Kluyveromyces lactis strain NRRL Y-1140 chromosome D complete sequence.
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
Submitted (25-SEP-2017) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (09-SEP-2008) Genoscope - Centre National de Sequencage : BP 191 91006 EVRY cedex - FRANCE (E-mail : seqref@genoscope.cns.fr - Web : www.genoscope.cns.fr)
PROVISIONAL REFSEQ: This record has not yet been subject to final\nNCBI review. The reference sequence is identical to CR382124.\nThis is an updated version of the complete genome sequence. The\nKluyveromyces lactis sequence is made of 6 chromosomes (A to F).\nThe sequence was annotated by the Genolevures Consortium. For more\ninformation go to\nhttp://cbi.labri.fr/Genolevures.\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: INSDC submitter\nAnnotation Status :: Full annotation\nAnnotation Pipeline :: Eukaryotic Annotation Propagation Pipeline\n##Genome-Annotation-Data-END##
similar to uniprot|P36032 Saccharomyces cerevisiae YKL221W MCH2 Protein with similarity to mammalian monocarboxylate permeases which are involved in transport of monocarboxylic acids across the plasma membrane mutant is not deficient in monocarboxylate transport
uniprot|Q9Y844 Kluyveromyces lactis mal22 Maltase
highly similar to uniprot|Q9Y845 Kluyveromyces lactis mal21 Maltose permease
similar to uniprot|P24031 Saccharomyces cerevisiae YBR092C PHO3 Constitutively expressed acid phosphatase similar to Pho5p; brought to the cell surface by transport vesicles; hydrolyzes thiamin phosphates in the periplasmic space, increasing cellular thiamin uptake; expression is repressed by thiamin
some similarities with uniprot|P39712 Saccharomyces cerevisiae YAL063C
similar to uniprot|P07337 Kluyveromyces marxianus Beta- glucosidase precursor
similar to gnl|GLV|DEHA0G07139g Debaryomyces hansenii DEHA0G07139g and weakly similar to uniprot|P32466 Saccharomyces cerevisiae YDR345C HXT3 Low affinity glucose transporter of the major facilitator superfamily, expression is induced in low or high glucose conditions
some similarities with uniprot|P32800 Saccharomyces cerevisiae YJL210W PEX2 RING-finger peroxin, peroxisomal membrane protein with a C-terminal zinc-binding RING domain, forms putative translocation subcomplex with Pex10p and Pex12p which functions in peroxisomal matrix protein import
similar to uniprot|P08466 Saccharomyces cerevisiae YJL208C NUC1 Major mitochondrial nuclease has RNAse and DNA endo- and exonucleolytic activities has a role in mitochondrial recombination
similar to uniprot|P05066 Saccharomyces cerevisiae YOR386W PHR1 DNA photolyase involved in photoreactivation repairs pyrimidine dimers in the presence of visible light induced by DNA damage regulated by transcriptional repressor Rph1p
similar to uniprot|Q75C89 Ashbya gossypii ACR027C ACR027Cp and some similarities with uniprot|P28273 YKL215C Saccharomyces cerevisiae Hypothetical ORF
weakly similar to uniprot|Q08579 YOR192C Saccharomyces cerevisiae Hypothetical ORF
some similarities with uniprot|Q12090 Saccharomyces cerevisiae YLR107W REX3 RNA exonuclease; required for maturation of the RNA component of RNase MRP; functions redundantly with Rnh70p and Rex2p in processing of U5 snRNA and RNase P RNA; member of RNase D family of exonucleases
highly similar to uniprot|P41819 Saccharomyces cerevisiae YPL266W DIM1 Essential 18S rRNA dimethylase responsible for conserved m6(2)Am6(2)A dimethylation in 3'-terminal loop of 18 S rRNA part of 90S and 40S pre-particles in nucleolus involved in pre-ribosomal RNA processing
similar to uniprot|Q08981 Saccharomyces cerevisiae YPL267W ACM1 Protein of unknown function potential Cdc28p substrate
similar to uniprot|Q75C92 Ashbya gossypii ACR024W ACR024Wp and weakly similar to YPL268W uniprot|P32383 Saccharomyces cerevisiae YPL268W PLC1 Phosphoinositide-specific phospholipase C hydrolyzes phosphatidylinositol 4 5-biphosphate (PIP2) to generate inositol 1 4 5-triphosphate (IP3) and 1 2-diacylglycerol (DAG) involved in kinetochore function and pseudohyphal differentiation
highly similar to uniprot|Q04432 Saccharomyces cerevisiae YDR533C
weakly similar to uniprot|P32526 Saccharomyces cerevisiae YPL269W KAR9 Karyogamy protein required for correct positioning of the mitotic spindle and for orienting cytoplasmic microtubules localizes at the shmoo tip in mating cells and at the tip of the growing bud in small-budded cells through anaphase
similar to uniprot|P33311 Saccharomyces cerevisiae YPL270W MDL2 Half-type ATP-binding cassette (ABC) transporter of the inner mitochondrial membrane
similar to uniprot|P39985 Saccharomyces cerevisiae YEL055C
similar to uniprot|P39984 Saccharomyces cerevisiae YEL056W
similar to uniprot|Q08979 Saccharomyces cerevisiae YPL263C KEL3 Cytoplasmic protein of unknown function
similar to uniprot|P38628 Saccharomyces cerevisiae YEL058W PCM1 Essential N-acetylglucosamine-phosphate mutase a hexosephosphate mutase involved in the biosynthesis of chitin
uniprot|P78699 Kluyveromyces lactis KLLA0D00880g SOM1 Protein SOM1 mitochondrial precursor
highly similar to uniprot|P08417 Saccharomyces cerevisiae YPL262W FUM1 Fumarase converts fumaric acid to L-malic acid in the TCA cycle cytosolic and mitochondrial localization determined by the N-terminal mitochondrial targeting sequence and protein conformation
similar to uniprot|P09232 Saccharomyces cerevisiae YEL060C PRB1 Vacuolar proteinase B (yscB) a serine protease of the subtilisin family involved in protein degradation in the vacuole and required for full protein degradation during sporulation
similar to uniprot|Q12339 Saccharomyces cerevisiae YOR004W Protein required for cell viability
similar to uniprot|Q8J1G7 Ashbya gossypii ACR010C CIN8 Kinesin-like protein CIN8 and some similarites with YEL061C uniprot|P27895 Saccharomyces cerevisiae YEL061C CIN8 Kinesin motor protein involved in mitotic spindle assembly and chromosome segregation
similar to uniprot|P39923 Saccharomyces cerevisiae YEL062W NPR2 Regulator of nitrogen permeases transcription is induced in response to proline and urea contains two PEST sequences
similar to uniprot|Q08387 Saccharomyces cerevisiae YOR005C DNL4 DNA ligase required for nonhomologous end-joining (NHEJ) forms stable heterodimer with required cofactor Lif1p catalyzes DNA ligation as part of a complex with Lif1p and Nej1p involved in meiosis not essential for vegetative growth
similar to uniprot|Q12094 Saccharomyces cerevisiae YOR006C Hypothetical ORF
some similarities with uniprot|Q04257 Saccharomyces cerevisiae YML002W and some similarities with uniprot|Q04257 Saccharomyces cerevisiae YML003W Hypothetical ORF
similar to uniprot|Q12118 Saccharomyces cerevisiae YOR007C SGT2 Glutamine-rich cytoplasmic protein of unknown function contains tetratricopeptide (TPR) repeats which often mediate protein-protein interactions conserved in human and C. elegans
similar to uniprot|Q12001 Saccharomyces cerevisiae YOR002W ALG6 Glucosyltransferase involved in transfer of oligosaccharides from dolichyl pyrophosphate to asparagine residues of proteins during N-linked protein glycosylation mutations in human ortholog are associated with disease
highly similar to uniprot|P32939 Saccharomyces cerevisiae YML001W YPT7 Gtp-binding protein of the rab family required for homotypic fusion event in vacuole inheritance for endosome-endosome fusion and for fusion of endosomes to vacuoles when expressed from high copy plasmid GTP-binding protein rab family
similar to uniprot|P20052 Saccharomyces cerevisiae YOL001W PHO80 Cyclin negatively regulates phosphate metabolism Pho80p-Pho85p (cyclin-CDK complex) phosphorylates Pho4p and Swi5p deletion of PHO80 leads to aminoglycoside supersensitivity truncated form of PHO80 affects vacuole inheritance
similar to uniprot|Q12149 Saccharomyces cerevisiae YOR001W RRP6 Exonuclease component of the nuclear exosome contributes to the quality-control system that retains and degrades aberrant mRNAs in the nucleus
similar to uniprot|Q12442 Saccharomyces cerevisiae YOL002C IZH2 Membrane protein involved in zinc metabolism member of the four-protein IZH family direct target of the Zap1p transcription factor expression induced by zinc deficiency and fatty acids deletion increases sensitivity to elevated zinc
similar to uniprot|P23796 Saccharomyces cerevisiae YMR283C RIT1 Modifies initiator methionine tRNA to distinguish it from elongator methionine tRNA Initiator methionine tRNA 2'-O-ribosyl phosphate transferase
weakly similar to uniprot|P22136 Saccharomyces cerevisiae YMR282C AEP2 Mitochondrial protein likely involved in translation of the mitochondrial OLI1 mRNA exhibits genetic interaction with the OLI1 mRNA 5'-untranslated leader
similar to uniprot|Q75DZ3 Ashbya gossypii ABL120W ABL120Wp and weakly similar to YMR281W uniprot|P23797 Saccharomyces cerevisiae YMR281W GPI12 ER membrane protein involved in the second step of glycosylphosphatidylinositol (GPI) anchor assembly the de- N-acetylation of the N-acetylglucosaminylphosphatidylinositol intermediate functional homolog of human PIG-Lp
similar to uniprot|Q75DZ4 Ashbya gossypii ABL121C ABL121Cp and similar to YMR280C uniprot|P39113 Saccharomyces cerevisiae YMR280C CAT8 Zinc cluster transcriptional activator
similar to uniprot|Q03735 Saccharomyces cerevisiae YML117W NAB6 Putative RNA-binding protein based on computational analysis of large-scale protein-protein interaction data
weakly similar to uniprot|Q12303 Saccharomyces cerevisiae YLR121C YPS3 Aspartic protease
similar to uniprot|P23642 Saccharomyces cerevisiae YML115C VAN1 Mannosyltransferase with a role in protein N-glycosylation
highly similar to uniprot|Q08985 Saccharomyces cerevisiae YPL273W SAM4 S-adenosylmethionine-homocysteine methyltransferase
similar to uniprot|Q03262 Saccharomyces cerevisiae YMR278W Hypothetical ORF
similar to uniprot|Q03254 Saccharomyces cerevisiae YMR277W FCP1 Carboxy-terminal domain (CTD) phosphatase
weakly similar to uniprot|Q03750 Saccharomyces cerevisiae YML114C TAF8 TFIID subunit (65 kDa) involved in RNA polymerase II transcription initiation
similar to uniprot|Q03529 Saccharomyces cerevisiae YMR272C SCS7 Required for the hydroxylation of the very long chain fatty acid (VLCFA) located in the endoplasmic reticulum desaturase/hydroxylase enzyme
similar to uniprot|Q03759 Saccharomyces cerevisiae YML108W defines a new subfamily of the split beta-alpha-beta sandwiches.
some similarities with uniprot|P54786 Saccharomyces cerevisiae YML109W ZDS2 Protein that interacts with silencing proteins at the telomere involved in transcriptional silencing paralog of Zds1p and with YMR273C uniprot|P50111 Saccharomyces cerevisiae YMR273C ZDS1 Protein that interacts with silencing proteins at the telomere, involved in transcriptional silencing; also has a role in localization of Bcy1p, which is a regulatory subunit of protein kinase A; paralog of Zds2p
similar to uniprot|Q03530 Saccharomyces cerevisiae YMR274C RCE1 Type II CAAX prenyl protease
highly similar to uniprot|P49017 Saccharomyces cerevisiae YML110C COQ5 2-hexaprenyl-6-methoxy-1 4-benzoquinone methyltransferase involved in ubiquinone (Coenzyme Q) biosynthesis located in mitochondria
similar to uniprot|Q03758 Saccharomyces cerevisiae YML111W BUL2 Component of the Rsp5p E3-ubiquitin ligase complex involved in intracellular amino acid permease sorting functions in heat shock element mediated gene expression essential for growth in stress conditions functional homolog of BUL1
similar to uniprot|P46963 Saccharomyces cerevisiae YML112W CTK3 Gamma subunit of C-terminal domain kinase I (CTDK-I) which phosphorylates the C-terminal repeated domain of the RNA polymerase II large subunit (Rpo21p) to affect both transcription and pre-mRNA 3' end processing
similar to uniprot|P13483 Saccharomyces cerevisiae YML113W DAT1 DNA binding protein that recognizes oligo(dA). oligo(dT) tracts; Arg side chain in its N- terminal pentad Gly-Arg-Lys-Pro-Gly repeat is required for DNA-binding; not essential for viability
similar to uniprot|P48510 Saccharomyces cerevisiae YMR276W DSK2 Nuclear-enriched ubiquitin-like polyubiquitin-binding protein required for spindle pole body (SPB) duplication and for transit through the G2/M phase of the cell cycle involved in proteolysis interacts with the proteasome
weakly similar to uniprot|Q03760 Saccharomyces cerevisiae YML107C Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery
highly similar to uniprot|P13298 Saccharomyces cerevisiae YML106W URA5 Fifth step in pyrimidine biosynthesis pathway Orotate phosphoribosyltransferase 1
similar to uniprot|P29478 Saccharomyces cerevisiae YML105C SEC65 signal recognition particle subunit homologue of mammalian SRP19
similar to uniprot|Q756W7 Ashbya gossypii AER288C AER288Cp and weakly similar to YMR270C uniprot|P53437 Saccharomyces cerevisiae YMR270C RRN9 Upstream activation factor subunit
similar to uniprot|Q01846 Saccharomyces cerevisiae YML104C MDM1 Intermediate filament protein required for nuclear and mitochondrial transmission to daughter buds
similar to uniprot|P40357 Saccharomyces cerevisiae YGR009C SEC9 t-SNARE protein important for fusion of secretory vesicles with the plasma membrane
highly similar to uniprot|Q12522 Saccharomyces cerevisiae YPR016c TIF6 translation initiation factor 6 (eIF6) singleton
some similarities with uniprot|Q12495 Saccharomyces cerevisiae YPR018W RLF2 Chromatin Assembly Complex subunit 1: largest (p90) subunit of three-subunit protein complex (yeast CAF-I) involved in DNA-replication-linked nucleosome assembly. Homol. to p150 subunit human Chromatin Assembly Factor-I (CAF-I) p90 subunit of yeast Chromatin Assembly Factor-I (CAF-I)
some similarities with uniprot|P31379 Saccharomyces cerevisiae YAL018C Hypothetical ORF
highly similar to uniprot|P40970 Saccharomyces cerevisiae YDR062W LCB2 Component of serine palmitoyltransferase responsible along with Lcb1p for the first committed step in sphingolipid synthesis which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine
similar to uniprot|Q12298 Saccharomyces cerevisiae YDR061W Mitochondrial protein member of the ATP-binding cassette (ABC) transporter family transcriptionally activated by Yrm1p along with genes involved in multidrug resistance
similar to uniprot|Q03193 Saccharomyces cerevisiae YDR090C Hypothetical ORF
similar to uniprot|P36116 Saccharomyces cerevisiae YKR020W (VPS51)
weakly similar to uniprot|P47030 Saccharomyces cerevisiae YJL083W TAX4 and to uniprot|P36115 Saccharomyces cerevisiae YKR019C IRS4
similar to uniprot|P36114 Saccharomyces cerevisiae YKR018C Hypothetical ORF
similar to uniprot|P36113 Saccharomyces cerevisiae YKR017C Hypothetical ORF
similar to uniprot|P80428 Saccharomyces cerevisiae YJL081C ARP4 Nuclear actin-related protein involved in chromatin remodeling component of chromatin-remodeling enzyme complexes
similar to uniprot|P36112 Saccharomyces cerevisiae YKR016W FMP13 The authentic non-tagged protein was localized to the mitochondria
