Scheffersomyces stipitis CBS 6054 chromosome 2, complete sequence.
Scheffersomyces stipitis CBS 6054 (Pichia stipitis CBS 6054)
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
Genome sequence of the lignocellulose-bioconverting and xylose-fermenting yeast Pichia stipitis
Submitted (05-JUN-2017) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (12-DEC-2006) US DOE Joint Genome Institute, 2800 Mitchell Drive B100, Walnut Creek, CA 94598-1698, USA
PROVISIONAL REFSEQ: This record has not yet been subject to final\nNCBI review. The reference sequence is identical to CP000496.\nURL -- http://www.jgi.doe.gov/pichia\nJGI Project ID: 3634480\nSource DNA was provided by Jose Laplaza and Thomas Jeffries\n(twjeffri@wisc.edu)\nStock culture is available from Cletus P Kurtzman\n(kurtsman@ncaur.usda.gov)\nContacts: Thomas Jeffries (twjeffri@wisc.edu)\n Paul Richardson (microbes@cuba.jgi-psf.org)\nAnnotation done by JGI-PGF\nManual curation done by the P. stipitis User Community\nFinishing done by JGI-Stanford Human Genome Center\n(www-shgc.stanford.edu)\nUnresolved repeat 2064334-2066234\nUnresolved repeat 2260077-2261344\nUnresolved repeat 2591094-2592404\nThe finished chromosome has no gaps. The sequence has less than one\nerror in 100,000 bp.\nThe JGI and collaborators endorse the principles for the\ndistribution and use of large scale sequencing data adopted by the\nlarger genome sequencing community and urge users of this data to\nfollow them. It is our intention to publish the work of this\nproject in a timely fashion and we welcome collaborative\ninteraction on the project and analysis.\n(http://www.genome.gov/page.cfm?pageID=10506376).\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: INSDC submitter\nAnnotation Status :: Full annotation\nAnnotation Pipeline :: Eukaryotic Annotation Propagation Pipeline\n##Genome-Annotation-Data-END##
Pleiotropic drug resistance proteins (PDR1-15), ABC superfamily; go_component membrane; go_funtion ATP binding; go_process transport
Dimeric dihydrodiol dehydrogenase similar to Glucose--fructose oxidoreductase precursor (GFOR); go_funtion oxidoreductase activity; go_process electron transport; metabolism
involved in secretion; go_funtion molecular function unknown; go_funtion molecular function unknown
go_component integral to membrane; go_funtion molecular function unknown
DNA replicationn factor C multisubunit DNA binding protein and ATPase that acts as a processivity factor for DNA polymerases delta and epsilon and loads proliferating cell nuclear antigen (PCNA) on DNA
go_funtion protein-methionine-S-oxide reductase activity; go_process protein modification
go_funtion cysteine-type endopeptidase activity; ubiquitin thiolesterase activity; go_process ubiquitin-dependent protein catabolism
acetyl-CoA C-acyltransferase, peroxisomal
acetyl-CoA C-acyltransferase, peroxisomal acetyl-CoA C-acyltransferase, putative / 3-ketoacyl-CoA thiolase, putative
go_component membrane; go_funtion phosphatidate cytidylyltransferase activity; go_process phospholipid biosynthesis
go_funtion oxidoreductase activity; go_process electron transport
phenylalanyl-tRNA synthetase alpha subunit, mitochondrial
Phenylalanyl-tRNA synthetase, mitochondrial precursor (Phenylalanine--tRNA ligase) (PheRS); go_funtion phenylalanine-tRNA ligase activity; ATP binding; go_process phenylalanyl-tRNA aminoacylation
mitochondrial 54S ribosomal protein YmL47
go_component intracellular; ribosome; go_funtion structural constituent of ribosome; go_process protein biosynthesis
Molecular chaperone (DnaJ superfamily) J protein type 3
go_funtion copper, zinc superoxide dismutase activity; metal ion binding; go_process superoxide metabolism
Triglyceride lipase-cholesterol esterase
go_funtion carboxylic ester hydrolase activity; go_process lipid metabolism
go_component nucleus; go_funtion nucleic acid binding; zinc ion binding
Regulatory Particle Non-ATPase similar to RPN4 of Candida albicans; go_component nucleus; go_funtion nucleic acid binding; zinc ion binding
possible Polyadenylate-binding protein (RRM superfamily)
Polyadenylate-binding protein (RRM superfamily) simialr to Nucleolin
Mitochondrial respiratory chain complexes assembly protein RCA1 (TAT-binding homolog 12)
Mitochondrial respiratory chain complexes assembly protein RCA1 (TAT-binding homolog 12) very similar to AFG3 (TAT-binding homolog 10); go_funtion ATP binding; metalloendopeptidase activity; go_process proteolysis and peptidolysis
allantoinase (Allantoate amidinohydrolase)
Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family
Subunit i/j of mitochondrial ATP synthase. Similar to S. pombe hypothetical protein
. Similar to S. pombe hypothetical protein; go_funtion hydrogen-transporting ATP synthase activity, rotational mechanism; hydrogen-transporting ATPase activity, rotational mechanism; go_component proton-transporting two-sector ATPase complex; go_process ATP synthesis coupled proton transport
Subunit i/j of mitochondrial ATP synthase
go_component membrane; go_funtion transporter activity; go_process transport
go_component membrane; go_process transport
go_component membrane; go_funtion drug transporter activity; antiporter activity; go_process multidrug transport
filamentous growth, cell polarity and elongation
Mannan endo-1,6-alpha-mannosidase DFG5 precursor (Endo-alpha-1->6-D-mannanase DFG5)
go_funtion catalytic activity; go_process metabolism
go_component nucleus; go_funtion transcription factor activity; zinc ion binding; go_process regulation of transcription, DNA-dependent
go_component clathrin vesicle coat; go_process intracellular protein transport
part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA) ExtraCellular Mutant DEAH-box protein involved in ribosome synthesis
go_funtion nucleic acid binding; helicase activity; ATP binding
substrate-specific activator of APC-dependent proteolysis
go_funtion pepsin A activity; go_process proteolysis and peptidolysis
subunit NUHM of NADH:Ubiquinone Oxidoreductase
go_funtion NADH dehydrogenase (ubiquinone) activity; go_component mitochondrion; go_process mitochondrial electron transport, NADH to ubiquinone
Has EST support; Required for DNA-damage repair, full levels of gene conversion and sporulationbinds URS1 and CAR1RFA1, RFA2, and RFA3 make up RPA
Required for DNA-damage repair, full levels of gene conversion and sporulationbinds URS1 and CAR1RFA1, RFA2, and RFA3 make up RPA; go_funtion nucleic acid binding; go_funtion nucleic acid binding
has possible role in nuclear transport and regulation of pleiotropic drug resistance
go_funtion metalloexopeptidase activity; go_process proteolysis and peptidolysis
go_funtion DNA binding; ATP binding; nucleic acid binding; helicase activity
serine-rich hypothetical cell wall protein
protein involved in cell-cycle regulation of histone transcription
casein kinase II, regulatory (beta) subunit
go_funtion protein kinase CK2 regulator activity; go_component protein kinase CK2 complex
may be involved in assembly/maturation of mitochondrial iron-sulfur proteins
GNAT family acetyltransferase with 2 zinc fingers
go_funtion nucleotidyltransferase activity; go_process biosynthesis
ATPase stabilizing factor 15 kDa protein
Arginyl-tRNA--protein transferase 1 (R-transferase 1) (Arginyltransferase 1) (Arginine-tRNA--protein transferase 1); go_funtion arginyltransferase activity; go_process protein arginylation; regulation of protein catabolism
go_component transcription factor TFIIF complex; go_funtion RNA polymerase II transcription factor activity; ATP binding; go_process transcription initiation from RNA polymerase II promoter
RNA polymerase II transcription initiation factor TFIIF middle subunit
go_component spliceosome complex; go_process RNA splicing
U5 small nuclear ribonucleo protein particle protein
