Streptomyces genisteinicus strain CRPJ-33 plasmid unnamed2.
Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales; Streptomycetaceae; Streptomyces.
Submitted (28-AUG-2020) School of Life Science, Hunan University of Science and Technology, He Ping Street, Xiangtan, Hunan 411201, China
REFSEQ INFORMATION: The reference sequence is identical to\nCP060826.1.\nThe annotation was added by the NCBI Prokaryotic Genome Annotation\nPipeline (PGAP). Information about PGAP can be found here:\nhttps://www.ncbi.nlm.nih.gov/genome/annotation_prok/\n\n##Genome-Assembly-Data-START##\nAssembly Date :: 20-AUG-2020\nAssembly Method :: HGAP v. 2.3\nGenome Representation :: Full\nExpected Final Version :: No\nGenome Coverage :: 100.0x\nSequencing Technology :: Oxford Nanopore\n##Genome-Assembly-Data-END##\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: NCBI RefSeq\nAnnotation Date :: 05/06/2023 07:06:36\nAnnotation Pipeline :: NCBI Prokaryotic Genome\n Annotation Pipeline (PGAP)\nAnnotation Method :: Best-placed reference protein\n set; GeneMarkS-2+\nAnnotation Software revision :: 6.5\nFeatures Annotated :: Gene; CDS; rRNA; tRNA; ncRNA\nGenes (total) :: 6,816\nCDSs (total) :: 6,721\nGenes (coding) :: 6,626\nCDSs (with protein) :: 6,626\nGenes (RNA) :: 95\nrRNAs :: 6, 6, 6 (5S, 16S, 23S)\ncomplete rRNAs :: 6, 6, 6 (5S, 16S, 23S)\ntRNAs :: 74\nncRNAs :: 3\nPseudo Genes (total) :: 101\nCDSs (without protein) :: 95\nPseudo Genes (ambiguous residues) :: 0 of 101\nPseudo Genes (frameshifted) :: 36 of 101\nPseudo Genes (incomplete) :: 71 of 101\nPseudo Genes (internal stop) :: 6 of 101\nPseudo Genes (multiple problems) :: 17 of 101\nCRISPR Arrays :: 3\n##Genome-Annotation-Data-END##
type strain of Streptomyces genisteinicus
COORDINATES: similar to AA sequence:RefSeq:WP_011530435.1
GO:0004803 - transposase activity [Evidence IEA]
Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: protein motif:HMM:NF012493.2
COORDINATES: protein motif:HMM:NF016724.2
GO:0005524 - ATP binding [Evidence IEA]; GO:0003677 - DNA binding [Evidence IEA]; GO:0016787 - hydrolase activity [Evidence IEA]
incomplete; partial in the middle of a contig; missing C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_020524619.1
COORDINATES: ab initio prediction:GeneMarkS-2+
Derived by automated computational analysis using gene prediction method: GeneMarkS-2+.
