Leptospira kobayashii strain E30 chromosome 2, complete sequence.
Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae; Leptospira.
Complete genome sequence of Leptospira kobayashii strain E30
Submitted (24-AUG-2021) Contact:Ryo Nakao Faculty of Veterinary, Medicine Hokkaido University, Laboratory of Parasitology; N18 W9, Kitaku, Sapporo, Hokkaido 060-0818, Japan URL :https://www.vetmed.hokudai.ac.jp/organization/parasitol/en/ index.html
REFSEQ INFORMATION: The reference sequence is identical to\nAP025029.1.\nAnnotated by DFAST https://dfast.ddbj.nig.ac.jp/\n\nThe annotation was added by the NCBI Prokaryotic Genome Annotation\nPipeline (PGAP). Information about PGAP can be found here:\nhttps://www.ncbi.nlm.nih.gov/genome/annotation_prok/\n\n##Genome-Assembly-Data-START##\nAssembly Method :: Unicycler v. 0.4.7\nGenome Coverage :: 398x\nSequencing Technology :: Illumina MiSeq; GridION\n##Genome-Assembly-Data-END##\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: NCBI RefSeq\nAnnotation Date :: 04/13/2023 05:47:09\nAnnotation Pipeline :: NCBI Prokaryotic Genome\n Annotation Pipeline (PGAP)\nAnnotation Method :: Best-placed reference protein\n set; GeneMarkS-2+\nAnnotation Software revision :: 6.5\nFeatures Annotated :: Gene; CDS; rRNA; tRNA; ncRNA\nGenes (total) :: 3,948\nCDSs (total) :: 3,905\nGenes (coding) :: 3,888\nCDSs (with protein) :: 3,888\nGenes (RNA) :: 43\nrRNAs :: 2, 2, 2 (5S, 16S, 23S)\ncomplete rRNAs :: 2, 2, 2 (5S, 16S, 23S)\ntRNAs :: 35\nncRNAs :: 2\nPseudo Genes (total) :: 17\nCDSs (without protein) :: 17\nPseudo Genes (ambiguous residues) :: 0 of 17\nPseudo Genes (frameshifted) :: 1 of 17\nPseudo Genes (incomplete) :: 15 of 17\nPseudo Genes (internal stop) :: 1 of 17\n##Genome-Annotation-Data-END##\nCOMPLETENESS: full length.
COORDINATES: similar to AA sequence:RefSeq:WP_020762606.1
Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_020777220.1
COORDINATES: similar to AA sequence:RefSeq:WP_000290139.1
GO:0033743 - peptide-methionine (R)-S-oxide reductase activity [Evidence IEA]
GO:0030091 - protein repair [Evidence IEA]; GO:0006979 - response to oxidative stress [Evidence IEA]
peptide-methionine (R)-S-oxide reductase MsrB
COORDINATES: similar to AA sequence:RefSeq:WP_015682967.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0016887 - ATP hydrolysis activity [Evidence IEA]; GO:0004386 - helicase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004779773.1
GO:1904047 - S-adenosyl-L-methionine binding [Evidence IEA]; GO:0008757 - S-adenosylmethionine-dependent methyltransferase activity [Evidence IEA]
cyclopropane-fatty-acyl-phospholipid synthase family protein
COORDINATES: protein motif:HMM:NF018649.2
incomplete; partial in the middle of a contig; missing C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology.
COORDINATES: similar to AA sequence:RefSeq:WP_008588746.1
SDR family NAD(P)-dependent oxidoreductase
COORDINATES: similar to AA sequence:RefSeq:WP_004788099.1
COORDINATES: ab initio prediction:GeneMarkS-2+
Derived by automated computational analysis using gene prediction method: GeneMarkS-2+.