similar to uniprot|P36018 Saccharomyces cerevisiae YKR014C YPT52 rab5-like GTPase involved in vacuolar protein sorting and endocytosis probable purine nucleotide- binding protein
similar to uniprot|P06105 Saccharomyces cerevisiae YJL080C SCP160 May be required during cell division for faithful partitioning of the ER-nuclear envelope membranes involved in control of mitotic chromsome transmission
some similarities with uniprot|P36110 Saccharomyces cerevisiae YKR013W PRY2 Protein of unknown function, has similarity to Pry1p and Pry3p and to the plant PR-1 class of pathogen related proteins
some similarities with uniprot|P47032 Saccharomyces cerevisiae YJL079C PRY1 Protein of unknown function, has similarity to Pry2p and Pry3p and to the plant PR-1 class of pathogen related proteins
similar to uniprot|Q12012 Saccharomyces cerevisiae YOR289W Hypothetical ORF
similar to uniprot|Q12404 Saccharomyces cerevisiae YOR288C MPD1 Member of the protein disulfide isomerase (PDI) family
mitochondrial 54S ribosomal protein YmL23
highly similar to uniprot|Q12487 Saccharomyces cerevisiae YOR150W MRPL23 Mitochondrial ribosomal protein of the large subunit
similar to uniprot|Q06440 Saccharomyces cerevisiae YLR429W CRN1 Coronin cortical actin cytoskeletal component that associates with the Arp2p/Arp3p complex to regulate its activity
similar to uniprot|Q06436 Saccharomyces cerevisiae YLR427W MAG2 DNA-3-methyladenine glycosidase II that catalyzes of the hydrolysis of alkylated DNA
similar to uniprot|Q04969 Saccharomyces cerevisiae YML055W SPC2 Subunit of signal peptidase complex (Spc1p Spc2p Spc3p Sec11p) which catalyzes cleavage of N-terminal signal sequences of proteins targeted to the secretory pathway homologous to mammalian SPC25
similar to uniprot|Q06417 Saccharomyces cerevisiae YLR426W Hypothetical ORF
similar to uniprot|Q06412 Saccharomyces cerevisiae YLR425W TUS1 Guanine nucleotide exchange factor (GEF) that functions to modulate Rhop1 activity as part of the cell integrity signaling pathway multicopy suppressor of tor2 mutation and ypk1 ypk2 double mutation potential Cdc28p substrate
similar to uniprot|P00175 Saccharomyces cerevisiae YML054C CYB2 Cytochrome b2 (L-lactate cytochrome-c oxidoreductase) component of the mitochondrial intermembrane space required for lactate utilization expression is repressed by glucose and anaerobic conditions
highly similar to uniprot|P36015 Saccharomyces cerevisiae YKL196C YKT6 v-SNARE (synaptobrevin) essential for endoplasmic reticulum-Golgi transport
some similarities with uniprot|P36046 Saccharomyces cerevisiae YKL195W MIA40 Essential protein of the mitochondrial intermembrane space involved in import and assembly of intermembrane space proteins
weakly similar to uniprot|Q06411 Saccharomyces cerevisiae YLR424W SPP382 Essential protein present in native splicing complexes identified as a suppressor of prp38-1 a spliceosomal maturation mutation cold sensitive alleles accumulate pre-mRNA
similar to uniprot|Q06410 Saccharomyces cerevisiae YLR423C ATG17 Protein that interacts with and is required for activation of Apg1p protein kinase involved in autophagy but not in the Cvt (cytoplasm to vacuole targeting) pathway
similar to uniprot|P07236 Saccharomyces cerevisiae YKL194C MST1 Mitochondrial threonyl-tRNA synthetase
similar to uniprot|P53960 Saccharomyces cerevisiae YNL040W Hypothetical ORF
similar to uniprot|P36047 Saccharomyces cerevisiae YKL193C SDS22 Regulatory subunit of Glc7p type1 protein phosphatase
similar to uniprot|P32463 Saccharomyces cerevisiae YKL192C ACP1 Mitochondrial matrix acyl carrier protein involved in biosynthesis of octanoate which is a precursor to lipoic acid activated by phosphopantetheinylation catalyzed by Ppt2p
similar to uniprot|Q06409 Saccharomyces cerevisiae YLR422W Hypothetical ORF
similar to uniprot|O13563 Saccharomyces cerevisiae YLR421C RPN13 Subunit of the 19S regulatory particle of the 26S proteasome lid
highly similar to uniprot|P20051 Saccharomyces cerevisiae YLR420W URA4 Third step in pyrimidine biosynthesis pathway dihydrooratase
similar to uniprot|P32461 Saccharomyces cerevisiae YKL191W DPH2 Protein required along with Dph1p Kti11p Jjj3p and Dph5p for synthesis of diphthamide which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p) may act in a complex with Dph1p and Kti11p
similar to uniprot|P15365 Saccharomyces cerevisiae YJR152W DAL5 Allantoin permease ureidosuccinate permease expression is constitutive but sensitive to nitrogen catabolite repression
highly similar to uniprot|P25296 Saccharomyces cerevisiae YKL190W CNB1 Type 2B protein phosphatase regulatory B subunit of calcineurin
some similarities with uniprot|P32338 Saccharomyces cerevisiae YGR044C RME1 mediates cell type control of sporulation negatively regulates IME1 and sporulation zinc finger protein negative regulator of meiosis directly repressed by a1-a2 regulator
similar to uniprot|Q06697 Saccharomyces cerevisiae YLR418C CDC73 Substituent of the Paf1 complex together with RNA polymerase II Paf1p Hpr1p Ctr9 Leo1 Rtf1 and Ccr4p distinct from Srb-containing Pol II complexes required for the expression of certain genes and modification of some histones
similar to uniprot|Q06698 Saccharomyces cerevisiae YLR419W Hypothetical ORF
similar to uniprot|P53164 Saccharomyces cerevisiae YGL067W NPY1 NADH diphosphatase (pyrophosphatase) hydrolyzes the pyrophosphate linkage in NADH and related nucleotides localizes to peroxisomes
similar to uniprot|P29295 Saccharomyces cerevisiae YPL204W HRR25 Protein kinase involved in regulating diverse events including vesicular trafficking gene expression DNA repair and chromosome segregation binds the CTD of RNA pol II homolog of mammalian casein kinase 1delta (CK1delta)
highly similar to uniprot|P06245 Saccharomyces cerevisiae YPL203W TPK2 Involved in nutrient control of cell growth and division cAMP-dependent protein kinase catalytic subunit
putative mitochondrial 54S ribosomal protein MNP1
similar to uniprot|P53163 Saccharomyces cerevisiae YGL068W MNP1 Protein associated with the mitochondrial nucleoid
highly similar to uniprot|P27999 Saccharomyces cerevisiae YGL070C RPB9 RNA polymerase II subunit B12.6 contacts DNA mutations affect transcription start site
similar to uniprot|P22149 Saccharomyces cerevisiae YGL071W RCS1 Transcription factor involved in iron utilization and homeostasis binds the consensus site PyPuCACCCPu and activates the expression of target genes in response to changes in iron availability
weakly similar to uniprot|Q08956 Saccharomyces cerevisiae YPL201C
similar to uniprot|P10961 Saccharomyces cerevisiae YGL073W HSF1 Trimeric heat shock transcription factor activates multiple genes in response to hyperthermia recognizes variable heat shock elements
similar to uniprot|P32891 Saccharomyces cerevisiae YDL174C DLD1 D-lactate dehydrogenase oxidizes D-lactate to pyruvate transcription is heme-dependent repressed by glucose and derepressed in ethanol or lactate located in the mitochondrial inner membrane
weakly similar to uniprot|P53159 Saccharomyces cerevisiae YGL075C MPS2 Essential membrane protein localized at the nuclear envelope and spindle pole body (SPB) required for insertion of the newly duplicated SPB into the nuclear envelope potentially phosphorylated by Cdc28p
similar to uniprot|Q08954 Saccharomyces cerevisiae YPL199C Hypothetical ORF
highly similar to uniprot|P05737 Saccharomyces cerevisiae YGL076C RPL7A and to uniprot|Q12213 Saccharomyces cerevisiae YPL198W RPL7B Proteins component of the large (60S) ribosomal subunit
similar to uniprot|P32568 Saccharomyces cerevisiae YDR011W SNQ2 ABC transporter
similar to uniprot|P05316 YBR021W Saccharomyces cerevisiae FUR4 Uracil permease localized to the plasma membrane
similar to uniprot|P33302 Saccharomyces cerevisiae YOR153W PDR5 Short-lived membrane ABC (ATP-binding cassette) transporter
similar to uniprot|P29465 Saccharomyces cerevisiae YBR023C CHS3 Chitin synthase III catalyzes the transfer of N-acetylglucosamine (GlcNAc) to chitin required for synthesis of the majority of cell wall chitin the chitin ring during bud emergence and spore wall chitosan
highly similar to uniprot|Q96W94 Saccharomyces kluyveri PYD3 Beta-alanine synthase
similar to uniprot|P14180 Saccharomyces cerevisiae YBR038W CHS2 Chitin synthase II requires activation from zymogenic form in order to catalyze the transfer of N-acetylglucosamine (GlcNAc) to chitin required for the synthesis of chitin in the primary septum during cytokinesis
highly similar to uniprot|P38219 Saccharomyces cerevisiae YBR025C Hypothetical ORF
similar to uniprot|P23833 Saccharomyces cerevisiae YBR037C
highly similar to uniprot|P20604 Saccharomyces cerevisiae YDL047W SIT4 Type 2A-related serine-threonine phosphatase that functions in the G1/S transition of the mitotic cycle cytoplasmic and nuclear protein that modulates functions mediated by Pkc1p including cell wall and actin cytoskeleton organization
similar to uniprot|Q08231 Saccharomyces cerevisiae YOL072W THP1 Nuclear pore-associated protein forms a complex with Sac3p that is involved in transcription and in mRNA export from the nucleus contains a PAM domain implicated in protein- protein binding
highly similar to uniprot|P36010 Saccharomyces cerevisiae YKL067W YNK1 Nucleoside diphosphate kinase catalyzes the phosphorylation of nucleoside diphosphates into the corresponding triphosphates for nucleic acid biosynthesis
weakly similar to uniprot|P48412 Saccharomyces cerevisiae YGR072W UPF3 Component of the nonsense-mediated mRNA decay (NMD) pathway along with Nam7p and Nmd2p involved in decay of mRNA containing nonsense codons
similar to uniprot|Q02260 Saccharomyces cerevisiae YGR074W SMD1 Homolog of human core snRNP protein D1 involved in snRNA maturation U6 snRNP protein
similar to uniprot|Q00723 Saccharomyces cerevisiae YGR075C PRP38 Unique component of the U4/U6.U5 tri-snRNP particle dispensable for spliceosome assembly but required for conformational changes which lead to catalytic activation of the spliceosome
mitochondrial 54S ribosomal protein YmL25
similar to uniprot|P23369 Saccharomyces cerevisiae YGR076C MRPL25 Mitochondrial ribosomal protein of the large subunit
highly similar to uniprot|P04802 Saccharomyces cerevisiae YLL018C DPS1 Cytoplasmic aspartyl-tRNA synthetase homodimeric enzyme that catalyzes the specific aspartylation of tRNA(Asp) class II aminoacyl tRNA synthetase binding to its own mRNA may confer autoregulation
similar to uniprot|P38738 Saccharomyces cerevisiae YHL029C Cytoplasmic protein required for replication of Brome mosaic virus in S. cerevisiae which is a model system for studying replication of positive-strand RNA viruses in their natural hosts
weakly similar to uniprot|P32523 Saccharomyces cerevisiae YLL036C PRP19 Splicing factor associated with the spliceosome contains a U-box a motif found in a class of ubiquitin ligases
similar to uniprot|P38143 Saccharomyces cerevisiae YBR244W GPX2 Phospholipid hydroperoxide glutathione peroxidase induced by glucose starvation that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress
similar to uniprot|Q07872 Saccharomyces cerevisiae YLL038C ENT4 Protein of unknown function contains an N-terminal epsin- like domain
similar to uniprot|Q3E731 Saccharomyces cerevisiae YLL018C-A COX19 Cytochrome c oxidase assembly protein
highly similar to uniprot|P06106 Saccharomyces cerevisiae YLR303W MET17 O-acetyl homoserine-O-acetyl serine sulfhydrylase required for sulfur amino acid synthesis
similar to uniprot|P14772 Saccharomyces cerevisiae YLL015W BPT1 ABC type transmembrane transporter of MRP/CFTR family found in vacuolar membrane involved in the transport of unconjugated bilirubin and in heavy metal detoxification via glutathione conjugates along with Ycf1p
similar to uniprot|P38995 Saccharomyces cerevisiae YDR270W CCC2 copper-transporting P-type ATPase with similarity to human Menkes and Wilsons genes; Cu(2+)-transporting ATPase
similar to uniprot|P32457 Saccharomyces cerevisiae YLR314C CDC3 Component of the septin ring of the mother-bud neck that is required for cytokinesis septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane and they comprise the 10nm filaments seen with EM
some similarities with uniprot|Q03654 Saccharomyces cerevisiae YMR213W CEF1 Essential splicing factor; associated with Prp19p and the spliceosome, contains an N-terminal c-Myb DNA binding motif necessary for cell viability but not for Prp19p association
weakly similar to uniprot|Q12164 Saccharomyces cerevisiae YLL023C Hypothetical ORF
highly similar to uniprot|P10592 Saccharomyces cerevisiae YLL024C SSA2 member of 70 kDa heat shock protein family
similar to gnl|GLV|CAGL0J01699g Candida glabrata CAGL0J01699g
similar to uniprot|P53212 Saccharomyces cerevisiae YGR021W Hypothetical ORF
highly similar to uniprot|P39111 Saccharomyces cerevisiae YGR020C VMA7 Vacuolar H ATPase subunit F of the catalytic (V1) sector
some similarities with uniprot|Q12114 Saccharomyces cerevisiae YLR330W CHS5 Protein of unknown function involved in chitin biosynthesis by regulating Chs3p localization also involved in cell fusion during mating
highly similar to uniprot|Q00711 Saccharomyces cerevisiae YKL148C SDH1 Flavoprotein subunit of succinate dehydrogenase (Sdh1p Sdh2p Sdh3p Sdh4p) which couples the oxidation of succinate to the transfer of electrons to ubiquinone
similar to uniprot|P24309 Saccharomyces cerevisiae YKL149C DBR1 RNA lariat debranching enzyme involved in intron turnover required for efficient Ty1 transposition
similar to uniprot|P36060 Saccharomyces cerevisiae YKL150W MCR1 Mitochondrial NADH-cytochrome b5 reductase involved in ergosterol biosynthesis
similar to uniprot|P36059 Saccharomyces cerevisiae YKL151C Hypothetical ORF
similar to uniprot|P32910 Saccharomyces cerevisiae YNR003C RPC34 RNA polymerase III subunit C34 interacts with TFIIIB70 and is a key determinant in pol III recruitment by the preinitiation complex
similar to uniprot|P25371 Saccharomyces cerevisiae YCR011C ADP1 Shows homology to ATP-dependent permeases Active transport ATPase
similar to uniprot|P43599 Saccharomyces cerevisiae YFR018C Hypothetical ORF
similar to uniprot|P34756 Saccharomyces cerevisiae YFR019W FAB1 1-phosphatidylinositol-3-phosphate 5-kinase vacuolar membrane kinase that generates phosphatidylinositol (3 5)P2 which is involved in vacuolar sorting and homeostasis
similar to uniprot|P43601 Saccharomyces cerevisiae YFR021W ATG18 Phosphatidylinositol 3 5-bisphosphate-binding protein of the vacuolar membrane predicted to fold as a seven-bladed beta-propeller required for recycling of Atg9p through the pre-autophagosomal structure
similar to uniprot|Q759V0 Ashbya gossypii ADR172C ADR172Cp and weakly similar to YOR018W uniprot|Q02805 Saccharomyces cerevisiae YOR018W ROD1 Membrane protein overexpression confers resistance to the GST substrate o-dinitrobenzene as well as to zinc and calcium contains a PY-motif which is required for Rod1p interaction with Rsp5p a hect-type ubiquitin ligase
