Trypanosoma brucei brucei TREU927 chromosome 1, complete sequence.
Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina; Trypanosomatida; Trypanosomatidae; Trypanosoma.
The DNA sequence of chromosome I of an African trypanosome: gene content, chromosome organisation, recombination and polymorphism
Submitted (10-APR-2018) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (27-JUN-2005) Hertz-Fowler C., The Wellcome Trust Sanger Institute Genome Campus, Hinxton, Cambridge CB10 1SA, UK
Submitted (20-SEP-2002) The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK
PROVISIONAL REFSEQ: This record has not yet been subject to final\nNCBI review. The reference sequence is identical to AL929603.\nThis sequence and annotation represents version 4 of Trypanosoma\nbrucei chromosome 1. For more information about this sequence or\nthe Trypanosoma projects at the Sanger Institute , see\nhttp://www.sanger.ac.uk/Projects/ T_brucei or the GeneDB database\n(http://www.genedb.org).\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: INSDC submitter\nAnnotation Status :: Full annotation\nAnnotation Pipeline :: Eukaryotic Annotation Propagation Pipeline\n##Genome-Annotation-Data-END##
inferred VSG 3' UTR, partim; TGATATATTTTAAC 14-mer derived from published consensus (Berberof et al. 1995; Majumder, Boothroyd and Weber, 1981); VSG 3'-UTR 14-mer
variant surface glycoprotein (VSG), putative
GPI-Anchor Signal predicted for Tb927.1.05 by DGPI v2.04 with cleavage site probability 2.4940002 near 503
Signal peptide predicted for Tb927.1.05 by SignalP 2.0 HMM (Signal peptide probabilty 0.961, signal anchor probability 0.000) with cleavage site probability 0.450 between residues 21 and 22
Signal peptide predicted for Tb927.1.10 by SignalP 2.0 HMM (Signal peptide probabilty 0.946, signal anchor probability 0.048) with cleavage site probability 0.199 between residues 22 and 23
1 probable transmembrane helix predicted for Tb927.1.10 by TMHMM2.0 at aa 7-29
Majority of WCS reads call C, One WCS read calls T; type 1 (single nucleotide substitutions)
Majority of WCS reads call C, One WCS read calls A; type 1 (single nucleotide substitutions)
putative VSG expression site promoter. bases 1-21 from correspond to promoter identified in entry EMBL:X67472; bases 7-26 correspond to VUE (PMID:9297697); bases 31-58 correspond to VDE (PMID:9297697)
86% id to VSG ES promoter downstream element (VDE); PMID:9297697
76% id to VSG ES promoter upstream element (VUE); PMID:9297697
Majority of WCS reads call G, One WCS read calls T; type 1 (single nucleotide substitutions)
Majority of WCS reads call A, One WCS read calls C; type 1 (single nucleotide substitutions)
Majority of WCS reads call G, One WCS read calls A; type 1 (single nucleotide substitutions)
Majority of WCS reads call T, One WCS read calls C; type 1 (single nucleotide substitutions)
Two WCS reads call C, Two WCS reads call T; type 1 (single nucleotide substitutions)
Majority of WCS reads call A, One WCS read calls G; type 1 (single nucleotide substitutions)
Majority of WCS reads call TGTTT, One WCS read calls TTTT; type 2 (single nucleotide insertions/deletions)
Two WCS reads call A, Two WCS reads call G; type 1 (single nucleotide substitutions)
Majority of WCS reads call C, One WCS read calls G; type 1 (single nucleotide substitutions)
Majority of genomic shotgun reads call A, One genomic shotgun read calls T; type 1 (single nucleotide substitutions)
Signal peptide predicted for Tb927.1.50 by SignalP 2.0 HMM (Signal peptide probabilty 0.997, signal anchor probability 0.000) with cleavage site probability 0.455 between residues 18 and 19
Majority of WCS reads call 7 T, One WCS read calls 6 T; type 2 (single nucleotide insertions/deletions)
Majority of WCS reads call T, Two WCS reads calls C; type 1 (single nucleotide substitutions)
Majority of WCS reads call C, Three WCS reads call A; type 1 (single nucleotide substitutions)
Majority of WCS reads call T, Two WCS reads call C; type 1 (single nucleotide substitutions)
Majority of WCS reads call TTTAAAATAAA;Two WCS read calls TTAAAGAAAAAA; type 8 (unclassified)
Majority of WCS reads call 11 A, Two WCS reads call 13 A; type 6 (insertion/deletion of 2 nucleotides)
Majority of WCS reads call CATATATATATATAAT;One WCS read calls CATATATATAACC; type 5 (insertion/deletion of more than 3 nucleotides in microsatellites)
Majority of WCS reads call C or G;One WCS read calls T or A; type 9 (single nucleotide substitutions)
Majority of WCS reads call 4 T, One WCS read calls 5 T; type 2 (single nucleotide insertions/deletions)
Majority of WCS reads call C, One WCS read calls G.; type 1 (single nucleotide substitutions)
Majority of WCS reads call T, One WCS read calls G; type 1 (single nucleotide substitutions)
Majority of genomic shotgun reads call A, One genomic shotgun read calls G; type 1 (single nucleotide substitutions)
retrotransposon hot spot (RHS) protein; retrotransposon hot spot protein 4 (RHS4)
RHS4 sequence at 3'-end of RHS5-RHS4 chimera
RHS5 sequence at 5'-end of RHS5-RHS4 chimera
Majority of WCS reads call T, One WCS read calls A; type 1 (single nucleotide substitutions)
retrotransposon hot spot protein (RHS, pseudogene), putative
RHS3 sequence at 3'-end of RHS1-RHS3 chimeric pseudogene
RHS1 sequence at 5'-end of RHS1-RHS3 chimeric pseudogene
One WCS read calls T, One WCS read calls C; type 1 (single nucleotide substitutions)
One WCS read calls A, One WCS read calls T; type 1 (single nucleotide substitutions)
One WCS read calls C, One WCS read calls T; type 1 (single nucleotide substitutions)
One WCS read calls A, One WCS read calls C; type 1 (single nucleotide substitutions)
Signal peptide predicted for Tb927.1.110 by SignalP 2.0 HMM (Signal peptide probabilty 0.658, signal anchor probability 0.015) with cleavage site probability 0.267 between residues 59 and 60
1 probable transmembrane helix predicted for Tb927.1.110 by TMHMM2.0 at aa 13-35
Majority of WCS reads call A, One WCS read calls C; type 1 (single nucleotide substitutions); silent mutation in Tb927.1.120
Majority of WCS reads call C, One WCS read calls G; type 1 (single nucleotide substitutions); mis-sense mutation at 827 in Tb927.1.120 G -> A
Majority of WCS reads call C, One WCS read calls T; type 1 (single nucleotide substitutions); silent mutation in Tb927.1.120
Majority of WCS reads call C, One WCS read calls T; type 1 (single nucleotide substitutions); mis-sense mutation at 814 in Tb927.1.120 R -> Q
Majority of WCS reads call C, One WCS read calls T; type 1 (single nucleotide substitutions); mis-sense mutation at 798 in Tb927.1.120 D -> N
Majority of WCS reads call G, One WCS read calls T; type 1 (single nucleotide substitutions); mis-sense mutation at 780 in Tb927.1.120 A -> D
Majority of WCS reads call A, One WCS read calls G; type 1 (single nucleotide substitutions); silent mutation in Tb927.1.120
Majority of WCS reads call C, One WCS read calls T; type 1 (single nucleotide substitutions); mis-sense mutation at 738 in Tb927.1.120 M -> I
retrotransposon hot spot (RHS) protein; retrotransposon hot spot protein 1 (RHS1)
Majority of WCS reads and TP3D18 call T, One WCS read calls G; type 1 (single nucleotide substitutions)
Majority of WCS,TPB12C6 and TP3D18 reads call T, One WCS read calls C; type 1 (single nucleotide substitutions)
Majority of WCS,TP3D18 and TPB12C6 reads call C, One WCS read calls T; type 1 (single nucleotide substitutions)
Majority of WCS,TP3D18 and TPB12C6 reads call A, One WCS read calls T; type 1 (single nucleotide substitutions)
RHS2 sequence at 3'-end of RHS1-RHS2 chimeric pseudogene
RHS1 sequence at 5'-end of RHS1-RHS2 chimeric pseudogene
Majority of WCS reads call 3 A, One WCS read calls 4 A; type 2 (single nucleotide insertions/deletions)
Majority of genomic shotgun reads call A, One genomic shotgun read calls C; type 1 (single nucleotide substitutions)
2 probable transmembrane helices predicted for Tb927.1.200 by TMHMM2.0 at aa 7-29 and 44-66
Majority of WCS reads and TP3D18 reads call C, One WCS read calls G; type 1 (single nucleotide substitutions)
inverted telomeric repeat hexamer CCCTAA
RHS2 sequence at 3'-end of RHS1-RHS2-ingi-RHS2 chimeric pseudogene
possible CDS (len=2003 aa) produced by in-frame insertion of ingi element into retrotransposon hot spot protein, RHS2j; part of RHS1-RHS2-ingi-RHS2 chimera, probably a pseudogene
Majority of WCS,TP3D18 and TPB12C6 reads call G, Two WCS reads call C; type 1 (single nucleotide substitutions)
Majority of WCS,TP3D18 and TPB12C6 reads call T, Two WCS reads call A; type 1 (single nucleotide substitutions)
5'-end of RHS1-RHS2-ingi-RHS2 chimeric pseudogene or may be 5'-end of expressed RHS1-RHS2-ingi protein 1 chimera
RHS2 sequence near 5'-end of RHS1-RHS2-ingi-RHS2 chimeric pseudogene
RHS1 sequence at 5'-end of RHS1-RHS2-ingi-RHS2 chimeric pseudogene
Majority of WCS and TPB12C6 reads call G, One WCS read calls A; type 1 (single nucleotide substitutions)
Majority of WCS,TP3D18, and TPB12C6 reads call T, One WCS read calls A; type 1 (single nucleotide substitutions)
Majority of WCS reads,TP3D18 and TPB12C6 reads call T, One WCS read calls A; type 1 (single nucleotide substitutions)
Majority of WCS reads,TP3D18 and TPB12C6 reads call G, One WCS read calls A; type 1 (single nucleotide substitutions)
Majority of WCS,TP3D18 and TPB12C6 reads call A, One WCS read calls C; type 1 (single nucleotide substitutions)
Majority of WCS reads,TP3D18,and TPB12C6 reads call G, One WCS read calls T; type 1 (single nucleotide substitutions)
Majority of WCS reads,TP3D18 and TPB12C6 reads call G, One WCS read calls T; type 1 (single nucleotide substitutions)
Majority of WCS and TPB12C6 reads call C, One WCS read calls A; type 1 (single nucleotide substitutions)
GPI-Anchor Signal predicted for Tb927.1.250 by DGPI v2.04 with cleavage site probability 0.30960003 near 89
leucine-rich repeat protein (LRRP), putative
Majority of WCS reads call A, One TP11F10 read calls C; type 1 (single nucleotide substitutions); mis-sense mutation at 232 in Tb927.1.290 Q -> H
Majority of WCS reads call G, One TP11F10 read calls C; type 1 (single nucleotide substitutions); mis-sense mutation at 249 in Tb927.1.290 G -> A
Majority of WCS reads call G, One TP11F10 read calls A; type 1 (single nucleotide substitutions); silent mutation in Tb927.1.290
Majority of WCS reads call T, One TP11F10 read calls C; type 1 (single nucleotide substitutions); silent mutation in Tb927.1.290
Majority of WCS reads call A, One TP11F10 read calls T; type 1 (single nucleotide substitutions); mis-sense mutation at 282 in Tb927.1.290 K -> M
Majority of WCS reads call G, One TP11F10 read calls T; type 1 (single nucleotide substitutions); mis-sense mutation at 285 in Tb927.1.290 E -> D
RHS5 sequence at 5'-end of highly degenerate RHS5-ingi chimeric pseudogene
ingi element inserted into RHS5 chimera to produce RHS5-ingi degenerate chimeric pseudogene
Majority of WCS and TP3D18 reads call A, One WCS read calls G; type 1 (single nucleotide substitutions)
RHS5 sequence at 3' end of RHS-RIME chimeric pseudogene
Majority of WCS,TP3D18,TPB12C6 and TPB15A20;call 8 T, One WCS calls 11 T; type 3 (insertion/deletion of 3 nucleotides)
RHS5 sequence at 5'-end of RHS5-ingi pseudogene
Majority of WCS,TP3D18 and TPB15A20 reads call C, One WCS read calls A; type 1 (single nucleotide substitutions); mis-sense mutation at 1212 in Tb927.1.370 G -> C
Majority of WCS,TP3D18 and TPB15A20 reads call C, One WCS read calls A; type 1 (single nucleotide substitutions); mis-sense mutation at 1210 in Tb927.1.370 D -> Y
Majority of WCS,TP3D18,TP16A7 and TPB15A20 reads call T, One WCS read calls G; type 1 (single nucleotide substitutions); mis-sense mutation at 1163 in Tb927.1.370 N -> H
1 probable transmembrane helix predicted for Tb927.1.390 by TMHMM2.0 at aa 53-75
Signal peptide predicted for Tb927.1.400 by SignalP 2.0 HMM (Signal peptide probabilty 0.908, signal anchor probability 0.000) with cleavage site probability 0.570 between residues 31 and 32
Majority of WCS,TP3D18,TPB12C6 and TPB15A20 reads call G, One WCS read calls A; type 1 (single nucleotide substitutions)
Majority of WCs,TP16A7 and TP3D18 reads call A, One WCS read calls T; type 1 (single nucleotide substitutions)
Majority of WCS,TP16A7 AND TP3D18 reads call G, One WCS read calls A; type 1 (single nucleotide substitutions)
Majority of WCS,TP16A7 and TP3D18 reads A or T;One WCS read calls G or C; type 9 (single nucleotide substitutions)
Majority of WCS,TP16A7 and TP3D18 reads C, One WCS read calls T; type 1 (single nucleotide substitutions)
Majority of WCS,TP16A7 and TP3D18 reads call A, One WCS read calls G; type 1 (single nucleotide substitutions)
Majority of WCS,TP16A7 and TP3D18 reads call G, One WCS read calls C; type 1 (single nucleotide substitutions)
Majority of WCS,TP3D18 and TP16A7 call T, One WCS read calls C; type 1 (single nucleotide substitutions)
Majority of WCS,TP3D18 and TP16A7 reads call C, One WCS read calls T; type 1 (single nucleotide substitutions)
Majority of WCS,TP16A7 and TP3D18 reads; call 6 T;One WCS read calls 5 T; type 2 (single nucleotide insertions/deletions)
Majority of WCS,TP3D18 and TP16A7 reads call G, Three WCS reads call A; type 1 (single nucleotide substitutions)
Majority of WCS,TP3D18 and TP16A7 reads call G, One WCS read calls A; type 1 (single nucleotide substitutions)
retrotransposon hot spot (RHS) protein; retrotransposon hot spot protein 5 (RHS5)
Majority of WCS,TP3D18 and TPB15A20 reads call A, One WCS calls G; type 1 (single nucleotide substitutions); mis-sense mutation at 219 in Tb927.1.420 S -> G
RHS2 sequence at 5'-end of RHS2-ingi-RHS6 chimeric pseudogene
Majority of WCS,TPB12C6 and TPB15A20 call T, One WCS read calls C; type 1 (single nucleotide substitutions)
ingi element apparently inserted into a pseudogene for a retrotransposon hot spot protein, RHS2-e (an RHS2-RHS6 chimera); ingi truncated (5') (pers. comm. F. Bringaud)
RHS6 sequence at 3'-end of RHS2-ingi-RHS6 chimeric pseudogene
Majority of WCS,TP3D18 and; TPB12C6 reads call 8 T, One WCS read calls 9 T and;one WCS read calls 10 T; type 2 (single nucleotide insertions/deletions)
ingi element; part of RHS1-ingi chimera; ingi - one point mutation (pers. comm. F. Bringaud)
RHS1f sequence at 5'-end of RHS1-ingi chimeric pseudogene
2 probable transmembrane helices predicted for Tb927.1.460 by TMHMM2.0 at aa 7-29 and 44-66
Majority of WCS,TP16A7,TP3D18,TPB12C6 and TPB15A20 reads call C, Three TP20A12 reads call T; type 1 (single nucleotide substitutions)
Majority of WCS,TP3D18,TP16A7 and TP20A12 reads call G, One WCS read calls A; type 1 (single nucleotide substitutions)
Majority of WCS,TP3D18,TP16A7,TPB15A20 and TP20A12 reads call G, One WCS read calls A; type 1 (single nucleotide substitutions)
Majority of WCS,TP20A12,TPB15A20,;TP3D18 and TPB12C6 reads call 6 G, One WCS read calls 5 G; type 2 (single nucleotide insertions/deletions)
Majority of WCS and TPB12C6 reads call T, One WCS and TP20A12 call A; type 1 (single nucleotide substitutions)
Majority of WCS and TPB12C6 reads call G, One WCS and TP20A12 call A; type 1 (single nucleotide substitutions)
Majority of WCS and TP3D18 reads call G, One WCS read calls A; type 1 (single nucleotide substitutions); silent mutation in Tb927.1.480
Majority of WCS,TP3D18,TP16A7 and TPB15A20 reads call C, One WCS read calls T; type 1 (single nucleotide substitutions); silent mutation in Tb927.1.480
Majority of WCS,TP16A7,TP3D18 and TPB15A20 call G, One WCS read calls A; type 1 (single nucleotide substitutions); mis-sense mutation at 499 in Tb927.1.480 V -> I
Majority of WCS,TP16A7,TP3D18 and TPB15A20 call T, One WCS read calls C; type 1 (single nucleotide substitutions); mis-sense mutation at 502 in Tb927.1.480 V -> A
Majority of WCS,TP16A7,TP3D18 and TPB15A20 call A, Two WCS reads calls G; type 1 (single nucleotide substitutions); silent mutation in Tb927.1.480
Majority of WCS,TP16A7,TP3D18 and TPB15A20 call T, Two WCS reads calls C; type 1 (single nucleotide substitutions); silent mutation in Tb927.1.480
Majority of WCS,TP16A7,TP3D18 and TPB15A20 call A, Two WCS reads calls G; type 1 (single nucleotide substitutions); mis-sense mutation at 618 in Tb927.1.480 N -> S
Majority of WCS,TP16A7,TP3D18 and TPB15A20 call A, Two WCS reads calls C; type 1 (single nucleotide substitutions); mis-sense mutation at 630 in Tb927.1.480 I -> L
Insertion of AATAATAAT in one WCS read; type 5 (insertion/deletion of more than 3 nucleotides in microsatellites)
RHS5 sequence at 5'-end of RHS5-ingi chimeric pseudogene
ingi element fused to to 3'-end of trancated RHS5 sequence, forming RHS5-ingi chimeric pseudogene; ingi -several point mutations (pers. comm. F. Bringaud)
Majority of WCS,TPB15A20,TP3D18,TP20A12 and TP7E4 reads call G, One WCS read calls A; type 1 (single nucleotide substitutions)
