Encephalitozoon cuniculi GB-M1 chromosome III, complete sequence.
Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Unikaryonidae; Encephalitozoon.
Identification of transcriptional signals in Encephalitozoon cuniculi widespread among Microsporidia phylum: support for accurate structural genome annotation
Genome sequence and gene compaction of the eukaryote parasite Encephalitozoon cuniculi
Transcriptional signals for accurate microsporidian genome annotation, supporting high quality comparative genomics
Submitted (22-DEC-2022) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (30-AUG-2000) Genoscope -Centre National de Sequencage, 2 rue Gaston Cremieux, CP 5706, 91057 EVRY cedex, FRANCE. (E-mail : seqref@genoscope.cns.fr - Web : www.genoscope.cns.fr)
PROVISIONAL REFSEQ: This record has not yet been subject to final\nNCBI review. The reference sequence is identical to AL590443.\nCorresponding author : Equipe de Parasitologie Moleculaire et\nCellulaire, UMR CNRS 6023, Universite Blaise Pascal, 63177 Aubiere\ncedex, France E-mail : Christian.VIVARES@lbp.univ-bpclermont.fr Tel\n: (33) (0)4.73.40.74.57 Fax : (33) (0)4.73.40.74.55 Web :\nhttp://www.protistes.univ-bpclermont.fr/fr/parasito.htm The\nsubmitted sequence encompasses the coding core of the chromosome.\nThe telomeric and subtelomeric sequences are not included in this\nsubmission.\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: INSDC submitter\nAnnotation Status :: Full annotation\nAnnotation Pipeline :: Eukaryotic Annotation Propagation Pipeline\n##Genome-Annotation-Data-END##
03_0010, unknown, gene found by Glimmer [Bad Olap 2 167 0]
03_0020, unknown, gene found by Glimmer [Shorter 1 167 0]
03_0060, unknown, gene found by Glimmer [Delay by 228 5 109 38]
03_0070, unknown, gene found by Glimmer [Shorter 8 242 99]
03_0080, unknown, gene found by Glimmer [Bad Olap 7 242 0]
03_0100, similarity to HYPOTHETICAL PROTEIN Y461_MYCPN, gene found by Glimmer
03_0150, GOLGI MEMBRANE PROTEIN, GDP-MANNOSE TRANSPORTER, GOG5_yeast gene found by Glimmer
chromatin organization modifier domain-containing protein
03_0180, CHROMOBOX PROTEIN, HETEROCHROMATIN PROTEIN 1, CBX1_HUMAN, gene found by Glimmer
03_0200, similarity to putative DEOXYRIBONUCLEASE OF THE TATD FAMILY, TATD_ECOLI, YBF5_yeast, gene found by Glimmer
03_0210, similarity to HYPOTHETICAL PROTEIN YAAT_BACSU, gene found by Glimmer
03_0220, T COMPLEX PROTEIN 1 ALPHA SUBUNIT, TCPA_yeast, gene found by Glimmer
ribosomal protein L31e domain-containing protein
03_0230, 60S RIBOSOMAL PROTEIN L31, RL31_yeast, gene found by Glimmer
03_0240, ABC TRANSPORTER, Y288_THEMA, HMT1_SCHPO, gene found by Glimmer
03_0250, unclear (some similarity to glucose/Na cotransporter), gene found by Glimmer
03_0270, COATOMER PROTEIN GAMMA SUBUNIT, GAMMA-COAT PROTEIN (GAMMA-COP), COPG_SCHPO, gene found by Glimmer
UTP-glucose-1-phosphate uridylyltransferase
03_0280, UTP GLUCOSE 1 PHOSPHATE URIDYLTRANSFERASE 1, UDPG_yeast, gene found by Glimmer
03_0290, DNA-DIRECTED RNA POLYMERASE II, FIRST LARGEST SUBUNIT, RPB1_SCHPO, gene found by Glimmer