similar to uniprot|P25604 Saccharomyces cerevisiae YCL008C STP22 Component of the ESCRT-I complex which is involved in ubiquitin-dependent sorting of proteins into the endosome homologous to the mouse and human Tsg101 tumor susceptibility gene mutants exhibit a Class E Vps phenotype
some similarities with uniprot|P25386 Saccharomyces cerevisiae YDL058W USO1 involved intracellular protein transport coiled-coil protein necessary for protein transport from ER to Golgi Integrin analogue gene
uniprot|O13473 Kluyveromyces lactis CBF5 Centromere/microtubule-binding protein CBF5
similar to gnl|GLV|CAGL0H03707g Candida glabrata CAGL0H03707g and some similarites with YNL007C uniprot|P25294 Saccharomyces cerevisiae YNL007C SIS1 HSP40 family chaperone sit4 suppressor dnaJ homolog
highly similar to uniprot|P41318 Saccharomyces cerevisiae YNL006W LST8 Protein required for the transport of amino acid permease Gap1p from the Golgi to the cell surface component of the TOR signaling pathway associates with both Tor1p and Tor2p contains a WD-repeat
some similarities with uniprot|P48743 Saccharomyces cerevisiae YLR176C
similar to uniprot|P40693 Saccharomyces cerevisiae YNL002C
highly similar to uniprot|P04173 Saccharomyces cerevisiae YCL018W LEU2 Beta-isopropylmalate dehydrogenase catalyzes the third step in the leucine biosynthesis pathway
highly similar to uniprot|P25374 Saccharomyces cerevisiae YCL017C NFS1 Cysteine desulfurase involved in iron-sulfur cluster (Fe/S)biogenesis required for the post-transcriptional thio-modification of mitochondrial and cytoplasmic tRNAs essential protein located predominantly in mitochondria
similar to uniprot|P38921 Saccharomyces cerevisiae YNL003C PET8 S-adenosylmethionine transporter of the mitochondrial inner membrane member of the mitochondrial carrier family required for biotin biosynthesis and respiratory growth
similar to uniprot|P25559 Saccharomyces cerevisiae YCL016C DCC1 Subunit of a complex with Ctf8p and Ctf18p that shares some components with Replication Factor C required for sister chromatid cohesion
similar to uniprot|Q9HF61 Ashbya gossypii AAL016C BUD3 Bud site selection protein BUD3 and weakly similar to YCL014W uniprot|P25558 Saccharomyces cerevisiae YCL014W BUD3 Protein involved in bud-site selection and required for axial budding pattern localizes with septins to bud neck in mitosis and may constitute an axial landmark for next round of budding
similar to uniprot|P38922 Saccharomyces cerevisiae YNL004W
similar to uniprot|Q754A1 Ashbya gossypii AFR171W AFR171Wp and weakly similar to YDR034C uniprot|P40971 Saccharomyces cerevisiae YDR034C LYS14 Transcriptional activator involved in regulation of genes of the lysine biosynthesis pathway requires 2-aminoadipate semialdehyde as co-inducer
similar to uniprot|P53099 Saccharomyces cerevisiae YGL186C TPN1 Pyridoxine transporter
highly similar to uniprot|P04037 Saccharomyces cerevisiae YGL187C COX4 Subunit IV of cytochrome c oxidase which is the terminal member of the mitochondrial inner membrane electron transport chain N-terminal 25 residues of precursor are cleaved during mitochondrial import
highly similar to uniprot|P39938 Saccharomyces cerevisiae YGL189C
highly similar to uniprot|P15624 Saccharomyces cerevisiae YLR060W FRS1 Beta subunit of cytoplasmic phenylalanyl- tRNA synthetase, forms a tetramer with Frs2p to generate the active enzyme; evolutionarily distant from mitochondrial phenylalanyl-tRNA synthetase based on protein sequence,but substrate binding is similar and similar to gnl|GLV|YALI0E22979g
similar to uniprot|Q75BQ1 Ashbya gossypii ACR220C ACR220Cp and weakly similar to YFL034W uniprot|P43564 Saccharomyces cerevisiae YFL034W Possible integral membrane protein that interacts with Rpp0p which is a component of the ribosomal stalk
similar to uniprot|P05749 Saccharomyces cerevisiae YLR061W RPL22A Protein component of the large (60S) ribosomal subunit, has similarity to Rpl22Bp and to rat L22 ribosomal protein
similar to uniprot|Q12291 Saccharomyces cerevisiae YLR063W Hypothetical ORF
similar to uniprot|P43563 Saccharomyces cerevisiae YFL034C-B MOB2 Component of the RAM signaling network localizes and activates the Ace2p in the daughter cell nucleus to direct daughter cell-specific transcription of several genes involved in cell separation Mob1p-like protein
similar to uniprot|P13433 Saccharomyces cerevisiae YFL036W
highly similar to uniprot|P02557 Saccharomyces cerevisiae YFL037W TUB2 Beta-tubulin associates with alpha-tubulin (Tub1p and Tub3p) to form tubulin dimer which polymerizes to form microtubules
similar to uniprot|Q12144 Saccharomyces cerevisiae YLR064W Hypothetical ORF
highly similar to uniprot|P01123 Saccharomyces cerevisiae YFL038C YPT1 Ras-like small GTPase involved in the ER-to-Golgi step of the secretory pathway complex formation with the Rab escort protein Mrs6p is required for prenylation of Ypt1p by protein geranylgeranyltransferase type II (Bet2p-Bet4p)
similar to uniprot|Q6Q5C1 Saccharomyces cerevisiae YLR065C Hypothetical ORF
highly similar to uniprot|P60010 Saccharomyces cerevisiae YFL039C ACT1 Actin structural protein involved in cell polarization endocytosis and other cytoskeletal functions
weakly similar to uniprot|P43562 Saccharomyces cerevisiae YFL040W
similar to uniprot|Q12133 Saccharomyces cerevisiae YLR066W SPC3 Subunit of signal peptidase complex (Spc1p Spc2p Spc3p Sec11p) which catalyzes cleavage of N-terminal signal sequences of proteins targeted to the secretory pathway homologous to mammalian SPC22/23
similar to uniprot|P32522 Saccharomyces cerevisiae YLR067C PET309 Specific translational activator for the COX1 mRNA also influences stability of intron-containing COX1 primary transcripts located in the mitochondrial inner membrane
similar to uniprot|Q12247 Saccharomyces cerevisiae YLR068W FYV7 Protein of unknown function required for survival upon exposure to K1 killer toxin involved in processing the 35S rRNA primary transcript to generate the 20S and 27SA2 pre- rRNA transcripts
highly similar to uniprot|P25039 Saccharomyces cerevisiae YLR069C MEF1 mitochondrial elongation factor G-like protein
similar to uniprot|P43561 Saccharomyces cerevisiae YFL041W
similar to uniprot|P35497 Saccharomyces cerevisiae YJR159W SOR1 Sorbitol dehydrogenase expression is induced in the presence of sorbitol
similar to uniprot|P19263 Saccharomyces cerevisiae YLR071C RGR1 Component of RNA polymerase II holoenzyme/mediator complex affects chromatin structure and transcriptional regulation of diverse genes required for glucose repression HO repression RME1 repression and sporulation
weakly similar to uniprot|P43560 Saccharomyces cerevisiae YFL042C Due to a sequence change (deletion of G at 46151) YFL043C is now part of YFL042C
similar to uniprot|Q08003 Saccharomyces cerevisiae YLR073C Hypothetical ORF
similar to uniprot|P43558 Saccharomyces cerevisiae YFL044C YOD1 Yeast OTU Deubiquitinating enzyme 1
similar to uniprot|Q08004 Saccharomyces cerevisiae YLR074C BUD20 Protein involved in bud-site selection diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
highly similar to uniprot|P41805 Saccharomyces cerevisiae YLR075W
highly similar to uniprot|P07283 Saccharomyces cerevisiae YFL045C SEC53 involved in synthesis of GDP-mannose and dolichol-phosphate-mannose required for protein assembly in endoplasmic reticulum phosphomannomutase
highly similar to uniprot|P43557 Saccharomyces cerevisiae YFL046W FMP32 The authentic non-tagged protein was localized to the mitochondria
similar to uniprot|Q7LI62 Saccharomyces cerevisiae YLR077W FMP25 The authentic non-tagged protein was localized to the mitochondria
similar to uniprot|P25385 Saccharomyces cerevisiae YLR078C BOS1 v-SNARE (vesicle specific SNAP receptor) localized to the endoplasmic reticulum membrane and necessary for vesicular transport from the ER to the Golgi
similar to uniprot|Q75CY2 Ashbya gossypii ABR240W ABR240Wp and weakly similar to YLR079W uniprot|P38634 Saccharomyces cerevisiae YLR079W SIC1 P40 inhibitor of Cdc28p-Clb5p protein kinase complex
similar to uniprot|P43556 Saccharomyces cerevisiae YFL047W RGD2 GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p
similar to uniprot|P43555 Saccharomyces cerevisiae YFL048C EMP47 Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles which function in ER to Golgi transport
similar to uniprot|Q75CX8 Ashbya gossypii ABR244C ABR244Cp and weakly similar to YFL049W uniprot|P43554 Saccharomyces cerevisiae YFL049W Hypothetical ORF
similar to uniprot|P34251 Saccharomyces cerevisiae YKL107W Hypothetical ORF
highly similar to uniprot|P07267 Saccharomyces cerevisiae YPL154C PEP4 Vacuolar aspartyl protease (proteinase A) required for the posttranslational precursor maturation of vacuolar proteinases synthesized as a zymogen self-activates
similar to uniprot|P28743 Saccharomyces cerevisiae YPL155C KIP2 Kinesin-related motor protein involved in mitotic spindle positioning
some similarities with uniprot|Q12498 Saccharomyces cerevisiae YPL156C PRM4 Pheromone-regulated protein predicted to have 1 transmembrane segment transcriptionally regulated by Ste12p during mating and by Cat8p during the diauxic shift
similar to uniprot|Q12052 Saccharomyces cerevisiae YPL157W TGS1 TrimethylGuanosine Synthase
weakly similar to uniprot|Q99299 Saccharomyces cerevisiae YPL158C Hypothetical ORF
similar to uniprot|Q03649 Saccharomyces cerevisiae YMR210W Hypothetical ORF
weakly similar to uniprot|Q99373 Saccharomyces cerevisiae YPL159C PET20 Protein required for respiratory growth and stability of the mitochondrial genome
highly similar to uniprot|P26637 Saccharomyces cerevisiae YPL160W CDC60 Cytosolic leucyl tRNA synthetase ligates leucine to the appropriate tRNA
similar to uniprot|Q08651 Saccharomyces cerevisiae YOR246C Protein with similarity to oxidoreductases
similar to uniprot|Q03289 Saccharomyces cerevisiae YDR459C likely functions in pathway(s) outside Ras
similar to uniprot|P15274 Saccharomyces cerevisiae YML035C AMD1 AMP deaminase tetrameric enzyme that catalyzes the deamination of AMP to form IMP and ammonia may be involved in regulation of intracellular adenine nucleotide pools
similar to uniprot|P40586 Saccharomyces cerevisiae YIR042C Hypothetical ORF
similar to uniprot|P32864 Saccharomyces cerevisiae YOR370C MRS6 Rab escort protein forms a complex with the Ras-like small GTPase Ypt1p that is required for the prenylation of Ypt1p by protein geranylgeranyltransferase type II (Bet2p-Bet4p)
similar to uniprot|P40309 Saccharomyces cerevisiae YJL094C KHA1 Putative K /H antiporter
similar to uniprot|Q08873 Saccharomyces cerevisiae YOR367W
similar to uniprot|P38355 Saccharomyces cerevisiae YBR287W ZSP1
weakly similar to uniprot|P40358 Saccharomyces cerevisiae YJL073W JEM1 DnaJ-like chaperone required for nuclear membrane fusion during mating localizes to the ER membrane exhibits genetic interactions with KAR2
similar to uniprot|P37302 Saccharomyces cerevisiae YBR286W APE3 Vacuolar aminopeptidase Y processed to mature form by Prb1p
similar to uniprot|P40359 Saccharomyces cerevisiae YJL072C PSF2 Subunit of the GINS complex (Sld5p Psf1p Psf2p Psf3p) which binds to DNA replication origins and facilitates assembly of the DNA replication machinery
similar to uniprot|P40360 Saccharomyces cerevisiae YJL071W ARG2 Acetylglutamate synthase (glutamate N-acetyltransferase) mitochondrial enzyme that catalyzes the first step in the biosynthesis of the arginine precursor ornithine forms a complex with Arg5 6p
similar to uniprot|Q02933 Saccharomyces cerevisiae YPL123C RNY1 RNAse member of the T(2) family of endoribonucleases
some similarities with uniprot|P33419 Saccharomyces cerevisiae YPL124W SPC29 Inner plaque spindle pole body (SPB) component
similar to uniprot|P29461 Saccharomyces cerevisiae YOR208W PTP2 Phosphotyrosine-specific protein phosphatase involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing dephosporylates Hog1p MAPK and regulates its localization localized to the nucleus
similar to uniprot|Q02932 Saccharomyces cerevisiae YPL125W KAP120 Karyopherin with a role in the assembly or export of 60S ribosomal subunits
highly similar to uniprot|P39683 Saccharomyces cerevisiae YOR209C NPT1 Nicotinate phosphoribosyltransferase
similar to uniprot|Q02931 YPL126W Saccharomyces cerevisiae NAN1 U3 snoRNP protein component of the small (ribosomal) subunit (SSU) processosome containing U3
highly similar to uniprot|P22139 Saccharomyces cerevisiae YOR210W RPB10 RNA polymerase subunit ABC10-beta common to RNA polymerases I II and III
similar to uniprot|P32266 YOR211C Saccharomyces cerevisiae MGM1 Mitochondrial GTPase related to dynamin present in a complex containing Ugo1p and Fzo1p
weakly similar to uniprot|Q02457 YPL128C Saccharomyces cerevisiae TBF1 TTAGGG repeat binding factor
similar to uniprot|P18851 YOR212W Saccharomyces cerevisiae STE4 G protein beta subunit
similar to uniprot|Q75C19 Ashbya gossypii ACR098C ACR098Cp and some similarites with YPL129W uniprot|P35189 Saccharomyces cerevisiae YPL129W TAF14 Subunit (30 kDa) of TFIID TFIIF and SWI/SNF complexes involved in RNA polymerase II transcription initiation and in chromatin modification contains a YEATS domain
similar to uniprot|P35189 Saccharomyces cerevisiae YPL129W TAF14 Subunit(30 kDa) of TFIID, TFIIF, and SWI/SNF complexes,involved in RNA polymerase II transcription initiation and in chromatin modification, contains a YEATS domain
similar to uniprot|Q12032 YOR215C Saccharomyces cerevisiae Hypothetical ORF
similar to uniprot|Q12234 YOR216C Saccharomyces cerevisiae RUD3 Golgi matrix protein that is involved in the structural organization of the cis-Golgi
similar to uniprot|P38630 Saccharomyces cerevisiae YOR217W RFC1 Subunit of heteropentameric Replication factor C (RF-C) which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon
similar to uniprot|P33894 Saccharomyces cerevisiae YOR219C STE13 Dipeptidyl aminopeptidase Golgi integral membrane protein that cleaves on the carboxyl side of repeating -X-Ala- sequences required for maturation of alpha factor transcription is induced by a-factor
highly similar to uniprot|P26321 Saccharomyces cerevisiae YPL131W RPL5 component of the large (60S) ribosomal subunit
similar to gnl|GLV|CAGL0J04158g Candida glabrata CAGL0J04158g and weakly similar to YOR220W uniprot|Q12044 Saccharomyces cerevisiae YOR220W Hypothetical ORF
similar to uniprot|P19516 YPL132W Saccharomyces cerevisiae COX11 Mitochondrial membrane protein required for assembly of active cytochrome c oxidase
similar to uniprot|P19541 Saccharomyces cerevisiae YPL133C RDS2 Regulator of drug sensitivity Transcriptional regulator
similar to uniprot|Q12283 Saccharomyces cerevisiae YOR221C MCT1 Predicted malonyl-CoA:ACP transferase putative component of a type-II mitochondrial fatty acid synthase that produces intermediates for phospholipid remodeling
similar to uniprot|Q03028 Saccharomyces cerevisiae YPL134C ODC1 Mitochondrial inner membrane transporter exports 2-oxoadipate and 2-oxoglutarate from the mitochondrial matrix to the cytosol for use in lysine and glutamate biosynthesis and in lysine catabolism
