Saccharomyces paradoxus chromosome II, complete sequence.
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
Contrasting evolutionary genome dynamics between domesticated and wild yeasts
Population-level Yeast Reference Genomes
Submitted (28-APR-2020) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (20-JAN-2020) Biotechnology, Delft University of Technology, van der Maasweg 9, Delft, Netherlands 2629 HZ, Netherlands
Submitted (04-FEB-2017) Institute for Research on Cancer and Aging, Nice (IRCAN), Institute for Research on Cancer and Aging, Nice (IRCAN), 28 Avenue de Valombrose, Nice, PACA 06107, France
PROVISIONAL REFSEQ: This record has not yet been subject to final\nNCBI review. The reference sequence is identical to CP020243.\n\n##Genome-Assembly-Data-START##\nAssembly Date :: 29-JAN-2017\nAssembly Method :: HGAP v. 2.3.0\nAssembly Name :: S. paradoxus CBS432 PacBio Assembly\nGenome Representation :: Full\nExpected Final Version :: Yes\nGenome Coverage :: 112.0x\nSequencing Technology :: PacBio\n##Genome-Assembly-Data-END##\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: INSDC submitter\nAnnotation Status :: Full annotation\nAnnotation Pipeline :: Eukaryotic Annotation Propagation Pipeline\n##Genome-Annotation-Data-END##\nCOMPLETENESS: full length.
culture from neotype of Saccharomyces paradoxus
aryl-alcohol dehydrogenase; similar to YCR107W
zinc cluster transcription factor; similar to YCR106W
NADPH-dependent medium chain alcohol dehydrogenase; similar to YCR105W
Protein with roles in exocytosis and cation homeostasis; similar to YBL106C
Protein serine/threonine kinase; similar to YBL105C
Subunit of the SEA (Seh1-associated) complex; similar to YBL104C
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways; similar to YBL103C
Tetra-spanning membrane protein found mostly in the late Golgi; similar to YBL102W
Protein involved in regulating endocytosis of plasma membrane proteins; similar to YBL101C
Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase; similar to YBL099W
Kynurenine 3-mono oxygenase; similar to YBL098W
Subunit of the condensin complex; similar to YBL097W
Subunit of the RNA polymerase II mediator complex; similar to YBL093C
Ribosomal 60S subunit protein L32; similar to YBL092W
Methionine aminopeptidase; similar to YBL091C
Mitochondrial ribosomal protein of the small subunit; similar to YBL090W
Protein kinase primarily involved in telomere length regulation; similar to YBL088C
Protein implicated in polar growth; similar to YBL085W
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C); similar to YBL084C
Dolichol-P-Man dependent alpha(1-3) mannosyltransferase; similar to YBL082C
Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex; similar to YBL080C
Subunit of the inner ring of the nuclear pore complex (NPC); similar to YBL079W
Component of autophagosomes and Cvt vesicles; similar to YBL078C
Cytoplasmic isoleucine-tRNA synthetase; similar to YBL076C
ATPase involved in protein folding and the response to stress; similar to YBL075C
Component of the U5 snRNP complex; similar to YBL074C
Protein component of the small (40S) ribosomal subunit; similar to YBL072C
Lipid raft associated protein; similar to YBL069W
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP; similar to YBL068W
Ubiquitin-specific protease that cleaves Ub-protein fusions; similar to YBL067C
transcription factor; similar to YBL066C
Mitochondrial peroxiredoxin with thioredoxin peroxidase activity; similar to YBL064C
Kinesin-related motor protein; similar to YBL063W
Activator of Chs3p (chitin synthase III) during vegetative growth; similar to YBL061C
Guanine nucleotide exchange factor specific for Arf3p; similar to YBL060W
UBX (ubiquitin regulatory X) domain-containing protein; similar to YBL058W
One of two mitochondrially-localized peptidyl-tRNA hydrolases; similar to YBL057C
Type 2C protein phosphatase (PP2C); similar to YBL056W
3'-->5' exonuclease and endonuclease with a possible role in apoptosis; similar to YBL055C
PAC motif binding protein involved in rRNA and ribosome biogenesis; similar to YBL054W
Histone acetyltransferase catalytic subunit of NuA3 complex; similar to YBL052C
Protein involved in G2/M phase progression and response to DNA damage; similar to YBL051C
Alpha-SNAP cochaperone; similar to YBL050W
Scaffold protein involved in the formation of early endocytic sites; similar to YBL047C
Regulatory subunit of protein phosphatase PP4; similar to YBL046W
