Scheffersomyces stipitis CBS 6054 chromosome 4, complete sequence.
Scheffersomyces stipitis CBS 6054 (Pichia stipitis CBS 6054)
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
Genome sequence of the lignocellulose-bioconverting and xylose-fermenting yeast Pichia stipitis
Submitted (05-JUN-2017) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (12-DEC-2006) US DOE Joint Genome Institute, 2800 Mitchell Drive B100, Walnut Creek, CA 94598-1698, USA
PROVISIONAL REFSEQ: This record has not yet been subject to final\nNCBI review. The reference sequence is identical to CP000498.\nURL -- http://www.jgi.doe.gov/pichia\nJGI Project ID: 3634480\nSource DNA was provided by Jose Laplaza and Thomas Jeffries\n(twjeffri@wisc.edu)\nStock culture is available from Cletus P Kurtzman\n(kurtsman@ncaur.usda.gov)\nContacts: Thomas Jeffries (twjeffri@wisc.edu)\n Paul Richardson (microbes@cuba.jgi-psf.org)\nAnnotation done by JGI-PGF\nManual curation done by the P. stipitis User Community\nFinishing done by JGI-Stanford Human Genome Center\n(www-shgc.stanford.edu)\nFalse join at 275203\nThe finished chromosome has no gaps. The sequence has less than one\nerror in 100,000 bp.\nThe JGI and collaborators endorse the principles for the\ndistribution and use of large scale sequencing data adopted by the\nlarger genome sequencing community and urge users of this data to\nfollow them. It is our intention to publish the work of this\nproject in a timely fashion and we welcome collaborative\ninteraction on the project and analysis.\n(http://www.genome.gov/page.cfm?pageID=10506376).\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: INSDC submitter\nAnnotation Status :: Full annotation\nAnnotation Pipeline :: Eukaryotic Annotation Propagation Pipeline\n##Genome-Annotation-Data-END##\nCOMPLETENESS: full length.
hypothetical ORF present in 3-4 copies in genome. Not conserved. Tandem repeat.
Glycoside hydrolase, family 10 Endo-1,4-beta-xylanase precursor (Xylanase) Exoglucanase/xylanase precursor
Includes: Exoglucanase (Exocellobiohydrolase) (1,4-beta-cellobiohydrolase) (Beta-1,4-glycanase CEX) Endo-1,4-beta-xylanase B (Xylanase B) (XLNA)
Glycoside hydrolase, family 10 Endo-1,4-beta-xylanase precursor (Xylanase) Exoglucanase/xylanase precursor [Includes: Exoglucanase (Exocellobiohydrolase) (1,4-beta-cellobiohydrolase) (Beta-1,4-glycanase CEX) Endo-1,4-beta-xylanase B (Xylanase B)] (XYN) (GUX) (XLN); go_function hydrolase activity, hydrolyzing O-glycosyl compounds; go_process carbohydrate metabolism
go_function alcohol dehydrogenase activity, zinc-dependent; zinc ion binding
Granaticin polyketide synthase putative ketoacyl reductase 2
Granaticin polyketide synthase putative ketoacyl reductase 2 similar to glucose 1-dehydrogenase (DHG3) (bacterial); go_function oxidoreductase activity; go_process metabolism
putative glycosyl phosphatidylinositol protein
Ferric reductase, NADH/NADPH oxidase transmembrane component (7 domains)
Ferric reductase, NADH/NADPH oxidase transmembrane component (FRP1) (FRP2) (FRE11) (FRE5) (FRE2); go_function oxidoreductase activity; go_component membrane; go_process electron transport
Suppressor of Yeast Profilin deletion GABA-B ion channel receptor subunit GABABR1 and related subunits, G-protein coupled receptor superfamily
go_component endoplasmic reticulum; integral to membrane; go_process intracellular protein transport; apoptosis
go_function metal ion transporter activity; go_component membrane; go_process metal ion transport
go_function DNA binding; transcription coactivator activity; go_process regulation of transcription, DNA-dependent
Probable alpha-1,6-mannosyltransferase MNN10 (Mannan polymerase II complex MNN10 subunit) (M-Pol II subunit MNN10) (Bud emergence delay protein 1); go_function transferase activity, transferring hexosyl groups; go_component integral to membrane
component of SWI/SNF global activator complex
Global transcription activator that acts in complex with Snf2p, Snf5p, Snf6p, and Swi3p to assist gene-specific activators involved in the regulation of expression of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2
go_function oxidoreductase activity; go_process electron transport
Histidine biosynthesis trifunctional protein
Has EST support; Includes: Phosphoribosyl-AMP cyclohydrolase Phosphoribosyl-ATP pyrophosphohydrolase Histidinol dehydrogenase (HDH)
Includes: Phosphoribosyl-AMP cyclohydrolase Phosphoribosyl-ATP pyrophosphohydrolase Histidinol dehydrogenase (HDH); go_function histidinol dehydrogenase activity; phosphoribosyl-AMP cyclohydrolase activity; phosphoribosyl-ATP diphosphatase activity; go_process histidine biosynthesis; go_function histidinol dehydrogenase activity; phosphoribosyl-AMP cyclohydrolase activity; phosphoribosyl-ATP diphosphatase activity; go_process histidine biosynthesis
