Severe acute respiratory syndrome coronavirus 2 isolate Wuhan-Hu-1, complete genome.
type: Entry
definition: Severe acute respiratory syndrome coronavirus 2 isolate Wuhan-Hu-1, complete genome.
sequence version: NC_045512.2
sequence date: 2020-07-18
sequence: sequence
division: VRL
label: NC_045512.2
type: RefSeq
SIO_000068: refseq
dblink: PRJNA485481
keyword: RefSeq
source: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
organism: Severe acute respiratory syndrome coronavirus 2
taxonomy: Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes; Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae; Betacoronavirus; Sarbecovirus.
reference: 1
references: 32015508
reference: 2
references: 15680415
reference: 3
references: 15630477
reference: 4
references: 10482585
reference: 5
reference: 6
comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The\nreference sequence is identical to MN908947.\nOn Jan 17, 2020 this sequence version replaced NC_045512.1.\nAnnotation was added using homology to SARSr-CoV NC_004718.3. ###\nFormerly called 'Wuhan seafood market pneumonia virus.' If you have\nquestions or suggestions, please email us at info@ncbi.nlm.nih.gov\nand include the accession number NC_045512.### Protein structures\ncan be found at\nhttps://www.ncbi.nlm.nih.gov/structure/?term=sars-cov-2.### Find\nall other Severe acute respiratory syndrome coronavirus 2\n(SARS-CoV-2) sequences at\nhttps://www.ncbi.nlm.nih.gov/genbank/sars-cov-2-seqs/\n\n##Assembly-Data-START##\nAssembly Method :: Megahit v. V1.1.3\nSequencing Technology :: Illumina\n##Assembly-Data-END##\nCOMPLETENESS: full length.

sequence
subclass of: SO_0000353
sequence length: 29903
topology: linear
so has quality: SO_0000987
location: 1..29903
location: region:1-29903:1
RO_0002162: 2697049

NC_045512
type: RefSeq
SIO_000068: refseq

PRJNA485481
type: BioProject
SIO_000068: bioproject

1
title: A new coronavirus associated with human respiratory disease in China
author: Wu, F.
author: Zhao, S.
author: Yu, B.
author: Chen, Y.M.
author: Wang, W.
author: Song, Z.G.
author: Hu, Y.
author: Tao, Z.W.
author: Tian, J.H.
author: Pei, Y.Y.
author: Yuan, M.L.
author: Zhang, Y.L.
author: Dai, F.H.
author: Liu, Y.
author: Wang, Q.M.
author: Zheng, J.J.
author: Xu, L.
author: Holmes, E.C.
author: Zhang, Y.Z.
journal: Nature
volume: 579
issue: 7798
pages: 265-269
year: 2020
pubmed: 32015508
comments: Erratum:[Nature. 2020 Apr;580(7803):E7. PMID: 32296181]

32015508
type: PubMed
SIO_000068: pubmed

2
title: Programmed ribosomal frameshifting in decoding the SARS-CoV genome
author: Baranov, P.V.
author: Henderson, C.M.
author: Anderson, C.B.
author: Gesteland, R.F.
author: Atkins, J.F.
author: Howard, M.T.
journal: Virology
volume: 332
issue: 2
pages: 498-510
year: 2005
pubmed: 15680415

15680415
type: PubMed
SIO_000068: pubmed

3
title: The structure of a rigorously conserved RNA element within the SARS virus genome
author: Robertson, M.P.
author: Igel, H.
author: Baertsch, R.
author: Haussler, D.
author: Ares, M. Jr.
author: Scott, W.G.
journal: PLoS Biol. 3 (1), e5 (2005)
pubmed: 15630477

15630477
type: PubMed
SIO_000068: pubmed

4
title: A phylogenetically conserved hairpin-type 3' untranslated region pseudoknot functions in coronavirus RNA replication
author: Williams, G.D.
author: Chang, R.Y.
author: Brian, D.A.
journal: J. Virol.
volume: 73
issue: 10
pages: 8349-8355
year: 1999
pubmed: 10482585

10482585
type: PubMed
SIO_000068: pubmed

5
title: Direct Submission
journal: Submitted (17-JAN-2020) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA

6
title: Direct Submission
author: Wu, F.
author: Zhao, S.
author: Yu, B.
author: Chen, Y.-M.
author: Wang, W.
author: Hu, Y.
author: Song, Z.-G.
author: Tao, Z.-W.
author: Tian, J.-H.
author: Pei, Y.-Y.
author: Yuan, M.L.
author: Zhang, Y.-L.
author: Dai, F.-H.
author: Liu, Y.
author: Wang, Q.-M.
author: Zheng, J.-J.
author: Xu, L.
author: Holmes, E.C.
author: Zhang, Y.-Z.
journal: Submitted (05-JAN-2020) Shanghai Public Health Clinical Center & School of Public Health, Fudan University, Shanghai, China

position:1:1
position: 1
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:29903:1
position: 29903
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

feature:1-29903:1:source
so part of: sequence
organism: Severe acute respiratory syndrome coronavirus 2
mol type: genomic RNA
isolate: Wuhan-Hu-1
host: Homo sapiens
country: China
collection date: Dec-2019

