An ontology for describing both infectious disease caused by bacteria and the disease that is related to bacterial infection.
type: Ontology
creator: Nozomi YAMAMOTO
title: PDO: Pathogenic Disease Ontology
version info: Version 0.11
imports: oboInOwl

in_subset
type: AnnotationProperty

has_related_synonym
type: AnnotationProperty

definition
type: AnnotationProperty

subset_property
type: AnnotationProperty

alternative label
type: AnnotationProperty
definition: Section 5. Lexical Labels

Disease involving body sites
type: Class
subclass of: Thing
definition: A disease that located in any part of body.

Disease involving unidentified body site
type: Class
subclass of: Thing
definition: A disease that located in undefined part of body.

Breast disease
type: Class
subclass of: Disease involving body sites
alternative label: Breast disorder
definition: Disease that affects mammary gland.
alternative label: Disorder of breast

Cardiovascular disease
type: Class
subclass of: Disease involving body sites
alternative label: Cardiovascular disorder
alternative label: Circulatory system disease
definition: Disease that affects the heart and blood vessels.
alternative label: Disorder of cardiovascular system

Digestive system disease
type: Class
subclass of: Disease involving body sites
definition: A disease of anatomical entity that is located_in the gastrointestinal tract.
alternative label: Alimentary system disease
alternative label: Digestive system disorder
alternative label: GIT disease
alternative label: Gastroenteropathy
alternative label: Gastrointestinal disease
alternative label: Gastrointestinal disorder

Immune system disease
type: Class
subclass of: Disease involving body sites
definition: A disease of anatomical entity that is located_in the immune system.
alternative label: Disorder of immune system
alternative label: Immunological disease

Musculoskeletal system disease
type: Class
subclass of: Disease involving body sites
definition: Disease that affects muscles, bones, joints, and related structures, such as the tendons and connective tissue.
alternative label: Disorder of musculoskeletal system
alternative label: Musculoskeletal disease
alternative label: Musculoskeletal disorder

Nervous system disease
type: Class
subclass of: Disease involving body sites
definition: A disease of anatomical entity that is located_in the central nervous system or located_in the peripheral nervous system.
alternative label: Nervous system disorder

Reproductive system disease
type: Class
subclass of: Disease involving body sites
definition: A disease of anatomical entity that is located_in reproductive system organs.
has_related_synonym: Genital infection
alternative label: Genital system disease
alternative label: Reproductive system disorder

Respiratory system disease
type: Class
subclass of: Disease involving body sites
definition: A disease of anatomical entity that located_in the respiratory system which extends from the nasal sinuses to the diaphragm.
alternative label: Respiratory disease
alternative label: Respiratory disorder
has_related_synonym: Respiratory infection

Skin disease
type: Class
subclass of: Disease involving body sites
definition: A disease affecting the skin.
alternative label: Disorder of skin
alternative label: Skin and subcutaneous tissue disease
has_related_synonym: Skin infection

Urinary system disease
type: Class
subclass of: Disease involving body sites
definition: A disease of anatomical entity that is located_in kidney, ureter, bladder and urethra.
alternative label: Disorder of the urinary system
has_related_synonym: Urinary infection
alternative label: Urinary tract disease
alternative label: Urological disorder

Systemic disease
type: Class
subclass of: Disease involving body sites
alternative label: Systemic disorder
has_related_synonym: Systemic infection
definition: The infection that is widespread throughout the body and must be assumed to be in all organs.

Acrodermatitis
type: Class
subclass of: Dermatitis
definition: An inflammation of the skin of the hands or feet.

Bartonellosis
type: Class
subclass of: Systemic disease
alternative label: Bartonella Infection
alternative label: Bartonella Infections
alternative label: Guaitara fever
definition: Infections caused by four Bartonella spp. such as B. bacilliformis. There are acute form and chronic form. Symptoms include hemolytic anemia, fever, muscle and joint pain, delirium, coma. The chronic form also has skin lesions.
in_subset: gram-negative bacterial infectious disease

Bile duct disease
type: Class
subclass of: Biliary tract disease
alternative label: Disease of bile duct
definition: Disease that affects the passages that convey bile in and from the liver.

Biliary tract disease
type: Class
subclass of: Hepatobiliary disease
definition: Disease that affects the bile, bile ducts, or gallbladder.

Bladder disease
type: Class
subclass of: Urinary system disease
alternative label: Bladder disorder
alternative label: Disorder of bladder
alternative label: Urinary bladder disease

Blood coagulation disease
type: Class
subclass of: Hematopoietic system disease
alternative label: Blood coagulation disorder
alternative label: Coagulation defect
alternative label: Coagulation disorder
alternative label: Disorder of haemostasis

Bone disease
type: Class
subclass of: Musculoskeletal system disease
definition: Disease that affects the structure or development of bone or causes an impairment of normal bone function.
alternative label: Disorder of bone
alternative label: Skeletal disease

Bone inflammation disease
type: Class
subclass of: Bone disease
definition: A bone disease that results_in inflammation of the located_in bone.
alternative label: Bone inflammatory disease
alternative label: Inflammatory disorder of bone
alternative label: Osteitis

Brain disease
type: Class
subclass of: Central nervous system disease
alternative label: Encephalopathy

Bronchial disease
type: Class
subclass of: Lung disease
definition: A lung disease that affects the airways leading into the lungs, which is caused due to inflammation of the bronchi and bronchioles, infection, or blockage.
alternative label: Bronchial disorder
alternative label: Disorder of bronchus

Central nervous system disease
type: Class
subclass of: Nervous system disease
definition: A nervous system disease that affects either the spinal cord (myelopathy) or brain (encephalopathy) of the central nervous system.
alternative label: Disorder of central nervous system

Cholangitis
type: Class
subclass of: Bile duct disease
definition: An inflammation of the bile duct.

Colonic disease
type: Class
subclass of: Intestinal disease
alternative label: Colon disorder
definition: Disease that affects the part of the large intestine extending from the cecum to the rectum.
alternative label: Disorder of colon

Connective tissue disease
type: Class
subclass of: Soft tissue disease
alternative label: Connective tissue disorder
definition: Disease that affects tissue that supports and binds other body tissue and parts.
alternative label: Disorder of connective tissue

Crohn's disease
type: Class
subclass of: Inflammatory bowel disease
definition: A chronic inflammatory disorder. The most common symtoms include diarrhea, abdominal pain, fever, and weight loss.
alternative label: Crohn disease
alternative label: Granulomatous enteritis
has_related_synonym: Regional enteritis

Demyelinating disease
type: Class
subclass of: Neurodegenerative disease
definition: Any condition characterized by destruction of the myelin sheaths of nerves.
alternative label: Demyelinating disorder

Dermatitis
type: Class
subclass of: Skin disease
definition: An inflammation of the skin. Most types of dermatitis are characterized by an itchy pink or red rash.
alternative label: Inflammation of skin
alternative label: Skin inflammation

Auditory system disease
type: Class
subclass of: Sensory system disease
alternative label: Disorder of ear and mastoid
alternative label: Ear and mastoid disease
alternative label: Ear disease
alternative label: Ear disorder

Eye and adnexa disease
type: Class
subclass of: Sensory system disease
alternative label: Disorder of ocular adnexa
has_related_synonym: Ocular infection

Eyelid disease
type: Class
subclass of: Skin disease
alternative label: Disorder of eylid
alternative label: Eyelid disorder

Fasciitis
type: Class
subclass of: Connective tissue disease
definition: An inflammation of a fascia.

Female reproductive system disease
type: Class
subclass of: Reproductive system disease
alternative label: Disorder of female genital system
alternative label: Female genital disease

Gallbladder disease
type: Class
subclass of: Biliary tract disease
alternative label: Gallbladder disorder

Gingival disease
type: Class
subclass of: Periodontal disease
definition: Any disease of the gingivae.
alternative label: Gingival disorder
alternative label: Gum disease

Globe disease
type: Class
subclass of: Eye and adnexa disease
alternative label: Disease of eyeball
alternative label: Disorder of globe
alternative label: Eye disorder

Heart disease
type: Class
subclass of: Cardiovascular disease
definition: A structural or functional abnormality of the heart, or of the blood vessels supplying the heart.
alternative label: Cardiac disorder
alternative label: Heart disorder

Hematopoietic system disease
type: Class
subclass of: Immune system disease
alternative label: Blood disease
alternative label: Blood disorder
alternative label: Disease of hematopoietic system
alternative label: Hematological disease

Hemorrhagic disease
type: Class
subclass of: Thrombophilia
alternative label: Hemorrhagic disorder

Hepatobiliary disease
type: Class
subclass of: Digestive system disease
definition: Disease that affects the liver, bile ducts and gallbladder.
alternative label: Hepatobiliary disorder
alternative label: Hepatobiliary tract disease
alternative label: Liver and biliary tract disease

Inflammatory bowel disease
type: Class
subclass of: Intestinal disease
definition: Intestine becomes inflamed, often causing abdominal cramps and diarrhea. there are two types of disease; Crohn's disease and ulcerative disease.