Majority of WCS,TPB15A20,TP3D18 and TP7E4 reads call C, One WCS read calls T; type 1 (single nucleotide substitutions)
ingi. truncated (3') (pers. comm. F. Bringaud)
Majority of WCS,TP7E4,TP3D18 and TPB12C6 reads call C, Three WCS reads call T, One TP20A12 read calls T,; type 1 (single nucleotide substitutions)
GPI-Anchor Signal predicted for Tb927.1.530 by DGPI v2.04 with cleavage site probability 0.702 near 253
Majority of WCS,TPB15A20,TP7E4 and TPB12C6 reads call T, Two TP20A12 reads call C; type 1 (single nucleotide substitutions)
DNA-directed RNA polymerase III, putative
Majority of WCS,TP3D18,TP7E4 and TPB15A20 reads call T, Two TP20A12 and one WCS reads call C; type 1 (single nucleotide substitutions); silent mutation in Tb927.1.540
Majority of WCS,TPB15A20,TPB12C6,TP3D18 and TP7E4 reads call C, One WCS read calls T; type 1 (single nucleotide substitutions); mis-sense mutation at 757 in Tb927.1.540 D -> N
Majority of WCS,TPB15A20,TP3D18 and TPB12C6 reads call A, Three TP20A12 reads call G; type 1 (single nucleotide substitutions); silent mutation in Tb927.1.540
Majority of WCS,TPB15A20,TPB12C6 and TP3D18 reads call A, One WCS read calls C; type 1 (single nucleotide substitutions); silent mutation in Tb927.1.540
Signal peptide predicted for Tb927.1.550 by SignalP 2.0 HMM (Signal peptide probabilty 0.622, signal anchor probability 0.001) with cleavage site probability 0.487 between residues 21 and 22
Majority of WCS,TP7E4,TP3D18,TPB12C6 and TPB15A20 reads call A, One WCS read calls G; type 1 (single nucleotide substitutions); silent mutation in Tb927.1.560
Majority of WCS,TP3D18,TP7E4,TP3D18 and TPB12C6 reads call G, One WCS read calls A; type 1 (single nucleotide substitutions)
phosphate-repressible phosphate permease, putative
Majority of WCS,TP3D18 and TP7E4 reads call C, Two WCS reads call T; type 1 (single nucleotide substitutions)
Majority of genomic shotgun,TPB15A20,TP3D18 and TP7E4 reads call A, Two TP20A12 reads call C; type 1 (single nucleotide substitutions)
2 probable transmembrane helices predicted for Tb927.1.590 by TMHMM2.0 at aa 20-42 and 52-74
Majority of WCS,TP3D18,TP7E4,TPB15A20 and;TP16A7 reads call 10 G, One WCS and TP20A12 read call 12G; type 6 (insertion/deletion of 2 nucleotides)
Signal anchor predicted for Tb927.1.590 by SignalP 2.0 HMM (Signal peptide probabilty 0.101, signal anchor probability 0.876) with cleavage site probability 0.083 between residues 33 and 34
Majority of WCS,TP3D18,TP20A12,;TP7E4 and TPB15A20 reads call C, One WCS read calls G; type 1 (single nucleotide substitutions); mis-sense mutation at 17 in Tb927.1.590 R -> T
Majority of WCS,TP3D18,TP20A12,TP7E4 and TPB15A20 reads call T, One WCS read calls C; type 1 (single nucleotide substitutions); silent mutation in Tb927.1.590
One WCS,TP3D18 and TP7E4 call T, Two WCS and TP20A12 call C; type 1 (single nucleotide substitutions); silent mutation in Tb927.1.600
Signal anchor predicted for Tb927.1.620 by SignalP 2.0 HMM (Signal peptide probabilty 0.258, signal anchor probability 0.702) with cleavage site probability 0.170 between residues 35 and 36
anti-silencing protein ASF 1 like protein, putative
Majority of WCS,TP7E4 and TPB15A2 call A, One WCS read calls G; type 1 (single nucleotide substitutions); silent mutation in Tb927.1.640
Majority of WCS,TP7E4,TPB15A20 and TP3D18 reads call T, One WCS read calls C; type 1 (single nucleotide substitutions); silent mutation in Tb927.1.640
Majority of WCS,TP7E4 and TPB15A20 reads call T, One TP20A12 read calls C; type 1 (single nucleotide substitutions); silent mutation in Tb927.1.640
Majority of WCS,TPB15A20 and TP7E4 reads call C, One WCS and one TP20A12 read call T; type 1 (single nucleotide substitutions); silent mutation in Tb927.1.640
Majority of WCS,TPB15A20 and TP7E4 reads call A, One WCS and one TP20A12 read call C; type 1 (single nucleotide substitutions); mis-sense mutation at 781 in Tb927.1.640 V -> G
Majority of WCS,TPB15A20 and TP7E4 reads call C, One WCS and one TP20A12 read call A; type 1 (single nucleotide substitutions); mis-sense mutation at 780 in Tb927.1.640 G -> V
Majority of WCS,TP7E4 and TPB15A20 call C, One WCS and TP20A12 call A; type 1 (single nucleotide substitutions); silent mutation in Tb927.1.640
Majority of WCS,TP7E4,TP3D18 and TPB15A20 reads call C, One WCS and TP20A12 call T; type 1 (single nucleotide substitutions); mis-sense mutation at 711 in Tb927.1.640 V -> I
Majority of WCS,TP7E4,TP3D18 and TPB15A20 reads call T, One WCS and TP20A12 call G; type 1 (single nucleotide substitutions); mis-sense mutation at 710 in Tb927.1.640 T -> P
Majority of WCS,TP7E4,TPB15A20 and TP3D18 reads call A, One WCS and TP20A12 call G; type 1 (single nucleotide substitutions); silent mutation in Tb927.1.640
Majority of WCS,TPB15A20,TP7E4 and TP3D18 reads call G, One WCS and TP20A12 call A; type 1 (single nucleotide substitutions); silent mutation in Tb927.1.640
Majority of WCS,TPB15A20,TP3D18 and TP7E4 reads call T, Two TP20A12 reads call C; type 1 (single nucleotide substitutions); mis-sense mutation at 602 in Tb927.1.640 T -> A
Majority of WCS and TP7E4 reads call C, TP20A12 reads call T; type 1 (single nucleotide substitutions); silent mutation in Tb927.1.640
Majority of WCS,TP7E4 and TPB15A20 reads call A, One TP20A12 read calls G; type 1 (single nucleotide substitutions); silent mutation in Tb927.1.640
Majority of TP7E4 and TPB12C6 reads call G, One TP3D18 read calls A; type 1 (single nucleotide substitutions); silent mutation in Tb927.1.640
Majority of WCS,TP3D18,TP7E4 and TPB15A20 reads call G, One TP3D18 read calls A; type 1 (single nucleotide substitutions); silent mutation in Tb927.1.640
Majority of WCS,TP7E4,TP20A12 and TPB15A20 reads call A, One TP3D18 read calls G; type 1 (single nucleotide substitutions); silent mutation in Tb927.1.640
1 probable transmembrane helix predicted for Tb927.1.660 by TMHMM2.0 at aa 29-51
Signal anchor predicted for Tb927.1.660 by SignalP 2.0 HMM (Signal peptide probabilty 0.022, signal anchor probability 0.978) with cleavage site probability 0.017 between residues 45 and 46
Majority of WCS,TP7E4,TP3D18 and TPB15A20 reads call A, One WCS read calls C; type 1 (single nucleotide substitutions)
Majority of WCS,TP7E4 and TP3D18 reads call G, Two TP20A12 reads call A
Majority of WCS,TP3D18 and TPB15A20 reads call T, One TP20A12 read calls C; type 1 (single nucleotide substitutions)
Majority of WCS,TP3D18,TP7E4 and TPB15A20 reads call A, One WCS read and TP20A12 call G; type 1 (single nucleotide substitutions)
Majority of WCS,TPB15A20,TP3D18 and TP7E4 reads call C, One WCS read calls T; type 1 (single nucleotide substitutions); mis-sense mutation at 216 in Tb927.1.690 R -> K
Majority of WCS,TP7E4,TP20A12 and TPB15A20 reads call T, One WCS read calls C; type 1 (single nucleotide substitutions)
Majority of WCS,TP7E4,TP20A12 and TPB15A20 reads call G, One WCS read calls A; type 1 (single nucleotide substitutions)
Majority of WCS,TP7E4,TP20A12 and TPB15A20 reads call G, One WCS read calls C; type 1 (single nucleotide substitutions); mis-sense mutation at 377 in Tb927.1.710 D -> E
Majority of WCS,TP7E4, TP20A12 and TPB15A20 reads call T, One WCS read calls C; type 1 (single nucleotide substitutions); mis-sense mutation at 367 in Tb927.1.710 H -> R
Majority of WCS and TP7E4 reads call A, One TP20A12 read calls G; type 1 (single nucleotide substitutions); mis-sense mutation at 902 in Tb927.1.750 S -> P
42 bp repeat (MS42); highly polymorphic between isolates. Array contains approx. 17.8 repeat units; highly conserved with 9 purine and 1 pyrimidine substitution
Majority of WCS reads call 11 G;Two WCS reads call 8 G; type 3 (insertion/deletion of 3 nucleotides)
3 probable transmembrane helices predicted for Tb927.1.770 by TMHMM2.0 at aa 4-26, 33-52 and 57-79
Signal peptide predicted for Tb927.1.770 by SignalP 2.0 HMM (Signal peptide probabilty 0.908, signal anchor probability 0.089) with cleavage site probability 0.601 between residues 18 and 19
Signal peptide predicted for Tb927.1.790 by SignalP 2.0 HMM (Signal peptide probabilty 0.978, signal anchor probability 0.001) with cleavage site probability 0.334 between residues 27 and 28
3 probable transmembrane helices predicted for Tb927.1.800 by TMHMM2.0 at aa 5-27, 34-56 and 66-88
Signal peptide predicted for Tb927.1.800 by SignalP 2.0 HMM (Signal peptide probabilty 0.883, signal anchor probability 0.061) with cleavage site probability 0.329 between residues 24 and 25
3 probable transmembrane helices predicted for Tb927.1.810 by TMHMM2.0 at aa 13-30, 37-59 and 79-98
2 probable transmembrane helices predicted for Tb927.1.840 by TMHMM2.0 at aa 29-51 and 162-181
Signal peptide predicted for Tb927.1.840 by SignalP 2.0 HMM (Signal peptide probabilty 0.940, signal anchor probability 0.040) with cleavage site probability 0.728 between residues 42 and 43
Signal peptide predicted for Tb927.1.850 by SignalP 2.0 HMM (Signal peptide probabilty 0.619, signal anchor probability 0.048) with cleavage site probability 0.442 between residues 30 and 31
GPI-Anchor Signal predicted for Tb927.1.860 by DGPI v2.04, no cleavage site predicted
1 probable transmembrane helix predicted for Tb927.1.860 by TMHMM2.0 at aa 7-29
Signal peptide predicted for Tb927.1.860 by SignalP 2.0 HMM (Signal peptide probabilty 0.999, signal anchor probability 0.001) with cleavage site probability 0.770 between residues 18 and 19
Majority of WCS reads call A, One WCS read calls C; type 1 (single nucleotide substitutions); mis-sense mutation at 2847 in Tb927.1.880 S -> R
Majority of WCS reads call C, Two WCS reads call T; type 1 (single nucleotide substitutions); mis-sense mutation at 2110 in Tb927.1.880 V -> M
1 probable transmembrane helix predicted for Tb927.1.890 by TMHMM2.0 at aa 21-43
developmentally regulated phosphoprotein
Majority of WCS,TP1J20 and TP29E6 reads call G, One TP27E7 read calls A; type 1 (single nucleotide substitutions); mis-sense mutation at 102 in Tb927.1.1010 V -> I
Majority of WCS,TP1J20 and TP29E6 reads call A, One TP27E7 read calls T; type 1 (single nucleotide substitutions)
WCS and TP29E6 call A, TP27E7 and TP1J20 call G; type 1 (single nucleotide substitutions)
hypothetical protein, conserved; leucine-rich repeat protein (LRRP), putative
WCS, TP1J20 and TP29E6 call C, TP27E7 calls T; type 1 (single nucleotide substitutions); mis-sense mutation at 40 in Tb927.1.1030 R -> W
Signal anchor predicted for Tb927.1.1050 by SignalP 2.0 HMM (Signal peptide probabilty 0.001, signal anchor probability 0.871) with cleavage site probability 0.000 between residues 53 and 54
Majority of WCS, TP29E6 and TP1J10 call G, Two WCS reads call A; type 1 (single nucleotide substitutions); mis-sense mutation at 138 in Tb927.1.1090 G -> S
Signal peptide predicted for Tb927.1.1110 by SignalP 2.0 HMM (Signal peptide probabilty 0.798, signal anchor probability 0.000) with cleavage site probability 0.464 between residues 39 and 40
WCS, TP29E6 and TP1J20 call G, TP27E7 calls C; type 1 (single nucleotide substitutions)
Insertion of TGTA in TP27E7; type 5 (insertion/deletion of more than 3 nucleotides in microsatellites)
glycerol-3-phosphate dehydrogenase (FAD-dependent), putative
Signal peptide predicted for Tb927.1.1130 by SignalP 2.0 HMM (Signal peptide probabilty 0.914, signal anchor probability 0.082) with cleavage site probability 0.415 between residues 24 and 25
1 probable transmembrane helix predicted for Tb927.1.1130 by TMHMM2.0 at aa 12-31
Majority of WCS and TP29E6 call G, One WCS read calls C; type 1 (single nucleotide substitutions)
Signal anchor predicted for Tb927.1.1140 by SignalP 2.0 HMM (Signal peptide probabilty 0.268, signal anchor probability 0.727) with cleavage site probability 0.195 between residues 39 and 40
1 probable transmembrane helix predicted for Tb927.1.1140 by TMHMM2.0 at aa 21-43
Deletion of TCT in two WCS reads and TP27E7; type 3 (insertion/deletion of 3 nucleotides)
Signal peptide predicted for Tb927.1.1160 by SignalP 2.0 HMM (Signal peptide probabilty 0.874, signal anchor probability 0.006) with cleavage site probability 0.263 between residues 32 and 33
Signal peptide predicted for Tb927.1.1180 by SignalP 2.0 HMM (Signal peptide probabilty 0.619, signal anchor probability 0.236) with cleavage site probability 0.464 between residues 24 and 25
Majority of WCS and TP29E6 call 10 T, Two WCS reads call 11 T; type 2 (single nucleotide insertions/deletions)
Signal peptide predicted for Tb927.1.1230 by SignalP 2.0 HMM (Signal peptide probabilty 0.673, signal anchor probability 0.001) with cleavage site probability 0.489 between residues 21 and 22
Majority of WCS and TP1J10 call G, One WCS read calls A; type 1 (single nucleotide substitutions)
Majority of WCS and TP29E6 call G, One WCS read and TP27E7 call A; type 1 (single nucleotide substitutions)
Majority of WCS call T, Two WCS reads and TP27E7 call A; type 1 (single nucleotide substitutions)
cytidine triphosphate synthase, putative
GPI-Anchor Signal predicted for Tb927.1.1250 by DGPI v2.04 with cleavage site probability 0.25800002 near 83
Signal peptide predicted for Tb927.1.1250 by SignalP 2.0 HMM (Signal peptide probabilty 0.973, signal anchor probability 0.002) with cleavage site probability 0.467 between residues 18 and 19
unlikely gene, opposite strand to gene cluster
2 probable transmembrane helices predicted for Tb927.1.1260 by TMHMM2.0 at aa 37-59 and 129-151
Signal anchor predicted for Tb927.1.1260 by SignalP 2.0 HMM (Signal peptide probabilty 0.001, signal anchor probability 0.967) with cleavage site probability 0.001 between residues 52 and 53
homocysteine S-methyltransferase, putative
Signal anchor predicted for Tb927.1.1280 by SignalP 2.0 HMM (Signal peptide probabilty 0.001, signal anchor probability 0.999) with cleavage site probability 0.000 between residues 47 and 48
2 probable transmembrane helices predicted for Tb927.1.1280 by TMHMM2.0 at aa 15-37 and 50-72
2 probable transmembrane helices predicted for Tb927.1.1290 by TMHMM2.0 at aa 43-65 and 75-97
2 probable transmembrane helices predicted for Tb927.1.1300 by TMHMM2.0 at aa 130-152 and 199-218
Signal peptide predicted for Tb927.1.1310 by SignalP 2.0 HMM (Signal peptide probabilty 0.832, signal anchor probability 0.149) with cleavage site probability 0.215 between residues 22 and 23
1 probable transmembrane helix predicted for Tb927.1.1310 by TMHMM2.0 at aa 2-21
Signal peptide predicted for Tb927.1.1320 by SignalP 2.0 HMM (Signal peptide probabilty 0.969, signal anchor probability 0.010) with cleavage site probability 0.670 between residues 16 and 17
Majority of WCS, TP29E6 and TP1J10 call G, One WCS read calls A; type 1 (single nucleotide substitutions); mis-sense mutation at 1 in Tb927.1.1320 M -> I
1 probable transmembrane helix predicted for Tb927.1.1320 by TMHMM2.0 at aa 5-27
GPI-Anchor Signal predicted for Tb927.1.1320 by DGPI v2.04 with cleavage site probability 0.1462 near 50
Majority of WCS and TP1J10 call C, One WCS read and TP27E7 call T; type 1 (single nucleotide substitutions); mis-sense mutation at 165 in Tb927.1.1330 A -> V
FG-GAP repeat protein; intergrin alpha chain protein
Majority of WCS and TP1J20 call A, One WCS read and TP27E7 call G; type 1 (single nucleotide substitutions)
Majority of WCS, TP29E6 and TP1J20 call G, Two WCS reads and TP27E7 call A; type 1 (single nucleotide substitutions); mis-sense mutation at 193 in Tb927.1.1340 S -> N
Majority of WCS, TP29E6 call G, One WCS read and TP27E7 call C; type 1 (single nucleotide substitutions); mis-sense mutation at 248 in Tb927.1.1340 R -> T
Majority of WCS, TP29E6 call T, One WCS read and TP27E7 call G; type 1 (single nucleotide substitutions); mis-sense mutation at 249 in Tb927.1.1340 D -> E
Majority of WCS and TP29E6 call G, One WCS read calls C; type 1 (single nucleotide substitutions); mis-sense mutation at 384 in Tb927.1.1340 E -> D
Majority of WCS and TP29E6 call A, One WCS read calls G; type 1 (single nucleotide substitutions); mis-sense mutation at 406 in Tb927.1.1340 S -> G
Majority of WCS call C, Two WCS reads call T; type 1 (single nucleotide substitutions)
Majority of WCS call G, Two WCS reads call A; type 1 (single nucleotide substitutions)
Majority of WCS calls A, Two WCS reads call G; type 1 (single nucleotide substitutions)
Majority of WCS, TP29E6 and TP1J20 call 14 A, One WCS read and TP27E7 call 13 A; type 2 (single nucleotide insertions/deletions)
Majority of WCS and TP29E6 call T, Two WCS reads call C; type 1 (single nucleotide substitutions)
Majority of WCS, TP29E6 and TP1J20 call G, Three WCS reads call A; type 1 (single nucleotide substitutions); mis-sense mutation at 21 in Tb927.1.1350 S -> N
GPI-Anchor Signal predicted for Tb927.1.1360 by DGPI v2.04 with cleavage site probability 0.696 near 83
