Enterobacteria phage alpha3, complete genome.
Viruses; ssDNA viruses; Microviridae; Bullavirinae; Alpha3microvirus.
Nucleotide sequence of the genome of the bacteriophage alpha 3: interrelationship of the genome structure and the gene products with those of the phages, phi X174, G4 and phi K
Complete nucleotide sequence of the Bacteriophage phiK: Interrelationship of the genome structure, the gene products and the host range with those of the phages alpha3, G4 and phiX174
Submitted (01-AUG-2000) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (20-SEP-1991) K.I. Kodaira, Dept of Cell Technology, Chemical and Biochemical Engineering, Faculty of Engineering, Toyama Univ, 3190 Gofuku, Toyama, Toyama 930, JAPAN
REVIEWED REFSEQ: This record has been curated by NCBI staff. The\nreference sequence was derived from X60322.\nCOMPLETENESS: full length.
Protein B is required for the assembly of the basic building block of the Microvirus capsid and is incorporated into the procapsid. Protein B is displaced by the protein J/ssDNA complex during assembly and is therefore not part of the mature virion. Other names: protein B, gpB. Function: morphogenesis.
240 molecules of protein D form an external scaffold required for the formation of Microvirus procapsid. Not present in mature particles. other names: protein D, gpD; function: morphogenesis
Microvirus cell lysis protein is a membrane protein that inhibits MraY, an enzyme required for murein synthesis, and promotes cell lysis in a manner analogous to cell wall synthesis inhibitors like penicillin. A host factor (slyD) is required for stability of protein E. other names: protein E, gpE; function: phage release by lysis
Protein J binds to ssDNA Microvirus genomes and is packaged with the DNA into procapsids. During packaging it displaces the internal scaffold protein. other names: core protein, protein J; function: DNA packaging, DNA binding
60 copies of protein F form the icosahedral capsid of Microviruses. other names: protein F, gpF; function: phage structural protein
A total of 60 copies of protein G are present at the 12 vertices with 5-fold symmetry of Microvirus capsids. other names: protein G, gpG; function: phage minor structural protein
One molecule of protein H is located at each of the 12 vertices with 5-fold symmetry. Binds to LPS and is involved in particle adsorption to host cells. Several protein H molecules enter the host cytoplasm with the phage genome. other names: protein H, gpH, DNA pilot protein; function: phage minor structural protein, adsorption, DNA injection