Interstitial lung disease
type: Class
subclass of: Lung disease
alternative label: ILD
alternative label: Interstitial pneumonias

Intestinal disease
type: Class
subclass of: Digestive system disease
definition: Disease that affects from small intestine to large intestine.
alternative label: Disorder of intestine
alternative label: Enteropathy

Kidney disease
type: Class
subclass of: Urinary system disease
alternative label: Renal disorder

Lower respiratory tract disease
type: Class
subclass of: Respiratory system disease
definition: A respiratory system disease which involves the lower respiratory tract such as the trachea, bronchial tree, lungs, pulmonary vessels and pleura.
alternative label: Disorder of lower respiratory system

Lung disease
type: Class
subclass of: Lower respiratory tract disease
definition: A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide.
alternative label: Disorder of lung
alternative label: Lung disorder
has_related_synonym: Pulmonary infection

Lymph node disease
type: Class
subclass of: Lymphatic system disease
alternative label: Lymph node disorder

Lymphatic system disease
type: Class
subclass of: Immune system disease
alternative label: Disease of lympoid system
definition: Disease that affects lymphatic vessels and lymphoid tissue.
alternative label: Disorder of lymphatic system
alternative label: Lymphatic disease
alternative label: Lymphatic disorder
alternative label: Lympoid system disease

Middle ear disease
type: Class
subclass of: Auditory system disease
alternative label: Disorder of middle ear
alternative label: Middle ear disorder

Mouth disease
type: Class
subclass of: Digestive system disease
alternative label: Mouth disorder
alternative label: Oral disorder
has_related_synonym: Oral infection

Muscular disease
type: Class
subclass of: Musculoskeletal system disease
alternative label: Muscle disorder

Myopathy
type: Class
subclass of: Muscular disease
definition: A muscular disease in which the muscle fibers do not function resulting in muscular weakness.
alternative label: Myopathic disease

Nephritis
type: Class
subclass of: Kidney disease
definition: An inflammation of the kidney.

Neurodegenerative disease
type: Class
subclass of: Central nervous system disease
definition: A central nervous system disease that results_in the progressive deterioration of tissue or organ function or structure, whether due to normal bodily wear or lifestyle choices.
alternative label: Degenerative disease
alternative label: Neurodegenerative disorder

Nose disease
type: Class
subclass of: Upper respiratory tract disease
alternative label: Disorder of the nose
alternative label: Nasal disorder

Obstructive lung disease
type: Class
subclass of: Lung disease
alternative label: Respiratory airway obstruction

Paranasal sinus disease
type: Class
subclass of: Nose disease
alternative label: Disorder of nasal sinus
alternative label: Paranasal sinus disorder

Peptic ulcer
type: Class
subclass of: Digestive system disease
definition: An ulceration of the mucous membrane of the esophagus, stomach, or duodenum, due to action of the acid gastric juice.
alternative label: Gastroduodenal ulcer
alternative label: Peptic ulcer disease
alternative label: Peptic ulceration

Peripheral nervous system disease
type: Class
subclass of: Nervous system disease
definition: Disease that affects all elements of the nervous system outside the brain and spinal cord.
alternative label: Peripheral nerve disease
alternative label: Peripheral nervous system disorder
alternative label: Peripheral neuropathy

Periodontal disease
type: Class
subclass of: Tooth disease
alternative label: Disease of supporting structures of teeth
definition: Diseases that affect the tissues that support and anchor the teeth.
alternative label: Periodontal disorder
has_related_synonym: Periodontal infection
alternative label: Periodontium disorder

Pneumonitis
type: Class
subclass of: Lung disease
definition: An inflammation of lung tissue.

Placenta disease
type: Class
subclass of: Uterine disease
alternative label: Disorder of placenta
alternative label: Placenta disorder

Pregnancy complication
type: Class
subclass of: Pregnancy disease

Pregnancy disease
type: Class
subclass of: Female reproductive system disease
alternative label: Disease of pregnancy
alternative label: Disorder of pregnancy
alternative label: Pregnancy disorder

Primary immunodeficiency disease
type: Class
subclass of: Immune system disease
definition: An immune system disease that results when one or more essential parts of the immune system is missing or not working properly at birth due to a genetic mutation.
alternative label: Immune deficiency disorder
alternative label: Immunodeficiency disorder
alternative label: Immunodeficiency syndrome

Rectal disease
type: Class
subclass of: Colonic disease
definition: Disease that affects rectum.
alternative label: Disorder of rectum

Relapsing fever
type: Class
subclass of: Systemic disease
definition: A primary bacterial infectious disease that results_in infection, has_material_basis_in Borrelia, which is transmitted_by tick or transmitted_by body louse.
alternative label: Recurrent fever
alternative label: Relapsing fevers
in_subset: gram-negative bacterial infectious disease

Scarlet fever
type: Class
subclass of: Systemic disease
definition: An acute contagious disease caused by Group A bacteria of the genus Streptococcus or Staphylococcus. It is characterized by fever, sore throat, rash. Staphylococcal scarlet fever is a mild form of scarlet fever.
alternative label: Scarlatina

Sebaceous gland disease
type: Class
subclass of: Skin disease
alternative label: Disorder of sebaceous gland

Sensory system disease
type: Class
subclass of: Nervous system disease
definition: A body system disease which is located in a part of the nervous system responsible for processing sensory information that consists of sensory receptors, neural pathways, and parts of the brain involved in sensory perception. Commonly recognized sensory systems are those for vision, hearing, somatic sensation (touch), taste and olfaction (smell).
alternative label: Neurosensory Disorder
alternative label: Sensory disorder
alternative label: Sensory disturbance

Soft tissue disease
type: Class
subclass of: Musculoskeletal system disease
alternative label: Soft tissue diseases
alternative label: Soft tissue disorder

Stomach disease
type: Class
subclass of: Digestive system disease
alternative label: Gastric disease
alternative label: Gastropathy
alternative label: Stomach disorder

Surgical wound infection
type: Class
subclass of: Wound infection
definition: Infectious disease associated with wound during surgical procedure.

Hard tissue teeth disease
type: Class
subclass of: Tooth disease
alternative label: Disease of hard tissues of teeth

Thrombophilia
type: Class
subclass of: Blood coagulation disease
definition: A disorder of the hemopoietic system in which there is an increased tendency for thrombosis.
alternative label: Hypercoagulability

Tooth disease
type: Class
subclass of: Mouth disease
alternative label: Dental disorder

Upper respiratory tract disease
type: Class
subclass of: Respiratory system disease
definition: A respiratory system disease which involves the upper respiratory tract such as the nose, nasal cavity, ethmoidal air cells, frontal sinuses, sphenoidal sinuses, maxillary sinus, larynx, and trachea.
alternative label: Disorder of upper respiratory system

Urethral disease
type: Class
subclass of: Urinary system disease
alternative label: Urethra disease
alternative label: Urethra disorder

Uterine disease
type: Class
subclass of: Female reproductive system disease
alternative label: Disorder of uterus
alternative label: Uterine disorder
alternative label: Uterus disorder

Vaginal disease
type: Class
subclass of: Female reproductive system disease
alternative label: Vagina disorder
alternative label: Vaginal disorder

Vaginitis
type: Class
subclass of: Vaginal disease
alternative label: Inflammation of vagina

Vascular disease
type: Class
subclass of: Cardiovascular disease
definition: Disease that affects the vessels of the body, especially the arteries and veins.

Vasculitis
type: Class
subclass of: Vascular disease
definition: A vascular disease that is an inflammatory destruction of blood vessels.
alternative label: Angiitis

Vein disease
type: Class
subclass of: Vascular disease
definition: Disease that affects blood vessels.
alternative label: Disorder of vein

Wound infection
type: Class
subclass of: Disease involving unidentified body site
definition: Infectious disease associated with wound.

Abortion
type: Class
subclass of: Pregnancy complication
definition: The spontaneous or induced termination of pregnancy before the fetus has developed to the stage of viability.

Acne
type: Class
subclass of: Sebaceous gland disease
definition: A skin condition characterized by pimples on the face, chest, and back. The cause may diet, gut flora, allergies. Symptoms include pain, tenderness, and itching on inflamed site.
alternative label: Acne vulgaris

Acrodermatitis chronica atrophicans
type: Class
subclass of: Acrodermatitis
definition: A late manifestation of Lyme disease especially when untreated and is characterized by erythematous and edematous lesions. Common symptoms are skin lesion, peripheral neuropathy, and arthropathy.
alternative label: Dermatitis atrophicans
alternative label: Dermatitis chronica atrophicans

Actinomycetoma
type: Class
subclass of: Skin disease
definition: A chronic granulomatous inflammation involving the deep dermis and the subcutaneous tissues. It is caused by Actinomycetes bacteria.
alternative label: Actinomycotic mycetoma
in_subset: gram-positive bacterial infectious disease

African tick-bite fever
type: Class
subclass of: Spotted fever
definition: A spotted fever that has_material_basis_in Rickettsia africae, which is transmitted_by ticks (Amblyomma hebraeum and Amblyomma variegatum). The infection has fever, headache, myalgia, and regional lymphadenitis.
alternative label: Rickettsia africae spotted fever
alternative label: South african tick-bite fever
in_subset: gram-negative bacterial infectious disease
in_subset: tick-borne infectious disease
in_subset: zoonotic infectious disease

Human granulocytic anaplasmosis
type: Class
subclass of: Ehrlichiosis
definition: An ehrlichiosis that results_in infection located_in granular leukocyte, has_material_basis_in Anaplasma phagocytophilum, which is transmitted_by lone start tick (Amblyomma americanum ). The infection has fever, chills, headache, and muscle aches.
alternative label: HGE
alternative label: Human anaplasmosis due to Anaplasma phagocytophilum
alternative label: Human granulocytic ehrlichiosis
in_subset: gram-negative bacterial infectious disease
in_subset: tick-borne infectious disease

Anthrax
type: Class
subclass of: Disease involving unidentified body site
alternative label: Anthrax disease
alternative label: Charbon
alternative label: Infection due to Bacillus anthracis
alternative label: Milzbrand
definition: an infection caused by the bacterium Bacillus anthracis that primarily affects livestock but that can occasionally spread to humans. It affects affecting either the skin, intestines, or lungs. Cutaneous anthrax is most common type of anthrax. Symptoms vary depending on how the disease was contracted including fever, fatigue, headache, muscle aches, abdominal pain, bloody diarrhea, dyspnea, and hematemesis.
in_subset: gram-positive bacterial infectious disease
in_subset: zoonotic infectious disease

Arthritis
type: Class
subclass of: Bone inflammation disease
definition: A bone inflammation disease that involves a response to irritation or injury, characterized by joint pain and swelling.
alternative label: Inflammatory disorder of joint

Asthma
type: Class
subclass of: Bronchial disease
subclass of: Obstructive lung disease
definition: A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. Common symptoms include wheezing, cough, shortness of breath, and dyspnea.
alternative label: Bronchial asthma
alternative label: Hyperreactive airway disease

Bacillary angiomatosis
type: Class
subclass of: Skin disease
definition: An infection caused by Bartonella quintana and B. henselae. Symptoms include proliferating blood vessels, forming nodules, lesion, and tumor.
alternative label: Epithelioid angiomatosis
in_subset: gram-negative bacterial infectious disease

Bacteremia
type: Class
subclass of: Vascular disease
definition: An invasion of the bloodstream by bacteria. Bacteremia may cause no symptoms and resolve without treatment, or it may produce fever and other symptoms of infection.
alternative label: Bacteraemia

Bacterial vaginosis
type: Class
subclass of: Vaginitis
definition: A bacterial infectious disease that is associated with a grayish vaginal discharge usually of foul odor and the presence of Gardnerella vaginalis.
alternative label: Nonspecific vaginosis

Blindness
type: Class
subclass of: Eye and adnexa disease
definition: Lack or loss of ability to see.

