Micromonas commoda chromosome 1, complete sequence.
Eukaryota; Viridiplantae; Chlorophyta; prasinophytes; Mamiellophyceae; Mamiellales; Mamiellaceae; Micromonas.
Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas
Submitted (22-JUN-2017) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (23-DEC-2008) US DOE Joint Genome Institute, 2800 Mitchell Drive B100, Walnut Creek, CA 94598-1698, USA
PROVISIONAL REFSEQ: This record has not yet been subject to final\nNCBI review. The reference sequence is identical to CP001574.\nURL -- http://www.jgi.doe.gov/MicromonasRCC299\nJGI Project ID: 4000189\nOrganism available from the Center for Culture of Marine\nPhytoplankton (CCMP) and the Roscoff Culture collection (RCC)\nContacts: Alexandra Z. Worden (azworden@mbari.org)\n Igor Grigoriev (IVGrigoriev@lbl.gov)\nAnnotation done by the Micromonas genome consortium as identified\nin the authorship as listed as reference 1 above.\nThis organism was isolated from South Pacific surface waters in\n1998 by S.Boulben. This strain was rendered clonal and axenic in\nthe Worden Lab through plating and a series of antibiotic\ntreatments. Subsequently, the axenic strain was deposited at the\nCCMP (CCMP2709) and RCC (RCC827). RCC299 is also referred to as\nstrain NOUM17.\nThe JGI and collaborators endorse the principles for the\ndistribution and use of large scale sequencing data adopted by the\nlarger genome sequencing community and urge users of this data to\nfollow them. We welcome collaborative interaction on the project.\n(http://www.genome.gov/page.cfm?pageID=10506376).\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: INSDC submitter\nAnnotation Status :: Full annotation\nAnnotation Pipeline :: Eukaryotic Annotation Propagation Pipeline\n##Genome-Annotation-Data-END##
homology to CCMP1545 model; putative uncharacterized protein
BAH-PHD domain-containing protein. ChromDB ID: EBP20101
Succinyl-CoA synthetase (GDP-forming) alpha-subunit; GTP + succinate + CoA = GDP + phosphate + succinyl-CoA; mitochondria precursor: TargetP predicted a 14 aa mTP; expressed
ACBP and Kelch domain containing; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity
thylakoid lumenal protein, chloroplast precursor
both ChloroP and TargetP predict a 36 aa cTP; 29.8 kDa-like
has SpoU domain, SpoU rRNA Methylase family. This family of proteins probably use S-AdoMet.
Radical SAM proteins catalyze diverse reactions, including unusual methylations, isomerization, sulphur insertion, ring formation, anaerobic oxidation and protein radical formation
conserved uncharacterized protein cupA13
peptide deformylase, chloroplast precursor
Peptide deformylase (PDF) (Polypeptide deformylase); [] (DEFM); deformylates methionine, the first step in post-translational maturation of organelle-encoded polypeptides; plant orthologue is targeted to both chloroplast and mitochondria
ribosomal protein S13, chloroplast precursor
adenylyl-sulfate kinase chloroplast precursor
Neurotransmitter:Sodium symporter family
Encodes a ULT-domain containing protein with a C-terminal zinc finger domain. ULT-domain is related to SAND domain.
Der1-like family protein - The endoplasmic reticulum (ER) of the yeast Saccharomyces cerevisiae contains of proteolytic system able to selectively degrade misfolded lumenal secretory proteins
expressed; semiconserved uncharacterized protein cupA50
Intraflagellar Transport or IFT refers to the cellular process essential for the formation and maintenance of eukaryotic cilia and flagella
iron-sulfur cluster scaffold protein, plastid precursor
transcription initiation factor TFIID subunit 1
This model contains a hTAFII28-like protein conserved region.