03_0305, VACUOLAR ATP SYNTHASE SUBUNIT F (V-ATPASE 14kDa SUBUNIT), VATF_RAT
03_0310, 40S RIBOSOMAL PROTEIN S16, RS16_LUPPO, gene found by Glimmer
03_0320, 60S RIBOSOMAL PROTEIN L13, RL13_CANAL, gene found by Glimmer
tRNA found by tRNAscan-SE, tRNA type: Ser, Anticodon: TGA, Score: 62.18
03_0330, PHOSPHATIDYLINOSITOL-4-PHOSPHATE-5-KINASE, MSS4_yeast, gene found by Glimmer
03_0340, PHOSPHOMANNO(GLUCO)MUTASE, YM8L_yeast, gene found by Glimmer
tRNA found by tRNAscan-SE, tRNA type: Asp, Anticodon: GTC, Score: 62.99
03_0360, U6 snRNA ASSOCIATED SM-LIKE PROTEIN (GLYCINE-RICH PROTEIN), LSM4-HUMAN
03_0390, ABC TRANSPORTER, PDR5_yeast, gene found by Glimmer
03_0420, similarity to yeast CDC68 (GENERAL TRANSCRIPTION, PASSAGE THROUGH START), CC68_yeast, gene found by Glimmer
03_0430, WD repeats-containing protein, gene found by Glimmer
03_0440, DNA-DIRECTED RNA POLYMERASE I, SECOND LARGEST SUBUNIT, RPA2_yeast, gene found by Glimmer
03_0460, SIR2-LIKE PROTEIN INVOLVED IN TELOMERIC SILENCING (suppresses rDNA recombination and promotes histone deacetylation), HST4_yeast, gene found by Glimmer [Bad Olap 60 159 0]
03_0470, GTP-BINDING ADP RIBOSYLATION FACTOR (ARF), ARFM_CAEEL, gene found by Glimmer [Shorter 61 159 99]
03_0480, SPLICEOSOME-ASSOCIATED PROTEIN 62 (SPLICING FACTOR 3A SUBUNIT 2), SP62_MOUSE, gene found by Glimmer
DNA-directed RNA polymerase III core subunit RPC11
03_0490, DNA-DIRECTED RNA POLYMERASE III 12.5kDa SUBUNIT, RPCZ_yeast, gene found by Glimmer
03_0500, VACUOLAR ATP SYNTHASE SUBUNIT C (V-ATPASE 42kDa SUBUNIT), VATC_yeast, gene found by Glimmer
03_0520,HEAT SHOCK RELATED 70kDa PROTEIN (HSP 70 FAMILY), HS7C_MOUSE, gene found by Glimmer
03_0540, DNA MISMATCH REPAIR PROTEIN (MUTS FAMILY), MSH2_HUMAN, gene found by Glimmer
03_0570, similarity to HYPOTHETICAL PROTEIN YANE_SCHPO, gene found by Glimmer
03_0580, UBIQUITIN CARBOXY-TERMINAL HYDROLASE, UBPB_SCHPO, gene found by Glimmer
03_0590, similarity to HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN YIPA_yeast, gene found by Glimmer
03_0600, unclear, some similarity with homeobox domain-containing protein, HMO8_CAEEL, gene found by Glimmer
03_0610, unclear, homeobox domain, gene found by Glimmer
03_0620, CHK1-LIKE SER/THR PROTEIN KINASE (CHECKPOINT 1), CHK1_SCHPO, gene found by Glimmer, modified ATG by annotation
03_0630, CALMODULIN-DEPENDENT PROTEIN KINASE, BYR2_SCHPO, gene found by Glimmer
03_0650, 40S RIBOSOMAL PROTEIN S14, RS14_SCHPO, gene found by Glimmer
03_0660, UBIQUITIN CARBOXY-TERMINAL HYDROLASE 14 (UBIQUITIN THIOLESTERASE 14, UBIQUITIN-SPECIFIC PROCESSING PROTEASE 14), UBPE_yeast, gene found by Glimmer
ribonuclease H2 catalytic subunit RNH201
03_0670, BELONGS TO THE RIBONUCLEASE HII FAMILY, YNH2_yeast, RNH2_PYRHO, gene found by Glimmer
03_0680, 6-PHOSPHOFRUCTOKINASE (PHOSPHOFRUCTO-1-KINASE ISOENZYME A), K6PF_CANFA, gene found by Glimmer
03_0700, similarity to DIS3 PROTEIN (RNASE II FAMILY, MITOTIC CONTROL), DIS3_yeast,v24.11, gene found by Glimmer; similarity to DIS3 PROTEIN (RNASE II FAMILY)
03_0710, 60S RIBOSOMAL PROTEIN L34, RL34_AEDAL, R34A_yeast, gene found by Glimmer [Shorter 74 132 99]
