Homo sapiens mitochondrion, complete genome.
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
Reanalysis and revision of the Cambridge reference sequence for human mitochondrial DNA
Sequence and organization of the human mitochondrial genome
Submitted (08-JUL-2009) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA
Submitted (24-AUG-2006) Mitomap.org, Center for Molecular and Mitochondrial Medicine and Genetics (MAMMAG) University of California, University of California, Irvine, Irvine, CA 92697-3940, USA
Submitted (18-APR-1997) Center for Molecular Medicine, Emory University School of Medicine, 1462 Clifton Road, Suite 420, Atlanta, GA 30322, USA
PROVISIONAL REFSEQ: This record has not yet been subject to final\nNCBI review. The reference sequence was derived from J01415.\nOn Jul 8, 2009 this sequence version replaced gi:115315570.\nThis sequence is a corrected version of the HUMMTCG reference\nsequence. The original Cambridge reference sequence (CRS) is\npreserved as GenBank J01415 gi:337188 [PMID:7219534]. Corrections\nhave been made and annotated per the re-sequencing of the original\nmaterial by Andrews et al [PMID:10508508].\n\nThis Revised Cambridge Reference Sequence (rCRS) has eighteen\nspecific corrections or confirmations of the original 1981 sequence\nof Anderson et al [PMID:7219534]. Seven nucleotides are confirmed\nas rare polymorphisms, maintained as: 263A, 311C-315C, 750A, 1438A,\n4769A, 8860A, and 15326A. Eleven nucleotides are error\ncorrections: 3107del, 3423T, 4985A, 9559C, 11335C, 13702C, 14199T,\n14272C, 14365C, 14368C, and 14766C. These 11 errors in the\noriginal Cambridge sequence were determined to be either outright\nsequencing errors (8 instances) or due to the presence of bovine\nDNA (2 instances) or HeLa DNA (1 instance) mixed in with the\noriginal human placental DNA [PMID:10508508]. HISTORICAL\nNUCLEOTIDE NUMBERS ARE MAINTAINED by indicating 3107del as 'N'.\nA summary table of the reanalysis data is available online at\nhttp://www.mitomap.org/MITOMAP/CambridgeReanalysis\n\nL-strand is shown.\nCOMPLETENESS: full length.
Official Symbol: MT-TF | Name: mitochondrially encoded tRNA phenylalanine | Provided by: HGNC:HGNC:7481
Official Symbol: MT-RNR1 | Name: mitochondrially encoded 12S RNA | Provided by: HGNC:HGNC:7470
Official Symbol: MT-TV | Name: mitochondrially encoded tRNA valine | Provided by: HGNC:HGNC:7500
Official Symbol: MT-RNR2 | Name: mitochondrially encoded 16S RNA | Provided by: HGNC:HGNC:7471
preserves historical genome annotation numbering
Official Symbol: MT-TL1 | Name: mitochondrially encoded tRNA leucine 1 (UUA/G) | Provided by: HGNC:HGNC:7490
Official Symbol: MT-ND1 | Name: mitochondrially encoded NADH dehydrogenase 1 | Provided by: HGNC:HGNC:7455
NADH dehydrogenase, subunit 1 (complex I); TAA stop codon is completed by the addition of 3' A residues to the mRNA
Official Symbol: MT-TI | Name: mitochondrially encoded tRNA isoleucine | Provided by: HGNC:HGNC:7488
Official Symbol: MT-TQ | Name: mitochondrially encoded tRNA glutamine | Provided by: HGNC:HGNC:7495
Official Symbol: MT-TM | Name: mitochondrially encoded tRNA methionine | Provided by: HGNC:HGNC:7492
Official Symbol: MT-ND2 | Name: mitochondrially encoded NADH dehydrogenase 2 | Provided by: HGNC:HGNC:7456
