Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Flasuviricetes; Amarillovirales; Flaviviridae; Hepacivirus; Hepacivirus platyrrhini.
Toward a surrogate model for hepatitis C virus: An infectious molecular clone of the GB virus-B hepatitis agent
Submitted (18-NOV-2003) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (23-AUG-1999) Hepatitis Viruses Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 7, Room 201, 7 Center Dr. 0740, Bethesda, MD 20892, USA
REVIEWED REFSEQ: This record has been curated by NCBI staff. The\nreference sequence was derived from AF179612.\nThe mature peptides were predicted and annotated by the NCBI staff\nby analogy with those of Hepatitis C virus.\nCOMPLETENESS: full length.
Cleavage sites were added by NCBI staff based on homology to other hepaciviruses and these sources: PMID: 25926652, PMID: 26038514, PMID: 23572554, PMID: 16492760
non-experimental evidence, no additional details recorded
E2/p13 and p13/NS2 cleavage sites annotated according to experimental evidence reported in PMID: 16492760
E2/p6 and p6/p7 cleavage sites annotated according to experimental evidence reported in PMID: 16492760, which also reported that p6 may not be necessary in vivo
p6/p7 and p7/NS2 cleavage sites annotated according to experimental evidence reported in PMID: 16492760. There was some evidence the protein may also be cleaved at amino acid 681/682 (genomic position 2488/2489)
NS3 serine protease/NS3P/ATPase/helicase peptide/hepacivirin
NS5B RNA-dependent RNA polymerase peptide; RdRp