Signal anchor predicted for Tb927.1.1360 by SignalP 2.0 HMM (Signal peptide probabilty 0.012, signal anchor probability 0.988) with cleavage site probability 0.004 between residues 19 and 20
2 probable transmembrane helices predicted for Tb927.1.1360 by TMHMM2.0 at aa 7-26 and 41-63
WCS calls A, TP27E7 calls G; type 1 (single nucleotide substitutions)
serine/threonine protein phosphatase 2a regulatory subunit, putative
Majority of WCS reads call C, One WCS read and TP27E7 call T; type 1 (single nucleotide substitutions)
Majority of WCS reads call 9 T, One WCS read and TP27E7 call 10 T; type 2 (single nucleotide insertions/deletions)
Insertion of ATACAT in TP27E7; type 5 (insertion/deletion of more than 3 nucleotides in microsatellites)
WCS calls G, TP28N5 and TP27E7 call A; type 1 (single nucleotide substitutions)
WCS calls A, TP28N5 and TP27E7 call G; type 1 (single nucleotide substitutions); mis-sense mutation at 143 in Tb927.1.1390 I -> M
Majority of WCS reads call A, One WCS read and TP27E7 call T; type 1 (single nucleotide substitutions)
Deletion of ATATATATAT in one WCS read and TP27E7; type 5
Majority of WCS reads call 9 A, One WCS read and TP27E7 call 8 A; type 2 (single nucleotide insertions/deletions)
Insertion of GT in three WCS reads; type 5
Majority of WCS reads and TP1J20 call 13 A, Three WCS reads call 15 A; type 6 (insertion/deletion of 2 nucleotides)
Majority of WCS reads and TP1J20 call 8 T, One WCS read calls 9 T; type 2 (single nucleotide insertions/deletions)
1 probable transmembrane helix predicted for Tb927.1.1400 by TMHMM2.0 at aa 42-64
3 probable transmembrane helices predicted for Tb927.1.1410 by TMHMM2.0 at aa 40-62, 67-89 and 96-118
Signal anchor predicted for Tb927.1.1410 by SignalP 2.0 HMM (Signal peptide probabilty 0.006, signal anchor probability 0.989) with cleavage site probability 0.001 between residues 63 and 64
Majority of WCS reads and TP29E6 call A, One WCS read calls G; type 1 (single nucleotide substitutions)
3 probable transmembrane helices predicted for Tb927.1.1430 by TMHMM2.0 at aa 13-45, 65-87 and 122-144
WCS, TP29E6 and TP1J10 call 11 A, TP27E7 calls 10 A; type 2 (single nucleotide insertions/deletions)
Deletion of CCCTCCCTCC in TP27E7; type 5
WCS and TP26E6 call A, TP27E7 calls G; type 1 (single nucleotide substitutions)
Signal anchor predicted for Tb927.1.1430 by SignalP 2.0 HMM (Signal peptide probabilty 0.000, signal anchor probability 1.000) with cleavage site probability 0.000 between residues 47 and 48
Signal peptide predicted for Tb927.1.1440 by SignalP 2.0 HMM (Signal peptide probabilty 0.725, signal anchor probability 0.013) with cleavage site probability 0.370 between residues 22 and 23
Signal peptide predicted for Tb927.1.1450 by SignalP 2.0 HMM (Signal peptide probabilty 0.823, signal anchor probability 0.000) with cleavage site probability 0.527 between residues 17 and 18
Majority of WCS and TP29E6 call T, Two WCS reads and TP28N5 call T; type 1 (single nucleotide substitutions)
1 probable transmembrane helix predicted for Tb927.1.1460 by TMHMM2.0 at aa 10-32
3 probable transmembrane helices predicted for Tb927.1.1480 by TMHMM2.0 at aa 25-42, 52-71 and 78-100
Majority of WCS and TP29E6 call 10 A, One WCS read calls 21 A; type 6 (insertion/deletion of 6 or more nucleotides)
GPI-Anchor Signal predicted for Tb927.1.1500 by DGPI v2.04 with cleavage site probability 0.442 near 649
Majority of WCS and TP1J20 call 10 T, One WCS read calls 8 T; type 6 (insertion/deletion of 2 nucleotides)
4 probable transmembrane helices predicted for Tb927.1.1510 by TMHMM2.0 at aa 4-26, 45-67, 71-93 and 105-127
Signal anchor predicted for Tb927.1.1510 by SignalP 2.0 HMM (Signal peptide probabilty 0.000, signal anchor probability 0.996) with cleavage site probability 0.000 between residues 16 and 17
Majority of WCS, TP1J10 and TP29E6 call G, One WCS read calls A; type 1 (single nucleotide substitutions)
Insertion of GAAAAA in one WCS read; type 5
Deletion of A in one WCS read; type 2 (single nucleotide insertions/deletions)
Signal anchor predicted for Tb927.1.1520 by SignalP 2.0 HMM (Signal peptide probabilty 0.013, signal anchor probability 0.985) with cleavage site probability 0.005 between residues 29 and 30
3 probable transmembrane helices predicted for Tb927.1.1520 by TMHMM2.0 at aa 13-32, 47-69 and 82-104
Deletion of ATATATATATATAT in one WCS read; type 5
Majority of WCS reads call T, Two WCS reads and TP27E7 call C; type 1 (single nucleotide substitutions)
Majority of WCS reads call C, Two WCS reads and TP27E7 call T; type 1 (single nucleotide substitutions)
Majority of WCS reads call T, One WCS read and TP27E7 call C; type 1 (single nucleotide substitutions)
Majority of WCS reads call 6 A, One WCS read calls 7 A; type 2 (single nucleotide insertions/deletions)
Deletion of T in TP28N5 and TP27E7; type 2 (single nucleotide insertions/deletions)
WCS and TP1J20 call T, TP28N5 and TP27E7 call A; type 1 (single nucleotide substitutions)
WCS call 9 T, TP27E7 calls 10 T; type 2 (single nucleotide insertions/deletions)
WCS and TP29E6 call T, TP27E7 calls A; type 1 (single nucleotide substitutions)
Signal peptide predicted for Tb927.1.1540 by SignalP 2.0 HMM (Signal peptide probabilty 0.736, signal anchor probability 0.009) with cleavage site probability 0.360 between residues 20 and 21
Majority of WCS and TP1J20 call C, One WCS read and TP27E7 call T; type 1 (single nucleotide substitutions)
WCS and TP1J20 call T, TP27E7 calls C; type 1 (single nucleotide substitutions)
WCS, TP29E6 and TP1J20 call G, TP10C4 calls A; type 1 (single nucleotide substitutions)
Majority of WCS, TP29E6 and TP1J20 call A, One WCS read and TP10C4 call G; type 1 (single nucleotide substitutions)
Majority of WCS, TP29E6 and TP1J20 call T, One WCS read and TP10C4 call C; type 1 (single nucleotide substitutions)
WCS and TP1J20 call A, TP10C4 calls G; type 1 (single nucleotide substitutions); mis-sense mutation at 331 in Tb927.1.1550 S -> G
Majority of WCS and TP29E6 call T, One WCS read and TP10C4 call C; type 1 (single nucleotide substitutions); mis-sense mutation at 539 in Tb927.1.1550 S -> P
vesicular-fusion protein NsF; N-ethylmaleimide sensitive factor (NsF)
Majority of WCS reads call G, One WCS read, TP10C4 and TP28N5 call A; type 1 (single nucleotide substitutions)
Majority of WCS calls 10T, Two WCS reads, TP10C4, TP27E7 and TP28N5 call 9 T; type 2 (single nucleotide insertions/deletions)
Majority of WCS and TP1J20 call A, One WCS read, TP10C4 and TP28N5 call G; type 1 (single nucleotide substitutions)
Majority of WCS calls 10 T, One WCS read and TP10C4 call 9 T; type 2 (single nucleotide insertions/deletions)
Majority of WCS calls C, One WCS read and TP10C4 call T; type 1 (single nucleotide substitutions)
Majority of WCS and TP29E6 call C, Three WCS reads and TP10C4 call T; type 1 (single nucleotide substitutions)
Majority of WCS and TP29E6 call 10 T, Three WCS reads and TP10C4 call 11 T; type 2 (single nucleotide insertions/deletions)
Majority of WCS and TP29E6 call A, Three WCS reads and TP10C4 call G; type 1 (single nucleotide substitutions); mis-sense mutation at 89 in Tb927.1.1570 D -> G
cytochrome c oxidase assembly factor; electron transport protein SCO1/2
Signal anchor predicted for Tb927.1.1580 by SignalP 2.0 HMM (Signal peptide probabilty 0.001, signal anchor probability 0.865) with cleavage site probability 0.000 between residues 64 and 65
Majority of WCS and TP1J20 call 10 T, Two WCS reads and TP10C4 call 11 T; type 2 (single nucleotide insertions/deletions)
GPI-Anchor Signal predicted for Tb927.1.1590 by DGPI v2.04, no cleavage site predicted
Signal peptide predicted for Tb927.1.1590 by SignalP 2.0 HMM (Signal peptide probabilty 0.877, signal anchor probability 0.121) with cleavage site probability 0.264 between residues 20 and 21
1 probable transmembrane helix predicted for Tb927.1.1590 by TMHMM2.0 at aa 5-27
WCS calls 11 T, TP10C4 calls 8 T; type 3 (insertion/deletion of 3 nucleotides)
Majority of WCS and TP1J20 call G, Two WCS reads, TP10C4, TP27E7 and TP28N5 call A; type 1 (single nucleotide substitutions); mis-sense mutation at 187 in Tb927.1.1600 E -> K
Majority of WCS and TP1J20 call C, Two WCS reads, TP10C4 and TP27E7 call T; type 1 (single nucleotide substitutions)
Majority of WCS and TP29E6 call C, Two WCS reads, TP27E7 and TP10C4 call T; type 1 (single nucleotide substitutions)
Majority of WCS and TP29E6 call T, Two WCS reads, TP27E7 and TP10C4 call C; type 1 (single nucleotide substitutions)
Majority of WCS and TP29E6 call G, One WCS read, TP27E7 and TP10C4 call A; type 1 (single nucleotide substitutions); mis-sense mutation at 660 in Tb927.1.1600 V -> I
WCS and TP29E6 call T, TP10C4 calls G; type 1 (single nucleotide substitutions); mis-sense mutation at 748 in Tb927.1.1600 V -> G
WCS and TP1J20 call T, TP10C4, TP27E7 and TP28N5 call C; type 1 (single nucleotide substitutions)
WCS, TP29E6 and TP1J20 call G, TP10C4 calls A; type 1 (single nucleotide substitutions); mis-sense mutation at 1095 in Tb927.1.1600 G -> R
WCS, TP29E6 and TP1J20 call A, TP10C4 and TP28N5 call G; type 1 (single nucleotide substitutions)
WCS and TP29E6 call T, TP10C4 and TP28N5 call C; type 1 (single nucleotide substitutions); mis-sense mutation at 1303 in Tb927.1.1600 L -> P
WCS and TP19E6 call G, TP10C4 calls T; type 1 (single nucleotide substitutions); mis-sense mutation at 1328 in Tb927.1.1600 Q -> H
WCS and TP29E6 call T, TP10C4 calls C; type 1 (single nucleotide substitutions)
WCS and TP29E6 call A, TP10C4 and TP27E7 call G; type 1 (single nucleotide substitutions)
WCS and TP29E6 call T, TP10C4 and TP27E7 call A; type 1 (single nucleotide substitutions)
Majority of WCS and TP29E6 call A, One WCS read, TP10C4 and TP27E7 call G; type 1 (single nucleotide substitutions)
Majority of WCS and TP29E6 call T, One WCS read, TP27E7 and TP10C4 call A; type 1 (single nucleotide substitutions)
Deletion of AG in one WCS read, TP10C4 and TP27E7; type 5
Majority of WCS and TP29E6 call A, One WCS read, TP27E7 and TP10C4 call G; type 1 (single nucleotide substitutions)
Deletion of A in one WCS read, TP27E7 and TP10C4; type 2 (single nucleotide insertions/deletions)
Majority of WCS and TP29E6 call T, One WCS read, TP27E7 and TP10C4 call G; type 1 (single nucleotide substitutions)
Majority of WCS and TP29E6 call G, One WCS read, TP27E7 and TP10C4 call A; type 1 (single nucleotide substitutions)
Majority of WCS and TP29E6 call G, One WCS read, TP27E7 and TP10C4 call C; type 1 (single nucleotide substitutions)
Majority of WCS and TP29E6 call 8 G, One WCS read, TP27E7 and TP10C4 call 9 G; type 2 (single nucleotide insertions/deletions)
Majority of WCS and TP29E6 call G, One WCS read, TP27E7 and TP10C4 call T; type 1 (single nucleotide substitutions)
Majority of WCS and TP29E6 call T, One WCS read, TP27E7 and TP10C4 call C; type 1 (single nucleotide substitutions)
Majority of WCS and TP29E6 call C, One WCS read, TP27E7, TP10C4 and TP28N5 call A; type 1 (single nucleotide substitutions)
Majority of WCS and TP29E6 call G, One WCS read, TP27E7, TP10C4 and TP28N5 call A; type 1 (single nucleotide substitutions)
Majority of WCS calls G, One WCS read, TP10C4 and TP27E7 call A; type 1 (single nucleotide substitutions)
ATP-dependent DEAD/H RNA helicase, putative
Majority of WCS calls G, One WCS read, TP10C4 and TP27E7 call A; type 1 (single nucleotide substitutions); mis-sense mutation at 111 in Tb927.1.1620 G -> R
WCS calls A, TP10C4 calls G; type 1 (single nucleotide substitutions); mis-sense mutation at 436 in Tb927.1.1620 K -> E
WCS calls G, TP10C4 and TP27E7 call A; type 1 (single nucleotide substitutions)
WCS calls G, TP10C4 and TP27E7 call C; type 1 (single nucleotide substitutions)
Majority of WCS calls T, Three WCS reads, TP10C4, TP27E7 and TP28N5 call G; type 1 (single nucleotide substitutions)
Majority of WCS calls C, One WCS read, TP27E7 and TP10C4 call T; type 1 (single nucleotide substitutions)
Majority of WCS and TP1J20 call C, One WCS read and TP10C4 call G; type 1 (single nucleotide substitutions); mis-sense mutation at 53 in Tb927.1.1650 P -> A
WCS calls T, TP10C4 and TP27E7 call A; type 1 (single nucleotide substitutions)
Majority of WCS calls C, One WCS read and TP10C4 call G; type 1 (single nucleotide substitutions); mis-sense mutation at 182 in Tb927.1.1660 P -> A
Insertion of T in TP27E7 and TP10C4; type 2 (single nucleotide insertions/deletions)
Majority of WCS calls A, Two WCS reads, TP10C4 and TP27E7 call G; type 1 (single nucleotide substitutions)
Majority of WCS calls C, Two WCS reads, TP27E7 and TP10C4 call T; type 1 (single nucleotide substitutions)
Majority WCS calls A, One WCS read and TP27E7 call G; type 1 (single nucleotide substitutions)
WCS calls T, TP10C4 calls C; type 1 (single nucleotide substitutions)
Insertion of TA in one WCS read, TP27E7 and TP10C4; type 6 (insertion/deletion of 2 nucleotides)
WCS calls G, TP10C4 and TP28N5 call A; type 1 (single nucleotide substitutions); mis-sense mutation at 103 in Tb927.1.1680 V -> I
RNA-editing complex protein; nuclease; KREPB1
WCS calls 12 T, TP10C4 calls 14 T; type 6 (insertion/deletion of 2 nucleotides)
WCS call 9 T.; TP10C4 calls 10 T; type 2 (single nucleotide insertions/deletions)
Deletion of TG in three WCS reads, TP8B6 and TP10C4; type 5
WCS calls 11 T, TP10C4 calls 12 T; type 2 (single nucleotide insertions/deletions)
Majority of WCS calls G, One WCS read and TP10C4 call A; type 1 (single nucleotide substitutions); mis-sense mutation at 12 in Tb927.1.1710 G -> D
Majority of WCS calls A, One WCS read and TP10C4 call G; type 1 (single nucleotide substitutions); mis-sense mutation at 15 in Tb927.1.1710 K -> E
WCS and TP1J20 call A, TP10C4 and TP8B6 call G; type 1 (single nucleotide substitutions); mis-sense mutation at 1227 in Tb927.1.1710 N -> D
WCS calls G, TP10C4 and TP8B6 call A; type 1 (single nucleotide substitutions); mis-sense mutation at 1694 in Tb927.1.1710 A -> T
WCS calls A, TP10C4 and TP27E7 call C; type 1 (single nucleotide substitutions); mis-sense mutation at 1749 in Tb927.1.1710 N -> T
WCS calls 11 T, TP10C4 and TP27E7 call 13 T; type 6 (insertion/deletion of 2 nucleotides)
Signal peptide predicted for Tb927.1.1720 by SignalP 2.0 HMM (Signal peptide probabilty 0.623, signal anchor probability 0.001) with cleavage site probability 0.403 between residues 30 and 31
Majority of WCS calls T, Two WCS reads, TP10C4 and TP27E7 call G; type 1 (single nucleotide substitutions); mis-sense mutation at 81 in Tb927.1.1720 V -> G
WCS calls C, TP10C4 calls T; type 1 (single nucleotide substitutions)
Majority of WCS calls G, One WCS read, TP8B6 and TP28N5 call A; type 1 (single nucleotide substitutions); mis-sense mutation at 6947 in Tb927.1.1740 V -> M
Deletion of ATATATATATATAT in TP10C4; type 5
Signal anchor predicted for Tb927.1.1760 by SignalP 2.0 HMM (Signal peptide probabilty 0.022, signal anchor probability 0.978) with cleavage site probability 0.012 between residues 45 and 46
3 probable transmembrane helices predicted for Tb927.1.1760 by TMHMM2.0 at aa 22-44, 54-76 and 88-110
Insertion of TT in one WCS read and TP10C4; type 6 (insertion/deletion of 2 nucleotides)
Majority of WCS calls T, One WCS read and TP10C4 call C; type 1 (single nucleotide substitutions); mis-sense mutation at 67 in Tb927.1.1760 F -> S
Majority of WCS calls 9 T, One WCS read and TP10C4 call 8 T; type 2 (single nucleotide insertions/deletions)
Signal anchor predicted for Tb927.1.1780 by SignalP 2.0 HMM (Signal peptide probabilty 0.382, signal anchor probability 0.601) with cleavage site probability 0.141 between residues 26 and 27
5 probable transmembrane helices predicted for Tb927.1.1780 by TMHMM2.0 at aa 4-26, 38-60, 64-86, 88-110 and 115-137
WCS calls T, TP10C4 calls C; type 1 (single nucleotide substitutions); mis-sense mutation at 44 in Tb927.1.1780 S -> P
Insertion of TGTGCATGTGTGTGTGTGTGTGTGTGTGTGTGTGTCTCTGTGTGTGTGCATGTGTGT GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG in one WCS read and TP10C4; type 5
Deletion of TATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTATTAT TATTATTATTAT in one WCS read and TP10C4; type 5
Majority of WCS calls C, One WCS read and TP10C4 call T; type 1 (single nucleotide substitutions); mis-sense mutation at 112 in Tb927.1.1780 S -> L
WCS calls G, TP8B6, TP28N5 and TP10C4 call C; type 1 (single nucleotide substitutions)
WCS calls 13 A, TP10C4 calls 12 A; type 2 (single nucleotide insertions/deletions)
1 probable transmembrane helix predicted for Tb927.1.1800 by TMHMM2.0 at aa 121-143
Insertion of ATATATATATATTTAT in TP10C4; type 5
Deletion of T in TP10C4 and TP8B6; type 2 (single nucleotide insertions/deletions)
Deletion of GTGAGTGA in one WCS read, TP10C4 and TP8B6; type 5
WCS calls TTTTTTTTCCCCC, TP10C4 calls TTTTTTTTTTCC with a 1 bp deletion; type 6 (insertion/deletion of 2 nucleotides)