chaperonin of the HSP70 family heat shock protein 70 (SSA3) (Heat shock protein YG100)
Stress-seventy subfamily A Heat shock protein SSA1 (Heat shock protein YG100)
Suppressor of the cold-sensitive snRNP biogenesis mutant brr1-1
ATP-dependent RNA helicase Suppressor of the cold-sensitive snRNP biogenesis mutant brr1-1; go_function nucleic acid binding; helicase activity; ATP binding
delta 1-pyrroline-5-carboxylate reductase
go_function pyrroline-5-carboxylate reductase activity; go_process proline biosynthesis
conserved hypothetical protein DNA-binding protein jumonji/RBP2/SMCY, contains JmjC domain
go_function DNA binding; go_process regulation of transcription, DNA-dependent
F(1)F(0)-ATPase complex beta subunit, mitochondrial; go_component proton-transporting two-sector ATPase complex; go_function ATP binding; hydrogen-transporting ATP synthase activity, rotational mechanism; hydrogen-transporting ATPase activity, rotational mechanism; go_process ATP synthesis coupled proton transport; ATP biosynthesis
zinc metallo-protease that catalyzes the first step of N-terminal processing of the yeast a-factor precursor; go_component membrane; go_function metalloendopeptidase activity; go_process proteolysis and peptidolysis
has a role in 5' splice site recognition
Glycolipid anchored surface protein 4 precursor
Glycine-rich cell wall structural protein precursor
hypothetical Glycine-rich cell wall structural protein precursor
go_function peptidase activity; go_process proteolysis and peptidolysis
go_component integral to membrane; go_function solute:hydrogen antiporter activity; go_process regulation of pH
vacuolar ATPase V0 domain subunit d (36 kDa)
go_function hydrogen-transporting ATP synthase activity, rotational mechanism; hydrogen-transporting ATPase activity, rotational mechanism; go_component proton-transporting two-sector ATPase complex; go_process ATP synthesis coupled proton transport
go_function DNA binding; ATP binding; nucleic acid binding; helicase activity
go_function transaminase activity; go_process biosynthesis
mitochondrial 37S ribosomal protein MRPS17
go_component intracellular; ribosome; go_function structural constituent of ribosome; go_process protein biosynthesis
go_component membrane; go_function ion channel activity; go_process ion transport
go_component membrane; go_function nucleoside transporter activity; go_process transport
go_function oxidoreductase activity; go_process metabolism
go_component membrane; go_process transport
Has EST support; weak similarity to acid phosphatase
go_function protein transporter activity; go_component nucleus; nuclear pore; cytoplasm; go_process protein-nucleus import, docking
Ca2+-modulated nonselective cation channel polycystin
go_function nucleotidyltransferase activity; go_process biosynthesis
go_component intracellular; go_function ubiquitin-protein ligase activity; go_process protein modification; ubiquitin cycle
go_function catalytic activity; go_process metabolism
Has EST support; similar to related proteins containing BRIGHT domain
fungal Zn(2)-Cys(6) binuclear cluster domain DNA-binding proteins Bright/BRCAA1/RBP1 and related proteins containing BRIGHT domain; go_component nucleus; go_function transcription factor activity; zinc ion binding; go_process regulation of transcription, DNA-dependent; go_component nucleus; go_function transcription factor activity; zinc ion binding; go_process regulation of transcription, DNA-dependent
go_function translation initiation factor activity; go_process translational initiation
go_function ATP binding; go_process mismatch repair
go_function O-sialoglycoprotein endopeptidase activity; go_process proteolysis and peptidolysis
go_component membrane; go_function binding; go_process transport
go_function caspase activity; go_process proteolysis and peptidolysis
go_function catalytic activity; nutrient reservoir activity
go_function RNA binding; go_process RNA processing
go_component cytoplasm; go_function shikimate kinase activity; ATP binding; 3-dehydroquinate dehydratase activity; shikimate 5-dehydrogenase activity; 3-dehydroquinate synthase activity; go_process amino acid biosynthesis; aromatic amino acid family biosynthesis; aromatic amino acid family biosynthesis, shikimate pathway
pentafunctional arom polypeptide, shikimate 5-dehydrogenase
large protein with a conserved N-terminal domain, a central AAA ATPase domain composed of 6 tandem AAA protomers, and a C-terminal M-domain midas sequence motif-containing protein
longevity-assurance protein Acyl-CoA-dependent ceramide synthase
go_function GTP binding; go_process small GTPase mediated signal transduction
plays a role in transcriptional elongation
Required for LacZ RNA expression from certain plasmids; suppressor of the Transcriptional (T) defect of Hpr1 (H) by Overexpression (O); plays a role in transcription elongation by RNA polymerase II; plays a role in transcriptional elongation
