-lysine N-methyltransferase, H3 lysine-4 specific (COMPASS component SET1) (SET domain protein 1)
NADH-ubiquinone oxidoreductase 21 kDa subunit, mitochondrial precursor (Complex I-21KD) (CI-21KD)
NADH-ubiquinone oxidoreductase 21 kDa subunit, mitochondrial precursor (NUYM) (Complex I-21KD) (CI-21KD); go_function oxidoreductase activity, acting on NADH or NADPH; go_process electron transport
hypothetical signaling-associated PDZ domain containing protein
alpha-D-glucosidase (maltase) (alpha-amylase) (MALT); go_function alpha-amylase activity; go_process carbohydrate metabolism
go_function membrane alanyl aminopeptidase activity; go_process proteolysis and peptidolysis
hypothetical protein occurs in multiple copies through genome
Uridylate kinase (UK) (Uridine monophosphate kinase) (UMP kinase)
go_function oxidoreductase activity; go_process metabolism
go_function small GTPase regulator activity
Isocitrate lyase (Isocitrase) (Isocitratase) (ICL)
go_function catalytic activity; go_process metabolism
Negative regulator of the PHO system (Serine/threonine-protein kinase PHO85) (CaPHO85)
go_component cytoplasm; go_process intracellular protein transport
putative cell segregation machinery component
RNA recognition motif-containing protein
nucleolar RNA recognition motif-containing protein
go_component mitochondrion; go_function enzyme inhibitor activity; go_process negative regulation of nucleoside metabolism
ATPase inhibitor mitochondrial precursor
Required for invasion and pseudohyphae formation in response to nitrogen starvation
Regulatory Particle Non-ATPase. zf-C2H2 Zinc finger, C2H2 type; go_component nucleus; go_function nucleic acid binding; zinc ion binding
Acetyl-coenzyme A synthetase 2 [EC:6.2.1.1] [KO:K01895] (Acetate--CoA ligase 2) (Acyl-activating enzyme 2); go_function catalytic activity; go_process metabolism
heat shock protein 70, Hsp70 family (SSA2)
heat shock protein 70, Hsp70 family (SSA2) upregulated under oxygen limitation very low under aerobic conditions highest on XOL
go_function GTP binding; go_process cell cycle
eukaryotic ribosome biogenesis protein 1
Porin/voltage-dependent anion-selective channel protein
go_function voltage-gated ion-selective channel activity; go_component mitochondrial outer membrane; go_process anion transport
RNA polymerase II C-terminal domain kinase beta subunit
cyclin-related subunit of the kinase complex that phosphorylates the RPO21 CTD (carboxy-terminal domain) also called CTDK-I beta subunit
Geranylgeranyl transferase type II alpha subunit
Geranylgeranyl transferase type II alpha subunit (Type II protein geranyl-geranyltransferase alpha subunit) (GGTase-II-alpha) (PGGT) (YPT1/SEC4 proteins geranylgeranyltransferase alpha subunit); go_function protein prenyltransferase activity; go_process protein amino acid prenylation
go_component cytoplasm; go_function tRNA ligase activity; ATP binding; nucleic acid binding; go_process tRNA aminoacylation for protein translation
Glycolipid 2-alpha-mannosyltransferase (alpha-1,2-mannosyltransferase)
go_component membrane; go_function glycolipid 2-alpha-mannosyltransferase activity; go_process protein amino acid glycosylation
Multifunctional chaperone (14-3-3 family) Posttranslational modification, protein turnover
Brain Modulosignalin Homolog Multifunctional chaperone (14-3-3 family) Posttranslational modification, protein turnover; go_function protein domain specific binding
Fungal specific transcription factor; go_function DNA binding; transcription factor activity; zinc ion binding; go_process transcription; regulation of transcription, DNA-dependent
3-prime end of ExtraCellular Mutant protein
3-prime end of ExtraCellular Mutant protein (PST1)
lipoate biosynthesis protein; go_function catalytic activity; go_process protein modification
go_function protein transporter activity; go_component clathrin coat of trans-Golgi network vesicle; Golgi stack; go_process intracellular protein transport; protein complex assembly; intra-Golgi transport
