Encephalitozoon cuniculi GB-M1 chromosome XI, complete sequence.
Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Unikaryonidae; Encephalitozoon.
Identification of transcriptional signals in Encephalitozoon cuniculi widespread among Microsporidia phylum: support for accurate structural genome annotation
Genome sequence and gene compaction of the eukaryote parasite Encephalitozoon cuniculi
Transcriptional signals for accurate microsporidian genome annotation, supporting high quality comparative genomics
Submitted (22-DEC-2022) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (30-AUG-2000) Genoscope -Centre National de Sequencage, 2 rue Gaston Cremieux, CP 5706, 91057 EVRY cedex, FRANCE. (E-mail : seqref@genoscope.cns.fr - Web : www.genoscope.cns.fr)
PROVISIONAL REFSEQ: This record has not yet been subject to final\nNCBI review. The reference sequence is identical to AL590450.\n\nOn Dec 22, 2022 this sequence version replaced NC_003237.1.\nCorresponding author : Equipe de Parasitologie Moleculaire et\nCellulaire, UMR CNRS 6023, Universite Blaise Pascal, 63177 Aubiere\ncedex, France E-mail : Christian.VIVARES@lbp.univ-bpclermont.fr Tel\n: (33) (0)4.73.40.74.57 Fax : (33) (0)4.73.40.74.55 Web :\nhttp://www.protistes.univ-bpclermont.fr/fr/parasito.htm The\nsubmitted sequence encompasses the coding core of the chromosome.\nThe telomeric and subtelomeric sequences are not included in this\nsubmission.\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: INSDC submitter\nAnnotation Status :: Full annotation\nAnnotation Pipeline :: Eukaryotic Annotation Propagation Pipeline\n##Genome-Annotation-Data-END##
11_0120, unknown, gene found by Glimmer [Bad Olap 11 521 0]
11_0140, DNA 3-METHYLADENINE GLYCOSYLASE, 3MGH_BACSU, gene found by Glimmer
11_0150, unknown, gene found by Glimmer [Shorter 16 413 99]
11_0170, LEUCINE-RICH RAS SUPPRESSOR PROTEIN, RSU1_HUMAN, gene found by Glimmer [Shorter 16 327 99]
11_0180, SER/THR PROTEIN KINASE (MNB/DYRK SUBFAMILY), YAK1_yeast, gene found by Glimmer
11_0190, TRANSCRIPTIONAL REGULATOR-LIKE PROTEIN, SIN3_yeast, gene found by Glimmer
11_0220, TRANSCRIPTION FACTOR TFIIH, Tfb SUBUNIT (similar to mammalian CAK subunit), MAT1_HUMAN, gene found by Glimmer
11_0230, TRIOSE PHOSPHATE ISOMERASE, TPIS_SCHJA, gene found by Glimmer
11_0240, EXPORTIN 1 (NUCLEAR EXPORT FACTOR), CRM1_SCHPO, CRM1_yeast, gene found by Glimmer
11_0300, similarity to HYPOTHETICAL PROTEINS(UPF 0038 family) YACE_BRELA and YD96_yeast, gene found by Glimmer
11_0330, some similarity to ribonucleoside diphosphate reductase (alpha chain), gene found by Glimmer
11_0340, LIM DOMAIN-CONTAINING PROTEIN, SLI3_MOUSE, gene found by Glimmer
11_0350, RAB GDP DISSOCIATION INHIBITOR, GDI1_yeast, gene found by Glimmer
11_0360, similarity to SUPPRESSOR OF THE TEMPERATURE-SENSITIVE GROWTH OF YEAST MRP1 MUTANTS, SOH1_yeast, gene found by Glimmer
11_0370, DNA-DIRECTED RNA POLYMERASE III SUBUNIT 2 (130kDa SUBUNIT), RPC2_SCHPO, gene found by Glimmer
tRNA found by tRNAscan-SE, tRNA type: Leu, Anticodon: TAG, Score: 59.63