Botulism
type: Class
subclass of: Disease involving unidentified body site
definition: A primary bacterial infectious disease that involves intoxication caused by botulinum neurotoxins (BoNTA, B, E and F) located_in neuromuscular junction, resulting in descending muscle paralysis, has_material_basis_in Clostridium botulinum A, has_material_basis_in Clostridium botulinum B, has_material_basis_in Clostridium botulinum E and has_material_basis_in Clostridium botulinum F.
alternative label: Botulism poisoning
alternative label: Foodborne botulism
alternative label: Infection due to Clostridium botulinum
in_subset: gram-positive bacterial infectious disease

Brain abscess
type: Class
subclass of: Brain disease
definition: A bacterial infection within the brain. The symptoms are headache, seizures, drowsiness, and altered mental status.
alternative label: Cerebral abscess

Bronchiolitis
type: Class
subclass of: Lung disease
definition: A lung disease that is an inflammation of the bronchioles, the smallest air passages of the lungs. It is caused by viruses and bacteria.

Bronchitis
type: Class
subclass of: Bronchial disease
subclass of: Obstructive lung disease
definition: A bronchial disease that is an inflammation of the bronchial tubes. It is caused by bacteria and viruses. The symptoms include runny nose, dry cough, low-grade fever, fatigue, and sore throat.
has_related_synonym: Bronchial infection

Bronchopulmonary infection
type: Class
subclass of: Lower respiratory tract disease
definition: An infection associated with the bronchi and lungs.
alternative label: Bronchopulmonary disease

Brucellosis
type: Class
subclass of: Systemic disease
definition: A primary bacterial infectious disease that is caused by the bacteria of the genus Brucella, when humans come in contact with contaminated animals or animal products or ingestion of infected food products. The symptoms include fever, sweating, depression, muscle pain, chills, and weakness.
alternative label: Gibraltar fever
alternative label: Malta fever
alternative label: Mediterranean fever
alternative label: Undulant fever
alternative label: Undulant fevers
in_subset: gram-negative bacterial infectious disease
in_subset: zoonotic infectious disease

Bubonic plague
type: Class
subclass of: Lymphatic system disease
definition: A plague that results_in infection located_in lymph node producing a bubo, which is an inflamed, necrotic, and hemorrhagic lymphoid tissue. The infection has high fever, tachycardia, hypotension, delirium, and swelling of the lymph nodes.
alternative label: Black death
in_subset: gram-negative bacterial infectious disease
in_subset: zoonotic infectious disease

Buruli ulcer
type: Class
subclass of: Skin disease
definition: A primary bacterial infectious disease that results_in infection located_in skin or located_in subcutaneous tissue, has_material_basis_in Mycobacterium ulcerans, which could be transmitted_by insects. The bacterium produces a toxin, named mycolactone, which causes subcutaneous fat necrosis and inhibits an immune response. Symptoms are nodule formation and skin ulcer.
alternative label: Bairnsdale ulcer
alternative label: Daintree ulcer
alternative label: Mossman ulcer
alternative label: Searl ulcer
alternative label: Searle's ulcer
in_subset: gram-positive bacterial infectious disease

Carrion's disease
type: Class
subclass of: Bartonellosis
definition: A primary bacterial infectious disease that results_in infection located_in endothelial cells or located_in red blood cells, has_material_basis_in Bartonella bacilliformis, which is transmitted_by sandflies of genus Lutzomyia. The infection has acute and chronic phases. The acute phase is characterized by severe hemolytic anemia and transient immunosuppression. The chronic phase is characterized by verruga peruana lesions which may ulcerate and bleed.
alternative label: Oroya fever
in_subset: gram-negative bacterial infectious disease

Cavitary pneumonia
type: Class
subclass of: Pneumonia
definition: A disease in which the normal lung architecture is replaced by a cavity. In the healthy lung, oxygen transport occurs at the level of the alveoli which has an average size of 0.1 mm.

Cepacia syndrome
type: Class
subclass of: Respiratory system disease
definition: An almost universally fatal necrotizing pneumonia. B. cenocepacia and B. multivorans are the species most commonly implicated in causing cepacia syndrome.
alternative label: Burkholderia cepacia complex infection
in_subset: gram-negative bacterial infectious disease

Chancroid
type: Class
subclass of: Reproductive system disease
definition: A primary bacterial infectious disease that is a sexually transmitted infection located_in skin of the genitals, has_material_basis_in Haemophilus ducreyi, which is transmitted_by sexual contact. The infection has papule, ulcer, and enlarged lymph nodes.
alternative label: Chancroidal bubo
alternative label: Ducrey's chancre
alternative label: Ulcus molle
in_subset: gram-negative bacterial infectious disease
in_subset: sexually transmitted infectious disease

Cholecystitis
type: Class
subclass of: Gallbladder disease
definition: An inflammation of the gallbladder. Symptoms include fever, nausea, vomiting, and abdominal pain.

Cholera
type: Class
subclass of: Intestinal disease
definition: A primary bacterial infectious disease that is described as an acute, diarrheal illness caused by infection of the intestine with the bacterium Vibrio cholerae, which is characterized by profuse watery diarrhea, vomiting, muscle cramp, and dehydration.
alternative label: Vibrio cholerae infection
in_subset: gram-negative bacterial infectious disease

Chorioamnionitis
type: Class
subclass of: Placenta disease
definition: A placenta disease that is an inflammation of the fetal membranes (amnion and chorion) due to a bacterial infection. Symptoms include fever, uterine tenderness, tachycardia, and vaginal discharge. There may be no significant sign.
alternative label: Membranitis

Chronic bronchitis
type: Class
subclass of: Bronchitis
definition: Ongoing inflammation that eventual results in narrowing of the airways. Symptoms include cough, phlegm, and wheezing.

Chronic granulomatous disease
type: Class
subclass of: Primary immunodeficiency disease
definition: A failure of patients' phagocytic cells to kill ingested bacteria. It is characterized by suppurative lymphadenitis, hepatosplenomegaly, pneumonia, and hematologic evidence of chronic infection.
alternative label: Chronic granulomatous

Colitis
type: Class
subclass of: Colonic disease
definition: Inflammation of the colon. Main Symptom is diarrhea.

Cystic fibrosis
type: Class
subclass of: Disease involving unidentified body site
definition: An inherited disease that affects the lungs, digestive system, sweat glands, and male fertility.
alternative label: CF
alternative label: Fibrocystic disease
alternative label: Mucoviscidosis

Cystitis
type: Class
subclass of: Bladder disease
definition: An inflammation of the urinary bladder that is a common female problem. Symptoms include dysuria, urinary urgency, and urinary frequency.

Dental caries
type: Class
subclass of: Hard tissue teeth disease
definition: A tooth disease caused by the complex interaction of food, especially starches and sugars, with the bacteria that form dental plaque. Tooth pain occurs after decay reaches the inside of the tooth.
alternative label: Caries
alternative label: Tooth decay

Diarrhea
type: Class
subclass of: Intestinal disease
definition: Diarrhea is a intestinal disease described as the condition of having frequent loose or liquid bowel movements. Acute diarrhea is a common cause of death in developing countries and the second most common cause of infant deaths worldwide. The loss of fluids through diarrhea can cause severe dehydration which is one cause of death in diarrhea sufferers. Along with water, sufferers also lose dangerous amounts of important salts, electrolytes, and other nutrients. There are at least four types of diarrhea: secretory diarrhea, osmotic diarrhea, motility-related diarrhea, and inflammatory diarrhea.
alternative label: Diarrhoea
alternative label: Loose bowel movement

Diphtheria
type: Class
subclass of: Upper respiratory tract disease
definition: A primary bacterial infectious disease caused by Corynebacterium diphtheriae. The produced toxins destroys healthy tissue in the upper area of the throat around the tonsils, or in open wounds in the skin. The signs and symptoms of diphtheria vary according to the location of the infection. Main symptoms are sore throat, fever, and difficulty breathing.
in_subset: gram-positive bacterial infectious disease

Disseminated intravascular coagulation
type: Class
subclass of: Hemorrhagic disease
definition: A serious medical condition that develops when the normal balance between bleeding and clotting is disturbed. Excessive bleeding and clotting injures body organs, and causes anemia or death.
alternative label: Consumptive coagulopathy
alternative label: DIC syndrome
alternative label: Defibrination syndrome
alternative label: Diffuse or disseminated intravascular coagulation

Dysentery
type: Class
subclass of: Colonic disease
definition: An intestinal infectious disease that involves inflammation of the intestines, especially colon, due to chemical irritants, bacteria, protozoa, or parasitic worms, which results in watery diarrhea, abdominal cramps, abdominal pain, tenesmus, fever, and bloody stool.
comment: Dysenteria
alternative label: Infectious diarrhea

Ehrlichiosis
type: Class
subclass of: Systemic disease
definition: A primary bacterial infectious disease that results_in infection located_in leukocyte, has_material_basis_in Ehrlichia chaffeensis or Anaplasma phagocytophilum, which are transmitted_by lone start stick and transmitted_by black-legged tick respectively. Symptoms include fever, chills, headache, muscle ache, and malaise.
alternative label: Erlichiosis
alternative label: Human ehrlichiosis
in_subset: gram-negative bacterial infectious disease
in_subset: tick-borne infectious disease

Encephalitis
type: Class
subclass of: Brain disease
definition: A nervous system infectious disease characterized as an acute inflammation of the brain. The usual cause is a viral infection, but bacteria can also cause it. Cases can range from mild to severe. For mild cases, symptom is flu-like including headache, fever, nausea, and vomiting. Serious cases can cause drowsiness, confusion, and seizures.

