Scheffersomyces stipitis CBS 6054 chromosome 3, complete sequence.
Scheffersomyces stipitis CBS 6054 (Pichia stipitis CBS 6054)
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
Genome sequence of the lignocellulose-bioconverting and xylose-fermenting yeast Pichia stipitis
Submitted (05-JUN-2017) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (12-DEC-2006) US DOE Joint Genome Institute, 2800 Mitchell Drive B100, Walnut Creek, CA 94598-1698, USA
PROVISIONAL REFSEQ: This record has not yet been subject to final\nNCBI review. The reference sequence is identical to CP000497.\nURL -- http://www.jgi.doe.gov/pichia\nJGI Project ID: 3634480\nSource DNA was provided by Jose Laplaza and Thomas Jeffries\n(twjeffri@wisc.edu)\nStock culture is available from Cletus P Kurtzman\n(kurtsman@ncaur.usda.gov)\nContacts: Thomas Jeffries (twjeffri@wisc.edu)\n Paul Richardson (microbes@cuba.jgi-psf.org)\nAnnotation done by JGI-PGF\nManual curation done by the P. stipitis User Community\nFinishing done by JGI-Stanford Human Genome Center\n(www-shgc.stanford.edu)\nUnresolved repeat 15497-16547\nUnresolved repeat 1259800-1261020\nUnresolved repeat 1704790-1706210\nThe finished chromosome has no gaps. The sequence has less than one\nerror in 100,000 bp.\nThe JGI and collaborators endorse the principles for the\ndistribution and use of large scale sequencing data adopted by the\nlarger genome sequencing community and urge users of this data to\nfollow them. It is our intention to publish the work of this\nproject in a timely fashion and we welcome collaborative\ninteraction on the project and analysis.\n(http://www.genome.gov/page.cfm?pageID=10506376).\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: INSDC submitter\nAnnotation Status :: Full annotation\nAnnotation Pipeline :: Eukaryotic Annotation Propagation Pipeline\n##Genome-Annotation-Data-END##\nCOMPLETENESS: full length.
go_component nucleus; go_function DNA binding; zinc ion binding; go_process transcription
Cyclohexanone monooxygenase steroid monooxygenase (CPM1) (Bacterial)
C2H2 zinc finger protein Ribonuc_L-PSP Endoribonuclease L-PSP
similar to MIG2 and NRG1 transcription factor involved in glucose repression Ribonuc_L-PSP Endoribonuclease L-PSP; go_component nucleus; go_function nucleic acid binding; zinc ion binding
go_function alanine racemase activity; pyridoxal phosphate binding
Dihydrodipicolinate synthase (DHDPS) putative; go_function dihydrodipicolinate synthase activity
Protein localizes to actin cortical patches. Probable binding site on actin lies on front surface of subdomain 3 and 4.; go_function actin binding; go_process actin filament depolymerization
Mitochondrial protein of unknown function
go_component actin cytoskeleton; go_function structural constituent of cytoskeleton
go_function alpha-amylase activity; hydrolase activity, hydrolyzing O-glycosyl compounds; go_process carbohydrate metabolism
go_function DNA binding; ATP-dependent DNA helicase activity; go_process double-strand break repair via nonhomologous end-joining
go_component ribonucleoprotein complex; go_process rRNA processing
positive regulator of meiosis, MAPK related ser/thr protein kinase
positive regulator of meiosis, MAPK related ser/thr protein kinase dispensable for mitosis, stimulates early, middle and late gene expression and negatively regulates IME1; go_function protein kinase activity; ATP binding; go_process protein amino acid phosphorylation
high affinity nicotinic acid plasma membrane permease
Zinc-binding oxidoreductase alcohol dehydrogenase
Putative NADPH:quinonereductase/dehydrogenase alcohol dehydrogenase; go_function alcohol dehydrogenase activity, zinc-dependent
go_function alcohol dehydrogenase activity, zinc-dependent; zinc ion binding
go_component nucleus; go_function nucleic acid binding; zinc ion binding
Required for processing of pre-tRNAs and the 5.8S rRNA precursor
go_component cytoplasm; go_function tRNA ligase activity; ATP binding; nucleic acid binding; go_process tRNA aminoacylation for protein translation
go_function glutamate-tRNA ligase activity; ATP binding; go_process glutamyl-tRNA aminoacylation
structural maintenance of chromosomes protein
Structural maintenance of chromosome 5 (DNA repair protein spr18) (SMC partner of rad18); go_component nucleus; go_function ATP binding; go_process chromosome segregation
G4 quadruplex nucleic acid binding protein
associated with tRNA and amino acyl-tRNA synthetases GU4 nucleic-binding protein 1 (G4p1 protein) (P42) (ARC1 protein); go_function tRNA binding
transcriptional regulator Regulator of drug sensitivity (RDS2)
transcriptional regulator (RDS2) possibly involved in heme regulation heme binding site; go_component nucleus; go_function transcription factor activity; zinc ion binding; go_process regulation of transcription, DNA-dependent
Probable metabolite transport protein; go_component integral to membrane; go_function transporter activity; go_process transport
60S ribosomal protein L28 (L27A) (L29) (YL24) (RP62); go_component intracellular; ribosome; go_function structural constituent of ribosome; go_process protein biosynthesis
first step in riboflavin biosynthesis; go_function GTP cyclohydrolase II activity; go_process riboflavin biosynthesis; go_function GTP cyclohydrolase II activity; go_process riboflavin biosynthesis
fungal Zn(2)-Cys(6) binuclear cluster zinc finger transcription factor; go_component nucleus; go_function transcription factor activity; zinc ion binding; DNA binding; go_process regulation of transcription, DNA-dependent; transcription