COORDINATES: similar to AA sequence:RefSeq:WP_019357604.1
COORDINATES: similar to AA sequence:RefSeq:WP_018808914.1
COORDINATES: protein motif:HMM:TIGR00619.1
COORDINATES: protein motif:HMM:NF024867.2
COORDINATES: protein motif:HMM:NF039695.1
COORDINATES: protein motif:HMM:NF013073.2
COORDINATES: similar to AA sequence:RefSeq:WP_018104847.1
COORDINATES: similar to AA sequence:RefSeq:WP_020114933.1
COORDINATES: similar to AA sequence:RefSeq:WP_010063816.1
COORDINATES: similar to AA sequence:RefSeq:WP_017949262.1
COORDINATES: similar to AA sequence:RefSeq:WP_012932396.1
COORDINATES: protein motif:HMM:NF012388.2
GO:0030598 - rRNA N-glycosylase activity [Evidence IEA]
GO:0017148 - negative regulation of translation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_003972049.1
GO:0020037 - heme binding [Evidence IEA]
GO:0016787 - hydrolase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020123336.1
DNA starvation/stationary phase protection protein
COORDINATES: similar to AA sequence:RefSeq:WP_015143526.1
COORDINATES: similar to AA sequence:RefSeq:WP_014442349.1
COORDINATES: similar to AA sequence:RefSeq:WP_014442350.1
COORDINATES: similar to AA sequence:RefSeq:WP_014442351.1
COORDINATES: similar to AA sequence:RefSeq:WP_014445441.1
helix-turn-helix domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_018530329.1
GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]
GO:0005975 - carbohydrate metabolic process [Evidence IEA]
glycoside hydrolase family 3 C-terminal domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_019985282.1
COORDINATES: similar to AA sequence:RefSeq:WP_009192657.1
COORDINATES: similar to AA sequence:RefSeq:WP_006132491.1
GO:0030246 - carbohydrate binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_009192650.1
GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; GO:0043565 - sequence-specific DNA binding [Evidence IEA]; GO:0000976 - transcription cis-regulatory region binding [Evidence IEA]
GO:0006351 - DNA-templated transcription [Evidence IEA]; GO:0045892 - negative regulation of DNA-templated transcription [Evidence IEA]; GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]
LacI family DNA-binding transcriptional regulator
COORDINATES: similar to AA sequence:RefSeq:WP_019524901.1
GO:0022857 - transmembrane transporter activity [Evidence IEA]
GO:0055085 - transmembrane transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010313684.1
GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; GO:0016491 - oxidoreductase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_003997706.1
COORDINATES: similar to AA sequence:RefSeq:WP_018530429.1
COORDINATES: similar to AA sequence:RefSeq:WP_015031581.1
GO:0004722 - protein serine/threonine phosphatase activity [Evidence IEA]
PP2C family protein-serine/threonine phosphatase
COORDINATES: similar to AA sequence:RefSeq:WP_012921429.1
COORDINATES: similar to AA sequence:RefSeq:WP_018739879.1
COORDINATES: similar to AA sequence:RefSeq:WP_019066087.1
COORDINATES: similar to AA sequence:RefSeq:WP_018540726.1
COORDINATES: similar to AA sequence:RefSeq:WP_020739711.1
winged helix-turn-helix domain-containing protein
COORDINATES: protein motif:HMM:NF019928.2
COORDINATES: similar to AA sequence:RefSeq:WP_015663150.1
GDSL-type esterase/lipase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_010047369.1
COORDINATES: similar to AA sequence:RefSeq:WP_018893210.1
COORDINATES: similar to AA sequence:RefSeq:WP_019355503.1
GO:0042546 - cell wall biogenesis [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_019889940.1
LysR substrate-binding domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_018538234.1
GO:0046872 - metal ion binding [Evidence IEA]
maleylpyruvate isomerase family mycothiol-dependent enzyme
COORDINATES: similar to AA sequence:RefSeq:WP_006239371.1
COORDINATES: similar to AA sequence:RefSeq:WP_016334911.1
COORDINATES: protein motif:HMM:TIGR03086.1
COORDINATES: similar to AA sequence:RefSeq:WP_014158107.1
COORDINATES: similar to AA sequence:RefSeq:WP_015608106.1
COORDINATES: protein motif:HMM:NF025030.2
COORDINATES: similar to AA sequence:RefSeq:WP_018560459.1
COORDINATES: similar to AA sequence:RefSeq:WP_003964274.1
COORDINATES: similar to AA sequence:RefSeq:WP_020132722.1
GO:0046872 - metal ion binding [Evidence IEA]; GO:0016717 - oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water [Evidence IEA]
GO:0006633 - fatty acid biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004979480.1
COORDINATES: similar to AA sequence:RefSeq:WP_018729862.1
CGNR zinc finger domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_018729863.1
COORDINATES: similar to AA sequence:RefSeq:WP_017948768.1
GO:0006812 - monoatomic cation transport [Evidence IEA]; GO:0055085 - transmembrane transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_003964028.1
COORDINATES: similar to AA sequence:RefSeq:WP_012998197.1
COORDINATES: similar to AA sequence:RefSeq:WP_019355004.1
COORDINATES: similar to AA sequence:RefSeq:WP_014044462.1
COORDINATES: similar to AA sequence:RefSeq:WP_016574917.1
COORDINATES: similar to AA sequence:RefSeq:WP_007457070.1
COORDINATES: similar to AA sequence:RefSeq:WP_012378918.1
COORDINATES: similar to AA sequence:RefSeq:WP_008735189.1
COORDINATES: similar to AA sequence:RefSeq:WP_018519173.1
COORDINATES: protein motif:HMM:NF024945.2
Derived by automated computational analysis using gene prediction method: tRNAscan-SE.
