Hepatitis C virus genotype 7, complete genome.
type: Entry
definition: Hepatitis C virus genotype 7, complete genome.
sequence version: NC_030791.1
sequence date: 2019-05-28
sequence: sequence
division: VRL
label: NC_030791.1
type: RefSeq
SIO_000068: refseq
dblink: PRJNA485481
keyword: RefSeq
source: Hepatitis C virus genotype 7
organism: Hepatitis C virus genotype 7
taxonomy: Viruses; Riboviria; Flaviviridae; Hepacivirus.
reference: 1
references: 25520447
reference: 2
reference: 3
reference: 4
comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The\nreference sequence is identical to EF108306.\nCOMPLETENESS: full length.

sequence
subclass of: SO_0000353
sequence length: 9443
topology: linear
so has quality: SO_0000987
location: 1..9443
location: region:1-9443:1
RO_0002162: 1544901

NC_030791
type: RefSeq
SIO_000068: refseq

PRJNA485481
type: BioProject
SIO_000068: bioproject

1
title: Hepatitis C virus genotype 7, a new genotype originating from central Africa
author: Murphy, D.G.
author: Sablon, E.
author: Chamberland, J.
author: Fournier, E.
author: Dandavino, R.
author: Tremblay, C.L.
journal: J. Clin. Microbiol.
volume: 53
issue: 3
pages: 967-972
year: 2015
pubmed: 25520447

25520447
type: PubMed
SIO_000068: pubmed

2
title: Direct Submission
journal: Submitted (19-AUG-2016) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA

3
title: Direct Submission
author: Murphy, D.
journal: Submitted (03-MAR-2015) Biologie Moleculaire, Laboratoire de Sante Publique du Quebec, Institut National de Sante Publique du Quebec, 20045 Chemin Sainte-Marie, Sainte-Anne-de-Bellevue, Quebec H9X 3R5, Canada
comments: Sequence update by submitter

4
title: Direct Submission
author: Murphy, D.
journal: Submitted (08-NOV-2006) Biologie Moleculaire, Laboratoire de Sante Publique du Quebec, Institut National de Sante Publique du Quebec, 20045 Chemin Sainte-Marie, Sainte-Anne-de-Bellevue, Quebec H9X 3R5, Canada

position:1:1
position: 1
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:9443:1
position: 9443
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

feature:1-9443:1:source
so part of: sequence
organism: Hepatitis C virus genotype 7
mol type: genomic RNA
isolate: QC69
isolation source: plasma
host: Homo sapiens
country: Canada
subtype: 7a
note: emigrant from the Democratic Republic of Congo

1544901
type: Taxonomy
SIO_000068: taxonomy

5'UTR
type: Five Prime UTR
subclass of: SO_0000204
RO_0002162: 1544901
so part of: sequence
location: 1..339
location: region:1-339:1
so has part: feature:1-339:1:region

position:339:1
position: 339
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:1-339:1:region

BFX91_gp1
type: Gene
subclass of: SO_0000704
RO_0002162: 1544901
gene: POLY
locus tag: BFX91_gp1
so part of: sequence
location: 340..9381
location: region:340-9381:1
so has part: feature:340-9381:1:exon
subclass of: SO_0000010

35984104
type: Gene
SIO_000068: ncbigene

position:340:1
position: 340
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:9381:1
position: 9381
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:340-9381:1:exon