go_funtion urate oxidase activity; go_process purine base metabolism
Ubiquitin--protein ligase molybdopterin-converting factor
Ubiquitin--protein ligase molybdopterin-converting factor (SPAC1A6.10); go_funtion catalytic activity
involved in the accumulation of CoA in the mitochondrial matrix
mitochondrial carrier protein, involved in the accumulation of CoA in the mitochondrial matrix LEU5 does not encode an alpha-IPM synthase; go_component membrane; go_funtion binding; go_process transport; go_component membrane; go_funtion binding; go_process transport
Has EST support; for exit from pachytene
methylates the 21S (mitochondrial) rRNA at position U2791
tandem internal repeat-containing protein
go_funtion lyase activity; go_process amino acid metabolism
required for mitotic chromosome segregation and meiotic recombination with sequence similarity to Saccharomyces cerevisiae YPL008W (CHL1)
go_component nuclear pore; go_process transport
Cytochrome c oxidase assembly protein/Cu2+ chaperone
involved in copper metabolism and assembly of cytochrome oxidase; go_component mitochondrial intermembrane space; go_funtion copper ion binding; copper chaperone activity; go_process copper ion transport
go_component eukaryotic translation initiation factor 2B complex; go_funtion translation initiation factor activity; GTP binding; go_process translational initiation
general negative regulator of transcription
dnaK/HSP70/ BiP family ATPase and chaperone
Has EST support; involved in translocation of nascent polypeptides across the ER membrane
dnaK/HSP70/ BiP family ATPase and chaperone involved in translocation of nascent polypeptides across the ER membrane 8 kDa glucose-regulated protein homolog precursor (Immunoglobulin heavy chain binding protein homolog) (BIP) (GRP78)
cAMP-dependent protein kinase regulatory subunit (PKA regulatory subunit)
go_funtion cAMP-dependent protein kinase regulator activity; go_process signal transduction
go_funtion DNA binding; transcription factor activity; zinc ion binding
go_process intracellular signaling cascade
NAD-dependent histone deacetylase SIR2 (Regulatory protein SIR2) (Silent information regulator 2)
go_component chromatin silencing complex; go_funtion DNA binding; go_process chromatin silencing; regulation of transcription, DNA-dependent
Mannan endo-1,6-alpha-mannosidase DCW1 precursor (Endo-alpha-1->6-D-mannanase DCW1) (Defective cell wall 1)
go_funtion phospholipase activity; go_process phospholipid catabolism
go_component nucleus; go_process regulation of cell cycle
adenine phosphoribosyltransferase (APT1) (APT2); go_process nucleoside metabolism
go_component microtubule associated complex; go_funtion microtubule motor activity; go_process microtubule-based process
go_component membrane; go_funtion nucleobase transporter activity; go_process nucleobase, nucleoside, nucleotide and nucleic acid transport
component of DNA-directed RNA polymerase II holoenzyme
NADPH-dependent cinnamyl-alcohol dehydrogenase.
go_component nucleus; go_funtion transcription factor activity; go_process DNA repair; regulation of transcription
component of RNA polymerase transcription factor
go_funtion zinc ion binding; hydrolase activity
tRNA-specific adenosine deaminase subunit
go_funtion hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; NAD+ synthase (glutamine-hydrolyzing) activity; ATP binding; go_process nitrogen compound metabolism; NAD biosynthesis
protein involved in plasmid maintenance, respiration and cell proliferation (by homology)
protein involved in plasmid maintenance, respiration and cell proliferation
4-aminobutyrate aminotransferase (GABA transaminase)
Ferric reductase, NADH/NADPH oxidase transmembrane component
Ferric reductase, NADH/NADPH oxidase and related proteins transmembrane component (6 domains); go_funtion oxidoreductase activity; go_component membrane; go_process electron transport
DNA polymerase eta subunit Radiation sensitive. Replication fork is protected from inaccurate synthesis by Pol eta in the absence of DNA damage; go_process DNA repair
protein involved in decay of mRNA containing nonsense codons
Nonsense-mediated mRNA decay protein 2 (Up-frameshift suppressor 2); go_funtion RNA binding; go_process protein biosynthesis
mitochondrial 54S ribosomal protein YmL35
ribosomal protein of the large subunit, mitochondrial
go_component nucleus; go_funtion DNA binding; go_process regulation of transcription, DNA-dependent
go_funtion cytochrome-c oxidase activity; go_process electron transport
NuA4 histone acetyltransferase complex component; Yeast homolog of mammalian Ing1; go_funtion DNA binding; go_process regulation of transcription, DNA-dependent; go_funtion DNA binding; go_process regulation of transcription, DNA-dependent
protein required for mother cell-specific HO expression
required for mother cell-specific gene expression
sec-24-like membrane protein involved in ER to Golgi vesicular transport
SED5-binding protein 3 (SEC24-related protein 3) (Lethal with SEC13 protein 1); go_funtion protein binding
Heat shock protein 78, mitochondrial precursor HSP78
heat shock protein of clpb family of ATP-dependent proteases
protein involved in actin organization and endocytosis
PAN1; Involved in actin organization and endocytosis; go_funtion calcium ion binding
Phosphomethylpyrimidine kinase THI21 (HMP-phosphate kinase) (HMP-P kinase)
thiamine biosynthesis; transcribed in the presence of low level of thiamine (10-8M) and turned off in the presence of high level (10-6M) of thiamine. Under the positive control of THI2 and THI3.
go_funtion deaminase activity; go_process purine ribonucleoside monophosphate biosynthesis
go_funtion protein kinase activity; ATP binding; go_process protein amino acid phosphorylation
amino acid transporter; related to the neuronal gamma-aminobutyric acid-glycine vesicular transporters; go_funtion amino acid-polyamine transporter activity; go_component membrane; go_process amino acid transport
converts 3-phosphoglycerate to 2-phosphoglycerate in glycolysis; go_funtion catalytic activity; go_process metabolism
Nucleoporin NSP1 (Nuclear pore protein NSP1) (Nucleoskeletal-like protein) (p110)
go_component nuclear pore; go_funtion structural constituent of nuclear pore
go_funtion porphobilinogen synthase activity; go_process heme biosynthesis
Gdp-GTP Exchange Protein (GEP) for the Rho1p Small GTP-binding Protein
high copy suppressor of cik1 and kar3 deletion mutants.; go_funtion small GTPase regulator activity; go_process intracellular signaling cascade
tRNA splicing, uptake of branched- chain amino acids
E3 ubiquitin protein ligase TOM1 (Temperature dependent-organization in mitotic nucleus protein 1)
E3 ubiqitin ligase required for G2/M transition; go_component intracellular; go_funtion ubiquitin-protein ligase activity; go_process protein modification; ubiquitin cycle
Ribonucleoside-diphosphate reductase large chain 1
go_component ribonucleoside-diphosphate reductase complex; go_funtion ribonucleoside-diphosphate reductase activity; go_process DNA replication
Elongation factor (EF2); go_funtion GTP binding; translation elongation factor activity; go_process protein biosynthesis; translational elongation
Phosphoribosylglycinamide formyltransferase (GART) (GAR transformylase) (5'-phosphoribosylglycinamide transformylase)
go_funtion hydroxymethyl-, formyl- and related transferase activity; go_process biosynthesis
mitochondrial isocitrate dehydrogenase (NAD+) subunit 2
go_funtion oxidoreductase activity; go_process metabolism
involved in glycosyl phosphatidyl inositol synthesis
Involved in glycosyl phosphatidyl inositol synthesis most likely an alpha 1,2 mannosyltransferase utilized for addition of the fourth, side-branching mannose onto the GPI core structure.