related to RNA processing and transport; go_function 3'-5'-exoribonuclease activity; RNA binding; go_process RNA processing; go_function 3'-5'-exoribonuclease activity; RNA binding; go_process RNA processing
phosphatidyl- ethanolamine N-methyltransferase
go_function nucleic acid binding; helicase activity; ATP binding
Phosphoglucomutase 2 (Glucose phosphomutase 2) (PGM 1) (PGMU); go_function intramolecular transferase activity, phosphotransferases; go_process carbohydrate metabolism
zinc finger Dal80-like transcriptional repressor
go_component nucleus; go_function transcription factor activity; go_process regulation of transcription, DNA-dependent
go_function GTP binding; go_process small GTPase mediated signal transduction
Gtp-binding protein of the rho subfamily of ras-like proteins; go_function GTP binding; go_process small GTPase mediated signal transduction
go_component clathrin coat of trans-Golgi network vesicle; go_process protein complex assembly; intracellular protein transport
clathrin associated protein complex large subunit, gamma-adaptin
82-kDa subunit of RNA polymerase III (C); go_function DNA binding; DNA-directed RNA polymerase activity; go_process transcription
Aquaporin (major intrinsic protein family); go_component membrane; go_function transporter activity; go_process transport
integral membrane ornithine transporter of mitochondria
Mitochondrial integral membrane protein, ornithine transporter (Yong-Su Jin[2006-01-06 12:10:29]); go_component membrane; go_function binding; go_process transport
with sequence similarity to human XPBC; go_function nucleic acid binding; helicase activity; ATP binding; type III site-specific deoxyribonuclease activity; go_process DNA restriction-modification system
nonribosomal protein of the nucleolus and coiled bodies
pantoate-beta- alanine ligase, pantothenic acid biosynthesis; go_function pantoate-beta-alanine ligase activity; go_process pantothenate biosynthesis
HMG-domain site-specific DNA binding protein and regulator of filamentious growth; go_function DNA binding; go_process regulation of transcription, DNA-dependent; go_function DNA binding; go_process regulation of transcription, DNA-dependent
go_component integral to membrane; go_function transporter activity; go_process transport
Glycoside hydrolase family 2 (Mannanase, beta-galactosidase)
Glycoside hydrolase family 2, Beta-mannosidase precursor (Mannanase); beta-Galactosidase /glucuronidase domain; Galactose-binding domain; go_function hydrolase activity, hydrolyzing O-glycosyl compounds; go_process carbohydrate metabolism; go_function hydrolase activity, hydrolyzing O-glycosyl compounds; go_process carbohydrate metabolism
part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA)
Rrp9p is an ortholog of the Homo sapiens U3-55k protein the Homo sapiens cDNA partially complements a yeast rrp9 null mutant
DNA-directed RNA polymerase III subunit, HMG-like
go_function carbonate dehydratase activity; zinc ion binding; go_process carbon utilization
UDP-glucose:dolichyl-phosphate glucosyltransferase
go_component nucleus; go_function polynucleotide 5'-phosphatase activity; go_process mRNA capping
Isocitrate dehydrogenase [NADP] peroxisomal (Oxalosuccinate decarboxylase) (IDH) (PS-NADP-IDH) (CtIDP2)
go_function oxidoreductase activity; go_process metabolism
involved in intracellular iron metabolism
voltage-gated protein/chloride channel involved in intracellular iron metabolism (CLCN); go_component membrane; go_function voltage-gated chloride channel activity; go_process chloride transport; go_component membrane; go_function voltage-gated chloride channel activity; go_process chloride transport
go_function methyltransferase activity; go_component nucleus; go_process nucleobase, nucleoside, nucleotide and nucleic acid metabolism
ATP-binding cassette transporter family member
go_component membrane; integral to membrane; go_function ATP binding; go_process transport
Sterol 3-beta-glucosyltransferase (Autophagy-related protein 26) (UDP-glycosyltransferase 51)
go_function transferase activity, transferring hexosyl groups; go_process carbohydrate metabolism; lipid glycosylation
Homoserine O-acetyltransferase (Homoserine O-trans-acetylase)
involved in cell wall biogenesis and architecture
Extra Cellular Matrix involved in cell wall biogenesis and architecture Glutathione transferase
go_function nucleic acid binding; helicase activity; ATP binding; type III site-specific deoxyribonuclease activity; go_process DNA restriction-modification system
go_component nucleus; go_function nucleic acid binding; zinc ion binding; go_component nucleus; go_function nucleic acid binding; zinc ion binding
DNA replication licensing factor, MCM6 component
go_function DNA binding; ATP binding; DNA-dependent ATPase activity; go_process DNA replication initiation
go_component nucleus; go_function transcription factor activity; zinc ion binding; DNA binding; go_process regulation of transcription, DNA-dependent; transcription
go_function protein kinase activity; ATP binding; go_process protein amino acid phosphorylation
go_function DNA binding; zinc ion binding
positive regulator of cytochrome C genes CYC1 and CYC7
go_function DNA binding; transcription factor activity; go_process transcription; regulation of transcription, DNA-dependent
go_component membrane; go_function amino acid-polyamine transporter activity; go_process amino acid transport