THO2 plays a role in transcriptional elongation
Strongly-conserved Zn-finger binding protein (TFIIIA)
transcription initiation factor TFIIIA; go_component nucleus; go_function nucleic acid binding; zinc ion binding
go_function RNA binding; RNA methyltransferase activity; go_process RNA processing
mitochondrial 37S ribosomal protein MRP51
go_function protein kinase activity; ATP binding; go_process protein amino acid phosphorylation
go_component membrane; go_function molecular function unknown
go_component nucleus; go_function DNA binding
go_component tRNA-intron endonuclease complex; go_function tRNA-intron endonuclease activity; go_process tRNA splicing
concentrative Na+-nucleoside cotransporte
go_component membrane; go_function nucleoside:sodium symporter activity; go_process transport
cell morphogenesis, cytoskeletal regulation and bud formation
go_function acyl-CoA thioesterase activity; go_process acyl-CoA metabolism
Vacuolar sorting protein VPS33/slp1 (Sec1 family)
vacuolar sorting protein essential for vacuolar morphogenesis and function; go_function protein transporter activity; go_process protein secretion
pre-mRNA cleavage and polyadenylation factor I component
Isocitrate dehydrogenase [NADP], mitochondrial precursor (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP) (CtIDP1)
phosphopantothenoylcysteine decarboxylase
fumarate reductase flavoprotein subunit [EC:1.3.99.1] (FRD1) (NADH-dependent fumarate reductase) (FAD-dependent oxidoreductase FRDS) [KO:K00238]; go_function oxidoreductase activity; go_process electron transport
cleavage and polyadenylation specificity factor
go_function cysteine-type endopeptidase activity; go_process proteolysis and peptidolysis
Synaptic vesicle transporter SVOP (MDR1)
Chitin biosynthesis protein CHS5 (CAL3 protein)
chitin biosynthesis protein Involved in chitin synthase III activity, also required for homozygosis in the first stages of mating (Yong-Su Jin[2006-01-06 09:35:48]); go_component intracellular
vacuolar H-ATPase 14 kDa subunit (subunit F) of the catalytic (V1) sector
calcium-binding mitochondrial carrier mitochondrial ADP/ATP carrier protein; go_component membrane; go_function binding; go_process transport
member of complex that acts at ARS's to initiate replication
DNA replication licensing factor MCM3 (Minichromosome maintenance protein 3); go_function DNA binding; ATP binding; DNA-dependent ATPase activity; go_process DNA replication initiation
NADH-cytochrome b-5 reductase (MCR1); go_function oxidoreductase activity; go_process electron transport
Pantothenate transporter FEN2 (Fenpropimorph resistance protein 2)
beta-1,6-N-acetylglucosaminyltransferase, contains WSC domain
involved in telomere length regulation; go_function phosphotransferase activity, alcohol group as acceptor; go_function phosphotransferase activity, alcohol group as acceptor
Aminomethyl transferase Required for metabolizing glycine as a nitrogen source; go_function aminomethyltransferase activity
NAD/NADP dependent alcohol dehydrogenase
part of the signal recognition particle (SRP) ribonucleoprotein (RNP) complex
part of the signal recognition particle (SRP) ribonucleoprotein (RNP) complex that functions in protein targeting to the endoplasmic reticulum (ER) membrane
NADPH dehydrogenase (old yellow enzyme); go_function oxidoreductase activity; go_process electron transport
Protein required for assembly of ubiquinol cytochrome-c reductase complex (cytochrome bc1 complex)
involved in cytochrome-c reductase assembly
go_function glycerophosphodiester phosphodiesterase activity; go_process glycerol metabolism
Has EST support; hydrolyzes the pyrophosphate linkage in NADH and related nucleotides
hydrolyzes the pyrophosphate linkage in NADH and related nucleotides
DEAD-box ATP-dependent RNA helicase; go_function nucleic acid binding; helicase activity; ATP binding
go_function pseudouridylate synthase activity; go_process tRNA processing
Has EST support; protein is highly expressed but a mix-up of various motifs
protein is highly expressed but a mix-up of various motifs
Fe-S oxidoreductase Ribosomal protein L5
Alpha-1,3-mannosyltransferase ALG2 (GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase); go_process biosynthesis
go_function protein transporter activity; go_process intracellular protein transport
protein required for asparagine-linked oligosaccharide assembly
Specifies addition of the terminal alpha 1,2-Man to the Man5GlcNAc2-PP-dolichol N-Glycosylation intermediate; go_process biosynthesis
go_function metalloexopeptidase activity; go_process proteolysis and peptidolysis
go_function structural molecule activity
go_component membrane; go_function amino acid-polyamine transporter activity; go_process amino acid transport
chloride channel, possibly voltage gated