DNA replication complex GINS protein psf2, probable
expressed; conserved uncharacterized protein cup999
related to a-glycosidases; also annotated as isoamylase-type starch-debranching enzyme; expressed
also annotated as FAM96; expressed; conserved uncharacterized protein cupA49
transcription initiation factor TFIID sub.10
mitochondrial import inner membrane translocase
Has Sam_1 and Tim17 domains; The pre-protein translocase of the mitochondrial outer membrane (Tom) allows the import of pre-proteins from the cytoplasm
S-adenosylmethionine; Alternative splicing variant 1
expressed; Alternative splicing variant 2
eukaryotic translation initiation factor 5A
green lineage poorly conserved protein of unknown function
gcn5-related n-acetyltransferase family protein
uroporphyrinogen decarboxylase chloroplast precursor
expressed; putative uncharacterized protein
U3 small nucleolar ribonucleoprotein component
From Chlamy: DC3, the 21-kDa subunit of the outer dynein arm-docking complex (ODA-DC), is a novel EF-hand protein important for assembly of both the outer arm and the ODA-DC. Synonyms: ODA14 ODA-DC3
PsbB mRNA maturation factor Mbb1,chloroplast precursor
TPR domain containing protein; similar to PsbB mRNA maturation factor Mbb1, chloroplast precursor
related to a-mannosyltransferases; expressed
Xtp3A-related NTP pyrophosphatase; in CCMP1545 this is a fusion protein
chlorophyll a/b-binding protein, psi-associated, chloroplast precursor
ChloroP and Target P predict a 13 aa cTP
All blast hits are DSBA oxidoreductase, presumed to be a thiol oxidoreductase involved in polyketide biosynthesis. This locus has EST support for intron and UTR regions
likely Plastidial delta 12 fatty acid desaturase; expressed
four-cystein-containing hypothetical protein; Alternative splicing variant 2
Similarity to small nuclear ribonucleoprotein Sm D2, also known as snRNP core protein D2; Sm-D2; SNRPD2; Alternative splicing variant 1
ATP phosphoribosyl transferase chloroplast precursor
ATP phosphoribosyl transferase chloroplast precursor (ChloroP and TargetP predict 55aa cTP); expressed
likely chloroplast precursor of a membrane protein of unknown function (Yuh87); expressed uncharacterized protein
chlorophyll a/b-binding protein, chloroplast precursor
Chlorophyll a-b binding protein, chloroplast precursor (LHCI type II); Type II LHCI
Acetyl-CoA Carboxylase (ACC) carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.
Cup93 with UTR added; conserved protein of unknown function
glycosylphosphatidylinositol ethanolamine phosphate transferase
Green algae conserved protein of unknown function Gac1; expressed; conserved uncharacterized protein cupA43
transcription initiation factor TFIIIB, Bdp1 subunit
Conserved green lineage protein of unknown function CUP92; expressed; conserved uncharacterized protein cup92
transcription initiation factor subunit A
TFIID_20kD domain, This family is a member of the Histone superfamily clan. expressed
RNA polymerase II transcription factor B subunit 4
has pfam Tfb4; Members of this family are part of the TFIIH complex which is involved in the initiation of transcription and nucleotide excision repair
conserved uncharacterized protein cupA48
glyceraldehyde-3-phosphate dehydrogenase B
SignalP & TargetP say no TP, ChloroP says 57AA TP
pyridoxal phosphate dependent aminotransferase
B-type asparagine synthetase chloroplast precursor
shows homology to sister chromatid arm cohesin proteins (synaptonemal complex components)
kea1-related potassium hydrogen antiporter
ubiquinone biosynthesis methyltransferase
ribosomal protein L18, chloroplast precursor
SANT domain DNA-binding protein 1; expressed
candidate bifunctional trehalose-6-phosphate synthase/trehalose-6-phosphate phosphatase
flagellar outer dynein arm light chain 8
Synonyms: 8KD FLA14 ODA-LC8 Function (from Chlamy): not recorded; expressed
phosphatidylinositol-4-phosphate 5-kinase
high affinity nitrate transporter accessory protein
One of two, identical to ID 104705 also found on chromosome 1. The third transporter on chromosome 9 seems to be lacking an accessory protein. expressed
First of six ammonium transporters in NOUM17
green algal specific Aspartyl/Asparaginyl beta-hydroxylase
Glp3; DUF339 containing protein of unknown function conserved in the green lineage
IFT52 intraflagellar transport protein-like protein
heat shock binding protein 70, ER luminal
carbohydrate-binding module family 48 protein
candidate a-glucan-binding protein; expressed
5,10-methylene-tetrahydrofolate dehydrogenase/cyclohydrolase
