Psychrobacter arcticus 273-4, complete sequence.
Bacteria; Proteobacteria; Gammaproteobacteria; Moraxellales; Moraxellaceae; Psychrobacter.
The genome sequence of Psychrobacter arcticus 273-4, a psychroactive Siberian permafrost bacterium, reveals mechanisms for adaptation to low-temperature growth
Complete sequence of Psychrobacter arcticum 273-4
Submitted (23-JUN-2005) US DOE Joint Genome Institute, 2800 Mitchell Drive B100, Walnut Creek, CA 94598-1698, USA
REFSEQ INFORMATION: The reference sequence is identical to\nCP000082.1.\nURL -- http://www.jgi.doe.gov\nContacts: Paul Richardson (microbes@cuba.jgi-psf.org)\nHector L. Ayala-del-Rio (hlayala@hpcf.upr.edu)\nFinished microbial genomes have been curated to close all gaps with\ngreater than 98% coverage of at least two independent clones. Each\nbase pair has a minimum q (quality) value of 30 and the total error\nrate is less than one per 50000.\nThe annotation was added by the NCBI Prokaryotic Genome Annotation\nPipeline (PGAP). Information about PGAP can be found here:\nhttps://www.ncbi.nlm.nih.gov/genome/annotation_prok/\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: NCBI RefSeq\nAnnotation Date :: 11/04/2022 00:53:50\nAnnotation Pipeline :: NCBI Prokaryotic Genome\n Annotation Pipeline (PGAP)\nAnnotation Method :: Best-placed reference protein\n set; GeneMarkS-2+\nAnnotation Software revision :: 6.3\nFeatures Annotated :: Gene; CDS; rRNA; tRNA; ncRNA;\n repeat_region\nGenes (total) :: 2,262\nCDSs (total) :: 2,198\nGenes (coding) :: 2,137\nCDSs (with protein) :: 2,137\nGenes (RNA) :: 64\nrRNAs :: 4, 4, 4 (5S, 16S, 23S)\ncomplete rRNAs :: 4, 4, 4 (5S, 16S, 23S)\ntRNAs :: 48\nncRNAs :: 4\nPseudo Genes (total) :: 61\nCDSs (without protein) :: 61\nPseudo Genes (ambiguous residues) :: 0 of 61\nPseudo Genes (frameshifted) :: 14 of 61\nPseudo Genes (incomplete) :: 56 of 61\nPseudo Genes (internal stop) :: 9 of 61\nPseudo Genes (multiple problems) :: 14 of 61\n##Genome-Annotation-Data-END##\nCOMPLETENESS: full length.
initiation and regulation of chromosomal replication
COORDINATES: similar to AA sequence:RefSeq:WP_011279314.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0003677 - DNA binding [Evidence IEA]; GO:0003688 - DNA replication origin binding [Evidence IEA]
GO:0006270 - DNA replication initiation [Evidence IEA]; GO:0006275 - regulation of DNA replication [Evidence IEA]
Derived by automated computational analysis using gene prediction method: Protein Homology.
chromosomal replication initiator protein DnaA
DNA polymerase III holoenzyme is responsible for most of the replicative synthesis in bacteria. The beta subunit is required for initiation of replication from an RNA primer.
COORDINATES: similar to AA sequence:RefSeq:WP_011512380.1
GO:0009360 - DNA polymerase III complex [Evidence IEA]
GO:0003887 - DNA-directed DNA polymerase activity [Evidence IEA]
GO:0006260 - DNA replication [Evidence IEA]
All proteins in this family for which functions are known are DNA binding proteins that assist the filamentation of RecA onto DNA for the initiation of recombination or recombinational repair.
COORDINATES: similar to AA sequence:RefSeq:WP_011512381.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0003697 - single-stranded DNA binding [Evidence IEA]
GO:0006310 - DNA recombination [Evidence IEA]; GO:0006281 - DNA repair [Evidence IEA]; GO:0006260 - DNA replication [Evidence IEA]; GO:0009432 - SOS response [Evidence IEA]
All proteins in this family for which functions are known are DNA-binding proteins that assist the filamentation of RecA onto DNA for the initiation of recombination or recombinational repair; Derived by automated computational analysis using gene prediction method: Protein Homology.
DNA gyrase catalyses the interconversion of topological isomers of DNA and play a key role in DNA metabolism.
COORDINATES: similar to AA sequence:RefSeq:WP_011512382.1
GO:0009330 - DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex [Evidence IEA]
GO:0003918 - DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [Evidence IEA]
GO:0006265 - DNA topological change [Evidence IEA]
DNA topoisomerase (ATP-hydrolyzing) subunit B
COORDINATES: similar to AA sequence:RefSeq:WP_011279318.1
manganese efflux pump MntP family protein
COORDINATES: protein motif:HMM:NF033516.0
GO:0004803 - transposase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011280724.1
helix-turn-helix domain-containing protein
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate for regulatory purposes
COORDINATES: similar to AA sequence:RefSeq:WP_011279321.1
GO:0008988 - rRNA (adenine-N6-)-methyltransferase activity [Evidence IEA]
GO:0006364 - rRNA processing [Evidence IEA]
23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF
COORDINATES: similar to AA sequence:RefSeq:WP_010197571.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0003922 - GMP synthase (glutamine-hydrolyzing) activity [Evidence IEA]; GO:0016462 - pyrophosphatase activity [Evidence IEA]
GO:0006177 - GMP biosynthetic process [Evidence IEA]
COORDINATES: ab initio prediction:GeneMarkS-2+
Derived by automated computational analysis using gene prediction method: GeneMarkS-2+.
COORDINATES: similar to AA sequence:RefSeq:WP_020442420.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512395.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512396.1
oxidoreductase activity :Members of this family catalyse the denitrification of a number of nitroalkanes using either FAD or FMN as a cofactor.
COORDINATES: similar to AA sequence:RefSeq:WP_011279327.1
COORDINATES: similar to AA sequence:RefSeq:WP_076612080.1
programmed frameshift; Derived by automated computational analysis using gene prediction method: Protein Homology.
IS3-like element ISPar1 family transposase
COORDINATES: protein motif:HMM:NF024867.2
COORDINATES: similar to AA sequence:RefSeq:WP_011512403.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442428.1
COORDINATES: similar to AA sequence:RefSeq:WP_010197635.1
COORDINATES: similar to AA sequence:RefSeq:WP_003662138.1
GO:0009982 - pseudouridine synthase activity [Evidence IEA]
GO:0001522 - pseudouridine synthesis [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020442432.1
thioredoxin fold domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_010197648.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512410.1
GO:0005515 - protein binding [Evidence IEA]
GO:0006457 - protein folding [Evidence IEA]; GO:0009408 - response to heat [Evidence IEA]
Diaminopimelate biosynthesis, Lysine biosynthesis via diaminopimellate
COORDINATES: similar to AA sequence:RefSeq:WP_011279341.1
GO:0008839 - 4-hydroxy-tetrahydrodipicolinate reductase [Evidence IEA]
GO:0009089 - lysine biosynthetic process via diaminopimelate [Evidence IEA]
4-hydroxy-tetrahydrodipicolinate reductase
COORDINATES: similar to AA sequence:RefSeq:WP_011512413.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442436.1
GO:0042586 - peptide deformylase activity [Evidence IEA]
GO:0036211 - protein modification process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011279344.1
GlsB/YeaQ/YmgE family stress response membrane protein
COORDINATES: similar to AA sequence:RefSeq:WP_010197662.1
GO:0016881 - acid-amino acid ligase activity [Evidence IEA]
GO:0009252 - peptidoglycan biosynthetic process [Evidence IEA]
UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase
COORDINATES: similar to AA sequence:RefSeq:WP_011279346.1
copper resistance protein NlpE N-terminal domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_011279347.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442441.1
GO:0004357 - glutamate-cysteine ligase activity [Evidence IEA]
GO:0006750 - glutathione biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011279349.1
GO:0051536 - iron-sulfur cluster binding [Evidence IEA]
GO:0016226 - iron-sulfur cluster assembly [Evidence IEA]
iron-sulfur cluster insertion protein ErpA
COORDINATES: similar to AA sequence:RefSeq:WP_020442443.1
ATP-binding cassette domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_011512421.1
septal ring lytic transglycosylase RlpA family protein
DnaJ is a chaperone associated with the Hsp70 heat-shock system involved in protein folding and renaturation after stress.
COORDINATES: similar to AA sequence:RefSeq:WP_020442444.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512423.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279354.1
GO:0015293 - symporter activity [Evidence IEA]
GO:0032329 - serine transport [Evidence IEA]; GO:0015826 - threonine transport [Evidence IEA]
The DNA polymerase III holoenzyme is the polymerase responsible for the replication of the chromosome.
COORDINATES: similar to AA sequence:RefSeq:WP_011512425.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442447.1
GO:0070006 - metalloaminopeptidase activity [Evidence IEA]
GO:0019538 - protein metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020442448.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512428.1
LPS export ABC transporter permease LptF
COORDINATES: similar to AA sequence:RefSeq:WP_019672056.1
GO:0005886 - plasma membrane [Evidence IEA]
GO:0015221 - lipopolysaccharide transmembrane transporter activity [Evidence IEA]
GO:0015920 - lipopolysaccharide transport [Evidence IEA]
LPS export ABC transporter permease LptG
COORDINATES: similar to AA sequence:RefSeq:WP_010197711.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513662.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279362.1
The majority of these proteins appear to be transcription activators and most are known to negatively regulate their own expression. All possess a potential HTH DNA-binding motif towards their N-termini.
COORDINATES: similar to AA sequence:RefSeq:WP_020443525.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512337.1
Members of this family cleave DNA substrates by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue at the carboxy end of the alignment.
COORDINATES: similar to AA sequence:RefSeq:WP_011512432.1
GO:0009009 - site-specific recombinase activity [Evidence IEA]
GO:0006310 - DNA recombination [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020442452.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512434.1
GO:0097163 - sulfur carrier activity [Evidence IEA]
GO:0002143 - tRNA wobble position uridine thiolation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020442454.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512436.1
GO:0003674 - molecular_function [Evidence IEA]
GO:0008150 - biological_process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011279370.1
All proteins in this family (TIGR00634) for which functions are known are ATP binding proteins involved in the initiation of recombination and recombinational repair.
COORDINATES: similar to AA sequence:RefSeq:WP_011279371.1
GO:0006310 - DNA recombination [Evidence IEA]; GO:0006281 - DNA repair [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010197725.1
pyrimidine/purine nucleoside phosphorylase
COORDINATES: similar to AA sequence:RefSeq:WP_010197727.1
GO:0008173 - RNA methyltransferase activity [Evidence IEA]
GO:0009451 - RNA modification [Evidence IEA]
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB
COORDINATES: similar to AA sequence:RefSeq:WP_011512441.1
GO:0004140 - dephospho-CoA kinase activity [Evidence IEA]
GO:0015937 - coenzyme A biosynthetic process [Evidence IEA]
Dephospho-CoA kinase (CoaE) performs the final step in coenzyme A biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_020442460.1
COORDINATES: similar to AA sequence:RefSeq:WP_003112840.1
type II secretion system F family protein
COORDINATES: similar to AA sequence:RefSeq:WP_011512444.1
GO:0016887 - ATP hydrolysis activity [Evidence IEA]
GO:0009297 - pilus assembly [Evidence IEA]
catalyzes the reversible interconversion of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate
COORDINATES: similar to AA sequence:RefSeq:WP_011512445.1
GO:0004807 - triose-phosphate isomerase activity [Evidence IEA]
GO:0006096 - glycolytic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011279379.1
GO:0015450 - protein-transporting ATPase activity [Evidence IEA]
GO:0043952 - protein transport by the Sec complex [Evidence IEA]
Derived by automated computational analysis using gene prediction method: tRNAscan-SE.
COORDINATES: similar to AA sequence:RefSeq:WP_011279380.1
transcriptional anti-termination Structural and functional similarities between RbfA, NusA, and other bacterial type II KH domains suggest previously unsuspected evolutionary relationships between cold- shock associated proteins
COORDINATES: similar to AA sequence:RefSeq:WP_010197744.1
GO:0006353 - DNA-templated transcription termination [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011959452.1
GO:0003743 - translation initiation factor activity [Evidence IEA]
GO:0006413 - translational initiation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011279383.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512451.1
GO:0004730 - pseudouridylate synthase activity [Evidence IEA]
GO:0006400 - tRNA modification [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020442468.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512454.1
GO:0022627 - cytosolic small ribosomal subunit [Evidence IEA]; GO:0000314 - organellar small ribosomal subunit [Evidence IEA]
GO:0003735 - structural constituent of ribosome [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011279387.1
GO:0004654 - polyribonucleotide nucleotidyltransferase activity [Evidence IEA]
GO:0006402 - mRNA catabolic process [Evidence IEA]
polyribonucleotide nucleotidyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_020442471.1
COORDINATES: similar to AA sequence:RefSeq:WP_019673589.1
YheV family putative metal-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_020442473.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279392.1
COORDINATES: similar to AA sequence:RefSeq:WP_011961450.1
endonuclease/exonuclease/phosphatase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_020442475.1
COORDINATES: similar to AA sequence:RefSeq:WP_007394628.1
alpha-ketoglutarate-dependent dioxygenase AlkB
COORDINATES: similar to AA sequence:RefSeq:WP_011512465.1
COORDINATES: similar to AA sequence:RefSeq:WP_010200751.1
Reversible aldol cleavage or condensation of fructose-1,6-bisphosphate into dihydroxyacetone-phosphate and glyceraldehyde 3-phosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_020442480.1
GO:0004332 - fructose-bisphosphate aldolase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011279399.1
GO:0009228 - thiamine biosynthetic process [Evidence IEA]
COORDINATES: nucleotide motif:Rfam:14.4:RF00059
TPP riboswitch; Derived by automated computational analysis using gene prediction method: cmsearch.
COORDINATES: similar to AA sequence:RefSeq:WP_010200774.1
GO:0005506 - iron ion binding [Evidence IEA]
Arginine biosynthesis and metabolism, Aspartate metabolism.
COORDINATES: similar to AA sequence:RefSeq:WP_011279401.1
GO:0004056 - argininosuccinate lyase activity [Evidence IEA]
GO:0042450 - arginine biosynthetic process via ornithine [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020442485.1
GO:0004418 - hydroxymethylbilane synthase activity [Evidence IEA]
GO:0006779 - porphyrin-containing compound biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011512474.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512475.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442488.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512477.1
GO:0008686 - 3,4-dihydroxy-2-butanone-4-phosphate synthase activity [Evidence IEA]; GO:0003935 - GTP cyclohydrolase II activity [Evidence IEA]
bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II
COORDINATES: similar to AA sequence:RefSeq:WP_011279407.1
replication-associated recombination protein A
COORDINATES: similar to AA sequence:RefSeq:WP_011512479.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442492.1
COORDINATES: similar to AA sequence:RefSeq:WP_010200792.1
GO:0004108 - citrate (Si)-synthase activity [Evidence IEA]
GO:0006099 - tricarboxylic acid cycle [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_017401997.1
GO:0045282 - plasma membrane succinate dehydrogenase complex [Evidence IEA]
GO:0000104 - succinate dehydrogenase activity [Evidence IEA]
succinate dehydrogenase, cytochrome b556 subunit
COORDINATES: similar to AA sequence:RefSeq:WP_011512483.1
succinate dehydrogenase, hydrophobic membrane anchor protein
COORDINATES: similar to AA sequence:RefSeq:WP_019672358.1
GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; GO:0016627 - oxidoreductase activity, acting on the CH-CH group of donors [Evidence IEA]
GO:0022900 - electron transport chain [Evidence IEA]; GO:0006099 - tricarboxylic acid cycle [Evidence IEA]
succinate dehydrogenase flavoprotein subunit
COORDINATES: similar to AA sequence:RefSeq:WP_016651020.1
succinate dehydrogenase iron-sulfur subunit
COORDINATES: similar to AA sequence:RefSeq:WP_011279415.1
GO:0004591 - oxoglutarate dehydrogenase (succinyl-transferring) activity [Evidence IEA]; GO:0030976 - thiamine pyrophosphate binding [Evidence IEA]
2-oxoglutarate dehydrogenase E1 component
COORDINATES: similar to AA sequence:RefSeq:WP_003667308.1
GO:0045252 - oxoglutarate dehydrogenase complex [Evidence IEA]
GO:0004149 - dihydrolipoyllysine-residue succinyltransferase activity [Evidence IEA]
2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_003661018.1
GO:0004148 - dihydrolipoyl dehydrogenase activity [Evidence IEA]
GO:0045454 - cell redox homeostasis [Evidence IEA]; GO:0051068 - dihydrolipoamide metabolic process [Evidence IEA]; GO:0006096 - glycolytic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:YP_004996414.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0003824 - catalytic activity [Evidence IEA]; GO:0046872 - metal ion binding [Evidence IEA]
ADP-forming succinate--CoA ligase subunit beta
COORDINATES: similar to AA sequence:RefSeq:WP_019672364.1
GO:0003824 - catalytic activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011512491.1
GO:0003978 - UDP-glucose 4-epimerase activity [Evidence IEA]
GO:0006012 - galactose metabolic process [Evidence IEA]
transfer nucleotides onto phosphosugars.
COORDINATES: similar to AA sequence:RefSeq:WP_020442499.1
UTP--glucose-1-phosphate uridylyltransferase
catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate
COORDINATES: similar to AA sequence:RefSeq:WP_020442500.1
GO:0004347 - glucose-6-phosphate isomerase activity [Evidence IEA]
GO:0006094 - gluconeogenesis [Evidence IEA]; GO:0006096 - glycolytic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020442501.1
UDP-glucose/GDP-mannose dehydrogenase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_010200849.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442503.1
nucleoside triphosphate pyrophosphohydrolase
COORDINATES: similar to AA sequence:RefSeq:WP_020442504.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442505.1
GO:0004652 - polynucleotide adenylyltransferase activity [Evidence IEA]; GO:0003723 - RNA binding [Evidence IEA]
GO:0006378 - mRNA polyadenylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_019673115.1
GO:0003848 - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity [Evidence IEA]
GO:0009396 - folic acid-containing compound biosynthetic process [Evidence IEA]
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase
COORDINATES: similar to AA sequence:RefSeq:WP_010200855.1
GO:0003864 - 3-methyl-2-oxobutanoate hydroxymethyltransferase activity [Evidence IEA]
GO:0015940 - pantothenate biosynthetic process [Evidence IEA]
3-methyl-2-oxobutanoate hydroxymethyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_011279430.1
GO:0004592 - pantoate-beta-alanine ligase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011279431.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279432.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279433.1
thiol:disulfide interchange protein DsbA/DsbL
COORDINATES: similar to AA sequence:RefSeq:WP_020442510.1
GO:0008689 - 3-demethylubiquinone-9 3-O-methyltransferase activity [Evidence IEA]
GO:0006744 - ubiquinone biosynthetic process [Evidence IEA]
bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG
COORDINATES: similar to AA sequence:RefSeq:WP_011512506.1
GO:0016787 - hydrolase activity [Evidence IEA]
GO:0008152 - metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020442511.1
GO:0016491 - oxidoreductase activity [Evidence IEA]
DksA is involved in translational regulation of RpoS
COORDINATES: similar to AA sequence:RefSeq:WP_000146343.1
GO:0008270 - zinc ion binding [Evidence IEA]
DksA/TraR family C4-type zinc finger protein
COORDINATES: similar to AA sequence:RefSeq:WP_010200868.1
COORDINATES: similar to AA sequence:RefSeq:WP_003096259.1
GO:0000160 - phosphorelay signal transduction system [Evidence IEA]; GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]
two-component system response regulator OmpR
COORDINATES: similar to AA sequence:RefSeq:WP_020442513.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442515.1
saccharopine dehydrogenase NADP-binding domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:YP_004997167.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279444.1
GO:0008124 - 4-alpha-hydroxytetrahydrobiopterin dehydratase activity [Evidence IEA]
GO:0006729 - tetrahydrobiopterin biosynthetic process [Evidence IEA]
4a-hydroxytetrahydrobiopterin dehydratase
COORDINATES: similar to AA sequence:RefSeq:WP_011512515.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512518.1
GO:0045900 - negative regulation of translational elongation [Evidence IEA]
energy-dependent translational throttle protein EttA
COORDINATES: similar to AA sequence:RefSeq:WP_011279447.1
GO:0004366 - glycerol-3-phosphate O-acyltransferase activity [Evidence IEA]
GO:0008654 - phospholipid biosynthetic process [Evidence IEA]
glycerol-3-phosphate 1-O-acyltransferase PlsB
COORDINATES: similar to AA sequence:RefSeq:WP_020442522.1
GO:0002161 - aminoacyl-tRNA editing activity [Evidence IEA]
GO:0043039 - tRNA aminoacylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011512521.1
5-carboxymethyl-2-hydroxymuconate Delta-isomerase
COORDINATES: similar to AA sequence:RefSeq:WP_003656236.1
acyl-CoA dehydrogenase C-terminal domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_011512523.1
Aromatic amino acid biosynthesis, Chorismate biosynthesis
COORDINATES: similar to AA sequence:RefSeq:WP_011279452.1
GO:0004764 - shikimate 3-dehydrogenase (NADP+) activity [Evidence IEA]
GO:0019632 - shikimate metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011512525.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442528.1
COORDINATES: similar to AA sequence:RefSeq:WP_010200909.1
Recognizes and cleaves methylated sequences.
COORDINATES: similar to AA sequence:RefSeq:WP_011279456.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442530.1
GO:0008932 - lytic endotransglycosylase activity [Evidence IEA]
GO:0071555 - cell wall organization [Evidence IEA]; GO:0009252 - peptidoglycan biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020442531.1
GO:0004798 - thymidylate kinase activity [Evidence IEA]
GO:0015949 - nucleobase-containing small molecule interconversion [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011512530.1
GO:0015299 - solute:proton antiporter activity [Evidence IEA]
GO:0006812 - cation transport [Evidence IEA]; GO:0055085 - transmembrane transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011279460.1
GO:0030288 - outer membrane-bounded periplasmic space [Evidence IEA]
GO:0005515 - protein binding [Evidence IEA]; GO:0004252 - serine-type endopeptidase activity [Evidence IEA]
GO:0006508 - proteolysis [Evidence IEA]; GO:0006950 - response to stress [Evidence IEA]
Diaminopimellate biosynthesis, Lysine biosynthesis via the diaminopimellate pathway
COORDINATES: similar to AA sequence:RefSeq:WP_010196115.1
GO:0008840 - 4-hydroxy-tetrahydrodipicolinate synthase activity [Evidence IEA]
4-hydroxy-tetrahydrodipicolinate synthase
COORDINATES: similar to AA sequence:RefSeq:WP_020442535.1
COORDINATES: similar to AA sequence:RefSeq:WP_010196111.1
GO:0004639 - phosphoribosylaminoimidazolesuccinocarboxamide synthase activity [Evidence IEA]
GO:0006164 - purine nucleotide biosynthetic process [Evidence IEA]
phosphoribosylaminoimidazolesuccinocarboxamide synthase
COORDINATES: similar to AA sequence:RefSeq:WP_020442536.1
COORDINATES: similar to AA sequence:RefSeq:WP_010196108.1
GO:0003905 - alkylbase DNA N-glycosylase activity [Evidence IEA]; GO:0003677 - DNA binding [Evidence IEA]
GO:0006284 - base-excision repair [Evidence IEA]
frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_011512537.1
COORDINATES: protein motif:HMM:NF024751.2
COORDINATES: similar to AA sequence:RefSeq:WP_011512540.1
COORDINATES: protein motif:HMM:NF013717.2
incomplete; partial in the middle of a contig; missing N-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_020442540.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512543.1
COORDINATES: similar to AA sequence:RefSeq:WP_000212737.1
zinc ribbon domain-containing protein YjdM
COORDINATES: similar to AA sequence:RefSeq:WP_020442542.1
GO:0042286 - glutamate-1-semialdehyde 2,1-aminomutase activity [Evidence IEA]
glutamate-1-semialdehyde 2,1-aminomutase
COORDINATES: similar to AA sequence:RefSeq:WP_011512547.1
GO:0004309 - exopolyphosphatase activity [Evidence IEA]; GO:0000287 - magnesium ion binding [Evidence IEA]
GO:0006798 - polyphosphate catabolic process [Evidence IEA]
It catalyzes the first step in the synthesis of long-chain fatty acids which involves the carboxylation of acetyl-CoA to malonyl-CoA
COORDINATES: similar to AA sequence:RefSeq:WP_011512548.1
GO:0009317 - acetyl-CoA carboxylase complex [Evidence IEA]
GO:0003989 - acetyl-CoA carboxylase activity [Evidence IEA]
GO:0006633 - fatty acid biosynthetic process [Evidence IEA]
acetyl-CoA carboxylase carboxyltransferase subunit alpha
COORDINATES: similar to AA sequence:RefSeq:WP_020442545.1
GO:0016879 - ligase activity, forming carbon-nitrogen bonds [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020442547.1
GO:0004735 - pyrroline-5-carboxylate reductase activity [Evidence IEA]
GO:0006561 - proline biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011279478.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279479.1
hydroxymethylpyrimidine/phosphomethylpyrimidine kinase
COORDINATES: similar to AA sequence:RefSeq:WP_020442550.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279481.1
GO:0004068 - aspartate 1-decarboxylase activity [Evidence IEA]
Peptidyl-tRNA hydrolase (PTH) is a bacterial enzyme that cleaves peptidyl-tRNA or N-acyl-aminoacyl-tRNA to yield free peptides or N-acyl-amino acids and tRNA.
COORDINATES: similar to AA sequence:RefSeq:WP_011279482.1
GO:0004045 - aminoacyl-tRNA hydrolase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020442553.1
GO:0008097 - 5S rRNA binding [Evidence IEA]; GO:0003735 - structural constituent of ribosome [Evidence IEA]
50S ribosomal protein L25/general stress protein Ctc
Pentose Phosphate Pathway -> Histidine biosynthesis, pyrimidine biosynthesis, and purine biosynthesis
COORDINATES: similar to AA sequence:RefSeq:WP_011279484.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279485.1
GO:0050515 - 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity [Evidence IEA]
GO:0016114 - terpenoid biosynthetic process [Evidence IEA]
4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase
COORDINATES: similar to AA sequence:RefSeq:WP_020442555.1
GO:0008320 - protein transmembrane transporter activity [Evidence IEA]
GO:0009306 - protein secretion [Evidence IEA]
lipoprotein insertase outer membrane protein LolB
COORDINATES: similar to AA sequence:RefSeq:WP_020442556.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442557.1
GO:0008883 - glutamyl-tRNA reductase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010196048.1
aminotransferase class V-fold PLP-dependent enzyme
COORDINATES: similar to AA sequence:RefSeq:WP_011512564.1
COORDINATES: similar to AA sequence:RefSeq:WP_010196042.1
YeeE/YedE thiosulfate transporter family protein
COORDINATES: similar to AA sequence:RefSeq:WP_011279492.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442561.1
NADPH-dependent 2,4-dienoyl-CoA reductase
COORDINATES: similar to AA sequence:RefSeq:WP_020442567.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512575.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279496.1
GO:0003987 - acetate-CoA ligase activity [Evidence IEA]
GO:0019427 - acetyl-CoA biosynthetic process from acetate [Evidence IEA]
GO:0015074 - DNA integration [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010195999.1
GO:0008444 - CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity [Evidence IEA]
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_011279498.1
pyridoxamine 5'-phosphate oxidase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_003673496.1
GO:0004642 - phosphoribosylformylglycinamidine synthase activity [Evidence IEA]
phosphoribosylformylglycinamidine synthase
COORDINATES: similar to AA sequence:RefSeq:WP_005019524.1
COORDINATES: protein motif:HMM:NF025637.2
COORDINATES: similar to AA sequence:RefSeq:WP_076612078.1
frameshifted; incomplete; partial in the middle of a contig; missing N-terminus and C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: nucleotide motif:Rfam:14.4:RF01497
AL1L pseudoknot; Derived by automated computational analysis using gene prediction method: cmsearch.