11_0400, similarity to HYPOTHETICAL PROTEIN YHY1_yeast, v6.12,gene found by Glimmer
tRNA found by tRNAscan-SE, tRNA type: Met, Anticodon: CAT, Score : 69.52
11_0430, similarity to SKT5 PROTEIN (INTERACTS WITH SEPTINS), YAIA_SCHPO, SKT5_yeast, gene found by Glimmer
11_0450, PHOSPHATIDYLINOSITOL 4-KINASE (C-terminal region), STT4_yeast, gene found by Glimmer
pescadillo N-terminus domain-containing protein
11_0470, KINESIN-RELATED PROTEIN (possibly involved in mitosis), KIF2_HUMAN, gene found by Glimmer
11_0480, CTP SYNTHASE, PYRG_MOUSE, gene found by Glimmer
11_0500, unknown, gene found by Glimmer [Delay by 552 49 498 0]
11_0510, unclear, some similarity to chitooligosaccharide deacetylase (nodulation protein B), NODB_RHIME, gene found by Glimmer
11_0530, TRYPTOPHANYL tRNA SYNTHETASE, SYW_SCHPO, gene found by Glimmer
11_0540, HSP70-LIKE PROTEIN (MITOCHONDRIAL TYPE), GR75_HUMAN, E. cuniculi gene DNA cross-ref : AJ012470, gene found by Glimmer
11_0550, ZINC FINGER PROTEIN, GLO3_yeast, YIE4_yeast, gene found by Glimmer
11_0560, similarity to HYPOTHETICAL PROTEIN (cornichon family) YB60_Yeast, gene found by Glimmer
proteasome regulatory particle lid subunit RPN11
11_0570, PROTEASOME REGULATORY SUBUNIT 11 (RPN11 family), PAD1_SCHPO, gene found by Glimmer
DNA-directed RNA polymerase core subunit RPC19
11_0590, DNA-DIRECTED RNA POLYMERASE I AND III SUBUNIT 14K (14 kDa polypeptide), RPC9_SCHPO, gene found by Glimmer
11_0610, CLEAVAGE AND POLYADENYLATION SPECIFIC FACTOR, LARGE (160 kDa) SUBUNIT, CPSA_HUMAN, gene found by Glimmer
diacylglycerol ethanolamine phosphotransferase
11_0620, DIACYLGLYCEROL ETHANOLAMINE PHOSPHOTRANSFERASE, EPT1_yeast, E. cuniculi gene DNA cross-ref : AJ310089, gene found by Glimmer
11_0640, VESICLE-ASSOCIATED MEMBRANE PROTEIN, VAMP_MOUSE, gene found by Glimmer
mRNA-binding translational activator GIS2
11_0650, similarity to DNA-BINDING PROTEIN HEXBP 2 (HEXAMER-BINDING PROTEIN), HEXP_LEIMA, gene found by Glimmer
type 1 serine/threonine-protein phosphatase catalytic subunit GLC7
11_0660, SER/THR PROTEIN PHOSPHATASE PPI-1 CATALYTIC SUBUNIT, YME1_CAEEL, PPI1_SCHPO, gene found by Glimmer
11_0670, similarity to HYPOTHETICAL PROTEIN YG22_yeast, gene found by Glimmer
11_0690, MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE, MPG1_yeast, gene found by Glimmer
11_0710, unknown, gene found by Glimmer [Bad Olap 76 68 0]
11_0720, 40S RIBOSOMAL PROTEIN S20, RS20_ORYSA, gene found by Glimmer [Shorter 75 68 99]
11_0730, TATA-BINDING PROTEIN-ASSOCIATED PHOSPHOPROTEIN, TBAP_HUMAN, gene found by Glimmer
11_0750, similarity to HYPOTHETICAL PROTEIN Y443_METJA, gene found by Glimmer
11_0760, EXONUCLEASE 1, EXO1_SCHPO, gene found by Glimmer
11_0770, similarity to CARBON CATABOLITE REPRESSOR PROTEIN 4 (transcriptional effector CCR4), CCR4_yeast, gene found by Glimmer
11_0780, 40S RIBOSOMAL PROTEIN S7, RS7_SCHPO, gene found by Glimmer
11_0790, PROTEIN TRANSPORT PROTEIN SEC23 HOMOLOG (COPII COAT), S23B_HUMAN, SC23_yeast, gene found by Glimmer
11_0800, DNA REPLICATION LICENSING FACTOR MCM4, MCM4_DROME, gene found by Glimmer