go_component membrane; go_function voltage-gated chloride channel activity; go_process chloride transport
hypothetical beta-1,6-N-acetylglucosaminyltransferase, contains WSC domain
Dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase
Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase (Dol-P-Man dependent alpha(1-3)-mannosyltransferase) (HM-1 killer toxin resistance protein); go_component endoplasmic reticulum; integral to membrane; go_function mannosyltransferase activity
putaative nucleolar protein required for 60S ribosome biogenesis
go_component peroxisomal membrane; go_process peroxisome division
go_component membrane; go_function bile acid:sodium symporter activity; go_process sodium ion transport
3-hydroxyisobutyrate dehydrogenase-like protein
go_function phosphogluconate dehydrogenase (decarboxylating) activity; go_process pentose-phosphate shunt; go_function phosphogluconate dehydrogenase (decarboxylating) activity; go_process pentose-phosphate shunt
go_function catalytic activity; go_process protein modification
34-kDa subunit of RNA polymerase III (C)
go_component nucleus; go_function DNA binding; DNA-directed RNA polymerase activity; go_process transcription
go_function amino acid binding; carboxyl- and carbamoyltransferase activity; go_process amino acid metabolism
NADPH-dependent methylglyoxal reductase GRE2
induced by osmotic stress similar to dihydroflavonol 4-reductase from plants
go_function tRNA ligase activity; ATP binding; go_process tRNA aminoacylation for protein translation
go_component membrane; go_function cation transporter activity; go_process cation transport
go_component intracellular; nucleus; go_process RNA processing; mRNA processing
go_function rRNA (adenine-N6,N6-)-dimethyltransferase activity; rRNA methyltransferase activity; go_process rRNA modification
component of SWI/SNF global transcription activator complex
Transcription regulatory protein SNF2 (SWI/SNF complex component SNF2) (Regulatory protein SWI2) (Regulatory protein GAM1) (Transcription factor TYE3); go_function DNA binding; ATP binding; nucleic acid binding; helicase activity
go_function GTP binding; go_process cell cycle
2-dehydro-3-deoxy- phosphoheptonate aldolase
DAHP synthase a.k.a. phospho-2-dehydro-3-deoxyheptonate aldolase, phenylalanine-inhibited phospho-2-keto-3-deoxyheptonate aldolase 2-dehydro-3-deoxyphosphoheptonate aldolase 3-deoxy-D-arabine-heptulosonate-7-phosphate synthase; go_process biosynthesis
go_function cysteine-type endopeptidase activity; ubiquitin thiolesterase activity; go_process ubiquitin-dependent protein catabolism
chitinase endochitinase 1 precursor (CHI1); go_function hydrolase activity; go_process metabolism
phosphatidylinositol 3-phosphate 5-kinase
go_function zinc ion binding; 1-phosphatidylinositol-4-phosphate 5-kinase activity
T-SNARE affecting a late Golgi compartment protein 2
O-dinitrobenzene, calcium and zinc resistance protein
Antagonist of MEN (Mitotic Exit Network)
go_component nucleus; go_function DNA binding; zinc ion binding; go_process transcription
go_function oxidoreductase activity; go_process electron transport; metabolism
RNA exonuclease NGL2 (Carbon catabolite repressor protein 4 homolog)
completion of mitosis and maintenance of ploidy
Part of small ribosomal subunit (SSU) processosome (contains U3 snoRNA)
Has EST support; Rrp5p is the only ribosomal RNA processing trans-acting factor that is required for the synthesis of both 18S and 5.8S rRNAs
Rrp5p is the only ribosomal RNA processing trans-acting factor that is required for the synthesis of both 18S and 5.8S rRNAs; go_function RNA binding; go_function RNA binding
GATA-family of DNA binding proteins-like protein
go_component nucleus; go_function transcription factor activity; go_process regulation of transcription, DNA-dependent; go_component nucleus; go_function transcription factor activity; go_process regulation of transcription, DNA-dependent
predicted molecular weight of 67 kD; go_component nucleus; go_function transcription factor activity; go_process regulation of transcription; go_component nucleus; go_function transcription factor activity; go_process regulation of transcription
go_component membrane; go_function ATP binding; hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
Lanosterol synthase (Oxidosqualene--lanosterol cyclase) (2,3-epoxysqualene--lanosterol cyclase) (OSC)
Glycoside hydrolase, family 38 vacuolar alpha mannosidase
go_function alpha-mannosidase activity; go_process carbohydrate metabolism
go_function copper, zinc superoxide dismutase activity; metal ion binding; go_process superoxide metabolism
go_function RNA binding; endoribonuclease activity
Drs2 Neo1 Family aminophospholipid-translocating ATPase; go_function catalytic activity; go_process metabolism