JmjC domain. The JmjC domain belongs to the Cupin superfamily. JmjC-domain proteins may be protein hydroxylases that catalyse a novel histone modification. expressed; hypothetical protein with JmjC domain
structural constituent of nuclear pore, nucleoporin 62
Variant 2; expressed; Alternative splicing variant 1
Variant 1; Alternative splicing variant 2
cytochrome c oxidase assembly protein, mitochondrial
U3 small nucleolar rna-associated protein 18
SIN3 component of histone deacetylase complex
Predicted homolog of Saccharomyces cerevisiae Sin3 protein; Sin3 proteins participate in global histone deacetylase complexes. ChromDB ID: SNT20101; Alternative splicing variant 2
component of dynein regulatory complex of flagellar axoneme
Calmodulin (CaM) is a calcium-binding protein expressed in all eukaryotic cells. It can bind to and regulate a number of different protein targets, thereby affecting many different cellular functions
peptidyl-prolyl cis trans isomerase cyclophilin 59, nuclear
expressed; conserved protein of unknown function
transcription factor IIA, alpha/beta subunit
Putatiave homolog of Saccharomyces cerevisiae PAF1, a RNA polymerase II-associated Paf1p complex subunit
phosphatidic acid phosphatase-related protein
RecA/Rad51/DMC1 proteins are involved in homology searching and strand exchange in homologous recombination. They are involved in DNA repair, telomere maintenance, and meiotic recombination
mitosis protein DIM1/U5snRNP-specific component
Thioredoxin reductase. Catalyzes the reaction thioredoxin + NADP+ = thioredoxin disulfide + NADPH + H+. Putative selenoprotein with SECIS element in the 3'UTR detected using SECISearch
Glutaredoxin, also known as thioltransferase, is a small protein of approximately one hundred amino-acid residues
This enzyme phosphorylates InsP5 to form InsP6 (also known as phytate). InsP6 is involved in many processes such as mRNA export, nonhomologous end-joining, endocytosis and ion channel regulation.
type II DNA topoisomerase VI subunit A 2
Spo11/Topoisomerase 6A proteins initiate double strand break formation in meiotic recombination and are related to type II topoisomerase 6 subunit A of archaea
Contains a domain found in protein phosphatase 2C, as well as other proteins eg. pyruvate dehydrogenase (lipoamide)]-phosphatase and adenylate cyclase.
JmjC transcription factor domain-containing protein
Also has IMP dehydrogenase / GMP reductase domain; This family is involved in biosynthesis of guanosine nucleotide. Members of this family contain a TIM barrel structure; Alternative splicing variant 1
Pedicted member of the HSPB Group in the JmjN_JmjC Protein Family. ChromDB ID: JMJ20112; Alternative splicing variant 2
This gene has a cytochrome b5 family, heme-binding domain signature and profile. Cytochrome b5 is a membrane-bound hemoprotein which acts as an electron carrier for several membrane-bound oxygenases
putative protein required for cyt b6 assembly
This model contains an aminopeptidase I zinc metalloprotease (M18).
This model contains a Eukaryotic RNA recognition motif profile
ADP-glucose pyrophosphorylase Large subunit, isoform a.
glutamine synthetase, catalytic domain protein
Glutamine synthetase (GS) [1] is an enzyme that plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine: Glutamate + ATP + NH3 ->
glutamine synthetase, catalytic domain protein protein
Synonym: Parathyroid hormone-responsive B1 gene protein homolog
Myb-like DNA-binding domain containing. This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family; expressed
Has tRNA synthetases class I (E and Q), catalytic domain. Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only glutamyl and glutaminyl tRNA synthetases
CDKC (cyclin dependant kinase C)with a PTAIRE motif
DNA-directed RNA polymerase I polypeptide 2
cell division cycle protein 48-like protein, expessed
also known as Clp protease, ChloroP suggests 46 aa cTP, TargetP predicts chloroplast targeted but prediction is only 3 aa
Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12
candidate dolichyl-phosphate-sugar a-glycosyltransferase; has PFAM 05007: Mannosyl_trans Mannosyltransferase (PIG-M). PIG-M has a DXD motif
ribosomal L21 protein, chloroplast precursor
PF00829: Ribosomal prokaryotic L21 protein [also observed in eukaryotes]; ChloroP predicts 23 AA cTP; expressed
has Epimerase domain - short chain dehydrogenase; ChloroP predicts 79aa cTP; expressed
has 2 conserved domains: DHquinase_I and Shikimate / quinate 5-dehydrogenase; Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase
has PPR repeat. This repeat has no known function. It is about 35 amino acids long and found in up to 18 copies in some proteins. This family appears to be greatly expanded in plants
