Kluyveromyces lactis strain NRRL Y-1140 chromosome F complete sequence.
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
Submitted (25-SEP-2017) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (09-SEP-2008) Genoscope - Centre National de Sequencage : BP 191 91006 EVRY cedex - FRANCE (E-mail : seqref@genoscope.cns.fr - Web : www.genoscope.cns.fr)
PROVISIONAL REFSEQ: This record has not yet been subject to final\nNCBI review. The reference sequence is identical to CR382126.\nThis is an updated version of the complete genome sequence. The\nKluyveromyces lactis sequence is made of 6 chromosomes (A to F).\nThe sequence was annotated by the Genolevures Consortium. For more\ninformation go to\nhttp://cbi.labri.fr/Genolevures.\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: INSDC submitter\nAnnotation Status :: Full annotation\nAnnotation Pipeline :: Eukaryotic Annotation Propagation Pipeline\n##Genome-Annotation-Data-END##
similar to uniprot|P36032 Saccharomyces cerevisiae YKL221W MCH2 Protein with similarity to mammalian monocarboxylate permeases which are involved in transport of monocarboxylic acids across the plasma membrane mutant is not deficient in monocarboxylate transport
similar to uniprot|Q06598 Saccharomyces cerevisiae YPR201W ARR3 Arsenite transporter of the plasma membrane required for resistance to arsenic compounds transcription is activated by Arr1p in the presence of arsenite
similar to uniprot|P40100 Saccharomyces cerevisiae YER185W Hypothetical ORF and to YGR213C uniprot|P53047 Saccharomyces cerevisiae YGR213C RTA1 involved in 7-aminocholesterol resistance
similar to uniprot|Q12235 Saccharomyces cerevisiae YLL055W Hypothetical ORF
weakly similar to uniprot|P39718 Saccharomyces cerevisiae YAL055W PEX22
similar to uniprot|P48581 Saccharomyces cerevisiae YOR368W RAD17 Checkpoint protein involved in the activation of the DNA damage and meiotic pachytene checkpoints with Mec3p and Ddc1p forms a clamp that is loaded onto partial duplex DNA homolog of human and S. pombe Rad1 and U. maydis Rec1 proteins
similar to uniprot|P48589 Saccharomyces cerevisiae YOR369C RPS12 Protein component of the small (40S) ribosomal subunit
weakly similar to uniprot|Q08886 Saccharomyces cerevisiae YOR371C GPB1 Proposed beta subunit of the heterotrimeric G protein that interacts with the receptor Grp1p has signaling role in response to nutrients involved in regulation of pseudohyphal growth through cAMP levels homolog of Gpb2p
weakly similar to uniprot|Q08887 Saccharomyces cerevisiae YOR372C NDD1 Transcriptional activator essential for nuclear division
weakly similar to uniprot|P32336 Saccharomyces cerevisiae YOR373W NUD1 Component of the spindle pole body outer plaque required for exit from mitosis
highly similar to uniprot|P46367 Saccharomyces cerevisiae YOR374W ALD4 Mitochondrial aldehyde dehydrogenase that utilizes NADP or NAD equally as coenzymes expression is glucose repressed
some similarities with uniprot|P27825 Saccharomyces cerevisiae YAL058W CNE1
similar to uniprot|P39715 Saccharomyces cerevisiae YAL059W ECM1 Protein of unknown function localized in the nucleoplasm and the nucleolus genetically interacts with MTR2 in 60S ribosomal protein subunit export
similar to uniprot|P39714 Saccharomyces cerevisiae YAL060W BDH1 NAD-dependent (2R 3R)-2 3-butanediol dehydrogenase
similar to uniprot|P39713 Saccharomyces cerevisiae YAL061W putative polyol dehydrogenase
highly similar to uniprot|P07262 Saccharomyces cerevisiae and to YAL062W uniprot|P39708 Saccharomyces cerevisiae, GDH3 NADP(+)-dependent glutamate dehydrogenase
some similarities with uniprot|Q12473 Saccharomyces cerevisiae YLL051C
weakly similar to uniprot|P53912 Saccharomyces cerevisiae or YLR460C uniprot|P54007 Saccharomyces cerevisiae YLR460C Hypothetical ORFs
similar to uniprot|Q02979 Saccharomyces cerevisiae YPL110C Hypothetical ORF
similar to uniprot|P00812 Saccharomyces cerevisiae YPL111W CAR1 Arginase
similar to uniprot|Q6B2A9 Saccharomyces cerevisiae YPL112C PEX25 Peripheral peroxisomal membrane peroxin required for the regulation of peroxisome size and maintenance recruits GTPase Rho1p to peroxisomes induced by oleate interacts with homologous protein Pex27p
similar to uniprot|Q74ZW6 Ashbya gossypii AGR228C and weakly similar to YOR194C uniprot|P32773 Saccharomyces cerevisiae TOA1 Transcription factor IIA large chain
some similarities with uniprot|Q08581 Saccharomyces cerevisiae YOR195W SLK19 Kinetochore-associated protein required for normal segregation of chromosomes in meiosis and mitosis
similar to uniprot|Q02961 Saccharomyces cerevisiae YPL113C Putative dehydrogenase
similar to uniprot|P32873 Saccharomyces cerevisiae YPL115C BEM3 Rho GTPase activating protein (RhoGAP) involved in control of the cytoskeleton organization
highly similar to uniprot|P32875 Saccharomyces cerevisiae YOR196C LIP5 Protein involved in biosynthesis of the coenzyme lipoic acid
similar to uniprot|Q02959 Saccharomyces cerevisiae YPL116W HOS3 Trichostatin A-insensitive homodimeric histone deacetylase (HDAC)
similar to uniprot|Q08601 Saccharomyces cerevisiae YOR197W MCA1 Putative cysteine protease similar to mammalian caspases
similar to uniprot|P38934 Saccharomyces cerevisiae YOR198C BFR1 Component of mRNP complexes associated with polyribosomes
highly similar to uniprot|P15496 Saccharomyces cerevisiae YPL117C IDI1 Isopentenyl diphosphate:dimethylallyl diphosphate isomerase
similar to uniprot|P25270 Saccharomyces cerevisiae YOR201C MRM1 Ribose methyltransferase that modifies a functionally critical nucleotide in mitochondrial 21S rRNA
highly similar to uniprot|P06633 Saccharomyces cerevisiae YOR202W HIS3 Imidazoleglycerol-phosphate dehydratase
similar to uniprot|Q02950 Saccharomyces cerevisiae YPL118W MRP51 Mitochondrial ribosomal protein of the large subunit MRP51
similar to uniprot|P48813 Saccharomyces cerevisiae YDR508C GNP1 High-affinity glutamine permease also transports Leu Ser Thr Cys Met and Asn
similar to uniprot|P06634 Saccharomyces cerevisiae YOR204W DED1 ATP-dependent DEAD (Asp-Glu-Ala-Asp)-box RNA helicase required for translation initiation of all yeast mRNAs
similar to uniprot|Q02939 Saccharomyces cerevisiae YPL122C TFB2 subunit of TFIIH and nucleotide excision repair factor 3 complexes
highly similar to uniprot|P22276 Saccharomyces cerevisiae YOR207C RET1 second-largest subunit of RNA polymerase III
similar to uniprot|P32489 Saccharomyces cerevisiae YPL121C MEI5 Meiosis specific protein involved in DMC1-dependent meiotic recombination
similar to uniprot|P39744 Saccharomyces cerevisiae YOR206W NOC2 Protein that forms a nucleolar complex with Mak21p that binds to 90S and 66S pre-ribosomes as well as a nuclear complex with Noc3p that binds to 66S pre- ribosomes both complexes mediate intranuclear transport of ribosomal precursors
similar to uniprot|Q08622 Saccharomyces cerevisiae YOR205C FMP38 The authentic non-tagged protein was localized to the mitochondria
similar to uniprot|Q02948 Saccharomyces cerevisiae YPL120W VPS30 Protein required for sorting and delivery of soluble hydrolases to the vacuole
highly similar to uniprot|P21524 Saccharomyces cerevisiae YER070W RNR1 Ribonucleotide-diphosphate reductase (RNR) and to YIL066C uniprot|P21672 Saccharomyces cerevisiae YIL066C RNR3 Ribonucleotide- diphosphate reductase (RNR), large subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits
similar to uniprot|P37292 Saccharomyces cerevisiae YBR263W SHM1 Serine hydroxymethyltransferase mitochondrial
similar to uniprot|P36019 Saccharomyces cerevisiae YNL093W YPT53 Involved in vacuolar protein sorting and endocytosis GTP-binding protein of the rab family
weakly similar to uniprot|P29539 Saccharomyces cerevisiae YBR275C RIF1 Protein that binds to the Rap1p C-terminus and acts synergistically with Rif2p to help control telomere length and establish telomeric silencing deletion results in telomere elongation
similar to uniprot|P38147 Saccharomyces cerevisiae YBR274W CHK1 checkpoint kinase 1
similar to uniprot|P38349 Saccharomyces cerevisiae YBR273C UBX7 UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p
weakly similar to uniprot|P47048 Saccharomyces cerevisiae YJL049W Hypothetical ORF
similar to uniprot|P38348 Saccharomyces cerevisiae YBR272C
highly similar to uniprot|P47047 Saccharomyces cerevisiae YJL050W MTR4 Dead-box family ATP dependent helicase required for mRNA export from the nucleus co-factor of the exosome complex required for 3' end formation of 5.8S rRNA
weakly similar to uniprot|P47046 Saccharomyces cerevisiae YJL051W Protein of unknown function localized to the bud tip mRNA is targeted to the bud via the mRNA transport system involving She2p
highly similar to uniprot|P40335 Saccharomyces cerevisiae YJL053W PEP8 vacuolar protein sorting protein that forms part of the multimeric membrane-associated retromer complex
weakly similar to uniprot|P47045 Saccharomyces cerevisiae YJL054W TIM54 Translocase Inner Membrane 54kD Translocase for the insertion of proteins into the mitochondrial inner membrane
some similarities with uniprot|P47043 Saccharomyces cerevisiae YJL056C ZAP1 Zinc-regulated transcription factor binds to zinc-responsive promoter elements to induce transcription of certain genes in the presence of zinc regulates its own transcription contains seven zinc- finger domains
weakly similar to uniprot|Q02486 Saccharomyces cerevisiae YMR072W ABF2 Mitochondrial DNA-binding protein involved in mitochondrial DNA replication and recombination member of HMG1 DNA-binding protein family activity may be regulated by protein kinase A phosphorylation
some similarities with uniprot|P47042 Saccharomyces cerevisiae YJL057C probable serine/threonine kinase
some similarities with uniprot|P38346 Saccharomyces cerevisiae YBR270C BIT2 Hypothetical ORF
similar to uniprot|P47040 Saccharomyces cerevisiae YJL059W YHC3 Homolog of human CLN3 vacuolar/lysosomal membrane protein
weakly similar to uniprot|P42835 Saccharomyces cerevisiae YNL327W EGT2 Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase required for proper cell separation after cytokinesis expression is activated by Swi5p and tightly regulated in a cell cycle-dependent manner
highly similar to uniprot|P47039 Saccharomyces cerevisiae YJL060W BNA3 Arylformamidase
similar to uniprot|P38345 Saccharomyces cerevisiae YBR269C FMP21 The authentic non-tagged protein was localized to the mitochondria
weakly similar to uniprot|P40368 Saccharomyces cerevisiae YJL061W NUP82 Subunit of the nuclear pore complex (NPC) forms a subcomplex with Nup159p and Nsp1p interacts with Nup116p and is required for proper localization of Nup116p in the NPC
mitochondrial 54S ribosomal protein YmL37
similar to uniprot|P36532 Saccharomyces cerevisiae YBR268W MRPL37 Mitochondrial ribosomal protein of the large subunit
similar to uniprot|P40367 Saccharomyces cerevisiae YJL062W LAS21 Integral plasma membrane protein involved in the synthesis of the glycosylphosphatidylinositol (GPI) core structure mutations affect cell wall integrity
similar to uniprot|P38344 Saccharomyces cerevisiae YBR267W REI1 Protein of unknown function involved in bud growth in the mitotic signaling network proposed negative regulator of Swe1p and Gin4p contains dispersed C2H2 zinc finger domains
similar to uniprot|P38342 Saccharomyces cerevisiae YBR265W TSC10 catalyzes the second step in the synthesis of phytosphingosine 3-ketosphinganine reductase
highly similar to uniprot|Q3E7B2 Saccharomyces cerevisiae YJL062W-A Hypothetical ORF
mitochondrial 54S ribosomal protein YmL8
similar to uniprot|P22353 Saccharomyces cerevisiae YJL063C MRPL8 Mitochondrial ribosomal protein of the large subunit
similar to uniprot|P53206 Saccharomyces cerevisiae YGR012W Hypothetical ORF
similar to uniprot|P38148 Saccharomyces cerevisiae YBR276C PPS1 Protein phosphatase with specificity for serine threonine and tyrosine residues has a role in the DNA synthesis phase of the cell cycle
some similarities with uniprot|P27344 Saccharomyces cerevisiae YBR278W DPB3 Third-largest subunit of DNA polymerase II (DNA polymerase epsilon) required to maintain fidelity of chromosomal replication and also for inheritance of telomeric silencing mRNA abundance peaks at the G1/S boundary of the cell cycle
similar to uniprot|P40364 Saccharomyces cerevisiae YJL066C MPM1 Mitochondrial membrane protein of unknown function contains no hydrophobic stretches
similar to uniprot|P27614 Saccharomyces cerevisiae YJL172W CPS1 Vacuolar carboxypeptidase yscS expression is induced under low-nitrogen conditions
similar to uniprot|P38351 Saccharomyces cerevisiae YBR279W PAF1 RNA polymerase II-associated protein defines a large complex that is biochemically and functionally distinct from the Srb-Mediator form of Pol II holoenzyme and is required for full expression of a subset of cell cycle-regulated genes
highly similar to gnl|GLV|CAGL0J05324g Candida glabrata CAGL0J05324g and similar to YJL068C uniprot|P40363 Saccharomyces cerevisiae YJL068C Hypothetical ORF
similar to uniprot|P38352 Saccharomyces cerevisiae YBR280C Hypothetical ORF
similar to uniprot|P38149 Saccharomyces cerevisiae YBR281C Hypothetical ORF
similar to uniprot|P40362 Saccharomyces cerevisiae YJL069C UTP18 Possible U3 snoRNP protein involved in maturation of pre-18S rRNA based on computational analysis of large-scale protein-protein interaction data
mitochondrial 54S ribosomal protein YmL27
similar to uniprot|P36526 Saccharomyces cerevisiae YBR282W MRPL27 Mitochondrial ribosomal protein of the large subunit
highly similar to uniprot|P38353 Saccharomyces cerevisiae YBR283C SSH1 Subunit of the Ssh1 translocon complex Sec61p homolog involved in co-translational pathway of protein translocation not essential
similar to uniprot|P38340 Saccharomyces cerevisiae YBR261C Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family
similar to uniprot|P38339 Saccharomyces cerevisiae YBR260C RGD1 GTPase-activating protein (RhoGAP) for Rho3p and Rho4p possibly involved in control of actin cytoskeleton organization
some similarities with uniprot|P47050 Saccharomyces cerevisiae YJL047C RTT101 Cullin family member subunit of a complex containing ubiquitin ligase activity binds HRT1 and is modified by the ubiquitin like protein RUB1 Regulator of Ty1 Transposition Regulator of Ty1 Transposition
some similarities with uniprot|P38337 Saccharomyces cerevisiae YBR258C SHG1 Subunit of the COMPASS complex which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres
similar to uniprot|P38336 Saccharomyces cerevisiae YBR257W POP4 Subunit of both RNase MRP which cleaves pre-rRNA and nuclear RNase P which cleaves tRNA precursors to generate mature 5' ends binds to the RPR1 RNA subunit in Rnase P
similar to uniprot|P47051 Saccharomyces cerevisiae YJL046W Hypothetical ORF
similar to uniprot|P43606 Saccharomyces cerevisiae YFR029W PTR3 Component of the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p) which senses external amino acid concentration and transmits intracellular signals that result in regulation of expression of amino acid permease genes
similar to uniprot|P46669 Saccharomyces cerevisiae YOR340C RPA43 RNA polymerase I subunit A43
similar to uniprot|P39731 Saccharomyces cerevisiae YAL034W-A MTW1 Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to those contacting microtubules critical to kinetochore assembly
similar to uniprot|Q06855 Saccharomyces cerevisiae YOR338W Hypothetical ORF
similar to uniprot|P47988 Saccharomyces cerevisiae YOR337W TEA1 Mutants are defective in Ty1 Enhancer-mediated Activation Ty1 enhancer activator and to YLR098C uniprot|P43634 Saccharomyces cerevisiae YLR098C CHA4 Zinc-finger protein with Zn[2]-Cys[6] fungal-type binuclear cluster domain; DNA-binding transcriptional activator or CHA1
weakly similar to uniprot|P22023 Saccharomyces cerevisiae YOR336W KRE5 Protein required for beta-1 6 glucan biosynthesis mutations result in aberrant morphology and severe growth defects
highly similar to uniprot|P40825 Saccharomyces cerevisiae YOR335C ALA1 Cytoplasmic alanyl-tRNA synthetase required for protein synthesis point mutation (cdc64-1 allele) causes cell cycle arrest at G1 lethality of null mutation is functionally complemented by human homolog
similar to uniprot|P28005 Saccharomyces cerevisiae YAL033W POP5 Subunit of both RNase MRP which cleaves pre-rRNA and nuclear RNase P which cleaves tRNA precursors to generate mature 5' ends
similar to uniprot|P28004 Saccharomyces cerevisiae YAL032C PRP45 Ortholog of human transcriptional coactivator SKIP can activate transcription of a reporter gene interacts with splicing factors Prp22p and Prp46p
some similarities with uniprot|P39732 Saccharomyces cerevisiae YAL031C FUN21 Cytoplasmic protein of unknown function potential Cdc28p substrate
similar to uniprot|Q01926 Saccharomyces cerevisiae YOR334W MRS2 Mitochondrial inner membrane Mg(2) channel required for maintenance of intramitochondrial Mg(2) concentrations at the correct level to support splicing of group II introns
similar to uniprot|P22203 Saccharomyces cerevisiae YOR332W VMA4 vacuolar ATPase V1 domain subunit E (27 kDa)
DNA transposon of KLLA part of the newly discovered ROVER DNA transposon family of the Kluyveromyces: degenerate copy
some similarities with uniprot|P34758 Saccharomyces cerevisiae YOR329C SCD5 Multicopy suppressor of clathrin deficiency and of ts ipl1 mutants
weakly similar to uniprot|Q03362 Saccharomyces cerevisiae YDR476C Hypothetical ORF
some similarities with uniprot|Q99248 Saccharomyces cerevisiae YOR019W Hypothetical ORF
uniprot|Q96W95 Kluyveromyces lactis MSH2 Mismatch repair protein Msh2p
similar to uniprot|P38115 Saccharomyces cerevisiae YBR149W ARA1 Large subunit of NADP dependent arabinose dehydrogenase involved in carbohydrate metabolism small subunit is unidentified
some similarities with uniprot|Q12180 Saccharomyces cerevisiae YOL089C HAL9 Putative transcription factor containing a zinc finger overexpression increases salt tolerance through increased expression of the ENA1 (Na /Li extrusion pump) gene while gene disruption decreases both salt tolerance and ENA1 expression
similar to uniprot|P38281 Saccharomyces cerevisiae YBR151W APD1 Protein of unknown function required for normal localization of actin patches and for normal tolerance of sodium ions and hydrogen peroxide localizes to both cytoplasm and nucleus
similar to uniprot|Q99316 Saccharomyces cerevisiae YOL088C MPD2 Protein disulfide isomerase
some similarities with uniprot|P42946 Saccharomyces cerevisiae YJL108C PRM10 Pheromone-regulated protein predicted to have 5 transmembrane segments
similar to uniprot|P32581 Saccharomyces cerevisiae YJL106W IME2 Serine/threonine protein kinase involved in activation of meiosis associates with Ime1p and mediates its stability activates Ndt80p IME2 expression is positively regulated by Ime1p
similar to uniprot|P36124 Saccharomyces cerevisiae YKR029C SET3
similar to uniprot|Q03151 Saccharomyces cerevisiae YMR097C MTG1 Peripheral GTPase of the mitochondrial inner membrane
similar to uniprot|P34253 Saccharomyces cerevisiae YKL110C KTI12 Protein associated with the RNA polymerase II Elongator complex involved in sensitivity to G1 arrest induced by Kluyveromyces lactis toxin zymocin
weakly similar to uniprot|Q03153 Saccharomyces cerevisiae YMR098C Hypothetical ORF
uniprot|P26375 Kluyveromyces lactis KLLA0F02970g BAF1 Transcription factor BAF1
similar to uniprot|P26793 Saccharomyces cerevisiae YKL113C RAD27 5' to 3' exonuclease 5' flap endonuclease required for Okazaki fragment processing and maturation as well as for long-patch base-excision repair member of the S. pombe RAD2/FEN1 family
similar to uniprot|P32497 Saccharomyces cerevisiae YMR309C NIP1 Subunit of the eukaryotic translation initiation factor 3 (eIF3) involved in the assembly of preinitiation complex and start codon selection
highly similar to uniprot|P15703 Saccharomyces cerevisiae YGR282C BGL2 Endo-beta-1 3-glucanase major protein of the cell wall involved in cell wall maintenance
similar to uniprot|Q04867 Saccharomyces cerevisiae YMR310C Hypothetical ORF
similar to uniprot|P41818 Saccharomyces cerevisiae YMR311C GLC8 Regulatory subunit of protein phosphatase 1 (Glc7p) involved in glycogen metabolism and chromosome segregation proposed to regulate Glc7p activity via conformational alteration ortholog of the mammalian protein phosphatase inhibitor 2
similar to uniprot|P53337 Saccharomyces cerevisiae YGR284C ERV29 Protein localized to COPII-coated vesicles involved in vesicle formation and incorporation of specific secretory cargo
highly similar to uniprot|P32527 Saccharomyces cerevisiae YGR285C ZUO1 Cytosolic ribosome-associated chaperone contains a DnaJ domain together with Ssz1p acts as a chaperone for nascent polypeptide chains
similar to uniprot|Q08268 Saccharomyces cerevisiae YOL119C MCH4 or uniprot|Q08777 Saccharomyces cerevisiae YOR306C MCH5
similar to uniprot|P03965 Saccharomyces cerevisiae YJR109C CPA2 Large subunit of carbamoyl phosphate synthetase, which catalyzes a step in the synthesis of citrulline, an arginine precursor
similar to uniprot|P33303 Saccharomyces cerevisiae YJR095W SFC1 Mitochondrial succinate-fumarate transporter transports succinate into and fumarate out of the mitochondrion required for ethanol and acetate utilization
highly similar to uniprot|P47137 Saccharomyces cerevisiae YJR096W
similar to uniprot|P53943 Saccharomyces cerevisiae YNL065W AQR1 Plasma membrane transporter of the major facilitator superfamily that confers resistance to short-chain monocarboxylic acids and quinidine
highly similar to uniprot|P25491 Saccharomyces cerevisiae YNL064C YDJ1 yeast dnaJ homolog (nuclear envelope protein) heat shock protein
similar to uniprot|P53944 Saccharomyces cerevisiae YNL063W MTQ1
similar to uniprot|P41814 Saccharomyces cerevisiae YNL062C GCD10 Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p required for the modification of the adenine at position 58 in tRNAs especially tRNAi-Met first identified as a negative regulator of GCN4 expression
similar to uniprot|P40991 Saccharomyces cerevisiae YNL061W NOP2 Probable RNA m(5)C methyltransferase essential for processing and maturation of 27S pre-rRNA and large ribosomal subunit biogenesis localized to the nucleolus
similar to uniprot|P53946 Saccharomyces cerevisiae YNL059C ARP5 Nuclear actin-related protein involved in chromatin remodeling component of chromatin-remodeling enzyme complexes
highly similar to uniprot|Q00245 Saccharomyces cerevisiae YIL118W RHO3 Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins involved in the establishment of cell polarity GTPase activity positively regulated by the GTPase activating protein (GAP) Rgd1p
similar to uniprot|P53949 Saccharomyces cerevisiae YNL056W Cytoplasmic protein required for replication of Brome mosaic virus in S. cerevisiae which is a model system for studying replication of positive-strand RNA viruses in their natural hosts
similar to uniprot|P07172 Saccharomyces cerevisiae YIL116W HIS5 Histidinol-phosphate aminotransferase catalyzes the seventh step in histidine biosynthesis responsive to general control of amino acid biosynthesis mutations cause histidine auxotrophy and sensitivity to Cu Co and Ni salts
some similarities with uniprot|P40477 Saccharomyces cerevisiae YIL115C NUP159 Subunit of the nuclear pore complex that is found exclusively on the cytoplasmic side forms a subcomplex with Nup82p and Nsp1p
similar to uniprot|P04840 Saccharomyces cerevisiae YNL055C POR1 Mitochondrial porin (voltage-dependent anion channel) outer membrane protein required for the maintenance of mitochondrial osmotic stability and mitochondrial membrane permeability
weakly similar to uniprot|P53950 Saccharomyces cerevisiae YNL054W VAC7 Integral vacuolar membrane protein may function to regulate Fab1p kinase activity
similar to uniprot|P38590 Saccharomyces cerevisiae YNL053W MSG5 Dual-specificity protein phosphatase required for maintenance of a low level of signaling through the cell integrity pathway regulates and is regulated by Slt2p also required for adaptive response to pheromone
similar to uniprot|P40480 Saccharomyces cerevisiae YIL112W HOS4 Subunit of the Set3 complex which is a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity potential Cdc28p substrate
similar to uniprot|P00425 Saccharomyces cerevisiae YIL111w COX5B or uniprot|P00424 Saccharomyces cerevisiae YNL052w COX5A, subunit Va or Vb of cytochrome c oxidase
similar to uniprot|P40481 Saccharomyces cerevisiae YIL110W Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family
similar to uniprot|P53951 Saccharomyces cerevisiae YNL051W COG5 Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p) a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
weakly similar to uniprot|P53952 Saccharomyces cerevisiae YNL050C Hypothetical ORF
similar to uniprot|P40482 Saccharomyces cerevisiae YIL109C SEC24 The Sec23p-Sec24p complex is one of three cytoplamic COPII factors involved in ER to Golgi transport vesicle coat component
similar to uniprot|P40483 Saccharomyces cerevisiae YIL108W Hypothetical ORF
similar to uniprot|P40433 Saccharomyces cerevisiae YIL107C PFK26 6-phosphofructo-2-kinase inhibited by phosphoenolpyruvate and sn-glycerol 3-phosphate has negligible fructose-2 6-bisphosphatase activity transcriptional regulation involves protein kinase A
similar to uniprot|P40484 Saccharomyces cerevisiae YIL106W MOB1 Mps One Binder;(putative) transcriptional regulator involved in mitosis
similar to uniprot|P53954 Saccharomyces cerevisiae YNL048W ALG11 Alpha-1 2-mannosyltransferase catalyzes addition of the terminal alpha 1 2-Man to the Man5GlcNAc2-PP-dolichol intermediate during asparagine-linked glycosylation in the ER
similar to uniprot|P40485 Saccharomyces cerevisiae YIL105C SLM1 Phosphoinositide PI4 5P(2) binding protein forms a complex with Slm2p acts downstream of Mss4p in a pathway regulating actin cytoskeleton organization in response to stress phosphorylated by the Tor2p-containing complex TORC2
similar to uniprot|Q10740 Saccharomyces cerevisiae YNL045W Similar to human LTA4 hydrolase but in vivo substrates not yet defined.