go_funtion phospholipase C activity; go_process signal transduction; intracellular signaling cascade
hexose transporter of the major facilitator superfamily
go_component integral to membrane; go_funtion transporter activity; go_process transport
go_funtion DNA ligase (ATP) activity; ATP binding; go_component intracellular; go_process DNA replication; DNA repair; DNA recombination
small subunit of ribonucleotide reductase
go_funtion ribonucleoside-diphosphate reductase activity; go_process deoxyribonucleoside diphosphate metabolism
go_funtion hydrolase activity; catalytic activity
Class 2 transcription repressor NC2, beta subunit (Dr1)
Negative Cofactor B2 is the beta subunit of a negative regulator of RNA polymerase II holoenzyme. It is homologous to the Dr1 subunit of the mammalian NC2 (negative cofactor2); go_funtion DNA binding
Required for efficient translocation of protein precursors across the ER membrane
hypoxanthine guanine phosphoribosyltransferase
hypoxanthine guanine phosphoribosyltransferase;Xanthine Phosphoribosyl Transferase (XPT)
ubiquitin-dependent protein catabolism; go_process ubiquitin-dependent protein catabolism
Suppressor of mRNA export mutant; go_funtion protein transporter activity; go_component nucleus; nuclear pore; cytoplasm; go_process protein-nucleus import, docking
involved in pre-rRNA processing and ribosome assembly
related to various bacterial aminotransferases
related to various bacterial aminotransferases; para-AminoBenZoic acid (PABA) biosynthesis. Third enzymatic step in para-Aminobenzoic acid biosynthesis
Phosphoserine phosphatase (PSP) (O-phosphoserine phosphohydrolase) (PSPase); go_funtion catalytic activity; go_process metabolism
NAPDH dehydrogenase (old yellow enzyme) (EPB7) (OYE22); go_funtion oxidoreductase activity; go_process electron transport
lipid biosynthesis and multidrug resistance
involved in pleiotropic drug resistance by controlling lipids in various cellular compartments; positively regulated by PDR1; putative phosphatidylinositol transfer protein
RNA polymerase I specific transcription initiation factor RRN7
aldehyde dehydrogenase some similarity to glyceraldehyde-3-phosphate dehydrogenase (GAPN); go_funtion oxidoreductase activity; go_process metabolism
40S ribosomal protein S24 (RP50); go_component intracellular; ribosome; go_funtion structural constituent of ribosome; go_process protein biosynthesis
cytoplasmic protein involved in fusion of post-Golgi vesicles with the plasma membrane. The Exocyst complex is required for exocytosis
Vacuolar transporter chaperone 1 (Phosphate metabolism protein 4) (Negative regulator of CDC42 protein 1)
probable Allantoinase similarity to bacterial genes; go_funtion hydrolase activity
mitochondrial trans-2-enoyl-CoA reductase 2
trans-2-enoyl-CoA reductase 2, mitochondrial precursor (Yong-Su Jin[2006-01-06 12:05:17]); go_funtion alcohol dehydrogenase activity, zinc-dependent; zinc ion binding
Arabinose-proton symporter (Arabinose transporter)
Arabinose-proton symporter (Arabinose transporter) [Klebsiella aerogenes] (ARAE); go_component integral to membrane; go_funtion transporter activity; go_process transport
Zinc-finger-containing protein with similarity to Gcs1p and Sps18p; go_component nucleus; go_funtion DNA binding
go_funtion protein translocase activity; go_component mitochondrial inner membrane presequence translocase complex; go_process intracellular protein transport
kynurenine 3-monooxygenase, mitochondrial precursor (Biosynthesis of nicotinic acid protein 4)
go_funtion monooxygenase activity; go_process aromatic compound metabolism
go_funtion cysteine-type peptidase activity; go_process proteolysis and peptidolysis
26S protease regulatory subunit 4 homolog (TAT-binding homolog 5)
TAT-binding homolog 5; go_funtion ATP binding
26S protease regulatory subunit 4-like protein
go_funtion oxidoreductase activity, acting on NADH or NADPH; go_component mitochondrial inner membrane; go_process electron transport
go_funtion transferase activity, transferring phosphorus-containing groups; go_process tRNA splicing
go_funtion metal ion transporter activity; go_component membrane; go_process metal ion transport
go_funtion catalytic activity; nutrient reservoir activity
mitochondrial 54S ribosomal protein RML2
go_funtion hydrogen-transporting ATP synthase activity, rotational mechanism; hydrogen-transporting ATPase activity, rotational mechanism; go_component proton-transporting two-sector ATPase complex; go_process ATP synthesis coupled proton transport
go_funtion ubiquitin conjugating enzyme activity; go_process protein modification; ubiquitin cycle
protein with possible role during mitosis
go_funtion phosphatase activator activity
diacylglycerol pyrophosphate phosphatase
S-adenosylmethionine synthetase (Methionine adenosyltransferase) (AdoMet synthetase); go_funtion methionine adenosyltransferase activity; ATP binding; go_process one-carbon compound metabolism
90S preribosome/SSU processome component KRR1
go_component nucleus; go_process ribosome biogenesis
S. cerevisiae homolog is necessary for sensitivity to a killer toxin (SMK toxin) produced by Pichia Farinosa
pre-mRNA splicing factor RNA helicase of DEAD box family
hypothetical beta-1,6-N-acetylglucosaminyltransferase
similar to cell wall integrity and stress response component 2
Peroxisomal catalase (PXP-9) (CATA); go_funtion catalase activity; go_process electron transport; response to oxidative stress
mitochondrial 54S ribosomal protein YmL19
alpha-D-glucosidase (maltase) (alpha-amylase) (MAL2) (MALT); go_funtion alpha-amylase activity; go_process carbohydrate metabolism
maltose permease some smilarity to Candida albicans MAL31 and Candida intermedia GXS1; go_component integral to membrane; go_funtion transporter activity; go_process transport
RHO small monomeric GTPase signal transduction
go_funtion GTP binding; go_process small GTPase mediated signal transduction
serine-threonine kinase, subunit of RNA Pol TFIIK
cyclin-dependent serine-threonine kinase 7, subunit of RNA Pol TFIIK; go_funtion protein kinase activity; ATP binding; go_process protein amino acid phosphorylation
go_component nucleus; go_funtion DNA binding; transcription factor activity; go_process regulation of transcription, DNA-dependent
go_funtion alcohol dehydrogenase activity, zinc-dependent; zinc ion binding
glycosyl phosphatidylinositol (GPI) synthesis
GPI-alpha-mannosyltransferase III (GPI10/PIG-B) involved in glycosylphosphatidylinositol anchor biosynthesis
Oligosaccharyltransferase, gamma subunit
Catalyzes the transfer of oligosaccharide from dolichol-oligosaccharide donor to consensus glycosylation acceptor sites (asparagines) in newly synthesized proteins
go_component nucleus; go_funtion transcription factor activity; zinc ion binding; DNA binding; go_process regulation of transcription, DNA-dependent; transcription
Glyceraldehyde-3-phosphate dehydrogenase
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH); go_funtion glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity; go_process glycolysis
short-chain alcohol dehydrogenase retinol dehydrogenase
short-chain alcohol dehydrogenase retinol dehydrogenase Protochlorophyllide reductase
transcription factor, contains a PHD finger motif
go_funtion hydrolase activity, hydrolyzing O-glycosyl compounds; go_process carbohydrate metabolism
hydrolase activity, hydrolyzing O-glycosyl compounds
Has EST support. upregulated 2-4 fold on XOL
6-phosphofructokinase, alpha subunit [EC:2.7.1.11] [KO:K00850] (Phosphofructokinase 1) (Phosphohexokinase) (6PF-1-K alpha subunit); go_component 6-phosphofructokinase complex; go_funtion 6-phosphofructokinase activity; go_process glycolysis
Heat shock transcription factor; go_component nucleus; go_funtion transcription factor activity; go_process regulation of transcription, DNA-dependent
delta-1-pyrroline-5-carboxylate dehydrogenase
DNA/RNA helicase MER3/SLH1, DEAD-box superfamily; go_component nucleus; go_funtion nucleic acid binding; helicase activity; ATP binding; type III site-specific deoxyribonuclease activity; go_process DNA restriction-modification system
