Nicoliella spurrieriana strain SGEP1_A5 plasmid p1unnamed, complete sequence.
Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae; Nicoliella.
Apilactobacillus apisilvae sp. nov., Nicolia spurrieriana gen. nov. sp. nov., Bombilactobacillus folatiphilus sp. nov. and Bombilactobacillus thymidiniphilus sp. nov., four new lactic acid bacterial isolates from stingless bees Tetragonula carbonaria and Austroplebeia australis
Submitted (11-MAR-2022) Wine Science, The University of Adelaide, PMB 1, Glen Osmond, South Australia 5064, Australia
REFSEQ INFORMATION: The reference sequence is identical to\nCP093360.1.\nThe annotation was added by the NCBI Prokaryotic Genome Annotation\nPipeline (PGAP). Information about PGAP can be found here:\nhttps://www.ncbi.nlm.nih.gov/genome/annotation_prok/\n\n##Genome-Assembly-Data-START##\nAssembly Date :: NOV-2020\nAssembly Method :: Smrtlink v. 9.0\nGenome Representation :: Full\nExpected Final Version :: Yes\nGenome Coverage :: 6375x\nSequencing Technology :: PacBio Sequel II\n##Genome-Assembly-Data-END##\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: NCBI RefSeq\nAnnotation Date :: 04/16/2023 14:39:25\nAnnotation Pipeline :: NCBI Prokaryotic Genome\n Annotation Pipeline (PGAP)\nAnnotation Method :: Best-placed reference protein\n set; GeneMarkS-2+\nAnnotation Software revision :: 6.5\nFeatures Annotated :: Gene; CDS; rRNA; tRNA; ncRNA\nGenes (total) :: 1,732\nCDSs (total) :: 1,650\nGenes (coding) :: 1,634\nCDSs (with protein) :: 1,634\nGenes (RNA) :: 82\nrRNAs :: 5, 5, 5 (5S, 16S, 23S)\ncomplete rRNAs :: 5, 5, 5 (5S, 16S, 23S)\ntRNAs :: 64\nncRNAs :: 3\nPseudo Genes (total) :: 16\nCDSs (without protein) :: 16\nPseudo Genes (ambiguous residues) :: 0 of 16\nPseudo Genes (frameshifted) :: 6 of 16\nPseudo Genes (incomplete) :: 5 of 16\nPseudo Genes (internal stop) :: 7 of 16\nPseudo Genes (multiple problems) :: 2 of 16\nCRISPR Arrays :: 1\n##Genome-Annotation-Data-END##\nCOMPLETENESS: full length.
COORDINATES: similar to AA sequence:RefSeq:WP_014215854.1
GO:0005886 - plasma membrane [Evidence IEA]
Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: ab initio prediction:GeneMarkS-2+
Derived by automated computational analysis using gene prediction method: GeneMarkS-2+.