similar to uniprot|P53633 Saccharomyces cerevisiae YNL044W YIP3 Interacts with YPT proteins
weakly similar to uniprot|P53958 Saccharomyces cerevisiae YNL042W BOP3 Protein of unknown function potential Cdc28p substrate overproduction suppresses a pam1 slv3 double null mutation
similar to uniprot|P40486 Saccharomyces cerevisiae YIL104C SHQ1 Essential nuclear protein required for accumulation of box H/ACA snoRNAs and for rRNA processing interacts with Naf1p
highly similar to uniprot|P40487 Saccharomyces cerevisiae YIL103W DPH1 Protein required along with Dph2p Kti11p Jjj3p and Dph5p for synthesis of diphthamide which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p) may act in a complex with Dph2p and Kti11p
similar to uniprot|P53959 Saccharomyces cerevisiae YNL041C COG6 Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p) a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
weakly similar to uniprot|P40489 Saccharomyces cerevisiae YIL101C XBP1 Transcriptional repressor that binds to promoter sequences of the cyclin genes CYS3 and SMF2 expression is induced by stress or starvation during mitosis and late in meiosis member of the Swi4p/Mbp1p family potential Cdc28p substrate
similar to uniprot|P53615 Saccharomyces cerevisiae YNL036W NCE103 Carbonic anhydrase poorly transcribed under aerobic conditions and at an undetectable level under anaerobic conditions involved in non-classical protein export pathway
similar to uniprot|P08019 Saccharomyces cerevisiae YIL099W SGA1 Intracellular sporulation-specific glucoamylase involved in glycogen degradation induced during starvation of a/a diploids late in sporulation but dispensable for sporulation
similar to uniprot|P40491 Saccharomyces cerevisiae YIL098C FMC1 Mitochondrial matrix protein required for assembly or stability at high temperature of the F1 sector of mitochondrial F1F0 ATP synthase
uniprot|O94229 Kluyveromyces lactis KLLA0F04103g IDH1 Isocitrate dehydrogenase subunit 1
similar to uniprot|P38361 uniprot|P38361 Saccharomyces cerevisiae YBR296C PHO89 Na+/Pi cotransporter active in early growth phase
similar to uniprot|P19735 Saccharomyces cerevisiae YBR055C PRP6 Splicing factor component of the U4/U6-U5 snRNP complex
similar to uniprot|P40971 Saccharomyces cerevisiae YDR034C LYS14 Transcriptional activator involved in regulation of genes of the lysine biosynthesis pathway requires 2-aminoadipate semialdehyde as co-inducer
some similarities with uniprot|Q05497 Saccharomyces cerevisiae YDR338C Hypothetical ORF
similar to uniprot|P38235 Saccharomyces cerevisiae YBR053C Hypothetical ORF
highly similar to uniprot|Q12335 Saccharomyces cerevisiae YDR032C PST2 Protein of unknown function with similarity to members of a family of flavodoxin-like proteins; induced by oxidative stress in a Yap1p dependent manner; GFP-fusion protein localizes to the cytoplasm in a punctate pattern
weakly similar to uniprot|Q00816 Saccharomyces cerevisiae YDR028C REG1 Regulatory subunit of type 1 protein phosphatase Glc7p involved in negative regulation of glucose-repressible genes involved in RNA processing
similar to uniprot|Q12071 Saccharomyces cerevisiae YDR027C VPS54 Component of the GARP (Golgi-associated retrograde protein) complex
uniprot|Q05950 Kluyveromyces lactis KLLA0F04389g REB1 DNA-binding protein REB1
some similarities with uniprot|P40472 Saccharomyces cerevisiae YIL123W SIM1 (putative) involved in control of DNA replication
similar to uniprot|P40471 Saccharomyces cerevisiae YIL124W AYR1 NADPH-dependent 1-acyl dihydroxyacetone phosphate reductase found in lipid particles and ER involved in phosphatidic acid biosynthesis and required for spore germination capable of metabolizing mammalian steroid hormones
highly similar to uniprot|P20967 Saccharomyces cerevisiae YIL125W KGD1 Component of the mitochondrial alpha-ketoglutarate dehydrogenase complex which catalyzes a key step in the tricarboxylic acid (TCA) cycle the oxidative decarboxylation of alpha-ketoglutarate to form succinyl-CoA
highly similar to uniprot|P05738 Saccharomyces cerevisiae uniprot|P05738 Saccharomyces cerevisiae YGL147C RPL9A Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl9Bp and has similarity to E. coli L6 and rat L9 ribosomal proteins and to YNL067W uniprot|P51401 Saccharomyces cerevisiae YNL067W RPL9B Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl9Ap and has similarity to E. coli L6 and rat L9 ribosomal proteins
similar to uniprot|P32597 Saccharomyces cerevisiae YIL126W STH1 helicase related protein snf2 homolog
similar to uniprot|P40470 Saccharomyces cerevisiae YIL127C Hypothetical ORF
similar to uniprot|P40469 Saccharomyces cerevisiae YIL128W MET18 DNA repair and TFIIH regulator required for both nucleotide excision repair (NER) and RNA polymerase II (RNAP II) transcription possible role in assembly of a multiprotein complex(es) required for NER and RNAP II transcription
similar to uniprot|P40468 Saccharomyces cerevisiae YIL129C TAO3 Identified in a hunt for mutants that activate OCH1 transcription Transcriptional Activator of OCH1
similar to uniprot|P40467 Saccharomyces cerevisiae YIL130W ASG1 Proposed transcriptional activator member of the Gal4p family of zinc cluster proteins
similar to uniprot|P40466 Saccharomyces cerevisiae YIL131C FKH1 Transcription factor of the forkhead family that regulates the cell cycle and pseudohyphal growth also involved in chromatin silencing at HML and HMR
weakly similar to uniprot|Q45U15 Saccharomyces cerevisiae YIL132C CSM2
highly similar to uniprot|P26784 Saccharomyces cerevisiae YIL133C RPL16A N-terminally acetylated protein component of the large (60S) ribosomal subunit, binds to 5. 8 S rRNA; has similarity to Rpl16Bp, E. coli L13 and rat L13a ribosomal proteins; transcriptionally regulated by Rap1p and to YNL069C uniprot|P26785 Saccharomyces cerevisiae YNL069C RPL16B N-terminally acetylated protein component of the large (60S) ribosomal subunit, binds to 5. 8 S rRNA; has similarity to Rpl16Ap, E. coli L13 and rat L13a ribosomal proteins; transcriptionally regulated by Rap1p
similar to uniprot|P40464 Saccharomyces cerevisiae YIL134W FLX1 Protein required for transport of flavin adenine dinucleotide (FAD) from mitochondria where it is synthesized from riboflavin to the cytosol
similar to uniprot|P12695 Saccharomyces cerevisiae YNL071W LAT1 Dihydrolipoamide acetyltransferase component (E2) of pyruvate dehydrogenase complex which catalyzes the oxidative decarboxylation of pyruvate to acetyl-CoA
similar to uniprot|P53942 Saccharomyces cerevisiae YNL072W RNH201 Ribonuclease H2 catalytic subunit removes RNA primers during Okazaki fragment synthesis cooperates with Rad27p nuclease
similar to uniprot|P32048 Saccharomyces cerevisiae YNL073W MSK1 Mitochondrial lysine-tRNA synthetase required for import of both aminoacylated and deacylated forms of tRNA(Lys) into mitochondria
similar to uniprot|P20457 Saccharomyces cerevisiae YKL045W PRI2 Subunit of DNA primase which is required for DNA synthesis and double-strand break repair
some similarities with uniprot|P53438 Saccharomyces cerevisiae YMR016C SOK2 Protein that can when overexpressed suppress mutants of cAMP-dependent protein kinase displays homologies to several transcription factors
weakly similar to uniprot|P36094 Saccharomyces cerevisiae YKL042W Spindle pole body component SPC42
highly similar to uniprot|P53622 Saccharomyces cerevisiae YDL145C COP1 Alpha subunit of COPI vesicle coatomer complex which surrounds transport vesicles in the early secretory pathway
similar to uniprot|Q05790 Saccharomyces cerevisiae YLR213C
similar to uniprot|Q07589 Saccharomyces cerevisiae YDL144C Hypothetical ORF
similar to uniprot|P32791 Saccharomyces cerevisiae YLR214W FRE1 Ferric reductase and cupric reductase reduces siderophore-bound iron and oxidized copper prior to uptake by transporters expression induced by low copper and iron levels
similar to uniprot|Q05791 Saccharomyces cerevisiae YLR215C CDC123
highly similar to uniprot|P39078 Saccharomyces cerevisiaeYDL143W CCT4 Subunit of the cytosolic chaperonin Cct ring complex related to Tcp1p
similar to uniprot|Q07560 Saccharomyces cerevisiae YDL142C CRD1 Cardiolipin synthase produces cardiolipin which is an important constituent of mitochondrial membranes required for normal mitochondrial membrane potential and function
similar to uniprot|P48445 Saccharomyces cerevisiae YDL141W BPL1 Biotin:apoprotein ligase
highly similar to uniprot|P04050 Saccharomyces cerevisiae YDL140C
similar to uniprot|P53691 Saccharomyces cerevisiae YLR216C CPR6 Peptidyl-prolyl cis-trans isomerase (cyclophilin) catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues binds to Hsp82p and contributes to chaperone activity
similar to uniprot|Q12334 Saccharomyces cerevisiae YDL139C SCM3 Suppressor of chromosome missegregation
similar to uniprot|Q05809 Saccharomyces cerevisiae YLR218C Hypothetical ORF
similar to uniprot|P38968 Saccharomyces cerevisiae YDL195W SEC31 involved in protein transport from endoplasmic reticulum to Golgi Component (p150) of COPII coat of secretory pathway vesicles
uniprot|O13477 Kluyveromyces lactis RAG4 Putative glucose sensor
similar to uniprot|Q12063 Saccharomyces cerevisiae YDL193W NUS1
highly similar to uniprot|P11076 Saccharomyces cerevisiae YDL192W ARF1 ADP-ribosylation factor GTPase of the Ras superfamily involved in regulation of coated formation vesicles in intracellular trafficking within the Golgi functionally interchangeable with Arf2p
highly similar to uniprot|P39741 Saccharomyces cerevisiae YDL191W RPL35A and YDL136W RPL35B, proteins component of the large (60S) ribosomal subunit
similar to uniprot|P54860 Saccharomyces cerevisiae YDL190C UFD2 Ubiquitin chain assembly factor (E4)
weakly similar to uniprot|Q870H2 Saccharomyces cerevisiae YDL189W RBS1 Protein of unknown function identified as a high copy suppressor of psk1 psk2 mutations that confer temperature-sensitivity for galactose utilization proposed to bind single-stranded nucleic acids via its R3H domain
highly similar to uniprot|Q12434 Saccharomyces cerevisiae YDL135C RDI1 Rho GDP dissociation inhibitor
highly similar to uniprot|P23594 Saccharomyces cerevisiae YDL134C PPH21 Catalytic subunit of protein phosphatase 2A functionally redundant with Pph22p methylated at C terminus forms alternate complexes with several regulatory subunits involved in signal transduction and regulation of mitosis
some similarities with uniprot|P48568 Saccharomyces cerevisiae YDL186W Hypothetical ORF
highly similar to uniprot|P17255 Saccharomyces cerevisiae YDL185W TFP1 Vacuolar ATPase V1 domain subunit A protein precursor is spliced to yield the extein Tfp1p and the intein Vde (PI-SceI) which is a site-specific endonuclease
similar to uniprot|P48569 Saccharomyces cerevisiae YDL183C Hypothetical ORF
weakly similar to uniprot|Q12516 Saccharomyces cerevisiae YDL133W
similar to uniprot|Q12018 Saccharomyces cerevisiae YDL132W CDC53 Cullin structural protein of SCF complexes (which also contain Skp1p Cdc34p and an F-box protein) involved in ubiquitination SCF promotes the G1-S transition by targeting G1 cyclins and the Cln-CDK inhibitor Sic1p for degradation
highly similar to uniprot|Q12122 Saccharomyces cerevisiae YDL131W LYS21 and to uniprot|P48570 Saccharomyces cerevisiae YDL182W LYS20 homocitrate synthase
weakly similar to uniprot|P01097 Saccharomyces cerevisiae YDL181W INH1 Protein that inhibits ATP hydrolysis by the F1F0-ATP synthase inhibitory function is enhanced by stabilizing proteins Stf1p and Stf2p has similarity to Stf1p and both Inh1p and Stf1p exhibit the potential to form coiled-coil structures
highly similar to uniprot|P10622 Saccharomyces cerevisiae YDL130W RPP1B Ribosomal protein P1 beta a component of the ribosomal stalk which is involved in the interaction between translational elongation factors and the ribosome accumulation of P1 in the cytoplasm is regulated by phosphorylation and interaction with the P2 stalk component
weakly similar to uniprot|Q07555 Saccharomyces cerevisiae YDL129W Hypothetical ORF
similar to uniprot|Q12301 Saccharomyces cerevisiae YDL180W Hypothetical ORF
similar to uniprot|O13581 Saccharomyces cerevisiae YDL128W
weakly similar to uniprot|P25693 Saccharomyces cerevisiae YDL127W PCL2 G1 cyclin associates with Pho85p cyclin-dependent kinase (Cdk) to contribute to entry into the mitotic cell cycle essential for cell morphogenesis localizes to sites of polarized cell growth
highly similar to uniprot|P25694 Saccharomyces cerevisiae YDL126C CDC48 ATPase in ER nuclear membrane and cytosol with homology to mammalian p97 in a complex with Npl4p and Ufd1p participates in retrotranslocation of ubiquitinated proteins from the ER into the cytosol for degradation by the proteasome
highly similar to uniprot|Q04344 Saccharomyces cerevisiae YDL125C
highly similar to uniprot|P46681 Saccharomyces cerevisiae YDL178W DLD2 D-lactate dehydrogenase located in the mitochondrial matrix
highly similar to uniprot|Q07551 Saccharomyces cerevisiae YDL124W NADPH-dependent alpha-keto amide reductase reduces aromatic alpha-keto amides aliphatic alpha-keto esters and aromatic alpha-keto esters
similar to uniprot|Q12257 Saccharomyces cerevisiae YDL177C Hypothetical ORF
similar to uniprot|Q12027 Saccharomyces cerevisiae YDL176W Hypothetical ORF
similar to uniprot|Q07549 Saccharomyces cerevisiae YDL123W SNA4 Protein of unknown function localized to the vacuolar outer membrane
similar to uniprot|P40507 Saccharomyces cerevisiae and similar to uniprot|Q12476 Saccharomyces cerevisiae YDL175C AIR2 RING finger proteins
highly similar to uniprot|P04801 Saccharomyces cerevisiae YIL078W THS1 Threonyl-tRNA synthetase cytoplasmic
weakly similar to uniprot|P40508 Saccharomyces cerevisiae YIL077C Hypothetical ORF
highly similar to uniprot|P25627 Saccharomyces cerevisiae YCR047C BUD23 Protein involved in bud-site selection diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
mitochondrial 54S ribosomal protein IMG1
similar to uniprot|P25626 Saccharomyces cerevisiae YCR046C IMG1 Mitochondrial ribosomal protein of the small subunit required for respiration and for maintenance of the mitochondrial genome
similar to uniprot|P53721 Saccharomyces cerevisiae YNR018W Hypothetical ORF
some similarities with uniprot|P25036 Saccharomyces cerevisiae YOR003W YSP3 subtilisin-like protease III
similar to uniprot|P32897 Saccharomyces cerevisiae YNR017W MAS6 Essential protein of the mitochondrial inner membrane component of the mitochondrial import system
highly similar to uniprot|Q00955 Saccharomyces cerevisiae YNR016C ACC1 Acetyl-CoA carboxylase biotin containing enzyme that catalyzes the carboxylation of acetyl-CoA to form malonyl-CoA required for de novo biosynthesis of long-chain fatty acids
similar to uniprot|P53720 Saccharomyces cerevisiae YNR015W SMM1 tRNA dihydrouridine synthase
some similarities with uniprot|Q03695 Saccharomyces cerevisiae YMR206W Hypothetical ORF
similar to uniprot|P27514 Saccharomyces cerevisiae YNR013C PHO91 Low-affinity phosphate transporter deletion of pho84 pho87 pho89 pho90 and pho91 causes synthetic lethality transcription independent of Pi and Pho4p activity overexpression results in vigorous growth
similar to uniprot|P27515 Saccharomyces cerevisiae YNR012W URK1 converts ATP and uridine to ADP and UMP Uridine kinase
similar to uniprot|P20095 Saccharomyces cerevisiae YNR011C PRP2 RNA-dependent ATPase in the DEAH-box family required for activation of the spliceosome before the first transesterification step in RNA splicing
similar to uniprot|P50107 Saccharomyces cerevisiae YML004C GLO1 Monomeric glyoxalase I catalyzes the detoxification of methylglyoxal (a by-product of glycolysis) via condensation with glutathione to produce S-D-lactoylglutathione expression regulated by methylglyoxal levels and osmotic stress
uniprot|Q03216 Kluyveromyces lactis KLLA0F06248g PFK2 6- phosphofructokinase subunit beta
some similarities with uniprot|Q03694 Saccharomyces cerevisiae YMR204C Hypothetical ORF
highly similar to uniprot|P23644 Saccharomyces cerevisiae YMR203W TOM40 Essential component of the preprotein translocase of the mitochondrial outer membrane (TOM complex) in which it constitutes the core element of the protein conducting pore
similar to uniprot|P33308 Saccharomyces cerevisiae YNR010W CSE2 Component of the Med9/10 module which is a subcomplex within the RNA polymerase II Mediator complex required for regulation of RNA polymerase II activity
highly similar to uniprot|P32352 Saccharomyces cerevisiae YMR202W ERG2 C-8 sterol isomerase catalyzes the isomerization of the delta-8 double bond to the delta-7 position at an intermediate step in ergosterol biosynthesis
similar to uniprot|P40345 Saccharomyces cerevisiae YNR008W LRO1 Acyltransferase that catalyzes diacylglycerol esterification one of several acyltransferases that contribute to triglyceride synthesis putative homolog of human lecithin cholesterol acyltransferase
similar to uniprot|P40344 Saccharomyces cerevisiae YNR007C ATG3 Protein involved in autophagy E2-like enzyme that plays a role in formation of Atg8p-phosphatidylethanolamine conjugates which are involved in membrane dynamics during autophagy
similar to uniprot|P28519 Saccharomyces cerevisiae YMR201C RAD14 Protein that recognizes and binds damaged DNA during nucleotide excision repair subunit of Nucleotide Excision Repair Factor 1 (NEF1) contains zinc finger motif homolog of human XPA protein
similar to uniprot|P40343 Saccharomyces cerevisiae YNR006W VPS27 hydrophilic protein has cysteine rich putative zinc finger esential for function
similar to uniprot|Q03691 Saccharomyces cerevisiae YMR200W ROT1 Protein that may be involved in cell wall function mutations in rot1 cause cell wall defects suppress tor2 mutations and are synthetically lethal with rot2 mutations
similar to uniprot|P20437 Saccharomyces cerevisiae YMR199W CLN1 role in cell cycle START G(sub)1 cyclin
weakly similar to uniprot|Q12365 Saccharomyces cerevisiae YPL255W BBP1 Protein required for the spindle pole body (SPB) duplication localized at the central plaque periphery forms a complex with a nuclear envelope protein Mps2p and SPB components Spc29p and Kar1p required for mitotic functions of Cdc5p
highly similar to uniprot|P32449 Saccharomyces cerevisiae YBR249C ARO4 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase
highly similar to uniprot|P33734 Saccharomyces cerevisiae YBR248C HIS7 Imidazole glycerol phosphate synthase (glutamine amidotransferase:cyclase) catalyzes the fifth and sixth steps of histidine biosynthesis and also produces 5-aminoimidazole-4-carboxamide ribotide (AICAR) a purine precursor
similar to uniprot|P21827 Saccharomyces cerevisiae YGL097W SRM1 Nucleotide exchange factor for Gsp1p localizes to the nucleus required for nucleocytoplasmic trafficking of macromolecules potentially phosphorylated by Cdc28p
similar to uniprot|P38333 Saccharomyces cerevisiae YBR247C ENP1 Protein associated with U3 and U14 snoRNAs required for pre-rRNA processing and 40S ribosomal subunit synthesis localized in the nucleus and concentrated in the nucleolus
similar to uniprot|P53146 Saccharomyces cerevisiae YGL098W USE1 Use1p is a SNARE and forms a complex with the SNAREs Sec22p Sec20p and Ufe1p. The protein is localized to the ER and use1 mutants show defects in retrograde traffic from the Golgi to the ER Protein required for cell viability
highly similar to uniprot|P53145 Saccharomyces cerevisiae YGL099W LSG1 Putative GTPase involved in 60S ribosomal subunit biogenesis localized to the cytoplasm
similar to uniprot|P38332 Saccharomyces cerevisiae YBR246W Hypothetical ORF
similar to uniprot|P38144 Saccharomyces cerevisiae YBR245C ISW1 Member of the imitation-switch (ISWI) class of ATP-dependent chromatin remodeling complexes ATPase that forms a complex with Ioc2p and Ioc4p to regulate transcription elongation and a complex with Ioc3p to repress transcription initiation
highly similar to uniprot|P40581 Saccharomyces cerevisiae YIR037W HYR1 Thiol peroxidase that functions as a hydroperoxide receptor to sense intracellular hydroperoxide levels and transduce a redox signal to the Yap1p transcription factor
similar to uniprot|P53011 Saccharomyces cerevisiae YGL100W SEH1 Nuclear pore protein homologous to Sec13p
similar to uniprot|P07286 Saccharomyces cerevisiae YBR243C ALG7 UDP-N-acetyl-glucosamine-1-P transferase transfers Glc-Nac-P from UDP-GlcNac to Dol-P in the ER in the first step of the dolichol pathway of protein asparagine-linked glycosylation inhibited by tunicamycin
similar to uniprot|P38331 Saccharomyces cerevisiae YBR242W Hypothetical ORF or YGL101W uniprot|P53144 Saccharomyces cerevisiae YGL101W Hypothetical ORF
uniprot|Q8J287 Kluyveromyces lactis RPL28 protein
similar to uniprot|P38142 Saccharomyces cerevisiae YBR241C Hypothetical ORF
similar to uniprot|P53735 Saccharomyces cerevisiae YNR039C ZRG17 Endoplasmic reticulum protein of unknown function transcription is induced under conditions of zinc deficiency mutant phenotype suggests a role in uptake of zinc
similar to uniprot|P25648 Saccharomyces cerevisiae YCR081W SRB8 RNA polymerase II mediator complex subunit
similar to uniprot|P53734 Saccharomyces cerevisiae YNR038W DBP6 Essential protein involved in ribosome biogenesis, putative ATP-dependent RNA helicase of the DEAD-box protein family
mitochondrial 37S ribosomal protein RSM19