ATP-dependent RNA helicase HAS1; go_funtion nucleic acid binding; helicase activity; ATP binding
DNA polymerase delta small subunit (Hydroxyurea sensitive protein HYS2)
Exosomal 3'-5' exoribonuclease complex, subunit Rrp44/Dis3
SSD1 protein (SRK1 protein) Exosomal 3'-5' exoribonuclease complex, subunit Rrp44/Dis3; go_funtion RNA binding; ribonuclease activity
go_funtion GTP cyclohydrolase I activity; go_process biosynthesis
glutamyl-tRNA (Gln) amidotransferase subunit A; go_funtion amidase activity
Methionyl-tRNA synthetase, cytoplasmic (Methionine--tRNA ligase) (MetRS); go_funtion tRNA ligase activity; ATP binding; go_process tRNA aminoacylation for protein translation
go_funtion phosphatidylserine decarboxylase activity; go_process phospholipid biosynthesis
GTP binding signal recognition particle receptor
GTP binding Signal Recognition Particle receptor alpha subunit homolog (SR-alpha) (Docking protein alpha) (DP-alpha) (G domain); go_component signal recognition particle (sensu Eukaryota); go_funtion RNA binding; GTP binding; go_process SRP-dependent cotranslational protein-membrane targeting
methionyl-tRNA synthetase, mitochondrial
go_funtion tRNA ligase activity; ATP binding; go_process tRNA aminoacylation for protein translation
TAT-binding homolog 7, AAA ATPase family
TAT-binding homolog 7, AAA ATPase family protein; go_funtion ATP binding
TAT-binding protein-like protein 7, AAA ATPase family
go_funtion positive transcription elongation factor activity; zinc ion binding; go_component nucleus; go_process positive regulation of transcription
COX18; cytochrome c oxidase assembly protein
Inner membrane protein translocase involved in respiratory chain assembly; COX18; required for export of the Cox2p C terminus from the mitochondrial matrix to the intermembrane space; go_component membrane; go_process signal transduction
go_funtion RNA binding; endoribonuclease activity
go_funtion adenosylhomocysteinase activity; go_process one-carbon compound metabolism
regulates glutamine-repressible gene products
go_component nucleus; go_funtion transcription factor activity; go_process regulation of transcription, DNA-dependent
Putative serine proteinase inhibitor (KU family) with thrombospondin repeats
hypothetical protein Putative serine proteinase inhibitor (KU family) with thrombospondin repeats; go_funtion heme binding; electron transporter activity; go_process electron transport
mitochondrial matrix iron-sulfur protein
Ferredoxin mitochondrial matrix iron-sulfur protein; go_funtion electron transporter activity; go_process electron transport
go_component integral to membrane; go_process intracellular protein transport
multidrug-resistance type transporter aminotriazole resistance
multidrug-resistance type transporter; aminotriazole resistance
go_component Golgi cis-face; go_process ER to Golgi transport
part of protein complex with Sin3p and Stb1p
go_funtion aminomethyltransferase activity
Calcium/calmodulin-dependent protein kinase
Permease of the major facilitator superfamily
go_component membrane; go_funtion transporter activity; go_process oligopeptide transport
Has EST support; involved in adding the 4th and 5th mannose residues of O-linked glycans
involved in adding the 4th and 5th mannose residues of O-linked glycans
go_funtion catalytic activity; go_process biosynthesis
go_component proteasome core complex (sensu Eukaryota); go_funtion endopeptidase activity; go_process ubiquitin-dependent protein catabolism
Oligosaccharyltransferase catalyzes the transfer of oligosaccharide from dolichol-oligosaccharide donor to consensus glycosylation acceptor sites (asparagines) in newly synthesized proteins in ER lumen; go_component endoplasmic reticulum; integral to membrane; go_funtion dolichyl-diphosphooligosaccharide-protein glycotransferase activity; go_process protein amino acid glycosylation
Glycolipid 2-alpha-mannosyltransferase (alpha-1,2-mannosyltransferase)
go_component membrane; go_funtion glycolipid 2-alpha-mannosyltransferase activity; go_process protein amino acid glycosylation
Has EST support; involved in n-linked and o-linked glycosylation
involved in n-linked and o-linked glycosylation; go_component membrane; go_funtion glycolipid 2-alpha-mannosyltransferase activity; go_process protein amino acid glycosylation; go_component membrane; go_funtion glycolipid 2-alpha-mannosyltransferase activity; go_process protein amino acid glycosylation
Has EST support; contains the peptidase M41 domain Mitochondrial respiratory chain complexes assembly protein AFG3 (TAT-binding homolog 10)
TAT-binding homolog 10; contains the peptidase M41 domain Mitochondrial respiratory chain complexes assembly protein AFG3; go_funtion ATP binding; metalloendopeptidase activity; go_process proteolysis and peptidolysis; go_funtion ATP binding; metalloendopeptidase activity; go_process proteolysis and peptidolysis
go_funtion protein transporter activity; go_process intracellular protein transport
go_component membrane; integral to membrane; go_funtion ATP binding; go_process transport
DNA-dependent ATPase of the nucleotide excision repair factor 4 complex
ubiquitin ligase (cullin) of SCF involved in cell cycle control
Cell division control protein 53 (Cullin A) acts together with Cdc4p and Cdc34p to control the G1-S phase transition, assists in mediating the proteolysis of the Cdk inhibitor Sic1p in late G1; go_process cell cycle
Encodes a protein with three regions (ABC) that is spliced to yield the extein AC & the intein B AC is a 69K vacuolar (H+)-ATPase & B is a 50K site-specific endonuclease named VDE (PI-SceI) that is homologous to HO; go_component proton-transporting two-sector ATPase complex; go_funtion ATP binding; hydrogen-transporting ATP synthase activity, rotational mechanism; hydrogen-transporting ATPase activity, rotational mechanism; DNA binding; endonuclease activity; go_process ATP synthesis coupled proton transport; ATP biosynthesis; protein splicing
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 9
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 9 (NUEM)(NUO)
Has EST support; contains WSC domain similar to TOS1 precursor (Target of SBF 1)
contains WSC domain similar to TOS1 precursor (Target of SBF 1)
RNA helicase involved in spliceosome disassembly
go_funtion ribose-5-phosphate isomerase activity; go_process pentose-phosphate shunt, non-oxidative branch
Has EST support. Expressed under aerobic conditions
40S ribosomal protein S7-A (RP30); go_component intracellular; ribosome; go_funtion structural constituent of ribosome; go_process protein biosynthesis
transcriptional activator leucine zipper
Has EST support; Identified in a hunt for mutants that activate OCH1 transcription Cell morphogenesis protein PAG1
Identified in a hunt for mutants that activate OCH1 transcription Cell morphogenesis protein PAG1
Oleate-induced peroxisomal protein POX18 (Lipid-transfer protein) (PXP-18)
Ca2+-transporting P-type ATPase strongly induced under oxygen limitation May be involved in depleting cytosol of Ca2+ ions; go_component membrane; go_funtion ATP binding; hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; catalytic activity; go_process cation transport; metabolism
go_funtion carboxy-lyase activity; go_process amino acid metabolism
go_component nucleus; go_funtion nucleic acid binding
Fork head protein homolog 2; go_component nucleus; go_funtion transcription factor activity; go_process regulation of transcription, DNA-dependent
emp24/gp25L/p24 family of membrane trafficking proteins
go_component membrane; go_funtion protein carrier activity; go_process intracellular protein transport
chitin synthase (CHS2); go_funtion chitin synthase activity; go_process chitin biosynthesis
go_component membrane; go_funtion ATP binding; hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; catalytic activity; go_process cation transport; metabolism
fungal transcriptional regulatory protein
Actin-like protein ARP9 (Chromatin structure remodeling complex protein ARP9) (SWI/SNF complex component ARP9)
