Trypanosoma brucei brucei TREU927 chromosome 9, whole genome shotgun sequence.
Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina; Trypanosomatida; Trypanosomatidae; Trypanosoma.
The genome of the African trypanosome Trypanosoma brucei
Comparative genomics of trypanosomatid parasitic protozoa
Submitted (10-APR-2018) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (14-APR-2005) Wellcome Trust Genome Campus, The Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK
PROVISIONAL REFSEQ: This record has not yet been subject to final\nNCBI review. The reference sequence is identical to CM000207.\nTrypanosoma brucei chromosomes 9 to 11 were isolated and then\nsequenced by the Wellcome Trust Sanger Institute, using a whole\nchromosome shotgun approach. The sequences are therefore, likely to\nrepresent a 'mosaic' assembly of both chromosomal homologs.\nDetails of Trypanosoma sequencing at the Sanger Institute are\navailable on the World Wide Web. (URL,\nhttp://www.sanger.ac.uk/Projects/T_brucei/) and via the GeneDB\ndatabase (www.genedb.org).\nPredicted protein coding regions (>30 codons) were manually revised\nin the light of similarity data, domain information and orthology\nto Leishmania major and Trypanosoma cruzi. Gene products were\nassigned putative functions based on similarity with experimentally\ncharacterized gene products or the presence of predicted protein\ndomains. Products were labelled either 'hypothetical protein', or\n'hypothetical protein, conserved' when showing significant\nsimilarity with proteins or domains of unknown function from other\norganisms. Short predicted coding sequences (less than 150 codons)\nwith no additional evidence of coding potential were labeled\n'hypothetical protein, unlikely'.\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: INSDC submitter\nAnnotation Status :: Full annotation\nAnnotation Pipeline :: Eukaryotic Annotation Propagation Pipeline\n##Genome-Annotation-Data-END##
single VAT derivative of TREU (Trypanosomiasis Research Edinburgh University) 927/4 (GPAL/KE/70/EATRO 1534)
variant surface glycoprotein (VSG, pseudogene), putative
GPI-Anchor Signal predicted for Tb09.354.0060 by DGPI v2.04 with cleavage site probability 0.344 near 469
expression site-associated gene (ESAG, pseudogene), putative
GPI-Anchor Signal predicted for Tb09.354.0090 by DGPI v2.04 with cleavage site probability 0.75399995 near 476
GPI-Anchor Signal predicted for Tb09.354.0180 by DGPI v2.04 with cleavage site probability 2.4940002 near 486
GPI-Anchor Signal predicted for Tb09.142.0190 by DGPI v2.04, no cleavage site predicted
GPI-Anchor Signal predicted for Tb09.142.0240 by DGPI v2.04 with cleavage site probability 0.75399995 near 509
variant surface glycoprotein (VSG)-related, putative
similar to GB:CAD53280.1: ESAG9 (expression site-associated gene 9) protein, possible {Trypanosoma brucei;}
GPI-Anchor Signal predicted for Tb09.142.0410 by DGPI v2.04 with cleavage site probability 0.684 near 79
UDP-Gal/UDP-GlcNAc-dependent glycosyltransferase
variant surface glycoprotein (VSG, pseudogene), putative; degenerate and frameshifted
variant surface glycoprotein (VSG, pseudogene), putative; interrupted by an ingi element (the coordinates of which may have to be refined)
variant surface glycoprotein (VSG, pseudogene), putative; frameshifted fragment
variant surface glycoprotein (VSG, pseudogene), putative; degenerate
variant surface glycoprotein (VSG, pseudogene), putative; frameshifted and point mutation
variant surface glycoprotein (VSG, pseudogene), putative; frameshifted and degenerate
variant surface glycoprotein (VSG, pseudogene), putative; fragment
GPI-Anchor Signal predicted for Tb09.160.0110 by DGPI v2.04 with cleavage site probability 0.344 near 484
variant surface glycoprotein (VSG, pseudogene), putative; point mutation
expression site-associated gene 3 (ESAG3, pseudogene), putative; pers. comm. L. Marcello, Univ. of Glasgow.