highly similar to uniprot|P53733 Saccharomyces cerevisiae YNR037C
similar to uniprot|P25646 Saccharomyces cerevisiae YCR079W Hypothetical ORF
putative mitochondrial 37S ribosomal protein MRPS12
highly similar to uniprot|P53732 Saccharomyces cerevisiae YNR036C
similar to uniprot|P53731 Saccharomyces cerevisiae YNR035C ARC35 Subunit of the ARP2/3 complex which is required for the motility and integrity of cortical actin patches required for cortical localization of calmodulin
some similarities with uniprot|Q7LH06 Saccharomyces cerevisiae YDL048C STP4 Protein involved in pre-tRNA splicing and in uptake of branched-chain amino acids
highly similar to uniprot|Q765N3 Saccharomyces kluyveri Sk Delta 12-fatty acid desaturase
weakly similar to uniprot|P38985 Saccharomyces cerevisiae YDL092W SRP14 Signal recognition particle subunit
similar to uniprot|Q12229 YDL091c Saccharomyces cerevisiae UBX3 UBX domain-containing protein that interacts with Cdc48p
similar to uniprot|P22007 Saccharomyces cerevisiae YDL090C RAM1 essential for processing of ras proteins beta subunit of farnesyltransferase
weakly similar to uniprot|Q03792 Saccharomyces cerevisiae YMR154C
weakly similar to uniprot|Q12066 Saccharomyces cerevisiae YDL089W Protein of unknown function interacts with meiotic division protein Csm1p green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery potential Cdc28p substrate
some similarities with uniprot|Q05166 Saccharomyces cerevisiae YDL088C ASM4 Nuclear pore complex subunit part of a subcomplex also containing Nup53p Nup170p and Pse1p
similar to uniprot|Q07508 Saccharomyces cerevisiae YDL087C LUC7 Essential protein associated with the U1 snRNP complex splicing factor involved in recognition of 5' splice site
similar to uniprot|P28627 Saccharomyces cerevisiae YMR150c IMP1 protease, mitochondrial
similar to uniprot|Q02795 Saccharomyces cerevisiae YMR149W SWP1 oligosaccharyl transferase glycoprotein complex delta subunit
some similarities with uniprot|Q03083 Saccharomyces cerevisiae YPL034W Hypothetical ORF
similar to uniprot|Q07505 Saccharomyces cerevisiae YDL086W Hypothetical ORF
similar to uniprot|P40217 Saccharomyces cerevisiae YMR146C TIF34 Subunit of the core complex of translation initiation factor 3(eIF3) which is essential for translation
similar to uniprot|Q3E7B7 Saccharomyces cerevisiae YDL085C-A
similar to uniprot|P38995 Saccharomyces cerevisiae YDR270W CCC2 copper-transporting P-type ATPase with similarity to human Menkes and Wilsons genes; Cu(2+)-transporting ATPase
similar to uniprot|Q02792 Saccharomyces cerevisiae YOR048C RAT1 Nuclear 5' to 3' single-stranded RNA exonuclease involved in RNA metabolism including rRNA and snRNA processing as well as mRNA transcription termination
similar to uniprot|P31380 Saccharomyces cerevisiae YAL019W FUN30 Protein whose overexpression affects chromosome stability potential Cdc28p substrate homolog of Snf2p
similar to uniprot|Q08220 Saccharomyces cerevisiae YOL049W GSH2 Glutathione synthetase catalyzes the ATP-dependent synthesis of glutathione (GSH) from gamma-glutamylcysteine and glycine induced by oxidative stress and heat shock
uniprot|P32257 Kluyveromyces lactis KLLA0F07579g GAL11 Transcription regulatory protein GAL11
similar to uniprot|P31379 Saccharomyces cerevisiae YAL018C Hypothetical ORF
similar to uniprot|P31374 Saccharomyces cerevisiae YAL017W PSK1 One of two (see also PSK2) PAS domain containing S/T protein kinases coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status
similar to uniprot|P50276 Saccharomyces cerevisiae YGR055W MUP1 High affinity methionine permease
some similarities with uniprot|Q08215 Saccharomyces cerevisiae YOL044W PEX15 Phosphorylated tail-anchored type II integral peroxisomal membrane protein
highly similar to uniprot|P31383 Saccharomyces cerevisiae YAL016W TPD3 protein phosphatase 2A regulatory subunit A
similar to uniprot|Q08214 Saccharomyces cerevisiae YOL043C NTG2 DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase
similar to uniprot|Q08213 Saccharomyces cerevisiae YOL042W
similar to uniprot|P31377 Saccharomyces cerevisiae YAL014C SYN8 Endosomal SNARE related to mammalian syntaxin 8
similar to uniprot|Q08208 Saccharomyces cerevisiae YOL041C
similar to uniprot|Q758U6 Ashbya gossypii AEL344W and some similarities with YAL013W uniprot|P31385 Saccharomyces cerevisiae YAL013W DEP1 Transcriptional modulator involved in the regulation of structural genes involved in phospholipid biosynthesis also participates in regulation of metabolically unrelated genes as well as maintenance of mating efficiency and sporulation
highly similar to uniprot|Q01855 Saccharomyces cerevisiae YOL040C
highly similar to uniprot|P05319 Saccharomyces cerevisiae YOL039W RPP2A Ribosomal protein P2 alpha a component of the ribosomal stalk which is involved in the interaction between translational elongation factors and the ribosome regulates the accumulation of P1 (Rpp1Ap and Rpp1Bp) in the cytoplasm
highly similar to uniprot|P31373 Saccharomyces cerevisiae YAL012W CYS3 Cystathionine gamma-lyase catalyzes one of the two reactions involved in the transsulfuration pathway that yields cysteine from homocysteine with the intermediary formation of cystathionine
similar to uniprot|Q6B1H9 Saccharomyces cerevisiae YOL031C SIL1 ER-localized protein required for protein translocation into the ER interacts with the ATPase domain of the Kar2p chaperone suggesting some role in modulating its activity homolog of Yarrowia lipolytica SLS1 GrpE-like protein in the ER
similar to uniprot|Q08202 Saccharomyces cerevisiae YOL032W Hypothetical ORF
similar to uniprot|P48525 Saccharomyces cerevisiae YOL033W MSE1 Mitochondrial glutamyl-tRNA synthetase encoded by a nuclear gene
similar to uniprot|Q08204 YOL034W Saccharomyces cerevisiae YOL034W SMC5 Structural maintenance of chromosomes (SMC) protein, interacts with Rhc18p and Nse1p to form a large complex
some similarities with uniprot|P31376 Saccharomyces cerevisiae YAL011W SWC3 Protein of unknown function component of the Swr1p complex that incorporates Htz1p into chromatin
similar to uniprot|P18409 Saccharomyces cerevisiae YAL010C MDM10 Subunit of the mitochondrial sorting and assembly machinery (SAM complex) has a role in assembly of the TOM complex which mediates protein import through the outer membrane required for normal mitochondrial morphology and inheritance
similar to uniprot|P18410 Saccharomyces cerevisiae YAL009W SPO7 Integral nuclear/ER membrane protein of unknown function required for normal nuclear envelope morphology and sporulation
similar to uniprot|P38903 Saccharomyces cerevisiae YOR014W RTS1 B-type regulatory subunit of protein phosphatase 2A (PP2A)
some similarities with uniprot|P18411 Saccharomyces cerevisiae YAL008W FUN14 Mitochondrial protein of unknown function
highly similar to uniprot|Q06102 Saccharomyces cerevisiae YPR107C YTH1 Essential RNA-binding component of cleavage and polyadenylation factor
highly similar to uniprot|P53252 Saccharomyces cerevisiae YGR086C PIL1 Long chain base-responsive inhibitor of protein kinases Phk1p and Phk2p acts along with Lsp1p to down-regulate heat stress resistance via regulation of the Pkc1p and Ypk1p pathways phosphorylated by Phk1p and Phk2p
similar to uniprot|Q06096 Saccharomyces cerevisiae YPR105C COG4 component of oligomeric Golgi complex
similar to uniprot|P39521 Saccharomyces cerevisiae YPR104C
highly similar to uniprot|P30656 Saccharomyces cerevisiae YPR103W PRE2 20S proteasome beta-type subunit
highly similar to uniprot|P06380 Saccharomyces cerevisiae RPL11A and to uniprot|P06380 Saccharomyces cerevisiae YGR085C RPL11B component of the large (60S) ribosomal subunit
similar to uniprot|P12686 Saccharomyces cerevisiae YGR084C MRP13 Mitochondrial ribosomal protein of the small subunit
similar to uniprot|P12754 Saccharomyces cerevisiae YGR083C GCD2 Delta subunit of the translation initiation factor eIF2B the guanine-nucleotide exchange factor for eIF2 activity subsequently regulated by phosphorylated eIF2 first identified as a negative regulator of GCN4 expression
mitochondrial 54S ribosomal protein MRPL51
highly similar to uniprot|Q06090 Saccharomyces cerevisiae YPR100W MRPL51 Mitochondrial ribosomal protein of the large subunit
uniprot|P09608 Kluyveromyces lactis KLLA0F08393g GAL1 Galactokinase
uniprot|P09609 Kluyveromyces lactis KLLA0F08415g GAL10 GAL10 bifunctional protein
uniprot|P09580 Kluyveromyces lactis KLLA0F08437g GAL7 Galactose-1-phosphate uridylyltransferase
similar to uniprot|P12945 Saccharomyces cerevisiae YDL040C NAT1 Subunit of the N-terminal acetyltransferase NatA (Nat1p Ard1p Nat5p) N-terminally acetylates many proteins which influences multiple processes such as the cell cycle heat-shock resistance mating sporulation and telomeric silencing
similar to uniprot|Q02554 Saccharomyces cerevisiae YMR240C CUS1 Protein required for assembly of U2 snRNP into the spliceosome forms a complex with Hsh49p and Hsh155p
similar to uniprot|Q08774 Saccharomyces cerevisiae YOR305W Hypothetical ORF
similar to uniprot|Q08777 Saccharomyces cerevisiae YOR306C MCH5 Protein with similarity to mammalian monocarboxylate permeases which are involved in transport of monocarboxylic acids across the plasma membrane mutant is not deficient in monocarboxylate transport
highly similar to uniprot|Q04013 Saccharomyces cerevisiae YMR241W YHM2 Yeast suppressor gene of HM mutant (abf2) DNA-binding protein mtDNA stabilizing protein mitochondrial inner membrane protein with low homology to RIM2
similar to uniprot|P22215 Saccharomyces cerevisiae YOR307C SLY41 multicopy suppressor of ypt1 deletion homolog of chloroplast phosphate transporter
weakly similar to uniprot|Q12420 Saccharomyces cerevisiae YOR308C SNU66 66kD U4/U6.U5 snRNP associated protein
similar to uniprot|Q12499 Saccharomyces cerevisiae YOR310C NOP58 Protein involved in pre-rRNA processing 18S rRNA synthesis and snoRNA synthesis component of the small subunit processome complex which is required for processing of pre-18S rRNA
similar to uniprot|Q12382 Saccharomyces cerevisiae YOR311C HSD1 Endoplasmic reticulum (ER)-resident membrane protein overproduction induces enlargement of ER-like membrane structures and suppresses a temperature-sensitive sly1 mutation
highly similar to uniprot|P47913 Saccharomyces cerevisiae YOR312C RPL20B and highly similar to uniprot|P47913 Saccharomyces cerevisiae YMR242C RPL20A Protein component of the large (60S) ribosomal subunit
weakly similar to uniprot|P09937 Saccharomyces cerevisiae YOR313C SPS4 Protein whose expression is induced during sporulation not required for sporulation heterologous expression in E. coli induces the SOS response that senses DNA damage
weakly similar to uniprot|Q12507 Saccharomyces cerevisiae YOR315W Protein of unknown function found in the cytoplasm and the nucleus potential Cdc28p substrate
similar to uniprot|P20107 Saccharomyces cerevisiae YMR243C ZRC1 and to uniprot|P32798 Saccharomyces cerevisiae YOR316C COT1
similar to uniprot|Q04018 Saccharomyces cerevisiae YMR244W Hypothetical ORF
similar to uniprot|Q3E846 Saccharomyces cerevisiae YMR244C-A Hypothetical ORF
some similarities with uniprot|P43570 Saccharomyces cerevisiae YFL027C GYP8 GTPase-activating protein for yeast Rab family members Ypt1p is the preferred in vitro substrate but also acts on Sec4p Ypt31p and Ypt32p involved in the regulation of ER to Golgi vesicle transport
similar to uniprot|P38915 Saccharomyces cerevisiae YLR055C SPT8 Subunit of the SAGA transcriptional regulatory complex but not present in SAGA-like complex SLIK/SALSA required for SAGA-mediated inhibition at some promoters
similar to uniprot|P43569 Saccharomyces cerevisiae YFL028C CAF16 Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex involved in controlling mRNA initiation elongation and degradation putative ABC ATPase interacts with Ssn2p Ssn3p and Ssn8p
similar to uniprot|P32353 Saccharomyces cerevisiae YLR056W ERG3 C-5 sterol desaturase catalyzes the introduction of a C-5(6) double bond into episterol a precursor in ergosterol biosynthesis mutants are viable but cannot grow on non-fermentable carbon sources
uniprot|Q8J0L1 Kluyveromyces lactis cak1 Cyclin-dependent kinase activating kinase 1
weakly similar to uniprot|Q7LGY1 Saccharomyces cerevisiae YLR057W Hypothetical ORF
highly similar to uniprot|P37291 Saccharomyces cerevisiae YLR058C SHM2 serine hydroxymethyltransferase
similar to uniprot|P43567 Saccharomyces cerevisiae YFL030W
some similarities with uniprot|P41546 Saccharomyces cerevisiae YFL031W HAC1 bZIP transcription factor (ATF/CREB1 homolog) that regulates the unfolded protein response
similar to uniprot|P54964 Saccharomyces cerevisiae YLR059C REX2 RNA exonuclease required for U4 snRNA maturation functions redundantly with Rnh70p in 5.8S rRNA maturation and with Rnh70p and Rex3p in processing of U5 snRNA and RNase P RNA member of RNase D family of exonucleases
similar to uniprot|Q00362 Saccharomyces cerevisiae YGL190C CDC55 Non-essential regulatory subunit B of protein phosphatase 2A has multiple roles in mitosis and protein biosynthesis found in the nucleus of most cells but also at the bud neck (large-budded cells) and at the bud tip (small-budded cells)
highly similar to uniprot|P32799 Saccharomyces cerevisiae YGL191W COX13 Subunit VIa of cytochrome c oxidase which is the terminal member of the mitochondrial inner membrane electron transport chain not essential for cytochrome c oxidase activity but may modulate activity in response to ATP
similar to uniprot|P41833 Saccharomyces cerevisiae YGL192W IME4 Probable mRNA N6-adenosine methyltransferase that is required for IME1 transcript accumulation and for sporulation expression is induced in starved MATa/MAT alpha diploid cells
highly similar to uniprot|P53096 Saccharomyces cerevisiae YGL194C HOS2 Histone deacetylase required for gene activation via specific deacetylation of lysines in H3 and H4 histone tails subunit of the Set3 complex a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity
uniprot|Q8J0C9 Kluyveromyces lactis KLLA0F09141g gdp1 NADP glyceraldehyde 3-phosphate dehydrogenase
similar to uniprot|P53100 Saccharomyces cerevisiae YGL185C Putative hydroxyacid dehydrogenase
highly similar to uniprot|P39958 Saccharomyces cerevisiae YER136W GDI1 GDP dissociation inhibitor regulates vesicle traffic in secretory pathways by regulating the dissociation of GDP from the Sec4/Ypt/rab family of GTP binding proteins
highly similar to uniprot|P38203 Saccharomyces cerevisiae YBL026W LSM2 Component of small nuclear ribonucleoprotein complexes involved in RNA processing splicing and decay
similar to uniprot|P40083 Saccharomyces cerevisiae YER137C Hypothetical ORF
highly similar to uniprot|P05373 Saccharomyces cerevisiae YGL040C HEM2 Delta-aminolevulinate dehydratase a homo-octameric enzyme catalyzes the conversion of delta-aminolevulinic acid to porphobilinogen the second step in the heme biosynthetic pathway localizes to both the cytoplasm and nucleus
similar to uniprot|Q04272 Saccharomyces cerevisiae YMR077C VPS20 vaculolar protein sorting (putative)
similar to uniprot|P32582 Saccharomyces cerevisiae YGR155W CYS4 Cystathionine beta-synthase catalyzes the synthesis of cystathionine from serine and homocysteine the first committed step in cysteine biosynthesis
similar to uniprot|P0C5N3 Saccharomyces cerevisiae YGL041W-A Identified by expression profiling and mass spectrometry
similar to uniprot|P07273 YGL043W Saccharomyces cerevisiae DST1 General transcription elongation factor TFIIS
similar to uniprot|P25299 Saccharomyces cerevisiae YGL044C RNA15 Cleavage and polyadenylation factor I (CF I) component involved in cleavage and polyadenylation of mRNA 3' ends interacts with the A-rich polyadenylation signal in complex with Rna14p and Hrp1p
similar to uniprot|P40445 Saccharomyces cerevisiae YIL166C Hypothetical ORF, member of the Dal5p subfamily of the major facilitator family
weakly similar to uniprot|P25568 Saccharomyces cerevisiae YCL038C
highly similar to uniprot|P19882 Saccharomyces cerevisiae YLR259C HSP60 Tetradecameric mitochondrial chaperonin required for ATP-dependent folding of precursor polypeptides and complex assembly; prevents aggregation and mediates protein refolding after heat shock; role in mtDNA transmission; similarity to groEL
similar to uniprot|Q75EB2 Ashbya gossypii AAR165W AAR165Wp and weakly similar to YGL126W uniprot|P53012 Saccharomyces cerevisiae SCS3 Protein required for inositol prototrophy
some similarities with uniprot|P35995 Saccharomyces cerevisiae YKL222c
similar to uniprot|P38318 Saccharomyces cerevisiae YBR220C Hypothetical ORF
highly similar to uniprot|P32473 Saccharomyces cerevisiae YBR221C PDB1 E1 beta subunit of the pyruvate dehydrogenase (PDH) complex which is an evolutionarily-conserved multi-protein complex found in mitochondria
weakly similar to uniprot|P38319 Saccharomyces cerevisiae YBR223C TDP1 Tyrosine-DNA Phosphodiesterase
similar to uniprot|P53128 Saccharomyces cerevisiae YGL125W MET13 Isozyme of methylenetetrahydrofolate reductase catalyzes the reduction of 5 10-methylenetetrahydrofolate to 5-methyltetrahydrofolate in the methionine biosynthesis pathway
similar to uniprot|P38321 Saccharomyces cerevisiae YBR225W Hypothetical ORF
similar to uniprot|P38323 Saccharomyces cerevisiae YBR227C MCX1
similar to uniprot|P38324 Saccharomyces cerevisiae YBR228W SLX1 Subunit of a complex with Slx4p that hydrolyzes 5' branches from duplex DNA in response to stalled or converging replication forks function overlaps with that of Sgs1p-Top3p
similar to uniprot|P38138 Saccharomyces cerevisiae YBR229C ROT2 Glucosidase II catalytic subunit required for normal cell wall synthesis mutations in rot2 suppress tor2 mutations and are synthetically lethal with rot1 mutations
some similarities with uniprot|P40209 Saccharomyces cerevisiae YMR136W GAT2 Protein containing GATA family zinc finger motifs; similar to Gln3p and Dal80p
weakly similar to uniprot|P53129 Saccharomyces cerevisiae YGL124C MON1 Protein required for fusion of cvt-vesicles and autophagosomes with the vacuole associates as a complex with Ccz1p with a perivacuolar compartment potential Cdc28p substrate
similar to uniprot|P25443 Saccharomyces cerevisiae YGL123W RPS2
similar to uniprot|Q75E99 Ashbya gossypii AAR178C AAR178Cp and some similarites with YGL122C uniprot|P32505 Saccharomyces cerevisiae YGL122C NAB2 Nuclear polyadenylated RNA-binding protein related to human hnRNPs has a nuclear localization signal sequence that binds to Kap104p required for both poly(A) tail length control and nuclear export of mRNA
uniprot|Q00976 Kluyveromyces lactis KLLA0F09889g SPT16 FACT complex subunit SPT16
highly similar to uniprot|P22137 Saccharomyces cerevisiae YGL206C CHC1 vesicle coat protein presumed vesicle coat protein
similar to uniprot|P13711 Saccharomyces cerevisiae YGL205W POX1 Fatty-acyl coenzyme A oxidase involved in the fatty acid beta-oxidation pathway localized to the peroxisomal matrix
similar to uniprot|P08456 Saccharomyces cerevisiae YER026C CHO1 phosphatidylserine synthase
similar to uniprot|P09620 Saccharomyces cerevisiae YGL203C KEX1 Protease involved in the processing of killer toxin and alpha factor precursor cleaves Lys and Arg residues from the C-terminus of peptides and proteins
similar to uniprot|P53090 Saccharomyces cerevisiae YGL202W ARO8 Aromatic aminotransferase expression is regulated by general control of amino acid biosynthesis
uniprot|Q701Q9 Kluyveromyces lactis KLLA0F10043g jen2 Carboxylic acid permease
highly similar to uniprot|P06738 Saccharomyces cerevisiae YPR160W GPH1 Non-essential glycogen phosphorylase required for the mobilization of glycogen activity is regulated by cyclic AMP-mediated phosphorylation expression is regulated by stress-response elements and by the HOG MAP kinase pathway
similar to uniprot|P53091 Saccharomyces cerevisiae YGL201C MCM6 Protein involved in DNA replication component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex
weakly similar to uniprot|Q00947 Saccharomyces cerevisiae YDR463W STP1 Transcription factor activated by proteolytic processing in response to signals from the SPS sensor system for external amino acids activates transcription of amino acid permease genes and may have a role in tRNA processing
similar to uniprot|Q03697 Saccharomyces cerevisiae YML038C YMD8
similar to uniprot|P25654 Saccharomyces cerevisiae YCR090C Hypothetical ORF
similar to uniprot|P15891 Saccharomyces cerevisiae YCR088W ABP1 Actin-binding protein of the cortical actin cytoskeleton important for activation of the Arp2/3 complex that plays a key role actin in cytoskeleton organization
similar to uniprot|P37263 Saccharomyces cerevisiae YCR087C-A Hypothetical ORF
similar to uniprot|P25651 Saccharomyces cerevisiae YCR086W CSM1 Protein that forms a complex with Lrs4p located in the nucleolus Lrs4p-Csm1p heterodimer binds to Mam1p at kinetochores during meiosis I to mediate accurate chromosome segregation may be involved in premeiotic DNA replication
uniprot|P56094 Kluyveromyces lactis KLLA0F10263g TUP1 Transcriptional repressor TUP1
similar to uniprot|P32377 Saccharomyces cerevisiae YNR043W MVD1 Mevalonate pyrophosphate decarboxylase essential enzyme involved in the biosynthesis of isoprenoids and sterols including ergosterol acts as a homodimer
similar to uniprot|P32378 Saccharomyces cerevisiae YNR041C COQ2 Para hydroxybenzoate: polyprenyl transferase catalyzes the second step in ubiquinone (coenzyme Q) biosynthesis