COORDINATES: similar to AA sequence:RefSeq:WP_006136481.1
COORDINATES: similar to AA sequence:RefSeq:WP_020540297.1
GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]
GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_019527507.1
nucleotidyl transferase AbiEii/AbiGii toxin family protein
COORDINATES: similar to AA sequence:RefSeq:WP_004924321.1
COORDINATES: similar to AA sequence:RefSeq:WP_013285644.1
COORDINATES: similar to AA sequence:RefSeq:WP_018087882.1
COORDINATES: protein motif:HMM:NF012901.2
SDR family NAD(P)-dependent oxidoreductase
COORDINATES: similar to AA sequence:RefSeq:WP_014173973.1
GO:0043880 - crotonyl-CoA reductase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010982391.1
COORDINATES: protein motif:HMM:NF012296.2
COORDINATES: similar to AA sequence:RefSeq:WP_016331893.1
GO:0008483 - transaminase activity [Evidence IEA]
DegT/DnrJ/EryC1/StrS family aminotransferase
COORDINATES: similar to AA sequence:RefSeq:WP_006537964.1
NDP-hexose 2,3-dehydratase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_018846535.1
GO:0008168 - methyltransferase activity [Evidence IEA]; GO:1904047 - S-adenosyl-L-methionine binding [Evidence IEA]
COORDINATES: protein motif:HMM:TIGR04516.1
activator-dependent family glycosyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_005486647.1
COORDINATES: protein motif:HMM:NF013315.2
methyltransferase domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_020392218.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0046872 - metal ion binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_009717707.1
COORDINATES: similar to AA sequence:RefSeq:WP_003998996.1
GO:0008080 - N-acetyltransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_013000725.1
COORDINATES: similar to AA sequence:RefSeq:WP_014137308.1
GO:0005886 - plasma membrane [Evidence IEA]
GO:0051991 - UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D- glutamyl-meso-2, 6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity [Evidence IEA]; GO:0050511 - undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity [Evidence IEA]
GO:0005975 - carbohydrate metabolic process [Evidence IEA]; GO:0007049 - cell cycle [Evidence IEA]; GO:0051301 - cell division [Evidence IEA]; GO:0071555 - cell wall organization [Evidence IEA]; GO:0030259 - lipid glycosylation [Evidence IEA]; GO:0009252 - peptidoglycan biosynthetic process [Evidence IEA]; GO:0008360 - regulation of cell shape [Evidence IEA]
UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
COORDINATES: similar to AA sequence:RefSeq:WP_005464225.1
NAD-dependent epimerase/dehydratase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_018738305.1
GO:0008830 - dTDP-4-dehydrorhamnose 3,5-epimerase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_018787832.1
COORDINATES: similar to AA sequence:RefSeq:WP_014057315.1
COORDINATES: similar to AA sequence:RefSeq:WP_010981855.1
COORDINATES: similar to AA sequence:RefSeq:WP_004561327.1
COORDINATES: similar to AA sequence:RefSeq:WP_014060791.1
COORDINATES: similar to AA sequence:RefSeq:WP_020546006.1
COORDINATES: similar to AA sequence:RefSeq:WP_012381767.1
COORDINATES: protein motif:HMM:NF020243.2
COORDINATES: similar to AA sequence:RefSeq:WP_005452380.1
COORDINATES: similar to AA sequence:RefSeq:WP_017949434.1
GO:0007059 - chromosome segregation [Evidence IEA]; GO:0000910 - cytokinesis [Evidence IEA]