COORDINATES: protein motif:HMM:NF019310.2
COORDINATES: protein motif:HMM:NF024853.2
COORDINATES: similar to AA sequence:RefSeq:WP_005685364.1
GO:0015658 - branched-chain amino acid transmembrane transporter activity [Evidence IEA]
GO:0015803 - branched-chain amino acid transport [Evidence IEA]
branched-chain amino acid transport system II carrier protein
COORDINATES: similar to AA sequence:RefSeq:WP_003691561.1
COORDINATES: similar to AA sequence:RefSeq:WP_003639755.1
GO:0016491 - oxidoreductase activity [Evidence IEA]
COORDINATES: protein motif:HMM:NF019846.2
COORDINATES: similar to AA sequence:RefSeq:WP_007126061.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]
GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]
metalloregulator ArsR/SmtB family transcription factor
COORDINATES: protein motif:HMM:NF024919.2
COORDINATES: similar to AA sequence:RefSeq:WP_008858185.1
GO:0008902 - hydroxymethylpyrimidine kinase activity [Evidence IEA]; GO:0008972 - phosphomethylpyrimidine kinase activity [Evidence IEA]
GO:0009228 - thiamine biosynthetic process [Evidence IEA]
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
COORDINATES: similar to AA sequence:RefSeq:WP_010625328.1
COORDINATES: similar to AA sequence:RefSeq:WP_006500654.1
GO:0008081 - phosphoric diester hydrolase activity [Evidence IEA]
GO:0006629 - lipid metabolic process [Evidence IEA]
glycerophosphodiester phosphodiesterase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_004563412.1
ABC transporter substrate-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_003551069.1
GO:0008643 - carbohydrate transport [Evidence IEA]; GO:0055085 - transmembrane transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_002826040.1
GO:0140359 - ABC-type transporter activity [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_014939182.1
GO:0140359 - ABC-type transporter activity [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA]; GO:0016887 - ATP hydrolysis activity [Evidence IEA]; GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_017867460.1
GO:0005215 - transporter activity [Evidence IEA]
GO:0009228 - thiamine biosynthetic process [Evidence IEA]; GO:0006810 - transport [Evidence IEA]
energy coupling factor transporter S component ThiW
COORDINATES: nucleotide motif:Rfam:14.4:RF00059
TPP riboswitch; Derived by automated computational analysis using gene prediction method: cmsearch.
COORDINATES: similar to AA sequence:RefSeq:WP_003136757.1
COORDINATES: protein motif:HMM:NF006365.0
GO:0016787 - hydrolase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_016618437.1
GO:0022857 - transmembrane transporter activity [Evidence IEA]
GO:0055085 - transmembrane transport [Evidence IEA]
COORDINATES: protein motif:HMM:NF024867.2
COORDINATES: similar to AA sequence:RefSeq:WP_008856168.1
COORDINATES: similar to AA sequence:RefSeq:WP_010631755.1
COORDINATES: similar to AA sequence:RefSeq:WP_010018191.1
COORDINATES: protein motif:HMM:NF015509.2
COORDINATES: protein motif:HMM:NF016174.2
COORDINATES: similar to AA sequence:RefSeq:WP_017260659.1
GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; GO:0016491 - oxidoreductase activity [Evidence IEA]
COORDINATES: protein motif:HMM:NF024637.2
COORDINATES: similar to AA sequence:RefSeq:WP_010690186.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0016887 - ATP hydrolysis activity [Evidence IEA]
ATP-dependent Clp protease ATP-binding subunit
COORDINATES: similar to AA sequence:RefSeq:WP_003685663.1
COORDINATES: similar to AA sequence:RefSeq:WP_017261657.1
COORDINATES: protein motif:HMM:NF015925.2
GO:0004497 - monooxygenase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_003639995.1
COORDINATES: similar to AA sequence:RefSeq:WP_004049248.1
amino acid ABC transporter ATP-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_003658920.1
amino acid ABC transporter substrate-binding protein/permease
COORDINATES: similar to AA sequence:RefSeq:WP_003634249.1
GO:0030170 - pyridoxal phosphate binding [Evidence IEA]
GO:0009058 - biosynthetic process [Evidence IEA]
aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme
TetR/AcrR family transcriptional regulator
COORDINATES: similar to AA sequence:RefSeq:WP_002828354.1
COORDINATES: protein motif:HMM:NF018604.2
GO:0016020 - membrane [Evidence IEA]; GO:0005886 - plasma membrane [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_013727674.1
GO:0004372 - glycine hydroxymethyltransferase activity [Evidence IEA]; GO:0030170 - pyridoxal phosphate binding [Evidence IEA]; GO:0070905 - serine binding [Evidence IEA]; GO:0008270 - zinc ion binding [Evidence IEA]
GO:0019264 - glycine biosynthetic process from serine [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020089961.1
GO:0005525 - GTP binding [Evidence IEA]; GO:0003924 - GTPase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_003557876.1
zinc-dependent alcohol dehydrogenase family protein
COORDINATES: protein motif:HMM:NF012415.2
COORDINATES: similar to AA sequence:RefSeq:WP_004562841.1
COORDINATES: protein motif:HMM:NF014477.2
COORDINATES: similar to AA sequence:RefSeq:WP_006738455.1
COORDINATES: similar to AA sequence:RefSeq:WP_016387647.1
COORDINATES: similar to AA sequence:RefSeq:WP_003567714.1
COORDINATES: similar to AA sequence:RefSeq:WP_010620619.1
COORDINATES: similar to AA sequence:RefSeq:WP_014082121.1
COORDINATES: similar to AA sequence:RefSeq:WP_003559234.1
incomplete; partial in the middle of a contig; missing N-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: protein motif:HMM:NF023802.2
COORDINATES: protein motif:HMM:NF039855.1
COORDINATES: similar to AA sequence:RefSeq:WP_011254617.1
GO:0009252 - peptidoglycan biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_003131760.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0003908 - methylated-DNA-[protein]-cysteine S-methyltransferase activity [Evidence IEA]
methylated-DNA--[protein]-cysteine S-methyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_006584660.1
COORDINATES: similar to AA sequence:RefSeq:WP_010689183.1
COORDINATES: nucleotide motif:Rfam:14.4:RF00230
T-box leader; Derived by automated computational analysis using gene prediction method: cmsearch.