similar to uniprot|Q751D6 Ashbya gossypii AGL230C AGL230Cp and weakly similar to YNR040W uniprot|P53736 Saccharomyces cerevisiae YNR040W Hypothetical ORF
similar to uniprot|P25372 Saccharomyces cerevisiae YCR083W TRX3 mitochondrial thioredoxin
some similarities with uniprot|P38141 Saccharomyces cerevisiae YBR240C THI2 Zinc finger protein of the Zn(II)2Cys6 type probable transcriptional activator of thiamine biosynthetic genes
similar to uniprot|P46672 Saccharomyces cerevisiae YGL105W ARC1 Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases (Mes1p and Gus1p) delivering tRNA to them stimulating catalysis and ensuring their localization to the cytoplasm also binds quadruplex nucleic acids
similar to uniprot|P38140 Saccharomyces cerevisiae YBR239C Hypothetical ORF
highly similar to uniprot|P53141 Saccharomyces cerevisiae YGL106W MLC1 Essential light chain for myosin Myo2p may stabilize Myo2p by binding to the neck region may interact with Myo1p Iqg1p and Myo2p to coordinate formation and contraction of the actomyosin ring with targeted membrane deposition
similar to uniprot|P38330 Saccharomyces cerevisiae YBR238C Hypothetical ORF
similar to uniprot|P53139 Saccharomyces cerevisiae YGL108C Protein of unknown function
similar to uniprot|Q754U8 Ashbya gossypii AFL027C PRP5 Pre-mRNA-processing ATP-dependent RNA helicase PRP5 and weakly similar to YBR237W uniprot|P21372 Saccharomyces cerevisiae PRP5 RNA helicase in the DEAD-box family
similar to uniprot|P32783 Saccharomyces cerevisiae YBR236C ABD1 Methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to the GpppN terminus of capped mRNA
similar to uniprot|P38329 Saccharomyces cerevisiae YBR235W Hypothetical ORF
similar to uniprot|P53137 Saccharomyces cerevisiae YGL110C CUE3 Protein of unknown function has a CUE domain that binds ubiquitin which may facilitate intramolecular monoubiquitination
similar to uniprot|P53136 Saccharomyces cerevisiae YGL111W NSA1 Constituent of 66S pre-ribosomal particles involved in 60S ribosomal subunit biogenesis
highly similar to uniprot|Q754U3 Ashbya gossypii AFL022W AFL022Wp and similar to YBR234C uniprot|P38328 Saccharomyces cerevisiae YBR234C ARC40 Essential subunit of the ARP2/3 complex which is required for the motility and integrity of cortical actin patches
similar to uniprot|P69850 Saccharomyces cerevisiae YBR233W-A DAD3 Essential protein component of the DASH complex involved in spindle integrity and kinetochore function interacts with Duo1p and Dam1p localizes to intranuclear spindles and kinetochore
similar to uniprot|P53040 Saccharomyces cerevisiae YGL112C TAF6 Subunit (60 kDa) of TFIID and SAGA complexes
weakly similar to uniprot|P53135 Saccharomyces cerevisiae YGL113W SLD3 Protein that interacts with Cdc45p in initiation of DNA replication gene exhibits synthetic lethality with dpb11-1
similar to uniprot|P38151 Saccharomyces cerevisiae YBR233W
similar to uniprot|P38326 Saccharomyces cerevisiae YBR231C SWC5 Protein of unknown function, component of the Swr1p complex that incorporates Htz1p into chromatin
similar to uniprot|P53134 Saccharomyces cerevisiae YGL114W Putative member of the oligopeptide transporter (OPT) family of membrane transporters
uniprot|Q9P869 Kluyveromyces lactis Nuclear protein SNF4
similar to uniprot|P26309 Saccharomyces cerevisiae YGL116W CDC20 Cell-cycle regulated activator of anaphase-promoting complex/cyclosome (APC/C) which is required for metaphase/anaphase transition directs ubiquitination of mitotic cyclins Pds1p and other anaphase inhibitors potential Cdc28p substrate
similar to uniprot|P53095 Saccharomyces cerevisiae YGL196W Hypothetical ORF
weakly similar to uniprot|P40449 Saccharomyces cerevisiae YIL161W Hypothetical ORF
similar to uniprot|P27796 Saccharomyces cerevisiae YIL160C POT1 3-ketoacyl-CoA thiolase with broad chain length specificity cleaves 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA during beta-oxidation of fatty acids
some similarities with uniprot|P40450 Saccharomyces cerevisiae YIL159W BNR1 Formin nucleates the formation of linear actin filaments involved in cell processes such as budding and mitotic spindle orientation which require the formation of polarized actin cables functionally redundant with BNI1
weakly similar to uniprot|P36169 Saccharomyces cerevisiae YKR100C SKG1 Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and bud
similar to uniprot|P40452 Saccharomyces cerevisiae YIL157C FMP35 The authentic non-tagged protein was localized to the mitochondria
highly similar to uniprot|Q2V2P4 Saccharomyces cerevisiae YIL156W-B
similar to uniprot|P22035 Saccharomyces cerevisiae YKR099W BAS1 Myb-related transcription factor involved in regulating basal and induced expression of genes of the purine and histidine biosynthesis pathways
similar to uniprot|Q02724 Saccharomyces cerevisiae YPL020C ULP1 Ubl (ubiquitin-like protein)-specific protease that cleaves Smt3p protein conjugates specifically required for cell cycle progression associates with nucleoporins and may interact with septin rings during telophase
similar to uniprot|P40965 Saccharomyces cerevisiae YFL003C MSH4 Protein involved in meiotic recombination required for normal levels of crossing over colocalizes with Zip2p to discrete foci on meiotic chromosomes has homology to bacterial MutS protein
similar to uniprot|P53686 Saccharomyces cerevisiae YPL015C HST2 Cytoplasmic member of the silencing information regulator 2 (Sir2) family of NAD()-dependent protein deacetylases modulates nucleolar (rDNA) and telomeric silencing possesses NAD()-dependent histone deacetylase activity in vitro
weakly similar to uniprot|P53918 Saccharomyces cerevisiae YNL125C ESBP6 Protein with similarity to monocarboxylate permeases appears not to be involved in transport of monocarboxylates such as lactate pyruvate or acetate across the plasma membrane
weakly similar to uniprot|P40960 Saccharomyces cerevisiae YDR488C PAC11 Dynein intermediate chain acts in the cytoplasmic dynein pathway forms cortical cytoplasmic microtubule capture site with Num1p null mutant is defective in nuclear migration essential in the absence of CIN8
similar to uniprot|Q6Q558 Saccharomyces cerevisiae YDR489W SLD5 Subunit of the GINS complex (Sld5p Psf1p Psf2p Psf3p) which binds to DNA replication origins and facilitates assembly of the DNA replication machinery
similar to uniprot|P22216 Saccharomyces cerevisiae YPL153C RAD53 Protein kinase required for cell-cycle arrest in response to DNA damage activated by trans autophosphorylation when interacting with hyperphosphorylated Rad9p
similar to uniprot|Q08650 Saccharomyces cerevisiae YOR245C DGA1 Diacylglycerol acyltransferase catalyzes the terminal step of triacylglycerol (TAG) formation acylates diacylglycerol using acyl-CoA as an acyl donor localized to lipid particles
similar to uniprot|Q12461 Saccharomyces cerevisiae YPL152W RRD2 Resistant to Rapamycin Deletion 2; similar to hosphotyrosyl phosphatase activator (PTPA) from several organisms
highly similar to uniprot|Q08649 Saccharomyces cerevisiae YOR244W ESA1 Histone acetyltransferase catalytic subunit of the native multisubunit complex (NuA4) that acetylates four conserved internal lysines of histone H4 N-terminal tail required for cell cycle progression
similar to uniprot|Q12417 Saccharomyces cerevisiae YPL151C PRP46 Splicing factor that is found in the Cef1p subcomplex of the spliceosome
similar to uniprot|Q08647 Saccharomyces cerevisiae YOR243C PUS7 pseudouridylates U2 snRNA at position 35
weakly similar to uniprot|Q96US5 Saccharomyces cerevisiae YOR242C SSP2 Sporulation SPecific involved in sporulation
similar to uniprot|Q08645 Saccharomyces cerevisiae YOR241W MET7 Folylpolyglutamate synthetase catalyzes extension of the glutamate chains of the folate coenzymes required for methionine synthesis and for maintenance of mitochondrial DNA present in both the cytoplasm and mitochondria
similar to uniprot|Q12152 Saccharomyces cerevisiae YPL150W Hypothetical ORF
similar to uniprot|Q12380 Saccharomyces cerevisiae YPL149W ATG5 Conserved autophagy-related protein that undergoes conjugation with Atg12p and then associates with Atg16p to form a cytosolic complex essential for autophagosome formation
similar to uniprot|Q08641 Saccharomyces cerevisiae YOR239W/YOR240W
weakly similar to uniprot|Q12036 Saccharomyces cerevisiae YPL148C PPT2 Phosphopantetheine:protein transferase (PPTase) activates mitochondrial acyl carrier protein (Acp1p) by phosphopantetheinylation
similar to uniprot|P41909 Saccharomyces cerevisiae YPL147W PXA1 Pxa1p and Pxa2p appear to be subunits of a peroxisomal ATP-binding cassette transporter necessary for transport of long-chain fatty acids into peroxisomes ABC family long-chain fatty acid transporter
similar to uniprot|Q75BZ3 Ashbya gossypii ACR126W ACR126Wp and some similarites with YPL146C uniprot|Q12080 Saccharomyces cerevisiae YPL146C NOP53 Nucleolar protein involved in biogenesis of the 60S subunit of the ribosome interacts with rRNA processing factors Cbf5p and Nop2p null mutant is viable but growth is severely impaired
weakly similar to uniprot|P17629 Saccharomyces cerevisiae YDR138W
some similarites with uniprot|Q12500 Saccharomyces cerevisiae YLR114C AVL9 PHO85 Requiring
weakly similar to uniprot|P16664 Saccharomyces cerevisiae YDR137W RGP1 Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleotide exchange on Ypt6p
similar to uniprot|P38247 Saccharomyces cerevisiae YBR077C SLM4 Protein with a potential role in actin cytoskeleton organization possible component of the TOR nutrient signaling pathway gene exhibits synthetic genetic interaction with MSS4 encoding phosphatidylinositol 4-phosphate kinase
some similarities with uniprot|P32325 Saccharomyces cerevisiae YDR052C DBF4 Regulatory subunit of Cdc7p-Dbf4p kinase complex
weakly similar to uniprot|Q6Q5F4 Saccharomyces cerevisiae YPR015C Hypothetical ORF
similar to uniprot|Q750Z5 Ashbya gossypii AGL208C AGL208Cp and some similarites with YNR067C uniprot|P53753 Saccharomyces cerevisiae
similar to uniprot|P38244 Saccharomyces cerevisiae YBR074W Hypothetical ORF
highly similar to uniprot|P32347 Saccharomyces cerevisiae YDR047W HEM12 Uroporphyrinogen decarboxylase catalyzes the fifth step in the heme biosynthetic pathway localizes to both the cytoplasm and nucleus activity inhibited by Cu2 Zn2 Fe2 Fe3 and sulfhydryl-specific reagents
similar to uniprot|Q66RH0 Saccharomyces cerevisiae YDR049W Hypothetical ORF
similar to uniprot|P38086 Saccharomyces cerevisiae YBR073W RDH54 DNA-dependent ATPase stimulates strand exchange by modifying the topology of double-stranded DNA involved in the recombinational repair of double-strand breaks in DNA during mitosis and meiosis proposed to be involved in crossover interference
weakly similar to uniprot|Q04549 Saccharomyces cerevisiae YDR106W ARP10 Actin-related protein
similar to uniprot|Q12116 Saccharomyces cerevisiae YDR105C TMS1 Putative membrane protein conserved in mammals
highly similar to uniprot|P25453 Saccharomyces cerevisiae YER179W DMC1 Meiosis-specific protein required for repair of double-strand breaks and pairing between homologous chromosomes homolog of Rad51p and the bacterial RecA protein
uniprot|Q6CKB6 Kluyveromyces lactis KLLA0F11979g ARX1 Probable metalloprotease ARX1
uniprot|O13366 Kluyveromyces lactis KLLA0F12001g PDA1 Pyruvate dehydrogenase E1 component alpha subunit, mitochondrial precursor
some similarities with uniprot|P32917 Saccharomyces cerevisiae YDR103W STE5 Scaffold protein that in response to pheromone shuttles from the nucleus to the plasma membrane and assembles kinases Ste11p Ste7p and Fus3p into a specific signaling complex active oligomeric form interacts with Ste4p-Ste18p complex
similar to uniprot|Q03868 Saccharomyces cerevisiae YDR104C SPO71 Meiosis-specific protein of unknown function required for spore wall formation during sporulation dispensable for both nuclear divisions during meiosis
similar to uniprot|P36156 Saccharomyces cerevisiae YKR076W
weakly similar to uniprot|Q03860 Saccharomyces cerevisiae YDR100W TVP15 Tlg2-Vesicle Protein of 15 kDa; integral membrane vesicle protein
highly similar to uniprot|P29311 Saccharomyces cerevisiae YER177W BMH1 14-3-3 protein major isoform binds proteins and DNA involved in regulation of many processes including exocytosis and vesicle transport Ras/MAPK signaling during pseudohyphal development rapamycin-sensitive signaling and others
similar to uniprot|Q06554 Saccharomyces cerevisiae YLR247C Hypothetical ORF
some similarities with uniprot|P38623 Saccharomyces cerevisiae YLR248W RCK2 Protein kinase involved in the response to oxidative stress identified as suppressor of S. pombe cell cycle checkpoint mutations
highly similar to uniprot|P16521 Saccharomyces cerevisiae YLR249W YEF3 stimulates the binding of aminoacyl-tRNA (AA-tRNA) to ribosomes by releasing EF-1 alpha from the ribosomal complex contains two ABC cassettes and binds and hydrolyses ATP EF-3 (translational elongation factor 3)
similar to uniprot|P53541 Saccharomyces cerevisiae YNL012W
similar to uniprot|P39931 Saccharomyces cerevisiae YLR250W SSP120 Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
similar to uniprot|P53980 Saccharomyces cerevisiae YNL011C Hypothetical ORF
similar to uniprot|P53981 Saccharomyces cerevisiae YNL010W Hypothetical ORF
highly similar to uniprot|P41939 Saccharomyces cerevisiae YLR174W IDP2 Cytosolic NADP-specific isocitrate dehydrogenase catalyzes oxidation of isocitrate to alpha-ketoglutarate levels are elevated during growth on non-fermentable carbon sources and reduced during growth on glucose
highly similar to uniprot|P25605 Saccharomyces cerevisiae YCL009C ILV6 Regulatory subunit of acetolactate synthase which catalyzes the first step of branched-chain amino acid biosynthesis enhances activity of the Ilv2p catalytic subunit localizes to mitochondria
mitochondrial 54S ribosomal protein YmL2
uniprot|P48535 Kluyveromyces lactis RM02 60S RIBOSOMAL PROTEIN L2, MITOCHONDRIAL PRECURSOR
similar to uniprot|P25554 Saccharomyces cerevisiae YCL010C SGF29 SaGa associated Factor 29kDa Probable 29kKDa Subunit of SAGA histone acetyltransferase complex
similar to uniprot|P33892 Saccharomyces cerevisiae YGL195W GCN1 Positive regulator of the Gcn2p kinase activity forms a complex with Gcn20p proposed to stimulate Gcn2p activation by an uncharged tRNA
some similarities with uniprot|P53094 Saccharomyces cerevisiae YGL197W MDS3 Protein with an N-terminal kelch-like domain putative negative regulator of early meiotic gene expression required with Pmd1p for growth under alkaline conditions
similar to uniprot|P53093 Saccharomyces cerevisiae YGL198W YIP4 Protein that interacts with Rab GTPases computational analysis of large-scale protein-protein interaction data suggests a possible role in vesicle-mediated transport
highly similar to uniprot|P32598 Saccharomyces cerevisiae YER133W GLC7 Catalytic subunit of type 1 serine/threonine protein phosphatase involved in many processes including glycogen metabolism sporulation and mitosis interacts with multiple regulatory subunits predominantly isolated with Sds22p
highly similar to uniprot|P32803 Saccharomyces cerevisiae YGL200C EMP24 Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles which function in ER to Golgi transport
similar to uniprot|P38204 Saccharomyces cerevisiae YBL025W RRN10 subunit of UAF (upstream activation factor) involved in promoting high level transcription of rDNA Upstream activation factor subunit
highly similar to uniprot|P38205 Saccharomyces cerevisiae YBL024W
highly similar to uniprot|P29469 Saccharomyces cerevisiae YBL023C MCM2 Protein involved in DNA replication component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex
similar to uniprot|P38067 Saccharomyces cerevisiae YBR006w UGA2 succinate semialdehyde dehydrogenase involved in the utilization of gamma-aminobutyrate (GABA) as a nitrogen source
similar to uniprot|P40085 Saccharomyces cerevisiae YER140W Hypothetical ORF
similar to uniprot|P40084 Saccharomyces cerevisiae YER139C Hypothetical ORF
weakly similar to uniprot|Q6Q5U4 Saccharomyces cerevisiae YDR065W Hypothetical ORF
highly similar to uniprot|P00890 Saccharomyces cerevisiae YNR001C CIT1 Citrate synthase catalyzes the condensation of acetyl coenzyme A and oxaloacetate to form citrate the rate-limiting enzyme of the TCA cycle nuclear encoded mitochondrial protein
similar to uniprot|P25349 Saccharomyces cerevisiae YCR004C YCP4 Protein of unknown function, has sequence and structural similarity to flavodoxins; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
mitochondrial 54S ribosomal protein YmL32
similar to uniprot|P25348 Saccharomyces cerevisiae YCR003W MRPL32 Mitochondrial ribosomal protein of the large subunit
highly similar to uniprot|P25342 Saccharomyces cerevisiae YCR002C CDC10 Component of the septin ring of the mother-bud neck that is required for cytokinesis septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane and they comprise the 10nm filaments seen with EM
highly similar to uniprot|P54861 Saccharomyces cerevisiae YLL001W DNM1 Dynamin-related GTPase required for mitochondrial fission and the maintenance of mitochondrial morphology assembles on the cytoplasmic face of mitochondrial tubules at sites at which division will occur also participates in endocytosis
similar to uniprot|Q07794 Saccharomyces cerevisiae YLL002W RTT109 Regulator of Ty1 Transposition Regulation of mitochondrial network Killed in Mutagen sensitive to diepoxybutane and/or mitomycin C diepoxybutane and mitomycin C resistance
highly similar to uniprot|P38624 YJL001W Saccharomyces cerevisiae PRE3 20S proteasome beta-type subunit
weakly similar to uniprot|Q12369 Saccharomyces cerevisiae YLL003W SFI1
similar to uniprot|P41543 Saccharomyces cerevisiae YJL002C OST1 Alpha subunit of the oligosaccharyltransferase complex of the ER lumen which catalyzes asparagine-linked glycosylation of newly synthesized proteins
similar to uniprot|P54790 Saccharomyces cerevisiae YLL004W ORC3 Subunit of the origin recognition complex which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing
highly similar to uniprot|P47081 Saccharomyces cerevisiae YJL003W COX16 Mitochondrial inner membrane protein required for assembly of cytochrome c oxidase
weakly similar to uniprot|P07248 Saccharomyces cerevisiae YDR216W ADR1 Positive transcriptional regulator controls the expression of ADH2 peroxisomal protein genes and genes required for ethanol glycerol and fatty acid utilization
weakly similar to uniprot|P14737 Saccharomyces cerevisiae YDR217C RAD9 DNA damage-dependent checkpoint protein required for cell-cycle arrest in G1/S intra-S and G2/M transmits checkpoint signal by activating Rad53p and Chk1p hyperphosphorylated by Mec1p and Tel1p potential Cdc28p substrate
some similarities with uniprot|Q05955 Saccharomyces cerevisiae YLR227C ADY4 Component of the meiotic outer plaque
similar to uniprot|Q04921 Saccharomyces cerevisiae YDR218C SPR28 Septin-related protein expressed during sporulation
similar to uniprot|Q05949 Saccharomyces cerevisiae YLR226W BUR2 Cyclin for the Sgv1p (Bur1p) protein kinase Sgv1p and Bur2p comprise a CDK-cyclin complex involved in transcriptional regulation through its phosphorylation of the carboxy-terminal domain of the largest subunit of RNA polymerase II
some similarities with uniprot|Q04922 Saccharomyces cerevisiae YDR219C Hypothetical ORF
weakly similar to uniprot|Q04924 Saccharomyces cerevisiae YDR221W Hypothetical ORF
similar to uniprot|Q04925 YDR222W Saccharomyces cerevisiae Protein of unknown function
weakly similar to uniprot|P39520 Saccharomyces cerevisiae YLR223C IFH1 Essential protein with a highly acidic N-terminal domain IFH1 exhibits genetic interactions with FHL1 overexpression interferes with silencing at telomeres and HM loci potential Cdc28p substrate
highly similar to uniprot|Q05946 Saccharomyces cerevisiae YLR222C UTP13 Nucleolar protein component of the small subunit (SSU) processome containing the U3 snoRNA
weakly similar to uniprot|Q05942 Saccharomyces cerevisiae YLR221C RSA3 Protein with a likely role in ribosomal maturation required for accumulation of wild-type levels of large (60S) ribosomal subunits binds to the helicase Dbp6p in pre-60S ribosomal particles in the nucleolus
similar to uniprot|P47818 Saccharomyces cerevisiae YLR220W CCC1 Functions in the homeostasis of both calcium and manganese ions Possible transmembrane Ca2 transporter
similar to uniprot|P02293 Saccharomyces cerevisiae YDR224C HTB1 One of two nearly identical (see HTB2) histone H2B subtypes required for chromatin assembly and chromosome function Rad6p-Bre1p-Lge1p mediated ubiquitination regulates transcriptional activation meiotic DSB formation and H3 methylation and similar to YBL002W uniprot|P02294 Saccharomyces cerevisiae YBL002W HTB2 One of two nearly identical (see HTB2) histone H2B subtypes required for chromatin assembly and chromosome function; Rad6p-Bre1p-Lge1p mediated ubiquitination regulates transcriptional activation, meiotic DSB formation and H3 methylation