similar to uniprot|Q12015 Saccharomyces cerevisiae YOR223W Hypothetical ORF
highly similar to uniprot|P20436 Saccharomyces cerevisiae YOR224C RPB8 RNA polymerase subunit ABC14.5 common to RNA polymerases I II and III
similar to uniprot|Q03020 Saccharomyces cerevisiae YPL135W ISU1 Conserved protein of the mitochondrial matrix
similar to uniprot|Q12276 Saccharomyces cerevisiae YOR227W Hypothetical ORF
similar to uniprot|Q12106 Saccharomyces cerevisiae Hypothetical ORF
similar to uniprot|Q03012 Saccharomyces cerevisiae YPL138C SPP1 Subunit of the COMPASS complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres
similar to gnl|GLV|CAGL0M02563g Candida glabrata CAGL0M02563g and weakly similar to uniprot|Q12206 YOR229W Saccharomyces cerevisiae WTM2 WD repeat containing transcriptional modulator 2
some similarities with uniprot|P32490 Saccharomyces cerevisiae YOR231W MKK1 Mitogen-activated kinase kinase involved in protein kinase C signaling pathway that controls cell integrity upon activation by Bck1p phosphorylates downstream target Slt2p functionally redundant with Mkk2p
similar to uniprot|P38523 YOR232W Saccharomyces cerevisiae MGE1 Protein of the mitochondrial matrix involved in protein import into mitochondria
similar to uniprot|Q03002 Saccharomyces cerevisiae YPL141C Hypothetical ORF
similar to uniprot|P40445 Saccharomyces cerevisiae YIL166C Hypothetical ORF
highly similar to uniprot|P05744 Saccharomyces cerevisiae YPL143W RPL33A Ribosomal Protein of the Large subunit
similar to uniprot|Q75BZ7 Ashbya gossypii ACR122C ACR122Cp and some similarities with YHR176W uniprot|P38866 Saccharomyces cerevisiae YHR176W FMO1 Flavin-containing monooxygenase localized to the cytoplasmic face of the ER membrane catalyzes oxidation of biological thiols to maintain the ER redox buffer ratio for correct folding of disulfide-bonded proteins
weakly similar to uniprot|Q6Q5F7 Saccharomyces cerevisiae YPL144W Hypothetical ORF
similar to uniprot|P07807 Saccharomyces cerevisiae YOR236W DFR1 Dihydrofolate reductase part of the dTTP biosynthetic pathway involved in folate metabolism possibly required for mitochondrial function
similar to uniprot|P35844 YPL145C Saccharomyces cerevisiae KES1 Member of the oxysterol binding protein family which includes seven yeast homologs involved in negative regulation of Sec14p-dependent Golgi complex secretory functions
similar to uniprot|P32908 Saccharomyces cerevisiae YFL008W SMC1 Subunit of the multiprotein cohesin complex essential protein involved in chromosome segregation and in double-strand DNA break repair SMC chromosomal ATPase family member binds DNA with a preference for DNA with secondary structure
similar to uniprot|P07834 Saccharomyces cerevisiae YFL009W CDC4 F-box protein required for G1/S and G2/M transition associates with Skp1p and Cdc53p to form a complex SCFCdc4 which acts as ubiquitin-protein ligase directing ubiquitination of the phosphorylated CDK inhibitor Sic1p
highly similar to uniprot|Q6D0Z1 Erwinia carotovora subsp ECA3657 Putative exported protein
similar to uniprot|Q750H9 Ashbya gossypii AGL028C AGL028Cp and weakly similar to YFL013C uniprot|P43579 Saccharomyces cerevisiae YFL013C IES1 Subunit of the INO80 chromatin remodeling complex
similar to uniprot|P22943 Saccharomyces cerevisiae YFL014W HSP12 Plasma membrane localized protein that protects membranes from desiccation induced by heat shock oxidative stress osmostress stationary phase entry glucose depletion oleate and alcohol regulated by the HOG and Ras-Pka pathways
similar to uniprot|P35191 Saccharomyces cerevisiae YFL016C MDJ1 Protein involved in folding of mitochondrially synthesized proteins in the mitochondrial matrix localizes to the mitochondrial inner membrane member of the DnaJ family of molecular chaperones
highly similar to uniprot|P40204 Saccharomyces cerevisiae YFL017W-A SMX2
similar to uniprot|P43577 Saccharomyces cerevisiae YFL017C GNA1 Evolutionarily conserved glucosamine-6-phosphate acetyltransferase required for multiple cell cycle events including passage through START DNA synthesis and mitosis involved in UDP-N-acetylglucosamine synthesis forms GlcNAc6P from AcCoA
weakly similar to uniprot|Q12155 Saccharomyces cerevisiae YLR050C Hypothetical ORF
similar to uniprot|P41948 Saccharomyces cerevisiae YNL142W MEP2 Ammonium permease involved in regulation of pseudohyphal growth belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4) expression is under the nitrogen catabolite repression regulation
similar to uniprot|P38842 Saccharomyces cerevisiae YHR140W Hypothetical ORF
some similarities with uniprot|P53894 Saccharomyces cerevisiae YNL161W CBK1 Protein kinase involved in cell wall biosynthesis required for efficient apical growth proper mating projection morphology bipolar bud site selection in diploid cells and cell separation
highly similar to uniprot|P02405 Saccharomyces cerevisiae YHR141C RPL42B Proteins component of the large (60S) ribosomal subunit
similar to uniprot|P38843 Saccharomyces cerevisiae YHR142W CHS7
similar to uniprot|Q3E7A8 Saccharomyces cerevisiae YNL162W-A
similar to uniprot|P53893 Saccharomyces cerevisiae YNL163C RIA1 Cytoplasmic GTPase involved in biogenesis of the 60S ribosome; has similarity to translation elongation factor 2 (Eft1p and Eft2p)
weakly similar to uniprot|P53892 Saccharomyces cerevisiae YNL164C IBD2 Component of the BUB2-dependent spindle checkpoint pathway interacts with Bfa1p and functions upstream of Bub2p and Bfa1p
some similarities with uniprot|P38844 Sacharromyces cerevisiae YHR143W
weakly similar to uniprot|P53891 Saccharomyces cerevisiae YNL165W Hypothetical ORF
similar to uniprot|P53890 Saccharomyces cerevisiae YNL166C BNI5 Protein involved in organization of septins at the mother-bud neck may interact directly with the Cdc11p septin localizes to bud neck in a septin-dependent manner
highly similar to uniprot|P40422 Saccharomyces cerevisiae YHR143W-A RPC10 RNA polymerase subunit ABC10-alpha common to RNA polymerases I II and III
weakly similar to uniprot|Q02100 Saccharomyces cerevisiae YNL167C SKO1
highly similar to uniprot|P53889 Saccharomyces cerevisiae YNL168C FMP41 The authentic non-tagged protein was localized to mitochondria
similar to uniprot|P06773 Saccharomyces cerevisiae YHR144C DCD1 Deaminase required for dCTP and dTTP synthesis expression is cell cycle regulated
similar to uniprot|P39006 Saccharomyces cerevisiae YNL169C PSD1 Phosphatidylserine decarboxylase of the mitochondrial inner membrane converts phosphatidylserine to phosphatidylethanolamine
similar to uniprot|Q754Q1 Ashbya gossypii AFR021W AFR021Wp and weakly similar to YNL172W uniprot|P53886 Saccharomyces cerevisiae YNL172W APC1 Largest subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors including mitotic cyclins during the metaphase/anaphase transition
weakly similar to uniprot|P38845 Saccharomyces cerevisiae YHR146W CRP1 Protein that binds to cruciform DNA structures
similar to uniprot|P53883 Saccharomyces cerevisiae YNL175C NOP13 Protein of unknown function, localizes to the nucleolus and nucleoplasm; contains an RNA recognition motif (RRM) and has similarity to Nop12p, which is required for processing of pre-18S rRNA
mitochondrial 54S ribosomal protein YmL22
similar to uniprot|P53881 Saccharomyces cerevisiae YNL177C MRPL22 Mitochondrial ribosomal protein of the large subunit
similar to uniprot|Q02774 Saccharomyces cerevisiae YDL212W SHR3 Endoplasmic reticulum packaging chaperone required for incorporation of amino acid permeases into COPII coated vesicles for transport to the cell surface
highly similar to uniprot|P05750 Saccharomyces cerevisiae YNL178W RPS3 Protein component of the small (40S) ribosomal subunit
similar to gnl|GLV|DEHA0F04004g Debaryomyces hansenii DEHA0F04004g and weakly similar to YNL180C uniprot|P53879 Saccharomyces cerevisiae YNL180C RHO5 Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins likely involved in protein kinase C (Pkc1p)-dependent signal transduction pathway that controls cell integrity
similar to uniprot|P53878 Saccharomyces cerevisiae YNL181W Protein required for cell viability
similar to uniprot|P53877 Saccharomyces cerevisiae YNL182C IPI3 Protein required for cell viability computational analysis of large-scale protein-protein interaction data suggests a possible role in assembly of the ribosomal large subunit
some similarities with uniprot|Q07623 Saccharomyces cerevisiae YDL213C
similar to uniprot|P22211 Saccharomyces cerevisiae YNL183C NPR1 Protein kinase that stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation
mitochondrial 54S ribosomal protein YmL19
similar to uniprot|P53875 Saccharomyces cerevisiae YNL185C MRPL19 Mitochondrial ribosomal protein of the large subunit
some similarities with uniprot|P53874 Saccharomyces cerevisiae YNL186W UBP10 Ubiquitin-specific protease that deubiquitinates ubiquitin-protein moieties may regulate silencing by acting on Sir4p involved in posttranscriptionally regulating Gap1p and possibly other transporters primarily located in the nucleus
similar to uniprot|P33327 Saccharomyces cerevisiae YDL215C GDH2 NAD()-dependent glutamate dehydrogenase degrades glutamate to ammonia and alpha-ketoglutarate expression sensitive to nitrogen catabolite repression and intracellular ammonia levels
some similarities with uniprot|Q12468 Saccharomyces cerevisiae YDL216C RRI1 subunit of COP9 signalosome (CSN) COP9 signalosome
similar to uniprot|P53873 Saccharomyces cerevisiae YNL187W Non-essential protein with putative leucine-rich nuclear export signal (NES) sequence that fits the consensus sequence recognized by Crm1p
highly similar to uniprot|Q12328 Saccharomyces cerevisiae YDL217C TIM22 Mitochondrial inner membrane protein involved in import of proteins of the ADP/ATP carrier (AAC) family
highly similar to uniprot|Q02821 Saccharomyces cerevisiae YNL189W SRP1 karyopherin alpha homolog of 60 kDa
some similarities with uniprot|P53872 Saccharomyces cerevisiae YNL190W Hypothetical ORF
weakly similar to uniprot|Q7LGR3 Saccharomyces cerevisiae YDL218W
similar to uniprot|P53871 Saccharomyces cerevisiae YNL191W Hypothetical ORF
highly similar to uniprot|Q07648 Saccharomyces cerevisiae YDL219W DTD1 D-Tyr-tRNA(Tyr) deacylase functions in protein translation may affect nonsense suppression via alteration of the protein synthesis machinery ubiquitous among eukaryotes
similar to uniprot|P16603 Saccharomyces cerevisiae YHR042W NCP1 NADP-cytochrome P450 reductase involved in ergosterol biosynthesis associated and coordinately regulated with Erg11p
similar to uniprot|Q05541 Saccharomyces cerevisiae YDR288W NSE3 Essential protein of unknown function
similar to uniprot|P40892 Saccharomyces cerevisiae YJL218W Hypothetical ORF
similar to uniprot|P29704 Saccharomyces cerevisiae YHR190W ERG9 Farnesyl-diphosphate farnesyl transferase (squalene synthase) joins two farnesyl pyrophosphate moieties to form squalene in the sterol biosynthesis pathway
similar to uniprot|Q12751 Saccharomyces cerevisiae YMR185W Protein required for cell viability
similar to uniprot|P46683 Saccharomyces cerevisiae YPL239W YAR1
similar to uniprot|P09064 Saccharomyces cerevisiae YPL237W SUI3 Beta subunit of the translation initiation factor eIF2 involved in the identification of the start codon
similar to uniprot|Q755G7 Ashbya gossypii AFL144C AFL144Cp and weakly similar to YMR184W uniprot|Q03233 Saccharomyces cerevisiae YMR184W Hypothetical ORF
weakly similar to uniprot|P38273 Saccharomyces cerevisiae YBR131W CCZ1 Protein involved in vacuolar assembly
similar to uniprot|P20424 Saccharomyces cerevisiae YPR088C SRP54 Signal recognition particle (SRP) subunit (homolog of mammalian SRP54) contains the signal sequence-binding activity of SRP interacts with the SRP RNA and mediates binding of SRP to signal receptor contains GTPase domain
some similarities with uniprot|P38272 Saccharomyces cerevisiae YBR130C SHE3 Protein that acts as an adaptor between Myo4p and the She2p-mRNA complex part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud also required for cortical ER inheritance
similar to uniprot|P38271 Saccharomyces cerevisiae YBR129C OPY1 Protein of unknown function overproduction blocks cell cycle arrest in the presence of mating pheromone
weakly similar to uniprot|Q06822 Saccharomyces cerevisiae YPR085C Protein required for cell viability
similar to uniprot|Q06821 Saccharomyces cerevisiae YPR084W Hypothetical ORF
some similarities with uniprot|P38270 Saccharomyces cerevisiae YBR128C ATG14 Subunit of an autophagy-specific phosphatidylinositol 3-kinase complex (with Vps34p Vps15p and Vps30p) required for organization of a pre-autophagosomal structure ATG14 transcription is activated by Gln3p during nitrogen starvation
highly similar to uniprot|P16140 Saccharomyces cerevisiae YBR127C VMA2 Vacuolar H ATPase regulatory subunit
similar to uniprot|Q06820 Saccharomyces cerevisiae YPR083W MDM36 Mitochondrial Distribution and Morphology
similar to uniprot|P14682 Saccharomyces cerevisiae YDR054C CDC34 Ubiquitin-conjugating enzyme or E2 together with Skp1p Rbx1p Cdc53p and an F-box protein forms a ubiquitin-protein ligase called the SCF complex which regulates cell cycle progression by targeting key substrates for degradation
weakly similar to uniprot|P28006 Saccharomyces cerevisiae YOR178C GAC1 Regulatory subunit for Glc7p (protein phosphatase I) for glycogen synthesis regulatory role also predicted for glucose repression and ion homeostasis potential Cdc28p substrate
similar to uniprot|P29496 Saccharomyces cerevisiae YLR274W CDC46 Component of the hexameric MCM complex which is important for priming origins of DNA replication in G1 and becomes an active ATP-dependent helicase that promotes DNA melting and elongation when activated by Cdc7p-Dbf4p in S-phase
highly similar to uniprot|Q06217 Saccharomyces cerevisiae YLR275W SMD2 U1 snRNP protein of the Sm class
similar to uniprot|P04821 Saccharomyces cerevisiae YLR310C CDC25 Membrane bound guanine nucleotide exchange factor (GEF or GDP-release factor) indirectly regulates adenylate cyclase through activation of Ras1p and Ras2p by stimulating the exchange of GDP for GTP required for progression through G1
similar to uniprot|P38990 Saccharomyces cerevisiae YER129W PAK1 Upstream kinase for the SNF1 complex partially redundant function with Elm1p and Tos3p members of this family of kinases have functional orthology with LKB1 a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome
highly similar to uniprot|P47079 Saccharomyces cerevisiae YJL008C CCT8 Subunit of the cytosolic chaperonin Cct ring complex related to Tcp1p required for the assembly of actin and tubulins in vivo
similar to uniprot|P47061 Saccharomyces cerevisiae YJL029C VPS53 Required for Vacuolar Protein Sorting Vps53p is a hydrophilic protein that is peripherally associated with the late Golgi and forms a stable complex with Vps52p and Vps54p.