Endocarditis
type: Class
subclass of: Heart disease
definition: An infectious inflammation of the endocardium (inner layer of the heart) and heart valves.

Enteritis necroticans
type: Class
subclass of: Enteritis
definition: A segmental necrotizing infection of the jejunum and ileum caused by Clostridium perfringens, Type C. Symptoms include abdominal pain, bloody diarrhea, and vomiting.
alternative label: Clostridial necrotizing enteritis
alternative label: Pigbel
in_subset: gram-positive bacterial infectious disease

Enterocolitis
type: Class
subclass of: Intestinal disease
definition: An inflammation of the mucous membrane of both the small and large intestine.
alternative label: Coloenteritis

Epidemic typhus
type: Class
subclass of: Rickettsiosis
subclass of: Typhus
definition: A typhus that has_material_basis_in Rickettsia prowazekii, which is transmitted_by human body louse (Pediculus humanus corporis). Common symptoms are high fever, headache, chills, and rash.
alternative label: Classical typhus
alternative label: Epidemic louse-borne typhus fever
alternative label: European typhus
alternative label: Louse-borne typhus
alternative label: Sylvatic typhus
in_subset: gram-negative bacterial infectious disease
in_subset: zoonotic infectious disease

Erysipelas
type: Class
subclass of: Dermatitis
definition: A skin infection caused by Group A Streptococci. General symptoms are high fever, chills, skin redness, and skin swelling.
in_subset: gram-positive bacterial infectious disease

Farmer's lung
type: Class
subclass of: Extrinsic allergic alveolitis
definition: An extrinsic allergic alveolitis which is induced by the inhalation of spores (Aspergillus sp and thermophilic actinomycetes) in dust from moldy hay or straw. It is characterized by fever, cough, chills, and shortness of breath.
alternative label: Harvester's lung
alternative label: Haymaker's lung
alternative label: Moldy hay disease
alternative label: Mouldy hay disease

Endemic typhus
type: Class
subclass of: Typhus
subclass of: Flea-borne spotted fever
definition: A comparatively mild, acute, endemic form of typhus caused by the microorganism Rickettsia typhi, transmitted from rats to humans by fleas and characterized by fever, headache, and muscular pain.
alternative label: Endemic typhus fever
alternative label: Murine endemic flea typhus
alternative label: Murine typhus
alternative label: Urban typhus
in_subset: gram-negative bacterial infectious disease
in_subset: zoonotic infectious disease

Food poisoning
type: Class
subclass of: Digestive system disease
alternative label: Foodborne disease
definition: General term for health problems arising from eating food contaminated by bacteria, viruses, environmental toxins, or toxins present within the food itself. Symptoms of food poisoning usually involve diarrhea, abdominal cramp, vomiting, and fever. Some food-borne toxins can affect the nervous system.

Furunculosis
type: Class
subclass of: Skin disease
definition: An acute skin disease characterized by boils or successive crops of boils that are caused by staphylococci or streptococci.
alternative label: Boil

Gas gangrene
type: Class
subclass of: Muscular disease
definition: A commensal bacterial infectious disease that results_in infection, located_in muscle tissue, has_material_basis_in Clostridium perfringens, which produce gas that becomes trapped in the infected tissue. Gas gangrene usually develops after injuries or surgery. The infection has severe pain, swelling, tachycardia, and blister.
alternative label: Clostridial myonecrosis
alternative label: Gas bacillus infection
alternative label: Malignant edema
alternative label: Progressive emphysematous necrosis
in_subset: gram-positive bacterial infectious disease

Gastric ulcer
type: Class
subclass of: Peptic ulcer
subclass of: Stomach disease
definition: An ulcer of an area of the gastrointestinal tract that is usually acidic and thus extremely painful. It is characterized by vomiting of blood and gastric pain.
alternative label: Gastric ulceration
alternative label: Pylorus ulcer
alternative label: Stomach ulcer

Gastritis
type: Class
subclass of: Stomach disease
definition: An inflammation of the lining of the stomach with symptom of burning or discomfort in stomach. True gastritis caused by Helicobacter pylori. Symptoms of H. pylori gastritis include abdominal pain and reduced acid secretion in the stomach.
alternative label: Gastric catarrh
alternative label: Gastric inflammation

Gastroenteritis
type: Class
subclass of: Digestive system disease
definition: A gastrointestinal system infectious disease that involves inflammation of the lining of the stomach and small and large intestines, which is caused by viruses, bacteria, or parasites. Chemicals and drugs also cause gastroenteritis. The symptoms include diarrhea, nausea, vomiting, and abdominal pain.
alternative label: Gastroenteropathy

Genital ulcer
type: Class
subclass of: Reproductive system disease
definition: An ulcer located on the genital area, usually caused by a sexually transmitted disease such as genital herpes, syphilis, chancroid, or thrush.
alternative label: Genital ulcer disease
alternative label: Genital ulceration

Gingivitis
type: Class
subclass of: Gingival disease
alternative label: Gum inflammation
definition: Inflammation of the gums, seen as painless bleeding during brushing and flossing.
alternative label: Red gums

Glanders
type: Class
subclass of: Lung disease
definition: A primary bacterial infectious disease that results_in septicemic infection, has_material_basis_in Burkholderia mallei, which is transmitted_by contact with tissues or body fluids of infected animals, or through mucosal surfaces such as the eyes and nose. Symptoms include purulent inflammation and nodule formation.
alternative label: Farcy
alternative label: Farcy cords
alternative label: Farcy pipes
alternative label: Maliasmus
in_subset: gram-negative bacterial infectious disease
in_subset: zoonotic infectious disease

Glomerulonephritis
type: Class
subclass of: Nephritis
definition: An inflammatory disease of both kidneys. Acute form most often follows a streptococcal infection of the throat or skin. It is characterized by hematuria, proteinuria, edema, and decreased urine production.
prior version: UMLS_CUI:C0017658

Gonorrhea
type: Class
subclass of: Reproductive system disease
definition: A primary bacterial infectious disease that is a sexually transmitted infection, located_in uterus, located_in fallopian tube, located_in urethra, located_in mouth, located_in throat, located_in eye or located_in anus, has_material_basis_in Neisseria gonorrhoeae, which is transmitted_by contact with the penis, vagina, mouth, or anus or transmitted_by congenitally from mother to baby during delivery. The infection has abdominal pain, pain during urination, burning with urination, vaginal discharge, discharge from penis, urination frequency, and urethritis.
alternative label: Gonococcal infection
alternative label: Gonorrhoea
in_subset: gram-negative bacterial infectious disease
in_subset: sexually transmitted infectious disease

Haverhill fever
type: Class
subclass of: Rat-bite fever
definition: A primary bacterial infectious disease that results_in infection, has_material_basis_in Streptobacillus moniliformis, which is transmitted_by contact with urine or secretions from the mouth, eye, or nose of an infected animal or transmitted_by bite of an infected animal, especially rat. Symptoms are fever, chills, and joint pain.
alternative label: Epidemic arthritic erythema
alternative label: Streptobacillary rat-bite fever
alternative label: Streptobacillosis
in_subset: gram-negative bacterial infectious disease
in_subset: zoonotic infectious disease

Hemorrhagic colitis
type: Class
subclass of: Colitis
subclass of: Food poisoning
definition: An infectious disease that involves infection of the large intestine caused by a serological subgroup of Escherichia coli called enterohemorrhagic Escherichia coli (EHEC). EHEC are considered to be moderately invasive and are characterized by the production of verotoxin or Shiga toxins. The infection results in abdominal cramp and bloody diarrhea.
alternative label: E. coli hemorrhagic colitis
in_subset: gram-negative bacterial infectious disease

Hepatitis
type: Class
subclass of: Liver disease
definition: An inflammation of the liver, with accompanying liver cell damage or cell death, caused most frequently by viral infection, but also by certain drugs, chemicals, or poisons. Symptoms include jaundice, nausea, vomiting, muscle pain, and joint pain.
alternative label: Hepatic inflammation
alternative label: Inflammatory disease of liver

Erysipeloid
type: Class
subclass of: Skin disease
definition: A primary bacterial infectious disease that results_in infection located_in skin, has_material_basis_in Erysipelothrix rhusiopathiae, which is transmitted_by contact with infected animals. The infection has skin lesions, fever, and headache.
alternative label: Erysipeloids
alternative label: Rosenbach erysipeloid
in_subset: gram-positive bacterial infectious disease
in_subset: zoonotic infectious disease

Human monocytic ehrlichiosis
type: Class
subclass of: Ehrlichiosis
definition: An ehrlichiosis that results_in infection located_in monocyte or located_in macrophage, has_material_basis_in Ehrlichia chaffeensis, which is transmitted_by black-legged tick (Ixodes scapularis), transmitted_by western black-legged tick (Ixodes pacificus) or transmitted_by castor bean tick (Ixodes ricinus,). The symptoms are fever, chills, headache, and body pain.
alternative label: Ehrlichiosis chafeensis
in_subset: gram-negative bacterial infectious disease
in_subset: tick-borne infectious disease

Extrinsic allergic alveolitis
type: Class
subclass of: Interstitial lung disease
alternative label: Allergic alveolitis
alternative label: Alveolitis
definition: An interstitial lung disease involving inflammation of alveoli and smallest airways (bronchioles) of the lung caused by an allergic reaction to inhaled organic dusts containing microorganisms or proteins, and chemicals. Symptoms include cough, fever, chest tightness, malaise, chills, dyspnea, and muscle aches.
alternative label: Hypersensitivity pneumonitis

Ileal Crohn's disease
type: Class
subclass of: Colonic disease
subclass of: Crohn's disease
definition: Crohn's disease occurred in ileum.
alternative label: Crohn's disease of ileum

Impetigo
type: Class
subclass of: Pyoderma
definition: A very localized bacterial infection of the skin caused by Streptococcus aureus or hemolytic staphylococci. Vesicle and itching are main symptom, and there is no pain and redness.
alternative label: Impetigo contagiosa

Infectious abortion
type: Class
subclass of: Abortion

Infertility
type: Class
subclass of: Reproductive system disease
alternative label: Infertile
alternative label: Sterile
definition: The biological failure of a couple to conceive a pregnancy.

