West Nile virus lineage 2, complete genome.
Viruses; Riboviria; Flaviviridae; Flavivirus.
NS1' of flaviviruses in the Japanese encephalitis virus serogroup is a product of ribosomal frameshifting and plays a role in viral neuroinvasiveness
An infectious clone of the West Nile flavivirus
Submitted (09-SEP-2004) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (01-DEC-2000) University of Virginia Health Sciences Centre, Department of Internal Medicine/GI, Charlottesville, VA 22906
Submitted (03-AUG-1993) Justus-Liebig-Universitat Giessen, Institut fur Virologie, 35392, Giessen, Germany
REVIEWED REFSEQ: This record has been curated by NCBI staff. The\nreference sequence was derived from M12294.\nOn Dec 3, 2000 this sequence version replaced NC_001563.1.\nThe West Nile viral genome consists of a 42S viral RNA. The\namino-terminal ends of the structural proteins were experimentally\ndetermined and annotated in the authors' submission AAA48498 - see\ncorresponding comment there. The (putative) mature peptides that\nwere missing from or conflicting with the authors' annotation have\nbeen added to this RefSeq record by the NCBI staff with the kind\nhelp of Dr. Vladimir Yamshchikov (Southern Research Institute,\nBirmingham, AL USA).\nCOMPLETENESS: full length.
matrix protein precursor; membrane glycoprotein precursor prM
protease; nucleotide triphosphatase; RNA triphosphatase; RNA helicase
nonstructural protein NS5; RNA-dependent RNA polymerase; methyltransferase component of capping enzyme
NS1' protein; transframe fusion protein expressed via programmed ribosomal frameshifting; when frameshifting occurs, cleavage between NS1 and NS2A fails to occur
NS1'; transframe fusion protein expressed via programmed ribosomal frameshifting; when frameshifting occurs, cleavage between NS1 and NS2A fails to occur