COORDINATES: similar to AA sequence:RefSeq:WP_011666828.1
COORDINATES: similar to AA sequence:RefSeq:WP_003552225.1
GO:0055052 - ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [Evidence IEA]
peptide ABC transporter substrate-binding protein
COORDINATES: protein motif:HMM:NF024230.2
threonine/serine exporter family protein
COORDINATES: protein motif:HMM:NF018448.2
COORDINATES: similar to AA sequence:RefSeq:WP_010347599.1
COORDINATES: protein motif:HMM:NF012931.2
GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]
GO:0005975 - carbohydrate metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_006830160.1
COORDINATES: protein motif:HMM:NF036540.2
COORDINATES: similar to AA sequence:RefSeq:WP_014081421.1
GO:0004735 - pyrroline-5-carboxylate reductase activity [Evidence IEA]
GO:0006561 - proline biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_006887391.1
GO:0015144 - carbohydrate transmembrane transporter activity [Evidence IEA]
GO:0034219 - carbohydrate transmembrane transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010019189.1
GO:0008998 - ribonucleoside-triphosphate reductase activity [Evidence IEA]
GO:0006260 - DNA replication [Evidence IEA]
anaerobic ribonucleoside-triphosphate reductase
COORDINATES: similar to AA sequence:RefSeq:WP_012391514.1
GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]
GO:0009265 - 2'-deoxyribonucleotide biosynthetic process [Evidence IEA]; GO:0051353 - positive regulation of oxidoreductase activity [Evidence IEA]
anaerobic ribonucleoside-triphosphate reductase activating protein
COORDINATES: similar to AA sequence:RefSeq:WP_003645724.1
COORDINATES: similar to AA sequence:RefSeq:WP_015639781.1
COORDINATES: similar to AA sequence:RefSeq:WP_010622675.1
incomplete; partial in the middle of a contig; missing C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_002818713.1
COORDINATES: similar to AA sequence:RefSeq:WP_003716111.1
PLP-dependent aminotransferase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_010493046.1
sulfite exporter TauE/SafE family protein
COORDINATES: similar to AA sequence:RefSeq:WP_020281477.1
GO:0003984 - acetolactate synthase activity [Evidence IEA]; GO:0000287 - magnesium ion binding [Evidence IEA]; GO:0030976 - thiamine pyrophosphate binding [Evidence IEA]
GO:0034077 - butanediol metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010020910.1
GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_003147286.1
GO:0034257 - nicotinamide riboside transmembrane transporter activity [Evidence IEA]
GO:0034258 - nicotinamide riboside transport [Evidence IEA]
COORDINATES: protein motif:HMM:NF012798.2
GO:0015074 - DNA integration [Evidence IEA]; GO:0006310 - DNA recombination [Evidence IEA]
COORDINATES: protein motif:HMM:NF026010.2
COORDINATES: protein motif:HMM:NF033516.0
GO:0004803 - transposase activity [Evidence IEA]
COORDINATES: protein motif:HMM:NF024908.2
GO:0003677 - DNA binding [Evidence IEA]; GO:0004803 - transposase activity [Evidence IEA]
GO:0006313 - transposition, DNA-mediated [Evidence IEA]
COORDINATES: protein motif:HMM:NF026008.2
Arm DNA-binding domain-containing protein
COORDINATES: protein motif:HMM:NF025825.2
COORDINATES: similar to AA sequence:RefSeq:WP_014919374.1
GO:0009007 - site-specific DNA-methyltransferase (adenine-specific) activity [Evidence IEA]
GO:0032775 - DNA methylation on adenine [Evidence IEA]