2697049
type: Taxonomy
SIO_000068: taxonomy

5'UTR
type: Five Prime UTR
subclass of: SO_0000204
RO_0002162: 2697049
so part of: sequence
location: 1..265
location: region:1-265:1
so has part: feature:1-265:1:region

position:265:1
position: 265
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:1-265:1:region

GU280_gp01
type: Gene
subclass of: SO_0000704
RO_0002162: 2697049
gene: ORF1ab
locus tag: GU280_gp01
so part of: sequence
location: 266..21555
location: region:266-21555:1
so has part: feature:266-21555:1:exon
subclass of: SO_0000010

43740578
type: Gene
SIO_000068: ncbigene

position:266:1
position: 266
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:21555:1
position: 21555
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:266-21555:1:exon

GU280_gp01
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 2697049
gene: ORF1ab
locus tag: GU280_gp01
ribosomal slippage: true
note: pp1ab; translated by -1 ribosomal frameshift
codon start: 1
product: ORF1ab polyprotein
translation: MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGVLPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRIRSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEAARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDDTVIEVQGYKSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALRKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPTTFHLDGEVITFDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATNK…
SIO_010081: GU280_gp01
subclass of: SO_0000673
so part of: GU280_gp01
location: join(266..13468,13468..21555)
location: region:266-21555:1
so has part: feature:266-13468:1:exon
so has part: feature:13468-21555:1:exon

YP_009724389.1
type: Protein
SIO_000068: ncbiprotein

urn:…
SIO_000300: 1
SIO_000628: feature:266-13468:1:exon

position:13468:1
position: 13468
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:13468-21555:1:exon

GU280_gp01
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 2697049
gene: ORF1ab
locus tag: GU280_gp01
product: leader protein
note: nsp1; produced by both pp1a and pp1ab
SIO_010081: GU280_gp01
subclass of: SO_0000673
so part of: GU280_gp01
location: 266..805
location: region:266-805:1
so has part: feature:266-805:1:exon

YP_009725297.1
type: Protein
SIO_000068: ncbiprotein

position:805:1
position: 805
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:266-805:1:exon

GU280_gp01
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 2697049
gene: ORF1ab
locus tag: GU280_gp01
product: nsp2
note: produced by both pp1a and pp1ab
SIO_010081: GU280_gp01
subclass of: SO_0000673
so part of: GU280_gp01
location: 806..2719
location: region:806-2719:1
so has part: feature:806-2719:1:exon

YP_009725298.1
type: Protein
SIO_000068: ncbiprotein

position:806:1
position: 806
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:2719:1
position: 2719
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:806-2719:1:exon

GU280_gp01
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 2697049
gene: ORF1ab
locus tag: GU280_gp01
product: nsp3
note: former nsp1; conserved domains are: N-terminal acidic (Ac), predicted phosphoesterase, papain-like proteinase, Y-domain, transmembrane domain 1 (TM1), adenosine diphosphate-ribose 1''-phosphatase (ADRP); produced by both pp1a and pp1ab
SIO_010081: GU280_gp01
subclass of: SO_0000673
so part of: GU280_gp01
location: 2720..8554
location: region:2720-8554:1
so has part: feature:2720-8554:1:exon

YP_009725299.1
type: Protein
SIO_000068: ncbiprotein

position:2720:1
position: 2720
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:8554:1
position: 8554
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:2720-8554:1:exon

GU280_gp01
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 2697049
gene: ORF1ab
locus tag: GU280_gp01
product: nsp4
note: nsp4B_TM; contains transmembrane domain 2 (TM2); produced by both pp1a and pp1ab
SIO_010081: GU280_gp01
subclass of: SO_0000673
so part of: GU280_gp01
location: 8555..10054
location: region:8555-10054:1
so has part: feature:8555-10054:1:exon

YP_009725300.1
type: Protein
SIO_000068: ncbiprotein

position:8555:1
position: 8555
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:10054:1
position: 10054
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:8555-10054:1:exon

GU280_gp01
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 2697049
gene: ORF1ab
locus tag: GU280_gp01
product: 3C-like proteinase
note: nsp5A_3CLpro and nsp5B_3CLpro; main proteinase (Mpro); mediates cleavages downstream of nsp4. 3D structure of the SARSr-CoV homolog has been determined (Yang et al., 2003); produced by both pp1a and pp1ab
SIO_010081: GU280_gp01
subclass of: SO_0000673
so part of: GU280_gp01
location: 10055..10972
location: region:10055-10972:1
so has part: feature:10055-10972:1:exon

YP_009725301.1
type: Protein
SIO_000068: ncbiprotein

position:10055:1
position: 10055
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:10972:1
position: 10972
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:10055-10972:1:exon

