Saccharomyces paradoxus chromosome II, complete sequence.
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.

Contrasting evolutionary genome dynamics between domesticated and wild yeasts

Population-level Yeast Reference Genomes

Submitted (28-APR-2020) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA

Submitted (20-JAN-2020) Biotechnology, Delft University of Technology, van der Maasweg 9, Delft, Netherlands 2629 HZ, Netherlands

Submitted (04-FEB-2017) Institute for Research on Cancer and Aging, Nice (IRCAN), Institute for Research on Cancer and Aging, Nice (IRCAN), 28 Avenue de Valombrose, Nice, PACA 06107, France

PROVISIONAL REFSEQ: This record has not yet been subject to final\nNCBI review. The reference sequence is identical to CP020243.\n\n##Genome-Assembly-Data-START##\nAssembly Date :: 29-JAN-2017\nAssembly Method :: HGAP v. 2.3.0\nAssembly Name :: S. paradoxus CBS432 PacBio Assembly\nGenome Representation :: Full\nExpected Final Version :: Yes\nGenome Coverage :: 112.0x\nSequencing Technology :: PacBio\n##Genome-Assembly-Data-END##\n\n##Genome-Annotation-Data-START##\nAnnotation Provider :: INSDC submitter\nAnnotation Status :: Full annotation\nAnnotation Pipeline :: Eukaryotic Annotation Propagation Pipeline\n##Genome-Annotation-Data-END##\nCOMPLETENESS: full length.

culture from neotype of Saccharomyces paradoxus

aryl-alcohol dehydrogenase; similar to YCR107W

zinc cluster transcription factor; similar to YCR106W

NADPH-dependent medium chain alcohol dehydrogenase; similar to YCR105W

Protein with roles in exocytosis and cation homeostasis; similar to YBL106C

Protein serine/threonine kinase; similar to YBL105C

Subunit of the SEA (Seh1-associated) complex; similar to YBL104C

bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways; similar to YBL103C

Tetra-spanning membrane protein found mostly in the late Golgi; similar to YBL102W

Protein involved in regulating endocytosis of plasma membrane proteins; similar to YBL101C

Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase; similar to YBL099W

Kynurenine 3-mono oxygenase; similar to YBL098W

Subunit of the condensin complex; similar to YBL097W

Subunit of the RNA polymerase II mediator complex; similar to YBL093C

Ribosomal 60S subunit protein L32; similar to YBL092W

Methionine aminopeptidase; similar to YBL091C

Mitochondrial ribosomal protein of the small subunit; similar to YBL090W

Protein kinase primarily involved in telomere length regulation; similar to YBL088C

Protein implicated in polar growth; similar to YBL085W

Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C); similar to YBL084C

Dolichol-P-Man dependent alpha(1-3) mannosyltransferase; similar to YBL082C

Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex; similar to YBL080C

Subunit of the inner ring of the nuclear pore complex (NPC); similar to YBL079W

Component of autophagosomes and Cvt vesicles; similar to YBL078C

Cytoplasmic isoleucine-tRNA synthetase; similar to YBL076C

ATPase involved in protein folding and the response to stress; similar to YBL075C

Component of the U5 snRNP complex; similar to YBL074C

Protein component of the small (40S) ribosomal subunit; similar to YBL072C

Lipid raft associated protein; similar to YBL069W

5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP; similar to YBL068W

Ubiquitin-specific protease that cleaves Ub-protein fusions; similar to YBL067C

transcription factor; similar to YBL066C

Mitochondrial peroxiredoxin with thioredoxin peroxidase activity; similar to YBL064C

Kinesin-related motor protein; similar to YBL063W

Activator of Chs3p (chitin synthase III) during vegetative growth; similar to YBL061C

Guanine nucleotide exchange factor specific for Arf3p; similar to YBL060W

UBX (ubiquitin regulatory X) domain-containing protein; similar to YBL058W

One of two mitochondrially-localized peptidyl-tRNA hydrolases; similar to YBL057C