belongs to PRP38 family. Members of this family are related to the pre mRNA splicing factor PRP38 from yeast. Therefore all the members of this family could be involved in splicing
eukaryotic translation initiation factor 4E
lignostilbene-alpha beta-dioxygenase homolog
epoxycarotenoid cleavage enzyme/transferase
carotenoid cleavage dioxygenase, putative
Nucleotide excision repair endonuclease, Rad10 subunit
MAK16-like nucleolar RNA binding protein
demethylmenaquinone methyltransferase/aldolase
Likely fused protein, has two major domains Methyltransf_6 and KDPG/KHG-aldolase. This family includes the following members: 4-hydroxy-2-oxoglutarate aldolase (KHG-aldolase) Phospho-2-dehydro-3-deoxygluconate aldolase (KDPG-aldolase)
putative NAD dependent malate dehydrogenase (oxaloacetate decarboxylating),. No transit peptide predicted. Reaction: (S)-malate + NAD+ = pyruvate + CO2 + NADH
aaa-metalloprotease chloroplast precursor
membrane-anchored metalloprotease (M41 family) with a AAA domain; acts as a chaperone and a protease; involved on thylakoid biogenesis and PSII repair (PMID: 16126834); ChloroP and TargetP do not predict cTP but possible because start is modeled late - there are many alternative (earlier) starts
delta-aminolevulinic acid dehydratase chloroplast precursor
ribonuclease III domain-containing protein
Isoamyl_acetate_hydrolyzing esterase homolog
Has Yip1 domain; The Yip1 integral membrane domain contains four transmembrane alpha helices. The domain is characterised by the motifs DLYGP and GY
vacuolar protein sorting-associated protein
has MCM2 domain; MCM proteins are DNA-dependent ATPases required for the initiation of eukaryotic DNA replication. In eukaryotes there is a family of six proteins, MCM2 to MCM7
axonemal inner arm I1 intermediate chain dynein IC138
Predicted Bromodomain-containing protein. ChromDB ID: BRD20102
ATP-dependent Clp protease proteolytic subunit
expressed; conserved uncharacterized protein
Encodes a protein with single ERF domain
DUF667 - This family of proteins are highly conserved in eukaryotes. Some proteins in the family are annotated as transcription factors. However, there is currently no support for this in the literature. expressed
Predicted bromodomain-containing protein. ChromDB. ChromDB ID: GTE20104
Conserved oligomeric Golgi complex component 4
succinyl-CoA synthetase (GDP-forming), beta subunit; GTP + succinate + CoA = GDP + phosphate + succinyl-CoA; mitochondria precursor: TargetP predicted a 26 aa mTP
candidate monogalactosyldiacylglycerol synthase
H+-or Na+-translocating f-type, v-type and A-type ATPase superfamily
signal recognition particle 54 kDa protein (SRP54)
has hits to GATASE_TYPE_1, CTP_synth_N and GATase; expressed
putative pyruvate kinase, cytosolic. Localisation deduced by similarity search, no transit peptide predicted (ChloroP, TargetP, SignalP). Reaction: ATP + pyruvate = ADP + phosphoenolpyruvate
mitochondrial protein translocase family
outer membrane translocase (import) Tom40
Encodes a RWP-RK family transcription factor.
circadian rhythm control Timeless protein homolog
ATP-dependent Clp protease proteolytic subunit, plastid precursor
preprotein translocase Sec61 beta subunit
Magnesium-protoporyphyrin IX chelatase subunit chlI
Longevity-assurance protein, putative dihydroceramide synth. regulator
Endonuclease Mus81. Partner of Mms4 for interference-insensitive cross-over
Strongly Conserved WD repeat protein WD35
DNA-directed RNA polymerase III 62 kDa polypeptide (Subunit 3)
ChloroP predicts 51aa cTP whereas targeT predicts 31aa cTP
cupC8, conserved uncharacterized protein
candidate UDP-glucose:glycoprotein a-glucosyltransferase
dynein 18 kDa light chain, flagellar outer arm
prasinophyte specific chlorophyll a/b-binding protein, chloroplast precursor
ChloroP and TargetP predicts a 41 aa cTP
CAF1 component of the CCR4-NOT transcription complex
U3 small nucleolar RNA-associated protein 6 homolog
selenocysteine-specific elongation factor
Selenocystene-specific elongation factor. Translation factor necessary for the incorporation of selenocysteine into proteins
monovalent Cation:Proton antiporter-2 family
LHCI otherwise known as LHCA - Photosystem I associated chl a/b binding protein; type must be determined through phylogenetic analysis; ChloroP and TargetP predict 16aa cTP
fructose-bisphosphate aldolase, probably class I;, no TP predicted by ChloroP or TargetP
Histidinol-phosphate aminotransferase, chloroplast precursor
Encodes a protein with hydroxyproline-rich glycoprotein (HRGP) motifs and Patched domain found in Hedgehog receptors.