Fungal transcriptional regulatory protein
go_component nucleus; go_function transcription factor activity; zinc ion binding; go_process regulation of transcription, DNA-dependent
go_component nucleus; small nucleolar ribonucleoprotein complex
converts oxidized glutathine and NADPH into two glutathiones and NADP+; go_component cytoplasm; go_function disulfide oxidoreductase activity; oxidoreductase activity; go_process electron transport
go_component intracellular; ribosome; go_function structural constituent of ribosome; go_process protein biosynthesis
go_function electron transporter activity; go_process electron transport
inorganic phosphate transporter, transmembrane protein
Pleiotropic drug resistance proteins (PDR1-15), ABC superfamily; go_component membrane; go_function ATP binding; go_process transport
Cytochrome P450 52A6 (CYPLIIA6) (Alkane-inducible P450-ALK3)
Cytochrome P450 52A12 (Alkane hydroxylase 1) (Alkane-inducible p450alk 1) (DH-ALK2); go_process electron transport
Galactokinase (Galactose kinase); go_function ATP binding; kinase activity; go_process phosphorylation
GAL10 bifunctional protein [Includes: UDP-glucose 4-epimerase (Galactowaldenase) Aldose 1-epimerase (Mutarotase)]; go_function aldose 1-epimerase activity; catalytic activity; go_process galactose metabolism; nucleotide-sugar metabolism
go_component Golgi cis-face; go_process ER to Golgi transport
UDP-glucose 4-epimerase; go_function catalytic activity; go_process nucleotide-sugar metabolism
galactose-1-phosphate uridyl transferase
go_function UTP-hexose-1-phosphate uridylyltransferase activity; go_process galactose metabolism
go_component cytoplasm; go_process autophagy
go_function GTP binding; go_process cell cycle
Has EST support; involved in nuclear import
protein involved in nuclear import required for the docking of import substrate to the nuclear membrane/pore identified as an rna1-1 synthetic lethal; go_function protein transporter activity; go_component nucleus; nuclear pore; cytoplasm; go_process protein-nucleus import, docking; go_function protein transporter activity; go_component nucleus; nuclear pore; cytoplasm; go_process protein-nucleus import, docking
Zn finger-containing GTPase- Activating Protein for ARF
go_component nucleus; go_function DNA binding
Protein predicted to be involved in carbohydrate metabolism
prefoldin subunit 1, component of a chaperone
go_function catalytic activity; ATP binding; go_process metabolism; fructose 2,6-bisphosphate metabolism
alpha-1,6-mannosyltransferase MNN11 (Mannan polymerase II complex MNN11 subunit) (M-Pol II subunit MNN11); go_function transferase activity, transferring hexosyl groups; go_component integral to membrane
1,3-beta-D-glucan synthase subunit (BGS3) (GSC2)
1,3-beta-D-glucan synthase subunit Highly similar to FKS1 (GSC1). GSC2 and FKS1 encode redundant catalytic components of 1,3-beta-glucan synthase. Deletion of both is lethal; go_function 1,3-beta-glucan synthase activity; go_component 1,3-beta-glucan synthase complex; membrane; go_process beta-1,3 glucan biosynthesis
similar to members of the QM gene family, which is implicated in differentiation in other eukaryotes and tumorigenesis in humans homology to rat L10 ubiquinol-cytochrome C reductase complex subunit VI requiring protein; go_component intracellular; ribosome; go_function structural constituent of ribosome; go_process protein biosynthesis
involved in synthesis of GDP-mannose and dolichol-phosphate-mannose required for protein assembly in endoplasmic reticulum; go_component cytoplasm; go_function phosphomannomutase activity; go_process mannose biosynthesis
go_component membrane; go_function ATP binding; go_process transport
go_component integral to membrane; go_process intracellular protein transport
cell wall glucanase Probable family 17 glucosidase SCW4 precursor (Soluble cell wall protein 4)
go_component chromatin silencing complex; go_function DNA binding; go_process chromatin silencing; regulation of transcription, DNA-dependent
HTX1 Zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila); go_component nucleus; go_function nucleic acid binding; zinc ion binding
Phenylalanyl-tRNA synthetase, beta subunit, cytoplasmic
go_function phenylalanine-tRNA ligase activity; ATP binding; go_process phenylalanyl-tRNA aminoacylation
go_component mitochondrial outer membrane translocase complex; go_process protein targeting; intracellular protein transport
go_function homoserine dehydrogenase activity; go_process amino acid biosynthesis
go_process intracellular signaling cascade
go_component membrane; go_process transport
Proline-specific permease (Proline transport protein)
go_component microtubule associated complex; go_function motor activity; ATP binding
transcriptional regulator of peptide transport
Regulator of expression of the PTR2, GAP1, and BAP2 genes involved in the the control of peptide transport [Saccharomyces cerevisiae]
go_function lyase activity; go_process amino acid metabolism
go_function DNA binding; transcription factor activity; go_process RNA elongation; regulation of transcription, DNA-dependent; transcription
transcription elongation factor S-IIMeiotic DNA recombination factor (STP-alpha)
go_function ubiquitin conjugating enzyme activity; go_process protein modification; ubiquitin cycle
Glutamyl-tRNA(Gln) amidotransferase subunit A (Glu-ADT subunit A)
Glutamyl-tRNA(Gln) amidotransferase subunit A (Glu-ADT subunit A) (GATA) (bacterial); go_function amidase activity