GU280_gp01
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 2697049
gene: ORF1ab
locus tag: GU280_gp01
product: nsp6
note: nsp6_TM; putative transmembrane domain; produced by both pp1a and pp1ab
SIO_010081: GU280_gp01
subclass of: SO_0000673
so part of: GU280_gp01
location: 10973..11842
location: region:10973-11842:1
so has part: feature:10973-11842:1:exon

YP_009725302.1
type: Protein
SIO_000068: ncbiprotein

position:10973:1
position: 10973
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:11842:1
position: 11842
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:10973-11842:1:exon

GU280_gp01
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 2697049
gene: ORF1ab
locus tag: GU280_gp01
product: nsp7
note: produced by both pp1a and pp1ab
SIO_010081: GU280_gp01
subclass of: SO_0000673
so part of: GU280_gp01
location: 11843..12091
location: region:11843-12091:1
so has part: feature:11843-12091:1:exon

YP_009725303.1
type: Protein
SIO_000068: ncbiprotein

position:11843:1
position: 11843
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:12091:1
position: 12091
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:11843-12091:1:exon

GU280_gp01
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 2697049
gene: ORF1ab
locus tag: GU280_gp01
product: nsp8
note: produced by both pp1a and pp1ab
SIO_010081: GU280_gp01
subclass of: SO_0000673
so part of: GU280_gp01
location: 12092..12685
location: region:12092-12685:1
so has part: feature:12092-12685:1:exon

YP_009725304.1
type: Protein
SIO_000068: ncbiprotein

position:12092:1
position: 12092
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:12685:1
position: 12685
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:12092-12685:1:exon

GU280_gp01
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 2697049
gene: ORF1ab
locus tag: GU280_gp01
product: nsp9
note: ssRNA-binding protein; produced by both pp1a and pp1ab
SIO_010081: GU280_gp01
subclass of: SO_0000673
so part of: GU280_gp01
location: 12686..13024
location: region:12686-13024:1
so has part: feature:12686-13024:1:exon

YP_009725305.1
type: Protein
SIO_000068: ncbiprotein

position:12686:1
position: 12686
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:13024:1
position: 13024
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:12686-13024:1:exon

GU280_gp01
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 2697049
gene: ORF1ab
locus tag: GU280_gp01
product: nsp10
note: nsp10_CysHis; formerly known as growth-factor-like protein (GFL); produced by both pp1a and pp1ab
SIO_010081: GU280_gp01
subclass of: SO_0000673
so part of: GU280_gp01
location: 13025..13441
location: region:13025-13441:1
so has part: feature:13025-13441:1:exon

YP_009725306.1
type: Protein
SIO_000068: ncbiprotein

position:13025:1
position: 13025
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:13441:1
position: 13441
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:13025-13441:1:exon

GU280_gp01
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 2697049
gene: ORF1ab
locus tag: GU280_gp01
product: RNA-dependent RNA polymerase
note: nsp12; NiRAN and RdRp; produced by pp1ab only
SIO_010081: GU280_gp01
subclass of: SO_0000673
so part of: GU280_gp01
location: join(13442..13468,13468..16236)
location: region:13442-16236:1
so has part: feature:13442-13468:1:exon
so has part: feature:13468-16236:1:exon

YP_009725307.1
type: Protein
SIO_000068: ncbiprotein

position:13442:1
position: 13442
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:16236:1
position: 16236
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:13442-13468:1:exon

urn:…
SIO_000300: 2
SIO_000628: feature:13468-16236:1:exon

GU280_gp01
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 2697049
gene: ORF1ab
locus tag: GU280_gp01
product: helicase
note: nsp13_ZBD, nsp13_TB, and nsp_HEL1core; zinc-binding domain (ZD), NTPase/helicase domain (HEL), RNA 5'-triphosphatase; produced by pp1ab only
SIO_010081: GU280_gp01
subclass of: SO_0000673
so part of: GU280_gp01
location: 16237..18039
location: region:16237-18039:1
so has part: feature:16237-18039:1:exon

YP_009725308.1
type: Protein
SIO_000068: ncbiprotein

position:16237:1
position: 16237
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:18039:1
position: 18039
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:16237-18039:1:exon

GU280_gp01
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 2697049
gene: ORF1ab
locus tag: GU280_gp01
product: 3'-to-5' exonuclease
note: nsp14A2_ExoN and nsp14B_NMT; produced by pp1ab only
SIO_010081: GU280_gp01
subclass of: SO_0000673
so part of: GU280_gp01
location: 18040..19620
location: region:18040-19620:1
so has part: feature:18040-19620:1:exon

YP_009725309.1
type: Protein
SIO_000068: ncbiprotein

position:18040:1
position: 18040
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:19620:1
position: 19620
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:18040-19620:1:exon