similar to uniprot|P04911 Saccharomyces cerevisiae YDR225W HTA1 One of two nearly identical (see also HTA2) histone H2A subtypes core histone required for chromatin assembly and chromosome function DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair acetylated by Nat4p and similar to YBL003C uniprot|P04912 Saccharomyces cerevisiae YBL003C HTA2 One of two nearly identical (see also HTA1) histone H2A subtypes; core histone required for chromatin assembly and chromosome function; DNA damage- dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p
weakly similar to uniprot|Q7LIF4 Saccharomyces cerevisiae YLR219W MSC3 Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cell periphery msc3 mutants are defective in directing meiotic recombination events to homologous chromatids potential Cdc28p substrate
highly similar to uniprot|P07170 Saccharomyces cerevisiae YDR226W ADK1 adenylate kinase
uniprot|O59904 Kluyveromyces lactis SIR4 Silent information regulator 4
similar to uniprot|P39081 Saccharomyces cerevisiae YDR228C PCF11 mRNA 3' end processing factor essential component of cleavage and polyadenylation factor IA (CF IA) involved in pre-mRNA 3' end processing and in transcription termination binds C-terminal domain of largest subunit of RNA pol II (Rpo21p)
highly similar to uniprot|P38988 Saccharomyces cerevisiae YDL198C GGC1 Mitochondrial GTP/GDP transporter essential for mitochondrial genome maintenance has a role in mitochondrial iron transport member of the mitochondrial carrier family (putative) mitochondrial carrier protein
some similarities with uniprot|P34246 Saccharomyces cerevisiae YKL098W Hypothetical ORF
similar to uniprot|P34247 Saccharomyces cerevisiae YKL099C UTP11 Nucleolar protein component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
uniprot|P49385 Kluyveromyces lactis ADH4 Alcohol dehydrogenase IV, mitochondrial precursor
weakly similar to uniprot|P34244 Saccharomyces cerevisiae YKL101W HSL1 Nim1p-related protein kinase that regulates the morphogenesis and septin checkpoints associates with the assembled septin filament required along with Hsl7p for bud neck recruitment phosphorylation and degradation of Swe1p
similar to uniprot|P14904 YKL103C Saccharomyces cerevisiae LAP4 Vacuolar aminopeptidase
highly similar to uniprot|P14742 Saccharomyces cerevisiae YKL104C GFA1 Glutamine-fructose-6-phosphate amidotransferase catalyzes the formation of glucosamine-6-P and glutamate from fructose-6-P and glutamine in the first step of chitin biosynthesis
some similarities with uniprot|Q04279 Saccharomyces cerevisiae YMR086W Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and uniprot|P34250 Saccharomyces cerevisiae YKL105C
similar to uniprot|Q01802 Saccharomyces cerevisiae YKL106W AAT1 Mitochondrial aspartate aminotransferase catalyzes the conversion of oxaloacetate to aspartate in aspartate and asparagine biosynthesis
similar to uniprot|Q04299 Saccharomyces cerevisiae YMR087W Putative ADP-ribose-1''-monophosphatase that converts ADP-ribose-1''-monophosphate to ADP-ribose may have a role in tRNA splicing contains an A1pp domain
similar to uniprot|Q04301 Saccharomyces cerevisiae YMR088C VBA1 Permease of basic amino acids in the vacuolar membrane
similar to uniprot|P40341 Saccharomyces cerevisiae YMR089C YTA12 Component with Afg3p of the mitochondrial inner membrane m-AAA protease that mediates degradation of misfolded or unassembled proteins and is also required for correct assembly of mitochondrial enzyme complexes
similar to uniprot|P32832 Saccharomyces cerevisiae YMR091C NPL6 Nuclear protein that may have a role in nuclear protein import
similar to uniprot|P46680 Saccharomyces cerevisiae YMR092C AIP1 Actin cortical patch component probable binding site on actin lies on front surface of subdomains 3 and 4
highly similar to uniprot|Q04305 Saccharomyces cerevisiae YMR093W UTP15 Nucleolar protein component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
similar to uniprot|Q75DR2 Ashbya gossypii ABL045W and weakly similar to YKL108W uniprot|P34252 Saccharomyces cerevisiae SLD2 Protein required for DNA replication
weakly similar to uniprot|P35203 Saccharomyces cerevisiae YMR094W CTF13 Subunit of the CBF3 complex which binds to the CDE III element of centromeres bending the DNA upon binding and may be involved in sister chromatid cohesion during mitosis
uniprot|O94233 Kluyveromyces lactis HAP4
similar to uniprot|P42949 Saccharomyces cerevisiae YJL104W
similar to uniprot|P36119 Saccharomyces cerevisiae YKR023W Hypothetical ORF
similar to uniprot|P42950 Saccharomyces cerevisiae YJL103C Hypothetical ORF
similar to uniprot|P36120 Saccharomyces cerevisiae YKR024C DBP7 Putative ATP-dependent RNA helicase of the DEAD-box family involved in ribosomal biogenesis
similar to uniprot|P36121 Saccharomyces cerevisiae YKR025W RPC37 RNA polymerase III subunit C37
highly similar to uniprot|P14741 Saccharomyces cerevisiae YKR026C GCN3 Alpha subunit of the translation initiation factor eIF2B the guanine-nucleotide exchange factor for eIF2
similar to uniprot|P39677 Saccharomyces cerevisiae YJL102W MEF2 mitochondrial elongation factor G-like protein
similar to uniprot|P32477 Saccharomyces cerevisiae YJL101C GSH1 Gamma glutamylcysteine synthetase catalyzes the first step in the gamma-glutamyl cycle for glutathione (GSH) biosynthesis expression induced by oxidants cadmium and mercury
similar to uniprot|P42951 Saccharomyces cerevisiae YJL100W LSB6 Phosphatidylinositol 4-kinase that binds Las17p which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization
similar to uniprot|P36122 Saccharomyces cerevisiae YKR027W FMP50 The authentic non-tagged protein was localized to the mitochondria and uniprot|P40955 Saccharomyces cerevisiae YJL099w CHS6 chitin biosynthesis protein
similar to uniprot|P36123 Saccharomyces cerevisiae or to YJL098W uniprot|P40856 Saccharomyces cerevisiae YJL098W
similar to uniprot|P40857 Saccharomyces cerevisiae YJL097W Protein required for cell viability
mitochondrial 54S ribosomal protein YmL49
some similarities with uniprot|P40858 Saccharomyces cerevisiae YJL096W MRPL49 Mitochondrial ribosomal protein of the large subunit
uniprot|O60030 Kluyveromyces lactis BCK1 MAP kinase kinase kinase
weakly similar to uniprot|P40310 Saccharomyces cerevisiae YJL093C TOK1 Target Of K1 Killer Toxin outward-rectifier potassium channel
similar to uniprot|P12954 Saccharomyces cerevisiae YJL092W HPR5 DNA helicase and DNA-dependent ATPase involved in DNA repair required for proper timing of commitment to meiotic recombination and the transition from Meiosis I to Meiosis II potential Cdc28p substrate
similar to uniprot|P47026 Saccharomyces cerevisiae YJL091C GWT1 Protein involved in the inositol acylation of glucosaminyl phosphatidylinositol (GlcN-PI) to form glucosaminyl(acyl)phosphatidylinositol (GlcN(acyl)PI) an intermediate in the biosynthesis of glycosylphosphatidylinositol (GPI) anchors
similar to uniprot|P47027 Saccharomyces cerevisiae YJL090C DPB11 Essential BRCT repeat protein required on the prereplicative complex at replication origins for loading DNA polymerases to initiate DNA synthesis also required for S/M checkpoint control
uniprot|Q7Z8R2 Kluyveromyces lactis Sip4 protein
weakly similar to uniprot|P36118 Saccharomyces cerevisiae YKR022C Protein required for cell viability
similar to uniprot|P05150 YJL088W Saccharomyces cerevisiae ARG3 Ornithine carbamoyltransferase
similar to uniprot|P09880 YJL087C Saccharomyces cerevisiae TRL1 tRNA ligase
similar to uniprot|P19658 YJL085W Saccharomyces cerevisiae EXO70 Essential 70kDa subunit of the exocyst complex (Sec3p Sec5p Sec6p Sec8p Sec10p Sec15p Exo70p and Exo84p)
some similarities with uniprot|P47029 Saccharomyces cerevisiae YJL084C Cytoplasmic protein of unknown function that interacts with Pcl7p phosphorylated in vitro potential Cdc28p substrate
similar to uniprot|P14736 Saccharomyces cerevisiae YER162C RAD4 Protein that recognizes and binds damaged DNA (with Rad23p) during nucleotide excision repair subunit of Nuclear Excision Repair Factor 2 (NEF2) homolog of human XPC protein
weakly similar to uniprot|P06843 Saccharomyces cerevisiae YER161c SPT2 multifunctional HMG-like chromatin protein
similar to uniprot|P38966 Saccharomyces cerevisiae YDR089W Hypothetical ORF
weakly similar to uniprot|Q02775 Saccharomyces cerevisiae YDR088C SLU7 Protein involved in 3' splice site choices acts in concert with Prp18p during the 2nd step of splicing
similar to uniprot|P53294 Saccharomyces cerevisiae YGR169C PUS6 RNA:Psi-synthase and weakly similar to YOL066C uniprot|Q12362 Saccharomyces cerevisiae YOL066C RIB2 DRAP deaminase, catalyzes the third step of the riboflavin biosynthesis pathway; N-terminus has sequence similarity to RNA:pseudouridine synthases
some similarities with uniprot|P47068 Saccharomyces cerevisiae YJL020C/YJL021C BBC1 Protein possibly involved in assembly of actin patches
weakly similar to uniprot|P53293 Saccharomyces cerevisiae YGR168C Hypothetical ORF
similar to uniprot|P17891 Saccharomyces cerevisiae YGR167W CLC1 Clathrin light chain
weakly similar to uniprot|P32893 Saccharomyces cerevisiae YGR166W KRE11 Protein involved in biosynthesis of cell wall beta-glucans subunit of the TRAPP (transport protein particle) complex which is involved in the late steps of endoplasmic reticulum to Golgi transport
uniprot|P33294 Kluyveromyces lactis KLLA0F14663g SIR2 NAD-dependent histone deacetylase SIR2
similar to uniprot|P32607 Saccharomyces cerevisiae YOL067C RTG1 Transcription factor (bHLH) involved in interorganelle communication between mitochondria peroxisomes and nucleus
highly similar to uniprot|P40327 Saccharomyces cerevisiae YDL007W RPT2 One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates required for normal peptide hydrolysis by the core 20S particle
highly similar to uniprot|P35182 Saccharomyces cerevisiae YDL006W PTC1 Type 2C protein phosphatase (PP2C) inactivates the osmosensing MAPK cascade by dephosphorylating Hog1p mutation delays mitochondrial inheritance deletion reveals defects in precursor tRNA splicing sporulation and cell separation
weakly similar to uniprot|Q12124 Saccharomyces cerevisiae YDL005C MED2 RNA Polymerase II transcriptional regulation mediator Stoichiometric member of mediator complex
uniprot|P78700 Kluyveromyces lactis KLLA0F14773g ATP16 ATP synthase delta chain, mitochondrial precursor
similar to uniprot|Q12158 Saccharomyces cerevisiae YDL003W MCD1 Essential protein required for sister chromatid cohesion in mitosis and meiosis
similar to uniprot|Q05468 Saccharomyces cerevisiae YDR333C Hypothetical ORF
similar to uniprot|P38803 Saccharomyces cerevisiae YHR085W IPI1 Protein of unknown function essential for viability may be involved in rRNA processing
some similarities with uniprot|Q00539 Saccharomyces cerevisiae YHR086W NAM8 RNA binding protein component of the U1 snRNP protein
similar to uniprot|Q3E772 Saccharomyces cerevisiae YGR169C-A
weakly similar to uniprot|P53037 Saccharomyces cerevisiae YGR170W PSD2 Phosphatidylserine decarboxylase of the Golgi and vacuolar membranes converts phosphatidylserine to phosphatidylethanolamine
similar to uniprot|P46957 Saccharomyces cerevisiae YJR006W HYS2 DNA polymerase III (delta) 55 kDa subunit essential for cell viability involved in DNA replication and DNA repair
similar to uniprot|P22438 Saccharomyces cerevisiae YGR171C MSM1 Mitochondrial methionyl-tRNA synthetase (MetRS), functions as a monomer in mitochondrial protein synthesis; functions similarly to cytoplasmic MetRS although the cytoplasmic form contains a zinc-binding domain not found in Msm1p
highly similar to uniprot|P53295 Saccharomyces cerevisiae YGR173W
similar to uniprot|P53039 Saccharomyces cerevisiae YGR172C YIP1 Golgi integral membrane protein binds to the transport GTPases Ypt1p and Ypt31p
weakly similar to uniprot|P29509 Saccharomyces cerevisiae YDR353W TRR1 Thioredoxin reductase
highly similar to uniprot|P09938 Saccharomyces cerevisiae YJL026W RNR2 Ribonucleotide-diphosphate reductase (RNR) small subunit the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits
some similarities with uniprot|P53298 Saccharomyces cerevisiae YGR179C OKP1 Outer kinetochore protein required for accurate mitotic chromosome segregation forms a complex with Mcm21p and Okp1p that binds to centromeres via the CBF3 complex
similar to uniprot|P53297 Saccharomyces cerevisiae YGR178C PBP1 Protein interacting with poly(A)-binding protein Pab1p likely involved in control of the extent of mRNA polyadenylation
similar to uniprot|P40992 Saccharomyces cerevisiae YJL025W RRN7 involved in the transcription of 35S rRNA genes by RNA polymerase I member of yeast Pol I core factor (CF) also composed of Rrn11p Rrn6p and TATA-binding protein
similar to uniprot|P53296 Saccharomyces cerevisiae YGR177C ATF2 Alcohol acetyltransferase may play a role in steroid detoxification forms volatile esters during fermentation which is important in brewing
highly similar to uniprot|P32476 Saccharomyces cerevisiae YGR175C ERG1 Squalene epoxidase catalyzes the epoxidation of squalene to 2 3-oxidosqualene plays an essential role in the ergosterol-biosynthesis pathway and is the specific target of the antifungal drug terbinafine
similar to uniprot|P37267 Saccharomyces cerevisiae YGR174C CBP4 Essential for the expression and activity of ubiquinol-cytochrome c reductase ubiquinol--cytochrome-c reductase assembly factor
similar to uniprot|P47064 Saccharomyces cerevisiae YJL024C APS3 Small subunit of the clathrin-associated adaptor complex AP-3 which is involved in vacuolar protein sorting related to the sigma subunit of the mammalian clathrin AP-3 complex suppressor of loss of casein kinase 1 function
similar to uniprot|P53299 Saccharomyces cerevisiae YGR181W TIM13 Translocase of the inner membrane mitochondrial intermembrane space protein mediating import and insertion of polytopic inner membrane proteins Subunit of mitochondrial protein import machinery
similar to uniprot|P22289 Saccharomyces cerevisiae YGR183C QCR9 7.3 kDa subunit 9 of the ubiquinol cytochrome c oxidoreductase complex
uniprot|O60014 Kluyveromyces lactis UBR1 N-END-RECOGNIZING PROTEIN (UBIQUITIN-PROTEIN LIGASE E3 COMPONENT) (N-RECOGNIN)
similar to uniprot|Q07963 Saccharomyces cerevisiae YLR024C UBR2 Cytoplasmic ubiquitin-protein ligase (E3)
highly similar to uniprot|P36421 Saccharomyces cerevisiae YGR185C TYS1 tyrosyl-tRNA synthetase cytoplasmic
similar to uniprot|P41895 Saccharomyces cerevisiae YGR186W TFG1 Largest subunit of the RNA Polymerase general transcription factor IIF (TFIIF) interacts with Fcp1p phosphatase and with TFIIB potentially phosphorylated by Cdc28p
similar to uniprot|P48362 Saccharomyces cerevisiae YGR187C
similar to uniprot|Q12431 Saccharomyces cerevisiae YLL014W Hypothetical ORF
some similarities with uniprot|Q02601 Saccharomyces cerevisiae YLL013C PUF3 member of the PUF protein family which is named for the founding members PUmilio and Fbf
some similarities with uniprot|Q07959 Saccharomyces cerevisiae YLR023C IZH3 Membrane protein involved in zinc metabolism member of the four-protein IZH family expression induced by zinc deficiency deletion reduces sensitivity to elevated zinc and shortens lag phase overexpression reduces Zap1p activity
highly similar to uniprot|Q07953 Saccharomyces cerevisiae YLR022C SDO1 Protein required for cell viability
similar to uniprot|Q07951 Saccharomyces cerevisiae YLR021W Hypothetical ORF
similar to uniprot|Q07950 Saccharomyces cerevisiae YLR020C YEH2 Steryl ester hydrolase catalyzes steryl ester hydrolysis at the plasma membrane involved in sterol metabolism
highly similar to uniprot|P33750 Saccharomyces cerevisiae YLL011W
similar to uniprot|Q07800 Saccharomyces cerevisiae YLL010C
weakly similar to uniprot|Q7LGY6 Saccharomyces cerevisiae YLR018C POM34 nuclear pore integral membrane protein
highly similar to uniprot|Q07938 Saccharomyces cerevisiae YLR017W MEU1 Methylthioadenosine phosphorylase (MTAP) catalyzes the initial step in the methionine salvage pathway affects polyamine biosynthesis through regulation of ornithine decarboxylase (Spe1p) activity regulates ADH2 gene expression
some similarities with uniprot|Q12287 Saccharomyces cerevisiae YLL009C COX17 Copper metallochaperone that shuttles copper from the cytosol to the mitochondrial intermembrane space for delivery to cytochrome c oxidase
similar to uniprot|P08678 Saccharomyces cerevisiae YJL005W CYR1 Adenylate cyclase required for cAMP production and cAMP-dependent protein kinase signaling involved in cell cycle control and glucose and nitrogen repression of sporulation
similar to uniprot|P41544 Saccharomyces cerevisiae YJL004C SYS1 Multicopy suppressor of ypt6 null mutation
similar to uniprot|P32892 Saccharomyces cerevisiae YLL008W DRS1 Nucleolar DEAD-box protein required for ribosome assembly and function
weakly similar to uniprot|Q07799 Saccharomyces cerevisiae YLL007C Hypothetical ORF
similar to uniprot|P41800 Saccharomyces cerevisiae YLL006W MMM1 Mitochondrial outer membrane protein required for normal mitochondrial morphology and mtDNA stability involved in tethering mitochondria to the actin cytoskeleton and in anchoring mtDNA nucleoids
weakly similar to uniprot|Q07798 Saccharomyces cerevisiae YLL005C SPO75 Meiosis-specific protein of unknown function required for spore wall formation during sporulation dispensable for both nuclear divisions during meiosis
similar to uniprot|P31382 Saccharomyces cerevisiae YAL023C PMT2 Transfers mannosyl residues from dolichyl phosphate-D-mannose to seryl and threonyl residues in proteins acts in complex with Pmt1p dolichyl phosphate-D-mannose:protein O-D-mannosyltransferase
similar to uniprot|P31381 Saccharomyces cerevisiae YAL022C FUN26 Nucleoside transporter with broad nucleoside selectivity localized to intracellular membranes
similar to uniprot|P31384 Saccharomyces cerevisiae YAL021C CCR4 Component of the CCR4-NOT transcriptional complex which is involved in regulation of gene expression component of the major cytoplasmic deadenylase which is involved in mRNA poly(A) tail shortening
similar to uniprot|P31386 Saccharomyces cerevisiae YAL020C ATS1 Protein with a potential role in regulatory interactions between microtubules and the cell cycle as suggested by genetic and physical interactions with Nap1p and genetic interactions with TUB1
similar to uniprot|P35198 Saccharomyces cerevisiae YDR277C MTH1 Negative regulator of the glucose-sensing signal transduction pathway required for repression of transcription by Rgt1p interacts with Rgt1p and the Snf3p and Rgt2p glucose sensors phosphorylated by Yck1p triggering Mth1p degradation
similar to uniprot|P20449 Saccharomyces cerevisiae YOR046C DBP5 Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family involved in mRNA export from the nucleus
similar to uniprot|P33448 Saccharomyces cerevisiae YOR045W TOM6 involved in supporting the cooperativity between receptors and the general insertion pore and facilitating the release of preproteins from import components
similar to uniprot|P12611 Saccharomyces cerevisiae YOR043W WHI2 Protein required with binding partner Psr1p for full activation of the general stress response possibly through Msn2p dephosphorylation regulates growth during the diauxic shift negative regulator of G1 cyclin expression
similar to uniprot|Q08412 Saccharomyces cerevisiae YOR042W CUE5 Protein containing a CUE domain that binds ubiquitin which may facilitate intramolecular monoubiquitination green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
similar to uniprot|Q12320 Saccharomyces cerevisiae YOR040W GLO4 Mitochondrial glyoxalase II catalyzes the hydrolysis of S-D-lactoylglutathione into glutathione and D-lactate
similar to uniprot|P36052 Saccharomyces cerevisiae YKL162C Hypothetical ORF
similar to uniprot|Q08417 Saccharomyces cerevisiae YOR049C RSB1 Suppressor of sphingoid long chain base (LCB) sensitivity of an LCB-lyase mutation putative integral membrane transporter or flippase that may transport LCBs from the cytoplasmic side toward the extracytoplasmic side of the membrane
similar to uniprot|P36148 Saccharomyces cerevisiae YKR067W GPT2 Glycerol-3-phosphate acyltransferase located in both lipid particles and the ER involved in the stepwise acylation of glycerol-3-phosphate and dihydroxyacetone which are intermediate steps in lipid biosynthesis
highly similar to uniprot|P36149 Saccharomyces cerevisiae YKR068C BET3 Hydrophilic protein that acts in conjunction with SNARE proteins in targeting and fusion of ER to Golgi transport vesicles component of the TRAPP (transport protein particle) complex
similar to uniprot|Q6Q5I2 Saccharomyces cerevisiae YOR051C which is a model system for studying replication of positive-strand RNA viruses in their natural hosts
similar to uniprot|P36150 Saccharomyces cerevisiae YKR069W MET1 S-adenosyl-L-methionine uroporphyrinogen III transmethylase
similar to uniprot|P36151 Saccharomyces cerevisiae YKR070W Hypothetical ORF
some similarities with uniprot|O00017 Saccharomyces cerevisiae YOR052C
similar to uniprot|P36152 Saccharomyces cerevisiae YKR071C DRE2
weakly similar to uniprot|O00019 Saccharomyces cerevisiae YOR054C VHS3 Regulatory subunit of Ppz1p which is an isoform of serine/threonine protein phosphatase Z involved in regulation of potassium transport overexpression suppresses the synthetic lethality of the hal3 sit4 double mutation
similar to uniprot|O00021 Saccharomyces cerevisiae YOR056C NOB1 Nin1 (One) Binding protein essential nuclear protein involved in proteasome maturation and synthesis of 40S ribosome subunits required for cleavage of the 20S pre-rRNA to generate the mature 18S rRNA.