go_funtion DNA ligase (ATP) activity; ATP binding; go_process DNA replication; DNA repair; DNA recombination
glycerol-3-phosphate O-acyltransferase (GPT1)
Glycerol-3-phosphate O-acyltransferase 1 (G-3-P acyltransferase 1) (Dihydroxyacetone phosphate acyltransferase 1) (DHAP-AT 1) (Glycerol-3-phosphate / dihydroxyacetone phosphate acyltransferase 1); go_funtion acyltransferase activity; go_process metabolism
DNA ATP-dependent helicase similar to Snf2p
similar to Snf2p; go_funtion DNA binding; ATP binding; nucleic acid binding; helicase activity
go_component membrane; go_funtion molecular function unknown
go_component intracellular; ribosome; go_funtion structural constituent of ribosome; nucleic acid binding; go_process protein biosynthesis
5'-phosphoribosylformyl glycinamidine synthetase
16-kDa RNA polymerase subunit (common to polymerases I, II and III)
UTP-glucose-1-phosphate uridylyltransferase
go_funtion nucleotidyltransferase activity; go_process metabolism
dityrosine transporter A(acid, azole) Q(quinidine) Resistance
dityrosine transporter A (AQR2)(acid, azole) Q(quinidine) Resistance; go_component integral to membrane; go_funtion transporter activity; go_process transport
go_component membrane; go_funtion binding; go_process transport
mitochondrial 2-oxodicarboxylate carrier 1
go_component membrane; go_funtion serine-type peptidase activity; dipeptidyl-peptidase IV activity; go_process proteolysis and peptidolysis
involved in nuclear export of pre-ribosomes
involved in nuclear export of pre-ribosomes; go_funtion molecular function unknown; go_funtion molecular function unknown
putative Fungal transcriptional regulatory protein
Regulator of drug sensitivity DNA-binding proteins Bright/BRCAA1/RBP1 and related proteins containing BRIGHT domain; go_component nucleus; go_funtion transcription factor activity; zinc ion binding; go_process regulation of transcription, DNA-dependent
go_funtion peptidase activity; go_process proteolysis and peptidolysis
go_funtion DNA binding; DNA-directed RNA polymerase activity; go_process transcription
RNA polymerase II transcription factor B subunit 2 (RNA polymerase II transcription factor B p52 subunit) (RNA polymerase II transcription factor B 52 kDa subunit)
go_component nucleus; go_funtion transcription factor activity; go_process DNA repair; regulation of transcription, DNA-dependent
ribonucleoside-diphosphate reductase alpha subunit
Ribonucleotide reductase (ribonucleoside-diphosphate reductase) large subunit; go_component ribonucleoside-diphosphate reductase complex; go_funtion ribonucleoside-diphosphate reductase activity; go_process DNA replication
go_funtion two-component response regulator activity; DNA binding; go_process two-component signal transduction system (phosphorelay); regulation of transcription, DNA-dependent
Dead-Box Protein 8, ATP-dependent helicase involved in rRNA processing
Transcription factor IIIB 70 kDa subunit (TFIIIB) (B-related factor) (BRF)
go_component nucleus; transcription factor complex; go_funtion RNA polymerase II transcription factor activity; go_process regulation of transcription, DNA-dependent; transcription initiation from RNA polymerase II promoter
required for normal organization of the actin cytoskeleton and passage through Start
go_process regulation of transcription, DNA-dependent
Malonyl CoA-acyl carrier protein transacylase (MCT)
Malonyl CoA-acyl carrier protein transacylase (MCT) (bacterial); go_funtion transferase activity; go_process metabolism
methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formate--tetrahydrofolate ligase; go_funtion catalytic activity; formate-tetrahydrofolate ligase activity; ATP binding; go_process folic acid and derivative biosynthesis
ferric reductase transmembrane component (Ferric-chelate reductase)
ferric reductase transmembrane component (7 domains) (Ferric-chelate reductase); go_funtion oxidoreductase activity; go_component membrane; go_process electron transport
succinate--CoA ligase (GDP-forming) beta chain (LSC2)
beta subunit of succinyl-CoA ligase (synthetase ATP-forming), a mitochondrial enzyme of the TCA cycle; go_funtion catalytic activity; go_process metabolism
Autophagy-related protein 7 (Autophagy-related E1-like activating enzyme ATG7)
glucosyltransferase required for N-linked glycosylation pathway
Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase (Dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase)
go_funtion guanyl-nucleotide exchange factor activity; go_process intracellular signaling cascade
antioxidant and copper/iron homeostasis protein
go_funtion metal ion binding; go_process metal ion transport
oligomycin resistance ATP-dependent permease
Mitotic spindle checkpoint protein BUB3, WD repeat superfamily
DNA-directed DNA polymerase epsilon, catalytic subunit A
go_funtion nucleotide binding; DNA binding; DNA-directed DNA polymerase activity; 3'-5' exonuclease activity; go_process DNA replication
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] (Trehalose-6-phosphate synthase) (UDP-glucose-glucosephosphate glucosyltransferase); go_funtion alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity; go_process trehalose biosynthesis
vacuolar ATPase V0 domain subunit c' (17 kDa)
go_funtion hydrogen-transporting ATP synthase activity, rotational mechanism; hydrogen-transporting ATPase activity, rotational mechanism; go_component membrane; proton-transporting two-sector ATPase complex; go_process ATP synthesis coupled proton transport
6-phosphofructokinase beta subunit (Phosphofructokinase 2) (Phosphohexokinase) (6PF-1-K beta subunit) (CaPFK2)
go_component 6-phosphofructokinase complex; go_funtion 6-phosphofructokinase activity; go_process glycolysis
translocase of outer mitochondrial membrane
go_funtion voltage-gated ion-selective channel activity; go_component mitochondrial outer membrane; go_process anion transport
Phosphatidylinositol-4-phosphate 5-kinase and related FYVE finger-containing proteins Signal transduction mechanisms
Rhomboid family proteins Function unknown
Has EST support; a heterotrimeric GTP-binding protein SUI2 encodes the alpha subunit GCD11 encodes the gamma subunit
beta subunit of translation initiation factor eIF-2; a heterotrimeric GTP-binding protein SUI2 encodes the alpha subunit GCD11 encodes the gamma subunit; go_funtion translation initiation factor activity; go_process translational initiation; go_funtion translation initiation factor activity; go_process translational initiation
YAR1 encodes a 200-amino-acid protein with two ANK repeat motifs and an acidic C terminus rich in PEST-like sequences
Zn-binding nucleotide exision repairosome
go_component nucleus; go_funtion damaged DNA binding; go_process nucleotide-excision repair
Heat shock protein 90 homolog upregulated at least 20 fold under aerobic conditions; go_funtion ATP binding; go_process protein folding
putative short chain dehydrogenase Glucose/ribitol dehydrogenase; go_funtion oxidoreductase activity; go_process metabolism
mitochondrial outer membrane specialized import receptor
FK506 binding protein proline rotamase rapamycin-binding protein
go_component nucleus; small nucleolar ribonucleoprotein complex
go_funtion protein transporter activity; go_process protein secretion
WDR repeat protein putative Transfer RNA methyltransferase
protein that interacts with Nap1, which is involved in histone assembly
go_component intracellular; ribosome; go_funtion structural constituent of ribosome; go_process translational elongation
Iron sulfur cluster assembly protein 1, mitochondrial precursor (Iron sulfur cluster scaffold protein 1)
Iron binding protein involved in Fe-S cluster formation Iron sulfur cluster assembly protein 1, mitochondrial precursor (Iron sulfur cluster scaffold protein 1)
1-Acyl dihydroxyacetone phosphate reductase
Has EST support; MMAP can rescue MHP1 null mutant; similar to mammalian MAP4 proteins
MMAP can rescue MHP1 null mutant; similar to mammalian MAP4 proteins
nicotinate phosphoribosyl transferase NAD(+) salvage pathway; go_funtion nicotinate phosphoribosyltransferase activity; go_process pyridine nucleotide biosynthesis