GU280_gp01
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 2697049
gene: ORF1ab
locus tag: GU280_gp01
product: endoRNAse
note: nsp15-A1 and nsp15B-NendoU; produced by pp1ab only
SIO_010081: GU280_gp01
subclass of: SO_0000673
so part of: GU280_gp01
location: 19621..20658
location: region:19621-20658:1
so has part: feature:19621-20658:1:exon

YP_009725310.1
type: Protein
SIO_000068: ncbiprotein

position:19621:1
position: 19621
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:20658:1
position: 20658
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:19621-20658:1:exon

GU280_gp01
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 2697049
gene: ORF1ab
locus tag: GU280_gp01
product: 2'-O-ribose methyltransferase
note: nsp16_OMT; 2'-o-MT; produced by pp1ab only
SIO_010081: GU280_gp01
subclass of: SO_0000673
so part of: GU280_gp01
location: 20659..21552
location: region:20659-21552:1
so has part: feature:20659-21552:1:exon

YP_009725311.1
type: Protein
SIO_000068: ncbiprotein

position:20659:1
position: 20659
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:21552:1
position: 21552
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:20659-21552:1:exon

GU280_gp01
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 2697049
gene: ORF1ab
locus tag: GU280_gp01
note: pp1a
codon start: 1
product: ORF1a polyprotein
translation: MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGVLPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRIRSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEAARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDDTVIEVQGYKSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALRKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPTTFHLDGEVITFDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATNK…
SIO_010081: GU280_gp01
subclass of: SO_0000673
so part of: GU280_gp01
location: 266..13483
location: region:266-13483:1
so has part: feature:266-13483:1:exon

YP_009725295.1
type: Protein
SIO_000068: ncbiprotein

position:13483:1
position: 13483
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:266-13483:1:exon

GU280_gp01
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 2697049
gene: ORF1ab
locus tag: GU280_gp01
product: leader protein
note: nsp1; produced by both pp1a and pp1ab
SIO_010081: GU280_gp01
subclass of: SO_0000673
so part of: GU280_gp01
location: 266..805
location: region:266-805:1
so has part: feature:266-805:1:exon

YP_009742608.1
type: Protein
SIO_000068: ncbiprotein

urn:…
SIO_000300: 1
SIO_000628: feature:266-805:1:exon

GU280_gp01
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 2697049
gene: ORF1ab
locus tag: GU280_gp01
product: nsp2
note: produced by both pp1a and pp1ab
SIO_010081: GU280_gp01
subclass of: SO_0000673
so part of: GU280_gp01
location: 806..2719
location: region:806-2719:1
so has part: feature:806-2719:1:exon

YP_009742609.1
type: Protein
SIO_000068: ncbiprotein

urn:…
SIO_000300: 1
SIO_000628: feature:806-2719:1:exon

GU280_gp01
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 2697049
gene: ORF1ab
locus tag: GU280_gp01
product: nsp3
note: former nsp1; conserved domains are: N-terminal acidic (Ac), predicted phosphoesterase, papain-like proteinase, Y-domain, transmembrane domain 1 (TM1), adenosine diphosphate-ribose 1''-phosphatase (ADRP); produced by both pp1a and pp1ab
SIO_010081: GU280_gp01
subclass of: SO_0000673
so part of: GU280_gp01
location: 2720..8554
location: region:2720-8554:1
so has part: feature:2720-8554:1:exon

YP_009742610.1
type: Protein
SIO_000068: ncbiprotein

urn:…
SIO_000300: 1
SIO_000628: feature:2720-8554:1:exon

GU280_gp01
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 2697049
gene: ORF1ab
locus tag: GU280_gp01
product: nsp4
note: nsp4B_TM; contains transmembrane domain 2 (TM2); produced by both pp1a and pp1ab
SIO_010081: GU280_gp01
subclass of: SO_0000673
so part of: GU280_gp01
location: 8555..10054
location: region:8555-10054:1
so has part: feature:8555-10054:1:exon

YP_009742611.1
type: Protein
SIO_000068: ncbiprotein

urn:…
SIO_000300: 1
SIO_000628: feature:8555-10054:1:exon

GU280_gp01
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 2697049
gene: ORF1ab
locus tag: GU280_gp01
product: 3C-like proteinase
note: nsp5A_3CLpro and nsp5B_3CLpro; main proteinase (Mpro); mediates cleavages downstream of nsp4. 3D structure of the SARSr-CoV homolog has been determined (Yang et al., 2003); produced by both pp1a and pp1ab
SIO_010081: GU280_gp01
subclass of: SO_0000673
so part of: GU280_gp01
location: 10055..10972
location: region:10055-10972:1
so has part: feature:10055-10972:1:exon

YP_009742612.1
type: Protein
SIO_000068: ncbiprotein

urn:…
SIO_000300: 1
SIO_000628: feature:10055-10972:1:exon

GU280_gp01
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 2697049
gene: ORF1ab
locus tag: GU280_gp01
product: nsp6
note: nsp6_TM; putative transmembrane domain; produced by both pp1a and pp1ab
SIO_010081: GU280_gp01
subclass of: SO_0000673
so part of: GU280_gp01
location: 10973..11842
location: region:10973-11842:1
so has part: feature:10973-11842:1:exon