Deletion of T in TP10C4; type 2 (single nucleotide insertions/deletions)
WCS calls TTTTTTTTT, TP10C4, TP28N5 and TP8B6 call TTTTTTTAA; type 6 (insertion/deletion of 2 nucleotides)
WCS calls T, TP10C4, TP28N5 and TP8B6 call C; type 1 (single nucleotide substitutions)
WCS and TP8B6 call 13 T, TP10C4 and TP28N5 call 14 T; type 2 (single nucleotide insertions/deletions)
WCS calls T, TP10C4, TP28N5 and TP8B6 call A; type 1 (single nucleotide substitutions)
WCS calls 12 T, TP10C4, TP28N5 and TP8B6 call 11 T; type 2 (single nucleotide insertions/deletions)
WCS calls A, TP10C4 and TP8B6 call G; type 1 (single nucleotide substitutions)
WCS calls A, TP8B6 calls T; type 1 (single nucleotide substitutions)
Majority of WCS calls G, One WCS read, TP10C4 and TP8B6 call A; type 1 (single nucleotide substitutions)
Insertion of TATATATTC in WCS read, TP10C4 and TP8B6; type 5
WCS calls T, TP10C4 and TP8B6 call C; type 1 (single nucleotide substitutions)
WCS calls 11 A, TP10C4 calls 10 A; type 2 (single nucleotide insertions/deletions)
WCS calls 5 G, TP10C4 calls 8 G; type 3 (insertion/deletion of 3 nucleotides)
Insertion of A in TP10C4; type 2 (single nucleotide insertions/deletions)
WCS calls G, TP10C4 calls A; type 1 (single nucleotide substitutions)
Insertion of TATATA in TP10C4 and TP8B6; type 5
WCS calls 9 T, TP10C4 calls 10 T; type 2 (single nucleotide insertions/deletions)
Insertion of TT in TP10C4; type 6 (insertion/deletion of 2 nucleotides)
WCS calls 7 A, TP10C4 calls 9 A; type 6 (insertion/deletion of 2 nucleotides)
WCS calls 11 A, TP10C4 and TP8B6 call 10 A; type 2 (single nucleotide insertions/deletions)
WCS calls 9 T, TP10C4 calls 11 T; type 6 (insertion/deletion of 2 nucleotides)
WCS calls C, TP10C4 and TP8B6 call T; type 1 (single nucleotide substitutions)
Deletion of CA in TP10C4 and TP8B6; type 5
WCS calls C, TP8B6 calls G; type 1 (single nucleotide substitutions)
WCS calls T, TP8B6 and TP28N5 call C; type 1 (single nucleotide substitutions)
WCS calls T, TP8B6 calls C; type 1 (single nucleotide substitutions)
Signal anchor predicted for Tb927.1.1860 by SignalP 2.0 HMM (Signal peptide probabilty 0.000, signal anchor probability 0.999) with cleavage site probability 0.000 between residues 33 and 34
2 probable transmembrane helices predicted for Tb927.1.1860 by TMHMM2.0 at aa 21-43 and 58-76
Majority of WCS and TP1O9 call 8 T, One WCS read and TP8B6 call 7 T; type 2 (single nucleotide insertions/deletions)
Insertion of TCC in one WCS read and TP8B6; type 3 (insertion/deletion of 3 nucleotides)
Signal peptide predicted for Tb927.1.1870 by SignalP 2.0 HMM (Signal peptide probabilty 0.986, signal anchor probability 0.000) with cleavage site probability 0.557 between residues 17 and 18
WCS calls A, TP8B6 calls G; type 1 (single nucleotide substitutions); mis-sense mutation at 87 in Tb927.1.1920 E -> G
Majority of WCS and TP1O9 call G, Two WCS reads call A; type 1 (single nucleotide substitutions); mis-sense mutation at 1002 in Tb927.1.1930 V -> M
Signal anchor predicted for Tb927.1.1950 by SignalP 2.0 HMM (Signal peptide probabilty 0.000, signal anchor probability 0.920) with cleavage site probability 0.000 between residues 29 and 30
1 probable transmembrane helix predicted for Tb927.1.1950 by TMHMM2.0 at aa 52-74
Signal anchor predicted for Tb927.1.1970 by SignalP 2.0 HMM (Signal peptide probabilty 0.091, signal anchor probability 0.873) with cleavage site probability 0.044 between residues 41 and 42
5 probable transmembrane helices predicted for Tb927.1.1980 by TMHMM2.0 at aa 147-169, 179-201, 208-230, 240-262 and 274-296
Signal peptide predicted for Tb927.1.2010 by SignalP 2.0 HMM (Signal peptide probabilty 0.906, signal anchor probability 0.000) with cleavage site probability 0.385 between residues 16 and 17
Signal peptide predicted for Tb927.1.2030 by SignalP 2.0 HMM (Signal peptide probabilty 0.878, signal anchor probability 0.000) with cleavage site probability 0.498 between residues 17 and 18
expression site-associated gene 2 (ESAG2) protein, putative
GPI-Anchor Signal predicted for Tb927.1.2040 by DGPI v2.04 with cleavage site probability 0.172 near 425
Signal peptide predicted for Tb927.1.2040 by SignalP 2.0 HMM (Signal peptide probabilty 1.000, signal anchor probability 0.000) with cleavage site probability 0.881 between residues 22 and 23
1 probable transmembrane helix predicted for Tb927.1.2050 by TMHMM2.0 at aa 82-104
Majority of WCS and TP1O9 call 9 C, Two WCS reads call 10 C; type 2 (single nucleotide insertions/deletions)
GPI-Anchor Signal predicted for Tb927.1.2090 by DGPI v2.04, no cleavage site predicted
2 probable transmembrane helices predicted for Tb927.1.2090 by TMHMM2.0 at aa 13-32 and 42-64
calpain-like cysteine peptidase; cysteine peptidase, Clan CA, family C2
calpain; cysteine peptidase, Clan CA, family C2
Majority of WCS and TP1O9 call A, One WCS read calls G; type 1 (single nucleotide substitutions)
GPI-Anchor Signal predicted for Tb927.1.2140 by DGPI v2.04, no cleavage site predicted
Signal anchor predicted for Tb927.1.2140 by SignalP 2.0 HMM (Signal peptide probabilty 0.192, signal anchor probability 0.770) with cleavage site probability 0.056 between residues 48 and 49
3 probable transmembrane helices predicted for Tb927.1.2140 by TMHMM2.0 at aa 10-32, 34-56 and 76-98
calpain-like protein fragment; calpain-like cysteine peptidase, Clan CA, family C2
Majority of WCS call T, One WCS read calls A; type 1 (single nucleotide substitutions)
4 probable transmembrane helices predicted for Tb927.1.2170 by TMHMM2.0 at aa 4-26, 31-50, 60-82 and 103-122
Deletion of TCTC in one WCS read; type 5
1 probable transmembrane helix predicted for Tb927.1.2180 by TMHMM2.0 at aa 113-135
Signal anchor predicted for Tb927.1.2180 by SignalP 2.0 HMM (Signal peptide probabilty 0.000, signal anchor probability 0.888) with cleavage site probability 0.000 between residues 63 and 64
Majority of WCS calls 10 A, One WCS read calls 11 A; type 2 (single nucleotide insertions/deletions)
WCS and TP29J12 call G, TP1O9 calls A; type 1 (single nucleotide substitutions)
Majority of WCS calls G, One WCS read calls T; type 1 (single nucleotide substitutions)
Majority of WCS calls C, One WCS read calls T; type 1 (single nucleotide substitutions); mis-sense mutation at 4 in Tb927.1.2210 P -> S
1 probable transmembrane helix predicted for Tb927.1.2220 by TMHMM2.0 at aa 36-58
similarity to calpain-like protein, but shorter (curated by J. Mottram)
3 probable transmembrane helices predicted for Tb927.1.2240 by TMHMM2.0 at aa 24-46, 51-73 and 75-97
2 probable transmembrane helices predicted for Tb927.1.2250 by TMHMM2.0 at aa 49-68 and 73-95
Majority of WCS calls 9 G, Two WCS reads call 8 G; type 2 (single nucleotide insertions/deletions)
Majority of WCS calls C, Two WCS reads call T; type 1 (single nucleotide substitutions)
Signal anchor predicted for Tb927.1.2280 by SignalP 2.0 HMM (Signal peptide probabilty 0.398, signal anchor probability 0.602) with cleavage site probability 0.203 between residues 20 and 21
3 probable transmembrane helices predicted for Tb927.1.2280 by TMHMM2.0 at aa 5-27, 47-69 and 74-96
Signal anchor predicted for Tb927.1.2290 by SignalP 2.0 HMM (Signal peptide probabilty 0.000, signal anchor probability 0.778) with cleavage site probability 0.000 between residues 20 and 21
1 probable transmembrane helix predicted for Tb927.1.2290 by TMHMM2.0 at aa 35-57
Signal peptide predicted for Tb927.1.2300 by SignalP 2.0 HMM (Signal peptide probabilty 0.999, signal anchor probability 0.001) with cleavage site probability 0.417 between residues 24 and 25
3 probable transmembrane helices predicted for Tb927.1.2300 by TMHMM2.0 at aa 7-26, 31-50 and 71-102
Signal anchor predicted for Tb927.1.2310 by SignalP 2.0 HMM (Signal peptide probabilty 0.000, signal anchor probability 1.000) with cleavage site probability 0.000 between residues 17 and 18
2 probable transmembrane helices predicted for Tb927.1.2310 by TMHMM2.0 at aa 7-29 and 39-61
len=3647 bp. Repeat unit from alpha and beta tubulin repeat array
RIME sequence at 3' end of Trypanosoma brucei tubulin cluster (EMBL:M27843) (1741 bp) Blastn scores: E()=e-119, id=99% (query, 1-226:subject, 34-259); RIME-A (DIRE). Degenerate (pers. comm. F. Bringaud)
Majority of WCS and TP1O9 call T, One WCS read, TP3D6 and TP29G13 call C; type 1 (single nucleotide substitutions)
Insertion of TA in one WCS read and TP3D6; type 6 (insertion/deletion of 2 nucleotides)
Insertion of TATATATATA in one WCS read,TP29G13 and TP3D6; type 5
WCS calls A, TP29G13 calls G; type 1 (single nucleotide substitutions)
WCS calls G, TP3D6 calls C; type 1 (single nucleotide substitutions)
WCS calls G, TP3D6 calls T; type 1 (single nucleotide substitutions)
WCS and TP1O9 call A, TP3D6 calls T; type 1 (single nucleotide substitutions)
RIME-A. Truncated (5') (pers. comm. F. Bringaud)
Majority of WCS and TP29J12 call A, One WCS read and TP3D6 call C; type 1 (single nucleotide substitutions)
Majority of WCS and TP29J12 call C, One WCS read and TP3D6 call A; type 1 (single nucleotide substitutions)
Majority of WCS and TP29J12 call G, One WCS read and TP3D6 call A; type 1 (single nucleotide substitutions)
len=1585 bp. Repeat unit for alternating histone H3 and hypothetical gene array
WCS calls A, TP3D6 and TP29G13 call G; type 1 (single nucleotide substitutions)
WCS calls G, TP3D6 and TP29G13 call A; type 1 (single nucleotide substitutions)
WCS calls G, TP3D6 and TP29G13 call C; type 1 (single nucleotide substitutions)
GPI-Anchor Signal predicted for Tb927.1.2440 by DGPI v2.04, no cleavage site predicted
Signal peptide predicted for Tb927.1.2440 by SignalP 2.0 HMM (Signal peptide probabilty 0.999, signal anchor probability 0.000) with cleavage site probability 0.540 between residues 20 and 21
GPI-Anchor Signal predicted for Tb927.1.2460 by DGPI v2.04, no cleavage site predicted
Signal peptide predicted for Tb927.1.2460 by SignalP 2.0 HMM (Signal peptide probabilty 0.999, signal anchor probability 0.000) with cleavage site probability 0.540 between residues 20 and 21
GPI-Anchor Signal predicted for Tb927.1.2480 by DGPI v2.04, no cleavage site predicted
Signal peptide predicted for Tb927.1.2480 by SignalP 2.0 HMM (Signal peptide probabilty 0.999, signal anchor probability 0.000) with cleavage site probability 0.540 between residues 20 and 21
GPI-Anchor Signal predicted for Tb927.1.2500 by DGPI v2.04, no cleavage site predicted
Signal peptide predicted for Tb927.1.2500 by SignalP 2.0 HMM (Signal peptide probabilty 0.999, signal anchor probability 0.000) with cleavage site probability 0.582 between residues 19 and 20
GPI-Anchor Signal predicted for Tb927.1.2520 by DGPI v2.04, no cleavage site predicted
Signal peptide predicted for Tb927.1.2520 by SignalP 2.0 HMM (Signal peptide probabilty 0.999, signal anchor probability 0.000) with cleavage site probability 0.582 between residues 19 and 20
GPI-Anchor Signal predicted for Tb927.1.2540 by DGPI v2.04, no cleavage site predicted
Signal peptide predicted for Tb927.1.2540 by SignalP 2.0 HMM (Signal peptide probabilty 0.999, signal anchor probability 0.000) with cleavage site probability 0.540 between residues 20 and 21
GPI-Anchor Signal predicted for Tb927.1.2560 by DGPI v2.04, no cleavage site predicted
Signal peptide predicted for Tb927.1.2560 by SignalP 2.0 HMM (Signal peptide probabilty 0.999, signal anchor probability 0.000) with cleavage site probability 0.540 between residues 20 and 21
Signal peptide predicted for Tb927.1.2570 by SignalP 2.0 HMM (Signal peptide probabilty 0.674, signal anchor probability 0.012) with cleavage site probability 0.551 between residues 22 and 23
WCS, TP1O9 and TP29J12 call C, TP29G13and TP3D6call T; type 1 (single nucleotide substitutions)
WCS and TP29J12 call A, TP29G13 and TP3D6 call G; type 1 (single nucleotide substitutions)
WCS and TP1O9 call A, TP3D6 calls G; type 1 (single nucleotide substitutions); mis-sense mutation at 505 in Tb927.1.2570 S -> G
Deletion of ATATATATATAT of TP29G13; type 5
Insertion of ATT in TP23G13 and TP3D6; type 5
RNasePH-like protein; exosome-associated protein 1; Rrp42 homologue
Majority of WCS calls A, Two WCS reads and TP29G13 call G; type 1 (single nucleotide substitutions)
Deletion of GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT in TP29G13; type 5
2 probable transmembrane helices predicted for Tb927.1.2590 by TMHMM2.0 at aa 7-29 and 44-66
Signal anchor predicted for Tb927.1.2590 by SignalP 2.0 HMM (Signal peptide probabilty 0.304, signal anchor probability 0.695) with cleavage site probability 0.198 between residues 33 and 34
WCS and TP1O9 call 10 T, TP3D6 and TP29G13 call 9 T; type 2 (single nucleotide insertions/deletions)
Majority of WCS reads call A, One WCS read and TP3D6 calls G; type 1 (single nucleotide substitutions)
GPI-Anchor Signal predicted for Tb927.1.2610 by DGPI v2.04 with cleavage site probability 0.74819994 near 17
Signal anchor predicted for Tb927.1.2610 by SignalP 2.0 HMM (Signal peptide probabilty 0.001, signal anchor probability 0.998) with cleavage site probability 0.001 between residues 34 and 35
1 probable transmembrane helix predicted for Tb927.1.2610 by TMHMM2.0 at aa 23-40
2 probable transmembrane helices predicted for Tb927.1.2620 by TMHMM2.0 at aa 29-51 and 55-77
WCS read calls A, TP3D6 calls G; type 1 (single nucleotide substitutions)
Signal anchor predicted for Tb927.1.2620 by SignalP 2.0 HMM (Signal peptide probabilty 0.004, signal anchor probability 0.996) with cleavage site probability 0.002 between residues 58 and 59
WCS calls 9 A, TP3D6 calls 8 A; type 2 (single nucleotide insertions/deletions)
Signal anchor predicted for Tb927.1.2630 by SignalP 2.0 HMM (Signal peptide probabilty 0.000, signal anchor probability 0.998) with cleavage site probability 0.000 between residues 62 and 63
2 probable transmembrane helices predicted for Tb927.1.2630 by TMHMM2.0 at aa 20-34 and 39-58
Majority of WCS and TP9H10 call G, One WCS read and TP3D6 calls T; type 1 (single nucleotide substitutions)
WCS and TP9H10 call 9 T, TP3D6 calls 10 T; type 2 (single nucleotide insertions/deletions)
Deletion of AAGAAAGA in TP3D6 and TP29G13; type 7
WCS and TP9H10 call C, TP3D6 and TP29G13 call G; type 1 (single nucleotide substitutions)
Deletion of GAAA in TP3D6 and TP29G13; type 4 (insertion/deletion of 4 or 5 nucleotides)
Insertion of CATATATA in TP29G13 and TP3D6; type 5
WCS calls T, TP29G13 and TP3D6 call C; type 1 (single nucleotide substitutions); mis-sense mutation at 40 in Tb927.1.2640 V -> A
Deletion of TTCAAAGTCAAA in TP3D6; type 5
2 probable transmembrane helices predicted for Tb927.1.2650 by TMHMM2.0 at aa 20-39 and 59-81
WCS calls C, TP29G13 calls T; type 1 (single nucleotide substitutions)
WCS calls 8 T, TP29G13 calls 9 T; type 2 (single nucleotide insertions/deletions)
WCS call T, TP29G13 calls A; type 1 (single nucleotide substitutions)
1 probable transmembrane helix predicted for Tb927.1.2660 by TMHMM2.0 at aa 20-54
WCS calls 11 T, TP29G13 calls 10 T; type 2 (single nucleotide insertions/deletions)
WCS and TP9H10 call 7 T, TP29G13 calls 6 T; type 2 (single nucleotide insertions/deletions)
WCS and TP9H10 call 10 A, TP29G13 calls 9 A; type 2 (single nucleotide insertions/deletions)
WCS and TP9H10 call 9 T, TP29G13 calls 10 T; type 2 (single nucleotide insertions/deletions)
axoneme central apparatus protein; importin alpha-1 subunit
WCS and TP9H10 call 11 A, TP3D6 calls 7 A; type 4 (insertion/deletion of 4 or 5 nucleotides)
2 probable transmembrane helices predicted for Tb927.1.2680 by TMHMM2.0 at aa 46-68 and 72-94
WCS and TP9H10 call 6 T, TP3D6 calls 7 T; type 2 (single nucleotide insertions/deletions)
WCS calls 13 A, TP3D6 calls 11 A; type 6 (insertion/deletion of 2 nucleotides)
WCS and TP9H10 call 12 A, TP3D6 calls 14 A; type 6 (insertion/deletion of 2 nucleotides)
WCS and TP9H10 call 8 G, TP3D6 and TP29G13 call 7 G; type 2 (single nucleotide insertions/deletions)
Deletion of GAAAA in TP3D6 and TP29G13; type 5
2 probable transmembrane helices predicted for Tb927.1.2690 by TMHMM2.0 at aa 70-92 and 118-135
Insertion of TATATATA in one WCS read, TP3D6 and TP29G13; type 5
WCS, TP26N22 and TP9H10 call 13 T, TP29G13 snd TP3D6 call 11 T; type 6 (insertion/deletion of 2 nucleotides)
Insertion of AT in one WCS read and TP3D6; type 5
WCS,TP9H10 and TP26N22 call G, One WCS read and TP3D6 call A; type 1 (single nucleotide substitutions)
WCS, TP9H10 and TP26N22 call A, TP23G13 and TP3D6 call G; type 1 (single nucleotide substitutions); mis-sense mutation at 365 in Tb927.1.2710 K -> R
WCS and TP26N22 call G, TP3D6 and TP29G13 call A; type 1 (single nucleotide substitutions)
Insertion of AGGAGG in TP3D6 and TP29G13; type 3 (insertion/deletion of 3 nucleotides)
