Saccharomyces paradoxus chromosome XI, complete sequence.
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.

Contrasting evolutionary genome dynamics between domesticated and wild yeasts

Population-level Yeast Reference Genomes

Submitted (28-APR-2020) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA

Submitted (20-JAN-2020) Biotechnology, Delft University of Technology, van der Maasweg 9, Delft, Netherlands 2629 HZ, Netherlands

Submitted (04-FEB-2017) Institute for Research on Cancer and Aging, Nice (IRCAN), Institute for Research on Cancer and Aging, Nice (IRCAN), 28 Avenue de Valombrose, Nice, PACA 06107, France

PROVISIONAL REFSEQ: This record has not yet been subject to final\nNCBI review. The reference sequence is identical to CP020252.\n\n##Genome-Assembly-Data-START##\nAssembly Date :: 29-JAN-2017\nAssembly Method :: HGAP v. 2.3.0\nAssembly Name :: S. paradoxus CBS432 PacBio Assembly\nGenome Representation :: Full\nExpected Final Version :: Yes\nGenome Coverage :: 112.0x\nSequencing Technology :: PacBio\n##Genome-Assembly-Data-END##\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: INSDC submitter\nAnnotation Status :: Full annotation\nAnnotation Pipeline :: Eukaryotic Annotation Propagation Pipeline\n##Genome-Annotation-Data-END##\nCOMPLETENESS: full length.

culture from neotype of Saccharomyces paradoxus

Protein with similarity to mammalian monocarboxylate permeases; similar to YKL221W

Ferric reductase and cupric reductase; similar to YKL220C

3-hydroxyaspartate dehydratase; similar to YKL218C

Monocarboxylate/proton symporter of the plasma membrane; similar to YKL217W

Dihydroorotate dehydrogenase; similar to YKL216W

Member of the REF (RNA and export factor binding proteins) family; similar to YKL214C

WD repeat protein required for ubiquitin-mediated protein degradation; similar to YKL213C

Phosphatidylinositol phosphate (PtdInsP) phosphatase; similar to YKL212W

Indole-3-glycerol-phosphate synthase; similar to YKL211C

Ubiquitin activating enzyme (E1); similar to YKL210W

Plasma membrane ATP-binding cassette (ABC) transporter; similar to YKL209C

Protein involved in 5' RNA end processing; similar to YKL208W

Member of conserved ER transmembrane complex; similar to YKL207W

Protein involved in 20S proteasome assembly; similar to YKL206C

Nuclear pore protein; similar to YKL205W

eIF4E-associated protein, competes with eIF4G for binding to eIF4E; similar to YKL204W

PIK-related protein kinase and rapamycin target; similar to YKL203C

positive regulator of mannosylphosphate transferase Mnn6p; similar to YKL201C

serine/threonine protein kinase; similar to YKL198C

Vesicle membrane protein (v-SNARE) with acyltransferase activity; similar to YKL196C

Mitochondrial oxidoreductase; similar to YKL195W

Mitochondrial threonyl-tRNA synthetase; similar to YKL194C

Regulatory subunit of the type 1 protein phosphatase (PP1) Glc7p; similar to YKL193C

Mitochondrial matrix acyl carrier protein; similar to YKL192C

Protein required for synthesis of diphthamide; similar to YKL191W

Component of the RAM signaling network; similar to YKL189W

Subunit of a heterodimeric peroxisomal ABC transport complex; similar to YKL188C

Protein required for fatty acid uptake; similar to YKL187C

mRNA transport regulator; similar to YKL186C

Component of the Rpd3L histone deacetylase complex; similar to YKL185W

Ornithine decarboxylase; similar to YKL184W

Beta subunit of fatty acid synthetase; similar to YKL182W

5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase; similar to YKL181W

Ribosomal 60S subunit protein L17A; similar to YKL180W

Golgi membrane protein with similarity to mammalian CASP; similar to YKL179C

Receptor for a factor pheromone; similar to YKL178C

Vacuolar membrane zinc transporter; similar to YKL175W

Protein involved in excretion of putrescine and spermidine; similar to YKL174C

GTPase component of U5 snRNP involved in mRNA splicing via spliceosome; similar to YKL173W

Required for 25S rRNA maturation and 60S ribosomal subunit assembly; similar to YKL172W

Mitochondrial ribosomal protein of the large subunit; similar to YKL170W

serine/threonine protein kinase with unknown cellular role; similar to YKL168C

Mitochondrial ribosomal protein of the large subunit; similar to YKL167C

cAMP-dependent protein kinase catalytic subunit; similar to YKL166C

Protein involved in GPI anchor synthesis; similar to YKL165C

O-glycosylated protein required for cell wall stability; similar to YKL164C

O-glycosylated covalently-bound cell wall protein; similar to YKL163W

Transcription elongation factor with a conserved zinc finger domain; similar to YKL160W