variant surface glycoprotein (VSG, pseudogene), putative; degenerate and frameshifted fragment
GPI-Anchor Signal predicted for Tb09.160.0160 by DGPI v2.04 with cleavage site probability 0.64800006 near 466
variant surface glycoprotein (VSG), pseudogene
variant surface glycoprotein (VSG, pseudogene), putative; fragment with point mutation
variant surface glycoprotein (VSG, pseudogene), putative; degenerate frameshifted
expression site-associated gene 3 (ESAG3, pseudogene), putative; degenerate fragment
GPI-Anchor Signal predicted for Tb09.160.0260 by DGPI v2.04 with cleavage site probability 2.4940002 near 519
ingi element, ingi-like sequence - needs to be refined
GPI-Anchor Signal predicted for Tb09.160.0280 by DGPI v2.04 with cleavage site probability 0.78000003 near 505
Blast and PFAM similarity to monooxygenases and hydroxylases
GPI-Anchor Signal predicted for Tb09.160.0430 by DGPI v2.04 with cleavage site probability 0.156 near 780
curated by M. Parsons, P. Ward, J. Mottram
contains D-alanine-D-alanine ligase domain
serine/threonine protein phosphatase, putative
Mov34/MPN/PAD-1 metallopeptidase, putative
curated by J. Mottram; similar to C6.1A protein (Swiss-Prot:P46737) (Mus musculus) and similar to C6.1A protein. (Swiss-Prot:P46736) (Homo sapiens;)
peroxisomal membrane protein 4, putative
similar to SEC1-family transport protein SLY1 (AtSLY1) (Swiss-Prot:Q9SL48) (Arabidopsis thaliana)
similar to GB:AAF78898.1: YIP1B {Mus musculus;}
invariant surface glycoprotein 100 (pseudogene), putative; point mutation
GPI-Anchor Signal predicted for Tb09.160.0930 by DGPI v2.04, no cleavage site predicted
small ubiquitin-related modifier protein SUMO1/Ulp2
GPI-Anchor Signal predicted for Tb09.160.1050 by DGPI v2.04, no cleavage site predicted
serine/threonine protein kinase, putative
electon transport protein SCO1/SCO2, putative
mitotubule-associated protein Gb4, putative
Tb927 protein has large inserts of repeat expansion; similar to GB:AAK91760.1: cytoplasmic dynein heavy chain 2 {Ustilago maydis}
possible EB1 microtubule plus-end capping protein (curated by B. Wickstead, Univ. of Oxford)
GPI-Anchor Signal predicted for Tb09.160.1510 by DGPI v2.04, no cleavage site predicted
similar to Cytidine deaminase (EC 3.5.4.5) (Cytidine aminohydrolase). (Swiss-Prot:P32320) (Homo sapiens)
GPI-Anchor Signal predicted for Tb09.160.1750 by DGPI v2.04, no cleavage site predicted
cytochrome c oxidase subunit V, putative
personal communication from M. Mayho, P. Craddy & K. Matthews
acidocalcisomal exopolyphosphatase, putative
similar to Ribosomal large subunit pseudouridine synthase C (EC 4.2.1.70)(Pseudouridylate synthase) (Uracil hydrolyase). (Swiss-Prot:Q92IS6) (Rickettsia conorii)
contains Pfam PF00583: acetyltransferase, GNAT family
GPI-Anchor Signal predicted for Tb09.160.2030 by DGPI v2.04, no cleavage site predicted
endo-beta-N-acetylglucosaminidase, putative
53# similar to GB:AAM80487.1: endo-beta-N- acetylglucosaminidase {Homo sapiens;}
cyclophilin type peptidyl-prolyl cis-trans isomerase, putative
GPI-Anchor Signal predicted for Tb09.160.2080 by DGPI v2.04 with cleavage site probability 0.12900001 near 121
U6 snRNA-associated Sm-like protein LSm6p
identical to GB:AAS57928.1: Lsm6p {Trypanosoma brucei;} (PMID:14990572)
RIME-less ingi element; annotation to be refined; previous_systematic_id=Tb09.v1.0120
ingi element; blast hit to TBINGIC_3, 2967..1514 score: 2258 percent id: 95.00 EMBL:M16068, 5204 bp
similar to Syntaxin 72 (AtSYP72). (Swiss- Prot:Q94KK6) (Arabidopsis thaliana)
identical to GB:AAF19437.1: fatty acyl CoA synthetase 1 {Trypanosoma brucei;}
identical to GB:AAF19438.1: fatty acyl CoA synthetase 2 {Trypanosoma brucei;}
identical to GB:AAF19439.1: fatty acyl CoA synthetase 3 {Trypanosoma brucei;}
identical to GB:AAF19440.1: fatty acyl CoA synthetase 4 {Trypanosoma brucei;}
GPI-Anchor Signal predicted for Tb09.160.2880 by DGPI v2.04, no cleavage site predicted
weak similarity to TBC1 domain family member 1. (Swiss-Prot:Q60949) (Mus musculus;)
DNA-damage inducible protein DDI1-like protein
mitochondrial processing peptide subunit beta
curated by J. Mottram; similar to Ubiquinol- cytochrome C reductase complex core protein I, mitochondrialprecursor (EC 1.10.2.2) (Swiss-Prot:P43264) (Euglena gracilis); similar to Mitochondrial processing peptidase beta subunit, mitochondrialprecu
ubiquitin-activating enzyme E1, putative
similar to RUB-activating enzyme (Ubiquitin activating enzyme E1 like protein) (Swiss-Prot:O65041) (Arabidopsis thaliana)
eukaryotic initiation factor 4a, putative