WCS and TP26N22 call G, TP3D6 and TP29G13 call A; type 1 (single nucleotide substitutions); mis-sense mutation at 413 in Tb927.1.2710 E -> K
Majority of WCS and TP26N22 call C, One WCS read, TP29G13 and TP3D6 call T; type 1 (single nucleotide substitutions)
Majority of WCS and TP26N22 call T, One WCS read, TP29G13 and TP3D6 call G; type 1 (single nucleotide substitutions)
Signal anchor predicted for Tb927.1.2720 by SignalP 2.0 HMM (Signal peptide probabilty 0.001, signal anchor probability 0.997) with cleavage site probability 0.001 between residues 48 and 49
2 probable transmembrane helices predicted for Tb927.1.2720 by TMHMM2.0 at aa 15-37 and 44-66
Deletion of TTGTTG in one WCS read and TP29G13; type 5
WCS, TP9H10 and TP26N22 call 10 T, TP29G13 calls 13 T; type 6 (insertion/deletion of 2 nucleotides)
WCS, TP9H10 and TP26N22 call 10 T, TP3D6 and TP29G13 call 11 T; type 2 (single nucleotide insertions/deletions)
WCS, TP9H10 and TP26N22 call 9 T, TP3D6 and TP29G13 call 8 T; type 2 (single nucleotide insertions/deletions)
WCS, TP9H10 and TP26N22 call A, TP3D6 and TP29G13 call G; type 1 (single nucleotide substitutions)
Signal peptide predicted for Tb927.1.2730 by SignalP 2.0 HMM (Signal peptide probabilty 0.998, signal anchor probability 0.000) with cleavage site probability 0.219 between residues 44 and 45
Deletion of AAAAAGG in one WCS read, TP3D6 and TP29G13; type 5
Deletion of ATAAAA in TP3D6 and TP29G13; type 5
Signal peptide predicted for Tb927.1.2740 by SignalP 2.0 HMM (Signal peptide probabilty 0.796, signal anchor probability 0.038) with cleavage site probability 0.320 between residues 40 and 41
1 probable transmembrane helix predicted for Tb927.1.2740 by TMHMM2.0 at aa 58-80
WCS and TP26N22 call T, One WCS read and TP29G13 call C; type 1 (single nucleotide substitutions); mis-sense mutation at 470 in Tb927.1.2740 Y -> H
Majority of WCS call T, One WCS read, TP3D6 and TP29G13 call C; type 1 (single nucleotide substitutions)
WCS, TP9H10 and TP26N22 call T, TP29G13 calls C; type 1 (single nucleotide substitutions); mis-sense mutation at 88 in Tb927.1.2750 I -> T
WCS and TP26N22 call G, TP29G13 calls T; type 1 (single nucleotide substitutions); mis-sense mutation at 132 in Tb927.1.2750 V -> L
WCS and TP26N22 call 10 C, TP3D6 calls 11 C; type 2 (single nucleotide insertions/deletions)
Majority of WCS and TP26N22 call G, One WCS read and TP3D6 call A; type 1 (single nucleotide substitutions)
WCS, TP9H10 and TP26N22 call C, TP3D6 calls G; type 1 (single nucleotide substitutions); mis-sense mutation at 13 in Tb927.1.2780 R -> S
inverted repeat 1; hit to TBINGIC_3, RIME from M16068 copy A, 253bp 190..253 score: 239 percent id: 85.94; DIRE
WCS and TP9H10 call T, TP3D6 calls C; type 1 (single nucleotide substitutions)
WCS, TP9H10 and TP26N22 call C, One WCS read and TP29G13 call G; type 1 (single nucleotide substitutions)
WCS and TP9H10 call G, One WCS read, TP29G13 and TP3D6 call A; type 1 (single nucleotide substitutions)
inverted repeat 2; hit to TBINGIC_3, RIME from M16068 copy A, 253bp 190..253 score: 230 percent id: 84.38
Majority of WCS and TP9H10 call T, One WCS read, TP29G13 and TP3D6 call C; type 1 (single nucleotide substitutions)
WCS, TP9H10 and TP26N22 call G, TP3D6 and TP29G13 call C; type 1 (single nucleotide substitutions)
WCS, TP9H10 and TP26N22 call G, TP3D6 and TP29G13 call A; type 1 (single nucleotide substitutions)
Majority of WCS, TP9H10 and TP26N22 call G, One WCS read and TP3D6 call A; type 1 (single nucleotide substitutions)
Majority of WCS, TP9H10 and TP26N22 call G, One WCS read and TP3D6 call C; type 1 (single nucleotide substitutions); mis-sense mutation at 96 in Tb927.1.2820 T -> S
Majority of WCS, TP9H10 and TP26N22 call T, One WCS read and TP3D6 call C; type 1 (single nucleotide substitutions); mis-sense mutation at 96 in Tb927.1.2820 T -> A
Majority of WCS, TP9H10 and TP26N22 call C, One WCS read, TP3D6 and TP29G13 call T; type 1 (single nucleotide substitutions); mis-sense mutation at 80 in Tb927.1.2820 D -> N
Majority of WCS, TP9H10 and TP26N22 call A, One WCS read, TP3D6 and TP29G13 call G; type 1 (single nucleotide substitutions)
Majority of WCS, TP9H10 and TP26N22 call T, One WCS read, TP3D6 and TP29G13 call C; type 1 (single nucleotide substitutions); mis-sense mutation at 63 in Tb927.1.2820 K -> R
Majority of WCS and TP26N22 call G, One WCS read, TP3D6 and TP29G13 call A; type 1 (single nucleotide substitutions)
WCS and TP9H10 call A, TP29G13 calls G; type 1 (single nucleotide substitutions)
WCS and TP9H10 call C, TP29G13 calls T; type 1 (single nucleotide substitutions)
WCS and TP26N22 call G, TP29G13 and TP3D6 call A; type 1 (single nucleotide substitutions)
Majority of WCS and TP26N22 call T, Two WCS reads, TP3D6 and TP29G13 call C; type 1 (single nucleotide substitutions)
Majority of WCS and TP26N22 call G, Two WCS reads, TP3D6 and TP29G13 call A; type 1 (single nucleotide substitutions)
Signal peptide predicted for Tb927.1.2900 by SignalP 2.0 HMM (Signal peptide probabilty 0.916, signal anchor probability 0.009) with cleavage site probability 0.442 between residues 23 and 24
Majority of WCS call G, Three WCS reads call A; type 1 (single nucleotide substitutions)
Majority of WCS call G, One WCS calls A; type 1 (single nucleotide substitutions)
Majority of WCS and TP26N22 call 10 T, One WCS, TP3D6 and TP29G13 call 11 T; type 2 (single nucleotide substitutions)
Majority of WCS and TP26N22 call A, One WCS read, TP29G13 and TP3D6 call T; type 1 (single nucleotide substitutions)
Majority of WCS and TP26N22 call 9 T, One WCS read, TP3D6 and TP29G13 call 11 T; type 6 (insertion/deletion of 2 nucleotides)
WCS calls G, TP29G13 calls A; type 1 (single nucleotide substitutions)
Majority of WCS and TP26N22 call G, One WCS read and TP29G13 call C; type 1 (single nucleotide substitutions)
Signal peptide predicted for Tb927.1.2940 by SignalP 2.0 HMM (Signal peptide probabilty 0.712, signal anchor probability 0.003) with cleavage site probability 0.191 between residues 45 and 46
Majority of WCS call T, One WCS read and TP29G13 call C; type 1 (single nucleotide substitutions); mis-sense mutation at 91 in Tb927.1.2940 L -> S
Signal peptide predicted for Tb927.1.2950 by SignalP 2.0 HMM (Signal peptide probabilty 0.837, signal anchor probability 0.000) with cleavage site probability 0.153 between residues 34 and 35
WCS, TP9H10 and TP26N22 call A, TP29G13 calls G; type 1 (single nucleotide substitutions)
WCS, TP9H10 and TP26N22 call G, TP29G13 calls A; type 1 (single nucleotide substitutions)
Majority of WCS and TP26N22 call 12 T, Two WCS reads and TP29G13 calls 10 T; type 6 (insertion/deletion of 2 nucleotides)
WCS and TP26N22 call G, TP29G13 calls T; type 1 (single nucleotide substitutions)
WCS, TP9H10 and TP26N22 call 10 A, TP29G13 calls 9 A; type 2 (single nucleotide insertions/deletions)
WCS, TP9H10 and TP26N22 call A, TP29G13 calls C; type 1 (single nucleotide substitutions)
WCS and TP26N22 call G, TP29G13 calls A; type 1 (single nucleotide substitutions)
WCS and TP9H10 call G, TP29G13 calls A; type 1 (single nucleotide substitutions)
N-acyl-L-amino acid amidohydrolase, putative
GPI-Anchor Signal predicted for Tb927.1.3010 by DGPI v2.04, no cleavage site predicted
Signal peptide predicted for Tb927.1.3010 by SignalP 2.0 HMM (Signal peptide probabilty 0.691, signal anchor probability 0.030) with cleavage site probability 0.256 between residues 40 and 41
RNA editing ligase; RNA-editing complex protein; KREL2
WCS and TP9H10 call T, TP29G13 calls C; type 1 (single nucleotide substitutions); mis-sense mutation at 364 in Tb927.1.3030 V -> A
WCS, TP9H10 and TP26N22 call A, TP29G13 calls G; type 1 (single nucleotide substitutions); mis-sense mutation at 157 in Tb927.1.3040 H -> R
Signal peptide predicted for Tb927.1.3060 by SignalP 2.0 HMM (Signal peptide probabilty 0.977, signal anchor probability 0.000) with cleavage site probability 0.605 between residues 17 and 18
Signal anchor predicted for Tb927.1.3080 by SignalP 2.0 HMM (Signal peptide probabilty 0.000, signal anchor probability 0.807) with cleavage site probability 0.000 between residues 50 and 51
1 probable transmembrane helix predicted for Tb927.1.3080 by TMHMM2.0 at aa 37-59
WCS, TP9H10 and TP26N22 call 12 C, TP29G13 calls 11 C; type 2 (single nucleotide insertions/deletions)
GPI-Anchor Signal predicted for Tb927.1.3100 by DGPI v2.04 with cleavage site probability 0.49879998 near 50
Signal peptide predicted for Tb927.1.3100 by SignalP 2.0 HMM (Signal peptide probabilty 0.865, signal anchor probability 0.018) with cleavage site probability 0.204 between residues 28 and 29
1 probable transmembrane helix predicted for Tb927.1.3100 by TMHMM2.0 at aa 53-75
soluble N-ethylmaleimide sensitive factor (NSF) attachment protein, putative
separase; cysteine peptidase, Clan CD, family C50
WCS calls G, TP29G13 calls A; type 1 (single nucleotide substitutions); mis-sense mutation at 649 in Tb927.1.3120 R -> Q
WCS calls A, TP29G13 calls G; type 1 (single nucleotide substitutions); mis-sense mutation at 662 in Tb927.1.3120 K -> R
Majority of WCS and TP26N22 call C, One WCS read and TP29G13 call T; type 1 (single nucleotide substitutions); mis-sense mutation at 413 in Tb927.1.3130 P -> S
1 probable transmembrane helix predicted for Tb927.1.3140 by TMHMM2.0 at aa 29-51
Deletion of AT in one WCS read and TP29G13; type 5
Signal anchor predicted for Tb927.1.3150 by SignalP 2.0 HMM (Signal peptide probabilty 0.001, signal anchor probability 0.987) with cleavage site probability 0.000 between residues 43 and 44
4 probable transmembrane helices predicted for Tb927.1.3150 by TMHMM2.0 at aa 21-43, 112-131, 150-167 and 196-218
Signal peptide predicted for Tb927.1.3160 by SignalP 2.0 HMM (Signal peptide probabilty 0.695, signal anchor probability 0.004) with cleavage site probability 0.173 between residues 27 and 28
Majority of WCS, TP9H10 and TP26N22 call T, One WCS read and TP29G13 call C; type 1 (single nucleotide substitutions)
Majority of WCS,TP9H10 and TP26N22 call C, One WCS read and TP29G13 call G; type 1 (single nucleotide substitutions)
WCS, TP9H10 and TP26N22 call C, TP29G13 calls T; type 1 (single nucleotide substitutions)
WCS and TP9H10 call 14 A, TP29G13 calls 17 A; type 3 (insertion/deletion of 3 nucleotides)
Signal anchor predicted for Tb927.1.3190 by SignalP 2.0 HMM (Signal peptide probabilty 0.196, signal anchor probability 0.692) with cleavage site probability 0.104 between residues 21 and 22
1 probable transmembrane helix predicted for Tb927.1.3190 by TMHMM2.0 at aa 20-42
WCS and TP26N22 call C, TP29G13 calls T; type 1 (single nucleotide substitutions)
2 probable transmembrane helices predicted for Tb927.1.3210 by TMHMM2.0 at aa 48-70 and 85-107
Insertion of AT in one WCS read and TP29G13; type 5
GTPase activating protein of Rab-like GTPase, putative
Majority of WCS, TP9H10 and TP26N22 call G, Three WCS reads and TP29G13 call A; type 1 (single nucleotide substitutions)
1 probable transmembrane helix predicted for Tb927.1.3220 by TMHMM2.0 at aa 484-501
WCS and TP26N22 call A, TP29G13 calls G; type 1 (single nucleotide substitutions)
Signal peptide predicted for Tb927.1.3230 by SignalP 2.0 HMM (Signal peptide probabilty 0.748, signal anchor probability 0.002) with cleavage site probability 0.485 between residues 24 and 25
Signal peptide predicted for Tb927.1.3240 by SignalP 2.0 HMM (Signal peptide probabilty 0.948, signal anchor probability 0.042) with cleavage site probability 0.365 between residues 17 and 18
1 probable transmembrane helix predicted for Tb927.1.3240 by TMHMM2.0 at aa 2-24
WCS and TP26N22 call 9 T, TP29G13 calls 10 T; type 2 (single nucleotide insertions/deletions)
Majority of WCS and TP26N22 call A, Three WCS reads and TP29G13 call G; type 1 (single nucleotide substitutions); mis-sense mutation at 504 in Tb927.1.3250 Q -> R
WCS and TP26N22 call G, TP29G13 calls A; type 1 (single nucleotide substitutions); mis-sense mutation at 1642 in Tb927.1.3250 A -> T
WCS and TP26N22 call T, TP29G13 calls C; type 1 (single nucleotide substitutions)
WCS and TP26N22 call G, TP29G13 calls A; type 1 (single nucleotide substitutions); mis-sense mutation at 828 in Tb927.1.3260 G -> E
Majority of WCS call C, One WCS read calls T; type 1 (single nucleotide substitutions); mis-sense mutation at 1762 in Tb927.1.3260 A -> V
septum formation protein MAF homologue, putative
Majority of WCS, TP25P16 and TP26N22 call G, Two WCS reads call A; type 1 (single nucleotide substitutions); mis-sense mutation at 27 in Tb927.1.3320 G -> S
Majority of WCS, TP25P16 and TP26N22 call A, Two WCS reads call G; type 1 (single nucleotide substitutions)
Majority of WCS and TP26N22 call C, One WCS read calls G; type 1 (single nucleotide substitutions)
Majority of WCS, TP25P16 and TP26N22 call T, Two WCS reads call C; type 1 (single nucleotide substitutions); mis-sense mutation at 71 in Tb927.1.3370 R -> G
Signal peptide predicted for Tb927.1.3370 by SignalP 2.0 HMM (Signal peptide probabilty 0.947, signal anchor probability 0.010) with cleavage site probability 0.359 between residues 15 and 16
Signal peptide predicted for Tb927.1.3380 by SignalP 2.0 HMM (Signal peptide probabilty 0.968, signal anchor probability 0.000) with cleavage site probability 0.578 between residues 33 and 34
GPI-Anchor Signal predicted for Tb927.1.3400 by DGPI v2.04, no cleavage site predicted
Signal anchor predicted for Tb927.1.3410 by SignalP 2.0 HMM (Signal peptide probabilty 0.279, signal anchor probability 0.720) with cleavage site probability 0.193 between residues 58 and 59
2 probable transmembrane helices predicted for Tb927.1.3410 by TMHMM2.0 at aa 13-35 and 39-56
1 probable transmembrane helix predicted for Tb927.1.3420 by TMHMM2.0 at aa 21-43
2 probable transmembrane helices predicted for Tb927.1.3440 by TMHMM2.0 at aa 12-34 and 44-66
2 probable transmembrane helices predicted for Tb927.1.3460 by TMHMM2.0 at aa 62-84 and 111-133
Deletion of TTTCTTTC in three WCS reads; type 5
Deletion of TTTTTTTT in three WCS reads; type 6 (insertion/deletion of 6 or more nucleotides)
Majority of WCS and TP26N22 call A, Two WCS reads call C; type 1 (single nucleotide substitutions)
Majority of WCS and TP26N22 call G, Two WCS call A; type 1 (single nucleotide substitutions)
Majority of WCS call G, Two WCS reads call C; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call T, Two WCS reads call C; type 1 (single nucleotide substitutions)
Majority of WCS, TP25P16 and TP26N22 call A, One WCS read calls C; type 1 (single nucleotide substitutions)
2 probable transmembrane helices predicted for Tb927.1.3480 by TMHMM2.0 at aa 10-32 and 89-111
Signal anchor predicted for Tb927.1.3480 by SignalP 2.0 HMM (Signal peptide probabilty 0.148, signal anchor probability 0.830) with cleavage site probability 0.085 between residues 34 and 35
1 probable transmembrane helix predicted for Tb927.1.3530 by TMHMM2.0 at aa 71-93
2 probable transmembrane helices predicted for Tb927.1.3540 by TMHMM2.0 at aa 15-37 and 56-78
Signal anchor predicted for Tb927.1.3540 by SignalP 2.0 HMM (Signal peptide probabilty 0.001, signal anchor probability 0.709) with cleavage site probability 0.000 between residues 44 and 45
Majority of WCS and TP25P16 call A, One WCS read calls T; type 1 (single nucleotide substitutions)
2 probable transmembrane helices predicted for Tb927.1.3570 by TMHMM2.0 at aa 21-43 and 73-95
GPI-Anchor Signal predicted for Tb927.1.3590 by DGPI v2.04 with cleavage site probability 0.12900001 near 79
3 probable transmembrane helices predicted for Tb927.1.3610 by TMHMM2.0 at aa 68-90, 144-166 and 171-188
RIME-A; similar to RIME from Trypanosoma brucei DNA for trypanosome repeated sequence TRS 1.6 (EMBL:X05710) (6826 bp); Blastn score=527, E()=e-147, id=96% (query, 5-314:subject, 714-1023)
ingi; Similar to Trypanosoma brucei DNA for trypanosome repeated sequence TRS 1.6 (EMBL:X05710) (6826 bp); Blastn score=6611 E()=0.0, id=96%; ingi - one point mutation (pers. comm. F. Bringaud)
expression site-associated gene (ESAG) protein; expression site-associated gene 8 (ESAG8)
Deletion of G in one WCS read; type 2 (single nucleotide insertions/deletions)
RIME-A (ingi); similar to Trypanosoma brucei ribosomal mobile element (RIME) in rRNA gene (EMBL:K01801) (1402 bp); Blastn score=389, E()=e-106, Id=95%
ingi; Similar to T. brucei repetitive element ingi3 EMBL:M16068 (5204 bp); Blastn score=4278, E()=0.0, Id=95%; several point mutations (pers. comm. F. Bringaud)
RIME-B (ingi); similar to Trypanosoma brucei ribosomal mobile element (RIME) in rRNA (EMBL:K01801) (1402 bp); Blastn score=331, E()=1e-88, Id=93%
3 probable transmembrane helices predicted for Tb927.1.3700 by TMHMM2.0 at aa 5-27, 34-53 and 63-80