No homology, frame of 03_0750, gene found by Glimmer [Bad Olap 73 132 0] [Bad Olap 75 223 0], rejected by annotation
No homology, frame of 03_0700, gene found by Glimmer [Shorter 74 223 99], rejected by annotation
03_0730, NUCLEOLAR PROTEIN OF THE GAR FAMILY, (40S assembly), GAR2_SCHPO,gene found by Glimmer [Shorter 78 239 99]
03_0750, U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A (U1snRNP A), RU1A_HUMAN, gene found by Glimmer [Shadowed by 78]
03_0760, similarity to 20kDa NUCLEAR CAP BINDING PROTEIN, CB20_HUMAN, gene found by Glimmer [Shorter 78 130 99]
03_0790, similarity to NUCLEAR ZINC FINGER PROTEIN INVOLVED IN TRANSCRIPTIONAL CONTROL, Z229_HUMAN, gene found by Glimmer
03_0820i, TUBULIN BETA CHAIN, TBB4_XENLA, TBB2_HUMAN, gene found by Glimmer, modified ATG by annotation
03_0840, similarity to SMALL NUCLEAR RIBONUCLEOPROTEIN D3 (snRNP SMD3, REQUIRED FOR VACUOLAR PROTEIN SORTING), SMD3_yeast
03_0880, BIS (5'-NUCLEOSYL) TETRAPHOSPHATASE, APH1_yeast,(init.ATG position?), gene found by Glimmer
03_0890, similarity to DNA DAMAGE-RESPONSE PROTEIN, ALK1_yeast, gene found by Glimmer
03_0900, similarity to putative VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN (SEC1 FAMILY), YAB3_SCHPO, gene found by Glimmer; similarity VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN (SEC1 FAMILY)
03_0910, CASEIN KINASE 1 HOMOLOG (INVOLVED IN DNA REPAIR), HHP2_SCHPO, gene found by Glimmer
03_0920, tRNA-INTRON ENDONUCLEASE, ENDA_METH, gene found by Glimmer
03_0930, UBIQUITIN-ACTIVATING ENZYME E1, UBA1_RABIT, UBA1_yeast gene found by Glimmer
03_0940, zinc finger protein, GL14_XENLA, gene found by Glimmer
03_0950, 60S RIBOSOMAL PROTEIN L7, RL7C_SCHPO, gene found by Glimmer
03_0980, similarity to SER/THR PROTEIN KINASE KIN1 (INVOLVED IN CELL POLARITY AND GROWTH), KIN1_SCHPO, gene found by Glimmer
03_1010, similarity to 14-3-3 PROTEIN 1,(KINASE C INHIBITOR PROTEIN), 143B_RAT, gene found by Glimmer
03_1030, ORIGIN RECOGNITION COMPLEX SUBUNIT 1 (REPLICATION CONTROL PROTEIN 1), ORC1_DROME, gene found by Glimmer
transcription factor TFIIIB subunit BDP1
03_1040, unclear, with some similarity to yeast TFC5 (TFIIIB), gene found by Glimmer [Delay by 48 109 65 0]
03_1070, unclear, with some similarity to transcription initiation factor TFIIA 32kDa subunit, TOA1_yeast, gene found by Glimmer
03_1080, STRUCTURE-SPECIFIC ENDONUCLEASE OF THE XPG/RAD2 FAMILY, FEN1_HUMAN, RAD2_SCHPO, gene found by Glimmer
tRNA found by tRNAscan-SE, tRNA type: Phe, Anticodon: GAA, Score: 73.26
03_1100, PHOSPHATIDYLINOSITOL-4-KINASE CATALYTIC SUBUNIT, PIK1_yeast, gene found by Glimmer
03_1120, V-TYPE SODIUM ATP SYNTHASE SUBUNIT K (SODIUM ATPase PROTEOLIPID COMPONENT), NTPK_ENTAR, gene found by Glimmer
similarity to hypothetical protein YK82_CAEEL
03_1130, with some similarity to hypothetical protein YK82_CAEEL, gene found by Glimmer
03_1150, CALCIUM-BINDING PROTEIN SIMILAR TO CALPONIN H2, MP20_DROME, CLP2_MOUSE, gene found by Glimmer [Shorter 122 521 99]
03_1160, RECESSIVE SUPPRESSOR OF SECRETORY DEFECT (coordination between secretion and actin cytoskeleton), RSD1_yeast, gene found by Glimmer