succinate dehydrogenase membrane anchor subunit
go_function heme binding; go_component mitochondrial membrane; integral to membrane; go_process tricarboxylic acid cycle; electron transport
bud neck involved extremely serine rich protein
exosome 3'->5 exonuclease subunit ski4 (Csl4)
Has EST support; Represses the replication of double-stranded RNA viruses, protecting the host from the otherwise lethal effects of the virus
Represses the replication of double-stranded RNA viruses, protecting the host from the otherwise lethal effects of the virus
go_function DNA binding; go_process regulation of transcription, DNA-dependent
DNA-dependent ATPase MGS1 (Maintenance of genome stability protein 1) DNA-directed DNA polymerase ATPase
related to the helicase subunit of the Holliday junction resolvase
related to the helicase subunit of the Holliday junction resolvase; go_component nucleus; go_function ATP binding; nucleic acid binding; zinc ion binding; go_component nucleus; go_function ATP binding; nucleic acid binding; zinc ion binding
mitochondrial 37S ribosomal protein RSM24
Histone acetyltransferase transcription factor
involved in glucose repression of GAL4-regulated transcription
Histone acetyltransferase transcription factor involved in glucose repression of GAL4p-regulated transcription
hypothetical leucine rich repeat protein
go_function metalloendopeptidase activity; go_process proteolysis and peptidolysis
general RNA polymerase II transcription factor
general RNA polymerase II transcription factor (putative - by similarity); go_function structural constituent of cytoskeleton
subunit of ER protein- translocation complex
go_component integral to membrane; go_function protein transporter activity; go_process protein transport
go_component chromatin; nucleus; go_function DNA binding; ATP binding; nucleic acid binding; helicase activity; chromatin binding; go_process chromatin assembly or disassembly
Polyadenylate-binding protein, cytoplasmic and nuclear (Poly(A)-binding protein) (PABP) (ARS consensus binding protein ACBP-67) (Polyadenylate tail-binding protein)
Trehalose-phosphatase (Trehalose 6-phosphate phosphatase) (TPP); go_function alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity; trehalose-phosphatase activity; go_process trehalose biosynthesis
protein for resistance to o-dinitrobenzene, calcium, and zinc
conserved hypothetical protein with similarity to ROD1 Resistance to o-dinitrobenzene, calcium, and zinc
go_function hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; go_process nitrogen compound metabolism
Sporulation-specific protein 1 Serine/threonine protein kinase dispensable for mitosis, involved in middle/late stage of meiosis, required for spore wall formation; go_function protein kinase activity; ATP binding; go_process protein amino acid phosphorylation
interacts with Snf1p protein Putative GTPase activating protein
COQ6 monooxygenase, coenzyme Q biosynthesis
go_function monooxygenase activity; go_process aromatic compound metabolism
G-protein beta subunit-like protein containing WD repeats
go_component nucleus; go_function DNA binding
go_component nucleus; go_function transcription factor activity; go_process transcription initiation
Signal recognition particle 54 kDa protein
go_component signal recognition particle (sensu Eukaryota); go_function RNA binding; GTP binding; go_process SRP-dependent cotranslational protein-membrane targeting; protein targeting
go_component integral to membrane; go_function D-alanyl-D-alanine endopeptidase activity
AdoMet-dependent rRNA methyltransferase SPB1 (2'-O-ribose RNA methyltransferase) (S-adenosyl-L-methionine-dependent methyltransferase)
5',5'''-P-1,P-4-tetraphosphate phosphorylase II (Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase) (AP-4-A phosphorylase) (AP,A phosphorylase) (ATP adenylyltransferase)
Ubiquinol-cytochrome c reductase complex 14 kDa protein (Complex III subunit VII)