11_0810, similarity to HYPOTHETICAL PROTEIN: YEV6_yeast, gene found by Glimmer
11_0820, DNA REPAIR PROTEIN RAD51 HOMOLOG, RA51_CHICK, gene found by Glimmer
11_0830, similarity to TRANSCRIPTION INITIATION FACTOR TFIID 30kDa SUBUNIT, T2D8_HUMAN, T2D8_yeast, gene found by Glimmer
11_0840, PROTEASOME REGULATORY SUBUNIT YTA6 OF THE AAA FAMILY OF ATPASES, TBP6_yeast, SKD1_SCHPO, gene found by Glimmer
11_0850, CDP DIACYLGLYCEROL SERINE O-PHOSPHATIDYLTRANSFERASE, PEL1_yeast, gene found by Glimmer, CDS fused by annotation, 2 introns created
11_0860, possible PRE-mRNA SPLICING FACTOR (ATP-DEPENDENT RNA HELICASE), DDX8_SCHPO, PRH1_SCHPO, PR22_yeast, gene found by Glimmer
ethanolamine-phosphate cytidylyltransferase
11_0870, U5 ASSOCIATED snRNP, MUQ1_yeast, gene found by Glimmer
11_0880, CTP SYNTHASE, PYRG_yeast, gene found by Glimmer
11_0890, METHIONYL tRNA SYNTHETASE, SYM_CAEEL, gene found by Glimmer
11_0900, similarity to HYPOTHETICAL PROTEINS YM8P_yeast and YAV9_SCHPO, gene found by Glimmer
11_0920, unknown, gene found by Glimmer [Shorter 100 149 99]
translation initiation factor eIF2 subunit alpha
11_0930i, TRANSLATION INITIATION FACTOR 2 ALPHA SUBUNIT (eIF2 alpha), IF2A_METJA, gene found by Glimmer, [Bad Olap 99 149 0], modified ATG by annotation
11_0940, HIGH MOBILITY GROUP-LIKE NUCLEAR PROTEIN (HMG2), NHP2_yeast, NHPX_CAEEL, gene found by Glimmer [Delay by 558 102 492 0]
11_0960, CELL DIVISION CONTROL PROTEIN 2 HOMOLOG (CDC2-LIKE CELL CYCLE PROTEIN KINASE), CC2A_ANTMA, gene found by Glimmer
11_0970, unknown, gene found by Glimmer [Delay by 267 103 222 0]
11_0980, SYNAPTOBREVIN-RELATED PROTEIN, SYBR_ARATH, gene found by Glimmer
11_0990, ZINC FINGER PROTEIN, ZG3_XENLA, ZG46_XENLA, gene found by Glimmer
11_1030, PROTEASOME REGULATORY SUBUNIT YTA6 OF THE AAA FAMILY OF ATPASES, TBP6_yeast, SAP1_yeast, gene found by Glimmer
11_1050, OLIGOPEPTIDE TRANSPORTER (PTR2 family of transporters), OPT1_DROME, gene found by Glimmer
11_1070, similarity to HYPOTHETICAL OXIDOREDUCTASE (SHORT CHAIN DEHYDROGENASE/REDUCTASE FAMILY) YAEB_SCHPO, gene found by Glimmer
11_1080, MANGANESE SUPEROXIDE DISMUTASE, SODM_BACCA, gene found by Glimmer
11_1100, ISOLEUCYL tRNA SYNTHETASE, SYI_HUMAN, gene found by Glimmer
11_1120, TRANSLATION ELONGATION FACTOR 2 (EF2), EF2_METTH, gene found by Glimmer
11_1130, similarity to HYPOTHETICAL ZINC FINGER PROTEIN (C3HC4 class) YQ57_CAEEL, gene found by Glimmer [Delay by 312 122 329 0]
11_1150, similarity to MEMBRANE PROTEIN ORM1, ORM1_yeast, gene found by Glimmer
11_1160, POSSIBLE PROTEIN OF NUCLEAR SCAFFOLD, BIMA_EMENI, gene found by Glimmer
11_1170, similarity to HYPOTHETICAL WD-REPEAT PROTEIN (5 WD repeats) YMY3_yeast, gene found by Glimmer
11_1180, PHOSPHOLIPASE D, PLD2_RAT, gene found by Glimmer
11_1190, NBP35-LIKE NUCLEOTIDE BINDING PROTEIN, NB35_yeast, gene found by Glimmer
11_1200, ABC TRANSPORTER (mitochondrial type), ABC7_HUMAN, ATM1_yeast, HMT1_SCHPO, gene found by Glimmer
11_1230, similarity to HYPOTHETICAL PROTEIN YDD5_SCHPO, gene found by Glimmer