Signal peptide predicted for Tb927.1.3720 by SignalP 2.0 HMM (Signal peptide probabilty 0.603, signal anchor probability 0.000) with cleavage site probability 0.217 between residues 30 and 31
Majority of WCS call T, One WCS read calls C; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call C, Four WCS reads call T; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call C, Four WCS reads call A; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call A, Four WCS reads call C; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call A, Four WCS reads call G; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call T, Four WCS reads call C; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call T, Four WCS reads call A; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call G, Two WCS reads call A; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call T, Two WCS reads call G; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call A, Two WCS reads call G; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call A, Four WCS reads and TP18B5 call G; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call G, Nine WCS reads and TP18B5 call A; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call C, Nine WCS reads call T; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call G, One WCS read calls A; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call C, One WCS read calls A; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call A, One WCS read calls C; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call A, One WCS read calls G; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call A, Three WCS reads call G; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call C, Three WCS reads call T; type 1 (single nucleotide substitutions)
rRNA M1/220 small ribosomal RNA /small ribosomal RNA 1
Majority of WCS call G, One WCS read calls A; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call T, One WCS read calls C; type 1 (single nucleotide substitutions)
GPI-Anchor Signal predicted for Tb927.1.3740 by DGPI v2.04, no cleavage site predicted
Insertion of AT in one WCS read; type 6 (insertion/deletion of 2 nucleotides)
Majority of WCS and TP25P16 call 7 A, One WCS read calls 8 A; type 2 (single nucleotide insertions/deletions)
1 probable transmembrane helix predicted for Tb927.1.3740 by TMHMM2.0 at aa 91-110
Majority of WCS and TP25P16 call 5 T, One WCS read calls 6 T; type 2 (single nucleotide insertions/deletions)
Deletion of TC in four WCS reads; type 5
Majority of WCS and TP25P16 call G, Four WCS reads call A; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call A, Four WCS reads call T; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call C, Four WCS reads call G; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call C, One WCS read calls T; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call T, One WCS read calls G; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call A, One WCS read calls G; type 1 (single nucleotide substitutions); mis-sense mutation at 135 in Tb927.1.3750 Y -> H
Majority of WCS and TP25P16 call T, One WCS read calls C; type 1 (single nucleotide substitutions); mis-sense mutation at 75 in Tb927.1.3750 T -> A
Majority of WCS and TP25P16 call A, One WCS read calls G; type 1 (single nucleotide substitutions); mis-sense mutation at 14 in Tb927.1.3750 V -> A
Majority of WCS and TP25P16 call A, Three WCS reads call C; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call C, Three WCS reads call A; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call T, Three WCS reads call G; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call T, One WCS read calls G; type 1 (single nucleotide substitutions); mis-sense mutation at 169 in Tb927.1.3760 K -> Q
Majority of WCS and TP25P16 call A, Three WCS reads call G; type 1 (single nucleotide substitutions); mis-sense mutation at 158 in Tb927.1.3760 F -> L
Majority of WCS and TP25P16 call T, Three WCS reads call C; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call T, One WCS read calls G; type 1 (single nucleotide substitutions); mis-sense mutation at 129 in Tb927.1.3760 E -> A
RIME; Similar to Trypanosoma brucei ribosomal mobile element (RIME) in rRNA gene (EMBL:K01801) (1402 bp); Blastn score=256, E()=5e-66, Id=90%
Majority of WCS and TP25P16 call G, Two WCS reads call T; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call G, Two WCS call A; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call A, Two WCS reads call C; type 1 (single nucleotide substitutions)
Majority of WCS and TP25P16 call C, Two WCS reads call T; type 1 (single nucleotide substitutions)
Signal peptide predicted for Tb927.1.3790 by SignalP 2.0 HMM (Signal peptide probabilty 0.984, signal anchor probability 0.001) with cleavage site probability 0.240 between residues 14 and 15
GPI-Anchor Signal predicted for Tb927.1.3790 by DGPI v2.04 with cleavage site probability 0.516 near 125
Signal peptide predicted for Tb927.1.3810 by SignalP 2.0 HMM (Signal peptide probabilty 0.958, signal anchor probability 0.024) with cleavage site probability 0.600 between residues 25 and 26
1 probable transmembrane helix predicted for Tb927.1.3810 by TMHMM2.0 at aa 9-28
glucose-6-phosphate isomerase, glycosomal
WCS, TP25P16 and TP25O14 call A, TP18B5 calls T; type 1 (single nucleotide substitutions)
Signal anchor predicted for Tb927.1.3840 by SignalP 2.0 HMM (Signal peptide probabilty 0.254, signal anchor probability 0.618) with cleavage site probability 0.062 between residues 34 and 35
1 probable transmembrane helix predicted for Tb927.1.3840 by TMHMM2.0 at aa 20-37
WCS and TP25O14 call 8 T, TP18B5 calls 10 T; type 6 (insertion/deletion of 2 nucleotides)
GPI-Anchor Signal predicted for Tb927.1.3850 by DGPI v2.04, no cleavage site predicted
Signal anchor predicted for Tb927.1.3850 by SignalP 2.0 HMM (Signal peptide probabilty 0.000, signal anchor probability 0.967) with cleavage site probability 0.000 between residues 42 and 43
1 probable transmembrane helix predicted for Tb927.1.3850 by TMHMM2.0 at aa 23-45
Majority of WCS and TP25P16 call G, Four WCS reads call A; type 1 (single nucleotide substitutions); mis-sense mutation at 261 in Tb927.1.3860 V -> I
Majority of WCS call T, Three WCS reads and TP18B5 call C; type 1 (single nucleotide substitutions)
Deletion of GG in TP18B5; type 6 (insertion/deletion of 2 nucleotides)
WCS and TP25P16 call G, TP18B5 calls T; type 1 (single nucleotide substitutions)
GPI-Anchor Signal predicted for Tb927.1.3870 by DGPI v2.04, no cleavage site predicted
Signal anchor predicted for Tb927.1.3870 by SignalP 2.0 HMM (Signal peptide probabilty 0.199, signal anchor probability 0.710) with cleavage site probability 0.069 between residues 34 and 35
1 probable transmembrane helix predicted for Tb927.1.3870 by TMHMM2.0 at aa 21-43
WCS, TP25P16 and TP28D20 call T, TP18B5 calls A; type 1 (single nucleotide substitutions); mis-sense mutation at 1317 in Tb927.1.3880 F -> Y
WCS, TP25P16 and TP28D20 call G, TP18B5 calls C; type 1 (single nucleotide substitutions); mis-sense mutation at 1597 in Tb927.1.3880 G -> A
WCS, TP25P16, TP28D20 and TP25O14 call G, TP18B5 calls A; type 1 (single nucleotide substitutions); mis-sense mutation at 1651 in Tb927.1.3880 A -> T
WCS, TP25P16, TP28D20 and TP25O14 call T, TP18B5 calls C; type 1 (single nucleotide substitutions)
WCS, TP25P16 and TP28D20 call G, TP18B5 calls T; type 1 (single nucleotide substitutions)
WCS and TP25P16 call 10 G, TP18B5 calls 9 G; type 2 (single nucleotide insertions/deletions)
Majority of WCS and TP25P16 call 9 T, Two WCS read and TP18B5 call 10 T; type 2 (single nucleotide insertions/deletions)
Majority of WCS and TP25P16 call C, One WCS read and TP18B5 call T; type 1 (single nucleotide substitutions)
1 probable transmembrane helix predicted for Tb927.1.3900 by TMHMM2.0 at aa 4-21
Majority of WCS, TP25P16 and TP28D20 call 10 G, One WCS read and TP18B5 call 9 G; type 2 (single nucleotide insertions/deletions)
Insertion of TATA in TP18B5, TP28P1 and one wcs read; type 5
1 probable transmembrane helix predicted for Tb927.1.3920 by TMHMM2.0 at aa 57-79
GPI-Anchor Signal predicted for Tb927.1.3930 by DGPI v2.04, no cleavage site predicted
1 probable transmembrane helix predicted for Tb927.1.3930 by TMHMM2.0 at aa 5-27
WCS, TP18B5, TP28D20, TP28P1 and TP1H9 call 11 T, TP25O14 calls 12 T; type 2 (single nucleotide insertions/deletions)
WCS and TP25O14 call T, TP28P1 and TP18B5 call C; type 1 (single nucleotide substitutions)
Majority of WCS and TP1H9 call G, TP28P1, TP18B5 and one WCS read call T; type 1 (single nucleotide substitutions); mis-sense mutation at 168 in Tb927.1.3940 V -> L
Majority of WCS, TP25O14 and TP28D20 call A, One WCS read, TP18B5 and TP28P1 call G; type 1 (single nucleotide substitutions); mis-sense mutation at 842 in Tb927.1.3940 S -> G
WCS, TP1H9 and TP28D20 call 13 A, TP18B5 calls 12 A; type 2 (single nucleotide insertions/deletions)
Signal anchor predicted for Tb927.1.3970 by SignalP 2.0 HMM (Signal peptide probabilty 0.047, signal anchor probability 0.833) with cleavage site probability 0.025 between residues 36 and 37
1 probable transmembrane helix predicted for Tb927.1.3970 by TMHMM2.0 at aa 21-43
Deletion of TACTAT in TP18B5 and TP28P1; type 5
WCS and TP28D20 call A, TP18B5 and TP28P1 call G; type 1 (single nucleotide substitutions)
Deletion of ATATAT in TP18B5 and TP28P1; type 5
Signal anchor predicted for Tb927.1.4000 by SignalP 2.0 HMM (Signal peptide probabilty 0.068, signal anchor probability 0.923) with cleavage site probability 0.016 between residues 26 and 27
3 probable transmembrane helices predicted for Tb927.1.4000 by TMHMM2.0 at aa 4-23, 30-52 and 62-84
Insertion of ACTTTTTCTCTC in TP18B5, TP28P1 and one WCS read; type 5
Deletion of TATA in TP18B5 and TP28P1; type 5
Majority of WCS and TP28D20 call G, One WCS read, TP28P1 and TP18B5 call A; type 1 (single nucleotide substitutions)
Majority of WCS and TP28D20 call A, One WCS read, TP18B5 and TP28P1 call G; type 1 (single nucleotide substitutions)
Signal peptide predicted for Tb927.1.4010 by SignalP 2.0 HMM (Signal peptide probabilty 0.885, signal anchor probability 0.001) with cleavage site probability 0.274 between residues 22 and 23
Majority of WCS and TP28D20 call T, One WCS read, TP18B5 and TP28P1 call C; type 1 (single nucleotide substitutions)
Majority of WCS and TP28D20 call 11 T, One WCS read, TP18B5 and TP28P1 call 10 T; type 2 (single nucleotide insertions/deletions)
GPI-Anchor Signal predicted for Tb927.1.4020 by DGPI v2.04, no cleavage site predicted
Signal anchor predicted for Tb927.1.4020 by SignalP 2.0 HMM (Signal peptide probabilty 0.333, signal anchor probability 0.666) with cleavage site probability 0.063 between residues 35 and 36
5 probable transmembrane helices predicted for Tb927.1.4020 by TMHMM2.0 at aa 20-39, 59-81, 90-112, 127-144 and 151-173
WCS and TP28D20 call 11 A, TP18B5 calls 12 A; type 2 (single nucleotide insertions/deletions)
Deletion of TATT in one WCS read and TP18B5; type 5
Majority of WCS call 14 T, One WCS read, TP18B5 and TP28P1 call 13 T; type 2 (single nucleotide insertions/deletions)
Signal anchor predicted for Tb927.1.4030 by SignalP 2.0 HMM (Signal peptide probabilty 0.195, signal anchor probability 0.804) with cleavage site probability 0.106 between residues 21 and 22
3 probable transmembrane helices predicted for Tb927.1.4030 by TMHMM2.0 at aa 4-26, 46-68 and 83-105
Majority of WCS, TP28D20 and TP25O14 call 10 A, One WCS read and TP18B5 call 11 T; type 2 (single nucleotide insertions/deletions)
Deletion of AGAG in one WCS read and TP18B5; type 5
Majority of WCS and TP28D20 call 9 A, One WCS read and TP18B5 call 10 A; type 2 (single nucleotide insertions/deletions)
Majority of WCS call 12 T, One WCS read, TP28P1 and TP18B5 call 11 T; type 2 (single nucleotide insertions/deletions)
WCS, TP28D20 and TP1H9 call C, TP18B5 calls T; type 1 (single nucleotide substitutions)
WCS, TP28D20 and TP1H9 call A, TP18B5 calls G; type 1 (single nucleotide substitutions)
WCS, TP28D20 and TP1H9 call 6 T, TP18B5 call 5 T; type 2 (single nucleotide insertions/deletions)
WCS callS T, TP18B5 calls A; type 1 (single nucleotide substitutions)
WCS callS T, TP18B5 calls C; type 1 (single nucleotide substitutions)
WCS calls 12 T, TP18B5 calls 10 T; type 6 (insertion/deletion of 2 nucleotides)
WCS calls A, TP18B5 calls G; type 1 (single nucleotide substitutions)
Insertion of ATATATATATATATATATATATATAT in TP18B5; type 5
WCS, TP28D20 and TP1H9 call G, TP18B5 calls A; type 1 (single nucleotide substitutions)
Deletion of AAA in TP18B5; type 3 (insertion/deletion of 3 nucleotides)
WCS and TP1H9 call C, TP18B5 calls T; type 1 (single nucleotide substitutions)
WCS and TP1H9 call T, TP18B5 calls C; type 1 (single nucleotide substitutions)
Majority of WCS and TP28D20 call A, Two WCS reads and TP18B5 call G; type 1 (single nucleotide substitutions); mis-sense mutation at 795 in Tb927.1.4050 N -> S
Deletion of TA in one WCS read and TP18B5; type 5
1 probable transmembrane helix predicted for Tb927.1.4060 by TMHMM2.0 at aa 72-94
Insertion of TATATA in one WCS read and TP18B5; type 5
WCS and TP28D20 call G, One WCS read and TP18B5 call A; type 1 (single nucleotide substitutions)
1 probable transmembrane helix predicted for Tb927.1.4070 by TMHMM2.0 at aa 10-32
Deletion of GT in two WCS reads and TP18B5; type 5
Majority of WCS and TP28D20 call T, One WCS read and TP18B5 call G; type 1 (single nucleotide substitutions)
WCS calls T, TP18B5 and TP28P1 call C; type 1 (single nucleotide substitutions)
Insertion of ATAT in one WCS read and TP18B5; type 5
Majority of WCS reads call C, One WCS read and TP18B5 call T; type 1 (single nucleotide substitutions)
Majority of WCS reads call 10 T, One WCS read and TP18B5 call 9 T; type 2 (single nucleotide insertions/deletions)
cytochrome C oxidase subunit IV (PMID:12467979)
Signal peptide predicted for Tb927.1.4100 by SignalP 2.0 HMM (Signal peptide probabilty 0.996, signal anchor probability 0.000) with cleavage site probability 0.356 between residues 23 and 24
Majority of WCS reads,TP1H9 and TP28D20 call G, Two WCS reads and TP18B5 call A; type 1 (single nucleotide substitutions)
Majority of WCS and TP18D20 call A, Two WCS reads, TP28P1 and TP18B5 call G; type 1 (single nucleotide substitutions); mis-sense mutation at 262 in Tb927.1.4100 T -> A
WCS and TP28D20 call T, TP18B5 calls C; type 1 (single nucleotide substitutions)
unlikely gene predicted by glimmer; low complexity composition
1 probable transmembrane helix predicted for Tb927.1.4120 by TMHMM2.0 at aa 7-26
WCS calls C, TP18B5 calls T; type 1 (single nucleotide substitutions)
Majority of WCS and TP1H9 call A, One WCS read and TP18B5 call G; type 1 (single nucleotide substitutions)
Majority of WCS and TP1H9 call T, One WCS read and TP18B5 call C; type 1 (single nucleotide substitutions)
Signal anchor predicted for Tb927.1.4130 by SignalP 2.0 HMM (Signal peptide probabilty 0.172, signal anchor probability 0.828) with cleavage site probability 0.084 between residues 46 and 47
3 probable transmembrane helices predicted for Tb927.1.4130 by TMHMM2.0 at aa 7-26, 36-58 and 79-101
Majority of WCS call A, One WCS read, TP18B5 and TP28P1 call G; type 1 (single nucleotide substitutions); mis-sense mutation at 272 in Tb927.1.4140 T -> A
Majority of WCS calls G, One WCS read, TP18B5 and TP28P1 call A; type 1 (single nucleotide substitutions)
Majority of WCS calls 13 T, One WCS read, TP18B5 and TP28P1 call 11 T; type 6 (insertion/deletion of 2 nucleotides)
Insertion of ACACACAC in one WCS read, TP18B5 and TP28P1; type 5
Insertion of CATT in one WCS read, TP18B5 and TP28P1; type 4 (insertion/deletion of 4 or 5 nucleotides)
GPI-Anchor Signal predicted for Tb927.1.4150 by DGPI v2.04 with cleavage site probability 0.124699995 near 70
Signal anchor predicted for Tb927.1.4150 by SignalP 2.0 HMM (Signal peptide probabilty 0.015, signal anchor probability 0.977) with cleavage site probability 0.007 between residues 29 and 30
3 probable transmembrane helices predicted for Tb927.1.4150 by TMHMM2.0 at aa 15-37, 57-74 and 89-106
WCS and TP1H9 call A, TP18B5 and TP28P1 call C; type 1 (single nucleotide substitutions)
Deletion of TT in TP18B5 and TP28P1; type 6 (insertion/deletion of 2 nucleotides)
Majority of WCS and TP1H9 call A, One WCS read, TP18B5 and TP28P1 call G; type 1 (single nucleotide substitutions)
Signal anchor predicted for Tb927.1.4160 by SignalP 2.0 HMM (Signal peptide probabilty 0.221, signal anchor probability 0.759) with cleavage site probability 0.074 between residues 24 and 25
1 probable transmembrane helix predicted for Tb927.1.4160 by TMHMM2.0 at aa 13-30
One WCS read and TP1H9 call 11 G, Two WCS reads and TP28P1 call 8 G; type 3 (insertion/deletion of 3 nucleotides)
1 probable transmembrane helix predicted for Tb927.1.4170 by TMHMM2.0 at aa 21-43