YP_009742613.1
type: Protein
SIO_000068: ncbiprotein

urn:…
SIO_000300: 1
SIO_000628: feature:10973-11842:1:exon

GU280_gp01
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 2697049
gene: ORF1ab
locus tag: GU280_gp01
product: nsp7
note: produced by both pp1a and pp1ab
SIO_010081: GU280_gp01
subclass of: SO_0000673
so part of: GU280_gp01
location: 11843..12091
location: region:11843-12091:1
so has part: feature:11843-12091:1:exon

YP_009742614.1
type: Protein
SIO_000068: ncbiprotein

urn:…
SIO_000300: 1
SIO_000628: feature:11843-12091:1:exon

GU280_gp01
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 2697049
gene: ORF1ab
locus tag: GU280_gp01
product: nsp8
note: produced by both pp1a and pp1ab
SIO_010081: GU280_gp01
subclass of: SO_0000673
so part of: GU280_gp01
location: 12092..12685
location: region:12092-12685:1
so has part: feature:12092-12685:1:exon

YP_009742615.1
type: Protein
SIO_000068: ncbiprotein

urn:…
SIO_000300: 1
SIO_000628: feature:12092-12685:1:exon

GU280_gp01
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 2697049
gene: ORF1ab
locus tag: GU280_gp01
product: nsp9
note: ssRNA-binding protein; produced by both pp1a and pp1ab
SIO_010081: GU280_gp01
subclass of: SO_0000673
so part of: GU280_gp01
location: 12686..13024
location: region:12686-13024:1
so has part: feature:12686-13024:1:exon

YP_009742616.1
type: Protein
SIO_000068: ncbiprotein

urn:…
SIO_000300: 1
SIO_000628: feature:12686-13024:1:exon

GU280_gp01
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 2697049
gene: ORF1ab
locus tag: GU280_gp01
product: nsp10
note: nsp10_CysHis; formerly known as growth-factor-like protein (GFL); produced by both pp1a and pp1ab
SIO_010081: GU280_gp01
subclass of: SO_0000673
so part of: GU280_gp01
location: 13025..13441
location: region:13025-13441:1
so has part: feature:13025-13441:1:exon

YP_009742617.1
type: Protein
SIO_000068: ncbiprotein

urn:…
SIO_000300: 1
SIO_000628: feature:13025-13441:1:exon

GU280_gp01
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 2697049
gene: ORF1ab
locus tag: GU280_gp01
product: nsp11
note: produced by pp1a only
SIO_010081: GU280_gp01
subclass of: SO_0000673
so part of: GU280_gp01
location: 13442..13480
location: region:13442-13480:1
so has part: feature:13442-13480:1:exon

YP_009725312.1
type: Protein
SIO_000068: ncbiprotein

position:13480:1
position: 13480
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:13442-13480:1:exon

GU280_gp01
type: Stem Loop
subclass of: SO_0000313
RO_0002162: 2697049
gene: ORF1ab
locus tag: GU280_gp01
inference: COORDINATES: profile:Rfam-release-14.1:RF00507,Infernal:1.1.2
function: Coronavirus frameshifting stimulation element stem-loop 1
SIO_010081: GU280_gp01
subclass of: SO_0000673
so part of: GU280_gp01
location: 13476..13503
location: region:13476-13503:1
so has part: feature:13476-13503:1:exon

position:13476:1
position: 13476
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:13503:1
position: 13503
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:13476-13503:1:exon

GU280_gp01
type: Stem Loop
subclass of: SO_0000313
RO_0002162: 2697049
gene: ORF1ab
locus tag: GU280_gp01
inference: COORDINATES: profile:Rfam-release-14.1:RF00507,Infernal:1.1.2
function: Coronavirus frameshifting stimulation element stem-loop 2
SIO_010081: GU280_gp01
subclass of: SO_0000673
so part of: GU280_gp01
location: 13488..13542
location: region:13488-13542:1
so has part: feature:13488-13542:1:exon

position:13488:1
position: 13488
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:13542:1
position: 13542
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:13488-13542:1:exon

GU280_gp02
type: Gene
subclass of: SO_0000704
RO_0002162: 2697049
alternative label: spike glycoprotein
gene: S
locus tag: GU280_gp02
gene synonym: spike glycoprotein
so part of: sequence
location: 21563..25384
location: region:21563-25384:1
so has part: feature:21563-25384:1:exon
subclass of: SO_0000010

43740568
type: Gene
SIO_000068: ncbigene

position:21563:1
position: 21563
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:25384:1
position: 25384
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:21563-25384:1:exon