BFX91_gp1
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 1544901
gene: POLY
locus tag: BFX91_gp1
codon start: 1
product: polyprotein
translation: MSTNPKPQRLTKRNTVRRPQNVKFPGGGQIVGGVYLLPRRGPRLGVRGTRKSSERSQPRGRRQRIPKAASSQGKAWGKPGYPWPLYGNEGCGWAGWLLSPRGSRPTWGPTDPRHRSRNLGKVIDTMTCGFADLMGYIPVLGAPLGGVARALAHGVRVLEDGVNYATGNLPGCSFSIFLLALLSCLTVPASAYEVRNSSGVYHLTNDCPNASIVYETDNAILHEPGCVPCVREGNTSRCWEPVAPTLAVRYRGALTDDLRTHIDLVVASATLCSALYVGDICGAIFIASQAVLWKPGGGRIVQDCNCSIYPGHVTGHRMAWDMMQNWAPALSMVAAYAVRVPGVIITTVAGGHWGVLFGLAYFGMAGNWAKVILIMLLMSGVDAETMAVGARAAHTTGALVSLLNPGPSQRLQLINTNGSWHINRTALNCNDSLQTGFIAALFYTHRFNSSGCPERMASCKPLSDFDQGWGPLWYNSTERPSDQRPYCWHYAPSPCGIVPAKDVCGPVYCFTPSPVVVGTTDRRGVPTYTWGENESDVFLLNSTRPPQGSWFGCSWMNTTGFTKTCGGPPCKIRPQGAQSNTSLTCPTDCFRKHPRATYSACGSGPWLTPRCMVHYPYRLWHYPCTVNFTIHKVRLYIGGVEHRLDAACNWTRGERCDLEDRDRVDMSPLLHSTTELAILPCSFVPLPALSTGLIHLHQNIVDAQYLYGLSPAIISWAIRWEWVVLVFLLLADARICACLWMMMLMAQAEAALENLIHLNAASLAGTHGIWWLLLVFCASWHLRGRVVPLVTYGICGMWPFFLMLLSLPPRAYALDREVSAALGTGMLAIILLVTLGPHYKRLLALILWWVTYFLTRCEAALQTWVPPLNPRGGRDGFILCVLLCYPGLVFDITKWLLVMMCPLYLLQLCLVRTPYFVRAQALIRVCSLFKTLAGGRYVQAALLTIGRWTGTYIYNHLAPLETWAAGGLRDLAVAVEPVIFSPMEKKIIVWGAETTACGDILCGLPVSARLGREVLLGPADDYRSMGWQLLAPISAYAQQTRGLISTLVVSLTGRDKNETAGEVQVLSTSTQTFLGTNVGGVMWGPYHGAGTRTVAGRGGPVLQMYTSVSDDLVGWPAPPGSKSLEPCSCGSADLYLVTRNADVLPLRRKGDGTASLLSPRPVSSLKGSSGGPVLCPQSHCVGIFRAAVCTRGVAKAVQFVPIEKMQVAQRSPSFSDNSTPPAVPSTYQVGYLHAPTGSGKSTKVPAAYASQGYKVLVLNPSVAATLGFGAYMSKAYGIDPSVRTGARTVTTGAPITYSTYGKFLADGGCSGGAYDIIICDECHAIDATTVVGIGTVLDQAETSGVRLVVLATATPPGSVTVPHPNIEEVALGNDGEIPFYGKAIPLQHIKGGRHLIFCHSKKKCDELAGKLTSLGLTAVAYYRGLDVSVIPTSGDVVVVATDALMTGFTGDFDSVIDCNVAVTQTVDFSLDPTFTIETTTVPQDSVSRSQRRGRTGRGRLGIYRYVSSGERPSGMFDTSVLCECYDLGCSWYELTPSETTTRLRAYLNCPGLPVCQDHLEFWEGVFTGLTHIDAHFLSQTKQEGQNYAYLTAYQATVCARAKAPPPSWDVQWKCLQRLKPLLVGPTPLLYRLGSVTNEVTFTHPITKYIATCMAADLEVTTSTWVIVGGVLAAVAAYCMSTGSVVVVGRVVLGSNVVTAPDREVLYQHFDEMEECSKAPELLKHAQTIGGMFKDKALAVLDTLKPAAQAAVPIVETNFQKVEKLWNQHMWNFISGIQYLAGLSTLPGNPTVASLMAFTASVTSPLATSTTLLVNILGGWFASQLAPPSAATTFVVSGLAGAAVGSVGLGKVLVDVLAGYGAGIAGALVAFKIMSGEVPSTEDLANLLPAILSPGALVVGVVCAAIIKRHTGTSEGVTQWMNRLIAFASRGNHVSPTHYIQDDDASKRVMGILSSLTITSLIKRVLAWAQTDYSAPCAGSWLREVWDWVCMVLSDFASWLK…
SIO_010081: BFX91_gp1
subclass of: SO_0000673
so part of: BFX91_gp1
location: 340..9381
location: region:340-9381:1
so has part: feature:340-9381:1:exon

YP_009272536.1
type: Protein
SIO_000068: ncbiprotein

urn:…
SIO_000300: 1
SIO_000628: feature:340-9381:1:exon

BFX91_gp1
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 1544901
gene: POLY
locus tag: BFX91_gp1
product: core protein
SIO_010081: BFX91_gp1
subclass of: SO_0000673
so part of: BFX91_gp1
location: 340..912
location: region:340-912:1
so has part: feature:340-912:1:exon

YP_009272680.1
type: Protein
SIO_000068: ncbiprotein

position:912:1
position: 912
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:340-912:1:exon

BFX91_gp1
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 1544901
gene: POLY
locus tag: BFX91_gp1
product: E1 protein
SIO_010081: BFX91_gp1
subclass of: SO_0000673
so part of: BFX91_gp1
location: 913..1488
location: region:913-1488:1
so has part: feature:913-1488:1:exon

YP_009272681.1
type: Protein
SIO_000068: ncbiprotein

position:913:1
position: 913
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:1488:1
position: 1488
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:913-1488:1:exon

BFX91_gp1
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 1544901
gene: POLY
locus tag: BFX91_gp1
product: E2 protein
SIO_010081: BFX91_gp1
subclass of: SO_0000673
so part of: BFX91_gp1
location: 1489..2589
location: region:1489-2589:1
so has part: feature:1489-2589:1:exon

YP_009272682.1
type: Protein
SIO_000068: ncbiprotein

position:1489:1
position: 1489
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:2589:1
position: 2589
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:1489-2589:1:exon

BFX91_gp1
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 1544901
gene: POLY
locus tag: BFX91_gp1
product: p7 protein
SIO_010081: BFX91_gp1
subclass of: SO_0000673
so part of: BFX91_gp1
location: 2590..2778
location: region:2590-2778:1
so has part: feature:2590-2778:1:exon