Ubiquinol-cytochrome c reductase complex 14 kDa protein (Complex III subunit VII) (QCR7); go_function ubiquinol-cytochrome-c reductase activity; go_process electron transport; mitochondrial electron transport, ubiquinol to cytochrome c
mitochondrial dicarboxylate transport protein
go_component membrane; go_function binding; go_process transport
mitochondrial 37S ribosomal protein MRP4
longevity-assurance protein Acyl-CoA-dependent ceramide synthase; go_component integral to membrane
go_process intracellular protein transport
go_component F-actin capping protein complex; go_function actin binding; go_process actin cytoskeleton organization and biogenesis
Ubiquitin fusion degradation protein 4; go_component intracellular; go_function ubiquitin-protein ligase activity; go_process protein modification; ubiquitin cycle
Splicing component that associates with the yeast U1 small nuclear ribonucleoprotein particle
go_component cytoskeleton; go_process actin filament polymerization
transcriptional activator for allantoin and GABA catabolic genes; go_component nucleus; go_function transcription factor activity; zinc ion binding; DNA binding; go_process regulation of transcription, DNA-dependent; transcription
DHHC-type heme binding zing finger protein; go_function metal ion binding
N2,N2-dimethylguanosine-specific tRNA methyltransferase [; go_function RNA binding; tRNA (guanine-N2-)-methyltransferase activity; go_process tRNA processing
Cruciform cutting endonuclease 1, mitochondrial precursor
phosphopantothenoylcysteine decarboxylase
signal peptidase subunit; go_function serine-type peptidase activity; go_process proteolysis and peptidolysis
3-oxoacyl-[acyl- carrier-protein] reductase
Translationally controlled tumor protein homolog (TCTP)
go_component cytoplasm; go_function molecular function unknown
go_component membrane; go_function serine-type peptidase activity; dipeptidyl-peptidase IV activity; go_process proteolysis and peptidolysis
histidine kinase osmosensor Osmolarity two-component system protein SLN1
Sensory transduction histidine kinase; go_component membrane; go_function two-component response regulator activity; DNA binding; two-component sensor molecule activity; ATP binding; go_process two-component signal transduction system (phosphorelay); regulation of transcription, DNA-dependent; signal transduction
Has EST support; similar to cell surface flocculin similar to HYR1
go_function N-acetyltransferase activity
Up in StarVation Zn-finger strongly conserved (RGM1); go_component nucleus; go_function nucleic acid binding; zinc ion binding; go_component nucleus; go_function nucleic acid binding; zinc ion binding
go_component microtubule associated complex; go_function motor activity; ATP binding
mitochondrial groEL-type heat shock protein
zf-C2H2 Zinc finger, C2H2 type calcineurin responsive zinc-finger; go_component nucleus; go_function nucleic acid binding; zinc ion binding
Permease of the major facilitator superfamily
go_component membrane; go_function mating-type factor pheromone receptor activity
fungal pheromone mating factor STE2G-protein-coupled receptor
pyruvate decarboxylase [EC:4.1.1.1] [KO:K01568]
Putative mannosyltransferase of the KRE2 family; go_component membrane; go_function glycolipid 2-alpha-mannosyltransferase activity; go_process protein amino acid glycosylation
histone deacetylase and transcriptional regulator
Suppressor of Defective Silencing 3Functions are similar to those of SIN3 and RPD3
multifunctional pyrimidine biosynthesis protein (PYR1)
Carbamoyl-phosphate synthase; go_component cytoplasm; go_function catalytic activity; amino acid binding; carboxyl- and carbamoyltransferase activity; ligase activity; carbamoyl-phosphate synthase activity; ATP binding; go_process amino acid metabolism; metabolism; nitrogen compound metabolism; arginine biosynthesis; pyrimidine base biosynthesis
go_function cation transporter activity; go_process cation transport
hypothetical beta-1,6-N-acetylglucosaminyltransferase