highly similar to uniprot|P40958 Saccharomyces cerevisiae YJL030W MAD2 Component of the spindle-assembly checkpoint complex which delays the onset of anaphase in cells with defects in mitotic spindle assembly forms a complex with Mad1p
highly similar to uniprot|Q00618 Saccharomyces cerevisiae YJL031C BET4 Alpha subunit of Type II geranylgeranyltransferase required for vesicular transport between the endoplasmic reticulum and the Golgi provides a membrane attachment moiety to Rab-like proteins Ypt1p and Sec4p
similar to uniprot|P46962 Saccharomyces cerevisiae YJL006C
highly similar to uniprot|P20448 Saccharomyces cerevisiae YJL033W HCA4 Putative nucleolar DEAD box RNA helicase high-copy number suppression of a U14 snoRNA processing mutant suggests an involvement in 18S rRNA synthesis
similar to uniprot|Q07930 Saccharomyces cerevisiae YLR016C Hypothetical ORF
similar to uniprot|P16474 Saccharomyces cerevisiae YJL034W KAR2 ATPase involved in protein import into the ER also acts as a chaperone to mediate protein folding in the ER and may play a role in ER export of soluble proteins regulates the unfolded protein response via interaction with Ire1p
similar to uniprot|P38778 Saccharomyces cerevisiae YHR050W SMF2 Divalent metal ion transporter
weakly similar to uniprot|P46949 Saccharomyces cerevisiae YGR196C FYV8 Protein of unknown function required for survival upon exposure to K1 killer toxin
highly similar to uniprot|P46948 Saccharomyces cerevisiae YGR195W SKI6 superkiller ExtraCellular Mutant Ribosomal RNA Processing homolog of RNAse PH
similar to uniprot|P47088 Saccharomyces cerevisiae YJR013W GPI14 Glycosylphosphatidylinositol-alpha 1 4 mannosyltransferase I involved in GPI anchor biosynthesis requires Pbn1p for function homolog of mammalian PIG-M
weakly similar to uniprot|P47084 Saccharomyces cerevisiae YJR003C Hypothetical ORF
similar to uniprot|Q92280 Saccharomyces cerevisiae YLR002C NOC3 Protein that forms a nuclear complex with Noc2p that binds to 66S ribosomal precursors to mediate their intranuclear transport also binds to chromatin to promote the association of DNA replication factors and replication initiation
similar to uniprot|P47083 Saccharomyces cerevisiae YJR002W MPP10 Component of the SSU processome, which is required for pre-18S rRNA processing, interacts with and controls the stability of Imp3p and Imp4p, essential for viability; similar to human Mpp10p
similar to uniprot|P47082 Saccharomyces cerevisiae YJR001W AVT1 Vacuolar transporter imports large neutral amino acids into the vacuole member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters
similar to uniprot|Q07895 Saccharomyces cerevisiae YLR001C Hypothetical ORF
similar to uniprot|P32567 Saccharomyces cerevisiae YMR165C SMP2 Protein involved in respiration and plasmid maintenance
similar to uniprot|Q03829 Saccharomyces cerevisiae YMR166C Hypothetical ORF
similar to uniprot|P43122 Saccharomyces cerevisiae YDL104C
similar to uniprot|P43124 Saccharomyces cerevisiae YDL105W NSE4 Nuclear protein that plays a role in the function of the Smc5p-Rhc18p complex
similar to uniprot|Q2I041 Saccharomyces cerevisiae YMR167W MLH1 Protein required for mismatch repair in mitosis and meiosis postmeiotic segregation and spore viability forms a complex with Pms1p and Msh2p to repair mismatched DNA human homolog is associated with hereditary non-polyposis colon cancer
similar to uniprot|P40969 Saccharomyces cerevisiae YMR168C CEP3 Essential kinetochore protein component of the CBF3 complex that binds the CDEIII region of the centromere contains an N-terminal Zn2Cys6 type zinc finger domain a C-terminal acidic domain and a putative coiled coil dimerization domain
highly similar to uniprot|P47771 Saccharomyces cerevisiae YMR170C ALD2 Cytosolic aldehyde dehydrogenase that uses NAD as the preferred coenzyme expression is induced in response to high osmotic stress
similar to uniprot|P47771 Saccharomyces cerevisiae YMR170c ALD5 and to uniprot|P54114 Saccharomyces cerevisiae YMR169c ALD4
similar to uniprot|Q755L6 Ashbya gossypii AFL202C AFL202Cp and weakly similar to YDL106C uniprot|P07269 Saccharomyces cerevisiae YDL106C PHO2 Homeobox transcription factor regulatory targets include genes involved in phosphate metabolism binds cooperatively with Pho4p to the PHO5 promoter phosphorylation of Pho2p facilitates interaction with Pho4p
similar to uniprot|Q03212 Saccharomyces cerevisiae YMR171C Endosomal protein of unknown function mRNA is targeted to the bud via the mRNA transport system involving She2p
similar to uniprot|P14065 Saccharomyces cerevisiae YOR120W GCY1 Putative NADP() coupled glycerol dehydrogenase proposed to be involved in an alternative pathway for glycerol catabolism
some similarities with uniprot|P35995 Saccharomyces cerevisiae YKL222C Hypothetical ORF
similar to uniprot|P05085 Saccharomyces cerevisiae YML099C ARG81 Zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type involved in the regulation of arginine-responsive genes acts with Arg80p and Arg82p
similar to uniprot|P11747 Saccharomyces cerevisiae YML098W
similar to uniprot|Q03103 Saccharomyces cerevisiae YML130C ERO1 Glycoprotein required for oxidative protein folding in the endoplasmic reticulum
similar to uniprot|P54787 Saccharomyces cerevisiae YML097C
similar to uniprot|Q04489 Saccharomyces cerevisiae YML096W Hypothetical ORF
similar to uniprot|P06838 Saccharomyces cerevisiae YML095C RAD10 Single-stranded DNA endonuclease (with Rad1p) cleaves single-stranded DNA during nucleotide excision repair and double-strand break repair subunit of Nucleotide Excision Repair Factor 1 (NEF1) homolog of human XPF protein
highly similar to uniprot|Q04493 Saccharomyces cerevisiae YML094W GIM5 Subunit of the heterohexameric cochaperone prefoldin complex which binds specifically to cytosolic chaperonin and transfers target proteins to it
similar to uniprot|Q04500 Saccharomyces cerevisiae YML093W UTP14 Nucleolar protein component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
highly similar to uniprot|P23639 Saccharomyces cerevisiae YML092C PRE8 20S proteasome beta-type subunit
similar to uniprot|P39103 Saccharomyces cerevisiae YML129C COX14 Mitochondrial membrane protein, required for assembly of cytochrome c oxidase
similar to uniprot|Q03104 Saccharomyces cerevisiae YML128C MSC1 Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum msc1 mutants are defective in directing meiotic recombination events to homologous chromatids
similar to uniprot|Q03124 Saccharomyces cerevisiae YML127W RSC9 One of 15 subunits of the 'Remodel the Structure of Chromatin' (RSC) complex DNA-binding protein involved in the synthesis of rRNA and in transcriptional repression and activation of genes regulated by the Target of Rapamycin (TOR) pathway
similar to uniprot|Q02773 Saccharomyces cerevisiae YML091C RPM2 Protein component of mitochondrial RNase P along with the mitochondrially-encoded RNA subunit RPM1 Rnase P removes 5' extensions from tRNA precursors Rpm2p is also involved in maturation of RPM1 and in translation of mitochondrial mRNAs
highly similar to uniprot|P54839 Saccharomyces cerevisiae YML126C ERG13 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase, catalyzes the formation of HMG-CoA from acetyl-CoA and acetoacetyl-CoA; involved in the second step in mevalonate biosynthesis
similar to uniprot|P23293 Saccharomyces cerevisiae YPR161C SGV1 CDC28/cdc2 related protein kinase
similar to uniprot|P11972 Saccharomyces cerevisiae YLR452C SST2 Protein involved in desensitization to alpha-factor pheromone member of the RGS (regulator of G-protein signalling) family GTPase-activating protein
highly similar to uniprot|P32481 Saccharomyces cerevisiae YER025W GCD11 Gamma subunit of the translation initiation factor eIF2 involved in the identification of the start codon binds GTP when forming the ternary complex with GTP and tRNAi-Met
similar to uniprot|P08638 Saccharomyces cerevisiae YLR451W LEU3 Zinc-finger transcription factor that regulates genes involved in branched chain amino acid biosynthesis and ammonia assimilation positively regulated by alpha-isopropylmalate an intermediate in leucine biosynthesis
similar to uniprot|P47159 Saccharomyces cerevisiae YJR124C Hypothetical ORF
similar to uniprot|P40017 YER024W Saccharomyces cerevisiae YAT2 Carnitine acetyltransferase
highly similar to uniprot|P26783 Saccharomyces cerevisiae YJR123W
similar to uniprot|P47158 Saccharomyces cerevisiae YJR122W CAF17 Mitochondrial protein that interacts with Ccr4p in the two-hybrid system 3'-untranslated region contains a putative mRNA localization element common to genes encoding mitochondrial proteins
highly similar to uniprot|P00830 Saccharomyces cerevisiae YJR121W ATP2 Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase which is a large evolutionarily conserved enzyme complex required for ATP synthesis
highly similar to uniprot|P32263 Saccharomyces cerevisiae YER023W PRO3 Delta 1-pyrroline-5-carboxylate reductase catalyzes the last step in proline biosynthesis
similar to uniprot|P47156 Saccharomyces cerevisiae YJR119C Hypothetical ORF
similar to uniprot|P47155 Saccharomyces cerevisiae YJR118C ILM1 Protein of unknown function
similar to uniprot|P32569 Saccharomyces cerevisiae YER022W SRB4 subunit of RNA polymerase II holoenzyme/mediator complex
similar to uniprot|P40016 Saccharomyces cerevisiae YER021W
highly similar to uniprot|P47154 Saccharomyces cerevisiae YJR117W STE24 Highly conserved zinc metalloprotease that functions in two steps of a-factor maturation C-terminal CAAX proteolysis and the first step of N-terminal proteolytic processing contains multiple transmembrane spans
similar to uniprot|P47153 Saccharomyces cerevisiae YJR116W Hypothetical ORF
similar to uniprot|P47143 Saccharomyces cerevisiae YJR105W ADO1 adenosine kinase
similar to uniprot|Q75D63 Ashbya gossypii ABR160C ABR160Cp and weakly similar to YJR106W uniprot|P47144 Saccharomyces cerevisiae YJR106W ECM27 Non-essential protein of unknown function
similar to uniprot|P47145 Saccharomyces cerevisiae YJR107W Hypothetical ORF
uniprot|P54111 Kluyveromyces lactis GPA2 Guanine nucleotide-binding protein alpha-2 subunit
similar to uniprot|P53899 Saccharomyces cerevisiae YNL155W Hypothetical ORF
similar to uniprot|P53183 Saccharomyces cerevisiae YGL039W and similar to uniprot|P53111 Saccharomyces cerevisiae YGL157W and similar to uniprot|Q12068 Saccharomyces cerevisiae YOL151W and similar to uniprot|Q03049 Saccharomyces cerevisiae YDR541C NADPH-dependent Oxidoreductases
some similarities with uniprot|P23292 Saccharomyces cerevisiae YNL154C YCK2 membrane-bound casein kinase I homolog
similar to uniprot|P38840 Saccharomyces cerevisiae YHR137W ARO9 Aromatic aminotransferase catalyzes the first step of tryptophan phenylalanine and tyrosine catabolism
highly similar to uniprot|P53900 Saccharomyces cerevisiae YNL153C GIM3 Subunit of the heterohexameric cochaperone prefoldin complex which binds specifically to cytosolic chaperonin and transfers target proteins to it
highly similar to uniprot|P09624 Saccharomyces cerevisiae YFL018C LPD1 Dihydrolipoamide dehydrogenase the lipoamide dehydrogenase component (E3) of the pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase multi-enzyme complexes
similar to uniprot|Q75DH5 Ashbya gossypii ABR051C ABR051Cp and weakly similar to YMR013C uniprot|P20048 Saccharomyces cerevisiae YMR013C SEC59 Membrane protein that catalyzes the CTP-mediated phosphorylation of dolichol the terminal step in dolichyl monophosphate (Dol- P) biosynthesis required for viability normal rates of lipid intermediate synthesis and protein N-glycosylation
C/D snoRNA polycistronic Cluster 1 SNR78
C/D snoRNA polycistronic Cluster 1 SNR77
C/D snoRNA polycistronic Cluster 1 SNR76
C/D snoRNA polycistronic Cluster 1 SNR75
C/D snoRNA polycistronic Cluster 1 SNR74
C/D snoRNA polycistronic Cluster 1 SNR73
C/D snoRNA polycistronic Cluster 1 SNR72
similar to gnl|GLV|CAGL0M07678g Candida glabrata CAGL0M07678g and weakly similar to YMR014W uniprot|Q04347 Saccharomyces cerevisiae YMR014W BUD22 Protein involved in bud-site selection diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
highly similar to uniprot|P54781 Saccharomyces cerevisiae YMR015C ERG5 C-22 sterol desaturase a cytochrome P450 enzyme that catalyzes the formation of the C-22(23) double bond in the sterol side chain in ergosterol biosynthesis may be a target of azole antifungal drugs
some similarities with uniprot|Q03213 Saccharomyces cerevisiae YMR172W
similar to uniprot|O94493 Schizosaccharomyces pombe SPCC417 SPCC417.12 protein
highly similar to uniprot|P04807 Saccharomyces cerevisiae YGL253W HXK2 Hexokinase isoenzyme 2 catalyzes phosphorylation of glucose in the cytosol predominate hexokinase during growth on glucose functions in the nucleus to repress expression of HXK1 and GLK1 and to induce expression of its own gene
similar to uniprot|P32496 Saccharomyces cerevisiae YFR052W RPN12 Subunit of the 19S regulatory particle of the 26S proteasome lid synthetically lethal with RPT1 which is an ATPase component of the 19S regulatory particle physically interacts with Nob1p and Rpn3p
similar to uniprot|P43621 Saccharomyces cerevisiae YFR051C RET2 Delta subunit of the coatomer complex (COPI) which coats Golgi-derived transport vesicles involved in retrograde transport between Golgi and ER
weakly similar to uniprot|P53061 Saccharomyces cerevisiae YGL249W ZIP2 Required for 'ZIPpering' up meiotic chromosomes during chromosome synapsis involved in meiotic recombination and disjunction
similar to uniprot|P53060 Saccharomyces cerevisiae YGL250W Hypothetical ORF
similar to uniprot|P51979 Saccharomyces cerevisiae YGL251C HFM1 Meiosis specific DNA helicase involved in the conversion of double-stranded breaks to later recombination intermediates and in crossover control catalyzes the unwinding of Holliday junctions has ssDNA and dsDNA stimulated ATPase activity
highly similar to uniprot|P32608 Saccharomyces cerevisiae YGL252C RTG2 Sensor of mitochondrial dysfunction regulates the subcellular location of Rtg1p and Rtg3p transcriptional activators of the retrograde (RTG) and TOR pathways Rtg2p is inhibited by the phosphorylated form of Mks1p
highly similar to uniprot|P30657 Saccharomyces cerevisiae YFR050C PRE4 20S proteasome beta-type subunit
similar to uniprot|P22434 Saccharomyces cerevisiae YGL248W PDE1 Low-affinity cyclic AMP phosphodiesterase controls glucose and intracellular acidification-induced cAMP signaling target of the cAMP-protein kinase A (PKA) pathway glucose induces transcription and inhibits translation
similar to uniprot|P19955 Saccharomyces cerevisiae YFR049W YMR31 Mitochondrial ribosomal protein of the small subunit
similar to uniprot|P29547 Saccharomyces cerevisiae YPL048W CAM1 Translational cofactor elongation factor-1 gamma participates in the regulation of GTP-binding protein EF-1 alpha may play a redundant role in the regulation of protein synthesis or another GTP-dependent process
highly similar to uniprot|P15202 Saccharomyces cerevisiae YDR256C CTA1 Catalase A breaks down hydrogen peroxide in the peroxisomal matrix formed by acyl-CoA oxidase (Pox1p) during fatty acid beta-oxidation
similar to uniprot|Q03067 Saccharomyces cerevisiae YPL047W SGF11 11kDa subunit of the SAGA histone acetyltransferase complex involved in regulation of transcription of a subset of SAGA-regulated genes
similar to uniprot|Q12508 Saccharomyces cerevisiae YDR255C RMD5 Cytosolic protein required for sporulation also required for the ubiquitination of the gluconeogenetic enzyme fructose-1 6-bisphosphatase which is degraded rapidly after the switch from gluconeogenesis to glycolysis
similar to uniprot|O13292 Saccharomyces cerevisiae YPL046C ELC1 Elongin C forms heterodimer with Ela1p that participates in transcription elongation expression dramatically upregulated during sporulation widely conserved among eukaryotes
similar to uniprot|Q03308 Saccharomyces cerevisiae YPL045W VPS16 Vacuolar sorting protein
weakly similar to uniprot|P38907 Saccharomyces cerevisiae YDR254W CHL4 Outer kinetochore protein
similar to uniprot|P37838 Saccharomyces cerevisiae YPL043W NOP4 Nucleolar protein essential for processing and maturation of 27S pre-rRNA and large ribosomal subunit biogenesis contains four RNA recognition motifs (RRMs)
uniprot|Q70W23 Kluyveromyces lactis srb10 Cyclin-dependent protein kinase
some similarities with uniprot|Q6LE92 Saccharomyces cerevisiae YPL041C Hypothetical ORF
similar to uniprot|P48526 Saccharomyces cerevisiae YPL040C ISM1 Mitochondrial isoleucyl-tRNA synthetase null mutant is deficient in respiratory growth
some similarities with uniprot|Q03080 Saccharomyces cerevisiae YPL039W Hypothetical ORF
some similarities with uniprot|Q12041 Saccharomyces cerevisiae YDR253C MET32 and some similarities with uniprot|Q03081 Saccharomyces cerevisiae YPL038W MET31 Zinc-finger DNA-binding proteins
similar to uniprot|Q02642 Saccharomyces cerevisiae YPL037C EGD1 Subunit beta1 of the nascent polypeptide-associated complex (NAC) involved in protein targeting associated with cytoplasmic ribosomes enhances DNA binding of the Gal4p activator homolog of human BTF3b