succinate-semialdehyde dehydrogenase NADP+ dependent
succinate-semialdehyde dehydrogenase similar to NADP-dependent glyceraldehyde-3-phosphate dehydrogenase (GAPN); go_function oxidoreductase activity; go_process metabolism
go_function DNA binding; transcription factor activity; go_process regulation of transcription, DNA-dependent
Adenosylmethionine--8-amino-7-oxononanoate aminotransferase.; go_function transaminase activity
member of major facilitator superfamily multidrug-resistance protein
Protein necessary for structural stability of L-A double-stranded RNA-containing particles
go_function oxidoreductase activity; go_process electron transport
mitochondrial 54S ribosomal protein YmL27
DNA-directed DNA polymerase epsilon, subunit C
DNA polymerase V that has motifs typical of DNA polymerase family
Aphidicolin-sensitive stimulated by yeast proliferating cell nuclear antigen (PCNA).; go_function DNA binding; DNA-directed DNA polymerase activity; go_process transcription
ATP-binding transporter, 3- prime end; go_component membrane; integral to membrane; go_function ATP binding; go_process transport
dipeptidyl-peptidase III (DPP III) (Dipeptidyl aminopeptidase III) (Dipeptidyl arylamidase III)
go_function dipeptidyl-peptidase III activity; go_component cytoplasm; go_process proteolysis and peptidolysis
5'-AMP-activated protein kinase, gamma subunit
nuclear protein involved in release from glucose repression, invertase expression, and sporulation
nuclear pore protein Interacts with nuclear pore complex and participates in nucleocytoplasmic transport required for poly(A)+ RNA export
go_function hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; go_process carbohydrate metabolism
12-oxophytodienoate reductase 1 (12-oxophytodienoate-10,11-reductase 1) (OPDA-reductase 1) (AtOPR1) (FS-AT-I) (OYE)
go_component membrane; go_function nucleobase transporter activity; go_process nucleobase, nucleoside, nucleotide and nucleic acid transport
Glutamyl-tRNA(Gln) amidotransferase subunit A (amidase)
Glutamyl-tRNA(Gln) amidotransferase subunit A (amidase) (AMID1) (bacterial); go_function amidase activity
go_function tRNA ligase activity; ATP binding; go_process tRNA aminoacylation for protein translation
conserved hypothetical protein; go_function DNA binding; go_process regulation of transcription, DNA-dependent
vacuolar protein sorting associated protein
Protein of the Sec1p family essential for vacuolar protein sorting required for the function of both Pep12p and the early endosome/late Golgi SNARE Tlg2p; go_function protein transporter activity; go_process protein secretion
go_function metalloendopeptidase activity; go_process proteolysis and peptidolysis
Transcription factor RBF1 (RPG-box-binding factor) (Repressor-activator protein 1)
Alanyl-tRNA synthetase, cytoplasmic (Alanine--tRNA ligase) (AlaRS)
go_function alanine-tRNA ligase activity; ATP binding; nucleic acid binding; go_process alanyl-tRNA aminoacylation
3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes
go_process Mo-molybdopterin cofactor biosynthesis
ATP dependent transporter multidrug resistance (SNQ2)
Spliced mRNA and Cell cycle regulated gene
go_function glycine hydroxymethyltransferase activity; go_process glycine metabolism; L-serine metabolism
strongly conserved; no transcript evident
sugar transporter strongly conserved; go_component integral to membrane; go_function transporter activity; go_process transport
hemolysin III domain membrane protein; go_component integral to membrane
go_function transcriptional repressor activity; go_component nucleus; go_process negative regulation of transcription
go_component membrane; go_function molecular function unknown
go_function protein transporter activity; go_component intracellular; nucleus; go_process protein-nucleus import
go_component mitochondrion; go_function cytochrome-c oxidase activity; go_process electron transport
go_function transaminase activity; go_process metabolism
transporter of the inner mitochondrial membrane oriented with a probable ATP-binding site in the matrix, so that it could function to export substrates from the matrix to the cytoplasm; go_component membrane; integral to membrane; go_function ATP binding; go_process transport
go_function membrane alanyl aminopeptidase activity; go_process proteolysis and peptidolysis
cysteine synthase (O-acetylserine sulfhydrylase) (O-acetylserine (Thiol)-lyase) (CSase)
cysteine synthase (O-acetylserine sulfhydrylase) (O-acetylserine (Thiol)-lyase) (CSase) (CYSK2); go_function lyase activity; go_process amino acid metabolism
beta-1,6-N-acetylglucosaminyltransferase, contains WSC domain
cutinase transcription factor 1 alpha potential fungal Zn(2)-Cys(6) binuclear cluster domain; go_component nucleus; go_function transcription factor activity; zinc ion binding; DNA binding; go_process regulation of transcription, DNA-dependent; transcription
go_function catalytic activity; nutrient reservoir activity
go_function catalytic activity; go_process metabolism
nucleotide excision repair protein (ubiquitin-like protein)
May function to facilitate or stabilize the interaction between U1 snRNP and the 5' splice site in pre-mRNAs
mitochondrial 54S ribosomal protein YmL31
mucin-like protein with chitinase features
Has EST support; possibly part of mannoprotein possibly involved in adhesion
serine rich protein with possible protein kinase and chitinase domains probable cell wall protein mucin-like; possibly part of mannoprotein possibly involved in adhesion