COORDINATES: similar to AA sequence:RefSeq:WP_020777178.1
COORDINATES: similar to AA sequence:RefSeq:WP_016544031.1
GO:0004601 - peroxidase activity [Evidence IEA]
GO:0006979 - response to oxidative stress [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004788133.1
COORDINATES: similar to AA sequence:RefSeq:WP_015683010.1
COORDINATES: similar to AA sequence:RefSeq:WP_002979510.1
COORDINATES: similar to AA sequence:RefSeq:WP_004757601.1
GO:0000160 - phosphorelay signal transduction system [Evidence IEA]; GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_002979579.1
COORDINATES: similar to AA sequence:RefSeq:WP_002975687.1
COORDINATES: similar to AA sequence:RefSeq:WP_015679383.1
COORDINATES: similar to AA sequence:RefSeq:WP_015677527.1
GO:0008234 - cysteine-type peptidase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_015679452.1
GO:0010038 - response to metal ion [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_002979501.1
GO:0015663 - nicotinamide mononucleotide transmembrane transporter activity [Evidence IEA]
GO:0015890 - nicotinamide mononucleotide transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_002989259.1
COORDINATES: protein motif:HMM:NF024777.2
LamG-like jellyroll fold domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_004788079.1
GO:0008168 - methyltransferase activity [Evidence IEA]; GO:1904047 - S-adenosyl-L-methionine binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020777226.1
GO:0003994 - aconitate hydratase activity [Evidence IEA]
GO:0006099 - tricarboxylic acid cycle [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004787994.1
COORDINATES: similar to AA sequence:RefSeq:WP_002975672.1
GO:0016853 - isomerase activity [Evidence IEA]; GO:0016740 - transferase activity [Evidence IEA]
tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA
COORDINATES: similar to AA sequence:RefSeq:WP_015682818.1
GO:0016757 - glycosyltransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008589109.1
COORDINATES: similar to AA sequence:RefSeq:WP_012476725.1
COORDINATES: similar to AA sequence:RefSeq:WP_020777094.1
COORDINATES: similar to AA sequence:RefSeq:WP_002179700.1
GO:0016746 - acyltransferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_002975798.1
COORDINATES: similar to AA sequence:RefSeq:WP_004426036.1
COORDINATES: similar to AA sequence:RefSeq:WP_020776195.1
TonB-dependent receptor plug domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_015683009.1
COORDINATES: similar to AA sequence:RefSeq:WP_012476735.1
GO:0007165 - signal transduction [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_016543618.1
COORDINATES: similar to AA sequence:RefSeq:WP_012476742.1
COORDINATES: similar to AA sequence:RefSeq:WP_015682999.1
GO:0004743 - pyruvate kinase activity [Evidence IEA]
GO:0006096 - glycolytic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_002979508.1
COORDINATES: similar to AA sequence:RefSeq:WP_020777158.1
GO:0004073 - aspartate-semialdehyde dehydrogenase activity [Evidence IEA]
GO:0009089 - lysine biosynthetic process via diaminopimelate [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_002749396.1
COORDINATES: similar to AA sequence:RefSeq:WP_020777142.1
COORDINATES: similar to AA sequence:RefSeq:WP_010572574.1
COORDINATES: similar to AA sequence:RefSeq:WP_012476748.1
COORDINATES: similar to AA sequence:RefSeq:WP_020763258.1
COORDINATES: similar to AA sequence:RefSeq:WP_012476751.1
GO:0043565 - sequence-specific DNA binding [Evidence IEA]
helix-turn-helix domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_000637633.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0016887 - ATP hydrolysis activity [Evidence IEA]
GO:0007059 - chromosome segregation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_012476479.1
GO:0007059 - chromosome segregation [Evidence IEA]; GO:0000910 - cytokinesis [Evidence IEA]
ParB/RepB/Spo0J family partition protein
COORDINATES: similar to AA sequence:RefSeq:WP_012476480.1
COORDINATES: similar to AA sequence:RefSeq:WP_002975734.1
COORDINATES: similar to AA sequence:RefSeq:WP_004788005.1
COORDINATES: similar to AA sequence:RefSeq:WP_002975668.1
COORDINATES: similar to AA sequence:RefSeq:WP_020777251.1