COORDINATES: similar to AA sequence:RefSeq:WP_010199363.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279827.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0004803 - transposase activity [Evidence IEA]
GO:0006313 - transposition, DNA-mediated [Evidence IEA]
frameshifted; incomplete; partial in the middle of a contig; missing N-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_010200569.1
COORDINATES: similar to AA sequence:RefSeq:WP_011959606.1
incomplete; partial in the middle of a contig; missing C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_010195955.1
GO:0043022 - ribosome binding [Evidence IEA]
GO:0017148 - negative regulation of translation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020442578.1
nicotinate-nicotinamide nucleotide adenylyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_020442579.1
GO:0016407 - acetyltransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011512590.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512591.1
Lysine biosynthesis via the diaminopimellate pathway.
COORDINATES: similar to AA sequence:RefSeq:WP_020442582.1
GO:0008836 - diaminopimelate decarboxylase activity [Evidence IEA]
Lysine biosynthesis via diaminopimellate synthase
COORDINATES: similar to AA sequence:RefSeq:WP_011279512.1
GO:0008837 - diaminopimelate epimerase activity [Evidence IEA]
Possible site-specific recombinase that acts on cer sequence of ColE1, effects chromosome segregation at cell division.
COORDINATES: similar to AA sequence:RefSeq:WP_020442584.1
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
COORDINATES: similar to AA sequence:RefSeq:WP_011512595.1
required for the transcription of promoters that have a characteristic -24 and -12 consensus recognition element but which are devoid of the typical -10,-35 sequences recognized by the major sigma factors.
COORDINATES: similar to AA sequence:RefSeq:WP_020442586.1
GO:0016987 - sigma factor activity [Evidence IEA]
GO:0006352 - DNA-templated transcription initiation [Evidence IEA]
possible binding to sigma factor 54. implicated in biofilm formation in Bacillus and quorom sensing in P. stutzeri
COORDINATES: similar to AA sequence:RefSeq:WP_011512597.1
GO:0022626 - cytosolic ribosome [Evidence IEA]; GO:0005840 - ribosome [Evidence IEA]
GO:0045182 - translation regulator activity [Evidence IEA]
GO:0009386 - translational attenuation [Evidence IEA]
ribosome-associated translation inhibitor RaiA
COORDINATES: similar to AA sequence:RefSeq:WP_011279517.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512599.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279519.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442590.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512602.1
GO:0004222 - metalloendopeptidase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011512603.1
COORDINATES: similar to AA sequence:RefSeq:WP_011235429.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442592.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442593.1
GO:0009055 - electron transfer activity [Evidence IEA]; GO:0020037 - heme binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011512606.1
tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD
COORDINATES: similar to AA sequence:RefSeq:WP_020442595.1
The majority of these proteins appear to be transcription activators and most are known to negatively regulate their own expression.
COORDINATES: similar to AA sequence:RefSeq:WP_011279527.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512609.1
can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; incomplete; partial in the middle of a contig; missing N-terminus and C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
spermidine/putrescine ABC transporter permease PotC
COORDINATES: similar to AA sequence:RefSeq:WP_020442600.1
Pyruvate metabolism, Lactate biosynthesis
COORDINATES: similar to AA sequence:RefSeq:WP_020442601.1
GO:0004462 - lactoylglutathione lyase activity [Evidence IEA]
GO:0005975 - carbohydrate metabolic process [Evidence IEA]; GO:0051596 - methylglyoxal catabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011512615.1
GO:0004109 - coproporphyrinogen oxidase activity [Evidence IEA]
oxygen-dependent coproporphyrinogen oxidase
COORDINATES: similar to AA sequence:RefSeq:WP_011512616.1
GO:0003935 - GTP cyclohydrolase II activity [Evidence IEA]
Catalyzes the thiamine pyrophosphoate-dependent acyloin condensation reaction between carbon atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate; synthesis isopentenyl diphosphate
COORDINATES: similar to AA sequence:RefSeq:WP_011279532.1
GO:0008661 - 1-deoxy-D-xylulose-5-phosphate synthase activity [Evidence IEA]
GO:0009240 - isopentenyl diphosphate biosynthetic process [Evidence IEA]; GO:0008615 - pyridoxine biosynthetic process [Evidence IEA]; GO:0009228 - thiamine biosynthetic process [Evidence IEA]
inositol/phosphatidylinositol phosphatase activity
COORDINATES: similar to AA sequence:RefSeq:WP_011279533.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512619.1
wax ester/triacylglycerol synthase family O-acyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_011512620.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442610.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442611.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0016887 - ATP hydrolysis activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020442612.1
COORDINATES: similar to AA sequence:RefSeq:WP_010195835.1
COORDINATES: protein motif:HMM:NF012694.2
COORDINATES: similar to AA sequence:RefSeq:WP_020442618.1
protein-disulfide reductase DsbD N-terminal domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_011512631.1
protein-disulfide reductase DsbD family protein
COORDINATES: similar to AA sequence:RefSeq:WP_011512632.1
natural transformation with exogenous DNA
COORDINATES: similar to AA sequence:RefSeq:WP_020442621.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442622.1
GO:0015627 - type II protein secretion system complex [Evidence IEA]
GO:0015628 - protein secretion by the type II secretion system [Evidence IEA]
COORDINATES: protein motif:HMM:TIGR02523.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512636.1
GO:0043683 - type IV pilus assembly [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011512637.1
COORDINATES: protein motif:HMM:NF017388.2
COORDINATES: similar to AA sequence:RefSeq:WP_003112842.1
prepilin-type N-terminal cleavage/methylation domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_009767605.1
COORDINATES: similar to AA sequence:RefSeq:WP_016352167.1
COORDINATES: protein motif:HMM:NF016800.2
COORDINATES: similar to AA sequence:RefSeq:WP_011514282.1
COORDINATES: protein motif:HMM:NF023379.2
COORDINATES: similar to AA sequence:RefSeq:WP_005804366.1
COORDINATES: similar to AA sequence:RefSeq:WP_016138692.1
This family of proteins is named after the Salmonella typhimurium MutS protein that is involved in replication repair and plays a role in preventing recombination between non-identical sequences.
COORDINATES: similar to AA sequence:RefSeq:WP_011279555.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0030983 - mismatched DNA binding [Evidence IEA]
GO:0006298 - mismatch repair [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020442631.1
GO:0006886 - intracellular protein transport [Evidence IEA]; GO:0017038 - protein import [Evidence IEA]; GO:0006605 - protein targeting [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020442632.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442633.1
COORDINATES: similar to AA sequence:RefSeq:WP_010195780.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279560.1
Threonine biosynthesis, Lysine biosynthesis
COORDINATES: similar to AA sequence:RefSeq:WP_020442636.1
Required for disulfide bond formation in some periplasmic proteins.
COORDINATES: similar to AA sequence:RefSeq:WP_011512652.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512653.1
COORDINATES: similar to AA sequence:RefSeq:WP_010195773.1
GO:0004540 - ribonuclease activity [Evidence IEA]
GO:0006401 - RNA catabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020442640.1
GO:0001522 - pseudouridine synthesis [Evidence IEA]; GO:0009451 - RNA modification [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020442641.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512657.1
GO:0005525 - GTP binding [Evidence IEA]; GO:0003924 - GTPase activity [Evidence IEA]; GO:0043022 - ribosome binding [Evidence IEA]
GO:0042254 - ribosome biogenesis [Evidence IEA]
ribosome biogenesis GTP-binding protein YihA/YsxC
COORDINATES: similar to AA sequence:RefSeq:WP_020442643.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279569.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442644.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512661.1
possibly involved in maintaining the structural integrity of the cell envelope
COORDINATES: similar to AA sequence:RefSeq:WP_011279572.1
GO:0019867 - outer membrane [Evidence IEA]
outer membrane protein assembly factor BamE
The Ferric uptake regulator or FUR family includes metal ion uptake regulator proteins, which bind to the operator DNA and control the transcription of metal ion-responsive genes.
COORDINATES: similar to AA sequence:RefSeq:WP_011512663.1
GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]
GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]
ferric iron uptake transcriptional regulator
COORDINATES: similar to AA sequence:RefSeq:WP_011512664.1
GO:0043107 - type IV pilus-dependent motility [Evidence IEA]
Pilus retraction protein: required for twitching motility and social gliding. Protein involved in type II secretion.
COORDINATES: similar to AA sequence:RefSeq:WP_011512665.1
type IV pilus twitching motility protein PilT
COORDINATES: similar to AA sequence:RefSeq:WP_020442649.1
GO:0030170 - pyridoxal phosphate binding [Evidence IEA]
YggS family pyridoxal phosphate-dependent enzyme
COORDINATES: similar to AA sequence:RefSeq:WP_020442650.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512668.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0003952 - NAD+ synthase (glutamine-hydrolyzing) activity [Evidence IEA]
GO:0009435 - NAD biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011512669.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512670.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442654.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0004824 - lysine-tRNA ligase activity [Evidence IEA]; GO:0000166 - nucleotide binding [Evidence IEA]
GO:0006430 - lysyl-tRNA aminoacylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011279582.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442656.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0046872 - metal ion binding [Evidence IEA]; GO:0004638 - phosphoribosylaminoimidazole carboxylase activity [Evidence IEA]
GO:0006189 - 'de novo' IMP biosynthetic process [Evidence IEA]
5-(carboxyamino)imidazole ribonucleotide synthase
COORDINATES: similar to AA sequence:RefSeq:WP_011512674.1
GO:0009320 - phosphoribosylaminoimidazole carboxylase complex [Evidence IEA]
GO:0004638 - phosphoribosylaminoimidazole carboxylase activity [Evidence IEA]
GO:0009152 - purine ribonucleotide biosynthetic process [Evidence IEA]
5-(carboxyamino)imidazole ribonucleotide mutase
COORDINATES: similar to AA sequence:RefSeq:WP_010201916.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442660.1
rhomboid family intramembrane serine protease
COORDINATES: similar to AA sequence:RefSeq:WP_020442662.1
Possible porin-like integral membrane proteins
COORDINATES: similar to AA sequence:RefSeq:WP_011512678.1
hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety.
COORDINATES: similar to AA sequence:RefSeq:WP_020442664.1
GO:0004553 - hydrolase activity, hydrolyzing O-glycosyl compounds [Evidence IEA]
GO:0005975 - carbohydrate metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020442665.1
COORDINATES: similar to AA sequence:RefSeq:WP_005402252.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512681.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442667.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442669.1
rRNA large subunit pseudouridine synthase E
COORDINATES: similar to AA sequence:RefSeq:WP_004674738.1
Converts isocitrate to alpha ketoglutarate; frameshifted; incomplete; partial in the middle of a contig; missing C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_020442671.1
GO:0004450 - isocitrate dehydrogenase (NADP+) activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011512686.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442673.1
GO:0008813 - chorismate lyase activity [Evidence IEA]
Glysine metabolism and biosynthesis, Serine metabolism and biosynthesis, Lysine degradation
COORDINATES: similar to AA sequence:RefSeq:WP_011961296.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512690.1
RNA binding (GO:0003723) endoribonuclease activity (GO:0004521)
COORDINATES: similar to AA sequence:RefSeq:WP_020442676.1
GO:0003676 - nucleic acid binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011512692.1
GO:0004350 - glutamate-5-semialdehyde dehydrogenase activity [Evidence IEA]; GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011512694.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279603.1
transporter substrate-binding domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_011512696.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442682.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442683.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512700.1
fumarylacetoacetate hydrolase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_011279608.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512702.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512703.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512704.1
GO:0009982 - pseudouridine synthase activity [Evidence IEA]; GO:0003723 - RNA binding [Evidence IEA]
glutamate/aspartate ABC transporter substrate-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_010201841.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512706.1
GO:0055052 - ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [Evidence IEA]; GO:0005886 - plasma membrane [Evidence IEA]
GO:0015837 - amine transport [Evidence IEA]
The N-terminal region of this protein, as described by TIGR01726, is a three transmembrane segment that identifies a subfamily of ABC transporter permease subunits, which specificities that include histidine, arginine, glutamine, glutamate, L-cystine (sic), the opines (in Agrobacterium) octopine and nopaline, etc.; The N-terminal region of this protein, as described by TIGR01726, is a three transmembrane segment that identifies a subfamily of ABC transporter permease subunits, which specificities that include histidine, arginine, glutamine, glutamate, L-cystine (sic), the opines (in Agrobacterium) octopine and nopaline, etc; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_003082761.1
amino acid ABC transporter ATP-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_011512708.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279616.1
Leucine, Isoleucine, and Valine degradation, Propionate metabolism
COORDINATES: similar to AA sequence:RefSeq:WP_011279617.1
Leucine, Isoleucine, and Valine Degradation, Lysine Degradation, Beta-alanine metabolism, Tryptophan metabolism
COORDINATES: similar to AA sequence:RefSeq:WP_011512711.1
enoyl-CoA hydratase/isomerase family protein
Leucine, Isoleucine, and Valine Degradation
COORDINATES: similar to AA sequence:RefSeq:WP_020442695.1
acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha
Leucine degradation, Butanoate metabolism
COORDINATES: similar to AA sequence:RefSeq:WP_011279620.1
COORDINATES: similar to AA sequence:RefSeq:WP_017396625.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442698.1
Attaches biotin to lysine within active site of biotin enzymes
COORDINATES: similar to AA sequence:RefSeq:WP_011512716.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444447.1
sulfite exporter TauE/SafE family protein
The SMC proteins are essential for successful chromosome transmission during replication and segregation of the genome.
COORDINATES: similar to AA sequence:RefSeq:WP_020442702.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442703.1
DNA ligase catalyses the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilising NAD(+) as a cofactor.
COORDINATES: similar to AA sequence:RefSeq:WP_011512721.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0003911 - DNA ligase (NAD+) activity [Evidence IEA]
GO:0006281 - DNA repair [Evidence IEA]; GO:0006260 - DNA replication [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513233.1
COORDINATES: protein motif:HMM:NF025840.2
DarT ssDNA thymidine ADP-ribosyltransferase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_011512723.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279631.1
GO:1904047 - S-adenosyl-L-methionine binding [Evidence IEA]
recognizes stalled ribosomes such as occur during translation from message that lacks a stop codon.
COORDINATES: similar to AA sequence:RefSeq:WP_011279632.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512729.1
GO:0004595 - pantetheine-phosphate adenylyltransferase activity [Evidence IEA]
pantetheine-phosphate adenylyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_011512730.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442710.1
GO:0004015 - adenosylmethionine-8-amino-7-oxononanoate transaminase activity [Evidence IEA]
GO:0009102 - biotin biosynthetic process [Evidence IEA]
adenosylmethionine--8-amino-7-oxononanoate transaminase
COORDINATES: similar to AA sequence:RefSeq:WP_020442711.1
GO:0004141 - dethiobiotin synthase activity [Evidence IEA]
COORDINATES: nucleotide motif:Rfam:14.4:RF00010
Derived by automated computational analysis using gene prediction method: cmsearch.
COORDINATES: similar to AA sequence:RefSeq:WP_010201785.1
GO:0005525 - GTP binding [Evidence IEA]; GO:0003924 - GTPase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011279638.1
GO:0004252 - serine-type endopeptidase activity [Evidence IEA]
GO:0009306 - protein secretion [Evidence IEA]; GO:0006465 - signal peptide processing [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011512735.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279640.1
GO:0004525 - ribonuclease III activity [Evidence IEA]
GO:0006396 - RNA processing [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020442715.1
GO:0005525 - GTP binding [Evidence IEA]; GO:0003723 - RNA binding [Evidence IEA]
Involved in RecF pathway of recombination.
COORDINATES: similar to AA sequence:RefSeq:WP_011279642.1
DNA repair protein RecO C-terminal domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_011279643.1
GO:0033856 - pyridoxine 5'-phosphate synthase activity [Evidence IEA]
GO:0008615 - pyridoxine biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011512740.1
COORDINATES: similar to AA sequence:RefSeq:WP_003662682.1
COORDINATES: similar to AA sequence:RefSeq:WP_010201777.1
GO:0006950 - response to stress [Evidence IEA]; GO:0006412 - translation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011512743.1
GO:0008381 - mechanosensitive ion channel activity [Evidence IEA]
GO:0034220 - ion transmembrane transport [Evidence IEA]
large conductance mechanosensitive channel protein MscL
COORDINATES: similar to AA sequence:RefSeq:WP_020442721.1
Formamidopyrimidine-DNA glycosylase (Fpg) is a DNA repair enzyme that excises oxidized purines from damaged DNA (base excision repair).
COORDINATES: similar to AA sequence:RefSeq:WP_011279649.1
GO:0003684 - damaged DNA binding [Evidence IEA]; GO:0019104 - DNA N-glycosylase activity [Evidence IEA]; GO:0003906 - DNA-(apurinic or apyrimidinic site) endonuclease activity [Evidence IEA]; GO:0016799 - hydrolase activity, hydrolyzing N-glycosyl compounds [Evidence IEA]; GO:0003676 - nucleic acid binding [Evidence IEA]; GO:0008534 - oxidized purine nucleobase lesion DNA N-glycosylase activity [Evidence IEA]; GO:0008270 - zinc ion binding [Evidence IEA]
GO:0006284 - base-excision repair [Evidence IEA]; GO:0006281 - DNA repair [Evidence IEA]
bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase
RelA produces pppGpp (or ppGpp) from ATP and GTP (or GDP). SpoT degrades ppGpp, but may also act as a secondary ppGpp synthetase
COORDINATES: similar to AA sequence:RefSeq:WP_011512746.1
bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
COORDINATES: similar to AA sequence:RefSeq:WP_011279651.1
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD
COORDINATES: similar to AA sequence:RefSeq:WP_011512748.1
Cysteine Metabolism, Selenoamino Acid Metabolism, Sulfur Metabolism: Fixation
COORDINATES: similar to AA sequence:RefSeq:WP_011512749.1
GO:0004124 - cysteine synthase activity [Evidence IEA]
GO:0006535 - cysteine biosynthetic process from serine [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011512750.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512751.1
crotonase/enoyl-CoA hydratase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_011512752.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279657.1
COORDINATES: similar to AA sequence:RefSeq:WP_010201759.1
GO:0003746 - translation elongation factor activity [Evidence IEA]
GO:0006414 - translational elongation [Evidence IEA]
Bacterial lytic transglycosylases degrade murein via cleavage of the beta-1,4- glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine, with the concomitant formation of a 1,6-anhydrobond in the muramic acid residue.
COORDINATES: similar to AA sequence:RefSeq:WP_020442732.1
lytic transglycosylase domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_010201757.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512763.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512764.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442736.1
lysophospholipid acyltransferase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_020442737.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442738.1
Autonomous mobile genetic elements such as transposon or insertion sequences (IS) encode an enzyme, transposase, that is required for excising and inserting the mobile element.
COORDINATES: similar to AA sequence:RefSeq:WP_015589626.1
COORDINATES: protein motif:HMM:NF019843.2
COORDINATES: similar to AA sequence:RefSeq:WP_076611467.1
internal stop; incomplete; partial in the middle of a contig; missing N-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
integrase core domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_007394337.1
COORDINATES: similar to AA sequence:RefSeq:WP_007395555.1
GO:0004190 - aspartic-type endopeptidase activity [Evidence IEA]
GO:0009306 - protein secretion [Evidence IEA]; GO:0006508 - proteolysis [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011961109.1
GO:0004822 - isoleucine-tRNA ligase activity [Evidence IEA]
GO:0006428 - isoleucyl-tRNA aminoacylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010201747.1
hydrolase activity:adenine deaminase that hydrolyses adenine to form hypoxanthine and ammonia which is important for adenine utilization as a purine and also as a nitrogen source
COORDINATES: similar to AA sequence:RefSeq:WP_011512775.1
bifunctional GNAT family N-acetyltransferase/carbon-nitrogen hydrolase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_020442745.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279675.1
COORDINATES: similar to AA sequence:RefSeq:WP_003663188.1
GO:0051287 - NAD binding [Evidence IEA]; GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011279677.1
COORDINATES: protein motif:HMM:NF025612.2
COORDINATES: similar to AA sequence:RefSeq:WP_005401325.1
COORDINATES: similar to AA sequence:RefSeq:WP_010201739.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442749.1
GO:0009086 - methionine biosynthetic process [Evidence IEA]
Methionine metabolism, Sulfur Fixation and Metabolism
COORDINATES: similar to AA sequence:RefSeq:WP_011279682.1
GO:0016747 - acyltransferase activity, transferring groups other than amino-acyl groups [Evidence IEA]
GO:0009058 - biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020442751.1
GO:0004325 - ferrochelatase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020442752.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442754.1
GO:0008408 - 3'-5' exonuclease activity [Evidence IEA]; GO:0003677 - DNA binding [Evidence IEA]; GO:0003887 - DNA-directed DNA polymerase activity [Evidence IEA]; GO:0003676 - nucleic acid binding [Evidence IEA]
GO:0006261 - DNA-templated DNA replication [Evidence IEA]
Involved in response to stress: organic hydroperoxide detoxification
COORDINATES: similar to AA sequence:RefSeq:WP_011512788.1
GO:0004601 - peroxidase activity [Evidence IEA]
GO:0006979 - response to oxidative stress [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007395735.1
GO:0003924 - GTPase activity [Evidence IEA]
GO:0006415 - translational termination [Evidence IEA]
COORDINATES: protein motif:HMM:NF023166.2
COORDINATES: similar to AA sequence:RefSeq:WP_020442759.1
COORDINATES: similar to AA sequence:RefSeq:WP_005198081.1
COORDINATES: similar to AA sequence:RefSeq:WP_010197133.1
GO:0008999 - peptide-alanine-alpha-N-acetyltransferase activity [Evidence IEA]
GO:0036211 - protein modification process [Evidence IEA]; GO:0042254 - ribosome biogenesis [Evidence IEA]
ribosomal protein S18-alanine N-acetyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_011512795.1
Controls protein half-life through N-end rule degradation pathway.
COORDINATES: similar to AA sequence:RefSeq:WP_011279693.1
GO:0008914 - leucyltransferase activity [Evidence IEA]
leucyl/phenylalanyl-tRNA--protein transferase
COORDINATES: similar to AA sequence:RefSeq:WP_011512797.1
GO:0004791 - thioredoxin-disulfide reductase activity [Evidence IEA]
COORDINATES: protein motif:HMM:NF024882.2
DNA translocase FtsK 4TM domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_019520807.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442765.1
GO:0008168 - methyltransferase activity [Evidence IEA]
23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH
COORDINATES: similar to AA sequence:RefSeq:WP_010196511.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512806.1
GO:0008773 - [protein-PII] uridylyltransferase activity [Evidence IEA]
DUF294 nucleotidyltransferase-like domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_011512807.1
GO:0009016 - succinyldiaminopimelate transaminase activity [Evidence IEA]
GO:0019877 - diaminopimelate biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020442772.1
Signal transduction: Inactivates protein PII -> upregulation of glutamine synthesis genes
COORDINATES: similar to AA sequence:RefSeq:WP_020442773.1
GO:0018177 - protein uridylylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011512810.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279704.1
COORDINATES: protein motif:HMM:NF021526.2
C-5 cytosine-specific DNA methylases specifically methylate the C-5 carbon of cytosines in DNA to produce C5-methylcytosine. In bacteria, these enzymes are a component of restriction-modification systems.
COORDINATES: similar to AA sequence:RefSeq:WP_005035240.1
COORDINATES: similar to AA sequence:RefSeq:WP_005035239.1
MvaI/BcnI family restriction endonuclease
COORDINATES: similar to AA sequence:RefSeq:WP_011512817.1
GO:0008705 - methionine synthase activity [Evidence IEA]; GO:0008270 - zinc ion binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011512818.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512819.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442782.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442783.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442784.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512823.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442788.1
COORDINATES: similar to AA sequence:RefSeq:WP_017395934.1
type I restriction-modification system subunit M N-terminal domain-containing protein
type I restriction-modification system subunit M
COORDINATES: protein motif:HMM:NF013579.2
GO:0006304 - DNA modification [Evidence IEA]
Glutathione metabolism, Conjugates Glutathione with a variety of hydrocarbons.
COORDINATES: similar to AA sequence:RefSeq:WP_011513587.1
glutathione S-transferase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_005262957.1
COORDINATES: similar to AA sequence:RefSeq:WP_011768680.1
COORDINATES: protein motif:HMM:NF012421.2
COORDINATES: similar to AA sequence:RefSeq:WP_011280644.1
frameshifted; internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_019837815.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0004519 - endonuclease activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011512827.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279725.1
COORDINATES: similar to AA sequence:RefSeq:WP_013108116.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512830.1
GO:0043867 - 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity [Evidence IEA]; GO:0033739 - preQ1 synthase activity [Evidence IEA]
GO:0008616 - queuosine biosynthetic process [Evidence IEA]
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
NADPH-dependent 7-cyano-7-deazaguanine reductase QueF
COORDINATES: similar to AA sequence:RefSeq:WP_011512831.1
GO:0002161 - aminoacyl-tRNA editing activity [Evidence IEA]; GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA]; GO:0000166 - nucleotide binding [Evidence IEA]; GO:0004827 - proline-tRNA ligase activity [Evidence IEA]
GO:0006433 - prolyl-tRNA aminoacylation [Evidence IEA]; GO:0006418 - tRNA aminoacylation for protein translation [Evidence IEA]
DNA photolyases are enzymes that bind to DNA containing pyrimidine dimers (induced by exposure to UV): on absorption of visible light, they catalyse dimer splitting into the constituent monomers, a process called photoreactivation.
COORDINATES: similar to AA sequence:RefSeq:WP_020442794.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512834.1
GO:0004640 - phosphoribosylanthranilate isomerase activity [Evidence IEA]
GO:0000162 - tryptophan biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_009501528.1
GO:0004834 - tryptophan synthase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011279732.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279733.1
acetyl-CoA carboxylase, carboxyltransferase subunit beta
COORDINATES: similar to AA sequence:RefSeq:WP_020442799.1
bifunctional folylpolyglutamate synthase/dihydrofolate synthase
This domain is about 40 residues long and is found in a variety of enzymes involved in bacterial cell wall degradation.
COORDINATES: similar to AA sequence:RefSeq:WP_020442800.1
LysM peptidoglycan-binding domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_020442801.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512841.1
COORDINATES: similar to AA sequence:RefSeq:WP_004716611.1
COORDINATES: similar to AA sequence:RefSeq:WP_003658428.1
COORDINATES: protein motif:HMM:NF025659.2
COORDINATES: protein motif:HMM:NF024939.2
COORDINATES: similar to AA sequence:RefSeq:WP_003664508.1
COORDINATES: similar to AA sequence:RefSeq:WP_005266831.1
COORDINATES: similar to AA sequence:RefSeq:WP_004720109.1
GO:0005198 - structural molecule activity [Evidence IEA]
GO:0016032 - viral process [Evidence IEA]
COORDINATES: protein motif:HMM:NF012307.2
COORDINATES: protein motif:HMM:NF017451.2
COORDINATES: similar to AA sequence:RefSeq:WP_019519892.1
COORDINATES: similar to AA sequence:RefSeq:WP_005257524.1
COORDINATES: similar to AA sequence:RefSeq:WP_003663121.1
COORDINATES: protein motif:HMM:NF022810.2
COORDINATES: protein motif:HMM:TIGR01725.1
COORDINATES: protein motif:HMM:NF017343.2
COORDINATES: similar to AA sequence:RefSeq:WP_016653724.1
COORDINATES: similar to AA sequence:RefSeq:WP_000128095.1
GO:0044423 - virion component [Evidence IEA]
GO:0019068 - virion assembly [Evidence IEA]
COORDINATES: protein motif:HMM:NF016471.2
GO:0008233 - peptidase activity [Evidence IEA]; GO:0005198 - structural molecule activity [Evidence IEA]
it forms the junction between the phage head (capsid) and the tail proteins
COORDINATES: protein motif:HMM:TIGR01537.1
Terminases cleave the cohesive ends of lambda family phage.