Has EST support; contains WSC domain similar to Protein VHS2 (Viable in a HAL3 SIT4 background protein 2)
DNA-binding proteins Bright/BRCAA1/RBP1 and related proteins containing BRIGHT domain
go_component integral to membrane; go_function molecular function unknown
Zn_clus Fungal Zn(2)-Cys(6) binuclear cluster domain
Zn-finger domain highly conserved has 105 hits in genome; go_component nucleus; go_function transcription factor activity; zinc ion binding; go_process regulation of transcription, DNA-dependent
go_component cytoskeleton; go_process regulation of actin filament polymerization
phosphoglucoisomerase upregulated 2-3 fold on XOL relative to XA; go_function glucose-6-phosphate isomerase activity; go_process gluconeogenesis; glycolysis
go_component membrane; go_function cation transporter activity; go_process cation transport
protein required for amino acid permease transport from the Golgi to the cell surface
beta-hydroxysteroid dehydrogenase type 3
Catalytic subunit of the main cell cycle cyclin-dependent kinase; go_function protein kinase activity; ATP binding; go_process protein amino acid phosphorylation
short-chain dehydrogenase/reductase (SDR) family protein
high copy suppressor of a cyclic AMP-dependent protein kinase mutant
similar to SFL1; go_component nucleus; go_function transcription factor activity; go_process regulation of transcription, DNA-dependent; go_component nucleus; go_function transcription factor activity; go_process regulation of transcription, DNA-dependent
mitochondrial protein of the CDC48/PAS1/SEC18 ATPase family
go_component nucleus; go_function DNA binding; go_process nucleosome assembly
sugar transporter, high affinity, putative
Xylose UpTake (tentative); go_component integral to membrane; go_function transporter activity; go_process transport
hydrolyzes inositolphosphosphingolipids (IPC, MIPC, M(IP)2C) as well as sphingomyelin
go_component membrane; integral to membrane; go_function ATP binding; go_process transport
oligomycin resistance ATP-dependent permease
go_function nucleic acid binding; ribonuclease H activity
go_function lyase activity; hydro-lyase activity; go_process metabolism
Vacuolar ATP synthase subunit B (V-ATPase B subunit) (Vacuolar proton pump B subunit) (V-ATPase 57 kDa subunit)
go_component proton-transporting two-sector ATPase complex; go_function ATP binding; hydrogen-transporting ATP synthase activity, rotational mechanism; hydrogen-transporting ATPase activity, rotational mechanism; go_process ATP synthesis coupled proton transport; ATP biosynthesis
go_function Ras GTPase activator activity; go_process small GTPase mediated signal transduction
go_function transcription regulator activity
translation initiation factor eIF3 subunit
go_component proteasome core complex (sensu Eukaryota); go_function endopeptidase activity; go_process ubiquitin-dependent protein catabolism
NADH-ubiquinone oxidoreductase 49 kDa subunit, mitochondrial precursor
NADH-ubiquinone oxidoreductase 49 kDa subunit, mitochondrial precursor (NUCM)(NUO); go_function electron transporter activity; go_process electron transport
go_function ubiquitin conjugating enzyme activity; go_process protein modification; ubiquitin cycle
go_component cytoplasm; go_process apoptosis
go_function GTP binding; translation initiation factor activity; go_process protein biosynthesis; translational initiation
mitochondrial translation initiation factor 2
go_function nucleic acid binding; zinc ion binding
go_function subtilase activity; go_process proteolysis and peptidolysis
go_component nucleus; go_function nucleic acid binding; zinc ion binding
go_component transcription factor complex; go_function RNA polymerase II transcription factor activity; go_process transcription initiation
go_component membrane; go_function mannosyltransferase activity; go_process O-linked glycosylation
Dolichyl-phosphate-mannose--protein mannosyltransferase 1