GPI-Anchor Signal predicted for Tb09.160.3350 by DGPI v2.04 with cleavage site probability 0.408 near 62
GPI-Anchor Signal predicted for Tb09.160.3380 by DGPI v2.04, no cleavage site predicted
glucose transporter (pseudogene), putative
presenilin-like aspartic peptidase, putative
GPI-Anchor Signal predicted for Tb09.160.3510 by DGPI v2.04 with cleavage site probability 0.24939999 near 336
identical/ similar to GB:AAG43461.1: cyclic nucleotide phosphodiesterase {Trypanosoma brucei}
similar to NHP2-like protein 1 (High mobility group-like nuclear protein 2homolog 1) ((U4/U6.U5) tri- snRNP 15.5 kDa protein) (Sperm specificantigen 1) (Fertilization antigen 1) (FA-1). (Swiss-Prot:Q9D0T1) (Mus musculus;)
GPI-Anchor Signal predicted for Tb09.160.3680 by DGPI v2.04 with cleavage site probability 2.4940002 near 15
phosphomevalonate kinase protein, putative
similar to Phosphomevalonate kinase (EC 2.7.4.2) (Swiss-Prot:P24521) (Saccharomyces cerevisiae)
GPI-Anchor Signal predicted for Tb09.160.3770 by DGPI v2.04 with cleavage site probability 2.5800002 near 30
likely role in F-actin nucleation as part of complex with ARP2 (curated by B. Wickstead, Univ. of Oxford); similar to SP:P53490: Actin-like protein 3. {Acanthamoeba castellanii;}
actin-like protein 1, ungrouped (curated by B. Wickstead, Univ. of Oxford); similar to SP:P53500: Actin. {Cyanidioschyzon merolae}
GPI-Anchor Signal predicted for Tb09.160.4010 by DGPI v2.04 with cleavage site probability 0.348 near 28
ubiquitin carboxyl-terminal hydrolase, putative
identical to DNA topoisomerase II (EC 5.99.1.3)(Swiss-Prot:P12531) (Trypanosoma brucei brucei)
inositol/phosphatidylinositol phosphatase, putative
GPI-Anchor Signal predicted for Tb09.160.4180 by DGPI v2.04 with cleavage site probability 0.14039999 near 767
nucleosome assembly protein-like protein
farnesyl pyrophosphate synthetase, putative
similar to Hexaprenyl pyrophosphate synthetase, mitochondrial precursor(EC 2.5.1.-) (HPS). (Swiss- Prot:P18900) (Saccharomyces cerevisiae)
GPI-Anchor Signal predicted for Tb09.160.4410 by DGPI v2.04 with cleavage site probability 0.64089996 near 9
NAD/FAD dependent dehydrogenase, putative
similar to 40S ribosomal protein S3. (Swiss- Prot:Q06559) (Drosophila melanogaster)
protein phosphatase 2A regulatory subunit, putative
similar to Arginine kinase (EC 2.7.3.3) (AK). (Swiss-Prot:Q9NH49) (Callinectes sapidus;)
similar to Arginine kinase (EC 2.7.3.3) (AK). (Swiss-Prot:Q9NH49) (Callinectes sapidus)
inositol-1(or 4)-monophosphatase, putative
similar to Inositol-1(or 4)-monophosphatase 3 (EC 3.1.3.25) (IMPase 3) (IMP 3)(Inositol monophosphatase 3) (Swiss-Prot:P54928) (Lycopersicon esculentum)
Rab geranylgeranyl transferase component A, putative
weak similarity to NADH-ubiquinone oxidoreductase chain 5 (EC 1.6.5.3). (Swiss-Prot:P04540) (Trypanosoma brucei brucei;)
similar to metal ion-dependent hydrolase related to Alanyl-tRNA synthetase
GPI-Anchor Signal predicted for Tb09.160.4900 by DGPI v2.04 with cleavage site probability 0.78000003 near 81
similar over entire length to Splicing factor, arginine/serine-rich 3 (Pre-mRNA splicing factorSRP20) (X16 protein). (Swiss-Prot:P23152) (Homo sapiens;Mus musculus;)
cAMP-specific phosphodiesterase, putative
identical to GB:CAC39257.1: Rrp40p homologue {Trypanosoma brucei}
GPI-Anchor Signal predicted for Tb09.160.5210 by DGPI v2.04 with cleavage site probability 3.7410002 near 117
RNA pseudouridylate synthase protein, putative
weakly similar to Ribosomal large subunit pseudouridine synthase D (EC 4.2.1.70)(Pseudouridylate synthase) (Uracil hydrolyase) (Swiss-Prot:P33640) (Pseudomonas aeruginosa)
contains mitochrondrial ribosomal protein RPS47 domain
adenosine monophosphate deaminase, putative
similar to AMP deaminase 2 (EC 3.5.4.6) (AMP deaminase isoform L) (Swiss-Prot:Q01433) (Homo sapiens)
similarity to 2-enoyl thioester reductase {Bos taurus} and nuclear receptor-binding factor 1 {Homo sapiens}
ADP-ribosylation factor-like protein, putative
variant surface glycoprotein (VSG, pseudogene), putative; degenerate fragment
GPI-Anchor Signal predicted for Tb09.160.5380 by DGPI v2.04, no cleavage site predicted
GPI-Anchor Signal predicted for Tb09.160.5390 by DGPI v2.04 with cleavage site probability 0.15599999 near 448
GPI-Anchor Signal predicted for Tb09.160.5430 by DGPI v2.04 with cleavage site probability 1.72 near 238
GPI-Anchor Signal predicted for Tb09.v1.0290 by DGPI v2.04 with cleavage site probability 0.172 near 349