COORDINATES: protein motif:HMM:NF024700.2
COORDINATES: similar to AA sequence:RefSeq:WP_002324930.1
helix-turn-helix transcriptional regulator
COORDINATES: protein motif:HMM:NF024835.2
COORDINATES: similar to AA sequence:RefSeq:WP_086558186.1
frameshifted; internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_010747640.1
COORDINATES: similar to AA sequence:RefSeq:WP_003665509.1
COORDINATES: similar to AA sequence:RefSeq:WP_020280805.1
GO:0015385 - sodium:proton antiporter activity [Evidence IEA]
GO:1902600 - proton transmembrane transport [Evidence IEA]; GO:0006814 - sodium ion transport [Evidence IEA]
COORDINATES: protein motif:HMM:NF019604.2
COORDINATES: protein motif:HMM:NF012345.2
Members of this family of hydrolases with an active site Cys residue belong to MEROPS family C26.; Members of this family of hydrolases with an active site Cys residue belong to MEROPS family C26; Derived by automated computational analysis using gene prediction method: Protein Homology.
gamma-glutamyl-gamma-aminobutyrate hydrolase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_004466717.1
COORDINATES: similar to AA sequence:RefSeq:WP_002828291.1
COORDINATES: similar to AA sequence:RefSeq:WP_020281263.1
COORDINATES: protein motif:HMM:NF013309.2
GO:0005576 - extracellular region [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020280862.1
COORDINATES: similar to AA sequence:RefSeq:WP_003557265.1
COORDINATES: similar to AA sequence:RefSeq:WP_013728553.1
COORDINATES: similar to AA sequence:RefSeq:WP_010023000.1
COORDINATES: similar to AA sequence:RefSeq:WP_020089366.1
GO:0043295 - glutathione binding [Evidence IEA]; GO:0004602 - glutathione peroxidase activity [Evidence IEA]
COORDINATES: protein motif:HMM:NF016214.2
COORDINATES: similar to AA sequence:RefSeq:WP_003564445.1
COORDINATES: similar to AA sequence:RefSeq:WP_003556583.1
GO:0004413 - homoserine kinase activity [Evidence IEA]
GO:0009088 - threonine biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_013729065.1
GO:0004795 - threonine synthase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008690782.1
GO:0004412 - homoserine dehydrogenase activity [Evidence IEA]; GO:0050661 - NADP binding [Evidence IEA]
GO:0006520 - amino acid metabolic process [Evidence IEA]
COORDINATES: protein motif:HMM:TIGR00657.1
GO:0004072 - aspartate kinase activity [Evidence IEA]
COORDINATES: protein motif:HMM:NF014296.2
GO:0004489 - methylenetetrahydrofolate reductase (NAD(P)H) activity [Evidence IEA]
GO:0006555 - methionine metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_003559349.1
COORDINATES: similar to AA sequence:RefSeq:WP_010691673.1
GO:0009055 - electron transfer activity [Evidence IEA]; GO:0010181 - FMN binding [Evidence IEA]; GO:0008753 - NADPH dehydrogenase (quinone) activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008856443.1
GO:0019152 - acetoin dehydrogenase activity [Evidence IEA]
GO:0045150 - acetoin catabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_013642381.1
COORDINATES: similar to AA sequence:RefSeq:WP_006846000.1
COORDINATES: similar to AA sequence:RefSeq:WP_010619096.1
GO:0003871 - 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity [Evidence IEA]; GO:0008270 - zinc ion binding [Evidence IEA]
GO:0008652 - amino acid biosynthetic process [Evidence IEA]; GO:0009086 - methionine biosynthetic process [Evidence IEA]
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_020280638.1