Protein involved in calcineurin regulation during calcium signaling; similar to YKL159C

Aminopeptidase yscII; similar to YKL157W

Protein component of the small (40S) ribosomal subunit; similar to YKL156W

Mitochondrial ribosomal protein of the small subunit; similar to YKL155C

Signal recognition particle (SRP) receptor beta subunit; similar to YKL154W

Tetrameric phosphoglycerate mutase; similar to YKL152C

Mitochondrial NADH-cytochrome b5 reductase; similar to YKL150W

RNA lariat debranching enzyme; similar to YKL149C

Flavoprotein subunit of succinate dehydrogenase; similar to YKL148C

Vacuolar transporter; similar to YKL146W

ATPase of the 19S regulatory particle of the 26S proteasome; similar to YKL145W

RNA polymerase III subunit C25; similar to YKL144C

Component of the GSE complex; similar to YKL143W

Subunit of succinate dehydrogenase and of TIM22 translocase; similar to YKL141W

Steryl ester hydrolase; similar to YKL140W

Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I); similar to YKL139W

Mitochondrial ribosomal protein of the large subunit; similar to YKL138C

Copper-binding protein of the mitochondrial intermembrane space; similar to YKL137W

Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex; similar to YKL135C

Mitochondrial intermediate peptidase; similar to YKL134C

dihydrofolate synthetase; similar to YKL132C

RNA-binding protein that binds specific mRNAs and interacts with She3p; similar to YKL130C

One of two type I myosins; similar to YKL129C

Phosphoglucomutase, minor isoform; similar to YKL127W

Serine/threonine protein kinase; similar to YKL126W

Protein required for transcription of rDNA by RNA polymerase I; similar to YKL125W

Specificity factor required for Rsp5p-dependent ubiquitination; similar to YKL124W

Subunit of the signal recognition particle (SRP); similar to YKL122C

Mitochondrial inner membrane transporter; similar to YKL120W

Integral membrane protein required for V-ATPase function; similar to YKL119C

Co-chaperone that binds and regulates Hsp90 family chaperones; similar to YKL117W

Serine/threonine protein kinase; similar to YKL116C

Major apurinic/apyrimidinic endonuclease; similar to YKL114C

5' to 3' exonuclease, 5' flap endonuclease; similar to YKL113C

DNA binding protein with possible chromatin-reorganizing activity; similar to YKL112W

Protein that plays a role in modification of tRNA wobble nucleosides; similar to YKL110C

Transcription factor; similar to YKL109W

Single-stranded DNA origin-binding and annealing protein; similar to YKL108W

short-chain dehydrogenase/reductase; similar to YKL107W

Mitochondrial aspartate aminotransferase; similar to YKL106W

Glutamine-fructose-6-phosphate amidotransferase; similar to YKL104C

Vacuolar aminopeptidase yscI; similar to YKL103C

Nim1p-related protein kinase; similar to YKL101W

Intramembrane aspartyl protease of the perinuclear ER membrane; similar to YKL100C

Subunit of U3-containing Small Subunit (SSU) processome complex; similar to YKL099C

Cell wall mannoprotein that localizes to birth scars of daughter cells; similar to YKL096W

Essential protein required for pre-mRNA splicing; similar to YKL095W

Monoglyceride lipase (MGL); similar to YKL094W

Protein involved in mitochondrial functions and stress response; similar to YKL093W

GTPase activating factor for Rsr1p/Bud1p; similar to YKL092C

phosphatidylinositol/phosphatidylcholine transfer protein; similar to YKL091C

Protein required for structural integrity of elongating spindles; similar to YKL089W

Subunit of PPCDC and CoA-SPC complexes involved in CoA biosynthesis; similar to YKL088W

Cytochrome c1 heme lyase; similar to YKL087C

Mitochondrial malate dehydrogenase; similar to YKL085W

Zinc-binding mitochondrial intermembrane space (IMS) protein; similar to YKL084W

Essential protein, constituent of 66S pre-ribosomal particles; similar to YKL082C