succinate dehydrogenase (ubiquinone) cytochrome b subunit precursor (SDH3); go_component membrane; go_function succinate dehydrogenase activity; go_process tricarboxylic acid cycle; electron transport
Has EST support; possibly involved in Phosphatidylinositol 3-phosphate binding
possibly involved in Phosphatidylinositol 3-phosphate binding; go_function zinc ion binding; go_function zinc ion binding
go_component membrane; go_function oligosaccharyl transferase activity; go_process protein amino acid glycosylation
activator of IME1 Predicted N6-adenine RNA methylase IME4
appears to activate IME1 in response to cell-type and nutritional signals and thereby regulate meiosis
appears to activate IME1 in response to cell-type and nutritional signals and thereby regulate meiosis; go_function methyltransferase activity; go_component nucleus; go_process nucleobase, nucleoside, nucleotide and nucleic acid metabolism; go_function methyltransferase activity; go_component nucleus; go_process nucleobase, nucleoside, nucleotide and nucleic acid metabolism
SH3 domain protein involved in assembly of cortical actin cytoskeleton
go_function protein dimerization activity
Glyoxylate/hydroxypyruvate reductase (D-isomer-specific 2-hydroxy acid dehydrogenase superfamily); go_function oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; go_process L-serine biosynthesis
Cytochrome c oxidase polypeptide IV, mitochondrial precursor
go_component mitochondrial membrane; go_function cytochrome-c oxidase activity; go_process electron transport
Protein phosphatase PP2A regulatory subunit B (PR55) (Cell division control protein 55)
regulator of cell wall mannosyl phosphorylation
methylisocitrate lyase (2-methylisocitrate lyase)
zinc finger transcription factor; go_component nucleus; go_function transcription factor activity; zinc ion binding; go_process regulation of transcription, DNA-dependent
3-isopropylmalate dehydratase (aconitase superfamily)
3-isopropylmalate dehydratase large subunit (Isopropylmalate isomerase) (Alpha-IPM isomerase) (IPMI) (bacterial); go_function lyase activity; hydro-lyase activity; go_process metabolism
Removes amide group from N-terminal asparagine and glutamine, to generate aspartate and glutamate; go_function hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; go_process nitrogen compound metabolism
go_component membrane; go_function transporter activity; go_process transport
involved in mannose metabolism and cell wall synthesis
Fungal specific transcription factor; go_component nucleus; go_function transcription factor activity; zinc ion binding; DNA binding; go_process regulation of transcription, DNA-dependent; transcription
basic helix-loop-helix transcription factor
go_component intracellular; ribosome; go_function structural constituent of ribosome; RNA binding; go_process protein biosynthesis
Ca2+/calmodulin-dependent protein kinase
glucosamine-phosphate N-acetyltransferase
go_function N-acetyltransferase activity
Glycosyl hydrolase, family 47 alpha mannosidase; go_component membrane; go_function mannosyl-oligosaccharide 1,2-alpha-mannosidase activity; calcium ion binding; go_process N-linked glycosylation
go_function protein kinase activity; ATP binding; protein serine/threonine kinase activity; go_process protein amino acid phosphorylation
mitochondrial 54S ribosomal protein YmL24/YmL14
Homoserine O-acetyltransferase (Homoserine O-trans-acetylase) (Homoserine transacetylase) (HTA)
copper-transporting P1-type ATPase (CRD1); go_component membrane; go_function ATP binding; hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; metal ion binding; catalytic activity; go_process metal ion transport; metabolism
NADH:flavin oxidoreductase/12-oxophytodienoate reductase
NADH:flavin oxidoreductase/12-oxophytodienoate reductase NADPH dehydrogenase (OYE32); go_function oxidoreductase activity; go_process electron transport
pyruvate decarboxylase regulator, putative; go_component nucleus; go_function nucleic acid binding
Cytochrome P450 52A13 (Alkane hydroxylase 2) (Alkane-inducible p450alk 2) (DH-ALK2)
required for S-phase initiation or completion (MCM10)
Protein required for S-phase (DNA synthesis) initiation or completion
go_component cytoplasm; go_function shikimate 5-dehydrogenase activity; go_process aromatic amino acid family biosynthesis, shikimate pathway
MFS family transporter multidrug-resistance type transporter
MFS family transporter multidrug-resistance type transporter (MFS1)
go_function hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; go_process nitrogen compound metabolism
Alternative oxidase, mitochondrial precursor (SHAM-sensitive terminal oxidase) (STO1)
Alternative oxidase, mitochondrial precursor (SHAM-sensitive terminal oxidase) (AOX1); go_component mitochondrial membrane; go_process respiratory gaseous exchange
similar to heat shock transcription factor possible implication in 5' binding to FAS2 site AGAAN (HSTF); go_component nucleus; go_function transcription factor activity; go_process regulation of transcription, DNA-dependent
zinc finger transcription factor of the LYS14 family
Dihydroxyacetone kinase (Glycerone kinase) (DHA kinase); go_function glycerone kinase activity; go_process glycerol metabolism
component of the ARGR regulatory complex
regulates arginine-responsive genes; go_component nucleus; go_function transcription factor activity; zinc ion binding; go_process regulation of transcription, DNA-dependent; go_component nucleus; go_function transcription factor activity; zinc ion binding; go_process regulation of transcription, DNA-dependent