GPI-Anchor Signal predicted for Tb09.v1.0300 by DGPI v2.04 with cleavage site probability 0.24939999 near 353
GPI-Anchor Signal predicted for Tb09.v1.0310 by DGPI v2.04 with cleavage site probability 0.172 near 332
GPI-Anchor Signal predicted for Tb09.v1.0320 by DGPI v2.04 with cleavage site probability 0.15599999 near 448
GPI-Anchor Signal predicted for Tb09.v1.0330 by DGPI v2.04 with cleavage site probability 0.25800002 near 242
GPI-Anchor Signal predicted for Tb09.160.5440 by DGPI v2.04 with cleavage site probability 0.172 near 349
GPI-Anchor Signal predicted for Tb09.160.5520 by DGPI v2.04 with cleavage site probability 0.24939999 near 82
calpain-like cysteine peptidase, putative
possible role in intracellular trafficking (curated by Mark Field)
GPI-Anchor Signal predicted for Tb09.v1.0450 by DGPI v2.04 with cleavage site probability 0.78000003 near 278
similar to Structural maintenance of chromosome 2 (Chromosome-associated proteinE) (Chromosome assembly protein XCAP-E). (Swiss-Prot:P50533) (Xenopus laevis)
similar over 163aa to Tropomyosin 1 (Swiss- Prot:P17536) (Saccharomyces cerevisiae)
GPI-Anchor Signal predicted for Tb09.v1.0500 by DGPI v2.04 with cleavage site probability 0.78000003 near 286
GPI-Anchor Signal predicted for Tb09.v1.0530 by DGPI v2.04 with cleavage site probability 0.78000003 near 286
GPI-Anchor Signal predicted for Tb09.211.0010 by DGPI v2.04 with cleavage site probability 0.78000003 near 284
ubiquitin-conjugating enzyme E2, putative
similar to Vegetative cell wall protein gp1 precursor (Hydroxyproline-richglycoprotein 1). (Swiss- Prot:Q9FPQ6) (Chlamydomonas reinhardtii;)
nascent polypeptide associated complex subunit, putative
sequence similarity to pescadillo protein
cytochrome c oxidase assembly factor, putative
GPI-Anchor Signal predicted for Tb09.211.0550 by DGPI v2.04, no cleavage site predicted
similar to SP:P12432: Actin A. {Trypanosoma brucei brucei;} PMID:3386635
GPI-Anchor Signal predicted for Tb09.211.0640 by DGPI v2.04 with cleavage site probability 1.462 near 96
GPI-Anchor Signal predicted for Tb09.211.0650 by DGPI v2.04, no cleavage site predicted
isopentenyl-diphosphate delta-isomerase, putative
developmentally regulated GTP-binding protein, putative
GPI-Anchor Signal predicted for Tb09.211.0750 by DGPI v2.04, no cleavage site predicted
tRNA (guanine-N(7)-)-methyltransferase, putative
GPI-Anchor Signal predicted for Tb09.211.0820 by DGPI v2.04 with cleavage site probability 0.1224 near 592
polyadenylate-binding protein 1, putative
phosphatidylcholine:ceramide cholinephosphotransferase 2, putative
similar to Phosphatidylcholine:ceramide cholinephosphotransferase 2 (EC 2.7.-.-)(Sphingomyelin synthase 2). (Swiss-Prot:Q9D4B1) (Mus musculus;)
GPI-Anchor Signal predicted for Tb09.211.1050 by DGPI v2.04, no cleavage site predicted
similar to Tubulin tyrosine ligase-like protein 1(Swiss-Prot:O95922) (Homo sapiens)
minichromosome maintenance complex subunit
similar to DNA replication licensing factor MCM7 (CDC47 homolog). (Swiss-Prot:Q61881) (Mus musculus;)
DNA recombination/repair protein RAD51/Dmc1
small glutamine rich protein with tetratricopeptide repeats
some similarity to secretory carrier membrane protein 4
peptidyl-prolyl cis-trans isomerase (cyclophilin- 40), putative
GPI-Anchor Signal predicted for Tb09.211.1360 by DGPI v2.04, no cleavage site predicted
glyceraldehyde-3-phosphate dehydrogenase, putative
glycine cleavage system H protein, putative
similar to HSP, ORP140, Calcium binding protein
(curated by B. Wickstead, Univ. of Oxford); similar to SP:Q39493: Diatom spindle kinesin 1. {Cylindrotheca fusiformis}
contains WD40 repeats katanin p80-like protein (curated by B. Wickstead, Univ. of Oxford)
small nuclear RNA gene activation protein 50
also known as p57 in Leptomonas seymouri, binds to SL promoter region
dual specificity protein phosphatase, putative
similar to Dual specificity protein phosphatase 9 (EC 3.1.3.48) (EC 3.1.3.16)(Mitogen-activated protein kinase phosphatase 4) (MAP kinasephosphatase 4) (MKP-4). (Swiss-Prot:Q99956) (Homo sapiens;)
some similarity to DNAJ chaparone protein
phosphatidylserine decarboxylase, putative
weak similarity to Telomerase-binding protein p23 (Hsp90 co-chaperone)
weak similarity to Asc-type amino acid transporter 1 (Asc-1) (D-serine transporter). (Swiss-Prot:Q9JMH8) (Mus musculus;Rattus norvegicus;)
DNA polymerase epsilon catalytic subunit, putative
3-demethylubiquinone-9 3-methyltransferase, putative