COORDINATES: protein motif:HMM:NF015321.2
COORDINATES: protein motif:HMM:TIGR01558.1
phage terminase small subunit P27 family
COORDINATES: protein motif:HMM:NF013964.2
HNH endonuclease signature motif containing protein
COORDINATES: protein motif:HMM:NF040238.1
COORDINATES: protein motif:HMM:NF019878.2
COORDINATES: protein motif:HMM:NF027273.2
COORDINATES: protein motif:HMM:NF012920.2
COORDINATES: similar to AA sequence:RefSeq:WP_020444027.1
TraR/DksA family transcriptional regulator
COORDINATES: protein motif:HMM:NF012798.2
-This enzyme functions as an alternative to a direct Gln-tRNA synthetase (Gln--tRNA ligase) in mitochondria, chloroplasts, gram-positive bacteria, cyanobacteria, and the Archaea.
COORDINATES: similar to AA sequence:RefSeq:WP_011279779.1
GO:0016884 - carbon-nitrogen ligase activity, with glutamine as amido-N-donor [Evidence IEA]
Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB
COORDINATES: similar to AA sequence:RefSeq:WP_011279780.1
GO:0030956 - glutamyl-tRNA(Gln) amidotransferase complex [Evidence IEA]
GO:0050567 - glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity [Evidence IEA]
GO:0006424 - glutamyl-tRNA aminoacylation [Evidence IEA]
Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA
COORDINATES: similar to AA sequence:RefSeq:WP_010196657.1
Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC
The role in Biosynthesis of murein sacculus and peptidoglycan
COORDINATES: similar to AA sequence:RefSeq:WP_010196659.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512847.1
GO:0008360 - regulation of cell shape [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020442810.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279785.1
COORDINATES: similar to AA sequence:RefSeq:WP_003656993.1
COORDINATES: similar to AA sequence:RefSeq:WP_014268624.1
GO:0003723 - RNA binding [Evidence IEA]; GO:0003735 - structural constituent of ribosome [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_005233737.1
COORDINATES: similar to AA sequence:RefSeq:WP_003656988.1
GO:0022625 - cytosolic large ribosomal subunit [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011279789.1
COORDINATES: similar to AA sequence:RefSeq:WP_003674247.1
GO:0022625 - cytosolic large ribosomal subunit [Evidence IEA]; GO:0000315 - organellar large ribosomal subunit [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:YP_004996805.1
COORDINATES: similar to AA sequence:RefSeq:WP_003656983.1
GO:0022625 - cytosolic large ribosomal subunit [Evidence IEA]; GO:0000311 - plastid large ribosomal subunit [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011512854.1
GO:0022627 - cytosolic small ribosomal subunit [Evidence IEA]; GO:0000312 - plastid small ribosomal subunit [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_017805229.1
COORDINATES: similar to AA sequence:RefSeq:WP_003656979.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512856.1
COORDINATES: similar to AA sequence:RefSeq:WP_012728338.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512857.1
COORDINATES: similar to AA sequence:RefSeq:YP_004996797.1
COORDINATES: similar to AA sequence:RefSeq:WP_004924130.1
COORDINATES: similar to AA sequence:RefSeq:WP_011148781.1
COORDINATES: similar to AA sequence:RefSeq:WP_016654891.1
GO:0019843 - rRNA binding [Evidence IEA]; GO:0003735 - structural constituent of ribosome [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:YP_004996793.1
COORDINATES: similar to AA sequence:RefSeq:WP_010196711.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279802.1
COORDINATES: similar to AA sequence:RefSeq:WP_005012960.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512863.1
COORDINATES: similar to AA sequence:RefSeq:WP_020322760.1
COORDINATES: similar to AA sequence:RefSeq:YP_004996787.1
GO:0022627 - cytosolic small ribosomal subunit [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_001029758.1
COORDINATES: similar to AA sequence:RefSeq:WP_004924159.1
GO:0015935 - small ribosomal subunit [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:YP_004996784.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0003899 - DNA-directed 5'-3' RNA polymerase activity [Evidence IEA]; GO:0046983 - protein dimerization activity [Evidence IEA]
GO:0006351 - DNA-templated transcription [Evidence IEA]
DNA-directed RNA polymerase subunit alpha
COORDINATES: similar to AA sequence:RefSeq:WP_011959733.1
GO:0022625 - cytosolic large ribosomal subunit [Evidence IEA]; GO:0005762 - mitochondrial large ribosomal subunit [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020442814.1
GO:0061710 - L-threonylcarbamoyladenylate synthase [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020442815.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279812.1
COORDINATES: similar to AA sequence:RefSeq:WP_003656952.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279814.1
GO:0004314 - [acyl-carrier-protein] S-malonyltransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_003653349.1
GO:0004316 - 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity [Evidence IEA]; GO:0051287 - NAD binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010196746.1
COORDINATES: similar to AA sequence:RefSeq:WP_004881155.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442818.1
GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; GO:0052693 - epoxyqueuosine reductase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010196757.1
GO:0052855 - ADP-dependent NAD(P)H-hydrate dehydratase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010196759.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512876.1
GO:0003984 - acetolactate synthase activity [Evidence IEA]; GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; GO:0000287 - magnesium ion binding [Evidence IEA]; GO:0030976 - thiamine pyrophosphate binding [Evidence IEA]
GO:0009082 - branched-chain amino acid biosynthetic process [Evidence IEA]
Biosynthesis of pantothenate and CoA; Metabolism of amino acids
COORDINATES: similar to AA sequence:RefSeq:WP_011512877.1
GO:1990610 - acetolactate synthase regulator activity [Evidence IEA]
Biosynthesis of pantothenate and CoA; Synthesis of branched chain amino acids
COORDINATES: similar to AA sequence:RefSeq:YP_004997723.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512879.1
COORDINATES: similar to AA sequence:RefSeq:WP_000106983.1
COORDINATES: similar to AA sequence:RefSeq:WP_016140229.1
electron transfer flavoprotein subunit beta/FixA family protein
COORDINATES: similar to AA sequence:RefSeq:WP_003659004.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280162.1
COORDINATES: protein motif:HMM:NF015431.2
LysR family transcriptional regulator substrate-binding protein
COORDINATES: protein motif:HMM:NF013677.2
COORDINATES: similar to AA sequence:RefSeq:WP_076612109.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442824.1
COORDINATES: similar to AA sequence:RefSeq:WP_010196809.1
GO:0042132 - fructose 1,6-bisphosphate 1-phosphatase activity [Evidence IEA]
'de novo' Pyrimidine biosynthesis, Aspartate metabolism
COORDINATES: similar to AA sequence:RefSeq:WP_011512884.1
GO:0016597 - amino acid binding [Evidence IEA]; GO:0004070 - aspartate carbamoyltransferase activity [Evidence IEA]
GO:0006207 - 'de novo' pyrimidine nucleobase biosynthetic process [Evidence IEA]; GO:0006520 - amino acid metabolic process [Evidence IEA]
aspartate carbamoyltransferase catalytic subunit
COORDINATES: similar to AA sequence:RefSeq:WP_010196814.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512886.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512887.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512888.1
COORDINATES: similar to AA sequence:RefSeq:WP_010196827.1
regulation of transcription: involved in the biosynthesis and uptake of the amino acid tryptophan
COORDINATES: similar to AA sequence:RefSeq:WP_011279839.1
GO:0010181 - FMN binding [Evidence IEA]; GO:0003955 - NAD(P)H dehydrogenase (quinone) activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020442832.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512892.1
COORDINATES: similar to AA sequence:RefSeq:WP_005144860.1
COORDINATES: similar to AA sequence:RefSeq:WP_011959918.1
GO:0016887 - ATP hydrolysis activity [Evidence IEA]; GO:0005515 - protein binding [Evidence IEA]
GO:0006457 - protein folding [Evidence IEA]
60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_011279844.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442836.1
GO:0008746 - NAD(P)+ transhydrogenase activity [Evidence IEA]
GO:1902600 - proton transmembrane transport [Evidence IEA]
Re/Si-specific NAD(P)(+) transhydrogenase subunit alpha
COORDINATES: similar to AA sequence:RefSeq:WP_016657443.1
proton-translocating transhydrogenase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_007394004.1
NAD(P)(+) transhydrogenase (Re/Si-specific) subunit beta
COORDINATES: similar to AA sequence:RefSeq:WP_020442839.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279849.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512899.1
Diaminopimellate biosynthesis, Lysine biosynthesis
COORDINATES: similar to AA sequence:RefSeq:WP_007116654.1
GO:0009014 - succinyl-diaminopimelate desuccinylase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011512901.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512902.1
GO:0008649 - rRNA methyltransferase activity [Evidence IEA]
GO:0070475 - rRNA base methylation [Evidence IEA]
23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ
COORDINATES: similar to AA sequence:RefSeq:WP_020442844.1
GO:0003882 - CDP-diacylglycerol-serine O-phosphatidyltransferase activity [Evidence IEA]
CDP-diacylglycerol--serine O-phosphatidyltransferase
COORDINATES: nucleotide motif:Rfam:14.4:RF00177
COORDINATES: nucleotide motif:Rfam:14.4:RF02541
COORDINATES: nucleotide motif:Rfam:14.4:RF00001
COORDINATES: similar to AA sequence:RefSeq:WP_004814543.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279856.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442849.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442850.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512910.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442852.1
GO:0004096 - catalase activity [Evidence IEA]; GO:0020037 - heme binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020442853.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512913.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442855.1
efflux RND transporter periplasmic adaptor subunit
DNA polymerase III, delta subunit is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalysed reaction.
COORDINATES: similar to AA sequence:RefSeq:WP_011279864.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279865.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442858.1
GO:0004823 - leucine-tRNA ligase activity [Evidence IEA]
GO:0006429 - leucyl-tRNA aminoacylation [Evidence IEA]
COORDINATES: protein motif:HMM:NF017539.2
COORDINATES: similar to AA sequence:RefSeq:WP_020442859.1
Spx/MgsR family RNA polymerase-binding regulatory protein
COORDINATES: similar to AA sequence:RefSeq:WP_007395483.1
GO:0003991 - acetylglutamate kinase activity [Evidence IEA]
GO:0006592 - ornithine biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020442862.1
Pyrimidine metabolism: Cleaves dUTP into dUMP and pyrophosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_011512921.1
GO:0004170 - dUTP diphosphatase activity [Evidence IEA]; GO:0000287 - magnesium ion binding [Evidence IEA]
GO:0006226 - dUMP biosynthetic process [Evidence IEA]; GO:0046081 - dUTP catabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011512922.1
GO:0015095 - magnesium ion transmembrane transporter activity [Evidence IEA]
GO:0015693 - magnesium ion transport [Evidence IEA]
Members of this family are helicases that catalyse ATP dependent unwinding of double stranded DNA to single stranded DNA. The family includes both Rep and UvrD helcases. UvrD functions in nucleotide excision repair.
COORDINATES: similar to AA sequence:RefSeq:WP_011279872.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512924.1
GO:0008137 - NADH dehydrogenase (ubiquinone) activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_000386733.1
COORDINATES: similar to AA sequence:RefSeq:WP_010198896.1
GO:0030964 - NADH dehydrogenase complex [Evidence IEA]
GO:0051287 - NAD binding [Evidence IEA]; GO:0050136 - NADH dehydrogenase (quinone) activity [Evidence IEA]; GO:0048038 - quinone binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011512927.1
NADH-quinone oxidoreductase subunit NuoE
COORDINATES: similar to AA sequence:RefSeq:WP_011512928.1
GO:0050136 - NADH dehydrogenase (quinone) activity [Evidence IEA]
NADH-quinone oxidoreductase subunit NuoF
COORDINATES: similar to AA sequence:RefSeq:WP_011512929.1
GO:0006120 - mitochondrial electron transport, NADH to ubiquinone [Evidence IEA]
NADH-quinone oxidoreductase subunit NuoG
COORDINATES: similar to AA sequence:RefSeq:WP_010198901.1
NADH-quinone oxidoreductase subunit NuoH
COORDINATES: similar to AA sequence:RefSeq:WP_013107845.1
GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; GO:0016651 - oxidoreductase activity, acting on NAD(P)H [Evidence IEA]
NADH-quinone oxidoreductase subunit NuoI
COORDINATES: similar to AA sequence:RefSeq:WP_011512932.1
COORDINATES: similar to AA sequence:RefSeq:WP_004922503.1
GO:0016651 - oxidoreductase activity, acting on NAD(P)H [Evidence IEA]
GO:0042773 - ATP synthesis coupled electron transport [Evidence IEA]
NADH-quinone oxidoreductase subunit NuoK
COORDINATES: similar to AA sequence:RefSeq:WP_003668641.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279884.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512936.1
COORDINATES: similar to AA sequence:RefSeq:WP_003659474.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512938.1
COORDINATES: similar to AA sequence:RefSeq:WP_003663968.1
COORDINATES: similar to AA sequence:RefSeq:WP_007393970.1
GO:0022857 - transmembrane transporter activity [Evidence IEA]
GO:0055085 - transmembrane transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_005403891.1
two-component system response regulator NarL
COORDINATES: similar to AA sequence:RefSeq:WP_005403892.1
GO:0000155 - phosphorelay sensor kinase activity [Evidence IEA]; GO:0046983 - protein dimerization activity [Evidence IEA]
GO:0000160 - phosphorelay signal transduction system [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_005403893.1
GO:0015514 - nitrite efflux transmembrane transporter activity [Evidence IEA]
GO:0015707 - nitrite transport [Evidence IEA]
NarK family nitrate/nitrite MFS transporter
COORDINATES: similar to AA sequence:RefSeq:WP_005403894.1
GO:0009325 - nitrate reductase complex [Evidence IEA]
GO:0008940 - nitrate reductase activity [Evidence IEA]
GO:0009061 - anaerobic respiration [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011279895.1
COORDINATES: similar to AA sequence:RefSeq:WP_005403896.1
GO:0051082 - unfolded protein binding [Evidence IEA]
GO:0051131 - chaperone-mediated protein complex assembly [Evidence IEA]
nitrate reductase molybdenum cofactor assembly chaperone
COORDINATES: similar to AA sequence:RefSeq:WP_011959948.1
GO:0019645 - anaerobic electron transport chain [Evidence IEA]
respiratory nitrate reductase subunit gamma
COORDINATES: similar to AA sequence:RefSeq:WP_005403898.1
COORDINATES: similar to AA sequence:RefSeq:WP_005403899.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513062.1
GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]
GO:0006777 - Mo-molybdopterin cofactor biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011279901.1
molybdenum cofactor biosynthesis protein B
COORDINATES: similar to AA sequence:RefSeq:WP_011513060.1
NTP transferase domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_005403903.1
cyclic pyranopterin monophosphate synthase MoaC
COORDINATES: similar to AA sequence:RefSeq:WP_005403904.1
COORDINATES: similar to AA sequence:RefSeq:WP_011959515.1
molybdenum cofactor biosynthesis protein MoaE
COORDINATES: similar to AA sequence:RefSeq:WP_011513056.1
GO:0055052 - ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [Evidence IEA]; GO:0009897 - external side of plasma membrane [Evidence IEA]; GO:0030288 - outer membrane-bounded periplasmic space [Evidence IEA]
GO:0015412 - ABC-type molybdate transporter activity [Evidence IEA]; GO:0030973 - molybdate ion binding [Evidence IEA]
GO:0015689 - molybdate ion transport [Evidence IEA]
molybdate ABC transporter substrate-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_011513055.1
GO:0015412 - ABC-type molybdate transporter activity [Evidence IEA]
molybdate ABC transporter permease subunit
COORDINATES: similar to AA sequence:RefSeq:WP_005403906.1
COORDINATES: similar to AA sequence:RefSeq:WP_007393939.1
COORDINATES: protein motif:HMM:NF033664.1
COORDINATES: similar to AA sequence:RefSeq:WP_010201018.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442879.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512940.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279914.1
GO:0046872 - metal ion binding [Evidence IEA]; GO:0004540 - ribonuclease activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011961184.1
COORDINATES: similar to AA sequence:RefSeq:WP_010198936.1
UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase
COORDINATES: similar to AA sequence:RefSeq:WP_011512944.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512949.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512950.1
GO:0008734 - L-aspartate oxidase activity [Evidence IEA]
GO:0019363 - pyridine nucleotide biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011512951.1
GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; GO:0008987 - quinolinate synthetase A activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011512952.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279922.1
GO:0004514 - nicotinate-nucleotide diphosphorylase (carboxylating) activity [Evidence IEA]
carboxylating nicotinate-nucleotide diphosphorylase
COORDINATES: similar to AA sequence:RefSeq:WP_003658280.1
COORDINATES: similar to AA sequence:RefSeq:WP_011512955.1
GO:0006865 - amino acid transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_076611588.1
COORDINATES: similar to AA sequence:RefSeq:WP_004782642.1
COORDINATES: similar to AA sequence:RefSeq:WP_000915539.1
GO:0000271 - polysaccharide biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_000868810.1
COORDINATES: protein motif:HMM:NF040307.1
COORDINATES: similar to AA sequence:RefSeq:WP_076611943.1
programmed frameshift; internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_011279932.1
23S rRNA pseudouridine(2605) synthase RluB
COORDINATES: similar to AA sequence:RefSeq:WP_019673921.1
GO:0015159 - polysaccharide transmembrane transporter activity [Evidence IEA]
GO:0015774 - polysaccharide transport [Evidence IEA]
polysaccharide biosynthesis/export family protein
COORDINATES: similar to AA sequence:RefSeq:WP_020442896.1
low molecular weight phosphotyrosine protein phosphatase
COORDINATES: similar to AA sequence:RefSeq:WP_011512962.1
GO:0045226 - extracellular polysaccharide biosynthetic process [Evidence IEA]
polysaccharide biosynthesis tyrosine autokinase
COORDINATES: similar to AA sequence:RefSeq:WP_001175096.1
GO:0051287 - NAD binding [Evidence IEA]; GO:0016491 - oxidoreductase activity [Evidence IEA]
Vi polysaccharide biosynthesis UDP-N-acetylglucosamine C-6 dehydrogenase TviB
COORDINATES: similar to AA sequence:RefSeq:WP_005094743.1
NAD-dependent epimerase/dehydratase family protein
possible role in polysaccharide or protein efflux see J Bacteriol. 1990 Jun;172(6):3131-7.
COORDINATES: similar to AA sequence:RefSeq:WP_007394434.1
COORDINATES: similar to AA sequence:RefSeq:WP_004644021.1
UDP-N-acetylglucosamine 4,6-dehydratase (inverting)
COORDINATES: similar to AA sequence:RefSeq:WP_016542504.1
UDP-4-amino-4, 6-dideoxy-N-acetyl-beta-L-altrosamine transaminase
COORDINATES: protein motif:HMM:NF012745.2
Acylneuraminate cytidylyltransferase catalyzes the reaction of CTP and NeuAc to form CMP-NeuAc, which is the nucleotide sugar donor used by sialyltransferases. The outer membrane lipooligosaccharides of some microorganisms contain terminal
COORDINATES: similar to AA sequence:RefSeq:WP_004644018.1
GO:0070567 - cytidylyltransferase activity [Evidence IEA]
COORDINATES: protein motif:HMM:TIGR03590.1
GO:0016758 - hexosyltransferase activity [Evidence IEA]
UDP-2,4-diacetamido-2,4, 6-trideoxy-beta-L-altropyranose hydrolase
COORDINATES: protein motif:HMM:TIGR03585.1
GO:0008080 - N-acetyltransferase activity [Evidence IEA]
UDP-4-amino-4, 6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase
Catalyzes reaction: L-Methionyl-tRNA + 10-Formyltetrahydrofolate <=> Tetrahydrofolate + N-Formylmethionyl-tRNA
N-acetylneuraminic acid (Neu5Ac) synthase. It catalyses the direct formation of Neu5Ac (the most common sialic acid) by condensation of phosphoenolpyruvate (PEP) and N-acetylmannosamine (ManNAc).
COORDINATES: similar to AA sequence:RefSeq:WP_002069716.1
GO:0016765 - transferase activity, transferring alkyl or aryl (other than methyl) groups [Evidence IEA]
from Interpro: Although most of the proteins in this group are of unknown function one, from Schizosaccharomyces pombe, has been characterised as a probable N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase.
COORDINATES: protein motif:HMM:NF014625.2
COORDINATES: similar to AA sequence:RefSeq:WP_005124921.1
GO:0016051 - carbohydrate biosynthetic process [Evidence IEA]
N-acetylneuraminate synthase family protein
COORDINATES: protein motif:HMM:NF019535.2
COORDINATES: protein motif:HMM:NF024831.2
Asparagine biosynthesis, Glutamine -> Glutamate
COORDINATES: protein motif:HMM:TIGR01536.1
GO:0004066 - asparagine synthase (glutamine-hydrolyzing) activity [Evidence IEA]
GO:0006529 - asparagine biosynthetic process [Evidence IEA]
asparagine synthase (glutamine-hydrolyzing)
The biosynthesis of disaccharides, oligosaccharides and polysaccharides involves the action of hundreds of different glycosyltransferases
COORDINATES: protein motif:HMM:NF012744.2
COORDINATES: similar to AA sequence:RefSeq:WP_020442917.1
COORDINATES: similar to AA sequence:RefSeq:WP_011959528.1
COORDINATES: protein motif:HMM:NF014453.2
The integral inner-membrane proteins translocate the substrate across the membrane.
COORDINATES: similar to AA sequence:RefSeq:WP_019674125.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279959.1
bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD
COORDINATES: similar to AA sequence:RefSeq:WP_020442919.1
GO:0015087 - cobalt ion transmembrane transporter activity [Evidence IEA]; GO:0015095 - magnesium ion transmembrane transporter activity [Evidence IEA]
GO:0006824 - cobalt ion transport [Evidence IEA]; GO:0015693 - magnesium ion transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011512994.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442920.1
ATP phosphoribosyltransferase regulatory subunit
Purine biosynthesis: synthesis of AMP from IMP.
COORDINATES: similar to AA sequence:RefSeq:WP_004989707.1
GO:0004019 - adenylosuccinate synthase activity [Evidence IEA]; GO:0005525 - GTP binding [Evidence IEA]
Phosphorylation of GDP, CDP, and UDP and dTDP
COORDINATES: similar to AA sequence:RefSeq:WP_000963851.1
GO:0004550 - nucleoside diphosphate kinase activity [Evidence IEA]
GO:0006165 - nucleoside diphosphate phosphorylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011279965.1
GO:0016433 - rRNA (adenine) methyltransferase activity [Evidence IEA]; GO:0008757 - S-adenosylmethionine-dependent methyltransferase activity [Evidence IEA]
GO:0031167 - rRNA methylation [Evidence IEA]
23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN
COORDINATES: similar to AA sequence:RefSeq:WP_010199028.1
type IV pilus biogenesis/stability protein PilW
COORDINATES: similar to AA sequence:RefSeq:WP_020442925.1
COORDINATES: similar to AA sequence:RefSeq:WP_011279968.1
GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity [Evidence IEA]
GO:0044237 - cellular metabolic process [Evidence IEA]
flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase
COORDINATES: similar to AA sequence:RefSeq:WP_020442926.1
GO:0004821 - histidine-tRNA ligase activity [Evidence IEA]
GO:0006427 - histidyl-tRNA aminoacylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513004.1
COORDINATES: similar to AA sequence:RefSeq:WP_010199033.1
GO:0009279 - cell outer membrane [Evidence IEA]
outer membrane protein assembly factor BamB
COORDINATES: similar to AA sequence:RefSeq:WP_011279972.1
COORDINATES: similar to AA sequence:RefSeq:WP_010199038.1
D-alanyl-D-alanine carboxypeptidase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_011279974.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513010.1
incomplete; partial in the middle of a contig; missing N-terminus and C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
Probably involved in the cleavage of amino acids, specifically glycine bonds. They lyse the cell walls of Gram-positive bacteria
COORDINATES: similar to AA sequence:RefSeq:WP_011513011.1
peptidoglycan DD-metalloendopeptidase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_011513012.1
possible UDP-2,3-diacylglucosamine hydrolase
COORDINATES: similar to AA sequence:RefSeq:WP_011513013.1
GO:0016462 - pyrophosphatase activity [Evidence IEA]
GO:0009245 - lipid A biosynthetic process [Evidence IEA]
PPIase is an enzyme that accelerates protein folding by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides PUB00005503. (from PFAM)
COORDINATES: similar to AA sequence:RefSeq:WP_020442935.1
Catalysis of the attachment of an amino acid to its cognate transfer RNA molecule
COORDINATES: similar to AA sequence:RefSeq:WP_011279980.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0004819 - glutamine-tRNA ligase activity [Evidence IEA]; GO:0000166 - nucleotide binding [Evidence IEA]
GO:0006425 - glutaminyl-tRNA aminoacylation [Evidence IEA]
glutamine--tRNA ligase/YqeY domain fusion protein
COORDINATES: similar to AA sequence:RefSeq:WP_011513016.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513017.1
GO:0051920 - peroxiredoxin activity [Evidence IEA]; GO:0008379 - thioredoxin peroxidase activity [Evidence IEA]
GO:0098869 - cellular oxidant detoxification [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513018.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513020.1
Endonuclease that resolves Holliday junction intermediates in genetic recombination. The active form of the protein is a dimer.
COORDINATES: similar to AA sequence:RefSeq:WP_011513021.1
GO:0008821 - crossover junction endodeoxyribonuclease activity [Evidence IEA]
crossover junction endodeoxyribonuclease RuvC
COORDINATES: similar to AA sequence:RefSeq:WP_003663175.1
COORDINATES: nucleotide motif:Rfam:14.4:RF00013
COORDINATES: similar to AA sequence:RefSeq:WP_011279987.1
GO:0046537 - 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity [Evidence IEA]
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
COORDINATES: similar to AA sequence:RefSeq:WP_011513024.1
COORDINATES: protein motif:HMM:NF014950.2
This sequence contains both a regulatory protein domain and a response regulator domain
COORDINATES: similar to AA sequence:RefSeq:WP_019457005.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513028.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442945.1
PGK is an enzyme that catalyzes the formation of ATP to ADP and vice versa.
COORDINATES: similar to AA sequence:RefSeq:WP_011513031.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442948.1
Involved in glycolysis. Catalyses reversible aldol cleavage or condensation of fructose-1,6-bisphosphate into dihydroxyacetone-phosphate and glyceraldehyde 3-phosphate.
