Mixta hanseatica isolate X22927 plasmid pX22927_1, complete sequence.
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Erwiniaceae; Mixta.
First case of bloodstream infection caused by Mixta hanseatica sp. nov., a novel species within the Mixta genus of the Erwiniaceae family
New Microbes New Infect 53, 101117 (2023)
Submitted (02-SEP-2021) Institute of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Martinistr. 52, Hamburg, Hamburg 20246, Germany
REFSEQ INFORMATION: The reference sequence is identical to\nCP082905.1.\nBacteria and source DNA available from Labor Dr. Fenner und\nKollegen, Bergstrasse 14, Hamburg, Germany.\nThe annotation was added by the NCBI Prokaryotic Genome Annotation\nPipeline (PGAP). Information about PGAP can be found here:\nhttps://www.ncbi.nlm.nih.gov/genome/annotation_prok/\n\n##Genome-Assembly-Data-START##\nAssembly Date :: 2021\nAssembly Method :: Unicycler v. 0.4.9\nGenome Representation :: Full\nExpected Final Version :: Yes\nGenome Coverage :: 105.0x\nSequencing Technology :: Illumina NextSeq\n##Genome-Assembly-Data-END##\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: NCBI RefSeq\nAnnotation Date :: 06/25/2023 10:18:00\nAnnotation Pipeline :: NCBI Prokaryotic Genome\n Annotation Pipeline (PGAP)\nAnnotation Method :: Best-placed reference protein\n set; GeneMarkS-2+\nAnnotation Software revision :: 6.5\nFeatures Annotated :: Gene; CDS; rRNA; tRNA; ncRNA\nGenes (total) :: 4,227\nCDSs (total) :: 4,114\nGenes (coding) :: 4,032\nCDSs (with protein) :: 4,032\nGenes (RNA) :: 113\nrRNAs :: 8, 7, 7 (5S, 16S, 23S)\ncomplete rRNAs :: 8, 7, 7 (5S, 16S, 23S)\ntRNAs :: 84\nncRNAs :: 7\nPseudo Genes (total) :: 82\nCDSs (without protein) :: 82\nPseudo Genes (ambiguous residues) :: 0 of 82\nPseudo Genes (frameshifted) :: 19 of 82\nPseudo Genes (incomplete) :: 53 of 82\nPseudo Genes (internal stop) :: 22 of 82\nPseudo Genes (multiple problems) :: 12 of 82\nPseudo Genes (short protein) :: 1 of 82\n##Genome-Annotation-Data-END##\nCOMPLETENESS: full length.
COORDINATES: similar to AA sequence:RefSeq:WP_143212653.1
Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_001288433.1
COORDINATES: ab initio prediction:GeneMarkS-2+
Derived by automated computational analysis using gene prediction method: GeneMarkS-2+.
COORDINATES: protein motif:HMM:NF018044.2
conjugation system SOS inhibitor PsiB family protein
COORDINATES: similar to AA sequence:RefSeq:WP_000194654.1
COORDINATES: similar to AA sequence:RefSeq:WP_000168322.1
COORDINATES: similar to AA sequence:RefSeq:WP_009093276.1
translesion error-prone DNA polymerase V autoproteolytic subunit
COORDINATES: similar to AA sequence:RefSeq:WP_001744069.1
incomplete; partial in the middle of a contig; missing C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_007749371.1
GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]
GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]
metalloregulator ArsR/SmtB family transcription factor
COORDINATES: similar to AA sequence:RefSeq:WP_001549887.1
GO:0005886 - plasma membrane [Evidence IEA]
GO:0015105 - arsenite transmembrane transporter activity [Evidence IEA]
GO:0046685 - response to arsenic-containing substance [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_014606052.1
GO:0008794 - arsenate reductase (glutaredoxin) activity [Evidence IEA]
glutaredoxin-dependent arsenate reductase
COORDINATES: similar to AA sequence:RefSeq:WP_008783811.1
GO:0003674 - molecular_function [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007749362.1
helix-turn-helix domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_014606055.1
GO:0022857 - transmembrane transporter activity [Evidence IEA]
GO:0055085 - transmembrane transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_019106256.1
COORDINATES: similar to AA sequence:RefSeq:WP_019106257.1
COORDINATES: similar to AA sequence:RefSeq:WP_004150760.1
binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; incomplete; partial in the middle of a contig; missing N-terminus and C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_006785986.1
GO:0015074 - DNA integration [Evidence IEA]; GO:0006310 - DNA recombination [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_006785987.1
COORDINATES: similar to AA sequence:RefSeq:WP_007708050.1
COORDINATES: similar to AA sequence:RefSeq:WP_007708053.1
GO:0000155 - phosphorelay sensor kinase activity [Evidence IEA]; GO:0004673 - protein histidine kinase activity [Evidence IEA]; GO:0016772 - transferase activity, transferring phosphorus-containing groups [Evidence IEA]
GO:0000160 - phosphorelay signal transduction system [Evidence IEA]; GO:0016310 - phosphorylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020239536.1
heavy metal response regulator transcription factor
COORDINATES: similar to AA sequence:RefSeq:WP_004098940.1
GO:0006825 - copper ion transport [Evidence IEA]
copper homeostasis membrane protein CopD
COORDINATES: similar to AA sequence:RefSeq:WP_007708063.1
GO:0042597 - periplasmic space [Evidence IEA]
GO:0005507 - copper ion binding [Evidence IEA]
copper homeostasis periplasmic binding protein CopC
COORDINATES: similar to AA sequence:RefSeq:WP_007955870.1
COORDINATES: similar to AA sequence:RefSeq:WP_001176305.1
GO:0005507 - copper ion binding [Evidence IEA]; GO:0005375 - copper ion transmembrane transporter activity [Evidence IEA]
copper resistance system multicopper oxidase
COORDINATES: similar to AA sequence:RefSeq:WP_001183767.1
four-helix bundle copper-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_020314652.1
GO:0003684 - damaged DNA binding [Evidence IEA]
incomplete; partial in the middle of a contig; missing N-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
translesion error-prone DNA polymerase V subunit UmuC
COORDINATES: similar to AA sequence:RefSeq:WP_001297831.1
plasmid partitioning/stability family protein
COORDINATES: similar to AA sequence:RefSeq:WP_001401593.1
GO:0000166 - nucleotide binding [Evidence IEA]
GO:0030541 - plasmid partitioning [Evidence IEA]
COORDINATES: protein motif:HMM:NF033894.1
COORDINATES: similar to AA sequence:RefSeq:WP_001685222.1
COORDINATES: similar to AA sequence:RefSeq:WP_008103203.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0000150 - DNA strand exchange activity [Evidence IEA]
GO:0006310 - DNA recombination [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:YP_005226526.1
GO:0001216 - DNA-binding transcription activator activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:YP_005226527.1
GO:0016787 - hydrolase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010671918.1
glutathione-independent formaldehyde dehydrogenase
COORDINATES: similar to AA sequence:RefSeq:WP_076611469.1
GO:0004803 - transposase activity [Evidence IEA]
programmed frameshift; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: nucleotide motif:Rfam:14.4:RF01497
AL1L pseudoknot; Derived by automated computational analysis using gene prediction method: cmsearch.