homeodomain-containing transcription factor
03_1170, similarity to LIM-HOMEOBOX PROTEIN LMX1_MESAU, gene found by Glimmer
03_1180, SUBTILISIN-RELATED ENDOPEPTIDASE K, PRTK_TRIAL, gene found by Glimmer
03_1190, THIOREDOXIN PEROXIDASE (THIOL-SPECIFIC ANTIOXIDANT PROTEIN), TDX_FASHE, TSA1_yeast, gene found by Glimmer
03_1220, 60S RIBOSOMAL PROTEIN L3, RL3_RAT, gene found by Glimmer
03_1230, similarity to PERIODIC TRYPTOPHAN PROTEIN 1 (WD repeats-containing protein), PWP1_HUMAN, gene found by Glimmer
03_1240, similarity to HYPOTHETICAL PROTEIN YGW1_yeast, gene found by Glimmer
phosphatidylinositol N-acetylglucosaminyltransferase
03_1260, ENDOPLASMIC RETICULUM MEMBRANE PROTEIN INVOLVED IN THE REGULATION OF THE RETENTION OF ER RESIDENT PROTEINS,G25L_CANFA, gene found by Glimmer
03_1270, CYTIDYLATE KINASE (CYTIDINE MONOPHOSPHATE KINASE), KCY_BACSU, gene found by Glimmer
03_1290, similarity to HYPOTHETICAL PROTEIN YABA_SCHPO, gene found by Glimmer
tRNA found by tRNAscan-SE, tRNA type: Val, Anticodon: TAC, Score: 66.98
proteasome regulatory particle base subunit RPT1
03_1330, 26S PROTEASOME REGULATORY SUBUNIT 7, PRS7_HUMAN, gene found by Glimmer
03_1350, GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE (PEPTIDE N-MYRISTOYLTRANSFERASE), NMT1_MOUSE, NMT1_yeast, gene found by Glimmer
03_1360, similarity to HYPOTHETICAL PROTEIN YEY6_yeast, gene found by Glimmer
03_1370, HISTONE DEACETYLASE 1, HDA1_CHICK, gene found by Glimmer
03_1380, similarity to PELOTA PROTEIN (NUCLEAR PROTEIN REQUIRED FOR MITOSIS AND MEIOSIS), PELO_DROME, gene found by Glimmer
03_1390, similarity to HYPOTHETICAL PROTEIN YKP1_yeast, gene found by Glimmer
03_1410, SEC18-LIKE VESICULAR FUSION PROTEIN, SEC18_yeast, gene found by Glimmer
03_1430, similarity to RAS-LIKE GTP-BINDING PROTEIN YPT1, YPT1_SCHPO, gene found by Glimmer
03_1440, tRNA ADENILYL TRANSFERASE (tRNA CCA PYROPHOSPHORYLASE), CCA1_yeast, gene found by Glimmer
03_1460, HISTONE H3, H3_CAEEL, gene found by Glimmer
03_1490, 60S RIBOSOMAL PROTEIN L18, RL18_XENLA, gene found by Glimmer
03_1510, unclear, with some similarity to transcriptional activator HAP2_yeast, gene found by Glimmer
03_1520, similarity to CDC20 (WD-repeat protein), YGA3_yeast, gene found by Glimmer
03_1530, similarity to HELICASE MOT1 (REMOVES TBP FROM THE TATA BOX, SNF2/RAD54 FAMILY), MOT1_yeast, gene found by Glimmer
03_1540, similarity to HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN YQ55_CAEEL, gene found by Glimmer
03_1550, leucine zipper domain, gene found by Glimmer
03_1560, similarity to RAS-RELATED CELL DIVISION PROTEIN 42 (GTP-BINDING PROTEIN INVOLVED IN CELL POLARITY), RAC1_CAEEL, CC42_SCHPO, gene found by Glimmer
03_1570, MYOSIN REGULATORY LIGHT CHAIN, MLRH_CAEEL, gene found by Glimmer
03_1580, unknown, v11.12, gene found by Glimmer
03_1590, ANKYRIN REPEAT-CONTAINING PROTEIN, ANK1_MOUSE, gene found by Glimmer
03_1600, similarity to putative TRANSCRIPTION INITIATION FACTOR TFIIF SMALL SUBUNIT (TRANSCRIPTION FACTOR G 30kDa SUBUNIT, ANC1 PROTEIN), YD67_SCHPO,gene found by Glimmer