CSSO: Clinical Signs and Symptoms Ontology
type: Ontology
description: An ontology for describing clinical signs and symptoms.
creator: Nozomi YAMAMOTO
version info: Version 0.2
imports: oboInOwl

has_obo_format_version
type: AnnotationProperty

has_exact_synonym
type: AnnotationProperty

definition
type: AnnotationProperty

has_related_synonym
type: AnnotationProperty

database_cross_reference
type: AnnotationProperty

has_alternative_id
type: AnnotationProperty

has_obo_namespace
type: AnnotationProperty

alternative label
type: AnnotationProperty
definition: Section 5. Lexical Labels

Abdomen and digestive system symptom
type: Class
subclass of: Thing

Abdominal symptom
type: Class
subclass of: Abdomen and digestive system symptom

Abnormal behavior
type: Class
subclass of: Cognition, perception, emotional state and behavior system symptom
definition: Behavior that deviates from what is commonly accepted by a group or society.
alternative label: Strange behavior

Abnormal blood pressure
type: Class
subclass of: Circulatory system symptom

Abnormal breathing
type: Class
subclass of: Respiratory system symptom
alternative label: Abnormalities of breathing
alternative label: Breathing abnormal
alternative label: Breathing problem
alternative label: Respiration abnormal

Abnormal heart beat
type: Class
subclass of: Heart symptom
alternative label: Abnormal heart beats
alternative label: Abnormalities of heart beat

Abortion
type: Class
subclass of: Reproductive system symptom
definition: The spontaneous or induced termination of pregnancy before the fetus has developed to the stage of viability.

Alteration of consciousness
type: Class
subclass of: Cognition, perception, emotional state and behavior system symptom
alternative label: Altered consciousness
alternative label: Disturbance of consciousness

Bloodstream symptom
type: Class
subclass of: Hematic system symptom

Blood vessel infection
type: Class
subclass of: Bloodstream symptom

Change in skin color
type: Class
subclass of: Skin symptom

Chest symptom
type: Class
subclass of: Respiratory system symptom

Circulatory system symptom
type: Class
subclass of: Thing

Cognition, perception, emotional state and behavior system symptom
type: Class
subclass of: Thing

Discharge
type: Class
subclass of: General symptom

Ear symptom
type: Class
subclass of: Head symptom

Eye symptom
type: Class
subclass of: Head symptom

Eyelid symptom
type: Class
subclass of: Eye symptom

Feces symptom
type: Class
subclass of: Abdomen and digestive system symptom

Food and fluid intake system symptom
type: Class
subclass of: Thing

Gastrointestinal symptom
type: Class
subclass of: Abdominal symptom

General symptom
type: Class
subclass of: Thing
definition: A symptom that affects the entire body rather than a specific organ or location.

Head and neck symptom
type: Class
subclass of: Thing

Head symptom
type: Class
subclass of: Head and neck symptom

Heart symptom
type: Class
subclass of: Circulatory system symptom

Hematic system symptom
type: Class
subclass of: Circulatory system symptom

Immune system symptom
type: Class
subclass of: Thing

Infant symptom
type: Class
subclass of: Food and fluid intake system symptom

Joint symptom
type: Class
subclass of: Musculoskeletal system symptom

Lesion
type: Class
subclass of: General symptom
definition: Any visible, local abnormality of the tissues of the skin, such as a wound, sore, rash, or boil.

Liver symptom
type: Class
subclass of: Abdomen and digestive system symptom

Lymphatic system symptom
type: Class
subclass of: Immune system symptom

Bleeding mouth
type: Class
subclass of: Mouth symptom
alternative label: Hemorrhage from mouth
alternative label: Oral hemorrhage

Mouth symptom
type: Class
subclass of: Head symptom

Muscle symptom
type: Class
subclass of: Musculoskeletal system symptom

Musculoskeletal system symptom
type: Class
subclass of: Thing

Neck symptom
type: Class
subclass of: Head and neck symptom

Nervous system symptom
type: Class
subclass of: Thing

Nose symptom
type: Class
subclass of: Head symptom

Reproductive system symptom
type: Class
subclass of: Thing

Respiratory system symptom
type: Class
subclass of: Thing
alternative label: Raspiratory symptom

Sensory disturbance
type: Class
subclass of: Cognition, perception, emotional state and behavior system symptom
alternative label: Sensory disorder

Skin symptom
type: Class
subclass of: Thing

Sleep disturbance
type: Class
subclass of: Nervous system symptom
definition: Any condition that interferes with sleep.
alternative label: Dyssomnia
alternative label: Sleep problem

Speech and voice system symptom
type: Class
subclass of: Skin symptom

Spleen symptom
type: Class
subclass of: Immune system symptom

Stiffness
type: Class
subclass of: General symptom

Thoracic symptom
type: Class
subclass of: Thing
alternative label: Breast symptom

Throat symptom
type: Class
subclass of: Respiratory system symptom

Urinary system symptom
type: Class
subclass of: Thing

Vascular symptom
type: Class
subclass of: Hematic system symptom

Visual symptom
type: Class
subclass of: Eye symptom
alternative label: Vision disorder

Weakness
type: Class
subclass of: General symptom
definition: A condition of being feeble, fragile, frail, or decrepit or lacking physical strength, energy, or vigor.
alternative label: Debility
alternative label: Lassitude

Abdominal cramp
type: Class
subclass of: Abdominal symptom
alternative label: Abdominal cramps
alternative label: Stomach cramp
alternative label: Stomach cramps

Abdominal discomfort
type: Class
subclass of: Abdominal symptom
alternative label: Discomfort in abdomen

Abdominal pain
type: Class
subclass of: Abdominal symptom
alternative label: Abdominal pains
definition: Acute or chronic, localized or diffuse pain in the abdominal cavity.