P-type ATPase involved in Na+ efflux; go_component membrane; go_function ATP binding; hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; catalytic activity; go_process cation transport; metabolism
catechol o- methyltransferase (COMT); go_function O-methyltransferase activity
go_process intracellular signaling cascade
Gamma-butyrobetaine dioxygenase (Gamma-butyrobetaine,2-oxoglutarate dioxygenase) (Gamma-butyrobetaine hydroxylase) (Gamma-BBH)
go_function protein translocase activity; go_component mitochondrial inner membrane; go_process protein-mitochondrial targeting
asparaginyl-tRNA synthetase (SYNM); go_component cytoplasm; go_function tRNA ligase activity; ATP binding; go_process tRNA aminoacylation for protein translation
Asparaginyl-tRNA synthetase, cytoplasmic (Asparagine--tRNA ligase) (AsnRS)
Asparaginyl-tRNA synthetase, cytoplasmic (Asparagine--tRNA ligase) (AsnRS) (SYNC); go_component cytoplasm; go_function tRNA ligase activity; ATP binding; nucleic acid binding; go_process tRNA aminoacylation for protein translation
go_function pepsin A activity; go_process proteolysis and peptidolysis
pyrazinamidase Nicotinamidase (Nicotine deamidase) (NAMase); go_function catalytic activity; go_process metabolism
Dead-box family helicase required for mRNA export from nucleus
Dead-box family helicase required for mRNA export from nucleus ATP-dependent RNA helicase DOB1 (mRNA transport regulator MTR4); go_function nucleic acid binding; helicase activity; ATP binding
go_function serine carboxypeptidase activity; go_process proteolysis and peptidolysis
Serine hydroxymethyltransferase, mitochondrial precursor (Serine methylase)
go_function glycine hydroxymethyltransferase activity; go_process glycine metabolism; L-serine metabolism
Nit protein, nitrilase superfamily member; go_function hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; go_process nitrogen compound metabolism
go_component peroxisome; integral to membrane; go_process peroxisome matrix protein import, docking
go_function oxidoreductase activity; go_process electron transport
endocytosis and membrane growth and polarity
go_component actin cytoskeleton; go_function structural constituent of cytoskeleton
protein threonine/tyrosine kinase; go_function protein kinase activity; ATP binding; go_process protein amino acid phosphorylation
multicopy suppressor of clathrin deficiency
Prohibitins and stomatins of the PID superfamily
Sterol O-acyltransferase 2 (Sterol-ester synthase 2)
similar to NAS6, an ankyrin repeat protein that interacts with the 19S regulatory particle of the 26S proteasome
Predicted quinone oxidoreductase (QOR3); go_function alcohol dehydrogenase activity, zinc-dependent; zinc ion binding
Acyl-CoA desaturase (Stearoyl-CoA desaturase) (Fatty acid desaturase) (Delta(9)-desaturase); go_function oxidoreductase activity
subunit of SWI/SNF transcription activation complex
73 kDa subunit of the SWI/SNF transcription activation complex, homolog of Rsc6p subunit of the RSC chromatin remodeling complex
cAMP-dependent protein kinase catalytic subunit
DNA-directed RNA polymerase II small subunit 9 participating in elongation and formed of two conserved zinc domains (DNA-directed RNA polymerase II 14.2 kDa polypeptide) (B12.6); go_function DNA binding; transcription factor activity; DNA-directed RNA polymerase activity; go_process RNA elongation; regulation of transcription, DNA-dependent; transcription
putative mitochondrial 54S ribosomal protein MNP1
fungal specific zinc-finger transcription factor
Quinic acid utilization activator fungal specific zinc-finger transcription factor; go_component nucleus; go_function transcription factor activity; zinc ion binding; DNA binding; go_process regulation of transcription, DNA-dependent; transcription
3-oxoacid CoA-transferase Succinyl-CoA:alpha-ketoacid-CoA transferase
go_function CoA-transferase activity; go_process metabolism
3-dehydroquinate dehydratase 1 (3-dehydroquinase 1) (Type II DHQase 1)