Majority of WCS and TP1H9 call T, Two WCS reads and TP28P1 call G; type 1 (single nucleotide substitutions)
Majority of WCS and TP1H9 call G, Two WCS reads and TP28P1 call A; type 1 (single nucleotide substitutions)
Insertion of TATATATATATTTCTATA in two WCS reads and TP28P1; type 5
WCS, TP1H9 and TP28D20 call C, TP28P1 calls T; type 1 (single nucleotide substitutions)
Signal peptide predicted for Tb927.1.4190 by SignalP 2.0 HMM (Signal peptide probabilty 0.979, signal anchor probability 0.018) with cleavage site probability 0.549 between residues 22 and 23
1 probable transmembrane helix predicted for Tb927.1.4190 by TMHMM2.0 at aa 5-27
WCS and TP28D20 call T, TP28P1 calls C; type 1 (single nucleotide substitutions)
WCS and TP28D20 call A, TP28P1 calls G; type 1 (single nucleotide substitutions)
WCS and TP28D20 call G, TP28P1 calls A; type 1 (single nucleotide substitutions)
Signal anchor predicted for Tb927.1.4200 by SignalP 2.0 HMM (Signal peptide probabilty 0.061, signal anchor probability 0.881) with cleavage site probability 0.050 between residues 44 and 45
WCS and TP28D20 call C, TP28P1 calls T; type 1 (single nucleotide substitutions)
1 probable transmembrane helix predicted for Tb927.1.4200 by TMHMM2.0 at aa 24-46
GPI-Anchor Signal predicted for Tb927.1.4210 by DGPI v2.04 with cleavage site probability 0.103199996 near 43
1 probable transmembrane helix predicted for Tb927.1.4210 by TMHMM2.0 at aa 36-58
Majority of WCS, TP28D20 and TP1H9 call C, One WCS read calls T; type 1 (single nucleotide substitutions)
GPI-Anchor Signal predicted for Tb927.1.4220 by DGPI v2.04 with cleavage site probability 0.72 near 401
Signal peptide predicted for Tb927.1.4220 by SignalP 2.0 HMM (Signal peptide probabilty 0.981, signal anchor probability 0.010) with cleavage site probability 0.523 between residues 28 and 29
Majority of WCS and TP28D20 call T, One WCS read and TP28P1 call C; type 1 (single nucleotide substitutions)
Majority of WCS and TP28D20 call G, One WCS read and TP28P1 call A; type 1 (single nucleotide substitutions)
WCS calls A, TP28P1 calls G; type 1 (single nucleotide substitutions); mis-sense mutation at 513 in Tb927.1.4250 I -> V
WCS calls C, TP28P1 calls T; type 1 (single nucleotide substitutions); mis-sense mutation at 620 in Tb927.1.4250 H -> Y
WCS calls 10 T, TP28P1 calls 11 T; type 2 (single nucleotide insertions/deletions)
Majority of WCS calls G, One WCS read and TP28P1 call A; type 1 (single nucleotide substitutions)
WCS calls G, TP28P1 calls A; type 1 (single nucleotide substitutions)
WCS and TP28D20 call 14 T, TP28P1 calls 11 T; type 3 (insertion/deletion of 3 nucleotides)
WCS calls G, TP28P1 calls T; type 1 (single nucleotide substitutions)
WCS and TP1H9 call 7 A, TP28P1 calls 8 A; type 2 (single nucleotide insertions/deletions)
WCS and TP1H9 call C, TP28P1 calls A; type 1 (single nucleotide substitutions)
WCS and TP1H9 call G, TP28P1 calls A; type 1 (single nucleotide substitutions)
WCS and TP1H9 call A, TP28P1 calls G; type 1 (single nucleotide substitutions)
WCS, TP28D20 and TP1H9 call 10 T, TP28P1 calls 9 T; type 2 (single nucleotide insertions/deletions)
WCS, TP28D20 and TP1H9 call T, TP28P1 calls C; type 1 (single nucleotide substitutions)
Majority of WCS, TP28D20 and TP1H9 call 9 T, One WCS read and TP28P1 call 7 T; type 6 (insertion/deletion of 2 nucleotides)
Deletion of TCTC in one WCS read and TP28P1; type 5
Deletion of TA in one WCS read and TP28P1; type 6 (insertion/deletion of 2 nucleotides)
Majority of WCS call 14 A, One WCS read and TP28P1 call 11 A; type 3 (insertion/deletion of 3 nucleotides)
WCS call CCAAAAAAAAAAT, One WCS read and TP28P1 call CAAAAAAAAAAAAAT; type 6 (insertion/deletion of 2 nucleotides)
WCS callS T, TP28P1 calls C; type 1 (single nucleotide substitutions)
Signal anchor predicted for Tb927.1.4290 by SignalP 2.0 HMM (Signal peptide probabilty 0.006, signal anchor probability 0.990) with cleavage site probability 0.004 between residues 23 and 24
2 probable transmembrane helices predicted for Tb927.1.4290 by TMHMM2.0 at aa 5-27 and 42-64
WCS callS C, TP28P1 calls G; type 1 (single nucleotide substitutions); mis-sense mutation at 18 in Tb927.1.4290 L -> V
WCS and TP28D20 call C, TP28P1 calls T; type 1 (single nucleotide substitutions); mis-sense mutation at 28 in Tb927.1.4290 S -> F
WCS and TP28D20 call C, TP28P1 calls G; type 1 (single nucleotide substitutions); mis-sense mutation at 32 in Tb927.1.4290 L -> V
Deletion of TG in TP28P1; type 6 (insertion/deletion of 2 nucleotides)
WCS and TP28D20 call C, TP28P1 calls T; type 1 (single nucleotide substitutions); mis-sense mutation at 35 in Tb927.1.4290 H -> Y
One WCS read, TP19A1 and TP1C9 call T, One WCS read and TP28P1 call G; type 1 (single nucleotide substitutions)
One WCS read, TP19A1 and TP1C9 call G, One WCS read and TP28P1 call A; type 1 (single nucleotide substitutions)
Insertion of CTTT in one WCS read and TP28P1; type 4 (insertion/deletion of 4 or 5 nucleotides)
Majority of WCS reads and TP1H9 call A, One WCS read and TP28P1 call G; type 1 (single nucleotide substitutions); mis-sense mutation at 1474 in Tb927.1.4310 T -> A
Insertion of TATATATATATATATATACATATATATA in one WCS read and TP28P1; type 5
Deletion of A in one WCS read and TP28P1; type 2 (single nucleotide insertions/deletions)
Insertion of TTG in one WCS read; type 5
Deletion of TATATATA in one WCS read; type 5
Insertion of TTGTTGTTGTCG in TP28P1; type 5
Majority of WCS and TP28D20 call A, One WCS read and TP28P1 call G; type 1 (single nucleotide substitutions)
Insertion of TAATAA in one WCS read and TP28P1; type 5
Insertion of TTT in one WCS read and TP28P1; type 3 (insertion/deletion of 3 nucleotides)
WCS calls 9 A, TP28P1 calls 10 A; type 2 (single nucleotide insertions/deletions)
WCS call 4 A, TP28P1 calls 5 A; type 2 (single nucleotide insertions/deletions)
WCS call 5 A, TP28P1 calls 4 A; type 2 (single nucleotide insertions/deletions)
WCS calls T, TP28P1 calls A; type 1 (single nucleotide substitutions)
Insertion of AAAC in TP28P1; type 4 (insertion/deletion of 4 or 5 nucleotides)
WCS calls T, TP28P1 call A; type 1 (single nucleotide substitutions)
Insertion of AGAAAAGGAAAAAAATAAAC in TP28P1; type 6 (insertion/deletion of 6 or more nucleotides)
WCS and TP28D20 call T, TP28P1 calls G; type 1 (single nucleotide substitutions)
WCS and TP28D20 call C, TP28P1 calls G; type 1 (single nucleotide substitutions)
Signal peptide predicted for Tb927.1.4350 by SignalP 2.0 HMM (Signal peptide probabilty 0.806, signal anchor probability 0.192) with cleavage site probability 0.152 between residues 20 and 21
3 probable transmembrane helices predicted for Tb927.1.4350 by TMHMM2.0 at aa 2-24, 39-61 and 73-95
1 probable transmembrane helix predicted for Tb927.1.4360 by TMHMM2.0 at aa 13-35
Majority of WCS and TP28D20 call 10 A, One WCS read and TP28P1 call 9 A; type 2 (single nucleotide insertions/deletions)
Deletion of TG in two WCS reads and TP28P1; type 5
Signal anchor predicted for Tb927.1.4370 by SignalP 2.0 HMM (Signal peptide probabilty 0.184, signal anchor probability 0.800) with cleavage site probability 0.115 between residues 25 and 26
1 probable transmembrane helix predicted for Tb927.1.4370 by TMHMM2.0 at aa 5-27
WCS and TP25O14 call A, TP28P1 calls T; type 1 (single nucleotide substitutions); mis-sense mutation at 571 in Tb927.1.4370 T -> S
Majority of WCS call A, One WCS read and TP28P1 call G; type 1 (single nucleotide substitutions)
Majority of WCS call A, One WCS read and TP28P1 call T; type 1 (single nucleotide substitutions)
Deletion of ATATAT in one WCS read and TP28P1; type 5
Majority of WCS reads call A, One WCS read and TP28P1 call T; type 1 (single nucleotide substitutions)
Majority of WCS and TP28D20 call 9 T, One WCS read and TP28P1 call 10 T; type 2 (single nucleotide insertions/deletions)
Signal peptide predicted for Tb927.1.4380 by SignalP 2.0 HMM (Signal peptide probabilty 0.995, signal anchor probability 0.005) with cleavage site probability 0.470 between residues 18 and 19
1 probable transmembrane helix predicted for Tb927.1.4380 by TMHMM2.0 at aa 5-27
WCS and TP1H9 call 10 C, TP28P1 calls 9 C; type 2 (single nucleotide insertions/deletions)
Majority of WCS and TP1H9 call 10 A, One WCS read and TP28P1 call 9 A; type 2 (single nucleotide insertions/deletions)
1 probable transmembrane helix predicted for Tb927.1.4390 by TMHMM2.0 at aa 13-30
Majority of WCS, TP28D20 and TP25O14 call 10 T, One WCS read and TP28P1 call 11 T; type 2 (single nucleotide insertions/deletions)
Majority of WCS, TP25O14 and TP28D20 call G, One WCS read calls A; type 1 (single nucleotide substitutions)
Majority of WCS and TP28D20 call G, One WCS read calls A; type 1 (single nucleotide substitutions)
Majority of WCS, TP28D20 and TP25O14call C, One WCS read and TP28P1 call T; type 1 (single nucleotide substitutions); mis-sense mutation at 72 in Tb927.1.4410 P -> K
WCS calls A, TP28P1 calls T; type 1 (single nucleotide substitutions)
Majority of WCS call T, One WCS read and TP28P1 call G; type 1 (single nucleotide substitutions); mis-sense mutation at 481 in Tb927.1.4420 F -> V
Majority of WCS reads, TP28D20 and TP25O14 call C, One WCS read and TP28P1 call T; type 1 (single nucleotide substitutions)
WCS, TP28D20 and TP25O14 call A, TP28P1 calls G; type 1 (single nucleotide substitutions); mis-sense mutation at 646 in Tb927.1.4420 N -> D
Signal peptide predicted for Tb927.1.4430 by SignalP 2.0 HMM (Signal peptide probabilty 0.810, signal anchor probability 0.142) with cleavage site probability 0.151 between residues 41 and 42
1 probable transmembrane helix predicted for Tb927.1.4430 by TMHMM2.0 at aa 25-47
Deletion of GGG in TP28P1; type 3 (insertion/deletion of 3 nucleotides)
WCS and TP28D20 call C, TP28P1 calls A; type 1 (single nucleotide substitutions); mis-sense mutation at 81 in Tb927.1.4430 A -> D
WCS calls C, TP28P1 calls G; type 1 (single nucleotide substitutions)
WCS call 5 T, TP28P1 calls 6 T; type 2 (single nucleotide insertions/deletions)
Majority of WCS and TP28D20 call A, One WCS read calls G; type 1 (single nucleotide substitutions)
Majority of WCS and TP28D20 call T, One WCS read calls G; type 1 (single nucleotide substitutions)
Deletion of TATGTGTGTG in one WCS read; type 5
unlikely gene; low complexity composition
Signal anchor predicted for Tb927.1.4440 by SignalP 2.0 HMM (Signal peptide probabilty 0.007, signal anchor probability 0.824) with cleavage site probability 0.002 between residues 48 and 49
Majority of WCS and TP28D20 call C, One WCS read and TP28P1 call T; type 1 (single nucleotide substitutions)
4 probable transmembrane helices predicted for Tb927.1.4440 by TMHMM2.0 at aa 30-52, 67-89, 96-118 and 133-155
Majority of WCS and TP28D20 call 8 G, One WCS read and TP28P1 call 9 G; type 2 (single nucleotide insertions/deletions)
Insertion of TTCTTTTTT in one WCS read and TP28P1; type 5
Deletion of TC in one WCS read and TP28P1; type 5
WCS and TP1C9 call T, TP28P1 calls C; type 1 (single nucleotide substitutions); mis-sense mutation at 799 in Tb927.1.4450 C -> R
Majority of WCS, TP1C9 and TP28D20 call G, One WCS read and TP28P1 call A; type 1 (single nucleotide substitutions)
GPI-Anchor Signal predicted for Tb927.1.4460 by DGPI v2.04 with cleavage site probability 0.51600003 near 40
Signal peptide predicted for Tb927.1.4460 by SignalP 2.0 HMM (Signal peptide probabilty 0.685, signal anchor probability 0.182) with cleavage site probability 0.188 between residues 18 and 19
1 probable transmembrane helix predicted for Tb927.1.4460 by TMHMM2.0 at aa 23-45
WCS, TP28D20 and TP1C9 call G, TP28P1 calls A; type 1 (single nucleotide substitutions); mis-sense mutation at 542 in Tb927.1.4480 R -> H
WCS and TP28D20 call A, TP28P1 calls G; type 1 (single nucleotide substitutions); mis-sense mutation at 1086 in Tb927.1.4480 N -> S
WCS and TP28D20 call G, TP28P1 calls A; type 1 (single nucleotide substitutions); mis-sense mutation at 1128 in Tb927.1.4480 S -> N
WCS and TP28D20 call T, TP28P1 calls C; type 1 (single nucleotide substitutions); mis-sense mutation at 1204 in Tb927.1.4480 V -> A
WCS and TP28D20 call C, TP28P1 calls G; type 1 (single nucleotide substitutions); mis-sense mutation at 1289 in Tb927.1.4480 T -> R
Majority of WCS and TP1C9 call T, One WCS read calls G; type 1 (single nucleotide substitutions); mis-sense mutation at 1484 in Tb927.1.4480 L -> V
WCS and TP1C9 call G, TP28P1 calls T; type 1 (single nucleotide substitutions)
WCS and TP1C9 call C, TP28P1 calls T; type 1 (single nucleotide substitutions)
WCS, TP1C9 and TP28D20 call G, TP28P1 calls A; type 1 (single nucleotide substitutions)
WCS, TP1C9 and TP28D20 call 9 T, TP28P1 calls 8 T; type 2 (single nucleotide insertions/deletions)
WCS, TP1C9 and TP28D20 call A, TP28P1 calls G; type 1 (single nucleotide substitutions)
Signal anchor predicted for Tb927.1.4500 by SignalP 2.0 HMM (Signal peptide probabilty 0.029, signal anchor probability 0.960) with cleavage site probability 0.012 between residues 45 and 46
6 probable transmembrane helices predicted for Tb927.1.4500 by TMHMM2.0 at aa 21-40, 55-77, 114-136, 140-162, 222-244 and 266-284
1 probable transmembrane helix predicted for Tb927.1.4510 by TMHMM2.0 at aa 69-91
Deletion of CATTT in one WCS read; type 5
Majority of WCS, TP1C9 and TP28D20 call T, One WCS read and TP28P1 call A; type 1 (single nucleotide substitutions)
Signal peptide predicted for Tb927.1.4530 by SignalP 2.0 HMM (Signal peptide probabilty 0.978, signal anchor probability 0.022) with cleavage site probability 0.364 between residues 21 and 22
1 probable transmembrane helix predicted for Tb927.1.4530 by TMHMM2.0 at aa 7-29
WCS, TP1C9, TP19A1 and TP28D20 call 10 G, TP28P1 calls 11 G; type 2 (single nucleotide insertions/deletions)
Majority of WCS, TP19A1, TP1C9 and TP28D20 call 10 A, One WCS read and TP28P1 call 12 A; type 6 (insertion/deletion of 2 nucleotides)
Majority of WCS, TP19A1, TP1C9 and TP28D20 call A, One WCS read and TP28P1 call G; type 1 (single nucleotide substitutions)
Insertion of T in one WCS read and TP28P1; type 2 (single nucleotide insertions/deletions)
WCS and TP19A1 call A, TP28P1 call G; type 1 (single nucleotide substitutions); mis-sense mutation at 4 in Tb927.1.4540 K -> E
Majority of WCS and TP19A1 call A, One WCS read and TP28P1 call G; type 1 (single nucleotide substitutions); mis-sense mutation at 7 in Tb927.1.4540 N -> S
Majority of WCS and TP19A1 call T, One WCS read and TP28P1 call A; type 1 (single nucleotide substitutions)
Majority of WCS and TP19A1 call A, One WCS read and TP28P1 call G; type 1 (single nucleotide substitutions); mis-sense mutation at 16 in Tb927.1.4540 T -> A
Majority of WCS and TP28D20 call T, Two WCS reads and TP28P1 call C; type 1 (single nucleotide substitutions)
Majority of WCS, TP28D20 and TP1C9 call C, One WCS read and TP28P1 call T; type 1 (single nucleotide substitutions); mis-sense mutation at 405 in Tb927.1.4540 S -> L
Majority of WCS, TP28D20 and TP1C9 call A, One WCS read and TP28P1 call G; type 1 (single nucleotide substitutions); mis-sense mutation at 406 in Tb927.1.4540 Q -> R
weak similarity to ATP synthase a chain (EC 3.6.3.14) (ATPase protein 6). (Swiss-Prot:P24499) (Trypanosoma brucei brucei;)
Signal anchor predicted for Tb927.1.4550 by SignalP 2.0 HMM (Signal peptide probabilty 0.071, signal anchor probability 0.922) with cleavage site probability 0.015 between residues 38 and 39
3 probable transmembrane helices predicted for Tb927.1.4550 by TMHMM2.0 at aa 9-31, 46-68 and 89-111
Two WCS reads call T, One WCS read calls C; type 1 (single nucleotide substitutions)
Majority of WCS call C, One WCS read and TP28P1 call T; type 1 (single nucleotide substitutions)
Signal anchor predicted for Tb927.1.4570 by SignalP 2.0 HMM (Signal peptide probabilty 0.036, signal anchor probability 0.957) with cleavage site probability 0.010 between residues 33 and 34
3 probable transmembrane helices predicted for Tb927.1.4570 by TMHMM2.0 at aa 9-31, 46-68 and 75-97
WCS, TP19A1 and TP1C9 call C, TP28P1 calls T; type 1 (single nucleotide substitutions)
WCS, TP1C9 and TP28D20 call C, TP28P1 calls T; type 1 (single nucleotide substitutions)
Signal anchor predicted for Tb927.1.4590 by SignalP 2.0 HMM (Signal peptide probabilty 0.071, signal anchor probability 0.922) with cleavage site probability 0.015 between residues 38 and 39
3 probable transmembrane helices predicted for Tb927.1.4590 by TMHMM2.0 at aa 9-31, 46-68 and 89-111
WCS and TP1C9 call G, TP28P1 calls A; type 1 (single nucleotide substitutions)
Signal anchor predicted for Tb927.1.4610 by SignalP 2.0 HMM (Signal peptide probabilty 0.158, signal anchor probability 0.821) with cleavage site probability 0.058 between residues 37 and 38