YP_009272683.1
type: Protein
SIO_000068: ncbiprotein

position:2590:1
position: 2590
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:2778:1
position: 2778
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:2590-2778:1:exon

BFX91_gp1
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 1544901
gene: POLY
locus tag: BFX91_gp1
product: NS2 protein
SIO_010081: BFX91_gp1
subclass of: SO_0000673
so part of: BFX91_gp1
location: 2779..3429
location: region:2779-3429:1
so has part: feature:2779-3429:1:exon

YP_009272684.1
type: Protein
SIO_000068: ncbiprotein

position:2779:1
position: 2779
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:3429:1
position: 3429
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:2779-3429:1:exon

BFX91_gp1
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 1544901
gene: POLY
locus tag: BFX91_gp1
product: NS3 protease/helicase
note: NS3 proteinase / ATPase / helicase peptide
SIO_010081: BFX91_gp1
subclass of: SO_0000673
so part of: BFX91_gp1
location: 3430..5322
location: region:3430-5322:1
so has part: feature:3430-5322:1:exon

YP_009272685.1
type: Protein
SIO_000068: ncbiprotein

position:3430:1
position: 3430
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:5322:1
position: 5322
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:3430-5322:1:exon

BFX91_gp1
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 1544901
gene: POLY
locus tag: BFX91_gp1
product: NS4A protein
SIO_010081: BFX91_gp1
subclass of: SO_0000673
so part of: BFX91_gp1
location: 5323..5484
location: region:5323-5484:1
so has part: feature:5323-5484:1:exon

YP_009272686.1
type: Protein
SIO_000068: ncbiprotein

position:5323:1
position: 5323
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:5484:1
position: 5484
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:5323-5484:1:exon

BFX91_gp1
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 1544901
gene: POLY
locus tag: BFX91_gp1
product: NS4B protein
SIO_010081: BFX91_gp1
subclass of: SO_0000673
so part of: BFX91_gp1
location: 5485..6267
location: region:5485-6267:1
so has part: feature:5485-6267:1:exon

YP_009272687.1
type: Protein
SIO_000068: ncbiprotein

position:5485:1
position: 5485
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:6267:1
position: 6267
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:5485-6267:1:exon

BFX91_gp1
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 1544901
gene: POLY
locus tag: BFX91_gp1
product: NS5A protein
SIO_010081: BFX91_gp1
subclass of: SO_0000673
so part of: BFX91_gp1
location: 6268..7605
location: region:6268-7605:1
so has part: feature:6268-7605:1:exon

YP_009272688.1
type: Protein
SIO_000068: ncbiprotein

position:6268:1
position: 6268
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:7605:1
position: 7605
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:6268-7605:1:exon

BFX91_gp1
type: Mature Peptide
subclass of: SO_0000419
RO_0002162: 1544901
gene: POLY
locus tag: BFX91_gp1
product: NS5B RNA-dependent RNA polymerase
note: RdRp
SIO_010081: BFX91_gp1
subclass of: SO_0000673
so part of: BFX91_gp1
location: 7606..9378
location: region:7606-9378:1
so has part: feature:7606-9378:1:exon

YP_009272689.1
type: Protein
SIO_000068: ncbiprotein

position:7606:1
position: 7606
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

position:9378:1
position: 9378
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:7606-9378:1:exon

BFX91_gp1
type: Coding Sequence
subclass of: SO_0000316
RO_0002162: 1544901
gene: POLY
locus tag: BFX91_gp1
ribosomal slippage: true
note: Potential -2/+1 frameshift protein F; position predicted based on homology to protein F in HCV1 RefSeq NC_004102.1; The predicted ribosomal slippage site appears to be mutated in this virus.
codon start: 1
product: protein F
translation: MSTNPKPQRLPKETPSVAHRTLSSRVAGRSLAESTCCRAGALDWVCAALGRVRSDRSPGEDANVSPKLPLHRVKPGASPGTLGPCMVTRAVAGQGGSCPPAALDLLGAPXTPGTARETSVR
SIO_010081: BFX91_gp1
subclass of: SO_0000673
so part of: BFX91_gp1
location: join(340..368,370..706)
location: region:340-706:1
so has part: feature:340-368:1:exon
so has part: feature:370-706:1:exon

YP_009305096.1
type: Protein
SIO_000068: ncbiprotein

position:706:1
position: 706
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:340-368:1:exon

position:368:1
position: 368
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 2
SIO_000628: feature:370-706:1:exon

position:370:1
position: 370
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

3'UTR
type: Three Prime UTR
subclass of: SO_0000205
RO_0002162: 1544901
so part of: sequence
location: 9382..9443
location: region:9382-9443:1
so has part: feature:9382-9443:1:region

position:9382:1
position: 9382
reference: sequence
type: ForwardStrandPosition
type: ExactPosition

urn:…
SIO_000300: 1
SIO_000628: feature:9382-9443:1:region