COORDINATES: similar to AA sequence:RefSeq:YP_004995203.1
catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis, and/or gluconeogenesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
RuvA forms a complex with RuvB, this complex is a helicase that mediates the Holliday junction migration by localised denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
COORDINATES: similar to AA sequence:RefSeq:WP_011513034.1
GO:0009379 - Holliday junction helicase complex [Evidence IEA]
GO:0009378 - four-way junction helicase activity [Evidence IEA]
Holliday junction branch migration protein RuvA
COORDINATES: similar to AA sequence:RefSeq:WP_010199300.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0003677 - DNA binding [Evidence IEA]; GO:0009378 - four-way junction helicase activity [Evidence IEA]
Holliday junction branch migration DNA helicase RuvB
COORDINATES: similar to AA sequence:RefSeq:WP_010199302.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442953.1
COORDINATES: similar to AA sequence:RefSeq:WP_010199307.1
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE
COORDINATES: similar to AA sequence:RefSeq:WP_020442955.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442956.1
COORDINATES: similar to AA sequence:RefSeq:WP_020442957.1
COORDINATES: similar to AA sequence:RefSeq:WP_009767509.1
aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme
COORDINATES: protein motif:HMM:NF024252.2
COORDINATES: similar to AA sequence:RefSeq:WP_020442960.1
GO:0033743 - peptide-methionine (R)-S-oxide reductase activity [Evidence IEA]
GO:0030091 - protein repair [Evidence IEA]; GO:0006979 - response to oxidative stress [Evidence IEA]
peptide-methionine (R)-S-oxide reductase MsrB
COORDINATES: similar to AA sequence:RefSeq:WP_020443906.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443905.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443904.1
frameshifted; internal stop; incomplete; partial in the middle of a contig; missing C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: protein motif:HMM:NF023295.2
COORDINATES: similar to AA sequence:RefSeq:WP_076612165.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280008.1
GO:0071705 - nitrogen compound transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020443151.1
GO:0008812 - choline dehydrogenase activity [Evidence IEA]
GO:0019285 - glycine betaine biosynthetic process from choline [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_005218139.1
GO:0008802 - betaine-aldehyde dehydrogenase activity [Evidence IEA]; GO:0046872 - metal ion binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513214.1
TetR/AcrR family transcriptional regulator
COORDINATES: similar to AA sequence:RefSeq:WP_011513213.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280013.1
All proteins in this family are 5'-3' single-strand DNA exonucleases. These proteins are used in some aspects of mismatch repair, recombination, and recombinational repair.
COORDINATES: similar to AA sequence:RefSeq:WP_020443022.1
GO:0008297 - single-stranded DNA exodeoxyribonuclease activity [Evidence IEA]
single-stranded-DNA-specific exonuclease RecJ
COORDINATES: similar to AA sequence:RefSeq:WP_011513071.1
trimeric intracellular cation channel family protein
COORDINATES: similar to AA sequence:RefSeq:WP_011513073.1
multidrug resistance efflux transporter family protein
COORDINATES: similar to AA sequence:RefSeq:WP_011513074.1
GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; GO:1904047 - S-adenosyl-L-methionine binding [Evidence IEA]
Lysine biosynthesis via the diaminopimellate pathway, Diaminopimellate biosynthesis
COORDINATES: similar to AA sequence:RefSeq:WP_011960167.1
GO:0008666 - 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity [Evidence IEA]
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_020443028.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443031.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443032.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280022.1
cyclopropane-fatty-acyl-phospholipid synthase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_011513081.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513082.1
UvrB is a DNA helicase that functions in the nucleotide excision repair and is an endonuclease that make the 3' incision next to DNA damage. They are part of a pathway requiring UvrA, UvrB, UvrC, and UvrD homologs.
COORDINATES: similar to AA sequence:RefSeq:WP_011280025.1
GO:0009380 - excinuclease repair complex [Evidence IEA]
GO:0005524 - ATP binding [Evidence IEA]; GO:0016887 - ATP hydrolysis activity [Evidence IEA]; GO:0003677 - DNA binding [Evidence IEA]; GO:0016787 - hydrolase activity [Evidence IEA]; GO:0005515 - protein binding [Evidence IEA]
GO:0006289 - nucleotide-excision repair [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513090.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513091.1
TAXI family TRAP transporter solute-binding subunit
COORDINATES: similar to AA sequence:RefSeq:WP_020443041.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443042.1
COORDINATES: similar to AA sequence:RefSeq:WP_019673081.1
GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; GO:0016992 - lipoate synthase activity [Evidence IEA]; GO:1904047 - S-adenosyl-L-methionine binding [Evidence IEA]
GO:0009107 - lipoate biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513095.1
GO:0051920 - peroxiredoxin activity [Evidence IEA]
carboxymuconolactone decarboxylase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_003658993.1
GO:0003994 - aconitate hydratase activity [Evidence IEA]
bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase
COORDINATES: protein motif:HMM:NF025056.2
toll/interleukin-1 receptor domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_020443046.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443048.1
HpcH/HpaI aldolase/citrate lyase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_011513101.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443050.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443055.1
phosphoribosyltransferase domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_020443056.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443057.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513115.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513116.1
COORDINATES: similar to AA sequence:RefSeq:WP_003976436.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513117.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443061.1
GO:0003723 - RNA binding [Evidence IEA]; GO:0008990 - rRNA (guanine-N2-)-methyltransferase activity [Evidence IEA]
bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL
COORDINATES: similar to AA sequence:RefSeq:WP_020443062.1
mechanosensitive ion channel family protein
COORDINATES: similar to AA sequence:RefSeq:WP_011513121.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443064.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513123.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513124.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280052.1
GO:0008033 - tRNA processing [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513126.1
COORDINATES: similar to AA sequence:RefSeq:WP_010199601.1
GO:0008535 - respiratory chain complex IV assembly [Evidence IEA]
cytochrome c oxidase accessory protein CcoG
COORDINATES: similar to AA sequence:RefSeq:WP_011513128.1
GO:0004129 - cytochrome-c oxidase activity [Evidence IEA]
cytochrome-c oxidase, cbb3-type subunit III
COORDINATES: similar to AA sequence:RefSeq:WP_011513129.1
CcoQ/FixQ family Cbb3-type cytochrome c oxidase assembly chaperone
COORDINATES: similar to AA sequence:RefSeq:WP_007395385.1
cytochrome-c oxidase, cbb3-type subunit II
COORDINATES: similar to AA sequence:RefSeq:WP_011513131.1
cytochrome-c oxidase, cbb3-type subunit I
COORDINATES: similar to AA sequence:RefSeq:WP_010199611.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280060.1
COORDINATES: similar to AA sequence:RefSeq:WP_004878461.1
GO:0042953 - lipoprotein transport [Evidence IEA]
lipoprotein-releasing ABC transporter permease subunit
COORDINATES: similar to AA sequence:RefSeq:WP_011513135.1
GO:0043190 - ATP-binding cassette (ABC) transporter complex [Evidence IEA]
lipoprotein-releasing ABC transporter ATP-binding protein LolD
COORDINATES: similar to AA sequence:RefSeq:WP_011513136.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513137.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443075.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513139.1
GO:0006465 - signal peptide processing [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513140.1
COORDINATES: similar to AA sequence:RefSeq:WP_068036561.1
CPBP family intramembrane metalloprotease
COORDINATES: similar to AA sequence:RefSeq:WP_010199634.1
GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; GO:0017150 - tRNA dihydrouridine synthase activity [Evidence IEA]
GO:0002943 - tRNA dihydrouridine synthesis [Evidence IEA]
tRNA dihydrouridine(20/20a) synthase DusA
COORDINATES: similar to AA sequence:RefSeq:WP_011513143.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443080.1
Methionine biosynthesis: Interconverts O-succinyl-L-homoserine -> cystithione -> O-acetylhomoserine -> homocysteine
COORDINATES: similar to AA sequence:RefSeq:WP_010199652.1
GO:0003824 - catalytic activity [Evidence IEA]; GO:0030170 - pyridoxal phosphate binding [Evidence IEA]
GO:0071268 - homocysteine biosynthetic process [Evidence IEA]; GO:0019346 - transsulfuration [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011280073.1
YbaB/EbfC family nucleoid-associated protein
All proteins in this family for which functions are known are involved in the initiation of recombination and recombinational repair. RecF is also required.
COORDINATES: similar to AA sequence:RefSeq:WP_011280074.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443083.1
Glycine metabolism, Glycine cleavage system
COORDINATES: similar to AA sequence:RefSeq:WP_020443085.1
GO:0004375 - glycine dehydrogenase (decarboxylating) activity [Evidence IEA]
GO:0019464 - glycine decarboxylation via glycine cleavage system [Evidence IEA]
aminomethyl-transferring glycine dehydrogenase
COORDINATES: similar to AA sequence:RefSeq:WP_020443086.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280078.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443087.1
GO:0004047 - aminomethyltransferase activity [Evidence IEA]
glycine cleavage system aminomethyltransferase GcvT
COORDINATES: nucleotide motif:Rfam:14.4:RF00504
glycine riboswitch; Derived by automated computational analysis using gene prediction method: cmsearch.
COORDINATES: similar to AA sequence:RefSeq:WP_011280080.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443089.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513155.1
COORDINATES: similar to AA sequence:RefSeq:WP_009393405.1
COORDINATES: similar to AA sequence:RefSeq:WP_009519721.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513160.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443096.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280086.1
CaiB/BaiF CoA-transferase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_011513163.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443098.1
NAD-dependent succinate-semialdehyde dehydrogenase
Glutamate metabolism, Alanine and Aspartate metabolism, beta-Alanine metabolism, Propionate metabolism, Butanoate metabolism
COORDINATES: similar to AA sequence:RefSeq:WP_020443099.1
GO:0003867 - 4-aminobutyrate transaminase activity [Evidence IEA]
GO:0009450 - gamma-aminobutyric acid catabolic process [Evidence IEA]
4-aminobutyrate--2-oxoglutarate transaminase
COORDINATES: similar to AA sequence:RefSeq:WP_020443100.1
COORDINATES: similar to AA sequence:RefSeq:WP_010198668.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443112.1
ndogenous, endonucleolytic transcript cleavage activity of the RNA polymerase (RNAP), allowing RNA transcription to continue past template-encoded arresting sites.
COORDINATES: similar to AA sequence:RefSeq:WP_010198674.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0070063 - RNA polymerase binding [Evidence IEA]
GO:0032784 - regulation of DNA-templated transcription elongation [Evidence IEA]
Pyrimindine biosynthesis, Arginine biosynthesis
COORDINATES: similar to AA sequence:RefSeq:WP_020443113.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0046872 - metal ion binding [Evidence IEA]
GO:0006807 - nitrogen compound metabolic process [Evidence IEA]
carbamoyl-phosphate synthase large subunit
Pyrimidine biosynthesis, Arginine biosynthesis
COORDINATES: similar to AA sequence:RefSeq:WP_020443114.1
GO:0005951 - carbamoyl-phosphate synthase complex [Evidence IEA]
GO:0004088 - carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity [Evidence IEA]
GO:0009220 - pyrimidine ribonucleotide biosynthetic process [Evidence IEA]
glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit
COORDINATES: similar to AA sequence:RefSeq:WP_011513177.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443115.1
COORDINATES: similar to AA sequence:RefSeq:WP_009502185.1
COORDINATES: similar to AA sequence:RefSeq:WP_131667308.1
GO:0003747 - translation release factor activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513181.1
COORDINATES: similar to AA sequence:RefSeq:WP_076612107.1
COORDINATES: similar to AA sequence:RefSeq:WP_010198701.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513185.1
SDR family NAD(P)-dependent oxidoreductase
COORDINATES: similar to AA sequence:RefSeq:WP_001210049.1
COORDINATES: protein motif:HMM:NF019607.2
frameshifted; incomplete; partial in the middle of a contig; missing C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_011513189.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513191.1
COORDINATES: similar to AA sequence:RefSeq:WP_020753076.1
GO:0004478 - methionine adenosyltransferase activity [Evidence IEA]
GO:0006556 - S-adenosylmethionine biosynthetic process [Evidence IEA]
Endonuclease III is a DNA repair enzyme which removes a number of damaged pyrimidines from DNA via its glycosylase activity and also cleaves the phosphodiester backbone at apurinic/ apyrimidinic sites via a beta-elimination mechanism.
COORDINATES: similar to AA sequence:RefSeq:WP_010196146.1
GO:0003906 - DNA-(apurinic or apyrimidinic site) endonuclease activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020443131.1
GO:0009055 - electron transfer activity [Evidence IEA]; GO:0051536 - iron-sulfur cluster binding [Evidence IEA]
GO:0022900 - electron transport chain [Evidence IEA]
RnfABCDGE type electron transport complex subunit B
NUDIX hydrolases (NUcleoside DIphosphate linked to some other moiety X) can be divided into a number of subgroups. Most hydrolyse diverse nucleoside diphosphate derivatives (including ADP-ribose, GDP- mannose, TDP-glucose, NADH, UDP-sugars, dNTP and NTP).
COORDINATES: similar to AA sequence:RefSeq:WP_011513195.1
GO:0016787 - hydrolase activity [Evidence IEA]; GO:0000210 - NAD+ diphosphatase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010198519.1
The epsiolon subunit is responsible for the proofreading 3'-5' exonuclease activit of the DNA polymerase III core enzyme. The RNase H domain is responsible for hydrolysis of the RNA portion of RNA x DNA hybrids.
COORDINATES: similar to AA sequence:RefSeq:WP_020443134.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0003887 - DNA-directed DNA polymerase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020443135.1
COORDINATES: similar to AA sequence:RefSeq:WP_010196130.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513200.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443137.1
COORDINATES: similar to AA sequence:RefSeq:WP_010198548.1
alternative ribosome rescue aminoacyl-tRNA hydrolase ArfB
COORDINATES: similar to AA sequence:RefSeq:WP_011513210.1
ChrR is sufficient to inhibit sigma(E)-dependent transcription. Inhibition is proposed to proceed through a binding interaction, since sigma(E) and ChrR form a 1:1 complex that can be purified when expressed at high levels in Escherichia coli
COORDINATES: similar to AA sequence:RefSeq:WP_011513211.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443148.1
COORDINATES: similar to AA sequence:RefSeq:WP_010198609.1
COORDINATES: protein motif:HMM:NF014697.2
COORDINATES: similar to AA sequence:RefSeq:WP_020443164.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443175.1
COORDINATES: similar to AA sequence:RefSeq:WP_005008954.1
GO:0003871 - 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity [Evidence IEA]; GO:0008270 - zinc ion binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004894754.1
COORDINATES: similar to AA sequence:RefSeq:WP_005237608.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443179.1
part of a glucose utilization pathway whereby glucose is converted to pentose
COORDINATES: similar to AA sequence:RefSeq:WP_011513248.1
SMP-30/gluconolactonase/LRE family protein
COORDINATES: similar to AA sequence:RefSeq:WP_011513249.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280133.1
TRAP transporter substrate-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_011513250.1
23S rRNA pseudouridine(2604) synthase RluF
COORDINATES: similar to AA sequence:RefSeq:WP_008215675.1
COORDINATES: similar to AA sequence:RefSeq:WP_010199698.1
GO:0030976 - thiamine pyrophosphate binding [Evidence IEA]
COORDINATES: protein motif:HMM:NF023154.2
COORDINATES: similar to AA sequence:RefSeq:WP_020444574.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444575.1
COORDINATES: similar to AA sequence:RefSeq:WP_002061839.1
COORDINATES: similar to AA sequence:RefSeq:WP_004655753.1
COORDINATES: similar to AA sequence:RefSeq:WP_005198563.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513944.1
COORDINATES: similar to AA sequence:RefSeq:WP_004279319.1
COORDINATES: similar to AA sequence:RefSeq:WP_004279322.1
COORDINATES: similar to AA sequence:RefSeq:WP_004720118.1
lecithin retinol acyltransferase family protein
COORDINATES: protein motif:HMM:NF022607.2
Site-specific DNA-methyltransferase (adenine-specific) activity: part of the restriction-modification system.
COORDINATES: similar to AA sequence:RefSeq:WP_011280154.1
class I SAM-dependent DNA methyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_007393446.1
virulence protein RhuM/Fic/DOC family protein
COORDINATES: similar to AA sequence:RefSeq:WP_007393538.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280158.1
type I restriction endonuclease subunit R
COORDINATES: similar to AA sequence:RefSeq:WP_005245987.1
COORDINATES: similar to AA sequence:RefSeq:WP_004751244.1
COORDINATES: similar to AA sequence:RefSeq:WP_005172668.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513931.1
GO:0015074 - DNA integration [Evidence IEA]; GO:0006310 - DNA recombination [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_003659117.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443680.1
GO:0008757 - S-adenosylmethionine-dependent methyltransferase activity [Evidence IEA]
tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO
COORDINATES: similar to AA sequence:RefSeq:WP_020443679.1
COORDINATES: similar to AA sequence:RefSeq:WP_010199794.1
contains helix turn helix motif of several transcriptional regulators of TetR family not enough info for sub- family
COORDINATES: similar to AA sequence:RefSeq:WP_011513862.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513857.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513856.1
GO:0008832 - dGTPase activity [Evidence IEA]
GO:0006203 - dGTP catabolic process [Evidence IEA]
deoxyguanosinetriphosphate triphosphohydrolase
COORDINATES: similar to AA sequence:RefSeq:YP_004995132.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443671.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443669.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443236.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513851.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280175.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513849.1
GO:0050218 - propionate-CoA ligase activity [Evidence IEA]
GO:0019629 - propionate catabolic process, 2-methylcitrate cycle [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010201117.1
CoA-acylating methylmalonate-semialdehyde dehydrogenase
COORDINATES: similar to AA sequence:RefSeq:WP_011513847.1
GO:0016627 - oxidoreductase activity, acting on the CH-CH group of donors [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010201121.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443663.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443662.1
GO:0008442 - 3-hydroxyisobutyrate dehydrogenase activity [Evidence IEA]
GO:0006574 - valine catabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020443661.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513842.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513841.1
GO:0008897 - holo-[acyl-carrier-protein] synthase activity [Evidence IEA]; GO:0000287 - magnesium ion binding [Evidence IEA]
4'-phosphopantetheinyl transferase superfamily protein
COORDINATES: similar to AA sequence:RefSeq:WP_011513840.1
peptidoglycan-associated lipoprotein Pal
COORDINATES: similar to AA sequence:RefSeq:WP_010201130.1
GO:0004177 - aminopeptidase activity [Evidence IEA]; GO:0008237 - metallopeptidase activity [Evidence IEA]
Chorismate biosynthesis, aromatic amino acid biosynthesis
COORDINATES: similar to AA sequence:RefSeq:WP_011280187.1
GO:0003849 - 3-deoxy-7-phosphoheptulonate synthase activity [Evidence IEA]
GO:0009423 - chorismate biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513837.1
GO:0008915 - lipid-A-disaccharide synthase activity [Evidence IEA]
Ribonuclease HII is involved in the degradation of the ribonucleotide moiety on RNA-DNA hybrid molecules carrying out endonucleolytic cleavage to 5'-phospo-monoester.
COORDINATES: similar to AA sequence:RefSeq:WP_011280189.1
GO:0003723 - RNA binding [Evidence IEA]; GO:0004523 - RNA-DNA hybrid ribonuclease activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513833.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513832.1
saccharopine dehydrogenase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_011280192.1
PhzF family phenazine biosynthesis protein
COORDINATES: similar to AA sequence:RefSeq:WP_011280193.1
possible 6-pyruvoyl tetrahydropterin synthase
COORDINATES: similar to AA sequence:RefSeq:WP_010198104.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513827.1
tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE
COORDINATES: similar to AA sequence:RefSeq:WP_010198107.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443644.1
GO:0052381 - tRNA dimethylallyltransferase activity [Evidence IEA]
tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA
The bacterial Hfq protein is an abundant RNA-binding protein which modulates the stability or the translation of mRNAs and has recently been shown to interact with small regulatory RNAs in Escherichia coli. Hfq is involved also in the expression of many c
COORDINATES: similar to AA sequence:RefSeq:WP_020443643.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443642.1
GO:0016853 - isomerase activity [Evidence IEA]
KpsF/GutQ family sugar-phosphate isomerase
COORDINATES: similar to AA sequence:RefSeq:WP_011513822.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280201.1
LPS export ABC transporter periplasmic protein LptC
COORDINATES: similar to AA sequence:RefSeq:WP_009501237.1
GO:0043190 - ATP-binding cassette (ABC) transporter complex [Evidence IEA]; GO:0030288 - outer membrane-bounded periplasmic space [Evidence IEA]
GO:0001530 - lipopolysaccharide binding [Evidence IEA]
lipopolysaccharide transport periplasmic protein LptA
COORDINATES: similar to AA sequence:RefSeq:WP_019520109.1
GO:0043190 - ATP-binding cassette (ABC) transporter complex [Evidence IEA]; GO:0009898 - cytoplasmic side of plasma membrane [Evidence IEA]
GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]; GO:0015221 - lipopolysaccharide transmembrane transporter activity [Evidence IEA]
LPS export ABC transporter ATP-binding protein
RadA/Sms is involved in recombination and recombinational repair, most likely involving the stabilization or processing of branched DNA molecules or blocked replication forks because of its genetic redundancy with RecG and RuvABC.
COORDINATES: similar to AA sequence:RefSeq:WP_011513818.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280205.1
COORDINATES: similar to AA sequence:RefSeq:WP_010198122.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443637.1
D-Ala-D-Ala carboxypeptidase family metallohydrolase
COORDINATES: similar to AA sequence:RefSeq:WP_011513814.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513813.1
COORDINATES: similar to AA sequence:RefSeq:WP_003658200.1
GO:0003924 - GTPase activity [Evidence IEA]; GO:0005047 - signal recognition particle binding [Evidence IEA]
signal recognition particle-docking protein FtsY
The repair of DNA containing O6-alkylated guanine is carried out by DNA-[protein]-cysteine S-methyltransferase.
COORDINATES: similar to AA sequence:RefSeq:WP_011513811.1
methylated-DNA--[protein]-cysteine S-methyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_076611531.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280214.1
YebC/PmpR family DNA-binding transcriptional regulator
COORDINATES: similar to AA sequence:RefSeq:WP_011513809.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443631.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513807.1
GO:0003855 - 3-dehydroquinate dehydratase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513806.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513805.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0003676 - nucleic acid binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513804.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443629.1
cbb3-type cytochrome oxidase assembly protein CcoS
COORDINATES: similar to AA sequence:RefSeq:WP_020443628.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513801.1
GO:0071949 - FAD binding [Evidence IEA]; GO:0008762 - UDP-N-acetylmuramate dehydrogenase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513800.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443626.1
COORDINATES: similar to AA sequence:RefSeq:WP_004695405.1
excalibur calcium-binding domain-containing protein
Serine metabolism, Threonine metabolism, Isoleucine biosynthesis
COORDINATES: similar to AA sequence:RefSeq:WP_005286113.1
GO:0004794 - L-threonine ammonia-lyase activity [Evidence IEA]
GO:0009097 - isoleucine biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020443624.1
helix-turn-helix transcriptional regulator
COORDINATES: similar to AA sequence:RefSeq:WP_009523256.1
GO:0008794 - arsenate reductase (glutaredoxin) activity [Evidence IEA]
This arsenate reductase requires both glutathione and glutaredoxin to convert arsenate to arsenite, after which the efflux transporter formed by ArsA and ArsB can extrude the arsenite from the cell, providing resistance; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_011513795.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513794.1
Ribose 5-phosphate isomerase, also known as phosphoriboisomerase, catalyses the conversion of D-ribose 5-phosphate to D-ribulose 5-phosphate in the non-oxidative branch of the pentose phosphate pathway.
COORDINATES: similar to AA sequence:RefSeq:WP_011513793.1
GO:0004751 - ribose-5-phosphate isomerase activity [Evidence IEA]
GO:0009052 - pentose-phosphate shunt, non-oxidative branch [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_003658302.1
GO:0004585 - ornithine carbamoyltransferase activity [Evidence IEA]
L- alanine to D- alanine for peptidoglycan synthesis
COORDINATES: similar to AA sequence:RefSeq:WP_011513791.1
GO:0008784 - alanine racemase activity [Evidence IEA]
The hexameric helicase DnaB unwinds the DNA duplex at the chromosome replication fork.
COORDINATES: similar to AA sequence:RefSeq:WP_010198448.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0003677 - DNA binding [Evidence IEA]; GO:0003678 - DNA helicase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020443618.1
GO:0050570 - 4-hydroxythreonine-4-phosphate dehydrogenase activity [Evidence IEA]
4-hydroxythreonine-4-phosphate dehydrogenase PdxA
COORDINATES: similar to AA sequence:RefSeq:WP_011280236.1
GO:0000179 - rRNA (adenine-N6,N6-)-dimethyltransferase activity [Evidence IEA]
16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA
Degradation of Diadenosine 5',5''-P1,P4-tetraphosphate (Ap4A), a regulatory metabolite of stress conditions
COORDINATES: similar to AA sequence:RefSeq:WP_011513786.1
GO:0008803 - bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity [Evidence IEA]
symmetrical bis(5'-nucleosyl)-tetraphosphatase
COORDINATES: similar to AA sequence:RefSeq:WP_011280238.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513784.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280240.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443609.1
16S rRNA (uracil(1498)-N(3))-methyltransferase
Methane metabolism, C1 Metabolism by Folate
COORDINATES: similar to AA sequence:RefSeq:WP_011960184.1
GO:0004489 - methylenetetrahydrofolate reductase (NAD(P)H) activity [Evidence IEA]
GO:0006555 - methionine metabolic process [Evidence IEA]
Selenoamino acid metabolism, Methionine metabolism
COORDINATES: similar to AA sequence:RefSeq:WP_020443608.1
GO:0004013 - adenosylhomocysteinase activity [Evidence IEA]
GO:0006730 - one-carbon metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513778.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513777.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443604.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443603.1
GO:0004425 - indole-3-glycerol-phosphate synthase activity [Evidence IEA]
GO:0006568 - tryptophan metabolic process [Evidence IEA]
indole-3-glycerol phosphate synthase TrpC
COORDINATES: similar to AA sequence:RefSeq:WP_011513773.1
GO:0004048 - anthranilate phosphoribosyltransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513772.1
aminodeoxychorismate/anthranilate synthase component II
Glutamine biosynthesis, Nitrogen metabolism, Peptidoglycan synthesis
COORDINATES: similar to AA sequence:RefSeq:WP_003657911.1
GO:0004356 - glutamate-ammonia ligase activity [Evidence IEA]
GO:0006542 - glutamine biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513770.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443599.1
The SIMPL domain is named for its presence in mouse protein SIMPL (signalling molecule that associates with mouse pelle-like kinase). Bacterial member BP26, from Brucella, was shown to assemble into a channel-like structure, while YggE from E. coli has been associated with resistance to oxidative stress; Derived by automated computational analysis using gene prediction method: Protein Homology.
signal recognition particle sRNA small type
COORDINATES: nucleotide motif:Rfam:14.4:RF00169
COORDINATES: similar to AA sequence:RefSeq:WP_001046679.1
COORDINATES: similar to AA sequence:RefSeq:WP_005097183.1
Predicted endonuclease, gp47 [Bacteriophage A118] related.
COORDINATES: similar to AA sequence:RefSeq:WP_011960593.1
COORDINATES: similar to AA sequence:RefSeq:WP_004831616.1
COORDINATES: protein motif:HMM:NF017885.2
COORDINATES: similar to AA sequence:RefSeq:WP_004831614.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280262.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280263.1
COORDINATES: similar to AA sequence:RefSeq:WP_010200468.1
COORDINATES: similar to AA sequence:RefSeq:WP_010197039.1
COORDINATES: similar to AA sequence:RefSeq:WP_007395091.1
COORDINATES: protein motif:HMM:NF016381.2
COORDINATES: similar to AA sequence:RefSeq:WP_002010005.1
COORDINATES: protein motif:HMM:NF024579.2
COORDINATES: protein motif:HMM:NF039367.1
COORDINATES: protein motif:HMM:NF039181.1
COORDINATES: similar to AA sequence:RefSeq:WP_004279610.1
COORDINATES: protein motif:HMM:NF016359.2
COORDINATES: protein motif:HMM:NF017850.2
from Interpro: This family of sequences are identified by a region of about 110 amino acids found exclusively in phage-related proteins, internally or toward the C terminus. One member, gp7 of phage SPP1, appears to be involved in head morphogenesis.