Lactococcosis
type: Class
subclass of: Systemic disease
definition: A bacterial disease that produces hyperacute and hemorrhagic septicemia in various cultured fish species caused by Lactococcus garvieae. L. garvieae has recently been associated with an increasing number of human infections, such as endocarditis, septicemia, liver abscess, secondary peritonitis, spondylodiscitis, and diverticulitis.
in_subset: gram-positive bacterial infectious disease

Legionellosis
type: Class
subclass of: Respiratory system disease
definition: A primary bacterial infectious disease that results_in infection located_in respiratory tract, has_material_basis_in Legionella pneumophila, which is transmitted_by inhalation of droplets containing bacteria.
alternative label: Legionella infection
in_subset: gram-negative bacterial infectious disease

Legionnaires' disease
type: Class
subclass of: Legionellosis
definition: A legionellosis that is characterized by severe form of infection producing pneumonia. Symptoms include high fever, chills, muscle aches, headache, and dry cough.
alternative label: Legionnaire disease
alternative label: Legionnaire's disease
in_subset: gram-negative bacterial infectious disease

Leprosy
type: Class
subclass of: Skin disease
subclass of: Peripheral nervous system disease
definition: A primary bacterial infectious disease that results_in infection located_in superficial peripheral nerves, located_in skin, located_in mucous membranes of the upper respiratory tract, located_in anterior chamber of the eyes, or located_in testes, has_material_basis_in Mycobacterium leprae, which is transmitted_by aerosol spread from infected nasal secretions to exposed nasal and oral mucosa. Symptoms may include skin lesion, deformity, peripheral edema, and muscle weakness.
alternative label: Hansen's disease
in_subset: gram-positive bacterial infectious disease

Leptospirosis
type: Class
subclass of: Systemic disease
definition: A primary bacterial infectious disease that involves systemic infection, has_material_basis_in Leptospira, which is transmitted_by contact with water, food, or soil containing urine from the infected animals. The infection has fever, headache, chills, jaundice, nausea, vomiting, meningitis, and nephritis.
alternative label: Harvest fever
alternative label: Mud fever
alternative label: Pretibial fever
alternative label: Seven day fever
alternative label: Spirochetal jaundice
alternative label: Swamp fever
in_subset: gram-negative bacterial infectious disease
in_subset: zoonotic infectious disease

Listeriosis
type: Class
subclass of: Central nervous system disease
definition: A primary bacterial infectious disease that results_in infection, has_material_basis_in Listeria monocytogenes, which is transmitted_by ingestion of contaminated food or raw milk or transmitted_by congenital method. Symptoms include fever, nausea, vomiting, diarrhea, and myalgia. Pregnant women experience a mild, flu-like illness with fever, muscle aches, upset stomach, and intestinal problems. Unfortunately, half of the newborns infected with Listeria will die from the illness.
alternative label: Circling disease
alternative label: Infection by Listeria monocytogenes
alternative label: Listeria infection
in_subset: gram-positive bacterial infectious disease
in_subset: zoonotic infectious disease

Liver disease
type: Class
subclass of: Hepatobiliary disease
alternative label: Hepatic disorder
alternative label: Hepatopathy
alternative label: Liver disorder

Louse-borne relapsing fever
type: Class
subclass of: Relapsing fever
definition: A relapsing fever that is characterized by relapsing or recurring episodes of fever, has_material basis_in Borrelia recurrentis, which is transmitted_by body louse (Pediculus humanus). The infection has_symptom tachypnea, has_symptom tachycardia, has_symptom hepatosplenomegaly and has_symptom lymphadenopathy.
alternative label: Louse-borne relaps fever
in_subset: gram-negative bacterial infectious disease

Lyme disease
type: Class
subclass of: Systemic disease
definition: A primary bacterial infectious disease that results_in infection, has_material_basis_in Borrelia burgdorferi, which is transmitted_by blacklegged tick (Ixodes scapularis) or transmitted_by western blacklegged tick (Ixodes pacificus). Symptoms include headache, chills, fever, erythema, muscle aches, joint pain, and fatigue.
alternative label: Bannwarth syndrome
alternative label: Bannworth's syndrome
alternative label: Lyme borreliosis
alternative label: Steere's disease
in_subset: gram-negative bacterial infectious disease
in_subset: tick-borne infectious disease
in_subset: zoonotic infectious disease

Lymphogranuloma venereum
type: Class
subclass of: Lymph node disease
definition: A commensal bacterial infectious disease that results_in infection located_in lymph nodes, has_material_basis_in Chlamydia trachomatis, which is transmitted_by sexual contact, and transmitted_by fomites. It is characterized by blister, swollen lymph nodes, and genital ulcer
alternative label: Chlamydial lymphogranuloma
alternative label: Durand-Nicolas-Favre disease
alternative label: Esthiomene
alternative label: Lymphogranuloma inguinale
alternative label: Poradenitis inguinale
alternative label: Strumous bubo
in_subset: gram-negative bacterial infectious disease
in_subset: sexually transmitted infectious disease

Mastitis
type: Class
subclass of: Breast disease
definition: An inflammation within the breast tissue that is usually caused by an infection. Most common pathogen is Staphylococcus aureus. General symptoms include swelling of breast, breast temderness/redness/hardness, itchy, painful in breast. Other symptoms are fever, nausea, vomiting, aches, shieving, and chills, fatigue, and increased heart rate.
alternative label: Inflammatory breast disease
alternative label: Inflammatory disease of breast

Mastoiditis
type: Class
subclass of: Middle ear disease
definition: An infection of the spaces within the mastoid bone within the skull. It is usually associated with otitis media. Mainly Streptococcus pneumoniae and Haemophilus infuenzae can cause the infection. Symptoms may include swelling of mastoid and fever.
alternative label: Mastoid empyema
alternative label: Mastoid empyemia

Melioidosis
type: Class
subclass of: Skin disease
subclass of: Lung disease
definition: A primary bacterial infectious disease that results_in infection, has_material_basis_in Burkholderia pseudomallei, which is transmitted_by contact with the contaminated water or soil. Symptoms include fever, osteomyelitis, pneumonia, septicemia, cough, and chest pain.
alternative label: Whitmore's disease
in_subset: gram-negative bacterial infectious disease
in_subset: zoonotic infectious disease

Meningitis
type: Class
subclass of: Central nervous system disease
definition: Meningitis is a nervous system infectious disease characterized by high fever, severe headache, stiff neck, and vomiting. It can be caused by growth of bacteria, fungi, or parasites within the subarachnoid space or by the growth of bacteria or viruses within the meningeal or ependymal cells. Meningitis is a diffuse infection caused by a variety of different agents.

Meningoencephalitis
type: Class
subclass of: Central nervous system disease
definition: A central nervous system disease that involves encephalitis which occurs along with meningitis.

Multiple sclerosis
type: Class
subclass of: Demyelinating disease
definition: A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring. Initial symptoms are muscle weakness, numbness, and visual disturbances.
alternative label: Disseminated sclerosis
alternative label: Generalized multiple sclerosis

Mushroom workers' lung
type: Class
subclass of: Extrinsic allergic alveolitis
definition: An extrinsic allergic alveolitis involving inflammation of the alveoli within the lung caused by hypersensitivity to the inhalation of organic dust particles derived from either the mushrooms, their spores or the compost in which the mushrooms are grown. It is usually caused by the spores of thermophilic actinomycetes.
alternative label: Mushroom worker's disease
alternative label: Mushroom-worker's lung
alternative label: Mushroom-workers' disease

Myocarditis
type: Class
subclass of: Heart disease
definition: An inflammatory of heart muscle (myocardium) caused by viral, bacterial, parasitic infection.
alternative label: Myocardial inflammation

Myositis
type: Class
subclass of: Myopathy
definition: A rare disease in which the muscle fibers and skin are inflamed and damaged. Symptoms include muscle pain and muscle weakness.
alternative label: Muscle inflammation

Necrotizing enterocolitis
type: Class
subclass of: Enterocolitis
definition: A serious bacterial infection in the intestine, primarily of sick or premature newborn infants. It can cause necrosis of intestinal tissue and septicemia. Early symptoms include abdominal distension, vomiting, and bloody stool.

Necrotizing fasciitis
type: Class
subclass of: Fasciitis
has date: A rare infection of the deeper layers of skin and subcutaneous tissues. Many types of bacteria such as Streptococcus pyogenes, Staphylococcus aureus, Clostridium perfringens, Bacteroides fragilis, Aeromonas hydrophila can cause the disease. Fever, skin redness, skin swelling are also common symptoms.
alternative label: Flesh-eating disease
in_subset: gram-positive bacterial infectious disease

Necrotizing pneumonia
type: Class
subclass of: Pneumonia
alternative label: Gangrenous pneumonia
alternative label: Necrotic pneumonia
definition: Necrotizing pneumonia is a rare complication of lung infection by Staphylococcus aureus.