Type 2C protein phosphatase (PP2C); similar to YBL056W

3'-->5' exonuclease and endonuclease with a possible role in apoptosis; similar to YBL055C

PAC motif binding protein involved in rRNA and ribosome biogenesis; similar to YBL054W

Histone acetyltransferase catalytic subunit of NuA3 complex; similar to YBL052C

Protein involved in G2/M phase progression and response to DNA damage; similar to YBL051C

Alpha-SNAP cochaperone; similar to YBL050W

Scaffold protein involved in the formation of early endocytic sites; similar to YBL047C

Regulatory subunit of protein phosphatase PP4; similar to YBL046W

Core subunit of the ubiquinol-cytochrome c reductase complex; similar to YBL045C

High affinity uridine permease, localizes to the plasma membrane; similar to YBL042C

Beta 6 subunit of the 20S proteasome; similar to YBL041W

Major CTP synthase isozyme (see also URA8); similar to YBL039C

Mitochondrial ribosomal protein of the large subunit; similar to YBL038W

non-specific single-domain racemase; similar to YBL036C

B subunit of DNA polymerase alpha-primase complex; similar to YBL035C

Component of the mitotic spindle; similar to YBL034C

GTP cyclohydrolase II; similar to YBL033C

RNA binding protein involved in asymmetric localization of ASH1 mRNA; similar to YBL032W

Mitotic spindle protein; similar to YBL031W

Major ADP/ATP carrier of the mitochondrial inner membrane; similar to YBL030C

Ribosomal 60S subunit protein L19B; similar to YBL027W

Lsm (Like Sm) protein; similar to YBL026W

Protein involved in promoting high level transcription of rDNA; similar to YBL025W

S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase; similar to YBL024W

Protein involved in DNA replication; similar to YBL023C

ATP-dependent Lon protease; similar to YBL022C

Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex; similar to YBL021C

Membrane protein required for translocation of Man5GlcNac2-PP-Dol; similar to YBL020W

Class II abasic (AP) endonuclease involved in repair of DNA damage; similar to YBL019W

Subunit of both RNase MRP and nuclear RNase P; similar to YBL018C

Type I transmembrane sorting receptor for multiple vacuolar hydrolases; similar to YBL017C

Mitogen-activated serine/threonine protein kinase involved in mating; similar to YBL016W

Protein with CoA transferase activity; similar to YBL015W

Component of the core factor (CF) rDNA transcription factor complex; similar to YBL014C

Methionyl-tRNA formyltransferase; similar to YBL013W

Glycerol 3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase; similar to YBL011W

Subunit of the HIR complex; similar to YBL008W

Cytoskeletal protein binding protein; similar to YBL007C

Component of the RSC chromatin remodeling complex; similar to YBL006C

Transcriptional activator of the pleiotropic drug resistance network; similar to YBL005W

Component of the small-subunit (SSU) processome; similar to YBL004W

neutral trehalase, required for thermotolerance; similar to YBR001C

Cis-prenyltransferase involved in dolichol synthesis; similar to YBR002C

Hexaprenyl pyrophosphate synthetase; similar to YBR003W

Protein of the ER membrane involved in cell wall chitin deposition; similar to YBR005W

Succinate semialdehyde dehydrogenase; similar to YBR006W

suppressor of mpt5 mutation; similar to YBR007C

Plasma membrane transporter of the major facilitator superfamily; similar to YBR008C

Cytoplasmic inorganic pyrophosphatase (PPase); similar to YBR011C

Cis-golgi localized monothiol glutaredoxin; similar to YBR014C

Alpha-1,2-mannosyltransferase; similar to YBR015C

Tail-anchored plasma membrane protein with a conserved CYSTM module; similar to YBR016W