COORDINATES: protein motif:HMM:NF016148.2
from interpro: This family belongs to family U7 of the peptidase classification, and includes the potential protease SohB, a suppressor of the HTRA phenotype; and protease IV, an endopeptidase required to maintain proper secretion of mature proteins acros
COORDINATES: protein motif:HMM:NF013506.2
COORDINATES: similar to AA sequence:RefSeq:WP_005242557.1
COORDINATES: protein motif:HMM:NF015802.2
COORDINATES: protein motif:HMM:NF020688.2
COORDINATES: protein motif:HMM:NF018704.2
ATP/GTP-binding site motif A (P-loop): Phage virion morphogenesisThese sequences describe protein S of phage P2, suggested experimentally to act in tail completion and stable head joining, and related proteins from a number of phages.
COORDINATES: protein motif:HMM:NF016927.2
COORDINATES: protein motif:HMM:NF015807.2
COORDINATES: protein motif:HMM:NF016283.2
COORDINATES: protein motif:HMM:NF040129.1
COORDINATES: similar to AA sequence:RefSeq:WP_000999572.1
COORDINATES: protein motif:HMM:NF013152.2
COORDINATES: similar to AA sequence:RefSeq:WP_020443596.1
Serine biosynthesis, Vitamin-B6 metabolism
COORDINATES: similar to AA sequence:RefSeq:WP_010201924.1
GO:0003824 - catalytic activity [Evidence IEA]; GO:0004648 - O-phospho-L-serine:2-oxoglutarate aminotransferase activity [Evidence IEA]
GO:0006564 - L-serine biosynthetic process [Evidence IEA]
3-phosphoserine/phosphohydroxythreonine transaminase
COORDINATES: similar to AA sequence:RefSeq:WP_011280312.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443594.1
GO:0004416 - hydroxyacylglutathione hydrolase activity [Evidence IEA]
GO:0019243 - methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513762.1
microcin C ABC transporter permease YejB
COORDINATES: similar to AA sequence:RefSeq:WP_020443593.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513760.1
GO:0015833 - peptide transport [Evidence IEA]
dipeptide ABC transporter ATP-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_020443591.1
Peptide methionine sulphoxide reductase reverses the inactivation of many proteins due to the oxidation of critical methionine residues by reducing methionine sulphoxide, Met(O), to methionine.
COORDINATES: similar to AA sequence:RefSeq:WP_011513758.1
GO:0033744 - L-methionine:thioredoxin-disulfide S-oxidoreductase activity [Evidence IEA]; GO:0008113 - peptide-methionine (S)-S-oxide reductase activity [Evidence IEA]
peptide-methionine (S)-S-oxide reductase MsrA
COORDINATES: similar to AA sequence:RefSeq:WP_010196233.1
GO:0003934 - GTP cyclohydrolase I activity [Evidence IEA]
GO:0042559 - pteridine-containing compound biosynthetic process [Evidence IEA]; GO:0046654 - tetrahydrofolate biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513755.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443588.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513753.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443587.1
GO:0008509 - anion transmembrane transporter activity [Evidence IEA]
GO:0006820 - anion transport [Evidence IEA]
DASS family sodium-coupled anion symporter
COORDINATES: similar to AA sequence:RefSeq:WP_011513750.1
GO:0004386 - helicase activity [Evidence IEA]
GO:0006139 - nucleobase-containing compound metabolic process [Evidence IEA]
COORDINATES: protein motif:HMM:NF012432.2
COORDINATES: similar to AA sequence:RefSeq:WP_020443583.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513743.1
GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020443578.1
GO:0016149 - translation release factor activity, codon specific [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513740.1
GO:0004824 - lysine-tRNA ligase activity [Evidence IEA]
DNA polymerase III holoenzyme is responsible for the replication of the chromosome in bacteria. Both the gamma and tau subunits are 'motor' ATPases.
COORDINATES: similar to AA sequence:RefSeq:WP_020443574.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0003677 - DNA binding [Evidence IEA]; GO:0003887 - DNA-directed DNA polymerase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513737.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513736.1
aspartate aminotransferase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_011513735.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513734.1
COORDINATES: similar to AA sequence:RefSeq:WP_010198056.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443569.1
GO:0004637 - phosphoribosylamine-glycine ligase activity [Evidence IEA]
GO:0006189 - 'de novo' IMP biosynthetic process [Evidence IEA]; GO:0009152 - purine ribonucleotide biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513731.1
SbcCD is an ATP-dependent double-stranded DNA exonuclease. This complex functions in the initiation of recombination and recombinational repair and is particularly important in regulating the stability of DNA sections that can form secondary structures.
COORDINATES: similar to AA sequence:RefSeq:WP_011513730.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513729.1
exonuclease SbcCD subunit D C-terminal domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_020443566.1
GO:0051287 - NAD binding [Evidence IEA]; GO:0043115 - precorrin-2 dehydrogenase activity [Evidence IEA]; GO:0051266 - sirohydrochlorin ferrochelatase activity [Evidence IEA]; GO:0004851 - uroporphyrin-III C-methyltransferase activity [Evidence IEA]
GO:0019354 - siroheme biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513727.1
phosphoadenosine phosphosulfate reductase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_010198042.1
Selenoaminoacid metabolism and Sulfur fixation
COORDINATES: similar to AA sequence:RefSeq:WP_011513725.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513724.1
GO:0004781 - sulfate adenylyltransferase (ATP) activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020443560.1
GO:0015419 - ABC-type sulfate transporter activity [Evidence IEA]; GO:0043199 - sulfate binding [Evidence IEA]
GO:0008272 - sulfate transport [Evidence IEA]
sulfate ABC transporter substrate-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_011513721.1
COORDINATES: similar to AA sequence:RefSeq:WP_010198024.1
GO:0015419 - ABC-type sulfate transporter activity [Evidence IEA]
sulfate ABC transporter permease subunit CysT
COORDINATES: similar to AA sequence:RefSeq:WP_020443558.1
sulfate ABC transporter permease subunit CysW
COORDINATES: similar to AA sequence:RefSeq:WP_007393528.1
GO:0055052 - ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [Evidence IEA]; GO:0009898 - cytoplasmic side of plasma membrane [Evidence IEA]
GO:0015419 - ABC-type sulfate transporter activity [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA]
sulfate ABC transporter ATP-binding protein
trans-acting metalloregulatory protein for metal resistance in E.coli
COORDINATES: similar to AA sequence:RefSeq:WP_011513717.1
metalloregulator ArsR/SmtB family transcription factor
COORDINATES: similar to AA sequence:RefSeq:WP_010198018.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513715.1
GO:0008199 - ferric iron binding [Evidence IEA]; GO:0004322 - ferroxidase activity [Evidence IEA]
GO:0006880 - intracellular sequestering of iron ion [Evidence IEA]
Bacterioferritin (BFR; also known as cytochrome b1 or cytochrome b557) of Escherichia coli is an iron-storage protein consisting of 24 identical subunits that pack together to form a highly symmetrical, nearly spherical shell surrounding a central ca
COORDINATES: similar to AA sequence:RefSeq:WP_020443555.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443554.1
GO:0009410 - response to xenobiotic stimulus [Evidence IEA]; GO:0006855 - xenobiotic transmembrane transport [Evidence IEA]
DHA2 family efflux MFS transporter permease subunit
Bacterial GSTs of known function often have a specific, growth-supporting role in biodegradative metabolism: epoxide ring opening and tetrachlorohydroquinone reductive dehalogenation are two examples of the reactions catalysed by these bacterial GSTs. Som
COORDINATES: similar to AA sequence:RefSeq:WP_011513712.1
GO:0006749 - glutathione metabolic process [Evidence IEA]
glutathione-dependent disulfide-bond oxidoreductase
COORDINATES: similar to AA sequence:RefSeq:WP_020443553.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443552.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280357.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443550.1
PLP-dependent aminotransferase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_020443549.1
COORDINATES: protein motif:HMM:NF014585.2
hydantoinase B/oxoprolinase family protein
COORDINATES: protein motif:HMM:NF024706.2
COORDINATES: protein motif:HMM:NF014691.2
COORDINATES: similar to AA sequence:RefSeq:WP_011513703.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443544.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280364.1
COORDINATES: similar to AA sequence:RefSeq:WP_004696094.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443524.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513658.1
COORDINATES: similar to AA sequence:RefSeq:WP_011960001.1
COORDINATES: similar to AA sequence:RefSeq:WP_010200977.1
acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
COORDINATES: similar to AA sequence:RefSeq:WP_010200976.1
Involved in the utilization of lactams such as 2-pyrrolidinone
COORDINATES: similar to AA sequence:RefSeq:WP_010200975.1
possibly functions with subunit1 converts urea-1-carboxylate and water to 2 carbon dioxide and 2 ammonia
COORDINATES: similar to AA sequence:RefSeq:WP_011280372.1
biotin-dependent carboxyltransferase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_011280373.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280374.1
GO:0003989 - acetyl-CoA carboxylase activity [Evidence IEA]; GO:0004075 - biotin carboxylase activity [Evidence IEA]
acetyl-CoA carboxylase biotin carboxylase subunit
COORDINATES: similar to AA sequence:RefSeq:WP_010200967.1
acetyl-CoA carboxylase biotin carboxyl carrier protein
COORDINATES: similar to AA sequence:RefSeq:WP_011280376.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513649.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443513.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513647.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513646.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513645.1
COORDINATES: similar to AA sequence:RefSeq:WP_004830929.1
GO:0046421 - methylisocitrate lyase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011280384.1
GO:0050440 - 2-methylcitrate synthase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513642.1
GO:0047456 - 2-methylisocitrate dehydratase activity [Evidence IEA]
Fe/S-dependent 2-methylisocitrate dehydratase AcnD
COORDINATES: similar to AA sequence:RefSeq:WP_010200428.1
type II toxin-antitoxin system RelE/ParE family toxin
COORDINATES: similar to AA sequence:RefSeq:WP_007113097.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443505.1
2-methylaconitate cis-trans isomerase PrpF
COORDINATES: similar to AA sequence:RefSeq:WP_011513636.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443502.1
GO:0051537 - 2 iron, 2 sulfur cluster binding [Evidence IEA]; GO:0047547 - 2-methylcitrate dehydratase activity [Evidence IEA]
GO:0019679 - propionate metabolic process, methylcitrate cycle [Evidence IEA]
bifunctional 2-methylcitrate dehydratase/aconitate hydratase
COORDINATES: similar to AA sequence:RefSeq:WP_020443501.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513632.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443499.1
provides power for ArsB to pump out arsenite and antimonite
COORDINATES: similar to AA sequence:RefSeq:WP_020443498.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513629.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513628.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443496.1
Purine metabolism: May act on all substrates above to produce nucleoside 5'-monophosphates.
COORDINATES: similar to AA sequence:RefSeq:WP_011513626.1
GO:0009116 - nucleoside metabolic process [Evidence IEA]
hypoxanthine-guanine phosphoribosyltransferase
Exoribodeoxynuclease V unwinds and degrades double stranded DNA prior to recombination. When chi sites are encountered, the alpha subunit (recD) is released and degradation stops while unwinding continues.
COORDINATES: similar to AA sequence:RefSeq:WP_020443495.1
GO:0009338 - exodeoxyribonuclease V complex [Evidence IEA]
GO:0008854 - exodeoxyribonuclease V activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513624.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443493.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443492.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443491.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513605.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443478.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513607.1
class III extradiol ring-cleavage dioxygenase
COORDINATES: similar to AA sequence:RefSeq:WP_020443490.1
frameshifted; internal stop; incomplete; partial in the middle of a contig; missing N-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: protein motif:HMM:NF024949.2
COORDINATES: protein motif:HMM:NF019421.2
type II toxin-antitoxin system HipA family toxin
COORDINATES: similar to AA sequence:RefSeq:WP_020443964.1
GO:0008964 - phosphoenolpyruvate carboxylase activity [Evidence IEA]
GO:0015977 - carbon fixation [Evidence IEA]; GO:0006099 - tricarboxylic acid cycle [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020444448.1
GO:0016740 - transferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020444449.1
GO:0046917 - triphosphoribosyl-dephospho-CoA synthase activity [Evidence IEA]
GO:0019361 - 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthetic process [Evidence IEA]
triphosphoribosyl-dephospho-CoA synthase MdcB
COORDINATES: similar to AA sequence:RefSeq:WP_020444450.1
GO:0051191 - prosthetic group biosynthetic process [Evidence IEA]
malonate decarboxylase holo-[acyl-carrier-protein] synthase
COORDINATES: similar to AA sequence:RefSeq:WP_004981496.1
GO:0044262 - cellular carbohydrate metabolic process [Evidence IEA]
biotin-independent malonate decarboxylase subunit gamma
COORDINATES: similar to AA sequence:RefSeq:WP_004981499.1
GO:0003989 - acetyl-CoA carboxylase activity [Evidence IEA]; GO:0016831 - carboxy-lyase activity [Evidence IEA]
GO:0044262 - cellular carbohydrate metabolic process [Evidence IEA]; GO:0006633 - fatty acid biosynthetic process [Evidence IEA]
biotin-independent malonate decarboxylase subunit beta
COORDINATES: similar to AA sequence:RefSeq:WP_020444453.1
malonate decarboxylase acyl carrier protein
COORDINATES: similar to AA sequence:RefSeq:WP_020444454.1
GO:0015451 - decarboxylation-driven active transmembrane transporter activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011280420.1
GO:0005342 - organic acid transmembrane transporter activity [Evidence IEA]
GO:0015849 - organic acid transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020444456.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444457.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514103.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280424.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514101.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514100.1
COORDINATES: protein motif:HMM:NF018628.2
COORDINATES: similar to AA sequence:RefSeq:WP_011513559.1
Degradation of purine-nucleosides to purine and alpha-D-ribose 1-phosphate.
COORDINATES: similar to AA sequence:RefSeq:WP_020443457.1
GO:0017061 - S-methyl-5-thioadenosine phosphorylase activity [Evidence IEA]
GO:0006168 - adenine salvage [Evidence IEA]; GO:0019509 - L-methionine salvage from methylthioadenosine [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020443456.1
methyltransferase domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_020443455.1
TIGR04282 family arsenosugar biosynthesis glycosyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_020443454.1
TIGR04283 family arsenosugar biosynthesis glycosyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_020443453.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280433.1
Some members of this family are selenoproteins; Derived by automated computational analysis using gene prediction method: Protein Homology.
arsenosugar biosynthesis radical SAM protein ArsS
COORDINATES: similar to AA sequence:RefSeq:WP_011513578.1
GO:0016772 - transferase activity, transferring phosphorus-containing groups [Evidence IEA]
phosphoethanolamine--lipid A transferase
COORDINATES: similar to AA sequence:RefSeq:WP_011513577.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513576.1
HAMP domain-containing sensor histidine kinase
dgkA is an enzyme that catalyzes the formation of phosphatidic acid from diacylglycerol and ATP, an important step in phospholipid biosynthesis.
COORDINATES: similar to AA sequence:RefSeq:WP_020443439.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443438.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443436.1
COORDINATES: similar to AA sequence:RefSeq:WP_010199738.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513570.1
COORDINATES: similar to AA sequence:RefSeq:WP_001206197.1
GO:0016746 - acyltransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_017816179.1
COORDINATES: similar to AA sequence:RefSeq:WP_010199723.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443430.1
uptake of short/medium chain saturated dicarboxylates
COORDINATES: similar to AA sequence:RefSeq:WP_020443429.1
COORDINATES: similar to AA sequence:RefSeq:WP_076611658.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280447.1
COORDINATES: similar to AA sequence:RefSeq:WP_019520517.1
acetyl-CoA hydrolase/transferase family protein
Glutathione metabolism: Tranfers gamma-glutamate residue from glutathione to L-amino acids. Detoxification of drugs and xenobiotics
COORDINATES: similar to AA sequence:RefSeq:WP_011280449.1
The DNA polymerase III holoenzyme is responsible for the replication of the chromosome.
COORDINATES: similar to AA sequence:RefSeq:WP_007393434.1
GO:0008408 - 3'-5' exonuclease activity [Evidence IEA]; GO:0003676 - nucleic acid binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020443410.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513544.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443408.1
GO:0009001 - serine O-acetyltransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513542.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513541.1
GO:0004150 - dihydroneopterin aldolase activity [Evidence IEA]
GO:0006760 - folic acid-containing compound metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513540.1
GO:0005215 - transporter activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_003658253.1
GO:0008977 - prephenate dehydrogenase (NAD+) activity [Evidence IEA]
GO:0009073 - aromatic amino acid family biosynthetic process [Evidence IEA]
bifunctional prephenate dehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase
Phenylalanine metabolism and biosynthesis, histidine metabolism, tyrosine metabolism.
COORDINATES: similar to AA sequence:RefSeq:WP_011280458.1
GO:0004400 - histidinol-phosphate transaminase activity [Evidence IEA]
GO:0000105 - histidine biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011280459.1
GO:0004664 - prephenate dehydratase activity [Evidence IEA]
GO:0009094 - L-phenylalanine biosynthetic process [Evidence IEA]
catalyzes the reversible transfer of a three-carbon ketol unit from sedoheptulose 7-phosphate to glyceraldehyde 3-phosphate to form erythrose 4-phosphate and fructose 6-phosphate together with transketolase link the glycolytic and pentose-phosphate pathwa
COORDINATES: similar to AA sequence:RefSeq:WP_020443403.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280461.1
Purine metabolism: Biosynthesis of AMP from Adenine, Biosynthesis of 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide from 5-amino-4-imidazolecarboxyamide
COORDINATES: similar to AA sequence:RefSeq:WP_020443401.1
GO:0003999 - adenine phosphoribosyltransferase activity [Evidence IEA]
Rubredoxin is a low molecular weight iron-containing bacterial protein involved in electron transfer sometimes replacing ferredoxin as an electron carrier
COORDINATES: similar to AA sequence:RefSeq:WP_004990351.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280464.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513532.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280466.1
COORDINATES: protein motif:HMM:TIGR01414.1
autotransporter domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_011513530.1
GO:0015205 - nucleobase transmembrane transporter activity [Evidence IEA]
GO:0015851 - nucleobase transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020443397.1
GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; GO:0003941 - L-serine ammonia-lyase activity [Evidence IEA]
GO:0009063 - amino acid catabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020443396.1
COORDINATES: similar to AA sequence:RefSeq:WP_017387487.1
GO:0004358 - glutamate N-acetyltransferase activity [Evidence IEA]
GO:0006526 - arginine biosynthetic process [Evidence IEA]
bifunctional glutamate N-acetyltransferase/amino-acid acetyltransferase ArgJ
All proteins in this family for which functions are known are 5' AP endonucleases that function in base excision repair and the repair of abasic sites in DNA.
COORDINATES: similar to AA sequence:RefSeq:WP_011513526.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0004519 - endonuclease activity [Evidence IEA]; GO:0008853 - exodeoxyribonuclease III activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010202012.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280474.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513518.1
GO:0008233 - peptidase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020443385.1
GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA]; GO:0016874 - ligase activity [Evidence IEA]; GO:0000166 - nucleotide binding [Evidence IEA]
GO:0006418 - tRNA aminoacylation for protein translation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020443384.1
COORDINATES: similar to AA sequence:RefSeq:WP_011960259.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443380.1
COORDINATES: similar to AA sequence:RefSeq:WP_011960256.1
COORDINATES: similar to AA sequence:RefSeq:WP_005109448.1
GO:0008460 - dTDP-glucose 4,6-dehydratase activity [Evidence IEA]
GO:0019305 - dTDP-rhamnose biosynthetic process [Evidence IEA]; GO:0009243 - O antigen biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004749723.1
COORDINATES: similar to AA sequence:RefSeq:WP_000084516.1
GO:0008879 - glucose-1-phosphate thymidylyltransferase activity [Evidence IEA]
glucose-1-phosphate thymidylyltransferase RfbA
COORDINATES: similar to AA sequence:RefSeq:WP_004749719.1
GO:0008830 - dTDP-4-dehydrorhamnose 3,5-epimerase activity [Evidence IEA]
Leucine biosynthesis and degradation. CoA biosynthesis.
COORDINATES: similar to AA sequence:RefSeq:WP_011513510.1
GO:0004084 - branched-chain-amino-acid transaminase activity [Evidence IEA]
GO:0009081 - branched-chain amino acid metabolic process [Evidence IEA]
Regulates glutamate-ammonia ligase by adenylation in response to cellular nitrogen status.
COORDINATES: similar to AA sequence:RefSeq:WP_020443376.1
GO:0008882 - [glutamate-ammonia-ligase] adenylyltransferase activity [Evidence IEA]
bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_011513508.1
GO:0016783 - sulfurtransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020443374.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513506.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513505.1
TusE/DsrC/DsvC family sulfur relay protein
COORDINATES: similar to AA sequence:RefSeq:WP_011513504.1
tRNA (cytidine(34)-2'-O)-methyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_004705782.1
GO:0009636 - response to toxic substance [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513503.1
GO:0051989 - coproporphyrinogen dehydrogenase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010201262.1
GO:0042910 - xenobiotic transmembrane transporter activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004915532.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280499.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513498.1
COORDINATES: similar to AA sequence:RefSeq:WP_010201254.1
GO:0003852 - 2-isopropylmalate synthase activity [Evidence IEA]
GO:0009098 - leucine biosynthetic process [Evidence IEA]
helix turn helix motif suggestd transcriptional regulation
COORDINATES: similar to AA sequence:RefSeq:WP_011280502.1
Lrp/AsnC family transcriptional regulator
COORDINATES: similar to AA sequence:RefSeq:WP_011513495.1
protein kinase activity (amino acid phosphorylation)
COORDINATES: similar to AA sequence:RefSeq:WP_020443362.1
COORDINATES: similar to AA sequence:RefSeq:WP_007393936.1
Possibly involved in ubiquinone synthesis
COORDINATES: similar to AA sequence:RefSeq:WP_011513492.1
GO:0018364 - peptidyl-glutamine methylation [Evidence IEA]; GO:0006412 - translation [Evidence IEA]
peptide chain release factor N(5)-glutamine methyltransferase
Probably acts as a uuptake transporter and signal transducer in the beta-lactamase induction system and in peptidoglycan recycling.
COORDINATES: similar to AA sequence:RefSeq:WP_020443359.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443358.1
LysR substrate-binding domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_007395427.1
GO:0016020 - membrane [Evidence IEA]; GO:0030288 - outer membrane-bounded periplasmic space [Evidence IEA]
GO:0016491 - oxidoreductase activity [Evidence IEA]; GO:0048038 - quinone binding [Evidence IEA]
membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family
COORDINATES: similar to AA sequence:RefSeq:WP_010201234.1
LLM class flavin-dependent oxidoreductase
COORDINATES: similar to AA sequence:RefSeq:WP_020443355.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443354.1
GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]
GO:0008033 - tRNA processing [Evidence IEA]; GO:0002098 - tRNA wobble uridine modification [Evidence IEA]
tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG
COORDINATES: similar to AA sequence:RefSeq:WP_020443353.1
COORDINATES: similar to AA sequence:RefSeq:WP_010201219.1
GO:0009055 - electron transfer activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020443352.1
GO:0008685 - 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity [Evidence IEA]
GO:0019288 - isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [Evidence IEA]
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
COORDINATES: similar to AA sequence:RefSeq:WP_010201209.1
GO:0016783 - sulfurtransferase activity [Evidence IEA]; GO:0016740 - transferase activity [Evidence IEA]
'de novo' Purine biosynthesis: Biosynthesis of Inosine monophosphate, Biosynthesis of Adenosine monophosphate
COORDINATES: similar to AA sequence:RefSeq:YP_004996178.1
GO:0004018 - N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity [Evidence IEA]
GO:0006188 - IMP biosynthetic process [Evidence IEA]; GO:0009152 - purine ribonucleotide biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_005176688.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513480.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280520.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443342.1
GO:0003842 - 1-pyrroline-5-carboxylate dehydrogenase activity [Evidence IEA]; GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]; GO:0004657 - proline dehydrogenase activity [Evidence IEA]
GO:0010133 - proline catabolic process to glutamate [Evidence IEA]; GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]
bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase PutA
COORDINATES: similar to AA sequence:RefSeq:WP_020443339.1
GO:0015078 - proton transmembrane transporter activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513471.1
GO:0098567 - periplasmic side of plasma membrane [Evidence IEA]
GO:0061024 - membrane organization [Evidence IEA]; GO:1902600 - proton transmembrane transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513470.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280525.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513671.1
COORDINATES: similar to AA sequence:RefSeq:WP_010201162.1
integral membrane proteins of unknown function
COORDINATES: protein motif:HMM:NF016064.2
COORDINATES: similar to AA sequence:RefSeq:WP_010201158.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513463.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443329.1
outer membrane protein assembly factor BamD
DNA primase is a nucleotidyltransferase that synthesises the oligoribonucleotide primers required for DNA replication on the lagging strand of the replication fork; it can also prime the leading stand.
COORDINATES: similar to AA sequence:RefSeq:WP_011513461.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0003896 - DNA primase activity [Evidence IEA]; GO:0008270 - zinc ion binding [Evidence IEA]
CHC2 zinc finger domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_010201151.1
GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; GO:0016987 - sigma factor activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010199112.1
COORDINATES: similar to AA sequence:RefSeq:WP_010198754.1
Interconversion of Ribonucleotides and Deoxyribonucleotides
COORDINATES: similar to AA sequence:RefSeq:WP_003669739.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0004748 - ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor [Evidence IEA]
ribonucleoside-diphosphate reductase subunit alpha
COORDINATES: similar to AA sequence:RefSeq:WP_005124630.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443322.1
type II toxin-antitoxin system Phd/YefM family antitoxin
COORDINATES: similar to AA sequence:RefSeq:WP_020443321.1
type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family
COORDINATES: similar to AA sequence:RefSeq:WP_020443320.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513454.1
GO:0009263 - deoxyribonucleotide biosynthetic process [Evidence IEA]
ribonucleotide-diphosphate reductase subunit beta
COORDINATES: similar to AA sequence:RefSeq:WP_011513453.1
GO:0051537 - 2 iron, 2 sulfur cluster binding [Evidence IEA]
class I ribonucleotide reductase maintenance protein YfaE
COORDINATES: similar to AA sequence:RefSeq:WP_011513452.1
trypsin-like peptidase domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_011513451.1
GO:0051540 - metal cluster binding [Evidence IEA]
Nif3-like dinuclear metal center hexameric protein
COORDINATES: similar to AA sequence:RefSeq:WP_011513450.1
transglycosylase SLT domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_011513449.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513448.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443314.1
COORDINATES: similar to AA sequence:RefSeq:WP_000051669.1
COORDINATES: similar to AA sequence:RefSeq:WP_003658056.1
GO:0031522 - cell envelope Sec protein transport complex [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020443312.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513443.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513442.1
Possible branched chain amino acid efflux pump, LivE family, small subunit
COORDINATES: similar to AA sequence:RefSeq:WP_011513441.1
Purine biosynthesis, Glutamate metabolism: Glutamine is amine donor
COORDINATES: similar to AA sequence:RefSeq:WP_003671055.1
GO:0004044 - amidophosphoribosyltransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010198340.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280556.1
GO:0004152 - dihydroorotate dehydrogenase activity [Evidence IEA]
GO:0006222 - UMP biosynthetic process [Evidence IEA]
quinone-dependent dihydroorotate dehydrogenase
COORDINATES: similar to AA sequence:RefSeq:WP_011280557.1
GO:0101006 - protein histidine phosphatase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020443301.1
NAD(P)H-dependent glycerol-3-phosphate dehydrogenase
COORDINATES: similar to AA sequence:RefSeq:WP_020443300.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443299.1
GO:0051301 - cell division [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020443298.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513429.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513428.1
GO:0009318 - exodeoxyribonuclease VII complex [Evidence IEA]
GO:0008855 - exodeoxyribonuclease VII activity [Evidence IEA]
GO:0006308 - DNA catabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010198302.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443295.1
GO:0004516 - nicotinate phosphoribosyltransferase activity [Evidence IEA]
GO:0019358 - nicotinate nucleotide salvage [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513422.1
Adds lipoate to enzymes requiring lipoic acid in the active site.