GPI transamidase complex, GPI16/PIG-T component, involved in glycosylphosphatidylinositol anchor biosynthesis Cell wall/membrane/envelope biogenesis; go_component integral to membrane; GPI-anchor transamidase complex
go_function disulfide oxidoreductase activity; go_process electron transport
NADH dehydrogenase, internal, ubiquinone
pyridine nucleotide-disulphide oxidoreductase family
Has EST support; involved in vacuolar polyphosphate accumulation
involved in vacuolar polyphosphate accumulation
mitochondrial 54S ribosomal protein YmL22
COP9 signalosome subunit 5A / CSN subunit 5A (CSN5A) / c-JUN coactivator protein AJH2, putative (AJH2)
clathrin assembly complex beta adaptin component
go_function nuclease activity; go_process DNA repair
go_function gamma-glutamyltransferase activity
Opaque-specific ABC transporter CDR3 Pleiotropic drug resistance proteins (PDR1-15), ABC superfamily; go_component membrane; go_function ATP binding; go_process transport
go_component nucleus; go_function damaged DNA binding; go_process nucleotide-excision repair
go_function translation release factor activity; go_process translational termination
Nucleoporin NUP84 (Nuclear pore protein NUP84)
go_component nuclear pore; go_process transport
go_process intracellular signaling cascade
go_component tubulin; go_function GTPase activity; GTP binding; go_process microtubule polymerization
Pyridoxal reductase (PL reductase) (PL-red)
go_function chitin synthase activity; go_process chitin biosynthesis
adenine aminohydrolase (adenine deaminase)
go_function deaminase activity; go_process purine ribonucleoside monophosphate biosynthesis
go_function subtilase activity; go_process proteolysis and peptidolysis
farnesyl-diphosphate farnesyltransferase
Farnesyl-diphosphate farnesyltransferase (Squalene synthetase) (SQS) (SS) (FPP:FPP farnesyltransferase); go_function transferase activity; go_process biosynthesis
DNA-directed RNA polymerase II regulator
Protein with similarity to aldo-keto reductases
go_function damaged DNA binding; ATP binding; go_process mismatch repair
translational elongation factor EF-1 alpha
translational elongation factor EF-1 alpha (EF1A); go_component cytoplasm; go_function translation elongation factor activity; go_process protein biosynthesis; translational elongation
Has EST support; acts in a checkpoiint pathway during S-phase
DNA polymerase II complex component Nucleotide excision repair factor NEF2, RAD4/CUT5 component; acts in a checkpoiint pathway during S-phase; go_component intracellular; go_component intracellular
go_function carrier activity; steroid binding; go_process transport
go_component nucleus; go_function transcription factor activity; zinc ion binding; DNA binding; go_process regulation of transcription, DNA-dependent; transcription
go_function protein translocase activity; go_component mitochondrial inner membrane presequence translocase complex; go_process protein transport
glucosamine 6-phosphate synthetase and asparagine synthase-like protein
Vacuolar ATP synthase subunit C (V-ATPase C subunit) (Vacuolar proton pump C subunit) (V-ATPase 42 kDa subunit)
go_component proton-transporting two-sector ATPase complex; go_function ATP binding; hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; go_process ATP synthesis coupled proton transport
Inorganic pyrophosphatase (Pyrophosphate phospho-hydrolase) (PPase)
go_function pyrophosphatase activity; go_component membrane; go_process metabolism
go_function oxidoreductase activity; FAD binding; go_process tRNA processing
go_component nucleus; go_function transcription factor activity; zinc ion binding; go_process regulation of transcription, DNA-dependent
go_component membrane; go_function calcium ion binding; binding; go_process transport
tress protein (DNA damage-responsive protein 48) (DDRP 48) (YP 75) (Flocculent specific protein)
Glucose repression protein GAL83 (SPM1 protein)
Protein involved in Snf1 protein kinase complex assembly cAMP-activated protein kinase
Maintenance of Genome Stability 1 replication factor ATPase; go_function ATP binding
Eukaryotic initiation factor 4F subunit p150 (eIF4F p150) (eIF-4F p150) (mRNA cap-binding protein complex subunit p150)
go_function RNA binding; go_process protein biosynthesis
Has EST support. strongly expressed on glucose under oxygen limiting conditions
protease regulatory subunit 8 homolog (SUG1 protein) (CIM3 protein) (TAT-binding protein TBY1)
Molecular chaperone (DnaJ superfamily) DnaJ-like protein of the endoplasmic reticulum membrane
Aminopeptidase yscIII Transferrin receptor
Has EST support; similar to related proteins containing the protease-associated (PA) domain
similar to related proteins containing the protease-associated (PA) domain; go_function peptidase activity; go_process proteolysis and peptidolysis; go_function peptidase activity; go_process proteolysis and peptidolysis