Gamma subunit of translational elongation factor eEF1B; similar to YKL081W

Subunit C of the V1 peripheral membrane domain of V-ATPase; similar to YKL080W

Kinesin-like myosin passenger-protein; similar to YKL079W

Predominantly nucleolar DEAH-box ATP-dependent RNA helicase; similar to YKL078W

Protein involved in early pre-mRNA splicing; similar to YKL074C

Molecular chaperone of the endoplasmic reticulum lumen; similar to YKL073W

Protein that binds Sin3p in a two-hybrid assay; similar to YKL072W

Methionine-R-sulfoxide reductase; similar to YKL069W

FG-nucleoporin component of central core of the nuclear pore complex; similar to YKL068W

Nucleoside diphosphate kinase; similar to YKL067W

Endoplasmic reticulum transmembrane protein; similar to YKL065C

Vacuolar membrane protein required for magnesium homeostasis; similar to YKL064W

Stress-responsive transcriptional activator; similar to YKL062W

Subunit of the BLOC-1 complex involved in endosomal maturation; similar to YKL061W

Fructose 1,6-bisphosphate aldolase; similar to YKL060C

Essential conserved subunit of CPF cleavage and polyadenylation factor; similar to YKL059C

Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC); similar to YKL057C

Protein that associates with ribosomes; similar to YKL056C

Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase; similar to YKL055C

RNAPII degradation factor; similar to YKL054C

Essential subunit of the Dam1 complex (aka DASH complex); similar to YKL052C

Plasma membrane protein that may act to generate normal levels of PI4P; similar to YKL051W

Centromere protein that resembles histone H3; similar to YKL049C

Serine/threonine protein kinase that regulates cellular morphogenesis; similar to YKL048C

Subunit of DNA primase; similar to YKL045W

Transcriptional activator that enhances pseudohyphal growth; similar to YKL043W

Central plaque component of spindle pole body (SPB); similar to YKL042W

One of four subunits of the ESCRT-III complex; similar to YKL041W

Protein involved in iron metabolism in mitochondria; similar to YKL040C

Glucose-responsive transcription factor; similar to YKL038W

UDP-glucose pyrophosphorylase (UGPase); similar to YKL035W

Subunit of the DSC ubiquitin ligase complex; similar to YKL034W

Subunit of the ASTRA complex, involved in chromatin remodeling; similar to YKL033W

Transcriptional repressor that regulates hypoxic genes during normoxia; similar to YKL032C

Mitochondrial malic enzyme; similar to YKL029C

tRNA threonylcarbamoyladenosine dehydratase; similar to YKL027W

Phospholipid hydroperoxide glutathione peroxidase; similar to YKL026C

Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex; similar to YKL025C

Subunit of the anaphase-promoting complex/cyclosome (APC/C); similar to YKL022C

ER membrane protein involved in regulation of OLE1 transcription; similar to YKL020C

Alpha subunit of farnesyltransferase and geranylgeranyltransferase-I; similar to YKL019W

Subunit of the COMPASS (Set1C) histone H3K4 methyltransferase complex; similar to YKL018W

Hexameric DNA polymerase alpha-associated DNA helicase A; similar to YKL017C

Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase; similar to YKL016C

Transcriptional activator; similar to YKL015W

Protein required for the normal accumulation of 25S and 5.8S rRNAs; similar to YKL014C

Subunit of the ARP2/3 complex; similar to YKL013C

U1 snRNP protein involved in splicing; similar to YKL012W

Mitochondrial cruciform cutting endonuclease; similar to YKL011C

Ubiquitin-protein ligase (E3); similar to YKL010C

Protein involved in mRNA turnover and ribosome assembly; similar to YKL009W

Ceramide synthase component; similar to YKL008C

Alpha subunit of the capping protein heterodimer (Cap1p and Cap2p); similar to YKL007W

Ribosomal 60S subunit protein L14A; similar to YKL006W

Negative regulator of transcription elongation; similar to YKL005C

Phosphatidylinositol:ceramide phosphoinositol transferase; similar to YKL004W

Mitochondrial ribosomal protein of the small subunit; similar to YKL003C

Class E Vps protein of the ESCRT-III complex; similar to YKL002W

Adenylylsulfate kinase; similar to YKL001C

Dynamin-like GTPase required for vacuolar sorting; similar to YKR001C

Member of an oxysterol-binding protein family; similar to YKR003W

Mitochondrial ribosomal protein of the large subunit; similar to YKR006C

Component of the EGO and GSE complexes; similar to YKR007W

Component of the RSC chromatin remodeling complex; similar to YKR008W

3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase; similar to YKR009C

Protein required for rDNA silencing and mitotic rDNA condensation; similar to YKR010C

Endosomal Rab family GTPase; similar to YKR014C

Component of the MICOS complex; similar to YKR016W

RING finger ubiquitin ligase (E3); similar to YKR017C

EH domain-containing protein; similar to YKR019C

Component of the GARP (Golgi-associated retrograde protein) complex; similar to YKR020W