Abdominal tenderness
type: Class
subclass of: Abdominal symptom

Abscess
type: Class
subclass of: Lesion
definition: A localized collection of pus in part of the body, formed by tissue disintegration and surrounded by an inflamed area.
alternative label: Abscesses

Altered mental status
type: Class
subclass of: Cognition, perception, emotional state and behavior system symptom
alternative label: Change in mental status
alternative label: Mental status change

Anemia
type: Class
subclass of: Hematic system symptom
definition: A condition in which there is an abnormally low number of red blood cells in the bloodstream.
alternative label: Anaemia

Anorexia
type: Class
subclass of: Food and fluid intake system symptom
alternative label: Lack of appetite
definition: Lack or loss of appetite for food.
alternative label: Loss of appetite
alternative label: Poor appetite

Anus pain
type: Class
subclass of: Gastrointestinal symptom
alternative label: Anal pain

Apnea
type: Class
subclass of: Abnormal breathing
alternative label: Apnoea
alternative label: Not breathing
definition: The temporary absence of breathing.

Arthritis
type: Class
subclass of: Musculoskeletal system symptom
definition: An inflammation of joints.
alternative label: Inflammatory disorder of joint

Ascites
type: Class
subclass of: Abdominal symptom
alternative label: Abdominal dropsy
definition: An abnormal accumulation of fluid in the abdomen.
alternative label: Fluid in the abdomen
alternative label: Hydroperitoneum
alternative label: Hydroperitonia

Asthenia
type: Class
subclass of: General symptom
definition: Physical weakness and loss of strength.

Backache
type: Class
subclass of: Musculoskeletal system symptom
definition: A pain in the back.
alternative label: Back ache
alternative label: Back pain
alternative label: Dorsalgia
alternative label: Pain in back

Bacteremia
type: Class
subclass of: Blood vessel infection
definition: An invasion of the bloodstream by bacteria.
alternative label: Bacteraemia

Bladder irritability
type: Class
subclass of: Urinary system symptom
definition: A condition of the bladder marked by increased frequency of contraction with associated desire to urinate.
alternative label: Bladder instability
alternative label: Irritable bladder
alternative label: Unstable bladder

Bleeding
type: Class
subclass of: General symptom
definition: Escape of blood from an injured vessel.
alternative label: Hemorrhage

Blepharitis
type: Class
subclass of: Eyelid symptom
alternative label: Eyelid inflammation
alternative label: Inflammation of eyelid
alternative label: Inflammation of lid margin
definition: Inflammation of the eyelids.

Blindness
type: Class
subclass of: Visual symptom
definition: The absence of sight.

Blister
type: Class
subclass of: Skin symptom
definition: A vesicle or bulla of the skin, containing watery matter or serum.
alternative label: Bleb
alternative label: Blistering
alternative label: Blisters
alternative label: Bulla

Blood in urine
type: Class
subclass of: Urinary system symptom
definition: Abnormal presence of blood in the urine.
alternative label: Hematuria

Bloody diarrhea
type: Class
subclass of: Diarrhea
alternative label: Bloody diarrhoea
alternative label: Haemorrhagic diarrhoea
alternative label: Hemorrhagic diarrhea

Bloody stool
type: Class
subclass of: Feces symptom
alternative label: Blood in feces
alternative label: Blood in stool
definition: Blood in the feces.
alternative label: Haematochezia
alternative label: Hematochezia

Furuncle
type: Class
subclass of: Skin symptom
definition: A tender, swollen area that forms around a hair follicle.
alternative label: Boil
alternative label: Boils
alternative label: Furuncles
alternative label: Furunculosis

Bone pain
type: Class
subclass of: Musculoskeletal system symptom
definition: A pain in a bone.
alternative label: Ostealgia
alternative label: Osteodynia

Bradycardia
type: Class
subclass of: Abnormal heart beat
definition: A slow heart rate, usually under 60 beats per minute in adults.
alternative label: Decreased heart rate
alternative label: Heart rate slow
alternative label: Slow heart beat

Brain lesion
type: Class
subclass of: Nervous system symptom
alternative label: Lesion of brain

Induration of breast
type: Class
subclass of: Thoracic symptom
alternative label: Breast hardness
alternative label: Mastoscirrhus

Breast pain
type: Class
subclass of: Thoracic symptom
alternative label: Mastalgia
alternative label: Mastodynia
alternative label: Pain of breast
alternative label: Painful breasts

Breast tenderness
type: Class
subclass of: Thoracic symptom
alternative label: Tender breasts
alternative label: Tenderness of breast

Burning on urination
type: Class
subclass of: Dysuria
alternative label: Burning pain on urination
alternative label: Scalding pain on urination

Caseation
type: Class
subclass of: Necrosis
alternative label: Caseous necrosis
definition: Necrosis in which tissue is changed into a dry mass resembling cheese.