alpha-ketoisocaproate reductase or hydroxyisocaproate dehydrogenase
Glyoxylate/hydroxypyruvate reductase (D-isomer-specific 2-hydroxy acid dehydrogenase superfamily); go_function oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; go_process L-serine biosynthesis
RNA splicing protein and member of the mitochondrial carrier family (MCF)
Predicted transporter (ABC superfamily); go_component membrane; go_function ATP binding; go_process transport
permease involved in the uptake of glycerophosphoinositol (GroPIns)
go_component integral to membrane; go_function transporter activity; go_process transport
serine kinase that phosphoryates SR family splicing factors
Serine Kinase that phosphoryates SR family splicing factors SRPK1-like Kinase in Yeast (SRPK1 is a human serine kinase that specifically phosphoryates arginine-serine rich domains found in the SR family of splicing factors.); go_function protein kinase activity; ATP binding; go_process protein amino acid phosphorylation
may regulate cation conductance may link integral membrane proteins to the peripheral cytoskeleton
go_function 3'-5'-exoribonuclease activity; RNA binding; go_process RNA processing
go_function acyltransferase activity; go_process metabolism
mitochondrial D-lactate ferricytochrome c oxidoreductase
sulfite reductase [NADPH] flavo protein component
DNA-binding proteins Bright/BRCAA1/RBP1 and related proteins containing BRIGHT domain
DNA helicase and DNA replication licensing factor (CDC47)
DNA replication licensing factor CDC47 (minichromosome maintenance protein) (Cell division control protein 47); go_function DNA binding; ATP binding; DNA-dependent ATPase activity; go_process DNA replication initiation
go_function membrane alanyl aminopeptidase activity; go_process proteolysis and peptidolysis
go_function asparagine synthase (glutamine-hydrolyzing) activity; go_process metabolism; asparagine biosynthesis
possible roles in filamentous growth, cell polarity, and cellular elongation
3-oxo-5-alpha-steroid 4-dehydrogenase family protein / steroid 5-alpha-reductase family protein
similar to bacterial Ada DNA-protein-cysteine methyltransferase
go_function DNA binding; methyltransferase activity; zinc ion binding; go_process DNA repair; regulation of transcription, DNA-dependent
go_component proteasome regulatory particle (sensu Eukaryota); go_process proteolysis and peptidolysis
zf-BED BED zinc finger; go_component nucleus; go_function nucleic acid binding; zinc ion binding
go_function damaged DNA binding; ATP binding; go_process mismatch repair; DNA metabolism
go_component integral to membrane; go_function molecular function unknown
go_component nucleus; go_function DNA binding; go_process regulation of transcription, DNA-dependent
transcriptional activator of amino acid biosynthetic genes
go_component membrane; go_function nucleobase transporter activity; go_process nucleobase, nucleoside, nucleotide and nucleic acid transport
Inositol-1,4,5-triphosphate 5-phosphatase
phosphatidylinositol phosphate 5-phosphatase
Alpha-isopropylmalate synthase/homocitrate synthase (LEU4)
Alpha-isopropylmalate synthase/homocitrate synthase 2-isopropylmalate synthase (Alpha-isopropylmalate synthase) (Alpha-IPM synthetase); go_function catalytic activity
go_function GTP binding; go_process protein biosynthesis
golgi uridine diphosphate-N- acetylglucosamine transporter
go_function mannose-6-phosphate isomerase activity; zinc ion binding; go_process carbohydrate metabolism
go_function electron transporter activity; go_process electron transport
Mitochondrial FAD carrier protein; go_component membrane; go_function binding; go_process transport
Mitochondrial phosphate carrier protein 2 (Phosphate transport protein 2) (PTP 2) (mPic 2) (Pi carrier isoform 2)
Fasciclin and related adhesion glycoproteins
Mannan polymerase II complex ANP1 subunit (M-Pol II subunit ANP1) (Aminonitrophenyl propanediol resistance protein)
Mannan 8 Protein of the endoplasmic reticulum with a role in retention of glycosyltransferases in the Golgi, also involved in osmotic sensitivity and resistance to aminonitrophenyl propanediol
go_component nucleus; go_function ATP binding; go_process chromosome segregation
Has EST support; essential for mitochondrial biogenesis
essential for mitochondrial biogenesis; go_function RNA binding; ribonuclease activity; go_function RNA binding; ribonuclease activity
allantoate permease Permease of the major facilitator superfamily
ribosomal protein L3 (YL1) (RP1) (Trichodermin resistance protein); go_component intracellular; ribosome; go_function structural constituent of ribosome; go_process protein biosynthesis
Has EST support. upregulated on XA; downregulated on XOL, GA, GOL; Required for rRNA processing required for essential steps leading to synthesis of 60S ribosomal subunits; present in purified ribosome assembly intermediates