Model contain Synaptojanin, N-terminal domain, (IPR002013) present in proteins such as the GTPase dynamin, the lysophosphatidic acid acyl transferase endophilin, and the phosphoinositide phosphatase synaptojanin, all involved in the recycling pathway of c
similar to Polyadenylate-binding protein (Poly(A)-binding protein) (PABP) (Swiss-Prot:P21187) (Drosophila melanogaster); similar to Polyadenylate- binding protein 4 (Poly(A)-binding protein 4) (PABP 4)(Inducible poly(A)-binding protein) (iPABP) (S
some similarity to cAMP-dependent protein kinase regulatory subunit
ATP-dependent DEAD/H RNA helicase, putative
protein kinase A catalytic subunit isoform 2
some sequence similarity to mitochondrial carrier protein
GPI-Anchor Signal predicted for Tb09.211.2390 by DGPI v2.04, no cleavage site predicted
protein kinase A catalytic subunit isoform 1
pers. comm. M. Boshart, University of Munich; similar to cAMP-dependent protein kinase catalytic subunit (EC 2.7.1.37). (Swiss-Prot:P34099) (Dictyostelium discoideum;)
GPI-Anchor Signal predicted for Tb09.211.2460 by DGPI v2.04 with cleavage site probability 0.14400001 near 846
GPI-Anchor Signal predicted for Tb09.211.2500 by DGPI v2.04 with cleavage site probability 0.14039999 near 72
similar to T-complex protein 1, eta subunit (TCP-1-eta) (CCT-eta) (HIV-1 Nefinteracting protein). (Swiss-Prot:Q99832) (Homo sapiens); and to T-complex protein 1, eta subunit (TCP-1-eta) (CCT- eta) (HIV-1 Nefinteracting protein). (Swiss-Prot:Q99832) (H
much longer than S17; similar to 30S ribosomal protein S17. (Swiss-Prot:P38519) (Thermotoga maritima;)
similar to 60S ribosomal protein L27a (L29). (Swiss-Prot:O15883) (Trypanosoma brucei brucei)
similar to 60S ribosomal protein L27a (L29). (Swiss-Prot:O15883) (Trypanosoma brucei brucei) similar to 60S ribosomal protein L27a (L29). (Swiss- Prot:O15883) (Trypanosoma brucei brucei)
similar to Anaphase promoting complex subunit 2 (APC2) from mouse
GPI-Anchor Signal predicted for Tb09.211.2750 by DGPI v2.04 with cleavage site probability 0.344 near 217
iron-sulfur cluster assembly protein, putative
similar to Peptidyl-prolyl cis-trans isomerase 10 (EC 5.2.1.8) (PPIase)(Rotamase) (Cyclophilin-10). (Swiss-Prot:P52017) (Caenorhabditis elegans;)
probably integral membrane protein, contains MATE efflux family protein domain
probably integral membrance protein, contains MATE efflux family protein domain
similarity to probable phosphoglyceride transfer protein from Arabidopsis thaliana
structural maintenance of chromosome 1, putative
similar to Structural maintenance of chromosome 1 (Cohesin complex subunit psm1)(Chromosome segregation protein smc1). (Swiss-Prot:O94383) (Schizosaccharomyces pombe); similar to Structural maintenance of chromosome 1- like 1 protein (SMC1alphaprotein
similar over 81aa in zinc finger region to Early endosome antigen 1 (Endosome-associated protein p162). (Swiss-Prot:Q15075) (Homo sapiens); UniProt:Q18930 kinase anchor protein {Caenorhabditis elegans}
6-phosphogluconate dehydrogenase decarboxylating
weak similarity to ATP synthase a chain (EC 3.6.3.14) (ATPase protein 6). (Swiss-Prot:P24499) (Trypanosoma brucei brucei;)
GPI-Anchor Signal predicted for Tb09.211.3330 by DGPI v2.04, no cleavage site predicted
GPI-Anchor Signal predicted for Tb09.211.3340 by DGPI v2.04 with cleavage site probability 1.026 near 147
similar to Ubiquitin-activating enzyme E1 2 (Swiss-Prot:P31251) (Triticum aestivum)
prenyl protein specific carboxyl methyltransferase
poly(ADP-ribose) glycohydrolase, putative
similar to T complex testis-specific protein 2 (TCTEX-2) (Swiss-Prot:P11985) (Mus musculus;); simlar to GB:AAB58383.1: outer arm dynein light chain, 19K {Chlamydomonas reinhardtii}
similar to Cysteine desulfurase (EC 2.8.1.7) (Nitrogenase metalloclustersbiosynthesis protein nifS). (Swiss-Prot:Q43884) (Anabaena azollae); similar to Cysteine desulfurase, mitochondrial precursor (EC 2.8.1.7) (HUSSY-08). (Swiss-Prot:Q9Y697) (Hom
GPI-Anchor Signal predicted for Tb09.211.4050 by DGPI v2.04 with cleavage site probability 0.124699995 near 81
GPI-Anchor Signal predicted for Tb09.211.4070 by DGPI v2.04 with cleavage site probability 0.64599997 near 160
NADPH--cytochrome p450 reductase, putative
similar to NADPH--cytochrome P450 reductase (EC 1.6.2.4) (CPR) (P450R). (Swiss-Prot:P37039) (Cavia porcellus)
GPI-Anchor Signal predicted for Tb09.211.4155 by DGPI v2.04 with cleavage site probability 0.12900001 near 68
similar to Thyroid receptor interacting protein 12 (TRIP12). (Swiss-Prot:Q14669) (Homo sapiens;); similar over 1679aa to HECT ubiquitin-protein ligase 3 (GB:AAP91821.1) (Arabidopsis thaliana)
phosphoinositide-binding protein, putative