GO:0009086 - methionine biosynthetic process [Evidence IEA]
methylenetetrahydrofolate reductase [NAD(P)H]
COORDINATES: similar to AA sequence:RefSeq:WP_017260647.1
COORDINATES: similar to AA sequence:RefSeq:WP_013355767.1
COORDINATES: protein motif:HMM:NF027074.2
type II toxin-antitoxin system YafQ family toxin
COORDINATES: protein motif:HMM:NF016136.2
type II toxin-antitoxin system RelB/DinJ family antitoxin
COORDINATES: similar to AA sequence:RefSeq:WP_011679074.1
ATP-binding cassette domain-containing protein
COORDINATES: protein motif:HMM:NF013677.2
COORDINATES: similar to AA sequence:RefSeq:WP_011676164.1
COORDINATES: similar to AA sequence:RefSeq:WP_011676163.1
helix-turn-helix domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_003716192.1
COORDINATES: similar to AA sequence:RefSeq:WP_017867625.1
O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase
COORDINATES: similar to AA sequence:RefSeq:WP_003677786.1
GO:0019346 - transsulfuration [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_017367031.1
aminotransferase class V-fold PLP-dependent enzyme
COORDINATES: similar to AA sequence:RefSeq:WP_017867528.1
COORDINATES: similar to AA sequence:RefSeq:WP_005917436.1
COORDINATES: similar to AA sequence:RefSeq:WP_015825935.1
COORDINATES: protein motif:HMM:TIGR01252.1
GO:0047605 - acetolactate decarboxylase activity [Evidence IEA]
GO:0045151 - acetoin biosynthetic process [Evidence IEA]; GO:0006113 - fermentation [Evidence IEA]
COORDINATES: protein motif:HMM:NF025636.2
COORDINATES: similar to AA sequence:RefSeq:WP_008858326.1
COORDINATES: similar to AA sequence:RefSeq:WP_013727063.1
COORDINATES: similar to AA sequence:RefSeq:WP_006499760.1
GO:0004401 - histidinol-phosphatase activity [Evidence IEA]
GO:0000105 - histidine biosynthetic process [Evidence IEA]
COORDINATES: protein motif:HMM:NF024785.2
ATP phosphoribosyltransferase regulatory subunit
COORDINATES: similar to AA sequence:RefSeq:WP_006555304.1
GO:0003879 - ATP phosphoribosyltransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011101827.1
GO:0004399 - histidinol dehydrogenase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_003644682.1
GO:0004424 - imidazoleglycerol-phosphate dehydratase activity [Evidence IEA]
imidazoleglycerol-phosphate dehydratase HisB
COORDINATES: similar to AA sequence:RefSeq:WP_006499765.1
GO:0016884 - carbon-nitrogen ligase activity, with glutamine as amido-N-donor [Evidence IEA]; GO:0000107 - imidazoleglycerol-phosphate synthase activity [Evidence IEA]
imidazole glycerol phosphate synthase subunit HisH
COORDINATES: similar to AA sequence:RefSeq:WP_005387491.1
COORDINATES: similar to AA sequence:RefSeq:WP_016364227.1
GO:0000107 - imidazoleglycerol-phosphate synthase activity [Evidence IEA]
imidazole glycerol phosphate synthase subunit HisF
COORDINATES: similar to AA sequence:RefSeq:WP_003646591.1
GO:0004635 - phosphoribosyl-AMP cyclohydrolase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004694199.1
GO:0004636 - phosphoribosyl-ATP diphosphatase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_006499770.1
GO:0004400 - histidinol-phosphate transaminase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_013726871.1
GO:0015171 - amino acid transmembrane transporter activity [Evidence IEA]
GO:0006865 - amino acid transport [Evidence IEA]; GO:0055085 - transmembrane transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_005724613.1