COORDINATES: similar to AA sequence:RefSeq:WP_009639360.1
COORDINATES: similar to AA sequence:RefSeq:NP_308438.1
GO:0004024 - alcohol dehydrogenase activity, zinc-dependent [Evidence IEA]; GO:0051903 - S-(hydroxymethyl)glutathione dehydrogenase activity [Evidence IEA]
GO:0006113 - fermentation [Evidence IEA]; GO:0009404 - toxin metabolic process [Evidence IEA]
S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase
COORDINATES: similar to AA sequence:RefSeq:NP_414891.4
formaldehyde-responsive transcriptional repressor FrmR
COORDINATES: similar to AA sequence:RefSeq:WP_012554222.1
zinc-binding alcohol dehydrogenase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_011846847.1
GO:0006313 - DNA transposition [Evidence IEA]
COORDINATES: protein motif:HMM:NF018381.2
COORDINATES: similar to AA sequence:RefSeq:WP_014606784.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0003887 - DNA-directed DNA polymerase activity [Evidence IEA]
GO:0006260 - DNA replication [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004210308.1
COORDINATES: similar to AA sequence:RefSeq:WP_000840441.1
COORDINATES: protein motif:HMM:TIGR03475.1
GO:0006276 - plasmid maintenance [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_000083819.1
COORDINATES: similar to AA sequence:RefSeq:WP_020804818.1
COORDINATES: protein motif:HMM:TIGR02759.1
type IV conjugative transfer system coupling protein TraD
COORDINATES: protein motif:HMM:NF040300.1
COORDINATES: protein motif:HMM:NF010295.2
conjugal transfer mating-pair stabilization protein TraG
COORDINATES: protein motif:HMM:NF017892.2
COORDINATES: protein motif:HMM:TIGR02738.1
type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB
COORDINATES: similar to AA sequence:RefSeq:WP_020802380.1
type-F conjugative transfer system pilin assembly protein TraF
COORDINATES: protein motif:HMM:TIGR02750.1
type-F conjugative transfer system mating-pair stabilization protein TraN
COORDINATES: similar to AA sequence:RefSeq:WP_020802381.1
type-F conjugative transfer system pilin assembly protein TrbC
COORDINATES: similar to AA sequence:RefSeq:WP_016529742.1
conjugal transfer pilus assembly protein TraU
COORDINATES: similar to AA sequence:RefSeq:WP_009638853.1
COORDINATES: protein motif:HMM:TIGR02743.1
type-F conjugative transfer system protein TraW
COORDINATES: protein motif:HMM:NF021213.2
COORDINATES: protein motif:HMM:TIGR02746.1
COORDINATES: protein motif:HMM:TIGR02747.1
type IV conjugative transfer system lipoprotein TraV
COORDINATES: protein motif:HMM:NF015688.2
COORDINATES: protein motif:HMM:NF018311.2
type-F conjugative transfer system secretin TraK
COORDINATES: protein motif:HMM:NF017152.2
TraE/TraK family type IV conjugative transfer system protein
COORDINATES: protein motif:HMM:TIGR02762.1
type IV conjugative transfer system protein TraL
COORDINATES: protein motif:HMM:NF017337.2
GO:0005576 - extracellular region [Evidence IEA]
type IV conjugative transfer system pilin TraA
COORDINATES: similar to AA sequence:RefSeq:WP_004966240.1
lytic transglycosylase domain-containing protein
COORDINATES: protein motif:HMM:NF037428.2
COORDINATES: similar to AA sequence:RefSeq:WP_020230320.1
COORDINATES: similar to AA sequence:RefSeq:WP_009654279.1
COORDINATES: similar to AA sequence:RefSeq:WP_013199995.1
COORDINATES: protein motif:HMM:NF014273.2
ParB/RepB/Spo0J family partition protein
COORDINATES: similar to AA sequence:RefSeq:WP_004152756.1
GO:0008168 - methyltransferase activity [Evidence IEA]; GO:1904047 - S-adenosyl-L-methionine binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_009093298.1