Core subunit of the ubiquinol-cytochrome c reductase complex; similar to YBL045C
High affinity uridine permease, localizes to the plasma membrane; similar to YBL042C
Beta 6 subunit of the 20S proteasome; similar to YBL041W
Major CTP synthase isozyme (see also URA8); similar to YBL039C
Mitochondrial ribosomal protein of the large subunit; similar to YBL038W
non-specific single-domain racemase; similar to YBL036C
B subunit of DNA polymerase alpha-primase complex; similar to YBL035C
Component of the mitotic spindle; similar to YBL034C
GTP cyclohydrolase II; similar to YBL033C
RNA binding protein involved in asymmetric localization of ASH1 mRNA; similar to YBL032W
Mitotic spindle protein; similar to YBL031W
Major ADP/ATP carrier of the mitochondrial inner membrane; similar to YBL030C
Ribosomal 60S subunit protein L19B; similar to YBL027W
Lsm (Like Sm) protein; similar to YBL026W
Protein involved in promoting high level transcription of rDNA; similar to YBL025W
S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase; similar to YBL024W
Protein involved in DNA replication; similar to YBL023C
ATP-dependent Lon protease; similar to YBL022C
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex; similar to YBL021C
Membrane protein required for translocation of Man5GlcNac2-PP-Dol; similar to YBL020W
Class II abasic (AP) endonuclease involved in repair of DNA damage; similar to YBL019W
Subunit of both RNase MRP and nuclear RNase P; similar to YBL018C
Type I transmembrane sorting receptor for multiple vacuolar hydrolases; similar to YBL017C
Mitogen-activated serine/threonine protein kinase involved in mating; similar to YBL016W
Protein with CoA transferase activity; similar to YBL015W
Component of the core factor (CF) rDNA transcription factor complex; similar to YBL014C
Methionyl-tRNA formyltransferase; similar to YBL013W
Glycerol 3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase; similar to YBL011W
Subunit of the HIR complex; similar to YBL008W
Cytoskeletal protein binding protein; similar to YBL007C
Component of the RSC chromatin remodeling complex; similar to YBL006C
Transcriptional activator of the pleiotropic drug resistance network; similar to YBL005W
Component of the small-subunit (SSU) processome; similar to YBL004W
neutral trehalase, required for thermotolerance; similar to YBR001C
Cis-prenyltransferase involved in dolichol synthesis; similar to YBR002C
Hexaprenyl pyrophosphate synthetase; similar to YBR003W
Protein of the ER membrane involved in cell wall chitin deposition; similar to YBR005W
Succinate semialdehyde dehydrogenase; similar to YBR006W
suppressor of mpt5 mutation; similar to YBR007C
Plasma membrane transporter of the major facilitator superfamily; similar to YBR008C
Cytoplasmic inorganic pyrophosphatase (PPase); similar to YBR011C
Cis-golgi localized monothiol glutaredoxin; similar to YBR014C
Alpha-1,2-mannosyltransferase; similar to YBR015C
Tail-anchored plasma membrane protein with a conserved CYSTM module; similar to YBR016W
Transportin or cytosolic karyopherin beta 2; similar to YBR017C
Galactose-1-phosphate uridyl transferase; similar to YBR018C
UDP-glucose-4-epimerase; similar to YBR019C
Plasma membrane localized uracil permease; similar to YBR021W
Phosphatase that is highly specific for ADP-ribose 1''-phosphate; similar to YBR022W
Protein anchored to mitochondrial inner membrane; similar to YBR024W
P-loop ATPase with similarity to OLA1 and bacterial YchF; similar to YBR025C
2-enoyl thioester reductase; similar to YBR026C
Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase); similar to YBR029C
Ribosomal lysine methyltransferase; similar to YBR030W
Ribosomal 60S subunit protein L4B; similar to YDR012W
zinc cluster protein, predicted to be a transcription factor; similar to YBR033W
Nuclear SAM-dependent mono- and asymmetric methyltransferase; similar to YBR034C
Pyridoxine (pyridoxamine) phosphate oxidase; similar to YBR035C
Endoplasmic reticulum membrane protein; similar to YBR036C
Copper-binding protein of mitochondrial inner membrane; similar to YBR037C
Gamma subunit of the F1 sector of mitochondrial F1F0 ATP synthase; similar to YBR039W
Integral membrane protein required for efficient mating; similar to YBR040W
Very long chain fatty acyl-CoA synthetase and fatty acid transporter; similar to YBR041W
transferase involved in phospholipid biosynthesis; similar to YBR042C
Multidrug transporter of the major facilitator superfamily; similar to YBR043C