COORDINATES: similar to AA sequence:RefSeq:WP_015679391.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0000155 - phosphorelay sensor kinase activity [Evidence IEA]; GO:0004673 - protein histidine kinase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_002991623.1
GO:0005524 - ATP binding [Evidence IEA]; GO:0016887 - ATP hydrolysis activity [Evidence IEA]; GO:0051082 - unfolded protein binding [Evidence IEA]
GO:0006457 - protein folding [Evidence IEA]
COORDINATES: protein motif:HMM:NF024973.2
COORDINATES: protein motif:HMM:NF012321.2
COORDINATES: similar to AA sequence:RefSeq:WP_012476489.1
COORDINATES: protein motif:HMM:NF024909.2
COORDINATES: similar to AA sequence:RefSeq:WP_002991636.1
COORDINATES: similar to AA sequence:RefSeq:WP_002991577.1
COORDINATES: similar to AA sequence:RefSeq:WP_004788077.1
GO:0047617 - acyl-CoA hydrolase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_002975631.1
GO:0016787 - hydrolase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020777129.1
COORDINATES: similar to AA sequence:RefSeq:WP_010409947.1
GO:0004725 - protein tyrosine phosphatase activity [Evidence IEA]
GO:0006470 - protein dephosphorylation [Evidence IEA]
low molecular weight protein-tyrosine-phosphatase
COORDINATES: protein motif:HMM:NF013980.2
GO:0046872 - metal ion binding [Evidence IEA]; GO:0008237 - metallopeptidase activity [Evidence IEA]
SprT family zinc-dependent metalloprotease
COORDINATES: similar to AA sequence:RefSeq:WP_012476501.1
COORDINATES: similar to AA sequence:RefSeq:WP_004788215.1
COORDINATES: similar to AA sequence:RefSeq:WP_016545481.1
COORDINATES: similar to AA sequence:RefSeq:WP_020777081.1
COORDINATES: similar to AA sequence:RefSeq:WP_020777107.1
GO:0010181 - FMN binding [Evidence IEA]; GO:0016491 - oxidoreductase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_015679302.1
GO:0016747 - acyltransferase activity, transferring groups other than amino-acyl groups [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_008589074.1
GO:0030551 - cyclic nucleotide binding [Evidence IEA]
cyclic nucleotide-binding domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_002975686.1
COORDINATES: similar to AA sequence:RefSeq:WP_012476816.1
COORDINATES: similar to AA sequence:RefSeq:WP_012476510.1
COORDINATES: similar to AA sequence:RefSeq:WP_002975681.1
COORDINATES: similar to AA sequence:RefSeq:WP_015682906.1
COORDINATES: similar to AA sequence:RefSeq:WP_002975595.1
GO:0030261 - chromosome condensation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_012476514.1
GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; GO:0016491 - oxidoreductase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020777122.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]
GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]
TetR/AcrR family transcriptional regulator
COORDINATES: similar to AA sequence:RefSeq:WP_012476516.1
diacylglycerol kinase family lipid kinase
COORDINATES: similar to AA sequence:RefSeq:WP_016757359.1
GO:0071949 - FAD binding [Evidence IEA]; GO:0016491 - oxidoreductase activity [Evidence IEA]
glycerol-3-phosphate dehydrogenase/oxidase
COORDINATES: similar to AA sequence:RefSeq:WP_004788084.1
COORDINATES: similar to AA sequence:RefSeq:WP_004788120.1
COORDINATES: protein motif:HMM:NF018884.2
GO:0016791 - phosphatase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004788020.1
COORDINATES: similar to AA sequence:RefSeq:WP_004787888.1
COORDINATES: protein motif:HMM:TIGR00229.1
HAMP domain-containing sensor histidine kinase
COORDINATES: protein motif:HMM:NF012301.2
GO:0000160 - phosphorelay signal transduction system [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_002991619.1
GO:0016798 - hydrolase activity, acting on glycosyl bonds [Evidence IEA]
lytic transglycosylase domain-containing protein
COORDINATES: protein motif:HMM:NF015423.2
GO:0016020 - membrane [Evidence IEA]; GO:0005886 - plasma membrane [Evidence IEA]
trimeric intracellular cation channel family protein
COORDINATES: protein motif:HMM:NF024109.2
COORDINATES: similar to AA sequence:RefSeq:WP_002974442.1
patatin-like phospholipase family protein
COORDINATES: protein motif:HMM:NF013073.2
COORDINATES: similar to AA sequence:RefSeq:WP_002975751.1