Cellulitis
type: Class
subclass of: Musculoskeletal system symptom
definition: A spreading inflammation of subcutaneous or connective tissue.

Chest pain
type: Class
subclass of: Chest symptom

Chills
type: Class
subclass of: General symptom
definition: A sensation of cold, with convulsive shaking of the body.
alternative label: Chill
alternative label: Rigor

Chronic cough
type: Class
subclass of: Cough
definition: Chronic cough is a cough characterized by an explosive expulsion of air from the lungs acting as a protective mechanism to clear the air passages or as a symptom of pulmonary disturbance marked by long duration, by frequent recurrence over a long time, and often by slowly progressing seriousness.

Coma
type: Class
subclass of: Alteration of consciousness
definition: A state of profound unconsciousness, characterized by the absence of spontaneous eye openings, response to painful stimuli, and vocalization.
alternative label: Comatose
alternative label: Exanimation

Confusion
type: Class
subclass of: Altered mental status
alternative label: Bewilderment
alternative label: Disorientation
definition: Impaired orientation with respect to time, place, or person.

Nasal congestion
type: Class
subclass of: Respiratory system symptom
alternative label: Congested nose
definition: Difficulty in nasal breathing.
alternative label: Nasal stuffiness
alternative label: Stuffed-up nose

Constipation
type: Class
subclass of: Feces symptom
definition: An acute or chronic condition in which bowel movements occur less often than usual or consist of hard, dry stools that are painful or difficult to pass.
alternative label: Costiveness
alternative label: Difficult passing motion
alternative label: Difficulty defecating

Cough
type: Class
subclass of: Respiratory system symptom
definition: A forceful release of air from the lungs that can be heard.

Deafness
type: Class
subclass of: Ear symptom
alternative label: Difficulty hearing
alternative label: Hearing impairment
alternative label: Hearing loss
definition: The lack or loss of the ability to hear.

Hypochlorhydria
type: Class
subclass of: Gastrointestinal symptom
definition: Decreased gastric acid secretion.
alternative label: Decreased gastric acidity
alternative label: Hypoacidity

Deep abscess
type: Class
subclass of: Abscess
alternative label: Deep abscesses

Deformation
type: Class
subclass of: General symptom
definition: An alteration in shape or structure.
alternative label: Deformity

Delirium
type: Class
subclass of: Altered mental status
definition: A state of mental confusion that develops quickly and usually fluctuates in intensity.

Desquamation
type: Class
subclass of: Skin symptom
alternative label: Changes in skin texture
alternative label: Desquamation of skin
alternative label: Peeling of skin
alternative label: Scaling of skin
definition: Shedding of the cells lining the insides of the air sacs.

Diaphoresis
type: Class
subclass of: General symptom
alternative label: Hidropoiesis
alternative label: Perspiration
alternative label: Sweating
definition: The secretion of sweat, especially the profuse secretion associated with an elevated body temperature, physical exertion, exposure to heat, and mental or emotional stress.

Diarrhea
type: Class
subclass of: Feces symptom
alternative label: Diarrhoea
definition: Excessive and frequent evacuation of watery feces.
alternative label: Loose bowel motions
alternative label: Loose bowel movement

Discharge from penis
type: Class
subclass of: Reproductive system symptom
alternative label: Penile discharge

Dizziness
type: Class
subclass of: Cognition, perception, emotional state and behavior system symptom
definition: A sensation of faintness and whirling or an inability to maintain normal balance in a standing or seated position.

Drowsiness
type: Class
subclass of: Sleep disturbance
definition: A state of impaired awareness associated with a desire or inclination to sleep.
alternative label: Sleepiness
alternative label: Somnolence

Dry cough
type: Class
subclass of: Cough
definition: A cough that does not produce sputum.
alternative label: Non-productive cough
alternative label: Unproductive cough

Dyspareunia
type: Class
subclass of: Reproductive system symptom
alternative label: Coitalgia
definition: Difficult or painful sexual intercourse.
alternative label: Pain on intercourse

Dysphagia
type: Class
subclass of: Throat symptom
alternative label: Difficulty in swallowing
definition: Difficulty in swallowing or inability to swallow.
alternative label: Swallowing difficult

Dyspnea
type: Class
subclass of: Abnormal breathing
definition: A difficulty in breathing or shortness of breath.
alternative label: Breathless
alternative label: Breathlessness
alternative label: Difficulity breathing
alternative label: Dyspnoea
alternative label: Shortness of breath

Dysuria
type: Class
subclass of: Urinary system symptom
definition: Difficult or painful urination.
alternative label: Pain emptying bladder
alternative label: Pain on micturition
alternative label: Pain on voiding
alternative label: Urination painful

Earache
type: Class
subclass of: Ear symptom
alternative label: Ear pain
alternative label: Otalgia
definition: Pain in the ear.