GU280_gp02
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 2697049
alternative label: spike glycoprotein
gene: S
locus tag: GU280_gp02
gene synonym: spike glycoprotein
note: structural protein; spike protein
codon start: 1
product: surface glycoprotein
translation: MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGCCSCGSCCKFDEDDSEPVLKGVKLHYT
SIO_010081: GU280_gp02
subclass of: SO_0000673
so part of: GU280_gp02
location: 21563..25384
location: region:21563-25384:1
so has part: feature:21563-25384:1:exon

YP_009724390.1
type: Protein
SIO_000068: ncbiprotein

urn:…
SIO_000300: 1
SIO_000628: feature:21563-25384:1:exon

GU280_gp03
type: Gene
subclass of: SO_0000704
RO_0002162: 2697049
gene: ORF3a
locus tag: GU280_gp03
so part of: sequence
location: 25393..26220
location: region:25393-26220:1
so has part: feature:25393-26220:1:exon
subclass of: SO_0000010

43740569
type: Gene
SIO_000068: ncbigene

position:25393:1
position: 25393
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:26220:1
position: 26220
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:25393-26220:1:exon

GU280_gp03
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 2697049
gene: ORF3a
locus tag: GU280_gp03
codon start: 1
product: ORF3a protein
translation: MDLFMRIFTIGTVTLKQGEIKDATPSDFVRATATIPIQASLPFGWLIVGVALLAVFQSASKIITLKKRWQLALSKGVHFVCNLLLLFVTVYSHLLLVAAGLEAPFLYLYALVYFLQSINFVRIIMRLWLCWKCRSKNPLLYDANYFLCWHTNCYDYCIPYNSVTSSIVITSGDGTTSPISEHDYQIGGYTEKWESGVKDCVVLHSYFTSDYYQLYSTQLSTDTGVEHVTFFIYNKIVDEPEEHVQIHTIDGSSGVVNPVMEPIYDEPTTTTSVPL
SIO_010081: GU280_gp03
subclass of: SO_0000673
so part of: GU280_gp03
location: 25393..26220
location: region:25393-26220:1
so has part: feature:25393-26220:1:exon

YP_009724391.1
type: Protein
SIO_000068: ncbiprotein

urn:…
SIO_000300: 1
SIO_000628: feature:25393-26220:1:exon

GU280_gp04
type: Gene
subclass of: SO_0000704
RO_0002162: 2697049
gene: E
locus tag: GU280_gp04
so part of: sequence
location: 26245..26472
location: region:26245-26472:1
so has part: feature:26245-26472:1:exon
subclass of: SO_0000010

43740570
type: Gene
SIO_000068: ncbigene

position:26245:1
position: 26245
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:26472:1
position: 26472
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:26245-26472:1:exon

GU280_gp04
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 2697049
gene: E
locus tag: GU280_gp04
note: ORF4; structural protein; E protein
codon start: 1
product: envelope protein
translation: MYSFVSEETGTLIVNSVLLFLAFVVFLLVTLAILTALRLCAYCCNIVNVSLVKPSFYVYSRVKNLNSSRVPDLLV
SIO_010081: GU280_gp04
subclass of: SO_0000673
so part of: GU280_gp04
location: 26245..26472
location: region:26245-26472:1
so has part: feature:26245-26472:1:exon

YP_009724392.1
type: Protein
SIO_000068: ncbiprotein

urn:…
SIO_000300: 1
SIO_000628: feature:26245-26472:1:exon

GU280_gp05
type: Gene
subclass of: SO_0000704
RO_0002162: 2697049
gene: M
locus tag: GU280_gp05
so part of: sequence
location: 26523..27191
location: region:26523-27191:1
so has part: feature:26523-27191:1:exon
subclass of: SO_0000010

43740571
type: Gene
SIO_000068: ncbigene

position:26523:1
position: 26523
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:27191:1
position: 27191
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:26523-27191:1:exon

GU280_gp05
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 2697049
gene: M
locus tag: GU280_gp05
note: ORF5; structural protein
codon start: 1
product: membrane glycoprotein
translation: MADSNGTITVEELKKLLEQWNLVIGFLFLTWICLLQFAYANRNRFLYIIKLIFLWLLWPVTLACFVLAAVYRINWITGGIAIAMACLVGLMWLSYFIASFRLFARTRSMWSFNPETNILLNVPLHGTILTRPLLESELVIGAVILRGHLRIAGHHLGRCDIKDLPKEITVATSRTLSYYKLGASQRVAGDSGFAAYSRYRIGNYKLNTDHSSSSDNIALLVQ
SIO_010081: GU280_gp05
subclass of: SO_0000673
so part of: GU280_gp05
location: 26523..27191
location: region:26523-27191:1
so has part: feature:26523-27191:1:exon