tRNA found by tRNAscan-SE, tRNA type: Gly, Anticodon: CCC, Score: 67.83
11_1260, DNA MISMATCH REPAIR PROTEIN OF THE MUTL/HEXB FAMILY, HEXB_STRPN, MUTL_BACSU, PMS2_HUMAN, gene found by Glimmer
RuvB family ATP-dependent DNA helicase reptin
11_1270, similarity to HYPOTHETICAL PROTEIN YP59_MYCTU, gene found by Glimmer
11_1280i, VACUOLAR ATP SYNTHASE CATALYTIC SUBUNIT A (67 kDa), VATA_SCHPO, gene found by Glimmer, modified ATG by annotation
11_1290, CELL CYCLE PROTEIN KINASE OF THE CDC2/CDKX FAMILY, CDKA_HUMAN, gene found by Glimmer
11_1310, NADPH ADRENODOXIN OXIDOREDUCTASE, ADRO_yeast, gene found by Glimmer
11_1320, similarity to PLASMODIUM MEMBRANE PROTEIN (PLASMODIUM ANTIGEN A412), A412_PLAFA, gene found by Glimmer
11_1330, TRANSCRIPTION FACTOR (forkhead domain), FXJ1_HUMAN, gene found by Glimmer
11_1340, ABC TRANSPORTER-LIKE PROTEIN, PDRF_yeast, gene found by Glimmer
11_1350, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, IFE4_CAEEL, IF4E_APLCA, gene found by Glimmer
11_1360, similarity to CELL APOPTOSIS-RELATED GENE TFAR19, TF19_HUMAN, gene found by Glimmer
11_1370, NOT1-LIKE GENERAL NEGATIVE REGULATOR OF TRANSCRIPTION SUBUNIT 1, NOT1_yeast, gene found by Glimmer
11_1380i, 60S RIBOSOMAL PROTEIN L15, RL15_CHITE, gene found by Glimmer, modified ATG by annotation
cleavage polyadenylation factor subunit FIP1
DNA-directed RNA polymerase II core subunit RPB9
11_1400, DNA-DIRECTED RNA POLYMERASE II SUBUNIT 14. 5 kDa, RPB9_HUMAN, RPB9_yeast, gene found by Glimmer
11_1420, HSP 101 RELATED PROTEIN, BELONGS TO THE CLPB PROTEASE FAMILY (induced by heat shock), CLPB_HAEIN, H101_ARATH, gene found by Glimmer
11_1430, DIPHTIN SYNTHASE, DPH5_yeast, gene found by Glimmer
11_1450, PROTEIN TRANSPORT PROTEIN SEC13 HOMOLOG (COPII COAT), SEC13_PICPA, gene found by Glimmer
11_1460, TRANSLATION ELONGATION FACTOR 2 (EF2), EF2_SCHPO, gene found by Glimmer
negative cofactor 2 transcription regulator complex subunit BUR6
11_1470, CLASS 2 TRANSCRIPTIONAL REPRESSOR similar to histones H2A, NCB1_yeast
11_1490, SPLICING FACTOR FOR U2 snRNP BINDING TO PRE-mRNA DURING SPLICEOSOME ASSEMBLY, S145_HUMAN, CUS1_yeast, gene found by Glimmer
11_1500, NIMA-LIKE SER/THR PROTEIN KINASE, NEK3_MOUSE, gene found by Glimmer
11_1510, ZINC TRANSPORTER (endosomes), ZNT4_HUMAN, gene found by Glimmer
11_1520, similarity to HYPOTHETICAL METHYLTRANSFERASE-LIKE PROTEIN YGGH_ECOLI, gene found by Glimmer
11_1540, HEXOKINASE, HXK_SCHMA, gene found by Glimmer
DNA-(apurinic or apyrimidinic site) lyase APN1
11_1550i, DNA LYASE/ENDONUCLEASE 4, APN1_CAEEL, END4_BUCAI, gene found by Glimmer, modified ATG by annotation
11_1560, PROTEIN OF THE SYNTAXIN/EPIMORPHIN FAMILY (SYNTAXIN-RELATED PROTEIN), YJD7_yeast, gene found by Glimmer
11_1570, putative zinc finger protein, gene found by Glimmer
11_1580, similarity to HYPOTHETICAL ABC TRANSPORTER Y719_METJA, gene found by Glimmer
11_1590, SPINDLE POLE BODY ASSOCIATED PROTEIN, SAD1_SCHPO, gene found by Glimmer [Delay by 435 175 340 0]
11_1600, similarity to FOLATE TRANSPORTER, FLO1_CAEEL, gene found by Glimmer