in Chlamy needed for flagellar outer row dynein assembly; expressed
Histone H3, core histone required for chromatin assembly and chromosome function. ChromDB ID: HTR20102
also similar to plant DEAD-box ATP-dependent RNA helicase 36
Has DnaJ domains and a Sec63 domain. DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction
Has S24-like peptidase domain; This signature is associated with serine peptidases belong to MEROPS peptidase families: S24 (LexA family, clan SF); S26A (signal peptidase I) and S26B (signalase)
Glutathione peroxidase. Closest DB hits are all GPX1, though this has not been confirmed through phylogeny
1-deoxy-D-xylulose-5-phosphate synthase, plastid precursor
conserved uncharacterized protein cupA44
contaims Cmc1 domain - Cephalosporin hydroxylase. Members of this family are about 220 amino acids long. The CmcI protein O85726_STRCL is presumed to represent the cephalosporin-7--hydroxylase
Predicted homolog Saccharomyces cerevisiae Spt16 protein, a subunit of the heterodimeric FACT complex (Spt16p-Pob3p), facilitates RNA Polymerase II transcription elongation through nucleosomes by destabilizing and then reassembling nucleosome structure ChromDB ID: GTC20101
as two domains: tRNA_bind which is found in prokaryotic methionyl-tRNA synthetases, prokaryotic phenylalanyl tRNA synthetases the yeast GU4 nucleic-binding protein (G4p1 or p42, ARC1), human tyrosyl-tRNA synthetase [1], and endothelial-monocyte activating polypeptide II. G4p1 binds specifically to tRNA form a complex with methionyl-tRNA synthetases. In human tyrosyl-tRNA synthetase this domain may direct tRNA to the active site of the enzyme. This domain may perform a common function in tRNA aminoacylation. Also has GTP_EFTU, Elongation factor Tu GTP binding domain. This domain contains a P-loop motif, also found in several other families such as Ras, Arf and Myosin_head. Elongation factor Tu consists of three structural domains, this plus two C-terminal beta barrel domains
expressed; semiconserved uncharacterized protein cupA45
peptidyl-prolyl cis-trans isomerase chloroplast precursor
likely, 40 kDa thylakoid lumen PPIase; 40 kDa thylakoid lumen rotamase; has domain for Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
Cytosolic 80S ribosomal protein L11; Cytosolic 60S large ribosomal subunit protein L11 - component of cytosolic 80S ribosome and 60S large subunit; targetP does not predict mTP
KH_1, The K homology (KH) domain was first identified in the human heterogeneous nuclear ribonucleoprotein (hnRNP) K
Has domain for histone-like transcription factor (CBF/NF-Y) and archaeal histone. This family includes archaebacterial histones and histone like transcription factors from eukaryotes
glutamyl-tRNA amidotransferase, subunitA
inner membrane translocase (import) Tim17
now transferred to; acetyl-CoA + H2O + oxaloacetate = citrate + CoA; MitoProt predicts a 29 aa mTP
signal recognition particle SRP43 protein, chloroplast precursor
Has SAP and ZF domains. The SAP motif is a 35-residue motif, which has been named after SAF-A/B, Acinus and PIAS, three proteins known to contain it
Involved in molybdenum cofactor biosynthesis.