go_funtion protein transporter activity; go_component nucleus; nuclear pore; cytoplasm; go_process protein-nucleus import, docking
Nuclear-encoded mitochondrial protein member of the heat shock protein 70 (HSP70) family
Has EST support; most similar to Escherichia coli DnaK protein; acts as a chaperone for protein import across the inner membrane subunit of Endo.SceI endonuclease
most similar to Escherichia coli DnaK protein; acts as a chaperone for protein import across the inner membrane subunit of Endo.SceI endonuclease
highly conserved MFS family transporter multidrug-resistance type transporter (MFS2) (ATR2)
histidinol and sodium permease homologous to ScHOL1 (HOL1)
mitochondrial phosphate transport protein
DNA-directed RNA polymerase I subunit A34
Protein kinase homolog, mutant is salt and pH sensitive
Gluconate transport-inducing protein required for gluconate-H+ symport
go_component transcription factor TFIIE complex; go_funtion RNA polymerase II transcription factor activity; go_process transcription initiation from RNA polymerase II promoter
go_funtion protein transporter activity; go_component intracellular; nucleus; go_process protein-nucleus import
Chromatin structure remodeling complex protein SFH1 (SNF5 homolog 1)
go_component nuclear chromosome; go_process chromatin remodeling
tRNA-specific adenosine-34 deaminase subunit
Bud site selection protein BUD6 (Actin interacting protein 3)
Karyopherin Functions in nuclear transport of proteins
go_funtion GTP binding; go_process protein biosynthesis
go_funtion 4-nitrophenylphosphatase activity; alkaline phosphatase activity; go_process dephosphorylation; histone modification; histone dephosphorylation
go_funtion two-component sensor molecule activity; go_process two-component signal transduction system (phosphorelay)
putative response regulator phosphotransferase
catalyzes the transfer of mannose from Dol-P-Man to lipid-linked oligosaccharides
Nitrilase, arylacetone-specific (Arylacetonitrilase)
Nitrilase, arylacetone-specific (Arylacetonitrilase) (bacterial); go_funtion hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; go_process nitrogen compound metabolism
major facilitator superfamily multidrug-resistance protein
member of major facilitator superfamily multidrug-resistance protein
Salicylate hydroxylase (Salicylate 1-monooxygenase)
Salicylate hydroxylase (Salicylate 1-monooxygenase) Kynurenine 3-monooxygenase and related flavoprotein monooxygenases; go_funtion monooxygenase activity; go_process aromatic compound metabolism
fumarylacetoacetate hydralase 5-carboxymethyl-2-hydroxymuconate delta-isomerase.; go_funtion catalytic activity; go_process metabolism
putative transcriptional regulatory protein
putative fungal specific transcriptional regulatory protein; go_component nucleus; go_funtion transcription factor activity; zinc ion binding; DNA binding; go_process regulation of transcription, DNA-dependent; transcription
go_funtion aminoacyl-tRNA hydrolase activity; go_process protein biosynthesis
Peroxisomal long-chain fatty acid import protein 1 (Peroxisomal ABC transporter 2)
Homolog of the human adrenoleukodystrophy transporter forms a heterodimer with Pxa1p of two half ATP-binding cassette transporters in the peroxisome membrane; go_component membrane; go_funtion ATP binding; go_process transport
Sphingosine kinase, involved in sphingolipid metabolism Lipid transport and metabolism
Sphingosine kinase (SPHK), involved in sphingolipid metabolism Lipid transport and metabolism; go_funtion diacylglycerol kinase activity; go_process protein kinase C activation
3-phosphoglycerate dehydrogenase, serine biosynthesis
go_funtion oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; amino acid binding; go_process L-serine biosynthesis; metabolism
go_component microtubule associated complex; go_funtion motor activity; ATP binding
Beta-galactosidase (Lactase) (BGAL); go_component beta-galactosidase complex; go_funtion hydrolase activity, hydrolyzing O-glycosyl compounds; beta-galactosidase activity; go_process carbohydrate metabolism
myotubularin-related dual specificity phosphatase
Phosphoinositide 3-phosphatase (Yeast myotubularin-related protein 1)
mitochondrial protoporphyrinogen oxidase
mitochondrial protoporphyrinogen oxidase converts protoporphyrinogen IX to protoporphyrin IX (in synthesis of heme)
arginine methyltransferase-interacting RING finger protein
Ferric reductase, NADH/NADPH oxidase transmembrane component (8 domains)
mitochondrial protein involved in respiration
Mitochondrial protein Surfeit 1/SURF1/SHY1, required for expression of cytochrome oxidase
Dihydroorotate dehydrogenase, mitochondrial precursor (Dihydroorotate oxidase) (DHOdehase) (DHODase) (DHOD); go_component membrane
uridine kinase converts ATP and uridine to ADP and UMP; go_funtion ATP binding; kinase activity; go_process biosynthesis
alanine aminotransferase (Glutamic--pyruvic transaminase) (GPT) (Glutamic--alanine transaminase); go_funtion transaminase activity; go_process biosynthesis
Acetyl-CoA acetyltransferase IA (Peroxisomal acetoacetyl-CoA thiolase) (Thiolase IA)
succinate semialdehyde dehydrogenase NADP+ linked
succinate semialdehyde dehydrogenase similar to NADP-dependent glyceraldehyde-3-phosphate dehydrogenase (Non-phosphorylating glyceraldehyde 3-phosphate dehydrogenase) (GAPN); go_funtion oxidoreductase activity; go_process metabolism
A-agglutinin attachment subunit precursor
Cell wall synthesis protein KRE9 precursor
go_component extracellular region; go_process cell wall biosynthesis
glucan synthase subunit involved in cell wall assembly
go_funtion metalloexopeptidase activity; peptidase activity; go_process proteolysis and peptidolysis
Fungal specific transcription factor; go_component nucleus; go_funtion transcription factor activity; zinc ion binding; DNA binding; go_process regulation of transcription, DNA-dependent; transcription
Fungal specific transcription factor; go_funtion DNA binding; zinc ion binding
calcineurin responsive zinc-finger; go_component nucleus; go_funtion nucleic acid binding; zinc ion binding
Predicted cell surface protein homologous to bacterial outer membrane proteins
Predicted cell surface protein homologous to bacterial outer membrane proteins SAM50-like protein
cyclophilin type peptidyl-prolyl cis-trans isomerase
RNA polymerase II holoenzyme cyclin-like subunit
Longevity-assurance protein 1 (Longevity assurance factor 1)
Ubiquinone/menaquinone biosynthesis methyltransferase ubiE
membrane-bound casein kinase I homolog; go_funtion protein kinase activity; ATP binding; go_process protein amino acid phosphorylation
taurine catabolism dioxygenase similar to Fe(II)-dependent sulfonate/alpha-ketoglutarate dioxygenase; go_funtion oxidoreductase activity; go_process electron transport
Glutathione S-transferase Posttranslational modification, protein turnover, chaperones
Predicted RNA-binding protein Nob1p involved in 26S proteasome assembly
Structural maintenance of chromosome protein 3 (sister chromatid cohesion complex Cohesin, subunit SMC3)
Structural maintenance of chromosome protein 3 (SMC3) (sister chromatid cohesion complex Cohesin, subunit SMC3) Ploidy-related. Shares homology with PLO1
hypothetical protein; occurs 10 times in Pichia stipitis
protein involved in cell cycle control and ion homeostasis
elongation factor 1 gamma domain-containing protein
go_component eukaryotic translation elongation factor 1 complex; go_funtion translation elongation factor activity; go_process translational elongation
assembly of mitochondrial respiratory complexes
which is unique in its ability to bypass thymine dimers during replication, is composed of Rev3p and Rev7p
which is unique in its ability to bypass thymine dimers during replication, is composed of Rev3p and Rev7p; go_funtion nucleotide binding; DNA binding; DNA-directed DNA polymerase activity; 3'-5' exonuclease activity; go_process DNA replication; go_funtion nucleotide binding; DNA binding; DNA-directed DNA polymerase activity; 3'-5' exonuclease activity; go_process DNA replication
membrane-bound alpha-1,6- mannosyltransferase Initiation-specific