COORDINATES: similar to AA sequence:RefSeq:WP_013525629.1
COORDINATES: similar to AA sequence:RefSeq:WP_015528174.1
COORDINATES: protein motif:HMM:NF012382.2
COORDINATES: similar to AA sequence:RefSeq:WP_019394333.1
COORDINATES: protein motif:HMM:NF023112.2
COORDINATES: similar to AA sequence:RefSeq:WP_010021043.1
COORDINATES: protein motif:HMM:NF024110.2
COORDINATES: protein motif:HMM:NF012311.2
GO:0008236 - serine-type peptidase activity [Evidence IEA]
COORDINATES: protein motif:HMM:NF025025.2
COORDINATES: similar to AA sequence:RefSeq:WP_003684810.1
COORDINATES: similar to AA sequence:RefSeq:WP_010631119.1
isocitrate lyase/PEP mutase family protein
COORDINATES: protein motif:HMM:NF025091.2
isocitrate lyase/phosphoenolpyruvate mutase family protein
COORDINATES: protein motif:HMM:NF017946.2
COORDINATES: protein motif:HMM:NF012235.2
COORDINATES: similar to AA sequence:RefSeq:WP_003552925.1
GO:0016853 - isomerase activity [Evidence IEA]
PhzF family phenazine biosynthesis protein
COORDINATES: protein motif:HMM:NF012607.2
COORDINATES: similar to AA sequence:RefSeq:WP_003572225.1
COORDINATES: protein motif:HMM:NF015553.2
COORDINATES: similar to AA sequence:RefSeq:WP_003561572.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0000156 - phosphorelay response regulator activity [Evidence IEA]; GO:0004673 - protein histidine kinase activity [Evidence IEA]
GO:0007165 - signal transduction [Evidence IEA]
HAMP domain-containing sensor histidine kinase
COORDINATES: similar to AA sequence:RefSeq:WP_008212116.1
GO:0000160 - phosphorelay signal transduction system [Evidence IEA]; GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_003636575.1
COORDINATES: similar to AA sequence:RefSeq:WP_003563806.1
COORDINATES: protein motif:HMM:NF014724.2
COORDINATES: similar to AA sequence:RefSeq:WP_004166700.1
GO:0005575 - cellular_component [Evidence IEA]
GO:0004520 - endodeoxyribonuclease activity [Evidence IEA]
GO:0043571 - maintenance of CRISPR repeat elements [Evidence IEA]
Cas9, originally named Csn1, is the large, multifunctional signature protein of type II CRISPR/Cas systems. It is well known even to general audiences because its RNA-guided endonuclease activity has made it a popular tool for custom editing of eukaryotic genomes.; Cas9, originally named Csn1, is the large, multifunctional signature protein of type II CRISPR/Cas systems. It is well known even to general audiences because its RNA-guided endonuclease activity has made it a popular tool for custom editing of eukaryotic genomes; Derived by automated computational analysis using gene prediction method: Protein Homology.
type II CRISPR RNA-guided endonuclease Cas9
COORDINATES: similar to AA sequence:RefSeq:WP_003648676.1
GO:0004520 - endodeoxyribonuclease activity [Evidence IEA]; GO:0046872 - metal ion binding [Evidence IEA]; GO:0003676 - nucleic acid binding [Evidence IEA]
GO:0051607 - defense response to virus [Evidence IEA]; GO:0043571 - maintenance of CRISPR repeat elements [Evidence IEA]
type II CRISPR-associated endonuclease Cas1
COORDINATES: similar to AA sequence:RefSeq:WP_013728650.1
GO:0004521 - endoribonuclease activity [Evidence IEA]
COORDINATES: protein motif:HMM:TIGR01866.1
GO:0003674 - molecular_function [Evidence IEA]
type II-A CRISPR-associated protein Csn2
Derived by automated computational analysis using gene prediction method: tRNAscan-SE.