YP_009724393.1
type: Protein
SIO_000068: ncbiprotein

urn:…
SIO_000300: 1
SIO_000628: feature:26523-27191:1:exon

GU280_gp06
type: Gene
subclass of: SO_0000704
RO_0002162: 2697049
gene: ORF6
locus tag: GU280_gp06
so part of: sequence
location: 27202..27387
location: region:27202-27387:1
so has part: feature:27202-27387:1:exon
subclass of: SO_0000010

43740572
type: Gene
SIO_000068: ncbigene

position:27202:1
position: 27202
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:27387:1
position: 27387
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:27202-27387:1:exon

GU280_gp06
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 2697049
gene: ORF6
locus tag: GU280_gp06
codon start: 1
product: ORF6 protein
translation: MFHLVDFQVTIAEILLIIMRTFKVSIWNLDYIINLIIKNLSKSLTENKYSQLDEEQPMEID
SIO_010081: GU280_gp06
subclass of: SO_0000673
so part of: GU280_gp06
location: 27202..27387
location: region:27202-27387:1
so has part: feature:27202-27387:1:exon

YP_009724394.1
type: Protein
SIO_000068: ncbiprotein

urn:…
SIO_000300: 1
SIO_000628: feature:27202-27387:1:exon

GU280_gp07
type: Gene
subclass of: SO_0000704
RO_0002162: 2697049
gene: ORF7a
locus tag: GU280_gp07
so part of: sequence
location: 27394..27759
location: region:27394-27759:1
so has part: feature:27394-27759:1:exon
subclass of: SO_0000010

43740573
type: Gene
SIO_000068: ncbigene

position:27394:1
position: 27394
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:27759:1
position: 27759
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:27394-27759:1:exon

GU280_gp07
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 2697049
gene: ORF7a
locus tag: GU280_gp07
codon start: 1
product: ORF7a protein
translation: MKIILFLALITLATCELYHYQECVRGTTVLLKEPCSSGTYEGNSPFHPLADNKFALTCFSTQFAFACPDGVKHVYQLRARSVSPKLFIRQEEVQELYSPIFLIVAAIVFITLCFTLKRKTE
SIO_010081: GU280_gp07
subclass of: SO_0000673
so part of: GU280_gp07
location: 27394..27759
location: region:27394-27759:1
so has part: feature:27394-27759:1:exon

YP_009724395.1
type: Protein
SIO_000068: ncbiprotein

urn:…
SIO_000300: 1
SIO_000628: feature:27394-27759:1:exon

GU280_gp08
type: Gene
subclass of: SO_0000704
RO_0002162: 2697049
gene: ORF7b
locus tag: GU280_gp08
so part of: sequence
location: 27756..27887
location: region:27756-27887:1
so has part: feature:27756-27887:1:exon
subclass of: SO_0000010

43740574
type: Gene
SIO_000068: ncbigene

position:27756:1
position: 27756
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:27887:1
position: 27887
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:27756-27887:1:exon

GU280_gp08
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 2697049
gene: ORF7b
locus tag: GU280_gp08
codon start: 1
product: ORF7b
translation: MIELSLIDFYLCFLAFLLFLVLIMLIIFWFSLELQDHNETCHA
SIO_010081: GU280_gp08
subclass of: SO_0000673
so part of: GU280_gp08
location: 27756..27887
location: region:27756-27887:1
so has part: feature:27756-27887:1:exon

YP_009725318.1
type: Protein
SIO_000068: ncbiprotein

urn:…
SIO_000300: 1
SIO_000628: feature:27756-27887:1:exon

GU280_gp09
type: Gene
subclass of: SO_0000704
RO_0002162: 2697049
gene: ORF8
locus tag: GU280_gp09
so part of: sequence
location: 27894..28259
location: region:27894-28259:1
so has part: feature:27894-28259:1:exon
subclass of: SO_0000010

43740577
type: Gene
SIO_000068: ncbigene

position:27894:1
position: 27894
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:28259:1
position: 28259
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:27894-28259:1:exon

GU280_gp09
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 2697049
gene: ORF8
locus tag: GU280_gp09
codon start: 1
product: ORF8 protein
translation: MKFLVFLGIITTVAAFHQECSLQSCTQHQPYVVDDPCPIHFYSKWYIRVGARKSAPLIELCVDEAGSKSPIQYIDIGNYTVSCLPFTINCQEPKLGSLVVRCSFYEDFLEYHDVRVVLDFI
SIO_010081: GU280_gp09
subclass of: SO_0000673
so part of: GU280_gp09
location: 27894..28259
location: region:27894-28259:1
so has part: feature:27894-28259:1:exon

YP_009724396.1
type: Protein
SIO_000068: ncbiprotein

urn:…
SIO_000300: 1
SIO_000628: feature:27894-28259:1:exon

GU280_gp10
type: Gene
subclass of: SO_0000704
RO_0002162: 2697049
gene: N
locus tag: GU280_gp10
so part of: sequence
location: 28274..29533
location: region:28274-29533:1
so has part: feature:28274-29533:1:exon
subclass of: SO_0000010