some similarities with Saccharomyces cerevisiae YPL032C SVL3 Protein of unknown function mutant phenotype suggests a potential role in vacuolar function green fluorescent protein (GFP)-fusion protein localizes to the cell periphery cytoplasm bud and bud neck and with YDR251W uniprot|P37304 Saccharomyces cerevisiae YDR251W PAM1 Essential protein of unknown function; exhibits variable expression during colony morphogenesis; overexpression permits survival without protein phosphatase 2A, inhibits growth, and induces a filamentous phenotype
weakly similar to uniprot|Q03787 Saccharomyces cerevisiae YDR249C Hypothetical ORF
highly similar to uniprot|P17157 Saccharomyces cerevisiae YPL031C PHO85 Cyclin-dependent kinase with ten cyclin partners involved in environmental stress response in phosphate-rich conditions Pho85p-Pho80p complex phosphorylates Pho4p which in turn represses PHO5
similar to uniprot|Q2XN15 Saccharomyces cerevisiae YPL030W Hypothetical ORF
similar to uniprot|P32580 Saccharomyces cerevisiae YPL029W SUV3 ATP-dependent RNA helicase component of the mitochondrial degradosome
highly similar to uniprot|P41338 Saccharomyces cerevisiae YPL028W ERG10 Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) cytosolic enzyme that transfers an acetyl group from one acetyl-CoA molecule to another forming acetoacetyl-CoA involved in the first step in mevalonate biosynthesis
similar to uniprot|Q03786 Saccharomyces cerevisiae YDR248C Hypothetical ORF
similar to uniprot|Q12505 Saccharomyces cerevisiae YPL026C SKS1 multicopy suppressor of snf3 and grr1 mutants serine/threonine protein kinase homologous to Ran1p
similar to uniprot|Q03784 Saccharomyces cerevisiae YDR246W TRS23 Component of the targeting complex (TRAPP) involved in ER to Golgi membrane traffic
similar to uniprot|Q02685 Saccharomyces cerevisiae YPL024W RMI1 Protein of unknown function GFP tagged protein localizes to the cytoplasm and nucleus
similar to uniprot|P46151 Saccharomyces cerevisiae YPL023C MET12 Isozyme of methylenetetrahydrofolate reductase catalyzes the reduction of 5 10-methylenetetrahydrofolate to 5-methyltetrahydrofolate in the methionine biosynthesis pathway
similar to uniprot|P06777 Saccharomyces cerevisiae YPL022W RAD1 Single-stranded DNA endonuclease
some similarities with uniprot|P09547 Saccharomyces cerevisiae YPL016W SWI1 Global transcription activator that acts in complex with Snf2p Snf5p Snf6p and Swi3p to assist gene-specific activators involved in the regulation of expression of many genes including ADH1 ADH2 GAL1 HO INO1 and SUC2 Zinc-finger transcription factor
highly similar to uniprot|Q12460 Saccharomyces cerevisiae YLR197W SIK1 Component of the small (ribosomal) subunit (SSU) processosome that contains U3 snoRNA
similar to uniprot|Q05778 Saccharomyces cerevisiae YLR199C Hypothetical ORF
similar to uniprot|P52553 Saccharomyces cerevisiae YLR200W YKE2 Yeast nuclear gene
similar to uniprot|Q05779 Saccharomyces cerevisiae YLR201C FMP53
highly similar to uniprot|P32771 Saccharomyces cerevisiae YDL168W SFA1 Long-chain alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase)
some similarities with uniprot|P32770 Saccharomyces cerevisiae YDL167C NRP1
similar to uniprot|Q12055 Saccharomyces cerevisiae YDL166C FAP7 Essential nuclear protein involved in the oxidative stress response
similar to uniprot|P06100 Saccharomyces cerevisiae YDL165W CDC36 Component of the CCR4-NOT complex which has multiple roles in regulating mRNA levels including regulation of transcription and destabilizing mRNAs by deadenylation basal transcription factor
similar to uniprot|P32335 Saccharomyces cerevisiae YLR203C MSS51 Protein required for the maturation and translation of COX1 mRNA involved in maturation of COX1 and COB mRNA
some similarities with uniprot|P32344 Saccharomyces cerevisiae YLR204W QRI5
similar to uniprot|P32339 Saccharomyces cerevisiae YLR205C HMX1 ER localized, heme-binding peroxidase involved in the degradation of heme
similar to uniprot|P04819 Saccharomyces cerevisiae YDL164C CDC9 DNA ligase found in the nucleus and mitochondria an essential enzyme that joins Okazaki fragments during DNA replication also acts in nucleotide excision repair base excision repair and recombination
highly similar to uniprot|P05745 Saccharomyces cerevisiae YMR194W RPL36A and to uniprot|O14455 Saccharomyces cerevisiae YPL249C-A RPL36B Proteins component of the large (60S) ribosomal subunit
mitochondrial 54S ribosomal protein YmL24/YmL14
highly similar to uniprot|P36525 Saccharomyces cerevisiae YMR193W MRPL24 Mitochondrial ribosomal protein of the large subunit
some similarities with uniprot|Q12344 Saccharomyces cerevisiae YPL249C GYP5 GTPase-activating protein (GAP) for yeast Rab family members Ypt1p is the preferred in vitro substrate but also acts on Sec4p involved in ER to Golgi trafficking interacts with the yeast amphiphysins Rvs161p and Rvs167p
weakly similar to uniprot|P53389 Saccharomyces cerevisiae YNR055C HOL1 Putative ion transporter similar to the major facilitator superfamily of transporters; mutations in membrane-spanning domains permit nonselective cation uptake
weakly similar to uniprot|P22580 Saccharomyces cerevisiae YDR242W AMD2 Putative amidase
uniprot|P08657 Kluyveromyces lactis LAC9 Lactose regulatory protein LAC9
similar to uniprot|P35187 Saccharomyces cerevisiae YMR190C SGS1 Nucleolar DNA helicase of the RecQ family, involved in maintenance of genome integrity
similar to uniprot|P39709 Saccharomyces cerevisiae YAL067C SEO1 Putative permease member of the allantoate transporter subfamily of the major facilitator superfamily mutation confers resistance to ethionine sulfoxide
highly similar to uniprot|P49095 Saccharomyces cerevisiae YMR189W GCV2 P subunit of the mitochondrial glycine decarboxylase complex required for the catabolism of glycine to 5 10-methylene-THF expression is regulated by levels of levels of 5 10-methylene-THF in the cytoplasm
weakly similar to uniprot|Q12523 Saccharomyces cerevisiae YPL247C Hypothetical ORF
mitochondrial 37S ribosomal protein MRPS17
similar to uniprot|Q03246 Saccharomyces cerevisiae YMR188C MRPS17 Mitochondrial ribosomal protein of the small subunit
similar to uniprot|Q12270 Saccharomyces cerevisiae YPL246C RBD2 Possible rhomboid protease, has similarity to eukaryotic rhomboid proteases including Pcp1p
similar to uniprot|Q12179 Saccharomyces cerevisiae YPL245W Hypothetical ORF
similar to uniprot|Q12520 Saccharomyces cerevisiae YPL244C HUT1 Protein with a role in UDP-galactose transport to the Golgi lumen
similar to uniprot|P38687 Saccharomyces cerevisiae YPL243W SRP68 Component of the signal recognition particle (SRP) ribonucleoprotein (RNP) complex that functions in protein targeting to the endoplasmic reticulum (ER) membrane
weakly similar to uniprot|Q03236 Saccharomyces cerevisiae YMR187C Hypothetical ORF
similar to uniprot|Q12280 Saccharomyces cerevisiae YPL242C IQG1 Essential protein required for determination of budding pattern promotes localization of axial markers Bud4p and Cdc12p
weakly similar to uniprot|P46670 Saccharomyces cerevisiae YPL241C CIN2 Tubulin folding factor C (putative) involved in beta-tubulin (Tub2p) folding isolated as mutant with increased chromosome loss and sensitivity to benomyl
highly similar to uniprot|P15108 Saccharomyces cerevisiae YMR186W HSC82 Cytoplasmic chaperone of the Hsp90 family
highly similar to uniprot|P38986 Saccharomyces cerevisiae YDR321W ASP1 Cytosolic L-asparaginase involved in asparagine catabolism
highly similar to uniprot|P38795 Saccharomyces cerevisiae YHR074W QNS1 Glutamine-dependent NAD() synthetase essential for the formation of NAD() from nicotinic acid adenine dinucleotide
carboxylesterase-mitochondrial 37S ribosomal protein YmS2
similar to uniprot|P38796 Saccharomyces cerevisiae YHR075C PPE1 Protein with carboxyl methyl esterase activity that may have a role in demethylation of the phosphoprotein phosphatase catalytic subunit also identified as a small subunit mitochondrial ribosomal protein
weakly similar to uniprot|P32454 Saccharomyces cerevisiae YKL157W APE2 Zinc-dependent metallopeptidase yscII and to YHR047C uniprot|P37898 Saccharomyces cerevisiae YHR047C AAP1' Arginine/alanine aminopeptidase
mitochondrial 54S ribosomal protein YmL35
similar to uniprot|Q06678 Saccharomyces cerevisiae YDR322W MRPL35 Mitochondrial ribosomal protein of the large subunit
similar to uniprot|P81449 Saccharomyces cerevisiae YDR322C-A TIM11 Subunit e of mitochondrial F1F0-ATPase which is a large evolutionarily conserved enzyme complex required for ATP synthesis essential for the dimeric state of ATP synthase
similar to uniprot|P38797 Saccharomyces cerevisiae YHR076W PTC7 Mitochondrially localized type 2C protein phosphatase expression induced by growth on ethanol and by sustained osmotic stress possible role in carbon source utilization in low oxygen environments
similar to uniprot|P38798 Saccharomyces cerevisiae YHR077C NMD2 Protein involved in the nonsense-mediated mRNA decay (NMD) pathway interacts with Nam7p and Upf3p
similar to uniprot|P32609 Saccharomyces cerevisiae YDR323C PEP7 Multivalent adaptor protein that facilitates vesicle-mediated vacuolar protein sorting by ensuring high-fidelity vesicle docking and fusion which are essential for targeting of vesicles to the endosome required for vacuole inheritance
similar to uniprot|P38799 Saccharomyces cerevisiae YHR078W Hypothetical ORF
similar to uniprot|Q06679 Saccharomyces cerevisiae YDR324C UTP4 Nucleolar protein component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
similar to uniprot|Q06680 Saccharomyces cerevisiae YDR325W YCG1 Yeast Condensin G
similar to uniprot|P32361 Saccharomyces cerevisiae YHR079C IRE1 Serine-threonine kinase and endoribonuclease transmembrane protein that initiates the unfolded protein response signal by regulating synthesis of Hac1p through HAC1 mRNA splicing
uniprot|P18631 Kluyveromyces lactis RAG1 Low-affinity glucose transporter
similar to uniprot|Q05515 Saccharomyces cerevisiae YDR346C SVF1 Protein with a potential role in cell survival pathways required for the diauxic growth shift expression in mammalian cells increases survival under conditions inducing apoptosis
weakly similar to uniprot|P38766 Saccharomyces cerevisiae YHR031C RRM3 DNA helicase involved in rDNA replication and Ty1 transposition structurally and functionally related to Pif1p
similar to uniprot|P40549 Saccharomyces cerevisiae YIL014W MNT3 Alpha-1 3-mannosyltransferase adds the fourth and fifth alpha-1 3-linked mannose residues to O-linked glycans during protein O-glycosylation
some similarities with uniprot|P32521 YIR006C Saccharomyces cerevisiae PAN1 Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p
similar to uniprot|P40565 YIR005W Saccharomyces cerevisiae IST3 Component of the U2 snRNP required for the first catalytic step of splicing and for spliceosomal assembly
similar to uniprot|P40011 Saccharomyces cerevisiae YER010C Hypothetical ORF
similar to uniprot|P40564 YIR004W Saccharomyces cerevisiae DJP1 Cytosolic J-domain-containing protein, required for peroxisomal protein import
some similarities with uniprot|P40563 Saccharomyces cerevisiae YIR003W Hypothetical ORF
highly similar to uniprot|P33331 Saccharomyces cerevisiae YER009W NTF2 Nuclear envelope protein interacts with GDP-bound Gsp1p and with proteins of the nuclear pore to transport Gsp1p into the nucleus where it is an essential player in nucleocytoplasmic transport
some similarities with uniprot|P33332 YER008C Saccharomyces cerevisiae SEC3 Non-essential subunit of the exocyst complex (Sec3p Sec5p Sec6p Sec8p Sec10p Sec15p Exo70p Exo84p)
similar to uniprot|P40562 YIR002C Saccharomyces cerevisiae MPH1 Member of the DEAH family of helicases
similar to uniprot|P89886 YER007C-A Saccharomyces cerevisiae TMA20 Protein of unknown function that associates with ribosomes
similar to uniprot|P39937 Saccharomyces cerevisiae YER007W PAC2 Microtubule effector required for tubulin heterodimer formation binds alpha-tubulin required for normal microtubule function null mutant exhibits cold-sensitive microtubules and sensitivity to benomyl
similar to uniprot|P40010 Saccharomyces cerevisiae YER006W NUG1 GTPase that associates with nuclear 60S pre-ribosomes required for export of 60S ribosomal subunits from the nucleus
uniprot|Q05959 Kluyveromyces lactis KLLA0D13640g SUA7 Transcription initiation factor IIB
similar to uniprot|P40009 YER005W Saccharomyces cerevisiae YND1 Yeast Nucleoside Diphosphatase
similar to uniprot|P40008 Saccharomyces cerevisiae YER004W FMP52 The authentic non-tagged protein was localized to the mitochondria
highly similar to uniprot|P29952 YER003C Saccharomyces cerevisiae PMI40 mannose-6-phosphate isomerase
similar to uniprot|P40007 YER002W Saccharomyces cerevisiae NOP16 Constituent of 66S pre-ribosomal particles involved in 60S ribosomal subunit biogenesis
some similarities with uniprot|P40561 Saccharomyces cerevisiae YIR001C SGN1 Cytoplasmic RNA-binding protein contains an RNA recognition motif (RRM) may have a role in mRNA translation as suggested by genetic interactions with genes encoding proteins involved in translational initiation
similar to uniprot|P40006 Saccharomyces cerevisiae YEL001C Hypothetical ORF
similar to uniprot|P40560 YIL001W Saccharomyces cerevisiae Hypothetical ORF
similar to uniprot|P40559 YIL002C Saccharomyces cerevisiae INP51 Phosphatidylinositol 4 5-bisphosphate 5-phosphatase
similar to uniprot|P33767 YEL002C Saccharomyces cerevisiae WBP1 wheat germ agglutinin-binding protein oligosaccharyl transferase glycoprotein complex beta subunit
similar to uniprot|P40005 YEL003w Saccharomyces cerevisiae GIM4 subunit of the heterohexameric cochaperone prefoldin complex
similar to uniprot|P40004 Saccharomyces cerevisiae YEL004W
weakly similar to uniprot|P40003 Saccharomyces cerevisiae YEL005C VAB2 Protein with a potential role in vacuolar function
similar to uniprot|P40558 Saccharomyces cerevisiae YIL003W CFD1 Highly conserved putative P-loop ATPase localized in the cytoplasm has a potential role in assembly of iron-sulfur clusters in proteins
similar to uniprot|P22804 Saccharomyces cerevisiae YIL004C
similar to uniprot|P40557 YIL005W Saccharomyces cerevisiae EPS1 protein disulfide isomerase related protein involved in endoplasmic reticulum retention of resident ER proteins
similar to uniprot|P40556 Saccharomyces cerevisiae YIL006W Pvruvate transporter of the mitochondrial inner membrane member of the mitochondrial carrier family has putative mouse and human orthologs
some similarities with uniprot|P40002 Saccharomyces cerevisiae YEL007W Hypothetical ORF and some similarities with YHR177W uniprot|P38867 Saccharomyces cerevisiae YHR177W
similar to uniprot|P03069 Saccharomyces cerevisiae YEL009C GCN4 Transcriptional activator of amino acid biosynthetic genes in response to amino acid starvation expression is tightly regulated at both the transcriptional and translational levels
weakly similar to uniprot|P40555 Saccharomyces cerevisiae YIL007C NAS2 Protein with similarity to the p27 subunit of mammalian proteasome modulator not essential interacts with Rpn4p
highly similar to uniprot|P40554 YIL008W Saccharomyces cerevisiae URM1 Ubiquitin-like protein with only weak sequence similarity to ubiquitin
similar to uniprot|P06208 Saccharomyces cerevisiae YNL104C LEU4 Alpha-isopropylmalate synthase (2-isopropylmalate synthase) the main isozyme responsible for the first step in the leucine biosynthesis pathway
similar to uniprot|Q03096 Saccharomyces cerevisiae YIL009C-A EST3 Component of the telomerase holoenzyme involved in telomere replication
similar to uniprot|Q00776 Saccharomyces cerevisiae YPL259C APM1 medium subunit of the clathrin-associated protein complex
similar to uniprot|P40553 Saccharomyces cerevisiae YIL010W DOT5 Nuclear thiol peroxidase
similar to uniprot|Q08977 YPL260W Saccharomyces cerevisiae Hypothetical ORF
some similarities with uniprot|P54867 Saccharomyces cerevisiae YOR008C SLG1 Protein involved in cell wall integrity and stress response
some similarities with uniprot|P40574 Saccharomyces cerevisiae YIR018W YAP5 bZIP transcription factor
similar to uniprot|Q08193 Saccharomyces cerevisiae YOL030W GAS5 Putative 1,3-beta-glucanosyltransferase has similarity to Gas1p localizes to the cell wall
similar to uniprot|Q03677 Saccharomyces cerevisiae YMR009W ADI1 Predicted acireductone dioxygenease of the methionine salvage pathway
similar to uniprot|Q03687 YMR010W Saccharomyces cerevisiae Protein of unknown function
similar to uniprot|P32606 YOR017W Saccharomyces cerevisiae PET127 Protein with a role in mitochondrial RNA stability and/or processing
similar to uniprot|P23180 Saccharomyces cerevisiae YHL021C FMP12 The authentic non-tagged protein was localized to the mitochondria
weakly similar to uniprot|P23179 Saccharomyces cerevisiae YHL022C SPO11 Meiosis-specific protein that initiates meiotic recombination by catalyzing the formation of double-strand breaks in DNA via a transesterification reaction required for homologous chromosome pairing and synaptonemal complex formation
similar to uniprot|P39704 Saccharomyces cerevisiae YAL007C ERP2 Protein that forms a heterotrimeric complex with Erp1p Emp24p and Erv25p member along with Emp24p and Erv25p of the p24 family involved in ER to Golgi transport and localized to COPII-coated vesicles
similar to uniprot|Q06103 Saccharomyces cerevisiae YPR108W
similar to uniprot|P06115 Saccharomyces cerevisiae YGR088W CTT1 Cytosolic catalase T has a role in protection from oxidative damage by hydrogen peroxide