GPI-Anchor Signal predicted for Tb09.211.4420 by DGPI v2.04 with cleavage site probability 0.124699995 near 80
vesicle-associated membrane protein, putative
GPI-Anchor Signal predicted for Tb09.211.4690 by DGPI v2.04 with cleavage site probability 0.4644 near 190
reiske iron-sulfur protein mitochondrial precursor
similar to Ubiquinol-cytochrome c reductase iron-sulfur subunit 3, mitochondrialprecursor (EC 1.10.2.2) (Rieske iron-sulfur protein 3) (RISP3). (Swiss- Prot:P51133) (Nicotiana tabacum)
GPI-Anchor Signal predicted for Tb09.211.4710 by DGPI v2.04 with cleavage site probability 0.76 near 635
GPI-Anchor Signal predicted for Tb09.211.4790 by DGPI v2.04 with cleavage site probability 0.64800006 near 65
RNA 3'-terminal phosphate cyclase-like protein
many of residues required for catalytic activty and cyclosporin A binding are not present; similar to Peptidyl-prolyl cis-trans isomerase 2 (EC 5.2.1.8) (PPIase) (Rotamase)(Cyclophilin-2). (Swiss-Prot:P52010) (Caenorhabditis elegans)
GPI-Anchor Signal predicted for Tb09.211.4940 by DGPI v2.04, no cleavage site predicted
leucine-rich repeat protein (LRRP, pseudogene), putative
iron/ascorbate oxidoreductase family protein, putative
hit to pfam:PF03171, 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily
collapsed repeat - exact copy number not resolved
truncated; corresponds to C-terminal half of ORF2
partial blastn hit to retrotransposable 5096..6323 score: 2248 percent id: 99.00 element SLACS (embl:X17078)
DNA polymerase epsilon subunit B, putative
trypanin-related protein: pers. comm. K. Hill, UCLA
GPI-Anchor Signal predicted for Tb09.244.2610 by DGPI v2.04 with cleavage site probability 0.74819994 near 89
ungrouped kinesin (curated by B. Wickstead, Univ. of Oxford)
ADP-ribosylation factor GTPase activating protein, putative
similar to ADP-ribosylation factor GTPase- activating protein 3 (ARF GAP 3). (Swiss-Prot:Q9NP61) (Homo sapiens;)
bloodstream stage alanine-rich protein BARP
GPI-Anchor Signal predicted for Tb09.244.2530 by DGPI v2.04 with cleavage site probability 0.51600003 near 275
GPI-Anchor Signal predicted for Tb09.244.2520 by DGPI v2.04 with cleavage site probability 0.51600003 near 239
GPI-Anchor Signal predicted for Tb09.244.2510 by DGPI v2.04 with cleavage site probability 0.51600003 near 239
GPI-Anchor Signal predicted for Tb09.244.2500 by DGPI v2.04 with cleavage site probability 0.51600003 near 269
GPI-Anchor Signal predicted for Tb09.244.2490 by DGPI v2.04 with cleavage site probability 0.51600003 near 269
GPI-Anchor Signal predicted for Tb09.244.2480 by DGPI v2.04 with cleavage site probability 0.702 near 234
GPI-Anchor Signal predicted for Tb09.244.2470 by DGPI v2.04 with cleavage site probability 0.51600003 near 257
GPI-Anchor Signal predicted for Tb09.244.2460 by DGPI v2.04 with cleavage site probability 0.702 near 234
GPI-Anchor Signal predicted for Tb09.244.2450 by DGPI v2.04 with cleavage site probability 0.696 near 306
GPI-Anchor Signal predicted for Tb09.244.2440 by DGPI v2.04 with cleavage site probability 0.51600003 near 239
GPI-Anchor Signal predicted for Tb09.244.2430 by DGPI v2.04 with cleavage site probability 0.51600003 near 239
GPI-Anchor Signal predicted for Tb09.244.2420 by DGPI v2.04 with cleavage site probability 0.702 near 233
GPI-Anchor Signal predicted for Tb09.244.2410 by DGPI v2.04 with cleavage site probability 0.51600003 near 240
GPI-Anchor Signal predicted for Tb09.244.2400 by DGPI v2.04 with cleavage site probability 0.51600003 near 239
GPI-Anchor Signal predicted for Tb09.244.2390 by DGPI v2.04 with cleavage site probability 2.3220003 near 323
GPI-Anchor Signal predicted for Tb09.244.2360 by DGPI v2.04, no cleavage site predicted
expression site-associated gene 6 (ESAG6, pseudogene), putative
GPI-Anchor Signal predicted for Tb09.v1.0840 by DGPI v2.04, no cleavage site predicted
GPI-Anchor Signal predicted for Tb09.244.2140 by DGPI v2.04, no cleavage site predicted
GPI-Anchor Signal predicted for Tb09.v1.0860 by DGPI v2.04 with cleavage site probability 0.442 near 36
expression site-associated gene 4 (ESAG4, pseudogene), putative; fragment
leucine-rich repeat protein (LRRP, pseudogene), putative; similar to C-terminal half of LRRP1; frameshifted
leucine-rich repeat protein (pseudogene), putative; fragment from near N-terminus of LRRP1
variant surface glycoprotein (VSG, pseudogene), putative; truncated at N-terminus; contains 1 frameshift
variant surface glycoprotein (VSG, pseudogene), putative; pers. comm. L. Marcello, Univ. of Glasgow.