COORDINATES: similar to AA sequence:RefSeq:WP_011513421.1
COORDINATES: similar to AA sequence:RefSeq:WP_010198287.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513419.1
COORDINATES: similar to AA sequence:RefSeq:WP_004707905.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443284.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513415.1
GO:0003824 - catalytic activity [Evidence IEA]; GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; GO:0016491 - oxidoreductase activity [Evidence IEA]; GO:0017150 - tRNA dihydrouridine synthase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020443282.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443281.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443280.1
Dihydroxy-acid dehydratase catalyzes the fourth step in the biosynthesis of isoleucine and valine, the dehydratation of 2,3-dihydroxy-isovaleic acid into alpha-ketoisovaleric acid. 6-
COORDINATES: similar to AA sequence:RefSeq:WP_011280576.1
GO:0004160 - dihydroxy-acid dehydratase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010198223.1
catalyses the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics
COORDINATES: similar to AA sequence:RefSeq:WP_011513409.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513408.1
sulfur transferase domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_020443276.1
MaoC/PaaZ C-terminal domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_005240885.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443274.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513404.1
GO:0005575 - cellular_component [Evidence IEA]
GO:0008976 - polyphosphate kinase activity [Evidence IEA]
GO:0006793 - phosphorus metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011280584.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513402.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280586.1
GO:0008690 - 3-deoxy-manno-octulosonate cytidylyltransferase activity [Evidence IEA]
GO:0009244 - lipopolysaccharide core region biosynthetic process [Evidence IEA]
3-deoxy-manno-octulosonate cytidylyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_011280587.1
GO:0009029 - tetraacyldisaccharide 4'-kinase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020443269.1
GO:0005319 - lipid transporter activity [Evidence IEA]
GO:0006869 - lipid transport [Evidence IEA]
lipid A export permease/ATP-binding protein MsbA
COORDINATES: similar to AA sequence:RefSeq:WP_020443268.1
COORDINATES: similar to AA sequence:RefSeq:WP_010198190.1
MotA/TolQ/ExbB proton channel family protein
COORDINATES: similar to AA sequence:RefSeq:WP_011513396.1
GO:0007059 - chromosome segregation [Evidence IEA]; GO:0000910 - cytokinesis [Evidence IEA]
ParB/RepB/Spo0J family partition protein
COORDINATES: similar to AA sequence:RefSeq:WP_011280592.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443264.1
GO:0046118 - 7-methylguanosine biosynthetic process [Evidence IEA]; GO:0031167 - rRNA methylation [Evidence IEA]
16S rRNA (guanine(527)-N(7))-methyltransferase RsmG
COORDINATES: similar to AA sequence:RefSeq:WP_020443263.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443262.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513391.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443260.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443259.1
COORDINATES: similar to AA sequence:RefSeq:WP_003658244.1
COORDINATES: similar to AA sequence:RefSeq:WP_010198169.1
GO:0045250 - cytosolic pyruvate dehydrogenase complex [Evidence IEA]
GO:0004738 - pyruvate dehydrogenase activity [Evidence IEA]
GO:0006086 - acetyl-CoA biosynthetic process from pyruvate [Evidence IEA]
pyruvate dehydrogenase (acetyl-transferring), homodimeric type
COORDINATES: similar to AA sequence:RefSeq:WP_011513381.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280602.1
COORDINATES: similar to AA sequence:RefSeq:WP_004809525.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443249.1
GO:0004370 - glycerol kinase activity [Evidence IEA]
GO:0006071 - glycerol metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010198792.1
GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; GO:0003957 - NAD(P)+ transhydrogenase (B-specific) activity [Evidence IEA]
GO:0045454 - cell redox homeostasis [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_041753451.1
pyruvate, water dikinase activity in gluconeogenesis
COORDINATES: similar to AA sequence:RefSeq:WP_011280607.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0008986 - pyruvate, water dikinase activity [Evidence IEA]; GO:0016772 - transferase activity, transferring phosphorus-containing groups [Evidence IEA]
GO:0016310 - phosphorylation [Evidence IEA]; GO:0006090 - pyruvate metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513371.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513370.1
COORDINATES: similar to AA sequence:RefSeq:WP_010198808.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280610.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513368.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443240.1
COORDINATES: similar to AA sequence:RefSeq:WP_000343613.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513358.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443234.1
COORDINATES: protein motif:HMM:NF012789.2
COORDINATES: similar to AA sequence:RefSeq:WP_010201087.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513355.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280619.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513353.1
COORDINATES: similar to AA sequence:RefSeq:WP_010201081.1
GO:0046872 - metal ion binding [Evidence IEA]; GO:0016491 - oxidoreductase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007393571.1
type 1 glutamine amidotransferase domain-containing protein
COORDINATES: protein motif:HMM:NF024809.2
COORDINATES: similar to AA sequence:RefSeq:WP_020443227.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513347.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443225.1
GO:0010181 - FMN binding [Evidence IEA]; GO:0004733 - pyridoxamine-phosphate oxidase activity [Evidence IEA]
intramolecular transferase activity, phosphotransferases
COORDINATES: similar to AA sequence:RefSeq:WP_020443224.1
GO:0016868 - intramolecular transferase activity, phosphotransferases [Evidence IEA]; GO:0000287 - magnesium ion binding [Evidence IEA]; GO:0008966 - phosphoglucosamine mutase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_003659156.1
GO:0003938 - IMP dehydrogenase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011280630.1
GO:0004817 - cysteine-tRNA ligase activity [Evidence IEA]
GO:0006423 - cysteinyl-tRNA aminoacylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020443221.1
GO:0008817 - corrinoid adenosyltransferase activity [Evidence IEA]
GO:0009236 - cobalamin biosynthetic process [Evidence IEA]
cob(I)yrinic acid a,c-diamide adenosyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_020443220.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443219.1
COORDINATES: similar to AA sequence:RefSeq:WP_011960519.1
GO:0006629 - lipid metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_019383728.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443216.1
adds the CCA to the 3' of the tRNA EC: 2.7.7.25.
COORDINATES: similar to AA sequence:RefSeq:WP_020443215.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513335.1
COORDINATES: similar to AA sequence:RefSeq:WP_011960524.1
COORDINATES: protein motif:HMM:TIGR02256.1
COORDINATES: similar to AA sequence:RefSeq:WP_002058106.1
GO:0008641 - ubiquitin-like modifier activating enzyme activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_005161563.1
COORDINATES: similar to AA sequence:RefSeq:WP_004804415.1
COORDINATES: protein motif:HMM:NF015210.2
COORDINATES: similar to AA sequence:RefSeq:WP_003409385.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513287.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513286.1
protein phosphatase 2C domain-containing protein
COORDINATES: protein motif:HMM:NF023550.2
COORDINATES: similar to AA sequence:RefSeq:WP_020443203.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513322.1
Threonine biosynthesis and metabolism, Serine biosynthesis and metabolism
COORDINATES: similar to AA sequence:RefSeq:WP_020443202.1
Cleaves 3-hydroxyaspartate into glyoxylate and glycine
COORDINATES: similar to AA sequence:RefSeq:WP_011513320.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513319.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280661.1
bifunctional TVP38/TMEM64 family protein/FAD-dependent oxidoreductase
COORDINATES: similar to AA sequence:RefSeq:WP_020443194.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513312.1
Many of these proteins function as repressors that control the level of susceptibility to hydrophobic antibiotics and detergents.
COORDINATES: similar to AA sequence:RefSeq:WP_011513310.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513309.1
GO:0018784 - (S)-2-haloacid dehalogenase activity [Evidence IEA]
GO:0006805 - xenobiotic metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004702033.1
COORDINATES: similar to AA sequence:RefSeq:WP_019457521.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280668.1
GO:0070403 - NAD+ binding [Evidence IEA]
GO:0006631 - fatty acid metabolic process [Evidence IEA]
3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_010198598.1
COORDINATES: protein motif:HMM:NF019301.2
COORDINATES: similar to AA sequence:RefSeq:WP_011513874.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513875.1
Phenylalanine biosynthesis and metabolism, Tyrosine biosynthesis and metabolism
COORDINATES: similar to AA sequence:RefSeq:WP_011513886.1
aspartate/tyrosine/aromatic aminotransferase
COORDINATES: similar to AA sequence:RefSeq:WP_020443708.1
GO:0016853 - isomerase activity [Evidence IEA]; GO:0016740 - transferase activity [Evidence IEA]
tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA
contains LYsM domain may have a general peptidoglycan binding function.
COORDINATES: similar to AA sequence:RefSeq:WP_011513894.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513895.1
Asparagine metabolism to aspartate, Nitrogen metabolism
COORDINATES: similar to AA sequence:RefSeq:WP_011513896.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280677.1
COORDINATES: similar to AA sequence:RefSeq:WP_010199824.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443714.1
GO:0003862 - 3-isopropylmalate dehydrogenase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020443715.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443716.1
GO:0009316 - 3-isopropylmalate dehydratase complex [Evidence IEA]
GO:0003861 - 3-isopropylmalate dehydratase activity [Evidence IEA]
3-isopropylmalate dehydratase small subunit
COORDINATES: similar to AA sequence:RefSeq:WP_011280682.1
3-isopropylmalate dehydratase large subunit
COORDINATES: similar to AA sequence:RefSeq:WP_013107970.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280684.1
GO:0005298 - proline:sodium symporter activity [Evidence IEA]
GO:0015824 - proline transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513905.1
outer membrane protein transport protein
possibly involved in long chain fatty acid uptake (FadL - E. coli) or toluene and other organic compounds
COORDINATES: similar to AA sequence:RefSeq:WP_011513906.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280687.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443721.1
COORDINATES: similar to AA sequence:RefSeq:WP_003657575.1
GO:0045275 - respiratory chain complex III [Evidence IEA]
GO:0009055 - electron transfer activity [Evidence IEA]; GO:0008121 - ubiquinol-cytochrome-c reductase activity [Evidence IEA]
GO:0009060 - aerobic respiration [Evidence IEA]
ubiquinol-cytochrome c reductase iron-sulfur subunit
COORDINATES: similar to AA sequence:RefSeq:WP_003657576.1
cytochrome bc complex cytochrome b subunit
COORDINATES: similar to AA sequence:RefSeq:WP_011513911.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443723.1
glutathione S-transferase N-terminal domain-containing protein
binds to ssrA tagged proteins and enchances ClpX degradation of incomplete protein products.
COORDINATES: similar to AA sequence:RefSeq:WP_020443724.1
ClpXP protease specificity-enhancing factor
COORDINATES: similar to AA sequence:RefSeq:WP_000985727.1
GO:0008829 - dCTP deaminase activity [Evidence IEA]
GO:0009394 - 2'-deoxyribonucleotide metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020443727.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0016887 - ATP hydrolysis activity [Evidence IEA]; GO:0051536 - iron-sulfur cluster binding [Evidence IEA]
iron-sulfur cluster carrier protein ApbC
COORDINATES: similar to AA sequence:RefSeq:WP_011280696.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513919.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513920.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443731.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443732.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0004825 - methionine-tRNA ligase activity [Evidence IEA]; GO:0000166 - nucleotide binding [Evidence IEA]
GO:0006431 - methionyl-tRNA aminoacylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513923.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443733.1
ABC transporter substrate-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_010199930.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280704.1
COORDINATES: similar to AA sequence:RefSeq:WP_010199934.1
likely to belong to two-component sensory transduction system where the protein is activated by its phosphorylation, generally on an aspartate residue, by a transmembrane kinase. The proteins that belong to this class include bvgA, comA, dctR; degU, evgA
COORDINATES: protein motif:HMM:NF012301.2
COORDINATES: protein motif:HMM:NF024376.2
PhnD/SsuA/transferrin family substrate-binding protein
COORDINATES: protein motif:HMM:NF012264.2
COORDINATES: protein motif:HMM:NF024834.2
COORDINATES: similar to AA sequence:RefSeq:WP_010199937.1
COORDINATES: similar to AA sequence:RefSeq:WP_010199939.1
GO:0009326 - formate dehydrogenase complex [Evidence IEA]
GO:0008863 - formate dehydrogenase (NAD+) activity [Evidence IEA]
GO:0009061 - anaerobic respiration [Evidence IEA]; GO:0015942 - formate metabolic process [Evidence IEA]
formate dehydrogenase accessory sulfurtransferase FdhD
COORDINATES: similar to AA sequence:RefSeq:WP_011959554.1
COORDINATES: protein motif:HMM:NF038354.1
COORDINATES: protein motif:HMM:NF037660.2
LuxR C-terminal-related transcriptional regulator
COORDINATES: protein motif:HMM:NF014071.2
hydantoinase/oxoprolinase family protein
COORDINATES: protein motif:HMM:NF020456.2
COORDINATES: nucleotide motif:Rfam:14.4:RF00023
COORDINATES: similar to AA sequence:RefSeq:WP_013107814.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513961.1
GO:0004107 - chorismate synthase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011280722.1
GO:0008276 - protein methyltransferase activity [Evidence IEA]; GO:0008757 - S-adenosylmethionine-dependent methyltransferase activity [Evidence IEA]
GO:0018364 - peptidyl-glutamine methylation [Evidence IEA]; GO:0042273 - ribosomal large subunit biogenesis [Evidence IEA]
50S ribosomal protein L3 N(5)-glutamine methyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_011513963.1
COORDINATES: similar to AA sequence:RefSeq:WP_003660657.1
Catalyse the attachment of an amino acid to its cognate transfer RNA molecule
COORDINATES: similar to AA sequence:RefSeq:WP_010199429.1
GO:0004813 - alanine-tRNA ligase activity [Evidence IEA]
GO:0006419 - alanyl-tRNA aminoacylation [Evidence IEA]
Biosynthesis of Lysine, Diaminopimellate, Methionine and Threonine from Aspartate
COORDINATES: similar to AA sequence:RefSeq:WP_010199426.1
GO:0004072 - aspartate kinase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_002209449.1
GO:0006402 - mRNA catabolic process [Evidence IEA]; GO:0006109 - regulation of carbohydrate metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011513967.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280730.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443747.1
GO:0003951 - NAD+ kinase activity [Evidence IEA]
GO:0006741 - NADP biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011280732.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443749.1
responsible for the final stages of peptidoglycan biosynthesis for cell wall formation
COORDINATES: similar to AA sequence:RefSeq:WP_011513972.1
GO:0009274 - peptidoglycan-based cell wall [Evidence IEA]
GO:0008658 - penicillin binding [Evidence IEA]; GO:0008233 - peptidase activity [Evidence IEA]; GO:0008955 - peptidoglycan glycosyltransferase activity [Evidence IEA]
GO:0009252 - peptidoglycan biosynthetic process [Evidence IEA]; GO:0046677 - response to antibiotic [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020443751.1
Ribosomal protein L11 methyltransferase is an S-adenosyl-L-methionine-dependent methyltransferase required for the modification of ribosomal protein L11
COORDINATES: similar to AA sequence:RefSeq:WP_010199392.1
50S ribosomal protein L11 methyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_011960844.1
DNA-binding transcriptional regulator Fis
'de novo' synthesis of Purines: Biosynthesis of Inosine monophosphate
COORDINATES: similar to AA sequence:RefSeq:WP_003659336.1
GO:0003824 - catalytic activity [Evidence IEA]; GO:0003937 - IMP cyclohydrolase activity [Evidence IEA]; GO:0004643 - phosphoribosylaminoimidazolecarboxamide formyltransferase activity [Evidence IEA]
GO:0006189 - 'de novo' IMP biosynthetic process [Evidence IEA]; GO:0006164 - purine nucleotide biosynthetic process [Evidence IEA]
bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
COORDINATES: similar to AA sequence:RefSeq:WP_011513978.1
SurA N-terminal domain-containing protein
The exact function of these proteins is not yet clear but they are capable of wrapping DNA and stabilizing it from denaturation under extreme environmental conditions.
COORDINATES: similar to AA sequence:RefSeq:WP_003531811.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443757.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280742.1
COORDINATES: similar to AA sequence:RefSeq:WP_003665735.1
GO:0031071 - cysteine desulfurase activity [Evidence IEA]; GO:0030170 - pyridoxal phosphate binding [Evidence IEA]
GO:0044571 - [2Fe-2S] cluster assembly [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020443759.1
COORDINATES: similar to AA sequence:RefSeq:WP_005178462.1
iron-sulfur cluster assembly protein IscA
COORDINATES: similar to AA sequence:RefSeq:WP_011513985.1
assisting folding newly translated proteins;guiding translocating proteins across organellar membranes; disassembling oligomeric protein structures;facilitating proteolytic degradation, etc...
COORDINATES: similar to AA sequence:RefSeq:WP_003665733.1
COORDINATES: similar to AA sequence:RefSeq:YP_004995265.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280749.1
DNA-dependent ATPases that function in the process of transcription-coupled DNA repair in which the repair of the transcribed strand of actively transcribed genes is repaired at a higher rate than the repair of non-transcribed regions of the genome
COORDINATES: similar to AA sequence:RefSeq:WP_020443763.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0016887 - ATP hydrolysis activity [Evidence IEA]; GO:0003690 - double-stranded DNA binding [Evidence IEA]; GO:0005515 - protein binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004701936.1
GO:0008428 - ribonuclease inhibitor activity [Evidence IEA]
GO:0051252 - regulation of RNA metabolic process [Evidence IEA]
closest fits to epimerases and dehydrogenases (38% identity) of carbohydtrate metabolism
COORDINATES: similar to AA sequence:RefSeq:WP_011513992.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513993.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443766.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513995.1
'de novo' Pyrmidine biosynthesis: Orotidine 5' phosphate to UMP.
COORDINATES: similar to AA sequence:RefSeq:WP_011513996.1
GO:0004590 - orotidine-5'-phosphate decarboxylase activity [Evidence IEA]
GO:0006207 - 'de novo' pyrimidine nucleobase biosynthetic process [Evidence IEA]; GO:0044205 - 'de novo' UMP biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011280757.1
lipopolysaccharide assembly protein LapA domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_020443770.1
GO:0006310 - DNA recombination [Evidence IEA]; GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020443771.1
Phosphorylates UMP, CMP or dCMP to U/CDP using ATP or GTP
COORDINATES: similar to AA sequence:RefSeq:WP_011280760.1
GO:0004127 - cytidylate kinase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_019672615.1
GO:0008251 - tRNA-specific adenosine deaminase activity [Evidence IEA]; GO:0008270 - zinc ion binding [Evidence IEA]
GO:0002100 - tRNA wobble adenosine to inosine editing [Evidence IEA]
Uracil-DNA glycosylase is a DNA repair enzyme that excises uracil residues from DNA by cleaving the N-glycosylic bond. Uracil in DNA can arise as a result of misincorportation of dUMP residues by DNA polymerase or deamination of cytosine.
COORDINATES: similar to AA sequence:RefSeq:WP_020443774.1
GO:0004844 - uracil DNA N-glycosylase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011514002.1
GO:0009368 - endopeptidase Clp complex [Evidence IEA]
GO:0004176 - ATP-dependent peptidase activity [Evidence IEA]
GO:0043335 - protein unfolding [Evidence IEA]; GO:0006508 - proteolysis [Evidence IEA]
ATP-dependent Clp protease ATP-binding subunit ClpA
Modifies substrate specifity of the ClpA chaperone. ClpA targets proteins for degradation.
COORDINATES: similar to AA sequence:RefSeq:WP_007395214.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514004.1
COORDINATES: similar to AA sequence:RefSeq:WP_005107142.1
GO:0003942 - N-acetyl-gamma-glutamyl-phosphate reductase activity [Evidence IEA]
N-acetyl-gamma-glutamyl-phosphate reductase
COORDINATES: similar to AA sequence:RefSeq:WP_010200147.1
GO:0004853 - uroporphyrinogen decarboxylase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011280768.1
GO:0004349 - glutamate 5-kinase activity [Evidence IEA]
uncertain function: but seems important in development and normal cell metabolism
COORDINATES: similar to AA sequence:RefSeq:WP_020443779.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514009.1
GO:0051287 - NAD binding [Evidence IEA]; GO:0050661 - NADP binding [Evidence IEA]; GO:0016620 - oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [Evidence IEA]
GO:0006006 - glucose metabolic process [Evidence IEA]
glyceraldehyde-3-phosphate dehydrogenase
COORDINATES: similar to AA sequence:RefSeq:WP_004840756.1
NUDIX hydrolases (NUcleoside DIphosphate linked to some other moiety X) hydrolyse diverse nucleoside diphosphate derivatives (including ADP-ribose, TDP-glucose, NADH, UDP-sugars, dNTP and NTP). MutT, anti- mutagenic activity, also shares this domain.
COORDINATES: similar to AA sequence:RefSeq:WP_020443782.1
COORDINATES: similar to AA sequence:RefSeq:WP_003657438.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280774.1
translocation/assembly module TamB domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_020443785.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514015.1
COORDINATES: similar to AA sequence:RefSeq:WP_004806468.1
GO:0004497 - monooxygenase activity [Evidence IEA]
2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone monooxygenase
COORDINATES: similar to AA sequence:RefSeq:WP_011514017.1
COORDINATES: similar to AA sequence:RefSeq:WP_010200186.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443790.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514020.1
GO:0016682 - oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor [Evidence IEA]
cytochrome d ubiquinol oxidase subunit II
Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis
COORDINATES: similar to AA sequence:RefSeq:WP_019520501.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514022.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280784.1
GO:0061024 - membrane organization [Evidence IEA]; GO:0010033 - response to organic substance [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011280785.1
COORDINATES: protein motif:HMM:NF012927.2
COORDINATES: similar to AA sequence:RefSeq:WP_011514025.1
Biosynthesis of Lysine, Diaminopimellate, Methionine, and Threonine from Aspartate.
COORDINATES: similar to AA sequence:RefSeq:WP_011514026.1
GO:0004073 - aspartate-semialdehyde dehydrogenase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020443802.1
GO:0008479 - queuine tRNA-ribosyltransferase activity [Evidence IEA]
sodium symporter activity, possible amino acid symporter
COORDINATES: similar to AA sequence:RefSeq:WP_011514029.1
COORDINATES: similar to AA sequence:RefSeq:WP_010200222.1
GO:0008780 - acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity [Evidence IEA]
GO:0008610 - lipid biosynthetic process [Evidence IEA]
acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_011280792.1
GO:0016836 - hydro-lyase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011514032.1
GO:0016410 - N-acyltransferase activity [Evidence IEA]
UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_011514033.1
outer membrane protein assembly factor BamA
Degradation of proteins, peptides, and glycopeptides
COORDINATES: similar to AA sequence:RefSeq:WP_011280795.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280796.1
GO:0030604 - 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity [Evidence IEA]; GO:0046872 - metal ion binding [Evidence IEA]; GO:0070402 - NADPH binding [Evidence IEA]; GO:0005515 - protein binding [Evidence IEA]
GO:0008299 - isoprenoid biosynthetic process [Evidence IEA]
1-deoxy-D-xylulose-5-phosphate reductoisomerase
COORDINATES: similar to AA sequence:RefSeq:WP_011514036.1
Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides. Used as a carrier in synthesizing cell wall components.
COORDINATES: similar to AA sequence:RefSeq:WP_011514037.1
releasing ribosomes from mRNA at the end of protein biosynthesis, it prevents inappropriate translation from 3-prime regions of the mRNA and frees the ribosome for new rounds of translation.
COORDINATES: similar to AA sequence:RefSeq:YP_004995726.1
GO:0008135 - translation factor activity, RNA binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011961019.1
GO:0033862 - UMP kinase activity [Evidence IEA]
Expected to modify bases in tRNA. Function unknown.
COORDINATES: similar to AA sequence:RefSeq:WP_011280801.1
GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; GO:1904047 - S-adenosyl-L-methionine binding [Evidence IEA]; GO:0008172 - S-methyltransferase activity [Evidence IEA]; GO:0016782 - transferase activity, transferring sulphur-containing groups [Evidence IEA]
GO:0018339 - peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid [Evidence IEA]
30S ribosomal protein S12 methylthiotransferase RimO
COORDINATES: similar to AA sequence:RefSeq:WP_020443810.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443811.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0008134 - transcription factor binding [Evidence IEA]
sigma 54-interacting transcriptional regulator
COORDINATES: similar to AA sequence:RefSeq:WP_020443812.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514044.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443815.1
growth-supporting role in biodegradative metabolism
COORDINATES: similar to AA sequence:RefSeq:WP_011514047.1
Topoisomerases are ubiquitous enzymes that catalyze cleavage and religation of DNA molecules allowing for the interconversion of topological isomers of DNA and play a key role in DNA metabolism.
COORDINATES: similar to AA sequence:RefSeq:WP_020443818.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0003677 - DNA binding [Evidence IEA]; GO:0003916 - DNA topoisomerase activity [Evidence IEA]; GO:0003918 - DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity [Evidence IEA]
GO:0006259 - DNA metabolic process [Evidence IEA]; GO:0006265 - DNA topological change [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020443819.1
COORDINATES: similar to AA sequence:RefSeq:WP_010200299.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514052.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514053.1
Fe(3+) ABC transporter substrate-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_020443823.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514055.1
3-deoxy-D-manno-octulosonic acid transferase
COORDINATES: similar to AA sequence:RefSeq:WP_011514056.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443826.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280817.1
GO:0000175 - 3'-5'-exoribonuclease activity [Evidence IEA]; GO:0003676 - nucleic acid binding [Evidence IEA]
GTPase within DUF258 domain also contains sigma 54 interactig domain o most likelyinvolved in transcritional reression or signal recieving
COORDINATES: similar to AA sequence:RefSeq:WP_010199247.1
GO:0005525 - GTP binding [Evidence IEA]; GO:0043022 - ribosome binding [Evidence IEA]
ribosome small subunit-dependent GTPase A
COORDINATES: similar to AA sequence:RefSeq:WP_010199245.1
rhodanese-like domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_011280820.1
GO:0015036 - disulfide oxidoreductase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010199239.1
GO:0051262 - protein tetramerization [Evidence IEA]; GO:0015031 - protein transport [Evidence IEA]
Purine metabolism, Phosphorylation of AMP to ADP.