Spy/CpxP family protein refolding chaperone
COORDINATES: similar to AA sequence:RefSeq:WP_015682865.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]; GO:0016987 - sigma factor activity [Evidence IEA]
GO:0006352 - DNA-templated transcription initiation [Evidence IEA]; GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]
sigma-70 family RNA polymerase sigma factor
COORDINATES: similar to AA sequence:RefSeq:WP_015679215.1
COORDINATES: similar to AA sequence:RefSeq:WP_002772979.1
COORDINATES: similar to AA sequence:RefSeq:WP_015679246.1
GO:0003824 - catalytic activity [Evidence IEA]; GO:0015930 - glutamate synthase activity [Evidence IEA]; GO:0016491 - oxidoreductase activity [Evidence IEA]
GO:0006537 - glutamate biosynthetic process [Evidence IEA]; GO:0006807 - nitrogen compound metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_012476545.1
COORDINATES: protein motif:HMM:NF024583.2
COORDINATES: similar to AA sequence:RefSeq:WP_002975709.1
COORDINATES: similar to AA sequence:RefSeq:WP_015682830.1
COORDINATES: similar to AA sequence:RefSeq:WP_000956229.1
COORDINATES: similar to AA sequence:RefSeq:WP_002980688.1
COORDINATES: similar to AA sequence:RefSeq:WP_004788025.1
four-helix bundle copper-binding protein
COORDINATES: similar to AA sequence:RefSeq:WP_020777217.1
COORDINATES: similar to AA sequence:RefSeq:WP_015680831.1
GO:0009975 - cyclase activity [Evidence IEA]; GO:0046872 - metal ion binding [Evidence IEA]; GO:0016849 - phosphorus-oxygen lyase activity [Evidence IEA]; GO:0032555 - purine ribonucleotide binding [Evidence IEA]
adenylate/guanylate cyclase domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_002990465.1
GO:0004222 - metalloendopeptidase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_002975897.1
outer membrane protein transport protein
COORDINATES: similar to AA sequence:RefSeq:WP_004788150.1
UTP--glucose-1-phosphate uridylyltransferase
COORDINATES: similar to AA sequence:RefSeq:WP_012476557.1
COORDINATES: similar to AA sequence:RefSeq:WP_015679349.1
COORDINATES: similar to AA sequence:RefSeq:WP_015682853.1
GO:0016790 - thiolester hydrolase activity [Evidence IEA]
COORDINATES: protein motif:HMM:NF012340.2
COORDINATES: similar to AA sequence:RefSeq:WP_015679377.1
GO:0031992 - energy transducer activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_003010252.1
GO:0022857 - transmembrane transporter activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004788069.1
GO:0005886 - plasma membrane [Evidence IEA]
GO:0015031 - protein transport [Evidence IEA]
MotA/TolQ/ExbB proton channel family protein
COORDINATES: similar to AA sequence:RefSeq:WP_004788219.1
COORDINATES: similar to AA sequence:RefSeq:WP_002975752.1
COORDINATES: similar to AA sequence:RefSeq:WP_015682956.1
GO:0035438 - cyclic-di-GMP binding [Evidence IEA]
COORDINATES: protein motif:HMM:NF016424.2
COORDINATES: protein motif:HMM:NF013955.2
COORDINATES: similar to AA sequence:RefSeq:WP_012476567.1
GO:0005525 - GTP binding [Evidence IEA]; GO:0003924 - GTPase activity [Evidence IEA]
methylmalonyl Co-A mutase-associated GTPase MeaB
COORDINATES: similar to AA sequence:RefSeq:WP_002775512.1
GO:0031419 - cobalamin binding [Evidence IEA]; GO:0046872 - metal ion binding [Evidence IEA]; GO:0004494 - methylmalonyl-CoA mutase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_002980759.1
GO:0031419 - cobalamin binding [Evidence IEA]; GO:0016866 - intramolecular transferase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004788068.1
COORDINATES: similar to AA sequence:RefSeq:WP_015683048.1
COORDINATES: similar to AA sequence:RefSeq:WP_002980630.1
COORDINATES: similar to AA sequence:RefSeq:WP_004788278.1
COORDINATES: similar to AA sequence:RefSeq:WP_015682871.1
GO:0005215 - transporter activity [Evidence IEA]
GO:0055085 - transmembrane transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004788270.1
COORDINATES: similar to AA sequence:RefSeq:WP_000992621.1
GO:0004014 - adenosylmethionine decarboxylase activity [Evidence IEA]
GO:0008295 - spermidine biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_002733373.1
COORDINATES: protein motif:HMM:NF014624.2
GO:0003677 - DNA binding [Evidence IEA]; GO:0046872 - metal ion binding [Evidence IEA]