similar to uniprot|P53253 Saccharomyces cerevisiae YGR089W NNF2 Protein that exhibits physical and genetic interactions with Rpb8p which is a subunit of RNA polymerases I II and III computational analysis of large-scale protein-protein interaction data suggests a role in chromosome segregation
similar to uniprot|P53254 Saccharomyces cerevisiae YGR090W UTP22 Possible U3 snoRNP protein involved in maturation of pre-18S rRNA based on computational analysis of large-scale protein-protein interaction data
highly similar to uniprot|P07703 Saccharomyces cerevisiae YPR110C RPC40 RNA polymerase subunit common to RNA polymerase I and III
weakly similar to uniprot|P49704 Saccharomyces cerevisiae YGR091W PRP31 Splicing factor component of the U4/U6-U5 snRNP complex
similar to uniprot|P22204 Saccharomyces cerevisiae YGR092W DBF2 Ser/Thr kinase involved in transcription and stress response functions as part of a network of genes in exit from mitosis localization is cell cycle regulated activated by Cdc15p during the exit from mitosis
similar to uniprot|P53255 Saccharomyces cerevisiae YGR093W Hypothetical ORF
similar to uniprot|Q06106 Saccharomyces cerevisiae YPR112C MRD1 Essential conserved protein that associates with 35S precursor rRNA and is required for its initial processing at the A(0)-A(2) cleavage sites shows partial nucleolar localization contains five consensus RNA-binding domains
highly similar to uniprot|P07806 Saccharomyces cerevisiae YGR094W VAS1 mitochondrial and cytoplasmic valyl-tRNA synthetase
similar to uniprot|P53256 Saccharomyces cerevisiae YGR095C RRP46 Ribosomal RNA Processing Putative 3'->5' exoribonuclease component of exosome complex of 3'->5' exonucleases
similar to uniprot|P53257 Saccharomyces cerevisiae YGR096W TPC1 Tpc1p is a transporter that catalyzes the uptake of the essential cofactor thiamine pyrophosphate (ThPP) into mitochondria it is located in the mitochondrial membrane and its expression appears to be regulated by carbon source
similar to uniprot|P06197 Saccharomyces cerevisiae YPR113W PIS1 Phosphatidylinositol synthase required for biosynthesis of phosphatidylinositol which is a precursor for polyphosphoinositides sphingolipids and glycolipid anchors for some of the plasma membrane proteins
similar to uniprot|Q06107 Saccharomyces cerevisiae YPR114W Hypothetical ORF
some similarities with Saccharomyces cerevisiae YPR115W Hypothetical ORF and to YGR097W uniprot|P48361 Saccharomyces cerevisiae YGR097W ASK10 Component of the RNA polymerase II holoenzyme phosphorylated in response to oxidative stress has a role in destruction of Ssn8p which relieves repression of stress-response genes
weakly similar to uniprot|Q06109 Saccharomyces cerevisiae YPR116W Hypothetical ORF
similar to uniprot|Q03018 Saccharomyces cerevisiae YGR098C ESP1 Separase with cysteine protease activity (related to caspases) that promotes sister chromatid separation by mediating dissociation of the cohesin Scc1p from chromatin inhibited by Pds1p
similar to uniprot|P53038 Saccharomyces cerevisiae YGR099W TEL2 Essential DNA-binding protein specific to single-stranded yeast telomeric DNA repeats required for telomere length regulation and telomere position effect
weakly similar to uniprot|Q06116 Saccharomyces cerevisiae YPR117W Hypothetical ORF
similar to uniprot|P53258 Saccharomyces cerevisiae YGR100W MDR1 Cytoplasmic GTPase-activating protein for Ypt/Rab transport GTPases Ypt6p Ypt31p and Sec4p involved in recycling of internalized proteins and regulation of Golgi secretory function
similar to uniprot|P53259 Saccharomyces cerevisiae YGR101W PCP1 Mitochondrial serine protease required for the processing of various mitochondrial proteins and maintenance of mitochondrial DNA and morphology belongs to the rhomboid-GlpG superfamily of intramembrane peptidases
similar to uniprot|P53260 Saccharomyces cerevisiae YGR102C Hypothetical ORF
similar to uniprot|P53261 Saccharomyces cerevisiae YGR103W NOP7 Nucleolar protein involved in rRNA processing and 60S ribosomal subunit biogenesis constituent of several different pre-ribosomal particles
similar to uniprot|P32585 Saccharomyces cerevisiae YGR104C SRB5 subunit of RNA polymerase II holoenzyme/mediator complex
similar to uniprot|P41806 Saccharomyces cerevisiae YGR105W VMA21 Protein involved in vacuolar H -ATPase assembly or function required for the biogenesis of a functional vacuolar ATPase (V-ATPase) but not part of the final enzyme complex
weakly similar to uniprot|P53262 Saccharomyces cerevisiae YGR106C Hypothetical ORF
some similarities with uniprot|P21657 Saccharomyces cerevisiae YIR023W DAL81 Positive regulator of genes in multiple nitrogen degradation pathways
similar to uniprot|Q06593 Saccharomyces cerevisiae YPR194C OPT2 Oligopeptide transporter member of the OPT family with potential orthologs in S. pombe and C. albicans
weakly similar to uniprot|Q0CQA0 Aspergillus terreus NIH2624 ATEG_04134 Predicted protein
similar to uniprot|Q06489 Saccharomyces cerevisiae YPR118W Methylthioribose-1-phosphate isomerase catalyzes the isomerization of 5-methylthioribose-1-phosphate to 5-methylthioribulose-1-phosphate in the methionine salvage pathway
similar to uniprot|P32573 Saccharomyces cerevisiae YNL202W SPS19 late sporulation specific gene which may function during spore wall formation; peroxisomal 2,4-dienoyl-CoA reductase
similar to uniprot|P24869 Saccharomyces cerevisiae YPR119W CLB2 Involved in mitotic induction G(sub)2-specific B-type cyclin and uniprot|P24868 Saccharomyces cerevisiae YGR108W CLB1
similar to uniprot|P30283 Saccharomyces cerevisiae YPR120C CLB5 B-type cyclin with a role in DNA replication during S phase has an additional functional role in formation of mitotic spindles along with Clb3p and Clb4p and uniprot|P32943 Saccharomyces cerevisiae YGR109C CLB6
similar to uniprot|P40851 Saccharomyces cerevisiae YPR122W AXL1 Haploid specific endoprotease that performs one of two N-terminal cleavages during maturation of a-factor mating pheromone required for axial budding pattern of haploid cells
similar to uniprot|P53265 Saccharomyces cerevisiae YGR111W Hypothetical ORF
highly similar to YBR252W, uniprot|P33317 Saccharomyces cerevisiae YBR252W (DUT1)
similar to uniprot|P32570 Saccharomyces cerevisiae YBR253W SRB6 Protein involved in transcription as part of the Srb/Mediator complex
weakly similar to uniprot|P40568 Saccharomyces cerevisiae YIR010W DSN1 Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to those contacting microtubules important for chromosome segregation
similar to uniprot|P38334 Saccharomyces cerevisiae YBR254C TRS20 Trapp subunit of 20 kDa probable membrane protein mutations in the human homolog cause spondyloepiphyseal dysplasia tarda (SEDL) a genetically heterogeneous disorder characterized by short stature and early-onset osteoarthritis
some similarities with uniprot|P38335 Saccharomyces cerevisiae YBR255W Protein of unknown function required for normal growth rate at 15 degrees C green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
similar to uniprot|Q3E776 Saccharomyces cerevisiae YBR255C-A Hypothetical ORF identified by homology
some similarities with uniprot|P38637 Saccharomyces cerevisiae YIR011C STS1 Protein that interacts with the karyopherin Srp1p
similar to uniprot|P35184 Saccharomyces cerevisiae YIR012W SQT1 Protein involved in a late step of 60S ribosomal subunit assembly or modification contains multiple WD repeats interacts with Qsr1p in the two-hybrid system
highly similar to uniprot|P38145 Saccharomyces cerevisiae YBR256C RIB5 Riboflavin synthase catalyzes the last step of the riboflavin biosynthesis pathway
some similarities with uniprot|P12630 Saccharomyces cerevisiae YIL015W BAR1 Aspartyl protease secreted into the periplasmic space of mating type a cells, cleaves and inactivates alpha factor allowing cells to recover from alpha-factor-induced cell cycle arrest and to YLR121C uniprot|Q12303 Saccharomyces cerevisiae YLR121C YPS3 Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor and to YLR120C uniprot|P32329 Saccharomyces cerevisiae YLR120C YPS1 Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor and to YDR144C uniprot|P53379 Saccharomyces cerevisiae YDR144C MKC7 GPI-anchored aspartyl protease (yapsin) involved in protein processing; shares functions with Yap3p and Kex2p and to YIR039C uniprot|P40583 Saccharomyces cerevisiae YIR039C YPS6 Putative GPI-anchored aspartic protease
weakly similar to uniprot|P40547 Saccharomyces cerevisiae YIL017C VID28 Vacuole import and degradation
similar to uniprot|P39692 Saccharomyces cerevisiae YFR030W MET10 Subunit alpha of assimilatory sulfite reductase which is responsible for the conversion of sulfite into sulfide
similar to uniprot|P38989 Saccharomyces cerevisiae YFR031C SMC2 Component of the condensin complex essential SMC chromosomal ATPase family member that forms a complex with Smc4p to form the active ATPase Smc2p/Smc4p complex binds DNA possibly in the cleft formed by the coiled-coil of the folded dimer
highly similar to uniprot|P05736 Saccharomyces cerevisiae YIL018W RPL2B and highly similar to uniprot|P05736 Saccharomyces cerevisiae YFR031C-A RPL2A, Protein component of the large (60S) ribosomal subunit
some similarities with uniprot|P43607 Saccharomyces cerevisiae YFR032C Hypothetical ORF
highly similar to uniprot|P05747 Saccharomyces cerevisiae YFR032C-A RPL29 Protein component of the large (60S) ribosomal subunit
weakly similar to uniprot|P00127 Saccharomyces cerevisiae YFR033C QCR6 ubiquinol-cytochrome c oxidoreductase subunit 6 (17 kDa)
similar to uniprot|P40546 Saccharomyces cerevisiae YIL019W FAF1 Protein required for pre-rRNA processing and 40S ribosomal subunit assembly
highly similar to uniprot|P40545 Saccharomyces cerevisiae YIL020C HIS6 Phosphoribosyl-5-amino-1-phosphoribosyl-4- imidazolecarboxiamide isomerase catalyzes the fourth step in histidine biosynthesis mutations cause histidine auxotrophy and sensitivity to Cu Co and Ni salts
highly similar to uniprot|P16370 Saccharomyces cerevisiae YIL021W
highly similar to uniprot|Q01852 Saccharomyces cerevisiae YIL022W TIM44 48.8 kDa protein involved in mitochondrial protein import
weakly similar to uniprot|P53278 Saccharomyces cerevisiae YGR130C Protein of unknown function green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
similar to uniprot|Q12207 Saccharomyces cerevisiae YPR149W NCE102 and to uniprot|P53279 Saccharomyces cerevisiae YGR131W
similar to uniprot|P40961 Saccharomyces cerevisiae YGR132C
weakly similar to uniprot|Q7LGV7 Saccharomyces cerevisiae YLR127C
similar to uniprot|Q12395 Saccharomyces cerevisiae YLR128W DCN1 Hypothetical ORF
similar to uniprot|Q03761 Saccharomyces cerevisiae YDR145W
similar to uniprot|Q12220 Saccharomyces cerevisiae YLR129W DIP2 Nucleolar protein specifically associated with the U3 snoRNA part of the large ribonucleoprotein complex known as the small subunit (SSU) processome required for 18S rRNA biogenesis part of the active pre- rRNA processing complex
highly similar to uniprot|P11986 Saccharomyces cerevisiae YJL153C INO1 Inositol 1-phosphate synthase involved in synthesis of inositol phosphates and inositol-containing phospholipids transcription is coregulated with other phospholipid biosynthetic genes by Ino2p and Ino4p which bind the UASINO DNA element
similar to uniprot|Q12436 Saccharomyces cerevisiae YLR130C ZRT2 Low-affinity zinc transporter of the plasma membrane transcription is induced under low-zinc conditions by the Zap1p transcription factor
weakly similar to uniprot|P21192 Saccharomyces cerevisiae YLR131C ACE2 Transcription factor that activates expression of early G1-specific genes localizes to daughter cell nuclei after cytokinesis and delays G1 progression in daughters localization is regulated by phosphorylation potential Cdc28p substrate
weakly similar to uniprot|Q12208 Saccharomyces cerevisiae YLR132C Protein required for cell viability
similar to uniprot|P20485 Saccharomyces cerevisiae YLR133W CKI1 choline kinase
some similarities with uniprot|P19262 Saccharomyces cerevisiae YDR148C KGD2 Dihydrolipoyl transsuccinylase a component of the mitochondrial alpha-ketoglutarate dehydrogenase complex which catalyzes a step in the tricarboxylic acid (TCA) cycle the oxidative decarboxylation of alpha-ketoglutarate to succinyl-CoA
weakly similar to uniprot|Q12098 Saccharomyces cerevisiae YLR135W SLX4 Subunit of a complex with Slx1p that hydrolyzes 5' branches from duplex DNA in response to stalled or converging replication forks function overlaps with that of Sgs1p-Top3p
weakly similar to uniprot|Q00402 Saccharomyces cerevisiae YDR150W NUM1 Protein required for nuclear migration localizes to the mother cell cortex and the bud tip may mediate interactions of dynein and cytoplasmic microtubules with the cell cortex
similar to uniprot|P47161 Saccharomyces cerevisiae YJR126C
similar to uniprot|P47976 Saccharomyces cerevisiae YDR151C
similar to uniprot|Q03768 Saccharomyces cerevisiae YDR152W GIR2 RWD domain containing protein of unknown function
similar to uniprot|Q6Q5U2 Saccharomyces cerevisiae YDR153C ENT5 Protein containing an N-terminal epsin-like domain involved in clathrin recruitment and traffic between the Golgi and endosomes associates with the clathrin adaptor Gga2p clathrin adaptor complex AP-1 and clathrin
highly similar to uniprot|P14832 Saccharomyces cerevisiae YDR155C CPR1 Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin) catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues binds the drug cyclosporin A
similar to uniprot|P50106 Saccharomyces cerevisiae YDR156W RPA14 RNA polymerase I subunit A14
highly similar to uniprot|P13663 Saccharomyces cerevisiae YDR158W HOM2 Aspartic beta semi-aldehyde dehydrogenase catalyzes the second step in the common pathway for methionine and threonine biosynthesis expression regulated by Gcn4p and the general control of amino acid synthesis
similar to uniprot|Q12367 Saccharomyces cerevisiae YLR137W Hypothetical ORF
similar to uniprot|P46674 Saccharomyces cerevisiae YDR159W SAC3 Nuclear pore-associated protein forms a complex with Thp1p that is involved in transcription and in mRNA export from the nucleus
similar to uniprot|Q99271 Saccharomyces cerevisiae YLR138W
similar to uniprot|Q03770 Saccharomyces cerevisiae YDR160W SSY1 Component of the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p) which senses external amino acid concentration and transmits intracellular signals that result in regulation of expression of amino acid permease genes
similar to uniprot|Q03771 Saccharomyces cerevisiae YDR161W interacts with PP2C
similar to uniprot|Q12163 Saccharomyces cerevisiae YDR162C NBP2 Protein involved in the HOG (high osmolarity glycerol) pathway negatively regulates Hog1p by recruitment of phosphatase Ptc1p the Pbs2p-Hog1p complex found in the nucleus and cytoplasm contains an SH3 domain that binds Pbs2p
similar to uniprot|Q03772 Saccharomyces cerevisiae YDR163W CWC15 Non-essential protein involved in pre-mRNA splicing, component of a complex containing Cef1p; has similarity to S. pombe Cwf15p
weakly similar to uniprot|P42900 Saccharomyces cerevisiae YLR139C SLS1 Mitochondrial membrane protein required for assembly of respiratory-chain enzyme complexes III and IV coordinates expression of mitochondrially-encoded genes may facilitate delivery of mRNA to membrane-bound translation machinery
weakly similar to uniprot|Q02983 Saccharomyces cerevisiae YLR141W RRN5 Transcription factor member of UAF (upstream activation factor) family along with Rrn9p and Rrn10p involved in transcription of rDNA by RNA polymerase I
similar to uniprot|P09368 Saccharomyces cerevisiae YLR142W PUT1 proline oxidase
similar to uniprot|Q07261 Saccharomyces cerevisiae YLR143W Hypothetical ORF
similar to uniprot|P30619 Saccharomyces cerevisiae YDR164C SEC1 Sm-like protein involved in docking and fusion of exocytic vesicles through binding to assembled SNARE complexes at the membrane localization to sites of secretion (bud neck and bud tip) is dependent on SNARE function
similar to uniprot|Q07268 Saccharomyces cerevisiae YLR144C ACF2 Intracellular beta-1 3-endoglucanase expression is induced during sporulation may have a role in cortical actin cytoskeleton assembly
weakly similar to uniprot|Q12530 Saccharomyces cerevisiae YLR145W RMP1 Protein required for cell viability component of RNase MRP which is involved in RNA processing in mitochondria
similar to uniprot|Q12455 Saccharomyces cerevisiae YLR146C SPE4 Spermine Synthase
similar to uniprot|Q03774 Saccharomyces cerevisiae YDR165W TRM82 Subunit of a tRNA methyltransferase complex composed of Trm8p and Trm82p that catalyzes 7-methylguanosine modification of tRNA
similar to uniprot|P89102 Saccharomyces cerevisiae YDR166C SEC5 Essential 107kDa subunit of the exocyst complex (Sec3p Sec5p Sec6p Sec8p Sec10p Sec15p Exo70p and Exo84p) which has the essential function of mediating polarized targeting of secretory vesicles to active sites of exocytosis
similar to uniprot|P43321 Saccharomyces cerevisiae YLR147C SMD3 involved in snRNP biogenesis and pre-mRNA splicing encodes a core snRNP protein
similar to uniprot|P27801 Saccharomyces cerevisiae YLR148W PEP3 Vacuolar peripheral membrane protein that promotes vesicular docking/fusion reactions in conjunction with SNARE proteins required for vacuolar biogenesis forms complex with Pep5p that mediates protein transport to the vacuole
similar to uniprot|Q12030 Saccharomyces cerevisiae YDR167W TAF10 Subunit (145 kDa) of TFIID and SAGA complexes involved in RNA polymerase II transcription initiation and in chromatin modification