variant surface glycoprotein (VSG, pseudogene), putative; frameshifted and point-mutated fragment
variant surface glycoprotein (VSG, pseudogene), putative; truncated at C-terminus; possible insertion after codon 144
variant surface glycoprotein (VSG, pseudogene), putative; in-frame stop after codon 352
GPI-Anchor Signal predicted for Tb09.244.1830 by DGPI v2.04 with cleavage site probability 1.653 near 478
variant surface glycoprotein (VSG, pseudogene), putative; vsg fragment, truncated at both ends - one end due to ingi insertion
GPI-Anchor Signal predicted for Tb09.244.1790 by DGPI v2.04, no cleavage site predicted
expression site-associated gene 3 (ESAG3, pseudogene), putative
variant surface glycoprotein (VSG, pseudogene), putative; possible vsg pseudogene; truncated to 417 aa by two in-frame stop codons
variant surface glycoprotein (VSG, pseudogene), putative; pers. comm. L. Marcello, Univ. of Glasgow. interrupted by INGI downstream
hit to RIME_A 3..253 score: 381 percent id: 94.00 from 1..253 of TBINGIC_3 (M16068)
2 frameshifts and an internal stop codon
half of RIME_B (1..121) score: 208 percent id: 97.00 4951..5204 from TBINGIC, 254 BP
variant surface glycoprotein (VSG, pseudogene), putative; C-terminal vsg fragment
variant surface glycoprotein (VSG, pseudogene), putative; vsg with at least one frameshift and internal stop codon; position of frameshift uncertain
variant surface glycoprotein (VSG, pseudogene), putative; contains several internal stop codons
variant surface glycoprotein (VSG, pseudogene), putative; contains 1 frameshift
variant surface glycoprotein (VSG, pseudogene), putative; contains internal stop codon
ingi fragment; truncated by insertion of another ingi element
hit to RIME_B 243..1 score: 377 percent id: 94.00 4951..5204 from TBINGIC, 254 BP
hit to RIME A 5..253 score: 345 percent id: 93.00, 1..253 of TBINGIC_3 (M16068)
hit to RIME_B 1..243 score: 373 percent id: 93.00 4951..5204 from TBINGIC, 254 BP
weak similarity to ingi protein 1 (orf1) and weak Pfam hit to rev. transcriptase domain; possibly truncated at N-terminus
variant surface glycoprotein (VSG, pseudogene), putative; contains 1 frameshift and an internal stop codon
hit to RIME_A 6..253 score: 396 percent id: 95.00 from 1..253 of TBINGIC_3 (M16068)
hit to RIME_B 13..243 score: 361 percent id: 94.00 4951..5204 from TBINGIC, 254 BP
GPI-Anchor Signal predicted for Tb09.244.1600 by DGPI v2.04 with cleavage site probability 0.75399995 near 490
variant surface glycoprotein (VSG, pseudogene), putative; degenerate vsg pseudo gene. Exact postion of framshifts not clear
GPI-Anchor Signal predicted for Tb09.244.1580 by DGPI v2.04 with cleavage site probability 0.75399995 near 527
variant surface glycoprotein (VSG, pseudogene), putative; contains 1 frameshift and 1 internal stop codon
variant surface glycoprotein (VSG, pseudogene), putative; contains 2 internal stop codons
variant surface glycoprotein (VSG, pseudogene), putative; truncated at N- and C-termini
variant surface glycoprotein (VSG, pseudogene), putative; truncated vsg
variant surface glycoprotein (VSG, pseudogene), putative; frameshifted
expression site-associated gene 3 (ESAG3, pseudogene), putative; degenerate and frameshifted fragment
variant surface glycoprotein (VSG, pseudogene), putative; formerly vsg fragment and hypothetical protein; merged to vsg pseudogene
variant surface glycoprotein (VSG, pseudogene), putative; interrupted by an ingi
degenerate RIME A monomer. Two halves of monomer seperated by approx. 20 bases. blastn hit to RIME_A 108..22 score: 125 percent id: 93.00 from 1..253 of TBINGIC_3 (M16068); blastn hit to RIME_A 253..128 score: 202 percent id: 95.00 from 1..253 of TBINGIC_3 (M16068)
blastx hit to Q8WPT3 1657..0 score: 261 percent id: 90.00 Q8WPT3 CAD21861.1 Desc: H25N7.04 protein.