COORDINATES: similar to AA sequence:RefSeq:WP_007115277.1
GO:0004017 - adenylate kinase activity [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020443830.1
GO:0017004 - cytochrome complex assembly [Evidence IEA]
c-type cytochrome biogenesis protein CcmI
COORDINATES: similar to AA sequence:RefSeq:WP_011514065.1
cytochrome c-type biogenesis protein CcmH
COORDINATES: similar to AA sequence:RefSeq:WP_011514066.1
DsbE family thiol:disulfide interchange protein
COORDINATES: similar to AA sequence:RefSeq:WP_011514067.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280827.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443835.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443836.1
GO:0052913 - 16S rRNA (guanine(966)-N(2))-methyltransferase activity [Evidence IEA]
16S rRNA (guanine(966)-N(2))-methyltransferase RsmD
COORDINATES: similar to AA sequence:RefSeq:WP_010847760.1
COORDINATES: similar to AA sequence:RefSeq:WP_000829824.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280832.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443839.1
GO:0004830 - tryptophan-tRNA ligase activity [Evidence IEA]
GO:0006436 - tryptophanyl-tRNA aminoacylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011514074.1
probable nucleotide binding due to presence of helix turn helix motif
COORDINATES: similar to AA sequence:RefSeq:WP_020443841.1
GO:0007059 - chromosome segregation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011514076.1
outer membrane lipoprotein chaperone LolA
COORDINATES: similar to AA sequence:RefSeq:WP_010199200.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280837.1
COORDINATES: similar to AA sequence:RefSeq:WP_003662556.1
part of RND multidrug/dye/detergent efflux pump
COORDINATES: similar to AA sequence:RefSeq:WP_011280839.1
COORDINATES: similar to AA sequence:RefSeq:WP_010199179.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514080.1
GO:0015288 - porin activity [Evidence IEA]
efflux transporter outer membrane subunit
COORDINATES: similar to AA sequence:RefSeq:WP_020443847.1
GO:0003824 - catalytic activity [Evidence IEA]; GO:0046872 - metal ion binding [Evidence IEA]; GO:0004655 - porphobilinogen synthase activity [Evidence IEA]
GO:0033014 - tetrapyrrole biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_000531189.1
COORDINATES: similar to AA sequence:RefSeq:WP_010201107.1
subtype I-F CRISPR-associated endonuclease Cas1
COORDINATES: similar to AA sequence:RefSeq:WP_063154576.1
COORDINATES: similar to AA sequence:RefSeq:WP_032676615.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514093.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443916.1
GO:0043953 - protein transport by the Tat complex [Evidence IEA]
Sec-independent protein translocase subunit TatA
COORDINATES: similar to AA sequence:RefSeq:WP_011514098.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443919.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280853.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513046.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513047.1
GO:0005507 - copper ion binding [Evidence IEA]; GO:0005375 - copper ion transmembrane transporter activity [Evidence IEA]
GO:0006825 - copper ion transport [Evidence IEA]
copper resistance system multicopper oxidase
COORDINATES: similar to AA sequence:RefSeq:WP_011959987.1
COORDINATES: similar to AA sequence:RefSeq:WP_011513049.1
COORDINATES: similar to AA sequence:RefSeq:WP_007117298.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443009.1
Chemotaxis. Members of this family contain a response regulator receiver domain (IPR001789) and an associated transcriptional regulatory region (IPR001867).
COORDINATES: similar to AA sequence:RefSeq:WP_011959983.1
heavy metal response regulator transcription factor
COORDINATES: similar to AA sequence:RefSeq:WP_011280861.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280862.1
HlyD family efflux transporter periplasmic adaptor subunit
COORDINATES: similar to AA sequence:RefSeq:WP_020443896.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443897.1
COORDINATES: protein motif:HMM:NF033510.3
COORDINATES: protein motif:HMM:NF012894.2
COORDINATES: similar to AA sequence:RefSeq:WP_011280868.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280869.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514154.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443976.1
COORDINATES: similar to AA sequence:RefSeq:WP_020443980.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514160.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514162.1
type I glyceraldehyde-3-phosphate dehydrogenase
AAA -This family is now called AAA, for ATPases Associated with diverse cellular Activities. The proteins that belong to this family either contain one or two AAA domains.
COORDINATES: similar to AA sequence:RefSeq:WP_020444030.1
COORDINATES: similar to AA sequence:RefSeq:WP_002049023.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444032.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514166.1
GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; GO:0016614 - oxidoreductase activity, acting on CH-OH group of donors [Evidence IEA]
GMC family oxidoreductase N-terminal domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_020444034.1
COORDINATES: protein motif:HMM:NF037930.2
glycolaldhydetransferase based on KEGG scores
COORDINATES: similar to AA sequence:RefSeq:WP_011280881.1
GO:0004802 - transketolase activity [Evidence IEA]
GO:0006098 - pentose-phosphate shunt [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011280882.1
GO:0004828 - serine-tRNA ligase activity [Evidence IEA]
GO:0006434 - seryl-tRNA aminoacylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020444038.1
A ferritin homolog that binds and protects DNA from oxidative damage.
COORDINATES: similar to AA sequence:RefSeq:WP_020444039.1
DNA starvation/stationary phase protection protein
COORDINATES: similar to AA sequence:RefSeq:WP_011280885.1
Initiation and regulation of chromosomal replication. DnaA is an ATP- and DNA-binding protein.
COORDINATES: similar to AA sequence:RefSeq:WP_011514174.1
GO:0016818 - hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [Evidence IEA]
GO:0032297 - negative regulation of DNA-templated DNA replication initiation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010196390.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444044.1
GO:0004641 - phosphoribosylformylglycinamidine cyclo-ligase activity [Evidence IEA]
phosphoribosylformylglycinamidine cyclo-ligase
'de novo' Purine synthesis: Biosynthesis of Inosine monophosphate
COORDINATES: similar to AA sequence:RefSeq:WP_019673677.1
GO:0004644 - phosphoribosylglycinamide formyltransferase activity [Evidence IEA]
phosphoribosylglycinamide formyltransferase
Bind DNA via a helix-turn-helix (HTH) motif.The majority of these proteins appear to be transcription activators and most are known to negatively regulate their own expression.
COORDINATES: similar to AA sequence:RefSeq:WP_011514179.1
COORDINATES: similar to AA sequence:RefSeq:WP_010196379.1
GO:0004451 - isocitrate lyase activity [Evidence IEA]
GO:0019752 - carboxylic acid metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011280892.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514182.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514183.1
COORDINATES: similar to AA sequence:RefSeq:WP_010196371.1
GO:0004055 - argininosuccinate synthase activity [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA]
Pyrimidine biosynthesis: Biosyntheis of Uridine monophosphate
COORDINATES: similar to AA sequence:RefSeq:WP_011514185.1
GO:0004151 - dihydroorotase activity [Evidence IEA]
RNase T removes the terminal AMP residue from uncharged tRNA. Inolved in RNA maturation and acts as a 3' to 5' single-strand DNA-specific exonuclease (distinctive for ability to remove residues near a double-stranded stem).
COORDINATES: similar to AA sequence:RefSeq:WP_020444050.1
GO:0016896 - exoribonuclease activity, producing 5'-phosphomonoesters [Evidence IEA]
GO:0006364 - rRNA processing [Evidence IEA]; GO:0042780 - tRNA 3'-end processing [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011280898.1
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_011514189.1
septum formation initiator family protein
catalyses the interconversion of 2-phosphoglycerate and phosphoenolpyruvate
COORDINATES: similar to AA sequence:RefSeq:WP_007395288.1
GO:0004634 - phosphopyruvate hydratase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011514191.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280902.1
possible heavy metal associated protein, weak hits to copZ and heavy metal ATPases
COORDINATES: similar to AA sequence:RefSeq:WP_011514193.1
heavy-metal-associated domain-containing protein
Involved in ketodeoxyoctanoate biosynthesis: Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides.
COORDINATES: similar to AA sequence:RefSeq:WP_010196356.1
GO:0008676 - 3-deoxy-8-phosphooctulonate synthase activity [Evidence IEA]
CTP biosynthesis from UTP and ammonium (from glutamine)
COORDINATES: similar to AA sequence:RefSeq:WP_020444056.1
GO:0003883 - CTP synthase activity [Evidence IEA]
GO:0006241 - CTP biosynthetic process [Evidence IEA]; GO:0006221 - pyrimidine nucleotide biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020444057.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444059.1
GO:0004474 - malate synthase activity [Evidence IEA]
GO:0006097 - glyoxylate cycle [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020444060.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444061.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444062.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514202.1
GO:0009358 - polyphosphate kinase complex [Evidence IEA]
GO:0006799 - polyphosphate biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011514203.1
GO:0016020 - membrane [Evidence IEA]; GO:0009274 - peptidoglycan-based cell wall [Evidence IEA]
monofunctional biosynthetic peptidoglycan transglycosylase
COORDINATES: similar to AA sequence:RefSeq:WP_011514204.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514205.1
GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; GO:0016491 - oxidoreductase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011280915.1
GO:0071949 - FAD binding [Evidence IEA]; GO:0016491 - oxidoreductase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020444067.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444068.1
COORDINATES: similar to AA sequence:RefSeq:WP_011960899.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514210.1
possibly acts as a scaffolding agent for subunits of a murein sacculus-synthesizing holoenzyme
COORDINATES: similar to AA sequence:RefSeq:WP_011514211.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444074.1
GO:0004333 - fumarate hydratase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011514215.1
GO:0030272 - 5-formyltetrahydrofolate cyclo-ligase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011514216.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514219.1
GO:0016887 - ATP hydrolysis activity [Evidence IEA]; GO:0004176 - ATP-dependent peptidase activity [Evidence IEA]; GO:0043565 - sequence-specific DNA binding [Evidence IEA]; GO:0004252 - serine-type endopeptidase activity [Evidence IEA]
DNA topoisomerase I catalyses the ATP-independent breakage of single-stranded DNA, followed by passage and rejoining of another single-stranded DNA region. Relaxes negatively supercoiled DNA during replication, transcription and recombination events.
COORDINATES: similar to AA sequence:RefSeq:WP_011514221.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0003917 - DNA topoisomerase type I (single strand cut, ATP-independent) activity [Evidence IEA]
GO:0006260 - DNA replication [Evidence IEA]; GO:0006265 - DNA topological change [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020444081.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280926.1
COORDINATES: similar to AA sequence:RefSeq:WP_019518584.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444084.1
GO:0015291 - secondary active transmembrane transporter activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011514234.1
COORDINATES: similar to AA sequence:RefSeq:WP_010201067.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444098.1
anthranilate synthase component I family protein
COORDINATES: similar to AA sequence:RefSeq:WP_020444099.1
Glutamate metabolism, Nitrogen metabolism
COORDINATES: similar to AA sequence:RefSeq:WP_020444107.1
GO:0016639 - oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [Evidence IEA]
GO:0006520 - amino acid metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011960298.1
GO:0004024 - alcohol dehydrogenase activity, zinc-dependent [Evidence IEA]; GO:0051903 - S-(hydroxymethyl)glutathione dehydrogenase activity [Evidence IEA]
GO:0006113 - fermentation [Evidence IEA]; GO:0009404 - toxin metabolic process [Evidence IEA]
S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase
COORDINATES: similar to AA sequence:RefSeq:WP_020444113.1
COORDINATES: similar to AA sequence:RefSeq:WP_010201313.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514263.1
DUF3488 and transglutaminase-like domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_020444117.1
this may be a magnesium chelatase/ATPase that is involved in assembling the methanol dehydrogenase
COORDINATES: similar to AA sequence:RefSeq:WP_020444118.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514266.1
dual function sensor, contains a PAS-like sensory box to regulate the diguanylate cyclase and phosphodiesterase A domains
COORDINATES: similar to AA sequence:RefSeq:WP_020444120.1
GGDEF domain-containing phosphodiesterase
COORDINATES: similar to AA sequence:RefSeq:WP_011514269.1
GO:0072581 - protein-N6-(L-lysyl)-L-lysine modification to protein-N6-(beta-lysyl)-L-lysine [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011280944.1
Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis
COORDINATES: similar to AA sequence:RefSeq:WP_011280945.1
tRNA threonylcarbamoyladenosine dehydratase
This family of proteins are related to a large superfamily of metalloenzymes. TatD, a member of this family has been shown experimentally to be a DNase enzyme.
COORDINATES: similar to AA sequence:RefSeq:WP_011514273.1
Binds single-stranded DNA and plays an important role in DNA replication, recombination and repair.
COORDINATES: similar to AA sequence:RefSeq:WP_010114967.1
GO:0003697 - single-stranded DNA binding [Evidence IEA]
GO:0006310 - DNA recombination [Evidence IEA]; GO:0006281 - DNA repair [Evidence IEA]; GO:0006260 - DNA replication [Evidence IEA]; GO:0006351 - DNA-templated transcription [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011514279.1
UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair.
COORDINATES: similar to AA sequence:RefSeq:WP_010201350.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0016887 - ATP hydrolysis activity [Evidence IEA]; GO:0003677 - DNA binding [Evidence IEA]
COORDINATES: protein motif:HMM:NF025639.2
COORDINATES: protein motif:HMM:NF016351.2
COORDINATES: similar to AA sequence:RefSeq:WP_011514284.1
threonine/serine exporter family protein
Possible membrane protein: has 4 TM domains
COORDINATES: similar to AA sequence:RefSeq:WP_010201359.1
Glutathione metabolism, Glutamate metabolism
COORDINATES: similar to AA sequence:RefSeq:WP_013107696.1
GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; GO:0004362 - glutathione-disulfide reductase (NADPH) activity [Evidence IEA]; GO:0050661 - NADP binding [Evidence IEA]
GO:0045454 - cell redox homeostasis [Evidence IEA]; GO:0006749 - glutathione metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020444140.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280958.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444144.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514294.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514295.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514296.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280963.1
GO:0016645 - oxidoreductase activity, acting on the CH-NH group of donors [Evidence IEA]
tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD
COORDINATES: similar to AA sequence:RefSeq:WP_020444149.1
GO:0008412 - 4-hydroxybenzoate octaprenyltransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011514301.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514302.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444152.1
GO:0050380 - undecaprenyl-diphosphatase activity [Evidence IEA]
GO:0016311 - dephosphorylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010201394.1
GO:0003725 - double-stranded RNA binding [Evidence IEA]
tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB
COORDINATES: similar to AA sequence:RefSeq:WP_003657561.1
GO:0048501 - signal recognition particle, plasma membrane targeting [Evidence IEA]
GO:0003924 - GTPase activity [Evidence IEA]; GO:0005048 - signal sequence binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011514306.1
GO:0020037 - heme binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020442976.1
COORDINATES: similar to AA sequence:RefSeq:YP_004997628.1
COORDINATES: similar to AA sequence:RefSeq:YP_004997627.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514309.1
COORDINATES: similar to AA sequence:RefSeq:WP_003659938.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444159.1
converts D-ribulose 5-phosphate into D-xylulose 5-phosphate in Calvin's reductive pentose phosphate cycle.
COORDINATES: similar to AA sequence:RefSeq:WP_011514312.1
GO:0004750 - D-ribulose-phosphate 3-epimerase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020444161.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514314.1
GO:0018738 - S-formylglutathione hydrolase activity [Evidence IEA]
GO:0046292 - formaldehyde metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020444163.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280980.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0016887 - ATP hydrolysis activity [Evidence IEA]; GO:0051082 - unfolded protein binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011280981.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514319.1
COORDINATES: similar to AA sequence:RefSeq:WP_010201433.1
GO:0051745 - 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity [Evidence IEA]; GO:0046872 - metal ion binding [Evidence IEA]
GO:0050992 - dimethylallyl diphosphate biosynthetic process [Evidence IEA]; GO:0019288 - isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway [Evidence IEA]
4-hydroxy-3-methylbut-2-enyl diphosphate reductase
Phosphorylation of GMP to GDP using ATP.
COORDINATES: similar to AA sequence:RefSeq:WP_011514321.1
GO:0004385 - guanylate kinase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010201435.1
GO:0000345 - cytosolic DNA-directed RNA polymerase complex [Evidence IEA]
GO:0003899 - DNA-directed 5'-3' RNA polymerase activity [Evidence IEA]
DNA-directed RNA polymerase subunit omega
COORDINATES: similar to AA sequence:RefSeq:WP_011280986.1
COORDINATES: similar to AA sequence:RefSeq:WP_016782709.1
COORDINATES: similar to AA sequence:RefSeq:WP_010201438.1
GO:0003678 - DNA helicase activity [Evidence IEA]
GO:0032508 - DNA duplex unwinding [Evidence IEA]; GO:0006260 - DNA replication [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020444173.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514328.1
GO:0005451 - monovalent cation:proton antiporter activity [Evidence IEA]
GO:0006812 - cation transport [Evidence IEA]; GO:1902600 - proton transmembrane transport [Evidence IEA]
monovalent cation:proton antiporter-2 (CPA2) family protein
COORDINATES: similar to AA sequence:RefSeq:WP_020444175.1
COORDINATES: similar to AA sequence:RefSeq:WP_011280992.1
GO:0008176 - tRNA (guanine-N7-)-methyltransferase activity [Evidence IEA]
tRNA (guanosine(46)-N7)-methyltransferase TrmB
RecA plays a role in homologous recombination, DNA repair and induction of the SOS response. In homologous recombination, RecA functions as a DNA-dependent ATPase, promoting synapsis, heteroduplex formation and strand exchange between homologous DNAs.
COORDINATES: similar to AA sequence:RefSeq:WP_010201447.1
GO:0008094 - ATP-dependent activity, acting on DNA [Evidence IEA]; GO:0003677 - DNA binding [Evidence IEA]
GO:0006310 - DNA recombination [Evidence IEA]; GO:0006281 - DNA repair [Evidence IEA]; GO:0009432 - SOS response [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020444177.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444178.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444179.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514335.1
succinate dehydrogenase assembly factor 2
COORDINATES: similar to AA sequence:RefSeq:WP_010201455.1
GO:0004156 - dihydropteroate synthase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011280999.1
GO:0016887 - ATP hydrolysis activity [Evidence IEA]; GO:0004222 - metalloendopeptidase activity [Evidence IEA]
GO:0051301 - cell division [Evidence IEA]; GO:0006508 - proteolysis [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_003659062.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444184.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514340.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514341.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514342.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444187.1
GO:0008759 - UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity [Evidence IEA]
UDP-3-O-acyl-N-acetylglucosamine deacetylase
COORDINATES: similar to AA sequence:RefSeq:WP_011514344.1
COORDINATES: similar to AA sequence:RefSeq:WP_019671734.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0005515 - protein binding [Evidence IEA]
GO:0043093 - FtsZ-dependent cytokinesis [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011514346.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444190.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514348.1
GO:0008763 - UDP-N-acetylmuramate-L-alanine ligase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020444192.1
GO:0050511 - undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity [Evidence IEA]
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_020444193.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0004363 - glutathione synthase activity [Evidence IEA]; GO:0046872 - metal ion binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020444194.1
GO:0004588 - orotate phosphoribosyltransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011514352.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514353.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444197.1
peptidoglycan catabolism: N-acetylmuramoyl-L-alanine amidase activity
COORDINATES: similar to AA sequence:RefSeq:WP_011514355.1
GO:0008745 - N-acetylmuramoyl-L-alanine amidase activity [Evidence IEA]
GO:0009253 - peptidoglycan catabolic process [Evidence IEA]
1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD
mviN virulence genes are 12 TM spanning proteins related to the Multidrug/Oligosaccharidyl-lipid/Polysaccharide (MOP) Flippase Superfamily
COORDINATES: similar to AA sequence:RefSeq:WP_003673659.1
GO:0034204 - lipid translocation [Evidence IEA]; GO:0009252 - peptidoglycan biosynthetic process [Evidence IEA]
murein biosynthesis integral membrane protein MurJ
COORDINATES: similar to AA sequence:RefSeq:WP_011514357.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444202.1
COORDINATES: similar to AA sequence:RefSeq:WP_011281021.1
GO:0003919 - FMN adenylyltransferase activity [Evidence IEA]
bifunctional riboflavin kinase/FAD synthetase
COORDINATES: similar to AA sequence:RefSeq:WP_011514360.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514361.1
GO:0016615 - malate dehydrogenase activity [Evidence IEA]
GO:0006108 - malate metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020444206.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444207.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444208.1
GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; GO:1904047 - S-adenosyl-L-methionine binding [Evidence IEA]; GO:0016782 - transferase activity, transferring sulphur-containing groups [Evidence IEA]
tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB
COORDINATES: similar to AA sequence:RefSeq:WP_020444209.1
Arginine biosynthesis, Metabolism of Amino groups.
COORDINATES: similar to AA sequence:RefSeq:WP_011514366.1
GO:0008777 - acetylornithine deacetylase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007395539.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514369.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514370.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444214.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444215.1
GO:0009345 - glycine-tRNA ligase complex [Evidence IEA]
GO:0004820 - glycine-tRNA ligase activity [Evidence IEA]
GO:0006426 - glycyl-tRNA aminoacylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010201516.1
activates psp operon expression, see citation, possible leucine zipper for protein interaction 2 possible TM domains instead - possible receptor?
COORDINATES: similar to AA sequence:RefSeq:WP_011514374.1
COORDINATES: protein motif:HMM:NF017897.2
possible oxidoreductase related to nitroreductase (COG3560) possible signal transduction protein involved in regulating fatty acid metabolism, see yeast genes
COORDINATES: similar to AA sequence:RefSeq:WP_011513876.1
COORDINATES: similar to AA sequence:RefSeq:WP_076611454.1
COORDINATES: similar to AA sequence:RefSeq:WP_076611460.1
IS3-like element ISPar2 family transposase
COORDINATES: protein motif:HMM:NF017658.2
filamentous hemagglutinin N-terminal domain-containing protein
involved in secretion of heme-hemopexin utilization protein A
COORDINATES: protein motif:HMM:NF015803.2
ShlB/FhaC/HecB family hemolysin secretion/activation protein
COORDINATES: similar to AA sequence:RefSeq:WP_011514379.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514380.1
COORDINATES: similar to AA sequence:RefSeq:WP_011281045.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514382.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514383.1
Essential for natural transformation and could be a transporter involved in DNA uptake.
COORDINATES: similar to AA sequence:RefSeq:WP_020444224.1
COORDINATES: similar to AA sequence:RefSeq:WP_007393842.1
contains antisigma-factor antagonist (STAS) domain
COORDINATES: similar to AA sequence:RefSeq:WP_020444226.1
GO:0015116 - sulfate transmembrane transporter activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010201552.1
possible sulfide dehydrogenase (flavocytochrome c) due to one of the top blast hits, but this has no reference to back it up
COORDINATES: similar to AA sequence:RefSeq:WP_011281053.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444231.1
GO:0016668 - oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor [Evidence IEA]
GO:0009398 - FMN biosynthetic process [Evidence IEA]; GO:0006805 - xenobiotic metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020444232.1
Responsible for directly reducing organic hyperoxides in its reduced dithiol form.
COORDINATES: similar to AA sequence:RefSeq:WP_003656441.1
GO:0102039 - NADH-dependent peroxiredoxin activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010201564.1
hydrogen peroxide-inducible genes activator
COORDINATES: similar to AA sequence:RefSeq:WP_020444235.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444236.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444237.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444238.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444239.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514401.1
COORDINATES: protein motif:HMM:NF024879.2
YMGG-like glycine zipper-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_020444243.1
COORDINATES: similar to AA sequence:RefSeq:WP_011281066.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444245.1
GO:0004857 - enzyme inhibitor activity [Evidence IEA]
GO:0000918 - division septum site selection [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_019520449.1
COORDINATES: similar to AA sequence:RefSeq:WP_011281069.1
GO:0032955 - regulation of division septum assembly [Evidence IEA]
cell division topological specificity factor MinE
COORDINATES: similar to AA sequence:RefSeq:WP_011514408.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514409.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444249.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444250.1
COORDINATES: similar to AA sequence:RefSeq:WP_003100940.1
COORDINATES: similar to AA sequence:RefSeq:WP_011281075.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514415.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514416.1
twitching motility response regulator PilG
COORDINATES: similar to AA sequence:RefSeq:WP_011514417.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514418.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514419.1
COORDINATES: similar to AA sequence:RefSeq:WP_011281081.1
methionine ABC transporter ATP-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_011281082.1
COORDINATES: similar to AA sequence:RefSeq:WP_007393638.1
MetQ/NlpA family ABC transporter substrate-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_011514424.1
GO:0017004 - cytochrome complex assembly [Evidence IEA]; GO:0017003 - protein-heme linkage [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011514425.1
GO:0017004 - cytochrome complex assembly [Evidence IEA]; GO:0015886 - heme transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011514426.1
GO:0015232 - heme transmembrane transporter activity [Evidence IEA]
GO:0015886 - heme transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011961378.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444262.1
GO:0015439 - ABC-type heme transporter activity [Evidence IEA]
heme ABC exporter ATP-binding protein CcmA
COORDINATES: similar to AA sequence:RefSeq:WP_010201642.1
COORDINATES: similar to AA sequence:RefSeq:WP_003659195.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444266.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444267.1
GO:0004632 - phosphopantothenate--cysteine ligase activity [Evidence IEA]; GO:0004633 - phosphopantothenoylcysteine decarboxylase activity [Evidence IEA]
GO:0015937 - coenzyme A biosynthetic process [Evidence IEA]; GO:0015939 - pantothenate metabolic process [Evidence IEA]
bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC
RadC plays a role in repair of DNA damage after UV and X-ray irradiation in prokaryotes.
COORDINATES: similar to AA sequence:RefSeq:WP_010201649.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514435.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444271.1
dicarboxylate/amino acid:cation symporter
COORDINATES: similar to AA sequence:RefSeq:WP_011514437.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514438.1
GO:0015385 - sodium:proton antiporter activity [Evidence IEA]
GO:1902600 - proton transmembrane transport [Evidence IEA]; GO:0006814 - sodium ion transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020444273.1
Nudix family:hydrolyse diverse nucleoside diphosphate derivatives. MutT:remove an oxidatively damaged form of guanine from DNA and the nucleotide pool
COORDINATES: similar to AA sequence:RefSeq:WP_020444274.1
hydrolyse diverse nucleoside diphosphate derivatives
COORDINATES: similar to AA sequence:RefSeq:WP_011281100.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514444.1
Adaptation to atypical conditions, specially when conditions cause growth arrest (ex. stationary phase)
COORDINATES: similar to AA sequence:RefSeq:WP_011514445.1
COORDINATES: similar to AA sequence:RefSeq:WP_010201659.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514447.1
YeiH family putative sulfate export transporter
COORDINATES: similar to AA sequence:RefSeq:WP_004648869.1
COORDINATES: similar to AA sequence:RefSeq:WP_011281105.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444282.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514452.1
GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]; GO:0005524 - ATP binding [Evidence IEA]; GO:0000166 - nucleotide binding [Evidence IEA]; GO:0004832 - valine-tRNA ligase activity [Evidence IEA]
GO:0006438 - valyl-tRNA aminoacylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011514453.1
formate/nitrite transporter family protein
COORDINATES: similar to AA sequence:RefSeq:WP_020444288.1
heavy metal-binding domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_011281111.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444290.1
COORDINATES: similar to AA sequence:RefSeq:WP_011281113.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514458.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444292.1
GO:0036424 - L-phosphoserine phosphatase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020444293.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514461.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514462.1
Catalyzes the last step of the biotin biosynthesis pathway
COORDINATES: similar to AA sequence:RefSeq:WP_011281119.1
GO:0051537 - 2 iron, 2 sulfur cluster binding [Evidence IEA]; GO:0051539 - 4 iron, 4 sulfur cluster binding [Evidence IEA]; GO:0004076 - biotin synthase activity [Evidence IEA]; GO:1904047 - S-adenosyl-L-methionine binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010201681.1
Possible secreted protein due to the presence of a signal peptide
COORDINATES: similar to AA sequence:RefSeq:WP_011514465.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514466.1
COORDINATES: similar to AA sequence:RefSeq:WP_009584291.1
GO:0004549 - tRNA-specific ribonuclease activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_007395900.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514469.1
Topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation.