Required for rRNA processing required for essential steps leading to synthesis of 60S ribosomal subunits; present in purified ribosome assembly intermediates; go_component intracellular; go_component intracellular; go_component intracellular; go_component intracellular
go_component microtubule associated complex; go_function motor activity; ATP binding
mitochondrial import inner membrane translocase subunit TIM23
go_component chromosome, pericentric region; nucleus; go_process cell cycle; mitosis
go_component membrane; integral to membrane; go_function ATP binding; go_process transport
Calcium/calmodulin-dependent protein kinase
go_function oxidoreductase activity, acting on CH-OH group of donors; go_process carbohydrate metabolism
protein involved in methionine metabolism
transcriptional regulator containing a C2H2 zinc finger; go_component nucleus; go_function nucleic acid binding; zinc ion binding; go_component nucleus; go_function nucleic acid binding; zinc ion binding
go_function serine carboxypeptidase activity; go_process proteolysis and peptidolysis
oligosaccharyltransferase epsilon subunit
RNA polymerase II fourth largest subunit
go_function DNA-directed RNA polymerase activity; go_process transcription
ATP dependent RNA helicase and U5 mRNA splicing factor
go_function GTP binding; translation elongation factor activity; go_process protein biosynthesis; translational elongation
general RNA polymerase II transcription factor
ubiquinol-cytochrome-c reductase chain VIII
go_component ubiquinol-cytochrome-c reductase complex (sensu Eukaryota); go_function ubiquinol-cytochrome-c reductase activity; go_process electron transport
arnesyl diphosphate synthetase (FPP synthetase)
May be involved in extracellular matrix assembly involved in N-linked glycosylation of cell wall mannoproteins
Glycolipid 2-alpha-mannosyltransferase (alpha-1,2-mannosyltransferase); May be involved in extracellular matrix assembly involved in N-linked glycosylation of cell wall mannoproteins; go_component membrane; go_function glycolipid 2-alpha-mannosyltransferase activity; go_process protein amino acid glycosylation; go_component membrane; go_function glycolipid 2-alpha-mannosyltransferase activity; go_process protein amino acid glycosylation
NADH-ubiquinone oxidoreductase 51 kDa subunit, mitochondrial precursor (Complex I-51KD) (CI-51KD)
transcriptional accessory protein involved in TBP (TATA-binding protein) regulation helicase MOT1
rev product adjacent to gag/pol products
hypothetical multicopy protein occurs in multiple copies through genome
Homocitrate synthase, mitochondrial precursor; go_function catalytic activity
go_function nucleic acid binding; helicase activity; ATP binding
Phosphatidylinositol-4-phosphate 5-kinase and related FYVE finger-containing proteins
cyclin-dependent serine/threonine protein kinase
Has EST support; Component of RNA polymerase II holoenzyme, involved in RNA pol II carboxy-terminal domain phosphorylation. Activity of the kinase (SSN3)/cyclin (SSN8) pair required, along with SSN6 & TUP1, for transcriptional repression of a-specific genes
cyclin-dependent serine/threonin protein kinase Component of RNA polymerase II holoenzyme, involved in RNA pol II carboxy-terminal domain phosphorylation. Activity of the kinase (SSN3)/cyclin (SSN8) pair required, along with SSN6 & TUP1, for transcriptional repression of a-specific genes (CDK8) (UME5) (PRK1); go_function protein kinase activity; ATP binding; go_process protein amino acid phosphorylation
RNA pol III initiation factor TFIIIC subunit
RNase P and RNase MRP subunit involved in RNA processing
go_function hydroxyethylthiazole kinase activity; thiamin-phosphate diphosphorylase activity; go_process thiamin biosynthesis
thiamin biosynthetic bifunctional enzyme
UDPglucose- glycoprotein glucose phosphotransferase
go_function methylenetetrahydrofolate reductase (NADPH) activity; go_process methionine metabolism
go_function racemase and epimerase activity, acting on amino acids and derivatives; go_process metabolism
clathrin assembly complex AP-3 adaptin component
fungal transcriptional regulatory protein
Has EST support; required for core glycosylation
dolichol kinase required for core glycosylation catalyzes the CTP-mediated phosphorylation of dolichol, the terminal step in dolichyl monophosphate (Dol-P) biosynthesis. required for viability, normal rates of lipid intermediate synthesis, protein N-glycosylation
chromosome condensation and segregation protein
go_function ATP binding; go_process chromosome segregation
short-chain dehydrogenase, 2,4- dienoyl-CoA reductase
Seryl-tRNA synthetase, cytoplasmic (Serine--tRNA ligase) (SerRS)
go_function tRNA ligase activity; ATP binding; serine-tRNA ligase activity; go_process tRNA aminoacylation for protein translation; seryl-tRNA aminoacylation