COORDINATES: protein motif:HMM:TIGR01297.1
GO:0008324 - monoatomic cation transmembrane transporter activity [Evidence IEA]
cation diffusion facilitator family transporter
COORDINATES: similar to AA sequence:RefSeq:WP_002745077.1
COORDINATES: protein motif:HMM:NF019404.2
COORDINATES: similar to AA sequence:RefSeq:WP_017809925.1
COORDINATES: similar to AA sequence:RefSeq:WP_002975600.1
COORDINATES: similar to AA sequence:RefSeq:WP_015683002.1
GO:0004590 - orotidine-5'-phosphate decarboxylase activity [Evidence IEA]
GO:0009220 - pyrimidine ribonucleotide biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_015679354.1
GO:0016491 - oxidoreductase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_012476828.1
COORDINATES: similar to AA sequence:RefSeq:WP_002980649.1
COORDINATES: similar to AA sequence:RefSeq:WP_015680585.1
COORDINATES: protein motif:HMM:NF038065.1
COORDINATES: similar to AA sequence:RefSeq:WP_002980622.1
COORDINATES: similar to AA sequence:RefSeq:WP_015682885.1
COORDINATES: similar to AA sequence:RefSeq:WP_002980783.1
COORDINATES: similar to AA sequence:RefSeq:WP_015682984.1
COORDINATES: similar to AA sequence:RefSeq:WP_002980730.1
GO:0016779 - nucleotidyltransferase activity [Evidence IEA]
GO:0009058 - biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_015679297.1
GO:0003824 - catalytic activity [Evidence IEA]
NAD-dependent epimerase/dehydratase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_010576028.1
COORDINATES: similar to AA sequence:RefSeq:WP_012476832.1
COORDINATES: similar to AA sequence:RefSeq:WP_012476597.1
COORDINATES: similar to AA sequence:RefSeq:WP_015679341.1
COORDINATES: similar to AA sequence:RefSeq:WP_012476599.1
COORDINATES: similar to AA sequence:RefSeq:WP_002980804.1
COORDINATES: similar to AA sequence:RefSeq:WP_004425963.1
GO:0003999 - adenine phosphoribosyltransferase activity [Evidence IEA]
GO:0006168 - adenine salvage [Evidence IEA]; GO:0009116 - nucleoside metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_012476602.1
COORDINATES: similar to AA sequence:RefSeq:WP_012476603.1
COORDINATES: similar to AA sequence:RefSeq:WP_012476604.1
ClpXP protease specificity-enhancing factor SspB
COORDINATES: similar to AA sequence:RefSeq:WP_012476836.1
GO:0000271 - polysaccharide biosynthetic process [Evidence IEA]
nucleoside-diphosphate sugar epimerase/dehydratase
COORDINATES: similar to AA sequence:RefSeq:WP_015682900.1
COORDINATES: protein motif:HMM:TIGR01970.1
GO:0004386 - helicase activity [Evidence IEA]
GO:0006139 - nucleobase-containing compound metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004787996.1
helix-turn-helix transcriptional regulator
COORDINATES: similar to AA sequence:RefSeq:WP_005824469.1
HipA N-terminal domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_004788135.1
COORDINATES: protein motif:HMM:NF020177.2
COORDINATES: similar to AA sequence:RefSeq:WP_004502699.1
GO:0015074 - DNA integration [Evidence IEA]
integrase core domain-containing protein
COORDINATES: protein motif:HMM:NF014625.2
GO:0019213 - deacetylase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_002999017.1
COORDINATES: protein motif:HMM:NF016648.2
COORDINATES: similar to AA sequence:RefSeq:WP_020777109.1
GO:0003677 - DNA binding [Evidence IEA]; GO:0016987 - sigma factor activity [Evidence IEA]
GO:0006352 - DNA-templated transcription initiation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_015679353.1
GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]; GO:0003957 - NAD(P)+ transhydrogenase (B-specific) activity [Evidence IEA]
GO:0045454 - cell redox homeostasis [Evidence IEA]
COORDINATES: protein motif:HMM:NF012621.2
GO:0046872 - metal ion binding [Evidence IEA]
heavy-metal-associated domain-containing protein
COORDINATES: similar to AA sequence:RefSeq:WP_002980675.1
GO:0008379 - thioredoxin peroxidase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004788023.1
COORDINATES: similar to AA sequence:RefSeq:WP_012476621.1
COORDINATES: similar to AA sequence:RefSeq:WP_002975711.1
COORDINATES: similar to AA sequence:RefSeq:WP_008595091.1
GO:0003684 - damaged DNA binding [Evidence IEA]; GO:0003887 - DNA-directed DNA polymerase activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020777199.1