Transportin or cytosolic karyopherin beta 2; similar to YBR017C

Galactose-1-phosphate uridyl transferase; similar to YBR018C

UDP-glucose-4-epimerase; similar to YBR019C

Plasma membrane localized uracil permease; similar to YBR021W

Phosphatase that is highly specific for ADP-ribose 1''-phosphate; similar to YBR022W

Protein anchored to mitochondrial inner membrane; similar to YBR024W

P-loop ATPase with similarity to OLA1 and bacterial YchF; similar to YBR025C

2-enoyl thioester reductase; similar to YBR026C

Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase); similar to YBR029C

Ribosomal lysine methyltransferase; similar to YBR030W

Ribosomal 60S subunit protein L4B; similar to YDR012W

zinc cluster protein, predicted to be a transcription factor; similar to YBR033W

Nuclear SAM-dependent mono- and asymmetric methyltransferase; similar to YBR034C

Pyridoxine (pyridoxamine) phosphate oxidase; similar to YBR035C

Endoplasmic reticulum membrane protein; similar to YBR036C

Copper-binding protein of mitochondrial inner membrane; similar to YBR037C

Gamma subunit of the F1 sector of mitochondrial F1F0 ATP synthase; similar to YBR039W

Integral membrane protein required for efficient mating; similar to YBR040W

Very long chain fatty acyl-CoA synthetase and fatty acid transporter; similar to YBR041W

transferase involved in phospholipid biosynthesis; similar to YBR042C

Multidrug transporter of the major facilitator superfamily; similar to YBR043C

Protein involved in assembly of the succinate dehydrogenase complex; similar to YBR044C

Meiosis-specific regulatory subunit of the Glc7p protein phosphatase; similar to YBR045C

NADPH-dependent quinone reductase; similar to YBR046C

Protein component of the small (40S) ribosomal subunit; similar to YDR025W

RNA polymerase I enhancer binding protein; similar to YBR049C

Regulatory subunit of the Glc7p type-1 protein phosphatase; similar to YBR050C

Protein with a role in response to acid stress; similar to YBR054W

glycoside hydrolase of the mitochondrial intermembrane space; similar to YBR056W

Protein essential for meiotic DNA replication and sporulation; similar to YBR057C

Ubiquitin-specific protease; similar to YBR058C

Ser-Thr protein kinase; similar to YBR059C

Subunit of the origin recognition complex (ORC); similar to YBR060C

2'-O-ribose methyltransferase; similar to YBR061C

Pre-mRNA splicing factor; similar to YBR065C

Transcriptional repressor; similar to YBR066C

Major cell wall mannoprotein with possible lipase activity; similar to YBR067C

High-affinity leucine permease; similar to YBR068C

Amino acid transporter for valine, leucine, isoleucine, and tyrosine; similar to YBR069C

Component of UDP-GlcNAc transferase; similar to YBR070C

Small heat shock protein (sHSP) with chaperone activity; similar to YBR072W

DNA-dependent ATPase; similar to YBR073W

Multi-spanning vacuolar membrane protease; similar to YBR074W

Component of the EGO and GSE complexes; similar to YBR077C

eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3); similar to YBR079C

AAA ATPase and SNARE disassembly chaperone; similar to YBR080C

Subunit of the SAGA transcriptional regulatory complex; similar to YBR081C

Ubiquitin-conjugating enzyme (E2); similar to YBR082C

Transcription factor targeting filamentation genes and Ty1 expression; similar to YBR083W

Mitochondrial C1-tetrahydrofolate synthase; similar to YBR084W

Mitochondrial inner membrane ADP/ATP translocator; similar to YBR085W

Cortical ER protein involved in ER-plasma membrane tethering; similar to YBR086C

Subunit of heteropentameric Replication factor C (RF-C); similar to YBR087W

Proliferating cell nuclear antigen (PCNA); similar to YBR088C

Essential protein of the inner mitochondrial membrane; similar to YBR091C

Constitutively expressed acid phosphatase similar to Pho5p; similar to YBR092C

Repressible acid phosphatase; similar to YBR093C

tubulin tyrosine ligase associated with P-bodies; similar to YBR094W

Component of the histone deacetylase Rpd3L complex; similar to YBR095C

Serine/threonine protein kinase involved in vacuolar protein sorting; similar to YBR097W