ParB/RepB/Spo0J family partition protein
COORDINATES: similar to AA sequence:RefSeq:WP_018106296.1
COORDINATES: similar to AA sequence:RefSeq:WP_018893253.1
GO:0008171 - O-methyltransferase activity [Evidence IEA]
frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_018846083.1
GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; GO:0043565 - sequence-specific DNA binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_014140738.1
COORDINATES: similar to AA sequence:RefSeq:WP_010636357.1
GO:0003896 - DNA primase activity [Evidence IEA]
GO:0006260 - DNA replication [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010636356.1
COORDINATES: similar to AA sequence:RefSeq:WP_014158410.1
COORDINATES: similar to AA sequence:RefSeq:WP_020555800.1
COORDINATES: similar to AA sequence:RefSeq:WP_018512617.1
COORDINATES: similar to AA sequence:RefSeq:WP_018106290.1
COORDINATES: similar to AA sequence:RefSeq:WP_007387458.1
ScbR family autoregulator-binding transcription factor
COORDINATES: protein motif:HMM:NF041195.1
ScbA/BarX family gamma-butyrolactone biosynthesis protein
COORDINATES: similar to AA sequence:RefSeq:WP_018548737.1
COORDINATES: similar to AA sequence:RefSeq:WP_018106319.1
AfsR/SARP family transcriptional regulator
COORDINATES: protein motif:HMM:NF012759.2
COORDINATES: similar to AA sequence:RefSeq:WP_018568309.1
GO:0008897 - holo-[acyl-carrier-protein] synthase activity [Evidence IEA]; GO:0000287 - magnesium ion binding [Evidence IEA]
4'-phosphopantetheinyl transferase superfamily protein
COORDINATES: protein motif:HMM:NF022072.2
COORDINATES: similar to AA sequence:RefSeq:WP_018106303.1
COORDINATES: protein motif:HMM:NF012873.2
COORDINATES: similar to AA sequence:RefSeq:WP_004994442.1
COORDINATES: protein motif:HMM:NF024589.2
COORDINATES: similar to AA sequence:RefSeq:WP_018568314.1
COORDINATES: similar to AA sequence:RefSeq:WP_017601708.1
COORDINATES: similar to AA sequence:RefSeq:WP_018682366.1
GO:0008460 - dTDP-glucose 4,6-dehydratase activity [Evidence IEA]
GO:0019305 - dTDP-rhamnose biosynthetic process [Evidence IEA]; GO:0009243 - O antigen biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010072403.1
GO:0008879 - glucose-1-phosphate thymidylyltransferase activity [Evidence IEA]
GO:0000271 - polysaccharide biosynthetic process [Evidence IEA]
glucose-1-phosphate thymidylyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_020497363.1
GO:0051287 - NAD binding [Evidence IEA]; GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]; GO:0003979 - UDP-glucose 6-dehydrogenase activity [Evidence IEA]
amino acid adenylation domain-containing protein
COORDINATES: protein motif:HMM:NF013672.2
GO:0016810 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds [Evidence IEA]
polysaccharide deacetylase family protein
COORDINATES: protein motif:HMM:NF019310.2
COORDINATES: protein motif:HMM:NF014805.2
COORDINATES: similar to AA sequence:RefSeq:WP_005316720.1
COORDINATES: protein motif:HMM:NF014653.2
COORDINATES: protein motif:HMM:NF013567.2
GO:0016491 - oxidoreductase activity [Evidence IEA]; GO:0016651 - oxidoreductase activity, acting on NAD(P)H [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020541170.1
GO:0003824 - catalytic activity [Evidence IEA]
sugar phosphate isomerase/epimerase family protein
COORDINATES: protein motif:HMM:NF024860.2