TAA stop codon is completed by the addition of 3' A residues to the mRNA
Official Symbol: MT-TW | Name: mitochondrially encoded tRNA tryptophan | Provided by: HGNC:HGNC:7501
Official Symbol: MT-TA | Name: mitochondrially encoded tRNA alanine | Provided by: HGNC:HGNC:7475
Official Symbol: MT-TN | Name: mitochondrially encoded tRNA asparagine | Provided by: HGNC:HGNC:7493
Official Symbol: MT-TC | Name: mitochondrially encoded tRNA cysteine | Provided by: HGNC:HGNC:7477
Official Symbol: MT-TY | Name: mitochondrially encoded tRNA tyrosine | Provided by: HGNC:HGNC:7502
Official Symbol: MT-CO1 | Name: mitochondrially encoded cytochrome c oxidase I | Provided by: HGNC:HGNC:7419
Official Symbol: MT-TS1 | Name: mitochondrially encoded tRNA serine 1 (UCN)
Official Symbol: MT-TD | Name: mitochondrially encoded tRNA aspartic acid | Provided by: HGNC:HGNC:7478
Official Symbol: MT-CO2 | Name: mitochondrially encoded cytochrome c oxidase II | Provided by: HGNC:HGNC:7421
Official Symbol: MT-TK | Name: mitochondrially encoded tRNA lysine | Provided by: HGNC:HGNC:7489
Official Symbol: MT-ATP8 | Name: mitochondrially encoded ATP synthase 8 | Provided by: HGNC:HGNC:7415
Official Symbol: MT-ATP6 | Name: mitochondrially encoded ATP synthase 6 | Provided by: HGNC:HGNC:7414
Official Symbol: MT-CO3 | Name: mitochondrially encoded cytochrome c oxidase III | Provided by: HGNC:HGNC:7422
cytochrome c oxidase III; TAA stop codon is completed by the addition of 3' A residues to the mRNA
Official Symbol: MT-TG | Name: mitochondrially encoded tRNA glycine | Provided by: HGNC:HGNC:7486
Official Symbol: MT-ND3 | Name: mitochondrially encoded NADH dehydrogenase 3 | Provided by: HGNC:HGNC:7458
NADH dehydrogenase, subunit 3 (complex I); TAA stop codon is completed by the addition of 3' A residues to the mRNA
Official Symbol: MT-TR | Name: mitochondrially encoded tRNA arginine | Provided by: HGNC:HGNC:7496
Official Symbol: MT-ND4L | Name: mitochondrially encoded NADH 4L dehydrogenase | Provided by: HGNC:HGNC:7460
NADH dehydrogenase, subunit 4L (complex I)
Official Symbol: MT-ND4 | Name: mitochondrially encoded NADH dehydrogenase 4 | Provided by: HGNC:HGNC:7459
NADH dehydrogenase, subunit 4 (complex I); TAA stop codon is completed by the addition of 3' A residues to the mRNA
Official Symbol: MT-TH | Name: mitochondrially encoded tRNA histidine | Provided by: HGNC:HGNC:7487
Official Symbol: MT-TS2 | Name: mitochondrially encoded tRNA serine 2 (AGU/C) | Provided by: HGNC:HGNC:7498
Official Symbol: MT-TL2 | Name: mitochondrially encoded tRNA leucine 2 (CUN) | Provided by: HGNC:HGNC:7491
Official Symbol: MT-ND5 | Name: mitochondrially encoded NADH dehydrogenase 5 | Provided by: HGNC:HGNC:7461
NADH dehydrogenase, subunit 5 (complex I)
Official Symbol: MT-ND6 | Name: mitochondrially encoded NADH dehydrogenase 6 | Provided by: HGNC:HGNC:7462
NADH dehydrogenase, subunit 6 (complex I)
Official Symbol: MT-TE | Name: mitochondrially encoded tRNA glutamic acid | Provided by: HGNC:HGNC:7479
Official Symbol: MT-CYB | Name: mitochondrially encoded cytochrome b | Provided by: HGNC:HGNC:7427
Official Symbol: MT-TT | Name: mitochondrially encoded tRNA threonine | Provided by: HGNC:HGNC:7499
Official Symbol: MT-TP | Name: mitochondrially encoded tRNA proline | Provided by: HGNC:HGNC:7494