COORDINATES: similar to AA sequence:RefSeq:WP_004787954.1
PAS domain-containing hybrid sensor histidine kinase/response regulator
COORDINATES: protein motif:HMM:NF014525.2
COORDINATES: similar to AA sequence:RefSeq:WP_012476627.1
GO:0015252 - proton channel activity [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_012476840.1
GO:0008168 - methyltransferase activity [Evidence IEA]
GO:0008299 - isoprenoid biosynthetic process [Evidence IEA]
ubiquinone/menaquinone biosynthesis methyltransferase
COORDINATES: protein motif:HMM:TIGR04456.1
COORDINATES: similar to AA sequence:RefSeq:WP_002975662.1
COORDINATES: protein motif:HMM:NF012711.2
class I adenylate-forming enzyme family protein
COORDINATES: protein motif:HMM:NF016800.2
COORDINATES: similar to AA sequence:RefSeq:WP_015679276.1
TraR/DksA family transcriptional regulator
COORDINATES: similar to AA sequence:RefSeq:WP_004459639.1
GO:0022625 - cytosolic large ribosomal subunit [Evidence IEA]; GO:0000315 - organellar large ribosomal subunit [Evidence IEA]
GO:0003735 - structural constituent of ribosome [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020777207.1
GO:0015293 - symporter activity [Evidence IEA]
bile acid:sodium symporter family protein
COORDINATES: similar to AA sequence:RefSeq:WP_004788234.1
aminotransferase class V-fold PLP-dependent enzyme
COORDINATES: similar to AA sequence:RefSeq:WP_004788041.1
GO:0008784 - alanine racemase activity [Evidence IEA]
GO:0009252 - peptidoglycan biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_020777182.1
COORDINATES: similar to AA sequence:RefSeq:WP_015682994.1
carbon-nitrogen hydrolase family protein
COORDINATES: similar to AA sequence:RefSeq:WP_004756398.1
GO:0003991 - acetylglutamate kinase activity [Evidence IEA]
GO:0006592 - ornithine biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_015682876.1
COORDINATES: similar to AA sequence:RefSeq:WP_015679243.1
COORDINATES: similar to AA sequence:RefSeq:WP_020777232.1
COORDINATES: similar to AA sequence:RefSeq:WP_015683023.1
COORDINATES: similar to AA sequence:RefSeq:WP_002980834.1
COORDINATES: similar to AA sequence:RefSeq:WP_002980698.1
GO:0031419 - cobalamin binding [Evidence IEA]; GO:0008705 - methionine synthase activity [Evidence IEA]; GO:0008270 - zinc ion binding [Evidence IEA]
GO:0009086 - methionine biosynthetic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_004788267.1
COORDINATES: similar to AA sequence:RefSeq:WP_012476655.1
GO:0004013 - adenosylhomocysteinase activity [Evidence IEA]
GO:0006730 - one-carbon metabolic process [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_002980853.1
GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]
metalloregulator ArsR/SmtB family transcription factor
COORDINATES: protein motif:HMM:NF022072.2
COORDINATES: similar to AA sequence:RefSeq:WP_004787938.1
COORDINATES: protein motif:HMM:NF012245.2
COORDINATES: similar to AA sequence:RefSeq:WP_012476658.1
COORDINATES: similar to AA sequence:RefSeq:WP_004487293.1
COORDINATES: similar to AA sequence:RefSeq:WP_002975590.1
COORDINATES: similar to AA sequence:RefSeq:WP_012476661.1
COORDINATES: similar to AA sequence:RefSeq:WP_015679392.1
COORDINATES: similar to AA sequence:RefSeq:WP_015679461.1
GO:0005515 - protein binding [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_015679393.1
GO:0015087 - cobalt ion transmembrane transporter activity [Evidence IEA]; GO:0015095 - magnesium ion transmembrane transporter activity [Evidence IEA]
GO:0006824 - cobalt ion transport [Evidence IEA]; GO:0015693 - magnesium ion transport [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_002975801.1
COORDINATES: similar to AA sequence:RefSeq:WP_004788221.1
COORDINATES: protein motif:HMM:NF012334.2
COORDINATES: similar to AA sequence:RefSeq:WP_012476670.1
GO:0016835 - carbon-oxygen lyase activity [Evidence IEA]
GO:0019509 - L-methionine salvage from methylthioadenosine [Evidence IEA]
methylthioribulose 1-phosphate dehydratase
COORDINATES: similar to AA sequence:RefSeq:WP_002733336.1
GO:0003746 - translation elongation factor activity [Evidence IEA]
GO:0006414 - translational elongation [Evidence IEA]
COORDINATES: similar to AA sequence:RefSeq:WP_015682915.1
COORDINATES: protein motif:HMM:NF019235.2