membrane-bound alpha-1,6- mannosyltransferase initiates the polymannose outer chain elongation of N-linked glycans
ATP-dependent RNA helicase of DEAD box family
ATP-dependent RNA helicase of DEAD box family; suppressor of uncontrolled mitosis; go_funtion nucleic acid binding; helicase activity; ATP binding
NAD kinase associated with ferric reductase
NAD(+) kinase (Unknown transcript 1 protein); go_funtion NAD+ kinase activity; go_process metabolism
Has EST support; converts nucleoside diphosphates to nucleoside monophosphates to recycle nucleosides and promote transport of additional nucleotide sugars into golgi
converts nucleoside diphosphates to nucleoside monophosphates to recycle nucleosides and promote transport of additional nucleotide sugars into golgi; go_funtion hydrolase activity; go_funtion hydrolase activity
Uncharacterized conserved protein related to ribosomal protein S8E killer toxin resistant; go_component intracellular; ribosome; go_funtion structural constituent of ribosome; go_process protein biosynthesis
nucleolar protein required for ribosomal RNA processing
go_funtion transcription regulator activity; go_component nucleus; go_process regulation of transcription
Mitochondrial oxaloacetate carrier protein
mitochondrial oxaloacetate transport protein; go_component membrane; go_funtion binding; go_process transport
mitochondrial 54S ribosomal protein YmL39
chromatin remodeling complex Adenosinetriphosphatase
chromatin remodeling complex ATPase component of a four subunit chromatin remodeling complex; go_funtion DNA binding; ATP binding; nucleic acid binding; helicase activity; type III site-specific deoxyribonuclease activity; go_process DNA restriction-modification system
subunit of N- oligosaccharyltransferase complex
go_component intracellular; go_funtion DNA binding; endonuclease activity; go_process DNA repair
Involved in nucleocytoplasmic transport may be required for biogenesis of tRNA; go_component nuclear pore; go_process transport
go_funtion transferase activity, transferring hexosyl groups; go_process carbohydrate biosynthesis
Putative serine proteinase inhibitor (KU family)
hypothetical protein with thrombospondin repeats; go_funtion heme binding; electron transporter activity; go_process electron transport
go_funtion catalytic activity; ubiquitin activating enzyme activity; go_process protein modification; ubiquitin cycle
ATP-dependent permease (STE6); go_component membrane; integral to membrane; go_funtion ATP binding; go_process transport
Second and third steps of methylation pathway for phosphatidylcholine biosynthesis
go_funtion N-methyltransferase activity; go_process phospholipid metabolism
carboxylic acid transporter protein (JEN1); go_component integral to membrane; go_funtion transporter activity; go_process transport
seventh step in lysine biosynthesis pathway
Saccharopine dehydrogenase [NADP+, L-glutamate-forming] (Saccharopine reductase)
go_funtion transcription initiation factor activity; go_component nucleus; go_process transcription initiation
hypothetical protein, likely cell wall localized and GPI-anchored mucin like
go_component membrane; go_process protein targeting; intracellular protein transport
protein transport protein SEC61 gamma subunit
pre-mRNA splicing factor affecting 3 splice site choice
go_component transcription factor TFIID complex; go_process transcription initiation
fungal Zn(2)-Cys(6) binuclear cluster zinc finger transcription factor; slight identity to CAT8; transcription factor involved in gluconeogenesis; involved in pleiotropic drug resistance; go_component nucleus; go_component nucleus
Phospho Mannno Transferase; dolichyl-P-mannose-protein mannosyltransferase
Transfers mannosyl residues from dolichyl phosphate-D-mannose to seryl and threonyl residues in proteins; acts in complex with Pmt1p; go_funtion mannosyltransferase activity; go_component membrane; go_process O-linked glycosylation
mitochondrial protein required for iron metabolism
Mitochondrial Fe-S cluster biosynthesis protein ISA2 (contains a HesB-like domain); go_funtion molecular function unknown
Inorganic pyrophosphatase, mitochondrial precursor (Pyrophosphate phospho-hydrolase) (PPase)
go_funtion pyrophosphatase activity; go_component membrane; go_process metabolism
go_funtion ATP binding; kinase activity; go_process phosphorylation
go_component membrane; go_funtion cation transporter activity; go_process cation transport
holo-[acyl-carrier-protein] synthase (Holo-ACP synthase) (4'-phosphopantetheinyl transferase acpS); go_funtion magnesium ion binding; phosphopantetheinyltransferase activity; go_process fatty acid biosynthesis
go_funtion catalytic activity; GMP synthase (glutamine-hydrolyzing) activity; ATP binding; go_process purine nucleotide biosynthesis; GMP biosynthesis
protein farnesyltransferase / geranylgeranyltransferase type I alpha subunit
Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit (CAAX farnesyltransferase alpha subunit) (Ras proteins prenyltransferase alpha) (FTase-alpha) (Type I protein geranyl-geranyltransferase alpha subunit) (GGTase-I-alpha); go_funtion protein prenyltransferase activity; go_process protein amino acid prenylation
go_funtion tRNA isopentenyltransferase activity; ATP binding; go_process tRNA processing
pH-response regulator protein palA/RIM20
go_component nucleus; go_funtion DNA binding
eukaryotic initiation factor 4F subunit p20
go_funtion acetylglutamate kinase activity; go_process amino acid biosynthesis; amino acid metabolism; arginine biosynthesis
N-acetyl-gamma-glutamyl-phosphate reductase and acetylglutamate kinase
Mitochondrial RNA helicase of the DEAD box family
Has EST support; necessary for splicing of several mt introns
60S ribosomal protein L44 (60S ribosomal protein L41); go_component intracellular; ribosome; go_funtion structural constituent of ribosome; go_process protein biosynthesis
putative zinc finger protein; go_funtion DNA binding
go_component actin cytoskeleton; go_funtion structural constituent of cytoskeleton
N-acetylglucosaminyl phosphatidylinositol de-N-acetylase
CAT8 controls the key enzymes of gluconeogenesis
Multidrug resistance-associated protein/mitoxantrone resistance protein, ABC superfamily
Glucose-repressible alcohol dehydrogenase transcriptional effector (Cytoplasmic deadenylase) (Carbon catabolite repressor protein 4)
Lysophospholipase 3 precursor (Phospholipase B 3); go_funtion phospholipase activity |4620; go_process phospholipid catabolism |9395
part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA) DOM34 Interacting Protein
go_funtion protein tyrosine phosphatase activity; go_process protein amino acid dephosphorylation
negative transcriptional regulator; member of the NOT complex, a global negative regulator of transcription; go_funtion transcription regulator activity; go_component nucleus; go_process regulation of transcription
putative golgi membrane protein-sorting protein
retrieval from vacuole to Golgi; go_process intracellular signaling cascade
converts saturated fatty acyl-CoAs into cis-Delta-9 unsaturated fatty acids.; go_funtion oxidoreductase activity
Glycine dehydrogenase [decarboxylating], mitochondrial precursor (Glycine decarboxylase) (Glycine cleavage system P-protein); go_component glycine dehydrogenase complex (decarboxylating); go_funtion glycine dehydrogenase (decarboxylating) activity; go_process glycine metabolism; go_component glycine dehydrogenase complex (decarboxylating); go_funtion glycine dehydrogenase (decarboxylating) activity; go_process glycine metabolism
go_funtion homocysteine S-methyltransferase activity
large subunit of the nuclear pre-mRNA cap-binding protein complex; go_funtion RNA binding; go_process protein biosynthesis
go_component membrane; go_funtion ATP binding; go_process transport
ATP-binding cassette transporter activity
Serine/threonine protein kinase with similarity to protein kinase; go_funtion protein kinase activity; ATP binding; protein serine/threonine kinase activity; go_process protein amino acid phosphorylation
mitochondrial 54S ribosomal protein YmL28