similar to uniprot|P06101 Saccharomyces cerevisiae YDR168W CDC37 Essential Hsp90p co-chaperone necessary for passage through the START phase of the cell cycle
similar to uniprot|Q99296 Saccharomyces cerevisiae YLR149C Hypothetical ORF
weakly similar to uniprot|Q12427 Saccharomyces cerevisiae YDR169C STB3 Protein that binds Sin3p in a two-hybrid assay
similar to uniprot|Q12524 Saccharomyces cerevisiae YLR151C PCD1 Peroxisomal nudix pyrophosphatase with specificity for coenzyme A and CoA derivatives may function to remove potentially toxic oxidized CoA disulfide from peroxisomes to maintain the capacity for beta-oxidation of fatty acids
similar to uniprot|P54072 Saccharomyces cerevisiae YLR152C Hypothetical ORF
uniprot|Q9Y7B5 Kluyveromyces lactis KLLA0D17336g ACS2 Acetyl-coenzyme A synthetase 2
similar to uniprot|P11075 Saccharomyces cerevisiae YDR170C SEC7 Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors involved in proliferation of the Golgi intra-Golgi transport and ER-to-Golgi transport found in the cytoplasm and on Golgi-associated coated vesicles
highly similar to uniprot|Q6YFE5 Saccharomyces kluyveri GTP cyclohydrolase
similar to uniprot|P07250 Saccharomyces cerevisiae YDR173C ARG82 Protein involved in regulation of arginine-responsive and Mcm1p-dependent genes has a dual-specificity inositol polyphosphate kinase activity required for regulation of phosphate- and nitrogen- responsive genes
uniprot|Q9HGI8 Kluyveromyces lactis KLLA0D17424g SUP35 Eukaryotic peptide chain release factor GTP-binding subunit
similar to uniprot|Q12329 Saccharomyces cerevisiae YDR171W HSP42 Small cytosolic stress-induced chaperone that forms barrel-shaped oligomers and suppresses the aggregation of non-native proteins oligomer dissociation is not required for function involved in cytoskeleton reorganization after heat shock
some similarities with uniprot|Q8TGM6 Saccharomyces cerevisiae YLR154W-C TAR1, Mitochondrial protein of unknown function, encoded within the 25S rRNA gene on the opposite strand
similar to uniprot|Q03973 Saccharomyces cerevisiae YDR174W HMO1 Chromatin associated high mobility group (HMG) family member involved in genome maintenance rDNA- binding component of the Pol I transcription system associates with a 5'-3' DNA helicase and Fpr1p a prolyl isomerase
mitochondrial 37S ribosomal protein RSM24
similar to uniprot|Q03976 Saccharomyces cerevisiae YDR175C RSM24 Mitochondrial ribosomal protein of the small subunit
similar to uniprot|P32494 Saccharomyces cerevisiae YDR176W NGG1 Transcriptional regulator involved in glucose repression of Gal4p-regulated genes component of transcriptional adaptor and histone acetyltransferase complexes the ADA complex the SAGA complex and the SLIK complex
highly similar to uniprot|P10507 Saccharomyces cerevisiae YLR163C MAS1 Smaller subunit of the mitochondrial processing protease essential processing enzyme that cleaves the N-terminal targeting sequences from mitochondrially imported proteins
similar to uniprot|P37298 Saccharomyces cerevisiae YDR178W SDH4 Membrane anchor subunit of succinate dehydrogenase (Sdh1p Sdh2p Sdh3p Sdh4p) which couples the oxidation of succinate to the transfer of electrons to ubiquinone
similar to uniprot|Q03981 Saccharomyces cerevisiae YDR179C CSN9 Subunit of the Cop9 signalosome, which is required for deneddylation, or removal of the ubiquitin-like protein Rub1p from Cdc53p (cullin); involved in adaptation to pheromone signaling
some similarities with uniprot|Q03984 Saccharomyces cerevisiae YDR179W-A Hypothetical ORF
similar to uniprot|Q06244 Saccharomyces cerevisiae YLR165C PUS5
similar to uniprot|Q04002 Saccharomyces cerevisiae YDR180W SCC2 Sister chromatid cohesion protein
weakly similar to uniprot|Q04003 Saccharomyces cerevisiae YDR181c SAS4 involved in silencing at telomere
similar to uniprot|P40986 Saccharomyces cerevisiae YDR182W CDC1 Putative membrane protein of unknown function involved in Mn2 homeostasis mutants display actin and general growth defects heterogeneous cell cycle arrests and pleiotropic defects in cell cycle progression and organelle distribution
similar to uniprot|Q06245 Saccharomyces cerevisiae YLR166C SEC10 Essential 100kDa subunit of the exocyst complex (Sec3p Sec5p Sec6p Sec8p Sec10p Sec15p Exo70p and Exo84p) which has the essential function of mediating polarized targeting of secretory vesicles to active sites of exocytosis
weakly similar to uniprot|Q04004 Saccharomyces cerevisiae YDR183W
ubiquitin-40S ribosomal protein S31 fusion protein
similar to uniprot|P04838 Saccharomyces cerevisiae YLR167W RPS31 Fusion protein that is cleaved to yield a ribosomal protein of the small (40S) subunit and ubiquitin; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes; interacts genetically with translation factor eIF2B
uniprot|Q6CQB7 Kluyveromyces lactis KLLA0D18326g ATC1 Protein ATC1/LIC4
similar to uniprot|P35200 Saccharomyces cerevisiae YLR168C possibly involved in intramitochondrial sorting
similar to uniprot|Q6B217 Saccharomyces cerevisiae YLR246W ERF2 Subunit of a palmitoyltransferase composed of Erf2p and Shr5p that adds a palmitoyl lipid moiety to Ras2p through a thioester linkage mutants partially mislocalize Ras2p to the vacuole
weakly similar to uniprot|Q04007 Saccharomyces cerevisiae YDR186C Hypothetical ORF
similar to uniprot|Q06549 Saccharomyces cerevisiae YLR245C CDD1 Cytidine deaminase catalyzes the modification of cytidine to uridine in vitro but native RNA substrates have not been identified localizes to both the nucleus and cytoplasm
highly similar to uniprot|Q01662 Saccharomyces cerevisiae YLR244C MAP1 Methionine aminopeptidase catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides function is partially redundant with that of Map2p
highly similar to uniprot|P39079 Saccharomyces cerevisiae YDR188W CCT6 Subunit of the cytosolic chaperonin Cct ring complex related to Tcp1p essential protein that is required for the assembly of actin and tubulins in vivo contains an ATP-binding motif
similar to uniprot|P22213 Saccharomyces cerevisiae YDR189W SLY1 Hydrophilic protein involved in vesicle trafficking between the ER and Golgi SM (Sec1/Munc-18) family protein that binds the tSNARE Sed5p and stimulates its assembly into a trans-SNARE membrane-protein complex
highly similar to uniprot|Q03940 Saccharomyces cerevisiae YDR190C RVB1 RUVB-like protein TIP49a Homologue
similar to uniprot|P53688 Saccharomyces cerevisiae YDR191W HST4 Member of the Sir2 family of NAD()-dependent protein deacetylases involved along with Hst3p in silencing at telomeres cell cycle progression radiation resistance genomic stability and short-chain fatty acid metabolism
highly similar to uniprot|Q06543 Saccharomyces cerevisiae YLR243W Protein required for cell viability
similar to uniprot|Q2VQX3 Saccharomyces cerevisiae YLR242C
similar to uniprot|Q06538 Saccharomyces cerevisiae YLR241W Hypothetical ORF
similar to uniprot|P22543 Saccharomyces cerevisiae YLR240W VPS34 Phosphatidylinositol 3-kinase responsible for the synthesis of phosphatidylinositol 3-phosphate; forms membrane-associated signal transduction complex with Vps15p to regulate protein sorting; similar to p110 subunit of mammalian PI 3-kinase
similar to uniprot|P15424 Saccharomyces cerevisiae YDR194C MSS116 DEAD-box protein required for efficient splicing of mitochondrial Group I and II introns presumed RNA helicase due to DEAD-box motif
similar to uniprot|P42073 Saccharomyces cerevisiae YDR195W REF2 RNA-binding protein involved in the cleavage step of mRNA 3'-end formation prior to polyadenylation also involved in snoRNA maturation
similar to uniprot|Q03941 Saccharomyces cerevisiae YDR196C predicted to catalyze the final step in synthesis of Coenzyme A
similar to uniprot|P14905 Saccharomyces cerevisiae YDR197W CBS2 Translational activator of COB mRNA soluble protein cytochrome b translational activator
similar to uniprot|Q03942 Saccharomyces cerevisiae YDR198C Hypothetical ORF
uniprot|O13476 Kluyveromyces lactis KLLA0D18777g LIPB Lipoate-protein ligase, mitochondrial precursor
similar to uniprot|Q03944 Saccharomyces cerevisiae YDR200C VPS64
similar to uniprot|Q03954 Saccharomyces cerevisiae YDR201W SPC19 Component of Dam1p complex important for spindle and kinetochore integrity localized to nuclear side of spindle pole body and along mitotic spindle
similar to uniprot|Q03956 Saccharomyces cerevisiae YDR202C RAV2 Subunit of RAVE (Rav1p Rav2p Skp1p) a complex that associates with the V1 domain of the vacuolar membrane (H)-ATPase (V-ATPase) and promotes assembly and reassembly of the holoenzyme
similar to uniprot|O13525 Saccharomyces cerevisiae YDR204W COQ4 Protein with a role in ubiquinone (Coenzyme Q) biosynthesis possibly functioning in stabilization of Coq7p located on the matrix face of the mitochondrial inner membrane
similar to uniprot|P40164 Saccharomyces cerevisiae YNL201C PSY2 Nuclear protein of unknown function deletion results in sensitivity to anticancer drugs oxaliplatin and cisplatin but not mitomycin C deletion is synthetically lethal with a chitin synthase (CHS1) null mutant
similar to uniprot|P32573 Saccharomyces cerevisiae YNL202W SPS19 late sporulation specific gene which may function during spore wall formation peroxisomal 2 4-dienoyl-CoA reductase
similar to uniprot|P35197 Saccharomyces cerevisiae YDL226C GCS1 ADP-ribosylation factor GTPase activating protein
weakly similar to uniprot|Q05521 Saccharomyces cerevisiae YDR284C DPP1 diacylglycerol pyrophosphate phosphatase
similar to uniprot|P40161 Saccharomyces cerevisiae YNL206C RTT106 Regulator of Ty1 Transposition - same phenotype as RTT101 - RTT105 disruption causes increase in Ty1 transposition. Isolated from the same screen as the other named RTT genes.
highly similar to uniprot|P40160 YNL207W Saccharomyces cerevisiae RIO2 Protein required for cell viability
highly similar to uniprot|P40150 Saccharomyces cerevisiae YNL209W SSB2 Ribosome-associated molecular chaperone heat shock protein of HSP70 family proposed to be involved in the folding of newly synthesized polypeptide chains homolog of SSB1
weakly similar to uniprot|P16523 Saccharomyces cerevisiae YNL210W MER1 Protein with RNA-binding motifs required for meiosis- specific mRNA splicing; required for chromosome pairing and meiotic recombination
similar to uniprot|Q07660 Saccharomyces cerevisiae YDL231C BRE4 Zinc finger protein containing five transmembrane domains null mutant exhibits strongly fragmented vacuoles and sensitivity to brefeldin A a drug which is known to affect intracellular transport
highly similar to uniprot|Q99380 Saccharomyces cerevisiae YDL232W OST4 Subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins; type I membrane protein of 36 residues that binds Stt3p and Ost3p together in a subcomplex
similar to uniprot|P53869 Saccharomyces cerevisiae YNL211C Hypothetical ORF
some similarities with uniprot|P40157 Saccharomyces cerevisiae YNL212W VID27 Vacuole import and degradation
similar to uniprot|P40156 Saccharomyces cerevisiae YNL213C Hypothetical ORF
similar to uniprot|P40155 Saccharomyces cerevisiae YNL214W PEX17 Peroxisomal membrane protein component of the peroxisomal translocation machinery required for peroxisome biogenesis binds Pex14p
weakly similar to uniprot|Q07684 Saccharomyces cerevisiae YDL233W Hypothetical ORF
weakly similar to uniprot|P40154 Saccharomyces cerevisiae YNL215W IES2 Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions
similar to uniprot|P48365 Saccharomyces cerevisiae YDL234C GYP7 GTPase-activating protein for yeast Rab family members including: Ypt7p (most effective) Ypt1p Ypt31p and Ypt32p (in vitro) involved in vesicle mediated protein trafficking
uniprot|Q01073 Kluyveromyces lactis KLLA0D19294g RAP1 DNA-binding protein
similar to uniprot|P40152 Saccharomyces cerevisiae YNL217W Hypothetical ORF
similar to uniprot|Q07688 Saccharomyces cerevisiae YDL235C YPD1 Phosphorelay intermediate protein phosphorylated by the plasma membrane sensor Sln1p in response to osmotic stress and then in turn phosphorylates the response regulators Ssk1p in the cytosol and Skn7p in the nucleus
similar to uniprot|P40151 Saccharomyces cerevisiae YNL218W MGS1 Protein with DNA-dependent ATPase and ssDNA annealing activities involved in maintenance of genome interacts functionally with DNA polymerase delta homolog of human Werner helicase interacting protein (WHIP)
similar to uniprot|P19881 Saccharomyces cerevisiae YDL236W PHO13 Alkaline phosphatase specific for p-nitrophenyl phosphate involved in dephosphorylation of histone II-A and casein
similar to uniprot|P53868 Saccharomyces cerevisiae YNL219C ALG9 catalyzes the transfer of mannose from Dol-P-Man to lipid-linked oligosaccharides mannosyltransferase
highly similar to uniprot|P80210 Saccharomyces cerevisiae YNL220W ADE12 Adenylosuccinate synthase catalyzes the first committed step in the 'de novo' biosynthesis of adenosine
similar to uniprot|P41812 Saccharomyces cerevisiae YNL221C POP1 Subunit of both RNase MRP which cleaves pre-rRNA and nuclear RNase P which cleaves tRNA precursors to generate mature 5' ends binds to the RPR1 RNA subunit in Rnase P
weakly similar to uniprot|Q6B312 Saccharomyces cerevisiae YDL237W Hypothetical ORF
similar to uniprot|Q07729 Saccharomyces cerevisiae YDL238C GUD1 Guanine deaminase a catabolic enzyme of the guanine salvage pathway producing xanthine and ammonia from guanine activity is low in exponentially-growing cultures but expression is increased in post-diauxic and stationary-phase cultures
similar to uniprot|P53538 Saccharomyces cerevisiae YNL222W SSU72 Transcription/RNA-processing factor that associates with TFIIB and cleavage/polyadenylation factor Pta1p exhibits intrinsic phosphatase activity affects start site selection in vivo Nuclear zinc-finger motif containing protein.
similar to uniprot|P53867 Saccharomyces cerevisiae YNL223W ATG4 Cysteine protease required for autophagy cleaves Atg8p to a form required for autophagosome and Cvt vesicle generation mediates attachment of autophagosomes to microtubules through interactions with Tub1p and Tub2p
similar to uniprot|P53866 Saccharomyces cerevisiae YNL224C Hypothetical ORF
weakly similar to uniprot|Q07732 Saccharomyces cerevisiae YDL239C ADY3 Protein required for spore wall formation thought to mediate assembly of a Don1p-containing structure at the leading edge of the prospore membrane via interaction with spindle pole body components potentially phosphorylated by Cdc28p
similar to uniprot|P53863 Saccharomyces cerevisiae YNL227C JJJ1 Protein that may function as a cochaperone as suggested by the presence of a DnaJ-like domain
uniprot|Q96X43 Kluyveromyces lactis Ure2p
weakly similar to uniprot|P53861 Saccharomyces cerevisiae YNL230C ELA1 Elongin A F-box protein that forms a heterodimer with Elc1p and participates in transcription elongation
similar to uniprot|P53859 Saccharomyces cerevisiae YNL232W CSL4 Subunit of the exosome which is an essential complex present in both nucleus and cytoplasm that mediates RNA processing and degradation
similar to uniprot|P53858 Saccharomyces cerevisiae YNL233W BNI4 Targeting subunit for Glc7p protein phosphatase localized to the bud neck required for localization of chitin synthase III to the bud neck via interaction with the chitin synthase III regulatory subunit Skt5p
similar to uniprot|Q75E71 Ashbya gossypii ABL201W ABL201Wp and some similarites with YNL234W uniprot|P53857 Saccharomyces cerevisiae YNL234W Similar to globins and has a functional heme-binding domain involved in glucose signaling or metabolism regulated by Rgt1p
similar to uniprot|P32259 YNL236W Saccharomyces cerevisiae SIN4 involved in positive and negative regulation of transcription
similar to uniprot|P53584 Saccharomyces cerevisiae YNL237W
uniprot|P09231 Kluyveromyces lactis KLLA0D19811g KEX1 protease precursor
uniprot|P53998 Kluyveromyces lactis LET1 PROTEIN
uniprot|P48828 Kluyveromyces lactis G6PD ZWF Glucose-6- phosphate 1-dehydrogenase
similar to uniprot|P35688 Saccharomyces cerevisiae YDL240W LRG1 Putative GTPase-activating protein (GAP) involved in the Pkc1p-mediated signaling pathway that controls cell wall integrity appears to specifically regulate 1 3-beta-glucan synthesis
similar to uniprot|P53855 YNL242W Saccharomyces cerevisiae ATG2 Peripheral membrane protein required for the formation of cytosolic sequestering vesicles involved in vacuolar import through both the Cvt pathway and autophagy
similar to uniprot|Q12512 Saccharomyces cerevisiae YOL154W ZPS1 Putative GPI-anchored protein transcription is induced under low-zinc conditions as mediated by the Zap1p transcription factor and at alkaline pH
weakly similar to uniprot|P35497 Saccharomyces cerevisiae YJR159W SOR1 Sorbitol dehydrogenase
weakly similar to uniprot|Q05016 Saccharomyces cerevisiae YMR226C NADP(+)-dependent dehydrogenase
similar to uniprot|P36172 Saccharomyces cerevisiae YKR105C Hypothetical ORF
similar to uniprot|P36173 Saccharomyces cerevisiae YKR106W
similar to uniprot|P53048 Saccharomyces cerevisiae YGR289C MAL11 Maltose permease inducible high-affinity maltose transporter (alpha-glucoside transporter) encoded in the MAL1 complex locus member of the 12 transmembrane domain superfamily of sugar transporters
some similarities with uniprot|Q08295 Saccharomyces cerevisiae YOL157C Hypothetical ORF