Edema
type: Class
subclass of: Skin symptom
definition: A condition of abnormally large fluid volume in the circulatory system or in tissues between the body's cells.
alternative label: Dropsy
alternative label: Oedema

Erythema
type: Class
subclass of: Change in skin color
alternative label: Hyperemia
alternative label: Red skin
definition: Redness of the skin.

Eschar
type: Class
subclass of: Skin symptom
definition: A hard crust or scab.

Eye discharge
type: Class
subclass of: Eye symptom
alternative label: Discharge from eye
alternative label: Sticky eye

Eye pain
type: Class
subclass of: Eye symptom
alternative label: Ocular pain
alternative label: Pain in eye

Eyelid pain
type: Class
subclass of: Eyelid symptom

Facial swelling
type: Class
subclass of: Head symptom
alternative label: Swollen face

Fatigue
type: Class
subclass of: General symptom
alternative label: Lassitude
definition: Physical and/or mental exhaustion that can be triggered by stress, medication, overwork, or mental and physical illness or disease.
alternative label: Tiredness
alternative label: Weariness

Fatty stool
type: Class
subclass of: Feces symptom
definition: Feces containing an abnormally large amount of fat.
alternative label: Steatorrhea
alternative label: Steatorrhoea

Fever
type: Class
subclass of: General symptom
definition: An abnormally high body temperature.
alternative label: Febrile
alternative label: Pyrexia

Gallbladder pain
type: Class
subclass of: Abdominal symptom

Granuloma
type: Class
subclass of: Immune system symptom
definition: A collection of inflammatory cells forming a microscopic lesion.

Bleeding gums
type: Class
subclass of: Bleeding mouth
alternative label: Gingival bleeding
alternative label: Gingival haemorrhage
alternative label: Gingival hemorrhage
alternative label: Gum bleeding
definition: Gum bleeding is a mouth symptom characterized by a copious discharge of blood from the blood vessels of the mucosal tissue that lies over the alveolar bone.

Gum pain
type: Class
subclass of: Mouth symptom
alternative label: Gingival pain
alternative label: Gingivalgia
alternative label: Painful gums
alternative label: Sore gums

Swollen gums
type: Class
subclass of: Mouth symptom
alternative label: Gingival swelling
alternative label: Gum swelling
alternative label: Swelling of the gum

Headache
type: Class
subclass of: Head symptom
definition: A pain in the head.
alternative label: Cephalalgia
alternative label: Cephalgia
alternative label: Head pain

Hemolytic anemia
type: Class
subclass of: Anemia
definition: A disorder in which the red blood cells are destroyed prematurely.
alternative label: Hemolytic anaemia

Hepatomegaly
type: Class
subclass of: Liver symptom
alternative label: Enlarged liver
definition: Enlargement of the liver.
alternative label: Large liver

Hepatosplenomegaly
type: Class
subclass of: Liver symptom
subclass of: Spleen symptom
definition: Enlargement of the liver and the spleen.

High fever
type: Class
subclass of: Fever
definition: A fever with an elevated temperature.
alternative label: High-grade fever

Hyperhidrosis
type: Class
subclass of: Diaphoresis
definition: A disorder marked by excessive sweating.

Hypertension
type: Class
subclass of: Abnormal blood pressure
definition: Abnormally high blood pressure.
alternative label: Elevated blood pressure
alternative label: High blood pressure

Hypotension
type: Class
subclass of: Abnormal blood pressure
definition: Abnormally low blood pressure.
alternative label: Low blood pressure

Impotence
type: Class
subclass of: Reproductive system symptom
alternative label: Erectile dysfunction
alternative label: Failure of erection
definition: The inability to achieve or maintain an erection long enough to engage in sexual intercourse.

Inflammation
type: Class
subclass of: General symptom
definition: A localized protective reaction characterized by increased blood supply and activation of defense mechanisms. It produces redness, swelling, heat, and pain.
alternative label: Inflammations

Irritability
type: Class
subclass of: Cognition, perception, emotional state and behavior system symptom
definition: A condition of abnormal excitability or sensitivity.
alternative label: Feeling irritable
alternative label: Inconsolability
alternative label: Irritable mood

Itching
type: Class
subclass of: Skin symptom
definition: An intense, distracting irritation or tickling sensation that may be felt all over the skin's surface, or confined to just one area.
alternative label: Itch
alternative label: Itchy
alternative label: Pruritus

Jaundice
type: Class
subclass of: Skin symptom
definition: A yellow discoloration of the skin, mucous membranes, and sclerae of the eyes caused by greater than normal amounts of bilirubin in the blood.
alternative label: Icteric
alternative label: Icterus
alternative label: Jaundiced

Joint pain
type: Class
subclass of: Joint symptom
alternative label: Aching joints
alternative label: Arthralgia
alternative label: Articular pain
definition: Pain in a joint.