Neonatal meningitis
type: Class
subclass of: Meningitis
definition: A disease characterized by inflammation of the meninges and occurring within the birth and the first 28 days of life. This is caused by Streptococcus pneumoniae, S. neonate.

Nocardiosis
type: Class
subclass of: Skin disease
subclass of: Lung disease
definition: An opportunistic bacterial infectious disease that results_in disseminated infection in immunocompromised hosts, has_material_basis_in Nocardia asteroides. Night sweats, cough, and chest pain are common symptoms.
in_subset: gram-positive bacterial infectious disease

Urethritis
type: Class
subclass of: Urethral disease
definition: An inflammation of the urethra that is usually caused by bacterial infection such as E. coli. Symptoms include pain and burning sensation on urinating, frequent urination, and blood in urine.
alternative label: Inflammation of urethra

Siberian tick typhus
type: Class
subclass of: Spotted fever
definition: A spotted fever that has_material_basis_in Rickettsia sibirica, which is transmitted_by ticks (Dermacentor nuttalli, Dermacentor marginatus and Haemaphysalis concinna). Symptoms are maculopapular rash, headache, conjunctival inflammation, and ulcer.
alternative label: North Asian tick fever
alternative label: North Asian tick typhus
in_subset: gram-negative bacterial infectious disease
in_subset: tick-borne infectious disease
in_subset: zoonotic infectious disease

Osteomyelitis
type: Class
subclass of: Bone inflammation disease
definition: A bone inflammation disease that has_material_basis_in infection located_in bone or located_in bone marrow. Bone pain and fever may occur.

Otitis
type: Class
subclass of: Auditory system disease
definition: An inflammation of the ear.
alternative label: Ear inflammation

Otitis media
type: Class
subclass of: Middle ear disease
definition: A otitis which involves inflammation of the middle ear. Symptoms include ear pain and fever.
alternative label: Middle ear inflammation

Paratyphoid fever
type: Class
subclass of: Intestinal disease
definition: A primary bacterial infectious disease that results_in infection located_in intestine, has_material_basis_in Salmonella enterica subsp enterica serovar Paratyphi A, B or C, which are transmitted_by ingestion of contaminated food. Symptoms include fever, headache, and splenomegaly.
in_subset: gram-negative bacterial infectious disease

Pasteurellosis
type: Class
subclass of: Systemic disease
definition: A primary bacterial infectious disease that results_in systemic infection, has_material_basis_in Pasteurella multocida, which is transmitted_by animal bite, scratch, or lick. Main symptoms are inflammation, fever, and pneumonia.
alternative label: Pasteurella infection
alternative label: Shipping fever
alternative label: Transport fever
in_subset: gram-negative bacterial infectious disease
in_subset: zoonotic infectious disease

Periodontitis
type: Class
subclass of: Periodontal disease
definition: An inflammatory disease that affects the periodontium within the oral cavity. Common symptoms include bleeding, and red gums.

Periodontosis
type: Class
subclass of: Tooth disease
definition: A widespread dental disease with consequent gum bleeding, sensitive inflamed gums and pocketing.

Peritonitis
type: Class
subclass of: Peritoneal disease
definition: A gastrointestinal system infectious disease that involves inflammation of the peritoneum resulting from perforation of the gastrointestinal tract, which produces immediate chemical inflammation followed shortly by infection from intestinal organisms. Peritonitis can also result from appendicitis, diverticulitis, strangulating intestinal obstruction, pancreatitis, pelvic inflammatory disease, mesenteric ischemia, intraperitoneal blood, barium, or peritoneo-systemic shunts, drains, and dialysis catheters in the peritoneal cavity. The symptoms include abdominal pain and tenderness, fever, nausea, and vomiting.

Pharyngitis
type: Class
subclass of: Upper respiratory tract disease
definition: An upper respiratory tract disease involving inflammation of the throat or pharynx resulting from bacterial, viral, fungal infections or irritants like pollutants or chemical substances and smoking.
alternative label: Irritation of the throat

Phlebitis
type: Class
subclass of: Vein disease
definition: Inflammation of a vein.

Pitted keratolysis
type: Class
subclass of: Skin disease
definition: A non-inflammatory, superficial infection of the stratum corneum of the skin. Main symptom is hyperhidrosis, malodor, and slimness of skin.
alternative label: Keratolysis plantare sulcatum
alternative label: Keratosis plantaris sulcatum

Pneumonia
type: Class
subclass of: Pneumonitis
definition: A lung disease that involves lung parenchyma or alveolar inflammation and abnormal alveolar filling with fluid (consolidation and exudation). It results from a variety of causes including infection with bacteria, viruses, fungi or parasites, and chemical or physical injury to the lungs. It is accompanied by fever, chills, cough, and difficulty in breathing.

Pneumonic plague
type: Class
subclass of: Pneumonia
definition: A plague that results_in infection located_in lung, which results from direct inhalation of the bacillus and has_symptom fever, has_symptom chills, has_symptom cough and has_symptom difficulty breathing.
in_subset: gram-negative bacterial infectious disease
in_subset: zoonotic infectious disease

Proctitis
type: Class
subclass of: Rectal disease
definition: A rectal disease that involves inflammation of the rectal mucosa, which results from infection, inflammatory bowel disease, or radiation. Sexually transmitted pathogens (Neisseria gonorrhoeae, Chlamydia trachomatis, herpes simplex virus 1 and 2, Treponema pallidum) and enteric pathogens (Campylobacter, Shigella, Salmonella) are involved in the disease. Symptoms are rectal discomfort and bleeding.

Psittacosis
type: Class
subclass of: Systemic disease
definition: A primary bacterial infectious disease that results_in systemic infection, has_material_basis_in Chlamydia psittaci, which is transmitted_by inhaling aerosolized dried droppings or transmitted_by contact with infected birds. The infection causes high fever, dry cough, and loss of appetite.
alternative label: Ornithosis
alternative label: Parrot fever
in_subset: gram-negative bacterial infectious disease
in_subset: zoonotic infectious disease

Pulmonary tuberculosis
type: Class
subclass of: Lung disease
definition: A tuberculosis that is a contagious disease located_in lungs. Symptoms include hemoptysis, chest pain, and prolonged cough.
in_subset: gram-positive bacterial infectious disease

Pyelitis
type: Class
subclass of: Kidney disease
definition: An inflammation of the renal pelvis.

Pyelonephritis
type: Class
subclass of: Pyelitis
definition: An inflammation of the kidney and upper urinary tract that usually results from non-contagious bacterial infection of the bladder (cystitis). E. coli, Klebsiella, Enterobacter, Proteus, or Psedomonas are common causes pyelonephritis. Symptoms include fever, chills, urinary frequency, back pain, nausea, and vomiting.

Q fever
type: Class
subclass of: Systemic disease
definition: A primary bacterial infectious disease that is a zoonotic infectious disease affecting multiple organs, has_material_basis_in Coxiella burnetii, which is transmitted_by inhalation of air contaminated by barnyard dust containing dried placental material, birth fluids, or excreta of infected herd animals, transmitted_by ingestion of contaminated milk, transmitted_by tick bites and transmitted_by contact with infected person. Symptoms include fever, chills, sweating, severe headache, nausea, diarrhea, vomiting, dry cough, mascle ache, loss of appetite, and fatigue.
alternative label: Balkan influenza
alternative label: Nine mile fever
alternative label: Quadrilateral fever
in_subset: gram-negative bacterial infectious disease
in_subset: zoonotic infectious disease

Rat-bite fever
type: Class
subclass of: Systemic disease
definition: An infection which develops after having been biten or scratched by Streptobacillus moniliformis-infected animal. Symptoms include fever, chills, nausea and vomiting, headache, back pain and joint pain.
alternative label: Rat bite fever
alternative label: Ratbite fever
alternative label: Sodoku
in_subset: zoonotic infectious disease

Rheumatic fever
type: Class
subclass of: Systemic disease
definition: An illness which arises as a complication of untreated or inadequately treated an infection of the oral pharynx and tonsils by streptococcus infection. Symptoms include joint pain, fever, polyarthritis, nodule, rash, and erythema.
alternative label: RhF
in_subset: gram-positive bacterial infectious disease

Rickettsialpox
type: Class
subclass of: Spotted fever
definition: A spotted fever that has_material_basis_in Rickettsia akari, which is transmitted_by house mouse mite (Liponyssoides sanguineus) found on mice and other rodents. Symptoms include fever, chills, sweating, headache, weakness, muscle pain, and rash.
alternative label: Kew Gardens spotted fever
alternative label: Vesicular rickettsiosis
in_subset: gram-negative bacterial infectious disease
in_subset: zoonotic infectious disease

Rickettsiosis
type: Class
subclass of: Systemic disease
definition: Any of a group of infectious diseases caused by microorganisms of the genus Rickettsia.
alternative label: Rickettsial disease
alternative label: Rickettsial infectious disease
in_subset: gram-negative bacterial infectious disease

Rocky Mountain spotted fever
type: Class
subclass of: Spotted fever
definition: A spotted fever that has_material_basis_in Rickettsia rickettsii, which is transmitted_by ticks (Dermacentor variabilis and Dermacentor andersoni). Symptoms include rash, high fever, chills, severe headache, prostration, and muscle pain.
alternative label: American tick typhus
alternative label: Brazillian spotted fever
alternative label: Sao Paulo typhus
alternative label: Tick typhus
alternative label: Tobia fever
in_subset: gram-negative bacterial infectious disease
in_subset: tick-borne infectious disease
in_subset: zoonotic infectious disease

Salmonellosis
type: Class
subclass of: Digestive system disease
definition: One of the most frequently occurring foodborne diseases worldwide by Salmonella enteritidis or Salmonella typhimurium infection. Symptom contains diarrhea, abdominal pain, fever, nausea, vomiting, and abdominal cramp.
alternative label: Salmonella Infection
in_subset: gram-negative bacterial infectious disease