cell wall mannoprotein contains chitinase family signature
go_component intracellular; go_function cysteine-type endopeptidase activity; ubiquitin thiolesterase activity; exonuclease activity; go_process ubiquitin-dependent protein catabolism
protein required for protein disulfide bond formation in the ER
ERO1; essential, FAD-dependent oxidase of protein disulfide isomerase
ATP-dependent RNA helicase CA3 of the DEAD/DEAH box family
SED5-binding protein 2 (SEC24-related protein 2) component of COPII coat of ER- Golgi vesicles
component of COPII coat of ER- Golgi vesicles The Sec23p-Sec24p complex is one of three cytoplamic COPII factors involved in ER to Golgi transport; go_component COPII vesicle coat; go_function protein binding; go_process intracellular protein transport
tyrosine-protein phosphatase (PTPX); go_function protein tyrosine/serine/threonine phosphatase activity; go_process protein amino acid dephosphorylation
GATA type transcriptional activator of nitrogen-regulated genes
Mitochondrial carnitine-acylcarnitine carrier protein; go_component membrane; go_function binding; go_process transport
mitochondrial complex I NUIM TYKY subunit (proton translocation)
go_function electron transporter activity; iron ion binding; go_process electron transport
go_function cytochrome-c oxidase activity; go_process electron transport
Glucoamylase 1 precursor (Glucan 1,4-alpha-glucosidase) (1,4-alpha-D-glucan glucohydrolase)
go_function hydrolase activity, hydrolyzing O-glycosyl compounds; go_process carbohydrate metabolism
Muscle M-line assembly protein unc-89 (Uncoordinated protein 89)
similar to Muscle M-line assembly protein unc-89 (Uncoordinated protein 89)
go_function protein binding; go_process apoptosis
leukotriene A-4 hydrolase (LTA-4 hydrolase) (Leukotriene A(4) hydrolase)
mitochondrial 37S ribosomal protein MRPS5
membrane transporter of the MFS-MDR family (DHA12) (TPO3); go_component integral to membrane; go_function transporter activity; go_process transport
Predicted transporter ADD1 (major facilitator superfamily)
glycosylphosphatidylinositol synthesis N-acetylglucosaminyltransferase complex, subunit PIG-Q/GPI1
Has EST support; required for phosphatidylinositol biosynthesis Cell wall/membrane/envelope biogenesis
glycosylphosphatidylinositol synthesis Participates in synthesis of N-acetylglucoaminylphosphatidylinositol, the first intermediate in synthesis of glycosylphosphatidylinositol (GPI) anchors; required for phosphatidylinositol biosynthesis Cell wall/membrane/envelope biogenesis; go_function phosphatidylinositol N-acetylglucosaminyltransferase activity; go_component integral to membrane; go_process GPI anchor biosynthesis; go_function phosphatidylinositol N-acetylglucosaminyltransferase activity; go_component integral to membrane; go_process GPI anchor biosynthesis
40S ribosomal protein S0-A (Nucleic acid-binding protein NAB1A); go_component intracellular; ribosome; go_function structural constituent of ribosome; go_process protein biosynthesis
protein involved in (1,3)-beta-glucan synthesis
Beta-hexosaminidase A precursor (N-acetyl-beta-glucosaminidase) (Beta-N-acetylhexosaminidase) (Chitobiase); go_function hydrolase activity, hydrolyzing O-glycosyl compounds; go_process carbohydrate metabolism
glycosyl hyrolase, family 3-like protein
ATP synthase f chain, mitochondrial precursor
[Hydroxymethylglutaryl-CoA reductase(NADPH)] kinase KIN2
Has EST support. Upregulated 3 to 5 fold on GOL relative to XA and XOL
[Hydroxymethylglutaryl-CoA reductase(NADPH)] kinase upregulated 3 to 5 fold on GOL; go_function protein kinase activity; ATP binding; protein serine/threonine kinase activity; go_process protein amino acid phosphorylation
chitin deacetylase Required for proper formation of the ascospore wall; go_function hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; go_process carbohydrate metabolism
go_component nucleus; go_function DNA binding; go_process nucleosome assembly
putative inorganic phosphate transporter
Lysophospholipase (Phospholipase B); go_function phospholipase activity; go_process phospholipid catabolism
ATP-dependent RNA helicase Required for maturation of the 35S primary transcript of pre-rRNA and is required for cleavages leading to mature 18S RNA; go_function nucleic acid binding; helicase activity; ATP binding
DNA-directed RNA polymerase II holoenzyme and kornberg s mediator
go_component membrane; go_function mannosyltransferase activity; go_process O-linked glycosylation
dolichyl-phosphate-mannose-protein mannosyltransferase
pyrimidine precursor biosynthesis enzyme
Putative cytochrome C oxidase assembly protein
go_function nucleic acid binding; nuclease activity
staphylococcal nuclease domain-containing protein 1
go_component proteasome core complex (sensu Eukaryota); go_function endopeptidase activity; go_process ubiquitin-dependent protein catabolism
D-arabinono-1,4-lactone oxidase (ALO) (L-galactono-gamma-lactone oxidase)
go_component membrane; go_function D-arabinono-1,4-lactone oxidase activity; go_process electron transport; go_component membrane; go_function D-arabinono-1,4-lactone oxidase activity; go_process electron transport
go_function hydroxymethylglutaryl-CoA synthase activity; go_process acetyl-CoA metabolism
go_function RNA binding; RNA methyltransferase activity; go_process RNA processing
go_function 3'-5'-exoribonuclease activity; RNA binding; go_process RNA processing