go_function 3-dehydroquinate dehydratase activity; go_process aromatic amino acid family biosynthesis
DNA-directed RNA polymerase I subunit A12 (RPA12)
go_function DNA binding; transcription factor activity; DNA-directed RNA polymerase activity; go_process RNA elongation; regulation of transcription, DNA-dependent; transcription
phycocyanin alpha-subunit phycocyanobilin lyase
T-complex protein 1, epsilon subunit (TCP-1-epsilon) (CCT-epsilon)
actin-related protein3; go_component actin cytoskeleton; go_function structural constituent of cytoskeleton
go_function phosphotransferase activity, alcohol group as acceptor
go_function RNA-3'-phosphate cyclase activity
go_function transcription initiation factor activity; go_component transcription factor TFIID complex; go_process transcription initiation
go_component nucleus; go_process mitosis; chromosome condensation
Has EST support; performs the last step in heme biosynthesis
Performs last step in heme biosynthesis pathway, inserting ferrous iron into protoporphyrin IX; go_function ferrochelatase activity; go_process heme biosynthesis; go_function ferrochelatase activity; go_process heme biosynthesis
go_component intracellular; go_function nucleic acid binding
go_function DNA binding; ATP binding; nucleic acid binding; helicase activity; type III site-specific deoxyribonuclease activity; go_process DNA restriction-modification system
Vacuolar ATP synthase subunit G (V-ATPase G subunit) (Vacuolar proton pump G subunit) (V-ATPase 13 kDa subunit)
Meiotic Sister-Chromatid recombination aldehyde dehydrogenase
aldehyde dehydrogenase NADP-dependent glyceraldehyde-3-phosphate dehydrogenase (GAPN) (ALD1); go_function oxidoreductase activity; go_process metabolism
go_component membrane; go_function nucleobase transporter activity; go_process nucleobase, nucleoside, nucleotide and nucleic acid transport
precocious dissociation of sister chromatids
mitochondrial 54S ribosomal protein YmL7/YmL5
similar to the Saccharomyces pombe and mammalian Chk1 checkpoint kinases
similar to the Saccharomyces pombe and mammalian Chk1 checkpoint kinases; go_function protein kinase activity; ATP binding; go_process protein amino acid phosphorylation; go_function protein kinase activity; ATP binding; go_process protein amino acid phosphorylation
go_component membrane; go_function ion channel activity; go_process ion transport
Gtp-binding protein of the rho subfamily of ras-like proteins; go_function GTP binding; go_process small GTPase mediated signal transduction
mitochondrial heat shock protein of the HSP70 family upregulated 15 fold under aerobic conditions
Nuclear-encoded mitochondrial protein member of the heat shock protein 70 (HSP70) family most similar to E. coli DnaK protein acts as a chaperone for protein import across the inner membrane subunit of Endo.SceI endonuclease
go_function oxidoreductase activity, acting on CH-OH group of donors; go_process carbohydrate metabolism
lysophospholipase B; go_function phospholipase activity; go_process phospholipid catabolism
lactose regulatory protein (LAC9); go_component nucleus; go_function transcription factor activity; zinc ion binding; go_process regulation of transcription, DNA-dependent
ATP-dependent DNA helicase (ADD1.1); go_function nucleic acid binding; helicase activity; ATP binding
translational activator of GCN4 through activation of GCN2 in response to starvation
DNA-binding protein (Carbon catabolite repressor)
transcription factor involved in glucose repression; go_component nucleus; go_function nucleic acid binding; zinc ion binding
hypothetical protein containing von Willebrand factor and highly repetitive sequences
Has EST support. could be due to repetitive nature
beta-glucosidase precursor glycosyl hydrolase family 3; go_function hydrolase activity, hydrolyzing O-glycosyl compounds; go_process carbohydrate metabolism
Sugar transporter similar to Candida intermedia gxf1; go_component integral to membrane; go_function transporter activity; go_process transport