COORDINATES: similar to AA sequence:RefSeq:WP_007395902.1
GO:0009340 - DNA topoisomerase IV complex [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004754290.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444303.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444305.1
COORDINATES: similar to AA sequence:RefSeq:WP_010201700.1
Glutamate biosynthesis, Nitrogen metabolism
COORDINATES: similar to AA sequence:RefSeq:YP_004996920.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444309.1
GO:0003824 - catalytic activity [Evidence IEA]; GO:0015930 - glutamate synthase activity [Evidence IEA]; GO:0016491 - oxidoreductase activity [Evidence IEA]
GO:0006537 - glutamate biosynthetic process [Evidence IEA]; GO:0006807 - nitrogen compound metabolic process [Evidence IEA]
Possible secreted protein, because it has a signal peptide present
COORDINATES: similar to AA sequence:RefSeq:WP_011514479.1
Phenylalanine, Tyrosine, Tryptophan Metabolism, Shikimate Pathway
COORDINATES: similar to AA sequence:RefSeq:WP_011281135.1
GO:0003856 - 3-dehydroquinate synthase activity [Evidence IEA]
Phenylalanine, Tyrosine and Tryptophan metabolism
COORDINATES: similar to AA sequence:RefSeq:WP_011514481.1
forms outer membrane pore for protein secretion
COORDINATES: similar to AA sequence:RefSeq:WP_011514482.1
GO:0009297 - pilus assembly [Evidence IEA]; GO:0009306 - protein secretion [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011514483.1
COORDINATES: similar to AA sequence:RefSeq:WP_010201707.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514485.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514486.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444317.1
GO:0008658 - penicillin binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011514488.1
COORDINATES: similar to AA sequence:RefSeq:WP_011281144.1
DNA-directed RNA polymerase subunit beta'
COORDINATES: similar to AA sequence:RefSeq:WP_011281145.1
DNA-directed RNA polymerase subunit beta
COORDINATES: similar to AA sequence:RefSeq:WP_011281146.1
COORDINATES: similar to AA sequence:RefSeq:WP_002438625.1
GO:0015934 - large ribosomal subunit [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_003656500.1
COORDINATES: similar to AA sequence:RefSeq:WP_007395730.1
NusG is a bacterial transcriptional elongation factor involved in transcription termination and anti-termination
COORDINATES: similar to AA sequence:RefSeq:WP_003658755.1
transcription termination/antitermination protein NusG
COORDINATES: similar to AA sequence:RefSeq:WP_020444319.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514496.1
COORDINATES: similar to AA sequence:RefSeq:WP_001742319.1
COORDINATES: similar to AA sequence:RefSeq:WP_011281154.1
COORDINATES: similar to AA sequence:RefSeq:WP_010200612.1
COORDINATES: similar to AA sequence:RefSeq:WP_016142012.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444322.1
Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism and biosynthesis
COORDINATES: similar to AA sequence:RefSeq:WP_020444323.1
COORDINATES: similar to AA sequence:RefSeq:WP_017387694.1
GO:0004399 - histidinol dehydrogenase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011281160.1
GO:0003879 - ATP phosphoribosyltransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011281161.1
GO:0008760 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity [Evidence IEA]
UDP-N-acetylglucosamine 1-carboxyvinyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_011514505.1
BolA/IbaG family iron-sulfur metabolism protein
COORDINATES: similar to AA sequence:RefSeq:WP_020444327.1
COORDINATES: protein motif:HMM:NF016836.2
COORDINATES: similar to AA sequence:RefSeq:WP_011281165.1
GO:0004518 - nuclease activity [Evidence IEA]; GO:0003676 - nucleic acid binding [Evidence IEA]
methyltransferase activity; enzyme specific to the cobalamin pathway and precorrin-2 is a common intermediate in the biosynthesis of corrinoids such as vitamin B12, siroheme and coenzyme F430
COORDINATES: similar to AA sequence:RefSeq:WP_010200629.1
GO:0008649 - rRNA methyltransferase activity [Evidence IEA]; GO:0008757 - S-adenosylmethionine-dependent methyltransferase activity [Evidence IEA]
GO:0000451 - rRNA 2'-O-methylation [Evidence IEA]
16S rRNA (cytidine(1402)-2'-O)-methyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_020444331.1
Thought to be responsible for Fe-S center assembly of nitrogenase
COORDINATES: similar to AA sequence:RefSeq:WP_020444333.1
COORDINATES: similar to AA sequence:RefSeq:WP_020204500.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444335.1
bifunctional nicotinamide-nucleotide adenylyltransferase/Nudix hydroxylase
COORDINATES: similar to AA sequence:RefSeq:WP_010200637.1
COORDINATES: similar to AA sequence:RefSeq:WP_011281172.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514517.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444338.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444339.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514520.1
COORDINATES: similar to AA sequence:RefSeq:WP_010200649.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444344.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514525.1
GO:0000155 - phosphorelay sensor kinase activity [Evidence IEA]
GO:0006796 - phosphate-containing compound metabolic process [Evidence IEA]; GO:0000160 - phosphorelay signal transduction system [Evidence IEA]
phosphate regulon sensor histidine kinase PhoR
COORDINATES: similar to AA sequence:RefSeq:WP_010200659.1
GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; GO:0000156 - phosphorelay response regulator activity [Evidence IEA]
GO:0006796 - phosphate-containing compound metabolic process [Evidence IEA]; GO:0000160 - phosphorelay signal transduction system [Evidence IEA]; GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]
phosphate regulon transcriptional regulator PhoB
This homodimeric enzyme appears able to cleave any D-amino acid (and glycine, which does not have distinct D/L forms) from charged tRNA. The name reflects characterization with respect to D-Tyr on tRNA(Tyr) as established in the literature, but substrate
COORDINATES: similar to AA sequence:RefSeq:WP_011281181.1
Gly/Thr/Ser metabolism & glycerolipid metabolism
COORDINATES: similar to AA sequence:RefSeq:WP_003656838.1
GO:0004609 - phosphatidylserine decarboxylase activity [Evidence IEA]
Phosphatidylserine decarboxylase is synthesized as a single chain precursor. Generation of the pyruvoyl active site from a Ser is coupled to cleavage of a Gly-Ser bond between the larger (beta) and smaller (alpha chains). It is an integral membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_011281183.1
GO:0042301 - phosphate ion binding [Evidence IEA]
GO:0035435 - phosphate ion transmembrane transport [Evidence IEA]
phosphate ABC transporter substrate-binding protein PstS
COORDINATES: similar to AA sequence:RefSeq:WP_007394932.1
GO:0015415 - ATPase-coupled phosphate ion transmembrane transporter activity [Evidence IEA]
phosphate ABC transporter permease subunit PstC
COORDINATES: similar to AA sequence:RefSeq:WP_011514531.1
COORDINATES: similar to AA sequence:RefSeq:WP_005171697.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0015415 - ATPase-coupled phosphate ion transmembrane transporter activity [Evidence IEA]
phosphate ABC transporter ATP-binding protein PstB
COORDINATES: similar to AA sequence:RefSeq:WP_011281187.1
GO:0051049 - regulation of transport [Evidence IEA]
phosphate signaling complex protein PhoU
COORDINATES: similar to AA sequence:RefSeq:WP_010200665.1
COORDINATES: similar to AA sequence:RefSeq:WP_010200667.1
3-ketoacyl-CoA thiolase (also called thiolase I) has a broad chain-length specificity for its substrates and is involved in degradative pathways such as fatty acid beta-oxidation.
COORDINATES: similar to AA sequence:RefSeq:WP_000212712.1
GO:0003988 - acetyl-CoA C-acyltransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011281191.1
GO:0070403 - NAD+ binding [Evidence IEA]; GO:0016491 - oxidoreductase activity [Evidence IEA]
fatty acid oxidation complex subunit alpha FadB
COORDINATES: similar to AA sequence:RefSeq:WP_020444350.1
The function of the DUF72 family is unknown. Aquifex aeolicus has two copies of this protein. A probable aspartyl-tRNA synthetase from Escherichia coli [1] belongs to this group
COORDINATES: similar to AA sequence:RefSeq:WP_010200675.1
COORDINATES: protein motif:HMM:NF017519.2
YiiX/YebB-like N1pC/P60 family cysteine hydrolase
COORDINATES: similar to AA sequence:RefSeq:WP_010200680.1
protects the cell from HAP (base analog 6-N-hydroxylaminopurine), either on the level of deoxynucleoside triphosphate or the DNA level
COORDINATES: similar to AA sequence:RefSeq:WP_020444353.1
RdgB/HAM1 family non-canonical purine NTP pyrophosphatase
COORDINATES: similar to AA sequence:RefSeq:WP_011514543.1
GO:0005854 - nascent polypeptide-associated complex [Evidence IEA]
GO:0003755 - peptidyl-prolyl cis-trans isomerase activity [Evidence IEA]; GO:0051082 - unfolded protein binding [Evidence IEA]
GO:0051083 - 'de novo' cotranslational protein folding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010200686.1
GO:0004176 - ATP-dependent peptidase activity [Evidence IEA]; GO:0004252 - serine-type endopeptidase activity [Evidence IEA]
ATP-dependent Clp endopeptidase proteolytic subunit ClpP
COORDINATES: similar to AA sequence:RefSeq:WP_011959594.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0004252 - serine-type endopeptidase activity [Evidence IEA]; GO:0051082 - unfolded protein binding [Evidence IEA]
ATP-dependent protease ATP-binding subunit ClpX
COORDINATES: similar to AA sequence:RefSeq:WP_011514546.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514547.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444357.1
GO:0042834 - peptidoglycan binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011281203.1
GO:0004814 - arginine-tRNA ligase activity [Evidence IEA]
GO:0006420 - arginyl-tRNA aminoacylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020444359.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444360.1
GO:0002098 - tRNA wobble uridine modification [Evidence IEA]
tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB
COORDINATES: similar to AA sequence:RefSeq:WP_011281206.1
carboxy-S-adenosyl-L-methionine synthase CmoA
COORDINATES: similar to AA sequence:RefSeq:WP_020444362.1
COORDINATES: protein motif:HMM:NF019032.2
COORDINATES: similar to AA sequence:RefSeq:WP_011514556.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514557.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444367.1
GO:0008881 - glutamate racemase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011514560.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444369.1
electron transfer flavoprotein-ubiquinone oxidoreductase
COORDINATES: protein motif:HMM:NF013406.2
COORDINATES: similar to AA sequence:RefSeq:WP_015869530.1
COORDINATES: similar to AA sequence:RefSeq:WP_076611762.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514563.1
COORDINATES: similar to AA sequence:RefSeq:WP_003673986.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514565.1
COORDINATES: protein motif:HMM:NF017953.2
COORDINATES: similar to AA sequence:RefSeq:WP_011514569.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444374.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444376.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444377.1
GO:0004845 - uracil phosphoribosyltransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011514573.1
COORDINATES: similar to AA sequence:RefSeq:WP_010197803.1
COORDINATES: similar to AA sequence:RefSeq:WP_011281226.1
GO:0004831 - tyrosine-tRNA ligase activity [Evidence IEA]
GO:0006437 - tyrosyl-tRNA aminoacylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011514579.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0016773 - phosphotransferase activity, alcohol group as acceptor [Evidence IEA]
GO:0006040 - amino sugar metabolic process [Evidence IEA]; GO:0009254 - peptidoglycan turnover [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020444386.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514581.1
COORDINATES: similar to AA sequence:RefSeq:WP_011281230.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444390.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514585.1
GO:0042158 - lipoprotein biosynthetic process [Evidence IEA]; GO:0006497 - protein lipidation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011281233.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444392.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514589.1
COORDINATES: similar to AA sequence:RefSeq:WP_011281236.1
COORDINATES: similar to AA sequence:RefSeq:WP_010197827.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444397.1
GO:0006310 - DNA recombination [Evidence IEA]; GO:0006281 - DNA repair [Evidence IEA]; GO:0006260 - DNA replication [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011281240.1
COORDINATES: similar to AA sequence:RefSeq:WP_010197841.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0140658 - ATP-dependent chromatin remodeler activity [Evidence IEA]; GO:0016817 - hydrolase activity, acting on acid anhydrides [Evidence IEA]
L-serine biosynthesis: Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
COORDINATES: similar to AA sequence:RefSeq:WP_020444403.1
COORDINATES: similar to AA sequence:RefSeq:WP_003663606.1
COORDINATES: similar to AA sequence:RefSeq:WP_003657354.1
COORDINATES: similar to AA sequence:RefSeq:WP_019838192.1
GO:0008186 - ATP-dependent activity, acting on RNA [Evidence IEA]; GO:0004386 - helicase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011514602.1
glycine zipper 2TM domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_020444408.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444409.1
COORDINATES: similar to AA sequence:RefSeq:WP_011281249.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444410.1
GO:0009328 - phenylalanine-tRNA ligase complex [Evidence IEA]
GO:0004826 - phenylalanine-tRNA ligase activity [Evidence IEA]
GO:0006432 - phenylalanyl-tRNA aminoacylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011281251.1
phenylalanine--tRNA ligase subunit alpha
COORDINATES: similar to AA sequence:RefSeq:WP_003661132.1
COORDINATES: similar to AA sequence:RefSeq:WP_011281253.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444412.1
GO:0004635 - phosphoribosyl-AMP cyclohydrolase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011281255.1
COORDINATES: similar to AA sequence:RefSeq:WP_011281256.1
GO:0015628 - protein secretion by the type II secretion system [Evidence IEA]; GO:0015031 - protein transport [Evidence IEA]
Sec-independent protein translocase protein TatB
COORDINATES: similar to AA sequence:RefSeq:WP_010197884.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514613.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444416.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514615.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514616.1
MutT removes an oxidatively damaged form of guanine from DNA . Other family members hydrolyse diverse nucleoside diphosphate derivatives (including ADP-ribose, GDP- mannose, TDP-glucose, NADH, UDP-sugars, dNTP and NTP).
COORDINATES: similar to AA sequence:RefSeq:WP_011281262.1
Catalyzes the reversible oxidation of ethanol to acetaldehyde with the concomitant reduction of NAD
COORDINATES: similar to AA sequence:RefSeq:WP_007394870.1
COORDINATES: similar to AA sequence:RefSeq:WP_007394869.1
COORDINATES: similar to AA sequence:RefSeq:WP_011281265.1
GO:0008961 - phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity [Evidence IEA]
GO:0009249 - protein lipoylation [Evidence IEA]
prolipoprotein diacylglyceryl transferase
COORDINATES: similar to AA sequence:RefSeq:WP_020444421.1
GO:0004799 - thymidylate synthase activity [Evidence IEA]
GO:0006231 - dTMP biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020444422.1
This family consists of the DNA repair enzyme UvrC, an ABC excinuclease subunit which interacts with the UvrA/UvrB complex to excise UV-damaged nucleotide segments.
COORDINATES: similar to AA sequence:RefSeq:WP_041753276.1
GO:0009381 - excinuclease ABC activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020444424.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514625.1
COORDINATES: similar to AA sequence:RefSeq:WP_011281271.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444427.1
GO:0052906 - tRNA (guanine(37)-N(1))-methyltransferase activity [Evidence IEA]
tRNA (guanosine(37)-N1)-methyltransferase TrmD
COORDINATES: similar to AA sequence:RefSeq:WP_011514628.1
Essential for efficient processing of 16S rRNA; Essential for efficient processing of 16S rRNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_011281274.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514629.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444431.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514631.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444433.1
GO:0046933 - proton-transporting ATP synthase activity, rotational mechanism [Evidence IEA]
GO:0015986 - proton motive force-driven ATP synthesis [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011281279.1
GO:0000275 - mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1) [Evidence IEA]; GO:0045262 - plasma membrane proton-transporting ATP synthase complex, catalytic core F(1) [Evidence IEA]; GO:0045261 - proton-transporting ATP synthase complex, catalytic core F(1) [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011281280.1
GO:0045261 - proton-transporting ATP synthase complex, catalytic core F(1) [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:YP_004997344.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514636.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514637.1
COORDINATES: similar to AA sequence:RefSeq:WP_010197960.1
COORDINATES: similar to AA sequence:RefSeq:WP_011281284.1
GO:0045263 - proton-transporting ATP synthase complex, coupling factor F(o) [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020444435.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514640.1
GO:0046872 - metal ion binding [Evidence IEA]
zinc ABC transporter substrate-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_011514641.1
COORDINATES: similar to AA sequence:RefSeq:WP_011281288.1
metal ABC transporter ATP-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_011514643.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444439.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514645.1
GO:0019899 - enzyme binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011281292.1
GO:0004812 - aminoacyl-tRNA ligase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020444441.1
putative peptidoglycan glycosyltransferase FtsW
COORDINATES: similar to AA sequence:RefSeq:WP_011281294.1
GO:0008764 - UDP-N-acetylmuramoylalanine-D-glutamate ligase activity [Evidence IEA]
UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase
COORDINATES: similar to AA sequence:RefSeq:WP_011514649.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444443.1
Nitrogen metabolism regulation, Glutamine biosynthesis
COORDINATES: similar to AA sequence:RefSeq:YP_004997399.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514652.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514653.1
COORDINATES: similar to AA sequence:RefSeq:WP_011281300.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444446.1
GO:0016787 - hydrolase activity [Evidence IEA]; GO:0046872 - metal ion binding [Evidence IEA]; GO:0003676 - nucleic acid binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011514677.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444459.1
GO:0008808 - cardiolipin synthase activity [Evidence IEA]
GO:0032049 - cardiolipin biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010198005.1
COORDINATES: similar to AA sequence:RefSeq:WP_011959433.1
GO:0008963 - phospho-N-acetylmuramoyl-pentapeptide-transferase activity [Evidence IEA]
phospho-N-acetylmuramoyl-pentapeptide- transferase
COORDINATES: similar to AA sequence:RefSeq:WP_020444462.1
GO:0047480 - UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity [Evidence IEA]
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase
COORDINATES: similar to AA sequence:RefSeq:WP_020444463.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0016874 - ligase activity [Evidence IEA]
GO:0009058 - biosynthetic process [Evidence IEA]; GO:0051301 - cell division [Evidence IEA]; GO:0008360 - regulation of cell shape [Evidence IEA]
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase
COORDINATES: similar to AA sequence:RefSeq:WP_011514683.1
COORDINATES: similar to AA sequence:RefSeq:WP_010200544.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514685.1
GO:0016434 - rRNA (cytosine) methyltransferase activity [Evidence IEA]
16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH
COORDINATES: similar to AA sequence:RefSeq:WP_011281311.1
GO:0009332 - glutamate-tRNA ligase complex [Evidence IEA]
GO:0004818 - glutamate-tRNA ligase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010200541.1
COORDINATES: similar to AA sequence:RefSeq:WP_011281313.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514689.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514690.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444473.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514692.1
Catalyses the removal of the ammonia group from glutamine and then to transfer this group to a substrate to form a new carbon-nitrogen group.
COORDINATES: similar to AA sequence:RefSeq:WP_011514693.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444476.1
COORDINATES: similar to AA sequence:RefSeq:WP_010200528.1
GO:0004413 - homoserine kinase activity [Evidence IEA]
GO:0009088 - threonine biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_017395071.1
GO:0000107 - imidazoleglycerol-phosphate synthase activity [Evidence IEA]
imidazole glycerol phosphate synthase subunit HisF
COORDINATES: similar to AA sequence:RefSeq:WP_011281323.1
GO:0009349 - riboflavin synthase complex [Evidence IEA]
GO:0000906 - 6,7-dimethyl-8-ribityllumazine synthase activity [Evidence IEA]
regulation of rRNA biosynthesis by transcriptional antitermination.
COORDINATES: similar to AA sequence:RefSeq:WP_011281324.1
transcription antitermination factor NusB
COORDINATES: similar to AA sequence:RefSeq:WP_011514699.1
GO:0009030 - thiamine-phosphate kinase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011514700.1
COORDINATES: similar to AA sequence:RefSeq:WP_011281327.1
GO:0019134 - glucosamine-1-phosphate N-acetyltransferase activity [Evidence IEA]; GO:0003977 - UDP-N-acetylglucosamine diphosphorylase activity [Evidence IEA]
GO:0009103 - lipopolysaccharide biosynthetic process [Evidence IEA]; GO:0009252 - peptidoglycan biosynthetic process [Evidence IEA]
bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU
COORDINATES: similar to AA sequence:RefSeq:WP_000334171.1
GO:0004360 - glutamine-fructose-6-phosphate transaminase (isomerizing) activity [Evidence IEA]
GO:0006040 - amino sugar metabolic process [Evidence IEA]; GO:0009252 - peptidoglycan biosynthetic process [Evidence IEA]
glutamine--fructose-6-phosphate transaminase (isomerizing)
COORDINATES: similar to AA sequence:RefSeq:WP_076611469.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444589.1
cytochrome b/b6 domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_020444568.1
COORDINATES: similar to AA sequence:RefSeq:WP_011959972.1
COORDINATES: similar to AA sequence:RefSeq:WP_011959973.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444569.1
involved in thiamin (vitamin B1) synthesis
COORDINATES: similar to AA sequence:RefSeq:WP_011959975.1
COORDINATES: similar to AA sequence:RefSeq:WP_011959976.1
COORDINATES: similar to AA sequence:RefSeq:WP_011281336.1
COORDINATES: similar to AA sequence:RefSeq:WP_011961565.1
COORDINATES: similar to AA sequence:RefSeq:WP_010200482.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514707.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0003678 - DNA helicase activity [Evidence IEA]; GO:0003676 - nucleic acid binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011514708.1
patatin-like phospholipase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_011514709.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514710.1
GO:0004042 - acetyl-CoA:L-glutamate N-acetyltransferase activity [Evidence IEA]
Involved in protein folding:accelerates protein folding by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
COORDINATES: similar to AA sequence:RefSeq:WP_020444500.1
FKBP-type peptidyl-prolyl cis-trans isomerase
COORDINATES: similar to AA sequence:RefSeq:WP_020444501.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444503.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444504.1
COORDINATES: similar to AA sequence:RefSeq:WP_011281347.1
COORDINATES: similar to AA sequence:RefSeq:WP_010201288.1
COORDINATES: similar to AA sequence:RefSeq:WP_011281349.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444510.1
GO:0004829 - threonine-tRNA ligase activity [Evidence IEA]
GO:0006435 - threonyl-tRNA aminoacylation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011281352.1
COORDINATES: similar to AA sequence:RefSeq:WP_010197321.1
involved in the degradation of mRNA, and consequently have strong pleiotropic effects that may be difficult to disentangle.
COORDINATES: similar to AA sequence:RefSeq:WP_020444512.1
GO:0008997 - ribonuclease R activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004992205.1
COORDINATES: similar to AA sequence:RefSeq:WP_011281356.1
GO:0003949 - 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase activity [Evidence IEA]
1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase
COORDINATES: similar to AA sequence:RefSeq:WP_003657766.1
GO:0016655 - oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [Evidence IEA]
GO:0006814 - sodium ion transport [Evidence IEA]
Na(+)-translocating NADH-quinone reductase subunit A
COORDINATES: similar to AA sequence:RefSeq:WP_011514726.1
GO:0010181 - FMN binding [Evidence IEA]; GO:0016655 - oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [Evidence IEA]
GO:0022904 - respiratory electron transport chain [Evidence IEA]; GO:0055085 - transmembrane transport [Evidence IEA]
NADH:ubiquinone reductase (Na(+)-transporting) subunit B
COORDINATES: similar to AA sequence:RefSeq:WP_011281359.1
Na(+)-translocating NADH-quinone reductase subunit C
COORDINATES: similar to AA sequence:RefSeq:WP_003657762.1
NADH:ubiquinone reductase (Na(+)-transporting) subunit D
COORDINATES: similar to AA sequence:RefSeq:WP_003657760.1
NADH:ubiquinone reductase (Na(+)-transporting) subunit E
COORDINATES: similar to AA sequence:RefSeq:WP_013108126.1
NADH:ubiquinone reductase (Na(+)-transporting) subunit F
COORDINATES: similar to AA sequence:RefSeq:WP_011514731.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514732.1
COORDINATES: similar to AA sequence:RefSeq:WP_019673786.1
catalytic activity:lipase,arylesterase,thermolabile hemolysin,phospholipase (AdRab-B),anter-specific proline-rich protein.
COORDINATES: similar to AA sequence:RefSeq:WP_020444519.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514735.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444521.1
COORDINATES: similar to AA sequence:RefSeq:WP_010200469.1
COORDINATES: similar to AA sequence:RefSeq:WP_019673787.1
COORDINATES: similar to AA sequence:RefSeq:WP_010197273.1
COORDINATES: similar to AA sequence:RefSeq:WP_011281373.1
GO:0016884 - carbon-nitrogen ligase activity, with glutamine as amido-N-donor [Evidence IEA]; GO:0000107 - imidazoleglycerol-phosphate synthase activity [Evidence IEA]
imidazole glycerol phosphate synthase subunit HisH
COORDINATES: similar to AA sequence:RefSeq:WP_010980958.1
GO:0004424 - imidazoleglycerol-phosphate dehydratase activity [Evidence IEA]
imidazoleglycerol-phosphate dehydratase HisB
COORDINATES: similar to AA sequence:RefSeq:WP_010197267.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444530.1
COORDINATES: similar to AA sequence:RefSeq:WP_011281377.1
GO:0008967 - phosphoglycolate phosphatase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011514745.1
YifB family Mg chelatase-like AAA ATPase
COORDINATES: similar to AA sequence:RefSeq:WP_020444534.1
oxygen-independent coproporphyrinogen III oxidase
COORDINATES: similar to AA sequence:RefSeq:WP_003660406.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444537.1
COORDINATES: similar to AA sequence:RefSeq:WP_003671363.1
COORDINATES: similar to AA sequence:RefSeq:WP_011281383.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444539.1
Ability to bind unfolded protein substrates in an ATP-dependent manner
COORDINATES: similar to AA sequence:RefSeq:YP_004996671.1
In prokaryotes the grpE protein stimulates, jointly with dnaJ, the ATPase activity of the dnaK chaperone. It seems to accelerate the release of ADP from dnaK thus allowing dnaK to recycle more efficiently.
COORDINATES: similar to AA sequence:RefSeq:WP_011514755.1
GO:0000774 - adenyl-nucleotide exchange factor activity [Evidence IEA]; GO:0051087 - chaperone binding [Evidence IEA]; GO:0042803 - protein homodimerization activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011514760.1
involved in transformation with exogenous DNA
COORDINATES: similar to AA sequence:RefSeq:WP_011514761.1
GO:0009294 - DNA-mediated transformation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_010197181.1
Threonine biosynthesis, Vitamin B6 metabolism
COORDINATES: similar to AA sequence:RefSeq:WP_020444549.1
GO:0004795 - threonine synthase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020444550.1
COORDINATES: similar to AA sequence:RefSeq:WP_011514765.1
GO:0004479 - methionyl-tRNA formyltransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_009508412.1
COORDINATES: similar to AA sequence:RefSeq:WP_020444554.1
GO:0008703 - 5-amino-6-(5-phosphoribosylamino)uracil reductase activity [Evidence IEA]; GO:0008835 - diaminohydroxyphosphoribosylaminopyrimidine deaminase activity [Evidence IEA]
bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD
COORDINATES: similar to AA sequence:RefSeq:WP_020444555.1
GO:0140110 - transcription regulator activity [Evidence IEA]
Involved in tRNA modification to create 5-methylaminomethyl-2-thiouridine in the wobble position of some tRNAs
COORDINATES: similar to AA sequence:RefSeq:WP_011281396.1
GO:0005525 - GTP binding [Evidence IEA]; GO:0003924 - GTPase activity [Evidence IEA]; GO:0005515 - protein binding [Evidence IEA]
tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE
COORDINATES: similar to AA sequence:RefSeq:WP_011281397.1
GO:0032977 - membrane insertase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_011281398.1
membrane protein insertion efficiency factor YidD
A site specific endonuclease that generates mature tRNAs by cleaving-off the leader sequences at their 5'ends.
COORDINATES: similar to AA sequence:RefSeq:WP_011281399.1
GO:0004526 - ribonuclease P activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_000831329.1