protein farnesyltransferase, beta subunit
Protein farnesyltransferase beta subunit (CAAX farnesyltransferase beta subunit) (RAS proteins prenyltransferase beta) (FTase-beta); go_function catalytic activity
go_component exocyst; go_process vesicle docking during exocytosis
Cytochrome oxidase assembly factor COX11
Posttranslational modification, protein turnover, chaperones
cytochrome-c oxidase assembly protein; Mitochondrial membrane protein required for insertion of Cu(B) and magnesium during assembly of cytochrome c oxidase; Posttranslational modification, protein turnover, chaperones; go_function copper ion binding; go_function copper ion binding
ferric reductase transmembrane component (6 domains)(Ferric-chelate reductase)
Ferric reductase, NADH/NADPH oxidase transmembrane component (FRE10) (FRE2) (FRE11) (FRE1); go_function oxidoreductase activity; go_component membrane; go_process electron transport
conserved hypothetical protein of the cinnamyl-alcohol dehydrogenase family
go_function O-sialoglycoprotein endopeptidase activity; go_process proteolysis and peptidolysis
go_component ribosome; go_function structural constituent of ribosome; go_process protein biosynthesis
go_function protein tyrosine/serine/threonine phosphatase activity; go_process protein amino acid dephosphorylation
go_component endoplasmic reticulum; go_function molecular function unknown
tRNA (guanine-N(7)-)-methyltransferase (tRNA(m7G46)-methyltransferase)
mitochondrial 54S ribosomal protein YmL11
go_component intracellular; go_function double-stranded RNA binding; RNA binding; ribonuclease III activity; go_process RNA processing
go_function lyase activity; hydro-lyase activity; go_process metabolism
Anion Exchange Family protein Na+-independent Cl/HCO3 exchanger AE1 and related transporters (SLC4 family)
phosphodiesterase; putative nucleotide pyrophosphatase precursor
phosphodiesterase; Ectonucleotide pyrophosphatase/phosphodiesterase 3; go_function hydrolase activity; go_process nucleotide metabolism
go_function oxidoreductase activity; go_process amino acid metabolism
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating
go_function 3-beta-hydroxy-delta5-steroid dehydrogenase activity; go_process steroid biosynthesis
go_function DNA binding; transcription factor activity; go_process regulation of transcription
translation elongation factor eEF1beta; go_component eukaryotic translation elongation factor 1 complex; go_function translation elongation factor activity; go_process translational elongation
Nucleic acid binding, Zn finger Tps5.4; go_function nucleic acid binding
hypothetical protein MRS512-like protein
go_function chitin synthase activity; go_process chitin biosynthesis
Regulator of chromosome condensation (PRP20 protein) (Pheromone response pathway component SRM1); go_component nucleus; go_function DNA binding; go_process cell cycle; mitosis
CCR4 Associated Factor 40 kDa; go_component CCR4-NOT complex; go_process regulation of transcription from RNA polymerase II promoter; sex differentiation
Multi antimicrobial extrusion protein; go_component membrane; go_function drug transporter activity; antiporter activity; go_process multidrug transport
bystin-family protein putative nuclear protein
has effects on N-glycosylation of proteins in the secretory pathway
Essential Nuclear Protein bystin-family protein putative nuclear protein with effects on N-glycosylation of proteins in the secretory pathway by similarity to yeast end1
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase 1 (Phosphoinositide phospholipase C) (PLC-1) (Phospholipase C-1)
go_function phosphoinositide phospholipase C activity; phospholipase C activity; go_process lipid metabolism; signal transduction; intracellular signaling cascade
go_function catalytic activity; go_process histidine biosynthesis
yeast chromatin modifying complex protein
Yeast homolog of the human leukemogenic protein AF9; member of a yeast chromatin modifying complex; go_component nucleus; go_process regulation of transcription, DNA-dependent
Inositol-1,4,5-triphosphate 5-phosphatase
Nuclear-encoded mitochondrial protein involved in transport of flavine into mitochondria; go_component membrane; go_function binding; go_process transport
go_function RNA binding; ribonuclease H activity
dihydrolipoamide acetyltransferase component
go_function acyltransferase activity; protein binding; go_process metabolism
putative transcription initiation factor
Transcription factor for RNA polymerase III; go_function catalytic activity; go_process metabolism
go_component COPII vesicle coat; go_function protein binding; go_process intracellular protein transport
Lysyl-tRNA synthetase, mitochondrial precursor (Lysine--tRNA ligase) (LysRS); go_component cytoplasm; go_function tRNA ligase activity; ATP binding; nucleic acid binding; go_process tRNA aminoacylation for protein translation
probable hexose transporter; go_component integral to membrane; go_function transporter activity; go_process transport
hypothetical conserved protein of unknown function
GTPase activating protein BEM2/IPL2 (Bud emergence protein 2); go_function guanyl-nucleotide exchange factor activity; go_process intracellular signaling cascade
Protein involved in recombination repair
similar to Saccharomyces pombe rad18; Structural maintenance of chromosomes (SMC) protein
go_component nucleus; go_function ATP binding; go_process chromosome segregation
go_component membrane; go_process signal transduction