1 probable transmembrane helix predicted for Tb927.1.4610 by TMHMM2.0 at aa 15-37
Signal anchor predicted for Tb927.1.4620 by SignalP 2.0 HMM (Signal peptide probabilty 0.071, signal anchor probability 0.922) with cleavage site probability 0.015 between residues 38 and 39
3 probable transmembrane helices predicted for Tb927.1.4620 by TMHMM2.0 at aa 9-31, 46-68 and 89-111
Deletion of CGTTTCATTTACTATTTTATTTTACTTT;in one WCS read; type 5
Majority of WCS callS G, One WCS read calls A; type 1 (single nucleotide substitutions)
Signal anchor predicted for Tb927.1.4640 by SignalP 2.0 HMM (Signal peptide probabilty 0.158, signal anchor probability 0.821) with cleavage site probability 0.058 between residues 37 and 38
1 probable transmembrane helix predicted for Tb927.1.4640 by TMHMM2.0 at aa 15-37
Majority of WCS, TP1C9 and TP19A1 call T, One WCS read and TP28P1 call C; type 1 (single nucleotide substitutions)
Majority of WCS, TP1C9 and TP19A1 call G, One WCS read and TP28P1 call T; type 1 (single nucleotide substitutions)
Majority of WCS, TP1C9 and TP19A1 call C, One WCS read and TP28P1 calls T; type 1 (single nucleotide substitutions)
1 probable transmembrane helix predicted for Tb927.1.4660 by TMHMM2.0 at aa 56-78
WCS, TP1C9, TP19A1 and TP28D20 call 11 A, TP28P1 calls 12 A; type 2 (single nucleotide insertions/deletions)
WCS, TP1C9 and TP19A1 call T, TP28P1 calls C; type 1 (single nucleotide substitutions)
Signal anchor predicted for Tb927.1.4660 by SignalP 2.0 HMM (Signal peptide probabilty 0.001, signal anchor probability 0.825) with cleavage site probability 0.000 between residues 18 and 19
2 probable transmembrane helices predicted for Tb927.1.4670 by TMHMM2.0 at aa 21-43 and 58-80
Signal anchor predicted for Tb927.1.4670 by SignalP 2.0 HMM (Signal peptide probabilty 0.386, signal anchor probability 0.601) with cleavage site probability 0.324 between residues 45 and 46
WCS and TP1C9 call 10 A, TP28P1 calls 11 A; type 2 (single nucleotide insertions/deletions)
WCS calls A, TP28P1 calls C; type 1 (single nucleotide substitutions)
WCS calls A, TP28P1 calls G; type 1 (single nucleotide substitutions)
WCS, TP28D20 and TP1C9 call C, TP28P1 calls T; type 1 (single nucleotide substitutions)
WCS, TP28D20 and TP1C9 call C, TP28P1 calls A; type 1 (single nucleotide substitutions)
Insertion of TCTCTTACT in TP28P1; type 5
Deletion of ATTTGATTTG in TP28P1; type 5
WCS, TP28D20 and TP1C9 call 8 A, TP28P1 calls 9 A; type 2 (single nucleotide insertions/deletions)
WCS, TP28D20 and TP1C9 call 10 A, TP28P1 calls 9 A; type 2 (single nucleotide insertions/deletions)
Majority of WCS and TP1C9 call 10 T, One WCS read and TP28P1 call 11 T; type 2 (single nucleotide insertions/deletions)
Majority of WCS, TP28D20 and TP1C9 call T, One WCS read calls A; type 1 (single nucleotide substitutions)
Insertion of ATATAATATATATATA in one WCS read; type 5
Majority of WCS, TP1C9 and TP28D20 call T, One WCS read calls C; type 1 (single nucleotide substitutions)
Insertion of TTCT in one WCS read; type 4 (insertion/deletion of 4 or 5 nucleotides)
Majority of WCS, TP1C9 and TP19A1 call T, One WCS read and TP28P1 calls C; type 1 (single nucleotide substitutions)
WCS, TP1C9 and TP19A1 call A, TP28P1 calls G; type 1 (single nucleotide substitutions)
WCS and TP19A1 call 10 T, TP28P1 calls 9 T; type 2 (single nucleotide insertions/deletions)
WCS and TP1C9 call T, TP28P1 calls C; type 1 (single nucleotide substitutions)
WCS, TP1C9 and TP19A1 call 10 T, TP28P1 calls 12 T; type 2 (single nucleotide insertions/deletions)
WCS, TP1C9 and TP19A1 call G, TP28P1 calls A; type 1 (single nucleotide substitutions)
WCS and TP1C9 call A, TP28P1 calls G; type 1 (single nucleotide substitutions); mis-sense mutation at 210 in Tb927.1.4740 D -> G
WCS and TP1C9 call C, TP28P1 calls T; type 1 (single nucleotide substitutions); mis-sense mutation at 230 in Tb927.1.4740 S -> F
WCS reads and TP1C9 call A, TP28P1 calls G; type 1 (single nucleotide substitutions); mis-sense mutation at 507 in Tb927.1.4740 T -> A
WCS reads and TP1C9 call G, TP28P1 calls A; type 1 (single nucleotide substitutions)
WCS calls C, TP28P1 calls A; type 1 (single nucleotide substitutions)
WCS and TP1C9 call A, TP28P1 calls G; type 1 (single nucleotide substitutions)
1 probable transmembrane helix predicted for Tb927.1.4770 by TMHMM2.0 at aa 6-25
serine peptidase; serine peptidase, Clan SC, Family S9D
WCS and TP19A1 call T, TP28P1 calls C; type 1 (single nucleotide substitutions); mis-sense mutation at 137 in Tb927.1.4780 C -> R
Signal anchor predicted for Tb927.1.4790 by SignalP 2.0 HMM (Signal peptide probabilty 0.096, signal anchor probability 0.877) with cleavage site probability 0.082 between residues 38 and 39
3 probable transmembrane helices predicted for Tb927.1.4790 by TMHMM2.0 at aa 20-38, 51-73 and 93-115
Majority of WCS and TP1C9 call G, One WCS read and TP28P1 call A; type 1 (single nucleotide substitutions)
Majority of WCS and TP1C9 call G, One WCS read calls C; type 1 (single nucleotide substitutions); mis-sense mutation at 302 in Tb927.1.4800 A -> P
WCS and TP1C9 call 8 T, TP28P1 calls 7 T; type 2 (single nucleotide insertions/deletions)
hypothetical protein conserved (pseudogene)
WCS and TP1C9 call 5 T, TP28P1 calls 4 T; type 2 (single nucleotide insertions/deletions)
WCS and TP1C9 call C, TP28P1 calls A; type 1 (single nucleotide substitutions)
GPI-Anchor Signal predicted for Tb927.1.4820 by DGPI v2.04, no cleavage site predicted
Majority of WCS and TP1C9 call A, One WCS read calls G; type 1 (single nucleotide substitutions)
Majority of WCS and TP1C9 call T, One WCS read calls C; type 1 (single nucleotide substitutions)
Majority of WCS and TP1C9 call G, One WCS read calls A; type 1 (single nucleotide substitutions)
Majority of WCS reads and TP1C9 call 2 T, One WCS read calls 5 T; type 3 (insertion/deletion of 3 nucleotides)
Majority of WCS and TP1C9 call 11 A, One WCS read calls 9 A; type 6 (insertion/deletion of 2 nucleotides)
Deletion of GAAA in one WCS read; type 5
Majority of WCS and TP1C9 call C, One WCS read calls T; type 1 (single nucleotide substitutions); mis-sense mutation at 4 in Tb927.1.4830 P -> S
Majority of WCS, TP19A1 and TP1C9 call C, One WCS read and TP28P1 call T; type 1 (single nucleotide substitutions)
Insertion of AGAAAAA in one WCS read and TP28P1; type 6 (insertion/deletion of 6 or more nucleotides)
Majority of WCS, TP19A1 and TP1C9 call A, One WCS read and TP28P1 call G; type 1 (single nucleotide substitutions)
Majority of WCS, TP19A1 and TP1C9 call 12 A, One WCS read and TP28P1 calls 10 A; type 6 (insertion/deletion of 2 nucleotides)
Majority of WCS and TP1C9 call C, One WCS read and TP28P1 call A; type 1 (single nucleotide substitutions)
1 probable transmembrane helix predicted for Tb927.1.4840 by TMHMM2.0 at aa 67-89
Majority of WCS and TP19A1 call G, Two WCS reads and TP28P1 call T; type 1 (single nucleotide substitutions)
Majority of WCS and TP19A1 call A, One WCS read and TP28P1 call G; type 1 (single nucleotide substitutions)
WCS calls 11 T, TP28P1 calls 10 T; type 2 (single nucleotide insertions/deletions)
WCS and TP1C9 call 6 A, TP28P1 calls 7 A; type 2 (single nucleotide insertions/deletions)
WCS and TP19A1 call G, TP28P1 calls A; type 1 (single nucleotide substitutions)
WCS and TP19A1 call T, TP28P1 calls C; type 1 (single nucleotide substitutions)
Insertion of ATT in TP28P1; type 3 (insertion/deletion of 3 nucleotides)
Majority of WCS call A, One WCS read and TP28P1 call G; type 1 (single nucleotide substitutions); mis-sense mutation at 54 in Tb927.1.4850 T -> A
Majority of WCS call C, One WCS read and TP28P1 call T; type 1 (single nucleotide substitutions); mis-sense mutation at 62 in Tb927.1.4850 A -> V
Majority of WCS and TP1C9 call C, One WCS read and TP28P1 call T; type 1 (single nucleotide substitutions)
Insertion of TA in one WCS read and TP28P1; type 6 (insertion/deletion of 2 nucleotides)
expression site-associated gene (ESAG, pseudogene), putative; expression site-associated gene 11 (ESAG11), pseudogene
Majority of WCS and TP1C9 call C, One WCS read calls T; type 1 (single nucleotide substitutions)
expression site-associated gene (ESAG) protein; expression site-associated gene 1 (ESAG1)
Signal peptide predicted for Tb927.1.4870 by SignalP 2.0 HMM (Signal peptide probabilty 0.925, signal anchor probability 0.003) with cleavage site probability 0.652 between residues 20 and 21
GPI-Anchor Signal predicted for Tb927.1.4890 by DGPI v2.04 with cleavage site probability 0.15599999 near 431
Signal peptide predicted for Tb927.1.4890 by SignalP 2.0 HMM (Signal peptide probabilty 0.963, signal anchor probability 0.007) with cleavage site probability 0.655 between residues 21 and 22
expression site-associated gene 11 (ESAG11) protein, putative
GPI-Anchor Signal predicted for Tb927.1.4900 by DGPI v2.04, no cleavage site predicted
Signal peptide predicted for Tb927.1.4900 by SignalP 2.0 HMM (Signal peptide probabilty 1.000, signal anchor probability 0.000) with cleavage site probability 0.484 between residues 24 and 25
Signal peptide predicted for Tb927.1.4910 by SignalP 2.0 HMM (Signal peptide probabilty 0.925, signal anchor probability 0.003) with cleavage site probability 0.652 between residues 20 and 21
Signal anchor predicted for Tb927.1.4940 by SignalP 2.0 HMM (Signal peptide probabilty 0.033, signal anchor probability 0.645) with cleavage site probability 0.012 between residues 57 and 58
1 probable transmembrane helix predicted for Tb927.1.4940 by TMHMM2.0 at aa 34-56
2 probable transmembrane helices predicted for Tb927.1.4950 by TMHMM2.0 at aa 31-53 and 60-82
Majority of WCS calls C, One WCS read calls T; type 1 (single nucleotide substitutions)
Majority of WCS calls A, One WCS read calls C; type 1 (single nucleotide substitutions)
Majority of WCS calls T, One WCS read calls C; type 1 (single nucleotide substitutions)
GPI-Anchor Signal predicted for Tb927.1.4960 by DGPI v2.04 with cleavage site probability 0.72 near 56
Signal peptide predicted for Tb927.1.4960 by SignalP 2.0 HMM (Signal peptide probabilty 0.838, signal anchor probability 0.107) with cleavage site probability 0.366 between residues 43 and 44
Majority of WCS calls C, One WCS read calls G; type 1 (single nucleotide substitutions); nonsense mutation at 12 in Tb927.1.4960 S -> *
2 probable transmembrane helices predicted for Tb927.1.4960 by TMHMM2.0 at aa 13-35 and 50-72
1 probable transmembrane helix predicted for Tb927.1.4980 by TMHMM2.0 at aa 7-29
Signal peptide predicted for Tb927.1.5010 by SignalP 2.0 HMM (Signal peptide probabilty 0.641, signal anchor probability 0.007) with cleavage site probability 0.468 between residues 22 and 23
Majority of WCS and TP19A1 call A, One WCS calls G; type 1 (single nucleotide substitutions); mis-sense mutation at 254 in Tb927.1.5030 H -> R
Majority of WCS and TP19A1 call T, One WCS calls C; type 1 (single nucleotide substitutions)
Majority of WCS and TP19A1 call G, One WCS calls A; type 1 (single nucleotide substitutions); mis-sense mutation at 307 in Tb927.1.5030 V -> I
Majority of WCS and TP19A1 call T, One WCS calls G; type 1 (single nucleotide substitutions)
Majority of WCS and TP19A1 call A, Four WCS reads call G; type 1 (single nucleotide substitutions)
Signal peptide predicted for Tb927.1.5040 by SignalP 2.0 HMM (Signal peptide probabilty 0.701, signal anchor probability 0.040) with cleavage site probability 0.365 between residues 29 and 30
1 probable transmembrane helix predicted for Tb927.1.5040 by TMHMM2.0 at aa 13-35
Majority of WCS and TP19A1 call T, Three WCS reads call C; type 1 (single nucleotide substitutions); mis-sense mutation at 17 in Tb927.1.5040 F -> L
Majority of WCS and TP19A1 call G, Three WCS reads call A; type 1 (single nucleotide substitutions); mis-sense mutation at 50 in Tb927.1.5040 V -> I
Majority of WCS and TP19A1 call G, Four WCS reads call A; type 1 (single nucleotide substitutions)
Majority of WCS and TP19A1 call 8 T, Four WCS reads call 9 T; type 2 (single nucleotide insertions/deletions)
Majority of WCS and TP19A1 call T, Four WCS reads call C; type 1 (single nucleotide substitutions)
Majority of WCS call A, Three WCS reads call G; type 1 (single nucleotide substitutions)
Majority of WCS call A, Three WCS reads call C; type 1 (single nucleotide substitutions)
Majority of WCS call G, Two WCS reads call T; type 1 (single nucleotide substitutions)
variant surface glycoprotein (VSG)-related, putative
GPI-Anchor Signal predicted for Tb927.1.5060 by DGPI v2.04 with cleavage site probability 2.4940002 near 327
Signal peptide predicted for Tb927.1.5060 by SignalP 2.0 HMM (Signal peptide probabilty 0.938, signal anchor probability 0.042) with cleavage site probability 0.466 between residues 21 and 22
expression site-associated gene (ESAG) protein; expression site-associated gene 9 (ESAG9)
GPI-Anchor Signal predicted for Tb927.1.5080 by DGPI v2.04 with cleavage site probability 2.3220003 near 240
Signal peptide predicted for Tb927.1.5080 by SignalP 2.0 HMM (Signal peptide probabilty 0.993, signal anchor probability 0.001) with cleavage site probability 0.241 between residues 23 and 24
GPI-Anchor Signal predicted for Tb927.1.5100 by DGPI v2.04 with cleavage site probability 0.15599999 near 435
GPI-Anchor Signal predicted for Tb927.1.5110 by DGPI v2.04, no cleavage site predicted
Signal peptide predicted for Tb927.1.5110 by SignalP 2.0 HMM (Signal peptide probabilty 1.000, signal anchor probability 0.000) with cleavage site probability 0.272 between residues 21 and 22
Signal peptide predicted for Tb927.1.5120 by SignalP 2.0 HMM (Signal peptide probabilty 0.914, signal anchor probability 0.004) with cleavage site probability 0.617 between residues 20 and 21
Signal peptide predicted for Tb927.1.5130 by SignalP 2.0 HMM (Signal peptide probabilty 0.993, signal anchor probability 0.002) with cleavage site probability 0.824 between residues 25 and 26
1 probable transmembrane helix predicted for Tb927.1.5130 by TMHMM2.0 at aa 5-27
1 probable transmembrane helix predicted for Tb927.1.5140 by TMHMM2.0 at aa 61-83
Signal peptide predicted for Tb927.1.5170 by SignalP 2.0 HMM (Signal peptide probabilty 0.996, signal anchor probability 0.002) with cleavage site probability 0.700 between residues 21 and 22
Signal peptide predicted for Tb927.1.5200 by SignalP 2.0 HMM (Signal peptide probabilty 0.998, signal anchor probability 0.001) with cleavage site probability 0.645 between residues 20 and 21
expression site-associated gene 9 (ESAG9) protein, putative
GPI-Anchor Signal predicted for Tb927.1.5220 by DGPI v2.04 with cleavage site probability 0.64800006 near 278
Signal peptide predicted for Tb927.1.5220 by SignalP 2.0 HMM (Signal peptide probabilty 1.000, signal anchor probability 0.000) with cleavage site probability 0.752 between residues 23 and 24
expression site-associated gene 1 (ESAG1) protein, putative
Signal peptide predicted for Tb927.1.5240 by SignalP 2.0 HMM (Signal peptide probabilty 0.989, signal anchor probability 0.009) with cleavage site probability 0.581 between residues 21 and 22
GPI-Anchor Signal predicted for Tb927.1.5260 by DGPI v2.04 with cleavage site probability 2.1199 near 157
Signal anchor predicted for Tb927.1.5260 by SignalP 2.0 HMM (Signal peptide probabilty 0.253, signal anchor probability 0.741) with cleavage site probability 0.148 between residues 63 and 64
2 probable transmembrane helices predicted for Tb927.1.5260 by TMHMM2.0 at aa 24-46 and 50-72
ingi. Several point mutations (pers. comm. F. Bringaud)
inferred VSG 3' UTR, partim; TGCTACT heptamer derived from published consensus (Berberof et al. 1995; Majumder, Boothroyd and Weber, 1981); VSG 3'-UTR 7-mer
GPI-Anchor Signal predicted for Tb927.1.5300 by DGPI v2.04 with cleavage site probability 0.344 near 442
Signal peptide predicted for Tb927.1.5300 by SignalP 2.0 HMM (Signal peptide probabilty 0.906, signal anchor probability 0.000) with cleavage site probability 0.471 between residues 19 and 20
GPI-Anchor Signal predicted for Tb927.1.5310 by DGPI v2.04 with cleavage site probability 1.1019999 near 92
Signal peptide predicted for Tb927.1.5310 by SignalP 2.0 HMM (Signal peptide probabilty 0.827, signal anchor probability 0.172) with cleavage site probability 0.747 between residues 29 and 30
2 probable transmembrane helices predicted for Tb927.1.5310 by TMHMM2.0 at aa 21-43 and 53-75
variant surface glycoprotein (VSG, atypical), putative
GPI-Anchor Signal predicted for Tb927.1.5330 by DGPI v2.04, no cleavage site predicted
Signal peptide predicted for Tb927.1.5330 by SignalP 2.0 HMM (Signal peptide probabilty 1.000, signal anchor probability 0.000) with cleavage site probability 0.580 between residues 20 and 21
expression site-associated gene (ESAG, pseudogene), putative; expression site-associated gene 3 (ESAG3), pseudogene