go_function ATP binding; ATP-dependent peptidase activity; serine-type endopeptidase activity; go_process proteolysis and peptidolysis
mitochondrial 54S ribosomal protein YmL33
similar to AAC1 and AAC3; go_component membrane; go_function binding; go_process transport; go_component membrane; go_function binding; go_process transport
Acetolactate synthase, mitochondrial precursor (Acetohydroxy-acid synthase) (ALS) (AHAS)
low affinity high capacity ammonium permease
glucoseamine-6- phosphate synthase [EC:2.6.1.16] [KO:K00820]; go_function sugar binding; go_process metabolism; carbohydrate metabolism
kinase of RNA polymerase II carboxy-terminal domain (CTD), alpha subunit
kinase of RNA polymerase II carboxy-terminal domain (CTD), alpha subunit phosphorylates the RPO21 CTD (carboxy-terminal domain) also called CTDK-I alpha subunit; go_function protein kinase activity; ATP binding; go_process protein amino acid phosphorylation
go_function signal transducer activity; go_process G-protein coupled receptor protein signaling pathway
suppressor of DNA polymerase and splicing mutations
go_component vacuole; go_function aminopeptidase I activity; go_process proteolysis and peptidolysis
go_process hypusine biosynthesis from peptidyl-lysine
NADH:ubiquinone oxidoreductase, B17.2 subunit
NADH:ubiquinone oxidoreductase, B17.2 subunit (N7BM); go_component mitochondrial inner membrane; go_function electron transporter activity; NADH dehydrogenase (ubiquinone) activity; go_process electron transport
go_component membrane; go_function transporter activity; go_process sodium ion transport
NADPH cytochrome B5 oxidoreductase-like protein
5,10-methenyltetrahydrofolate synthetase
5-formyltetrahydrofolate cyclo-ligase (5,10-methenyl-tetrahydrofolate synthetase) (Methenyl-THF synthetase) (MTHFS); go_function catalytic activity; go_process metabolism
transcriptional regulator of multiple amino acid permeases
Ssy1p controls expression of several transporter genes, including BAP2, TAT1, PTR2 and YDR046c [Saccharomyces cerevisiae]; go_component membrane; go_process transport
Dedicator of cytokinesis protein 4 CRK binding protein
regulatory subunit for the mitotic function of type I protein phosphatase
regulatory subunit for the mitotic function of type I protein phosphatase Interacts with and may be a positive regulator of GLC7 which encodes type1 protein phosphatase
go_component eukaryotic translation initiation factor 2B complex; go_function translation initiation factor activity; GTP binding; go_process translational initiation
ubiquinone/menaquinone biosynthesis methyltransferase; go_function methyltransferase activity
Pyruvate kinase (PK); go_function pyruvate kinase activity; go_process glycolysis
mitochondrial chaperonin of the DnaJ family
L-fucose permease Glucose/galactose transporter
L-fucose permease Glucose/galactose transporter (bacterial)
receptor-associated protein Yeast homolog of human BAP31 protein; go_component endoplasmic reticulum; integral to membrane; go_process intracellular protein transport; apoptosis
Has EST support; involved in cell wall biogenesis and architecture
involved in cell wall biogenesis and architecture; go_component integral to membrane; go_function molecular function unknown; go_component integral to membrane; go_function molecular function unknown
DNA polymerase delta binding protein binds to catalytic subunit of DNA polymerase alpha (Pol1p); go_component nucleus; go_function DNA binding
Aspartate-semialdehyde dehydrogenase; go_process amino acid metabolism
protein involved in processes affecting the actin cytoskeleton and mitosis
A component of the nuclear pore that is involved in the nuclear export of both mRNA and protein
epsin N-terminal homology-containing protein
go_component nucleus; go_function nucleic acid binding; zinc ion binding
Three Prime Phosphatase 1 Polynucleotide kinase 3' phosphatase
mitochondrial 37S ribosomal protein MRPS8
Uroporphyrin-III C-methyltransferase (Urogen III methylase) (SUMT) (Uroporphyrinogen III methylase) (UROM); go_function methyltransferase activity; go_process metabolism
Possibly hydroxylates ceramide-1 at C-4 to give ceramide-2. Or, hydroxylates DHS at C-4 to give PHS, which is acylated to give ceramide-2. Not yet clear whether DHS or ceramide-1 is the preferred substrate.; go_function catalytic activity; go_process metabolism
sugar transporter similar to Candida intermedia gxf1; go_component integral to membrane; go_function transporter activity; go_process transport
go_function hydrolase activity, hydrolyzing O-glycosyl compounds; go_process carbohydrate metabolism
possible hexose transporter; go_component integral to membrane; go_function transporter activity; go_process transport
Pleiotropic drug resistance proteins (PDR1-15), ABC superfamily; go_component membrane; go_function ATP binding; go_process transport