similar to uniprot|Q08446 Saccharomyces cerevisiae YOR057W SGT1 Probable cochaperone regulates activity of Cyr1p (adenylyl cyclase) involved in assembly of the kinetochore complex associates with the SCF (Skp1p/Cdc53p/F box protein) ubiquitin ligase complex
weakly similar to uniprot|P50275 Saccharomyces cerevisiae YOR058C ASE1 Member of a family of microtubule-associated proteins (MAPs) that function at the mitotic spindle midzone required for spindle elongation undergoes cell cycle-regulated degradation by anaphase promoting complex potential Cdc28p substrate
highly similar to uniprot|P36154 Saccharomyces cerevisiae YKR074W Hypothetical ORF
similar to uniprot|O00022 Saccharomyces cerevisiae YOR059C Hypothetical ORF
similar to uniprot|O00023 Saccharomyces cerevisiae YOR060C Protein required for cell viability
highly similar to uniprot|P19454 Saccharomyces cerevisiae YOR061W CKA2 alpha' subunit of casein kinase II
some similarities with uniprot|P36155 Saccharomyces cerevisiae or YOR062c uniprot|P36025 Saccharomyces cerevisiae
highly similar to uniprot|P14126 Saccharomyces cerevisiae YOR063W
weakly similar to uniprot|O00025 Saccharomyces cerevisiae YOR064C YNG1 Yeast homolog of mammalian Ing1 histone acetyltransferase complex component
uniprot|Q00988 Kluyveromyces lactis KLLA0F16555g CYT1 Cytochrome c1, heme protein, mitochondrial precursor
weakly similar to uniprot|O00026 Saccharomyces cerevisiae YOR066W Protein of unknown function potential Cdc28p substrate
highly similar to uniprot|P40351 Saccharomyces cerevisiae YOR067C ALG8 adds glucose to the dolichol-linked oligosaccharide precursor prior to transfer to protein glycosyl transferase
similar to uniprot|Q92331 Saccharomyces cerevisiae YOR069W VPS5 Component of the retromer coat that retrieves proteins from late endosomes sorting nexin I homolog
similar to uniprot|P36159 Saccharomyces cerevisiae YKR079C TRZ1 Protein required for cell viability
some similarities with uniprot|O00022 Saccharomyces cerevisiae YOR059C Hypothetical ORF
weakly similar to uniprot|P32613 Saccharomyces cerevisiae YEL048C Hypothetical ORF
similar to uniprot|P21375 Saccharomyces cerevisiae YJR051W OSM1 Fumarate reductase catalyzes the reduction of fumarate to succinate required for the reoxidation of intracellular NADH under anaerobic conditions mutations cause osmotic sensitivity
highly similar to uniprot|P37303 Saccharomyces cerevisiae YEL046C GLY1 Threonine aldolase catalyzes the cleavage of L-allo-threonine and L-threonine to glycine involved in glycine biosynthesis
similar to uniprot|P32617 Saccharomyces cerevisiae YEL044W IES6 Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions
uniprot|Q96WJ2 Kluyveromyces lactis PRM1 Paromomycin- resistance protein Prm1
similar to uniprot|P21374 Saccharomyces cerevisiae YJR050W ISY1 Component of the spliceosome complex involved in pre-mRNA splicing auxiliary splicing factor that may modulate Syf1p activity and help optimize splicing isy1 syf2 double mutation activates the spindle checkpoint causing cell cycle arrest
uniprot|Q9HEM6 Kluyveromyces lactis KLLA0F16863g GDA1 Guanosine-diphosphatase
highly similar to uniprot|P21373 Saccharomyces cerevisiae YJR049C UTR1 NAD kinase active as a hexamer enhances the activity of ferric reductase (Fre1p)
similar to uniprot|P32623 Saccharomyces cerevisiae YEL040W UTR2 Putative glycosidase glycosylphosphatidylinositol (GPI)-anchored protein localized to the bud neck has a role in cell wall maintenance
uniprot|P32556 Kluyveromyces lactis KLLA0F16929g CYCK Cytochrome c
uniprot|O74722 Kluyveromyces lactis PDC Pyruvate decarboxylase
uniprot|O60042 Kluyveromyces lactis GSK-3 Protein kinase
similar to uniprot|P32419 Saccharomyces cerevisiae YDL078C MDH3 Cytoplasmic malate dehydrogenase catalyzes interconversion of malate and oxaloacetate involved in the glyoxylate cycle
similar to uniprot|P39110 Saccharomyces cerevisiae YMR138W CIN4 GTP-binding protein involved in beta-tubulin (Tub2p) folding
similar to uniprot|Q759M6 Ashbya gossypii ADR250C ADR250Cp and weakly similar to YMR137C uniprot|P30620 Saccharomyces cerevisiae YMR137C PSO2 Required for a post-incision step in the repair of DNA single and double-strand breaks that result from interstrand crosslinks produced by a variety of mono- and bi-functional psoralen derivatives induced by UV-irradiation
weakly similar to uniprot|P40209 Saccharomyces cerevisiae YMR136W GAT2
similar to uniprot|Q759M8 Ashbya gossypii ADR248C ADR248Cp and weakly similar to YMR135C uniprot|P40208 Saccharomyces cerevisiae YMR135C GID8 Protein of unknown function involved in proteasome-dependent catabolite inactivation of fructose-1 6-bisphosphatase contains LisH and CTLH domains like Vid30p
similar to uniprot|P40207 Saccharomyces cerevisiae YMR134W Protein required for cell viability
some similarities with uniprot|Q07988 Saccharomyces cerevisiae YLR040C Hypothetical ORF
weakly similar to uniprot|P32841 Saccharomyces cerevisiae YMR133W REC114 Protein involved in early stages of meiotic recombination; possibly involved in the coordination of recombination and meiotic division; mutations lead to premature initiation of the first meiotic division
similar to uniprot|P40206 Saccharomyces cerevisiae YMR132C JLP2 Hypothetical ORF
highly similar to uniprot|Q04225 Saccharomyces cerevisiae YMR131C RRB1 essential nuclear protein involved in early steps of ribosome biogenesis
similar to uniprot|P40395 Saccharomyces cerevisiae YLR039C RIC1 Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleotide exchange on Ypt6p involved in transcription of ribosomal protein genes and ribosomal RNA
highly similar to uniprot|Q01519 Saccharomyces cerevisiae YLR038C COX12 Subunit VIb of cytochrome c oxidase which is the terminal member of the mitochondrial inner membrane electron transport chain required for assembly of fully active cytochrome c oxidase but not required for activity after assembly
similar to uniprot|Q04223 Saccharomyces cerevisiae YMR130W Hypothetical ORF
some similarities with uniprot|Q07980 Saccharomyces cerevisiae YLR035C MLH2 Protein required for DNA mismatch repair in mitosis and meiosis
similar to uniprot|P39685 Saccharomyces cerevisiae YMR129W POM152 Nuclear pore membrane glycoprotein may be involved in duplication of nuclear pores and nuclear pore complexes during S-phase
highly similar to uniprot|Q12078 Saccharomyces cerevisiae YLR034C SMF3 Putative metal transporter Nramp homolog homolog of SMF1 and SMF2
similar to uniprot|Q07979 Saccharomyces cerevisiae YLR033W RSC58 Remodels the structure of chromatin complex 58KDa subunit; Chromatin Remodeling Complex subunit
similar to uniprot|Q04217 Saccharomyces cerevisiae YMR128W ECM16 Essential DEAH-box ATP-dependent RNA helicase specific to the U3 snoRNP predominantly nucleolar in distribution required for 18S rRNA synthesis
similar to uniprot|P40963 Saccharomyces cerevisiae YMR127C SAS2 Histone acetyltransferase (HAT) catalytic subunit of the SAS complex (Sas2p-Sas4p-Sas5p) which acetylates free histones and nucleosomes and regulates transcriptional silencing member of the MYSTacetyltransferase family
similar to uniprot|P32849 Saccharomyces cerevisiae YLR032W RAD5 Single-stranded DNA-dependent ATPase involved in postreplication repair
similar to uniprot|Q04216 Saccharomyces cerevisiae YMR126C DLT1 Protein of unknown function deletion causes sensitivity to thermal stress
similar to uniprot|P34160 Saccharomyces cerevisiae YMR125W STO1 Large subunit of the nuclear mRNA cap-binding protein complex interacts with Npl3p to carry poly(A) mRNA from the nucleus to the cytoplasm also involved in mRNA degradation in the nucleus orthologous to mammalian CBP80
weakly similar to uniprot|P39523 Saccharomyces cerevisiae YMR124W Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cell periphery cytoplasm bud and bud neck
similar to uniprot|Q03880 Saccharomyces cerevisiae YMR123W PKR1 Protein of unknown function overproduction confers resistance to Pichia farinosa killer toxin
some similarities with uniprot|Q3E842 Saccharomyces cerevisiae YMR122W-A
highly similar to uniprot|P54780 Saccharomyces cerevisiae RPL15B and to uniprot|P05748 Saccharomyces cerevisiae YLR029C RPL15A
highly similar to uniprot|P38009 Saccharomyces cerevisiae YMR120C ADE17 Enzyme of 'de novo' purine biosynthesis containing both 5-aminoimidazole-4-carboxamide ribonucleotide transformylase and inosine monophosphate cyclohydrolase activities isozyme of Ade16p ade16 ade17 mutants require adenine and histidine
similar to uniprot|P54074 Saccharomyces cerevisiae YMR119W ASI1 Putative integral membrane E3 ubiquitin ligase genetic interactions suggest a role in negative regulation of amino acid uptake
highly similar to uniprot|P23542 Saccharomyces cerevisiae YLR027C AAT2 Cytosolic aspartate aminotransferase involved in nitrogen metabolism localizes to peroxisomes in oleate-grown cells
weakly similar to uniprot|Q04301 Saccharomyces cerevisiae YMR088C VBA1 Permease of basic amino acids in the vacuolar membrane
similar to uniprot|Q01590 Saccharomyces cerevisiae YLR026C SED5 Sed5p is a t-SNARE (soluble NSF attachment protein receptor) required in ER to Golgi transport
weakly similar to uniprot|P39929 Saccharomyces cerevisiae YLR025W SNF7 Involved in derepression of SUC2 in response to glucose limitation involved in glucose derepression
similar to uniprot|P32331 Saccharomyces cerevisiae YPR058W YMC1 Putative mitochondrial inner membrane transporter member of the mitochondrial carrier (MCF) family
similar to uniprot|P40544 Saccharomyces cerevisiae YIL023C
similar to uniprot|Q12354 Saccharomyces cerevisiae YLR118C
similar to uniprot|Q03921 Saccharomyces cerevisiae YDR141C DOP1
similar to uniprot|Q03920 Saccharomyces cerevisiae YDR140W MTQ2 Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family methylates release factor eRF1 (Sup45p) in vitro
similar to uniprot|Q03919 Saccharomyces cerevisiae YDR139C RUB1 Ubiquitin-like protein with similarity to mammalian NEDD8
similar to uniprot|Q12309 Saccharomyces cerevisiae YLR117C CLF1 essential splicesome assembly factor
some similarities with uniprot|Q12186 Saccharomyces cerevisiae YLR116W MSL5 Component of the commitment complex which defines the first step in the splicing pathway essential protein that interacts with Mud2p and Prp40p forming a bridge between the intron ends also involved in nuclear retention of pre-mRNA
highly similar to uniprot|P05756 Saccharomyces cerevisiae YDR064W RPS13 Protein component of the small (40S) ribosomal subunit; has similarity to E. coli S15 and rat S13 ribosomal proteins
similar to uniprot|Q12156 Saccharomyces cerevisiae YDR063W Hypothetical ORF
similar to uniprot|Q07824 Saccharomyces cerevisiae YLL028W TPO1 Proton-motive-force-dependent multidrug transporter of the major facilitator superfamily able to transport eight different compounds including polyamines quinidine cycloheximide and nystatin involved in excess spermidine detoxification
similar to uniprot|Q07825 Saccharomyces cerevisiae YLL029W Hypothetical ORF
some similarities with uniprot|Q07821 Saccharomyces cerevisiae YLL027W ISA1 Mitochondrial matrix protein involved in biogenesis of the iron-sulfur (Fe/S) cluster of Fe/S proteins isa1 deletion causes loss of mitochondrial DNA and respiratory deficiency depletion reduces growth on nonfermentable carbon sources
highly similar to uniprot|P31539 Saccharomyces cerevisiae YLL026W HSP104 Heat shock protein that cooperates with Ydj1p (Hsp40) and Ssa1p (Hsp70) to refold and reactivate previously denatured aggregated proteins responsive to stresses including: heat ethanol and sodium arsenite involved in [PSI ] propagation
some similarities with uniprot|P38741 Saccharomyces cerevisiae YHL024W RIM4 Putative RNA-binding protein required for the expression of early and middle sporulation genes
some similarities with uniprot|P38742 Saccharomyces cerevisiae YHL023C RMD11 Protein required for sporulation
uniprot|P49383 Kluyveromyces lactis KLLA0F18260g ADH2 Alcohol dehydrogenase 2
similar to uniprot|P05374 Saccharomyces cerevisiae YGR157W CHO2 First step in the methylation pathway for phosphatidylcholine biosynthesis Phosphatidyl-ethanolamine N-methyltransferase
similar to uniprot|P48240 Saccharomyces cerevisiae YGR158C MTR3 3'5' exoribonuclease exosome subunit nucleolar protein involved in export of mRNA and ribosomal subunits homologous to the E. coli exonuclease RNase PH
highly similar to uniprot|P15180 Saccharomyces cerevisiae YDR037W KRS1 Lysyl-tRNA synthetase also identified as a negative regulator of general control of amino acid biosynthesis
similar to uniprot|P38238 Saccharomyces cerevisiae YBR061C TRM7 2'-O-ribose methyltransferase methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop
mitochondrial 37S ribosomal protein RSM10
similar to uniprot|Q03201 Saccharomyces cerevisiae YDR041W RSM10 Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S10 ribosomal protein; essential for viability, unlike most other mitoribosomal proteins
similar to uniprot|P38239 Saccharomyces cerevisiae YBR062C Hypothetical ORF
weakly similar to uniprot|P38241 Saccharomyces cerevisiae YBR065C ECM2 Pre-mRNA splicing factor facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome function may be regulated by Slu7p
some similarities with uniprot|Q03125 Saccharomyces cerevisiae YDR043C NRG1 Transcriptional repressor that recruits the Cyc8p-Tup1p complex to promoters
uniprot|Q70W35 Kluyveromyces lactis putative coproporphyrinogen oxidase
highly similar to uniprot|Q04307 YDR045C Saccharomyces cerevisiae RPC11 RNA polymerase III subunit C11
similar to uniprot|P32833 YBR060C Saccharomyces cerevisiae ORC2 Subunit of the origin recognition complex
some similarities with uniprot|P38080 Saccharomyces cerevisiae YBR059C AKL1 Serine-threonine protein kinase member (with Ark1p and Prk1p) of the Ark kinase family
similar to uniprot|Q3E790 Saccharomyces cerevisiae YBR058C-A TSC3 Protein that stimulates the activity of serine palmitoyltransferase (Lcb1p,Lcb2p) several-fold; involved in sphingolipid biosynthesis
similar to uniprot|P28817 YDR036C Saccharomyces cerevisiae EHD3 Protein of unconfirmed function plays an indirect role in endocytic membrane trafficking member of a family of enoyl-CoA hydratase/isomerases
similar to uniprot|P38237 YBR058C Saccharomyces cerevisiae UBP14 Ubiquitin-specific protease that specifically disassembles unanchored ubiquitin chains
some similarities with uniprot|P38236 YBR057C Saccharomyces cerevisiae MUM2 Cytoplasmic protein essential for meiotic DNA replication and sporulation
highly similar to uniprot|P14843 YDR035W Saccharomyces cerevisiae ARO3 3-deoxy-D-arabino-heptulosonate-7- phosphate (DAHP) synthase
similar to uniprot|Q6Q5X2 Saccharomyces cerevisiae YDR034W-B Protein of unknown function; green fluorescent protein (GFP)-fusion protein
similar to uniprot|P38081 YBR056W Saccharomyces cerevisiae Hypothetical ORF
similar to uniprot|Q7LHX4 Saccharomyces cerevisiae YDR051C Hypothetical ORF
highly similar to uniprot|P00942 Saccharomyces cerevisiae YDR050C TPI1 induced under stress conditions triosephosphate isomerase
similar to uniprot|P38242 Saccharomyces cerevisiae YBR070C ALG14 Essential protein required for the second step of dolichyl-linked oligosaccharide synthesis; involved in N-linked glycosylation; similar to bacterial glycosyltransferases
similar to uniprot|P15992 Saccharomyces cerevisiae YBR072W HSP26 Small heat shock protein with chaperone activity that is regulated by a heat induced transition from an inactive oligomeric (24-mer) complex to an active dimer induced by heat upon entry into stationary phase and during sporulation
similar to uniprot|P32802 Saccharomyces cerevisiae YLR083C EMP70 Protein whose 24kDa cleavage product is found in endosome-enriched membrane fractions predicted to be a transmembrane protein
similar to uniprot|P46944 Saccharomyces cerevisiae YDR108W GSG1 Subunit of TRAPP (transport protein particle) a multi-subunit complex involved in targeting and/or fusion of ER-to-Golgi transport vesicles with their acceptor compartment protein has late meiotic role following DNA replication
similar to uniprot|Q12465 Saccharomyces cerevisiae YLR084C RAX2 N-glycosylated protein involved in the maintenance of bud site selection during bipolar budding localization requires Rax1p
some similarities with uniprot|Q74ZV5 Ashbya gossypii AGR094W AGR094Wp
similar to uniprot|Q04585 Saccharomyces cerevisiae YDR109C Hypothetical ORF
similar to uniprot|Q12509 Saccharomyces cerevisiae YLR085C ARP6 Nuclear actin-related protein involved in chromatin remodeling component of chromatin-remodeling enzyme complexes
similar to uniprot|Q12267 Saccharomyces cerevisiae YLR086W SMC4 subunit of the condensin complex which reorganizes chromosomes during cell division
similar to uniprot|Q12150 Saccharomyces cerevisiae YLR087C CSF1 Protein required for fermentation at low temperature
similar to uniprot|P39012 Saccharomyces cerevisiae YLR088W GAA1 Subunit of the GPI:protein transamidase complex removes the GPI-anchoring signal and attaches GPI (glycosylphosphatidylinositol) to proteins in the ER
some similarities with uniprot|O13329 Saccharomyces cerevisiae YDR110W FOB1 Nucleolar protein required for DNA replication fork blocking and recombinational hotspot activities binds to the replication fork barrier site in the rDNA region related to retroviral integrases
similar to uniprot|P52893 Saccharomyces cerevisiae YLR089C ALT1 putative alanine transaminase (glutamyc pyruvic transaminase)
similar to uniprot|P39102 Saccharomyces cerevisiae YLR090W XDJ1 Putative homolog of E. coli DnaJ closely related to Ydj1p
weakly similar to uniprot|P40316 Saccharomyces cerevisiae YDR113C PDS1 Securin that inhibits anaphase by binding separin Esp1p also blocks cyclin destruction and mitotic exit essential for cell cycle arrest in mitosis in the presence of DNA damage or aberrant mitotic spindles also present in meiotic nuclei
putative mitochondrial 54S ribosomal protein
similar to uniprot|Q04598 Saccharomyces cerevisiae YDR115W
mitochondrial 54S ribosomal protein MRPL1
similar to uniprot|Q04599 Saccharomyces cerevisiae YDR116C MRPL1 Mitochondrial ribosomal protein of the large subunit
similar to uniprot|Q04600 Saccharomyces cerevisiae YDR117C RBF64 Hypothetical ORF
similar to uniprot|P38359 Saccharomyces cerevisiae YBR294W SUL1 High affinity sulfate permease sulfate uptake is mediated by specific sulfate transporters Sul1p and Sul2p which control the concentration of endogenous activated sulfate intermediates and uniprot|Q12325 Saccharomyces cerevisiae YLR092W SUL2
highly similar to uniprot|Q02895 Saccharomyces cerevisiae YPL088W Putative aryl alcohol dehydrogenase transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance
some similarities with uniprot|Q2V2P9 Saccharomyces cerevisiae YDR119W-A Pi
similar to uniprot|P15565 Saccharomyces cerevisiae YDR120C TRM1 tRNA methyltransferase localizes to both the nucleus and mitochondrion to produce the modified base N2 N2-dimethylguanosine in tRNAs in both compartments
similar to uniprot|Q04603 Saccharomyces cerevisiae YDR121W DPB4 Shared subunit of DNA polymerase epsilon and of ISW2/yCHRAC chromatin accessibility complex involved in both chromosomal DNA replication and in inheritance of telomeric silencing
similar to uniprot|Q12255 Saccharomyces cerevisiae YLR093C NYV1 v-SNARE component of the vacuolar SNARE complex involved in vesicle fusion inhibits ATP-dependent Ca(2) transport activity of Pmc1p in the vacuolar membrane
similar to uniprot|Q750A2 Ashbya gossypii AGR055C AGR055Cp and some similarities with YHR176W uniprot|P38866 Saccharomyces cerevisiae YHR176W FMO1 Flavin-containing monooxygenase localized to the cytoplasmic face of the ER membrane catalyzes oxidation of biological thiols to maintain the ER redox buffer ratio for correct folding of disulfide-bonded proteins
some similarities with uniprot|Q7LGX3 Saccharomyces cerevisiae YLR094C GIS3 Protein of unknown function
similar to uniprot|Q12072 Saccharomyces cerevisiae YLR095C IOC2 Member of a complex (Isw1b) with Isw1p and Ioc4p
similar to uniprot|P13186 Saccharomyces cerevisiae YLR096W KIN2 Serine/threonine protein kinase involved in regulation of exocytosis localizes to the cytoplasmic face of the plasma membrane closely related to Kin1p and to YDR122W uniprot|P13185 Saccharomyces cerevisiae YDR122W KIN1 Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; closely related to Kin2p
weakly similar to uniprot|P26798 Saccharomyces cerevisiae YDR123C INO2 Component of the heteromeric Ino2p/Ino4p basic helix-loop-helix transcription activator that binds inositol/choline-responsive elements (ICREs) required for derepression of phospholipid biosynthetic genes in response to inositol depletion
similar to uniprot|Q12347 Saccharomyces cerevisiae YLR097C HRT3 Putative nuclear ubiquitin ligase based on computational analysis of large-scale protein-protein interaction data
similar to uniprot|P43634 Saccharomyces cerevisiae YLR098C CHA4 Zinc-finger protein with Zn[2]-Cys[6] fungal-type binuclear cluster domain DNA-binding transcriptional activator or CHA1 and some similarities to YOR337W uniprot|P47988 Saccharomyces cerevisiae YOR337W TEA1 Mutants are defective in Ty1 Enhancer-mediated Activation Ty1 enhancer activator
similar to uniprot|Q04623 Saccharomyces cerevisiae YDR125C ECM18 Protein of unknown function, similar to Rlp24p
some similarities with uniprot|Q3E798 Saccharomyces cerevisiae YLR099W-A Hypothetical ORF
similar to uniprot|Q04629 Saccharomyces cerevisiae YDR126W SWF1 Spore Wall Formation
highly similar to uniprot|P08566 Saccharomyces cerevisiae YDR127W ARO1 Pentafunctional arom protein catalyzes steps 2 through 6 in the biosynthesis of chorismate which is a precursor to aromatic amino acids
similar to uniprot|Q03897 Saccharomyces cerevisiae YDR128W Hypothetical ORF
highly similar to uniprot|Q12452 Saccharomyces cerevisiae YLR100W ERG27 3-keto sterol reductase catalyzes the last of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis mutants are sterol auxotrophs
highly similar to uniprot|P32599 Saccharomyces cerevisiae YDR129C SAC6 Fimbrin actin-bundling protein cooperates with Scp1p (calponin/transgelin) in the organization and maintenance of the actin cytoskeleton
similar to uniprot|Q08032 Saccharomyces cerevisiae YLR103C CDC45 DNA replication initiation factor
similar to uniprot|Q08045 Saccharomyces cerevisiae YLR104W Hypothetical ORF
similar to uniprot|P16658 Saccharomyces cerevisiae YLR105C
similar to uniprot|Q12019 Saccharomyces cerevisiae YLR106C MDN1 Huge dynein-related AAA-type ATPase (midasin) forms extended pre-60S particle with the Rix1 complex (Rix1p-Ipi1p-Ipi3p) may mediate ATP-dependent remodeling of 60S subunits and subsequent export from nucleoplasm to cytoplasm
similar to uniprot|Q12090 Saccharomyces cerevisiae YLR107W REX3 RNA exonuclease required for maturation of the RNA component of RNase MRP
some similarities with uniprot|Q03898 Saccharomyces cerevisiae YDR130C FIN1 Basic protein with putative coiled-coil regions that comprises a filament between spindle pole bodies
weakly similar to uniprot|Q03899 Saccharomyces cerevisiae YDR131C Hypothetical ORF
similar to uniprot|Q03900 Saccharomyces cerevisiae YDR132C Hypothetical ORF
similar to uniprot|P38013 Saccharomyces cerevisiae YLR109W AHP1 Thiol-specific peroxiredoxin reduces hydroperoxides to protect against oxidative damage function in vivo requires covalent conjugation to Urm1p
some similarities with uniprot|Q12127 Saccharomyces cerevisiae YLR110C CCW12 Cell wall protein
highly similar to uniprot|P32485 Saccharomyces cerevisiae YLR113W HOG1 Mitogen-activated protein kinase involved in osmoregulation
similar to uniprot|P39109 Saccharomyces cerevisiae YDR135C
similar to uniprot|Q06156 Saccharomyces cerevisiae YLR272C YCS4 Protein required for accurate sister chromatid segregation
highly similar to uniprot|P16622 Saccharomyces cerevisiae YOR176W HEM15 Ferrochelatase a mitochondrial inner membrane protein catalyzes the insertion of ferrous iron into protoporphyrin IX the eighth and final step in the heme biosynthetic pathway Yfh1p mediates the use of iron by Hem15p
similar to uniprot|Q03130 Saccharomyces cerevisiae YOR175C Hypothetical ORF
similar to uniprot|Q12343 Saccharomyces cerevisiae YOR174W MED4 Member of RNA Polymerase II transcriptional regulation mediator Stoichiometric member of mediator complex
weakly similar to uniprot|Q06152 Saccharomyces cerevisiae YLR271W Hypothetical ORF
highly similar to uniprot|Q6Q5L1 Saccharomyces cerevisiae YLR270W DCS1 Non-essential hydrolase involved in mRNA decapping may function in a feedback mechanism to regulate deadenylation contains pyrophosphatase activity and a HIT (histidine triad) motif interacts with neutral trehalase Nth1p
similar to uniprot|P22214 Saccharomyces cerevisiae YLR268W SEC22 R-SNARE protein assembles into SNARE complex with Bet1p Bos1p and Sed5p cycles between the ER and Golgi complex involved in anterograde and retrograde transport between the ER and Golgi synaptobrevin homolog
similar to uniprot|Q99321 Saccharomyces cerevisiae YOR163W DDP1 Diadenosine polyphosphate hydrolase member of the MutT family of nucleotide hydrolases with high specificity for diadenosine hexa- and pentaphosphates required for efficient hydrolysis of diphosphorylated inositol polyphosphates
similar to uniprot|Q12125 Saccharomyces cerevisiae YOR164C Hypothetical ORF
similar to uniprot|Q99287 Saccharomyces cerevisiae YOR165W SEY1 Synthetic Enhancement with YOP1
some similarities with uniprot|Q12104 Saccharomyces cerevisiae YOR166C Hypothetical ORF
highly similar to uniprot|P02380 Saccharomyces cerevisiae YOR167C RPS28A and highly similar to uniprot|P02380 Saccharomyces cerevisiae YLR264W RPS28B Protein component of the small (40S) ribosomal subunit
uniprot|Q9MEM7 Kluyveromyces lactis RED1 protein
highly similar to uniprot|P13188 Saccharomyces cerevisiae YOR168W GLN4 Glutamine tRNA synthetase monomeric class I tRNA synthetase that catalyzes the specific glutaminylation of tRNA(Glu) N-terminal domain proposed to be involved in enzyme-tRNA interactions
highly similar to uniprot|Q3E764 Saccharomyces cerevisiae YLR262C-A RBF7 Similar to C. elegans protein
highly similar to uniprot|Q99260 Saccharomyces cerevisiae YLR262C YPT6 Ras-like GTP binding protein involved in the secretory pathway, required for fusion of endosome-derived vesicles with the late Golgi; has similarity to the human GTPase, Rab6
similar to uniprot|Q12246 Saccharomyces cerevisiae YLR260W LCB5 Minor sphingoid long-chain base kinase paralog of Lcb4p responsible for few percent of the total activity possibly involved in synthesis of long-chain base phosphates which function as signaling molecules and similar to YOR171c
weakly similar to uniprot|P39927 Saccharomyces cerevisiae YGR156W PTI1 Pta1p Interacting protein
highly similar to uniprot|P17649 Saccharomyces cerevisiae YGR019W UGA1 Gamma-aminobutyrate (GABA) transaminase (4-aminobutyrate aminotransferase) involved in the 4-aminobutyrate and glutamate degradation pathways required for normal oxidative stress tolerance and nitrogen utilization
similar to uniprot|P40081 Saccharomyces cerevisiae YER134C Hypothetical ORF
some similarities with uniprot|Q12531 Saccharomyces cerevisiae YPR015c
similar to uniprot|Q12691 Saccharomyces cerevisiae YDR038C ENA5 Protein with similarity to P-type ATPase sodium pumps
weakly similar to uniprot|P39001 Saccharomyces cerevisiae YDR207C UME6 Regulator of both repression and induction of early meiotic genes. Ume6p requires Ume4 for mitotic repression and interacts with and requires Ime1p and Rim11p for induction of meiosis-specific transcription Ume6p is a C6 zinc finger URS1-binding protein.