Joint stiffness
type: Class
subclass of: Joint symptom
definition: Pain on moving a joint, loss of range of motion, or reduced range of motion.
alternative label: Stiff joint

Joint swelling
type: Class
subclass of: Joint symptom
alternative label: Swollen joint

Joint tenderness
type: Class
subclass of: Joint symptom
alternative label: Joint tender

Joint warm
type: Class
subclass of: Joint symptom

Large tonsil
type: Class
subclass of: Immune system symptom
alternative label: Enlarged tonsil
alternative label: Swollen tonsil

Leg cramp
type: Class
subclass of: Muscle cramp
alternative label: Leg cramps
alternative label: Muscle cramps in leg

Leg pain
type: Class
subclass of: Musculoskeletal system symptom
alternative label: Pain in lower limb.

Leukocytosis
type: Class
subclass of: Hematic system symptom
definition: A condition characterized by an elevated number of white cells in the blood.
alternative label: Leucocytosis
alternative label: White blood cell count increased

Leukopenia
type: Class
subclass of: Hematic system symptom
definition: A condition in which the number of leukocytes circulating in the blood is abnormally low.
alternative label: Decreased blood leucocyte number
alternative label: Leucopenia
alternative label: White blood cell decreased

Photophobia
type: Class
subclass of: Eye symptom
definition: An abnormal sensitivity to light.
alternative label: Light sensitivities
alternative label: Light sensitivity
alternative label: Sensitivity to light

Liver pain
type: Class
subclass of: Liver symptom
alternative label: Hepatic pain

Loss of teeth
type: Class
subclass of: Mouth symptom
alternative label: Tooth loss

Low back pain
type: Class
subclass of: Backache
alternative label: Low backache
alternative label: Lumbago
definition: Pain in the lumbar region.

Low grade fever
type: Class
subclass of: Fever
alternative label: Low fever
alternative label: Low-grade fever
definition: Low-grade fever is a fever that does not exceed 38.5 degree centrigrade.
alternative label: Mild fever
alternative label: Mild pyrexia
alternative label: Slight fever

Lymphadenitis
type: Class
subclass of: Lymphatic system symptom
alternative label: Adenitis
definition: An inflammation of a lymph node.
alternative label: Inflammation of lymph node

Lymphadenopathy
type: Class
subclass of: Lymphatic system symptom
definition: Any disorder characterized by a localized or generalized enlargement of the lymph nodes or lymph vessels.
alternative label: Enlarged glands
alternative label: Enlargement of lymph nodes
alternative label: Swelling of lymph node
alternative label: Swollen lymph glands
alternative label: Swollen lymph nodes

Lymphangitis
type: Class
subclass of: Lymphatic system symptom
alternative label: Inflammation of lymphatics
definition: Inflammation of the lymphatic vessels.

Lymphocytosis
type: Class
subclass of: Lymphatic system symptom
definition: A condition in which the number of lymphocytes increases above normal levels.
alternative label: Increased blood lymphocyte number

Maculopapular rash
type: Class
subclass of: Rash
definition: A rash characterized by raised, spotted lesions.

Malaise
type: Class
subclass of: General symptom
definition: A general sense of depression or unease.
alternative label: Feels unwell
alternative label: Not feeling well

Malodor
type: Class
subclass of: General symptom
definition: A distinctive odor that is offensively unpleasant.
alternative label: Bad odor
alternative label: Foul odor
alternative label: Stench

Meningismus
type: Class
subclass of: Nervous system symptom
definition: An abnormal condition characterized by irritation of the brain and spinal cord.
alternative label: Meningeal irritation
alternative label: Meningism

Multiple organ failure
type: Class
subclass of: General symptom
definition: Failure of two or more organ systems in a critically ill patient.
alternative label: Multi-organ failure
alternative label: Multiple system failure

Muscle cramp
type: Class
subclass of: Muscle symptom
definition: A sudden intermittent pain in almost any part of the body.
alternative label: Cramp
alternative label: Muscle cramps

Muscle tone
type: Class
subclass of: Muscle symptom
alternative label: Muscle tightness
alternative label: Muscle tonus
definition: The slight, continuous contraction of a muscle.

Muscle weakness
type: Class
subclass of: Muscle symptom
alternative label: Decreased muscle strength
alternative label: Incomplete paralysis

Myalgia
type: Class
subclass of: Muscle symptom
alternative label: Muscle ache
alternative label: Muscle pain
definition: Muscular pain or tenderness.

Nausea
type: Class
subclass of: Abdomen and digestive system symptom
definition: An unpleasant sensation characterized by gastrointestinal distress and an urge to vomit.
alternative label: Nauseated

Neck pain
type: Class
subclass of: Neck symptom
definition: An unpleasant sensation localized in the neck.
alternative label: Cervical pain
alternative label: Cervicalgia
alternative label: Cervicodynia
alternative label: Neck ache

Neck swelling
type: Class
subclass of: Neck symptom

Necrosis
type: Class
subclass of: General symptom
alternative label: Cellular necrosis
definition: The death of cells, a portion of tissue, or a portion of an organ due to permanent damage of some sort, such as loss of blood supply, bacterial toxins, or physical or chemical agents.
alternative label: Tissue devitalization

Neoplasm
type: Class
subclass of: General symptom
definition: An abnormal formation of tissue.
alternative label: Neoplasms
alternative label: Tumor
alternative label: Tumour

Neurological deficit
type: Class
subclass of: Nervous system symptom
definition: Any defect or absence of function of a peripheral nerve or a system.