COORDINATES: similar to AA sequence:RefSeq:WP_015621115.1
COORDINATES: protein motif:HMM:NF025025.2
COORDINATES: similar to AA sequence:RefSeq:WP_005310269.1
GO:0004020 - adenylylsulfate kinase activity [Evidence IEA]
GO:0006790 - sulfur compound metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_017944697.1
GO:0004781 - sulfate adenylyltransferase (ATP) activity [Evidence IEA]
GO:0019419 - sulfate reduction [Evidence IEA]
sulfate adenylyltransferase subunit CysD
COORDINATES: similar to AA sequence:RefSeq:WP_019434150.1
GO:0005525 - GTP binding [Evidence IEA]; GO:0003924 - GTPase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_016574327.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0016887 - ATP hydrolysis activity [Evidence IEA]
COORDINATES: protein motif:HMM:NF012738.2
acyltransferase domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_010315905.1
GO:0008703 - 5-amino-6-(5-phosphoribosylamino)uracil reductase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_006130283.1
COORDINATES: protein motif:HMM:NF013166.2
GO:0009058 - biosynthetic process [Evidence IEA]
GO:0016740 - transferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_015114252.1
GO:0070403 - NAD+ binding [Evidence IEA]
GO:0006631 - fatty acid metabolic process [Evidence IEA]
3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_012826354.1
COORDINATES: similar to AA sequence:RefSeq:WP_007358389.1
GO:0016627 - oxidoreductase activity, acting on the CH-CH group of donors [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_012828062.1
COORDINATES: similar to AA sequence:RefSeq:WP_014987469.1
COORDINATES: similar to AA sequence:RefSeq:WP_012381769.1
GO:0016491 - oxidoreductase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_013285638.1
COORDINATES: similar to AA sequence:RefSeq:WP_015034975.1
COORDINATES: similar to AA sequence:RefSeq:WP_020634404.1
COORDINATES: similar to AA sequence:RefSeq:WP_020666755.1
COORDINATES: similar to AA sequence:RefSeq:WP_007387428.1
COORDINATES: similar to AA sequence:RefSeq:WP_013477263.1
COORDINATES: similar to AA sequence:RefSeq:WP_016573074.1
GO:0004013 - adenosylhomocysteinase activity [Evidence IEA]
GO:0006730 - one-carbon metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020133210.1
GO:0004489 - methylenetetrahydrofolate reductase (NAD(P)H) activity [Evidence IEA]
GO:0009086 - methionine biosynthetic process [Evidence IEA]
methylenetetrahydrofolate reductase [NAD(P)H]
COORDINATES: similar to AA sequence:RefSeq:WP_019059730.1
GO:0004478 - methionine adenosyltransferase activity [Evidence IEA]
GO:0006556 - S-adenosylmethionine biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_003967670.1
TIGR04222 domain-containing membrane protein
COORDINATES: similar to AA sequence:RefSeq:WP_009192135.1
COORDINATES: similar to AA sequence:RefSeq:WP_018825357.1
COORDINATES: similar to AA sequence:RefSeq:WP_016469098.1
COORDINATES: similar to AA sequence:RefSeq:WP_010072532.1
COORDINATES: similar to AA sequence:RefSeq:WP_018569446.1
COORDINATES: similar to AA sequence:RefSeq:WP_003971372.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0004519 - endonuclease activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_005321066.1
COORDINATES: protein motif:HMM:NF015422.2
GO:0003676 - nucleic acid binding [Evidence IEA]
helicase associated domain-containing protein