uniprot|Q9C403 Kluyveromyces lactis Putative EBS1-like protein
similar to uniprot|P13099 Saccharomyces cerevisiae YLR234W TOP3 DNA Topoisomerase III
weakly similar to uniprot|Q03455 Saccharomyces cerevisiae YDR205W MSC2 Member of the cation diffusion facilitator family localizes to the endoplasmic reticulum and nucleus mutations affect the cellular distribution of zinc and also confer defects in meiotic recombination between homologous chromatids
similar to uniprot|P40165 Saccharomyces cerevisiae YNL200C
uniprot|Q7Z8J4 Kluyveromyces lactis KLLA0F20790g gcr2 protein
similar to uniprot|Q07657 Saccharomyces cerevisiae YDL225W SHS1 Component of the septin ring of the mother-bud neck that is required for cytokinesis septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane and they comprise the 10nm filaments seen with EM
some similarities with Saccharomyces cerevisiae YDL224C WHI4 and to uniprot|P34761 Saccharomyces cerevisiae YNL197C WHI3
some similarities with uniprot|Q07651 Saccharomyces cerevisiae YDL222C FMP45 The authentic non-tagged protein was localized to the mitochondria cell cortex protein not required for growth on nonfermentable carbon sources required for viability in stationary phase
weakly similar to uniprot|P32797 Saccharomyces cerevisiae YDL220C CDC13 Single stranded DNA-binding protein found at TG1-3 telomere G-tails regulates telomere replication through recruitment of specific sub-complexes but the essential function is telomere capping
similar to uniprot|P53870 Saccharomyces cerevisiae YNL193W Hypothetical ORF
similar to uniprot|P08004 Saccharomyces cerevisiae YNL192W CHS1 Chitin synthase I requires activation from zymogenic form in order to catalyze the transfer of N-acetylglucosamine (GlcNAc) to chitin required for repairing the chitin septum during cytokinesis transcription activated by mating factor
uniprot|P17819 Kluyveromyces lactis KLLA0F20988g GAP1 Glyceraldehyde-3-phosphate dehydrogenase 1
uniprot|P20369 Kluyveromyces lactis KLLA0F21010g ADH1 Alcohol dehydrogenase 1
mitochondrial 37S ribosomal protein MRPS9
similar to uniprot|P38120 Saccharomyces cerevisiae YBR146W MRPS9 Mitochondrial ribosomal protein of the small subunit
similar to uniprot|Q3E835 Saccharomyces cerevisiae YOL086W-A Hypothetical ORF identified by homology. See FEBS Letters [2000] 487:31-36.
weakly similar to uniprot|Q99247 Saccharomyces cerevisiae YOL087C Hypothetical ORF
highly similar to uniprot|P20434 Saccharomyces cerevisiae YBR154C RPB5 RNA polymerase subunit ABC27 common to RNA polymerases I II and III contacts DNA and affects transactivation
similar to uniprot|P33312 Saccharomyces cerevisiae YBR153W RIB7 Diaminohydroxyphoshoribosylaminopyrimidine deaminase catalyzes the second step of the riboflavin biosynthesis pathway
weakly similar to uniprot|P38282 Saccharomyces cerevisiae YBR152W SPP381 Suppressor of Pre-mRNA Processing mutant; U4/U6.U5-associated snRNP protein; contains a PEST proteolysis motif
similar to uniprot|P42945 Saccharomyces cerevisiae YJL109C UTP10 Nucleolar protein component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
similar to uniprot|P36125 Saccharomyces cerevisiae YKR030W GMH1 Golgi membrane protein of unknown function interacts with Gea1p and Gea2p required for localization of Gea2p computational analysis suggests a possible role in either cell wall synthesis or protein-vacuolar targeting
similar to uniprot|P36126 Saccharomyces cerevisiae YKR031C SPO14 Phospholipase D catalyzes the hydrolysis of phosphatidylcholine producing choline and phosphatidic acid involved in Sec14p-independent secretion required for meiosis and spore formation differently regulated in secretion and meiosis
some similarities with uniprot|P42944 Saccharomyces cerevisiae YJL110C GZF3 GATA zinc finger protein and Dal80p homolog that negatively regulates nitrogen catabolic gene expression by competing with Gat1p for GATA site binding function requires a repressive carbon source dimerizes with Dal80p and binds to Tor1p
similar to uniprot|P69771 Saccharomyces cerevisiae YKR035W-A DID2 Class E protein of the vacuolar protein-sorting (Vps) pathway associates reversibly with the late endosome has human ortholog that may be altered in breast tumors
highly similar to uniprot|P42943 Saccharomyces cerevisiae YJL111W CCT7 Subunit of the cytosolic chaperonin Cct ring complex
similar to uniprot|P47025 Saccharomyces cerevisiae YJL112W MDV1 WD repeat protein that regulates steps in the Dnm1p-dependent process of mitochondrial fission
similar to uniprot|P36131 Saccharomyces cerevisiae YKR037C SPC34 Component of Dam1p complex important for spindle and kinetochore integrity localized to nuclear side of spindle pole body and along mitotic spindle
highly similar to uniprot|P36132 Saccharomyces cerevisiae YKR038C KAE1 Putative glycoprotease that interacts with Bud32p which is a member of the novel protein kinase piD261 family
some similarities with uniprot|P08465 Saccharomyces cerevisiae YNL277W MET2 L-homoserine-O-acetyltransferase, catalyzes the conversion of homoserine to O-acetyl homoserine which is the first step of the methionine biosynthetic pathway
mitochondrial 37S ribosomal protein MRPS28
similar to uniprot|P21771 Saccharomyces cerevisiae YDR337W MRPS28 Mitochondrial ribosomal protein of the small subunit
some similarities with uniprot|P28007 Saccharomyces cerevisiae YHR089C GAR1 Protein component of the H/ACA snoRNP pseudouridylase complex involved in the modification and cleavage of the 18S pre-rRNA
similar to uniprot|Q05473 Saccharomyces cerevisiae YDR336W Hypothetical ORF
highly similar to uniprot|P52918 Saccharomyces cerevisiae YDR335W MSN5 Karyopherin involved in nuclear import and export shown to be responsible for nuclear import of replication protein A and for export of several proteins including Swi6p Far1p and Pho4p cargo dissociation involves binding to RanGTP
highly similar to uniprot|P38805 Saccharomyces cerevisiae YHR088W RPF1 Nucleolar protein involved in the assembly of the large ribosomal subunit contains a sigma(70)-like motif which is thought to bind RNA
uniprot|Q96WM8 Kluyveromyces lactis KLLA0F21692g Pdr5 Multidrug pump KlPDR5
similar to uniprot|P38804 Saccharomyces cerevisiae YHR087W Hypothetical ORF
similar to uniprot|Q05471 Saccharomyces cerevisiae YDR334W SWR1 Swi2/Snf2-related ATPase
similar to uniprot|P38767 Saccharomyces cerevisiae YHR032W Hypothetical ORF
similar to uniprot|P38779 Saccharomyces cerevisiae YHR052W CIC1 Core interacting component 1 ribosome biogenesis protein
similar to uniprot|P36053 Saccharomyces cerevisiae YKL160W ELF1 Protein of unknown function deletion inhibits Brome mosaic virus expression
similar to uniprot|P00427 Saccharomyces cerevisiae YHR051W COX6 Subunit VI of cytochrome c oxidase which is the terminal member of the mitochondrial inner membrane electron transport chain expression is regulated by oxygen levels
similar to uniprot|P47089 Saccharomyces cerevisiae YJR014W RBF22 Hypothetical ORF
similar to uniprot|P46951 Saccharomyces cerevisiae YGR198W Essential protein of unknown function
similar to uniprot|P42934 Saccharomyces cerevisiae YGR199W PMT6 Transfers mannose residues from dolichyl phosphate-D-mannose to specific serine/threonine residues of proteins in the secretory pathway dolichyl phosphate-D-mannose:protein O-D-mannosyltransferase
similar to uniprot|P42935 Saccharomyces cerevisiae YGR200C ELP2 Elongator protein part of the six-subunit RNA polymerase II Elongator histone acetyltransferase complex target of Kluyveromyces lactis zymocin
highly similar to uniprot|P39522 Saccharomyces cerevisiae YJR016C ILV3 Dihydroxyacid dehydratase catalyzes third step in the common pathway leading to biosynthesis of branched-chain amino acids
similar to uniprot|P38811 Saccharomyces cerevisiae YHR099W TRA1 Histone acetyltransferase component putative ortholog of human TRRAP which is an essential cofactor of c-Myc
weakly similar to uniprot|Q66RD4 Saccharomyces cerevisiae YDR349C YPS7 Putative GPI-anchored aspartic protease located in the cytoplasm and endoplasmic reticulum
similar to uniprot|P38810 Saccharomyces cerevisiae YHR098C SFB3 Member of the Sec24p family forms a complex with Sec23p that is involved in sorting of Pma1p into COPII vesicles peripheral ER membrane protein potential Cdc28p substrate
similar to uniprot|Q66RD5 Saccharomyces cerevisiae YDR348C Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and bud neck; potential Cdc28p substrate
mitochondrial 37S ribosomal protein MRP1
similar to uniprot|P10662 Saccharomyces cerevisiae YDR347W MRP1 Mitochondrial ribosomal protein of the small subunit MRP1 exhibits genetic interactions with PET122 encoding a COX3-specific translational activator and with PET123 encoding a small subunit mitochondrial ribosomal protein
similar to gnl|GLV|DEHA0F25982g Debaryomyces hansenii DEHA0F25982g
similar to uniprot|P31755 Saccharomyces cerevisiae YGL038C OCH1 Mannosyltransferase of the cis-Golgi apparatus initiates the polymannose outer chain elongation of N-linked oligosaccharides of glycoproteins
similar to uniprot|P53184 Saccharomyces cerevisiae YGL037C PNC1 NAD() salvage pathway gene pyrazinamidase and nicotinamidase
weakly similar to uniprot|P53185 Saccharomyces cerevisiae YGL036W Mtf1 Two Hybrid Clone 2
similar to uniprot|P32350 Saccharomyces cerevisiae YLL019C KNS1 Nonessential putative protein kinase of unknown cellular role member of the LAMMER family of protein kinases which are serine/threonine kinases also capable of phosphorylating tyrosine residues
some similarities with uniprot|Q6Q5F4 Saccharomyces cerevisiae YPR015C Hypothetical ORF
some similarities with uniprot|Q02199 Saccharomyces cerevisiae YGL172W NUP49 Subunit of the Nsp1p-Nup57p-Nup49p-Nic96p subcomplex of the nuclear pore complex (NPC) required for nuclear export of ribosomes
similar to uniprot|P22147 Saccharomyces cerevisiae YGL173C KEM1 5'-3' exonuclease involved in mRNA decay evolutionarily conserved component of cytoplasmic processing (P) bodies plays a role in microtubule-mediated processes filamentous growth and ribosomal RNA maturation
weakly similar to uniprot|P46947 Saccharomyces cerevisiae YGL174W BUD13 Protein involved in bud-site selection diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern
weakly similar to uniprot|P46946 Saccharomyces cerevisiae YGL175C SAE2 Protein with a role in accurate meiotic and mitotic double-strand break repair phosphorylated in response to DNA damage and required for normal resistance to DNA-damaging agents
similar to uniprot|P33895 Saccharomyces cerevisiae YOL069W NUF2 Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p) involved in chromosome segregation spindle checkpoint activity and kinetochore clustering
similar to uniprot|Q07350 Saccharomyces cerevisiae YDL043C PRP11 Subunit of the SF3a splicing factor complex required for spliceosome assembly
mitochondrial 37S ribosomal protein MRPS35
similar to uniprot|P53292 Saccharomyces cerevisiae YGR165W MRPS35 Mitochondrial ribosomal protein of the small subunit
some similarities with uniprot|P47069 Saccharomyces cerevisiae YJL019W MPS3 Essential integral membrane protein required for spindle pole body duplication and for nuclear fusion localizes to the spindle pole body half bridge interacts with DnaJ-like chaperone Jem1p and with centrin homolog Cdc31p
weakly similar to uniprot|P47071 Saccharomyces cerevisiae YJL016W
highly similar to uniprot|P39077 Saccharomyces cerevisiae YJL014W CCT3 Subunit of the cytosolic chaperonin Cct ring complex related to Tcp1p required for the assembly of actin and tubulins in vivo
similar to uniprot|P41695 Saccharomyces cerevisiae YGR188C BUB1 Protein kinase that forms a complex with Mad1p and Bub3p that is crucial in the checkpoint mechanism required to prevent cell cycle progression into anaphase in the presence of spindle damage associates with centromere DNA via Skp1p
highly similar to uniprot|P47075 Saccharomyces cerevisiae YJL012C VTC4 Phosphate metabolism transcription is regulated by PHO system polyphosphate synthetase (putative)
similar to uniprot|P47076 Saccharomyces cerevisiae YJL011C RPC17 RNA polymerase III subunit C17 physically interacts with C31 C11 and TFIIIB70 may be involved in the recruitment of pol III by the preinitiation complex
similar to uniprot|P53301 Saccharomyces cerevisiae YGR189C CRH1 Putative glycosidase of the cell wall may have a role in cell wall architecture
some similarities with uniprot|Q04814 Saccharomyces cerevisiae YMR252C Hypothetical ORF
highly similar to uniprot|P35181 Saccharomyces cerevisiae YLR170C APS1 Small subunit of the clathrin-associated adaptor complex AP-1 which is involved in protein sorting at the trans-Golgi network homolog of the sigma subunit of the mammalian clathrin AP-1 complex
highly similar to uniprot|P32469 Saccharomyces cerevisiae YLR172C DPH5 Methyltransferase required for synthesis of diphthamide which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p) not essential for viability GFP-Dph5p fusion protein localizes to the cytoplasm
weakly similar to uniprot|Q06247 Saccharomyces cerevisiae YLR173W Hypothetical ORF
some similarities with uniprot|P12351 Saccharomyces cerevisiae YLR256W HAP1
similar to uniprot|Q06563 Saccharomyces cerevisiae YLR251W SYM1 Protein homologous to mammalian peroxisomal membrane protein Mpv17 required for ethanol metabolismand induced by heat shock localized to the inner mitochondrial membrane
similar to uniprot|Q06567 Saccharomyces cerevisiae YLR253W Hypothetical ORF
similar to uniprot|P53110 Saccharomyces cerevisiae YGL159W Hypothetical ORF
uniprot|Q6DR96 Kluyveromyces lactis HAP1
weakly similar to uniprot|P53109 Saccharomyces cerevisiae YGL160W Hypothetical ORF
similar to uniprot|Q06146 Saccharomyces cerevisiae YLR257W Hypothetical ORF
some similarities with uniprot|P43597 Saccharomyces cerevisiae YFR016C Hypothetical ORF
highly similar to uniprot|P23337 Saccharomyces cerevisiae or YLR258W uniprot|P27472 Saccharomyces cerevisiae
similar to uniprot|P22517 Saccharomyces cerevisiae YOL016C CMK2 Calmodulin-dependent protein kinase and uniprot|P27466 Saccharomyces cerevisiae YFR014C CMK1
some similarities with uniprot|P43596 Saccharomyces cerevisiae YFR013W IOC3 Member of a complex (Isw1a) with Isw1p that has nucleosome-stimulated ATPase activity and represses transcription initiation by specific positioning of a promoter proximal dinucleosome has homology to Esc8p which is involved in silencing
some similarities with uniprot|O13581 Saccharomyces cerevisiae YDL128W VCX1 Vacuolar H+/Ca2+ exchanger, has similarity to sodium/calcium exchangers, including the bovine Na+/Ca2+,K+ antiporter
highly similar to uniprot|P10964 Saccharomyces cerevisiae YOR341W RPA190 RNA polymerase I subunit largest subunit of RNA polymerase I
similar to uniprot|P39730 Saccharomyces cerevisiae YAL035W FUN12 GTPase required for general translation initiation by promoting Met-tRNAiMet binding to ribosomes and ribosomal subunit joining homolog of bacterial IF2
highly similar to uniprot|P39729 Saccharomyces cerevisiae YAL036C RBG1 GTPase that interacts with ribosomes member of the DRG family of GTP-binding proteins
similar to uniprot|Q12182 Saccharomyces cerevisiae YOR342C Hypothetical ORF
uniprot|Q92242 Kluyveromyces lactis SCK1 Multicopy supressor of caseine kinase 1 mutation and weakly similar to uniprot|P33122 Saccharomyces cerevisiae YOR344C TYE7 may be involved in glycolytic gene expression TYE7 a 33 kDa serine-rich protein is a potential member of the basic region/helix-loop-helix/leucine-zipper protein family
similar to uniprot|P12689 Saccharomyces cerevisiae YOR346W REV1 Deoxycytidyl transferase forms a complex with the subunits of DNA polymerase zeta Rev3p and Rev7p involved in repair of abasic sites in damaged DNA
uniprot|Q875M9 Kluyveromyces lactis KLLA0F23397g PYK1 Pyruvate kinase
similar to uniprot|P15380 Saccharomyces cerevisiae YOR348C PUT4 proline-specific permease (also capable of transporting alanine and glycine) putative proline-specific permease
weakly similar to uniprot|P40987 Saccharomyces cerevisiae YOR349W CIN1 Tubulin folding factor D involved in beta-tubulin (Tub2p) folding isolated as mutant with increased chromosome loss and sensitivity to benomyl
similar to uniprot|P24719 Saccharomyces cerevisiae YOR351C MEK1 Meiosis-specific serine/threonine protein kinase functions in meiotic checkpoint
highly similar to uniprot|P06208 Saccharomyces cerevisiae YNL104C LEU4 Alpha-isopropylmalate synthase (2-isopropylmalate synthase) the main isozyme responsible for the first step in the leucine biosynthesis pathway
similar to uniprot|Q12271 YOR109w Saccharomyces cerevisiae INP53 Phosphatidylinositol 4,5-bisphosphate 5-phosphatase
similar to uniprot|P53930 Saccharomyces cerevisiae YNL107W YAF9 Subunit of both the NuA4 histone H4 acetyltransferase complex and the SWR1 complex may function to antagonize silencing near telomeres interacts directly with Swc4p has homology to human leukemogenic protein AF9 contains a YEATS domain
similar to uniprot|Q6B220 Saccharomyces cerevisiae YOR110W
similar to uniprot|Q99210 Saccharomyces cerevisiae YOR111W Hypothetical ORF
similar to uniprot|P53927 Saccharomyces cerevisiae YNL110C NOP15 Constituent of 66S pre-ribosomal particles involved in 60S ribosomal subunit biogenesis localizes to both nucleolus and cytoplasm
similar to uniprot|P40312 Saccharomyces cerevisiae YNL111C CYB5 Cytochrome b5 involved in the sterol and lipid biosynthesis pathways required for sterol C5-6 and fatty acid desaturation
similar to uniprot|Q12453 Saccharomyces cerevisiae YOR112W Hypothetical ORF
similar to uniprot|P24783 Saccharomyces cerevisiae YNL112W DBP2 Essential ATP-dependent RNA helicase of the DEAD-box protein family involved in nonsense-mediated mRNA decay and rRNA processing
similar to uniprot|P28000 Saccharomyces cerevisiae YNL113W RPC19 RNA polymerase subunit common to RNA polymerases I and III
weakly similar to uniprot|P41696 Saccharomyces cerevisiae YOR113W AZF1 Zinc-finger transcription factor involved in induction of CLN3 transcription in response to glucose genetic and physical interactions indicate a possible role in mitochondrial transcription or genome maintenance
similar to uniprot|Q12219 Saccharomyces cerevisiae YOR114W Hypothetical ORF
similar to uniprot|Q99394 Saccharomyces cerevisiae YOR115C TRS33 Component of the targeting complex (TRAPP) involved in ER to Golgi membrane traffic
similar to uniprot|P38822 Saccharomyces cerevisiae YHR114W BZZ1 SH3 domain protein implicated in the regulation of actin polymerization able to recruit actin polymerization machinery through its SH3 domains colocalizes with cortical actin patches and Las17p interacts with type I myosins
similar to uniprot|P53925 Saccharomyces cerevisiae YNL115C Hypothetical ORF
some similarities with uniprot|P53924 Saccharomyces cerevisiae YNL116W DMA2 Protein involved in regulating spindle position and orientation functionally redundant with Dma1p homolog of S. pombe Dma1 and H. sapiens Chfr
highly similar to uniprot|P30952 Saccharomyces cerevisiae YNL117W MLS1 Malate synthase enzyme of the glyoxylate cycle involved in utilization of non-fermentable carbon sources expression is subject to carbon catabolite repression localizes in peroxisomes during growth in oleic acid medium
similar to uniprot|P53550 Saccharomyces cerevisiae YNL118C DCP2 Protein required for the decapping of mRNAs functions to allow the production of active Dcp1p contains a pyrophosphatase MutT motif and several alpha-helical leucine-rich motifs
similar to uniprot|P53923 Saccharomyces cerevisiae YNL119W NCS2 Protein with a role in urmylation and in invasive and pseudohyphal growth inhibits replication of Brome mosaic virus in S. cerevisiae which is a model system for studying replication of positive-strand RNA viruses in their natural hosts
similar to uniprot|P38824 Saccharomyces cerevisiae YHR116W COX23 Mitochondrial intermembrane space protein that functions in mitochondrial copper homeostasis essential for functional cytochrome oxidase expression homologous to Cox17p
similar to uniprot|P07213 Saccharomyces cerevisiae YNL121C TOM70 Translocase of Outer Mitochondrial membrane 70 kDa mitochondrial specialized import receptor of the outer membrane
similar to uniprot|P53921 Saccharomyces cerevisiae YNL122C Hypothetical ORF
similar to uniprot|P53920 Saccharomyces cerevisiae YNL123W shows protein sequence similarity to the mammalian Omi/HtrA2 family of serine proteases
similar to uniprot|P38826 Saccharomyces cerevisiae YHR118C ORC6 Subunit of the origin recognition complex which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing may be phosphorylated by Cdc28p
similar to uniprot|P38827 Saccharomyces cerevisiae YHR119W SET1 Histone methyltransferase subunit of the COMPASS complex which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres contains a SET domain
similar to uniprot|P25846 Saccharomyces cerevisiae YHR120W MSH1 DNA-binding protein of the mitochondria involved in repair of mitochondrial DNA has ATPase activity and binds to DNA mismatches has homology to E. coli MutS transcription is induced during meiosis
some similarities with uniprot|P53919 Saccharomyces cerevisiae YNL124W NAF1 Protein required for the assembly of box H/ACA snoRNPs and for pre-rRNA processing, forms a complex with Shq1p and interacts with H/ACA snoRNP components Nhp2p and Cbf5p
similar to uniprot|P53918 Saccharomyces cerevisiae YNL125C ESBP6 Protein with similarity to monocarboxylate permeases appears not to be involved in transport of monocarboxylates such as lactate pyruvate or acetate across the plasma membrane
similar to uniprot|P53540 YNL126W Saccharomyces cerevisiae SPC98 Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex
similar to uniprot|P53917 Saccharomyces cerevisiae YNL127W FAR11 Protein involved in G1 cell cycle arrest in response to pheromone in a pathway different from the Far1p-dependent pathway interacts with Far3p Far7p Far8p Far9p and Far10p
similar to uniprot|P38828 Saccharomyces cerevisiae YHR121W LSM12 Protein containing an Lsm domain and an AD domain may bind RNA and have a role in RNA processing
similar to uniprot|P53916 Saccharomyces cerevisiae YNL128W
similar to uniprot|P53915 Saccharomyces cerevisiae YNL129W NRK1 Nicotinamide riboside kinase catalyzes the synthesis of nicotinamide nucleotide (NMN) from nicotinamide riboside involved in a salvage pathway for NAD biosynthesis
similar to uniprot|P38829 Saccharomyces cerevisiae YHR122W Protein required for cell viability
similar to uniprot|P17898 Saccharomyces cerevisiae YNL130C CPT1 and similar to uniprot|P22140 Saccharomyces cerevisiae YHR123w EPT1 Cholinephosphotransferase
similar to uniprot|P49334 Saccharomyces cerevisiae YNL131W TOM22 Translocase of Outer Mitochondrial membrane Mitochondrial import receptor complex protein
highly similar to uniprot|P53914 Saccharomyces cerevisiae YNL132W KRE33 Essential protein of unknown function heterozygous mutant shows haploinsufficiency in K1 killer toxin resistance
some similarities with uniprot|P38830 Saccharomyces cerevisiae YHR124W NDT80 Meiosis-specific transcription factor required for exit from pachytene and for full meiotic recombination activates middle sporulation genes competes with Sum1p for binding to promoters containing middle sporulation elements (MSE)
weakly similar to uniprot|P53913 Saccharomyces cerevisiae YNL133C FYV6 Protein of unknown function required for survival upon exposure to K1 killer toxin proposed to regulate double-strand break repair via non-homologous end-joining
similar to uniprot|P53912 Saccharomyces cerevisiae YNL134C similarity to dehydrogenases
some similarities with uniprot|P47179 Saccharomyces cerevisiae YJR151C DAN4 Cell wall mannoprotein with similarity to Tir1p, Tir2p, Tir3p, and Tir4p
some similarities with uniprot|P13902 Saccharomyces cerevisiae YOL108C INO4 Transcription factor required for derepression of inositol-choline-regulated genes involved in phospholipid synthesis; forms a complex, with Ino2p, that binds the inositol-choline-responsive element through a basic helix-loop-helix domain
similar to uniprot|P38071 Saccharomyces cerevisiae YBR026C ETR1 2-enoyl thioester reductase member of the medium chain dehydrogenase/reductase family localized to in mitochondria where it has a probable role in fatty acid synthesis