go_funtion phosphopyruvate hydratase activity; go_component phosphopyruvate hydratase complex; go_process glycolysis
kynureninase with role in NAD biosynthesis
Cell division control protein 42 homolog
Cell division control protein 42 homolog Rho GTP-binding protein regulating the cell cycle; go_funtion GTP binding; go_process small GTPase mediated signal transduction
go_funtion DNA binding; go_process regulation of transcription, DNA-dependent
Ca2+/H+ antiporter Similar to sodium/calcium exchangers, including bovine Na+/Ca2+,K+ antiporter putative vacuolar transmembrane protein; go_component integral to membrane
squalene epoxidase(monooxygenase), erosterol biosynthesis
squalene epoxidase an essential enzyme in the ergosterol-biosynthesis pathway catalyzes the epoxidation of squalene to 2,3-oxidosqualene and is the specific target of the antifungal drug terbinafine.; go_funtion monooxygenase activity; go_process aromatic compound metabolism
translation initiation factor eIF-2B epsilon subunit, GEF
Translation initiation factor eIF-2B epsilon subunit (eIF-2B GDP-GTP exchange factor) (Guanine nucleotide exchange factor subunit GCD6) (GCD complex subunit GCD6); go_funtion translation initiation factor activity; go_process regulation of translational initiation
go_component integral to membrane; go_funtion copper ion transporter activity; go_process copper ion transport
U3 snoRNP protein part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA)
transcription factor, member of ADA and SAGA, two transcriptional adaptor/HAT (histone acetyltransferase) complexes
go_component nucleus; go_funtion DNA binding; zinc ion binding
D-Amino acid dehydrogenase (putative); go_funtion oxidoreductase activity; go_process electron transport
Has EST support; involved in cell wall biosynthesis
aspartyl aminopeptidase Aminopeptidase I zinc metalloprotease (M18); go_component vacuole; go_funtion aminopeptidase I activity; go_process proteolysis and peptidolysis
high-affinity permease for basic amino acids
protein involved in silencing Suppressor of Exocyst Mutations
Heterochromatin-associated protein HP1 and related CHROMO domain proteins involved in silencing
Has EST support; involved in the secetory pathway and membrane trafficking
involved in the secetory pathway and membrane trafficking; go_component membrane; go_funtion protein carrier activity; go_process intracellular protein transport; go_component membrane; go_funtion protein carrier activity; go_process intracellular protein transport
Serine/threonine protein kinase involved in cell cycle control; go_funtion molecular function unknown
hypothetical protein of unknown function
required for cell viability in S. cerevisiae
slight similarity to Uncoordinated protein 89
similar to mammalian syntaxin 5; similar to syntaxin and involved in ER to Golgi transport
protein kinase C inhibitor-I, histidine triad nucleotide-binding protein-like protein
Microsomal protein of CDC48/PAS1/SEC18 family of ATPases full length homology to mammalian protein VCP involved in secretion, peroxisome formation and gene expression; go_funtion ATP binding
go_component actin cytoskeleton; go_funtion actin binding; go_process cytoskeleton organization and biogenesis
Protein with homology to mammalian ubiquitin activating (E1) enzyme
Dolichol-phosphate mannosyltransferase (Dolichol-phosphate mannose synthase) (Dolichyl-phosphate beta-D-mannosyltransferase) (Mannose-P-dolichol synthase) (MPD synthase) (DPM synthase)
RNA-binding / Ran zinc finger proteinrotein
conserved hypothetical membrane protein; go_component membrane
UME6 C6 zinc finger URS1-binding protein-like protein
binds multiple proteins involved in cell polarity establishment; go_process intracellular signaling cascade
MUC1-like protein possibly involved in regulation of cell wall synthesis
Ribosomal protein S6 kinase and related proteins
go_funtion protein kinase activity; ATP binding; protein serine/threonine kinase activity; go_process protein amino acid phosphorylation
go_component intracellular; go_funtion ubiquitin thiolesterase activity; go_process ubiquitin-dependent protein catabolism
Leucine permease transcriptional regulator
Probable leukotriene A-4 hydrolase (LTA-4 hydrolase) (Leukotriene A(4) hydrolase)
Probable leukotriene A-4 hydrolase (LTA-4 hydrolase) (LTHA4) (Leukotriene A(4) hydrolase); go_funtion membrane alanyl aminopeptidase activity; go_process proteolysis and peptidolysis
member of triose phosphate translocator family
peptidase C19, ubiquitin C-terminal hydrolase 2
go_funtion 3'-5'-exoribonuclease activity; RNA binding; go_process RNA processing
go_funtion disulfide oxidoreductase activity; oxidoreductase activity; glutamate synthase activity; go_process electron transport; metabolism; glutamate biosynthesis; nitrogen compound metabolism
multicopy suppressor of clathrin deficiency
go_component membrane; go_funtion potassium ion transporter activity; go_process potassium ion transport
NAT3 Catalytic subunit of the NatB N-terminal acetyltransferase, which catalyzes acetylation of the amino-terminal methionine residues of all proteins beginning with Met-Asp or Met-Glu and of some proteins beginning with Met-Asn or Met-Met; go_funtion N-acetyltransferase activity
Phosphatidylinositol 3-kinase VPS34 (PI3-kinase) (PtdIns-3-kinase) (PI3K) (Vacuolar sorting protein 34); go_component phosphoinositide 3-kinase complex; go_funtion phosphotransferase activity, alcohol group as acceptor; inositol or phosphatidylinositol kinase activity; phosphatidylinositol 3-kinase activity
Dephospho-CoA kinase (Dephosphocoenzyme A kinase) (COAE)
Dephospho-CoA kinase (Dephosphocoenzyme A kinase) predicted to catalyze the final step in synthesis of Coenzyme A; go_funtion ATP binding
2-dehydropantoate 2-reductase (Ketopantoate reductase) (KPA reductase) (KPR)
ketopantoate reductase (2-dehydropantoate 2-reductase), has similarity to Cbs2p and yeast; go_funtion 2-dehydropantoate 2-reductase activity; go_process pyrimidine base metabolism
component of Pab1p-stimulated poly(A) ribonuclease
protein that affects bud emergence, intrachromosomal recombination, and nuclear division
go_funtion signal transducer activity; go_process G-protein coupled receptor protein signaling pathway
guanine nucleotide-binding protein alpha subunit
ubiquinol-cytochrome c reductase core subunit 1
go_funtion metalloendopeptidase activity; go_process proteolysis and peptidolysis
mitochondrial 37S ribosomal protein RSM7
membrane anchor in succinate dehydrogenase complex
go_funtion heme binding; go_component mitochondrial membrane; integral to membrane; go_process tricarboxylic acid cycle; electron transport
mitochondrial 37S ribosomal protein MRP2
ATP phosphoribosyltransferase (ATP-PRTase) (ATP-PRT)
go_funtion ATP phosphoribosyltransferase activity; go_process histidine biosynthesis
go_funtion transferase activity; go_process metabolism
protein involved in a late step of 60S ribosomal subunit assembly or modification contains multiple WD repeats interacts with Qsr1p
DNA primase small subunit (DNA primase 48 kDa subunit) (p48); go_funtion DNA primase activity; go_process DNA replication, synthesis of RNA primer
non-ATPase unit of 26S proteasome complex
medium subunit of the clathrin-associated protein complex
fatty acid desaturase Dihydroceramide delta(4)-desaturase; go_funtion oxidoreductase activity
histidine tRNA synthetase Histidine--tRNA ligase.; go_funtion tRNA ligase activity; ATP binding; go_process tRNA aminoacylation for protein translation; protein biosynthesis
go_funtion peroxidase activity; go_process response to oxidative stress
cytoskeletal binding and regulatory protein
probable hexose transporter closely related to D. hansenii proteins some similarity to GXS1; go_component integral to membrane; go_funtion transporter activity; go_process transport
High-affinity Glucose Transporter (putative)
High-affinity glucose transporter, putative some similarity to GXS1; go_component integral to membrane; go_funtion transporter activity; go_process transport
Aglutinin-Like Serine rich hypothetical protein