conserved in RCC299, CCMP1545, Otauri and CCE9901. Contains a pfam domain for a conserved but hypothetical ATP binding domain PF03029.7. conserved uncharacterized protein CUPB009
AP-2 complex subunit beta-1 (Beta-adaptin)
Putatively; TGS is also known as PRIP-interacting protein with methyltransferase motif (PIMT) or nuclear receptor coactivator 6-interacting protein; expressed
This gene has both Cap-gly and AAA domains (2 AAA domains); Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network. The conserved motif in this gene model, CAP-Gly, has been identified in a number of CAPs
also known as Proteasome subunit alpha type-6, 20S proteasome alpha subunit F-2, Proteasome component 2B
Contains NOP5NT, NOSIC and NOP domains; NOP is a putative snoRNA binding domain, NOP5NT is the N terminal domain found in RNA-binding proteins of the NOP5 family; expressed
Rad50 pairs with Mre11 (and Xrs2/NBS1 in animals, fungi) to repair double strand breaks. This complex functions in DNA repair, telomere maintenance, and meiotic recombination
pfam 00560: LRR_1 Leucine-rich Repeat (LRR) protein [Function unkown]
u-box domain/leucine-rich repeat protein
pfam 00141: Peroxidase; see PROSITE [PS50873]
pfam 04564: U-box domain related to the Ring finger pfam00097 but lacks the zinc binding residues; pfam 00560: LRR_1 Leucine Rich Repeat (LRR) protein [Function unkown]
Encodes a protein with hydroxyproline-rich glycoprotein (HRGP) motifs
Putative protein with hydroxyproline-rich glycoprotein (HRGP) motifs and TPR motifs
regulator of chromosome condensation, RCC1
Contains regulator of chromosome condensation (RCC1) signatures The regulator of chromosome condensation (RCC1) [1] is a eukaryotic protein which binds to chromatin and interacts with ran, a nuclear GTP-binding protein (see), to promote the loss of bound GDP and the uptake of fresh GTP, thus acting as a guanine-nucleotide dissociation stimulator (GDS) [2]
Contains the Pfam domain FKBP_C FKBP-type peptidyl-prolyl cis-trans isomerase, also known as Peptidylprolyl cis-trans isomerases in vertebrates, are receptors for the two immunosuppressants, FK506 and rapamycin
Contains Pfam domain UPF0187 (uncharacterised protein family); putative uncharacterized protein
Conatins the Pfam domain hydrolase The haloacid dehalogenase-like hydrolase family are structurally different from the alpha/ beta hydrolase family (Abhydrolase_1)
Contains presumed diacylglycerol kinase catalytic domain Diacylglycerol (DAG) is a second messenger that acts as a protein kinase C activator
Contains a protein kinase domain Eukaryotic protein kinases PUBMED:12734000, PUBMED:7768349, PUBMED:1835513, PUBMED:1956325, PUBMED:3291115 are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases
monovalent Cation:Proton antiporter-1 family
Contains a NUDIX domain This family is a member of the NUDIX superfamily clan. putative uncharacterized proteins
Contains an ATP cone domain, a Ribonuc_red_lgN domain (Ribonucleotide reductase, all-alpha domain), and a Ribonuc_red_lgC domain (Ribonucleotide reductase, barrel domain)
encodes a protein with hydroxyproline-rich glycoprotein motifs
Contains the Pfam domain Band_7, also known as SPFH domain / Band 7 family and SPFH, Band 7 or PHB domain The band 7 protein is an integral membrane protein which is thought to regulate cation conductance
Contains WD40 repeat region (WD domain, G-beta repeat) WD-40 repeats (also known as WD or beta-transducin repeats) are short 40 amino acid motifs, often terminating in a Trp-Asp (W-D) dipeptide
Contains AlaDh_PNT_N (Alanine dehydrogenase/PNT, N-terminal domain) and PNTB (NAD(P) transhydrogenase beta subunit)domains
Contains DEAD (DEAD/DEAH box helicase), Helicase_C (Helicase conserved C-terminal), and DNA_pol_A (DNA polymerase family A or DNA nucleotidyltransferase) domains Members of the DEAD/DEAH box helicase family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression. The Helicase conserved C-terminal domain, which defines this group of proteins, is found in a wide variety of helicases and helicase related proteins. It may be that this is not an autonomously folding unit, but an integral part of the helicase. The eukaryotic translation initiation factor 4A (eIF4A) is a member of the DEA(D/H)-box RNA helicase family This is a diverse group of proteins that couples an ATPase activity to RNA binding and unwinding. The structure of the carboxyl-terminal domain of eIF4A has been determined to 1.75 A resolution
Pyruvate phosphate dikinase. Cytosolic; PPDK