go_component intracellular; go_function exonuclease activity
go_function protein kinase activity; ATP binding; two-component response regulator activity; DNA binding; go_process protein amino acid phosphorylation; two-component signal transduction system (phosphorelay); regulation of transcription, DNA-dependent
zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type; go_component nucleus; go_function transcription factor activity; zinc ion binding; go_process regulation of transcription, DNA-dependent
Salicylate hydroxylase (Salicylate 1-monooxygenase)
Salicylate hydroxylase (Salicylate 1-monooxygenase) (bacterial); go_function monooxygenase activity; go_process aromatic compound metabolism
putative mitochondrial 37S ribosomal protein SWS2
go_component intracellular; ribosome; go_function RNA binding; structural constituent of ribosome; go_process protein biosynthesis
go_function glutathione synthase activity; ATP binding; go_process glutathione biosynthesis
go_component intracellular; ribosome; go_function structural constituent of ribosome; go_process translational elongation
SNF2 family DNA-dependent ATPase helicase of the Snf2/Rad54 family Shows homology to SNF2 transcriptional regulator; go_function DNA binding; ATP binding; nucleic acid binding; helicase activity
flavohemoglobin (bacterial); go_function oxidoreductase activity; go_process oxygen transport; electron transport
mitochondrial 37S ribosomal protein RSM19
ATP-dependent RNA helicase DBP6 (DEAD-box protein 6)
RNA helicase required for 60S ribosomal subunit assembly; go_function nucleic acid binding; helicase activity; ATP binding; type III site-specific deoxyribonuclease activity; go_process DNA restriction-modification system
involved in DNA repair; go_function DNA binding; ATP binding; nucleic acid binding; helicase activity; go_function DNA binding; ATP binding; nucleic acid binding; helicase activity
Phenol 2-monooxygenase (Phenol hydroxylase); go_function monooxygenase activity; go_process aromatic compound metabolism; electron transport
go_process regulation of cell cycle; DNA replication initiation
Fungal specific transcription factor; go_function DNA binding
hypothetical protein occurs in about 10 places in the P. stipitis genome
go_function DNA binding; go_component nucleosome; nucleus; go_process nucleosome assembly
go_function dihydrofolate reductase activity; go_process glycine biosynthesis; nucleotide biosynthesis
Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1, 6-mannosyltransferase (Mannosyltransferase ALG12)
SIT4-Associating Protein ser/thr phosphatase involved in G1/S transition
ser/thr phosphatase involved in G1/S transition related to SAP155, SAP185, and SAP190, all of which associate with the SIT4 protein phosphatase
Has EST support; contains amidotransferase and phosphosugar isomerase domains large fused protein of putative glutamine amidotransferase and glutamate carboxypeptidase
Glucosamine 6-phosphate synthetases, contain amidotransferase and phosphosugar isomerase domains Cell wall/membrane/envelope biogenesis; go_process metabolism; go_process metabolism
adenylate cyclase (ATP pyrophosphate-lyase) (Adenylyl cyclase)
go_function guanylate cyclase activity; catalytic activity; go_process intracellular signaling cascade; signal transduction
similar to ELMO3 Engulfment and cell motility
nucleolar DEAD-box protein required for synthesis of 60S ribosomal subunits
ATP-dependent RNA helicase nucleolar DEAD-box protein required for synthesis of 60S ribosomal subunits; go_function nucleic acid binding; helicase activity; ATP binding
Has EST support; involved in transport between the late Golgi and endosome
involved in transport between the late Golgi and endosome
CTA4-like zinc finger transcription factor (CTA4) (HAP1) (CIP1); go_component nucleus; go_function transcription factor activity; zinc ion binding; go_process regulation of transcription, DNA-dependent
Glucose 1-dehydrogenase peroxisomal 2,4- dienoyl-CoA reductase
peroxisomal 2,4- dienoyl-CoA reductase Glucose 1-dehydrogenase (BACTERIAL); go_function oxidoreductase activity; go_process metabolism
go_function glycerone kinase activity; go_process glycerol metabolism
Ribose-5-phosphate isomerase B (Phosphoriboisomerase B) (LACB) (RPIB)
Ribose-5-phosphate isomerase B (Phosphoriboisomerase B) (LACB) (RPIB) (Bacterial); go_process carbohydrate metabolism
go_component signal recognition particle (sensu Eukaryota)
Cytochrome P450 52A12 (Alkane hydroxylase 1) (Alkane-inducible p450alk 1) (DH-ALK2)
NADH:flavin oxidoreductase/12-oxophytodienoate reductase; go_function oxidoreductase activity; go_process electron transport
NAPDH dehydrogenase (old yellow enzyme) (OYE22) (EPB7); go_function oxidoreductase activity; go_process electron transport
umarylacetoacetate hydralase 5-carboxymethyl-2-hydroxymuconate delta-isomerase.; go_function catalytic activity; go_process metabolism
major facilitator superfamily multidrug-resistance protein
member of major facilitator superfamily multidrug-resistance protein (HOL4)
dihydroflavonol-4-reductase (maize, petunia, tomato)
mitochondrial aldehyde dehydrogenase succinate semialdehyde dehydrogenase
succinate semialdehyde dehydrogenase similar to NADP-dependent glyceraldehyde-3-phosphate dehydrogenase (Non-phosphorylating glyceraldehyde 3-phosphate dehydrogenase) (Glyceraldehyde-3-phosphate dehydrogenase [NADP+]) (Triosephosphate dehydrogenase); go_function oxidoreductase activity; go_process metabolism