similar to uniprot|P38069 Saccharomyces cerevisiae YBR015C MNN2 Alpha-1 2-mannosyltransferase responsible for addition of the first alpha-1 2-linked mannose to form the branches on the mannan backbone of oligosaccharides localizes to an early Golgi compartment
similar to uniprot|P38070 Saccharomyces cerevisiae YBR028C Hypothetical ORF
similar to uniprot|P38221 Saccharomyces cerevisiae YBR029C CDS1 Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase) an enzyme that catalyzes that conversion of CTP phosphate into diphosphate CDP-diaclglyerol a critical step in the synthesis of all major yeast phospholipids
similar to uniprot|P19736 Saccharomyces cerevisiae YDL030W PRP9 Subunit of the SF3a splicing factor complex required for spliceosome assembly
similar to uniprot|Q12389 Saccharomyces cerevisiae YDL031W DBP10 Essential protein involved in ribosome biogenesis
similar to uniprot|Q12093 Saccharomyces cerevisiae YDL033C SLM3 Mitochondrial protein with a potential role in protein synthesis the bacterial homolog is responsible for the 2-thiolation of mnm5s2U34 in tRNALys tRNAGlu and tRNAGln
similar to uniprot|P32179 Saccharomyces cerevisiae YOL064C MET22 Bisphosphate-3'-nucleotidase involved in salt tolerance and methionine biogenesis dephosphorylates 3'-phosphoadenosine-5'-phosphate and 3'-phosphoadenosine-5'-phosphosulfate intermediates of the sulfate assimilation pathway
similar to uniprot|Q757V1 Ashbya gossypii AEL089C AEL089Cp and some similarites with YDL035C uniprot|Q12361 Saccharomyces cerevisiae YDL035C GPR1 Plasma membrane G-protein coupled receptor that interacts with the heterotrimeric G protein alpha subunit Gpa2p and with Plc1p sensor that integrates nutritional signals with the modulation of cell fate via PKA and cAMP synthesis
similar to uniprot|Q08227 Saccharomyces cerevisiae YOL065C INP54 Phosphatidylinositol 4 5-bisphosphate 5-phosphatase with a role in secretion localizes to the endoplasmic reticulum via the C-terminal tail lacks the Sac1 domain and proline-rich region found in the other 3 INP proteins
similar to uniprot|Q12362 Saccharomyces cerevisiae and weakly similar to YDL036C uniprot|Q12069 Saccharomyces cerevisiae YDL036C Hypothetical ORF
similar to uniprot|Q02555 Saccharomyces cerevisiae YMR239C RNT1 RNAase III cleaves a stem-loop structure at the 3' end of U2 snRNA to ensure formation of the correct U2 3' end
similar to uniprot|Q08773 Saccharomyces cerevisiae YOR304W ISW2 Member of the imitation-switch (ISWI) class of ATP-dependent chromatin remodeling complexes ATPase component that with Itc1p forms a complex required for repression of a-specific genes INO1 and early meiotic genes during mitotic growth
similar to uniprot|P07258 Saccharomyces cerevisiae YOR303W CPA1 Small subunit of carbamoyl phosphate synthetase, which catalyzes a step in the synthesis of citrulline, an arginine precursor; translationally regulated by an attenuator peptide encoded by YOR302W within the CPA1 mRNA 5'-leader, member of GLC.2530
similar to uniprot|Q08760 Saccharomyces cerevisiae YOR301W RAX1 Protein involved in bud site selection during bipolar budding localization requires Rax2p
similar to uniprot|Q05031 Saccharomyces cerevisiae YMR238W DFG5 Mannosidase essential glycosylphosphatidylinositol (GPI)-anchored membrane protein required for cell wall biogenesis involved in filamentous growth homologous to Dcw1p
similar to uniprot|Q88DE0 Pseudomonas putida PP4887 PP_4887 Hypothetical protein
similar to uniprot|Q08754 Saccharomyces cerevisiae YOR299W BUD7 Protein involved in bud-site selection diploid mutants display an axial-like budding pattern
highly similar to uniprot|Q05027 Saccharomyces cerevisiae YMR236W TAF9
some similarities with uniprot|Q86ZS7 Saccharomyces cerevisiae YOR298C-A MBF1 Transcriptional coactivator that bridges the DNA-binding region of Gcn4p and TATA-binding protein Spt15p; suppressor of frameshift mutations
similar to uniprot|P11745 Saccharomyces cerevisiae YMR235C RNA1 GTPase activating protein (GAP) for Gsp1p involved in nuclear transport
weakly similar to uniprot|Q08750 Saccharomyces cerevisiae YOR298W MUM3 Protein of unknown function involved in the organization of the outer spore wall layers; has similarity to the tafazzins superfamily of acetyltransferases
some similarities with uniprot|Q08749 Saccharomyces cerevisiae YOR297C TIM18 mitochondrial inner membrane translocase
similar to uniprot|P06842 Saccharomyces cerevisiae YFL026W STE2 Receptor for alpha-factor pheromone seven transmembrane-domain protein that interacts with both pheromone and a heterotrimeric G protein to initiate the signaling response that leads to mating between haploid a and alpha cells
similar to uniprot|P43571 Saccharomyces cerevisiae YFL025C BST1 GPI inositol deacylase of the ER that negatively regulates COPII vesicle formation prevents production of vesicles with defective subunits required for proper discrimination between resident ER proteins and Golgi-bound cargo molecules
similar to uniprot|P43572 Saccharomyces cerevisiae YFL024C EPL1 Component of NuA4 which is an essential histone H4/H2A acetyltransferase complex homologous to Drosophila Enhancer of Polycomb
similar to uniprot|P43573 Saccharomyces cerevisiae YFL023W BUD27 Protein involved in bud-site selection nutrient signaling and gene expression controlled by the TOR kinase diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
some similarities with uniprot|Q12202 Saccharomyces cerevisiae YLR054C OSW2 Protein of unknown function proposed to be involved in the assembly of the spore wall
highly similar to uniprot|P15625 Saccharomyces cerevisiae YFL022C
weakly similar to uniprot|Q12345 Saccharomyces cerevisiae YLR052W IES3 Subunit of the INO80 chromatin remodeling complex
similar to uniprot|Q12035 Saccharomyces cerevisiae YLR051C Protein required for cell viability
some similarities with uniprot|P43574 Saccharomyces cerevisiae YFL021W GAT1 Transcriptional activator of genes involved in nitrogen catabolite repression member of the GATA family of DNA binding proteins activity and localization regulated by nitrogen limitation and Ure2p
similar to uniprot|Q03690 Saccharomyces cerevisiae YMR012W
similar to uniprot|P36095 Saccharomyces cerevisiae YKL041W VPS24 involved in secretion
some similarities with uniprot|P21957 Saccharomyces cerevisiae YHL020C OPI1 Transcriptional regulator of a variety of genes phosphorylation by protein kinase A stimulates Opi1p function in negative regulation of phospholipid biosynthetic genes
some similarities with uniprot|P38700 Saccharomyces cerevisiae YHL019C APM2 homologous to the medium chain of mammalian clathrin-associated protein complex Similar to clathrin coat proteins
similar to uniprot|P38744 Saccharomyces cerevisiae YHL018W Hypothetical ORF
similar to uniprot|P32860 Saccharomyces cerevisiae YKL040C
similar to uniprot|P32857 Saccharomyces cerevisiae YKL039W PTM1 Putative membrane protein
similar to uniprot|P38701 Saccharomyces cerevisiae YHL015W RPS20
similar to uniprot|P38746 Saccharomyces cerevisiae YHL014C YLF2 Protein of unknown function, has weak similarity to E. coli GTP-binding protein gtp1
similar to uniprot|P38747 Saccharomyces cerevisiae YHL013C Hypothetical ORF
some similarities with uniprot|P32862 Saccharomyces cerevisiae YKL038W RGT1 Glucose-responsive transcription factor that regulates expression of several glucose transporter (HXT) genes in response to glucose binds to promoters and acts both as a transcriptional activator and repressor
highly similar to uniprot|P32861 Saccharomyces cerevisiae YKL035W UGP1 UDP-glucose pyrophosphorylase or UTP-glucose-1-phosphate uridylyltransferase EC:2.7.7.9
similar to uniprot|P36096 Saccharomyces cerevisiae YKL034W TUL1 Transmembrane Ubiquitin Ligase
highly similar to uniprot|P38689 Saccharomyces cerevisiae YHL011C PRS3 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase involved in nucleotide histidine and tryptophan biosynthesis one of a five related enzymes which are active as heteromultimeric complexes
similar to uniprot|P38748 YHL010C Saccharomyces cerevisiae Hypothetical ORF
weakly similar to uniprot|P36097 Saccharomyces cerevisiae YKL033W Protein of unknown function localized to the cytoplasm.
similar to uniprot|P38750 Saccharomyces cerevisiae YHL008C Hypothetical ORF
similar to uniprot|Q04264 Saccharomyces cerevisiae YMR076C PDS5 Protein required for establishment and maintenance of sister chromatid condensation and cohesion colocalizes with cohesin on chromosomes in an interdependent manner may function as a protein-protein interaction scaffold
similar to uniprot|Q04779 Saccharomyces cerevisiae YMR075W RCO1 Nuclear protein of unknown function
weakly similar to uniprot|Q04773 Saccharomyces cerevisiae YMR074C Hypothetical ORF
similar to uniprot|P87108 Saccharomyces cerevisiae YHR005C-A MRS11 Essential protein of the mitochondrial intermembrane space forms a complex with Tim9p (TIM10 complex) that mediates insertion of hydrophobic proteins at the inner membrane has homology to Mrs5p which is also involved in this process
similar to uniprot|Q00873 Saccharomyces cerevisiae YKL087C CYT2 Cytochrome c1 heme lyase involved in maturation of cytochrome c1 which is a subunit of the mitochondrial ubiquinol-cytochrome-c reductase links heme covalently to apocytochrome c1
uniprot|Q9Y7B7 Kluyveromyces lactis KLLA0F25916g GPA1 Guanine nucleotide-binding protein alpha-1 subunit
similar to uniprot|P36077 Saccharomyces cerevisiae YKL086W SRX1 Sulfiredoxin contributes to oxidative stress resistance by reducing cysteine-sulfinic acid groups in the peroxiredoxins Tsa1p and Ahp1p that are formed upon exposure to oxidants conserved in higher eukaryotes
highly similar to uniprot|P17505 Saccharomyces cerevisiae YKL085W MDH1 Mitochondrial malate dehydrogenase catalyzes interconversion of malate and oxaloacetate involved in the tricarboxylic acid (TCA) cycle
similar to uniprot|P36078 Saccharomyces cerevisiae YKL084W HOT13 Mitochondrial intermembrane space protein first component of a pathway mediating assembly of small TIM (Translocase of the Inner Membrane) complexes which escort hydrophobic inner membrane proteins en route to the TIM22 complex
some similarities with uniprot|Q04749 Saccharomyces cerevisiae YMR068W AVO2 Component of a complex containing the Tor2p kinase and other proteins
some similarities with uniprot|P54730 Saccharomyces cerevisiae YMR067C UBX4 UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p
weakly similar to uniprot|Q04748 Saccharomyces cerevisiae YMR066W SOV1 Synthesis Of Var (putative) involved in respiration
similar to uniprot|P36080 Saccharomyces cerevisiae YKL082C RRP14 Required for normal pre-rRNA Processing Protein required for cell viability
elongation factor 1 gamma domain-containing protein
similar to uniprot|P36008 Saccharomyces cerevisiae YKL081W TEF4 Translation elongation factor EF-1gamma
highly similar to uniprot|P31412 Saccharomyces cerevisiae YKL080W VMA5 Vacuolar H ATPase subunit C of the catalytic (V1) sector
similar to uniprot|Q12358 Saccharomyces cerevisiae YLL057C JLP1 to Fe(II)-dependent sulfonate/alpha-ketoglutarate dioxygenase
similar to uniprot|Q04746 Saccharomyces cerevisiae YMR065W KAR5 Protein required for nuclear membrane fusion during karyogamy localizes to the membrane with a soluble portion in the endoplasmic reticulum lumen may form a complex with Jem1p and Kar2p expression of the gene is regulated by pheromone
weakly similar to uniprot|P32493 Saccharomyces cerevisiae YMR064W AEP1 Protein required for expression of the mitochondrial OLI1 gene encoding subunit 9 of F1-F0 ATP synthase
similar to uniprot|P36009 Saccharomyces cerevisiae YKL078W DHR2 Predominantly nucleolar DEAH-box RNA helicase required for 18S rRNA synthesis
highly similar to uniprot|P39932 Saccharomyces cerevisiae YDR536W STL1 Glycerol proton symporter of the plasma membrane subject to glucose-induced inactivation strongly but transiently induced when cells are subjected to osmotic shock
highly similar to uniprot|Q04728 Saccharomyces cerevisiae YMR062C ECM40 Mitochondrial ornithine acetyltransferase catalyzes the fifth step in arginine biosynthesis also possesses acetylglutamate synthase activity regenerates acetylglutamate while forming ornithine
similar to uniprot|P25298 Saccharomyces cerevisiae YMR061W RNA14 Cleavage and polyadenylation factor I (CF I) component involved in cleavage and polyadenylation of mRNA 3' ends bridges interaction between Rna15p and Hrp1p in the CF I complex
similar to uniprot|P50110 Saccharomyces cerevisiae YMR060C SAM37 Component of the mitochondrial outer membrane sorting and assembly machinery (SAM) complex required for the sorting of some proteins to the outer membrane after import by the TOM complex
weakly similar to uniprot|Q04675 Saccharomyces cerevisiae YMR059W SEN15 Subunit of the tRNA splicing endonuclease which is composed of Sen2p Sen15p Sen34p and Sen54p
similar to uniprot|P36081 Saccharomyces cerevisiae YKL077W
similar to uniprot|P36083 Saccharomyces cerevisiae YKL075C Hypothetical ORF
similar to uniprot|P38993 Saccharomyces cerevisiae YMR058W FET3 Ferro-O2-oxidoreductase required for high-affinity iron uptake and involved in mediating resistance to copper ion toxicity belongs to class of integral membrane multicopper oxidases
similar to uniprot|P26448 Saccharomyces cerevisiae YMR055C BUB2 Mitotic exit network regulator forms GTPase-activating Bfa1p-Bub2p complex that binds Tem1p and spindle pole bodies blocks cell cycle progression before anaphase in response to spindle and kinetochore damage
weakly similar to uniprot|P36084 Saccharomyces cerevisiae YKL074C
similar to uniprot|P36016 Saccharomyces cerevisiae YKL073W LHS1 Molecular chaperone of the endoplasmic reticulum lumen involved in polypeptide translocation and folding member of the Hsp70 family localizes to the lumen of the ER regulated by the unfolded protein response pathway
similar to uniprot|P37296 Saccharomyces cerevisiae YMR054W STV1 Subunit of vacuolar-ATPase V0 domain one of two isoforms (Stv1p and Vph1p) Stv1p is located in V-ATPase complexes of the Golgi and endosomes while Vph1p is located in V-ATPase complexes of the vacuole
similar to uniprot|P36085 Saccharomyces cerevisiae YKL072W STB6 and similar to uniprot|P46679 Saccharomyces cerevisiae YMR053c STB2
similar to uniprot|P46671 Saccharomyces cerevisiae YMR052W FAR3 Protein involved in G1 cell cycle arrest in response to pheromone in a pathway different from the Far1p-dependent pathway interacts with Far7p Far8p Far9p Far10p and Far11p
highly similar to uniprot|P36088 Saccharomyces cerevisiae YKL069W Hypothetical ORF
similar to uniprot|Q04660 Saccharomyces cerevisiae YMR049C ERB1 Protein required for maturation of the 25S and 5.8S ribosomal RNAs homologous to mammalian Bop1
some similarities with uniprot|Q04659 Saccharomyces cerevisiae YMR048W CSM3 Protein required for accurate chromosome segregation during meiosis
some similarities with uniprot|Q3E826 Saccharomyces cerevisiae YKL068W-A Identified by homology to Ashbya gossypii
weakly similar to uniprot|Q02629 Saccharomyces cerevisiae YKL068W NUP100 Subunit of the nuclear pore complex (NPC)
weakly similar to uniprot|Q04213 Saccharomyces cerevisiae YMR044W IOC4 Member of a complex (Isw1b) with Isw1p and Ioc2p that exhibits nucleosome-stimulated ATPase activity and acts within coding regions to coordinate transcription elongation with termination and processing contains a PWWP motif
some similarities with uniprot|P11746 Saccharomyces cerevisiae YMR043W MCM1 Transcription factor involved in cell-type-specific transcription and pheromone response plays a central role in the formation of both repressor and activator complexes
similar to uniprot|P35723 Saccharomyces cerevisiae YKL065C YET1 Endoplasmic reticulum transmembrane protein homolog of human BAP31 protein
similar to uniprot|Q04212 Saccharomyces cerevisiae YMR041C Hypothetical ORF
some similarities with uniprot|P54000 Saccharomyces cerevisiae YMR039C SUB1 Suppressor of TFIIB mutations transcriptional coactivator
similar to uniprot|P35724 Saccharomyces cerevisiae YKL064W
similar to uniprot|P40202 Saccharomyces cerevisiae YMR038C CCS1 Copper chaperone for superoxide dismutase Sod1p involved in oxidative stress protection Met-X-Cys-X2-Cys motif within the N-terminal portion is involved in insertion of copper into Sod1p under conditions of copper deprivation
similar to uniprot|P35725 Saccharomyces cerevisiae YKL063C Hypothetical ORF
weakly similar to uniprot|P33748 Saccharomyces cerevisiae YMR037C MSN2 Transcriptional activator related to Msn4p activated in stress conditions which results in translocation from the cytoplasm to the nucleus binds DNA at stress response elements of responsive genes inducing gene expression
some similarities with uniprot|P32801 Saccharomyces cerevisiae YKL048C ELM1 Serine/threonine protein kinase that regulates cellular morphogenesis septin behavior and cytokinesis required for the regulation of other kinases forms part of the bud neck ring
some similarities with uniprot|P23748 Saccharomyces cerevisiae YMR036C MIH1 Protein tyrosine phosphatase involved in cell cycle control regulates the phosphorylation state of Cdc28p homolog of S. pombe cdc25
similar to uniprot|P46972 Saccharomyces cerevisiae YMR035W IMP2 mitochondrial peptidase
similar to uniprot|Q05131 Saccharomyces cerevisiae YMR034C Hypothetical ORF
similar to uniprot|Q12496 Saccharomyces cerevisiae YOL098C Hypothetical ORF
similar to uniprot|P43548 Saccharomyces cerevisiae YFL055W AGP3 Low-affinity amino acid permease may act to supply the cell with amino acids as nitrogen source in nitrogen-poor conditions transcription is induced under conditions of sulfur limitation
weakly similar to uniprot|Q12089 Saccharomyces cerevisiae YPL005W AEP3 Peripheral mitochondrial inner membrane protein located on the matrix face of the membrane stabilizes the bicistronic AAP1-ATP6 mRNA encoding subunits 6 and 8 of the ATP synthase complex
similar to uniprot|Q12200 Saccharomyces cerevisiae YPL006W NCR1 Vacuolar membrane protein that transits through the biosynthetic vacuolar protein sorting pathway involved in sphingolipid metabolism glycoprotein homologous to human Niemann Pick C1 (NPC) protein
similar to uniprot|Q12308 Saccharomyces cerevisiae YPL007C TFC8 One of six subunits of RNA polymerase III transcription initiation factor complex (TFIIIC) part of TFIIIC TauB domain that binds BoxB promoter sites of tRNA and other genes linker between TauB and TauA domains human homolog is TFIIIC-90
similar to uniprot|P22516 Saccharomyces cerevisiae YPL008W
some similarities with uniprot|Q02606 Saccharomyces cerevisiae YPL014W Hypothetical ORF
mitochondrial 37S ribosomal protein MRPS16
highly similar to uniprot|Q02608 Saccharomyces cerevisiae YPL013C MRPS16 Mitochondrial ribosomal protein of the small subunit
similar to uniprot|Q7LH12 Saccharomyces cerevisiae YPL012W RRP12 Protein required for normal pre-rRNA Processing member of a group of seven genes whose expression is repressed during growth on glucose before and during the diauxic shift
similar to uniprot|Q12297 Saccharomyces cerevisiae YPL011C TAF3 TFIID subunit (47 kDa) involved in promoter binding and RNA polymerase II transcription initiation
similar to uniprot|P53600 Saccharomyces cerevisiae YPL010W RET3 Zeta subunit of the coatomer complex (COPI) which coats Golgi-derived transport vesicles involved in retrograde transport between Golgi and ER
similar to uniprot|Q12532 Saccharomyces cerevisiae YPL009C Hypothetical ORF
similar to uniprot|P25644 Saccharomyces cerevisiae YCR077C PAT1 Topoisomerase II-associated deadenylation-dependent mRNA-decapping factor also required for faithful chromosome transmission maintenance of rDNA locus stability and protection of mRNA 3'-UTRs from trimming functionally linked to Pab1p
weakly similar to uniprot|P25659 Saccharomyces cerevisiae YCR076C
similar to uniprot|Q3E830 Saccharomyces cerevisiae YCR075W-A Identified by homology to Ashbya gossypii
some similarities with uniprot|P40530 Saccharomyces cerevisiae YIL042C Hypothetical ORF
similar to uniprot|P17261 Saccharomyces cerevisiae YCR075C
similar to uniprot|P40528 Saccharomyces cerevisiae YIL047C SYG1 Protein for which truncation and overexpression can suppress lethality of G-alpha protein deficiency plasma membrane protein
highly similar to uniprot|P00498 Saccharomyces cerevisiae YER055C HIS1 ATP phosphoribosyltransferase a hexameric enzyme catalyzes the first step in histidine biosynthesis mutations cause histidine auxotrophy and sensitivity to Cu Co and Ni salts transcription is regulated by general amino acid control
similar to uniprot|P39014 Saccharomyces cerevisiae YIL046W MET30 F-box protein containing five copies of the WD40 motif controls cell cycle function sulfur metabolism and methionine biosynthesis as part of the ubiquitin ligase complex interacts with and regulates Met4p localizes within the nucleus
weakly similar to uniprot|P40036 Saccharomyces cerevisiae YER054C GIP2 Putative regulatory subunit of the protein phosphatase Glc7p proposed to be involved in glycogen metabolism contains a conserved motif (GVNK motif) that is also found in Gac1p Pig1p and Pig2p
similar to uniprot|P40529 Saccharomyces cerevisiae YIL044C AGE2 ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector ARF GAP with effector function(s)
some similarities with uniprot|P40312 Saccharomyces cerevisiae YNL111C CYB5 Cytochrome b5
highly similar to uniprot|P10869 Saccharomyces cerevisiae YER052C HOM3 Aspartate kinase (L-aspartate 4-P-transferase) cytoplasmic enzyme that catalyzes the first step in the common pathway for methionine and threonine biosynthesis expression regulated by Gcn4p and the general control of amino acid synthesis
similar to uniprot|P38626 Saccharomyces cerevisiae YIL043C CBR1 cytochrome b reductase
similar to uniprot|P40034 Saccharomyces cerevisiae YER051W Hypothetical ORF
some similarities with uniprot|P40537 Saccharomyces cerevisiae YIL031W ULP2 Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins
some similarities with uniprot|P40318 Saccharomyces cerevisiae YIL030C SSM4 Protein involved in mRNA turnover integral nuclear membrane protein
weakly similar to with YIL030C uniprot|P40318 Saccharomyces cerevisiae YIL030C SSM4 Protein involved in mRNA turnover integral nuclear membrane protein
weakly similar to uniprot|P14724 Saccharomyces cerevisiae YFR036W CDC26 Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C)
similar to uniprot|P40540 Saccharomyces cerevisiae YIL027C KRE27 Protein of unknown function null mutant shows K1 killer toxin resistance
similar to uniprot|P40541 Saccharomyces cerevisiae YIL026C IRR1 Subunit of the cohesin complex which is required for sister chromatid cohesion during mitosis and meiosis and interacts with centromeres and chromosome arms essential for viability
similar to uniprot|P40543 Saccharomyces cerevisiae YIL024C Hypothetical ORF
some similarities with uniprot|P38838 Saccharomyces cerevisiae YHR134W WSS1 weak suppressor of smt3
similar to uniprot|P53898 Saccharomyces cerevisiae YNL156C NSG2 Protein of unknown function potential homolog of mammalian Insig 1
highly similar to uniprot|Q9P305 Saccharomyces cerevisiae YHR132W-A Hypothetical ORF
similar to uniprot|P38836 Saccharomyces cerevisiae YHR132C
weakly similar to uniprot|P53896 Saccharomyces cerevisiae YNL158W Essential protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery
some similarities with uniprot|P53895 Saccharomyces cerevisiae YNL159C ASI2 Predicted membrane protein
similar to uniprot|Q6B1B1 Saccharomyces cerevisiae YPL060W LPE10 Mitochondrial inner membrane magnesium transporter involved in maintenance of magnesium concentrations inside mitochondria indirectly affects splicing of group II introns functionally and structurally related to Mrs2p
similar to uniprot|P38310 Saccharomyces cerevisiae YBR207W FTH1 Putative high affinity iron transporter involved in transport of intravacuolar stores of iron forms complex with Fet5p expression is regulated by iron proposed to play indirect role in endocytosis
similar to uniprot|P33413 Saccharomyces cerevisiae YHL016C DUR3 Plasma membrane urea transporter expression is highly sensitive to nitrogen catabolite repression and induced by allophanate the last intermediate of the allantoin degradative pathway