Night sweats
type: Class
subclass of: Diaphoresis
alternative label: Night sweating
definition: The occurrence of excessive sweating during sleep.

Nodule
type: Class
subclass of: General symptom
definition: A small node that may form on a tendon and make it difficult to slide smoothly through its sheath.

Pain
type: Class
subclass of: General symptom
alternative label: Aches
definition: An unpleasant sensation caused by stimulation of specialized nerve endings.

Papule
type: Class
subclass of: Rash
definition: A small hard elevation of the skin.
alternative label: Papula
alternative label: Papulae
alternative label: Papular lesion

Papulovesicular rash
type: Class
subclass of: Rash

Paralysis
type: Class
subclass of: Nervous system symptom
definition: Complete loss of strength in an affected limb or muscle group.
alternative label: Muscular paralysis
alternative label: Palsy

Paresthesia
type: Class
subclass of: Skin symptom
definition: An altered sensation often described as burning, tingling, or pin pricks.
alternative label: Paraesthesia

Petechiae
type: Class
subclass of: Skin symptom
alternative label: Petachial eruption
alternative label: Petechia
alternative label: Petechial rash
definition: Tiny purple or red spots on the skin resulting from hemorrhages within the dermal or submucosal layers.

Phlegm
type: Class
subclass of: Respiratory system symptom
definition: Thick mucus secreted by the tissues lining the airways of the lungs.
alternative label: Upper respiratory tract mucus

Pigmentation
type: Class
subclass of: Change in skin color
alternative label: Skin pigmentation
definition: The coloration or discoloration of a part by a pigment.

Pleural effusion
type: Class
subclass of: Skin symptom
definition: An exudation of fluid from the blood or lymph into a pleural cavity.

Pleuritic chest pain
type: Class
subclass of: Chest pain
definition: Acute inflammation of the intercostal muscles and the muscular attachment of the diaphragm to the chest wall.
alternative label: Pleuralgia
alternative label: Pleuritic pain

Pneumonia
type: Class
subclass of: Chest symptom
definition: An infection of the lung that can be caused by nearly any class of organism known to cause human infections.

Poor feeding
type: Class
subclass of: Infant symptom
alternative label: Feeding poor

Prostration
type: Class
subclass of: General symptom
alternative label: Extreme exhaustion
definition: Extreme exhaustion or lack of energy or power.

Proteinuria
type: Class
subclass of: Urinary system symptom
alternative label: Albuminuria
definition: The presence of protein in the urine exceeding normal levels.

Pyuria
type: Class
subclass of: Urinary system symptom
alternative label: Pus cells in urine
definition: The presence of an excessive number of white blood cells in the urine.

Raised intracranial pressure
type: Class
subclass of: Head symptom
definition: Elevation of the pressure in the cranium.
alternative label: Intracranial hypertension

Rash
type: Class
subclass of: Skin symptom
definition: A skin eruption.
alternative label: Eruption
alternative label: Exanthema
alternative label: Skin eruption
alternative label: Skin rash

Rectal pain
type: Class
subclass of: Gastrointestinal symptom
alternative label: Pain in rectum
alternative label: Proctalgia
alternative label: Rectalgia

Rectorrhagia
type: Class
subclass of: Gastrointestinal symptom
alternative label: Hemorrhage of rectum
alternative label: Proctorrhagia
alternative label: Rectal bleeding

Regional adenopathy
type: Class
subclass of: Lymphadenopathy
alternative label: Localized enlarged lymph nodes

Relapsing fever
type: Class
subclass of: Fever
definition: A fever where the body temperature periodically rises and falls.
alternative label: Recurrent fever

Respiratory failure
type: Class
subclass of: Respiratory system symptom
definition: Any condition that affects breathing function or the lungs themselves and can result in failure of the lungs to function properly.
alternative label: Respiratory insufficiency

Rose spots
type: Class
subclass of: Rash
alternative label: Roseola
alternative label: Rosy spots
definition: Small slightly raised reddish pimples that are a distinguishing feature of typhoid or paratyphoid infection.
alternative label: Typhoid exanthem

Runny nose
type: Class
subclass of: Nose symptom
alternative label: Discharge from nose
alternative label: Nasal discharge
alternative label: Rhinorrhea
alternative label: Rhinorrhoea
definition: The free discharge of a thin watery nasal fluid.

Seizure
type: Class
subclass of: Nervous system symptom
definition: A sudden attack, spasm, or convulsion.
alternative label: Convulsion
alternative label: Seizures

Sensory loss
type: Class
subclass of: Sensory disturbance
alternative label: Absence of sensation
alternative label: Anesthesia
alternative label: Loss of sensation
definition: Total or partial loss of sensation.