43740575
type: Gene
SIO_000068: ncbigene

position:28274:1
position: 28274
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:29533:1
position: 29533
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:28274-29533:1:exon

GU280_gp10
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 2697049
gene: N
locus tag: GU280_gp10
note: ORF9; structural protein
codon start: 1
product: nucleocapsid phosphoprotein
translation: MSDNGPQNQRNAPRITFGGPSDSTGSNQNGERSGARSKQRRPQGLPNNTASWFTALTQHGKEDLKFPRGQGVPINTNSSPDDQIGYYRRATRRIRGGDGKMKDLSPRWYFYYLGTGPEAGLPYGANKDGIIWVATEGALNTPKDHIGTRNPANNAAIVLQLPQGTTLPKGFYAEGSRGGSQASSRSSSRSRNSSRNSTPGSSRGTSPARMAGNGGDAALALLLLDRLNQLESKMSGKGQQQQGQTVTKKSAAEASKKPRQKRTATKAYNVTQAFGRRGPEQTQGNFGDQELIRQGTDYKHWPQIAQFAPSASAFFGMSRIGMEVTPSGTWLTYTGAIKLDDKDPNFKDQVILLNKHIDAYKTFPPTEPKKDKKKKADETQALPQRQKKQQTVTLLPAADLDDFSKQLQQSMSSADSTQA
SIO_010081: GU280_gp10
subclass of: SO_0000673
so part of: GU280_gp10
location: 28274..29533
location: region:28274-29533:1
so has part: feature:28274-29533:1:exon

YP_009724397.2
type: Protein
SIO_000068: ncbiprotein

urn:…
SIO_000300: 1
SIO_000628: feature:28274-29533:1:exon

GU280_gp11
type: Gene
subclass of: SO_0000704
RO_0002162: 2697049
gene: ORF10
locus tag: GU280_gp11
so part of: sequence
location: 29558..29674
location: region:29558-29674:1
so has part: feature:29558-29674:1:exon
subclass of: SO_0000010

43740576
type: Gene
SIO_000068: ncbigene

position:29558:1
position: 29558
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:29674:1
position: 29674
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:29558-29674:1:exon

GU280_gp11
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 2697049
gene: ORF10
locus tag: GU280_gp11
codon start: 1
product: ORF10 protein
translation: MGYINVFAFPFTIYSLLLCRMNSRNYIAQVDVVNFNLT
SIO_010081: GU280_gp11
subclass of: SO_0000673
so part of: GU280_gp11
location: 29558..29674
location: region:29558-29674:1
so has part: feature:29558-29674:1:exon

YP_009725255.1
type: Protein
SIO_000068: ncbiprotein

urn:…
SIO_000300: 1
SIO_000628: feature:29558-29674:1:exon

GU280_gp11
type: Stem Loop
subclass of: SO_0000313
RO_0002162: 2697049
gene: ORF10
locus tag: GU280_gp11
inference: COORDINATES: profile::Rfam-release-14.1:RF00165,Infernal:1.1.2
function: Coronavirus 3' UTR pseudoknot stem-loop 1
SIO_010081: GU280_gp11
subclass of: SO_0000673
so part of: GU280_gp11
location: 29609..29644
location: region:29609-29644:1
so has part: feature:29609-29644:1:exon

position:29609:1
position: 29609
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:29644:1
position: 29644
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:29609-29644:1:exon

GU280_gp11
type: Stem Loop
subclass of: SO_0000313
RO_0002162: 2697049
gene: ORF10
locus tag: GU280_gp11
inference: COORDINATES: profile::Rfam-release-14.1:RF00165,Infernal:1.1.2
function: Coronavirus 3' UTR pseudoknot stem-loop 2
SIO_010081: GU280_gp11
subclass of: SO_0000673
so part of: GU280_gp11
location: 29629..29657
location: region:29629-29657:1
so has part: feature:29629-29657:1:exon

position:29629:1
position: 29629
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:29657:1
position: 29657
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:29629-29657:1:exon

3'UTR
type: Three Prime UTR
subclass of: SO_0000205
RO_0002162: 2697049
so part of: sequence
location: 29675..29903
location: region:29675-29903:1
so has part: feature:29675-29903:1:region

position:29675:1
position: 29675
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:29675-29903:1:region

stem_loop
type: Stem Loop
subclass of: SO_0000313
RO_0002162: 2697049
inference: COORDINATES: profile:Rfam-release-14.1:RF00164,Infernal:1.1.2
note: basepair exception: alignment to the Rfam model implies coordinates 29740:29758 form a noncanonical C:T basepair, but the homologous positions form a highly conserved C:G basepair in other viruses, including SARS (NC_004718.3)
function: Coronavirus 3' stem-loop II-like motif (s2m)
so part of: sequence
location: 29728..29768
location: region:29728-29768:1
so has part: feature:29728-29768:1:region

position:29728:1
position: 29728
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:29768:1
position: 29768
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:29728-29768:1:region