Scrub typhus
type: Class
subclass of: Typhus
definition: A typhus that has_material_basis_in Orientia tsutsugamushi, which is transmitted_by trombiculid mites (Leptotrombidium deliense). Main symptoms are fever, severe headache, chills, rash, lymphadenopathy, and muscle pain.
alternative label: Japanese river fever
alternative label: Kedani fever
alternative label: Mite-borne typhus
alternative label: Scrub mite-borne typhus
alternative label: Tsutsugamushi Fever
alternative label: Tsutsugamushi disease
in_subset: gram-negative bacterial infectious disease
in_subset: zoonotic infectious disease

Sennetsu fever
type: Class
subclass of: Rickettsiosis
definition: A primary bacterial infectious disease that results_in infection, has_material_basis_in Neorickettsia sennetsu, which is transmitted_by ingestion of raw or under-cooked gray mullet fish infected with the trematodes. It is characterized by headache, nausea, lymphocytosis, and lymphadenopathy.
alternative label: Sennetsu ehrlichiosis
in_subset: gram-negative bacterial infectious disease
in_subset: zoonotic infectious disease

Septicemia
type: Class
subclass of: Systemic disease
definition: A systemic infection associated with the presence and persistence of pathogenic microorganisms or their toxins in the stream or body tissues. It causes fever, rapid heart rate, and rapid breathing.
alternative label: Blood poisoning
alternative label: Sepsis

Shigellosis
type: Class
subclass of: Dysentery
subclass of: Food poisoning
definition: A primary bacterial infectious disease that results_in infection located_in epithelium of colon, has_material_basis_in Shigella boydii, has_material_basis_in Shigella dysenteriae, has_material_basis_in Shigella flexneri, or has_material_basis_in Shigella sonnei, which produce toxins that can attack the lining of the large intestine, causing diarrhea, fever, abdominal pain, tenesmus, bloody stool, and abdominal cramps. The bacteria are transmitted_by ingestion of food and water contaminated with feces.
alternative label: Bacillary dysentery
alternative label: Japanese dysentery
alternative label: Shigella dysentery
alternative label: Shigella gastroenteritis
in_subset: gram-negative bacterial infectious disease

Sinusitis
type: Class
subclass of: Paranasal sinus disease
definition: A paranasal sinus disease involving inflammation of the paranasal sinuses resulting from bacterial, fungal, viral infection, allergic or autoimmune issues. Symptoms can include pain, headache, fever, tenderness, and nasal discharge. There may also be mucus drainage in the back of the throat, called postnasal drip.

Skin ulcer
type: Class
subclass of: Skin lesion
alternative label: Skin ulceration

Soft tissue lesion
type: Class
subclass of: Soft tissue disease
alternative label: Soft tissue lesions

Spondylodiscitis
type: Class
subclass of: Bone inflammation disease
definition: A rare bacterial infection of the spine with an inflammatory, destructive course. The most frequent symptoms are back pain and fever.
alternative label: Discitis

Spontaneous abortion
type: Class
subclass of: Abortion
definition: A major complication in pregnancy. Certain factors such as uterine abnormalities, hormonal disturbances, chromosomal abnormalities, and infectious agents are considered to be causal factors in recurrent abortion. Bleeding and discharge from th vagina, and cramping may occur.
alternative label: Miscarriage

Spotted fever
type: Class
subclass of: Rickettsiosis
definition: A primary bacterial infectious disease that results_in infection, located_in endothelial cell of artery or located_in endothelial cell of vein, has_material_basis_in Rickettsia, which is transmitted_by ticks and mites.
alternative label: Spotted fevers
alternative label: Tick-borne rickettsioses
in_subset: gram-negative bacterial infectious disease

Staphylococcal scarlet fever
type: Class
subclass of: Scarlet fever
definition: A more rare form of scarlet fever. The signs and symptoms are indistinguishable from scarlet fever caused by Streptococcus except that throat infection is usually absent.
alternative label: Staphylococcal scarlatina
in_subset: gram-positive bacterial infectious disease

Hordeolum
type: Class
subclass of: Eyelid disease
definition: An infection of the sebaceous glands at the base of the eyelashes generally caused by Staphylococcus aureus. Symptoms are pain, redness, and tenderness near the eyelid margin.
alternative label: Boil of eyelid
alternative label: Furuncle of eyelid
alternative label: Stye
alternative label: Styes

Septic arthritis
type: Class
subclass of: Arthritis
definition: An infection in the fluid and tissues of a joint caused mainly by bacteria. Symptoms include joint pain and joint swelling.
alternative label: Bacterial arthritis
alternative label: Infectious arthritis
alternative label: Pyogenic arthritis
alternative label: Suppurative arthritis

Syphilis
type: Class
subclass of: Reproductive system disease
definition: A primary bacterial infectious disease that is a sexually transmitted systemic disease, has_material_basis_in Treponema pallidum subsp pallidum, which is transmitted_by sexual contact, transmitted_by blood product transfusion, transmitted_by congenital method from mother to fetus or transmitted_by contact with infectious lesions. It causes chancre, swollen lymph nodes, anorexia, and fever.
alternative label: Lues
alternative label: Luetic disease
alternative label: Treponemal infection
in_subset: gram-negative bacterial infectious disease
in_subset: sexually transmitted infectious disease

Tetanus
type: Class
subclass of: Nervous system disease
subclass of: Muscular disease
definition: A primary bacterial infectious disease that results in lockjaw, spasm, difficulty in swallowing. It caused by Clostridium tetani, which produces tetanospasmin, a neurotoxin, which is carried to the brain and spinal cord. Damaged upper motor neurons cannot control reflex responses to afferent sensory stimuli.
alternative label: Lockjaw
in_subset: gram-positive bacterial infectious disease

Tick-borne relapsing fever
type: Class
subclass of: Relapsing fever
definition: A relapsing fever that is characterized by relapsing or recurring episodes of fever, has_material basis_in Borrelia hermsii, has_material basis_in Borrelia parkeri or has_material basis_in Borrelia duttoni, which are transmitted_by soft ticks (Ornithodoros parkeri and Ornithodoros hermsii). The infection has_symptom tachypnea, has_symptom tachycardia, has_symptom hepatosplenomegaly and has_symptom lymphadenopathy.
alternative label: Tick-borne relaps fever
in_subset: gram-negative bacterial infectious disease
in_subset: tick-borne infectious disease
in_subset: zoonotic infectious disease

Tonsillitis
type: Class
subclass of: Upper respiratory tract disease
definition: An upper respiratory tract disease which involves inflammation of the tonsils resulting from bacterial (Group A streptococcus) and viral (Epstein-Barr virus, adenovirus) infections. Symptoms include a severe sore throat (which may be experienced as referred pain to the ears), painful/difficult swallowing, coughing, headache, myalgia (muscle aches), fever and chills. Tonsillitis is characterized by sore throat, difficult swallowing, earache, fever, swollen neck, malaise, chills, and body pain.
alternative label: Tonsillitides

Toxic shock syndrome
type: Class
subclass of: Systemic disease
definition: A commensal bacterial infectious disease that results_in infection, has_material_basis_in Streptococcus pyogenes or has_material_basis_in Staphylococcus aureus , which produce toxins that are absorbed systemically and produce the systemic manifestations. Symptoms include high fever, vomiting, diarrhea, headache, rash, sore throat, and muscle pain.
alternative label: Septic shock
alternative label: TSS
alternative label: Toxic shock
alternative label: Toxic-shock syndrome
in_subset: gram-positive bacterial infectious disease

Tracheobronchitis
type: Class
subclass of: Respiratory system disease
definition: Inflammation of the mucous membrane of the trachea and bronchi.

Trachoma
type: Class
subclass of: Globe disease
definition: A commensal bacterial infectious disease that results_in infection located_in eye, has_material_basis_in Chlamydia trachomatis (A, B, Ba and C serovars), which is transmitted_by contact with eye discharge from the infected person and transmitted_by congenital method. Symptoms include eyelids pain, swollen eyelids, eye discharge, tearing, and sensitivity to light.
alternative label: Egyptian ophthalmia
in_subset: gram-negative bacterial infectious disease

Trench fever
type: Class
subclass of: Bartonellosis
definition: A primary bacterial infectious disease that results_in systemic infection, has_material_basis_in Bartonella quintana, which is transmitted_by body lice (Pediculus humanus corporis). The infection has_symptom relapsing fever, has_symptom headache, has_symptom fever, dizziness, rash, and leg pain.
alternative label: Febris quintata
alternative label: Five day fever
alternative label: Quintan fever
alternative label: Trench fevers
in_subset: gram-negative bacterial infectious disease

Tuberculosis
type: Class
subclass of: Disease involving unidentified body site
definition: A primary bacterial infectious disease that is located_in lungs, located_in lymph nodes, located_in pericardium, located_in brain, located_in pleura or located_in gastrointestinal tract, has_material_basis_in Mycobacterium tuberculosis, which is transmitted_by droplets released into the air when an infected person coughs or sneezes. It causes cough, sweating, shortness breath, chest pain, fatigue, poor appetite, fever, sweating, and weight loss.
alternative label: Mycobacterium tuberculosis infection
alternative label: TB
in_subset: gram-positive bacterial infectious disease

Tularemia
type: Class
subclass of: Disease involving unidentified body site
definition: A primary bacterial infectious disease that has_material_basis_in Francisella tularensis, which is transmitted_by dog tick bite (Dermacentor variabilis), transmitted_by deer flies (Chrysops sp) or transmitted_by contact with infected animal tissues. Main symptoms are fever and swollen lymph nodes.
alternative label: Deer fly fever
alternative label: Francis' disease
alternative label: Ohara's disease
alternative label: Pahvant valley fever
alternative label: Rabbit fever
alternative label: Yatobyo
in_subset: gram-negative bacterial infectious disease
in_subset: tick-borne infectious disease
in_subset: zoonotic infectious disease