Septicemia
type: Class
subclass of: Hematic system symptom
definition: A disease in which bacteria invades the bloodstream and circulates throughout the body.
alternative label: Sepsis

Severe headache
type: Class
subclass of: Headache

Severe pain
type: Class
subclass of: Pain
alternative label: Intense pain

Shock
type: Class
subclass of: General symptom
definition: A medical emergency in which the organs and tissues of the body are not receiving an adequate flow of blood.
alternative label: Circulatory collapse
alternative label: Circulatory failure

Skin irritation
type: Class
subclass of: Skin symptom
alternative label: Irritation of skin
definition: Reaction to a particular irritant that results in inflammation of the skin and itchiness.

Skin lesion
type: Class
subclass of: Skin symptom
definition: A superficial growth or patch of the skin that does not resemble the area surrounding it.

Skin ulcer
type: Class
subclass of: Skin lesion
definition: A skin lesion characterized as a break in skin with loss of surface tissue, disintegration and necrosis of epithelial tissue, and often pus.
alternative label: Cutaneous ulcer
alternative label: Ulcer of skin

Splenomegaly
type: Class
subclass of: Spleen symptom
alternative label: Enlarged spleen
alternative label: Enlargement of spleen
definition: Enlargement of the spleen.
alternative label: Large spleen

Spontaneous abortion
type: Class
subclass of: Abortion
definition: A naturally occurring termination of a pregnancy.
alternative label: Miscarriage

Sputum
type: Class
subclass of: Respiratory system symptom
alternative label: Expectoration
alternative label: Sputum production
definition: The substance that is brought up from the lungs and airway when a person coughs or spits. It is a mixture of saliva and mucus, and may contains may blood or pus.

Stiff jaw
type: Class
subclass of: Head symptom
alternative label: Jaw stiffness

Stiff neck
type: Class
subclass of: Neck symptom
alternative label: Crick in neck
alternative label: Neck stiffness

Stillbirth
type: Class
subclass of: Reproductive system symptom
definition: The death of a fetus at any time after the twentieth week of pregnancy.

Stupor
type: Class
subclass of: Alteration of consciousness
definition: A state of unresponsiveness in which a person seems unaware of the surroundings.

Swelling
type: Class
subclass of: General symptom
definition: Transient abnormal enlargement of a body part or area.

Swelling of breast
type: Class
subclass of: Thoracic symptom
alternative label: Breast swelling

Swelling of skin
type: Class
subclass of: Skin symptom

Swelling of eyelid
type: Class
subclass of: Eyelid symptom

Swallowing painful
type: Class
subclass of: Throat symptom
definition: A dysphagia in which swallowing causes pain.
alternative label: Odynophagia
alternative label: Pain on swallowing
alternative label: Painful swallowing

Tachycardia
type: Class
subclass of: Abnormal heart beat
definition: Abnormally rapid heart rate, especially above 100 beats per minute in adults.
alternative label: Heart rate fast
alternative label: Increased heart rate
alternative label: Rapid hear beat

Tachypnea
type: Class
subclass of: Abnormal breathing
definition: An abnormally rapid rate of breathing
alternative label: Increased respiratory rate
alternative label: Rapid breathing
alternative label: Rapid respiration
alternative label: Tachypnoea

Teary eye
type: Class
subclass of: Eye symptom
alternative label: Runny eye

Tender lymph node
type: Class
subclass of: Lymphatic system symptom
alternative label: Lymph node tenderness
alternative label: Tender gland

Tenderness
type: Class
subclass of: Pain
definition: Discomfort elicited through palpation indicates unusual sensitivity to pressure or touch.
alternative label: Sore to touch
alternative label: Tender pain

Tenesmus
type: Class
subclass of: Abdominal symptom
definition: A painful spasm of the anal sphincter accompanied by an urgent desire to evacuate the bowel or bladder and involuntary straining that results in the passing of little or no matter.

Throat pain
type: Class
subclass of: Throat symptom
definition: Inflammation of the throat, accompanied by dryness and pain.
alternative label: Pain in throat
alternative label: Sore throat
alternative label: Throat soreness

Tight chest
type: Class
subclass of: Chest symptom
subclass of: Circulatory system symptom
alternative label: Chest tightness
alternative label: Feeling of chest tightness
alternative label: Pressure in chest

Toothache
type: Class
subclass of: Mouth symptom
definition: Any pain or soreness within or around a tooth.
alternative label: Dentagra
alternative label: Dentalgia
alternative label: Odontalgia
alternative label: Pain in tooth
alternative label: Tooth pain

Tremor
type: Class
subclass of: General symptom
definition: An involuntary trembling or quivering.
alternative label: Quivering
alternative label: Shaking
alternative label: Trembling

Trismus
type: Class
subclass of: Head symptom
definition: A prolonged tonic spasm of the muscles of the jaw.
alternative label: Lock jaw
alternative label: Lockjaw

Ulcer
type: Class
subclass of: Lesion
definition: A site of damage to the skin or mucous membrane that is characterized by the formation of pus, death of tissue, and is frequently accompanied by an inflammatory reaction.
alternative label: Ulcers

Urinary frequency
type: Class
subclass of: Urinary system symptom
definition: Frequent urination or urgency without an increase in the total daily volume of urine.
alternative label: Increased frequency of micturition
alternative label: Increased frequency of urination
alternative label: Pollakisuria
alternative label: Pollakiuria

Urinary urgency
type: Class
subclass of: Urinary system symptom
definition: The sudden need to urinate.
alternative label: Urgency of micturition
alternative label: Urgency of urination
alternative label: Urgent desire to urinate

Vaginal bleeding
type: Class
subclass of: Reproductive system symptom
alternative label: Abnormal vaginal bleeding
definition: An abnormal condition in which blood is passed from the vagina other than during the menses.