Protein involved in assembly of the succinate dehydrogenase complex; similar to YBR044C
Meiosis-specific regulatory subunit of the Glc7p protein phosphatase; similar to YBR045C
NADPH-dependent quinone reductase; similar to YBR046C
Protein component of the small (40S) ribosomal subunit; similar to YDR025W
RNA polymerase I enhancer binding protein; similar to YBR049C
Regulatory subunit of the Glc7p type-1 protein phosphatase; similar to YBR050C
Protein with a role in response to acid stress; similar to YBR054W
glycoside hydrolase of the mitochondrial intermembrane space; similar to YBR056W
Protein essential for meiotic DNA replication and sporulation; similar to YBR057C
Ubiquitin-specific protease; similar to YBR058C
Ser-Thr protein kinase; similar to YBR059C
Subunit of the origin recognition complex (ORC); similar to YBR060C
2'-O-ribose methyltransferase; similar to YBR061C
Pre-mRNA splicing factor; similar to YBR065C
Transcriptional repressor; similar to YBR066C
Major cell wall mannoprotein with possible lipase activity; similar to YBR067C
High-affinity leucine permease; similar to YBR068C
Amino acid transporter for valine, leucine, isoleucine, and tyrosine; similar to YBR069C
Component of UDP-GlcNAc transferase; similar to YBR070C
Small heat shock protein (sHSP) with chaperone activity; similar to YBR072W
DNA-dependent ATPase; similar to YBR073W
Multi-spanning vacuolar membrane protease; similar to YBR074W
Component of the EGO and GSE complexes; similar to YBR077C
eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3); similar to YBR079C
AAA ATPase and SNARE disassembly chaperone; similar to YBR080C
Subunit of the SAGA transcriptional regulatory complex; similar to YBR081C
Ubiquitin-conjugating enzyme (E2); similar to YBR082C
Transcription factor targeting filamentation genes and Ty1 expression; similar to YBR083W
Mitochondrial C1-tetrahydrofolate synthase; similar to YBR084W
Mitochondrial inner membrane ADP/ATP translocator; similar to YBR085W
Cortical ER protein involved in ER-plasma membrane tethering; similar to YBR086C
Subunit of heteropentameric Replication factor C (RF-C); similar to YBR087W
Proliferating cell nuclear antigen (PCNA); similar to YBR088C
Essential protein of the inner mitochondrial membrane; similar to YBR091C
Constitutively expressed acid phosphatase similar to Pho5p; similar to YBR092C
Repressible acid phosphatase; similar to YBR093C
tubulin tyrosine ligase associated with P-bodies; similar to YBR094W
Component of the histone deacetylase Rpd3L complex; similar to YBR095C
Serine/threonine protein kinase involved in vacuolar protein sorting; similar to YBR097W
Subunit of structure-specific Mms4p-Mus81p endonuclease; similar to YBR098W
Hsp70 (Ssa1p) nucleotide exchange factor; similar to YBR101C
Exocyst subunit with dual roles in exocytosis and spliceosome assembly; similar to YBR102C
WD40 repeat-containing subunit of Set3C histone deacetylase complex; similar to YBR103W
mitochondrial inner membrane transporter; similar to YBR104W
GID Complex regulatory subunit; similar to YBR105C
Probable membrane protein; similar to YBR106W
Outer kinetochore protein and component of the Ctf19 complex; similar to YBR107C
Protein that inhibits barbed-end actin filament elongation; similar to YBR108W
Nudix hydrolase family member with ADP-ribose pyrophosphatase activity; similar to YBR111C
General transcriptional co-repressor; similar to YBR112C
Nucleotide excision repair (NER) protein; similar to YBR114W
Alpha aminoadipate reductase; similar to YBR115C
Translational elongation factor EF-1 alpha; similar to YBR118W
Mitochondrial protein required for translation of the COB mRNA; similar to YBR120C
Cytoplasmic and mitochondrial glycyl-tRNA synthase; similar to YBR121C
Mitochondrial ribosomal protein of the large subunit; similar to YBR122C
Subunit of RNA polymerase III transcription initiation factor complex; similar to YBR123C
Cytoplasmic type 2C protein phosphatase (PP2C); similar to YBR125C
Synthase subunit of trehalose-6-P synthase/phosphatase complex; similar to YBR126C
Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase; similar to YBR127C
Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I; similar to YBR128C
Protein adaptor between Myo4p and the She2p-mRNA complex; similar to YBR130C
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF); similar to YBR131W
Plasma membrane regulator of polyamine and carnitine transport; similar to YBR132C