Subunit of structure-specific Mms4p-Mus81p endonuclease; similar to YBR098W

Hsp70 (Ssa1p) nucleotide exchange factor; similar to YBR101C

Exocyst subunit with dual roles in exocytosis and spliceosome assembly; similar to YBR102C

WD40 repeat-containing subunit of Set3C histone deacetylase complex; similar to YBR103W

mitochondrial inner membrane transporter; similar to YBR104W

GID Complex regulatory subunit; similar to YBR105C

Probable membrane protein; similar to YBR106W

Outer kinetochore protein and component of the Ctf19 complex; similar to YBR107C

Protein that inhibits barbed-end actin filament elongation; similar to YBR108W

Nudix hydrolase family member with ADP-ribose pyrophosphatase activity; similar to YBR111C

General transcriptional co-repressor; similar to YBR112C

Nucleotide excision repair (NER) protein; similar to YBR114W

Alpha aminoadipate reductase; similar to YBR115C

Translational elongation factor EF-1 alpha; similar to YBR118W

Mitochondrial protein required for translation of the COB mRNA; similar to YBR120C

Cytoplasmic and mitochondrial glycyl-tRNA synthase; similar to YBR121C

Mitochondrial ribosomal protein of the large subunit; similar to YBR122C

Subunit of RNA polymerase III transcription initiation factor complex; similar to YBR123C

Cytoplasmic type 2C protein phosphatase (PP2C); similar to YBR125C

Synthase subunit of trehalose-6-P synthase/phosphatase complex; similar to YBR126C

Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase; similar to YBR127C

Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I; similar to YBR128C

Protein adaptor between Myo4p and the She2p-mRNA complex; similar to YBR130C

Subunit of a heterodimeric guanine nucleotide exchange factor (GEF); similar to YBR131W

Plasma membrane regulator of polyamine and carnitine transport; similar to YBR132C

Protein arginine N-methyltransferase; similar to YBR133C

Cyclin-dependent protein kinase regulatory subunit and adaptor; similar to YBR135W

DNA integrity checkpoint protein and PI kinase superfamily member; similar to YBR136W

Protein with a role in ER delivery of tail-anchored membrane proteins; similar to YBR137W

serine type carboxypeptidase; similar to YBR139W

GTPase-activating protein; similar to YBR140C

Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase; similar to YBR141C

Essential nucleolar protein; similar to YBR142W

Polypeptide release factor (eRF1) in translation termination; similar to YBR143C

Alcohol dehydrogenase isoenzyme V; similar to YBR145W

Mitochondrial ribosomal protein of the small subunit; similar to YBR146W

vacuolar membrane transporter for cationic amino acids; similar to YBR147W

Protein required for normal prospore membrane formation; similar to YBR148W

NADP+ dependent arabinose dehydrogenase; similar to YBR149W

mRNA splicing factor, component of U4/U6.U5 tri-snRNP; similar to YBR152W

Diaminohydroxyphoshoribosylaminopyrimidine deaminase; similar to YBR153W

RNA polymerase subunit ABC27; similar to YBR154C

TPR-containing co-chaperone; similar to YBR155W

Subunit of the conserved chromosomal passenger complex (CPC); similar to YBR156C

Protein required for daughter cell separation; similar to YBR158W

Microsomal beta-keto-reductase; similar to YBR159W

Cyclin-dependent kinase (CDK) catalytic subunit; similar to YBR160W

Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit; similar to YBR161W

Mitochondrial 5'-3' exonuclease and sliding exonuclease; similar to YBR163W

Soluble GTPase with a role in regulation of membrane traffic; similar to YBR164C

Ubiquitin-conjugating enzyme suppressor that regulates Cdc34p; similar to YBR165W