COORDINATES: similar to AA sequence:RefSeq:WP_013728524.1
COORDINATES: protein motif:HMM:NF019618.2
COORDINATES: protein motif:HMM:NF024743.2
COORDINATES: similar to AA sequence:RefSeq:WP_003678050.1
GO:0008080 - N-acetyltransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_014214902.1
COORDINATES: similar to AA sequence:RefSeq:WP_013727629.1
COORDINATES: similar to AA sequence:RefSeq:WP_019773766.1
COORDINATES: similar to AA sequence:RefSeq:WP_014568157.1
COORDINATES: similar to AA sequence:RefSeq:WP_020281650.1
GO:0003849 - 3-deoxy-7-phosphoheptulonate synthase activity [Evidence IEA]
GO:0009423 - chorismate biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008213457.1
GO:0003856 - 3-dehydroquinate synthase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011668737.1
COORDINATES: protein motif:HMM:NF012993.2
carbon-nitrogen hydrolase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_014325017.1
GO:0050334 - thiaminase activity [Evidence IEA]
GO:0006772 - thiamine metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_016176123.1
COORDINATES: similar to AA sequence:RefSeq:WP_010007554.1
GO:0004789 - thiamine-phosphate diphosphorylase activity [Evidence IEA]
COORDINATES: protein motif:HMM:NF006830.0
GO:0004417 - hydroxyethylthiazole kinase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_002817964.1
COORDINATES: protein motif:HMM:NF014841.2
COORDINATES: similar to AA sequence:RefSeq:WP_006500360.1
COORDINATES: similar to AA sequence:RefSeq:WP_010631809.1
COORDINATES: similar to AA sequence:RefSeq:WP_003558896.1
COORDINATES: similar to AA sequence:RefSeq:WP_004466277.1
COORDINATES: similar to AA sequence:RefSeq:WP_016372253.1
COORDINATES: similar to AA sequence:RefSeq:WP_003669421.1
COORDINATES: similar to AA sequence:RefSeq:WP_010624880.1
COORDINATES: similar to AA sequence:RefSeq:WP_010619311.1
GO:0004834 - tryptophan synthase activity [Evidence IEA]
GO:0000162 - tryptophan biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_003645136.1
COORDINATES: similar to AA sequence:RefSeq:WP_003633628.1
COORDINATES: similar to AA sequence:RefSeq:WP_003633627.1
GO:0004425 - indole-3-glycerol-phosphate synthase activity [Evidence IEA]
GO:0006568 - tryptophan metabolic process [Evidence IEA]
indole-3-glycerol phosphate synthase TrpC
COORDINATES: similar to AA sequence:RefSeq:WP_010018567.1
GO:0004048 - anthranilate phosphoribosyltransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008213454.1
GO:0046820 - 4-amino-4-deoxychorismate synthase activity [Evidence IEA]; GO:0004049 - anthranilate synthase activity [Evidence IEA]
aminodeoxychorismate/anthranilate synthase component II
COORDINATES: protein motif:HMM:NF012640.2
GO:0046872 - metal ion binding [Evidence IEA]
anthranilate synthase component I family protein
COORDINATES: similar to AA sequence:RefSeq:WP_019251926.1
GO:0050661 - NADP binding [Evidence IEA]; GO:0004764 - shikimate 3-dehydrogenase (NADP+) activity [Evidence IEA]
GO:0019632 - shikimate metabolic process [Evidence IEA]
COORDINATES: protein motif:HMM:TIGR01093.1
GO:0003855 - 3-dehydroquinate dehydratase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_003644493.1
GO:0004107 - chorismate synthase activity [Evidence IEA]
GO:0009073 - aromatic amino acid family biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008856458.1
GO:0003866 - 3-phosphoshikimate 1-carboxyvinyltransferase activity [Evidence IEA]
3-phosphoshikimate 1-carboxyvinyltransferase
COORDINATES: protein motif:HMM:NF014234.2
COORDINATES: protein motif:HMM:NF013375.2
GO:0005524 - ATP binding [Evidence IEA]; GO:0000287 - magnesium ion binding [Evidence IEA]; GO:0004765 - shikimate kinase activity [Evidence IEA]