Vaginal discharge
type: Class
subclass of: Reproductive system symptom
definition: Discharge of secretions from the cervical glands of the vagina.
alternative label: Vaginal discharges

Vascular lesion
type: Class
subclass of: Vascular symptom
alternative label: Vascular lesions

Vesicle
type: Class
subclass of: Blister
definition: A small bladder or blister, containing clear fluid.

Vertigo
type: Class
subclass of: Dizziness
definition: A sensation of instability, giddiness, loss of equilibrium, or rotation, caused by a disturbance in the semicircular canal of the inner ear or the vestibular nuclei of the brainstem.
alternative label: Rotary vertigo
alternative label: Rotatory vertigo

Visual disturbance
type: Class
subclass of: Visual symptom
definition: A severe reduction in vision.
alternative label: Disturbance of vision
alternative label: Disturbed vision
alternative label: Visual disturbances
alternative label: Visual impairment

Vomiting
type: Class
subclass of: Abdomen and digestive system symptom
definition: A forceful emptying or throwing up of the stomach contents through the mouth. It can include the complete inability to hold fluids or food in the stomach.
alternative label: Emesis
alternative label: Vomit

Warm skin
type: Class
subclass of: Skin symptom

Watery diarrhea
type: Class
subclass of: Diarrhea
alternative label: Watery diarrhoea

Weight loss
type: Class
subclass of: General symptom
definition: A reduction in body weight.
alternative label: Decreased body weight
alternative label: Loss of weight
alternative label: Weight reduction

Wheezing
type: Class
subclass of: Abnormal breathing
definition: A high-pitched whistling sound associated with labored breathing.
alternative label: Wheeze

Nutritional deficiency
type: Class
subclass of: Food and fluid intake system symptom
definition: A condition of the body that does not get the right amount of the vitamins, minerals, and other nutrients it needs to maintain healthy tissues and organ function.
alternative label: Dietary deficiency
alternative label: Malnutrition
alternative label: Undernutrition

Abdominal distension
type: Class
subclass of: Abdominal symptom

Arthropathy
type: Class
subclass of: Joint symptom
definition: Any disease or abnormal condition affecting a joint.

Conjunctivitis
type: Class
subclass of: Eye symptom
definition: An inflammation or redness of the lining of the white part of the eye and the underside of the eyelid.
alternative label: Conjunctival inflammation

Decreased urination
type: Class
subclass of: Urinary system symptom

Dehydration
type: Class
subclass of: Food and fluid intake system symptom
definition: The loss of water and salts essential for normal body function.

Depression
type: Class
subclass of: Nervous system symptom
definition: A state of being depressed marked especially by sadness, inactivity, difficulty with thinking and concentration.

Double vision
type: Class
subclass of: Visual symptom
alternative label: Diplopia
definition: The medical term for seeing double.

Eyelid redness
type: Class
subclass of: Eyelid symptom

Eyelid tenderness
type: Class
subclass of: Eyelid symptom

Gastric pain
type: Class
subclass of: Gastrointestinal symptom
alternative label: Stomach pain

Hemoptysis
type: Class
subclass of: Respiratory system symptom
alternative label: Coughing up blood
definition: The coughing up of blood or bloody sputum from the lungs or airway.

Meningitis
type: Class
subclass of: Nervous system symptom
definition: A serious inflammation of the meninges, the thin, membranous covering of the brain and the spinal cord.

Nephritis
type: Class
subclass of: Urinary system symptom
definition: Inflammation of the kidney.

Osteomyelitis
type: Class
subclass of: Musculoskeletal system symptom
definition: Inflammation of bone and bone marrow.

Suppurative inflammation
type: Class
subclass of: Inflammation
alternative label: Purulent inflammation

Red eye
type: Class
subclass of: Eye symptom
definition: An eye showing dilation of conjunctival, episcleral or ciliary blood vessels.

Renal failure
type: Class
subclass of: Urinary system symptom
definition: Disorder characterized by the kidney's inability to filter wastes from the blood.
alternative label: Kidney failure

Skin induration
type: Class
subclass of: Skin symptom
alternative label: Induration of skin

Sneezing
type: Class
subclass of: Respiratory system symptom

Spasm
type: Class
subclass of: Musculoskeletal system symptom
definition: A sudden, violent, involuntary muscular contraction.

Swollen mastoid
type: Class
subclass of: Head symptom

Thrombocytopenia
type: Class
subclass of: Hematic system symptom
definition: An abnormal drop in the number of blood cells involved in forming blood clots.
alternative label: Platelet count decreased

Urethritis
type: Class
subclass of: Urinary system symptom
definition: An inflammation of the urethra that is usually caused by an infection.

Vomiting of blood
type: Class
subclass of: Vomiting
alternative label: Hematemesis
definition: Vomiting of bright red blood.