Protein arginine N-methyltransferase; similar to YBR133C
Cyclin-dependent protein kinase regulatory subunit and adaptor; similar to YBR135W
DNA integrity checkpoint protein and PI kinase superfamily member; similar to YBR136W
Protein with a role in ER delivery of tail-anchored membrane proteins; similar to YBR137W
serine type carboxypeptidase; similar to YBR139W
GTPase-activating protein; similar to YBR140C
Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase; similar to YBR141C
Essential nucleolar protein; similar to YBR142W
Polypeptide release factor (eRF1) in translation termination; similar to YBR143C
Alcohol dehydrogenase isoenzyme V; similar to YBR145W
Mitochondrial ribosomal protein of the small subunit; similar to YBR146W
vacuolar membrane transporter for cationic amino acids; similar to YBR147W
Protein required for normal prospore membrane formation; similar to YBR148W
NADP+ dependent arabinose dehydrogenase; similar to YBR149W
mRNA splicing factor, component of U4/U6.U5 tri-snRNP; similar to YBR152W
Diaminohydroxyphoshoribosylaminopyrimidine deaminase; similar to YBR153W
RNA polymerase subunit ABC27; similar to YBR154C
TPR-containing co-chaperone; similar to YBR155W
Subunit of the conserved chromosomal passenger complex (CPC); similar to YBR156C
Protein required for daughter cell separation; similar to YBR158W
Microsomal beta-keto-reductase; similar to YBR159W
Cyclin-dependent kinase (CDK) catalytic subunit; similar to YBR160W
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit; similar to YBR161W
Mitochondrial 5'-3' exonuclease and sliding exonuclease; similar to YBR163W
Soluble GTPase with a role in regulation of membrane traffic; similar to YBR164C
Ubiquitin-conjugating enzyme suppressor that regulates Cdc34p; similar to YBR165W
Prephenate dehydrogenase involved in tyrosine biosynthesis; similar to YBR166C
Subunit of both RNase MRP and nuclear RNase P; similar to YBR167C
Peroxisomal integral membrane protein; similar to YBR168W
Member of the heat shock protein 70 (HSP70) family; similar to YBR169C
Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase; similar to YBR170C
Non-essential subunit of Sec63 complex; similar to YBR171W
Chaperone required for correct maturation of the 20S proteasome; similar to YBR173C
Essential subunit of the COMPASS (Set1C) complex; similar to YBR175W
Ketopantoate hydroxymethyltransferase; similar to YBR176W
Acyl-coenzymeA:ethanol O-acyltransferase; similar to YBR177C
dityrosine transporter of the major facilitator superfamily; similar to YBR180W
Plasma membrane sulfite pump involved in sulfite metabolism; similar to YPL092W
Cytosolic and mitochondrial glutathione oxidoreductase; similar to YPL091W
Protein component of the small (40S) ribosomal subunit; similar to YPL090C
MADS-box transcription factor involved in osmotic stress response; similar to YBR182C
Membrane-associated mitochondrial ribosome receptor; similar to YBR185C
Hexameric ring ATPase that remodels chromosome axis protein Hop1p; similar to YBR186W
Member of the NineTeen Complex (NTC); similar to YBR188C
Protein component of the small (40S) ribosomal subunit; similar to YBR189W
Ribosomal 60S subunit protein L21A; similar to YBR191W
Mitochondrial pyrimidine nucleotide transporter; similar to YBR192W
Subunit of the RNA polymerase II mediator complex; similar to YBR193C
Protein proposed to be associated with the nuclear pore complex; similar to YBR194W
Subunit of chromatin assembly factor I (CAF-1); similar to YBR195C
Glycolytic enzyme phosphoglucose isomerase; similar to YBR196C
Subunit (90 kDa) of TFIID and SAGA complexes; similar to YBR198C
mannosyltransferase involved in protein glycosylation; similar to YBR199W
Protein containing SH3-domains; similar to YBR200W
ER membrane protein that promotes export of misfolded polypeptides; similar to YBR201W
Component of the Mcm2-7 hexameric helicase complex; similar to YBR202W
Protein required for antifungal drug ciclopirox olamine resistance; similar to YBR203W
alpha-1,2-mannosyltransferase; similar to YBR205W
high affinity iron transporter; similar to YBR207W
Protein involved in export of proteins from the endoplasmic reticulum; similar to YBR210W
Essential kinetochore protein associated with microtubules and SPBs; similar to YBR211C
RNA binding protein that negatively regulates growth rate; similar to YBR212W
Bifunctional dehydrogenase and ferrochelatase; similar to YBR213W
Protein involved in cell separation during budding; similar to YBR214W