variant surface glycoprotein (VSG, pseudogene), putative; pers. comm. L. Marcello, Univ. of Glasgow. same sequence as VSG fragment on the other side of INGI
GPI-Anchor Signal predicted for Tb09.244.1410 by DGPI v2.04 with cleavage site probability 0.75399995 near 503
expression site-associated gene 3 (ESAG3, pseudogene), putative; degenerate and frameshifted
variant surface glycoprotein (VSG, pseudogene), putative; possible vsg fragment
blastn hit to RIME_A 22..108 score: 125 percent id: 93.00 from 1..253 of TBINGIC_3 (M16068); hit to RIME_A 128..253 score: 202 percent id: 95.00 from 1..253 of TBINGIC_3 (M16068)
blastn hit to RIME_B 1..244 score: 420 percent id: 97.00 4951..5204 from TBINGIC, 254 BP
variant surface glycoprotein (VSG, pseudogene), putative; degenerate vsg fragment
hypothetical protein, conserved (pseudogene); degenerate vsg
expression site-associated gene 3 (ESAG3, pseudogene), putative; highly degenerate
expression site-associated gene 3 (ESAG3, pseudogene), putative; degenerate and frameshifted fragment (curated by L. Marcello, Univ. of Glasgow)
GPI-Anchor Signal predicted for Tb09.v1.0900 by DGPI v2.04, no cleavage site predicted
variant surface glycoprotein (VSG, pseudogene), putative; fragment interrupted by an ingi
hit to RIME_B 1..251 score: 402 percent id: 95.00 4951..5204 from TBINGIC, 254 BP
GPI-Anchor Signal predicted for Tb09.244.1000 by DGPI v2.04 with cleavage site probability 0.75399995 near 458
variant surface glycoprotein (VSG, pseudogene), putative; complement(join(2540280..2541422,2541424..2541822))
expression site-associated gene 3 (ESAG3, pseudogene), putative; hit to Q26747 28..96 score: 74 percent id: 52.00 (from M22769), ESAG3 (formerly ESAG2, vsg precursor) Kooter J.M., Winter A.J., de Oliveira C., Wagter R., Borst P., 183aa
GPI-Anchor Signal predicted for Tb09.244.0910 by DGPI v2.04 with cleavage site probability 0.344 near 493
degenerate pseudogene with similarity to ingi protein 1(ORF1) and rev. transcriptase
hit to RIME_A 6..237 score: 373 percent id: 95.00 from 1..253 of TBINGIC_3 (M16068)
hit to RIME_B 1..243 score: 387 percent id: 95.00 4951..5204 from TBINGIC, 254 BP
hit to RIME_B 242..1 score: 379 percent id: 94.00 4951..5204 from TBINGIC, 254 BP
hit to RIME_A 237..7 score: 387 percent id: 96.00 from 1..253 of TBINGIC_3 (M16068)
expression site-associated gene 3 (ESAG3, pseudogene), putative; frameshifted and point-mutated fragment
lytic factor resistance-like protein (VSRA, pseudogene), putative; frameshifted and point mutation
GPI-Anchor Signal predicted for Tb09.244.0640 by DGPI v2.04, no cleavage site predicted
variant surface glycoprotein (VSG, pseudogene), putative; blastx hit to Q968L2 456..0 score: 50 percent id: 21.00 Q968L2 Desc: Variable surface glycoprotein
expression site-associated gene 3 (ESAG3, pseudogene), putative; degenerate
hit to RIME_A 253..86 score: 285 percent id: 96.00 from 1..253 of TBINGIC_3 (M16068)
GPI-Anchor Signal predicted for Tb09.244.0510 by DGPI v2.04 with cleavage site probability 3.7410002 near 83
GPI-Anchor Signal predicted for Tb09.244.0470 by DGPI v2.04 with cleavage site probability 0.76 near 513
hit to RIME_B 243..1 score: 387 percent id: 95.00 4951..5204 from TBINGIC, 254 BP
hypothetical protein, conserved, frameshifted fragment, pseudogene; frameshifted fragment
hit to RIME_A 11..251 score: 375 percent id: 95.00 from 1..253 of TBINGIC_3 (M16068)
variant surface glycoprotein (VSG, pseudogene), putative; join(2745369..2745452,2745454..2745898)
expression site-associated gene 3 (ESAG3, pseudogene), putative; frameshifted and degenerate fragment
GPI-Anchor Signal predicted for Tb09.v1.0970 by DGPI v2.04 with cleavage site probability 0.20879999 near 131
truncated at N-terminal end and frameshifted
hit to RIME_B 1..244 score: 379 percent id: 94.00 4951..5204 from TBINGIC, 254 BP
GPI-Anchor Signal predicted for Tb09.244.0050 by DGPI v2.04 with cleavage site probability 0.344 near 480
hit to RIME_A 6..251 score: 385 percent id: 95.00 from 1..253 of TBINGIC_3 (M16068)