Prephenate dehydrogenase involved in tyrosine biosynthesis; similar to YBR166C

Subunit of both RNase MRP and nuclear RNase P; similar to YBR167C

Peroxisomal integral membrane protein; similar to YBR168W

Member of the heat shock protein 70 (HSP70) family; similar to YBR169C

Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase; similar to YBR170C

Non-essential subunit of Sec63 complex; similar to YBR171W

Chaperone required for correct maturation of the 20S proteasome; similar to YBR173C

Essential subunit of the COMPASS (Set1C) complex; similar to YBR175W

Ketopantoate hydroxymethyltransferase; similar to YBR176W

Acyl-coenzymeA:ethanol O-acyltransferase; similar to YBR177C

dityrosine transporter of the major facilitator superfamily; similar to YBR180W

Plasma membrane sulfite pump involved in sulfite metabolism; similar to YPL092W

Cytosolic and mitochondrial glutathione oxidoreductase; similar to YPL091W

Protein component of the small (40S) ribosomal subunit; similar to YPL090C

MADS-box transcription factor involved in osmotic stress response; similar to YBR182C

Membrane-associated mitochondrial ribosome receptor; similar to YBR185C

Hexameric ring ATPase that remodels chromosome axis protein Hop1p; similar to YBR186W

Member of the NineTeen Complex (NTC); similar to YBR188C

Protein component of the small (40S) ribosomal subunit; similar to YBR189W

Ribosomal 60S subunit protein L21A; similar to YBR191W

Mitochondrial pyrimidine nucleotide transporter; similar to YBR192W

Subunit of the RNA polymerase II mediator complex; similar to YBR193C

Protein proposed to be associated with the nuclear pore complex; similar to YBR194W

Subunit of chromatin assembly factor I (CAF-1); similar to YBR195C

Glycolytic enzyme phosphoglucose isomerase; similar to YBR196C

Subunit (90 kDa) of TFIID and SAGA complexes; similar to YBR198C

mannosyltransferase involved in protein glycosylation; similar to YBR199W

Protein containing SH3-domains; similar to YBR200W

ER membrane protein that promotes export of misfolded polypeptides; similar to YBR201W

Component of the Mcm2-7 hexameric helicase complex; similar to YBR202W

Protein required for antifungal drug ciclopirox olamine resistance; similar to YBR203W

alpha-1,2-mannosyltransferase; similar to YBR205W

high affinity iron transporter; similar to YBR207W

Protein involved in export of proteins from the endoplasmic reticulum; similar to YBR210W

Essential kinetochore protein associated with microtubules and SPBs; similar to YBR211C

RNA binding protein that negatively regulates growth rate; similar to YBR212W

Bifunctional dehydrogenase and ferrochelatase; similar to YBR213W

Protein involved in cell separation during budding; similar to YBR214W

Subunit of the HIR complex; similar to YBR215W

Protein involved in cellular response to oxidative stress; similar to YBR216C

Ubiquitin-like modifier involved in autophagy and the Cvt pathway; similar to YBR217W

Pyruvate carboxylase isoform; similar to YBR218C

E1 beta subunit of the pyruvate dehydrogenase (PDH) complex; similar to YBR221C

Oxalyl-CoA synthetase; similar to YBR222C

Tyrosyl-DNA phosphodiesterase I; similar to YBR223C

Mitochondrial matrix protein; similar to YBR227C

Endonuclease involved in DNA recombination and repair; similar to YBR228W

Glucosidase II catalytic subunit; similar to YBR229C

Mitochondrial outer membrane receptor for cytosolic ribosomes; similar to YBR230C