GO:0008652 - amino acid biosynthetic process [Evidence IEA]; GO:0009073 - aromatic amino acid family biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_003557964.1
transporter substrate-binding domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_012391160.1
GO:0006865 - amino acid transport [Evidence IEA]
COORDINATES: protein motif:HMM:NF012738.2
GO:0055052 - ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [Evidence IEA]; GO:0005886 - plasma membrane [Evidence IEA]
GO:0015837 - amine transport [Evidence IEA]
The N-terminal region of this protein, as described by TIGR01726, is a three transmembrane segment that identifies a subfamily of ABC transporter permease subunits, which specificities that include histidine, arginine, glutamine, glutamate, L-cystine (sic), the opines (in Agrobacterium) octopine and nopaline, etc.; The N-terminal region of this protein, as described by TIGR01726, is a three transmembrane segment that identifies a subfamily of ABC transporter permease subunits, which specificities that include histidine, arginine, glutamine, glutamate, L-cystine (sic), the opines (in Agrobacterium) octopine and nopaline, etc.; The N-terminal region of this protein, as described by TIGR01726, is a three transmembrane segment that identifies a subfamily of ABC transporter permease subunits, which specificities that include histidine, arginine, glutamine, glutamate, L-cystine (sic), the opines (in Agrobacterium) octopine and nopaline, etc; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_003557958.1
COORDINATES: protein motif:HMM:NF013381.2
GO:0004853 - uroporphyrinogen decarboxylase activity [Evidence IEA]
GO:0006779 - porphyrin-containing compound biosynthetic process [Evidence IEA]
uroporphyrinogen decarboxylase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_009552573.1
heavy metal-binding domain-containing protein
COORDINATES: protein motif:HMM:NF017970.2
COORDINATES: protein motif:HMM:NF012792.2
COORDINATES: similar to AA sequence:RefSeq:WP_004840114.1
COORDINATES: protein motif:HMM:NF024803.2
COORDINATES: similar to AA sequence:RefSeq:WP_018883297.1
COORDINATES: similar to AA sequence:RefSeq:WP_004466585.1
COORDINATES: similar to AA sequence:RefSeq:WP_013238700.1
aspartate aminotransferase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_010620409.1
COORDINATES: similar to AA sequence:RefSeq:WP_015472983.1
COORDINATES: similar to AA sequence:RefSeq:WP_007955530.1
GO:0004084 - branched-chain-amino-acid transaminase activity [Evidence IEA]
GO:0009081 - branched-chain amino acid metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010631588.1
COORDINATES: protein motif:HMM:NF024989.2
COORDINATES: protein motif:HMM:NF012312.2
COORDINATES: similar to AA sequence:RefSeq:WP_013974908.1
GO:0050131 - N-methyl-L-amino-acid oxidase activity [Evidence IEA]
COORDINATES: protein motif:HMM:NF019371.2
COORDINATES: similar to AA sequence:RefSeq:WP_008803092.1
COORDINATES: similar to AA sequence:RefSeq:WP_016181718.1
COORDINATES: similar to AA sequence:RefSeq:WP_007125045.1
COORDINATES: protein motif:HMM:NF015651.2
lysylphosphatidylglycerol synthase domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_018030040.1
GO:0016790 - thiolester hydrolase activity [Evidence IEA]
COORDINATES: protein motif:HMM:NF024811.2
COORDINATES: similar to AA sequence:RefSeq:WP_009167292.1
GO:0047112 - pyruvate oxidase activity [Evidence IEA]
GO:0009444 - pyruvate oxidation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010490256.1
type 1 glutamine amidotransferase domain-containing protein
COORDINATES: protein motif:HMM:NF013077.2
GO:0016491 - oxidoreductase activity [Evidence IEA]; GO:0016657 - oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor [Evidence IEA]