Typhoid fever
type: Class
subclass of: Systemic disease
definition: A primary bacterial infectious disease that is a communicable systemic illness, has_material_basis_in Salmonella enterica subsp enterica serovar Typhi, which is transmitted_by ingestion of food or water contaminated with the feces of an infected person. Symptoms include high fever, constipation, prostration, rose spots, cough, and diarrhea.
alternative label: Abdominal typhus
alternative label: Enteric fever
alternative label: Typhoid
alternative label: Typhoids
in_subset: gram-negative bacterial infectious disease

Typhus
type: Class
subclass of: Systemic disease
definition: A primary bacterial infectious disease that refers to a group of diseases, located_in endothelial cells of the small venous, arterial, and capillary vessels, has_material_basis_in Rickettsia bacteria, which are transmitted_by lice, transmitted_by fleas, and transmitted_by mites.
alternative label: Typhus fever
in_subset: gram-negative bacterial infectious disease
in_subset: zoonotic infectious disease

Urolithiasis
type: Class
subclass of: Urinary system disease
definition: The formation of urinary calculi, or the condition associated with urinary calculi. Symptoms include abdominal pain and hematuria.
alternative label: Urinary calculosis
alternative label: Urinary lithiasis

Urinary tract infection
type: Class
subclass of: Urinary system disease
definition: A bacterial infection in the urethra, bladder, ureters, or kidneys caused by Enterobacteriaceae including E. coli, Klebsiella sp., Proteus sp., Pseudomonas sp., or Enterococcus sp. Symptoms include urinary frequency, burning pain on urination, hematuria, and pus in the urine.
alternative label: UTI

Whipple disease
type: Class
subclass of: Intestinal disease
definition: A relatively rare malabsorptive disorder caused by Tropheryma whipplei. Symptoms include diarrhea, abdominal pain, weight loss, joint pain, darkness of skin, arthritis, and steatorrhea.
alternative label: Intestinal lipodystrophy
alternative label: Whipple's disease
in_subset: gram-positive bacterial infectious disease

Yaws
type: Class
subclass of: Skin disease
subclass of: Bone disease
definition: A primary bacterial infectious disease that results_in infection located_in skin, located_in joint or located_in bone, has_material_basis_in Treponema pallidum subsp pertenue, which is transmitted_by direct skin contact with an infected person. The infection has_symptom skin lesions.
alternative label: Bouba
alternative label: Buba
alternative label: Frambesia
alternative label: Frambesia tropica
alternative label: Framboesia
alternative label: Pian
in_subset: gram-negative bacterial infectious disease

Enteritis
type: Class
subclass of: Intestinal disease
definition: Inflammation of the small intestine.

Aggressive periodontitis
type: Class
subclass of: Periodontosis
definition: A periodontal disease that manifests before age 35. It causes rapid loss of the periodontium and does not respond easily to periodontal treatment.
alternative label: Juvenile periodontitis

Cat scratch disease
type: Class
subclass of: Lymph node disease
definition: A primary bacterial infectious disease that results_in infection located_in lymph node, has_material_basis_in Bartonella henselae or has_material_basis_in Bartonella clarridgeiae, which are transmitted_by scratch or bite of a kitten, or transmitted_by contact of animal's saliva with an eye or through broken skin. The infection causes lymphadenopathy.
alternative label: Cat scratch fever
in_subset: gram-negative bacterial infectious disease
in_subset: tick-borne infectious disease
in_subset: zoonotic infectious disease

Cervicitis
type: Class
subclass of: Uterine disease
definition: An inflammation of the cervix (the opening into the uterus). Symptoms incluse vaginal discharge, bleeding, and itching.

Discitis
type: Class
subclass of: Bone inflammation disease
definition: An infection in the intervertebral disc space.
alternative label: Diskitis

Duodenal ulcer
type: Class
subclass of: Peptic ulcer
definition: A peptic ulcer situated in the duodenum.

Endodontic disease
type: Class
subclass of: Tooth disease
definition: An infection of the dental root canal system and the major etiologic agent of apical periodontitis.
alternative label: Disorder of pulp of tooth

Male reproductive system disease
type: Class
subclass of: Reproductive system disease
alternative label: Disorder of male genital system
alternative label: Male genital disease

Epididymitis
type: Class
subclass of: Male reproductive system disease
definition: An inflammation or infection of the epididymis. Symptoms include swelling, tenderness, and pain.

Flea-borne spotted fever
type: Class
subclass of: Spotted fever
definition: A typhus that has_material_basis_in Rickettsia typhi or has_material_basis_in Rickettsia felis, which are transmitted_by fleas (Xenopsylla cheopis).

Guillain-Barre syndrome
type: Class
subclass of: Peripheral nervous system disease
alternative label: Acute infective polyneuritis
definition: An autoimmune disease of peripheral nervous system that causes body's immune system to attack part of the peripheral nervous system. It is characterized by muscle weakness and sensory loss.
alternative label: Guillain–Barré syndrome
alternative label: Infectious neuronitis
alternative label: Post-infectious polyneuritis

Hemolytic-uremic syndrome
type: Class
subclass of: Kidney disease
definition: A rare kidney disorder marked by renal failure, hemolytic anemia, and thrombocytopenia .
alternative label: Hemolytic uremic syndrome

Japanese spotted fever
type: Class
subclass of: Spotted fever
definition: A spotted fever that has_material_basis_in Rickettsia japonica, which is transmitted_by ticks (Dermacentor taiwanensis and Haemaphysalis flava). Main symptoms are headache, fever, and rash.
alternative label: Oriental spotted fever
in_subset: gram-negative bacterial infectious disease
in_subset: tick-borne infectious disease
in_subset: zoonotic infectious disease

Boutonneuse fever
type: Class
subclass of: Spotted fever
definition: A spotted fever that has_material_basis_in Rickettsia conorii subsp conorii, which is transmitted_by dog tick (Rhipicephalus sanguineus). Symptoms are chills, fever, skin lesion, and rash.
alternative label: Boutonneuse disease
alternative label: Mediterranean spotted fever
in_subset: gram-negative bacterial infectious disease
in_subset: tick-borne infectious disease
in_subset: zoonotic infectious disease

Mycobacterium avium-intracellulare infection
type: Class
subclass of: Lung disease
definition: An infection caused by Mycobacterium avium complex (MAC), which consists of two species: M. avium and M. intracellulare. Symptoms of the disseminated infection include fever, weight loss, and malaise.

Neonatal pneumonia
type: Class
subclass of: Pneumonia

Non-gonococcal urethritis
type: Class
subclass of: Urethritis
definition: An inflammation of the urethra not due to gonorrhea, almost always contracted through sexual intercourse and found far more often in men. It causes dysuria and discharge.
alternative label: Nongonococcal urethritis
alternative label: Nonspecific urethritis

Pelvic inflammatory disease
type: Class
subclass of: Female reproductive system disease
definition: An infection in the lower female reproductive tract that spreads to the upper female reproductive tract. The lower female genital tract consists of the vagina and the cervix. The upper female genital tract consists of the body of the uterus, the fallopian or uterine tubes, and the ovaries. Symptoms include abdominal pain, vaginal bleeding, and vaginal discharge.

Peritoneal disease
type: Class
subclass of: Digestive system disease
alternative label: Peritoneal disorder

Pertussis
type: Class
subclass of: Upper respiratory tract disease
definition: A commensal bacterial infectious disease that results_in inflammation located_in respiratory tract, has_material_basis_in Bordetella pertussis, or has_material_basis_in Bordetella parapertussis, which produce toxins that paralyze the cilia of the respiratory epithelial cells. The infection is characterized by sneezing, loss of appetite, runny nose, cough, and malaise.
alternative label: Whooping cough
in_subset: gram-negative bacterial infectious disease

Pleural disease
type: Class
subclass of: Lower respiratory tract disease
alternative label: Pleural disorder

Primary biliary cirrhosis
type: Class
subclass of: Liver disease
definition: The gradual destruction of the biliary system for unknown reasons. Symptoms include itching, fatigue, and jaundice.

Pyoderma
type: Class
subclass of: Dermatitis
alternative label: Purulent dermatitis
definition: Pyoderma is a skin infectious disease where the infection is pyogenic causing the formation of pus.
alternative label: Suppurative dermatitis

Retinitis
type: Class
subclass of: Globe disease
definition: An inflammation of the retina.

Rheumatoid arthritis
type: Class
subclass of: Arthritis
definition: A chronic autoimmune disease that causes inflammation and deformity of the joints. Symptoms include joint pain, joint stiffness, and joint swelling.

Streptococcal toxic shock syndrome
type: Class
subclass of: Toxic shock syndrome

Tick-borne lymphadenopathy
type: Class
subclass of: Spotted fever
definition: A tick-transmitted disease by Rickettsia slovaca. It is characterized by lymphadenopathy, rash, eschar, and muscle pain. Other symptoms include fatigue, dizziness, headache, sweat, arthralgia, and loss of appetite.
alternative label: TIBOLA

Vulvovaginitis
type: Class
subclass of: Uterine disease
definition: An inflammation of the vagina and vulva most often caused by a bacterial, fungal, or parasitic infection. Vaginal discharge, irritation, and itching are common symptom.

Cat flea typhus
type: Class
subclass of: Flea-borne spotted fever
definition: A typhus-like infectious disease caused by Rickettsia felis. It is characterized by fever and rash. Headache, exanthem, and neurologic and visceral signs may occur.
alternative label: ICD10CM_2011_01:A77.8
alternative label: UMLS_CUI:C1563188

Liver damage
type: Class
subclass of: Liver disease
definition: A damage to the liver parenchyma causing some degree of hepatic insufficiency.

Skin lesion
type: Class
subclass of: Skin disease
alternative label: Skin lesions