Alpha arrestin, substrate of calcineurin; similar to YKR021W

Essential protein that forms a dimer with Ntr1p; similar to YKR022C

ATP-dependent RNA helicase of the DEAD-box family; similar to YKR024C

RNA polymerase III subunit C37; similar to YKR025W

Alpha subunit of translation initiation factor eIF2B; similar to YKR026C

Member of the ChAPs (Chs5p-Arf1p-binding proteins) family; similar to YKR027W

Protein that forms a complex with the Sit4p protein phosphatase; similar to YKR028W

Defining member of the SET3 histone deacetylase complex; similar to YKR029C

Negative regulator of genes in multiple nitrogen degradation pathways; similar to YKR034W

WD40 repeat-containing protein associated with the CCR4-NOT complex; similar to YKR036C

Essential subunit of the Dam1 complex (aka DASH complex); similar to YKR037C

ATPase of HSP70/DnaK family; similar to YKR038C

General amino acid permease; similar to YKR039W

Mitochondrial inner membrane protein; similar to YKR042W

Sedoheptulose bisphosphatase involved in riboneogenesis; similar to YKR043C

redox protein containing a thioredoxin fold; similar to YKR049C

Component of the Trk1p-Trk2p potassium transport system; similar to YKR050W

Iron transporter of the mitochondrial carrier family; similar to YKR052C

Dihydrosphingosine 1-phosphate phosphatase; similar to YKR053C

Cytoplasmic heavy chain dynein; similar to YKR054C

Non-essential small GTPase; similar to YKR055W

tRNA methyltransferase; similar to YKR056W

Protein component of the small (40S) ribosomal subunit; similar to YKR057W

Glycogenin glucosyltransferase; similar to YKR058W

Translation initiation factor eIF4A; similar to YKR059W

subunit of U3-containing 90S preribosome complex; similar to YKR060W

Mannosyltransferase involved in N-linked protein glycosylation; similar to YKR061W

Protein required for pre-rRNA processing at both ends of ITS2; similar to YKR063C

transcriptional repressor with Zn(2)-Cys(6) finger; similar to YKR064W

Constituent of the TIM23 complex; similar to YKR065C

Mitochondrial cytochrome-c peroxidase; similar to YKR066C

Glycerol-3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase; similar to YKR067W

Core component of transport protein particle (TRAPP) complexes I-III; similar to YKR068C

S-adenosyl-L-methionine uroporphyrinogen III transmethylase; similar to YKR069W

Component of the cytosolic Fe-S protein assembly (CIA) machinery; similar to YKR071C

Negative regulatory subunit of protein phosphatase 1 (Ppz1p); similar to YKR072C

Omega class glutathione transferase; similar to YKR076W

transcriptional activator; similar to YKR077W

tRNA 3'-end processing endonuclease tRNase Z; similar to YKR079C

NAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase; similar to YKR080W

Essential protein involved in rRNA maturation and ribosomal assembly; similar to YKR081C

Subunit of Nup84p subcomplex of nuclear pore complex (NPC); similar to YKR082W

Essential subunit of the Dam1 complex (aka DASH complex); similar to YKR083C

GTPase with similarity to translation release factors; similar to YKR084C

Mitochondrial ribosomal protein of the large subunit; similar to YKR085C

DEAH-box RNA helicase involved in second catalytic step of splicing a; similar to YKR086W

Metalloendopeptidase of the mitochondrial inner membrane; similar to YKR087C

Integral membrane protein; similar to YKR088C

Multifunctional lipase/hydrolase/phospholipase; similar to YKR089C

Protein that localizes to sites of polarized growth; similar to YKR090W

GTB motif (G1/S transcription factor binding) containing protein; similar to YKR091W

Nucleolar serine-rich protein; similar to YKR092C

Integral membrane peptide transporter; similar to YKR093W

Myosin-like protein associated with the nuclear envelope; similar to YKR095W

Phosphoenolpyruvate carboxykinase; similar to YKR097W

Ubiquitin-specific protease; similar to YKR098C

Myb-related transcription factor; similar to YKR099W

Transmembrane protein with a role in cell wall polymer composition; similar to YKR100C

Protein involved in silencing at mating-type loci HML and HMR; similar to YKR101W

Member of the FLO family of cell wall flocculation proteins; similar to YKR102W

transporter of the MRP subfamily; similar to YKR103W

Plasma membrane protein of the Major Facilitator Superfamily (MFS); similar to YKR105C

Proton:glutathione antiporter; similar to YKR106W