Subunit of the HIR complex; similar to YBR215W
Protein involved in cellular response to oxidative stress; similar to YBR216C
Ubiquitin-like modifier involved in autophagy and the Cvt pathway; similar to YBR217W
Pyruvate carboxylase isoform; similar to YBR218C
E1 beta subunit of the pyruvate dehydrogenase (PDH) complex; similar to YBR221C
Oxalyl-CoA synthetase; similar to YBR222C
Tyrosyl-DNA phosphodiesterase I; similar to YBR223C
Mitochondrial matrix protein; similar to YBR227C
Endonuclease involved in DNA recombination and repair; similar to YBR228W
Glucosidase II catalytic subunit; similar to YBR229C
Mitochondrial outer membrane receptor for cytosolic ribosomes; similar to YBR230C
Component of the SWR1 complex; similar to YBR231C
Subunit of the ARP2/3 complex; similar to YBR234C
Vacuolar membrane cation-chloride cotransporter (CCC); similar to YBR235W
RNA helicase in the DEAD-box family; similar to YBR237W
Mitochondrial membrane protein; similar to YBR238C
Transcriptional regulator; similar to YBR239C
Transcriptional activator of thiamine biosynthetic genes; similar to YBR240C
transporter, member of the sugar porter family; similar to YBR241C
UDP-N-acetyl-glucosamine-1-P transferase; similar to YBR243C
Phospholipid hydroperoxide glutathione peroxidase; similar to YBR244W
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers; similar to YBR245C
Methylesterase performing penultimate step of diphthamide biosynthesis; similar to YBR246W
Protein associated with U3 and U14 snoRNAs; similar to YBR247C
Imidazole glycerol phosphate synthase; similar to YBR248C
3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase; similar to YBR249C
Mitochondrial ribosomal protein of the small subunit; similar to YBR251W
deoxyuridine triphosphate diphosphatase (dUTPase); similar to YBR252W
Subunit of the RNA polymerase II mediator complex; similar to YBR253W
Core component of transport protein particle (TRAPP) complexes I-III; similar to YBR254C
Subunit of both RNase MRP and nuclear RNase P; similar to YBR257W
Subunit of the COMPASS (Set1C) complex; similar to YBR258C
GTPase-activating protein (RhoGAP) for Rho3p and Rho4p; similar to YBR260C
AdoMet-dependent proline methyltransferase; similar to YBR261C
Component of the MICOS complex; similar to YBR262C
Mitochondrial serine hydroxymethyltransferase; similar to YBR263W
Rab family GTP-binding protein; similar to YBR264C
3-ketosphinganine reductase; similar to YBR265W
Cytoplasmic pre-60S factor; similar to YBR267W
Mitochondrial ribosomal protein of the large subunit; similar to YBR268W
Protein required for assembly of succinate dehydrogenase; similar to YBR269C
Subunit of TORC2 membrane-associated complex; similar to YBR270C
S-adenosylmethionine-dependent methyltransferase; similar to YBR271W
Proteasome-interacting protein; similar to YBR272C
UBX (ubiquitin regulatory X) domain-containing protein; similar to YBR273C
Serine/threonine kinase and DNA damage checkpoint effector; similar to YBR274W
Protein that binds to the Rap1p C-terminus; similar to YBR275C
Third-largest subunit of DNA polymerase II (DNA polymerase epsilon); similar to YBR278W
Component of the Paf1p complex involved in transcription elongation; similar to YBR279W
F-Box protein involved in proteasome-dependent degradation of Aah1p; similar to YBR280C
Component of glutamine amidotransferase (GATase II); similar to YBR281C
Mitochondrial ribosomal protein of the large subunit; similar to YBR282W
Subunit of the Ssh1 translocon complex; similar to YBR283C
metallo-dependent hydrolase superfamily protein; similar to YBR284W
Vacuolar aminopeptidase Y; similar to YBR286W
Mu3-like subunit of the clathrin associated protein complex (AP-3); similar to YBR288C
Subunit of the SWI/SNF chromatin remodeling complex; similar to YBR289W
Heavy metal ion homeostasis protein; similar to YBR290W
Mitochondrial inner membrane citrate transporter; similar to YBR291C
Permease of basic amino acids in the vacuolar membrane; similar to YBR293W
High affinity sulfate permease of the SulP anion transporter family; similar to YBR294W
Cadmium transporting P-type ATPase; similar to YBR295W
Plasma membrane Na+/Pi cotransporter; similar to YBR296C
MAL-activator protein; similar to YBR297W
Transcriptional activator of the basic leucine zipper (bZIP) family; similar to YPR199C
Arsenate reductase required for arsenate resistance; similar to YPR200C
Plasma membrane metalloid/H+ antiporter; similar to YPR201W