Sudan ebolavirus isolate Sudan virus/H.sapiens-tc/UGA/2000/Gulu-808892, complete genome.
Viruses; ssRNA viruses; ssRNA negative-strand viruses; Mononegavirales; Filoviridae; Ebolavirus.
Complete genome sequence of an Ebola virus (Sudan species) responsible for a 2000 outbreak of human disease in Uganda
Submitted (15-NOV-2004) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (20-AUG-2004) National Center for Infectious Diseases, Division of Viral and Rickettsial Diseases, Special Pathogens Branch, Centers for Disease Control & Prevention, 1600 Clifton Road N.E., Building 15, Room SB611, Mail-Stop G-14, Atlanta, GA 30333, USA
REVIEWED REFSEQ: This record has been curated by NCBI staff. The\nreference sequence was derived from AY729654.\nCOMPLETENESS: full length.
Sudan virus/H.sapiens-tc/UGA/2000/Gulu-808892
regulation of initiation of RNA replication
experimental evidence, no additional details recorded
RNA-dependent RNA polymerase cofactor; cofactor in polymerase complex; type I IFN antagonist
coalesce nucleocapsids and cell membranes in virion assembly (budding)
structural glycoprotein; processed by furin to yield GP1-GP2 heterodimer that forms membrane-anchored trimers (peplomers)
small non-structural secreted glycoprotein; forms dimers linked by disulfide bonds (parallel orientation); processed by furin to yield sGP and delta peptide; sGP
ssGP; second non-structural secreted glycoprotein; super small secreted glycoprotein; secreted in a monomeric form; one A residue is deleted or two additional A residues are inserted at the editing site during transcription of the GP gene
transcription editing site; polymerase slippage of 1 nucleotide (-1 direction) during transcription results in the addition of an extra adenosine and the translation of an altenate frame leading to expression of GP
synthesis of viral RNAs; transcriptional editing
translation may start at the 2nd methionine codon of the ORF