11_1610, tRNA PSEUDOURIDINE SYNTHASE A, TRUA_METTH, TRUA_METTH, gene found by Glimmer
11_1620i, 40S RIBOSOMAL PROTEIN S19, R19E_METJA, gene found by Glimmer, modified ATG by annotation
11_1640, INORGANIC PHOSPHATE TRANSPORTER, PHO88 HOMOLOG, PH88_yeast, gene found by Glimmer
CCR4-NOT core ubiquitin-protein ligase subunit MOT2
11_1660, RING ZINC FINGER TRANSCRIPTION NEGATIVE REGULATOR FACTOR, YAC4_SCHPO, gene found by Glimmer
11_1670, 20S PROTEASOME ALPHA SUBUNIT (C2), PRC2_MOUSE, gene found by Glimmer
11_1690, unclear, some similarity to Myb-related transcription factor (fragment), MYBA_HUMAN, gene found by Glimmer
11_1700, similarity to HYPOTHETICAL TRANSMEMBRANE PROTEIN YADA_SCHPO, gene found by Glimmer
11_1730, RNA-BINDING PROTEIN OF THE PUMILIO FAMILY), YDHE_SCHPO, YAD3_SCHPO, gene found by Glimmer
11_1740, similarity to HYPOTHETICAL AMINOACID TRANSPORTER, YEU9_yeast, YEH4_yeast, gene found by Glimmer
11_1750, TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 72/90-100 kDa, T2D4_yeast, T2D4_SCHPO, T2D4_HUMAN, gene found by Glimmer
11_1760, IMPORTIN ALPHA SUBUNIT (KARYOPHERIN), IMA1_SCHPO, gene found by Glimmer
11_1770, NIFS-LIKE PROTEIN (CYSTEINE DESULFURASE) INVOLVED IN IRON-SULFUR CLUSTER SYNTHESIS, NFS1_CANAL, gene found by Glimmer
11_1780, UDP-N-ACETYLGLUCOSAMINE PYROPHOSPHORYLASE, UAP1_yeast, gene found by Glimmer
11_1790, unclear, some similarity to histones H1 (BlastN prediction only), gene found by Glimmer
bifunctional (2E,6E)-farnesyl diphosphate synthase/dimethylallyltranstransferase
11_1810, FARNESYL PYROPHOSPHATE SYNTHETASE, FPPS_HELAN, gene found by Glimmer
11_1820, NUCLEAR PORE COMPLEX PROTEIN (NUCLEOPORIN NUP116), N116_yeast, gene found by Glimmer
11_1830, DNAK-LIKE PROTEIN (HEAT SHOCK PROTEIN OF THE HSP70 FAMILY), HS70_PLAFA, gene found by Glimmer
11_1870, SUGAR PERMEASE (MALTOSE-RELATED PERMEASE), MALA_BACST, gene found by Glimmer
11_1880, NUCLEOSIDE TRANSPORTER, YEGT_ECOLI, gene found by Glimmer
11_1910, IMP4-LIKE U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN (snoRNP), YEE7_SCHPO, YHPK_CAEEL, IMP4_yeast, gene found by Glimmer
11_1920, ENDOPLASMIC RETICULUM MEMBRANE PROTEIN DEGRADING MISFOLDED ER LUMINAL PROTEINS, DER1_YEAST, gene found by Glimmer
11_1930, unclear, some similarity to putative transcription factor SPT5, SPT5_yeast, gene found by Glimmer
11_1950, SEPTIN HOMOLOG (CDC10 HOMOLOG) C10H_MOUSE, gene found by Glimmer
11_1980, CASEINE KINASE 1, KC1A_BOVIN, gene found by Glimmer
11_1990, UBIQUITIN CONJUGATING ENZYME E2-16kDa, UBC5_yeast, gene found by Glimmer
11_2000, putative NUCLEAR PROTEIN OF THE SMC FAMILY (CHROMOSOME SEGREGATION PROTEIN), YDZ2_SCHPO, gene found by Glimmer
11_2020, KINESIN-LIKE DNA-BINDING PROTEIN, KID_HUMAN, gene found by Glimmer
homeodomain family transcription factor STE12
11_2030, TRANSCRIPTION FACTOR (STE12 HOMOLOG), STE12_CANAL, gene found by Glimmer
11_2060, 60S RIBOSOMAL PROTEIN L35, RL35_SCHPO, gene found by Glimmer
11_2070, Sm-LIKE PROTEIN, U6 snRNA-ASSOCIATED SMALL NUCLEAR RIBONUCLEOPROTEIN (U6 snRNP), RUXX_THEAC
11_2080i, unknown, gene found by Glimmer