Component of the SWR1 complex; similar to YBR231C

Subunit of the ARP2/3 complex; similar to YBR234C

Vacuolar membrane cation-chloride cotransporter (CCC); similar to YBR235W

RNA helicase in the DEAD-box family; similar to YBR237W

Mitochondrial membrane protein; similar to YBR238C

Transcriptional regulator; similar to YBR239C

Transcriptional activator of thiamine biosynthetic genes; similar to YBR240C

transporter, member of the sugar porter family; similar to YBR241C

UDP-N-acetyl-glucosamine-1-P transferase; similar to YBR243C

Phospholipid hydroperoxide glutathione peroxidase; similar to YBR244W

ATPase subunit of imitation-switch (ISWI) class chromatin remodelers; similar to YBR245C

Methylesterase performing penultimate step of diphthamide biosynthesis; similar to YBR246W

Protein associated with U3 and U14 snoRNAs; similar to YBR247C

Imidazole glycerol phosphate synthase; similar to YBR248C

3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase; similar to YBR249C

Mitochondrial ribosomal protein of the small subunit; similar to YBR251W

deoxyuridine triphosphate diphosphatase (dUTPase); similar to YBR252W

Subunit of the RNA polymerase II mediator complex; similar to YBR253W

Core component of transport protein particle (TRAPP) complexes I-III; similar to YBR254C

Subunit of both RNase MRP and nuclear RNase P; similar to YBR257W

Subunit of the COMPASS (Set1C) complex; similar to YBR258C

GTPase-activating protein (RhoGAP) for Rho3p and Rho4p; similar to YBR260C

AdoMet-dependent proline methyltransferase; similar to YBR261C

Component of the MICOS complex; similar to YBR262C

Mitochondrial serine hydroxymethyltransferase; similar to YBR263W

Rab family GTP-binding protein; similar to YBR264C

3-ketosphinganine reductase; similar to YBR265W

Cytoplasmic pre-60S factor; similar to YBR267W

Mitochondrial ribosomal protein of the large subunit; similar to YBR268W

Protein required for assembly of succinate dehydrogenase; similar to YBR269C

Subunit of TORC2 membrane-associated complex; similar to YBR270C

S-adenosylmethionine-dependent methyltransferase; similar to YBR271W

Proteasome-interacting protein; similar to YBR272C

UBX (ubiquitin regulatory X) domain-containing protein; similar to YBR273C

Serine/threonine kinase and DNA damage checkpoint effector; similar to YBR274W

Protein that binds to the Rap1p C-terminus; similar to YBR275C

Third-largest subunit of DNA polymerase II (DNA polymerase epsilon); similar to YBR278W

Component of the Paf1p complex involved in transcription elongation; similar to YBR279W

F-Box protein involved in proteasome-dependent degradation of Aah1p; similar to YBR280C

Component of glutamine amidotransferase (GATase II); similar to YBR281C

Mitochondrial ribosomal protein of the large subunit; similar to YBR282W

Subunit of the Ssh1 translocon complex; similar to YBR283C

metallo-dependent hydrolase superfamily protein; similar to YBR284W

Vacuolar aminopeptidase Y; similar to YBR286W

Mu3-like subunit of the clathrin associated protein complex (AP-3); similar to YBR288C

Subunit of the SWI/SNF chromatin remodeling complex; similar to YBR289W

Heavy metal ion homeostasis protein; similar to YBR290W

Mitochondrial inner membrane citrate transporter; similar to YBR291C

Permease of basic amino acids in the vacuolar membrane; similar to YBR293W

High affinity sulfate permease of the SulP anion transporter family; similar to YBR294W

Cadmium transporting P-type ATPase; similar to YBR295W

Plasma membrane Na+/Pi cotransporter; similar to YBR296C

MAL-activator protein; similar to YBR297W

Transcriptional activator of the basic leucine zipper (bZIP) family; similar to YPR199C
Arsenate reductase required for arsenate resistance; similar to YPR200C
Plasma membrane metalloid/H+ antiporter; similar to YPR201W